locus-tag	class	description
CSC3H3_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CSC3H3_00010	COG0592	DNA-directed DNA polymerase activity
CSC3H3_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CSC3H3_00020	COG0187	DNA topoisomerase II activity
CSC3H3_00025	COG0028	Belongs to the TPP enzyme family
CSC3H3_00030	COG1802	Transcriptional regulator
CSC3H3_00035	COG2084	Dehydrogenase
CSC3H3_00040	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CSC3H3_00045	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CSC3H3_00050	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CSC3H3_00060	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CSC3H3_00065	COG4221	oxidoreductase activity
CSC3H3_00070	COG4977	sequence-specific DNA binding
CSC3H3_00090	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CSC3H3_00095	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CSC3H3_00120	COG0583	DNA-binding transcription factor activity
CSC3H3_00125	COG1280	lysine exporter protein (LysE YggA)
CSC3H3_00135	COG0137	argininosuccinate synthase activity
CSC3H3_00150	COG0330	HflC and HflK could
CSC3H3_00160	COG1346	cytolysis
CSC3H3_00175	COG1393	Belongs to the ArsC family
CSC3H3_00180	COG2137	regulation of response to DNA damage stimulus
CSC3H3_00185	COG0842	Transport permease protein
CSC3H3_00190	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CSC3H3_00195	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CSC3H3_00200	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CSC3H3_00220	COG1595	DNA-templated transcription, initiation
CSC3H3_00230	COG0589	response to stress
CSC3H3_00235	COG0659	secondary active sulfate transmembrane transporter activity
CSC3H3_00240	COG0840	transmembrane signaling receptor activity
CSC3H3_00245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSC3H3_00260	COG0242	peptide deformylase activity
CSC3H3_00310	COG0745	RESPONSE REGULATOR receiver
CSC3H3_00315	COG2205	protein histidine kinase activity
CSC3H3_00320	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CSC3H3_00330	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSC3H3_00330	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC3H3_00340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CSC3H3_00345	COG3667	copper resistance
CSC3H3_00350	COG2132	Multicopper oxidase
CSC3H3_00365	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CSC3H3_00385	COG0583	DNA-binding transcription factor activity
CSC3H3_00410	COG0519	Catalyzes the synthesis of GMP from XMP
CSC3H3_00425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSC3H3_00430	COG0569	domain protein
CSC3H3_00435	COG1078	dGTPase activity
CSC3H3_00440	COG2205	protein histidine kinase activity
CSC3H3_00475	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CSC3H3_00480	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CSC3H3_00485	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CSC3H3_00505	COG2816	NAD+ diphosphatase activity
CSC3H3_00540	COG0583	DNA-binding transcription factor activity
CSC3H3_00555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CSC3H3_00560	COG2171	N-acyltransferase activity
CSC3H3_00570	COG2203	Gaf domain
CSC3H3_00570	COG3706	GGDEF domain
CSC3H3_00570	COG4251	negative regulation of phosphorylation
CSC3H3_00570	COG5001	Diguanylate cyclase
CSC3H3_00575	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSC3H3_00580	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CSC3H3_00635	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CSC3H3_00645	COG3300	MHYT domain
CSC3H3_00645	COG5001	Diguanylate cyclase
CSC3H3_00650	COG4191	Histidine kinase
CSC3H3_00650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSC3H3_00670	COG0512	Glutamine amidotransferase of anthranilate synthase
CSC3H3_00670	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CSC3H3_00675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CSC3H3_00690	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CSC3H3_00700	COG0840	transmembrane signaling receptor activity
CSC3H3_00725	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CSC3H3_00750	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSC3H3_00760	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CSC3H3_00765	COG3706	GGDEF domain
CSC3H3_00780	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSC3H3_00785	COG5002	protein histidine kinase activity
CSC3H3_00795	COG0398	Pfam SNARE associated Golgi protein
CSC3H3_00810	COG0302	gtp cyclohydrolase
CSC3H3_00815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CSC3H3_00825	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CSC3H3_00830	COG0390	transport system, permease component
CSC3H3_00840	COG0662	Cupin 2, conserved barrel domain protein
CSC3H3_00845	COG0534	Mate efflux family protein
CSC3H3_00850	COG0584	glycerophosphoryl diester phosphodiesterase
CSC3H3_00885	COG1971	Probably functions as a manganese efflux pump
CSC3H3_00905	COG1396	sequence-specific DNA binding
CSC3H3_00945	COG1522	sequence-specific DNA binding
CSC3H3_00960	COG0628	permease
CSC3H3_00980	COG0784	Response regulator, receiver
CSC3H3_00980	COG2205	protein histidine kinase activity
CSC3H3_00980	COG5002	protein histidine kinase activity
CSC3H3_00985	COG5001	Diguanylate cyclase
CSC3H3_00985	COG2203	Gaf domain
CSC3H3_00985	COG3706	GGDEF domain
CSC3H3_00985	COG4251	negative regulation of phosphorylation
CSC3H3_00990	COG0745	RESPONSE REGULATOR receiver
CSC3H3_01055	COG3383	formate dehydrogenase (NAD+) activity
CSC3H3_01065	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CSC3H3_01070	COG0583	DNA-binding transcription factor activity
CSC3H3_01085	COG4191	Histidine kinase
CSC3H3_01090	COG2204	response regulator
CSC3H3_01100	COG0243	molybdopterin cofactor binding
CSC3H3_01150	COG2828	Protein conserved in bacteria
CSC3H3_01170	COG0583	DNA-binding transcription factor activity
CSC3H3_01190	COG0668	transmembrane transport
CSC3H3_01200	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CSC3H3_01210	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSC3H3_01215	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CSC3H3_01215	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSC3H3_01265	COG0420	3'-5' exonuclease activity
CSC3H3_01285	COG4372	Transposase
CSC3H3_01335	COG4962	Type ii secretion system protein e
CSC3H3_01440	COG0024	Methionine aminopeptidase
CSC3H3_01445	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CSC3H3_01460	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CSC3H3_01470	COG2081	HI0933 family
CSC3H3_01475	COG3706	GGDEF domain
CSC3H3_01500	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CSC3H3_01505	COG3806	Anti-sigma factor
CSC3H3_01510	COG1595	DNA-templated transcription, initiation
CSC3H3_01525	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CSC3H3_01555	COG0564	pseudouridine synthase activity
CSC3H3_01565	COG1803	Methylglyoxal synthase
CSC3H3_01570	COG0583	DNA-binding transcription factor activity
CSC3H3_01575	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CSC3H3_01620	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSC3H3_01630	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CSC3H3_01635	COG0045	succinate-CoA ligase (ADP-forming) activity
CSC3H3_01640	COG0039	L-malate dehydrogenase activity
CSC3H3_01650	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CSC3H3_01665	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CSC3H3_01665	COG3264	Mechanosensitive ion channel
CSC3H3_01680	COG0494	nUDIX hydrolase
CSC3H3_01690	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CSC3H3_01695	COG0174	glutamine synthetase
CSC3H3_01710	COG0625	glutathione transferase activity
CSC3H3_01720	COG4974	Belongs to the 'phage' integrase family
CSC3H3_01730	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CSC3H3_01750	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CSC3H3_01760	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CSC3H3_01770	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CSC3H3_01775	COG0300	oxidoreductase activity
CSC3H3_01780	COG0583	DNA-binding transcription factor activity
CSC3H3_01785	COG0784	Response regulator, receiver
CSC3H3_01790	COG4235	cytochrome complex assembly
CSC3H3_01795	COG1138	Cytochrome C-type biogenesis protein
CSC3H3_01805	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CSC3H3_01810	COG1702	phosphate starvation-inducible protein PhoH
CSC3H3_01865	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CSC3H3_01870	COG0431	NADPH-dependent FMN reductase
CSC3H3_01910	COG0519	Catalyzes the synthesis of GMP from XMP
CSC3H3_01915	COG3842	ATPase activity
CSC3H3_01925	COG1178	ABC-type Fe3 transport system permease component
CSC3H3_01935	COG1872	DUF167
CSC3H3_01940	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CSC3H3_01945	COG3214	Protein conserved in bacteria
CSC3H3_01950	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_01970	COG1653	transport
CSC3H3_01980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CSC3H3_01990	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CSC3H3_02005	COG1595	DNA-templated transcription, initiation
CSC3H3_02020	COG0066	3-isopropylmalate dehydratase activity
CSC3H3_02030	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CSC3H3_02040	COG4106	trans-aconitate 2-methyltransferase activity
CSC3H3_02055	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CSC3H3_02060	COG0228	four-way junction DNA binding
CSC3H3_02065	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CSC3H3_02085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CSC3H3_02095	COG2217	Heavy metal translocating P-type atpase
CSC3H3_02125	COG0583	DNA-binding transcription factor activity
CSC3H3_02140	COG2010	Cytochrome c
CSC3H3_02165	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CSC3H3_02170	COG0126	phosphoglycerate kinase activity
CSC3H3_02180	COG1131	(ABC) transporter
CSC3H3_02220	COG4106	trans-aconitate 2-methyltransferase activity
CSC3H3_02230	COG0494	nUDIX hydrolase
CSC3H3_02240	COG0793	Belongs to the peptidase S41A family
CSC3H3_02245	COG4942	peptidase
CSC3H3_02250	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CSC3H3_02255	COG1760	l-serine dehydratase
CSC3H3_02260	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CSC3H3_02280	COG0799	negative regulation of ribosome biogenesis
CSC3H3_02285	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CSC3H3_02300	COG5265	(ABC) transporter
CSC3H3_02330	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CSC3H3_02335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSC3H3_02340	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CSC3H3_02365	COG1196	nuclear chromosome segregation
CSC3H3_02370	COG5336	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex
CSC3H3_02380	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CSC3H3_02385	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CSC3H3_02395	COG0435	Glutathione S-transferase
CSC3H3_02400	COG0583	DNA-binding transcription factor activity
CSC3H3_02420	COG0714	Associated with various cellular activities
CSC3H3_02455	COG3300	MHYT domain
CSC3H3_02455	COG5001	Diguanylate cyclase
CSC3H3_02460	COG4974	Belongs to the 'phage' integrase family
CSC3H3_02475	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CSC3H3_02480	COG4536	flavin adenine dinucleotide binding
CSC3H3_02485	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CSC3H3_02485	COG0517	IMP dehydrogenase activity
CSC3H3_02500	COG0271	Belongs to the BolA IbaG family
CSC3H3_02520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CSC3H3_02535	COG0625	glutathione transferase activity
CSC3H3_02545	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CSC3H3_02555	COG4774	siderophore transport
CSC3H3_02570	COG1238	metal cluster binding
CSC3H3_02640	COG4948	Mandelate Racemase Muconate Lactonizing
CSC3H3_02645	COG0583	DNA-binding transcription factor activity
CSC3H3_02650	COG0473	3-isopropylmalate dehydrogenase activity
CSC3H3_02670	COG3181	Tripartite tricarboxylate transporter family receptor
CSC3H3_02675	COG0583	DNA-binding transcription factor activity
CSC3H3_02680	COG5002	protein histidine kinase activity
CSC3H3_02695	COG1396	sequence-specific DNA binding
CSC3H3_02695	COG3800	Transcriptional regulator
CSC3H3_02705	COG0559	Belongs to the binding-protein-dependent transport system permease family
CSC3H3_02720	COG0410	ABC transporter
CSC3H3_02730	COG1522	sequence-specific DNA binding
CSC3H3_02750	COG0019	diaminopimelate decarboxylase activity
CSC3H3_02760	COG1309	transcriptional regulator
CSC3H3_02770	COG1609	Transcriptional regulator
CSC3H3_02775	COG1129	ABC transporter
CSC3H3_02780	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC3H3_02785	COG1879	ABC-type sugar transport system periplasmic component
CSC3H3_02800	COG0673	inositol 2-dehydrogenase activity
CSC3H3_02835	COG1522	sequence-specific DNA binding
CSC3H3_02840	COG3608	succinylglutamate desuccinylase aspartoacylase
CSC3H3_02845	COG0006	proline dipeptidase activity
CSC3H3_02850	COG2423	ornithine cyclodeaminase activity
CSC3H3_02855	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CSC3H3_02865	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CSC3H3_02870	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CSC3H3_02875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSC3H3_02880	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CSC3H3_02885	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CSC3H3_02915	COG4214	carbohydrate transport
CSC3H3_02925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CSC3H3_02930	COG1012	belongs to the aldehyde dehydrogenase family
CSC3H3_02940	COG1132	(ABC) transporter
CSC3H3_02940	COG1132	(ABC) transporter
CSC3H3_02945	COG1234	tRNA 3'-trailer cleavage
CSC3H3_02960	COG1733	regulation of RNA biosynthetic process
CSC3H3_02965	COG0604	alcohol dehydrogenase
CSC3H3_02985	COG3706	GGDEF domain
CSC3H3_02985	COG0745	RESPONSE REGULATOR receiver
CSC3H3_03035	COG3706	GGDEF domain
CSC3H3_03055	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CSC3H3_03060	COG0280	phosphate acetyltransferase
CSC3H3_03060	COG0281	malic enzyme
CSC3H3_03065	COG2239	Acts as a magnesium transporter
CSC3H3_03115	COG0708	Exodeoxyribonuclease III
CSC3H3_03180	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CSC3H3_03190	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CSC3H3_03195	COG0706	membrane insertase activity
CSC3H3_03200	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CSC3H3_03205	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CSC3H3_03210	COG3706	GGDEF domain
CSC3H3_03215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CSC3H3_03220	COG0552	protein localization to endoplasmic reticulum
CSC3H3_03260	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CSC3H3_03280	COG0742	ribosomal rna small subunit methyltransferase
CSC3H3_03285	COG1187	pseudouridine synthase activity
CSC3H3_03290	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CSC3H3_03295	COG0590	tRNA wobble adenosine to inosine editing
CSC3H3_03300	COG0300	oxidoreductase activity
CSC3H3_03310	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CSC3H3_03325	COG3550	peptidyl-serine autophosphorylation
CSC3H3_03335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC3H3_03340	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CSC3H3_03350	COG2204	response regulator
CSC3H3_03355	COG3852	Histidine kinase
CSC3H3_03360	COG0151	Belongs to the GarS family
CSC3H3_03365	COG1570	exodeoxyribonuclease VII activity
CSC3H3_03375	COG0405	Gamma-glutamyltransferase
CSC3H3_03380	COG1846	Transcriptional regulator
CSC3H3_03395	COG1663	tetraacyldisaccharide 4'-kinase activity
CSC3H3_03400	COG1519	Transferase
CSC3H3_03410	COG1132	(ABC) transporter
CSC3H3_03420	COG0438	transferase activity, transferring glycosyl groups
CSC3H3_03430	COG1597	lipid kinase activity
CSC3H3_03450	COG0840	transmembrane signaling receptor activity
CSC3H3_03470	COG0840	transmembrane signaling receptor activity
CSC3H3_03475	COG0840	transmembrane signaling receptor activity
CSC3H3_03480	COG0840	transmembrane signaling receptor activity
CSC3H3_03485	COG0312	modulator of DNA gyrase
CSC3H3_03505	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CSC3H3_03525	COG0583	DNA-binding transcription factor activity
CSC3H3_03530	COG2814	Major facilitator Superfamily
CSC3H3_03535	COG2264	protein methyltransferase activity
CSC3H3_03540	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CSC3H3_03570	COG3639	organic phosphonate transmembrane transporter activity
CSC3H3_03585	COG1349	DNA-binding transcription factor activity
CSC3H3_03595	COG0114	fumarate hydratase activity
CSC3H3_03620	COG1280	lysine exporter protein (LysE YggA)
CSC3H3_03630	COG4608	Belongs to the ABC transporter superfamily
CSC3H3_03635	COG0444	Belongs to the ABC transporter superfamily
CSC3H3_03640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC3H3_03645	COG0601	transmembrane transport
CSC3H3_03650	COG0747	negative chemotaxis
CSC3H3_03680	COG0312	modulator of DNA gyrase
CSC3H3_03690	COG1612	heme a metabolic process
CSC3H3_03695	COG1648	precorrin-2 dehydrogenase activity
CSC3H3_03695	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CSC3H3_03700	COG0175	sulfate reduction
CSC3H3_03705	COG1228	amidohydrolase
CSC3H3_03715	COG3046	protein related to deoxyribodipyrimidine photolyase
CSC3H3_03735	COG1522	sequence-specific DNA binding
CSC3H3_03740	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CSC3H3_03750	COG4953	penicillin-binding protein 1C
CSC3H3_03760	COG0583	DNA-binding transcription factor activity
CSC3H3_03765	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CSC3H3_03775	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CSC3H3_03780	COG3265	gluconokinase activity
CSC3H3_03790	COG1609	Transcriptional regulator
CSC3H3_03795	COG1739	Uncharacterized protein family UPF0029
CSC3H3_03810	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CSC3H3_03825	COG2442	InterPro IPR007367
CSC3H3_03835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CSC3H3_03840	COG0215	cysteine-tRNA ligase activity
CSC3H3_03870	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CSC3H3_03880	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CSC3H3_03885	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CSC3H3_03895	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CSC3H3_03900	COG2962	Rard protein
CSC3H3_03920	COG0583	DNA-binding transcription factor activity
CSC3H3_03930	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CSC3H3_03950	COG0643	Histidine kinase
CSC3H3_03950	COG2198	Histidine kinase
CSC3H3_03960	COG0745	RESPONSE REGULATOR receiver
CSC3H3_03985	COG1157	protein secretion by the type III secretion system
CSC3H3_04000	COG0861	Integral membrane protein TerC family
CSC3H3_04005	COG4134	Bacterial extracellular solute-binding protein
CSC3H3_04010	COG4135	transport system, permease component
CSC3H3_04015	COG4136	ATPase activity
CSC3H3_04020	COG3128	pkhd-type hydroxylase
CSC3H3_04035	COG0455	bacterial-type flagellum organization
CSC3H3_04040	COG0552	protein localization to endoplasmic reticulum
CSC3H3_04045	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CSC3H3_04050	COG2204	response regulator
CSC3H3_04055	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CSC3H3_04060	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSC3H3_04070	COG1766	The M ring may be actively involved in energy transduction
CSC3H3_04075	COG1749	Flagellar hook protein flgE
CSC3H3_04080	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CSC3H3_04095	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CSC3H3_04120	COG4786	Flagellar basal body rod
CSC3H3_04120	COG1256	bacterial-type flagellum assembly
CSC3H3_04135	COG1706	bacterial-type flagellum-dependent cell motility
CSC3H3_04145	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CSC3H3_04150	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CSC3H3_04155	COG1673	EVE domain
CSC3H3_04170	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CSC3H3_04175	COG4786	Flagellar basal body rod
CSC3H3_04180	COG4786	Flagellar basal body rod
CSC3H3_04210	COG0745	RESPONSE REGULATOR receiver
CSC3H3_04245	COG1338	Plays a role in the flagellum-specific transport system
CSC3H3_04260	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CSC3H3_04270	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CSC3H3_04275	COG1815	bacterial-type flagellum-dependent cell motility
CSC3H3_04280	COG1558	bacterial-type flagellum-dependent cell motility
CSC3H3_04285	COG1677	Flagellar hook-basal body complex protein FliE
CSC3H3_04290	COG1987	bacterial-type flagellum assembly
CSC3H3_04295	COG1684	flagellar biosynthetic protein fliR
CSC3H3_04300	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CSC3H3_04410	COG0583	DNA-binding transcription factor activity
CSC3H3_04420	COG1335	isochorismatase
CSC3H3_04430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSC3H3_04440	COG0438	transferase activity, transferring glycosyl groups
CSC3H3_04500	COG1643	Atp-dependent helicase
CSC3H3_04525	COG0583	DNA-binding transcription factor activity
CSC3H3_04535	COG2900	Belongs to the SlyX family
CSC3H3_04540	COG2084	Dehydrogenase
CSC3H3_04570	COG3386	PFAM SMP-30 Gluconolaconase
CSC3H3_04585	COG4178	(ABC) transporter
CSC3H3_04595	COG4774	siderophore transport
CSC3H3_04595	COG1629	transport
CSC3H3_04600	COG1199	ATP-dependent helicase activity
CSC3H3_04620	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSC3H3_04620	COG0596	Alpha beta hydrolase
CSC3H3_04625	COG2814	Major facilitator Superfamily
CSC3H3_04630	COG1309	transcriptional regulator
CSC3H3_04635	COG1238	metal cluster binding
CSC3H3_04645	COG1764	response to oxidative stress
CSC3H3_04655	COG1846	Transcriptional regulator
CSC3H3_04680	COG2200	EAL domain
CSC3H3_04680	COG2199	diguanylate cyclase activity
CSC3H3_04680	COG2202	Pas domain
CSC3H3_04700	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CSC3H3_04710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSC3H3_04720	COG1609	Transcriptional regulator
CSC3H3_04725	COG1840	ABC-type Fe3 transport system, periplasmic component
CSC3H3_04735	COG3842	ATPase activity
CSC3H3_04855	COG0625	glutathione transferase activity
CSC3H3_04860	COG0625	glutathione transferase activity
CSC3H3_04890	COG1733	regulation of RNA biosynthetic process
CSC3H3_04915	COG3842	ATPase activity
CSC3H3_04920	COG0395	ABC-type sugar transport system, permease component
CSC3H3_04935	COG0626	cystathionine gamma-synthase activity
CSC3H3_04940	COG2186	Transcriptional regulator
CSC3H3_04960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSC3H3_04965	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CSC3H3_04970	COG0028	Belongs to the TPP enzyme family
CSC3H3_04995	COG1309	transcriptional regulator
CSC3H3_05020	COG2391	methyltransferase activity
CSC3H3_05030	COG0513	Belongs to the DEAD box helicase family
CSC3H3_05035	COG1278	Cold shock
CSC3H3_05045	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CSC3H3_05050	COG0765	amino acid transport
CSC3H3_05070	COG1671	Belongs to the UPF0178 family
CSC3H3_05075	COG1012	belongs to the aldehyde dehydrogenase family
CSC3H3_05090	COG2130	NADP-dependent
CSC3H3_05095	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CSC3H3_05110	COG0523	cobalamin synthesis protein
CSC3H3_05115	COG1309	transcriptional regulator
CSC3H3_05125	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CSC3H3_05145	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CSC3H3_05145	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CSC3H3_05150	COG3180	Ammonia monooxygenase
CSC3H3_05180	COG3300	MHYT domain
CSC3H3_05180	COG5001	Diguanylate cyclase
CSC3H3_05190	COG0745	RESPONSE REGULATOR receiver
CSC3H3_05195	COG1366	Belongs to the anti-sigma-factor antagonist family
CSC3H3_05200	COG2204	response regulator
CSC3H3_05215	COG0784	Response regulator, receiver
CSC3H3_05215	COG5002	protein histidine kinase activity
CSC3H3_05225	COG0006	proline dipeptidase activity
CSC3H3_05240	COG1879	ABC-type sugar transport system periplasmic component
CSC3H3_05265	COG0772	Belongs to the SEDS family
CSC3H3_05270	COG0768	penicillin binding
CSC3H3_05290	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CSC3H3_05300	COG1280	lysine exporter protein (LysE YggA)
CSC3H3_05315	COG3706	GGDEF domain
CSC3H3_05320	COG1278	Cold shock
CSC3H3_05325	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CSC3H3_05330	COG5285	phytanoyl-CoA dioxygenase
CSC3H3_05370	COG0840	transmembrane signaling receptor activity
CSC3H3_05375	COG0840	transmembrane signaling receptor activity
CSC3H3_05385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CSC3H3_05385	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CSC3H3_05400	COG0519	Catalyzes the synthesis of GMP from XMP
CSC3H3_05435	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CSC3H3_05455	COG2814	Major facilitator Superfamily
CSC3H3_05470	COG2217	Heavy metal translocating P-type atpase
CSC3H3_05505	COG1012	belongs to the aldehyde dehydrogenase family
CSC3H3_05510	COG0596	Alpha beta hydrolase
CSC3H3_05515	COG0494	nUDIX hydrolase
CSC3H3_05520	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_05560	COG1653	transport
CSC3H3_05575	COG0366	Alpha amylase catalytic
CSC3H3_05580	COG3842	ATPase activity
CSC3H3_05585	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CSC3H3_05590	COG0363	glucosamine-6-phosphate deaminase activity
CSC3H3_05595	COG0129	dihydroxy-acid dehydratase activity
CSC3H3_05600	COG0837	glucose binding
CSC3H3_05605	COG0800	Aldolase
CSC3H3_05645	COG0573	inorganic phosphate transmembrane transporter activity
CSC3H3_05655	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CSC3H3_05660	COG0824	Thioesterase
CSC3H3_05660	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSC3H3_05665	COG3246	L-lysine catabolic process to acetate
CSC3H3_05670	COG4977	sequence-specific DNA binding
CSC3H3_05690	COG2719	SpoVR family
CSC3H3_05695	COG2718	Belongs to the UPF0229 family
CSC3H3_05700	COG2766	serine protein kinase
CSC3H3_05705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSC3H3_05735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CSC3H3_05750	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CSC3H3_05760	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CSC3H3_05770	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CSC3H3_05780	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CSC3H3_05785	COG0222	ribosome binding
CSC3H3_05790	COG0085	RNA polymerase activity
CSC3H3_05795	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CSC3H3_05815	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CSC3H3_05825	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CSC3H3_05830	COG0088	Forms part of the polypeptide exit tunnel
CSC3H3_05835	COG0089	rRNA binding
CSC3H3_05845	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CSC3H3_05850	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CSC3H3_05855	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CSC3H3_05860	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CSC3H3_05865	COG0255	Belongs to the universal ribosomal protein uL29 family
CSC3H3_05875	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CSC3H3_05880	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CSC3H3_05885	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CSC3H3_05895	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CSC3H3_05905	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CSC3H3_05915	COG1841	ribosomal large subunit assembly
CSC3H3_05920	COG0200	Binds to the 23S rRNA
CSC3H3_05925	COG0201	protein transport
CSC3H3_05930	COG0563	adenylate kinase activity
CSC3H3_05935	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CSC3H3_05940	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CSC3H3_05950	COG0203	ribosomal protein L17
CSC3H3_05955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSC3H3_05960	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CSC3H3_05965	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CSC3H3_05975	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CSC3H3_05980	COG0564	pseudouridine synthase activity
CSC3H3_05990	COG0546	phosphoglycolate phosphatase activity
CSC3H3_06010	COG0412	Dienelactone hydrolase
CSC3H3_06015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSC3H3_06040	COG5001	Diguanylate cyclase
CSC3H3_06045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CSC3H3_06055	COG4221	oxidoreductase activity
CSC3H3_06070	COG1254	Belongs to the acylphosphatase family
CSC3H3_06080	COG1595	DNA-templated transcription, initiation
CSC3H3_06090	COG4774	siderophore transport
CSC3H3_06095	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CSC3H3_06105	COG0277	FAD linked oxidase domain protein
CSC3H3_06110	COG0009	L-threonylcarbamoyladenylate synthase
CSC3H3_06125	COG0583	DNA-binding transcription factor activity
CSC3H3_06135	COG1355	regulation of microtubule-based process
CSC3H3_06155	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CSC3H3_06165	COG0840	transmembrane signaling receptor activity
CSC3H3_06170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CSC3H3_06175	COG2011	ABC-type metal ion transport system permease component
CSC3H3_06185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CSC3H3_06205	COG0488	(ABC) transporter
CSC3H3_06210	COG0105	UTP biosynthetic process
CSC3H3_06215	COG0840	transmembrane signaling receptor activity
CSC3H3_06230	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CSC3H3_06235	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CSC3H3_06245	COG0628	permease
CSC3H3_06250	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CSC3H3_06255	COG0189	ligase activity
CSC3H3_06255	COG4067	protein conserved in archaea
CSC3H3_06260	COG0189	ligase activity
CSC3H3_06270	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CSC3H3_06285	COG1733	regulation of RNA biosynthetic process
CSC3H3_06295	COG0583	DNA-binding transcription factor activity
CSC3H3_06305	COG0248	Ppx GppA phosphatase
CSC3H3_06310	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CSC3H3_06335	COG0640	Transcriptional regulator
CSC3H3_06340	COG0123	including yeast histone deacetylase and acetoin utilization protein
CSC3H3_06360	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CSC3H3_06375	COG1063	alcohol dehydrogenase
CSC3H3_06385	COG0318	PFAM AMP-dependent synthetase and ligase
CSC3H3_06415	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CSC3H3_06420	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CSC3H3_06430	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CSC3H3_06440	COG3210	domain, Protein
CSC3H3_06440	COG2911	Protein conserved in bacteria
CSC3H3_06445	COG0583	DNA-binding transcription factor activity
CSC3H3_06470	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CSC3H3_06475	COG1295	ribonuclease BN
CSC3H3_06485	COG0668	transmembrane transport
CSC3H3_06490	COG0427	acetyl-CoA hydrolase
CSC3H3_06500	COG0484	heat shock protein binding
CSC3H3_06515	COG0640	Transcriptional regulator
CSC3H3_06525	COG2135	peptidase activity
CSC3H3_06530	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_06545	COG0667	Aldo Keto reductase
CSC3H3_06565	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_06570	COG2207	Transcriptional regulator
CSC3H3_06575	COG0156	8-amino-7-oxononanoate synthase activity
CSC3H3_06585	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CSC3H3_06600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC3H3_06605	COG0601	transmembrane transport
CSC3H3_06610	COG0747	negative chemotaxis
CSC3H3_06615	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CSC3H3_06620	COG1024	Enoyl-CoA hydratase
CSC3H3_06630	COG2814	Major facilitator Superfamily
CSC3H3_06635	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CSC3H3_06640	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CSC3H3_06670	COG0656	L-ascorbic acid biosynthetic process
CSC3H3_06680	COG2070	2-Nitropropane dioxygenase
CSC3H3_06685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSC3H3_06695	COG1252	NADH dehydrogenase
CSC3H3_06710	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CSC3H3_06715	COG0583	DNA-binding transcription factor activity
CSC3H3_06720	COG3622	Belongs to the hyi family
CSC3H3_06730	COG2186	Transcriptional regulator
CSC3H3_06740	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CSC3H3_06770	COG3135	benzoate transporter
CSC3H3_06800	COG0483	inositol monophosphate 1-phosphatase activity
CSC3H3_06805	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CSC3H3_06815	COG0583	DNA-binding transcription factor activity
CSC3H3_06820	COG0352	thiamine-phosphate diphosphorylase activity
CSC3H3_06850	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CSC3H3_06860	COG1692	metallophosphoesterase
CSC3H3_06870	COG2207	Transcriptional regulator
CSC3H3_06875	COG1914	H( )-stimulated, divalent metal cation uptake system
CSC3H3_06905	COG0217	transcriptional regulatory protein
CSC3H3_06915	COG0632	four-way junction helicase activity
CSC3H3_06925	COG0824	Thioesterase
CSC3H3_06960	COG0037	tRNA processing
CSC3H3_06970	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CSC3H3_06980	COG2205	protein histidine kinase activity
CSC3H3_06990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CSC3H3_06995	COG0352	thiamine-phosphate diphosphorylase activity
CSC3H3_06995	COG0351	phosphomethylpyrimidine kinase
CSC3H3_07015	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CSC3H3_07025	COG0129	dihydroxy-acid dehydratase activity
CSC3H3_07030	COG0686	Belongs to the AlaDH PNT family
CSC3H3_07035	COG1522	sequence-specific DNA binding
CSC3H3_07055	COG1177	transmembrane transport
CSC3H3_07060	COG1176	ABC-type spermidine putrescine transport system, permease component I
CSC3H3_07065	COG3842	ATPase activity
CSC3H3_07070	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CSC3H3_07075	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CSC3H3_07080	COG0174	glutamine synthetase
CSC3H3_07090	COG4948	Mandelate Racemase Muconate Lactonizing
CSC3H3_07095	COG3706	GGDEF domain
CSC3H3_07120	COG4095	Psort location CytoplasmicMembrane, score
CSC3H3_07145	COG0842	Transport permease protein
CSC3H3_07150	COG0842	Transport permease protein
CSC3H3_07150	COG1129	ABC transporter
CSC3H3_07155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSC3H3_07160	COG0247	lactate metabolic process
CSC3H3_07160	COG0277	FAD linked oxidase domain protein
CSC3H3_07165	COG0583	DNA-binding transcription factor activity
CSC3H3_07175	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CSC3H3_07180	COG4221	oxidoreductase activity
CSC3H3_07185	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_07205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSC3H3_07210	COG2076	Multidrug Resistance protein
CSC3H3_07220	COG0583	DNA-binding transcription factor activity
CSC3H3_07240	COG0432	Pfam Uncharacterised protein family UPF0047
CSC3H3_07245	COG3384	dioxygenase
CSC3H3_07265	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSC3H3_07270	COG3761	NADH ubiquinone oxidoreductase 17.2 kD subunit
CSC3H3_07285	COG4765	Protein conserved in bacteria
CSC3H3_07290	COG0840	transmembrane signaling receptor activity
CSC3H3_07305	COG0534	Mate efflux family protein
CSC3H3_07310	COG1522	sequence-specific DNA binding
CSC3H3_07320	COG1959	2 iron, 2 sulfur cluster binding
CSC3H3_07325	COG0513	Belongs to the DEAD box helicase family
CSC3H3_07345	COG3038	cytochrome b561
CSC3H3_07350	COG2066	Belongs to the glutaminase family
CSC3H3_07355	COG0187	DNA topoisomerase II activity
CSC3H3_07360	COG1607	acyl-coa hydrolase
CSC3H3_07370	COG0583	DNA-binding transcription factor activity
CSC3H3_07380	COG4221	oxidoreductase activity
CSC3H3_07395	COG4608	Belongs to the ABC transporter superfamily
CSC3H3_07400	COG0444	Belongs to the ABC transporter superfamily
CSC3H3_07410	COG0601	transmembrane transport
CSC3H3_07460	COG0469	pyruvate kinase activity
CSC3H3_07485	COG0693	protein deglycase activity
CSC3H3_07495	COG0668	transmembrane transport
CSC3H3_07510	COG1832	CoA-binding protein
CSC3H3_07520	COG1280	lysine exporter protein (LysE YggA)
CSC3H3_07530	COG4774	siderophore transport
CSC3H3_07540	COG1024	Enoyl-CoA hydratase
CSC3H3_07555	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CSC3H3_07560	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CSC3H3_07575	COG2194	sulfuric ester hydrolase activity
CSC3H3_07590	COG0745	RESPONSE REGULATOR receiver
CSC3H3_07605	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CSC3H3_07610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSC3H3_07615	COG0697	spore germination
CSC3H3_07620	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CSC3H3_07630	COG1858	cytochrome C peroxidase
CSC3H3_07635	COG0640	Transcriptional regulator
CSC3H3_07645	COG2084	Dehydrogenase
CSC3H3_07650	COG3243	poly(R)-hydroxyalkanoic acid synthase
CSC3H3_07660	COG0436	Aminotransferase
CSC3H3_07670	COG1494	fructose-1,6-bisphosphatase
CSC3H3_07680	COG0443	Heat shock 70 kDa protein
CSC3H3_07685	COG1309	transcriptional regulator
CSC3H3_07690	COG1064	alcohol dehydrogenase
CSC3H3_07720	COG2271	Major facilitator Superfamily
CSC3H3_07740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CSC3H3_07760	COG1234	tRNA 3'-trailer cleavage
CSC3H3_07775	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CSC3H3_07780	COG0840	transmembrane signaling receptor activity
CSC3H3_07780	COG2972	Histidine kinase
CSC3H3_07800	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CSC3H3_07825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CSC3H3_07840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSC3H3_07845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSC3H3_07850	COG1116	anion transmembrane transporter activity
CSC3H3_07860	COG0583	DNA-binding transcription factor activity
CSC3H3_07865	COG0123	including yeast histone deacetylase and acetoin utilization protein
CSC3H3_07910	COG0523	cobalamin synthesis protein
CSC3H3_07920	COG0735	belongs to the Fur family
CSC3H3_07925	COG1121	(ABC) transporter
CSC3H3_07930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CSC3H3_07935	COG0626	cystathionine gamma-synthase activity
CSC3H3_07940	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CSC3H3_07945	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CSC3H3_07960	COG2897	thiosulfate sulfurtransferase activity
CSC3H3_07965	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CSC3H3_07985	COG1088	dTDP-glucose 4,6-dehydratase activity
CSC3H3_08000	COG1620	l-lactate permease
CSC3H3_08010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSC3H3_08025	COG2814	Major facilitator Superfamily
CSC3H3_08035	COG0494	nUDIX hydrolase
CSC3H3_08050	COG2195	Cleaves the N-terminal amino acid of tripeptides
CSC3H3_08120	COG0730	response to heat
CSC3H3_08125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSC3H3_08125	COG0425	Belongs to the sulfur carrier protein TusA family
CSC3H3_08130	COG2153	protein acetylation
CSC3H3_08165	COG1067	ATP-dependent peptidase activity
CSC3H3_08170	COG3327	negative regulation of DNA-templated transcription, initiation
CSC3H3_08180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSC3H3_08210	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_08220	COG3273	potassium ion transport
CSC3H3_08220	COG0471	metal ion transport
CSC3H3_08235	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CSC3H3_08255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CSC3H3_08260	COG0564	pseudouridine synthase activity
CSC3H3_08275	COG0438	transferase activity, transferring glycosyl groups
CSC3H3_08280	COG1846	Transcriptional regulator
CSC3H3_08300	COG1216	Glycosyl transferase, family 2
CSC3H3_08300	COG0438	transferase activity, transferring glycosyl groups
CSC3H3_08305	COG2226	methyltransferase
CSC3H3_08325	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CSC3H3_08360	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CSC3H3_08365	COG4175	Glycine betaine
CSC3H3_08365	COG3448	diguanylate cyclase activity
CSC3H3_08370	COG4176	ABC-type proline glycine betaine transport system permease component
CSC3H3_08385	COG2113	Glycine betaine
CSC3H3_08390	COG4176	ABC-type proline glycine betaine transport system permease component
CSC3H3_08395	COG4175	Glycine betaine
CSC3H3_08425	COG1840	ABC-type Fe3 transport system, periplasmic component
CSC3H3_08440	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CSC3H3_08455	COG0438	transferase activity, transferring glycosyl groups
CSC3H3_08465	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CSC3H3_08490	COG0747	negative chemotaxis
CSC3H3_08495	COG0601	transmembrane transport
CSC3H3_08500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC3H3_08510	COG2814	Major facilitator Superfamily
CSC3H3_08515	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CSC3H3_08515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CSC3H3_08520	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CSC3H3_08525	COG1393	Belongs to the ArsC family
CSC3H3_08530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CSC3H3_08535	COG0405	Gamma-glutamyltransferase
CSC3H3_08550	COG2363	Small membrane protein
CSC3H3_08555	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CSC3H3_08560	COG0793	Belongs to the peptidase S41A family
CSC3H3_08575	COG0557	exoribonuclease II activity
CSC3H3_08580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CSC3H3_08585	COG0758	DNA mediated transformation
CSC3H3_08590	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CSC3H3_08595	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CSC3H3_08615	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CSC3H3_08620	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CSC3H3_08630	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CSC3H3_08635	COG0431	NADPH-dependent FMN reductase
CSC3H3_08650	COG2223	nitrite transmembrane transporter activity
CSC3H3_08660	COG1435	thymidine kinase activity
CSC3H3_08675	COG2995	paraquat-inducible protein a
CSC3H3_08680	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CSC3H3_08680	COG3008	intermembrane lipid transfer
CSC3H3_08695	COG4977	sequence-specific DNA binding
CSC3H3_08700	COG2814	Major facilitator Superfamily
CSC3H3_08710	COG0625	glutathione transferase activity
CSC3H3_08750	COG0174	glutamine synthetase
CSC3H3_08760	COG1454	alcohol dehydrogenase
CSC3H3_08765	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CSC3H3_08765	COG0519	Catalyzes the synthesis of GMP from XMP
CSC3H3_08770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSC3H3_08775	COG0737	Belongs to the 5'-nucleotidase family
CSC3H3_08805	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CSC3H3_08810	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CSC3H3_08825	COG0559	Belongs to the binding-protein-dependent transport system permease family
CSC3H3_08835	COG0411	ABC transporter
CSC3H3_08860	COG1126	abc transporter atp-binding protein
CSC3H3_08865	COG0765	amino acid transport
CSC3H3_08870	COG4597	amino acid ABC transporter
CSC3H3_08875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSC3H3_08880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSC3H3_08885	COG0521	Mo-molybdopterin cofactor biosynthetic process
CSC3H3_08895	COG0840	transmembrane signaling receptor activity
CSC3H3_08900	COG4335	DNA alkylation repair
CSC3H3_08910	COG1414	Transcriptional regulator
CSC3H3_08915	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CSC3H3_08950	COG2814	Major facilitator Superfamily
CSC3H3_08975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CSC3H3_08980	COG3022	response to hydroperoxide
CSC3H3_08985	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CSC3H3_09010	COG0310	cobalt ion transport
CSC3H3_09030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSC3H3_09030	COG1042	CoA-binding domain protein
CSC3H3_09030	COG0045	succinate-CoA ligase (ADP-forming) activity
CSC3H3_09050	COG4989	oxidoreductase activity
CSC3H3_09070	COG0840	transmembrane signaling receptor activity
CSC3H3_09075	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CSC3H3_09080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSC3H3_09080	COG0425	Belongs to the sulfur carrier protein TusA family
CSC3H3_09085	COG1538	Outer membrane efflux protein
CSC3H3_09095	COG0525	valine-tRNA ligase activity
CSC3H3_09100	COG2329	Antibiotic biosynthesis monooxygenase
CSC3H3_09110	COG0512	Glutamine amidotransferase of anthranilate synthase
CSC3H3_09115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSC3H3_09125	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CSC3H3_09135	COG0316	Belongs to the HesB IscA family
CSC3H3_09150	COG1472	Belongs to the glycosyl hydrolase 3 family
CSC3H3_09155	COG1994	Peptidase M50
CSC3H3_09165	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CSC3H3_09170	COG3842	ATPase activity
CSC3H3_09175	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CSC3H3_09180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CSC3H3_09185	COG0805	protein transport
CSC3H3_09190	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CSC3H3_09205	COG4942	peptidase
CSC3H3_09205	COG1388	LysM domain
CSC3H3_09230	COG3737	Protein of unknown function (DUF498/DUF598)
CSC3H3_09235	COG0668	transmembrane transport
CSC3H3_09250	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CSC3H3_09260	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CSC3H3_09265	COG0191	fructose-bisphosphate aldolase activity
CSC3H3_09275	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CSC3H3_09280	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CSC3H3_09290	COG2971	BadF BadG BcrA BcrD
CSC3H3_09295	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CSC3H3_09300	COG1653	transport
CSC3H3_09305	COG1175	transmembrane transport
CSC3H3_09310	COG0395	ABC-type sugar transport system, permease component
CSC3H3_09315	COG3842	ATPase activity
CSC3H3_09325	COG3842	ATPase activity
CSC3H3_09330	COG1176	ABC-type spermidine putrescine transport system, permease component I
CSC3H3_09335	COG1177	transmembrane transport
CSC3H3_09340	COG1653	transport
CSC3H3_09350	COG0395	ABC-type sugar transport system, permease component
CSC3H3_09360	COG1956	GAF domain-containing protein
CSC3H3_09365	COG0629	single-stranded DNA binding
CSC3H3_09380	COG3012	SEC-C Motif Domain Protein
CSC3H3_09385	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CSC3H3_09415	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CSC3H3_09425	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CSC3H3_09440	COG0840	transmembrane signaling receptor activity
CSC3H3_09475	COG2951	lytic endotransglycosylase activity
CSC3H3_09485	COG1686	Belongs to the peptidase S11 family
CSC3H3_09490	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CSC3H3_09505	COG0084	hydrolase, TatD family'
CSC3H3_09510	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CSC3H3_09510	COG0321	lipoyl(octanoyl) transferase activity
CSC3H3_09570	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CSC3H3_09575	COG1917	Cupin 2, conserved barrel domain protein
CSC3H3_09580	COG0527	aspartate kinase activity
CSC3H3_09585	COG3956	TIGRFAM MazG family protein
CSC3H3_09595	COG0483	inositol monophosphate 1-phosphatase activity
CSC3H3_09600	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CSC3H3_09610	COG0546	phosphoglycolate phosphatase activity
CSC3H3_09615	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSC3H3_09620	COG0569	domain protein
CSC3H3_09625	COG2204	response regulator
CSC3H3_09660	COG2917	probably involved in intracellular septation
CSC3H3_09695	COG0416	fatty acid biosynthetic process
CSC3H3_09715	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CSC3H3_09720	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CSC3H3_09725	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CSC3H3_09730	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CSC3H3_09730	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CSC3H3_09740	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSC3H3_09740	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSC3H3_09745	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CSC3H3_09755	COG0698	ribose 5-phosphate isomerase
CSC3H3_09805	COG1024	Enoyl-CoA hydratase
CSC3H3_09810	COG1960	acyl-CoA dehydrogenase activity
CSC3H3_09830	COG0113	porphobilinogen synthase activity
CSC3H3_09835	COG1011	Hydrolase
CSC3H3_09845	COG0318	PFAM AMP-dependent synthetase and ligase
CSC3H3_09860	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CSC3H3_09865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSC3H3_09870	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CSC3H3_09875	COG1360	Flagellar Motor Protein
CSC3H3_09880	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CSC3H3_09885	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CSC3H3_09890	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CSC3H3_09900	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CSC3H3_09905	COG1381	Involved in DNA repair and RecF pathway recombination
CSC3H3_09915	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CSC3H3_09925	COG0681	Belongs to the peptidase S26 family
CSC3H3_09930	COG0736	holo-[acyl-carrier-protein] synthase activity
CSC3H3_09935	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CSC3H3_09955	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CSC3H3_09965	COG1573	uracil-dna glycosylase
CSC3H3_09970	COG0514	ATP-dependent DNA helicase (RecQ)
CSC3H3_09975	COG0386	Belongs to the glutathione peroxidase family
CSC3H3_09980	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CSC3H3_09985	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CSC3H3_09990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSC3H3_09995	COG0741	lytic transglycosylase activity
CSC3H3_10010	COG0739	heme binding
CSC3H3_10015	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CSC3H3_10020	COG1546	Belongs to the CinA family
CSC3H3_10020	COG1058	Belongs to the CinA family
CSC3H3_10025	COG2867	negative regulation of translational initiation
CSC3H3_10030	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CSC3H3_10035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSC3H3_10040	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSC3H3_10045	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSC3H3_10045	COG0022	dehydrogenase e1 component
CSC3H3_10050	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CSC3H3_10055	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CSC3H3_10060	COG0148	phosphopyruvate hydratase activity
CSC3H3_10080	COG0149	triose-phosphate isomerase activity
CSC3H3_10085	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CSC3H3_10090	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CSC3H3_10095	COG2861	carbohydrate metabolic process
CSC3H3_10115	COG0315	cyclic pyranopterin monophosphate synthase activity
CSC3H3_10125	COG0658	competence protein
CSC3H3_10125	COG2333	competence protein COMEC
CSC3H3_10135	COG0372	Belongs to the citrate synthase family
CSC3H3_10140	COG0346	lactoylglutathione lyase activity
CSC3H3_10145	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CSC3H3_10150	COG3494	Protein of unknown function (DUF1009)
CSC3H3_10155	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CSC3H3_10165	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CSC3H3_10180	COG0750	zinc metalloprotease
CSC3H3_10185	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CSC3H3_10190	COG0575	Belongs to the CDS family
CSC3H3_10195	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CSC3H3_10210	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CSC3H3_10215	COG0052	Belongs to the universal ribosomal protein uS2 family
CSC3H3_10220	COG0587	DNA-directed DNA polymerase activity
CSC3H3_10225	COG1136	(ABC) transporter
CSC3H3_10235	COG0442	prolyl-tRNA aminoacylation
CSC3H3_10285	COG0713	ATP synthesis coupled electron transport
CSC3H3_10300	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CSC3H3_10305	COG1034	ATP synthesis coupled electron transport
CSC3H3_10310	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CSC3H3_10315	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CSC3H3_10335	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSC3H3_10345	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSC3H3_10360	COG0776	regulation of translation
CSC3H3_10395	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CSC3H3_10395	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CSC3H3_10405	COG2205	protein histidine kinase activity
CSC3H3_10405	COG2202	Pas domain
CSC3H3_10420	COG2217	Heavy metal translocating P-type atpase
CSC3H3_10450	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CSC3H3_10465	COG0395	ABC-type sugar transport system, permease component
CSC3H3_10470	COG3842	ATPase activity
CSC3H3_10475	COG0840	transmembrane signaling receptor activity
CSC3H3_10475	COG5278	phosphoserine phosphatase activity
CSC3H3_10485	COG0745	RESPONSE REGULATOR receiver
CSC3H3_10495	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
CSC3H3_10520	COG0010	Belongs to the arginase family
CSC3H3_10525	COG1012	belongs to the aldehyde dehydrogenase family
CSC3H3_10530	COG1917	Cupin 2, conserved barrel domain protein
CSC3H3_10530	COG1396	sequence-specific DNA binding
CSC3H3_10535	COG0174	glutamine synthetase
CSC3H3_10545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CSC3H3_10550	COG2346	COG2346, Truncated hemoglobins
CSC3H3_10560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CSC3H3_10580	COG1309	transcriptional regulator
CSC3H3_10595	COG4175	Glycine betaine
CSC3H3_10595	COG0517	IMP dehydrogenase activity
CSC3H3_10605	COG0583	DNA-binding transcription factor activity
CSC3H3_10610	COG1176	ABC-type spermidine putrescine transport system, permease component I
CSC3H3_10615	COG1177	transmembrane transport
CSC3H3_10625	COG3842	ATPase activity
CSC3H3_10630	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CSC3H3_10635	COG3246	L-lysine catabolic process to acetate
CSC3H3_10650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CSC3H3_10655	COG0251	oxidation-reduction process
CSC3H3_10685	COG2423	ornithine cyclodeaminase activity
CSC3H3_10735	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CSC3H3_10740	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CSC3H3_10750	COG0251	oxidation-reduction process
CSC3H3_10770	COG0729	surface antigen
CSC3H3_10775	COG0189	ligase activity
CSC3H3_10780	COG0456	acetyltransferase
CSC3H3_10780	COG0454	-acetyltransferase
CSC3H3_10815	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CSC3H3_10820	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CSC3H3_10825	COG3485	protocatechuate 3,4-dioxygenase
CSC3H3_10830	COG3485	protocatechuate 3,4-dioxygenase
CSC3H3_10840	COG0596	Alpha beta hydrolase
CSC3H3_10845	COG0583	DNA-binding transcription factor activity
CSC3H3_10875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSC3H3_10910	COG2814	Major facilitator Superfamily
CSC3H3_10920	COG2375	cellular response to nickel ion
CSC3H3_10935	COG4172	Belongs to the ABC transporter superfamily
CSC3H3_10940	COG0747	negative chemotaxis
CSC3H3_10950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC3H3_10990	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CSC3H3_11005	COG0308	aminopeptidase N
CSC3H3_11035	COG0671	phosphoesterase, PA-phosphatase related
CSC3H3_11040	COG2205	protein histidine kinase activity
CSC3H3_11050	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CSC3H3_11055	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CSC3H3_11060	COG0840	transmembrane signaling receptor activity
CSC3H3_11065	COG4977	sequence-specific DNA binding
CSC3H3_11080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC3H3_11085	COG1120	ATPase activity
CSC3H3_11105	COG0848	biopolymer transport protein
CSC3H3_11110	COG0811	peptide transport
CSC3H3_11125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CSC3H3_11130	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CSC3H3_11135	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CSC3H3_11140	COG0697	spore germination
CSC3H3_11170	COG0418	dihydroorotase activity
CSC3H3_11185	COG0436	Aminotransferase
CSC3H3_11200	COG5001	Diguanylate cyclase
CSC3H3_11200	COG5002	protein histidine kinase activity
CSC3H3_11200	COG3447	MASE1 domain protein
CSC3H3_11210	COG1765	OsmC-like protein
CSC3H3_11235	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CSC3H3_11240	COG0457	Tetratricopeptide repeat
CSC3H3_11255	COG1917	Cupin 2, conserved barrel domain protein
CSC3H3_11255	COG2207	Transcriptional regulator
CSC3H3_11275	COG3287	FIST C domain
CSC3H3_11275	COG2200	EAL domain
CSC3H3_11275	COG2199	diguanylate cyclase activity
CSC3H3_11280	COG2824	Alkylphosphonate utilization operon protein PhnA
CSC3H3_11290	COG0583	DNA-binding transcription factor activity
CSC3H3_11315	COG0482	sulfurtransferase activity
CSC3H3_11320	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CSC3H3_11330	COG0633	Ferredoxin
CSC3H3_11335	COG0443	Heat shock 70 kDa protein
CSC3H3_11340	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CSC3H3_11345	COG0316	Belongs to the HesB IscA family
CSC3H3_11350	COG0822	iron-sulfur transferase activity
CSC3H3_11370	COG1045	serine acetyltransferase
CSC3H3_11375	COG2945	thiolester hydrolase activity
CSC3H3_11395	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CSC3H3_11400	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CSC3H3_11410	COG2833	Protein of unknown function (DUF455)
CSC3H3_11420	COG0583	DNA-binding transcription factor activity
CSC3H3_11430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CSC3H3_11455	COG1566	PFAM secretion protein HlyD family protein
CSC3H3_11475	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CSC3H3_11480	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSC3H3_11490	COG1530	ribonuclease E activity
CSC3H3_11515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CSC3H3_11515	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CSC3H3_11525	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CSC3H3_11530	COG0511	ligase activity, forming carbon-carbon bonds
CSC3H3_11535	COG0439	Biotin carboxylase
CSC3H3_11555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CSC3H3_11565	COG0840	transmembrane signaling receptor activity
CSC3H3_11585	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CSC3H3_11605	COG1686	Belongs to the peptidase S11 family
CSC3H3_11615	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CSC3H3_11620	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CSC3H3_11635	COG1192	Involved in chromosome partitioning
CSC3H3_11645	COG0579	oxidoreductase
CSC3H3_11685	COG3655	Transcriptional regulator
CSC3H3_11705	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CSC3H3_11710	COG1024	Enoyl-CoA hydratase
CSC3H3_11735	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CSC3H3_11750	COG0583	DNA-binding transcription factor activity
CSC3H3_11760	COG2326	polyphosphate kinase activity
CSC3H3_11765	COG2084	Dehydrogenase
CSC3H3_11770	COG0793	Belongs to the peptidase S41A family
CSC3H3_11775	COG1960	acyl-CoA dehydrogenase activity
CSC3H3_11780	COG0795	lipopolysaccharide-transporting ATPase activity
CSC3H3_11790	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CSC3H3_11795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CSC3H3_11805	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CSC3H3_11810	COG0194	GDP metabolic process
CSC3H3_11815	COG1561	YicC-like family, N-terminal region
CSC3H3_11825	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CSC3H3_11830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CSC3H3_11845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CSC3H3_11860	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CSC3H3_11870	COG0359	binds to the 23S rRNA
CSC3H3_11875	COG0305	Participates in initiation and elongation during chromosome replication
CSC3H3_11880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CSC3H3_11885	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CSC3H3_11905	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CSC3H3_11910	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_11920	COG1116	anion transmembrane transporter activity
CSC3H3_11925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSC3H3_11940	COG1160	GTP binding
CSC3H3_11970	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSC3H3_11975	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CSC3H3_11975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSC3H3_11980	COG1476	TRANSCRIPTIONal
CSC3H3_12000	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSC3H3_12005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CSC3H3_12015	COG1902	pentaerythritol trinitrate reductase activity
CSC3H3_12055	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CSC3H3_12060	COG3152	Membrane
CSC3H3_12085	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CSC3H3_12090	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CSC3H3_12095	COG0546	phosphoglycolate phosphatase activity
CSC3H3_12115	COG4214	carbohydrate transport
CSC3H3_12125	COG4213	ABC transporter substrate-binding protein
CSC3H3_12135	COG0237	dephospho-CoA kinase activity
CSC3H3_12140	COG1525	nuclease
CSC3H3_12150	COG0406	alpha-ribazole phosphatase activity
CSC3H3_12170	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CSC3H3_12200	COG2205	protein histidine kinase activity
CSC3H3_12205	COG0745	RESPONSE REGULATOR receiver
CSC3H3_12220	COG1283	sodium-dependent phosphate transmembrane transporter activity
CSC3H3_12230	COG0367	asparagine synthase
CSC3H3_12235	COG1522	sequence-specific DNA binding
CSC3H3_12240	COG3284	Transcriptional regulator
CSC3H3_12245	COG1012	belongs to the aldehyde dehydrogenase family
CSC3H3_12255	COG2855	membrane
CSC3H3_12265	COG0583	DNA-binding transcription factor activity
CSC3H3_12270	COG1271	oxidase subunit
CSC3H3_12275	COG1294	oxidase, subunit
CSC3H3_12290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSC3H3_12305	COG1012	belongs to the aldehyde dehydrogenase family
CSC3H3_12310	COG3724	N-succinylarginine dihydrolase activity
CSC3H3_12315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CSC3H3_12320	COG1522	sequence-specific DNA binding
CSC3H3_12325	COG0175	sulfate reduction
CSC3H3_12345	COG0436	Aminotransferase
CSC3H3_12350	COG0659	secondary active sulfate transmembrane transporter activity
CSC3H3_12355	COG3842	ATPase activity
CSC3H3_12360	COG1176	ABC-type spermidine putrescine transport system, permease component I
CSC3H3_12365	COG1177	transmembrane transport
CSC3H3_12385	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CSC3H3_12410	COG2827	Endonuclease containing a URI domain
CSC3H3_12415	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_12420	COG0800	Aldolase
CSC3H3_12425	COG3734	2-keto-3-deoxy-galactonokinase
CSC3H3_12430	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CSC3H3_12435	COG1309	transcriptional regulator
CSC3H3_12455	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CSC3H3_12460	COG1845	cytochrome c oxidase, subunit III
CSC3H3_12465	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CSC3H3_12470	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CSC3H3_12475	COG0477	Major facilitator Superfamily
CSC3H3_12480	COG0840	transmembrane signaling receptor activity
CSC3H3_12485	COG1959	2 iron, 2 sulfur cluster binding
CSC3H3_12495	COG0300	oxidoreductase activity
CSC3H3_12535	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CSC3H3_12545	COG1215	transferase activity, transferring glycosyl groups
CSC3H3_12550	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_12555	COG0583	DNA-binding transcription factor activity
CSC3H3_12560	COG0366	Alpha amylase catalytic
CSC3H3_12570	COG1414	Transcriptional regulator
CSC3H3_12575	COG1072	(Pantothenic acid kinase))
CSC3H3_12610	COG2186	Transcriptional regulator
CSC3H3_12615	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC3H3_12620	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC3H3_12625	COG1129	ABC transporter
CSC3H3_12630	COG1879	ABC-type sugar transport system periplasmic component
CSC3H3_12635	COG2017	converts alpha-aldose to the beta-anomer
CSC3H3_12650	COG3220	belongs to the UPF0276 family
CSC3H3_12660	COG0667	Aldo Keto reductase
CSC3H3_12665	COG2223	nitrite transmembrane transporter activity
CSC3H3_12680	COG2010	Cytochrome c
CSC3H3_12680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CSC3H3_12700	COG1840	ABC-type Fe3 transport system, periplasmic component
CSC3H3_12705	COG3842	ATPase activity
CSC3H3_12710	COG4208	sulfate ABC transporter
CSC3H3_12885	COG1132	(ABC) transporter
CSC3H3_12895	COG0254	rRNA binding
CSC3H3_12915	COG0604	alcohol dehydrogenase
CSC3H3_12930	COG1349	DNA-binding transcription factor activity
CSC3H3_12965	COG1309	transcriptional regulator
CSC3H3_12985	COG2807	transmembrane transport
CSC3H3_13010	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CSC3H3_13015	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CSC3H3_13030	COG0242	peptide deformylase activity
CSC3H3_13035	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CSC3H3_13055	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CSC3H3_13060	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CSC3H3_13065	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CSC3H3_13075	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CSC3H3_13085	COG1022	Amp-dependent synthetase and ligase
CSC3H3_13110	COG0542	response to heat
CSC3H3_13135	COG2890	protein-(glutamine-N5) methyltransferase activity
CSC3H3_13140	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CSC3H3_13145	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CSC3H3_13150	COG0124	histidyl-tRNA synthetase
CSC3H3_13155	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CSC3H3_13160	COG1426	Protein conserved in bacteria
CSC3H3_13175	COG0527	aspartate kinase activity
CSC3H3_13190	COG1881	PFAM PEBP family protein
CSC3H3_13195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CSC3H3_13205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSC3H3_13210	COG2199	diguanylate cyclase activity
CSC3H3_13230	COG1136	(ABC) transporter
CSC3H3_13240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CSC3H3_13245	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CSC3H3_13260	COG0625	glutathione transferase activity
CSC3H3_13265	COG1017	nitric oxide dioxygenase activity
CSC3H3_13265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSC3H3_13270	COG2226	methyltransferase
CSC3H3_13280	COG1489	DNA binding
CSC3H3_13285	COG0024	Methionine aminopeptidase
CSC3H3_13290	COG2814	Major facilitator Superfamily
CSC3H3_13295	COG1335	isochorismatase
CSC3H3_13305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CSC3H3_13315	COG2003	Belongs to the UPF0758 family
CSC3H3_13320	COG0346	lactoylglutathione lyase activity
CSC3H3_13330	COG1846	Transcriptional regulator
CSC3H3_13335	COG0667	Aldo Keto reductase
CSC3H3_13365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CSC3H3_13370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CSC3H3_13390	COG2986	histidine ammonia-lyase
CSC3H3_13420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CSC3H3_13430	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_13435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CSC3H3_13445	COG2207	Transcriptional regulator
CSC3H3_13475	COG0688	phosphatidylethanolamine metabolic process
CSC3H3_13510	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CSC3H3_13530	COG0583	DNA-binding transcription factor activity
CSC3H3_13565	COG0538	isocitrate dehydrogenase activity
CSC3H3_13570	COG4221	oxidoreductase activity
CSC3H3_13575	COG2207	Transcriptional regulator
CSC3H3_13585	COG1595	DNA-templated transcription, initiation
CSC3H3_13595	COG1741	Belongs to the pirin family
CSC3H3_13600	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CSC3H3_13605	COG0655	NAD(P)H dehydrogenase (quinone) activity
CSC3H3_13610	COG0584	glycerophosphoryl diester phosphodiesterase
CSC3H3_13615	COG4187	Peptidase family M20/M25/M40
CSC3H3_13625	COG1846	Transcriptional regulator
CSC3H3_13635	COG0542	response to heat
CSC3H3_13640	COG0583	DNA-binding transcription factor activity
CSC3H3_13645	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_13650	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_13685	COG4325	translation initiation factor activity
CSC3H3_13690	COG1522	sequence-specific DNA binding
CSC3H3_13725	COG5487	UPF0391 membrane protein
CSC3H3_13740	COG0602	queuosine metabolic process
CSC3H3_13745	COG0720	synthase
CSC3H3_13755	COG2226	methyltransferase
CSC3H3_13770	COG0601	transmembrane transport
CSC3H3_13775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC3H3_13780	COG0444	Belongs to the ABC transporter superfamily
CSC3H3_13790	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CSC3H3_13805	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CSC3H3_13810	COG0583	DNA-binding transcription factor activity
CSC3H3_13820	COG0504	CTP synthase activity
CSC3H3_13840	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CSC3H3_13845	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CSC3H3_13850	COG0047	phosphoribosylformylglycinamidine synthase activity
CSC3H3_13855	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CSC3H3_13860	COG0583	DNA-binding transcription factor activity
CSC3H3_13865	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_13870	COG0489	protein tyrosine kinase activity
CSC3H3_13875	COG0330	HflC and HflK could
CSC3H3_13880	COG0330	HflC and HflK could
CSC3H3_13890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSC3H3_13895	COG0560	Phosphoserine phosphatase
CSC3H3_13895	COG3830	Belongs to the UPF0237 family
CSC3H3_13910	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CSC3H3_13915	COG0028	Belongs to the TPP enzyme family
CSC3H3_13920	COG0440	acetolactate synthase activity
CSC3H3_13925	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CSC3H3_13930	COG2814	Major facilitator Superfamily
CSC3H3_13935	COG0583	DNA-binding transcription factor activity
CSC3H3_13955	COG0415	Belongs to the DNA photolyase family
CSC3H3_13960	COG3025	triphosphatase activity
CSC3H3_13970	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CSC3H3_13975	COG1530	ribonuclease E activity
CSC3H3_14000	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CSC3H3_14010	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CSC3H3_14060	COG2197	response regulator
CSC3H3_14070	COG0604	alcohol dehydrogenase
CSC3H3_14075	COG3339	Conserved Protein
CSC3H3_14105	COG0354	folic acid binding
CSC3H3_14110	COG0574	Belongs to the PEP-utilizing enzyme family
CSC3H3_14110	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CSC3H3_14120	COG0752	glycyl-tRNA synthetase alpha subunit
CSC3H3_14135	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CSC3H3_14145	COG0142	geranyltranstransferase activity
CSC3H3_14170	COG3474	cytochrome
CSC3H3_14180	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CSC3H3_14210	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CSC3H3_14215	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CSC3H3_14220	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_14225	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CSC3H3_14230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CSC3H3_14255	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CSC3H3_14260	COG0343	queuine tRNA-ribosyltransferase activity
CSC3H3_14265	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CSC3H3_14270	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CSC3H3_14275	COG0306	phosphate transporter
CSC3H3_14290	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_14295	COG1733	regulation of RNA biosynthetic process
CSC3H3_14300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CSC3H3_14330	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CSC3H3_14350	COG0277	FAD linked oxidase domain protein
CSC3H3_14355	COG3119	arylsulfatase activity
CSC3H3_14370	COG2378	regulation of single-species biofilm formation
CSC3H3_14380	COG0559	Belongs to the binding-protein-dependent transport system permease family
CSC3H3_14385	COG0069	glutamate synthase activity
CSC3H3_14425	COG0840	transmembrane signaling receptor activity
CSC3H3_14430	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CSC3H3_14445	COG3023	N-Acetylmuramoyl-L-alanine amidase
CSC3H3_14465	COG1335	isochorismatase
CSC3H3_14470	COG2207	Transcriptional regulator
CSC3H3_14490	COG2001	Belongs to the MraZ family
CSC3H3_14495	COG0275	rRNA processing
CSC3H3_14510	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CSC3H3_14540	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CSC3H3_14550	COG1181	Belongs to the D-alanine--D-alanine ligase family
CSC3H3_14555	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CSC3H3_14585	COG1653	transport
CSC3H3_14590	COG0849	cell division
CSC3H3_14605	COG0583	DNA-binding transcription factor activity
CSC3H3_14610	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CSC3H3_14630	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CSC3H3_14635	COG0497	DNA recombination
CSC3H3_14640	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CSC3H3_14655	COG0697	spore germination
CSC3H3_14665	COG0667	Aldo Keto reductase
CSC3H3_14670	COG0583	DNA-binding transcription factor activity
CSC3H3_14715	COG0006	proline dipeptidase activity
CSC3H3_14725	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_14730	COG2264	protein methyltransferase activity
CSC3H3_14735	COG0210	DNA helicase
CSC3H3_14745	COG3188	usher protein
CSC3H3_14770	COG2814	Major facilitator Superfamily
CSC3H3_14785	COG0745	RESPONSE REGULATOR receiver
CSC3H3_14795	COG0784	Response regulator, receiver
CSC3H3_14795	COG4191	Histidine kinase
CSC3H3_14800	COG2201	protein-glutamate methylesterase activity
CSC3H3_14810	COG1410	methionine synthase
CSC3H3_14810	COG0646	methionine synthase
CSC3H3_14820	COG2226	methyltransferase
CSC3H3_14825	COG2853	Lipoprotein
CSC3H3_14845	COG0488	(ABC) transporter
CSC3H3_14860	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSC3H3_14865	COG0516	GMP reductase activity
CSC3H3_14865	COG0517	IMP dehydrogenase activity
CSC3H3_14880	COG1063	alcohol dehydrogenase
CSC3H3_14890	COG0725	ABC transporter, periplasmic molybdate-binding protein
CSC3H3_14895	COG4149	molybdate abc transporter
CSC3H3_14900	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CSC3H3_14910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CSC3H3_14915	COG0583	DNA-binding transcription factor activity
CSC3H3_14940	COG3842	ATPase activity
CSC3H3_14945	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CSC3H3_14970	COG1349	DNA-binding transcription factor activity
CSC3H3_14980	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_15015	COG0745	RESPONSE REGULATOR receiver
CSC3H3_15020	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CSC3H3_15040	COG0583	DNA-binding transcription factor activity
CSC3H3_15055	COG4774	siderophore transport
CSC3H3_15060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSC3H3_15065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC3H3_15070	COG1120	ATPase activity
CSC3H3_15075	COG1132	(ABC) transporter
CSC3H3_15080	COG1473	amidohydrolase
CSC3H3_15095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CSC3H3_15115	COG0505	Belongs to the CarA family
CSC3H3_15120	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CSC3H3_15125	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CSC3H3_15130	COG1522	sequence-specific DNA binding
CSC3H3_15135	COG0492	ferredoxin-NADP+ reductase activity
CSC3H3_15140	COG0583	DNA-binding transcription factor activity
CSC3H3_15145	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CSC3H3_15155	COG2932	Transcriptional regulator
CSC3H3_15165	COG1475	DNA binding
CSC3H3_15175	COG2801	Transposase and inactivated derivatives
CSC3H3_15180	COG2842	Transposition protein
CSC3H3_15270	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CSC3H3_15290	COG4373	Mu-like prophage FluMu protein gp28
CSC3H3_15295	COG4383	Mu-like prophage protein gp29
CSC3H3_15310	COG4388	Caudovirus prohead serine protease
CSC3H3_15410	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CSC3H3_15415	COG0783	Belongs to the Dps family
CSC3H3_15420	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CSC3H3_15430	COG0556	nucleotide-excision repair
CSC3H3_15445	COG0367	asparagine synthase
CSC3H3_15450	COG0463	Glycosyl transferase, family 2
CSC3H3_15460	COG0450	alkyl hydroperoxide reductase
CSC3H3_15465	COG0583	DNA-binding transcription factor activity
CSC3H3_15485	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CSC3H3_15485	COG0519	Catalyzes the synthesis of GMP from XMP
CSC3H3_15490	COG0012	GTP binding
CSC3H3_15500	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CSC3H3_15505	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CSC3H3_15560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSC3H3_15590	COG0745	RESPONSE REGULATOR receiver
CSC3H3_15595	COG1846	Transcriptional regulator
CSC3H3_15600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSC3H3_15605	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSC3H3_15610	COG2207	Transcriptional regulator
CSC3H3_15615	COG0372	Belongs to the citrate synthase family
CSC3H3_15620	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CSC3H3_15625	COG0408	coproporphyrinogen oxidase activity
CSC3H3_15630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CSC3H3_15650	COG1280	lysine exporter protein (LysE YggA)
CSC3H3_15665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSC3H3_15690	COG0572	uridine kinase
CSC3H3_15700	COG1335	isochorismatase
CSC3H3_15710	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CSC3H3_15715	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CSC3H3_15720	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CSC3H3_15735	COG0789	Transcriptional regulator
CSC3H3_15745	COG2376	Dihydroxyacetone kinase
CSC3H3_15750	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CSC3H3_15765	COG3181	Tripartite tricarboxylate transporter family receptor
CSC3H3_15785	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CSC3H3_15790	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CSC3H3_15860	COG1321	iron dependent repressor
CSC3H3_15875	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CSC3H3_15880	COG1360	Flagellar Motor Protein
CSC3H3_15890	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CSC3H3_15915	COG1473	amidohydrolase
CSC3H3_15925	COG0612	Peptidase, M16
CSC3H3_15930	COG0612	Peptidase, M16
CSC3H3_15950	COG0196	riboflavin kinase activity
CSC3H3_15955	COG2030	dehydratase
CSC3H3_15960	COG2226	methyltransferase
CSC3H3_16010	COG0737	Belongs to the 5'-nucleotidase family
CSC3H3_16020	COG2207	Transcriptional regulator
CSC3H3_16040	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CSC3H3_16045	COG1940	carbohydrate kinase activity
CSC3H3_16050	COG1069	ribulokinase activity
CSC3H3_16055	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_16075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CSC3H3_16080	COG1960	acyl-CoA dehydrogenase activity
CSC3H3_16085	COG0583	DNA-binding transcription factor activity
CSC3H3_16115	COG0583	DNA-binding transcription factor activity
CSC3H3_16145	COG0501	Belongs to the peptidase M48B family
CSC3H3_16180	COG4251	negative regulation of phosphorylation
CSC3H3_16190	COG0583	DNA-binding transcription factor activity
CSC3H3_16195	COG2814	Major facilitator Superfamily
CSC3H3_16200	COG2832	Protein of unknown function (DUF454)
CSC3H3_16220	COG0583	DNA-binding transcription factor activity
CSC3H3_16235	COG1320	monovalent cation:proton antiporter activity
CSC3H3_16240	COG2212	antiporter activity
CSC3H3_16245	COG1863	multisubunit Na H antiporter MnhE subunit
CSC3H3_16250	COG0651	ATP synthesis coupled electron transport
CSC3H3_16255	COG1006	Multisubunit Na H antiporter MnhC subunit
CSC3H3_16260	COG2111	Na H antiporter
CSC3H3_16260	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CSC3H3_16265	COG2814	Major facilitator Superfamily
CSC3H3_16270	COG0626	cystathionine gamma-synthase activity
CSC3H3_16275	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CSC3H3_16280	COG0410	ABC transporter
CSC3H3_16315	COG3300	MHYT domain
CSC3H3_16315	COG5001	Diguanylate cyclase
CSC3H3_16320	COG0733	neurotransmitter:sodium symporter activity
CSC3H3_16335	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CSC3H3_16340	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CSC3H3_16350	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CSC3H3_16355	COG1138	Cytochrome C-type biogenesis protein
CSC3H3_16360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CSC3H3_16365	COG3088	subunit of a heme lyase
CSC3H3_16370	COG3088	subunit of a heme lyase
CSC3H3_16370	COG4235	cytochrome complex assembly
CSC3H3_16395	COG1012	belongs to the aldehyde dehydrogenase family
CSC3H3_16420	COG1473	amidohydrolase
CSC3H3_16445	COG3706	GGDEF domain
CSC3H3_16445	COG0745	RESPONSE REGULATOR receiver
CSC3H3_16450	COG3142	Participates in the control of copper homeostasis
CSC3H3_16455	COG1940	carbohydrate kinase activity
CSC3H3_16465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSC3H3_16470	COG1446	asparaginase
CSC3H3_16475	COG1126	abc transporter atp-binding protein
CSC3H3_16480	COG0765	amino acid transport
CSC3H3_16485	COG0765	amino acid transport
CSC3H3_16500	COG0612	Peptidase, M16
CSC3H3_16510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CSC3H3_16515	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CSC3H3_16530	COG1845	cytochrome c oxidase, subunit III
CSC3H3_16540	COG0109	protoheme IX farnesyltransferase activity
CSC3H3_16545	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CSC3H3_16550	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CSC3H3_16585	COG2814	Major facilitator Superfamily
CSC3H3_16590	COG0583	DNA-binding transcription factor activity
CSC3H3_16595	COG1309	transcriptional regulator
CSC3H3_16605	COG1678	Uncharacterized ACR, COG1678
CSC3H3_16615	COG0678	peroxiredoxin activity
CSC3H3_16630	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CSC3H3_16635	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CSC3H3_16640	COG0509	glycine decarboxylation via glycine cleavage system
CSC3H3_16645	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CSC3H3_16655	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CSC3H3_16665	COG0328	RNA-DNA hybrid ribonuclease activity
CSC3H3_16710	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CSC3H3_16740	COG2096	Adenosyltransferase
CSC3H3_16755	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSC3H3_16760	COG1070	Carbohydrate kinase
CSC3H3_16765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSC3H3_16770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CSC3H3_16775	COG0165	Argininosuccinate lyase
CSC3H3_16780	COG0019	diaminopimelate decarboxylase activity
CSC3H3_16795	COG2884	Cell division ATP-binding protein ftsE
CSC3H3_16830	COG0287	Prephenate dehydrogenase
CSC3H3_16845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CSC3H3_16850	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CSC3H3_16850	COG2813	Specifically methylates the guanine in position
CSC3H3_16865	COG0314	molybdopterin synthase activity
CSC3H3_16870	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CSC3H3_16875	COG2233	PERMEase
CSC3H3_16910	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_16930	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CSC3H3_16950	COG0745	RESPONSE REGULATOR receiver
CSC3H3_16955	COG0704	Plays a role in the regulation of phosphate uptake
CSC3H3_16965	COG0581	inorganic phosphate transmembrane transporter activity
CSC3H3_16970	COG0573	inorganic phosphate transmembrane transporter activity
CSC3H3_16975	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CSC3H3_16985	COG0247	lactate metabolic process
CSC3H3_16990	COG0277	FAD linked oxidase domain protein
CSC3H3_16995	COG0277	FAD linked oxidase domain protein
CSC3H3_17000	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CSC3H3_17015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CSC3H3_17035	COG0747	negative chemotaxis
CSC3H3_17065	COG1968	undecaprenyl-diphosphatase activity
CSC3H3_17070	COG0640	Transcriptional regulator
CSC3H3_17080	COG0740	serine-type endopeptidase activity
CSC3H3_17110	COG0778	Nitroreductase
CSC3H3_17125	COG1546	Belongs to the CinA family
CSC3H3_17125	COG1058	Belongs to the CinA family
CSC3H3_17140	COG0159	tryptophan synthase activity
CSC3H3_17170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CSC3H3_17175	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CSC3H3_17185	COG1639	'signal transduction protein
CSC3H3_17200	COG1742	UPF0060 membrane protein
CSC3H3_17215	COG1522	sequence-specific DNA binding
CSC3H3_17220	COG3186	Phenylalanine-4-hydroxylase
CSC3H3_17240	COG2814	Major facilitator Superfamily
CSC3H3_17260	COG1703	isobutyryl-CoA mutase activity
CSC3H3_17270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CSC3H3_17310	COG0501	Belongs to the peptidase M48B family
CSC3H3_17315	COG2095	MarC family integral membrane protein
CSC3H3_17345	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_17350	COG5642	Protein of unknown function (DUF2384)
CSC3H3_17360	COG0583	DNA-binding transcription factor activity
CSC3H3_17365	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CSC3H3_17375	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CSC3H3_17380	COG1122	ATPase activity
CSC3H3_17385	COG1268	BioY protein
CSC3H3_17400	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CSC3H3_17405	COG0830	nickel cation binding
CSC3H3_17410	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CSC3H3_17415	COG0804	urea catabolic process
CSC3H3_17420	COG0832	Belongs to the urease beta subunit family
CSC3H3_17425	COG0831	urea catabolic process
CSC3H3_17430	COG0829	nickel cation binding
CSC3H3_17435	COG0410	ABC transporter
CSC3H3_17440	COG0411	ABC transporter
CSC3H3_17450	COG0559	Belongs to the binding-protein-dependent transport system permease family
CSC3H3_17480	COG0583	DNA-binding transcription factor activity
CSC3H3_17490	COG1346	cytolysis
CSC3H3_17495	COG1380	Effector of murein hydrolase LrgA
CSC3H3_17500	COG0583	DNA-binding transcription factor activity
CSC3H3_17510	COG0840	transmembrane signaling receptor activity
CSC3H3_17515	COG0840	transmembrane signaling receptor activity
CSC3H3_17545	COG0590	tRNA wobble adenosine to inosine editing
CSC3H3_17555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CSC3H3_17560	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CSC3H3_17580	COG4266	Belongs to the allantoicase family
CSC3H3_17585	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CSC3H3_17600	COG1733	regulation of RNA biosynthetic process
CSC3H3_17610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CSC3H3_17620	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CSC3H3_17630	COG2030	dehydratase
CSC3H3_17635	COG2301	Belongs to the HpcH HpaI aldolase family
CSC3H3_17640	COG2885	chlorophyll binding
CSC3H3_17655	COG1566	PFAM secretion protein HlyD family protein
CSC3H3_17675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CSC3H3_17710	COG1842	Phage shock protein A
CSC3H3_17715	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CSC3H3_17730	COG1960	acyl-CoA dehydrogenase activity
CSC3H3_17735	COG0288	reversible hydration of carbon dioxide
CSC3H3_17740	COG0183	Belongs to the thiolase family
CSC3H3_17745	COG1960	acyl-CoA dehydrogenase activity
CSC3H3_17765	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CSC3H3_17775	COG0513	Belongs to the DEAD box helicase family
CSC3H3_17790	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CSC3H3_17795	COG3474	cytochrome
CSC3H3_17825	COG4221	oxidoreductase activity
CSC3H3_17845	COG1522	sequence-specific DNA binding
CSC3H3_17865	COG2154	pterin-4-alpha-carbinolamine dehydratase
CSC3H3_17880	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CSC3H3_17900	COG4172	Belongs to the ABC transporter superfamily
CSC3H3_17905	COG4239	(ABC) transporter, permease
CSC3H3_17910	COG4174	ABC transporter (Permease)
CSC3H3_17915	COG4166	transmembrane transport
CSC3H3_17920	COG0583	DNA-binding transcription factor activity
CSC3H3_17975	COG0693	protein deglycase activity
CSC3H3_17980	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CSC3H3_17985	COG1741	Belongs to the pirin family
CSC3H3_17990	COG0667	Aldo Keto reductase
CSC3H3_18020	COG4181	ATPase activity
CSC3H3_18025	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CSC3H3_18030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSC3H3_18040	COG0670	Belongs to the BI1 family
CSC3H3_18050	COG0501	Belongs to the peptidase M48B family
CSC3H3_18055	COG2902	Dehydrogenase
CSC3H3_18060	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CSC3H3_18070	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_18075	COG5001	Diguanylate cyclase
CSC3H3_18095	COG3118	belongs to the thioredoxin family
CSC3H3_18105	COG2835	tetraacyldisaccharide 4'-kinase activity
CSC3H3_18115	COG3047	cAMP biosynthetic process
CSC3H3_18120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSC3H3_18125	COG0347	Belongs to the P(II) protein family
CSC3H3_18130	COG0004	ammonium transporteR
CSC3H3_18135	COG0004	ammonium transporteR
CSC3H3_18145	COG1674	ftsk spoiiie
CSC3H3_18150	COG3069	C4-dicarboxylate transmembrane transporter activity
CSC3H3_18155	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CSC3H3_18165	COG0840	transmembrane signaling receptor activity
CSC3H3_18170	COG0840	transmembrane signaling receptor activity
CSC3H3_18185	COG1074	ATP-dependent DNA helicase activity
CSC3H3_18190	COG2887	Belongs to the helicase family. UvrD subfamily
CSC3H3_18200	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CSC3H3_18210	COG0802	atpase or kinase
CSC3H3_18225	COG4702	Belongs to the UPF0303 family
CSC3H3_18235	COG4251	negative regulation of phosphorylation
CSC3H3_18260	COG0072	phenylalanine-tRNA ligase activity
CSC3H3_18265	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CSC3H3_18270	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CSC3H3_18275	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CSC3H3_18280	COG0745	RESPONSE REGULATOR receiver
CSC3H3_18285	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CSC3H3_18290	COG0859	PFAM glycosyl transferase family 9
CSC3H3_18325	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CSC3H3_18335	COG0181	hydroxymethylbilane synthase activity
CSC3H3_18355	COG0138	bifunctional purine biosynthesis protein purh
CSC3H3_18365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CSC3H3_18395	COG2183	response to ionizing radiation
CSC3H3_18405	COG0352	thiamine-phosphate diphosphorylase activity
CSC3H3_18415	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CSC3H3_18430	COG1012	belongs to the aldehyde dehydrogenase family
CSC3H3_18435	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CSC3H3_18450	COG0583	DNA-binding transcription factor activity
CSC3H3_18455	COG0840	transmembrane signaling receptor activity
CSC3H3_18460	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CSC3H3_18465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC3H3_18470	COG4558	Periplasmic binding protein
CSC3H3_18475	COG2807	transmembrane transport
CSC3H3_18495	COG0583	DNA-binding transcription factor activity
CSC3H3_18515	COG2067	long-chain fatty acid transport protein
CSC3H3_18520	COG0318	PFAM AMP-dependent synthetase and ligase
CSC3H3_18525	COG0789	Transcriptional regulator
CSC3H3_18530	COG0183	Belongs to the thiolase family
CSC3H3_18535	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSC3H3_18535	COG1024	Enoyl-CoA hydratase
CSC3H3_18540	COG1960	acyl-CoA dehydrogenase activity
CSC3H3_18550	COG1024	Enoyl-CoA hydratase
CSC3H3_18555	COG0300	oxidoreductase activity
CSC3H3_18565	COG2943	transferase activity, transferring hexosyl groups
CSC3H3_18580	COG4208	sulfate ABC transporter
CSC3H3_18585	COG1176	ABC-type spermidine putrescine transport system, permease component I
CSC3H3_18595	COG3842	ATPase activity
CSC3H3_18625	COG0730	response to heat
CSC3H3_18630	COG2188	Transcriptional regulator
CSC3H3_18675	COG1595	DNA-templated transcription, initiation
CSC3H3_18685	COG1741	Belongs to the pirin family
CSC3H3_18690	COG2259	Doxx family
CSC3H3_18700	COG4753	response regulator
CSC3H3_18700	COG2207	Transcriptional regulator
CSC3H3_18705	COG4191	Histidine kinase
CSC3H3_18715	COG2200	EAL domain
CSC3H3_18720	COG2201	protein-glutamate methylesterase activity
CSC3H3_18735	COG0745	RESPONSE REGULATOR receiver
CSC3H3_18785	COG3180	Ammonia monooxygenase
CSC3H3_18790	COG1228	amidohydrolase
CSC3H3_18795	COG2986	histidine ammonia-lyase
CSC3H3_18800	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CSC3H3_18805	COG2188	Transcriptional regulator
CSC3H3_18820	COG0297	glycogen (starch) synthase activity
CSC3H3_18845	COG2226	methyltransferase
CSC3H3_18845	COG0596	Alpha beta hydrolase
CSC3H3_18845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CSC3H3_18860	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CSC3H3_18870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSC3H3_18880	COG3206	protein involved in exopolysaccharide biosynthesis
CSC3H3_18880	COG0489	protein tyrosine kinase activity
CSC3H3_18905	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CSC3H3_18915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSC3H3_18920	COG3181	Tripartite tricarboxylate transporter family receptor
CSC3H3_18945	COG2186	Transcriptional regulator
CSC3H3_18950	COG0028	Belongs to the TPP enzyme family
CSC3H3_18955	COG1216	Glycosyl transferase, family 2
CSC3H3_18970	COG1216	Glycosyl transferase, family 2
CSC3H3_18975	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CSC3H3_18985	COG1215	transferase activity, transferring glycosyl groups
CSC3H3_19000	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CSC3H3_19020	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CSC3H3_19035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSC3H3_19045	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CSC3H3_19045	COG0662	Cupin 2, conserved barrel domain protein
CSC3H3_19065	COG1131	(ABC) transporter
CSC3H3_19075	COG0133	tryptophan synthase activity
CSC3H3_19085	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CSC3H3_19090	COG0285	dihydrofolate synthase activity
CSC3H3_19100	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CSC3H3_19100	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CSC3H3_19115	COG0667	Aldo Keto reductase
CSC3H3_19120	COG0583	DNA-binding transcription factor activity
CSC3H3_19130	COG0492	ferredoxin-NADP+ reductase activity
CSC3H3_19150	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CSC3H3_19160	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CSC3H3_19165	COG0792	nuclease activity
CSC3H3_19180	COG0667	Aldo Keto reductase
CSC3H3_19195	COG2814	Major facilitator Superfamily
CSC3H3_19205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSC3H3_19215	COG2211	Major facilitator Superfamily
CSC3H3_19220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC3H3_19225	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CSC3H3_19230	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CSC3H3_19235	COG1137	ATPase activity
CSC3H3_19275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSC3H3_19280	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CSC3H3_19285	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CSC3H3_19295	COG1420	regulation of RNA biosynthetic process
CSC3H3_19300	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CSC3H3_19315	COG0697	spore germination
CSC3H3_19340	COG0583	DNA-binding transcription factor activity
CSC3H3_19345	COG1216	Glycosyl transferase, family 2
CSC3H3_19350	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CSC3H3_19365	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CSC3H3_19370	COG2992	FlgJ-related protein
CSC3H3_19380	COG0281	malic enzyme
CSC3H3_19380	COG0280	phosphate acetyltransferase
CSC3H3_19405	COG0180	Tryptophanyl-tRNA synthetase
CSC3H3_19420	COG0745	RESPONSE REGULATOR receiver
CSC3H3_19440	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CSC3H3_19470	COG1475	DNA binding
CSC3H3_19475	COG1192	Involved in chromosome partitioning
CSC3H3_19485	COG0445	tRNA wobble uridine modification
CSC3H3_19490	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CSC3H3_19505	COG1331	Highly conserved protein containing a thioredoxin domain
CSC3H3_19510	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CSC3H3_19515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CSC3H3_19530	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CSC3H3_19550	COG1139	Iron-sulfur cluster binding protein
CSC3H3_19555	COG0247	lactate metabolic process
CSC3H3_19565	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CSC3H3_19570	COG0237	dephospho-CoA kinase activity
CSC3H3_19575	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CSC3H3_19580	COG0424	maF-like protein
CSC3H3_19585	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CSC3H3_19595	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CSC3H3_19605	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CSC3H3_19610	COG3030	protein affecting phage T7 exclusion by the F plasmid
CSC3H3_19640	COG0667	Aldo Keto reductase
CSC3H3_19675	COG0189	ligase activity
CSC3H3_19695	COG0606	chelatase, subunit chli
CSC3H3_19715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CSC3H3_19750	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CSC3H3_19760	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CSC3H3_19780	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CSC3H3_19785	COG0656	L-ascorbic acid biosynthetic process
CSC3H3_19795	COG5002	protein histidine kinase activity
CSC3H3_19810	COG0726	polysaccharide deacetylase
CSC3H3_19810	COG1649	PFAM Uncharacterised BCR, COG1649
CSC3H3_19815	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CSC3H3_19820	COG0756	dUTP diphosphatase activity
CSC3H3_19825	COG1959	2 iron, 2 sulfur cluster binding
CSC3H3_19830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CSC3H3_19850	COG1280	lysine exporter protein (LysE YggA)
CSC3H3_19865	COG0251	oxidation-reduction process
CSC3H3_19880	COG1214	PFAM Peptidase M22, glycoprotease
CSC3H3_19915	COG1702	phosphate starvation-inducible protein PhoH
CSC3H3_19925	COG1253	flavin adenine dinucleotide binding
CSC3H3_19930	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CSC3H3_19935	COG1396	sequence-specific DNA binding
CSC3H3_19940	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CSC3H3_19945	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CSC3H3_19950	COG1595	DNA-templated transcription, initiation
CSC3H3_19960	COG4206	TonB-dependent receptor
CSC3H3_19960	COG1629	transport
CSC3H3_19970	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CSC3H3_20000	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CSC3H3_20015	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CSC3H3_20025	COG1185	polyribonucleotide nucleotidyltransferase activity
CSC3H3_20040	COG1592	Rubrerythrin
CSC3H3_20050	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CSC3H3_20075	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CSC3H3_20080	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CSC3H3_20085	COG1268	BioY protein
CSC3H3_20110	COG2308	Evidence 4 Homologs of previously reported genes of
CSC3H3_20115	COG2875	Belongs to the precorrin methyltransferase family
CSC3H3_20140	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CSC3H3_20145	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CSC3H3_20175	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CSC3H3_20220	COG1492	cobalamin metabolic process
CSC3H3_20230	COG2813	Specifically methylates the guanine in position
CSC3H3_20250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSC3H3_20265	COG0583	DNA-binding transcription factor activity
CSC3H3_20275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSC3H3_20280	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CSC3H3_20290	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CSC3H3_20295	COG0840	transmembrane signaling receptor activity
CSC3H3_20300	COG2099	Precorrin-6x reductase
CSC3H3_20325	COG1999	signal sequence binding
CSC3H3_20330	COG1797	cobyrinic acid a,c-diamide synthase activity
CSC3H3_20335	COG2983	Belongs to the UPF0260 family
CSC3H3_20350	COG0071	Belongs to the small heat shock protein (HSP20) family
CSC3H3_20360	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CSC3H3_20360	COG0519	Catalyzes the synthesis of GMP from XMP
CSC3H3_20380	COG0672	)-iron permease
CSC3H3_20385	COG4633	Protein conserved in bacteria
CSC3H3_20445	COG0539	negative regulation of cytoplasmic translation
CSC3H3_20450	COG0616	signal peptide processing
CSC3H3_20455	COG0776	regulation of translation
CSC3H3_20480	COG2814	Major facilitator Superfamily
CSC3H3_20485	COG0730	response to heat
CSC3H3_20495	COG1024	Enoyl-CoA hydratase
CSC3H3_20500	COG0268	Binds directly to 16S ribosomal RNA
CSC3H3_20510	COG4962	Type ii secretion system protein e
CSC3H3_20580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CSC3H3_20610	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CSC3H3_20615	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CSC3H3_20620	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CSC3H3_20625	COG2205	protein histidine kinase activity
CSC3H3_20685	COG1070	Carbohydrate kinase
CSC3H3_20720	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_20720	COG3347	Dehydrogenase
CSC3H3_20725	COG1802	Transcriptional regulator
CSC3H3_20730	COG1063	alcohol dehydrogenase
CSC3H3_20735	COG0246	Mannitol dehydrogenase
CSC3H3_20740	COG2721	sulfolactate sulfo-lyase activity
CSC3H3_20745	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CSC3H3_20750	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CSC3H3_20755	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CSC3H3_20775	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_20780	COG2186	Transcriptional regulator
CSC3H3_20785	COG0473	3-isopropylmalate dehydrogenase activity
CSC3H3_20785	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CSC3H3_20795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CSC3H3_20810	COG3181	Tripartite tricarboxylate transporter family receptor
CSC3H3_20830	COG1175	transmembrane transport
CSC3H3_20840	COG3842	ATPase activity
CSC3H3_20850	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CSC3H3_20855	COG0456	acetyltransferase
CSC3H3_20870	COG1522	sequence-specific DNA binding
CSC3H3_20895	COG2197	response regulator
CSC3H3_20900	COG2197	response regulator
CSC3H3_20905	COG2197	response regulator
CSC3H3_20920	COG0587	DNA-directed DNA polymerase activity
CSC3H3_20940	COG0747	negative chemotaxis
CSC3H3_20950	COG0405	Gamma-glutamyltransferase
CSC3H3_20955	COG0601	transmembrane transport
CSC3H3_20960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC3H3_20965	COG0444	Belongs to the ABC transporter superfamily
CSC3H3_20970	COG4608	Belongs to the ABC transporter superfamily
CSC3H3_20990	COG0601	transmembrane transport
CSC3H3_20995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC3H3_21000	COG0444	Belongs to the ABC transporter superfamily
CSC3H3_21015	COG1921	L-seryl-tRNASec selenium transferase activity
CSC3H3_21040	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CSC3H3_21055	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CSC3H3_21060	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CSC3H3_21130	COG2030	dehydratase
CSC3H3_21135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSC3H3_21145	COG0165	Argininosuccinate lyase
CSC3H3_21165	COG1940	carbohydrate kinase activity
CSC3H3_21180	COG4948	Mandelate Racemase Muconate Lactonizing
CSC3H3_21190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CSC3H3_21195	COG3246	L-lysine catabolic process to acetate
CSC3H3_21210	COG0589	response to stress
CSC3H3_21255	COG1215	transferase activity, transferring glycosyl groups
CSC3H3_21260	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CSC3H3_21290	COG1846	Transcriptional regulator
CSC3H3_21295	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSC3H3_21295	COG1024	Enoyl-CoA hydratase
CSC3H3_21300	COG1960	acyl-CoA dehydrogenase activity
CSC3H3_21315	COG3483	tryptophan 2,3-dioxygenase activity
CSC3H3_21330	COG0300	oxidoreductase activity
CSC3H3_21335	COG0583	DNA-binding transcription factor activity
CSC3H3_21340	COG0583	DNA-binding transcription factor activity
CSC3H3_21350	COG4172	Belongs to the ABC transporter superfamily
CSC3H3_21355	COG0747	negative chemotaxis
CSC3H3_21360	COG0601	transmembrane transport
CSC3H3_21365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC3H3_21375	COG2362	D-Aminopeptidase
CSC3H3_21390	COG0395	ABC-type sugar transport system, permease component
CSC3H3_21405	COG1609	Transcriptional regulator
CSC3H3_21410	COG2030	dehydratase
CSC3H3_21420	COG3254	rhamnose metabolic process
CSC3H3_21435	COG3618	amidohydrolase
CSC3H3_21455	COG0596	Alpha beta hydrolase
CSC3H3_21465	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CSC3H3_21530	COG2204	response regulator
CSC3H3_21580	COG3501	Rhs element vgr protein
CSC3H3_21620	COG0457	Tetratricopeptide repeat
CSC3H3_21630	COG2207	Transcriptional regulator
CSC3H3_21650	COG0673	inositol 2-dehydrogenase activity
CSC3H3_21660	COG3718	enzyme involved in inositol metabolism
CSC3H3_21670	COG3962	Belongs to the TPP enzyme family
CSC3H3_21675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSC3H3_21730	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CSC3H3_21735	COG0625	glutathione transferase activity
CSC3H3_21750	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CSC3H3_21760	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CSC3H3_21785	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CSC3H3_21790	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CSC3H3_21790	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CSC3H3_21795	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CSC3H3_21805	COG1802	Transcriptional regulator
CSC3H3_21815	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CSC3H3_21825	COG0039	L-malate dehydrogenase activity
CSC3H3_21845	COG4172	Belongs to the ABC transporter superfamily
CSC3H3_21850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC3H3_21855	COG0601	transmembrane transport
CSC3H3_21870	COG0473	3-isopropylmalate dehydrogenase activity
CSC3H3_21875	COG2828	Protein conserved in bacteria
CSC3H3_21910	COG1802	Transcriptional regulator
CSC3H3_21920	COG0747	negative chemotaxis
CSC3H3_21930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC3H3_21935	COG0444	Belongs to the ABC transporter superfamily
CSC3H3_21940	COG4608	Belongs to the ABC transporter superfamily
CSC3H3_21945	COG0405	Gamma-glutamyltransferase
CSC3H3_21955	COG4948	Mandelate Racemase Muconate Lactonizing
CSC3H3_21960	COG1414	Transcriptional regulator
CSC3H3_21980	COG1175	transmembrane transport
CSC3H3_21985	COG0395	ABC-type sugar transport system, permease component
CSC3H3_21990	COG3842	ATPase activity
CSC3H3_21995	COG4948	Mandelate Racemase Muconate Lactonizing
CSC3H3_22005	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_22010	COG0179	Fumarylacetoacetate (FAA) hydrolase
CSC3H3_22025	COG1538	Outer membrane efflux protein
CSC3H3_22035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSC3H3_22040	COG0745	RESPONSE REGULATOR receiver
CSC3H3_22045	COG2205	protein histidine kinase activity
CSC3H3_22070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CSC3H3_22080	COG2186	Transcriptional regulator
CSC3H3_22110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSC3H3_22115	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CSC3H3_22130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSC3H3_22150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CSC3H3_22165	COG1120	ATPase activity
CSC3H3_22180	COG3153	acetyltransferase
CSC3H3_22230	COG2124	cytochrome p450
CSC3H3_22250	COG1115	amino acid carrier protein
CSC3H3_22265	COG0493	'glutamate synthase
CSC3H3_22285	COG1309	transcriptional regulator
CSC3H3_22305	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CSC3H3_22310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSC3H3_22315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSC3H3_22340	COG0698	ribose 5-phosphate isomerase
CSC3H3_22345	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CSC3H3_22355	COG1879	ABC-type sugar transport system periplasmic component
CSC3H3_22360	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC3H3_22365	COG1129	ABC transporter
CSC3H3_22395	COG1349	DNA-binding transcription factor activity
CSC3H3_22440	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CSC3H3_22450	COG0673	inositol 2-dehydrogenase activity
CSC3H3_22455	COG0438	transferase activity, transferring glycosyl groups
CSC3H3_22460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSC3H3_22465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CSC3H3_22475	COG2186	Transcriptional regulator
CSC3H3_22480	COG3938	Belongs to the proline racemase family
CSC3H3_22510	COG0235	Class ii aldolase
CSC3H3_22520	COG1082	Xylose isomerase domain protein TIM barrel
CSC3H3_22525	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC3H3_22530	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC3H3_22535	COG1129	ABC transporter
CSC3H3_22555	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CSC3H3_22560	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CSC3H3_22565	COG0583	DNA-binding transcription factor activity
CSC3H3_22575	COG0626	cystathionine gamma-synthase activity
CSC3H3_22580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSC3H3_22585	COG4597	amino acid ABC transporter
CSC3H3_22590	COG0765	amino acid transport
CSC3H3_22595	COG1126	abc transporter atp-binding protein
CSC3H3_22605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CSC3H3_22605	COG2169	Transcriptional regulator
CSC3H3_22615	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CSC3H3_22620	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CSC3H3_22655	COG0746	molybdenum cofactor guanylyltransferase activity
CSC3H3_22660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSC3H3_22675	COG0129	dihydroxy-acid dehydratase activity
CSC3H3_22680	COG0604	alcohol dehydrogenase
CSC3H3_22685	COG0583	DNA-binding transcription factor activity
CSC3H3_22705	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CSC3H3_22715	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CSC3H3_22725	COG2207	Transcriptional regulator
CSC3H3_22730	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_22740	COG0114	fumarate hydratase activity
CSC3H3_22755	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CSC3H3_22760	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CSC3H3_22770	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CSC3H3_22775	COG1301	dicarboxylic acid transport
CSC3H3_22780	COG0251	oxidation-reduction process
CSC3H3_22795	COG0252	asparaginase activity
CSC3H3_22800	COG1126	abc transporter atp-binding protein
CSC3H3_22810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSC3H3_22825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSC3H3_22830	COG1012	belongs to the aldehyde dehydrogenase family
CSC3H3_22850	COG1522	sequence-specific DNA binding
CSC3H3_22890	COG0028	Belongs to the TPP enzyme family
CSC3H3_22900	COG1653	transport
CSC3H3_22945	COG0446	pyridine nucleotide-disulphide oxidoreductase
CSC3H3_22945	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CSC3H3_22950	COG4311	Sarcosine oxidase, delta subunit
CSC3H3_22955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CSC3H3_22960	COG1027	Aspartate ammonia-lyase
CSC3H3_22980	COG0765	amino acid transport
CSC3H3_23105	COG0583	DNA-binding transcription factor activity
CSC3H3_23120	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CSC3H3_23185	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CSC3H3_23195	COG2207	Transcriptional regulator
CSC3H3_23205	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_23220	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC3H3_23230	COG4948	Mandelate Racemase Muconate Lactonizing
CSC3H3_23240	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CSC3H3_23255	COG0583	DNA-binding transcription factor activity
CSC3H3_23290	COG3842	ATPase activity
CSC3H3_23295	COG3842	ATPase activity
CSC3H3_23305	COG0395	ABC-type sugar transport system, permease component
CSC3H3_23320	COG0840	transmembrane signaling receptor activity
CSC3H3_23345	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CSC3H3_23365	COG2188	Transcriptional regulator
CSC3H3_23390	COG2986	histidine ammonia-lyase
CSC3H3_23405	COG4977	sequence-specific DNA binding
CSC3H3_23440	COG0163	prenyltransferase activity
CSC3H3_23445	COG2207	Transcriptional regulator
CSC3H3_23455	COG2733	membrane
CSC3H3_23460	COG0246	Mannitol dehydrogenase
CSC3H3_23465	COG1312	Catalyzes the dehydration of D-mannonate
CSC3H3_23470	COG1802	Transcriptional regulator
CSC3H3_23475	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CSC3H3_23485	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CSC3H3_23490	COG1063	alcohol dehydrogenase
CSC3H3_23505	COG1454	alcohol dehydrogenase
CSC3H3_23510	COG4302	ethanolamine ammonia-lyase activity
CSC3H3_23540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CSC3H3_23550	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_23565	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC3H3_23570	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC3H3_23575	COG1129	ABC transporter
CSC3H3_23585	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CSC3H3_23590	COG1349	DNA-binding transcription factor activity
CSC3H3_23600	COG0179	Fumarylacetoacetate (FAA) hydrolase
CSC3H3_23605	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CSC3H3_23630	COG4638	Rieske (2fe-2S)
CSC3H3_23635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSC3H3_23640	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSC3H3_23650	COG2086	electron transfer activity
CSC3H3_23660	COG0788	formyltetrahydrofolate deformylase activity
CSC3H3_23670	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CSC3H3_23680	COG0446	pyridine nucleotide-disulphide oxidoreductase
CSC3H3_23680	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CSC3H3_23730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CSC3H3_23755	COG0747	negative chemotaxis
CSC3H3_23775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CSC3H3_23780	COG1126	abc transporter atp-binding protein
CSC3H3_23785	COG0765	amino acid transport
CSC3H3_23790	COG4597	amino acid ABC transporter
CSC3H3_23795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSC3H3_23800	COG0583	DNA-binding transcription factor activity
CSC3H3_23820	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CSC3H3_23825	COG2814	Major facilitator Superfamily
CSC3H3_23830	COG4264	IucA IucC family
CSC3H3_23840	COG4264	IucA IucC family
CSC3H3_23845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSC3H3_23850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC3H3_23855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC3H3_23860	COG1120	ATPase activity
CSC3H3_23885	COG0444	Belongs to the ABC transporter superfamily
CSC3H3_23890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC3H3_23895	COG0601	transmembrane transport
CSC3H3_23900	COG0747	negative chemotaxis
CSC3H3_23905	COG1802	Transcriptional regulator
CSC3H3_23915	COG0559	Belongs to the binding-protein-dependent transport system permease family
CSC3H3_23935	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_23940	COG3246	L-lysine catabolic process to acetate
CSC3H3_23945	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSC3H3_23960	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CSC3H3_23975	COG0471	metal ion transport
CSC3H3_23975	COG3273	potassium ion transport
CSC3H3_23980	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CSC3H3_23985	COG4208	sulfate ABC transporter
CSC3H3_23995	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CSC3H3_24000	COG1959	2 iron, 2 sulfur cluster binding
CSC3H3_24005	COG3842	ATPase activity
CSC3H3_24015	COG0395	ABC-type sugar transport system, permease component
CSC3H3_24035	COG2207	Transcriptional regulator
CSC3H3_24050	COG1566	PFAM secretion protein HlyD family protein
CSC3H3_24065	COG1129	ABC transporter
CSC3H3_24070	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC3H3_24075	COG1879	ABC-type sugar transport system periplasmic component
CSC3H3_24080	COG1028	Short-chain dehydrogenase reductase Sdr
CSC3H3_24085	COG2376	Dihydroxyacetone kinase
CSC3H3_24095	COG2376	Dihydroxyacetone kinase
CSC3H3_24115	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CSC3H3_24120	COG2226	methyltransferase
CSC3H3_24120	COG1073	alpha beta