Tharo_1847 64dcef7a7afab471332b0a5bc1dc2e3e 1007 Pfam PF13700 Domain of unknown function (DUF4158) 5 164 1.1E-32 T 14-10-2018 IPR025296 Domain of unknown function DUF4158 Tharo_1847 64dcef7a7afab471332b0a5bc1dc2e3e 1007 Pfam PF01526 Tn3 transposase DDE domain 586 973 1.5E-140 T 14-10-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 Tharo_1974 b7221b9187b5a5ad38cce550eb622ec4 253 Gene3D G3DSA:3.40.50.2300 1 127 6.1E-40 T 14-10-2018 Tharo_1974 b7221b9187b5a5ad38cce550eb622ec4 253 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 234 6.2E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_1974 b7221b9187b5a5ad38cce550eb622ec4 253 SMART SM00862 158 234 3.4E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_1974 b7221b9187b5a5ad38cce550eb622ec4 253 SMART SM00448 7 118 4.8E-43 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1974 b7221b9187b5a5ad38cce550eb622ec4 253 SUPERFAMILY SSF52172 5 128 8.97E-42 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1974 b7221b9187b5a5ad38cce550eb622ec4 253 SUPERFAMILY SSF46894 135 236 3.12E-28 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_1974 b7221b9187b5a5ad38cce550eb622ec4 253 Pfam PF00072 Response regulator receiver domain 9 119 1.6E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1974 b7221b9187b5a5ad38cce550eb622ec4 253 Gene3D G3DSA:1.10.10.10 132 241 3.0E-38 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0189 9fdbfbc56ae50d2fbc1de32eb7d4e3db 306 Gene3D G3DSA:1.10.10.10 3 93 1.6E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0189 9fdbfbc56ae50d2fbc1de32eb7d4e3db 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 72 5.9E-14 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0189 9fdbfbc56ae50d2fbc1de32eb7d4e3db 306 Pfam PF03466 LysR substrate binding domain 99 301 6.5E-14 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_0189 9fdbfbc56ae50d2fbc1de32eb7d4e3db 306 Gene3D G3DSA:3.40.190.10 175 275 2.1E-59 T 14-10-2018 Tharo_0189 9fdbfbc56ae50d2fbc1de32eb7d4e3db 306 SUPERFAMILY SSF53850 95 303 1.56E-41 T 14-10-2018 Tharo_0189 9fdbfbc56ae50d2fbc1de32eb7d4e3db 306 SUPERFAMILY SSF46785 8 89 1.84E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0189 9fdbfbc56ae50d2fbc1de32eb7d4e3db 306 Gene3D G3DSA:3.40.190.10 95 298 2.1E-59 T 14-10-2018 Tharo_0783 11924651fc223e7d5ab11a245f9e36ed 304 SUPERFAMILY SSF52402 9 212 3.03E-61 T 14-10-2018 Tharo_0783 11924651fc223e7d5ab11a245f9e36ed 304 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 12 304 1.2E-124 T 14-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 Tharo_0783 11924651fc223e7d5ab11a245f9e36ed 304 PIRSF PIRSF002936 3 304 1.2E-139 T 14-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 Tharo_0783 11924651fc223e7d5ab11a245f9e36ed 304 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 32 258 2.0E-44 T 14-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 Tharo_0783 11924651fc223e7d5ab11a245f9e36ed 304 Gene3D G3DSA:3.40.50.620 10 214 1.7E-52 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_3054 153aefaa581a0c3bf1f32b1c7783dfdb 314 SMART SM01400 6 122 4.2E-59 T 14-10-2018 Tharo_3054 153aefaa581a0c3bf1f32b1c7783dfdb 314 Gene3D G3DSA:3.40.50.2020 149 290 3.1E-108 T 14-10-2018 Tharo_3054 153aefaa581a0c3bf1f32b1c7783dfdb 314 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 6 122 7.3E-41 T 14-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Tharo_3054 153aefaa581a0c3bf1f32b1c7783dfdb 314 SUPERFAMILY SSF53271 71 305 3.92E-51 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Tharo_3054 153aefaa581a0c3bf1f32b1c7783dfdb 314 Pfam PF14572 Phosphoribosyl synthetase-associated domain 208 313 6.3E-20 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Tharo_3054 153aefaa581a0c3bf1f32b1c7783dfdb 314 Gene3D G3DSA:3.40.50.2020 9 302 3.1E-108 T 14-10-2018 Tharo_3054 153aefaa581a0c3bf1f32b1c7783dfdb 314 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 7 314 1.4E-105 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Tharo_3054 153aefaa581a0c3bf1f32b1c7783dfdb 314 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 130 145 - T 14-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 Tharo_0879 e66fb1202dd246c524763c70df01d95a 402 Pfam PF12704 MacB-like periplasmic core domain 21 244 1.3E-33 T 14-10-2018 IPR025857 MacB-like periplasmic core domain Tharo_0879 e66fb1202dd246c524763c70df01d95a 402 Pfam PF02687 FtsX-like permease family 307 395 2.3E-8 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Tharo_2669 4bcca0aefae3967c51be8eb99b4c061e 324 Gene3D G3DSA:3.20.20.70 164 311 8.0E-108 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_2669 4bcca0aefae3967c51be8eb99b4c061e 324 Gene3D G3DSA:3.90.1170.20 52 320 8.0E-108 T 14-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 Tharo_2669 4bcca0aefae3967c51be8eb99b4c061e 324 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 65 153 2.5E-25 T 14-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 Tharo_2669 4bcca0aefae3967c51be8eb99b4c061e 324 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 156 320 1.4E-58 T 14-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 Tharo_2669 4bcca0aefae3967c51be8eb99b4c061e 324 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 57 320 4.8E-92 T 14-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 Tharo_2669 4bcca0aefae3967c51be8eb99b4c061e 324 SUPERFAMILY SSF51690 156 320 2.08E-58 T 14-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 Tharo_2669 4bcca0aefae3967c51be8eb99b4c061e 324 SUPERFAMILY SSF54675 42 154 5.89E-31 T 14-10-2018 Tharo_2669 4bcca0aefae3967c51be8eb99b4c061e 324 PIRSF PIRSF006250 47 323 9.8E-93 T 14-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 Gene3D G3DSA:3.30.70.270 526 688 2.2E-40 T 14-10-2018 Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 520 677 2.0E-28 T 14-10-2018 IPR000160 GGDEF domain Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 SUPERFAMILY SSF158472 337 384 8.24E-9 T 14-10-2018 Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 Gene3D G3DSA:3.40.50.2300 954 1090 1.0E-29 T 14-10-2018 Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 Gene3D G3DSA:1.20.1480.50 293 389 3.0E-13 T 14-10-2018 Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 SUPERFAMILY SSF52172 959 1079 8.25E-31 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 Pfam PF13426 PAS domain 410 510 2.3E-15 T 14-10-2018 IPR000014 PAS domain Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 Pfam PF00990 Diguanylate cyclase, GGDEF domain 523 677 1.9E-36 T 14-10-2018 IPR000160 GGDEF domain Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 SUPERFAMILY SSF55785 406 509 4.36E-26 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 SMART SM00091 398 468 0.0026 T 14-10-2018 IPR000014 PAS domain Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 SMART SM00086 470 512 1.3E-11 T 14-10-2018 IPR001610 PAC motif Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 Gene3D G3DSA:3.30.450.20 390 525 2.0E-34 T 14-10-2018 Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 Pfam PF00563 EAL domain 699 935 2.3E-75 T 14-10-2018 IPR001633 EAL domain Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 SMART SM00304 336 388 7.3E-13 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 SUPERFAMILY SSF141868 698 947 1.44E-91 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 398 519 1.3E-17 T 14-10-2018 IPR000014 PAS domain Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 SUPERFAMILY SSF55073 528 681 6.59E-34 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 SMART SM00267 512 684 1.1E-38 T 14-10-2018 IPR000160 GGDEF domain Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 Gene3D G3DSA:3.20.20.450 694 949 4.3E-105 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 Pfam PF08376 Nitrate and nitrite sensing 49 297 1.6E-5 T 14-10-2018 IPR013587 Nitrate/nitrite sensing protein Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 SMART SM00052 693 940 1.2E-122 T 14-10-2018 IPR001633 EAL domain Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 Pfam PF00672 HAMP domain 336 383 3.5E-14 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 SMART SM00448 960 1072 7.7E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2993 cf2cb475547da9d6e4f8ec20aa1c5be8 1094 Pfam PF00072 Response regulator receiver domain 963 1072 6.3E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_3099 83e42b34ef1782261dcbff0489235135 279 Pfam PF00005 ABC transporter 18 177 5.4E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_3099 83e42b34ef1782261dcbff0489235135 279 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 227 249 9.9E-7 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal Tharo_3099 83e42b34ef1782261dcbff0489235135 279 SUPERFAMILY SSF52540 1 250 2.3E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3099 83e42b34ef1782261dcbff0489235135 279 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_3099 83e42b34ef1782261dcbff0489235135 279 SMART SM00382 26 250 1.8E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_3099 83e42b34ef1782261dcbff0489235135 279 Gene3D G3DSA:3.40.50.300 1 250 9.1E-59 T 14-10-2018 Tharo_1912 104b735654fc30df3e5ff9cb77da7edc 119 Pfam PF03840 Preprotein translocase SecG subunit 9 77 3.3E-22 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Tharo_1912 104b735654fc30df3e5ff9cb77da7edc 119 PRINTS PR01651 Protein-export SecG membrane protein signature 7 27 2.8E-38 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Tharo_1912 104b735654fc30df3e5ff9cb77da7edc 119 PRINTS PR01651 Protein-export SecG membrane protein signature 27 41 2.8E-38 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Tharo_1912 104b735654fc30df3e5ff9cb77da7edc 119 PRINTS PR01651 Protein-export SecG membrane protein signature 42 58 2.8E-38 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Tharo_1912 104b735654fc30df3e5ff9cb77da7edc 119 PRINTS PR01651 Protein-export SecG membrane protein signature 58 80 2.8E-38 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Tharo_1912 104b735654fc30df3e5ff9cb77da7edc 119 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 8 77 7.0E-27 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Tharo_1653 de813f277a8d2f94f62a8138c843fff1 618 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 7 279 6.7E-119 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Tharo_1653 de813f277a8d2f94f62a8138c843fff1 618 SUPERFAMILY SSF52518 4 378 1.59E-78 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_1653 de813f277a8d2f94f62a8138c843fff1 618 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 9 613 2.2E-260 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Tharo_1653 de813f277a8d2f94f62a8138c843fff1 618 Gene3D G3DSA:3.40.50.920 492 615 8.4E-40 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Tharo_1653 de813f277a8d2f94f62a8138c843fff1 618 Gene3D G3DSA:3.40.50.970 313 487 5.3E-71 T 14-10-2018 Tharo_1653 de813f277a8d2f94f62a8138c843fff1 618 SUPERFAMILY SSF52518 314 501 8.07E-63 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_1653 de813f277a8d2f94f62a8138c843fff1 618 SMART SM00861 316 480 3.9E-76 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Tharo_1653 de813f277a8d2f94f62a8138c843fff1 618 Pfam PF02780 Transketolase, C-terminal domain 492 608 4.6E-26 T 14-10-2018 IPR033248 Transketolase, C-terminal domain Tharo_1653 de813f277a8d2f94f62a8138c843fff1 618 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 6 617 45.711 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Tharo_1653 de813f277a8d2f94f62a8138c843fff1 618 Pfam PF02779 Transketolase, pyrimidine binding domain 315 475 5.4E-45 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Tharo_1653 de813f277a8d2f94f62a8138c843fff1 618 SUPERFAMILY SSF52922 489 614 7.98E-31 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Tharo_1653 de813f277a8d2f94f62a8138c843fff1 618 ProSitePatterns PS00801 Transketolase signature 1. 32 51 - T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Tharo_0147 3ee22e1ce11634ad24bf5cddc1d6d4f3 215 Gene3D G3DSA:2.160.20.80 22 213 6.0E-50 T 14-10-2018 Tharo_0147 3ee22e1ce11634ad24bf5cddc1d6d4f3 215 Pfam PF00805 Pentapeptide repeats (8 copies) 66 105 2.6E-10 T 14-10-2018 IPR001646 Pentapeptide repeat Tharo_0147 3ee22e1ce11634ad24bf5cddc1d6d4f3 215 Pfam PF13599 Pentapeptide repeats (9 copies) 117 192 7.0E-14 T 14-10-2018 IPR001646 Pentapeptide repeat Tharo_0147 3ee22e1ce11634ad24bf5cddc1d6d4f3 215 SUPERFAMILY SSF141571 40 165 4.06E-35 T 14-10-2018 Tharo_1590 cc85ef3776516bca30c24a83a75b057e 402 Pfam PF00155 Aminotransferase class I and II 31 396 1.6E-79 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Tharo_1590 cc85ef3776516bca30c24a83a75b057e 402 PRINTS PR00799 Aspartate aminotransferase signature 345 363 6.0E-39 T 14-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 Tharo_1590 cc85ef3776516bca30c24a83a75b057e 402 PRINTS PR00799 Aspartate aminotransferase signature 277 302 6.0E-39 T 14-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 Tharo_1590 cc85ef3776516bca30c24a83a75b057e 402 PRINTS PR00799 Aspartate aminotransferase signature 179 198 6.0E-39 T 14-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 Tharo_1590 cc85ef3776516bca30c24a83a75b057e 402 PRINTS PR00799 Aspartate aminotransferase signature 210 222 6.0E-39 T 14-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 Tharo_1590 cc85ef3776516bca30c24a83a75b057e 402 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 247 260 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Tharo_1590 cc85ef3776516bca30c24a83a75b057e 402 SUPERFAMILY SSF53383 3 401 3.17E-118 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_1590 cc85ef3776516bca30c24a83a75b057e 402 Gene3D G3DSA:3.90.1150.10 9 396 1.4E-161 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_1590 cc85ef3776516bca30c24a83a75b057e 402 Gene3D G3DSA:3.40.640.10 64 304 1.4E-161 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 Gene3D G3DSA:3.30.70.1320 143 348 9.2E-228 T 14-10-2018 Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 Gene3D G3DSA:1.20.1640.10 530 1078 9.2E-228 T 14-10-2018 Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 Gene3D G3DSA:3.30.70.1430 589 699 9.2E-228 T 14-10-2018 Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 SUPERFAMILY SSF82693 585 700 1.73E-11 T 14-10-2018 Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 SUPERFAMILY SSF82693 160 346 2.22E-8 T 14-10-2018 Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 PRINTS PR00702 Acriflavin resistance protein family signature 17 41 6.4E-29 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 PRINTS PR00702 Acriflavin resistance protein family signature 488 511 6.4E-29 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 PRINTS PR00702 Acriflavin resistance protein family signature 380 401 6.4E-29 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 6.4E-29 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 PRINTS PR00702 Acriflavin resistance protein family signature 408 432 6.4E-29 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 PRINTS PR00702 Acriflavin resistance protein family signature 45 63 6.4E-29 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 SUPERFAMILY SSF82866 900 1082 9.02E-38 T 14-10-2018 Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 Gene3D G3DSA:1.20.1640.10 21 529 9.2E-228 T 14-10-2018 Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 Pfam PF00873 AcrB/AcrD/AcrF family 14 859 3.0E-117 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 Pfam PF00873 AcrB/AcrD/AcrF family 905 1079 4.0E-29 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 SUPERFAMILY SSF82714 747 836 1.83E-8 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 Gene3D G3DSA:3.30.70.1430 47 850 9.2E-228 T 14-10-2018 Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 Gene3D G3DSA:3.30.2090.10 189 280 9.2E-228 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 SUPERFAMILY SSF82714 194 275 3.4E-15 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 Gene3D G3DSA:3.30.70.1440 700 923 9.2E-228 T 14-10-2018 Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 SUPERFAMILY SSF82866 313 514 4.97E-37 T 14-10-2018 Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 SUPERFAMILY SSF82693 47 130 1.52E-17 T 14-10-2018 Tharo_2689 75b33e9a589d16cd9bcbab01367930fb 1096 Gene3D G3DSA:3.30.2090.10 748 842 9.2E-228 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_2733 c4661f508914ea5bf2163fe3134855ab 167 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 160 27.054 T 14-10-2018 IPR022973 Ribosomal protein L10 Tharo_2733 c4661f508914ea5bf2163fe3134855ab 167 Gene3D G3DSA:3.30.70.1730 5 133 3.4E-33 T 14-10-2018 Tharo_2733 c4661f508914ea5bf2163fe3134855ab 167 SUPERFAMILY SSF160369 4 159 1.57E-49 T 14-10-2018 Tharo_2733 c4661f508914ea5bf2163fe3134855ab 167 Pfam PF00466 Ribosomal protein L10 6 100 6.3E-23 T 14-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 Tharo_1612 5aae05a6b6b23b8e1bdbb58e3f381787 478 SUPERFAMILY SSF50156 385 475 5.72E-5 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 Tharo_1612 5aae05a6b6b23b8e1bdbb58e3f381787 478 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 32 473 2.8E-139 T 14-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 Tharo_1612 5aae05a6b6b23b8e1bdbb58e3f381787 478 Gene3D G3DSA:2.30.42.10 266 373 9.2E-26 T 14-10-2018 Tharo_1612 5aae05a6b6b23b8e1bdbb58e3f381787 478 Gene3D G3DSA:2.30.42.10 391 478 2.4E-6 T 14-10-2018 Tharo_1612 5aae05a6b6b23b8e1bdbb58e3f381787 478 SUPERFAMILY SSF50156 242 366 1.35E-20 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 Tharo_1612 5aae05a6b6b23b8e1bdbb58e3f381787 478 SUPERFAMILY SSF50494 10 281 1.41E-64 T 14-10-2018 IPR009003 Peptidase S1, PA clan Tharo_1612 5aae05a6b6b23b8e1bdbb58e3f381787 478 PRINTS PR00834 HtrA/DegQ protease family signature 169 193 1.0E-50 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Tharo_1612 5aae05a6b6b23b8e1bdbb58e3f381787 478 PRINTS PR00834 HtrA/DegQ protease family signature 129 149 1.0E-50 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Tharo_1612 5aae05a6b6b23b8e1bdbb58e3f381787 478 PRINTS PR00834 HtrA/DegQ protease family signature 203 220 1.0E-50 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Tharo_1612 5aae05a6b6b23b8e1bdbb58e3f381787 478 PRINTS PR00834 HtrA/DegQ protease family signature 225 242 1.0E-50 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Tharo_1612 5aae05a6b6b23b8e1bdbb58e3f381787 478 PRINTS PR00834 HtrA/DegQ protease family signature 311 323 1.0E-50 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Tharo_1612 5aae05a6b6b23b8e1bdbb58e3f381787 478 PRINTS PR00834 HtrA/DegQ protease family signature 108 120 1.0E-50 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Tharo_1612 5aae05a6b6b23b8e1bdbb58e3f381787 478 Pfam PF13365 Trypsin-like peptidase domain 99 232 8.1E-35 T 14-10-2018 Tharo_1612 5aae05a6b6b23b8e1bdbb58e3f381787 478 Pfam PF13180 PDZ domain 271 360 1.5E-16 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Tharo_1612 5aae05a6b6b23b8e1bdbb58e3f381787 478 SMART SM00228 385 467 0.55 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Tharo_1612 5aae05a6b6b23b8e1bdbb58e3f381787 478 SMART SM00228 271 353 1.3E-11 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Tharo_1612 5aae05a6b6b23b8e1bdbb58e3f381787 478 Gene3D G3DSA:2.40.10.120 30 264 1.4E-80 T 14-10-2018 Tharo_0527 a3fe5c5f0eb6f6ef9a19fe0bfe462f87 393 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 25 305 1.0E-63 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Tharo_0527 a3fe5c5f0eb6f6ef9a19fe0bfe462f87 393 Pfam PF01545 Cation efflux family 29 222 2.9E-36 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Tharo_0527 a3fe5c5f0eb6f6ef9a19fe0bfe462f87 393 SUPERFAMILY SSF161111 22 223 7.32E-44 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Tharo_0527 a3fe5c5f0eb6f6ef9a19fe0bfe462f87 393 Gene3D G3DSA:1.20.1510.10 23 221 8.2E-52 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Tharo_0527 a3fe5c5f0eb6f6ef9a19fe0bfe462f87 393 Pfam PF16916 Dimerisation domain of Zinc Transporter 226 304 7.6E-24 T 14-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain Tharo_0527 a3fe5c5f0eb6f6ef9a19fe0bfe462f87 393 SUPERFAMILY SSF160240 226 305 9.42E-21 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 Tharo_0527 a3fe5c5f0eb6f6ef9a19fe0bfe462f87 393 Gene3D G3DSA:3.30.70.1350 222 311 1.2E-21 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 Tharo_0716 45ca3fb7142b553f89340a10e4f03efd 759 Gene3D G3DSA:3.40.50.300 495 749 2.0E-24 T 14-10-2018 Tharo_0716 45ca3fb7142b553f89340a10e4f03efd 759 Gene3D G3DSA:3.40.50.10810 312 454 1.9E-6 T 14-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily Tharo_0716 45ca3fb7142b553f89340a10e4f03efd 759 SUPERFAMILY SSF52540 351 736 3.06E-29 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0716 45ca3fb7142b553f89340a10e4f03efd 759 SMART SM00487 69 413 1.9E-9 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Tharo_0716 45ca3fb7142b553f89340a10e4f03efd 759 Gene3D G3DSA:3.40.50.300 63 179 3.0E-8 T 14-10-2018 Tharo_0716 45ca3fb7142b553f89340a10e4f03efd 759 SUPERFAMILY SSF52540 69 411 7.28E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0716 45ca3fb7142b553f89340a10e4f03efd 759 Pfam PF00271 Helicase conserved C-terminal domain 585 695 1.6E-5 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_2224 8bc0ae454002040ba53090370155aac9 643 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 29 38 - T 14-10-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0051082 Tharo_2224 8bc0ae454002040ba53090370155aac9 643 Gene3D G3DSA:3.30.230.80 241 412 8.2E-67 T 14-10-2018 Tharo_2224 8bc0ae454002040ba53090370155aac9 643 PRINTS PR00775 90kDa heat shock protein signature 79 96 9.9E-60 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal Tharo_2224 8bc0ae454002040ba53090370155aac9 643 PRINTS PR00775 90kDa heat shock protein signature 124 146 9.9E-60 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal Tharo_2224 8bc0ae454002040ba53090370155aac9 643 PRINTS PR00775 90kDa heat shock protein signature 30 52 9.9E-60 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal Tharo_2224 8bc0ae454002040ba53090370155aac9 643 PRINTS PR00775 90kDa heat shock protein signature 97 114 9.9E-60 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal Tharo_2224 8bc0ae454002040ba53090370155aac9 643 PRINTS PR00775 90kDa heat shock protein signature 180 197 9.9E-60 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal Tharo_2224 8bc0ae454002040ba53090370155aac9 643 PRINTS PR00775 90kDa heat shock protein signature 198 216 9.9E-60 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal Tharo_2224 8bc0ae454002040ba53090370155aac9 643 PRINTS PR00775 90kDa heat shock protein signature 9 29 9.9E-60 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal Tharo_2224 8bc0ae454002040ba53090370155aac9 643 SUPERFAMILY SSF55874 8 224 4.06E-65 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2224 8bc0ae454002040ba53090370155aac9 643 Hamap MF_00505 Chaperone protein HtpG [htpG]. 6 638 32.494 T 14-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 Tharo_2224 8bc0ae454002040ba53090370155aac9 643 SMART SM00387 31 192 7.5E-7 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2224 8bc0ae454002040ba53090370155aac9 643 Gene3D G3DSA:1.20.120.790 508 639 1.0E-45 T 14-10-2018 IPR037196 HSP90, C-terminal domain Tharo_2224 8bc0ae454002040ba53090370155aac9 643 Gene3D G3DSA:3.30.565.10 1 236 3.4E-74 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2224 8bc0ae454002040ba53090370155aac9 643 Pfam PF00183 Hsp90 protein 221 638 2.4E-134 T 14-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 Tharo_2224 8bc0ae454002040ba53090370155aac9 643 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 190 1.6E-11 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2224 8bc0ae454002040ba53090370155aac9 643 PIRSF PIRSF002583 1 643 3.4E-211 T 14-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 Tharo_2224 8bc0ae454002040ba53090370155aac9 643 SUPERFAMILY SSF110942 527 638 5.23E-37 T 14-10-2018 IPR037196 HSP90, C-terminal domain Tharo_2224 8bc0ae454002040ba53090370155aac9 643 SUPERFAMILY SSF54211 242 501 1.37E-97 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_2224 8bc0ae454002040ba53090370155aac9 643 Gene3D G3DSA:3.40.50.11260 413 502 2.7E-33 T 14-10-2018 Tharo_1637 34ac9c2c1ca116a099aaa41e88220324 395 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 210 379 5.2E-10 T 14-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 Tharo_1637 34ac9c2c1ca116a099aaa41e88220324 395 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 56 116 1.5E-4 T 14-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 Tharo_1637 34ac9c2c1ca116a099aaa41e88220324 395 Gene3D G3DSA:3.40.720.10 45 394 2.5E-30 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 Tharo_1637 34ac9c2c1ca116a099aaa41e88220324 395 SUPERFAMILY SSF53649 52 393 6.33E-42 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 Tharo_2275 549cc39547d4468e14f74823a7844daf 503 Gene3D G3DSA:1.20.1480.50 155 250 8.8E-11 T 14-10-2018 Tharo_2275 549cc39547d4468e14f74823a7844daf 503 SUPERFAMILY SSF158472 196 245 2.48E-8 T 14-10-2018 Tharo_2275 549cc39547d4468e14f74823a7844daf 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 473 486 2.2E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2275 549cc39547d4468e14f74823a7844daf 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 467 2.2E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2275 549cc39547d4468e14f74823a7844daf 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 430 2.2E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2275 549cc39547d4468e14f74823a7844daf 503 Pfam PF00672 HAMP domain 196 243 3.5E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_2275 549cc39547d4468e14f74823a7844daf 503 SUPERFAMILY SSF47384 247 330 8.44E-17 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_2275 549cc39547d4468e14f74823a7844daf 503 Pfam PF00512 His Kinase A (phospho-acceptor) domain 264 327 5.0E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_2275 549cc39547d4468e14f74823a7844daf 503 SMART SM00387 371 489 2.1E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2275 549cc39547d4468e14f74823a7844daf 503 SUPERFAMILY SSF55874 320 487 1.44E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2275 549cc39547d4468e14f74823a7844daf 503 Gene3D G3DSA:1.10.287.130 251 330 9.5E-15 T 14-10-2018 Tharo_2275 549cc39547d4468e14f74823a7844daf 503 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 371 487 6.7E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2275 549cc39547d4468e14f74823a7844daf 503 SMART SM00388 262 330 4.9E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_2275 549cc39547d4468e14f74823a7844daf 503 SMART SM00304 195 247 1.8E-12 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_2275 549cc39547d4468e14f74823a7844daf 503 Gene3D G3DSA:3.30.565.10 331 488 2.9E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2392 92282ad6223ba6268f68c4ddd99a1cb6 154 Hamap MF_00821 Protein-export protein SecB [secB]. 1 144 32.849 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 Tharo_2392 92282ad6223ba6268f68c4ddd99a1cb6 154 Gene3D G3DSA:3.10.420.10 1 151 1.5E-57 T 14-10-2018 IPR035958 SecB-like superfamily Tharo_2392 92282ad6223ba6268f68c4ddd99a1cb6 154 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 96 118 4.7E-32 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 Tharo_2392 92282ad6223ba6268f68c4ddd99a1cb6 154 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 11 28 4.7E-32 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 Tharo_2392 92282ad6223ba6268f68c4ddd99a1cb6 154 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 122 140 4.7E-32 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 Tharo_2392 92282ad6223ba6268f68c4ddd99a1cb6 154 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 72 92 4.7E-32 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 Tharo_2392 92282ad6223ba6268f68c4ddd99a1cb6 154 SUPERFAMILY SSF54611 3 140 2.83E-51 T 14-10-2018 IPR035958 SecB-like superfamily Tharo_2392 92282ad6223ba6268f68c4ddd99a1cb6 154 Pfam PF02556 Preprotein translocase subunit SecB 3 142 1.7E-56 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 Tharo_2392 92282ad6223ba6268f68c4ddd99a1cb6 154 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 3 142 1.5E-53 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 Tharo_0782 52b84b9093b31d7cf79f571d4506378a 426 SUPERFAMILY SSF50447 227 319 4.48E-18 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Tharo_0782 52b84b9093b31d7cf79f571d4506378a 426 PRINTS PR00315 GTP-binding elongation factor signature 95 105 6.4E-12 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_0782 52b84b9093b31d7cf79f571d4506378a 426 PRINTS PR00315 GTP-binding elongation factor signature 75 83 6.4E-12 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_0782 52b84b9093b31d7cf79f571d4506378a 426 PRINTS PR00315 GTP-binding elongation factor signature 16 29 6.4E-12 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_0782 52b84b9093b31d7cf79f571d4506378a 426 PRINTS PR00315 GTP-binding elongation factor signature 148 157 6.4E-12 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_0782 52b84b9093b31d7cf79f571d4506378a 426 PRINTS PR00315 GTP-binding elongation factor signature 111 122 6.4E-12 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_0782 52b84b9093b31d7cf79f571d4506378a 426 SUPERFAMILY SSF50465 324 425 4.56E-34 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal Tharo_0782 52b84b9093b31d7cf79f571d4506378a 426 Gene3D G3DSA:2.40.30.10 226 320 7.5E-24 T 14-10-2018 Tharo_0782 52b84b9093b31d7cf79f571d4506378a 426 SUPERFAMILY SSF52540 14 214 1.77E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0782 52b84b9093b31d7cf79f571d4506378a 426 Gene3D G3DSA:2.40.30.10 322 425 9.4E-38 T 14-10-2018 Tharo_0782 52b84b9093b31d7cf79f571d4506378a 426 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 15 425 1.4E-176 T 14-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 Tharo_0782 52b84b9093b31d7cf79f571d4506378a 426 Pfam PF00009 Elongation factor Tu GTP binding domain 15 211 1.8E-40 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_0782 52b84b9093b31d7cf79f571d4506378a 426 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 68 83 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site Tharo_0782 52b84b9093b31d7cf79f571d4506378a 426 Gene3D G3DSA:3.40.50.300 8 222 4.3E-66 T 14-10-2018 Tharo_0667 e61f70ad4bf98c771fedcbeefd6231e3 164 Gene3D G3DSA:3.40.50.620 1 146 5.3E-34 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_0667 e61f70ad4bf98c771fedcbeefd6231e3 164 Pfam PF00582 Universal stress protein family 1 146 2.0E-29 T 14-10-2018 IPR006016 UspA Tharo_0667 e61f70ad4bf98c771fedcbeefd6231e3 164 PRINTS PR01438 Universal stress protein signature 106 118 1.2E-17 T 14-10-2018 IPR006015 Universal stress protein A Tharo_0667 e61f70ad4bf98c771fedcbeefd6231e3 164 PRINTS PR01438 Universal stress protein signature 2 20 1.2E-17 T 14-10-2018 IPR006015 Universal stress protein A Tharo_0667 e61f70ad4bf98c771fedcbeefd6231e3 164 PRINTS PR01438 Universal stress protein signature 124 146 1.2E-17 T 14-10-2018 IPR006015 Universal stress protein A Tharo_0667 e61f70ad4bf98c771fedcbeefd6231e3 164 SUPERFAMILY SSF52402 1 146 1.67E-33 T 14-10-2018 Tharo_1012 d6e840010f17ddeb6024c615e0168eaa 934 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 462 479 - T 14-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 Tharo_1012 d6e840010f17ddeb6024c615e0168eaa 934 Pfam PF00384 Molybdopterin oxidoreductase 88 516 4.9E-81 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1012 d6e840010f17ddeb6024c615e0168eaa 934 Gene3D G3DSA:1.10.10.1100 883 933 5.4E-8 T 14-10-2018 Tharo_1012 d6e840010f17ddeb6024c615e0168eaa 934 Gene3D G3DSA:2.40.40.20 610 737 5.4E-38 T 14-10-2018 Tharo_1012 d6e840010f17ddeb6024c615e0168eaa 934 PIRSF PIRSF036643 6 756 2.0E-161 T 14-10-2018 Tharo_1012 d6e840010f17ddeb6024c615e0168eaa 934 Gene3D G3DSA:3.40.50.740 99 572 1.3E-188 T 14-10-2018 Tharo_1012 d6e840010f17ddeb6024c615e0168eaa 934 Pfam PF04324 BFD-like [2Fe-2S] binding domain 883 930 3.1E-8 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain Tharo_1012 d6e840010f17ddeb6024c615e0168eaa 934 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 36 54 - T 14-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 Tharo_1012 d6e840010f17ddeb6024c615e0168eaa 934 SUPERFAMILY SSF50692 591 737 1.54E-41 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Tharo_1012 d6e840010f17ddeb6024c615e0168eaa 934 SUPERFAMILY SSF53706 27 604 5.1E-195 T 14-10-2018 Tharo_1012 d6e840010f17ddeb6024c615e0168eaa 934 Pfam PF01568 Molydopterin dinucleotide binding domain 620 730 6.0E-29 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 Tharo_1012 d6e840010f17ddeb6024c615e0168eaa 934 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 33 80 1.6E-16 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1012 d6e840010f17ddeb6024c615e0168eaa 934 Gene3D G3DSA:2.20.25.90 27 83 1.5E-15 T 14-10-2018 Tharo_1012 d6e840010f17ddeb6024c615e0168eaa 934 Gene3D G3DSA:3.40.228.10 168 369 1.3E-188 T 14-10-2018 Tharo_1012 d6e840010f17ddeb6024c615e0168eaa 934 SMART SM00926 31 85 6.5E-15 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_0013 7bf4cbe47884c5a2c7981e948c95468a 92 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 90 7.4E-15 T 14-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Tharo_0013 7bf4cbe47884c5a2c7981e948c95468a 92 Gene3D G3DSA:3.30.2310.20 1 92 5.8E-13 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_0013 7bf4cbe47884c5a2c7981e948c95468a 92 SUPERFAMILY SSF143011 1 88 1.96E-6 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_0038 d8e2baa5e061826c107703d3b88d7524 540 Pfam PF16658 Class II release factor RF3, C-terminal domain 394 520 3.8E-41 T 14-10-2018 IPR032090 Peptide chain release factor 3, C-terminal Tharo_0038 d8e2baa5e061826c107703d3b88d7524 540 PRINTS PR00315 GTP-binding elongation factor signature 89 99 8.6E-12 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_0038 d8e2baa5e061826c107703d3b88d7524 540 PRINTS PR00315 GTP-binding elongation factor signature 141 150 8.6E-12 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_0038 d8e2baa5e061826c107703d3b88d7524 540 PRINTS PR00315 GTP-binding elongation factor signature 69 77 8.6E-12 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_0038 d8e2baa5e061826c107703d3b88d7524 540 PRINTS PR00315 GTP-binding elongation factor signature 105 116 8.6E-12 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_0038 d8e2baa5e061826c107703d3b88d7524 540 PRINTS PR00315 GTP-binding elongation factor signature 19 32 8.6E-12 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_0038 d8e2baa5e061826c107703d3b88d7524 540 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 8 533 50.885 T 14-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 Tharo_0038 d8e2baa5e061826c107703d3b88d7524 540 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 10 535 3.5E-224 T 14-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 Tharo_0038 d8e2baa5e061826c107703d3b88d7524 540 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 18 151 4.3E-21 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Tharo_0038 d8e2baa5e061826c107703d3b88d7524 540 Gene3D G3DSA:3.40.50.300 114 277 3.9E-104 T 14-10-2018 Tharo_0038 d8e2baa5e061826c107703d3b88d7524 540 Pfam PF00009 Elongation factor Tu GTP binding domain 16 279 1.5E-50 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_0038 d8e2baa5e061826c107703d3b88d7524 540 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 62 77 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site Tharo_0038 d8e2baa5e061826c107703d3b88d7524 540 Pfam PF03144 Elongation factor Tu domain 2 321 387 1.7E-8 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Tharo_0038 d8e2baa5e061826c107703d3b88d7524 540 SUPERFAMILY SSF52540 13 279 1.1E-86 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0038 d8e2baa5e061826c107703d3b88d7524 540 Gene3D G3DSA:3.40.50.300 76 386 3.9E-104 T 14-10-2018 Tharo_0038 d8e2baa5e061826c107703d3b88d7524 540 Gene3D G3DSA:3.30.70.3280 397 535 5.1E-43 T 14-10-2018 IPR038467 Peptide chain release factor 3, C-terminal domain superfamily Tharo_0038 d8e2baa5e061826c107703d3b88d7524 540 SUPERFAMILY SSF50447 263 398 6.8E-29 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Tharo_0038 d8e2baa5e061826c107703d3b88d7524 540 SUPERFAMILY SSF54980 399 472 1.37E-15 T 14-10-2018 IPR035647 EF-G domain III/V-like Tharo_0352 8866985167183f77cfd468853172a65d 249 Pfam PF02108 Flagellar assembly protein FliH 104 229 1.5E-33 T 14-10-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE Tharo_0352 8866985167183f77cfd468853172a65d 249 PRINTS PR01003 Flagellar assembly protein FliH signature 86 104 3.3E-18 T 14-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 Tharo_0352 8866985167183f77cfd468853172a65d 249 PRINTS PR01003 Flagellar assembly protein FliH signature 211 236 3.3E-18 T 14-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 Tharo_0352 8866985167183f77cfd468853172a65d 249 PRINTS PR01003 Flagellar assembly protein FliH signature 63 85 3.3E-18 T 14-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 Tharo_0352 8866985167183f77cfd468853172a65d 249 PRINTS PR01003 Flagellar assembly protein FliH signature 125 142 3.3E-18 T 14-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 Tharo_0352 8866985167183f77cfd468853172a65d 249 PRINTS PR01003 Flagellar assembly protein FliH signature 10 29 3.3E-18 T 14-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 Tharo_0352 8866985167183f77cfd468853172a65d 249 PRINTS PR01003 Flagellar assembly protein FliH signature 194 210 3.3E-18 T 14-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 Tharo_0352 8866985167183f77cfd468853172a65d 249 PRINTS PR01003 Flagellar assembly protein FliH signature 166 193 3.3E-18 T 14-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 Tharo_1325 de438e392f28ac605dc18a205c42622d 1615 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 76 1612 0.0 T 14-10-2018 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 Tharo_1325 de438e392f28ac605dc18a205c42622d 1615 SUPERFAMILY SSF51735 956 1239 2.69E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1325 de438e392f28ac605dc18a205c42622d 1615 PIRSF PIRSF036761 1 1615 0.0 T 14-10-2018 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 Tharo_1325 de438e392f28ac605dc18a205c42622d 1615 SUPERFAMILY SSF53223 766 951 4.8E-25 T 14-10-2018 Tharo_2916 a37f58df7ed49e5b4979247aaf7f6e7f 664 Gene3D G3DSA:3.30.300.30 528 653 1.7E-10 T 14-10-2018 Tharo_2916 a37f58df7ed49e5b4979247aaf7f6e7f 664 Gene3D G3DSA:3.40.50.12780 84 527 1.1E-59 T 14-10-2018 Tharo_2916 a37f58df7ed49e5b4979247aaf7f6e7f 664 SUPERFAMILY SSF56801 24 652 2.35E-127 T 14-10-2018 Tharo_2916 a37f58df7ed49e5b4979247aaf7f6e7f 664 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 7 656 6.7E-243 T 14-10-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 Tharo_2916 a37f58df7ed49e5b4979247aaf7f6e7f 664 ProSitePatterns PS00455 Putative AMP-binding domain signature. 273 284 - T 14-10-2018 IPR020845 AMP-binding, conserved site Tharo_2916 a37f58df7ed49e5b4979247aaf7f6e7f 664 Pfam PF00501 AMP-binding enzyme 112 530 6.3E-47 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Tharo_2916 a37f58df7ed49e5b4979247aaf7f6e7f 664 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 39 94 1.5E-12 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 Tharo_2535 8bc71ae970f98fbb588e5be0733baa26 85 Pfam PF14451 Mut7-C ubiquitin 5 80 6.1E-8 T 14-10-2018 IPR027798 Ubiquitin Mut7-C domain Tharo_2535 8bc71ae970f98fbb588e5be0733baa26 85 SUPERFAMILY SSF54285 6 85 3.34E-10 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp Tharo_2535 8bc71ae970f98fbb588e5be0733baa26 85 Gene3D G3DSA:3.10.20.30 1 85 4.3E-11 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Tharo_2958 8ea952469d8c43a4670c1dc614c0ad91 721 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 313 702 1.7E-148 T 14-10-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Tharo_2958 8ea952469d8c43a4670c1dc614c0ad91 721 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 527 564 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Tharo_2958 8ea952469d8c43a4670c1dc614c0ad91 721 Gene3D G3DSA:3.40.640.10 362 612 1.2E-139 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_2958 8ea952469d8c43a4670c1dc614c0ad91 721 Gene3D G3DSA:3.90.1150.10 316 692 1.2E-139 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_2958 8ea952469d8c43a4670c1dc614c0ad91 721 Pfam PF00491 Arginase family 17 302 8.7E-53 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 Tharo_2958 8ea952469d8c43a4670c1dc614c0ad91 721 Gene3D G3DSA:3.40.800.10 17 307 4.9E-77 T 14-10-2018 Tharo_2958 8ea952469d8c43a4670c1dc614c0ad91 721 ProSitePatterns PS01053 Arginase family signature. 234 255 - T 14-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 Tharo_2958 8ea952469d8c43a4670c1dc614c0ad91 721 PRINTS PR00116 Arginase signature 129 156 3.3E-25 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 Tharo_2958 8ea952469d8c43a4670c1dc614c0ad91 721 PRINTS PR00116 Arginase signature 231 260 3.3E-25 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 Tharo_2958 8ea952469d8c43a4670c1dc614c0ad91 721 PRINTS PR00116 Arginase signature 105 120 3.3E-25 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 Tharo_2958 8ea952469d8c43a4670c1dc614c0ad91 721 PRINTS PR00116 Arginase signature 181 199 3.3E-25 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 Tharo_2958 8ea952469d8c43a4670c1dc614c0ad91 721 SUPERFAMILY SSF53383 307 703 2.39E-120 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_2958 8ea952469d8c43a4670c1dc614c0ad91 721 SUPERFAMILY SSF52768 18 305 4.5E-63 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily Tharo_2958 8ea952469d8c43a4670c1dc614c0ad91 721 Pfam PF00202 Aminotransferase class-III 320 701 6.7E-112 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Tharo_3320 d684f01e159c267d9161a9badcd067c4 201 Hamap MF_01405 dITP/XTP pyrophosphatase. 3 198 46.882 T 14-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 Tharo_3320 d684f01e159c267d9161a9badcd067c4 201 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 5 196 2.5E-48 T 14-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 Tharo_3320 d684f01e159c267d9161a9badcd067c4 201 SUPERFAMILY SSF52972 3 197 3.4E-67 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Tharo_3320 d684f01e159c267d9161a9badcd067c4 201 Gene3D G3DSA:3.90.950.10 1 200 1.6E-69 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Tharo_3320 d684f01e159c267d9161a9badcd067c4 201 Pfam PF01725 Ham1 family 5 194 3.1E-51 T 14-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 Tharo_3259 fad077fc30974077e57aca71c0bb64c0 226 PIRSF PIRSF026326 4 225 2.3E-88 T 14-10-2018 IPR027023 Putative lipopolysaccharide kinase InaA Tharo_3259 fad077fc30974077e57aca71c0bb64c0 226 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 15 216 8.0E-55 T 14-10-2018 Tharo_3259 fad077fc30974077e57aca71c0bb64c0 226 SUPERFAMILY SSF56112 13 183 4.01E-15 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Tharo_1096 34fa1248c20fbbc91ef4d76685ef5ea9 276 SUPERFAMILY SSF53213 13 272 2.88E-82 T 14-10-2018 Tharo_1096 34fa1248c20fbbc91ef4d76685ef5ea9 276 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 17 261 5.7E-39 T 14-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 Tharo_1096 34fa1248c20fbbc91ef4d76685ef5ea9 276 PIRSF PIRSF006157 9 276 5.5E-86 T 14-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 Tharo_1096 34fa1248c20fbbc91ef4d76685ef5ea9 276 Gene3D G3DSA:3.40.830.10 6 275 8.5E-87 T 14-10-2018 Tharo_3183 5658630072e701b739b2ba3949128691 919 TIGRFAM TIGR00593 pola: DNA polymerase I 4 919 6.0E-279 T 14-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_3183 5658630072e701b739b2ba3949128691 919 ProSitePatterns PS00447 DNA polymerase family A signature. 745 764 - T 14-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_3183 5658630072e701b739b2ba3949128691 919 Pfam PF00476 DNA polymerase family A 543 917 9.1E-153 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_3183 5658630072e701b739b2ba3949128691 919 Gene3D G3DSA:1.20.1060.10 534 649 1.8E-41 T 14-10-2018 Tharo_3183 5658630072e701b739b2ba3949128691 919 SUPERFAMILY SSF88723 1 165 8.69E-55 T 14-10-2018 IPR029060 PIN-like domain superfamily Tharo_3183 5658630072e701b739b2ba3949128691 919 SUPERFAMILY SSF47807 166 280 1.47E-30 T 14-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily Tharo_3183 5658630072e701b739b2ba3949128691 919 SUPERFAMILY SSF56672 514 919 7.78E-154 T 14-10-2018 Tharo_3183 5658630072e701b739b2ba3949128691 919 SUPERFAMILY SSF53098 325 508 2.56E-55 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_3183 5658630072e701b739b2ba3949128691 919 Gene3D G3DSA:1.10.150.20 169 241 1.4E-88 T 14-10-2018 Tharo_3183 5658630072e701b739b2ba3949128691 919 PRINTS PR00868 DNA-polymerase family A (pol I) signature 721 734 1.1E-77 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_3183 5658630072e701b739b2ba3949128691 919 PRINTS PR00868 DNA-polymerase family A (pol I) signature 836 852 1.1E-77 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_3183 5658630072e701b739b2ba3949128691 919 PRINTS PR00868 DNA-polymerase family A (pol I) signature 745 770 1.1E-77 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_3183 5658630072e701b739b2ba3949128691 919 PRINTS PR00868 DNA-polymerase family A (pol I) signature 691 714 1.1E-77 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_3183 5658630072e701b739b2ba3949128691 919 PRINTS PR00868 DNA-polymerase family A (pol I) signature 646 668 1.1E-77 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_3183 5658630072e701b739b2ba3949128691 919 PRINTS PR00868 DNA-polymerase family A (pol I) signature 866 879 1.1E-77 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_3183 5658630072e701b739b2ba3949128691 919 PRINTS PR00868 DNA-polymerase family A (pol I) signature 782 793 1.1E-77 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_3183 5658630072e701b739b2ba3949128691 919 PRINTS PR00868 DNA-polymerase family A (pol I) signature 804 815 1.1E-77 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_3183 5658630072e701b739b2ba3949128691 919 PRINTS PR00868 DNA-polymerase family A (pol I) signature 669 684 1.1E-77 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_3183 5658630072e701b739b2ba3949128691 919 SMART SM00475 1 256 1.8E-116 T 14-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 Tharo_3183 5658630072e701b739b2ba3949128691 919 SMART SM00474 322 508 1.2E-34 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 Tharo_3183 5658630072e701b739b2ba3949128691 919 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 4 165 4.4E-49 T 14-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 Tharo_3183 5658630072e701b739b2ba3949128691 919 Gene3D G3DSA:3.40.50.1010 4 272 1.4E-88 T 14-10-2018 Tharo_3183 5658630072e701b739b2ba3949128691 919 Gene3D G3DSA:3.30.420.10 320 533 1.7E-65 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_3183 5658630072e701b739b2ba3949128691 919 Pfam PF01612 3'-5' exonuclease 327 508 1.8E-35 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 Tharo_3183 5658630072e701b739b2ba3949128691 919 Gene3D G3DSA:3.30.70.370 655 915 1.2E-108 T 14-10-2018 Tharo_3183 5658630072e701b739b2ba3949128691 919 SMART SM00482 677 883 3.2E-114 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_3183 5658630072e701b739b2ba3949128691 919 SMART SM00279 168 203 8.0E-13 T 14-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 Tharo_3183 5658630072e701b739b2ba3949128691 919 Gene3D G3DSA:1.10.150.20 700 843 1.2E-108 T 14-10-2018 Tharo_3183 5658630072e701b739b2ba3949128691 919 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 166 259 4.3E-26 T 14-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 Tharo_1479 136a4e6c1f63086fe4892b18f63c67df 107 Gene3D G3DSA:1.20.1300.10 1 107 2.6E-34 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_1479 136a4e6c1f63086fe4892b18f63c67df 107 SUPERFAMILY SSF81343 3 107 3.92E-27 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_1479 136a4e6c1f63086fe4892b18f63c67df 107 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 3 104 4.0E-34 T 14-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_1479 136a4e6c1f63086fe4892b18f63c67df 107 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 3 102 8.2E-26 T 14-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_1479 136a4e6c1f63086fe4892b18f63c67df 107 PIRSF PIRSF000178 1 107 1.3E-23 T 14-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_2527 c0c9ec4810591829f7014191bd427cd2 246 Pfam PF00005 ABC transporter 24 165 2.4E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_2527 c0c9ec4810591829f7014191bd427cd2 246 Gene3D G3DSA:3.40.50.300 8 241 1.4E-63 T 14-10-2018 Tharo_2527 c0c9ec4810591829f7014191bd427cd2 246 SUPERFAMILY SSF52540 8 228 3.55E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2527 c0c9ec4810591829f7014191bd427cd2 246 SMART SM00382 32 224 5.8E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2527 c0c9ec4810591829f7014191bd427cd2 246 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_0095 7189fd8ca3a5833207d74f2261bf111e 324 Pfam PF08223 PaaX-like protein C-terminal domain 186 281 6.7E-32 T 14-10-2018 IPR013225 PaaX-like, C-terminal Tharo_0095 7189fd8ca3a5833207d74f2261bf111e 324 SUPERFAMILY SSF46785 48 112 1.14E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0095 7189fd8ca3a5833207d74f2261bf111e 324 PIRSF PIRSF020623 1 307 9.2E-103 T 14-10-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 Tharo_0095 7189fd8ca3a5833207d74f2261bf111e 324 Gene3D G3DSA:1.10.10.10 19 102 1.8E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0095 7189fd8ca3a5833207d74f2261bf111e 324 Pfam PF07848 PaaX-like protein 21 87 1.4E-24 T 14-10-2018 IPR012906 PaaX-like, N-terminal Tharo_0095 7189fd8ca3a5833207d74f2261bf111e 324 TIGRFAM TIGR02277 PaaX_trns_reg: phenylacetic acid degradation operon negative regulatory protein PaaX 23 304 1.4E-87 T 14-10-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 Tharo_2230 4d8d7cccdaa996e3d5472f5dcda81b23 658 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 215 259 4.8E-6 T 14-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 Tharo_2230 4d8d7cccdaa996e3d5472f5dcda81b23 658 Gene3D G3DSA:3.40.50.1820 209 463 4.3E-29 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_2230 4d8d7cccdaa996e3d5472f5dcda81b23 658 SUPERFAMILY SSF53474 156 454 1.91E-23 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_0052 c7d09b28d2a25f5a3fe0f3116617aed8 163 SUPERFAMILY SSF52833 2 160 4.7E-42 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_0052 c7d09b28d2a25f5a3fe0f3116617aed8 163 ProSitePatterns PS01265 Tpx family signature. 80 91 - T 14-10-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 KEGG: 00480+1.11.1.15 Tharo_0052 c7d09b28d2a25f5a3fe0f3116617aed8 163 Hamap MF_00269 Thiol peroxidase [tpx]. 1 163 36.255 T 14-10-2018 IPR002065 Thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 KEGG: 00480+1.11.1.15 Tharo_0052 c7d09b28d2a25f5a3fe0f3116617aed8 163 Pfam PF08534 Redoxin 17 159 3.0E-28 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 Tharo_0052 c7d09b28d2a25f5a3fe0f3116617aed8 163 Gene3D G3DSA:3.40.30.10 1 163 3.1E-47 T 14-10-2018 Tharo_0287 50eec92ff812b6b74b0acc0f277640e6 282 SUPERFAMILY SSF51419 30 261 3.27E-75 T 14-10-2018 IPR029066 PLP-binding barrel Tharo_0287 50eec92ff812b6b74b0acc0f277640e6 282 PIRSF PIRSF004848 26 269 1.9E-69 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 Tharo_0287 50eec92ff812b6b74b0acc0f277640e6 282 Pfam PF01168 Alanine racemase, N-terminal domain 40 263 2.4E-24 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Tharo_0287 50eec92ff812b6b74b0acc0f277640e6 282 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 36 263 1.8E-57 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 Tharo_0287 50eec92ff812b6b74b0acc0f277640e6 282 Gene3D G3DSA:3.20.20.10 21 274 6.0E-86 T 14-10-2018 IPR029066 PLP-binding barrel Tharo_0287 50eec92ff812b6b74b0acc0f277640e6 282 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 39 262 28.96 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 Tharo_0745 fece20afd6493d2c7a8c606f959d4634 346 Pfam PF00591 Glycosyl transferase family, a/b domain 78 328 5.6E-96 T 14-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0745 fece20afd6493d2c7a8c606f959d4634 346 Pfam PF02885 Glycosyl transferase family, helical bundle domain 7 66 4.3E-11 T 14-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0745 fece20afd6493d2c7a8c606f959d4634 346 Gene3D G3DSA:3.40.1030.10 76 345 7.8E-110 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0745 fece20afd6493d2c7a8c606f959d4634 346 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 9 337 1.9E-127 T 14-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 Tharo_0745 fece20afd6493d2c7a8c606f959d4634 346 Gene3D G3DSA:1.20.970.10 1 72 8.1E-31 T 14-10-2018 Tharo_0745 fece20afd6493d2c7a8c606f959d4634 346 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 7 338 37.647 T 14-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 Tharo_0745 fece20afd6493d2c7a8c606f959d4634 346 SUPERFAMILY SSF47648 3 71 7.59E-17 T 14-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0745 fece20afd6493d2c7a8c606f959d4634 346 SUPERFAMILY SSF52418 78 341 1.14E-98 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0500 32c1ca47848362965d2d89e1a5268170 128 Pfam PF01250 Ribosomal protein S6 3 91 1.4E-27 T 14-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_0500 32c1ca47848362965d2d89e1a5268170 128 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 22.143 T 14-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 Tharo_0500 32c1ca47848362965d2d89e1a5268170 128 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 1.9E-33 T 14-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_0500 32c1ca47848362965d2d89e1a5268170 128 Gene3D G3DSA:3.30.70.60 1 92 4.5E-33 T 14-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 Tharo_0500 32c1ca47848362965d2d89e1a5268170 128 SUPERFAMILY SSF54995 1 104 6.67E-39 T 14-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_0120 ac44d8aef73c012064ae128a6bd93059 290 SUPERFAMILY SSF54427 165 290 1.01E-11 T 14-10-2018 IPR032710 NTF2-like domain superfamily Tharo_0120 ac44d8aef73c012064ae128a6bd93059 290 Pfam PF04280 Tim44-like domain 164 288 6.1E-15 T 14-10-2018 IPR007379 Tim44-like domain Tharo_0120 ac44d8aef73c012064ae128a6bd93059 290 SMART SM00978 157 288 6.0E-40 T 14-10-2018 IPR007379 Tim44-like domain Tharo_1700 df69c5d380ee64f1764a95358815b7dd 177 SUPERFAMILY SSF54523 4 89 5.96E-16 T 14-10-2018 Tharo_1700 df69c5d380ee64f1764a95358815b7dd 177 Pfam PF07963 Prokaryotic N-terminal methylation motif 3 23 7.8E-5 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Tharo_1700 df69c5d380ee64f1764a95358815b7dd 177 Pfam PF12019 Type II transport protein GspH 42 158 7.3E-11 T 14-10-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 Tharo_1700 df69c5d380ee64f1764a95358815b7dd 177 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 2 24 1.3E-5 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Tharo_1700 df69c5d380ee64f1764a95358815b7dd 177 Gene3D G3DSA:3.30.700.10 4 163 4.4E-14 T 14-10-2018 Tharo_0024 6f982997d1172edbe684a35a32ac2c62 392 Pfam PF07690 Major Facilitator Superfamily 251 389 9.7E-14 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_0024 6f982997d1172edbe684a35a32ac2c62 392 Pfam PF07690 Major Facilitator Superfamily 6 246 1.1E-11 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_0024 6f982997d1172edbe684a35a32ac2c62 392 SUPERFAMILY SSF103473 2 388 1.18E-38 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_0024 6f982997d1172edbe684a35a32ac2c62 392 Gene3D G3DSA:1.20.1250.20 1 383 2.0E-32 T 14-10-2018 Tharo_2972 28372eb8c8547673e27e17f410a9d563 315 Pfam PF02603 HPr Serine kinase N terminus 6 127 1.0E-16 T 14-10-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 Tharo_2972 28372eb8c8547673e27e17f410a9d563 315 Pfam PF07475 HPr Serine kinase C-terminal domain 132 301 1.5E-62 T 14-10-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 Tharo_2972 28372eb8c8547673e27e17f410a9d563 315 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 5 305 7.3E-93 T 14-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 Tharo_2972 28372eb8c8547673e27e17f410a9d563 315 SUPERFAMILY SSF75138 1 133 1.96E-26 T 14-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily Tharo_2972 28372eb8c8547673e27e17f410a9d563 315 SUPERFAMILY SSF53795 134 301 3.36E-36 T 14-10-2018 Tharo_2972 28372eb8c8547673e27e17f410a9d563 315 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 3 308 33.693 T 14-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 Tharo_2972 28372eb8c8547673e27e17f410a9d563 315 Gene3D G3DSA:3.40.50.300 133 310 1.4E-64 T 14-10-2018 Tharo_2972 28372eb8c8547673e27e17f410a9d563 315 Gene3D G3DSA:3.40.1390.20 9 132 2.5E-16 T 14-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily Tharo_2972 28372eb8c8547673e27e17f410a9d563 315 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 151 164 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Tharo_0823 711cf472df4e2c9164673942fcc251a3 358 PIRSF PIRSF019169 4 357 3.0E-123 T 14-10-2018 IPR005883 Type IV pilus assembly protein PilM Tharo_0823 711cf472df4e2c9164673942fcc251a3 358 SUPERFAMILY SSF53067 194 354 1.22E-25 T 14-10-2018 Tharo_0823 711cf472df4e2c9164673942fcc251a3 358 Gene3D G3DSA:3.30.1490.300 91 150 1.3E-87 T 14-10-2018 Tharo_0823 711cf472df4e2c9164673942fcc251a3 358 Gene3D G3DSA:3.30.420.40 16 354 1.3E-87 T 14-10-2018 Tharo_0823 711cf472df4e2c9164673942fcc251a3 358 SUPERFAMILY SSF53067 63 178 1.94E-11 T 14-10-2018 Tharo_0823 711cf472df4e2c9164673942fcc251a3 358 Gene3D G3DSA:3.30.420.40 193 320 1.3E-87 T 14-10-2018 Tharo_0823 711cf472df4e2c9164673942fcc251a3 358 SMART SM00842 14 182 0.0027 T 14-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 Tharo_0823 711cf472df4e2c9164673942fcc251a3 358 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 14 356 1.9E-96 T 14-10-2018 IPR005883 Type IV pilus assembly protein PilM Tharo_0823 711cf472df4e2c9164673942fcc251a3 358 Pfam PF11104 Type IV pilus assembly protein PilM; 16 356 4.9E-137 T 14-10-2018 IPR005883 Type IV pilus assembly protein PilM Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 SUPERFAMILY SSF82866 788 1012 3.27E-51 T 14-10-2018 Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 Gene3D G3DSA:3.30.70.1440 651 846 0.0 T 14-10-2018 Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 SUPERFAMILY SSF82714 182 267 4.71E-17 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 Gene3D G3DSA:3.30.70.1320 134 328 0.0 T 14-10-2018 Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 Gene3D G3DSA:1.20.1640.10 504 1005 0.0 T 14-10-2018 Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 SUPERFAMILY SSF82693 556 650 1.94E-20 T 14-10-2018 Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 Gene3D G3DSA:1.20.1640.10 10 503 0.0 T 14-10-2018 Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 Gene3D G3DSA:3.30.2090.10 701 789 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 SUPERFAMILY SSF82693 40 134 1.2E-24 T 14-10-2018 Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 SUPERFAMILY SSF82714 702 785 3.4E-20 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 SUPERFAMILY SSF82866 304 493 1.7E-47 T 14-10-2018 Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 Gene3D G3DSA:3.30.70.1430 40 797 0.0 T 14-10-2018 Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 PRINTS PR00702 Acriflavin resistance protein family signature 465 488 6.9E-78 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 PRINTS PR00702 Acriflavin resistance protein family signature 359 380 6.9E-78 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 6.9E-78 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 PRINTS PR00702 Acriflavin resistance protein family signature 543 560 6.9E-78 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 6.9E-78 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 PRINTS PR00702 Acriflavin resistance protein family signature 387 411 6.9E-78 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 PRINTS PR00702 Acriflavin resistance protein family signature 440 463 6.9E-78 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 PRINTS PR00702 Acriflavin resistance protein family signature 332 355 6.9E-78 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 PRINTS PR00702 Acriflavin resistance protein family signature 606 620 6.9E-78 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 SUPERFAMILY SSF82693 136 326 9.94E-19 T 14-10-2018 Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 Gene3D G3DSA:3.30.70.1430 558 650 0.0 T 14-10-2018 Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 Pfam PF00873 AcrB/AcrD/AcrF family 4 1008 2.1E-302 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_1074 b50780368d2b90f74514ab024a8d070c 1024 Gene3D G3DSA:3.30.2090.10 178 271 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_2966 66c69ce1cb10ec4241f77cee1d966601 344 Gene3D G3DSA:3.40.50.300 26 269 1.7E-82 T 14-10-2018 Tharo_2966 66c69ce1cb10ec4241f77cee1d966601 344 SUPERFAMILY SSF52540 4 268 7.09E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2966 66c69ce1cb10ec4241f77cee1d966601 344 ProSitePatterns PS00321 recA signature. 214 222 - T 14-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 Tharo_2966 66c69ce1cb10ec4241f77cee1d966601 344 Hamap MF_00268 Protein RecA [recA]. 5 330 51.624 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Tharo_2966 66c69ce1cb10ec4241f77cee1d966601 344 SMART SM00382 58 229 4.7E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2966 66c69ce1cb10ec4241f77cee1d966601 344 PRINTS PR00142 RecA protein signature 298 315 3.8E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Tharo_2966 66c69ce1cb10ec4241f77cee1d966601 344 PRINTS PR00142 RecA protein signature 128 157 3.8E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Tharo_2966 66c69ce1cb10ec4241f77cee1d966601 344 PRINTS PR00142 RecA protein signature 244 273 3.8E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Tharo_2966 66c69ce1cb10ec4241f77cee1d966601 344 PRINTS PR00142 RecA protein signature 211 239 3.8E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Tharo_2966 66c69ce1cb10ec4241f77cee1d966601 344 PRINTS PR00142 RecA protein signature 166 195 3.8E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Tharo_2966 66c69ce1cb10ec4241f77cee1d966601 344 PRINTS PR00142 RecA protein signature 94 123 3.8E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Tharo_2966 66c69ce1cb10ec4241f77cee1d966601 344 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 4 324 3.0E-171 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Tharo_2966 66c69ce1cb10ec4241f77cee1d966601 344 Pfam PF00154 recA bacterial DNA recombination protein 7 269 1.3E-143 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Tharo_2966 66c69ce1cb10ec4241f77cee1d966601 344 SUPERFAMILY SSF54752 269 327 2.22E-21 T 14-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal Tharo_2966 66c69ce1cb10ec4241f77cee1d966601 344 Gene3D G3DSA:3.30.250.10 270 343 4.5E-28 T 14-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal Tharo_1691 48ada844a6ae1f529d2cc4a72c6cac07 409 SUPERFAMILY SSF69864 180 404 7.46E-93 T 14-10-2018 Tharo_1691 48ada844a6ae1f529d2cc4a72c6cac07 409 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 120 131 - T 14-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Tharo_1691 48ada844a6ae1f529d2cc4a72c6cac07 409 Gene3D G3DSA:1.20.5.470 381 406 8.8E-9 T 14-10-2018 Tharo_1691 48ada844a6ae1f529d2cc4a72c6cac07 409 Gene3D G3DSA:3.90.1260.10 67 360 2.2E-155 T 14-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Tharo_1691 48ada844a6ae1f529d2cc4a72c6cac07 409 TIGRFAM TIGR00032 argG: argininosuccinate synthase 6 401 2.5E-140 T 14-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Tharo_1691 48ada844a6ae1f529d2cc4a72c6cac07 409 Hamap MF_00005 Argininosuccinate synthase [argG]. 4 406 50.862 T 14-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Tharo_1691 48ada844a6ae1f529d2cc4a72c6cac07 409 SUPERFAMILY SSF52402 5 170 1.5E-46 T 14-10-2018 Tharo_1691 48ada844a6ae1f529d2cc4a72c6cac07 409 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 10 18 - T 14-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Tharo_1691 48ada844a6ae1f529d2cc4a72c6cac07 409 Gene3D G3DSA:3.40.50.620 7 179 2.2E-155 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_1691 48ada844a6ae1f529d2cc4a72c6cac07 409 Pfam PF00764 Arginosuccinate synthase 8 401 1.9E-151 T 14-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Tharo_3045 ef3292ae15a222381542edf220efbd42 435 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 4 331 3.0E-90 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Tharo_3045 ef3292ae15a222381542edf220efbd42 435 SUPERFAMILY SSF160113 351 399 1.24E-8 T 14-10-2018 IPR036913 YegP-like superfamily Tharo_3045 ef3292ae15a222381542edf220efbd42 435 Pfam PF00579 tRNA synthetases class I (W and Y) 5 283 3.1E-53 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_3045 ef3292ae15a222381542edf220efbd42 435 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 151 172 3.2E-17 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Tharo_3045 ef3292ae15a222381542edf220efbd42 435 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 3.2E-17 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Tharo_3045 ef3292ae15a222381542edf220efbd42 435 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 68 87 3.2E-17 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Tharo_3045 ef3292ae15a222381542edf220efbd42 435 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 202 212 3.2E-17 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Tharo_3045 ef3292ae15a222381542edf220efbd42 435 Gene3D G3DSA:1.10.240.10 197 299 1.2E-110 T 14-10-2018 Tharo_3045 ef3292ae15a222381542edf220efbd42 435 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 21 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_3045 ef3292ae15a222381542edf220efbd42 435 Gene3D G3DSA:3.40.50.620 5 331 1.2E-110 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_3045 ef3292ae15a222381542edf220efbd42 435 SUPERFAMILY SSF52374 4 331 2.29E-82 T 14-10-2018 Tharo_3045 ef3292ae15a222381542edf220efbd42 435 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 3 332 36.3 T 14-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 Tharo_2077 29019859a4b74d5dccb3261b648a7728 273 Gene3D G3DSA:2.160.10.10 87 257 1.5E-55 T 14-10-2018 Tharo_2077 29019859a4b74d5dccb3261b648a7728 273 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 1 272 55.944 T 14-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 Tharo_2077 29019859a4b74d5dccb3261b648a7728 273 Gene3D G3DSA:1.10.166.10 1 70 1.1E-29 T 14-10-2018 IPR037133 Tetrahydrodipicolinate-N-succinyltransferase, N-terminal domain superfamily KEGG: 00300+2.3.1.117 Tharo_2077 29019859a4b74d5dccb3261b648a7728 273 SUPERFAMILY SSF51161 2 256 3.05E-73 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily Tharo_2077 29019859a4b74d5dccb3261b648a7728 273 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 115 166 7.6E-4 T 14-10-2018 IPR001451 Hexapeptide repeat Tharo_2077 29019859a4b74d5dccb3261b648a7728 273 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 4 69 9.0E-27 T 14-10-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 Tharo_2077 29019859a4b74d5dccb3261b648a7728 273 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 175 209 2.3E-12 T 14-10-2018 IPR001451 Hexapeptide repeat Tharo_2077 29019859a4b74d5dccb3261b648a7728 273 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 134 162 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 Tharo_2077 29019859a4b74d5dccb3261b648a7728 273 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 4 272 2.6E-144 T 14-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 Tharo_1080 09415719ffe6d5a523f33ebbff257a4b 637 Pfam PF08676 MutL C terminal dimerisation domain 447 593 1.1E-46 T 14-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 Tharo_1080 09415719ffe6d5a523f33ebbff257a4b 637 SUPERFAMILY SSF55874 3 199 2.1E-50 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1080 09415719ffe6d5a523f33ebbff257a4b 637 Gene3D G3DSA:3.30.230.10 210 322 2.8E-37 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Tharo_1080 09415719ffe6d5a523f33ebbff257a4b 637 Gene3D G3DSA:2.30.42.20 453 630 1.6E-56 T 14-10-2018 Tharo_1080 09415719ffe6d5a523f33ebbff257a4b 637 SMART SM01340 205 323 1.3E-58 T 14-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 Tharo_1080 09415719ffe6d5a523f33ebbff257a4b 637 Gene3D G3DSA:3.30.1370.100 493 588 1.6E-56 T 14-10-2018 Tharo_1080 09415719ffe6d5a523f33ebbff257a4b 637 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 206 322 7.4E-38 T 14-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 Tharo_1080 09415719ffe6d5a523f33ebbff257a4b 637 Gene3D G3DSA:3.30.565.10 2 203 1.9E-61 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1080 09415719ffe6d5a523f33ebbff257a4b 637 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 126 3.6E-11 T 14-10-2018 Tharo_1080 09415719ffe6d5a523f33ebbff257a4b 637 SUPERFAMILY SSF118116 447 635 3.79E-58 T 14-10-2018 IPR037198 MutL, C-terminal domain superfamily Tharo_1080 09415719ffe6d5a523f33ebbff257a4b 637 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 303 7.1E-90 T 14-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 Tharo_1080 09415719ffe6d5a523f33ebbff257a4b 637 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 14-10-2018 IPR014762 DNA mismatch repair, conserved site Tharo_1080 09415719ffe6d5a523f33ebbff257a4b 637 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 633 27.506 T 14-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 Tharo_1080 09415719ffe6d5a523f33ebbff257a4b 637 SMART SM00853 451 593 1.1E-51 T 14-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 Tharo_1080 09415719ffe6d5a523f33ebbff257a4b 637 SUPERFAMILY SSF54211 188 323 6.83E-38 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_1621 0244dc464cfffe5390b40e85d754478e 126 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 86 1.0E-27 T 14-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 Tharo_1621 0244dc464cfffe5390b40e85d754478e 126 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 119 1.6E-18 T 14-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 Tharo_1621 0244dc464cfffe5390b40e85d754478e 126 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 124 22.99 T 14-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 Tharo_1621 0244dc464cfffe5390b40e85d754478e 126 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 124 1.3E-29 T 14-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 Tharo_1621 0244dc464cfffe5390b40e85d754478e 126 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 1 124 7.6E-24 T 14-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 Tharo_1621 0244dc464cfffe5390b40e85d754478e 126 SUPERFAMILY SSF56214 1 123 4.84E-28 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 Tharo_1621 0244dc464cfffe5390b40e85d754478e 126 Gene3D G3DSA:3.90.470.20 1 124 4.5E-34 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 Tharo_2739 b0903c6080c566fe184e160ea11dad51 396 Gene3D G3DSA:2.40.30.10 208 336 4.9E-54 T 14-10-2018 Tharo_2739 b0903c6080c566fe184e160ea11dad51 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 3.8E-234 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Tharo_2739 b0903c6080c566fe184e160ea11dad51 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site Tharo_2739 b0903c6080c566fe184e160ea11dad51 396 SUPERFAMILY SSF50465 304 396 6.91E-36 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal Tharo_2739 b0903c6080c566fe184e160ea11dad51 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 7.6E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2739 b0903c6080c566fe184e160ea11dad51 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 7.6E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2739 b0903c6080c566fe184e160ea11dad51 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 7.6E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2739 b0903c6080c566fe184e160ea11dad51 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 7.6E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2739 b0903c6080c566fe184e160ea11dad51 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 7.6E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2739 b0903c6080c566fe184e160ea11dad51 396 SUPERFAMILY SSF50447 207 303 1.45E-31 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Tharo_2739 b0903c6080c566fe184e160ea11dad51 396 SUPERFAMILY SSF52540 5 221 4.53E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2739 b0903c6080c566fe184e160ea11dad51 396 Gene3D G3DSA:2.40.30.10 340 395 5.4E-29 T 14-10-2018 Tharo_2739 b0903c6080c566fe184e160ea11dad51 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 2.1E-32 T 14-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal Tharo_2739 b0903c6080c566fe184e160ea11dad51 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 4.8E-16 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Tharo_2739 b0903c6080c566fe184e160ea11dad51 396 Pfam PF03144 Elongation factor Tu domain 2 227 296 2.4E-17 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Tharo_2739 b0903c6080c566fe184e160ea11dad51 396 Gene3D G3DSA:3.40.50.300 1 205 1.3E-70 T 14-10-2018 Tharo_2739 b0903c6080c566fe184e160ea11dad51 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.995 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Tharo_2739 b0903c6080c566fe184e160ea11dad51 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.6E-59 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2726 b0903c6080c566fe184e160ea11dad51 396 Gene3D G3DSA:2.40.30.10 208 336 4.9E-54 T 14-10-2018 Tharo_2726 b0903c6080c566fe184e160ea11dad51 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 3.8E-234 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Tharo_2726 b0903c6080c566fe184e160ea11dad51 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site Tharo_2726 b0903c6080c566fe184e160ea11dad51 396 SUPERFAMILY SSF50465 304 396 6.91E-36 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal Tharo_2726 b0903c6080c566fe184e160ea11dad51 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 7.6E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2726 b0903c6080c566fe184e160ea11dad51 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 7.6E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2726 b0903c6080c566fe184e160ea11dad51 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 7.6E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2726 b0903c6080c566fe184e160ea11dad51 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 7.6E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2726 b0903c6080c566fe184e160ea11dad51 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 7.6E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2726 b0903c6080c566fe184e160ea11dad51 396 SUPERFAMILY SSF50447 207 303 1.45E-31 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Tharo_2726 b0903c6080c566fe184e160ea11dad51 396 SUPERFAMILY SSF52540 5 221 4.53E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2726 b0903c6080c566fe184e160ea11dad51 396 Gene3D G3DSA:2.40.30.10 340 395 5.4E-29 T 14-10-2018 Tharo_2726 b0903c6080c566fe184e160ea11dad51 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 2.1E-32 T 14-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal Tharo_2726 b0903c6080c566fe184e160ea11dad51 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 4.8E-16 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Tharo_2726 b0903c6080c566fe184e160ea11dad51 396 Pfam PF03144 Elongation factor Tu domain 2 227 296 2.4E-17 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Tharo_2726 b0903c6080c566fe184e160ea11dad51 396 Gene3D G3DSA:3.40.50.300 1 205 1.3E-70 T 14-10-2018 Tharo_2726 b0903c6080c566fe184e160ea11dad51 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.995 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Tharo_2726 b0903c6080c566fe184e160ea11dad51 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.6E-59 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2038 6022352f0913d71ef863a107c7c11335 394 Gene3D G3DSA:3.40.640.10 57 290 3.1E-131 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_2038 6022352f0913d71ef863a107c7c11335 394 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 20 386 3.3E-137 T 14-10-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 Tharo_2038 6022352f0913d71ef863a107c7c11335 394 Pfam PF00155 Aminotransferase class I and II 42 385 1.4E-54 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Tharo_2038 6022352f0913d71ef863a107c7c11335 394 SUPERFAMILY SSF53383 31 389 9.28E-100 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_2038 6022352f0913d71ef863a107c7c11335 394 Gene3D G3DSA:3.90.1150.10 37 379 3.1E-131 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_2038 6022352f0913d71ef863a107c7c11335 394 Hamap MF_01693 8-amino-7-oxononanoate synthase [bioF]. 3 390 49.714 T 14-10-2018 IPR022834 8-amino-7-oxononanoate synthase, Proteobacteria GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 Tharo_2059 a2d41feb8ffe74fbcbc8f918a4814ad6 786 Gene3D G3DSA:3.10.20.310 20 92 2.3E-21 T 14-10-2018 Tharo_2059 a2d41feb8ffe74fbcbc8f918a4814ad6 786 PIRSF PIRSF006076 2 786 2.1E-258 T 14-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 Tharo_2059 a2d41feb8ffe74fbcbc8f918a4814ad6 786 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 25 786 2.8E-270 T 14-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 Tharo_2059 a2d41feb8ffe74fbcbc8f918a4814ad6 786 Gene3D G3DSA:3.10.20.310 93 173 9.6E-18 T 14-10-2018 Tharo_2059 a2d41feb8ffe74fbcbc8f918a4814ad6 786 Gene3D G3DSA:3.10.20.310 268 344 2.0E-19 T 14-10-2018 Tharo_2059 a2d41feb8ffe74fbcbc8f918a4814ad6 786 Gene3D G3DSA:3.10.20.310 349 425 2.7E-26 T 14-10-2018 Tharo_2059 a2d41feb8ffe74fbcbc8f918a4814ad6 786 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 5 786 25.703 T 14-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 Tharo_2059 a2d41feb8ffe74fbcbc8f918a4814ad6 786 Pfam PF01103 Surface antigen 449 786 8.8E-72 T 14-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 Tharo_2059 a2d41feb8ffe74fbcbc8f918a4814ad6 786 Gene3D G3DSA:3.10.20.310 176 267 3.5E-25 T 14-10-2018 Tharo_2059 a2d41feb8ffe74fbcbc8f918a4814ad6 786 Pfam PF07244 Surface antigen variable number repeat 348 422 1.4E-15 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 Tharo_2059 a2d41feb8ffe74fbcbc8f918a4814ad6 786 Pfam PF07244 Surface antigen variable number repeat 267 345 3.0E-14 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 Tharo_2059 a2d41feb8ffe74fbcbc8f918a4814ad6 786 Pfam PF07244 Surface antigen variable number repeat 94 173 2.0E-12 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 Tharo_2059 a2d41feb8ffe74fbcbc8f918a4814ad6 786 Pfam PF07244 Surface antigen variable number repeat 177 264 1.7E-19 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 Tharo_2059 a2d41feb8ffe74fbcbc8f918a4814ad6 786 Pfam PF07244 Surface antigen variable number repeat 26 92 2.5E-6 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 Tharo_2059 a2d41feb8ffe74fbcbc8f918a4814ad6 786 Gene3D G3DSA:2.40.160.50 426 786 1.3E-111 T 14-10-2018 Tharo_0412 e2671121e67c38c979c7f747a78692a3 203 Pfam PF13417 Glutathione S-transferase, N-terminal domain 5 73 1.1E-16 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 Tharo_0412 e2671121e67c38c979c7f747a78692a3 203 Gene3D G3DSA:3.40.30.10 7 198 6.2E-69 T 14-10-2018 Tharo_0412 e2671121e67c38c979c7f747a78692a3 203 SUPERFAMILY SSF52833 1 99 1.97E-18 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_0412 e2671121e67c38c979c7f747a78692a3 203 SUPERFAMILY SSF47616 70 200 1.53E-23 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily Tharo_0412 e2671121e67c38c979c7f747a78692a3 203 Pfam PF13410 Glutathione S-transferase, C-terminal domain 122 188 2.3E-11 T 14-10-2018 Tharo_0412 e2671121e67c38c979c7f747a78692a3 203 Gene3D G3DSA:1.20.1050.10 79 192 6.2E-69 T 14-10-2018 Tharo_1088 4d5ceb2c6481a49714ce28e7b31d6dce 408 Pfam PF00696 Amino acid kinase family 3 229 8.3E-51 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Tharo_1088 4d5ceb2c6481a49714ce28e7b31d6dce 408 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 403 1.1E-133 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Tharo_1088 4d5ceb2c6481a49714ce28e7b31d6dce 408 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 14-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Tharo_1088 4d5ceb2c6481a49714ce28e7b31d6dce 408 PIRSF PIRSF000726 1 60 5.2E-22 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Tharo_1088 4d5ceb2c6481a49714ce28e7b31d6dce 408 PIRSF PIRSF000726 53 408 7.4E-149 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Tharo_1088 4d5ceb2c6481a49714ce28e7b31d6dce 408 Gene3D G3DSA:3.30.70.260 262 339 6.3E-60 T 14-10-2018 Tharo_1088 4d5ceb2c6481a49714ce28e7b31d6dce 408 Gene3D G3DSA:3.40.1160.10 1 254 1.6E-91 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Tharo_1088 4d5ceb2c6481a49714ce28e7b31d6dce 408 Gene3D G3DSA:3.30.70.260 255 404 6.3E-60 T 14-10-2018 Tharo_1088 4d5ceb2c6481a49714ce28e7b31d6dce 408 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 403 8.8E-119 T 14-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Tharo_1088 4d5ceb2c6481a49714ce28e7b31d6dce 408 SUPERFAMILY SSF53633 4 242 2.62E-74 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Tharo_1088 4d5ceb2c6481a49714ce28e7b31d6dce 408 SUPERFAMILY SSF55021 249 327 1.04E-18 T 14-10-2018 Tharo_1088 4d5ceb2c6481a49714ce28e7b31d6dce 408 SUPERFAMILY SSF55021 331 405 3.27E-25 T 14-10-2018 Tharo_1088 4d5ceb2c6481a49714ce28e7b31d6dce 408 Pfam PF01842 ACT domain 269 324 9.9E-10 T 14-10-2018 IPR002912 ACT domain Tharo_1088 4d5ceb2c6481a49714ce28e7b31d6dce 408 Pfam PF13840 ACT domain 337 400 2.7E-15 T 14-10-2018 IPR027795 CASTOR, ACT domain Tharo_1195 0e69445cf9414bb7733103f4f6a389e2 518 Gene3D G3DSA:3.60.20.10 2 414 5.3E-153 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Tharo_1195 0e69445cf9414bb7733103f4f6a389e2 518 Pfam PF13522 Glutamine amidotransferase domain 65 210 2.4E-15 T 14-10-2018 Tharo_1195 0e69445cf9414bb7733103f4f6a389e2 518 Gene3D G3DSA:3.40.50.2020 279 443 5.3E-153 T 14-10-2018 Tharo_1195 0e69445cf9414bb7733103f4f6a389e2 518 Pfam PF00156 Phosphoribosyl transferase domain 294 395 6.8E-10 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Tharo_1195 0e69445cf9414bb7733103f4f6a389e2 518 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 466 1.9E-160 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 Tharo_1195 0e69445cf9414bb7733103f4f6a389e2 518 PIRSF PIRSF000485 1 483 1.5E-159 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 Tharo_1195 0e69445cf9414bb7733103f4f6a389e2 518 SUPERFAMILY SSF53271 252 483 2.88E-70 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Tharo_1195 0e69445cf9414bb7733103f4f6a389e2 518 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 466 45.489 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 Tharo_1195 0e69445cf9414bb7733103f4f6a389e2 518 SUPERFAMILY SSF56235 2 259 1.29E-68 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Tharo_1921 dac75ab26a6cb1fe8454ad9af5d65b2a 349 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 229 242 - T 14-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1921 dac75ab26a6cb1fe8454ad9af5d65b2a 349 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 17 344 25.003 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1921 dac75ab26a6cb1fe8454ad9af5d65b2a 349 Pfam PF00146 NADH dehydrogenase 24 337 4.1E-126 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1921 dac75ab26a6cb1fe8454ad9af5d65b2a 349 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 63 78 - T 14-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1258 c5525616634172c99c9674f9d8e376a2 449 SUPERFAMILY SSF56801 31 411 2.09E-67 T 14-10-2018 Tharo_1258 c5525616634172c99c9674f9d8e376a2 449 Gene3D G3DSA:3.40.50.12780 9 341 6.9E-144 T 14-10-2018 Tharo_1258 c5525616634172c99c9674f9d8e376a2 449 Pfam PF00501 AMP-binding enzyme 97 302 3.2E-18 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Tharo_1258 c5525616634172c99c9674f9d8e376a2 449 Pfam PF14535 AMP-binding enzyme C-terminal domain 348 446 1.3E-24 T 14-10-2018 IPR028154 AMP-dependent ligase, C-terminal Tharo_1258 c5525616634172c99c9674f9d8e376a2 449 Gene3D G3DSA:3.30.300.30 342 447 8.5E-30 T 14-10-2018 Tharo_1258 c5525616634172c99c9674f9d8e376a2 449 PIRSF PIRSF006444 13 448 8.0E-210 T 14-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 Tharo_1258 c5525616634172c99c9674f9d8e376a2 449 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 24 446 3.2E-234 T 14-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 Tharo_0555 572315978c8b992d38c5fa6b5b4d38c9 192 TIGRFAM TIGR00548 lolB: outer membrane lipoprotein LolB 39 189 2.0E-25 T 14-10-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 Tharo_0555 572315978c8b992d38c5fa6b5b4d38c9 192 SUPERFAMILY SSF89392 19 189 9.42E-38 T 14-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX Tharo_0555 572315978c8b992d38c5fa6b5b4d38c9 192 Hamap MF_00233 Outer-membrane lipoprotein LolB [lolB]. 3 190 20.46 T 14-10-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 Tharo_0555 572315978c8b992d38c5fa6b5b4d38c9 192 Pfam PF03550 Outer membrane lipoprotein LolB 40 188 1.2E-40 T 14-10-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 Tharo_0555 572315978c8b992d38c5fa6b5b4d38c9 192 Gene3D G3DSA:2.50.20.10 25 190 3.1E-38 T 14-10-2018 Tharo_2389 43975ffb2d5258d1d510f4fdd1fcda83 107 Gene3D G3DSA:1.10.10.10 8 101 1.6E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2389 43975ffb2d5258d1d510f4fdd1fcda83 107 SMART SM00418 21 99 9.5E-26 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Tharo_2389 43975ffb2d5258d1d510f4fdd1fcda83 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 53 2.2E-16 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Tharo_2389 43975ffb2d5258d1d510f4fdd1fcda83 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 2.2E-16 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Tharo_2389 43975ffb2d5258d1d510f4fdd1fcda83 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 23 38 2.2E-16 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Tharo_2389 43975ffb2d5258d1d510f4fdd1fcda83 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 2.2E-16 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Tharo_2389 43975ffb2d5258d1d510f4fdd1fcda83 107 SUPERFAMILY SSF46785 12 102 2.46E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_2389 43975ffb2d5258d1d510f4fdd1fcda83 107 Pfam PF01022 Bacterial regulatory protein, arsR family 28 73 6.5E-15 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Tharo_0936 f7574212edf85f10d39b922a87332490 413 Gene3D G3DSA:3.40.50.300 2 250 4.4E-47 T 14-10-2018 Tharo_0936 f7574212edf85f10d39b922a87332490 413 SUPERFAMILY SSF52540 32 232 2.66E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0936 f7574212edf85f10d39b922a87332490 413 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_0936 f7574212edf85f10d39b922a87332490 413 SMART SM00382 48 228 7.1E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0936 f7574212edf85f10d39b922a87332490 413 Gene3D G3DSA:2.70.50.60 254 393 3.2E-16 T 14-10-2018 Tharo_0936 f7574212edf85f10d39b922a87332490 413 Pfam PF14524 Wzt C-terminal domain 260 396 1.0E-36 T 14-10-2018 IPR029439 Wzt, C-terminal Tharo_0936 f7574212edf85f10d39b922a87332490 413 Pfam PF00005 ABC transporter 39 171 2.1E-18 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_2016 0cb8d4edfc10a35c69a7065584b3745e 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 278 6.3E-10 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Tharo_2016 0cb8d4edfc10a35c69a7065584b3745e 281 SUPERFAMILY SSF161098 87 272 2.35E-27 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_2016 0cb8d4edfc10a35c69a7065584b3745e 281 Gene3D G3DSA:1.10.3720.10 84 277 2.6E-27 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_2016 0cb8d4edfc10a35c69a7065584b3745e 281 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 32 278 1.8E-68 T 14-10-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 Tharo_1171 5ae1bbd5dfaeafb8f413ddd711722c8b 108 PRINTS PR00421 Thioredoxin family signature 32 41 7.7E-10 T 14-10-2018 Tharo_1171 5ae1bbd5dfaeafb8f413ddd711722c8b 108 PRINTS PR00421 Thioredoxin family signature 24 32 7.7E-10 T 14-10-2018 Tharo_1171 5ae1bbd5dfaeafb8f413ddd711722c8b 108 PRINTS PR00421 Thioredoxin family signature 72 83 7.7E-10 T 14-10-2018 Tharo_1171 5ae1bbd5dfaeafb8f413ddd711722c8b 108 Pfam PF00085 Thioredoxin 5 106 1.3E-33 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 Tharo_1171 5ae1bbd5dfaeafb8f413ddd711722c8b 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 107 5.6E-39 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Tharo_1171 5ae1bbd5dfaeafb8f413ddd711722c8b 108 Gene3D G3DSA:3.40.30.10 5 108 3.5E-34 T 14-10-2018 Tharo_1171 5ae1bbd5dfaeafb8f413ddd711722c8b 108 PIRSF PIRSF000077 2 108 2.3E-44 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Tharo_1171 5ae1bbd5dfaeafb8f413ddd711722c8b 108 SUPERFAMILY SSF52833 3 107 2.81E-39 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_1171 5ae1bbd5dfaeafb8f413ddd711722c8b 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 Tharo_1851 f7ce2e90a131f5621b571fe772d30a04 800 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 242 797 3.4E-174 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Tharo_1851 f7ce2e90a131f5621b571fe772d30a04 800 SUPERFAMILY SSF81665 242 485 2.88E-16 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 Tharo_1851 f7ce2e90a131f5621b571fe772d30a04 800 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 496 502 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Tharo_1851 f7ce2e90a131f5621b571fe772d30a04 800 Gene3D G3DSA:3.40.50.1000 475 747 1.8E-84 T 14-10-2018 IPR023214 HAD superfamily Tharo_1851 f7ce2e90a131f5621b571fe772d30a04 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 343 357 3.7E-23 T 14-10-2018 Tharo_1851 f7ce2e90a131f5621b571fe772d30a04 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 494 508 3.7E-23 T 14-10-2018 Tharo_1851 f7ce2e90a131f5621b571fe772d30a04 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 718 730 3.7E-23 T 14-10-2018 Tharo_1851 f7ce2e90a131f5621b571fe772d30a04 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 639 649 3.7E-23 T 14-10-2018 Tharo_1851 f7ce2e90a131f5621b571fe772d30a04 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 694 713 3.7E-23 T 14-10-2018 Tharo_1851 f7ce2e90a131f5621b571fe772d30a04 800 SUPERFAMILY SSF81653 295 393 8.63E-22 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Tharo_1851 f7ce2e90a131f5621b571fe772d30a04 800 SUPERFAMILY SSF56784 492 794 1.53E-53 T 14-10-2018 IPR036412 HAD-like superfamily Tharo_1851 f7ce2e90a131f5621b571fe772d30a04 800 Gene3D G3DSA:2.70.150.20 286 397 1.0E-34 T 14-10-2018 Tharo_1851 f7ce2e90a131f5621b571fe772d30a04 800 SUPERFAMILY SSF55008 100 167 6.68E-11 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 Tharo_1851 f7ce2e90a131f5621b571fe772d30a04 800 Gene3D G3DSA:3.40.1110.10 505 624 1.8E-84 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Tharo_1851 f7ce2e90a131f5621b571fe772d30a04 800 Pfam PF00702 haloacid dehalogenase-like hydrolase 492 708 1.1E-41 T 14-10-2018 Tharo_1851 f7ce2e90a131f5621b571fe772d30a04 800 Gene3D G3DSA:3.30.70.100 97 166 1.5E-6 T 14-10-2018 Tharo_1851 f7ce2e90a131f5621b571fe772d30a04 800 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 265 777 2.8E-75 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Tharo_1851 f7ce2e90a131f5621b571fe772d30a04 800 Pfam PF00122 E1-E2 ATPase 293 474 4.1E-54 T 14-10-2018 Tharo_1683 9d8d44265787eacf6ad437fd455374de 554 SUPERFAMILY SSF52540 301 514 2.35E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1683 9d8d44265787eacf6ad437fd455374de 554 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_1683 9d8d44265787eacf6ad437fd455374de 554 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 552 5.5E-285 T 14-10-2018 IPR022374 Energy-dependent translational throttle protein EttA GO:0045900 Tharo_1683 9d8d44265787eacf6ad437fd455374de 554 Pfam PF00005 ABC transporter 23 190 1.4E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_1683 9d8d44265787eacf6ad437fd455374de 554 Gene3D G3DSA:3.40.50.300 1 284 5.6E-81 T 14-10-2018 Tharo_1683 9d8d44265787eacf6ad437fd455374de 554 Pfam PF00005 ABC transporter 339 472 1.0E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_1683 9d8d44265787eacf6ad437fd455374de 554 SUPERFAMILY SSF52540 16 241 3.44E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1683 9d8d44265787eacf6ad437fd455374de 554 SMART SM00382 31 235 2.9E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1683 9d8d44265787eacf6ad437fd455374de 554 SMART SM00382 347 525 1.4E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1683 9d8d44265787eacf6ad437fd455374de 554 Pfam PF12848 ABC transporter 229 305 4.8E-12 T 14-10-2018 IPR032781 ABC-transporter extension domain Tharo_1683 9d8d44265787eacf6ad437fd455374de 554 Gene3D G3DSA:3.40.50.300 285 553 9.5E-72 T 14-10-2018 Tharo_1508 1913f29d612ec642a9a2ed4970f02f03 268 SUPERFAMILY SSF51556 2 252 3.1E-87 T 14-10-2018 IPR032466 Metal-dependent hydrolase Tharo_1508 1913f29d612ec642a9a2ed4970f02f03 268 PIRSF PIRSF005902 1 255 2.2E-77 T 14-10-2018 IPR001130 TatD family GO:0016788 Tharo_1508 1913f29d612ec642a9a2ed4970f02f03 268 Gene3D G3DSA:3.20.20.140 1 257 1.1E-91 T 14-10-2018 Tharo_1508 1913f29d612ec642a9a2ed4970f02f03 268 Pfam PF01026 TatD related DNase 3 251 1.2E-79 T 14-10-2018 IPR001130 TatD family GO:0016788 Tharo_1508 1913f29d612ec642a9a2ed4970f02f03 268 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 14-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 Tharo_1508 1913f29d612ec642a9a2ed4970f02f03 268 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 252 1.4E-85 T 14-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 Tharo_1508 1913f29d612ec642a9a2ed4970f02f03 268 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 188 204 - T 14-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 Tharo_1899 001d2d8120ab6c384c3d15ca9804164d 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 100 114 4.1E-13 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_1899 001d2d8120ab6c384c3d15ca9804164d 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 179 198 4.1E-13 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_1899 001d2d8120ab6c384c3d15ca9804164d 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 239 254 4.1E-13 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_1899 001d2d8120ab6c384c3d15ca9804164d 450 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 101 110 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_1899 001d2d8120ab6c384c3d15ca9804164d 450 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 139 2.7E-40 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_1899 001d2d8120ab6c384c3d15ca9804164d 450 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 263 370 2.4E-32 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_1899 001d2d8120ab6c384c3d15ca9804164d 450 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 162 259 1.9E-19 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_1899 001d2d8120ab6c384c3d15ca9804164d 450 SUPERFAMILY SSF53738 2 186 5.49E-46 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_1899 001d2d8120ab6c384c3d15ca9804164d 450 Gene3D G3DSA:3.40.120.10 262 343 9.4E-62 T 14-10-2018 Tharo_1899 001d2d8120ab6c384c3d15ca9804164d 450 Gene3D G3DSA:3.40.120.10 179 365 9.4E-62 T 14-10-2018 Tharo_1899 001d2d8120ab6c384c3d15ca9804164d 450 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 6 446 1.5E-184 T 14-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_1899 001d2d8120ab6c384c3d15ca9804164d 450 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 377 445 7.4E-16 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_1899 001d2d8120ab6c384c3d15ca9804164d 450 Gene3D G3DSA:3.40.120.10 3 159 4.1E-47 T 14-10-2018 Tharo_1899 001d2d8120ab6c384c3d15ca9804164d 450 SUPERFAMILY SSF53738 263 370 3.92E-32 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_1899 001d2d8120ab6c384c3d15ca9804164d 450 SUPERFAMILY SSF53738 161 261 4.32E-29 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_1899 001d2d8120ab6c384c3d15ca9804164d 450 Gene3D G3DSA:3.30.310.50 374 450 6.8E-22 T 14-10-2018 Tharo_1899 001d2d8120ab6c384c3d15ca9804164d 450 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 2 448 47.505 T 14-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_1899 001d2d8120ab6c384c3d15ca9804164d 450 SUPERFAMILY SSF55957 362 449 6.54E-22 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 SUPERFAMILY SSF81653 269 367 3.79E-27 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 Pfam PF00702 haloacid dehalogenase-like hydrolase 465 682 3.9E-37 T 14-10-2018 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 SUPERFAMILY SSF56784 467 775 3.3E-54 T 14-10-2018 IPR036412 HAD-like superfamily Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 Gene3D G3DSA:3.40.1110.10 480 600 2.0E-86 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 176 777 8.6E-170 T 14-10-2018 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 Pfam PF04945 YHS domain 26 70 6.6E-15 T 14-10-2018 IPR007029 YHS domain Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 668 687 1.1E-28 T 14-10-2018 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 691 703 1.1E-28 T 14-10-2018 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 469 483 1.1E-28 T 14-10-2018 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 593 604 1.1E-28 T 14-10-2018 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 317 331 1.1E-28 T 14-10-2018 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 615 625 1.1E-28 T 14-10-2018 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 194 777 7.2E-180 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 Gene3D G3DSA:3.40.50.1000 450 720 2.0E-86 T 14-10-2018 IPR023214 HAD superfamily Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 SUPERFAMILY SSF81665 235 463 2.22E-12 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 SMART SM00746 27 64 2.0E-9 T 14-10-2018 IPR011017 TRASH domain Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 Pfam PF00122 E1-E2 ATPase 267 448 3.5E-55 T 14-10-2018 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 238 746 5.4E-84 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 Gene3D G3DSA:2.70.150.20 260 372 2.2E-43 T 14-10-2018 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 SUPERFAMILY SSF47240 27 67 6.76E-5 T 14-10-2018 IPR009078 Ferritin-like superfamily Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 PRINTS PR00943 Copper-transporting ATPase signature 702 716 4.7E-16 T 14-10-2018 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 PRINTS PR00943 Copper-transporting ATPase signature 390 404 4.7E-16 T 14-10-2018 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 PRINTS PR00943 Copper-transporting ATPase signature 179 198 4.7E-16 T 14-10-2018 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 PRINTS PR00943 Copper-transporting ATPase signature 452 467 4.7E-16 T 14-10-2018 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 PRINTS PR00943 Copper-transporting ATPase signature 645 662 4.7E-16 T 14-10-2018 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 PRINTS PR00943 Copper-transporting ATPase signature 236 255 4.7E-16 T 14-10-2018 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 PRINTS PR00943 Copper-transporting ATPase signature 741 755 4.7E-16 T 14-10-2018 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 PRINTS PR00943 Copper-transporting ATPase signature 256 274 4.7E-16 T 14-10-2018 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 471 477 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Tharo_2425 c17466fdddb546bd74a48011c7877d96 782 Gene3D G3DSA:1.10.620.20 12 94 6.8E-6 T 14-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 Tharo_2547 673726f82d7c66b36cac50899f5d57c0 537 Pfam PF01642 Methylmalonyl-CoA mutase 15 529 1.3E-187 T 14-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Tharo_2547 673726f82d7c66b36cac50899f5d57c0 537 Gene3D G3DSA:3.20.20.240 1 537 5.0E-213 T 14-10-2018 Tharo_2547 673726f82d7c66b36cac50899f5d57c0 537 SUPERFAMILY SSF51703 3 531 5.23E-180 T 14-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Tharo_2547 673726f82d7c66b36cac50899f5d57c0 537 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 15 536 1.1E-180 T 14-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Tharo_1760 70c291169b3d6749ca0bacbab77a8e9f 92 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 14 83 1.0E-9 T 14-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 Tharo_1265 e040d148b7e476b1772bbddb91f4c6d5 400 TIGRFAM TIGR02430 pcaF: 3-oxoadipyl-CoA thiolase 3 400 6.7E-221 T 14-10-2018 IPR012793 Beta-ketoadipyl CoA thiolase GO:0016747|GO:0019619 KEGG: 00360+2.3.1.174|KEGG: 00362+2.3.1.174|MetaCyc: PWY-1361|MetaCyc: PWY-2361|MetaCyc: PWY-6185 Tharo_1265 e040d148b7e476b1772bbddb91f4c6d5 400 Pfam PF00108 Thiolase, N-terminal domain 4 267 2.6E-69 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 Tharo_1265 e040d148b7e476b1772bbddb91f4c6d5 400 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 Tharo_1265 e040d148b7e476b1772bbddb91f4c6d5 400 SUPERFAMILY SSF53901 1 273 5.76E-79 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_1265 e040d148b7e476b1772bbddb91f4c6d5 400 PIRSF PIRSF000429 1 400 5.9E-132 T 14-10-2018 IPR002155 Thiolase GO:0016747 Tharo_1265 e040d148b7e476b1772bbddb91f4c6d5 400 SUPERFAMILY SSF53901 276 399 8.83E-45 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_1265 e040d148b7e476b1772bbddb91f4c6d5 400 ProSitePatterns PS00099 Thiolases active site. 381 394 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 Tharo_1265 e040d148b7e476b1772bbddb91f4c6d5 400 Gene3D G3DSA:3.40.47.10 141 397 2.2E-152 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_1265 e040d148b7e476b1772bbddb91f4c6d5 400 Pfam PF02803 Thiolase, C-terminal domain 276 399 8.1E-45 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 Tharo_1265 e040d148b7e476b1772bbddb91f4c6d5 400 Gene3D G3DSA:3.40.47.10 6 281 2.2E-152 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_1265 e040d148b7e476b1772bbddb91f4c6d5 400 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 398 3.2E-133 T 14-10-2018 IPR002155 Thiolase GO:0016747 Tharo_1265 e040d148b7e476b1772bbddb91f4c6d5 400 ProSitePatterns PS00737 Thiolases signature 2. 346 362 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 Tharo_1903 059e02de63a02d6d059110711b3cf0b2 260 SUPERFAMILY SSF52540 13 246 5.55E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1903 059e02de63a02d6d059110711b3cf0b2 260 SMART SM00382 36 232 1.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1903 059e02de63a02d6d059110711b3cf0b2 260 Gene3D G3DSA:3.40.50.300 13 258 2.6E-66 T 14-10-2018 Tharo_1903 059e02de63a02d6d059110711b3cf0b2 260 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_1903 059e02de63a02d6d059110711b3cf0b2 260 Pfam PF00005 ABC transporter 27 185 1.1E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_1903 059e02de63a02d6d059110711b3cf0b2 260 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 13 260 5.5E-112 T 14-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 Tharo_1919 d6a22d167d39df9d2c517ad9af1eef22 434 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 44 214 7.3E-45 T 14-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1919 d6a22d167d39df9d2c517ad9af1eef22 434 Pfam PF10531 SLBB domain 238 286 2.3E-14 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1919 d6a22d167d39df9d2c517ad9af1eef22 434 Gene3D G3DSA:3.10.20.600 227 321 6.1E-37 T 14-10-2018 Tharo_1919 d6a22d167d39df9d2c517ad9af1eef22 434 SMART SM00928 324 369 2.8E-24 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1919 d6a22d167d39df9d2c517ad9af1eef22 434 Gene3D G3DSA:3.40.50.11540 48 225 1.8E-76 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1919 d6a22d167d39df9d2c517ad9af1eef22 434 SUPERFAMILY SSF142019 6 234 2.48E-80 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1919 d6a22d167d39df9d2c517ad9af1eef22 434 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 337 348 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1919 d6a22d167d39df9d2c517ad9af1eef22 434 SUPERFAMILY SSF140490 320 418 1.7E-36 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1919 d6a22d167d39df9d2c517ad9af1eef22 434 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 326 409 1.3E-27 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1919 d6a22d167d39df9d2c517ad9af1eef22 434 Gene3D G3DSA:1.20.1440.230 322 422 1.9E-31 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1919 d6a22d167d39df9d2c517ad9af1eef22 434 SUPERFAMILY SSF142984 236 319 1.44E-27 T 14-10-2018 Tharo_1919 d6a22d167d39df9d2c517ad9af1eef22 434 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 7 410 2.7E-193 T 14-10-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_2315 62e37b3e9418cdcc01070a1d4d717587 225 SUPERFAMILY SSF47781 16 88 8.15E-11 T 14-10-2018 IPR010994 RuvA domain 2-like Tharo_2315 62e37b3e9418cdcc01070a1d4d717587 225 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 173 178 - T 14-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site Tharo_2315 62e37b3e9418cdcc01070a1d4d717587 225 Pfam PF04002 RadC-like JAB domain 104 224 8.9E-39 T 14-10-2018 IPR025657 RadC-like JAB domain Tharo_2315 62e37b3e9418cdcc01070a1d4d717587 225 SUPERFAMILY SSF102712 118 189 1.44E-5 T 14-10-2018 Tharo_2315 62e37b3e9418cdcc01070a1d4d717587 225 Gene3D G3DSA:3.40.140.10 101 225 3.8E-37 T 14-10-2018 Tharo_2315 62e37b3e9418cdcc01070a1d4d717587 225 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 225 2.4E-65 T 14-10-2018 IPR001405 Uncharacterised protein family UPF0758 Tharo_2869 40ae55caf92bc9a64529f8596c04e547 134 Pfam PF00114 Pilin (bacterial filament) 37 125 1.7E-6 T 14-10-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 Tharo_2869 40ae55caf92bc9a64529f8596c04e547 134 Gene3D G3DSA:3.30.700.10 8 132 3.1E-29 T 14-10-2018 Tharo_2869 40ae55caf92bc9a64529f8596c04e547 134 SUPERFAMILY SSF54523 8 129 5.23E-23 T 14-10-2018 Tharo_2869 40ae55caf92bc9a64529f8596c04e547 134 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 28 8.0E-11 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Tharo_2869 40ae55caf92bc9a64529f8596c04e547 134 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Tharo_2869 40ae55caf92bc9a64529f8596c04e547 134 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 28 2.4E-10 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Tharo_0821 2f1f4c114f8ed14b505e121035ebabb2 108 Pfam PF01491 Frataxin-like domain 1 101 2.1E-21 T 14-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 Tharo_0821 2f1f4c114f8ed14b505e121035ebabb2 108 SMART SM01219 1 105 7.2E-44 T 14-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 Tharo_0821 2f1f4c114f8ed14b505e121035ebabb2 108 ProSitePatterns PS01344 Frataxin family signature. 49 63 - T 14-10-2018 IPR020895 Frataxin conserved site Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 Tharo_0821 2f1f4c114f8ed14b505e121035ebabb2 108 Hamap MF_00142 Iron-sulfur cluster assembly protein CyaY [cyaY]. 1 104 22.343 T 14-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 Tharo_0821 2f1f4c114f8ed14b505e121035ebabb2 108 Gene3D G3DSA:3.30.920.10 1 105 7.8E-33 T 14-10-2018 IPR036524 Frataxin/CyaY superfamily GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 Tharo_0821 2f1f4c114f8ed14b505e121035ebabb2 108 TIGRFAM TIGR03421 FeS_CyaY: iron donor protein CyaY 3 103 3.6E-33 T 14-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 Tharo_0821 2f1f4c114f8ed14b505e121035ebabb2 108 SUPERFAMILY SSF55387 1 101 7.5E-28 T 14-10-2018 Tharo_2606 72d7cb315002195f8e83f9384cc77fbc 134 Gene3D G3DSA:3.30.160.20 1 134 8.1E-38 T 14-10-2018 Tharo_2606 72d7cb315002195f8e83f9384cc77fbc 134 Pfam PF00472 RF-1 domain 5 129 1.2E-21 T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Tharo_2606 72d7cb315002195f8e83f9384cc77fbc 134 SUPERFAMILY SSF75620 4 101 1.73E-10 T 14-10-2018 Tharo_0328 1b166d3aceda4e0e22053fa8c742cea2 98 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 5 88 1.8E-13 T 14-10-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 Tharo_0328 1b166d3aceda4e0e22053fa8c742cea2 98 SUPERFAMILY SSF101498 31 88 2.22E-8 T 14-10-2018 IPR035890 Anti-sigma-28 factor FlgM superfamily Tharo_0328 1b166d3aceda4e0e22053fa8c742cea2 98 Pfam PF04316 Anti-sigma-28 factor, FlgM 42 86 1.1E-8 T 14-10-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal Tharo_0566 acc80d2384354c34d205b00eb3cd3c42 187 SUPERFAMILY SSF52833 1 186 7.71E-59 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_0566 acc80d2384354c34d205b00eb3cd3c42 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 9.6E-104 T 14-10-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Tharo_0566 acc80d2384354c34d205b00eb3cd3c42 187 Gene3D G3DSA:3.40.30.10 1 186 3.3E-64 T 14-10-2018 Tharo_0566 acc80d2384354c34d205b00eb3cd3c42 187 PIRSF PIRSF000239 1 187 1.1E-53 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Tharo_0566 acc80d2384354c34d205b00eb3cd3c42 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 158 181 3.6E-5 T 14-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Tharo_0566 acc80d2384354c34d205b00eb3cd3c42 187 Pfam PF00578 AhpC/TSA family 5 132 8.5E-35 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Tharo_0325 dd4196cabd91c1ef887612eec3f1e1fe 89 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 4.1E-32 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like Tharo_0325 dd4196cabd91c1ef887612eec3f1e1fe 89 Pfam PF00381 PTS HPr component phosphorylation site 5 82 9.5E-27 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like Tharo_0325 dd4196cabd91c1ef887612eec3f1e1fe 89 Gene3D G3DSA:3.30.1340.10 1 88 1.4E-31 T 14-10-2018 IPR035895 HPr-like superfamily Tharo_0325 dd4196cabd91c1ef887612eec3f1e1fe 89 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 14-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site Tharo_0325 dd4196cabd91c1ef887612eec3f1e1fe 89 PRINTS PR00107 Phosphocarrier protein signature 38 53 6.5E-16 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like Tharo_0325 dd4196cabd91c1ef887612eec3f1e1fe 89 PRINTS PR00107 Phosphocarrier protein signature 53 70 6.5E-16 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like Tharo_0325 dd4196cabd91c1ef887612eec3f1e1fe 89 PRINTS PR00107 Phosphocarrier protein signature 13 29 6.5E-16 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like Tharo_0325 dd4196cabd91c1ef887612eec3f1e1fe 89 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 14-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site Tharo_0325 dd4196cabd91c1ef887612eec3f1e1fe 89 SUPERFAMILY SSF55594 1 88 7.46E-29 T 14-10-2018 IPR035895 HPr-like superfamily Tharo_1811 433aa19e4260e0b75b2af3046742c27e 395 SUPERFAMILY SSF54373 176 276 8.24E-47 T 14-10-2018 Tharo_1811 433aa19e4260e0b75b2af3046742c27e 395 SUPERFAMILY SSF51905 1 391 2.65E-54 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1811 433aa19e4260e0b75b2af3046742c27e 395 TIGRFAM TIGR02360 pbenz_hydroxyl: 4-hydroxybenzoate 3-monooxygenase 1 390 1.9E-194 T 14-10-2018 IPR012733 4-hydroxybenzoate 3-monooxygenase GO:0018659|GO:0043639|GO:0050660|GO:0055114 Tharo_1811 433aa19e4260e0b75b2af3046742c27e 395 Gene3D G3DSA:3.30.9.10 73 387 1.2E-160 T 14-10-2018 Tharo_1811 433aa19e4260e0b75b2af3046742c27e 395 Pfam PF01494 FAD binding domain 3 344 9.5E-85 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 Tharo_1811 433aa19e4260e0b75b2af3046742c27e 395 Gene3D G3DSA:3.50.50.60 2 352 1.2E-160 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1811 433aa19e4260e0b75b2af3046742c27e 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 9.4E-28 T 14-10-2018 Tharo_1811 433aa19e4260e0b75b2af3046742c27e 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 9.4E-28 T 14-10-2018 Tharo_1811 433aa19e4260e0b75b2af3046742c27e 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 9.4E-28 T 14-10-2018 Tharo_1811 433aa19e4260e0b75b2af3046742c27e 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 329 9.4E-28 T 14-10-2018 Tharo_1811 433aa19e4260e0b75b2af3046742c27e 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 9.4E-28 T 14-10-2018 Tharo_2773 a7201d82a6c4bc1f55aab93e3e654cdf 548 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 286 301 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Tharo_2773 a7201d82a6c4bc1f55aab93e3e654cdf 548 SUPERFAMILY SSF52540 199 442 3.68E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2773 a7201d82a6c4bc1f55aab93e3e654cdf 548 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 224 237 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Tharo_2773 a7201d82a6c4bc1f55aab93e3e654cdf 548 SUPERFAMILY SSF111126 17 148 1.52E-8 T 14-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily Tharo_2773 a7201d82a6c4bc1f55aab93e3e654cdf 548 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 413 422 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Tharo_2773 a7201d82a6c4bc1f55aab93e3e654cdf 548 Gene3D G3DSA:1.10.10.60 465 528 4.9E-9 T 14-10-2018 Tharo_2773 a7201d82a6c4bc1f55aab93e3e654cdf 548 Pfam PF06505 Activator of aromatic catabolism 1 80 3.7E-27 T 14-10-2018 IPR010523 Activator of aromatic catabolism Tharo_2773 a7201d82a6c4bc1f55aab93e3e654cdf 548 Pfam PF00158 Sigma-54 interaction domain 200 366 1.3E-65 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Tharo_2773 a7201d82a6c4bc1f55aab93e3e654cdf 548 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 491 508 1.2E-9 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_2773 a7201d82a6c4bc1f55aab93e3e654cdf 548 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 508 528 1.2E-9 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_2773 a7201d82a6c4bc1f55aab93e3e654cdf 548 Pfam PF02954 Bacterial regulatory protein, Fis family 484 525 1.9E-13 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_2773 a7201d82a6c4bc1f55aab93e3e654cdf 548 Pfam PF02830 V4R domain 92 153 1.6E-14 T 14-10-2018 IPR004096 4-vinyl reductase, 4VR Tharo_2773 a7201d82a6c4bc1f55aab93e3e654cdf 548 SMART SM00382 220 363 1.0E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2773 a7201d82a6c4bc1f55aab93e3e654cdf 548 SUPERFAMILY SSF46689 413 525 1.75E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_2773 a7201d82a6c4bc1f55aab93e3e654cdf 548 SMART SM00989 91 153 1.6E-25 T 14-10-2018 IPR004096 4-vinyl reductase, 4VR Tharo_2773 a7201d82a6c4bc1f55aab93e3e654cdf 548 Gene3D G3DSA:3.40.50.300 188 371 1.9E-62 T 14-10-2018 Tharo_2773 a7201d82a6c4bc1f55aab93e3e654cdf 548 ProDom PD485437 REGULATOR TRANSCRIPTIONAL FIS-TYPE HELIX-TURN-HELIX ACTIVATOR PLASMID FAMILY PHENOL-DEGRADATIVE FIS SIGMA-54 1 106 9.0E-46 T 14-10-2018 IPR010523 Activator of aromatic catabolism Tharo_2773 a7201d82a6c4bc1f55aab93e3e654cdf 548 Gene3D G3DSA:1.10.8.60 373 451 1.3E-22 T 14-10-2018 Tharo_1278 6e39e7fd3d739550dcf742b19f62fcb9 478 Gene3D G3DSA:3.40.309.10 254 443 8.1E-167 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Tharo_1278 6e39e7fd3d739550dcf742b19f62fcb9 478 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 Tharo_1278 6e39e7fd3d739550dcf742b19f62fcb9 478 SUPERFAMILY SSF53720 8 474 1.01E-155 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Tharo_1278 6e39e7fd3d739550dcf742b19f62fcb9 478 Pfam PF00171 Aldehyde dehydrogenase family 21 468 1.8E-152 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Tharo_1278 6e39e7fd3d739550dcf742b19f62fcb9 478 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 247 254 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 Tharo_1278 6e39e7fd3d739550dcf742b19f62fcb9 478 Gene3D G3DSA:3.40.605.10 25 469 8.1E-167 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Tharo_2202 7e24941dc3dd6d64e2d91b21ddb74231 183 SUPERFAMILY SSF54862 35 172 4.65E-31 T 14-10-2018 Tharo_2202 7e24941dc3dd6d64e2d91b21ddb74231 183 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 113 124 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_2202 7e24941dc3dd6d64e2d91b21ddb74231 183 PIRSF PIRSF005784 1 183 2.2E-86 T 14-10-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 Tharo_2202 7e24941dc3dd6d64e2d91b21ddb74231 183 Gene3D G3DSA:3.30.70.20 82 178 9.5E-22 T 14-10-2018 Tharo_2202 7e24941dc3dd6d64e2d91b21ddb74231 183 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 143 154 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_2202 7e24941dc3dd6d64e2d91b21ddb74231 183 Hamap MF_00463 Ion-translocating oxidoreductase complex subunit B [rsxB]. 1 165 25.461 T 14-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 Tharo_2202 7e24941dc3dd6d64e2d91b21ddb74231 183 Pfam PF04060 Putative Fe-S cluster 41 73 6.2E-17 T 14-10-2018 IPR007202 4Fe-4S domain GO:0051536 Tharo_2202 7e24941dc3dd6d64e2d91b21ddb74231 183 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 2 182 4.6E-84 T 14-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 Tharo_2202 7e24941dc3dd6d64e2d91b21ddb74231 183 Pfam PF14697 4Fe-4S dicluster domain 106 160 3.0E-17 T 14-10-2018 Tharo_2202 7e24941dc3dd6d64e2d91b21ddb74231 183 Gene3D G3DSA:1.10.15.40 36 81 1.8E-10 T 14-10-2018 Tharo_0057 2a11526c62ddccb912de3504cf9d0518 388 Gene3D G3DSA:1.10.10.10 306 386 4.4E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0057 2a11526c62ddccb912de3504cf9d0518 388 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 72 292 1.5E-74 T 14-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 Tharo_0057 2a11526c62ddccb912de3504cf9d0518 388 Pfam PF02481 DNA recombination-mediator protein A 75 283 1.1E-75 T 14-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 Tharo_0057 2a11526c62ddccb912de3504cf9d0518 388 SUPERFAMILY SSF102405 83 293 5.04E-44 T 14-10-2018 Tharo_0057 2a11526c62ddccb912de3504cf9d0518 388 Gene3D G3DSA:3.40.50.450 1 294 7.1E-106 T 14-10-2018 Tharo_0057 2a11526c62ddccb912de3504cf9d0518 388 SUPERFAMILY SSF47781 6 58 3.5E-5 T 14-10-2018 IPR010994 RuvA domain 2-like Tharo_1720 b9f61d4dacb7646477b7e0341ec7719f 780 Gene3D G3DSA:3.10.105.10 446 693 7.4E-46 T 14-10-2018 Tharo_1720 b9f61d4dacb7646477b7e0341ec7719f 780 SUPERFAMILY SSF53850 67 711 2.35E-87 T 14-10-2018 Tharo_1720 b9f61d4dacb7646477b7e0341ec7719f 780 Gene3D G3DSA:3.40.190.10 309 445 8.2E-13 T 14-10-2018 Tharo_1720 b9f61d4dacb7646477b7e0341ec7719f 780 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 200 636 2.5E-47 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain Tharo_3260 9b304d1c04322337fb485f7c829d1846 595 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_3260 9b304d1c04322337fb485f7c829d1846 595 SMART SM00382 379 566 8.6E-20 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_3260 9b304d1c04322337fb485f7c829d1846 595 Gene3D G3DSA:3.40.50.300 341 592 1.9E-92 T 14-10-2018 Tharo_3260 9b304d1c04322337fb485f7c829d1846 595 Pfam PF00005 ABC transporter 370 520 3.6E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_3260 9b304d1c04322337fb485f7c829d1846 595 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 14 593 3.8E-242 T 14-10-2018 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 Tharo_3260 9b304d1c04322337fb485f7c829d1846 595 SUPERFAMILY SSF52540 342 591 2.55E-92 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3260 9b304d1c04322337fb485f7c829d1846 595 Gene3D G3DSA:1.20.1560.10 3 340 9.5E-75 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Tharo_3260 9b304d1c04322337fb485f7c829d1846 595 SUPERFAMILY SSF90123 17 340 4.32E-70 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Tharo_3260 9b304d1c04322337fb485f7c829d1846 595 Pfam PF00664 ABC transporter transmembrane region 31 303 8.1E-47 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Tharo_0534 0f28434942c1b5b83f8fafcae8b53b44 134 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 50 129 2.9E-16 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0534 0f28434942c1b5b83f8fafcae8b53b44 134 PRINTS PR00607 Class IE cytochrome C signature 104 116 1.0E-11 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 Tharo_0534 0f28434942c1b5b83f8fafcae8b53b44 134 PRINTS PR00607 Class IE cytochrome C signature 61 72 1.0E-11 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 Tharo_0534 0f28434942c1b5b83f8fafcae8b53b44 134 PRINTS PR00607 Class IE cytochrome C signature 72 82 1.0E-11 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 Tharo_0534 0f28434942c1b5b83f8fafcae8b53b44 134 PRINTS PR00607 Class IE cytochrome C signature 119 130 1.0E-11 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 Tharo_0534 0f28434942c1b5b83f8fafcae8b53b44 134 Gene3D G3DSA:1.10.760.10 48 134 9.1E-34 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_0534 0f28434942c1b5b83f8fafcae8b53b44 134 SUPERFAMILY SSF46626 35 131 1.58E-19 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_2542 c5a4d9e7a50190fe9c04b307885518f0 511 Pfam PF13193 AMP-binding enzyme C-terminal domain 416 491 7.7E-19 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Tharo_2542 c5a4d9e7a50190fe9c04b307885518f0 511 SUPERFAMILY SSF56801 3 503 2.35E-152 T 14-10-2018 Tharo_2542 c5a4d9e7a50190fe9c04b307885518f0 511 Pfam PF00501 AMP-binding enzyme 8 407 3.2E-99 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Tharo_2542 c5a4d9e7a50190fe9c04b307885518f0 511 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 14-10-2018 IPR020845 AMP-binding, conserved site Tharo_2542 c5a4d9e7a50190fe9c04b307885518f0 511 Gene3D G3DSA:3.40.50.12780 2 400 1.6E-117 T 14-10-2018 Tharo_2542 c5a4d9e7a50190fe9c04b307885518f0 511 Gene3D G3DSA:3.30.300.310 403 504 2.1E-32 T 14-10-2018 Tharo_2632 5d97626b31b7c9085eeb6a5c945ab494 151 Gene3D G3DSA:2.60.40.1890 26 139 3.1E-38 T 14-10-2018 IPR036182 Copper chaperone PCuAC superfamily Tharo_2632 5d97626b31b7c9085eeb6a5c945ab494 151 SUPERFAMILY SSF110087 4 128 4.84E-45 T 14-10-2018 IPR036182 Copper chaperone PCuAC superfamily Tharo_2632 5d97626b31b7c9085eeb6a5c945ab494 151 Pfam PF04314 Copper chaperone PCu(A)C 23 124 1.7E-36 T 14-10-2018 IPR007410 Copper chaperone PCuAC Tharo_2021 2224fdc4934739decd9f4e890831f2a0 94 SMART SM00530 36 92 1.2E-4 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_2021 2224fdc4934739decd9f4e890831f2a0 94 Pfam PF13744 Helix-turn-helix domain 13 93 2.2E-23 T 14-10-2018 IPR039554 HigA2-like, helix-turn-helix domain Tharo_2021 2224fdc4934739decd9f4e890831f2a0 94 SUPERFAMILY SSF47413 23 92 3.66E-19 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_2021 2224fdc4934739decd9f4e890831f2a0 94 Gene3D G3DSA:1.10.260.40 9 94 2.1E-25 T 14-10-2018 Tharo_0540 3e88bc504b4613e6d10f2b6e6e978967 314 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_0540 3e88bc504b4613e6d10f2b6e6e978967 314 SMART SM00382 40 221 5.7E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0540 3e88bc504b4613e6d10f2b6e6e978967 314 Pfam PF00005 ABC transporter 32 172 7.7E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_0540 3e88bc504b4613e6d10f2b6e6e978967 314 Gene3D G3DSA:3.40.50.300 7 238 2.3E-65 T 14-10-2018 Tharo_0540 3e88bc504b4613e6d10f2b6e6e978967 314 SUPERFAMILY SSF52540 14 235 3.79E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1443 3e88bc504b4613e6d10f2b6e6e978967 314 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_1443 3e88bc504b4613e6d10f2b6e6e978967 314 SMART SM00382 40 221 5.7E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1443 3e88bc504b4613e6d10f2b6e6e978967 314 Pfam PF00005 ABC transporter 32 172 7.7E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_1443 3e88bc504b4613e6d10f2b6e6e978967 314 Gene3D G3DSA:3.40.50.300 7 238 2.3E-65 T 14-10-2018 Tharo_1443 3e88bc504b4613e6d10f2b6e6e978967 314 SUPERFAMILY SSF52540 14 235 3.79E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3092 c5aefccd61fafa4349463e3fdc4b6c49 1257 Pfam PF02607 B12 binding domain 672 749 9.0E-25 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_3092 c5aefccd61fafa4349463e3fdc4b6c49 1257 Pfam PF02574 Homocysteine S-methyltransferase 18 332 6.3E-77 T 14-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 Tharo_3092 c5aefccd61fafa4349463e3fdc4b6c49 1257 Pfam PF00809 Pterin binding enzyme 367 610 1.1E-53 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_3092 c5aefccd61fafa4349463e3fdc4b6c49 1257 Pfam PF02310 B12 binding domain 767 871 4.9E-20 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 Tharo_3092 c5aefccd61fafa4349463e3fdc4b6c49 1257 TIGRFAM TIGR02082 metH: methionine synthase 14 1227 0.0 T 14-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_3092 c5aefccd61fafa4349463e3fdc4b6c49 1257 Gene3D G3DSA:3.40.50.280 763 914 1.7E-55 T 14-10-2018 Tharo_3092 c5aefccd61fafa4349463e3fdc4b6c49 1257 Gene3D G3DSA:3.20.20.20 347 658 1.1E-122 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_3092 c5aefccd61fafa4349463e3fdc4b6c49 1257 SUPERFAMILY SSF47644 665 756 1.44E-26 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_3092 c5aefccd61fafa4349463e3fdc4b6c49 1257 SUPERFAMILY SSF56507 946 1257 5.1E-127 T 14-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_3092 c5aefccd61fafa4349463e3fdc4b6c49 1257 SMART SM01018 670 757 1.9E-42 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_3092 c5aefccd61fafa4349463e3fdc4b6c49 1257 Gene3D G3DSA:3.10.196.10 947 1257 3.2E-134 T 14-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_3092 c5aefccd61fafa4349463e3fdc4b6c49 1257 SUPERFAMILY SSF51717 363 637 8.37E-85 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_3092 c5aefccd61fafa4349463e3fdc4b6c49 1257 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 971 1243 1.1E-122 T 14-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_3092 c5aefccd61fafa4349463e3fdc4b6c49 1257 Gene3D G3DSA:3.20.20.330 2 346 2.9E-126 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 Tharo_3092 c5aefccd61fafa4349463e3fdc4b6c49 1257 SUPERFAMILY SSF82282 8 406 1.2E-114 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 Tharo_3092 c5aefccd61fafa4349463e3fdc4b6c49 1257 PIRSF PIRSF000381 2 1230 0.0 T 14-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_3092 c5aefccd61fafa4349463e3fdc4b6c49 1257 Gene3D G3DSA:1.10.288.10 970 1127 3.2E-134 T 14-10-2018 Tharo_3092 c5aefccd61fafa4349463e3fdc4b6c49 1257 Gene3D G3DSA:1.10.1240.10 662 754 7.2E-37 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_3092 c5aefccd61fafa4349463e3fdc4b6c49 1257 SUPERFAMILY SSF52242 762 911 1.31E-46 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 Tharo_2779 3cbe0f9475ccd3f6eb168fd7b678d38d 494 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 20 438 4.8E-81 T 14-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 Tharo_2779 3cbe0f9475ccd3f6eb168fd7b678d38d 494 Gene3D G3DSA:3.40.1670.10 334 453 1.3E-24 T 14-10-2018 Tharo_2779 3cbe0f9475ccd3f6eb168fd7b678d38d 494 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 23 425 4.3E-111 T 14-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 Tharo_2779 3cbe0f9475ccd3f6eb168fd7b678d38d 494 SUPERFAMILY SSF50475 17 318 7.45E-80 T 14-10-2018 Tharo_2779 3cbe0f9475ccd3f6eb168fd7b678d38d 494 TIGRFAM TIGR02723 phenyl_P_alpha: phenylphosphate carboxylase, alpha subunit 10 494 0.0 T 14-10-2018 IPR014095 Phenylphosphate carboxylase, alpha subunit Tharo_2779 3cbe0f9475ccd3f6eb168fd7b678d38d 494 SUPERFAMILY SSF143968 325 490 1.44E-36 T 14-10-2018 Tharo_1743 175ee91d55981704745d8ea4a7849773 563 SUPERFAMILY SSF46626 13 142 1.95E-18 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_1743 175ee91d55981704745d8ea4a7849773 563 Pfam PF02239 Cytochrome D1 heme domain 160 558 5.9E-158 T 14-10-2018 Tharo_1743 175ee91d55981704745d8ea4a7849773 563 Gene3D G3DSA:2.140.10.20 132 563 8.2E-192 T 14-10-2018 IPR003143 Cytochrome cd1-nitrite reductase, C-terminal domain superfamily Tharo_1743 175ee91d55981704745d8ea4a7849773 563 SUPERFAMILY SSF51004 132 563 3.92E-119 T 14-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily Tharo_1743 175ee91d55981704745d8ea4a7849773 563 Gene3D G3DSA:1.10.760.10 23 131 2.2E-34 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_1743 175ee91d55981704745d8ea4a7849773 563 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 38 123 3.9E-10 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_2047 a0bdae6790d3f3bd69797f21f6c93bb8 137 Gene3D G3DSA:3.40.50.1010 1 131 1.6E-33 T 14-10-2018 Tharo_2047 a0bdae6790d3f3bd69797f21f6c93bb8 137 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 129 9.572 T 14-10-2018 IPR022907 VapC family GO:0004540 Tharo_2047 a0bdae6790d3f3bd69797f21f6c93bb8 137 SUPERFAMILY SSF88723 1 131 3.92E-29 T 14-10-2018 IPR029060 PIN-like domain superfamily Tharo_2047 a0bdae6790d3f3bd69797f21f6c93bb8 137 Pfam PF01850 PIN domain 3 122 2.1E-18 T 14-10-2018 IPR002716 PIN domain Tharo_1184 a309f1870562fc0945e33f73a8d96a56 380 SUPERFAMILY SSF55347 139 365 8.11E-73 T 14-10-2018 Tharo_1184 a309f1870562fc0945e33f73a8d96a56 380 SMART SM00859 6 127 1.3E-30 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Tharo_1184 a309f1870562fc0945e33f73a8d96a56 380 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 4 378 33.924 T 14-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Tharo_1184 a309f1870562fc0945e33f73a8d96a56 380 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 272 286 - T 14-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Tharo_1184 a309f1870562fc0945e33f73a8d96a56 380 Gene3D G3DSA:3.30.360.10 140 361 3.5E-142 T 14-10-2018 Tharo_1184 a309f1870562fc0945e33f73a8d96a56 380 Gene3D G3DSA:3.40.50.720 7 367 3.5E-142 T 14-10-2018 Tharo_1184 a309f1870562fc0945e33f73a8d96a56 380 PIRSF PIRSF000148 4 380 2.4E-61 T 14-10-2018 Tharo_1184 a309f1870562fc0945e33f73a8d96a56 380 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 126 2.5E-27 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Tharo_1184 a309f1870562fc0945e33f73a8d96a56 380 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 149 364 9.6E-51 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Tharo_1184 a309f1870562fc0945e33f73a8d96a56 380 SUPERFAMILY SSF51735 4 152 2.63E-53 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1184 a309f1870562fc0945e33f73a8d96a56 380 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 6 378 7.8E-190 T 14-10-2018 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Tharo_2400 8ba21ca523b670fc34a7e4dc741fc054 338 Pfam PF00490 Delta-aminolevulinic acid dehydratase 10 333 3.2E-137 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Tharo_2400 8ba21ca523b670fc34a7e4dc741fc054 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 127 141 3.8E-56 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Tharo_2400 8ba21ca523b670fc34a7e4dc741fc054 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 253 269 3.8E-56 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Tharo_2400 8ba21ca523b670fc34a7e4dc741fc054 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 308 327 3.8E-56 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Tharo_2400 8ba21ca523b670fc34a7e4dc741fc054 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 199 218 3.8E-56 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Tharo_2400 8ba21ca523b670fc34a7e4dc741fc054 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 278 293 3.8E-56 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Tharo_2400 8ba21ca523b670fc34a7e4dc741fc054 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 161 180 3.8E-56 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Tharo_2400 8ba21ca523b670fc34a7e4dc741fc054 338 SUPERFAMILY SSF51569 6 335 1.35E-140 T 14-10-2018 Tharo_2400 8ba21ca523b670fc34a7e4dc741fc054 338 PIRSF PIRSF001415 1 337 4.0E-146 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Tharo_2400 8ba21ca523b670fc34a7e4dc741fc054 338 Gene3D G3DSA:3.20.20.70 2 338 9.1E-142 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_2400 8ba21ca523b670fc34a7e4dc741fc054 338 SMART SM01004 7 334 8.5E-237 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Tharo_2504 e2fad2e6ad8b1b39158c4ce6d674c928 570 SUPERFAMILY SSF52518 366 567 1.22E-65 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_2504 e2fad2e6ad8b1b39158c4ce6d674c928 570 SUPERFAMILY SSF52518 2 181 1.81E-62 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_2504 e2fad2e6ad8b1b39158c4ce6d674c928 570 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 328 2.0E-41 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 Tharo_2504 e2fad2e6ad8b1b39158c4ce6d674c928 570 Gene3D G3DSA:3.40.50.970 1 185 2.4E-72 T 14-10-2018 Tharo_2504 e2fad2e6ad8b1b39158c4ce6d674c928 570 Gene3D G3DSA:3.40.50.970 362 568 2.0E-64 T 14-10-2018 Tharo_2504 e2fad2e6ad8b1b39158c4ce6d674c928 570 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 170 5.6E-58 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Tharo_2504 e2fad2e6ad8b1b39158c4ce6d674c928 570 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 3 565 3.4E-250 T 14-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 Tharo_2504 e2fad2e6ad8b1b39158c4ce6d674c928 570 Gene3D G3DSA:3.40.50.1220 187 358 5.9E-58 T 14-10-2018 Tharo_2504 e2fad2e6ad8b1b39158c4ce6d674c928 570 SUPERFAMILY SSF52467 186 360 7.32E-62 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Tharo_2504 e2fad2e6ad8b1b39158c4ce6d674c928 570 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 392 541 7.3E-47 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Tharo_1607 5680cd1bd03f49b17b21dba1f24dbbd8 533 SUPERFAMILY SSF56425 231 345 4.34E-42 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_1607 5680cd1bd03f49b17b21dba1f24dbbd8 533 SUPERFAMILY SSF46977 416 514 4.32E-29 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_1607 5680cd1bd03f49b17b21dba1f24dbbd8 533 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 4 511 1.0E-194 T 14-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 Tharo_1607 5680cd1bd03f49b17b21dba1f24dbbd8 533 Gene3D G3DSA:1.20.58.100 416 530 1.6E-41 T 14-10-2018 Tharo_1607 5680cd1bd03f49b17b21dba1f24dbbd8 533 Pfam PF00890 FAD binding domain 6 385 4.8E-101 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_1607 5680cd1bd03f49b17b21dba1f24dbbd8 533 SUPERFAMILY SSF51905 3 439 1.56E-74 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1607 5680cd1bd03f49b17b21dba1f24dbbd8 533 Pfam PF02910 Fumarate reductase flavoprotein C-term 433 512 4.5E-13 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_1607 5680cd1bd03f49b17b21dba1f24dbbd8 533 Gene3D G3DSA:3.50.50.60 6 397 1.2E-158 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1607 5680cd1bd03f49b17b21dba1f24dbbd8 533 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 348 370 6.3E-10 T 14-10-2018 Tharo_1607 5680cd1bd03f49b17b21dba1f24dbbd8 533 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 6.3E-10 T 14-10-2018 Tharo_1607 5680cd1bd03f49b17b21dba1f24dbbd8 533 Gene3D G3DSA:3.90.700.10 241 351 1.2E-158 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 Gene3D G3DSA:1.10.601.10 153 498 3.9E-132 T 14-10-2018 Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 Gene3D G3DSA:1.10.10.10 502 577 3.2E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 PRINTS PR00046 Major sigma-70 factor signature 477 485 9.2E-31 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 PRINTS PR00046 Major sigma-70 factor signature 637 648 9.2E-31 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 PRINTS PR00046 Major sigma-70 factor signature 601 613 9.2E-31 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 PRINTS PR00046 Major sigma-70 factor signature 622 637 9.2E-31 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 PRINTS PR00046 Major sigma-70 factor signature 453 466 9.2E-31 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 453 466 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 425 661 2.5E-119 T 14-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 20 662 43.522 T 14-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 SUPERFAMILY SSF88946 155 496 3.3E-99 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 Gene3D G3DSA:1.10.10.10 579 663 8.6E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 Pfam PF04545 Sigma-70, region 4 597 650 6.7E-19 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 622 648 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 Pfam PF04546 Sigma-70, non-essential region 179 398 1.6E-63 T 14-10-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 Gene3D G3DSA:1.10.220.120 40 102 9.5E-27 T 14-10-2018 Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 Pfam PF00140 Sigma-70 factor, region 1.2 138 170 1.3E-13 T 14-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 425 650 5.7E-38 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 SUPERFAMILY SSF88659 502 575 7.52E-19 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 Pfam PF04539 Sigma-70 region 3 508 583 3.4E-25 T 14-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 SUPERFAMILY SSF88659 559 661 5.01E-26 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 Pfam PF04542 Sigma-70 region 2 431 498 7.2E-21 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Tharo_2485 8f0bdcba9261d7c4556bc280e96d13e4 665 Pfam PF03979 Sigma-70 factor, region 1.1 43 120 2.7E-27 T 14-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 Tharo_2071 46b5229d14e9a1fd79f0ce5a951c459c 605 SUPERFAMILY SSF54980 398 512 7.67E-32 T 14-10-2018 IPR035647 EF-G domain III/V-like Tharo_2071 46b5229d14e9a1fd79f0ce5a951c459c 605 Pfam PF03144 Elongation factor Tu domain 2 220 289 1.2E-10 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Tharo_2071 46b5229d14e9a1fd79f0ce5a951c459c 605 SUPERFAMILY SSF52540 4 206 1.06E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2071 46b5229d14e9a1fd79f0ce5a951c459c 605 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 5 598 2.7E-292 T 14-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 Tharo_2071 46b5229d14e9a1fd79f0ce5a951c459c 605 SUPERFAMILY SSF54980 302 387 8.27E-14 T 14-10-2018 IPR035647 EF-G domain III/V-like Tharo_2071 46b5229d14e9a1fd79f0ce5a951c459c 605 Gene3D G3DSA:3.30.70.870 306 589 2.0E-130 T 14-10-2018 Tharo_2071 46b5229d14e9a1fd79f0ce5a951c459c 605 SMART SM00838 398 483 2.9E-4 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like Tharo_2071 46b5229d14e9a1fd79f0ce5a951c459c 605 Gene3D G3DSA:2.40.50.250 482 598 2.0E-130 T 14-10-2018 Tharo_2071 46b5229d14e9a1fd79f0ce5a951c459c 605 Gene3D G3DSA:3.40.50.300 2 198 2.0E-67 T 14-10-2018 Tharo_2071 46b5229d14e9a1fd79f0ce5a951c459c 605 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site Tharo_2071 46b5229d14e9a1fd79f0ce5a951c459c 605 Gene3D G3DSA:2.40.30.10 199 298 3.8E-30 T 14-10-2018 Tharo_2071 46b5229d14e9a1fd79f0ce5a951c459c 605 Pfam PF00679 Elongation factor G C-terminus 397 482 2.4E-24 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like Tharo_2071 46b5229d14e9a1fd79f0ce5a951c459c 605 SUPERFAMILY SSF50447 151 299 1.18E-30 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Tharo_2071 46b5229d14e9a1fd79f0ce5a951c459c 605 PRINTS PR00315 GTP-binding elongation factor signature 123 132 2.5E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2071 46b5229d14e9a1fd79f0ce5a951c459c 605 PRINTS PR00315 GTP-binding elongation factor signature 87 98 2.5E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2071 46b5229d14e9a1fd79f0ce5a951c459c 605 PRINTS PR00315 GTP-binding elongation factor signature 51 59 2.5E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2071 46b5229d14e9a1fd79f0ce5a951c459c 605 PRINTS PR00315 GTP-binding elongation factor signature 71 81 2.5E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2071 46b5229d14e9a1fd79f0ce5a951c459c 605 PRINTS PR00315 GTP-binding elongation factor signature 7 20 2.5E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2071 46b5229d14e9a1fd79f0ce5a951c459c 605 Gene3D G3DSA:3.30.70.240 389 481 2.0E-130 T 14-10-2018 Tharo_2071 46b5229d14e9a1fd79f0ce5a951c459c 605 Pfam PF00009 Elongation factor Tu GTP binding domain 4 195 1.7E-55 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2071 46b5229d14e9a1fd79f0ce5a951c459c 605 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 152 9.7E-24 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Tharo_0471 2e99f6285842dc6cde644febbeba87c2 389 SUPERFAMILY SSF53335 147 369 1.41E-44 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_0471 2e99f6285842dc6cde644febbeba87c2 389 Pfam PF02926 THUMP domain 19 155 1.2E-11 T 14-10-2018 IPR004114 THUMP domain GO:0003723 Tharo_0471 2e99f6285842dc6cde644febbeba87c2 389 Gene3D G3DSA:3.40.50.150 170 366 3.3E-129 T 14-10-2018 Tharo_0471 2e99f6285842dc6cde644febbeba87c2 389 SMART SM00981 57 155 1.2E-18 T 14-10-2018 IPR004114 THUMP domain GO:0003723 Tharo_0471 2e99f6285842dc6cde644febbeba87c2 389 Pfam PF01170 Putative RNA methylase family UPF0020 163 368 3.0E-50 T 14-10-2018 IPR000241 Putative RNA methylase domain Tharo_0471 2e99f6285842dc6cde644febbeba87c2 389 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 196 207 - T 14-10-2018 IPR000241 Putative RNA methylase domain Tharo_0471 2e99f6285842dc6cde644febbeba87c2 389 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 297 309 3.2E-5 T 14-10-2018 Tharo_0471 2e99f6285842dc6cde644febbeba87c2 389 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 194 208 3.2E-5 T 14-10-2018 Tharo_0471 2e99f6285842dc6cde644febbeba87c2 389 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 300 306 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Tharo_0471 2e99f6285842dc6cde644febbeba87c2 389 Gene3D G3DSA:3.30.2130.30 6 252 3.3E-129 T 14-10-2018 Tharo_2271 0debad46739a1a199f571142f61a5604 723 SUPERFAMILY SSF55874 393 574 8.51E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2271 0debad46739a1a199f571142f61a5604 723 Gene3D G3DSA:1.10.287.560 330 390 8.6E-8 T 14-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 Tharo_2271 0debad46739a1a199f571142f61a5604 723 Pfam PF01584 CheW-like domain 583 703 8.3E-22 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Tharo_2271 0debad46739a1a199f571142f61a5604 723 SUPERFAMILY SSF160246 264 323 7.59E-6 T 14-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily Tharo_2271 0debad46739a1a199f571142f61a5604 723 SUPERFAMILY SSF47384 331 391 7.85E-10 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_2271 0debad46739a1a199f571142f61a5604 723 Gene3D G3DSA:2.30.30.40 576 697 2.7E-30 T 14-10-2018 Tharo_2271 0debad46739a1a199f571142f61a5604 723 Pfam PF01627 Hpt domain 7 92 1.4E-18 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Tharo_2271 0debad46739a1a199f571142f61a5604 723 SMART SM00387 435 576 1.0E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2271 0debad46739a1a199f571142f61a5604 723 SMART SM00073 2 100 3.7E-22 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Tharo_2271 0debad46739a1a199f571142f61a5604 723 SUPERFAMILY SSF50341 575 701 4.05E-27 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 Tharo_2271 0debad46739a1a199f571142f61a5604 723 Gene3D G3DSA:1.20.120.160 1 138 3.6E-35 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 Tharo_2271 0debad46739a1a199f571142f61a5604 723 SMART SM00260 568 701 7.3E-25 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Tharo_2271 0debad46739a1a199f571142f61a5604 723 SMART SM01231 330 390 4.4E-13 T 14-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 Tharo_2271 0debad46739a1a199f571142f61a5604 723 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 438 575 1.0E-15 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2271 0debad46739a1a199f571142f61a5604 723 Gene3D G3DSA:3.30.565.10 391 575 1.6E-55 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2271 0debad46739a1a199f571142f61a5604 723 SUPERFAMILY SSF47226 6 126 2.12E-30 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 Tharo_2271 0debad46739a1a199f571142f61a5604 723 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 331 389 1.2E-6 T 14-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 Tharo_2271 0debad46739a1a199f571142f61a5604 723 Gene3D G3DSA:2.40.50.180 599 656 2.7E-30 T 14-10-2018 Tharo_2271 0debad46739a1a199f571142f61a5604 723 PRINTS PR00344 Bacterial sensor protein C-terminal signature 520 530 1.1E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2271 0debad46739a1a199f571142f61a5604 723 PRINTS PR00344 Bacterial sensor protein C-terminal signature 560 573 1.1E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2271 0debad46739a1a199f571142f61a5604 723 PRINTS PR00344 Bacterial sensor protein C-terminal signature 536 554 1.1E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2271 0debad46739a1a199f571142f61a5604 723 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 494 1.1E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1909 89e1d7f4c3afbe79a0d29594cd106cc5 161 SUPERFAMILY SSF52788 1 135 6.02E-37 T 14-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily Tharo_1909 89e1d7f4c3afbe79a0d29594cd106cc5 161 SMART SM00226 1 135 9.9E-38 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I Tharo_1909 89e1d7f4c3afbe79a0d29594cd106cc5 161 Gene3D G3DSA:3.40.50.2300 1 135 6.8E-37 T 14-10-2018 Tharo_1909 89e1d7f4c3afbe79a0d29594cd106cc5 161 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 133 6.3E-20 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I Tharo_2796 a1923dfd9088c209524c1d7ba4a42cb7 216 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 25 39 2.9E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_2796 a1923dfd9088c209524c1d7ba4a42cb7 216 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 55 2.9E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_2796 a1923dfd9088c209524c1d7ba4a42cb7 216 SUPERFAMILY SSF46785 2 69 4.97E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_2796 a1923dfd9088c209524c1d7ba4a42cb7 216 Pfam PF07729 FCD domain 75 198 3.7E-29 T 14-10-2018 IPR011711 GntR, C-terminal Tharo_2796 a1923dfd9088c209524c1d7ba4a42cb7 216 SUPERFAMILY SSF48008 72 205 1.23E-30 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Tharo_2796 a1923dfd9088c209524c1d7ba4a42cb7 216 Gene3D G3DSA:1.10.10.10 1 67 2.4E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2796 a1923dfd9088c209524c1d7ba4a42cb7 216 SMART SM00345 7 65 3.9E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_2796 a1923dfd9088c209524c1d7ba4a42cb7 216 SMART SM00895 75 199 6.2E-25 T 14-10-2018 IPR011711 GntR, C-terminal Tharo_2796 a1923dfd9088c209524c1d7ba4a42cb7 216 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 65 2.4E-21 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_2796 a1923dfd9088c209524c1d7ba4a42cb7 216 Gene3D G3DSA:1.20.120.530 68 207 1.5E-32 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Tharo_2404 185dafdaa0ef2be352930a23411d963e 223 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 6 213 1.6E-66 T 14-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 Tharo_2404 185dafdaa0ef2be352930a23411d963e 223 Gene3D G3DSA:3.40.50.1360 7 207 2.3E-75 T 14-10-2018 Tharo_2404 185dafdaa0ef2be352930a23411d963e 223 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 49 211 9.8E-57 T 14-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 Tharo_2404 185dafdaa0ef2be352930a23411d963e 223 Gene3D G3DSA:3.30.70.260 125 196 2.3E-75 T 14-10-2018 Tharo_2404 185dafdaa0ef2be352930a23411d963e 223 SUPERFAMILY SSF100950 1 147 5.58E-45 T 14-10-2018 IPR037171 NagB/RpiA transferase-like Tharo_2404 185dafdaa0ef2be352930a23411d963e 223 SUPERFAMILY SSF75445 127 198 7.06E-24 T 14-10-2018 Tharo_2404 185dafdaa0ef2be352930a23411d963e 223 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 217 32.659 T 14-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 Tharo_1313 e5a46402bbc33852c218de775af1eb98 382 SUPERFAMILY SSF53822 24 380 1.18E-76 T 14-10-2018 IPR028082 Periplasmic binding protein-like I Tharo_1313 e5a46402bbc33852c218de775af1eb98 382 Gene3D G3DSA:3.40.50.2300 141 373 2.5E-121 T 14-10-2018 Tharo_1313 e5a46402bbc33852c218de775af1eb98 382 Pfam PF13458 Periplasmic binding protein 23 376 2.6E-52 T 14-10-2018 IPR028081 Leucine-binding protein domain Tharo_1313 e5a46402bbc33852c218de775af1eb98 382 Gene3D G3DSA:3.40.50.2300 26 364 2.5E-121 T 14-10-2018 Tharo_3207 2f1c1806639555f21562d7c99bcf98e9 212 Gene3D G3DSA:1.10.1760.20 1 200 8.6E-13 T 14-10-2018 Tharo_3207 2f1c1806639555f21562d7c99bcf98e9 212 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 197 1.4E-30 T 14-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 Tharo_0018 c76f80a64895540c97aa5b043a7a0985 685 Gene3D G3DSA:2.40.170.20 163 685 2.8E-63 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Tharo_0018 c76f80a64895540c97aa5b043a7a0985 685 Pfam PF00593 TonB dependent receptor 350 684 8.4E-43 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Tharo_0018 c76f80a64895540c97aa5b043a7a0985 685 Gene3D G3DSA:2.170.130.10 43 159 1.6E-25 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Tharo_0018 c76f80a64895540c97aa5b043a7a0985 685 SUPERFAMILY SSF56935 34 685 2.33E-91 T 14-10-2018 Tharo_0018 c76f80a64895540c97aa5b043a7a0985 685 Pfam PF07715 TonB-dependent Receptor Plug Domain 48 150 9.9E-16 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain Tharo_0792 480b9e9046184e13b1d6abe54db28702 618 SMART SM00382 383 575 1.8E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0792 480b9e9046184e13b1d6abe54db28702 618 Gene3D G3DSA:1.20.1560.10 29 347 3.3E-114 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Tharo_0792 480b9e9046184e13b1d6abe54db28702 618 Pfam PF00664 ABC transporter transmembrane region 37 309 8.8E-39 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Tharo_0792 480b9e9046184e13b1d6abe54db28702 618 SUPERFAMILY SSF52540 348 593 2.57E-91 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0792 480b9e9046184e13b1d6abe54db28702 618 ProSitePatterns PS00211 ABC transporters family signature. 495 509 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_0792 480b9e9046184e13b1d6abe54db28702 618 SUPERFAMILY SSF90123 24 341 6.41E-62 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Tharo_0792 480b9e9046184e13b1d6abe54db28702 618 Pfam PF00005 ABC transporter 376 523 3.7E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_0792 480b9e9046184e13b1d6abe54db28702 618 Gene3D G3DSA:3.40.50.300 355 609 7.4E-95 T 14-10-2018 Tharo_0503 b09a4507c7537934335ca84545b89146 149 Gene3D G3DSA:3.10.430.100 61 148 8.3E-27 T 14-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily Tharo_0503 b09a4507c7537934335ca84545b89146 149 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 14-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_0503 b09a4507c7537934335ca84545b89146 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 6.9E-23 T 14-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_0503 b09a4507c7537934335ca84545b89146 149 SUPERFAMILY SSF55658 1 56 1.15E-18 T 14-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal Tharo_0503 b09a4507c7537934335ca84545b89146 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 146 2.4E-26 T 14-10-2018 IPR020069 Ribosomal protein L9, C-terminal Tharo_0503 b09a4507c7537934335ca84545b89146 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 2.5E-46 T 14-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_0503 b09a4507c7537934335ca84545b89146 149 SUPERFAMILY SSF55653 59 148 3.53E-26 T 14-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily Tharo_0503 b09a4507c7537934335ca84545b89146 149 Gene3D G3DSA:3.40.5.10 1 50 8.0E-24 T 14-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_0503 b09a4507c7537934335ca84545b89146 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 26.556 T 14-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2054 ae6af48b91bdd810bf3c9d246eae2a8f 383 SUPERFAMILY SSF53756 4 376 1.22E-31 T 14-10-2018 Tharo_2054 ae6af48b91bdd810bf3c9d246eae2a8f 383 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 4 375 2.7E-105 T 14-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 Tharo_2054 ae6af48b91bdd810bf3c9d246eae2a8f 383 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 2 379 37.269 T 14-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 Tharo_2054 ae6af48b91bdd810bf3c9d246eae2a8f 383 Pfam PF02684 Lipid-A-disaccharide synthetase 5 364 8.4E-96 T 14-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 Tharo_2054 ae6af48b91bdd810bf3c9d246eae2a8f 383 Gene3D G3DSA:3.40.50.2000 173 358 2.2E-8 T 14-10-2018 Tharo_2736 2381ebcb028ad69a638dc8b255757b2e 177 SUPERFAMILY SSF50104 121 176 1.65E-18 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily Tharo_2736 2381ebcb028ad69a638dc8b255757b2e 177 Pfam PF02357 Transcription termination factor nusG 3 108 3.8E-29 T 14-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Tharo_2736 2381ebcb028ad69a638dc8b255757b2e 177 Gene3D G3DSA:2.30.30.30 118 176 7.1E-24 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 Tharo_2736 2381ebcb028ad69a638dc8b255757b2e 177 SMART SM00739 123 150 0.0014 T 14-10-2018 IPR005824 KOW Tharo_2736 2381ebcb028ad69a638dc8b255757b2e 177 SUPERFAMILY SSF82679 3 113 1.96E-40 T 14-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Tharo_2736 2381ebcb028ad69a638dc8b255757b2e 177 Gene3D G3DSA:3.30.70.940 1 117 3.3E-48 T 14-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Tharo_2736 2381ebcb028ad69a638dc8b255757b2e 177 SMART SM00738 2 111 1.9E-51 T 14-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Tharo_2736 2381ebcb028ad69a638dc8b255757b2e 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 25.404 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 Tharo_2736 2381ebcb028ad69a638dc8b255757b2e 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 5.1E-19 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 Tharo_2736 2381ebcb028ad69a638dc8b255757b2e 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 5.1E-19 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 Tharo_2736 2381ebcb028ad69a638dc8b255757b2e 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 5.1E-19 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 Tharo_2736 2381ebcb028ad69a638dc8b255757b2e 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 14-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site Tharo_2736 2381ebcb028ad69a638dc8b255757b2e 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 1.8E-69 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 Tharo_0103 383057f85429c80ff42c0adc9a9ec5d0 404 Pfam PF07690 Major Facilitator Superfamily 23 358 2.2E-25 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_0103 383057f85429c80ff42c0adc9a9ec5d0 404 SUPERFAMILY SSF103473 10 393 1.15E-48 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_0103 383057f85429c80ff42c0adc9a9ec5d0 404 Gene3D G3DSA:1.20.1250.20 9 394 2.7E-38 T 14-10-2018 Tharo_2429 1ef9b76faf0baccbfdd9fc6533e25e7d 342 PIRSF PIRSF000149 1 342 6.1E-133 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2429 1ef9b76faf0baccbfdd9fc6533e25e7d 342 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 333 2.0E-128 T 14-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2429 1ef9b76faf0baccbfdd9fc6533e25e7d 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 113 126 2.3E-37 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2429 1ef9b76faf0baccbfdd9fc6533e25e7d 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 233 250 2.3E-37 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2429 1ef9b76faf0baccbfdd9fc6533e25e7d 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 150 168 2.3E-37 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2429 1ef9b76faf0baccbfdd9fc6533e25e7d 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 177 193 2.3E-37 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2429 1ef9b76faf0baccbfdd9fc6533e25e7d 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 273 288 2.3E-37 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2429 1ef9b76faf0baccbfdd9fc6533e25e7d 342 SMART SM00846 3 156 5.3E-83 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2429 1ef9b76faf0baccbfdd9fc6533e25e7d 342 Gene3D G3DSA:3.40.50.720 4 333 5.9E-142 T 14-10-2018 Tharo_2429 1ef9b76faf0baccbfdd9fc6533e25e7d 342 SUPERFAMILY SSF55347 156 322 7.79E-69 T 14-10-2018 Tharo_2429 1ef9b76faf0baccbfdd9fc6533e25e7d 342 Gene3D G3DSA:3.30.360.10 155 323 5.9E-142 T 14-10-2018 Tharo_2429 1ef9b76faf0baccbfdd9fc6533e25e7d 342 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 154 161 - T 14-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2429 1ef9b76faf0baccbfdd9fc6533e25e7d 342 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 107 1.2E-34 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2429 1ef9b76faf0baccbfdd9fc6533e25e7d 342 SUPERFAMILY SSF51735 1 155 8.86E-56 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_2429 1ef9b76faf0baccbfdd9fc6533e25e7d 342 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 161 321 1.1E-62 T 14-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1973 e0f26ec9b3ba93901cdc9f2506286887 447 SUPERFAMILY SSF55874 278 434 6.16E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1973 e0f26ec9b3ba93901cdc9f2506286887 447 SUPERFAMILY SSF158472 177 224 2.09E-5 T 14-10-2018 Tharo_1973 e0f26ec9b3ba93901cdc9f2506286887 447 Gene3D G3DSA:3.30.565.10 290 441 1.4E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1973 e0f26ec9b3ba93901cdc9f2506286887 447 SMART SM00387 326 437 4.5E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1973 e0f26ec9b3ba93901cdc9f2506286887 447 Gene3D G3DSA:1.10.287.130 173 283 1.1E-18 T 14-10-2018 Tharo_1973 e0f26ec9b3ba93901cdc9f2506286887 447 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 434 8.8E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1973 e0f26ec9b3ba93901cdc9f2506286887 447 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 377 8.8E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1973 e0f26ec9b3ba93901cdc9f2506286887 447 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 415 8.8E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1973 e0f26ec9b3ba93901cdc9f2506286887 447 SUPERFAMILY SSF47384 212 287 1.55E-10 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_1973 e0f26ec9b3ba93901cdc9f2506286887 447 Gene3D G3DSA:3.30.450.300 23 152 3.1E-41 T 14-10-2018 IPR038421 Sensor histidine kinase RisS, periplasmic domain superfamily Tharo_1973 e0f26ec9b3ba93901cdc9f2506286887 447 Pfam PF16524 Periplasmic domain of Sensor histidine kinase RisS 38 148 1.8E-35 T 14-10-2018 IPR032408 Sensor histidine kinase RisS, periplasmic domain Tharo_1973 e0f26ec9b3ba93901cdc9f2506286887 447 SMART SM00304 176 228 1.3E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_1973 e0f26ec9b3ba93901cdc9f2506286887 447 Pfam PF00672 HAMP domain 177 223 7.5E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_1973 e0f26ec9b3ba93901cdc9f2506286887 447 SMART SM00388 229 288 2.3E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1973 e0f26ec9b3ba93901cdc9f2506286887 447 Pfam PF00512 His Kinase A (phospho-acceptor) domain 233 286 1.4E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1973 e0f26ec9b3ba93901cdc9f2506286887 447 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 330 435 6.2E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_3205 71b99a3abd368a658998b78786a92303 387 Pfam PF02772 S-adenosylmethionine synthetase, central domain 116 233 4.2E-47 T 14-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Tharo_3205 71b99a3abd368a658998b78786a92303 387 Gene3D G3DSA:3.30.300.10 102 377 3.2E-180 T 14-10-2018 Tharo_3205 71b99a3abd368a658998b78786a92303 387 SUPERFAMILY SSF55973 235 383 1.61E-68 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Tharo_3205 71b99a3abd368a658998b78786a92303 387 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 101 7.6E-41 T 14-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Tharo_3205 71b99a3abd368a658998b78786a92303 387 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 235 374 1.4E-68 T 14-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Tharo_3205 71b99a3abd368a658998b78786a92303 387 Gene3D G3DSA:3.30.300.10 5 235 3.2E-180 T 14-10-2018 Tharo_3205 71b99a3abd368a658998b78786a92303 387 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 261 269 - T 14-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Tharo_3205 71b99a3abd368a658998b78786a92303 387 SUPERFAMILY SSF55973 3 110 4.71E-45 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Tharo_3205 71b99a3abd368a658998b78786a92303 387 PIRSF PIRSF000497 1 386 5.2E-174 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Tharo_3205 71b99a3abd368a658998b78786a92303 387 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 382 8.0E-184 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Tharo_3205 71b99a3abd368a658998b78786a92303 387 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 385 57.416 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Tharo_3205 71b99a3abd368a658998b78786a92303 387 SUPERFAMILY SSF55973 116 234 1.49E-52 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Tharo_3205 71b99a3abd368a658998b78786a92303 387 Gene3D G3DSA:3.30.300.10 11 272 3.2E-180 T 14-10-2018 Tharo_3205 71b99a3abd368a658998b78786a92303 387 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 118 128 - T 14-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Tharo_3013 73e452057e5303840c7193dd32c55303 1179 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 505 623 5.8E-22 T 14-10-2018 IPR000014 PAS domain Tharo_3013 73e452057e5303840c7193dd32c55303 1179 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 372 501 2.7E-15 T 14-10-2018 IPR000014 PAS domain Tharo_3013 73e452057e5303840c7193dd32c55303 1179 SUPERFAMILY SSF55785 510 613 2.27E-30 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_3013 73e452057e5303840c7193dd32c55303 1179 SMART SM00052 795 1045 5.3E-94 T 14-10-2018 IPR001633 EAL domain Tharo_3013 73e452057e5303840c7193dd32c55303 1179 Pfam PF13426 PAS domain 513 614 9.5E-19 T 14-10-2018 IPR000014 PAS domain Tharo_3013 73e452057e5303840c7193dd32c55303 1179 Pfam PF00563 EAL domain 806 1040 7.8E-67 T 14-10-2018 IPR001633 EAL domain Tharo_3013 73e452057e5303840c7193dd32c55303 1179 SMART SM00267 616 789 1.8E-66 T 14-10-2018 IPR000160 GGDEF domain Tharo_3013 73e452057e5303840c7193dd32c55303 1179 SUPERFAMILY SSF55785 365 492 7.5E-16 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_3013 73e452057e5303840c7193dd32c55303 1179 SMART SM00091 502 568 8.9E-8 T 14-10-2018 IPR000014 PAS domain Tharo_3013 73e452057e5303840c7193dd32c55303 1179 SMART SM00091 376 437 0.0013 T 14-10-2018 IPR000014 PAS domain Tharo_3013 73e452057e5303840c7193dd32c55303 1179 Pfam PF13682 Chemoreceptor zinc-binding domain 1079 1140 1.7E-10 T 14-10-2018 IPR025991 Chemoreceptor zinc-binding domain Tharo_3013 73e452057e5303840c7193dd32c55303 1179 Pfam PF02743 Cache domain 45 229 9.2E-15 T 14-10-2018 IPR033479 Double Cache domain 1 Tharo_3013 73e452057e5303840c7193dd32c55303 1179 Gene3D G3DSA:3.30.70.270 624 803 1.8E-59 T 14-10-2018 Tharo_3013 73e452057e5303840c7193dd32c55303 1179 Gene3D G3DSA:3.30.450.20 33 192 2.0E-11 T 14-10-2018 Tharo_3013 73e452057e5303840c7193dd32c55303 1179 Gene3D G3DSA:3.30.450.20 499 623 3.1E-37 T 14-10-2018 Tharo_3013 73e452057e5303840c7193dd32c55303 1179 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 623 788 7.0E-44 T 14-10-2018 IPR000160 GGDEF domain Tharo_3013 73e452057e5303840c7193dd32c55303 1179 Gene3D G3DSA:3.20.20.450 804 1050 1.6E-86 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_3013 73e452057e5303840c7193dd32c55303 1179 SUPERFAMILY SSF55073 632 790 2.35E-48 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_3013 73e452057e5303840c7193dd32c55303 1179 Pfam PF00990 Diguanylate cyclase, GGDEF domain 627 785 2.8E-49 T 14-10-2018 IPR000160 GGDEF domain Tharo_3013 73e452057e5303840c7193dd32c55303 1179 SUPERFAMILY SSF141868 805 1057 5.49E-80 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_3013 73e452057e5303840c7193dd32c55303 1179 Gene3D G3DSA:3.30.450.20 361 492 1.4E-18 T 14-10-2018 Tharo_3013 73e452057e5303840c7193dd32c55303 1179 Pfam PF13188 PAS domain 376 435 1.2E-10 T 14-10-2018 IPR000014 PAS domain Tharo_3013 73e452057e5303840c7193dd32c55303 1179 SMART SM00086 453 494 460.0 T 14-10-2018 IPR001610 PAC motif Tharo_3013 73e452057e5303840c7193dd32c55303 1179 SMART SM00086 574 616 3.4E-5 T 14-10-2018 IPR001610 PAC motif Tharo_0834 70deaf80637866e0259ba839e8f80ced 145 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 145 72.782 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Tharo_0834 70deaf80637866e0259ba839e8f80ced 145 PIRSF PIRSF001399 1 145 1.3E-60 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Tharo_0834 70deaf80637866e0259ba839e8f80ced 145 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 3 141 2.5E-60 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Tharo_0834 70deaf80637866e0259ba839e8f80ced 145 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 14-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Tharo_0834 70deaf80637866e0259ba839e8f80ced 145 Pfam PF01220 Dehydroquinase class II 3 140 1.6E-62 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Tharo_0834 70deaf80637866e0259ba839e8f80ced 145 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 4 143 5.0E-49 T 14-10-2018 Tharo_0834 70deaf80637866e0259ba839e8f80ced 145 SUPERFAMILY SSF52304 3 143 3.66E-62 T 14-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Tharo_0834 70deaf80637866e0259ba839e8f80ced 145 Gene3D G3DSA:3.40.50.9100 1 144 2.9E-67 T 14-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Tharo_1707 ecb18d077d7cd0964c708344c143edff 788 PIRSF PIRSF000854 1 788 0.0 T 14-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 Tharo_1707 ecb18d077d7cd0964c708344c143edff 788 SUPERFAMILY SSF52009 345 464 9.55E-35 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 Tharo_1707 ecb18d077d7cd0964c708344c143edff 788 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 478 781 2.1E-62 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 Tharo_1707 ecb18d077d7cd0964c708344c143edff 788 SUPERFAMILY SSF51621 458 786 2.62E-97 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Tharo_1707 ecb18d077d7cd0964c708344c143edff 788 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 17 339 4.0E-119 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 Tharo_1707 ecb18d077d7cd0964c708344c143edff 788 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 5 785 0.0 T 14-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 Tharo_1707 ecb18d077d7cd0964c708344c143edff 788 Pfam PF00391 PEP-utilising enzyme, mobile domain 381 452 2.8E-26 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 Tharo_1707 ecb18d077d7cd0964c708344c143edff 788 Gene3D G3DSA:3.50.30.10 367 474 3.2E-41 T 14-10-2018 Tharo_1707 ecb18d077d7cd0964c708344c143edff 788 Gene3D G3DSA:3.30.1490.20 1 190 1.8E-71 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Tharo_1707 ecb18d077d7cd0964c708344c143edff 788 Gene3D G3DSA:3.20.20.60 475 786 1.4E-101 T 14-10-2018 Tharo_1707 ecb18d077d7cd0964c708344c143edff 788 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 691 709 - T 14-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 Tharo_1707 ecb18d077d7cd0964c708344c143edff 788 Gene3D G3DSA:3.30.470.20 191 354 6.5E-60 T 14-10-2018 Tharo_1707 ecb18d077d7cd0964c708344c143edff 788 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 411 422 - T 14-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 Tharo_1707 ecb18d077d7cd0964c708344c143edff 788 SUPERFAMILY SSF56059 1 381 2.24E-110 T 14-10-2018 Tharo_2397 e87ef517a02bebd6f11566c07f3287f5 330 SMART SM00876 237 329 1.8E-45 T 14-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 Tharo_2397 e87ef517a02bebd6f11566c07f3287f5 330 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 237 327 2.2E-20 T 14-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 Tharo_2397 e87ef517a02bebd6f11566c07f3287f5 330 Pfam PF04055 Radical SAM superfamily 67 215 3.2E-14 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_2397 e87ef517a02bebd6f11566c07f3287f5 330 SUPERFAMILY SSF102114 22 328 3.4E-90 T 14-10-2018 Tharo_2397 e87ef517a02bebd6f11566c07f3287f5 330 Gene3D G3DSA:3.20.20.70 21 330 1.5E-125 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_2397 e87ef517a02bebd6f11566c07f3287f5 330 PIRSF PIRSF001619 9 330 1.4E-129 T 14-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 Tharo_2397 e87ef517a02bebd6f11566c07f3287f5 330 Hamap MF_01694 Biotin synthase [bioB]. 22 330 41.761 T 14-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 Tharo_2397 e87ef517a02bebd6f11566c07f3287f5 330 SMART SM00729 60 272 3.1E-36 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Tharo_2397 e87ef517a02bebd6f11566c07f3287f5 330 TIGRFAM TIGR00433 bioB: biotin synthase 31 327 1.8E-120 T 14-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 Tharo_3116 a325031602e7049c788c9f6283a61282 462 Gene3D G3DSA:3.40.50.2300 1 134 2.2E-27 T 14-10-2018 Tharo_3116 a325031602e7049c788c9f6283a61282 462 Gene3D G3DSA:1.10.10.60 410 460 6.1E-12 T 14-10-2018 Tharo_3116 a325031602e7049c788c9f6283a61282 462 Pfam PF00072 Response regulator receiver domain 5 112 8.1E-19 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_3116 a325031602e7049c788c9f6283a61282 462 Pfam PF02954 Bacterial regulatory protein, Fis family 417 456 1.3E-11 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_3116 a325031602e7049c788c9f6283a61282 462 SUPERFAMILY SSF52540 143 384 2.22E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3116 a325031602e7049c788c9f6283a61282 462 SUPERFAMILY SSF52172 2 187 1.1E-34 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_3116 a325031602e7049c788c9f6283a61282 462 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 439 459 1.4E-6 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_3116 a325031602e7049c788c9f6283a61282 462 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 422 439 1.4E-6 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_3116 a325031602e7049c788c9f6283a61282 462 SMART SM00448 3 113 2.3E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_3116 a325031602e7049c788c9f6283a61282 462 SUPERFAMILY SSF46689 356 458 3.41E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_3116 a325031602e7049c788c9f6283a61282 462 Gene3D G3DSA:3.40.50.300 135 313 5.5E-61 T 14-10-2018 Tharo_3116 a325031602e7049c788c9f6283a61282 462 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 229 244 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Tharo_3116 a325031602e7049c788c9f6283a61282 462 SMART SM00382 163 306 4.2E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_3116 a325031602e7049c788c9f6283a61282 462 Gene3D G3DSA:1.10.8.60 314 380 6.3E-21 T 14-10-2018 Tharo_3116 a325031602e7049c788c9f6283a61282 462 Pfam PF00158 Sigma-54 interaction domain 143 309 6.6E-64 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Tharo_3128 b2cac0633b233d5742e70d8d6e89e9e5 313 SUPERFAMILY SSF53335 10 238 2.13E-30 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_3128 b2cac0633b233d5742e70d8d6e89e9e5 313 Gene3D G3DSA:3.40.50.150 7 291 5.0E-65 T 14-10-2018 Tharo_3128 b2cac0633b233d5742e70d8d6e89e9e5 313 Pfam PF13649 Methyltransferase domain 107 192 7.3E-10 T 14-10-2018 Tharo_3128 b2cac0633b233d5742e70d8d6e89e9e5 313 PIRSF PIRSF018249 2 290 1.2E-73 T 14-10-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 Tharo_1388 cfe43f162a05f833d1c8c7cdb53cf760 386 Pfam PF00072 Response regulator receiver domain 270 381 5.0E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1388 cfe43f162a05f833d1c8c7cdb53cf760 386 Gene3D G3DSA:3.40.50.2300 255 386 3.6E-35 T 14-10-2018 Tharo_1388 cfe43f162a05f833d1c8c7cdb53cf760 386 SUPERFAMILY SSF52172 268 385 1.42E-34 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1388 cfe43f162a05f833d1c8c7cdb53cf760 386 SMART SM00448 268 381 5.0E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2913 b72308b89afd0eed80d57e1cb5ab0686 150 SUPERFAMILY SSF52402 1 145 2.09E-35 T 14-10-2018 Tharo_2913 b72308b89afd0eed80d57e1cb5ab0686 150 Pfam PF00582 Universal stress protein family 1 145 1.1E-29 T 14-10-2018 IPR006016 UspA Tharo_2913 b72308b89afd0eed80d57e1cb5ab0686 150 PRINTS PR01438 Universal stress protein signature 123 145 2.1E-15 T 14-10-2018 IPR006015 Universal stress protein A Tharo_2913 b72308b89afd0eed80d57e1cb5ab0686 150 PRINTS PR01438 Universal stress protein signature 105 117 2.1E-15 T 14-10-2018 IPR006015 Universal stress protein A Tharo_2913 b72308b89afd0eed80d57e1cb5ab0686 150 PRINTS PR01438 Universal stress protein signature 2 20 2.1E-15 T 14-10-2018 IPR006015 Universal stress protein A Tharo_2913 b72308b89afd0eed80d57e1cb5ab0686 150 Gene3D G3DSA:3.40.50.620 1 146 1.5E-35 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_2587 711dddb1dfbf62b37e03a382d9ef51a6 259 SMART SM00331 21 245 8.8E-21 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Tharo_2587 711dddb1dfbf62b37e03a382d9ef51a6 259 Pfam PF13672 Protein phosphatase 2C 12 205 4.6E-8 T 14-10-2018 Tharo_2587 711dddb1dfbf62b37e03a382d9ef51a6 259 SMART SM00332 1 243 1.7E-11 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Tharo_2587 711dddb1dfbf62b37e03a382d9ef51a6 259 Gene3D G3DSA:3.60.40.10 2 246 3.4E-47 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Tharo_2587 711dddb1dfbf62b37e03a382d9ef51a6 259 SUPERFAMILY SSF81606 6 245 6.41E-47 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Tharo_3441 de24f5ec62a38c5540e28cd17203ce06 260 SMART SM00382 97 230 6.7E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_3441 de24f5ec62a38c5540e28cd17203ce06 260 Pfam PF01695 IstB-like ATP binding protein 54 229 1.6E-58 T 14-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 Tharo_3441 de24f5ec62a38c5540e28cd17203ce06 260 SUPERFAMILY SSF52540 85 230 4.37E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3441 de24f5ec62a38c5540e28cd17203ce06 260 PIRSF PIRSF003073 1 252 9.7E-72 T 14-10-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein Tharo_3441 de24f5ec62a38c5540e28cd17203ce06 260 Gene3D G3DSA:3.40.50.300 64 249 3.8E-43 T 14-10-2018 Tharo_1245 c8d5523f8cad8775702e7ffccadab600 304 Gene3D G3DSA:3.40.190.10 85 282 9.4E-55 T 14-10-2018 Tharo_1245 c8d5523f8cad8775702e7ffccadab600 304 Pfam PF03466 LysR substrate binding domain 91 285 7.0E-25 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_1245 c8d5523f8cad8775702e7ffccadab600 304 Gene3D G3DSA:1.10.10.10 1 84 1.1E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1245 c8d5523f8cad8775702e7ffccadab600 304 SUPERFAMILY SSF46785 1 82 4.08E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1245 c8d5523f8cad8775702e7ffccadab600 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.4E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1245 c8d5523f8cad8775702e7ffccadab600 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.4E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1245 c8d5523f8cad8775702e7ffccadab600 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.4E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1245 c8d5523f8cad8775702e7ffccadab600 304 Gene3D G3DSA:3.40.190.10 165 258 9.4E-55 T 14-10-2018 Tharo_1245 c8d5523f8cad8775702e7ffccadab600 304 SUPERFAMILY SSF53850 85 286 4.48E-39 T 14-10-2018 Tharo_1245 c8d5523f8cad8775702e7ffccadab600 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 7.3E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1219 4a96d2c513397c73d2cd1e4389d9f0c2 263 Pfam PF10108 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB 47 260 2.5E-91 T 14-10-2018 IPR019288 Predicted 3'-5' exonuclease, PolB-like Tharo_1219 4a96d2c513397c73d2cd1e4389d9f0c2 263 SUPERFAMILY SSF53098 2 226 1.27E-39 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_1219 4a96d2c513397c73d2cd1e4389d9f0c2 263 Gene3D G3DSA:3.30.420.10 4 218 2.1E-18 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_1425 48880dda150f64f9dce5ca2b193fe281 337 Pfam PF00892 EamA-like transporter family 13 143 1.3E-8 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Tharo_1425 48880dda150f64f9dce5ca2b193fe281 337 Pfam PF00892 EamA-like transporter family 157 289 1.4E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Tharo_1425 48880dda150f64f9dce5ca2b193fe281 337 SUPERFAMILY SSF103481 57 146 2.22E-5 T 14-10-2018 Tharo_1425 48880dda150f64f9dce5ca2b193fe281 337 SUPERFAMILY SSF103481 162 294 8.5E-8 T 14-10-2018 Tharo_3126 4797e0d1638d20aa905924625ea3de41 433 SUPERFAMILY SSF56059 273 355 6.41E-5 T 14-10-2018 Tharo_3126 4797e0d1638d20aa905924625ea3de41 433 Pfam PF08886 Glutamate-cysteine ligase 17 419 2.0E-198 T 14-10-2018 IPR011718 Glutamate--cysteine ligase GshA Tharo_3126 4797e0d1638d20aa905924625ea3de41 433 TIGRFAM TIGR02049 gshA_ferroox: glutamate--cysteine ligase 17 422 1.7E-185 T 14-10-2018 IPR011718 Glutamate--cysteine ligase GshA Tharo_3126 4797e0d1638d20aa905924625ea3de41 433 Gene3D G3DSA:3.40.50.11280 65 204 7.8E-49 T 14-10-2018 Tharo_2234 5fc0863fecada661b5261ff217f7c7b1 101 Pfam PF01527 Transposase 7 80 9.0E-16 T 14-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 Tharo_2234 5fc0863fecada661b5261ff217f7c7b1 101 SUPERFAMILY SSF46689 6 99 1.47E-21 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_2234 5fc0863fecada661b5261ff217f7c7b1 101 Gene3D G3DSA:1.10.10.60 11 93 1.2E-11 T 14-10-2018 Tharo_0155 5fc0863fecada661b5261ff217f7c7b1 101 Pfam PF01527 Transposase 7 80 9.0E-16 T 14-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 Tharo_0155 5fc0863fecada661b5261ff217f7c7b1 101 SUPERFAMILY SSF46689 6 99 1.47E-21 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_0155 5fc0863fecada661b5261ff217f7c7b1 101 Gene3D G3DSA:1.10.10.60 11 93 1.2E-11 T 14-10-2018 Tharo_0231 5fc0863fecada661b5261ff217f7c7b1 101 Pfam PF01527 Transposase 7 80 9.0E-16 T 14-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 Tharo_0231 5fc0863fecada661b5261ff217f7c7b1 101 SUPERFAMILY SSF46689 6 99 1.47E-21 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_0231 5fc0863fecada661b5261ff217f7c7b1 101 Gene3D G3DSA:1.10.10.60 11 93 1.2E-11 T 14-10-2018 Tharo_0591 0348859a5095ae877f772082d8a1c79c 234 SUPERFAMILY SSF81606 15 230 1.44E-14 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Tharo_0591 0348859a5095ae877f772082d8a1c79c 234 Pfam PF13672 Protein phosphatase 2C 11 212 2.5E-37 T 14-10-2018 Tharo_0591 0348859a5095ae877f772082d8a1c79c 234 Gene3D G3DSA:3.60.40.10 24 234 3.8E-14 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Tharo_0285 37814819f927bc70d723579e8bd55831 499 SUPERFAMILY SSF53383 133 496 7.84E-84 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_0285 37814819f927bc70d723579e8bd55831 499 Gene3D G3DSA:3.40.640.10 127 489 6.7E-114 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_0285 37814819f927bc70d723579e8bd55831 499 Gene3D G3DSA:1.10.10.10 21 116 1.2E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0285 37814819f927bc70d723579e8bd55831 499 SMART SM00345 28 87 1.2E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_0285 37814819f927bc70d723579e8bd55831 499 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 87 1.7E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_0285 37814819f927bc70d723579e8bd55831 499 SUPERFAMILY SSF46785 19 95 1.95E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0285 37814819f927bc70d723579e8bd55831 499 Pfam PF00155 Aminotransferase class I and II 168 426 2.0E-18 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Tharo_0285 37814819f927bc70d723579e8bd55831 499 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 61 77 2.6E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_0285 37814819f927bc70d723579e8bd55831 499 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 61 2.6E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_1316 8bf4956a33d21bf42411a044a1cfd7c5 256 SUPERFAMILY SSF52540 10 245 3.76E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1316 8bf4956a33d21bf42411a044a1cfd7c5 256 Pfam PF00005 ABC transporter 28 174 4.9E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_1316 8bf4956a33d21bf42411a044a1cfd7c5 256 Gene3D G3DSA:3.40.50.300 8 247 6.2E-57 T 14-10-2018 Tharo_1316 8bf4956a33d21bf42411a044a1cfd7c5 256 SMART SM00382 37 244 2.7E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1316 8bf4956a33d21bf42411a044a1cfd7c5 256 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 227 245 2.6E-5 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal Tharo_1316 8bf4956a33d21bf42411a044a1cfd7c5 256 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_0197 4b0f38fd00fc3e5c85bcc9450a8d86b6 259 SUPERFAMILY SSF54909 3 113 1.93E-11 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel Tharo_0197 4b0f38fd00fc3e5c85bcc9450a8d86b6 259 Pfam PF07110 EthD domain 13 101 1.1E-7 T 14-10-2018 IPR009799 EthD domain Tharo_0197 4b0f38fd00fc3e5c85bcc9450a8d86b6 259 Pfam PF07110 EthD domain 151 238 5.7E-5 T 14-10-2018 IPR009799 EthD domain Tharo_0197 4b0f38fd00fc3e5c85bcc9450a8d86b6 259 Gene3D G3DSA:3.30.70.100 1 109 1.3E-6 T 14-10-2018 Tharo_0473 8a70d197aa24811ae60acb93712d4e06 347 Pfam PF00437 Type II/IV secretion system protein 12 265 1.3E-46 T 14-10-2018 IPR001482 Type II/IV secretion system protein Tharo_0473 8a70d197aa24811ae60acb93712d4e06 347 Gene3D G3DSA:3.40.50.300 101 347 3.6E-104 T 14-10-2018 Tharo_0473 8a70d197aa24811ae60acb93712d4e06 347 SUPERFAMILY SSF52540 5 335 1.77E-76 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0473 8a70d197aa24811ae60acb93712d4e06 347 Gene3D G3DSA:3.30.450.90 1 100 1.7E-38 T 14-10-2018 Tharo_0473 8a70d197aa24811ae60acb93712d4e06 347 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 14-10-2018 IPR001482 Type II/IV secretion system protein Tharo_0473 8a70d197aa24811ae60acb93712d4e06 347 SMART SM00382 122 289 0.0027 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0473 8a70d197aa24811ae60acb93712d4e06 347 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 343 5.3E-157 T 14-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 Tharo_0154 a503636f9da5c95061d0f03ad7107f39 260 SUPERFAMILY SSF109604 160 212 9.87E-8 T 14-10-2018 Tharo_0154 a503636f9da5c95061d0f03ad7107f39 260 Gene3D G3DSA:1.10.3210.10 155 248 1.1E-6 T 14-10-2018 Tharo_2162 f83ce9d069f7563df4408aaab2426549 67 Pfam PF04400 (Na+)-NQR maturation NqrM 22 63 4.1E-17 T 14-10-2018 IPR007495 (Na+)-NQR maturation factor NqrM Tharo_2526 6a767b1f1b511ba7a6153510c4a95880 578 Pfam PF00512 His Kinase A (phospho-acceptor) domain 331 398 5.4E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_2526 6a767b1f1b511ba7a6153510c4a95880 578 PRINTS PR00344 Bacterial sensor protein C-terminal signature 494 508 9.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2526 6a767b1f1b511ba7a6153510c4a95880 578 PRINTS PR00344 Bacterial sensor protein C-terminal signature 553 566 9.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2526 6a767b1f1b511ba7a6153510c4a95880 578 PRINTS PR00344 Bacterial sensor protein C-terminal signature 512 522 9.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2526 6a767b1f1b511ba7a6153510c4a95880 578 PRINTS PR00344 Bacterial sensor protein C-terminal signature 529 547 9.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2526 6a767b1f1b511ba7a6153510c4a95880 578 SUPERFAMILY SSF53850 18 224 1.59E-44 T 14-10-2018 Tharo_2526 6a767b1f1b511ba7a6153510c4a95880 578 SUPERFAMILY SSF47384 316 399 6.67E-22 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_2526 6a767b1f1b511ba7a6153510c4a95880 578 Gene3D G3DSA:3.40.190.10 32 225 3.0E-36 T 14-10-2018 Tharo_2526 6a767b1f1b511ba7a6153510c4a95880 578 Gene3D G3DSA:1.10.287.130 293 396 9.6E-29 T 14-10-2018 Tharo_2526 6a767b1f1b511ba7a6153510c4a95880 578 SUPERFAMILY SSF55874 387 569 3.14E-44 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2526 6a767b1f1b511ba7a6153510c4a95880 578 SMART SM00387 444 569 2.3E-39 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2526 6a767b1f1b511ba7a6153510c4a95880 578 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 444 568 7.4E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2526 6a767b1f1b511ba7a6153510c4a95880 578 SMART SM00388 330 398 3.3E-23 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_2526 6a767b1f1b511ba7a6153510c4a95880 578 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 18 225 1.7E-31 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Tharo_2526 6a767b1f1b511ba7a6153510c4a95880 578 SMART SM00062 17 240 5.0E-30 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Tharo_2526 6a767b1f1b511ba7a6153510c4a95880 578 Gene3D G3DSA:3.30.565.10 397 570 1.0E-47 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2526 6a767b1f1b511ba7a6153510c4a95880 578 Gene3D G3DSA:3.40.190.10 102 195 3.0E-36 T 14-10-2018 Tharo_2172 5b458eb4879ef054d92b6c9d6193b7be 202 SUPERFAMILY SSF51306 78 199 3.66E-35 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily Tharo_2172 5b458eb4879ef054d92b6c9d6193b7be 202 Pfam PF01726 LexA DNA binding domain 6 69 7.3E-23 T 14-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 Tharo_2172 5b458eb4879ef054d92b6c9d6193b7be 202 TIGRFAM TIGR00498 lexA: repressor LexA 6 200 6.9E-67 T 14-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 Tharo_2172 5b458eb4879ef054d92b6c9d6193b7be 202 Hamap MF_00015 LexA repressor [lexA]. 7 201 30.735 T 14-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 Tharo_2172 5b458eb4879ef054d92b6c9d6193b7be 202 Pfam PF00717 Peptidase S24-like 116 182 2.8E-14 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C Tharo_2172 5b458eb4879ef054d92b6c9d6193b7be 202 Gene3D G3DSA:1.10.10.10 6 74 2.5E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2172 5b458eb4879ef054d92b6c9d6193b7be 202 SUPERFAMILY SSF46785 7 73 3.31E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_2172 5b458eb4879ef054d92b6c9d6193b7be 202 Gene3D G3DSA:2.10.109.10 82 202 7.8E-42 T 14-10-2018 Tharo_2172 5b458eb4879ef054d92b6c9d6193b7be 202 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 152 164 3.8E-12 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 Tharo_2172 5b458eb4879ef054d92b6c9d6193b7be 202 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 124 135 3.8E-12 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 Tharo_2172 5b458eb4879ef054d92b6c9d6193b7be 202 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 113 123 3.8E-12 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 Tharo_3425 1e318466126b0d3bb5940e194152a636 143 Pfam PF00691 OmpA family 53 130 5.3E-10 T 14-10-2018 IPR006665 OmpA-like domain Tharo_3425 1e318466126b0d3bb5940e194152a636 143 SUPERFAMILY SSF103088 39 137 1.31E-14 T 14-10-2018 IPR036737 OmpA-like domain superfamily Tharo_3425 1e318466126b0d3bb5940e194152a636 143 Gene3D G3DSA:3.30.1330.60 25 140 2.3E-13 T 14-10-2018 IPR036737 OmpA-like domain superfamily Tharo_0193 b6686c706c5f6af106f7ed7157d05a0a 221 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 4 211 23.643 T 14-10-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 Tharo_0193 b6686c706c5f6af106f7ed7157d05a0a 221 Gene3D G3DSA:3.90.550.10 2 180 2.4E-44 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_0193 b6686c706c5f6af106f7ed7157d05a0a 221 Pfam PF01983 Guanylyl transferase CofC like 6 209 1.7E-26 T 14-10-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 Tharo_0193 b6686c706c5f6af106f7ed7157d05a0a 221 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 6 201 2.0E-44 T 14-10-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 Tharo_0193 b6686c706c5f6af106f7ed7157d05a0a 221 SUPERFAMILY SSF53448 4 202 1.0E-39 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_1550 a70bb6a7fa5762c53ed0d650469ca937 533 Pfam PF00501 AMP-binding enzyme 14 431 3.8E-93 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Tharo_1550 a70bb6a7fa5762c53ed0d650469ca937 533 SUPERFAMILY SSF56801 6 527 6.15E-140 T 14-10-2018 Tharo_1550 a70bb6a7fa5762c53ed0d650469ca937 533 TIGRFAM TIGR03098 ligase_PEP_1: acyl-CoA ligase (AMP-forming), exosortase A-associated 6 524 2.1E-240 T 14-10-2018 IPR017529 Acyl-CoA ligase (AMP-forming), exosortase system type 1 associated Tharo_1550 a70bb6a7fa5762c53ed0d650469ca937 533 ProSitePatterns PS00455 Putative AMP-binding domain signature. 171 182 - T 14-10-2018 IPR020845 AMP-binding, conserved site Tharo_1550 a70bb6a7fa5762c53ed0d650469ca937 533 Pfam PF13193 AMP-binding enzyme C-terminal domain 440 516 5.7E-12 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Tharo_1550 a70bb6a7fa5762c53ed0d650469ca937 533 Gene3D G3DSA:3.30.300.30 428 528 1.3E-25 T 14-10-2018 Tharo_1550 a70bb6a7fa5762c53ed0d650469ca937 533 Gene3D G3DSA:3.40.50.12780 3 427 1.6E-102 T 14-10-2018 Tharo_2448 c5e99b76f516df6029c2d8fe4121d6da 446 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 355 367 - T 14-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site Tharo_2448 c5e99b76f516df6029c2d8fe4121d6da 446 Pfam PF05195 Aminopeptidase P, N-terminal domain 13 128 4.6E-35 T 14-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 Tharo_2448 c5e99b76f516df6029c2d8fe4121d6da 446 SMART SM01011 8 143 3.0E-61 T 14-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 Tharo_2448 c5e99b76f516df6029c2d8fe4121d6da 446 Gene3D G3DSA:3.90.230.10 179 445 2.3E-96 T 14-10-2018 Tharo_2448 c5e99b76f516df6029c2d8fe4121d6da 446 PRINTS PR00599 Methionine aminopeptidase-1 signature 260 276 3.1E-6 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Tharo_2448 c5e99b76f516df6029c2d8fe4121d6da 446 PRINTS PR00599 Methionine aminopeptidase-1 signature 238 251 3.1E-6 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Tharo_2448 c5e99b76f516df6029c2d8fe4121d6da 446 PRINTS PR00599 Methionine aminopeptidase-1 signature 378 390 3.1E-6 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Tharo_2448 c5e99b76f516df6029c2d8fe4121d6da 446 Pfam PF00557 Metallopeptidase family M24 188 418 2.5E-63 T 14-10-2018 IPR000994 Peptidase M24 Tharo_2448 c5e99b76f516df6029c2d8fe4121d6da 446 SUPERFAMILY SSF55920 183 442 1.14E-82 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like Tharo_2448 c5e99b76f516df6029c2d8fe4121d6da 446 Gene3D G3DSA:3.40.350.10 10 178 7.6E-48 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal Tharo_2448 c5e99b76f516df6029c2d8fe4121d6da 446 SUPERFAMILY SSF53092 8 181 1.46E-51 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal Tharo_3401 adf366bb411f7d6116d5b06e15504211 548 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 357 536 1.8E-70 T 14-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_3401 adf366bb411f7d6116d5b06e15504211 548 Gene3D G3DSA:2.70.98.90 69 337 4.2E-88 T 14-10-2018 IPR038221 YidC, periplasmic domain superfamily Tharo_3401 adf366bb411f7d6116d5b06e15504211 548 PRINTS PR00701 60kDa inner membrane protein signature 502 525 4.2E-78 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Tharo_3401 adf366bb411f7d6116d5b06e15504211 548 PRINTS PR00701 60kDa inner membrane protein signature 165 185 4.2E-78 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Tharo_3401 adf366bb411f7d6116d5b06e15504211 548 PRINTS PR00701 60kDa inner membrane protein signature 221 239 4.2E-78 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Tharo_3401 adf366bb411f7d6116d5b06e15504211 548 PRINTS PR00701 60kDa inner membrane protein signature 2 23 4.2E-78 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Tharo_3401 adf366bb411f7d6116d5b06e15504211 548 PRINTS PR00701 60kDa inner membrane protein signature 256 271 4.2E-78 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Tharo_3401 adf366bb411f7d6116d5b06e15504211 548 PRINTS PR00701 60kDa inner membrane protein signature 328 348 4.2E-78 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Tharo_3401 adf366bb411f7d6116d5b06e15504211 548 PRINTS PR00701 60kDa inner membrane protein signature 466 488 4.2E-78 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Tharo_3401 adf366bb411f7d6116d5b06e15504211 548 PRINTS PR00701 60kDa inner membrane protein signature 78 99 4.2E-78 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Tharo_3401 adf366bb411f7d6116d5b06e15504211 548 PRINTS PR00701 60kDa inner membrane protein signature 419 442 4.2E-78 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Tharo_3401 adf366bb411f7d6116d5b06e15504211 548 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 538 25.41 T 14-10-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0032977 Tharo_3401 adf366bb411f7d6116d5b06e15504211 548 PRINTS PR01900 YidC translocation/secretion protein signature 491 515 9.7E-26 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Tharo_3401 adf366bb411f7d6116d5b06e15504211 548 PRINTS PR01900 YidC translocation/secretion protein signature 343 359 9.7E-26 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Tharo_3401 adf366bb411f7d6116d5b06e15504211 548 PRINTS PR01900 YidC translocation/secretion protein signature 472 487 9.7E-26 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Tharo_3401 adf366bb411f7d6116d5b06e15504211 548 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 3 356 3.8E-114 T 14-10-2018 IPR028053 Membrane insertase YidC, N-terminal Tharo_3401 adf366bb411f7d6116d5b06e15504211 548 Pfam PF14849 YidC periplasmic domain 73 347 3.9E-87 T 14-10-2018 IPR038210 Membrane insertase YidC, periplasmic domain Tharo_3401 adf366bb411f7d6116d5b06e15504211 548 Pfam PF02096 60Kd inner membrane protein 358 535 6.7E-60 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Tharo_3182 fbde869b03602bdb62391e8204c1997a 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 3.6E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_3182 fbde869b03602bdb62391e8204c1997a 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 1.8E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_3182 fbde869b03602bdb62391e8204c1997a 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.8E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_3182 fbde869b03602bdb62391e8204c1997a 205 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 93 201 8.8E-10 T 14-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal Tharo_3182 fbde869b03602bdb62391e8204c1997a 205 SUPERFAMILY SSF48498 101 193 1.72E-6 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Tharo_3182 fbde869b03602bdb62391e8204c1997a 205 Gene3D G3DSA:1.10.357.10 6 204 3.6E-35 T 14-10-2018 Tharo_3182 fbde869b03602bdb62391e8204c1997a 205 SUPERFAMILY SSF46689 11 82 6.14E-20 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_0524 d66c50b44864791276eeb303a75b0be2 353 Gene3D G3DSA:3.30.565.10 197 350 2.4E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_0524 d66c50b44864791276eeb303a75b0be2 353 Pfam PF00989 PAS fold 14 109 6.8E-6 T 14-10-2018 IPR013767 PAS fold GO:0006355 Tharo_0524 d66c50b44864791276eeb303a75b0be2 353 PRINTS PR00344 Bacterial sensor protein C-terminal signature 283 297 1.8E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_0524 d66c50b44864791276eeb303a75b0be2 353 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 348 1.8E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_0524 d66c50b44864791276eeb303a75b0be2 353 PRINTS PR00344 Bacterial sensor protein C-terminal signature 312 330 1.8E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_0524 d66c50b44864791276eeb303a75b0be2 353 SMART SM00388 133 198 9.7E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_0524 d66c50b44864791276eeb303a75b0be2 353 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 237 349 7.1E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_0524 d66c50b44864791276eeb303a75b0be2 353 SUPERFAMILY SSF55785 14 103 3.05E-7 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_0524 d66c50b44864791276eeb303a75b0be2 353 Pfam PF00512 His Kinase A (phospho-acceptor) domain 134 190 1.1E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_0524 d66c50b44864791276eeb303a75b0be2 353 Gene3D G3DSA:1.10.287.130 137 193 2.7E-14 T 14-10-2018 Tharo_0524 d66c50b44864791276eeb303a75b0be2 353 SUPERFAMILY SSF55874 200 348 4.85E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_0524 d66c50b44864791276eeb303a75b0be2 353 Gene3D G3DSA:3.30.450.20 12 116 1.5E-16 T 14-10-2018 Tharo_0524 d66c50b44864791276eeb303a75b0be2 353 SUPERFAMILY SSF47384 124 191 1.2E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_0524 d66c50b44864791276eeb303a75b0be2 353 SMART SM00387 236 351 9.3E-31 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1478 9b4341a191c523dadd528b1c4404bd82 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 74 3.5E-21 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_1478 9b4341a191c523dadd528b1c4404bd82 242 Pfam PF07702 UTRA domain 104 232 1.0E-30 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Tharo_1478 9b4341a191c523dadd528b1c4404bd82 242 SUPERFAMILY SSF46785 9 86 8.54E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1478 9b4341a191c523dadd528b1c4404bd82 242 Gene3D G3DSA:3.40.1410.10 83 241 1.5E-43 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily Tharo_1478 9b4341a191c523dadd528b1c4404bd82 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 3.5E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_1478 9b4341a191c523dadd528b1c4404bd82 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 3.5E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_1478 9b4341a191c523dadd528b1c4404bd82 242 SMART SM00866 94 236 4.1E-25 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Tharo_1478 9b4341a191c523dadd528b1c4404bd82 242 Gene3D G3DSA:1.10.10.10 7 75 4.0E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1478 9b4341a191c523dadd528b1c4404bd82 242 SUPERFAMILY SSF64288 63 240 2.83E-37 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily Tharo_1478 9b4341a191c523dadd528b1c4404bd82 242 SMART SM00345 15 74 1.1E-21 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_2505 3a800ca121271dccd5e11216ace8eb73 163 Gene3D G3DSA:3.30.70.1150 83 163 7.5E-30 T 14-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal Tharo_2505 3a800ca121271dccd5e11216ace8eb73 163 Pfam PF10369 Small subunit of acetolactate synthase 84 157 7.5E-27 T 14-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 Tharo_2505 3a800ca121271dccd5e11216ace8eb73 163 SUPERFAMILY SSF55021 1 76 4.04E-23 T 14-10-2018 Tharo_2505 3a800ca121271dccd5e11216ace8eb73 163 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 157 3.7E-64 T 14-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 Tharo_2505 3a800ca121271dccd5e11216ace8eb73 163 SUPERFAMILY SSF55021 79 162 1.68E-26 T 14-10-2018 Tharo_2505 3a800ca121271dccd5e11216ace8eb73 163 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 2.0E-35 T 14-10-2018 Tharo_2505 3a800ca121271dccd5e11216ace8eb73 163 Pfam PF13710 ACT domain 12 73 1.6E-15 T 14-10-2018 Tharo_2505 3a800ca121271dccd5e11216ace8eb73 163 Gene3D G3DSA:3.30.70.260 1 78 3.2E-35 T 14-10-2018 Tharo_0797 c61e5d8ed5a95a06b12c2a44cc1ec2bd 399 ProSitePatterns PS00737 Thiolases signature 2. 344 360 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 Tharo_0797 c61e5d8ed5a95a06b12c2a44cc1ec2bd 399 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 10 397 1.2E-131 T 14-10-2018 IPR002155 Thiolase GO:0016747 Tharo_0797 c61e5d8ed5a95a06b12c2a44cc1ec2bd 399 SUPERFAMILY SSF53901 277 398 7.33E-40 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_0797 c61e5d8ed5a95a06b12c2a44cc1ec2bd 399 Pfam PF02803 Thiolase, C-terminal domain 276 398 9.7E-40 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 Tharo_0797 c61e5d8ed5a95a06b12c2a44cc1ec2bd 399 Pfam PF00108 Thiolase, N-terminal domain 9 267 2.3E-69 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 Tharo_0797 c61e5d8ed5a95a06b12c2a44cc1ec2bd 399 PIRSF PIRSF000429 2 399 1.1E-120 T 14-10-2018 IPR002155 Thiolase GO:0016747 Tharo_0797 c61e5d8ed5a95a06b12c2a44cc1ec2bd 399 SUPERFAMILY SSF53901 7 274 6.76E-71 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_0797 c61e5d8ed5a95a06b12c2a44cc1ec2bd 399 ProSitePatterns PS00099 Thiolases active site. 380 393 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 Tharo_0797 c61e5d8ed5a95a06b12c2a44cc1ec2bd 399 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 90 108 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 Tharo_0797 c61e5d8ed5a95a06b12c2a44cc1ec2bd 399 Gene3D G3DSA:3.40.47.10 10 281 2.0E-136 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_0797 c61e5d8ed5a95a06b12c2a44cc1ec2bd 399 Gene3D G3DSA:3.40.47.10 132 395 2.0E-136 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_2138 7d93e0e4f636748b29b148f59ed9b8b3 63 SUPERFAMILY SSF160113 8 60 1.16E-12 T 14-10-2018 IPR036913 YegP-like superfamily Tharo_2138 7d93e0e4f636748b29b148f59ed9b8b3 63 Pfam PF07411 Domain of unknown function (DUF1508) 14 55 4.9E-11 T 14-10-2018 IPR010879 Domain of unknown function DUF1508 Tharo_2138 7d93e0e4f636748b29b148f59ed9b8b3 63 Gene3D G3DSA:3.30.160.160 10 53 1.7E-12 T 14-10-2018 Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 SMART SM00849 34 226 7.4E-28 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 SUPERFAMILY SSF57802 437 488 1.18E-17 T 14-10-2018 Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 Gene3D G3DSA:3.50.50.60 610 744 3.2E-77 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 647 665 1.6E-16 T 14-10-2018 Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 507 526 1.6E-16 T 14-10-2018 Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 732 748 1.6E-16 T 14-10-2018 Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 757 779 1.6E-16 T 14-10-2018 Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 602 620 1.6E-16 T 14-10-2018 Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 Gene3D G3DSA:3.40.50.360 252 394 1.8E-37 T 14-10-2018 IPR029039 Flavoprotein-like superfamily Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 506 528 2.0E-10 T 14-10-2018 Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 733 747 2.0E-10 T 14-10-2018 Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 772 779 2.0E-10 T 14-10-2018 Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 647 672 2.0E-10 T 14-10-2018 Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 SUPERFAMILY SSF52218 250 394 2.4E-34 T 14-10-2018 IPR029039 Flavoprotein-like superfamily Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 Gene3D G3DSA:3.50.50.60 508 780 3.2E-77 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 PRINTS PR00163 Rubredoxin signature 468 484 3.6E-5 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 PRINTS PR00163 Rubredoxin signature 438 454 3.6E-5 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 Pfam PF00301 Rubredoxin 439 484 3.5E-19 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 Pfam PF00753 Metallo-beta-lactamase superfamily 34 169 4.0E-10 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 Gene3D G3DSA:3.30.390.120 816 879 3.7E-8 T 14-10-2018 Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 507 779 8.8E-45 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 Gene3D G3DSA:2.20.28.10 437 490 2.4E-21 T 14-10-2018 Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 SUPERFAMILY SSF56281 8 284 3.28E-52 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 SUPERFAMILY SSF51905 499 806 3.49E-37 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 Pfam PF00258 Flavodoxin 255 374 2.8E-7 T 14-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 Tharo_0237 05dc8c7c6fa0c6e6d989b6edffeca3fa 883 Gene3D G3DSA:3.60.15.10 1 246 7.1E-101 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_2244 ef21bb614c9bdc6ed063a0794af2e837 447 Gene3D G3DSA:1.20.81.30 104 215 3.0E-26 T 14-10-2018 Tharo_2244 ef21bb614c9bdc6ed063a0794af2e837 447 PRINTS PR00812 Bacterial general secretion pathway protein F signature 411 425 2.1E-18 T 14-10-2018 IPR003004 GspF/PilC family Tharo_2244 ef21bb614c9bdc6ed063a0794af2e837 447 PRINTS PR00812 Bacterial general secretion pathway protein F signature 427 446 2.1E-18 T 14-10-2018 IPR003004 GspF/PilC family Tharo_2244 ef21bb614c9bdc6ed063a0794af2e837 447 PRINTS PR00812 Bacterial general secretion pathway protein F signature 109 121 2.1E-18 T 14-10-2018 IPR003004 GspF/PilC family Tharo_2244 ef21bb614c9bdc6ed063a0794af2e837 447 PRINTS PR00812 Bacterial general secretion pathway protein F signature 208 236 2.1E-18 T 14-10-2018 IPR003004 GspF/PilC family Tharo_2244 ef21bb614c9bdc6ed063a0794af2e837 447 Gene3D G3DSA:1.20.81.30 300 412 4.2E-24 T 14-10-2018 Tharo_2244 ef21bb614c9bdc6ed063a0794af2e837 447 Pfam PF00482 Type II secretion system (T2SS), protein F 116 236 1.4E-29 T 14-10-2018 IPR018076 Type II secretion system F domain Tharo_2244 ef21bb614c9bdc6ed063a0794af2e837 447 Pfam PF00482 Type II secretion system (T2SS), protein F 316 437 1.2E-25 T 14-10-2018 IPR018076 Type II secretion system F domain Tharo_3275 89a1263b6e6727a4bb2c9ee573f06ad1 363 SUPERFAMILY SSF55821 5 203 1.97E-86 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily Tharo_3275 89a1263b6e6727a4bb2c9ee573f06ad1 363 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 5 200 8.0E-74 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Tharo_3275 89a1263b6e6727a4bb2c9ee573f06ad1 363 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 2 204 37.873 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Tharo_3275 89a1263b6e6727a4bb2c9ee573f06ad1 363 PIRSF PIRSF001259 3 362 4.8E-108 T 14-10-2018 Tharo_3275 89a1263b6e6727a4bb2c9ee573f06ad1 363 Gene3D G3DSA:3.40.50.10990 208 361 9.0E-20 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Tharo_3275 89a1263b6e6727a4bb2c9ee573f06ad1 363 SUPERFAMILY SSF142695 205 360 7.06E-40 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Tharo_3275 89a1263b6e6727a4bb2c9ee573f06ad1 363 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 9 199 9.0E-84 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Tharo_3275 89a1263b6e6727a4bb2c9ee573f06ad1 363 Pfam PF00925 GTP cyclohydrolase II 209 360 3.1E-28 T 14-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Tharo_3275 89a1263b6e6727a4bb2c9ee573f06ad1 363 Gene3D G3DSA:3.90.870.10 1 207 1.2E-88 T 14-10-2018 Tharo_0253 e76272322cdb0814be5e529c5ee94c39 71 SUPERFAMILY SSF63562 1 68 2.09E-21 T 14-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Tharo_0253 e76272322cdb0814be5e529c5ee94c39 71 SMART SM01409 8 63 1.6E-15 T 14-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Tharo_0253 e76272322cdb0814be5e529c5ee94c39 71 Pfam PF01192 RNA polymerase Rpb6 8 61 2.0E-15 T 14-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Tharo_0253 e76272322cdb0814be5e529c5ee94c39 71 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 64 17.197 T 14-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_0253 e76272322cdb0814be5e529c5ee94c39 71 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 61 2.7E-22 T 14-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_0253 e76272322cdb0814be5e529c5ee94c39 71 Gene3D G3DSA:3.90.940.10 1 71 2.5E-22 T 14-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Tharo_2375 03d7c88c1eb35df6dfa261d5d0917205 186 PIRSF PIRSF016183 1 167 8.7E-59 T 14-10-2018 IPR006839 Ribosome-associated, YjgA Tharo_2375 03d7c88c1eb35df6dfa261d5d0917205 186 Pfam PF04751 Protein of unknown function (DUF615) 10 159 3.8E-52 T 14-10-2018 IPR006839 Ribosome-associated, YjgA Tharo_2375 03d7c88c1eb35df6dfa261d5d0917205 186 Gene3D G3DSA:1.10.60.30 96 168 2.3E-22 T 14-10-2018 Tharo_2375 03d7c88c1eb35df6dfa261d5d0917205 186 Gene3D G3DSA:1.10.60.30 20 94 3.5E-26 T 14-10-2018 Tharo_2375 03d7c88c1eb35df6dfa261d5d0917205 186 SUPERFAMILY SSF158710 20 162 1.44E-46 T 14-10-2018 IPR023153 PSPTO4464-like domain superfamily Tharo_1357 353c6ef3f89519a3bc1fba6d2d323bc8 141 SUPERFAMILY SSF109635 8 100 1.83E-32 T 14-10-2018 IPR037187 DksA, N-terminal domain superfamily Tharo_1357 353c6ef3f89519a3bc1fba6d2d323bc8 141 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 18 140 29.572 T 14-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 Tharo_1357 353c6ef3f89519a3bc1fba6d2d323bc8 141 Gene3D G3DSA:1.20.120.910 13 141 4.4E-38 T 14-10-2018 Tharo_1357 353c6ef3f89519a3bc1fba6d2d323bc8 141 PRINTS PR00618 DksA/TraR zinc finger signature 116 128 5.6E-5 T 14-10-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria Tharo_1357 353c6ef3f89519a3bc1fba6d2d323bc8 141 PRINTS PR00618 DksA/TraR zinc finger signature 104 115 5.6E-5 T 14-10-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria Tharo_1357 353c6ef3f89519a3bc1fba6d2d323bc8 141 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 104 128 - T 14-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site Tharo_1357 353c6ef3f89519a3bc1fba6d2d323bc8 141 SUPERFAMILY SSF57716 101 139 3.14E-10 T 14-10-2018 Tharo_1357 353c6ef3f89519a3bc1fba6d2d323bc8 141 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 22 130 2.1E-49 T 14-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 Tharo_1357 353c6ef3f89519a3bc1fba6d2d323bc8 141 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 99 133 6.0E-12 T 14-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 Tharo_1981 9463b1f9240e8479f32c2549ca21964c 469 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 371 463 9.0E-7 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 Tharo_1981 9463b1f9240e8479f32c2549ca21964c 469 SUPERFAMILY SSF54211 265 465 3.49E-39 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_1981 9463b1f9240e8479f32c2549ca21964c 469 SMART SM00382 90 254 5.7E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1981 9463b1f9240e8479f32c2549ca21964c 469 Hamap MF_01498 DNA repair protein RadA [radA]. 21 465 42.768 T 14-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 Tharo_1981 9463b1f9240e8479f32c2549ca21964c 469 SUPERFAMILY SSF52540 68 300 3.09E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1981 9463b1f9240e8479f32c2549ca21964c 469 Gene3D G3DSA:3.40.50.300 60 285 2.0E-38 T 14-10-2018 Tharo_1981 9463b1f9240e8479f32c2549ca21964c 469 PRINTS PR01874 DNA repair protein radA signature 10 34 5.3E-83 T 14-10-2018 Tharo_1981 9463b1f9240e8479f32c2549ca21964c 469 PRINTS PR01874 DNA repair protein radA signature 223 251 5.3E-83 T 14-10-2018 Tharo_1981 9463b1f9240e8479f32c2549ca21964c 469 PRINTS PR01874 DNA repair protein radA signature 184 208 5.3E-83 T 14-10-2018 Tharo_1981 9463b1f9240e8479f32c2549ca21964c 469 PRINTS PR01874 DNA repair protein radA signature 332 355 5.3E-83 T 14-10-2018 Tharo_1981 9463b1f9240e8479f32c2549ca21964c 469 PRINTS PR01874 DNA repair protein radA signature 82 110 5.3E-83 T 14-10-2018 Tharo_1981 9463b1f9240e8479f32c2549ca21964c 469 PRINTS PR01874 DNA repair protein radA signature 258 284 5.3E-83 T 14-10-2018 Tharo_1981 9463b1f9240e8479f32c2549ca21964c 469 Pfam PF13481 AAA domain 84 232 2.3E-15 T 14-10-2018 Tharo_1981 9463b1f9240e8479f32c2549ca21964c 469 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 461 3.3E-187 T 14-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 Tharo_1981 9463b1f9240e8479f32c2549ca21964c 469 Gene3D G3DSA:3.30.230.10 342 467 7.6E-17 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Tharo_0006 9c0ddc02ec57c86a3b572575f4e0cdd0 344 Gene3D G3DSA:3.30.40.60 223 311 4.8E-6 T 14-10-2018 Tharo_0006 9c0ddc02ec57c86a3b572575f4e0cdd0 344 Pfam PF01844 HNH endonuclease 256 305 3.7E-8 T 14-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 Tharo_0006 9c0ddc02ec57c86a3b572575f4e0cdd0 344 SMART SM00507 243 301 6.0E-6 T 14-10-2018 IPR003615 HNH nuclease Tharo_2252 8fb7c55f773db54fd728eb5e1594c68c 949 SMART SM00283 646 893 2.7E-90 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_2252 8fb7c55f773db54fd728eb5e1594c68c 949 SUPERFAMILY SSF55785 19 114 5.58E-27 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_2252 8fb7c55f773db54fd728eb5e1594c68c 949 SMART SM00086 80 121 5.8E-5 T 14-10-2018 IPR001610 PAC motif Tharo_2252 8fb7c55f773db54fd728eb5e1594c68c 949 SMART SM00091 433 498 150.0 T 14-10-2018 IPR000014 PAS domain Tharo_2252 8fb7c55f773db54fd728eb5e1594c68c 949 SMART SM00091 8 74 6.8E-4 T 14-10-2018 IPR000014 PAS domain Tharo_2252 8fb7c55f773db54fd728eb5e1594c68c 949 Gene3D G3DSA:1.20.1480.50 331 427 2.6E-9 T 14-10-2018 Tharo_2252 8fb7c55f773db54fd728eb5e1594c68c 949 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 21 115 5.5E-15 T 14-10-2018 IPR000014 PAS domain Tharo_2252 8fb7c55f773db54fd728eb5e1594c68c 949 Pfam PF08447 PAS fold 31 113 1.1E-15 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 Tharo_2252 8fb7c55f773db54fd728eb5e1594c68c 949 Gene3D G3DSA:3.30.450.20 429 549 7.1E-26 T 14-10-2018 Tharo_2252 8fb7c55f773db54fd728eb5e1594c68c 949 SUPERFAMILY SSF158472 371 418 6.41E-7 T 14-10-2018 Tharo_2252 8fb7c55f773db54fd728eb5e1594c68c 949 Gene3D G3DSA:1.10.287.950 594 895 6.5E-84 T 14-10-2018 Tharo_2252 8fb7c55f773db54fd728eb5e1594c68c 949 Gene3D G3DSA:3.30.450.20 15 139 6.3E-27 T 14-10-2018 Tharo_2252 8fb7c55f773db54fd728eb5e1594c68c 949 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 705 861 5.1E-52 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_2252 8fb7c55f773db54fd728eb5e1594c68c 949 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 821 850 7.1E-56 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_2252 8fb7c55f773db54fd728eb5e1594c68c 949 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 744 771 7.1E-56 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_2252 8fb7c55f773db54fd728eb5e1594c68c 949 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 773 802 7.1E-56 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_2252 8fb7c55f773db54fd728eb5e1594c68c 949 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 667 696 7.1E-56 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_2252 8fb7c55f773db54fd728eb5e1594c68c 949 SMART SM00304 593 645 0.9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_2252 8fb7c55f773db54fd728eb5e1594c68c 949 SMART SM00304 371 423 5.3E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_2252 8fb7c55f773db54fd728eb5e1594c68c 949 SUPERFAMILY SSF58104 613 894 2.53E-72 T 14-10-2018 Tharo_1413 8f8c10b0a55667dd401aa29cc126b83a 365 Gene3D G3DSA:3.40.50.970 1 350 1.3E-111 T 14-10-2018 Tharo_1413 8f8c10b0a55667dd401aa29cc126b83a 365 Pfam PF00676 Dehydrogenase E1 component 39 320 8.6E-82 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 Tharo_1413 8f8c10b0a55667dd401aa29cc126b83a 365 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 11 349 1.9E-142 T 14-10-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 Tharo_1413 8f8c10b0a55667dd401aa29cc126b83a 365 SUPERFAMILY SSF52518 6 351 1.73E-101 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_2647 6c348e5adef1504ec2ab5aabd3aeabb9 274 Pfam PF13662 Toprim domain 187 259 1.6E-8 T 14-10-2018 IPR006171 TOPRIM domain Tharo_2647 6c348e5adef1504ec2ab5aabd3aeabb9 274 SMART SM00493 186 264 0.0034 T 14-10-2018 IPR006171 TOPRIM domain Tharo_2746 dc01eee49b74f30352374cba9ff32b86 643 SMART SM00388 264 329 1.5E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_2746 dc01eee49b74f30352374cba9ff32b86 643 Pfam PF00512 His Kinase A (phospho-acceptor) domain 264 329 2.3E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_2746 dc01eee49b74f30352374cba9ff32b86 643 SUPERFAMILY SSF55874 318 486 6.81E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2746 dc01eee49b74f30352374cba9ff32b86 643 SMART SM00304 186 238 9.1E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_2746 dc01eee49b74f30352374cba9ff32b86 643 SUPERFAMILY SSF52172 503 624 3.84E-23 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_2746 dc01eee49b74f30352374cba9ff32b86 643 Pfam PF00072 Response regulator receiver domain 506 619 6.8E-14 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2746 dc01eee49b74f30352374cba9ff32b86 643 Gene3D G3DSA:1.10.287.130 250 331 5.5E-19 T 14-10-2018 Tharo_2746 dc01eee49b74f30352374cba9ff32b86 643 Gene3D G3DSA:3.40.50.2300 502 632 3.5E-21 T 14-10-2018 Tharo_2746 dc01eee49b74f30352374cba9ff32b86 643 SUPERFAMILY SSF47384 249 329 3.53E-18 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_2746 dc01eee49b74f30352374cba9ff32b86 643 SMART SM00387 373 484 5.3E-31 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2746 dc01eee49b74f30352374cba9ff32b86 643 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 375 483 1.8E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2746 dc01eee49b74f30352374cba9ff32b86 643 Gene3D G3DSA:3.30.565.10 337 484 7.7E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2746 dc01eee49b74f30352374cba9ff32b86 643 PRINTS PR00344 Bacterial sensor protein C-terminal signature 468 481 2.4E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2746 dc01eee49b74f30352374cba9ff32b86 643 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 462 2.4E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2746 dc01eee49b74f30352374cba9ff32b86 643 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 437 2.4E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2746 dc01eee49b74f30352374cba9ff32b86 643 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 423 2.4E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2746 dc01eee49b74f30352374cba9ff32b86 643 Pfam PF09984 Uncharacterised signal transduction histidine kinase domain (DUF2222) 23 152 2.4E-8 T 14-10-2018 IPR019247 Histidine kinase BarA, N-terminal Tharo_2746 dc01eee49b74f30352374cba9ff32b86 643 Gene3D G3DSA:1.20.1480.50 152 245 4.6E-5 T 14-10-2018 Tharo_2746 dc01eee49b74f30352374cba9ff32b86 643 SMART SM00448 504 619 2.9E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2207 a43d05d728848a023c629eea6bf52cfd 213 Pfam PF00633 Helix-hairpin-helix motif 102 130 1.6E-5 T 14-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 Tharo_2207 a43d05d728848a023c629eea6bf52cfd 213 Hamap MF_00942 Endonuclease III [nth]. 1 212 36.822 T 14-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 Tharo_2207 a43d05d728848a023c629eea6bf52cfd 213 SUPERFAMILY SSF48150 6 211 3.3E-71 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 Tharo_2207 a43d05d728848a023c629eea6bf52cfd 213 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 190 206 3.1E-5 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 Tharo_2207 a43d05d728848a023c629eea6bf52cfd 213 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 37 171 6.7E-18 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Tharo_2207 a43d05d728848a023c629eea6bf52cfd 213 SMART SM00478 41 188 3.1E-53 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Tharo_2207 a43d05d728848a023c629eea6bf52cfd 213 PIRSF PIRSF001435 1 213 1.3E-49 T 14-10-2018 Tharo_2207 a43d05d728848a023c629eea6bf52cfd 213 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 190 206 - T 14-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 Tharo_2207 a43d05d728848a023c629eea6bf52cfd 213 TIGRFAM TIGR01083 nth: endonuclease III 8 197 1.1E-78 T 14-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 Tharo_2207 a43d05d728848a023c629eea6bf52cfd 213 SMART SM00525 189 209 1.6E-4 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 Tharo_2207 a43d05d728848a023c629eea6bf52cfd 213 Gene3D G3DSA:1.10.340.30 24 135 1.2E-74 T 14-10-2018 Tharo_2207 a43d05d728848a023c629eea6bf52cfd 213 Gene3D G3DSA:1.10.1670.10 14 206 1.2E-74 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 Tharo_1823 0252ae03974e811645670305c51e08a2 561 SMART SM00388 346 411 1.6E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1823 0252ae03974e811645670305c51e08a2 561 SUPERFAMILY SSF55874 410 556 1.57E-41 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1823 0252ae03974e811645670305c51e08a2 561 Gene3D G3DSA:1.10.287.130 340 409 8.3E-14 T 14-10-2018 Tharo_1823 0252ae03974e811645670305c51e08a2 561 SMART SM00387 452 558 7.3E-35 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1823 0252ae03974e811645670305c51e08a2 561 Pfam PF00512 His Kinase A (phospho-acceptor) domain 347 407 5.5E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1823 0252ae03974e811645670305c51e08a2 561 PRINTS PR00344 Bacterial sensor protein C-terminal signature 542 555 3.0E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1823 0252ae03974e811645670305c51e08a2 561 PRINTS PR00344 Bacterial sensor protein C-terminal signature 507 517 3.0E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1823 0252ae03974e811645670305c51e08a2 561 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 536 3.0E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1823 0252ae03974e811645670305c51e08a2 561 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 503 3.0E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1823 0252ae03974e811645670305c51e08a2 561 Pfam PF00672 HAMP domain 285 333 4.6E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_1823 0252ae03974e811645670305c51e08a2 561 Gene3D G3DSA:1.20.1480.50 255 339 3.5E-9 T 14-10-2018 Tharo_1823 0252ae03974e811645670305c51e08a2 561 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 453 557 2.2E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1823 0252ae03974e811645670305c51e08a2 561 SUPERFAMILY SSF158472 286 334 2.88E-7 T 14-10-2018 Tharo_1823 0252ae03974e811645670305c51e08a2 561 Gene3D G3DSA:3.30.565.10 413 560 6.0E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1823 0252ae03974e811645670305c51e08a2 561 SUPERFAMILY SSF47384 340 409 6.28E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_1823 0252ae03974e811645670305c51e08a2 561 SMART SM00304 284 336 5.8E-12 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_0468 dbe7be02a27fbe5a8d3c4713b01d8f8d 205 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 84 95 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_0468 dbe7be02a27fbe5a8d3c4713b01d8f8d 205 Gene3D G3DSA:3.30.70.20 2 167 4.2E-36 T 14-10-2018 Tharo_0468 dbe7be02a27fbe5a8d3c4713b01d8f8d 205 Gene3D G3DSA:3.30.70.20 58 116 4.2E-36 T 14-10-2018 Tharo_0468 dbe7be02a27fbe5a8d3c4713b01d8f8d 205 SUPERFAMILY SSF54862 3 178 7.64E-49 T 14-10-2018 Tharo_0468 dbe7be02a27fbe5a8d3c4713b01d8f8d 205 Pfam PF13247 4Fe-4S dicluster domain 49 162 1.6E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_1048 9ca4ed3957d4466d60ca28cb471332eb 549 Gene3D G3DSA:3.30.260.10 136 410 3.4E-241 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily Tharo_1048 9ca4ed3957d4466d60ca28cb471332eb 549 Gene3D G3DSA:1.10.560.10 8 521 3.4E-241 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily Tharo_1048 9ca4ed3957d4466d60ca28cb471332eb 549 SUPERFAMILY SSF48592 7 521 2.06E-78 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily Tharo_1048 9ca4ed3957d4466d60ca28cb471332eb 549 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 521 1.6E-100 T 14-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 Tharo_1048 9ca4ed3957d4466d60ca28cb471332eb 549 SUPERFAMILY SSF54849 137 203 3.2E-25 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily Tharo_1048 9ca4ed3957d4466d60ca28cb471332eb 549 SUPERFAMILY SSF52029 184 376 4.93E-84 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily Tharo_1048 9ca4ed3957d4466d60ca28cb471332eb 549 Gene3D G3DSA:3.50.7.10 192 372 3.4E-241 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily Tharo_1048 9ca4ed3957d4466d60ca28cb471332eb 549 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 6.1E-260 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Tharo_1048 9ca4ed3957d4466d60ca28cb471332eb 549 PRINTS PR00298 60kDa chaperonin signature 398 419 2.5E-74 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Tharo_1048 9ca4ed3957d4466d60ca28cb471332eb 549 PRINTS PR00298 60kDa chaperonin signature 268 291 2.5E-74 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Tharo_1048 9ca4ed3957d4466d60ca28cb471332eb 549 PRINTS PR00298 60kDa chaperonin signature 350 375 2.5E-74 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Tharo_1048 9ca4ed3957d4466d60ca28cb471332eb 549 PRINTS PR00298 60kDa chaperonin signature 83 110 2.5E-74 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Tharo_1048 9ca4ed3957d4466d60ca28cb471332eb 549 PRINTS PR00298 60kDa chaperonin signature 27 53 2.5E-74 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Tharo_1048 9ca4ed3957d4466d60ca28cb471332eb 549 Hamap MF_00600 60 kDa chaperonin [groL]. 2 549 41.827 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Tharo_1048 9ca4ed3957d4466d60ca28cb471332eb 549 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 14-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Tharo_2222 26bc79cd47f6475bfca7be1e633f85fa 349 Gene3D G3DSA:2.102.10.10 1 126 1.8E-31 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Tharo_2222 26bc79cd47f6475bfca7be1e633f85fa 349 SUPERFAMILY SSF55961 116 340 2.4E-56 T 14-10-2018 Tharo_2222 26bc79cd47f6475bfca7be1e633f85fa 349 SUPERFAMILY SSF50022 3 117 1.28E-30 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Tharo_2222 26bc79cd47f6475bfca7be1e633f85fa 349 Pfam PF00355 Rieske [2Fe-2S] domain 7 87 3.4E-16 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Tharo_2222 26bc79cd47f6475bfca7be1e633f85fa 349 Gene3D G3DSA:3.30.530.90 128 346 4.3E-65 T 14-10-2018 Tharo_3437 b86a8f30eb5c80abbee6daef11040ad7 408 Gene3D G3DSA:1.20.1440.30 130 272 2.4E-31 T 14-10-2018 Tharo_3437 b86a8f30eb5c80abbee6daef11040ad7 408 Gene3D G3DSA:3.40.1660.10 16 397 2.4E-31 T 14-10-2018 Tharo_3437 b86a8f30eb5c80abbee6daef11040ad7 408 PIRSF PIRSF000880 1 408 5.3E-234 T 14-10-2018 IPR016273 Erythromycin esterase, proteobacteria Tharo_3437 b86a8f30eb5c80abbee6daef11040ad7 408 SUPERFAMILY SSF159501 17 399 2.51E-55 T 14-10-2018 Tharo_3437 b86a8f30eb5c80abbee6daef11040ad7 408 Gene3D G3DSA:3.30.1870.10 59 129 2.4E-31 T 14-10-2018 Tharo_3437 b86a8f30eb5c80abbee6daef11040ad7 408 Pfam PF05139 Erythromycin esterase 57 398 6.7E-28 T 14-10-2018 IPR007815 Erythromycin esterase GO:0046677 Tharo_2084 ccc5c0654f137c667ed1b182dc831004 177 Gene3D G3DSA:1.20.1280.20 86 175 4.3E-23 T 14-10-2018 IPR036386 HscB, C-terminal domain superfamily GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 Tharo_2084 ccc5c0654f137c667ed1b182dc831004 177 Gene3D G3DSA:1.10.287.110 8 85 2.6E-21 T 14-10-2018 IPR036869 Chaperone J-domain superfamily Tharo_2084 ccc5c0654f137c667ed1b182dc831004 177 SUPERFAMILY SSF47144 84 172 7.45E-24 T 14-10-2018 IPR036386 HscB, C-terminal domain superfamily GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 Tharo_2084 ccc5c0654f137c667ed1b182dc831004 177 Hamap MF_00682 Co-chaperone protein HscB [hscB]. 7 176 23.905 T 14-10-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 Tharo_2084 ccc5c0654f137c667ed1b182dc831004 177 TIGRFAM TIGR00714 hscB: Fe-S protein assembly co-chaperone HscB 19 170 1.8E-31 T 14-10-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 Tharo_2084 ccc5c0654f137c667ed1b182dc831004 177 SUPERFAMILY SSF46565 8 80 2.49E-15 T 14-10-2018 IPR036869 Chaperone J-domain superfamily Tharo_2084 ccc5c0654f137c667ed1b182dc831004 177 SMART SM00271 7 72 0.0087 T 14-10-2018 IPR001623 DnaJ domain Tharo_2084 ccc5c0654f137c667ed1b182dc831004 177 Pfam PF07743 HSCB C-terminal oligomerisation domain 93 169 5.7E-21 T 14-10-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 Tharo_2356 49a14513fb4cf8314c3689c50a0801af 365 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 1 365 38.128 T 14-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 Tharo_2356 49a14513fb4cf8314c3689c50a0801af 365 Gene3D G3DSA:3.40.50.620 1 210 1.2E-89 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_2356 49a14513fb4cf8314c3689c50a0801af 365 Pfam PF03054 tRNA methyl transferase 1 364 2.4E-133 T 14-10-2018 Tharo_2356 49a14513fb4cf8314c3689c50a0801af 365 SUPERFAMILY SSF52402 1 243 2.09E-55 T 14-10-2018 Tharo_2356 49a14513fb4cf8314c3689c50a0801af 365 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1 364 9.1E-131 T 14-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 Tharo_2356 49a14513fb4cf8314c3689c50a0801af 365 Gene3D G3DSA:2.30.30.280 211 285 6.2E-24 T 14-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 Tharo_2356 49a14513fb4cf8314c3689c50a0801af 365 Gene3D G3DSA:2.40.30.10 286 365 3.8E-23 T 14-10-2018 Tharo_2992 6085cf00de48cafff15534f9f302b479 872 SMART SM00091 337 405 4.0E-5 T 14-10-2018 IPR000014 PAS domain Tharo_2992 6085cf00de48cafff15534f9f302b479 872 SMART SM00091 587 650 45.0 T 14-10-2018 IPR000014 PAS domain Tharo_2992 6085cf00de48cafff15534f9f302b479 872 SMART SM00091 460 529 1.7 T 14-10-2018 IPR000014 PAS domain Tharo_2992 6085cf00de48cafff15534f9f302b479 872 SUPERFAMILY SSF55785 344 455 2.62E-19 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_2992 6085cf00de48cafff15534f9f302b479 872 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 707 871 1.4E-48 T 14-10-2018 IPR000160 GGDEF domain Tharo_2992 6085cf00de48cafff15534f9f302b479 872 SMART SM00086 659 700 320.0 T 14-10-2018 IPR001610 PAC motif Tharo_2992 6085cf00de48cafff15534f9f302b479 872 SMART SM00086 412 455 1.8E-6 T 14-10-2018 IPR001610 PAC motif Tharo_2992 6085cf00de48cafff15534f9f302b479 872 SMART SM00086 534 575 180.0 T 14-10-2018 IPR001610 PAC motif Tharo_2992 6085cf00de48cafff15534f9f302b479 872 Gene3D G3DSA:3.30.450.20 46 194 4.5E-25 T 14-10-2018 Tharo_2992 6085cf00de48cafff15534f9f302b479 872 Pfam PF02743 Cache domain 49 243 4.0E-15 T 14-10-2018 IPR033479 Double Cache domain 1 Tharo_2992 6085cf00de48cafff15534f9f302b479 872 SMART SM00267 700 871 1.7E-67 T 14-10-2018 IPR000160 GGDEF domain Tharo_2992 6085cf00de48cafff15534f9f302b479 872 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 458 582 1.4E-10 T 14-10-2018 IPR000014 PAS domain Tharo_2992 6085cf00de48cafff15534f9f302b479 872 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 361 456 1.2E-6 T 14-10-2018 IPR000014 PAS domain Tharo_2992 6085cf00de48cafff15534f9f302b479 872 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 591 707 1.0E-5 T 14-10-2018 IPR000014 PAS domain Tharo_2992 6085cf00de48cafff15534f9f302b479 872 SUPERFAMILY SSF55785 465 578 2.62E-13 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_2992 6085cf00de48cafff15534f9f302b479 872 Gene3D G3DSA:3.30.450.20 462 577 2.0E-15 T 14-10-2018 Tharo_2992 6085cf00de48cafff15534f9f302b479 872 Gene3D G3DSA:3.30.450.20 331 450 9.6E-28 T 14-10-2018 Tharo_2992 6085cf00de48cafff15534f9f302b479 872 Gene3D G3DSA:3.30.70.270 702 871 1.7E-56 T 14-10-2018 Tharo_2992 6085cf00de48cafff15534f9f302b479 872 SUPERFAMILY SSF55073 716 870 1.18E-45 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_2992 6085cf00de48cafff15534f9f302b479 872 Pfam PF08447 PAS fold 360 448 2.0E-23 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 Tharo_2992 6085cf00de48cafff15534f9f302b479 872 Pfam PF00990 Diguanylate cyclase, GGDEF domain 711 867 3.3E-48 T 14-10-2018 IPR000160 GGDEF domain Tharo_2992 6085cf00de48cafff15534f9f302b479 872 Gene3D G3DSA:3.30.450.20 578 701 3.6E-11 T 14-10-2018 Tharo_2992 6085cf00de48cafff15534f9f302b479 872 Pfam PF08448 PAS fold 466 577 3.4E-7 T 14-10-2018 IPR013656 PAS fold-4 Tharo_2992 6085cf00de48cafff15534f9f302b479 872 Gene3D G3DSA:3.30.450.20 202 284 1.0E-8 T 14-10-2018 Tharo_2992 6085cf00de48cafff15534f9f302b479 872 SUPERFAMILY SSF55785 572 698 4.89E-11 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_1938 b0bfa65e4f360baf68537d316384a621 430 Gene3D G3DSA:3.30.930.10 105 428 9.1E-115 T 14-10-2018 Tharo_1938 b0bfa65e4f360baf68537d316384a621 430 PRINTS PR00981 Seryl-tRNA synthetase signature 355 371 1.1E-32 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Tharo_1938 b0bfa65e4f360baf68537d316384a621 430 PRINTS PR00981 Seryl-tRNA synthetase signature 268 280 1.1E-32 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Tharo_1938 b0bfa65e4f360baf68537d316384a621 430 PRINTS PR00981 Seryl-tRNA synthetase signature 280 293 1.1E-32 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Tharo_1938 b0bfa65e4f360baf68537d316384a621 430 PRINTS PR00981 Seryl-tRNA synthetase signature 337 353 1.1E-32 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Tharo_1938 b0bfa65e4f360baf68537d316384a621 430 PRINTS PR00981 Seryl-tRNA synthetase signature 320 333 1.1E-32 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Tharo_1938 b0bfa65e4f360baf68537d316384a621 430 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 420 4.7E-160 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Tharo_1938 b0bfa65e4f360baf68537d316384a621 430 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 425 39.879 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Tharo_1938 b0bfa65e4f360baf68537d316384a621 430 SUPERFAMILY SSF55681 116 423 1.18E-99 T 14-10-2018 Tharo_1938 b0bfa65e4f360baf68537d316384a621 430 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 224 403 2.9E-35 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_1938 b0bfa65e4f360baf68537d316384a621 430 Gene3D G3DSA:1.10.287.40 1 104 2.1E-22 T 14-10-2018 Tharo_1938 b0bfa65e4f360baf68537d316384a621 430 SUPERFAMILY SSF46589 1 112 3.09E-30 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 Tharo_1938 b0bfa65e4f360baf68537d316384a621 430 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 4.3E-31 T 14-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 Tharo_1938 b0bfa65e4f360baf68537d316384a621 430 PIRSF PIRSF001529 1 429 9.0E-176 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Tharo_3019 43ae0cd78ed070669f2bef4600ab52a4 224 TIGRFAM TIGR01876 cas_Cas5d: CRISPR-associated protein Cas5, subtype I-C/DVULG 9 222 4.1E-56 T 14-10-2018 IPR010155 CRISPR pre-crRNA endoribonuclease Cas5d GO:0004519|GO:0051607 Tharo_3019 43ae0cd78ed070669f2bef4600ab52a4 224 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 8 46 1.2E-15 T 14-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal Tharo_3019 43ae0cd78ed070669f2bef4600ab52a4 224 Gene3D G3DSA:3.30.70.2660 1 224 6.0E-102 T 14-10-2018 Tharo_3019 43ae0cd78ed070669f2bef4600ab52a4 224 PIRSF PIRSF029950 1 224 3.1E-93 T 14-10-2018 IPR010155 CRISPR pre-crRNA endoribonuclease Cas5d GO:0004519|GO:0051607 Tharo_3019 43ae0cd78ed070669f2bef4600ab52a4 224 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 8 215 4.0E-46 T 14-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 Tharo_0405 d90bf4b94320bde98e3fa64895f13478 695 Gene3D G3DSA:3.40.30.60 363 506 4.4E-49 T 14-10-2018 Tharo_0405 d90bf4b94320bde98e3fa64895f13478 695 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 25 690 4.4E-269 T 14-10-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 Tharo_0405 d90bf4b94320bde98e3fa64895f13478 695 Pfam PF00771 FHIPEP family 31 682 1.0E-264 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Tharo_0405 d90bf4b94320bde98e3fa64895f13478 695 Gene3D G3DSA:1.10.490.80 598 690 6.1E-6 T 14-10-2018 Tharo_0405 d90bf4b94320bde98e3fa64895f13478 695 Gene3D G3DSA:1.10.8.540 507 595 6.3E-23 T 14-10-2018 Tharo_0405 d90bf4b94320bde98e3fa64895f13478 695 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 147 170 - T 14-10-2018 IPR025505 FHIPEP conserved site Tharo_0405 d90bf4b94320bde98e3fa64895f13478 695 PIRSF PIRSF005419 9 694 1.3E-243 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Tharo_0405 d90bf4b94320bde98e3fa64895f13478 695 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 191 208 8.0E-56 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Tharo_0405 d90bf4b94320bde98e3fa64895f13478 695 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 38 51 8.0E-56 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Tharo_0405 d90bf4b94320bde98e3fa64895f13478 695 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 75 94 8.0E-56 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Tharo_0405 d90bf4b94320bde98e3fa64895f13478 695 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 242 256 8.0E-56 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Tharo_0405 d90bf4b94320bde98e3fa64895f13478 695 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 142 158 8.0E-56 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Tharo_0405 d90bf4b94320bde98e3fa64895f13478 695 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 161 179 8.0E-56 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Tharo_3197 cdbd5d4a8f60c101f44b6346ad130c2c 321 PIRSF PIRSF005355 16 321 6.2E-52 T 14-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 Tharo_3197 cdbd5d4a8f60c101f44b6346ad130c2c 321 Pfam PF01040 UbiA prenyltransferase family 41 282 3.9E-28 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 Tharo_1134 9c98d88089395548ad3bb9698058430c 473 TIGRFAM TIGR03225 benzo_boxB: benzoyl-CoA oxygenase, B subunit 2 472 7.8E-279 T 14-10-2018 IPR017635 Benzoyl-CoA oxygenase, B subunit KEGG: 00362+1.14.13.208|MetaCyc: PWY-1361 Tharo_1134 9c98d88089395548ad3bb9698058430c 473 SUPERFAMILY SSF47240 105 323 1.23E-48 T 14-10-2018 IPR009078 Ferritin-like superfamily Tharo_1134 9c98d88089395548ad3bb9698058430c 473 Gene3D G3DSA:1.10.620.20 1 473 3.9E-247 T 14-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 Tharo_0529 d01d003bf49f685181276e01cb46a214 366 Hamap MF_00569 Quinolinate synthase A [nadA]. 15 365 49.448 T 14-10-2018 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 Tharo_0529 d01d003bf49f685181276e01cb46a214 366 SUPERFAMILY SSF142754 25 364 1.83E-94 T 14-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 Tharo_0529 d01d003bf49f685181276e01cb46a214 366 Gene3D G3DSA:3.40.50.10800 226 316 2.0E-79 T 14-10-2018 Tharo_0529 d01d003bf49f685181276e01cb46a214 366 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 16 366 1.3E-91 T 14-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 Tharo_0529 d01d003bf49f685181276e01cb46a214 366 Gene3D G3DSA:3.40.50.10800 104 363 2.0E-79 T 14-10-2018 Tharo_0529 d01d003bf49f685181276e01cb46a214 366 Gene3D G3DSA:3.40.50.10800 32 346 2.0E-79 T 14-10-2018 Tharo_0529 d01d003bf49f685181276e01cb46a214 366 Pfam PF02445 Quinolinate synthetase A protein 22 364 3.0E-102 T 14-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 Tharo_2896 527f8c6f7d9980b80198773956033534 68 Pfam PF05015 RelE-like toxin of type II toxin-antitoxin system HigB 2 68 1.7E-14 T 14-10-2018 IPR007711 Toxin HigB-1 Tharo_2896 527f8c6f7d9980b80198773956033534 68 SUPERFAMILY SSF143011 3 68 2.55E-10 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_2896 527f8c6f7d9980b80198773956033534 68 Gene3D G3DSA:3.30.2310.20 1 68 1.9E-23 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_1571 dfd4d4bb2d5607516933172e6dd10536 363 SUPERFAMILY SSF117916 1 83 4.25E-18 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Tharo_1571 dfd4d4bb2d5607516933172e6dd10536 363 Gene3D G3DSA:3.40.50.300 89 339 7.7E-87 T 14-10-2018 Tharo_1571 dfd4d4bb2d5607516933172e6dd10536 363 ProSitePatterns PS01215 Mrp family signature. 204 220 - T 14-10-2018 IPR000808 Mrp, conserved site GO:0005524 Tharo_1571 dfd4d4bb2d5607516933172e6dd10536 363 Hamap MF_02040 Iron-sulfur cluster carrier protein. 92 341 38.443 T 14-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein Tharo_1571 dfd4d4bb2d5607516933172e6dd10536 363 SUPERFAMILY SSF52540 91 325 1.55E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1571 dfd4d4bb2d5607516933172e6dd10536 363 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 97 340 1.1E-104 T 14-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 Tharo_1571 dfd4d4bb2d5607516933172e6dd10536 363 Gene3D G3DSA:3.30.300.130 3 88 1.5E-10 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Tharo_1571 dfd4d4bb2d5607516933172e6dd10536 363 Pfam PF01883 Iron-sulfur cluster assembly protein 6 77 7.3E-24 T 14-10-2018 IPR002744 MIP18 family-like Tharo_0088 54634ab1847d1cd426bfe47ffd5584e7 376 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 271 277 - T 14-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 Tharo_0088 54634ab1847d1cd426bfe47ffd5584e7 376 Gene3D G3DSA:3.20.20.70 2 376 8.0E-134 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_0088 54634ab1847d1cd426bfe47ffd5584e7 376 Pfam PF01070 FMN-dependent dehydrogenase 12 374 1.9E-131 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 Tharo_0088 54634ab1847d1cd426bfe47ffd5584e7 376 PIRSF PIRSF000138 1 376 5.1E-131 T 14-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 Tharo_0088 54634ab1847d1cd426bfe47ffd5584e7 376 SUPERFAMILY SSF51395 3 373 8.55E-97 T 14-10-2018 Tharo_2563 1ccbde847cc86b016dbdc8e8726a893c 671 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 20 200 1.7E-48 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 Tharo_2563 1ccbde847cc86b016dbdc8e8726a893c 671 SUPERFAMILY SSF51735 19 200 1.05E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_2563 1ccbde847cc86b016dbdc8e8726a893c 671 Gene3D G3DSA:1.10.1040.50 206 366 1.4E-7 T 14-10-2018 Tharo_2563 1ccbde847cc86b016dbdc8e8726a893c 671 Gene3D G3DSA:3.90.226.10 379 599 6.0E-48 T 14-10-2018 Tharo_2563 1ccbde847cc86b016dbdc8e8726a893c 671 SUPERFAMILY SSF52096 381 668 4.44E-54 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_2563 1ccbde847cc86b016dbdc8e8726a893c 671 Gene3D G3DSA:3.40.50.720 11 201 7.0E-52 T 14-10-2018 Tharo_2563 1ccbde847cc86b016dbdc8e8726a893c 671 Pfam PF00378 Enoyl-CoA hydratase/isomerase 389 582 2.6E-35 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Tharo_2563 1ccbde847cc86b016dbdc8e8726a893c 671 Gene3D G3DSA:1.10.12.10 613 669 4.3E-9 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal Tharo_3048 90cb88b95bea3adecd952f17cee87614 765 Gene3D G3DSA:3.40.50.2000 280 736 3.5E-143 T 14-10-2018 Tharo_3048 90cb88b95bea3adecd952f17cee87614 765 Gene3D G3DSA:3.90.1070.10 88 152 6.0E-55 T 14-10-2018 Tharo_3048 90cb88b95bea3adecd952f17cee87614 765 TIGRFAM TIGR02398 gluc_glyc_Psyn: glucosylglycerol-phosphate synthase 257 742 7.9E-227 T 14-10-2018 IPR012764 Glucosylglycerol-phosphate synthase GO:0016758|GO:0051473 MetaCyc: PWY-7902 Tharo_3048 90cb88b95bea3adecd952f17cee87614 765 Gene3D G3DSA:3.40.50.1000 2 230 6.0E-55 T 14-10-2018 IPR023214 HAD superfamily Tharo_3048 90cb88b95bea3adecd952f17cee87614 765 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 2 193 5.0E-15 T 14-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 Tharo_3048 90cb88b95bea3adecd952f17cee87614 765 Gene3D G3DSA:3.40.50.2000 516 725 3.5E-143 T 14-10-2018 Tharo_3048 90cb88b95bea3adecd952f17cee87614 765 Pfam PF00982 Glycosyltransferase family 20 253 739 4.6E-130 T 14-10-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 KEGG: 00500+2.4.1.15 Tharo_3048 90cb88b95bea3adecd952f17cee87614 765 SUPERFAMILY SSF53756 253 738 3.64E-129 T 14-10-2018 Tharo_3048 90cb88b95bea3adecd952f17cee87614 765 Pfam PF05116 Sucrose-6F-phosphate phosphohydrolase 2 233 6.2E-55 T 14-10-2018 IPR006380 Sucrose-phosphatase-like, N-terminal Tharo_3048 90cb88b95bea3adecd952f17cee87614 765 SUPERFAMILY SSF56784 2 205 9.8E-30 T 14-10-2018 IPR036412 HAD-like superfamily Tharo_1097 c0a1a2f3e9ad75526f2252740238d1b0 299 Gene3D G3DSA:3.40.190.290 91 294 6.6E-39 T 14-10-2018 Tharo_1097 c0a1a2f3e9ad75526f2252740238d1b0 299 Gene3D G3DSA:1.10.10.10 1 89 7.0E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1097 c0a1a2f3e9ad75526f2252740238d1b0 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.4E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1097 c0a1a2f3e9ad75526f2252740238d1b0 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.4E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1097 c0a1a2f3e9ad75526f2252740238d1b0 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.4E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1097 c0a1a2f3e9ad75526f2252740238d1b0 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.3E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1097 c0a1a2f3e9ad75526f2252740238d1b0 299 Pfam PF03466 LysR substrate binding domain 87 290 6.4E-35 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_1097 c0a1a2f3e9ad75526f2252740238d1b0 299 SUPERFAMILY SSF53850 89 295 5.55E-36 T 14-10-2018 Tharo_1097 c0a1a2f3e9ad75526f2252740238d1b0 299 SUPERFAMILY SSF46785 1 86 1.67E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1986 16ce470c19ecf6224716f9a47e55d8d3 238 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 97 109 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1986 16ce470c19ecf6224716f9a47e55d8d3 238 Pfam PF13459 4Fe-4S single cluster domain 138 204 2.9E-10 T 14-10-2018 Tharo_1986 16ce470c19ecf6224716f9a47e55d8d3 238 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 82 120 2.7E-13 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1986 16ce470c19ecf6224716f9a47e55d8d3 238 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 32 49 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1986 16ce470c19ecf6224716f9a47e55d8d3 238 PIRSF PIRSF000309 1 229 4.6E-70 T 14-10-2018 IPR016214 NAD-reducing hydrogenase, HoxS gamma subunit MetaCyc: PWY-5382|MetaCyc: PWY-6758 Tharo_1986 16ce470c19ecf6224716f9a47e55d8d3 238 Gene3D G3DSA:3.10.20.740 3 122 4.8E-29 T 14-10-2018 Tharo_1986 16ce470c19ecf6224716f9a47e55d8d3 238 SUPERFAMILY SSF54862 131 205 4.29E-5 T 14-10-2018 Tharo_1986 16ce470c19ecf6224716f9a47e55d8d3 238 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 74 2.0E-15 T 14-10-2018 Tharo_1986 16ce470c19ecf6224716f9a47e55d8d3 238 SUPERFAMILY SSF54292 4 122 1.89E-27 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Tharo_1986 16ce470c19ecf6224716f9a47e55d8d3 238 Gene3D G3DSA:3.30.70.20 127 207 8.9E-8 T 14-10-2018 Tharo_1986 16ce470c19ecf6224716f9a47e55d8d3 238 SMART SM00929 82 122 4.9E-15 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_0575 5b5cd27022e1e312abaaceeda0acbb7e 393 Gene3D G3DSA:1.10.443.10 190 382 4.2E-31 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Tharo_0575 5b5cd27022e1e312abaaceeda0acbb7e 393 Gene3D G3DSA:3.30.160.390 2 82 1.1E-7 T 14-10-2018 IPR038488 Integrase, DNA-binding domain superfamily Tharo_0575 5b5cd27022e1e312abaaceeda0acbb7e 393 Gene3D G3DSA:1.10.150.130 83 189 1.4E-17 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Tharo_0575 5b5cd27022e1e312abaaceeda0acbb7e 393 SUPERFAMILY SSF56349 87 363 1.91E-58 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Tharo_0575 5b5cd27022e1e312abaaceeda0acbb7e 393 Pfam PF00589 Phage integrase family 191 355 5.5E-20 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Tharo_0575 5b5cd27022e1e312abaaceeda0acbb7e 393 Pfam PF13356 Arm DNA-binding domain 17 81 5.8E-13 T 14-10-2018 IPR025166 Integrase, DNA-binding domain Tharo_0790 43f691477368d64e4e6335221b46f64d 355 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 89 99 - T 14-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 Tharo_0790 43f691477368d64e4e6335221b46f64d 355 SUPERFAMILY SSF53774 6 353 1.44E-72 T 14-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 Tharo_0790 43f691477368d64e4e6335221b46f64d 355 SMART SM00870 7 349 2.9E-78 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 Tharo_0790 43f691477368d64e4e6335221b46f64d 355 PIRSF PIRSF500176 265 355 0.12 T 14-10-2018 Tharo_0790 43f691477368d64e4e6335221b46f64d 355 PIRSF PIRSF500176 4 240 1.1E-54 T 14-10-2018 Tharo_0790 43f691477368d64e4e6335221b46f64d 355 PRINTS PR00139 Asparaginase/glutaminase family signature 8 19 1.1E-17 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 Tharo_0790 43f691477368d64e4e6335221b46f64d 355 PRINTS PR00139 Asparaginase/glutaminase family signature 88 106 1.1E-17 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 Tharo_0790 43f691477368d64e4e6335221b46f64d 355 PRINTS PR00139 Asparaginase/glutaminase family signature 292 310 1.1E-17 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 Tharo_0790 43f691477368d64e4e6335221b46f64d 355 Gene3D G3DSA:3.40.50.40 266 354 1.7E-13 T 14-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 Tharo_0790 43f691477368d64e4e6335221b46f64d 355 Pfam PF00710 Asparaginase, N-terminal 7 186 1.4E-52 T 14-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 Tharo_0790 43f691477368d64e4e6335221b46f64d 355 PIRSF PIRSF001220 2 240 1.2E-60 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 Tharo_0790 43f691477368d64e4e6335221b46f64d 355 PIRSF PIRSF001220 266 355 0.18 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 Tharo_0790 43f691477368d64e4e6335221b46f64d 355 Gene3D G3DSA:3.40.50.1170 3 196 9.9E-69 T 14-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 Tharo_0790 43f691477368d64e4e6335221b46f64d 355 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 10 18 - T 14-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 Tharo_0415 eb87a1d3b7a1465f61c585a126d72f9f 366 Pfam PF04892 VanZ like family 26 127 9.5E-11 T 14-10-2018 IPR006976 VanZ-like Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 389 405 5.9E-36 T 14-10-2018 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 418 440 5.9E-36 T 14-10-2018 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 126 145 5.9E-36 T 14-10-2018 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 281 5.9E-36 T 14-10-2018 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 301 319 5.9E-36 T 14-10-2018 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 Gene3D G3DSA:2.40.50.100 6 85 6.5E-22 T 14-10-2018 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 PIRSF PIRSF000350 35 598 2.1E-78 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 31 60 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 124 453 7.2E-56 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 326 4.2E-69 T 14-10-2018 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 563 583 4.2E-69 T 14-10-2018 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 173 4.2E-69 T 14-10-2018 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 433 440 4.2E-69 T 14-10-2018 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 541 556 4.2E-69 T 14-10-2018 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 125 147 4.2E-69 T 14-10-2018 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 476 497 4.2E-69 T 14-10-2018 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 390 404 4.2E-69 T 14-10-2018 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 275 4.2E-69 T 14-10-2018 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 SUPERFAMILY SSF51905 121 463 4.69E-49 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 Pfam PF00364 Biotin-requiring enzyme 9 79 1.2E-20 T 14-10-2018 IPR000089 Biotin/lipoyl attachment Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 159 169 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 123 594 3.1E-145 T 14-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 Gene3D G3DSA:3.50.50.60 278 399 2.6E-119 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 SUPERFAMILY SSF55424 476 599 2.58E-39 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 Gene3D G3DSA:3.50.50.60 124 458 2.6E-119 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 SUPERFAMILY SSF51230 5 100 4.83E-23 T 14-10-2018 IPR011053 Single hybrid motif Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 Gene3D G3DSA:3.30.390.30 479 600 1.0E-46 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Tharo_2630 7e656090cc5549ecf71dd392029b84c1 605 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 480 587 2.7E-36 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Tharo_2401 9133fffb81241e67003b27762b31f7b4 238 Pfam PF01926 50S ribosome-binding GTPase 26 144 1.7E-18 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_2401 9133fffb81241e67003b27762b31f7b4 238 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 191 2.5E-68 T 14-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 Tharo_2401 9133fffb81241e67003b27762b31f7b4 238 SUPERFAMILY SSF52540 25 194 1.42E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2401 9133fffb81241e67003b27762b31f7b4 238 Gene3D G3DSA:3.40.50.300 3 197 3.9E-51 T 14-10-2018 Tharo_2401 9133fffb81241e67003b27762b31f7b4 238 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 12 195 25.943 T 14-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 Tharo_1920 73ade7057570ab6f7840c2399d346f36 779 Gene3D G3DSA:3.40.50.740 273 351 1.8E-14 T 14-10-2018 Tharo_1920 73ade7057570ab6f7840c2399d346f36 779 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1920 73ade7057570ab6f7840c2399d346f36 779 Gene3D G3DSA:3.30.70.20 125 204 8.8E-7 T 14-10-2018 Tharo_1920 73ade7057570ab6f7840c2399d346f36 779 Gene3D G3DSA:3.40.50.740 456 663 1.1E-18 T 14-10-2018 Tharo_1920 73ade7057570ab6f7840c2399d346f36 779 SUPERFAMILY SSF53706 213 655 6.94E-88 T 14-10-2018 Tharo_1920 73ade7057570ab6f7840c2399d346f36 779 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 632 4.4E-198 T 14-10-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1920 73ade7057570ab6f7840c2399d346f36 779 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 145 155 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1920 73ade7057570ab6f7840c2399d346f36 779 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 2 76 6.7E-20 T 14-10-2018 Tharo_1920 73ade7057570ab6f7840c2399d346f36 779 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 83 121 1.1E-16 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1920 73ade7057570ab6f7840c2399d346f36 779 Pfam PF00384 Molybdopterin oxidoreductase 272 438 1.7E-18 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1920 73ade7057570ab6f7840c2399d346f36 779 Pfam PF00384 Molybdopterin oxidoreductase 524 632 1.7E-10 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1920 73ade7057570ab6f7840c2399d346f36 779 Gene3D G3DSA:3.10.20.740 1 124 5.1E-42 T 14-10-2018 Tharo_1920 73ade7057570ab6f7840c2399d346f36 779 SUPERFAMILY SSF54862 75 210 1.21E-36 T 14-10-2018 Tharo_1920 73ade7057570ab6f7840c2399d346f36 779 SUPERFAMILY SSF54292 1 74 5.18E-20 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Tharo_1920 73ade7057570ab6f7840c2399d346f36 779 SMART SM00929 83 123 1.2E-20 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1920 73ade7057570ab6f7840c2399d346f36 779 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 98 110 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_3108 b30e5f658b742d548bc82bc632ca5986 93 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 9 60 1.5E-9 T 14-10-2018 Tharo_3108 b30e5f658b742d548bc82bc632ca5986 93 SUPERFAMILY SSF143120 6 75 1.23E-14 T 14-10-2018 IPR036165 YefM-like superfamily Tharo_3108 b30e5f658b742d548bc82bc632ca5986 93 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 6 72 5.4E-15 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Tharo_3108 b30e5f658b742d548bc82bc632ca5986 93 Gene3D G3DSA:3.40.1620.10 5 43 5.6E-6 T 14-10-2018 Tharo_3016 c64ce9ef51bcacc9c98f9858d9b6718c 128 Gene3D G3DSA:2.30.110.10 4 128 2.7E-36 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 Tharo_3016 c64ce9ef51bcacc9c98f9858d9b6718c 128 SUPERFAMILY SSF50475 9 124 5.7E-24 T 14-10-2018 Tharo_3016 c64ce9ef51bcacc9c98f9858d9b6718c 128 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 100 1.8E-6 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 Tharo_0558 f653baa408076e9dd20ae21cbbbad9b8 83 SUPERFAMILY SSF54862 4 75 1.54E-19 T 14-10-2018 Tharo_0558 f653baa408076e9dd20ae21cbbbad9b8 83 Gene3D G3DSA:3.30.70.20 2 83 7.9E-34 T 14-10-2018 Tharo_0558 f653baa408076e9dd20ae21cbbbad9b8 83 Pfam PF00037 4Fe-4S binding domain 6 24 4.3E-6 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_0558 f653baa408076e9dd20ae21cbbbad9b8 83 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_1299 445ed725453f024f78ab25d263d5653b 179 Pfam PF02915 Rubrerythrin 17 155 7.0E-18 T 14-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 Tharo_1299 445ed725453f024f78ab25d263d5653b 179 SUPERFAMILY SSF47240 13 162 1.18E-33 T 14-10-2018 IPR009078 Ferritin-like superfamily Tharo_1299 445ed725453f024f78ab25d263d5653b 179 Gene3D G3DSA:1.20.1260.10 10 162 2.8E-52 T 14-10-2018 IPR012347 Ferritin-like Tharo_2831 035ae92151dc085bdaa92a338ac5c0e3 815 Pfam PF08447 PAS fold 277 362 4.1E-17 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 Tharo_2831 035ae92151dc085bdaa92a338ac5c0e3 815 Pfam PF00990 Diguanylate cyclase, GGDEF domain 381 535 1.5E-38 T 14-10-2018 IPR000160 GGDEF domain Tharo_2831 035ae92151dc085bdaa92a338ac5c0e3 815 SMART SM00091 253 321 2.1E-7 T 14-10-2018 IPR000014 PAS domain Tharo_2831 035ae92151dc085bdaa92a338ac5c0e3 815 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 379 541 8.0E-33 T 14-10-2018 IPR000160 GGDEF domain Tharo_2831 035ae92151dc085bdaa92a338ac5c0e3 815 Gene3D G3DSA:1.20.1480.50 151 245 3.6E-6 T 14-10-2018 Tharo_2831 035ae92151dc085bdaa92a338ac5c0e3 815 Pfam PF00672 HAMP domain 190 236 1.2E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_2831 035ae92151dc085bdaa92a338ac5c0e3 815 SUPERFAMILY SSF141868 559 803 1.11E-81 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_2831 035ae92151dc085bdaa92a338ac5c0e3 815 Gene3D G3DSA:2.10.70.100 324 370 1.9E-11 T 14-10-2018 Tharo_2831 035ae92151dc085bdaa92a338ac5c0e3 815 Gene3D G3DSA:3.30.70.270 371 545 3.6E-44 T 14-10-2018 Tharo_2831 035ae92151dc085bdaa92a338ac5c0e3 815 Pfam PF00563 EAL domain 559 796 1.9E-73 T 14-10-2018 IPR001633 EAL domain Tharo_2831 035ae92151dc085bdaa92a338ac5c0e3 815 SMART SM00052 553 801 5.7E-103 T 14-10-2018 IPR001633 EAL domain Tharo_2831 035ae92151dc085bdaa92a338ac5c0e3 815 SMART SM00304 187 239 5.2E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_2831 035ae92151dc085bdaa92a338ac5c0e3 815 SUPERFAMILY SSF55785 238 367 3.7E-22 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_2831 035ae92151dc085bdaa92a338ac5c0e3 815 SMART SM00267 370 543 3.2E-49 T 14-10-2018 IPR000160 GGDEF domain Tharo_2831 035ae92151dc085bdaa92a338ac5c0e3 815 Gene3D G3DSA:3.30.450.20 249 322 1.9E-20 T 14-10-2018 Tharo_2831 035ae92151dc085bdaa92a338ac5c0e3 815 SMART SM00086 328 370 1.5E-5 T 14-10-2018 IPR001610 PAC motif Tharo_2831 035ae92151dc085bdaa92a338ac5c0e3 815 Gene3D G3DSA:3.20.20.450 554 811 3.4E-93 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_2831 035ae92151dc085bdaa92a338ac5c0e3 815 SUPERFAMILY SSF55073 386 544 5.18E-37 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_2831 035ae92151dc085bdaa92a338ac5c0e3 815 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 249 377 9.1E-12 T 14-10-2018 IPR000014 PAS domain Tharo_2831 035ae92151dc085bdaa92a338ac5c0e3 815 SUPERFAMILY SSF158472 188 237 2.48E-7 T 14-10-2018 Tharo_1461 973e8fdc4e0c996fd42327b5c9cafe6e 333 SUPERFAMILY SSF51395 2 315 3.85E-64 T 14-10-2018 Tharo_1461 973e8fdc4e0c996fd42327b5c9cafe6e 333 Gene3D G3DSA:3.20.20.70 1 240 7.5E-74 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_1461 973e8fdc4e0c996fd42327b5c9cafe6e 333 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 92 110 - T 14-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 Tharo_1461 973e8fdc4e0c996fd42327b5c9cafe6e 333 Hamap MF_02043 tRNA-dihydrouridine(16) synthase [dusC]. 8 317 48.827 T 14-10-2018 IPR032886 tRNA-dihydrouridine(16) synthase GO:0002943|GO:0017150 Tharo_1461 973e8fdc4e0c996fd42327b5c9cafe6e 333 Pfam PF01207 Dihydrouridine synthase (Dus) 5 286 1.5E-63 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 Tharo_1461 973e8fdc4e0c996fd42327b5c9cafe6e 333 Gene3D G3DSA:1.20.225.30 251 317 4.6E-9 T 14-10-2018 Tharo_1461 973e8fdc4e0c996fd42327b5c9cafe6e 333 PIRSF PIRSF006621 1 324 8.7E-72 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 Tharo_3250 777c361a0ca7d5ce0377c5563f001977 447 Gene3D G3DSA:2.40.30.10 212 308 4.0E-10 T 14-10-2018 Tharo_3250 777c361a0ca7d5ce0377c5563f001977 447 SUPERFAMILY SSF52343 300 442 8.25E-20 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_3250 777c361a0ca7d5ce0377c5563f001977 447 SUPERFAMILY SSF63380 219 310 1.12E-14 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Tharo_3250 777c361a0ca7d5ce0377c5563f001977 447 Pfam PF08022 FAD-binding domain 247 308 3.6E-5 T 14-10-2018 IPR013112 FAD-binding 8 GO:0016491|GO:0055114 Tharo_3250 777c361a0ca7d5ce0377c5563f001977 447 Gene3D G3DSA:3.40.50.80 317 447 3.4E-19 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_3250 777c361a0ca7d5ce0377c5563f001977 447 Pfam PF00175 Oxidoreductase NAD-binding domain 324 425 2.4E-5 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 Tharo_3250 777c361a0ca7d5ce0377c5563f001977 447 Pfam PF01794 Ferric reductase like transmembrane component 45 172 3.1E-20 T 14-10-2018 IPR013130 Ferric reductase transmembrane component-like domain Tharo_3250 777c361a0ca7d5ce0377c5563f001977 447 PRINTS PR00406 Cytochrome B5 reductase signature 412 420 3.3E-6 T 14-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 Tharo_3250 777c361a0ca7d5ce0377c5563f001977 447 PRINTS PR00406 Cytochrome B5 reductase signature 298 312 3.3E-6 T 14-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 Tharo_3250 777c361a0ca7d5ce0377c5563f001977 447 PRINTS PR00406 Cytochrome B5 reductase signature 322 341 3.3E-6 T 14-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 Pfam PF00072 Response regulator receiver domain 1871 1984 2.0E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 Gene3D G3DSA:1.20.120.160 2023 2128 2.9E-6 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 Gene3D G3DSA:3.40.50.12740 1869 2003 4.3E-35 T 14-10-2018 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 Gene3D G3DSA:3.30.450.20 1481 1593 1.4E-20 T 14-10-2018 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 Gene3D G3DSA:3.40.50.300 293 499 3.9E-6 T 14-10-2018 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1775 1789 2.4E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1810 1828 2.4E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1834 1847 2.4E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1793 1803 2.4E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 Pfam PF00069 Protein kinase domain 11 264 1.6E-20 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 SUPERFAMILY SSF52172 1868 1985 1.42E-31 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 Pfam PF01627 Hpt domain 2049 2124 1.0E-5 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 SMART SM00388 1617 1682 6.4E-24 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1729 1846 3.5E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 Gene3D G3DSA:3.30.450.40 1303 1480 1.5E-34 T 14-10-2018 IPR029016 GAF-like domain superfamily Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 1478 1602 8.1E-18 T 14-10-2018 IPR000014 PAS domain Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 Pfam PF00989 PAS fold 1484 1595 2.2E-10 T 14-10-2018 IPR013767 PAS fold GO:0006355 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 SUPERFAMILY SSF55785 1476 1596 3.14E-19 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 SMART SM00091 1482 1550 3.3E-6 T 14-10-2018 IPR000014 PAS domain Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 SUPERFAMILY SSF52540 297 576 2.78E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 Gene3D G3DSA:1.10.287.130 1594 1680 2.3E-28 T 14-10-2018 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 SUPERFAMILY SSF47384 1607 1683 2.75E-21 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 Gene3D G3DSA:3.30.565.10 1681 1849 3.7E-50 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 SUPERFAMILY SSF56112 6 268 6.55E-41 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 SMART SM00387 1729 1850 8.5E-37 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 SUPERFAMILY SSF55874 1671 1846 6.68E-44 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 SMART SM00448 1869 1984 7.6E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 Pfam PF01590 GAF domain 1326 1468 1.5E-16 T 14-10-2018 IPR003018 GAF domain GO:0005515 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 Pfam PF13191 AAA ATPase domain 298 485 3.4E-34 T 14-10-2018 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 SMART SM00065 1325 1478 2.5E-15 T 14-10-2018 IPR003018 GAF domain GO:0005515 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 Gene3D G3DSA:1.10.510.10 90 276 2.6E-34 T 14-10-2018 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 SUPERFAMILY SSF55781 1312 1489 3.49E-27 T 14-10-2018 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1617 1682 2.5E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1279 93c77454145286bd601e8ceda4a861c5 2135 SUPERFAMILY SSF47226 2030 2123 1.7E-9 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 Tharo_1608 30d97d16911aad622f45bfa5dffb059b 195 Pfam PF08281 Sigma-70, region 4 129 178 1.1E-17 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Tharo_1608 30d97d16911aad622f45bfa5dffb059b 195 Pfam PF04542 Sigma-70 region 2 21 88 1.7E-18 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Tharo_1608 30d97d16911aad622f45bfa5dffb059b 195 Gene3D G3DSA:1.10.1740.10 1 118 1.3E-40 T 14-10-2018 Tharo_1608 30d97d16911aad622f45bfa5dffb059b 195 SUPERFAMILY SSF88946 3 106 1.38E-30 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Tharo_1608 30d97d16911aad622f45bfa5dffb059b 195 Gene3D G3DSA:1.10.10.10 119 188 4.8E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1608 30d97d16911aad622f45bfa5dffb059b 195 SUPERFAMILY SSF88659 121 183 2.24E-18 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Tharo_1608 30d97d16911aad622f45bfa5dffb059b 195 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 43 74 - T 14-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Tharo_1608 30d97d16911aad622f45bfa5dffb059b 195 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 2 187 1.9E-103 T 14-10-2018 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Tharo_1608 30d97d16911aad622f45bfa5dffb059b 195 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 183 7.3E-31 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Tharo_1881 88da14059c25af21cba2346ec5014391 282 SUPERFAMILY SSF103088 160 278 7.32E-35 T 14-10-2018 IPR036737 OmpA-like domain superfamily Tharo_1881 88da14059c25af21cba2346ec5014391 282 PRINTS PR01022 Outer membrane protein A signature 157 172 1.4E-6 T 14-10-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 Tharo_1881 88da14059c25af21cba2346ec5014391 282 PRINTS PR01022 Outer membrane protein A signature 257 270 1.4E-6 T 14-10-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 Tharo_1881 88da14059c25af21cba2346ec5014391 282 PRINTS PR01022 Outer membrane protein A signature 223 242 1.4E-6 T 14-10-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 Tharo_1881 88da14059c25af21cba2346ec5014391 282 Pfam PF00691 OmpA family 168 259 3.0E-22 T 14-10-2018 IPR006665 OmpA-like domain Tharo_1881 88da14059c25af21cba2346ec5014391 282 PRINTS PR01021 OMPA domain signature 214 230 4.4E-20 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Tharo_1881 88da14059c25af21cba2346ec5014391 282 PRINTS PR01021 OMPA domain signature 169 191 4.4E-20 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Tharo_1881 88da14059c25af21cba2346ec5014391 282 PRINTS PR01021 OMPA domain signature 199 214 4.4E-20 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Tharo_1881 88da14059c25af21cba2346ec5014391 282 Gene3D G3DSA:3.30.1330.60 144 282 5.5E-50 T 14-10-2018 IPR036737 OmpA-like domain superfamily Tharo_1881 88da14059c25af21cba2346ec5014391 282 ProSitePatterns PS01068 OmpA-like domain. 201 245 - T 14-10-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 Tharo_2698 2dde6f77a3d7003889691d7941436dd0 132 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 26.659 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2698 2dde6f77a3d7003889691d7941436dd0 132 Pfam PF01196 Ribosomal protein L17 20 115 1.6E-34 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2698 2dde6f77a3d7003889691d7941436dd0 132 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 1.1E-45 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2698 2dde6f77a3d7003889691d7941436dd0 132 SUPERFAMILY SSF64263 1 119 2.09E-50 T 14-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2698 2dde6f77a3d7003889691d7941436dd0 132 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2698 2dde6f77a3d7003889691d7941436dd0 132 Gene3D G3DSA:3.90.1030.10 1 116 6.4E-48 T 14-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_0345 a9ce2bd33812c323cbc69797b2050df1 165 PRINTS PR00956 Flagellar motor switch protein FliN signature 83 99 3.0E-28 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 Tharo_0345 a9ce2bd33812c323cbc69797b2050df1 165 PRINTS PR00956 Flagellar motor switch protein FliN signature 116 129 3.0E-28 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 Tharo_0345 a9ce2bd33812c323cbc69797b2050df1 165 PRINTS PR00956 Flagellar motor switch protein FliN signature 129 144 3.0E-28 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 Tharo_0345 a9ce2bd33812c323cbc69797b2050df1 165 PRINTS PR00956 Flagellar motor switch protein FliN signature 100 116 3.0E-28 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 Tharo_0345 a9ce2bd33812c323cbc69797b2050df1 165 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 81 155 1.4E-32 T 14-10-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 Tharo_0345 a9ce2bd33812c323cbc69797b2050df1 165 Gene3D G3DSA:2.30.330.10 71 164 8.1E-35 T 14-10-2018 IPR036429 SpoA-like superfamily Tharo_0345 a9ce2bd33812c323cbc69797b2050df1 165 SUPERFAMILY SSF101801 80 162 9.81E-26 T 14-10-2018 IPR036429 SpoA-like superfamily Tharo_0345 a9ce2bd33812c323cbc69797b2050df1 165 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 83 153 6.4E-25 T 14-10-2018 IPR001543 Surface presentation of antigen (SpoA) Tharo_1432 443049cdf32056fd6b4d860698f14ef4 551 Gene3D G3DSA:1.20.1250.20 322 549 4.4E-63 T 14-10-2018 Tharo_1432 443049cdf32056fd6b4d860698f14ef4 551 Gene3D G3DSA:1.20.1250.20 8 252 5.2E-74 T 14-10-2018 Tharo_1432 443049cdf32056fd6b4d860698f14ef4 551 SUPERFAMILY SSF103473 21 319 4.19E-12 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_1432 443049cdf32056fd6b4d860698f14ef4 551 SUPERFAMILY SSF103473 302 543 3.66E-17 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_1432 443049cdf32056fd6b4d860698f14ef4 551 Pfam PF07690 Major Facilitator Superfamily 346 546 1.3E-9 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_3399 cc7d0c2419484fce7fede7c3e0549ea2 640 Pfam PF12161 HsdM N-terminal domain 129 245 2.1E-24 T 14-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain Tharo_3399 cc7d0c2419484fce7fede7c3e0549ea2 640 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 398 404 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Tharo_3399 cc7d0c2419484fce7fede7c3e0549ea2 640 Gene3D G3DSA:3.40.50.150 268 583 1.5E-116 T 14-10-2018 Tharo_3399 cc7d0c2419484fce7fede7c3e0549ea2 640 SUPERFAMILY SSF53335 129 639 5.03E-137 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_3399 cc7d0c2419484fce7fede7c3e0549ea2 640 Gene3D G3DSA:1.20.1260.30 125 258 4.3E-43 T 14-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily Tharo_3399 cc7d0c2419484fce7fede7c3e0549ea2 640 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 429 453 1.4E-19 T 14-10-2018 Tharo_3399 cc7d0c2419484fce7fede7c3e0549ea2 640 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 395 407 1.4E-19 T 14-10-2018 Tharo_3399 cc7d0c2419484fce7fede7c3e0549ea2 640 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 321 335 1.4E-19 T 14-10-2018 Tharo_3399 cc7d0c2419484fce7fede7c3e0549ea2 640 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 291 307 1.4E-19 T 14-10-2018 Tharo_3399 cc7d0c2419484fce7fede7c3e0549ea2 640 Pfam PF02384 N-6 DNA Methylase 267 600 3.1E-110 T 14-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 Tharo_2598 c854b104edb9bafbd2ed03a7fa1269e1 375 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 76 134 1.3E-4 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Tharo_2598 c854b104edb9bafbd2ed03a7fa1269e1 375 SUPERFAMILY SSF51735 163 339 1.61E-34 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_2598 c854b104edb9bafbd2ed03a7fa1269e1 375 Gene3D G3DSA:3.90.180.10 65 372 6.2E-117 T 14-10-2018 Tharo_2598 c854b104edb9bafbd2ed03a7fa1269e1 375 Gene3D G3DSA:3.40.50.720 173 341 6.2E-117 T 14-10-2018 Tharo_2598 c854b104edb9bafbd2ed03a7fa1269e1 375 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 49 373 3.1E-136 T 14-10-2018 IPR014188 Acrylyl-CoA reductase AcuI Tharo_2598 c854b104edb9bafbd2ed03a7fa1269e1 375 Pfam PF00107 Zinc-binding dehydrogenase 206 319 9.6E-9 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Tharo_2598 c854b104edb9bafbd2ed03a7fa1269e1 375 SUPERFAMILY SSF50129 48 190 5.17E-41 T 14-10-2018 IPR011032 GroES-like superfamily Tharo_2598 c854b104edb9bafbd2ed03a7fa1269e1 375 SMART SM00829 63 371 8.1E-6 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Tharo_0582 7152a20156c1bef8142a8ed58c6d8854 297 Pfam PF13362 Toprim domain 194 288 3.0E-11 T 14-10-2018 IPR006171 TOPRIM domain Tharo_1253 7106c50290e79ff54ffa0a9b0543822f 316 Gene3D G3DSA:3.40.190.10 96 293 5.8E-62 T 14-10-2018 Tharo_1253 7106c50290e79ff54ffa0a9b0543822f 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 4.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1253 7106c50290e79ff54ffa0a9b0543822f 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 4.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1253 7106c50290e79ff54ffa0a9b0543822f 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 4.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1253 7106c50290e79ff54ffa0a9b0543822f 316 SUPERFAMILY SSF46785 3 79 1.63E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1253 7106c50290e79ff54ffa0a9b0543822f 316 Pfam PF03466 LysR substrate binding domain 91 296 4.3E-23 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_1253 7106c50290e79ff54ffa0a9b0543822f 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 9.5E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1253 7106c50290e79ff54ffa0a9b0543822f 316 Gene3D G3DSA:1.10.10.10 1 84 1.5E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1253 7106c50290e79ff54ffa0a9b0543822f 316 Gene3D G3DSA:3.40.190.10 170 269 5.8E-62 T 14-10-2018 Tharo_1253 7106c50290e79ff54ffa0a9b0543822f 316 SUPERFAMILY SSF53850 88 297 7.39E-42 T 14-10-2018 Tharo_1824 79a0c0c8e153ba3ff5dadab9c7f4247c 456 SMART SM00382 160 303 4.2E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1824 79a0c0c8e153ba3ff5dadab9c7f4247c 456 SUPERFAMILY SSF52172 4 183 6.69E-41 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1824 79a0c0c8e153ba3ff5dadab9c7f4247c 456 Gene3D G3DSA:3.40.50.300 131 310 1.4E-61 T 14-10-2018 Tharo_1824 79a0c0c8e153ba3ff5dadab9c7f4247c 456 Gene3D G3DSA:1.10.8.60 311 390 4.8E-23 T 14-10-2018 Tharo_1824 79a0c0c8e153ba3ff5dadab9c7f4247c 456 Pfam PF02954 Bacterial regulatory protein, Fis family 414 454 1.2E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_1824 79a0c0c8e153ba3ff5dadab9c7f4247c 456 Pfam PF00158 Sigma-54 interaction domain 140 306 2.6E-62 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Tharo_1824 79a0c0c8e153ba3ff5dadab9c7f4247c 456 Gene3D G3DSA:1.10.10.60 394 456 1.1E-11 T 14-10-2018 Tharo_1824 79a0c0c8e153ba3ff5dadab9c7f4247c 456 Pfam PF00072 Response regulator receiver domain 4 113 6.4E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1824 79a0c0c8e153ba3ff5dadab9c7f4247c 456 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 226 241 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Tharo_1824 79a0c0c8e153ba3ff5dadab9c7f4247c 456 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 437 456 5.8E-11 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_1824 79a0c0c8e153ba3ff5dadab9c7f4247c 456 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 420 437 5.8E-11 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_1824 79a0c0c8e153ba3ff5dadab9c7f4247c 456 Gene3D G3DSA:3.40.50.2300 2 130 1.6E-36 T 14-10-2018 Tharo_1824 79a0c0c8e153ba3ff5dadab9c7f4247c 456 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 353 362 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Tharo_1824 79a0c0c8e153ba3ff5dadab9c7f4247c 456 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 164 177 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Tharo_1824 79a0c0c8e153ba3ff5dadab9c7f4247c 456 SUPERFAMILY SSF52540 138 383 2.62E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1824 79a0c0c8e153ba3ff5dadab9c7f4247c 456 SUPERFAMILY SSF46689 353 456 6.27E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_1824 79a0c0c8e153ba3ff5dadab9c7f4247c 456 SMART SM00448 2 113 1.4E-34 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1281 0ba5ab268d3a73e3b3d57a536541e18c 530 Gene3D G3DSA:2.60.40.10 391 522 9.6E-40 T 14-10-2018 IPR013783 Immunoglobulin-like fold Tharo_1281 0ba5ab268d3a73e3b3d57a536541e18c 530 Pfam PF09100 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV 396 527 2.8E-44 T 14-10-2018 IPR015184 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV Tharo_1281 0ba5ab268d3a73e3b3d57a536541e18c 530 Pfam PF09098 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding 32 195 2.7E-61 T 14-10-2018 IPR015182 Quinohemoprotein amine dehydrogenase, alpha subunit, haem binding domain Tharo_1281 0ba5ab268d3a73e3b3d57a536541e18c 530 Gene3D G3DSA:2.40.128.120 201 311 8.7E-32 T 14-10-2018 IPR036718 Quinohemoprotein amine dehydrogenase alpha subunit, domain 2 superfamily Tharo_1281 0ba5ab268d3a73e3b3d57a536541e18c 530 Gene3D G3DSA:1.10.760.10 29 95 8.1E-7 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_1281 0ba5ab268d3a73e3b3d57a536541e18c 530 Pfam PF09099 Quinohemoprotein amine dehydrogenase, alpha subunit domain III 313 391 9.6E-21 T 14-10-2018 IPR015183 Quinohemoprotein amine dehydrogenase, alpha subunit domain III Tharo_1281 0ba5ab268d3a73e3b3d57a536541e18c 530 SUPERFAMILY SSF81296 392 529 1.12E-43 T 14-10-2018 IPR014756 Immunoglobulin E-set Tharo_1281 0ba5ab268d3a73e3b3d57a536541e18c 530 Gene3D G3DSA:2.60.40.10 313 390 4.5E-22 T 14-10-2018 IPR013783 Immunoglobulin-like fold Tharo_1281 0ba5ab268d3a73e3b3d57a536541e18c 530 Pfam PF14930 Quinohemoprotein amine dehydrogenase, alpha subunit domain II 205 308 9.2E-35 T 14-10-2018 IPR009111 Quinohemoprotein amine dehydrogenase, alpha subunit, domain 2 Tharo_1281 0ba5ab268d3a73e3b3d57a536541e18c 530 SUPERFAMILY SSF69298 191 308 6.8E-36 T 14-10-2018 IPR036718 Quinohemoprotein amine dehydrogenase alpha subunit, domain 2 superfamily Tharo_1281 0ba5ab268d3a73e3b3d57a536541e18c 530 SUPERFAMILY SSF81296 312 391 1.33E-16 T 14-10-2018 IPR014756 Immunoglobulin E-set Tharo_1281 0ba5ab268d3a73e3b3d57a536541e18c 530 SUPERFAMILY SSF46626 115 192 1.22E-24 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_1281 0ba5ab268d3a73e3b3d57a536541e18c 530 SUPERFAMILY SSF46626 32 111 5.05E-13 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_1281 0ba5ab268d3a73e3b3d57a536541e18c 530 TIGRFAM TIGR03908 QH_alpha: quinohemoprotein amine dehydrogenase, alpha subunit 27 525 4.5E-177 T 14-10-2018 IPR023887 Quinohemoprotein amine dehydrogenase, alpha subunit Tharo_2724 e9933dd6d704198b3793ecabc5f7602d 212 Pfam PF00297 Ribosomal protein L3 101 185 3.7E-16 T 14-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2724 e9933dd6d704198b3793ecabc5f7602d 212 Gene3D G3DSA:2.40.30.10 134 212 2.7E-14 T 14-10-2018 Tharo_2724 e9933dd6d704198b3793ecabc5f7602d 212 ProSitePatterns PS00474 Ribosomal protein L3 signature. 104 127 - T 14-10-2018 IPR019926 Ribosomal protein L3, conserved site Tharo_2724 e9933dd6d704198b3793ecabc5f7602d 212 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 207 1.1E-84 T 14-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2724 e9933dd6d704198b3793ecabc5f7602d 212 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 210 39.217 T 14-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2724 e9933dd6d704198b3793ecabc5f7602d 212 Gene3D G3DSA:2.40.50.620 33 95 1.3E-16 T 14-10-2018 Tharo_2724 e9933dd6d704198b3793ecabc5f7602d 212 SUPERFAMILY SSF50447 2 211 2.38E-78 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Tharo_2424 6929f515ac377d14987911b88edb625e 1073 SUPERFAMILY SSF82714 203 284 1.1E-17 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_2424 6929f515ac377d14987911b88edb625e 1073 Pfam PF00873 AcrB/AcrD/AcrF family 34 1053 6.0E-233 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_2424 6929f515ac377d14987911b88edb625e 1073 Gene3D G3DSA:1.20.1640.10 34 527 3.5E-261 T 14-10-2018 Tharo_2424 6929f515ac377d14987911b88edb625e 1073 SUPERFAMILY SSF82714 734 819 6.54E-13 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_2424 6929f515ac377d14987911b88edb625e 1073 SUPERFAMILY SSF82693 66 148 2.3E-20 T 14-10-2018 Tharo_2424 6929f515ac377d14987911b88edb625e 1073 SUPERFAMILY SSF82693 157 345 1.49E-19 T 14-10-2018 Tharo_2424 6929f515ac377d14987911b88edb625e 1073 SUPERFAMILY SSF82866 818 1056 5.23E-49 T 14-10-2018 Tharo_2424 6929f515ac377d14987911b88edb625e 1073 Gene3D G3DSA:3.30.70.1440 682 879 3.5E-261 T 14-10-2018 Tharo_2424 6929f515ac377d14987911b88edb625e 1073 Gene3D G3DSA:1.20.1640.10 528 1049 3.5E-261 T 14-10-2018 Tharo_2424 6929f515ac377d14987911b88edb625e 1073 Gene3D G3DSA:3.30.70.1430 62 829 3.5E-261 T 14-10-2018 Tharo_2424 6929f515ac377d14987911b88edb625e 1073 SUPERFAMILY SSF82866 311 517 1.44E-39 T 14-10-2018 Tharo_2424 6929f515ac377d14987911b88edb625e 1073 Gene3D G3DSA:3.30.2090.10 199 289 3.5E-261 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_2424 6929f515ac377d14987911b88edb625e 1073 Gene3D G3DSA:3.30.70.1320 155 347 3.5E-261 T 14-10-2018 Tharo_2424 6929f515ac377d14987911b88edb625e 1073 Gene3D G3DSA:3.30.2090.10 733 821 3.5E-261 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_2424 6929f515ac377d14987911b88edb625e 1073 Gene3D G3DSA:3.30.70.1430 579 681 3.5E-261 T 14-10-2018 Tharo_2424 6929f515ac377d14987911b88edb625e 1073 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 22 1054 0.0 T 14-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 Tharo_2424 6929f515ac377d14987911b88edb625e 1073 PRINTS PR00702 Acriflavin resistance protein family signature 406 430 9.4E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_2424 6929f515ac377d14987911b88edb625e 1073 PRINTS PR00702 Acriflavin resistance protein family signature 351 374 9.4E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_2424 6929f515ac377d14987911b88edb625e 1073 PRINTS PR00702 Acriflavin resistance protein family signature 490 513 9.4E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_2424 6929f515ac377d14987911b88edb625e 1073 PRINTS PR00702 Acriflavin resistance protein family signature 378 399 9.4E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_2424 6929f515ac377d14987911b88edb625e 1073 PRINTS PR00702 Acriflavin resistance protein family signature 60 78 9.4E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_2424 6929f515ac377d14987911b88edb625e 1073 PRINTS PR00702 Acriflavin resistance protein family signature 32 56 9.4E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_2696 98bef987217ff03ce6f3d637c804de77 961 ProSitePatterns PS00211 ABC transporters family signature. 828 842 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_2696 98bef987217ff03ce6f3d637c804de77 961 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 938 22.359 T 14-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 Tharo_2696 98bef987217ff03ce6f3d637c804de77 961 Gene3D G3DSA:1.20.1580.10 90 491 2.0E-242 T 14-10-2018 Tharo_2696 98bef987217ff03ce6f3d637c804de77 961 Gene3D G3DSA:1.10.8.280 286 402 2.0E-242 T 14-10-2018 Tharo_2696 98bef987217ff03ce6f3d637c804de77 961 SUPERFAMILY SSF52540 612 908 2.71E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2696 98bef987217ff03ce6f3d637c804de77 961 SMART SM00382 631 938 0.0077 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2696 98bef987217ff03ce6f3d637c804de77 961 Gene3D G3DSA:1.20.1580.10 691 828 1.3E-140 T 14-10-2018 Tharo_2696 98bef987217ff03ce6f3d637c804de77 961 ProSitePatterns PS00211 ABC transporters family signature. 486 500 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_2696 98bef987217ff03ce6f3d637c804de77 961 Gene3D G3DSA:3.40.50.300 612 934 1.3E-140 T 14-10-2018 Tharo_2696 98bef987217ff03ce6f3d637c804de77 961 Gene3D G3DSA:3.30.190.20 131 243 2.0E-242 T 14-10-2018 Tharo_2696 98bef987217ff03ce6f3d637c804de77 961 Gene3D G3DSA:3.40.50.300 6 594 2.0E-242 T 14-10-2018 Tharo_2696 98bef987217ff03ce6f3d637c804de77 961 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 4 923 0.0 T 14-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 Tharo_2696 98bef987217ff03ce6f3d637c804de77 961 SUPERFAMILY SSF52540 3 568 1.56E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0027 45eab2128d1f8916761ef11fab8c00ea 364 Pfam PF13515 Fusaric acid resistance protein-like 211 336 1.1E-24 T 14-10-2018 Tharo_1292 64565b48e349a20505d3bc6d8cd67f59 416 Gene3D G3DSA:3.40.50.920 276 415 9.5E-36 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Tharo_1292 64565b48e349a20505d3bc6d8cd67f59 416 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 33 230 8.0E-51 T 14-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 Tharo_1292 64565b48e349a20505d3bc6d8cd67f59 416 SUPERFAMILY SSF52922 277 397 3.28E-28 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Tharo_1292 64565b48e349a20505d3bc6d8cd67f59 416 SUPERFAMILY SSF52518 20 273 2.06E-56 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_1292 64565b48e349a20505d3bc6d8cd67f59 416 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 286 387 2.0E-23 T 14-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II Tharo_1292 64565b48e349a20505d3bc6d8cd67f59 416 Gene3D G3DSA:3.40.50.970 18 275 1.6E-83 T 14-10-2018 Tharo_1351 dba4abf7080464a25f18a8749831f0f4 491 Gene3D G3DSA:3.30.300.20 200 278 1.3E-29 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta Tharo_1351 dba4abf7080464a25f18a8749831f0f4 491 Gene3D G3DSA:1.10.150.20 430 488 3.0E-21 T 14-10-2018 Tharo_1351 dba4abf7080464a25f18a8749831f0f4 491 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 343 5.3E-121 T 14-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 Tharo_1351 dba4abf7080464a25f18a8749831f0f4 491 Pfam PF13184 NusA-like KH domain 231 298 2.2E-25 T 14-10-2018 IPR025249 KH domain, NusA-like GO:0003723 Tharo_1351 dba4abf7080464a25f18a8749831f0f4 491 SUPERFAMILY SSF47794 356 417 2.35E-16 T 14-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 Tharo_1351 dba4abf7080464a25f18a8749831f0f4 491 SUPERFAMILY SSF69705 1 128 1.96E-38 T 14-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 Tharo_1351 dba4abf7080464a25f18a8749831f0f4 491 Pfam PF00575 S1 RNA binding domain 140 196 1.4E-4 T 14-10-2018 IPR003029 S1 domain GO:0003676 Tharo_1351 dba4abf7080464a25f18a8749831f0f4 491 Pfam PF08529 NusA N-terminal domain 4 126 4.8E-36 T 14-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 Tharo_1351 dba4abf7080464a25f18a8749831f0f4 491 Gene3D G3DSA:2.40.50.140 139 199 2.9E-20 T 14-10-2018 Tharo_1351 dba4abf7080464a25f18a8749831f0f4 491 SUPERFAMILY SSF54814 201 278 2.68E-28 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Tharo_1351 dba4abf7080464a25f18a8749831f0f4 491 Gene3D G3DSA:1.10.150.20 354 422 7.7E-28 T 14-10-2018 Tharo_1351 dba4abf7080464a25f18a8749831f0f4 491 SMART SM00316 135 201 1.1E-6 T 14-10-2018 IPR022967 RNA-binding domain, S1 Tharo_1351 dba4abf7080464a25f18a8749831f0f4 491 SUPERFAMILY SSF47794 428 489 2.67E-14 T 14-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 Tharo_1351 dba4abf7080464a25f18a8749831f0f4 491 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 411 29.014 T 14-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 Tharo_1351 dba4abf7080464a25f18a8749831f0f4 491 Gene3D G3DSA:3.30.300.20 279 348 9.6E-25 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta Tharo_1351 dba4abf7080464a25f18a8749831f0f4 491 Gene3D G3DSA:3.30.1480.10 1 131 9.5E-40 T 14-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 Tharo_1351 dba4abf7080464a25f18a8749831f0f4 491 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 439 488 1.6E-15 T 14-10-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication Tharo_1351 dba4abf7080464a25f18a8749831f0f4 491 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 366 414 3.8E-20 T 14-10-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication Tharo_1351 dba4abf7080464a25f18a8749831f0f4 491 SUPERFAMILY SSF54814 280 343 3.4E-15 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Tharo_1351 dba4abf7080464a25f18a8749831f0f4 491 Pfam PF14520 Helix-hairpin-helix domain 431 485 1.9E-9 T 14-10-2018 Tharo_1351 dba4abf7080464a25f18a8749831f0f4 491 SUPERFAMILY SSF50249 136 200 6.21E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_2169 558fb4efa8b24d428d7e9d0509a966a0 684 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 315 7.2E-21 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Tharo_2169 558fb4efa8b24d428d7e9d0509a966a0 684 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 574 659 7.8E-15 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Tharo_2169 558fb4efa8b24d428d7e9d0509a966a0 684 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 296 5.6E-16 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Tharo_2169 558fb4efa8b24d428d7e9d0509a966a0 684 Gene3D G3DSA:3.40.50.300 2 322 7.3E-89 T 14-10-2018 Tharo_2169 558fb4efa8b24d428d7e9d0509a966a0 684 Gene3D G3DSA:3.40.50.300 341 684 4.5E-97 T 14-10-2018 Tharo_2169 558fb4efa8b24d428d7e9d0509a966a0 684 Pfam PF00005 ABC transporter 371 523 1.4E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_2169 558fb4efa8b24d428d7e9d0509a966a0 684 SMART SM00382 379 572 6.2E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2169 558fb4efa8b24d428d7e9d0509a966a0 684 SMART SM00382 32 230 8.9E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2169 558fb4efa8b24d428d7e9d0509a966a0 684 SUPERFAMILY SSF52540 343 594 1.25E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2169 558fb4efa8b24d428d7e9d0509a966a0 684 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_2169 558fb4efa8b24d428d7e9d0509a966a0 684 ProSitePatterns PS00211 ABC transporters family signature. 495 509 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_2169 558fb4efa8b24d428d7e9d0509a966a0 684 SUPERFAMILY SSF52540 33 306 2.48E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2169 558fb4efa8b24d428d7e9d0509a966a0 684 Pfam PF00005 ABC transporter 24 180 1.6E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_0533 ca1ca6cb180c703005be174d07181997 303 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 11 245 5.8E-43 T 14-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 Tharo_0533 ca1ca6cb180c703005be174d07181997 303 Gene3D G3DSA:3.40.50.620 8 292 2.0E-103 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_0533 ca1ca6cb180c703005be174d07181997 303 Gene3D G3DSA:3.40.50.620 83 226 2.0E-103 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_0533 ca1ca6cb180c703005be174d07181997 303 SUPERFAMILY SSF52374 8 293 7.11E-85 T 14-10-2018 Tharo_0533 ca1ca6cb180c703005be174d07181997 303 PRINTS PR00987 Glutamyl-tRNA synthetase signature 11 23 2.3E-12 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Tharo_0533 ca1ca6cb180c703005be174d07181997 303 PRINTS PR00987 Glutamyl-tRNA synthetase signature 178 188 2.3E-12 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Tharo_0533 ca1ca6cb180c703005be174d07181997 303 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 202 2.3E-12 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Tharo_0533 ca1ca6cb180c703005be174d07181997 303 PRINTS PR00987 Glutamyl-tRNA synthetase signature 40 53 2.3E-12 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Tharo_0533 ca1ca6cb180c703005be174d07181997 303 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 8 298 44.428 T 14-10-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0004812|GO:0006400 Tharo_0533 ca1ca6cb180c703005be174d07181997 303 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 8 278 2.1E-115 T 14-10-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0004812|GO:0006400 Tharo_0049 8242eae53c8dfb421ef33ec9ffc144a8 185 PIRSF PIRSF005901 1 185 8.1E-59 T 14-10-2018 IPR020599 Translation elongation factor P/YeiP Tharo_0049 8242eae53c8dfb421ef33ec9ffc144a8 185 TIGRFAM TIGR00038 efp: translation elongation factor P 3 184 4.9E-66 T 14-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 Tharo_0049 8242eae53c8dfb421ef33ec9ffc144a8 185 SUPERFAMILY SSF50249 65 125 2.87E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_0049 8242eae53c8dfb421ef33ec9ffc144a8 185 SMART SM00841 128 183 1.5E-27 T 14-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 Tharo_0049 8242eae53c8dfb421ef33ec9ffc144a8 185 SMART SM01185 67 120 3.0E-20 T 14-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 Tharo_0049 8242eae53c8dfb421ef33ec9ffc144a8 185 SUPERFAMILY SSF50249 128 184 1.88E-17 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_0049 8242eae53c8dfb421ef33ec9ffc144a8 185 Gene3D G3DSA:2.40.50.140 127 185 2.7E-27 T 14-10-2018 Tharo_0049 8242eae53c8dfb421ef33ec9ffc144a8 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 2.0E-19 T 14-10-2018 IPR013185 Translation elongation factor, KOW-like Tharo_0049 8242eae53c8dfb421ef33ec9ffc144a8 185 Pfam PF09285 Elongation factor P, C-terminal 128 183 9.0E-24 T 14-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 Tharo_0049 8242eae53c8dfb421ef33ec9ffc144a8 185 Gene3D G3DSA:2.30.30.30 1 62 3.0E-19 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 Tharo_0049 8242eae53c8dfb421ef33ec9ffc144a8 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 120 7.9E-18 T 14-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 Tharo_0049 8242eae53c8dfb421ef33ec9ffc144a8 185 ProSitePatterns PS01275 Elongation factor P signature. 149 168 - T 14-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site Tharo_0049 8242eae53c8dfb421ef33ec9ffc144a8 185 SUPERFAMILY SSF50104 1 63 4.96E-17 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily Tharo_0049 8242eae53c8dfb421ef33ec9ffc144a8 185 Gene3D G3DSA:2.40.50.140 64 125 4.3E-22 T 14-10-2018 Tharo_0049 8242eae53c8dfb421ef33ec9ffc144a8 185 Hamap MF_00141 Elongation factor P [efp]. 1 184 47.87 T 14-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 Tharo_2611 da2f602d2e97e527bec5416b1f6ec291 1714 Pfam PF00270 DEAD/DEAH box helicase 309 477 1.8E-15 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Tharo_2611 da2f602d2e97e527bec5416b1f6ec291 1714 Pfam PF13245 AAA domain 1105 1283 2.2E-32 T 14-10-2018 Tharo_2611 da2f602d2e97e527bec5416b1f6ec291 1714 SUPERFAMILY SSF52540 1095 1576 3.15E-77 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2611 da2f602d2e97e527bec5416b1f6ec291 1714 SMART SM00479 11 149 0.0016 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Tharo_2611 da2f602d2e97e527bec5416b1f6ec291 1714 SUPERFAMILY SSF53098 10 161 3.11E-9 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_2611 da2f602d2e97e527bec5416b1f6ec291 1714 Gene3D G3DSA:3.40.50.300 1500 1593 2.7E-13 T 14-10-2018 Tharo_2611 da2f602d2e97e527bec5416b1f6ec291 1714 SUPERFAMILY SSF52540 349 645 5.22E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2611 da2f602d2e97e527bec5416b1f6ec291 1714 Gene3D G3DSA:1.10.486.10 1438 1459 4.1E-8 T 14-10-2018 Tharo_2611 da2f602d2e97e527bec5416b1f6ec291 1714 Gene3D G3DSA:3.40.50.300 502 702 2.2E-43 T 14-10-2018 Tharo_2611 da2f602d2e97e527bec5416b1f6ec291 1714 Gene3D G3DSA:3.40.50.300 1308 1434 4.1E-8 T 14-10-2018 Tharo_2611 da2f602d2e97e527bec5416b1f6ec291 1714 Gene3D G3DSA:3.40.50.300 280 493 1.7E-54 T 14-10-2018 Tharo_2611 da2f602d2e97e527bec5416b1f6ec291 1714 Pfam PF00271 Helicase conserved C-terminal domain 518 626 1.9E-16 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_2611 da2f602d2e97e527bec5416b1f6ec291 1714 SMART SM00490 547 628 1.9E-23 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_2611 da2f602d2e97e527bec5416b1f6ec291 1714 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 291 645 1.7E-81 T 14-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 Tharo_2611 da2f602d2e97e527bec5416b1f6ec291 1714 Gene3D G3DSA:3.30.420.10 12 141 1.9E-11 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_2611 da2f602d2e97e527bec5416b1f6ec291 1714 SMART SM00487 301 510 5.1E-17 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Tharo_2611 da2f602d2e97e527bec5416b1f6ec291 1714 Pfam PF13538 UvrD-like helicase C-terminal domain 1523 1572 2.7E-12 T 14-10-2018 IPR027785 UvrD-like helicase C-terminal domain Tharo_2611 da2f602d2e97e527bec5416b1f6ec291 1714 Gene3D G3DSA:3.40.50.300 1093 1305 1.8E-47 T 14-10-2018 Tharo_0942 715a14ce617344f3c5cad8b7f9aabebe 1122 SUPERFAMILY SSF53756 395 737 6.28E-35 T 14-10-2018 Tharo_0942 715a14ce617344f3c5cad8b7f9aabebe 1122 Pfam PF00534 Glycosyl transferases group 1 176 335 2.3E-27 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 Tharo_0942 715a14ce617344f3c5cad8b7f9aabebe 1122 Pfam PF00534 Glycosyl transferases group 1 544 672 1.3E-12 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 Tharo_0942 715a14ce617344f3c5cad8b7f9aabebe 1122 Gene3D G3DSA:3.40.50.2000 918 1104 6.9E-14 T 14-10-2018 Tharo_0942 715a14ce617344f3c5cad8b7f9aabebe 1122 SUPERFAMILY SSF53756 754 1115 7.33E-22 T 14-10-2018 Tharo_0942 715a14ce617344f3c5cad8b7f9aabebe 1122 SUPERFAMILY SSF53756 11 357 2.28E-48 T 14-10-2018 Tharo_0942 715a14ce617344f3c5cad8b7f9aabebe 1122 Gene3D G3DSA:3.40.50.2000 171 337 5.8E-37 T 14-10-2018 Tharo_0942 715a14ce617344f3c5cad8b7f9aabebe 1122 Gene3D G3DSA:3.40.50.2000 529 742 5.5E-34 T 14-10-2018 Tharo_0815 a0bcb0ea709bd3f3f192ddd00bfd7687 498 SUPERFAMILY SSF143968 334 498 4.18E-68 T 14-10-2018 Tharo_0815 a0bcb0ea709bd3f3f192ddd00bfd7687 498 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 11 442 1.1E-168 T 14-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 Tharo_0815 a0bcb0ea709bd3f3f192ddd00bfd7687 498 Gene3D G3DSA:1.20.5.570 466 498 1.4E-11 T 14-10-2018 Tharo_0815 a0bcb0ea709bd3f3f192ddd00bfd7687 498 Gene3D G3DSA:3.40.1670.10 348 465 6.2E-51 T 14-10-2018 Tharo_0815 a0bcb0ea709bd3f3f192ddd00bfd7687 498 Hamap MF_01636 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [ubiD]. 1 498 71.098 T 14-10-2018 IPR023677 UbiD decarboxylyase, bacteria GO:0005886|GO:0006744|GO:0008694 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 Tharo_0815 a0bcb0ea709bd3f3f192ddd00bfd7687 498 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 466 2.7E-169 T 14-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 Tharo_0815 a0bcb0ea709bd3f3f192ddd00bfd7687 498 SUPERFAMILY SSF50475 3 333 4.71E-119 T 14-10-2018 Tharo_2370 5184d931136d7076c3e42ca1c46ab726 357 SUPERFAMILY SSF51569 7 348 1.05E-135 T 14-10-2018 Tharo_2370 5184d931136d7076c3e42ca1c46ab726 357 Pfam PF00793 DAHP synthetase I family 39 337 2.1E-105 T 14-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 Tharo_2370 5184d931136d7076c3e42ca1c46ab726 357 PIRSF PIRSF001361 1 352 2.4E-160 T 14-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 Tharo_2370 5184d931136d7076c3e42ca1c46ab726 357 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 6 349 1.6E-165 T 14-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 Tharo_2370 5184d931136d7076c3e42ca1c46ab726 357 Gene3D G3DSA:3.20.20.70 1 350 3.1E-161 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_2900 b4ce880b82af2e1823b1192d9d61a7f2 182 Pfam PF07456 Heptaprenyl diphosphate synthase component I 22 166 1.7E-43 T 14-10-2018 IPR010898 Heptaprenyl diphosphate synthase component I Tharo_2900 b4ce880b82af2e1823b1192d9d61a7f2 182 Gene3D G3DSA:1.10.1760.20 16 174 6.6E-10 T 14-10-2018 Tharo_2900 b4ce880b82af2e1823b1192d9d61a7f2 182 PIRSF PIRSF027391 11 177 4.3E-30 T 14-10-2018 IPR014535 Predicted heptaprenyl diphosphate synthase, component I Tharo_1227 171e0cc90475893b5961c30b28f2a7ad 796 Pfam PF03484 tRNA synthetase B5 domain 406 471 5.9E-18 T 14-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 Tharo_1227 171e0cc90475893b5961c30b28f2a7ad 796 Gene3D G3DSA:3.30.930.10 489 688 4.7E-54 T 14-10-2018 Tharo_1227 171e0cc90475893b5961c30b28f2a7ad 796 Pfam PF03147 Ferredoxin-fold anticodon binding domain 699 792 1.2E-25 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 Tharo_1227 171e0cc90475893b5961c30b28f2a7ad 796 Gene3D G3DSA:3.30.56.10 4 181 4.3E-73 T 14-10-2018 Tharo_1227 171e0cc90475893b5961c30b28f2a7ad 796 SUPERFAMILY SSF50249 38 192 2.94E-51 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_1227 171e0cc90475893b5961c30b28f2a7ad 796 SUPERFAMILY SSF46955 405 475 5.49E-18 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily Tharo_1227 171e0cc90475893b5961c30b28f2a7ad 796 SMART SM00896 699 792 9.3E-37 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 Tharo_1227 171e0cc90475893b5961c30b28f2a7ad 796 Gene3D G3DSA:3.50.40.10 198 394 2.2E-72 T 14-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 Tharo_1227 171e0cc90475893b5961c30b28f2a7ad 796 SUPERFAMILY SSF55681 467 686 1.09E-45 T 14-10-2018 Tharo_1227 171e0cc90475893b5961c30b28f2a7ad 796 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 786 43.362 T 14-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 Tharo_1227 171e0cc90475893b5961c30b28f2a7ad 796 Gene3D G3DSA:2.40.50.140 39 154 4.3E-73 T 14-10-2018 Tharo_1227 171e0cc90475893b5961c30b28f2a7ad 796 Pfam PF01588 Putative tRNA binding domain 45 145 1.0E-24 T 14-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 Tharo_1227 171e0cc90475893b5961c30b28f2a7ad 796 SMART SM00874 403 471 3.9E-26 T 14-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 Tharo_1227 171e0cc90475893b5961c30b28f2a7ad 796 Gene3D G3DSA:3.30.56.10 404 476 3.4E-24 T 14-10-2018 Tharo_1227 171e0cc90475893b5961c30b28f2a7ad 796 Pfam PF03483 B3/4 domain 212 385 1.9E-68 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 Tharo_1227 171e0cc90475893b5961c30b28f2a7ad 796 Gene3D G3DSA:3.30.70.380 700 792 6.6E-26 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 Tharo_1227 171e0cc90475893b5961c30b28f2a7ad 796 SUPERFAMILY SSF56037 197 391 9.94E-69 T 14-10-2018 Tharo_1227 171e0cc90475893b5961c30b28f2a7ad 796 SMART SM00873 212 385 2.4E-90 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 Tharo_1227 171e0cc90475893b5961c30b28f2a7ad 796 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 792 1.2E-235 T 14-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 Tharo_1227 171e0cc90475893b5961c30b28f2a7ad 796 SUPERFAMILY SSF54991 694 792 1.2E-26 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 1 517 4.6E-242 T 14-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 Gene3D G3DSA:3.50.50.60 328 450 9.9E-111 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 Gene3D G3DSA:3.50.50.60 217 508 9.9E-111 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 346 366 - T 14-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 Pfam PF13192 Thioredoxin domain 129 198 3.6E-7 T 14-10-2018 IPR012336 Thioredoxin-like fold Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 Gene3D G3DSA:3.40.30.80 1 204 5.9E-64 T 14-10-2018 Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 PIRSF PIRSF000238 1 521 4.4E-261 T 14-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 218 240 2.1E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 354 378 2.1E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 406 422 2.1E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 317 325 2.1E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 250 265 2.1E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 339 351 2.1E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 270 280 2.1E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 444 465 2.1E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 478 496 2.1E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 SUPERFAMILY SSF52833 1 106 3.35E-28 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 468 490 1.4E-40 T 14-10-2018 Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 442 458 1.4E-40 T 14-10-2018 Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 316 334 1.4E-40 T 14-10-2018 Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 358 376 1.4E-40 T 14-10-2018 Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 219 238 1.4E-40 T 14-10-2018 Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 SUPERFAMILY SSF52833 108 201 7.47E-23 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 217 504 7.2E-49 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Tharo_0567 a57fc93b24bea20f4509fc0605fd3c2b 522 SUPERFAMILY SSF51905 207 514 4.01E-52 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_2405 6457a8c15896d89b10c9509e83fa887a 235 SUPERFAMILY SSF109755 7 221 2.3E-63 T 14-10-2018 Tharo_2405 6457a8c15896d89b10c9509e83fa887a 235 Pfam PF01895 PhoU domain 127 208 2.1E-14 T 14-10-2018 IPR026022 PhoU domain Tharo_2405 6457a8c15896d89b10c9509e83fa887a 235 Pfam PF01895 PhoU domain 21 107 1.0E-16 T 14-10-2018 IPR026022 PhoU domain Tharo_2405 6457a8c15896d89b10c9509e83fa887a 235 Gene3D G3DSA:1.20.58.220 1 117 5.5E-33 T 14-10-2018 IPR038078 PhoU-like domain superfamily Tharo_2405 6457a8c15896d89b10c9509e83fa887a 235 PIRSF PIRSF003107 2 223 2.5E-61 T 14-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 Tharo_2405 6457a8c15896d89b10c9509e83fa887a 235 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 7 218 1.0E-64 T 14-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 Tharo_2405 6457a8c15896d89b10c9509e83fa887a 235 Gene3D G3DSA:1.20.58.220 118 232 9.4E-31 T 14-10-2018 IPR038078 PhoU-like domain superfamily Tharo_0107 7d16764e7c88d4e87cda04b2d0f9a735 256 PIRSF PIRSF009320 87 255 1.1E-9 T 14-10-2018 Tharo_0107 7d16764e7c88d4e87cda04b2d0f9a735 256 PIRSF PIRSF009320 2 51 6.3E-15 T 14-10-2018 Tharo_0107 7d16764e7c88d4e87cda04b2d0f9a735 256 SUPERFAMILY SSF52540 1 253 3.86E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0107 7d16764e7c88d4e87cda04b2d0f9a735 256 Gene3D G3DSA:3.40.50.300 1 255 1.5E-77 T 14-10-2018 Tharo_0107 7d16764e7c88d4e87cda04b2d0f9a735 256 Pfam PF13614 AAA domain 3 178 9.0E-62 T 14-10-2018 IPR025669 AAA domain Tharo_3211 ec6d5553b59becee9fabda0a034ba91c 386 Gene3D G3DSA:3.30.2110.10 24 203 3.6E-43 T 14-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 Tharo_3211 ec6d5553b59becee9fabda0a034ba91c 386 SUPERFAMILY SSF111342 18 305 4.58E-75 T 14-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 Tharo_3211 ec6d5553b59becee9fabda0a034ba91c 386 Pfam PF01888 CbiD 23 289 2.3E-83 T 14-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 Tharo_3211 ec6d5553b59becee9fabda0a034ba91c 386 PIRSF PIRSF026782 18 385 2.5E-98 T 14-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 Tharo_3211 ec6d5553b59becee9fabda0a034ba91c 386 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 22 381 26.113 T 14-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 Tharo_3211 ec6d5553b59becee9fabda0a034ba91c 386 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 31 375 3.4E-61 T 14-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 Tharo_1554 e5b35e63b8b3b4eea10ea213a91f7b4e 121 Pfam PF00545 ribonuclease 35 115 2.0E-27 T 14-10-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 Tharo_1554 e5b35e63b8b3b4eea10ea213a91f7b4e 121 Gene3D G3DSA:3.10.450.30 28 119 3.4E-36 T 14-10-2018 Tharo_1554 e5b35e63b8b3b4eea10ea213a91f7b4e 121 SUPERFAMILY SSF53933 33 119 7.94E-34 T 14-10-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 Tharo_1852 87b08c3d6f7724095624341539432d77 445 SMART SM00387 330 442 1.6E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1852 87b08c3d6f7724095624341539432d77 445 SUPERFAMILY SSF47384 204 287 7.46E-16 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_1852 87b08c3d6f7724095624341539432d77 445 SMART SM00388 221 287 5.8E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1852 87b08c3d6f7724095624341539432d77 445 Gene3D G3DSA:3.30.565.10 296 441 9.6E-25 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1852 87b08c3d6f7724095624341539432d77 445 SUPERFAMILY SSF55874 276 433 2.75E-26 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1852 87b08c3d6f7724095624341539432d77 445 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 4 438 2.0E-104 T 14-10-2018 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 Tharo_1852 87b08c3d6f7724095624341539432d77 445 Pfam PF00512 His Kinase A (phospho-acceptor) domain 222 287 1.1E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1852 87b08c3d6f7724095624341539432d77 445 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 331 434 3.8E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1852 87b08c3d6f7724095624341539432d77 445 Gene3D G3DSA:1.10.287.130 171 288 8.4E-19 T 14-10-2018 Tharo_1852 87b08c3d6f7724095624341539432d77 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 421 6.9E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1852 87b08c3d6f7724095624341539432d77 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 396 6.9E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1852 87b08c3d6f7724095624341539432d77 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 382 6.9E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1684 82d2efaa63a9c215e6bb114b77af8e9d 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 111 130 7.3E-7 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Tharo_1684 82d2efaa63a9c215e6bb114b77af8e9d 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 51 58 7.3E-7 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Tharo_1684 82d2efaa63a9c215e6bb114b77af8e9d 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 136 145 7.3E-7 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Tharo_1684 82d2efaa63a9c215e6bb114b77af8e9d 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 215 223 7.3E-7 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Tharo_1684 82d2efaa63a9c215e6bb114b77af8e9d 258 Pfam PF00175 Oxidoreductase NAD-binding domain 112 229 2.9E-9 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 Tharo_1684 82d2efaa63a9c215e6bb114b77af8e9d 258 Pfam PF00970 Oxidoreductase FAD-binding domain 15 98 7.0E-8 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 Tharo_1684 82d2efaa63a9c215e6bb114b77af8e9d 258 SUPERFAMILY SSF52343 103 256 5.76E-42 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_1684 82d2efaa63a9c215e6bb114b77af8e9d 258 Gene3D G3DSA:3.40.50.80 100 254 1.0E-42 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_1684 82d2efaa63a9c215e6bb114b77af8e9d 258 SUPERFAMILY SSF63380 4 99 8.6E-26 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Tharo_1684 82d2efaa63a9c215e6bb114b77af8e9d 258 Gene3D G3DSA:2.40.30.10 1 97 2.3E-29 T 14-10-2018 Tharo_0490 ffa8e82726ab11237965de03ec696d7b 480 SUPERFAMILY SSF161093 308 479 2.22E-48 T 14-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 Tharo_0490 ffa8e82726ab11237965de03ec696d7b 480 Gene3D G3DSA:1.10.357.20 305 479 3.7E-46 T 14-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain Tharo_0490 ffa8e82726ab11237965de03ec696d7b 480 SUPERFAMILY SSF158791 43 163 4.71E-28 T 14-10-2018 Tharo_0490 ffa8e82726ab11237965de03ec696d7b 480 Pfam PF01769 Divalent cation transporter 351 472 3.9E-25 T 14-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 Tharo_0490 ffa8e82726ab11237965de03ec696d7b 480 Gene3D G3DSA:1.25.60.10 37 161 2.0E-18 T 14-10-2018 IPR038076 MgtE, N-terminal domain superfamily Tharo_0490 ffa8e82726ab11237965de03ec696d7b 480 Pfam PF00571 CBS domain 166 222 4.0E-6 T 14-10-2018 IPR000644 CBS domain Tharo_0490 ffa8e82726ab11237965de03ec696d7b 480 Pfam PF00571 CBS domain 230 285 1.6E-7 T 14-10-2018 IPR000644 CBS domain Tharo_0490 ffa8e82726ab11237965de03ec696d7b 480 TIGRFAM TIGR00400 mgtE: magnesium transporter 40 479 1.9E-88 T 14-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 Tharo_0490 ffa8e82726ab11237965de03ec696d7b 480 SMART SM00116 173 226 0.46 T 14-10-2018 IPR000644 CBS domain Tharo_0490 ffa8e82726ab11237965de03ec696d7b 480 SMART SM00116 238 286 1.1E-4 T 14-10-2018 IPR000644 CBS domain Tharo_0490 ffa8e82726ab11237965de03ec696d7b 480 Pfam PF03448 MgtE intracellular N domain 63 164 2.3E-25 T 14-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain Tharo_0490 ffa8e82726ab11237965de03ec696d7b 480 Gene3D G3DSA:3.10.580.10 162 290 7.4E-41 T 14-10-2018 Tharo_0490 ffa8e82726ab11237965de03ec696d7b 480 SUPERFAMILY SSF54631 165 305 1.05E-28 T 14-10-2018 Tharo_0490 ffa8e82726ab11237965de03ec696d7b 480 SMART SM00924 63 166 6.4E-36 T 14-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain Tharo_2158 8b6dffc4011606cf6433ce49f5e67e4d 61 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 19 56 2.5E-9 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 Tharo_2158 8b6dffc4011606cf6433ce49f5e67e4d 61 Gene3D G3DSA:1.10.150.130 16 60 2.6E-12 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Tharo_1925 e28cd6535422f42add07510d7b48b3e2 673 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 7 668 8.3E-246 T 14-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1925 e28cd6535422f42add07510d7b48b3e2 673 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 86 106 6.5E-16 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 Tharo_1925 e28cd6535422f42add07510d7b48b3e2 673 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 489 510 6.5E-16 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 Tharo_1925 e28cd6535422f42add07510d7b48b3e2 673 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 426 448 6.5E-16 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 Tharo_1925 e28cd6535422f42add07510d7b48b3e2 673 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 36 55 6.5E-16 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 Tharo_1925 e28cd6535422f42add07510d7b48b3e2 673 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 272 294 6.5E-16 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 Tharo_1925 e28cd6535422f42add07510d7b48b3e2 673 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 427 446 3.3E-66 T 14-10-2018 Tharo_1925 e28cd6535422f42add07510d7b48b3e2 673 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 159 180 3.3E-66 T 14-10-2018 Tharo_1925 e28cd6535422f42add07510d7b48b3e2 673 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 322 334 3.3E-66 T 14-10-2018 Tharo_1925 e28cd6535422f42add07510d7b48b3e2 673 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 232 253 3.3E-66 T 14-10-2018 Tharo_1925 e28cd6535422f42add07510d7b48b3e2 673 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 3.3E-66 T 14-10-2018 Tharo_1925 e28cd6535422f42add07510d7b48b3e2 673 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 254 280 3.3E-66 T 14-10-2018 Tharo_1925 e28cd6535422f42add07510d7b48b3e2 673 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 84 109 3.3E-66 T 14-10-2018 Tharo_1925 e28cd6535422f42add07510d7b48b3e2 673 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 66 123 1.9E-26 T 14-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1925 e28cd6535422f42add07510d7b48b3e2 673 Pfam PF00361 Proton-conducting membrane transporter 135 415 1.7E-86 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_2042 9b1c5d5ce038ed35f82aa76d16259cc6 622 SUPERFAMILY SSF52540 143 307 2.22E-6 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2042 9b1c5d5ce038ed35f82aa76d16259cc6 622 SUPERFAMILY SSF54211 444 616 4.93E-22 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_2042 9b1c5d5ce038ed35f82aa76d16259cc6 622 Gene3D G3DSA:3.30.230.10 439 621 2.2E-16 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Tharo_2042 9b1c5d5ce038ed35f82aa76d16259cc6 622 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 483 621 8.5E-8 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 Tharo_2042 9b1c5d5ce038ed35f82aa76d16259cc6 622 TIGRFAM TIGR02688 TIGR02688: TIGR02688 family protein 2 403 2.2E-120 T 14-10-2018 IPR014061 Conserved hypothetical protein CHP02688 Tharo_2042 9b1c5d5ce038ed35f82aa76d16259cc6 622 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 552 571 1.1E-7 T 14-10-2018 Tharo_2042 9b1c5d5ce038ed35f82aa76d16259cc6 622 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 169 188 1.1E-7 T 14-10-2018 Tharo_2042 9b1c5d5ce038ed35f82aa76d16259cc6 622 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 575 593 1.1E-7 T 14-10-2018 Tharo_2042 9b1c5d5ce038ed35f82aa76d16259cc6 622 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 522 541 1.1E-7 T 14-10-2018 Tharo_2042 9b1c5d5ce038ed35f82aa76d16259cc6 622 Pfam PF13337 Putative ATP-dependent Lon protease 2 413 9.0E-162 T 14-10-2018 IPR014061 Conserved hypothetical protein CHP02688 Tharo_2190 638a22db003b0adf909325950c14098f 217 Pfam PF05191 Adenylate kinase, active site lid 123 158 2.7E-16 T 14-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 Tharo_2190 638a22db003b0adf909325950c14098f 217 Hamap MF_00235 Adenylate kinase [adk]. 1 217 53.708 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Tharo_2190 638a22db003b0adf909325950c14098f 217 PRINTS PR00094 Adenylate kinase signature 173 187 1.9E-35 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Tharo_2190 638a22db003b0adf909325950c14098f 217 PRINTS PR00094 Adenylate kinase signature 32 46 1.9E-35 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Tharo_2190 638a22db003b0adf909325950c14098f 217 PRINTS PR00094 Adenylate kinase signature 81 97 1.9E-35 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Tharo_2190 638a22db003b0adf909325950c14098f 217 PRINTS PR00094 Adenylate kinase signature 4 17 1.9E-35 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Tharo_2190 638a22db003b0adf909325950c14098f 217 PRINTS PR00094 Adenylate kinase signature 156 171 1.9E-35 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Tharo_2190 638a22db003b0adf909325950c14098f 217 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 14-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Tharo_2190 638a22db003b0adf909325950c14098f 217 TIGRFAM TIGR01351 adk: adenylate kinase 2 187 1.2E-73 T 14-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 Tharo_2190 638a22db003b0adf909325950c14098f 217 Gene3D G3DSA:3.40.50.300 1 216 1.8E-76 T 14-10-2018 Tharo_2190 638a22db003b0adf909325950c14098f 217 SUPERFAMILY SSF52540 1 188 1.96E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2190 638a22db003b0adf909325950c14098f 217 Pfam PF00406 Adenylate kinase 5 185 3.4E-58 T 14-10-2018 Tharo_0806 129329eef5bffc6a325192b0da70c6d2 686 SMART SM00490 498 582 2.7E-19 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_0806 129329eef5bffc6a325192b0da70c6d2 686 SUPERFAMILY SSF52540 205 447 1.75E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0806 129329eef5bffc6a325192b0da70c6d2 686 Gene3D G3DSA:3.40.50.300 203 443 4.0E-80 T 14-10-2018 Tharo_0806 129329eef5bffc6a325192b0da70c6d2 686 Gene3D G3DSA:3.40.50.300 451 623 1.2E-52 T 14-10-2018 Tharo_0806 129329eef5bffc6a325192b0da70c6d2 686 SUPERFAMILY SSF52540 281 644 1.73E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0806 129329eef5bffc6a325192b0da70c6d2 686 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 25 657 1.4E-210 T 14-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 Tharo_0806 129329eef5bffc6a325192b0da70c6d2 686 SMART SM00487 256 453 3.2E-25 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Tharo_0806 129329eef5bffc6a325192b0da70c6d2 686 Gene3D G3DSA:2.40.50.140 42 133 1.4E-6 T 14-10-2018 Tharo_0806 129329eef5bffc6a325192b0da70c6d2 686 Pfam PF17191 RecG wedge domain 10 163 4.2E-13 T 14-10-2018 IPR033454 RecG, wedge domain Tharo_0806 129329eef5bffc6a325192b0da70c6d2 686 Pfam PF00271 Helicase conserved C-terminal domain 475 581 2.0E-16 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_0806 129329eef5bffc6a325192b0da70c6d2 686 Pfam PF00270 DEAD/DEAH box helicase 281 428 6.6E-15 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Tharo_0806 129329eef5bffc6a325192b0da70c6d2 686 SUPERFAMILY SSF50249 9 165 1.11E-30 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_2577 d160123106878e04aed15e12bf88437a 317 Pfam PF12762 ISXO2-like transposase domain 138 283 1.1E-29 T 14-10-2018 IPR024445 ISXO2-like transposase domain Tharo_2577 d160123106878e04aed15e12bf88437a 317 SMART SM01126 137 283 3.8E-39 T 14-10-2018 IPR024445 ISXO2-like transposase domain Tharo_2577 d160123106878e04aed15e12bf88437a 317 Pfam PF12760 Transposase zinc-ribbon domain 23 69 3.4E-13 T 14-10-2018 IPR024442 Transposase, zinc-ribbon Tharo_3017 d160123106878e04aed15e12bf88437a 317 Pfam PF12762 ISXO2-like transposase domain 138 283 1.1E-29 T 14-10-2018 IPR024445 ISXO2-like transposase domain Tharo_3017 d160123106878e04aed15e12bf88437a 317 SMART SM01126 137 283 3.8E-39 T 14-10-2018 IPR024445 ISXO2-like transposase domain Tharo_3017 d160123106878e04aed15e12bf88437a 317 Pfam PF12760 Transposase zinc-ribbon domain 23 69 3.4E-13 T 14-10-2018 IPR024442 Transposase, zinc-ribbon Tharo_0211 d160123106878e04aed15e12bf88437a 317 Pfam PF12762 ISXO2-like transposase domain 138 283 1.1E-29 T 14-10-2018 IPR024445 ISXO2-like transposase domain Tharo_0211 d160123106878e04aed15e12bf88437a 317 SMART SM01126 137 283 3.8E-39 T 14-10-2018 IPR024445 ISXO2-like transposase domain Tharo_0211 d160123106878e04aed15e12bf88437a 317 Pfam PF12760 Transposase zinc-ribbon domain 23 69 3.4E-13 T 14-10-2018 IPR024442 Transposase, zinc-ribbon Tharo_0190 aba8a009a7a18b74bafcf00e85c9912e 343 Gene3D G3DSA:3.20.20.30 1 343 1.1E-86 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 Tharo_0190 aba8a009a7a18b74bafcf00e85c9912e 343 Pfam PF00296 Luciferase-like monooxygenase 2 312 3.4E-64 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Tharo_0190 aba8a009a7a18b74bafcf00e85c9912e 343 SUPERFAMILY SSF51679 1 343 1.7E-82 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 Tharo_0809 31ca73b91e976fafae706f03c1e440b1 290 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 64 86 - T 14-10-2018 IPR030470 UbiA prenyltransferase conserved site Tharo_0809 31ca73b91e976fafae706f03c1e440b1 290 Pfam PF01040 UbiA prenyltransferase family 25 269 4.8E-62 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 Tharo_0809 31ca73b91e976fafae706f03c1e440b1 290 Gene3D G3DSA:1.20.120.1780 168 290 5.0E-10 T 14-10-2018 Tharo_0809 31ca73b91e976fafae706f03c1e440b1 290 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 9 283 1.6E-103 T 14-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 Tharo_0809 31ca73b91e976fafae706f03c1e440b1 290 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 2 285 29.677 T 14-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 Tharo_0809 31ca73b91e976fafae706f03c1e440b1 290 Gene3D G3DSA:1.10.357.140 20 167 4.7E-41 T 14-10-2018 Tharo_1830 10128aedaf5f8d3de81372da0f025297 215 SMART SM00382 27 213 1.0E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1830 10128aedaf5f8d3de81372da0f025297 215 SUPERFAMILY SSF52540 2 212 2.79E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1830 10128aedaf5f8d3de81372da0f025297 215 Gene3D G3DSA:3.40.50.300 1 215 3.7E-53 T 14-10-2018 Tharo_1830 10128aedaf5f8d3de81372da0f025297 215 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_1830 10128aedaf5f8d3de81372da0f025297 215 Pfam PF00005 ABC transporter 18 162 2.4E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_1959 23d2d10ecb501a5a8cac8a38228fa58b 546 Gene3D G3DSA:3.30.420.150 156 335 2.5E-84 T 14-10-2018 Tharo_1959 23d2d10ecb501a5a8cac8a38228fa58b 546 SUPERFAMILY SSF53067 52 173 1.47E-33 T 14-10-2018 Tharo_1959 23d2d10ecb501a5a8cac8a38228fa58b 546 Pfam PF02541 Ppx/GppA phosphatase family 73 347 3.7E-73 T 14-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 Tharo_1959 23d2d10ecb501a5a8cac8a38228fa58b 546 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 52 346 2.6E-97 T 14-10-2018 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 Tharo_1959 23d2d10ecb501a5a8cac8a38228fa58b 546 PIRSF PIRSF001267 43 538 4.7E-196 T 14-10-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 Tharo_1959 23d2d10ecb501a5a8cac8a38228fa58b 546 SUPERFAMILY SSF53067 178 351 4.66E-43 T 14-10-2018 Tharo_1959 23d2d10ecb501a5a8cac8a38228fa58b 546 SUPERFAMILY SSF109604 353 536 6.85E-45 T 14-10-2018 Tharo_1959 23d2d10ecb501a5a8cac8a38228fa58b 546 Gene3D G3DSA:3.30.420.40 53 343 2.5E-84 T 14-10-2018 Tharo_1959 23d2d10ecb501a5a8cac8a38228fa58b 546 Gene3D G3DSA:1.10.3210.10 350 541 1.8E-56 T 14-10-2018 Tharo_2458 4f92df5317f152c26dc496cfe14d07d4 765 SMART SM00919 163 400 1.1E-143 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 Tharo_2458 4f92df5317f152c26dc496cfe14d07d4 765 Gene3D G3DSA:3.40.50.720 161 441 2.0E-85 T 14-10-2018 Tharo_2458 4f92df5317f152c26dc496cfe14d07d4 765 PIRSF PIRSF036684 1 761 0.0 T 14-10-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 Tharo_2458 4f92df5317f152c26dc496cfe14d07d4 765 Pfam PF03949 Malic enzyme, NAD binding domain 165 358 9.3E-21 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 Tharo_2458 4f92df5317f152c26dc496cfe14d07d4 765 Gene3D G3DSA:3.40.50.10750 575 729 1.9E-91 T 14-10-2018 Tharo_2458 4f92df5317f152c26dc496cfe14d07d4 765 Gene3D G3DSA:3.40.50.10380 1 160 7.6E-68 T 14-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 Tharo_2458 4f92df5317f152c26dc496cfe14d07d4 765 SUPERFAMILY SSF51735 163 438 8.04E-87 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_2458 4f92df5317f152c26dc496cfe14d07d4 765 SUPERFAMILY SSF53223 10 161 1.08E-50 T 14-10-2018 Tharo_2458 4f92df5317f152c26dc496cfe14d07d4 765 Pfam PF00390 Malic enzyme, N-terminal domain 19 113 1.5E-19 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 Tharo_2458 4f92df5317f152c26dc496cfe14d07d4 765 Pfam PF00390 Malic enzyme, N-terminal domain 114 151 1.5E-5 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 Tharo_2458 4f92df5317f152c26dc496cfe14d07d4 765 SUPERFAMILY SSF53659 429 756 4.52E-92 T 14-10-2018 Tharo_2458 4f92df5317f152c26dc496cfe14d07d4 765 PRINTS PR00072 Malic enzyme signature 80 102 3.2E-5 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 Tharo_2458 4f92df5317f152c26dc496cfe14d07d4 765 PRINTS PR00072 Malic enzyme signature 190 206 3.2E-5 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 Tharo_2458 4f92df5317f152c26dc496cfe14d07d4 765 PRINTS PR00072 Malic enzyme signature 159 175 3.2E-5 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 Tharo_2458 4f92df5317f152c26dc496cfe14d07d4 765 Pfam PF01515 Phosphate acetyl/butaryl transferase 429 753 3.6E-98 T 14-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 Tharo_2458 4f92df5317f152c26dc496cfe14d07d4 765 SMART SM01274 18 151 3.3E-75 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 Tharo_2458 4f92df5317f152c26dc496cfe14d07d4 765 Gene3D G3DSA:3.40.50.10950 442 756 1.9E-91 T 14-10-2018 Tharo_1138 47e99d63df77c400c45fcee4f1e193b7 532 Gene3D G3DSA:1.10.10.2900 255 325 1.1E-31 T 14-10-2018 Tharo_1138 47e99d63df77c400c45fcee4f1e193b7 532 Pfam PF13193 AMP-binding enzyme C-terminal domain 442 520 2.2E-19 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Tharo_1138 47e99d63df77c400c45fcee4f1e193b7 532 Pfam PF00501 AMP-binding enzyme 39 434 2.2E-84 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Tharo_1138 47e99d63df77c400c45fcee4f1e193b7 532 Gene3D G3DSA:2.30.38.10 326 433 5.9E-36 T 14-10-2018 Tharo_1138 47e99d63df77c400c45fcee4f1e193b7 532 Gene3D G3DSA:3.40.50.980 17 254 6.5E-58 T 14-10-2018 Tharo_1138 47e99d63df77c400c45fcee4f1e193b7 532 SUPERFAMILY SSF56801 17 530 1.31E-142 T 14-10-2018 Tharo_1138 47e99d63df77c400c45fcee4f1e193b7 532 TIGRFAM TIGR02262 benz_CoA_lig: benzoate-CoA ligase family 21 528 6.4E-268 T 14-10-2018 IPR011957 Benzoate-CoA ligase family GO:0005524|GO:0016405 Tharo_1138 47e99d63df77c400c45fcee4f1e193b7 532 Gene3D G3DSA:3.30.300.310 434 531 1.9E-28 T 14-10-2018 Tharo_0644 372f74cd636e89c651fe048829b8e52d 78 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 48 1.7E-23 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 Tharo_0644 372f74cd636e89c651fe048829b8e52d 78 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 66 23.435 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 Tharo_0644 372f74cd636e89c651fe048829b8e52d 78 Pfam PF02416 mttA/Hcf106 family 5 49 4.7E-14 T 14-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 Gene3D G3DSA:3.30.450.20 74 207 8.1E-11 T 14-10-2018 Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 SMART SM00267 448 620 9.1E-66 T 14-10-2018 IPR000160 GGDEF domain Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 SUPERFAMILY SSF55785 207 317 9.07E-22 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 SUPERFAMILY SSF55073 464 622 4.39E-51 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 SUPERFAMILY SSF141868 636 882 3.53E-86 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 456 618 4.5E-43 T 14-10-2018 IPR000160 GGDEF domain Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 Pfam PF00563 EAL domain 638 871 6.2E-70 T 14-10-2018 IPR001633 EAL domain Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 SMART SM00052 630 876 2.3E-110 T 14-10-2018 IPR001633 EAL domain Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 Gene3D G3DSA:3.20.20.450 634 883 1.4E-97 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 SMART SM00086 284 325 34.0 T 14-10-2018 IPR001610 PAC motif Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 SMART SM00086 406 448 3.1E-5 T 14-10-2018 IPR001610 PAC motif Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 207 328 1.2E-16 T 14-10-2018 IPR000014 PAS domain Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 330 455 6.9E-14 T 14-10-2018 IPR000014 PAS domain Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 Gene3D G3DSA:3.30.450.20 208 321 4.9E-19 T 14-10-2018 Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 SUPERFAMILY SSF55785 323 445 5.58E-22 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 SMART SM00091 88 155 24.0 T 14-10-2018 IPR000014 PAS domain Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 SMART SM00091 209 277 8.0E-8 T 14-10-2018 IPR000014 PAS domain Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 SMART SM00091 333 400 0.0072 T 14-10-2018 IPR000014 PAS domain Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 PIRSF PIRSF005925 322 452 3.0E-9 T 14-10-2018 IPR012226 Diguanylate cyclase/phosphodiesterase Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 PIRSF PIRSF005925 208 320 5.2E-7 T 14-10-2018 IPR012226 Diguanylate cyclase/phosphodiesterase Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 PIRSF PIRSF005925 446 884 4.5E-148 T 14-10-2018 IPR012226 Diguanylate cyclase/phosphodiesterase Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 Gene3D G3DSA:3.30.450.20 322 457 1.4E-31 T 14-10-2018 Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 SUPERFAMILY SSF55785 81 202 2.44E-9 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 Pfam PF13426 PAS domain 344 446 5.0E-13 T 14-10-2018 IPR000014 PAS domain Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 Pfam PF00990 Diguanylate cyclase, GGDEF domain 459 615 9.3E-51 T 14-10-2018 IPR000160 GGDEF domain Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 Gene3D G3DSA:3.30.70.270 458 633 7.0E-64 T 14-10-2018 Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 Pfam PF08448 PAS fold 227 314 8.6E-11 T 14-10-2018 IPR013656 PAS fold-4 Tharo_0779 bad9c9476d43a951d3d45eaf6045c1b3 885 Pfam PF08448 PAS fold 95 205 4.8E-7 T 14-10-2018 IPR013656 PAS fold-4 Tharo_2040 86b4f89519f78f1076559a115ad0baff 293 Pfam PF08241 Methyltransferase domain 69 173 1.2E-18 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 Tharo_2040 86b4f89519f78f1076559a115ad0baff 293 Gene3D G3DSA:3.40.50.150 13 293 1.0E-32 T 14-10-2018 Tharo_2040 86b4f89519f78f1076559a115ad0baff 293 SUPERFAMILY SSF53335 25 293 2.81E-37 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_2040 86b4f89519f78f1076559a115ad0baff 293 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 19 292 25.34 T 14-10-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00780+2.1.1.197|MetaCyc: PWY-6519 Tharo_0739 277f762512ed950105dfa1cb190f7b55 548 SUPERFAMILY SSF110849 37 159 6.02E-10 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily Tharo_0739 277f762512ed950105dfa1cb190f7b55 548 TIGRFAM TIGR03764 ICE_PFGI_1_parB: integrating conjugative element, PFGI_1 class, ParB family protein 28 290 6.4E-123 T 14-10-2018 IPR022304 Integrating conjugative element, PFGI-1, ParB Tharo_0739 277f762512ed950105dfa1cb190f7b55 548 Pfam PF02195 ParB-like nuclease domain 39 102 1.3E-4 T 14-10-2018 IPR003115 ParB/Sulfiredoxin Tharo_1397 07ed1752a67d5e1a71ca1aa72511d177 499 Pfam PF01336 OB-fold nucleic acid binding domain 65 142 1.2E-17 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 Tharo_1397 07ed1752a67d5e1a71ca1aa72511d177 499 Gene3D G3DSA:2.40.50.140 12 150 1.0E-42 T 14-10-2018 Tharo_1397 07ed1752a67d5e1a71ca1aa72511d177 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 258 275 2.6E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Tharo_1397 07ed1752a67d5e1a71ca1aa72511d177 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 381 397 2.6E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Tharo_1397 07ed1752a67d5e1a71ca1aa72511d177 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 195 205 2.6E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Tharo_1397 07ed1752a67d5e1a71ca1aa72511d177 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 211 227 2.6E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Tharo_1397 07ed1752a67d5e1a71ca1aa72511d177 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 240 253 2.6E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Tharo_1397 07ed1752a67d5e1a71ca1aa72511d177 499 SUPERFAMILY SSF55681 158 497 4.79E-115 T 14-10-2018 Tharo_1397 07ed1752a67d5e1a71ca1aa72511d177 499 SUPERFAMILY SSF50249 10 151 4.29E-45 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_1397 07ed1752a67d5e1a71ca1aa72511d177 499 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 18 499 44.032 T 14-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Tharo_1397 07ed1752a67d5e1a71ca1aa72511d177 499 Pfam PF00152 tRNA synthetases class II (D, K and N) 159 496 1.0E-82 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_1397 07ed1752a67d5e1a71ca1aa72511d177 499 Gene3D G3DSA:3.30.930.10 154 499 1.6E-127 T 14-10-2018 Tharo_1397 07ed1752a67d5e1a71ca1aa72511d177 499 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 13 498 2.5E-199 T 14-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Tharo_1931 d600c75ef7678f245f02958cef025d4f 380 SMART SM00463 284 368 4.9E-14 T 14-10-2018 IPR002625 Smr domain Tharo_1931 d600c75ef7678f245f02958cef025d4f 380 Gene3D G3DSA:3.30.1370.110 241 373 1.6E-40 T 14-10-2018 Tharo_1931 d600c75ef7678f245f02958cef025d4f 380 Pfam PF01713 Smr domain 287 368 1.3E-23 T 14-10-2018 IPR002625 Smr domain Tharo_1931 d600c75ef7678f245f02958cef025d4f 380 SUPERFAMILY SSF160443 285 368 3.27E-17 T 14-10-2018 IPR036063 Smr domain superfamily Tharo_2943 54bbe9e6c93c7e139d03880304ff271d 334 Pfam PF00682 HMGL-like 9 307 8.9E-46 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Tharo_2943 54bbe9e6c93c7e139d03880304ff271d 334 Gene3D G3DSA:3.20.20.70 2 330 3.7E-123 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_2943 54bbe9e6c93c7e139d03880304ff271d 334 SUPERFAMILY SSF51569 4 324 7.62E-64 T 14-10-2018 Tharo_2362 16b5f0a034d279831f5e44ae91de686c 294 SUPERFAMILY SSF53448 4 290 2.48E-91 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_2362 16b5f0a034d279831f5e44ae91de686c 294 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 5 289 1.2E-157 T 14-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 Tharo_2362 16b5f0a034d279831f5e44ae91de686c 294 Pfam PF00483 Nucleotidyl transferase 5 241 1.4E-67 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Tharo_2362 16b5f0a034d279831f5e44ae91de686c 294 Gene3D G3DSA:3.90.550.10 1 294 5.2E-85 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_2473 4ec6d2dbd327e0b02b65794d923ffde3 196 Gene3D G3DSA:3.30.160.150 64 195 2.9E-47 T 14-10-2018 Tharo_2473 4ec6d2dbd327e0b02b65794d923ffde3 196 Pfam PF04390 Lipopolysaccharide-assembly 67 189 4.0E-14 T 14-10-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 Tharo_2473 4ec6d2dbd327e0b02b65794d923ffde3 196 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 36 194 23.784 T 14-10-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 Tharo_1460 7280535d27f9b649086077b161d37edd 72 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 67 8.7E-36 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_1460 7280535d27f9b649086077b161d37edd 72 Pfam PF01197 Ribosomal protein L31 1 66 1.9E-34 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_1460 7280535d27f9b649086077b161d37edd 72 Gene3D G3DSA:2.30.170.50 1 70 3.1E-35 T 14-10-2018 Tharo_1460 7280535d27f9b649086077b161d37edd 72 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.4E-22 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_1460 7280535d27f9b649086077b161d37edd 72 PRINTS PR01249 Ribosomal protein L31 signature 32 47 1.4E-22 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_1460 7280535d27f9b649086077b161d37edd 72 PRINTS PR01249 Ribosomal protein L31 signature 47 65 1.4E-22 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_1460 7280535d27f9b649086077b161d37edd 72 SUPERFAMILY SSF143800 1 67 2.71E-28 T 14-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1460 7280535d27f9b649086077b161d37edd 72 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_1460 7280535d27f9b649086077b161d37edd 72 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 30.302 T 14-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_0645 c361c4238ae49c4ed105187dc31875e1 163 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 1.1E-16 T 14-10-2018 Tharo_0645 c361c4238ae49c4ed105187dc31875e1 163 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 1.1E-16 T 14-10-2018 Tharo_0645 c361c4238ae49c4ed105187dc31875e1 163 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 1.1E-16 T 14-10-2018 Tharo_0645 c361c4238ae49c4ed105187dc31875e1 163 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 76 2.9E-22 T 14-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 Tharo_0645 c361c4238ae49c4ed105187dc31875e1 163 Pfam PF02416 mttA/Hcf106 family 5 53 7.1E-9 T 14-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 Tharo_0645 c361c4238ae49c4ed105187dc31875e1 163 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 142 16.762 T 14-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 Tharo_3315 e01f23b91b652c2c947929a300d84bec 710 Gene3D G3DSA:2.40.170.20 173 710 1.7E-74 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Tharo_3315 e01f23b91b652c2c947929a300d84bec 710 Gene3D G3DSA:2.170.130.10 19 159 1.4E-22 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Tharo_3315 e01f23b91b652c2c947929a300d84bec 710 Pfam PF07715 TonB-dependent Receptor Plug Domain 43 148 5.1E-14 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain Tharo_3315 e01f23b91b652c2c947929a300d84bec 710 SUPERFAMILY SSF56935 19 710 4.27E-102 T 14-10-2018 Tharo_3315 e01f23b91b652c2c947929a300d84bec 710 Pfam PF00593 TonB dependent receptor 261 708 4.0E-46 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Tharo_3368 335ab5f8c3b2fce33f177caedc05bddd 553 ProSitePatterns PS00455 Putative AMP-binding domain signature. 197 208 - T 14-10-2018 IPR020845 AMP-binding, conserved site Tharo_3368 335ab5f8c3b2fce33f177caedc05bddd 553 Pfam PF00501 AMP-binding enzyme 32 444 4.5E-69 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Tharo_3368 335ab5f8c3b2fce33f177caedc05bddd 553 SUPERFAMILY SSF56801 8 539 8.37E-123 T 14-10-2018 Tharo_3368 335ab5f8c3b2fce33f177caedc05bddd 553 Gene3D G3DSA:3.40.50.980 195 363 5.1E-46 T 14-10-2018 Tharo_3368 335ab5f8c3b2fce33f177caedc05bddd 553 Gene3D G3DSA:3.30.300.310 440 545 2.0E-27 T 14-10-2018 Tharo_3368 335ab5f8c3b2fce33f177caedc05bddd 553 Pfam PF13193 AMP-binding enzyme C-terminal domain 453 529 1.7E-10 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Tharo_3368 335ab5f8c3b2fce33f177caedc05bddd 553 Gene3D G3DSA:3.40.50.980 22 194 4.6E-43 T 14-10-2018 Tharo_3368 335ab5f8c3b2fce33f177caedc05bddd 553 Gene3D G3DSA:2.30.38.10 364 438 4.3E-22 T 14-10-2018 Tharo_2562 7348d44ef80a04aa93c1d39f18d4913b 656 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 391 620 8.4E-20 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Tharo_2562 7348d44ef80a04aa93c1d39f18d4913b 656 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 12 345 1.2E-44 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 Tharo_2562 7348d44ef80a04aa93c1d39f18d4913b 656 Gene3D G3DSA:3.20.20.70 5 387 4.4E-85 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_2562 7348d44ef80a04aa93c1d39f18d4913b 656 SUPERFAMILY SSF51905 368 656 4.32E-36 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_2562 7348d44ef80a04aa93c1d39f18d4913b 656 SUPERFAMILY SSF51395 7 376 1.07E-79 T 14-10-2018 Tharo_2562 7348d44ef80a04aa93c1d39f18d4913b 656 Gene3D G3DSA:3.50.50.60 491 612 5.1E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_2562 7348d44ef80a04aa93c1d39f18d4913b 656 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 480 488 8.5E-8 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_2562 7348d44ef80a04aa93c1d39f18d4913b 656 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 392 414 8.5E-8 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_2562 7348d44ef80a04aa93c1d39f18d4913b 656 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 516 540 8.5E-8 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_2562 7348d44ef80a04aa93c1d39f18d4913b 656 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 393 412 6.1E-10 T 14-10-2018 Tharo_2562 7348d44ef80a04aa93c1d39f18d4913b 656 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 604 620 6.1E-10 T 14-10-2018 Tharo_2562 7348d44ef80a04aa93c1d39f18d4913b 656 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 520 538 6.1E-10 T 14-10-2018 Tharo_2562 7348d44ef80a04aa93c1d39f18d4913b 656 Gene3D G3DSA:3.40.50.720 392 651 5.1E-57 T 14-10-2018 Tharo_1284 51ef74fbe5bd5e688214778b0b58a89c 378 Gene3D G3DSA:2.130.10.10 31 376 1.7E-116 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Tharo_1284 51ef74fbe5bd5e688214778b0b58a89c 378 TIGRFAM TIGR03907 QH_beta: quinohemoprotein amine dehydrogenase, beta subunit 40 373 3.9E-100 T 14-10-2018 IPR023879 Quinohemoprotein amine dehydrogenase, beta subunit Tharo_1284 51ef74fbe5bd5e688214778b0b58a89c 378 SUPERFAMILY SSF50969 40 365 9.02E-37 T 14-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like Tharo_0241 54541d5c0cdae50d16e32cf0db3bf094 214 SUPERFAMILY SSF52833 1 86 6.16E-27 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_0241 54541d5c0cdae50d16e32cf0db3bf094 214 SUPERFAMILY SSF47616 82 213 7.25E-31 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily Tharo_0241 54541d5c0cdae50d16e32cf0db3bf094 214 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 81 1.7E-19 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 Tharo_0241 54541d5c0cdae50d16e32cf0db3bf094 214 Gene3D G3DSA:3.40.30.10 1 89 3.5E-29 T 14-10-2018 Tharo_0241 54541d5c0cdae50d16e32cf0db3bf094 214 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 2 213 1.9E-91 T 14-10-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-204174|Reactome: R-HSA-71182 Tharo_0241 54541d5c0cdae50d16e32cf0db3bf094 214 Gene3D G3DSA:1.20.1050.10 90 214 2.1E-52 T 14-10-2018 Tharo_2454 52066f772d9b77a3c273d31f82c35ff3 267 Gene3D G3DSA:3.40.50.150 3 196 1.5E-65 T 14-10-2018 Tharo_2454 52066f772d9b77a3c273d31f82c35ff3 267 Gene3D G3DSA:1.10.8.100 201 266 5.9E-22 T 14-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 Tharo_2454 52066f772d9b77a3c273d31f82c35ff3 267 Pfam PF00398 Ribosomal RNA adenine dimethylase 9 261 5.7E-56 T 14-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm Tharo_2454 52066f772d9b77a3c273d31f82c35ff3 267 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 9 264 56.097 T 14-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 Tharo_2454 52066f772d9b77a3c273d31f82c35ff3 267 SMART SM00650 25 197 1.1E-78 T 14-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 Tharo_2454 52066f772d9b77a3c273d31f82c35ff3 267 SUPERFAMILY SSF53335 17 263 1.48E-75 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_2454 52066f772d9b77a3c273d31f82c35ff3 267 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 41 68 - T 14-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 Tharo_2454 52066f772d9b77a3c273d31f82c35ff3 267 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 9 262 5.4E-82 T 14-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 Tharo_1499 b85b629cf176912d4ee5dae638c22be6 316 Pfam PF07859 alpha/beta hydrolase fold 83 288 3.8E-71 T 14-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 Tharo_1499 b85b629cf176912d4ee5dae638c22be6 316 SUPERFAMILY SSF53474 34 312 7.61E-71 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_1499 b85b629cf176912d4ee5dae638c22be6 316 Gene3D G3DSA:3.40.50.1820 1 313 1.7E-94 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_2239 4611d36bde96f5bca8c7997abe3f819c 295 Gene3D G3DSA:1.10.40.60 91 184 4.5E-13 T 14-10-2018 IPR038072 GspK, central domain superfamily Tharo_2239 4611d36bde96f5bca8c7997abe3f819c 295 Pfam PF03934 Type II secretion system (T2SS), protein K 25 230 8.5E-21 T 14-10-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 Tharo_2239 4611d36bde96f5bca8c7997abe3f819c 295 SUPERFAMILY SSF158544 88 181 3.14E-18 T 14-10-2018 IPR038072 GspK, central domain superfamily Tharo_0200 17d0cf77eed407bb565a996910b2ac3b 546 Gene3D G3DSA:3.40.50.1220 190 351 6.6E-31 T 14-10-2018 Tharo_0200 17d0cf77eed407bb565a996910b2ac3b 546 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 198 323 3.8E-21 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 Tharo_0200 17d0cf77eed407bb565a996910b2ac3b 546 Gene3D G3DSA:3.40.50.970 352 537 8.9E-55 T 14-10-2018 Tharo_0200 17d0cf77eed407bb565a996910b2ac3b 546 SUPERFAMILY SSF52518 6 185 1.06E-48 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_0200 17d0cf77eed407bb565a996910b2ac3b 546 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 388 525 1.1E-38 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Tharo_0200 17d0cf77eed407bb565a996910b2ac3b 546 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 415 434 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 Tharo_0200 17d0cf77eed407bb565a996910b2ac3b 546 SUPERFAMILY SSF52518 358 536 1.24E-55 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_0200 17d0cf77eed407bb565a996910b2ac3b 546 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 179 3.1E-50 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Tharo_0200 17d0cf77eed407bb565a996910b2ac3b 546 Gene3D G3DSA:3.40.50.970 1 188 1.4E-55 T 14-10-2018 Tharo_0200 17d0cf77eed407bb565a996910b2ac3b 546 SUPERFAMILY SSF52467 163 349 7.42E-32 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Tharo_0257 c9ea92c9aaee75ef341b605a53e4b064 229 Pfam PF00027 Cyclic nucleotide-binding domain 37 121 8.6E-16 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Tharo_0257 c9ea92c9aaee75ef341b605a53e4b064 229 SMART SM00419 170 219 5.0E-8 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Tharo_0257 c9ea92c9aaee75ef341b605a53e4b064 229 Gene3D G3DSA:1.10.10.10 147 224 1.1E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0257 c9ea92c9aaee75ef341b605a53e4b064 229 Gene3D G3DSA:2.60.120.10 5 146 4.3E-26 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Tharo_0257 c9ea92c9aaee75ef341b605a53e4b064 229 SMART SM00100 17 135 5.2E-16 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Tharo_0257 c9ea92c9aaee75ef341b605a53e4b064 229 Pfam PF13545 Crp-like helix-turn-helix domain 155 224 1.7E-15 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Tharo_0257 c9ea92c9aaee75ef341b605a53e4b064 229 SUPERFAMILY SSF46785 153 218 5.63E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0257 c9ea92c9aaee75ef341b605a53e4b064 229 SUPERFAMILY SSF51206 12 143 2.62E-24 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like Tharo_0990 caffe0ab482baf49d3fd8439515a1f99 346 SUPERFAMILY SSF47413 22 88 3.44E-5 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_0990 caffe0ab482baf49d3fd8439515a1f99 346 Gene3D G3DSA:1.10.260.40 13 105 4.1E-24 T 14-10-2018 Tharo_0990 caffe0ab482baf49d3fd8439515a1f99 346 Pfam PF13464 Domain of unknown function (DUF4115) 271 344 7.0E-25 T 14-10-2018 IPR025194 Domain of unknown function DUF4115 Tharo_0990 caffe0ab482baf49d3fd8439515a1f99 346 Pfam PF13413 Helix-turn-helix domain 24 84 1.3E-23 T 14-10-2018 Tharo_2998 d90937835feef21f6ecd68c4afeaf73f 336 Gene3D G3DSA:2.130.10.10 228 330 1.1E-6 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Tharo_2998 d90937835feef21f6ecd68c4afeaf73f 336 SUPERFAMILY SSF110296 58 306 2.09E-49 T 14-10-2018 Tharo_2998 d90937835feef21f6ecd68c4afeaf73f 336 Gene3D G3DSA:2.130.10.10 4 227 1.3E-20 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Tharo_2998 d90937835feef21f6ecd68c4afeaf73f 336 Pfam PF02012 BNR/Asp-box repeat 214 223 0.092 T 14-10-2018 IPR002860 BNR repeat Tharo_2998 d90937835feef21f6ecd68c4afeaf73f 336 Pfam PF14870 Photosynthesis system II assembly factor YCF48 94 184 2.2E-16 T 14-10-2018 IPR028203 Photosynthesis system II assembly factor Ycf48/Hcf136-like domain Tharo_3059 3bd8fd024bf506e26aca3ca25ffb7b24 315 Gene3D G3DSA:3.40.50.1220 187 315 3.1E-57 T 14-10-2018 Tharo_3059 3bd8fd024bf506e26aca3ca25ffb7b24 315 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 257 283 - T 14-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 Tharo_3059 3bd8fd024bf506e26aca3ca25ffb7b24 315 SUPERFAMILY SSF52467 191 312 3.63E-47 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Tharo_3059 3bd8fd024bf506e26aca3ca25ffb7b24 315 PIRSF PIRSF000089 1 315 6.0E-107 T 14-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 Tharo_3059 3bd8fd024bf506e26aca3ca25ffb7b24 315 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 193 276 3.0E-35 T 14-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 Tharo_3059 3bd8fd024bf506e26aca3ca25ffb7b24 315 Gene3D G3DSA:3.40.50.620 2 186 3.5E-54 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_3059 3bd8fd024bf506e26aca3ca25ffb7b24 315 SUPERFAMILY SSF52402 3 187 4.26E-53 T 14-10-2018 Tharo_3059 3bd8fd024bf506e26aca3ca25ffb7b24 315 SMART SM00893 3 185 5.7E-51 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 Tharo_3059 3bd8fd024bf506e26aca3ca25ffb7b24 315 Pfam PF01012 Electron transfer flavoprotein domain 4 174 3.4E-38 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 Tharo_0770 f4d0cb7db73473d610b3519cf7554a77 287 SUPERFAMILY SSF53335 48 195 5.23E-17 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_0770 f4d0cb7db73473d610b3519cf7554a77 287 Gene3D G3DSA:3.40.50.150 41 209 1.3E-8 T 14-10-2018 Tharo_0770 f4d0cb7db73473d610b3519cf7554a77 287 Pfam PF13679 Methyltransferase domain 42 183 3.4E-43 T 14-10-2018 IPR025714 Methyltransferase domain Tharo_3214 501dfa954d1eb24f1e398d4357bf1628 268 Gene3D G3DSA:3.40.50.11220 41 141 1.2E-27 T 14-10-2018 Tharo_3214 501dfa954d1eb24f1e398d4357bf1628 268 SUPERFAMILY SSF159672 12 196 1.57E-48 T 14-10-2018 IPR038029 GbiG N-terminal domain superfamily KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 Tharo_3214 501dfa954d1eb24f1e398d4357bf1628 268 Pfam PF11761 Cobalamin biosynthesis central region 152 253 1.1E-11 T 14-10-2018 IPR021745 Cobalamin biosynthesis central region KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 Tharo_3214 501dfa954d1eb24f1e398d4357bf1628 268 Pfam PF11760 Cobalamin synthesis G N-terminal 68 146 3.2E-31 T 14-10-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 Tharo_1298 2ea321f8c3d6694ec9637093def8da57 219 SMART SM00116 10 58 2.5E-10 T 14-10-2018 IPR000644 CBS domain Tharo_1298 2ea321f8c3d6694ec9637093def8da57 219 SMART SM00116 85 132 7.1E-12 T 14-10-2018 IPR000644 CBS domain Tharo_1298 2ea321f8c3d6694ec9637093def8da57 219 SUPERFAMILY SSF54631 1 134 1.17E-35 T 14-10-2018 Tharo_1298 2ea321f8c3d6694ec9637093def8da57 219 Gene3D G3DSA:3.10.580.10 1 146 2.3E-44 T 14-10-2018 Tharo_1298 2ea321f8c3d6694ec9637093def8da57 219 SUPERFAMILY SSF55021 144 212 8.46E-6 T 14-10-2018 Tharo_1298 2ea321f8c3d6694ec9637093def8da57 219 Pfam PF00571 CBS domain 3 57 5.2E-14 T 14-10-2018 IPR000644 CBS domain Tharo_1298 2ea321f8c3d6694ec9637093def8da57 219 Pfam PF00571 CBS domain 79 132 5.7E-15 T 14-10-2018 IPR000644 CBS domain Tharo_2507 5706ba15790d8bd8d747103c49243e00 283 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 63 85 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Tharo_2507 5706ba15790d8bd8d747103c49243e00 283 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 29 189 1.8E-33 T 14-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 Tharo_2507 5706ba15790d8bd8d747103c49243e00 283 Pfam PF01066 CDP-alcohol phosphatidyltransferase 22 85 1.2E-13 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Tharo_2507 5706ba15790d8bd8d747103c49243e00 283 Gene3D G3DSA:1.20.120.1760 14 139 1.1E-15 T 14-10-2018 Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 SMART SM00260 438 577 1.6E-14 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 SMART SM00387 302 446 2.1E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 304 445 1.2E-15 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 SUPERFAMILY SSF50341 440 580 9.94E-23 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 Gene3D G3DSA:3.40.50.12740 599 719 8.3E-35 T 14-10-2018 Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 Gene3D G3DSA:1.20.120.160 1 139 2.8E-33 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 SUPERFAMILY SSF47226 7 127 1.16E-28 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 SMART SM00073 5 102 7.9E-22 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 SMART SM01231 171 243 0.0021 T 14-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 Gene3D G3DSA:3.30.565.10 256 445 6.2E-52 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 Pfam PF01584 CheW-like domain 451 579 5.1E-18 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 443 4.2E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 423 4.2E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 PRINTS PR00344 Bacterial sensor protein C-terminal signature 347 361 4.2E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 172 254 6.4E-5 T 14-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 SUPERFAMILY SSF55874 260 444 1.14E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 Gene3D G3DSA:2.30.30.40 446 570 7.2E-21 T 14-10-2018 Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 SMART SM00448 600 714 3.3E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 SUPERFAMILY SSF52172 598 718 3.84E-32 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 Pfam PF00072 Response regulator receiver domain 603 714 4.8E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 Gene3D G3DSA:2.40.50.180 469 532 7.2E-21 T 14-10-2018 Tharo_1016 2cfbb2ceff11109dbbd404565b845814 719 Pfam PF01627 Hpt domain 8 100 1.3E-18 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Tharo_2683 0c6bfb79d7a0f70837430895a922c4aa 305 Gene3D G3DSA:3.40.1030.10 73 305 1.8E-75 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_2683 0c6bfb79d7a0f70837430895a922c4aa 305 Pfam PF02885 Glycosyl transferase family, helical bundle domain 6 66 3.6E-8 T 14-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_2683 0c6bfb79d7a0f70837430895a922c4aa 305 SUPERFAMILY SSF52418 77 302 1.04E-33 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_2683 0c6bfb79d7a0f70837430895a922c4aa 305 Gene3D G3DSA:1.20.970.10 1 72 1.4E-24 T 14-10-2018 Tharo_2683 0c6bfb79d7a0f70837430895a922c4aa 305 SUPERFAMILY SSF47648 7 70 7.06E-12 T 14-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_3293 25d4728b1e05fa4c6d3daec4cdb0443a 362 Gene3D G3DSA:1.10.340.30 19 130 6.7E-85 T 14-10-2018 Tharo_3293 25d4728b1e05fa4c6d3daec4cdb0443a 362 Pfam PF14815 NUDIX domain 234 345 1.9E-22 T 14-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 Tharo_3293 25d4728b1e05fa4c6d3daec4cdb0443a 362 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 165 1.9E-19 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Tharo_3293 25d4728b1e05fa4c6d3daec4cdb0443a 362 Gene3D G3DSA:1.10.1670.10 7 209 6.7E-85 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 Tharo_3293 25d4728b1e05fa4c6d3daec4cdb0443a 362 SUPERFAMILY SSF48150 3 222 5.81E-72 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 Tharo_3293 25d4728b1e05fa4c6d3daec4cdb0443a 362 Pfam PF00633 Helix-hairpin-helix motif 97 126 7.8E-6 T 14-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 Tharo_3293 25d4728b1e05fa4c6d3daec4cdb0443a 362 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 4 262 3.2E-101 T 14-10-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 Tharo_3293 25d4728b1e05fa4c6d3daec4cdb0443a 362 SUPERFAMILY SSF55811 218 346 1.59E-23 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Tharo_3293 25d4728b1e05fa4c6d3daec4cdb0443a 362 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 190 206 - T 14-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 Tharo_3293 25d4728b1e05fa4c6d3daec4cdb0443a 362 SMART SM00478 37 188 8.1E-48 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Tharo_3293 25d4728b1e05fa4c6d3daec4cdb0443a 362 Gene3D G3DSA:3.90.79.10 231 350 1.1E-13 T 14-10-2018 Tharo_3293 25d4728b1e05fa4c6d3daec4cdb0443a 362 ProSitePatterns PS01155 Endonuclease III family signature. 100 129 - T 14-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 Tharo_0894 9b74483908ec2a1cb5ba25b7c977a9b4 107 Pfam PF00581 Rhodanese-like domain 5 98 1.1E-14 T 14-10-2018 IPR001763 Rhodanese-like domain Tharo_0894 9b74483908ec2a1cb5ba25b7c977a9b4 107 SMART SM00450 5 102 1.5E-21 T 14-10-2018 IPR001763 Rhodanese-like domain Tharo_0894 9b74483908ec2a1cb5ba25b7c977a9b4 107 Gene3D G3DSA:3.40.250.10 1 105 3.6E-26 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Tharo_0894 9b74483908ec2a1cb5ba25b7c977a9b4 107 SUPERFAMILY SSF52821 2 104 4.32E-31 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Tharo_1073 8fe24b609e9b3dfc07df69db9377b3d4 364 Gene3D G3DSA:2.40.50.100 73 201 1.3E-77 T 14-10-2018 Tharo_1073 8fe24b609e9b3dfc07df69db9377b3d4 364 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 49 355 8.6E-86 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Tharo_1073 8fe24b609e9b3dfc07df69db9377b3d4 364 Gene3D G3DSA:1.10.287.470 108 167 1.3E-77 T 14-10-2018 Tharo_1073 8fe24b609e9b3dfc07df69db9377b3d4 364 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 59 274 4.5E-32 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Tharo_1073 8fe24b609e9b3dfc07df69db9377b3d4 364 Gene3D G3DSA:2.40.420.20 285 353 1.3E-77 T 14-10-2018 Tharo_1073 8fe24b609e9b3dfc07df69db9377b3d4 364 Gene3D G3DSA:2.40.30.170 62 284 1.3E-77 T 14-10-2018 Tharo_1073 8fe24b609e9b3dfc07df69db9377b3d4 364 SUPERFAMILY SSF111369 64 278 5.23E-45 T 14-10-2018 Tharo_0115 836cfbff7f4860584e05580999b88b1d 512 Gene3D G3DSA:2.40.30.20 1 93 4.2E-34 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Tharo_0115 836cfbff7f4860584e05580999b88b1d 512 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Tharo_0115 836cfbff7f4860584e05580999b88b1d 512 SUPERFAMILY SSF50615 10 94 4.71E-29 T 14-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Tharo_0115 836cfbff7f4860584e05580999b88b1d 512 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 375 1.2E-74 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Tharo_0115 836cfbff7f4860584e05580999b88b1d 512 SUPERFAMILY SSF52540 96 381 1.09E-95 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0115 836cfbff7f4860584e05580999b88b1d 512 PIRSF PIRSF039088 1 512 5.6E-240 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0115 836cfbff7f4860584e05580999b88b1d 512 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 511 2.4E-249 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0115 836cfbff7f4860584e05580999b88b1d 512 Gene3D G3DSA:1.20.150.20 383 511 3.5E-47 T 14-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0115 836cfbff7f4860584e05580999b88b1d 512 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 26 92 1.5E-16 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Tharo_0115 836cfbff7f4860584e05580999b88b1d 512 SUPERFAMILY SSF47917 383 511 8.63E-46 T 14-10-2018 Tharo_0115 836cfbff7f4860584e05580999b88b1d 512 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 512 50.757 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0115 836cfbff7f4860584e05580999b88b1d 512 Gene3D G3DSA:3.40.50.300 94 382 5.7E-132 T 14-10-2018 Tharo_0115 836cfbff7f4860584e05580999b88b1d 512 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 2.2E-45 T 14-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0080 27204e131ea5092396e3f84a7d619112 619 Pfam PF00005 ABC transporter 397 546 2.9E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_0080 27204e131ea5092396e3f84a7d619112 619 ProSitePatterns PS00211 ABC transporters family signature. 518 532 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_0080 27204e131ea5092396e3f84a7d619112 619 SUPERFAMILY SSF90123 37 364 2.49E-70 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Tharo_0080 27204e131ea5092396e3f84a7d619112 619 Gene3D G3DSA:3.40.50.300 372 619 1.2E-89 T 14-10-2018 Tharo_0080 27204e131ea5092396e3f84a7d619112 619 Gene3D G3DSA:1.20.1560.10 31 366 4.0E-76 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Tharo_0080 27204e131ea5092396e3f84a7d619112 619 SMART SM00382 406 592 1.1E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0080 27204e131ea5092396e3f84a7d619112 619 SUPERFAMILY SSF52540 372 616 5.21E-85 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0080 27204e131ea5092396e3f84a7d619112 619 Pfam PF00664 ABC transporter transmembrane region 51 328 5.0E-50 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 ProSitePatterns PS01047 Heavy-metal-associated domain. 25 53 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 SUPERFAMILY SSF81665 206 736 4.32E-16 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 440 446 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 Gene3D G3DSA:2.70.150.20 232 342 7.1E-38 T 14-10-2018 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 SUPERFAMILY SSF55008 20 84 2.75E-17 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 156 633 2.0E-127 T 14-10-2018 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 PRINTS PR00943 Copper-transporting ATPase signature 361 375 6.9E-5 T 14-10-2018 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 PRINTS PR00943 Copper-transporting ATPase signature 421 436 6.9E-5 T 14-10-2018 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 PRINTS PR00943 Copper-transporting ATPase signature 228 246 6.9E-5 T 14-10-2018 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 PRINTS PR00943 Copper-transporting ATPase signature 208 227 6.9E-5 T 14-10-2018 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 Pfam PF00702 haloacid dehalogenase-like hydrolase 435 682 3.9E-29 T 14-10-2018 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 Pfam PF00122 E1-E2 ATPase 239 417 3.1E-57 T 14-10-2018 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 210 635 4.0E-65 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 Gene3D G3DSA:3.30.70.100 18 90 4.9E-18 T 14-10-2018 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 175 770 7.1E-176 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 SUPERFAMILY SSF81653 241 338 1.83E-27 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 438 452 3.5E-28 T 14-10-2018 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 691 703 3.5E-28 T 14-10-2018 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 564 575 3.5E-28 T 14-10-2018 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 586 596 3.5E-28 T 14-10-2018 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 668 687 3.5E-28 T 14-10-2018 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 288 302 3.5E-28 T 14-10-2018 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 Pfam PF00403 Heavy-metal-associated domain 23 81 1.2E-10 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 Tharo_2282 8136fd62533881a3c5f36dd6127550fe 777 SUPERFAMILY SSF56784 436 768 4.95E-53 T 14-10-2018 IPR036412 HAD-like superfamily Tharo_3403 bcaa0a691a58ff14d101a9a15b1b123a 88 Gene3D G3DSA:3.30.230.10 1 88 1.8E-22 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Tharo_3403 bcaa0a691a58ff14d101a9a15b1b123a 88 SUPERFAMILY SSF54211 2 86 2.02E-18 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_3403 bcaa0a691a58ff14d101a9a15b1b123a 88 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 4 85 3.3E-16 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 Tharo_3403 bcaa0a691a58ff14d101a9a15b1b123a 88 Pfam PF00825 Ribonuclease P 4 85 2.9E-19 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 Tharo_3403 bcaa0a691a58ff14d101a9a15b1b123a 88 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 1 62 9.0E-12 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 Tharo_3403 bcaa0a691a58ff14d101a9a15b1b123a 88 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 29 43 - T 14-10-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 Tharo_1489 e066893f0e41e681f906946542150ea1 652 Gene3D G3DSA:3.40.50.300 21 287 1.8E-49 T 14-10-2018 Tharo_1489 e066893f0e41e681f906946542150ea1 652 SMART SM00487 19 289 0.0046 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Tharo_1489 e066893f0e41e681f906946542150ea1 652 SMART SM00491 481 615 8.8E-35 T 14-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 Tharo_1489 e066893f0e41e681f906946542150ea1 652 Pfam PF13307 Helicase C-terminal domain 466 628 2.4E-32 T 14-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 Tharo_1489 e066893f0e41e681f906946542150ea1 652 Gene3D G3DSA:3.40.50.300 448 644 6.6E-37 T 14-10-2018 Tharo_1489 e066893f0e41e681f906946542150ea1 652 SUPERFAMILY SSF52540 189 607 1.06E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1489 e066893f0e41e681f906946542150ea1 652 SUPERFAMILY SSF52540 16 612 9.24E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0909 b0b38faccaa98105df741ff345f2f4bf 222 SMART SM00749 69 130 50.0 T 14-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria Tharo_0909 b0b38faccaa98105df741ff345f2f4bf 222 SMART SM00749 145 208 4.0E-10 T 14-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria Tharo_0909 b0b38faccaa98105df741ff345f2f4bf 222 Pfam PF04972 BON domain 75 131 8.2E-8 T 14-10-2018 IPR007055 BON domain Tharo_0909 b0b38faccaa98105df741ff345f2f4bf 222 Pfam PF04972 BON domain 140 204 6.9E-11 T 14-10-2018 IPR007055 BON domain Tharo_2417 2084a50545ac68b41ca09ee26c75a81b 471 SUPERFAMILY SSF47384 230 312 2.16E-15 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_2417 2084a50545ac68b41ca09ee26c75a81b 471 SMART SM00388 246 312 2.6E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_2417 2084a50545ac68b41ca09ee26c75a81b 471 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 355 463 2.1E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2417 2084a50545ac68b41ca09ee26c75a81b 471 Pfam PF00512 His Kinase A (phospho-acceptor) domain 249 311 1.3E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_2417 2084a50545ac68b41ca09ee26c75a81b 471 Gene3D G3DSA:1.10.287.130 196 313 8.1E-21 T 14-10-2018 Tharo_2417 2084a50545ac68b41ca09ee26c75a81b 471 SUPERFAMILY SSF55874 301 465 1.06E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2417 2084a50545ac68b41ca09ee26c75a81b 471 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 5 463 1.4E-147 T 14-10-2018 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 Tharo_2417 2084a50545ac68b41ca09ee26c75a81b 471 Gene3D G3DSA:3.30.565.10 318 469 1.5E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2417 2084a50545ac68b41ca09ee26c75a81b 471 SMART SM00387 355 466 1.7E-33 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2417 2084a50545ac68b41ca09ee26c75a81b 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 445 3.8E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2417 2084a50545ac68b41ca09ee26c75a81b 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 406 3.8E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2417 2084a50545ac68b41ca09ee26c75a81b 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 420 3.8E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2417 2084a50545ac68b41ca09ee26c75a81b 471 SMART SM00304 192 245 2.1E-5 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_0054 55e9a8edbf77d33cc2afa2760cfdd41b 323 Gene3D G3DSA:3.10.25.10 217 320 3.4E-28 T 14-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Tharo_0054 55e9a8edbf77d33cc2afa2760cfdd41b 323 SUPERFAMILY SSF53328 12 214 8.11E-66 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Tharo_0054 55e9a8edbf77d33cc2afa2760cfdd41b 323 Gene3D G3DSA:3.40.50.170 8 216 4.2E-78 T 14-10-2018 Tharo_0054 55e9a8edbf77d33cc2afa2760cfdd41b 323 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 12 317 2.4E-85 T 14-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 Tharo_0054 55e9a8edbf77d33cc2afa2760cfdd41b 323 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 12 312 35.243 T 14-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 Tharo_0054 55e9a8edbf77d33cc2afa2760cfdd41b 323 Pfam PF00551 Formyl transferase 13 191 6.3E-45 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Tharo_0054 55e9a8edbf77d33cc2afa2760cfdd41b 323 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 143 166 - T 14-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Tharo_0054 55e9a8edbf77d33cc2afa2760cfdd41b 323 Pfam PF02911 Formyl transferase, C-terminal domain 214 309 1.6E-26 T 14-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Tharo_0054 55e9a8edbf77d33cc2afa2760cfdd41b 323 SUPERFAMILY SSF50486 215 317 7.26E-31 T 14-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 Tharo_0236 b287935a9076a9b655340dc5088a2089 144 Pfam PF02082 Transcriptional regulator 1 83 2.6E-23 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type Tharo_0236 b287935a9076a9b655340dc5088a2089 144 Gene3D G3DSA:1.10.10.10 1 140 5.2E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0236 b287935a9076a9b655340dc5088a2089 144 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 128 1.5E-34 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type Tharo_0236 b287935a9076a9b655340dc5088a2089 144 SUPERFAMILY SSF46785 2 132 1.34E-34 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0236 b287935a9076a9b655340dc5088a2089 144 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 14-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site Tharo_1886 62fca0c1fde3962ec53b4ecdf67b382e 294 Gene3D G3DSA:2.60.200.30 129 264 1.6E-90 T 14-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 Tharo_1886 62fca0c1fde3962ec53b4ecdf67b382e 294 Gene3D G3DSA:3.40.50.10330 25 287 1.6E-90 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 Tharo_1886 62fca0c1fde3962ec53b4ecdf67b382e 294 Pfam PF01513 ATP-NAD kinase 57 270 1.1E-58 T 14-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 Tharo_1886 62fca0c1fde3962ec53b4ecdf67b382e 294 SUPERFAMILY SSF111331 7 290 2.75E-87 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily Tharo_1886 62fca0c1fde3962ec53b4ecdf67b382e 294 Hamap MF_00361 NAD kinase [nadK]. 6 287 33.448 T 14-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 Tharo_0662 add01d91c4e926f14765b4baf20571fa 505 SUPERFAMILY SSF54680 421 498 2.49E-14 T 14-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0662 add01d91c4e926f14765b4baf20571fa 505 SUPERFAMILY SSF47648 99 167 5.1E-13 T 14-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0662 add01d91c4e926f14765b4baf20571fa 505 SUPERFAMILY SSF52418 167 419 2.62E-71 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0662 add01d91c4e926f14765b4baf20571fa 505 Gene3D G3DSA:3.90.1170.30 426 502 6.3E-17 T 14-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0662 add01d91c4e926f14765b4baf20571fa 505 PIRSF PIRSF000478 98 504 3.0E-115 T 14-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0662 add01d91c4e926f14765b4baf20571fa 505 Pfam PF02885 Glycosyl transferase family, helical bundle domain 109 162 9.9E-9 T 14-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0662 add01d91c4e926f14765b4baf20571fa 505 SMART SM00941 434 501 9.6E-16 T 14-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0662 add01d91c4e926f14765b4baf20571fa 505 Gene3D G3DSA:1.20.970.50 106 338 1.9E-105 T 14-10-2018 Tharo_0662 add01d91c4e926f14765b4baf20571fa 505 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 16 496 5.4E-174 T 14-10-2018 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 Tharo_0662 add01d91c4e926f14765b4baf20571fa 505 Hamap MF_00703 Putative thymidine phosphorylase. 13 505 63.881 T 14-10-2018 IPR028579 Putative thymidine phosphorylase KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181 Tharo_0662 add01d91c4e926f14765b4baf20571fa 505 Gene3D G3DSA:3.40.1030.10 164 414 1.9E-105 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0662 add01d91c4e926f14765b4baf20571fa 505 Pfam PF00591 Glycosyl transferase family, a/b domain 173 401 1.2E-14 T 14-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0662 add01d91c4e926f14765b4baf20571fa 505 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 207 222 - T 14-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0662 add01d91c4e926f14765b4baf20571fa 505 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 437 495 7.3E-8 T 14-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_1520 2bc962c42658141aadf117334fdcbd5d 394 SUPERFAMILY SSF53187 2 386 1.85E-84 T 14-10-2018 Tharo_1520 2bc962c42658141aadf117334fdcbd5d 394 SUPERFAMILY SSF55031 183 296 1.11E-33 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain Tharo_1520 2bc962c42658141aadf117334fdcbd5d 394 PIRSF PIRSF005962 1 389 2.4E-129 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 Tharo_1520 2bc962c42658141aadf117334fdcbd5d 394 Pfam PF07687 Peptidase dimerisation domain 186 281 1.9E-9 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain Tharo_1520 2bc962c42658141aadf117334fdcbd5d 394 Gene3D G3DSA:3.40.630.10 15 371 7.7E-138 T 14-10-2018 Tharo_1520 2bc962c42658141aadf117334fdcbd5d 394 Pfam PF01546 Peptidase family M20/M25/M40 73 383 6.0E-36 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 Tharo_1520 2bc962c42658141aadf117334fdcbd5d 394 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 374 5.6E-110 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 Tharo_1520 2bc962c42658141aadf117334fdcbd5d 394 Gene3D G3DSA:3.30.70.360 181 295 7.7E-138 T 14-10-2018 Tharo_2659 d5b32526038f9c8bfdab176153e5713e 90 SMART SM00411 1 90 1.0E-37 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Tharo_2659 d5b32526038f9c8bfdab176153e5713e 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.2E-17 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Tharo_2659 d5b32526038f9c8bfdab176153e5713e 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.2E-17 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Tharo_2659 d5b32526038f9c8bfdab176153e5713e 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.2E-17 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Tharo_2659 d5b32526038f9c8bfdab176153e5713e 90 Gene3D G3DSA:4.10.520.10 1 90 1.7E-34 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Tharo_2659 d5b32526038f9c8bfdab176153e5713e 90 SUPERFAMILY SSF47729 1 90 1.91E-31 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Tharo_2659 d5b32526038f9c8bfdab176153e5713e 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.5E-32 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Tharo_2659 d5b32526038f9c8bfdab176153e5713e 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 Tharo_0242 f5c1cc5dab732509ded26ceb46403aab 660 Gene3D G3DSA:3.30.300.30 530 657 2.5E-14 T 14-10-2018 Tharo_0242 f5c1cc5dab732509ded26ceb46403aab 660 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 4 659 3.1E-290 T 14-10-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 Tharo_0242 f5c1cc5dab732509ded26ceb46403aab 660 Gene3D G3DSA:3.40.50.12780 77 526 1.3E-57 T 14-10-2018 Tharo_0242 f5c1cc5dab732509ded26ceb46403aab 660 ProSitePatterns PS00455 Putative AMP-binding domain signature. 274 285 - T 14-10-2018 IPR020845 AMP-binding, conserved site Tharo_0242 f5c1cc5dab732509ded26ceb46403aab 660 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 38 97 1.7E-6 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 Tharo_0242 f5c1cc5dab732509ded26ceb46403aab 660 Pfam PF00501 AMP-binding enzyme 104 530 1.4E-46 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Tharo_0242 f5c1cc5dab732509ded26ceb46403aab 660 SUPERFAMILY SSF56801 24 648 4.84E-122 T 14-10-2018 Tharo_1001 f24dec2d45be4f3ad7d8fb234127c259 385 Gene3D G3DSA:3.30.930.10 3 317 1.2E-63 T 14-10-2018 Tharo_1001 f24dec2d45be4f3ad7d8fb234127c259 385 PIRSF PIRSF001549 3 328 3.0E-35 T 14-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Tharo_1001 f24dec2d45be4f3ad7d8fb234127c259 385 Pfam PF13393 Histidyl-tRNA synthetase 9 312 1.5E-116 T 14-10-2018 Tharo_1001 f24dec2d45be4f3ad7d8fb234127c259 385 SUPERFAMILY SSF55681 5 313 3.04E-57 T 14-10-2018 Tharo_1001 f24dec2d45be4f3ad7d8fb234127c259 385 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 10 313 1.3E-84 T 14-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 Tharo_1001 f24dec2d45be4f3ad7d8fb234127c259 385 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 15 364 33.466 T 14-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 Tharo_2403 aa3083a68565d38dd35b4dcfd01ff308 416 SUPERFAMILY SSF63882 14 185 1.7E-53 T 14-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Tharo_2403 aa3083a68565d38dd35b4dcfd01ff308 416 Gene3D G3DSA:3.90.105.10 35 184 4.6E-138 T 14-10-2018 Tharo_2403 aa3083a68565d38dd35b4dcfd01ff308 416 Pfam PF03454 MoeA C-terminal region (domain IV) 342 412 2.6E-19 T 14-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Tharo_2403 aa3083a68565d38dd35b4dcfd01ff308 416 Gene3D G3DSA:3.40.980.10 185 337 4.6E-138 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily Tharo_2403 aa3083a68565d38dd35b4dcfd01ff308 416 Gene3D G3DSA:2.170.190.11 58 151 4.6E-138 T 14-10-2018 Tharo_2403 aa3083a68565d38dd35b4dcfd01ff308 416 Gene3D G3DSA:2.40.340.10 338 407 4.6E-138 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Tharo_2403 aa3083a68565d38dd35b4dcfd01ff308 416 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 187 321 9.2E-33 T 14-10-2018 IPR001453 MoaB/Mog domain Tharo_2403 aa3083a68565d38dd35b4dcfd01ff308 416 SUPERFAMILY SSF63867 338 415 2.88E-24 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Tharo_2403 aa3083a68565d38dd35b4dcfd01ff308 416 SUPERFAMILY SSF53218 187 331 4.58E-45 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily Tharo_2403 aa3083a68565d38dd35b4dcfd01ff308 416 SMART SM00852 190 327 2.4E-43 T 14-10-2018 IPR001453 MoaB/Mog domain Tharo_2403 aa3083a68565d38dd35b4dcfd01ff308 416 Pfam PF00994 Probable molybdopterin binding domain 192 325 3.4E-29 T 14-10-2018 IPR001453 MoaB/Mog domain Tharo_2403 aa3083a68565d38dd35b4dcfd01ff308 416 Pfam PF03453 MoeA N-terminal region (domain I and II) 17 177 3.5E-42 T 14-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Tharo_1731 6a29b3947ac713ffb01ef7aa7c7e886e 657 PIRSF PIRSF003167 1 657 4.9E-184 T 14-10-2018 IPR016380 Signal transduction histidine kinase, nitrate/nitrite-sensing GO:0000155|GO:0000160|GO:0004673|GO:0016021 Tharo_1731 6a29b3947ac713ffb01ef7aa7c7e886e 657 Pfam PF07730 Histidine kinase 450 516 3.4E-16 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Tharo_1731 6a29b3947ac713ffb01ef7aa7c7e886e 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 612 630 1.0E-5 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1731 6a29b3947ac713ffb01ef7aa7c7e886e 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 591 605 1.0E-5 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1731 6a29b3947ac713ffb01ef7aa7c7e886e 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 636 649 1.0E-5 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1731 6a29b3947ac713ffb01ef7aa7c7e886e 657 Gene3D G3DSA:1.20.1480.50 176 268 1.2E-5 T 14-10-2018 Tharo_1731 6a29b3947ac713ffb01ef7aa7c7e886e 657 SUPERFAMILY SSF55874 521 649 9.3E-21 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1731 6a29b3947ac713ffb01ef7aa7c7e886e 657 Pfam PF00672 HAMP domain 210 258 8.4E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_1731 6a29b3947ac713ffb01ef7aa7c7e886e 657 Pfam PF13185 GAF domain 296 434 5.4E-9 T 14-10-2018 IPR003018 GAF domain GO:0005515 Tharo_1731 6a29b3947ac713ffb01ef7aa7c7e886e 657 Gene3D G3DSA:1.20.120.960 47 175 7.1E-7 T 14-10-2018 Tharo_1731 6a29b3947ac713ffb01ef7aa7c7e886e 657 SMART SM00304 209 261 6.6E-12 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_1731 6a29b3947ac713ffb01ef7aa7c7e886e 657 SMART SM00387 555 652 3.5E-10 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1731 6a29b3947ac713ffb01ef7aa7c7e886e 657 SUPERFAMILY SSF55781 296 446 6.11E-18 T 14-10-2018 Tharo_1731 6a29b3947ac713ffb01ef7aa7c7e886e 657 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 557 651 6.7E-10 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1731 6a29b3947ac713ffb01ef7aa7c7e886e 657 Gene3D G3DSA:3.30.450.40 269 446 4.1E-25 T 14-10-2018 IPR029016 GAF-like domain superfamily Tharo_1731 6a29b3947ac713ffb01ef7aa7c7e886e 657 Gene3D G3DSA:3.30.565.10 516 650 4.0E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1731 6a29b3947ac713ffb01ef7aa7c7e886e 657 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 41 150 6.8E-21 T 14-10-2018 IPR029095 NarX-like, N-terminal Tharo_1731 6a29b3947ac713ffb01ef7aa7c7e886e 657 SUPERFAMILY SSF158472 211 259 9.29E-9 T 14-10-2018 Tharo_1731 6a29b3947ac713ffb01ef7aa7c7e886e 657 SMART SM00065 296 443 5.3E-7 T 14-10-2018 IPR003018 GAF domain GO:0005515 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 Gene3D G3DSA:3.30.70.1430 38 822 0.0 T 14-10-2018 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 Gene3D G3DSA:1.20.1640.10 518 1027 0.0 T 14-10-2018 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 SUPERFAMILY SSF82866 296 497 4.19E-50 T 14-10-2018 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 Gene3D G3DSA:3.30.2090.10 179 275 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 Gene3D G3DSA:3.30.70.1440 674 870 0.0 T 14-10-2018 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 Gene3D G3DSA:3.30.70.1430 572 673 0.0 T 14-10-2018 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 SUPERFAMILY SSF82693 38 131 4.97E-26 T 14-10-2018 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 Gene3D G3DSA:1.20.1640.10 8 517 0.0 T 14-10-2018 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 SUPERFAMILY SSF82693 570 674 1.1E-30 T 14-10-2018 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1046 0.0 T 14-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 SUPERFAMILY SSF82714 727 814 1.57E-22 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 SUPERFAMILY SSF82693 135 330 6.63E-29 T 14-10-2018 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 Gene3D G3DSA:3.30.70.1320 133 332 0.0 T 14-10-2018 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 3.1E-110 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 PRINTS PR00702 Acriflavin resistance protein family signature 626 640 3.1E-110 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 3.1E-110 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 3.1E-110 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 3.1E-110 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 3.1E-110 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 PRINTS PR00702 Acriflavin resistance protein family signature 557 574 3.1E-110 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 3.1E-110 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 3.1E-110 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 SUPERFAMILY SSF82866 811 1035 3.01E-41 T 14-10-2018 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 SUPERFAMILY SSF82714 182 272 2.49E-21 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 Pfam PF00873 AcrB/AcrD/AcrF family 1 1030 0.0 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_3180 ede05a0f06c4775d123ee8baf0aca9cf 1051 Gene3D G3DSA:3.30.2090.10 726 814 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_0295 cf283a0bd03c0b49671e0dbb6e39d535 672 Gene3D G3DSA:2.40.170.20 28 672 4.6E-128 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Tharo_0295 cf283a0bd03c0b49671e0dbb6e39d535 672 Pfam PF07715 TonB-dependent Receptor Plug Domain 34 137 6.4E-17 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain Tharo_0295 cf283a0bd03c0b49671e0dbb6e39d535 672 Pfam PF00593 TonB dependent receptor 221 667 4.1E-41 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Tharo_0295 cf283a0bd03c0b49671e0dbb6e39d535 672 SUPERFAMILY SSF56935 15 671 1.37E-107 T 14-10-2018 Tharo_2250 70631750389b83e2447e84a76d9aec2f 299 PIRSF PIRSF000410 13 292 4.0E-96 T 14-10-2018 IPR026024 Chemotaxis protein methyltransferase CheR Tharo_2250 70631750389b83e2447e84a76d9aec2f 299 SUPERFAMILY SSF53335 98 289 1.13E-54 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_2250 70631750389b83e2447e84a76d9aec2f 299 PRINTS PR00996 Glutamate methyltransferase family signature 126 146 1.3E-44 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_2250 70631750389b83e2447e84a76d9aec2f 299 PRINTS PR00996 Glutamate methyltransferase family signature 53 66 1.3E-44 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_2250 70631750389b83e2447e84a76d9aec2f 299 PRINTS PR00996 Glutamate methyltransferase family signature 91 103 1.3E-44 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_2250 70631750389b83e2447e84a76d9aec2f 299 PRINTS PR00996 Glutamate methyltransferase family signature 232 246 1.3E-44 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_2250 70631750389b83e2447e84a76d9aec2f 299 PRINTS PR00996 Glutamate methyltransferase family signature 251 274 1.3E-44 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_2250 70631750389b83e2447e84a76d9aec2f 299 PRINTS PR00996 Glutamate methyltransferase family signature 160 176 1.3E-44 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_2250 70631750389b83e2447e84a76d9aec2f 299 Pfam PF01739 CheR methyltransferase, SAM binding domain 98 289 1.8E-59 T 14-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal Tharo_2250 70631750389b83e2447e84a76d9aec2f 299 Pfam PF03705 CheR methyltransferase, all-alpha domain 33 83 1.5E-17 T 14-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal Tharo_2250 70631750389b83e2447e84a76d9aec2f 299 Gene3D G3DSA:3.40.50.150 97 292 4.5E-67 T 14-10-2018 Tharo_2250 70631750389b83e2447e84a76d9aec2f 299 SMART SM00138 31 292 2.0E-98 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_2250 70631750389b83e2447e84a76d9aec2f 299 Gene3D G3DSA:1.10.155.10 19 96 1.8E-24 T 14-10-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily Tharo_2250 70631750389b83e2447e84a76d9aec2f 299 SUPERFAMILY SSF47757 23 97 7.19E-20 T 14-10-2018 Tharo_0179 b377c81541928b49e0475c97dbebe693 668 Gene3D G3DSA:3.40.228.10 101 294 3.1E-149 T 14-10-2018 Tharo_0179 b377c81541928b49e0475c97dbebe693 668 Gene3D G3DSA:2.40.40.20 503 657 4.0E-49 T 14-10-2018 Tharo_0179 b377c81541928b49e0475c97dbebe693 668 Gene3D G3DSA:3.40.50.740 16 471 3.1E-149 T 14-10-2018 Tharo_0179 b377c81541928b49e0475c97dbebe693 668 Pfam PF00384 Molybdopterin oxidoreductase 16 437 1.0E-52 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_0179 b377c81541928b49e0475c97dbebe693 668 Pfam PF01568 Molydopterin dinucleotide binding domain 532 646 1.5E-22 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 Tharo_0179 b377c81541928b49e0475c97dbebe693 668 SUPERFAMILY SSF50692 493 656 2.94E-38 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Tharo_0179 b377c81541928b49e0475c97dbebe693 668 SUPERFAMILY SSF53706 8 534 1.7E-136 T 14-10-2018 Tharo_2801 2ce29cc271c7f58ad516c39955423e53 645 Gene3D G3DSA:3.20.20.450 404 641 2.1E-46 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_2801 2ce29cc271c7f58ad516c39955423e53 645 Pfam PF00563 EAL domain 409 637 9.7E-45 T 14-10-2018 IPR001633 EAL domain Tharo_2801 2ce29cc271c7f58ad516c39955423e53 645 SMART SM00304 170 221 1.0E-4 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_2801 2ce29cc271c7f58ad516c39955423e53 645 Pfam PF00990 Diguanylate cyclase, GGDEF domain 234 386 4.6E-18 T 14-10-2018 IPR000160 GGDEF domain Tharo_2801 2ce29cc271c7f58ad516c39955423e53 645 SMART SM00267 223 392 7.8E-13 T 14-10-2018 IPR000160 GGDEF domain Tharo_2801 2ce29cc271c7f58ad516c39955423e53 645 SUPERFAMILY SSF141868 410 637 9.55E-44 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_2801 2ce29cc271c7f58ad516c39955423e53 645 Gene3D G3DSA:3.30.1040.50 100 149 1.8E-18 T 14-10-2018 Tharo_2801 2ce29cc271c7f58ad516c39955423e53 645 SUPERFAMILY SSF55073 239 388 1.02E-17 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_2801 2ce29cc271c7f58ad516c39955423e53 645 Pfam PF16448 LapD/MoxY periplasmic domain 23 144 8.2E-43 T 14-10-2018 IPR032244 LapD/MoxY, periplasmic domain Tharo_2801 2ce29cc271c7f58ad516c39955423e53 645 SMART SM00052 403 639 1.7E-14 T 14-10-2018 IPR001633 EAL domain Tharo_2801 2ce29cc271c7f58ad516c39955423e53 645 Gene3D G3DSA:3.30.70.270 218 391 9.4E-25 T 14-10-2018 Tharo_2801 2ce29cc271c7f58ad516c39955423e53 645 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 230 388 5.0E-12 T 14-10-2018 IPR000160 GGDEF domain Tharo_2500 492d9739dd7007f32eb0e916225012fb 298 Gene3D G3DSA:3.40.50.620 3 152 3.1E-25 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_2500 492d9739dd7007f32eb0e916225012fb 298 Gene3D G3DSA:3.40.50.620 153 297 2.2E-29 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_2500 492d9739dd7007f32eb0e916225012fb 298 SUPERFAMILY SSF52402 153 293 2.26E-27 T 14-10-2018 Tharo_2500 492d9739dd7007f32eb0e916225012fb 298 SUPERFAMILY SSF52402 5 146 6.7E-26 T 14-10-2018 Tharo_2500 492d9739dd7007f32eb0e916225012fb 298 PRINTS PR01438 Universal stress protein signature 153 171 2.9E-14 T 14-10-2018 IPR006015 Universal stress protein A Tharo_2500 492d9739dd7007f32eb0e916225012fb 298 PRINTS PR01438 Universal stress protein signature 272 294 2.9E-14 T 14-10-2018 IPR006015 Universal stress protein A Tharo_2500 492d9739dd7007f32eb0e916225012fb 298 PRINTS PR01438 Universal stress protein signature 254 266 2.9E-14 T 14-10-2018 IPR006015 Universal stress protein A Tharo_2500 492d9739dd7007f32eb0e916225012fb 298 Pfam PF00582 Universal stress protein family 153 292 6.4E-23 T 14-10-2018 IPR006016 UspA Tharo_2500 492d9739dd7007f32eb0e916225012fb 298 Pfam PF00582 Universal stress protein family 5 146 9.3E-20 T 14-10-2018 IPR006016 UspA Tharo_0076 38c0797b686cd218abdfbf6e097949d4 443 SMART SM00116 282 330 0.43 T 14-10-2018 IPR000644 CBS domain Tharo_0076 38c0797b686cd218abdfbf6e097949d4 443 SMART SM00116 220 269 12.0 T 14-10-2018 IPR000644 CBS domain Tharo_0076 38c0797b686cd218abdfbf6e097949d4 443 Gene3D G3DSA:3.30.465.10 345 425 1.2E-34 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Tharo_0076 38c0797b686cd218abdfbf6e097949d4 443 Gene3D G3DSA:3.10.580.10 192 344 5.4E-44 T 14-10-2018 Tharo_0076 38c0797b686cd218abdfbf6e097949d4 443 Pfam PF00571 CBS domain 283 327 8.8E-6 T 14-10-2018 IPR000644 CBS domain Tharo_0076 38c0797b686cd218abdfbf6e097949d4 443 Pfam PF00571 CBS domain 217 265 0.0015 T 14-10-2018 IPR000644 CBS domain Tharo_0076 38c0797b686cd218abdfbf6e097949d4 443 SMART SM01091 344 426 4.0E-30 T 14-10-2018 IPR005170 Transporter-associated domain Tharo_0076 38c0797b686cd218abdfbf6e097949d4 443 SUPERFAMILY SSF54631 198 332 4.93E-27 T 14-10-2018 Tharo_0076 38c0797b686cd218abdfbf6e097949d4 443 Pfam PF01595 Domain of unknown function DUF21 5 196 2.9E-44 T 14-10-2018 IPR002550 CNNM, transmembrane domain Tharo_0076 38c0797b686cd218abdfbf6e097949d4 443 SUPERFAMILY SSF56176 344 424 6.54E-23 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Tharo_0076 38c0797b686cd218abdfbf6e097949d4 443 Pfam PF03471 Transporter associated domain 345 424 4.7E-22 T 14-10-2018 IPR005170 Transporter-associated domain Tharo_1936 bce92ae155c77dbd72b3eeebfcd191fd 455 Gene3D G3DSA:1.10.3710.10 338 438 5.5E-33 T 14-10-2018 Tharo_1936 bce92ae155c77dbd72b3eeebfcd191fd 455 SUPERFAMILY SSF48019 244 426 7.37E-70 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 Tharo_1936 bce92ae155c77dbd72b3eeebfcd191fd 455 Pfam PF16193 AAA C-terminal domain 184 259 3.9E-20 T 14-10-2018 IPR032423 AAA C-terminal domain Tharo_1936 bce92ae155c77dbd72b3eeebfcd191fd 455 SUPERFAMILY SSF52540 7 217 5.1E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1936 bce92ae155c77dbd72b3eeebfcd191fd 455 Pfam PF12002 MgsA AAA+ ATPase C terminal 260 426 2.8E-64 T 14-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal Tharo_1936 bce92ae155c77dbd72b3eeebfcd191fd 455 SMART SM00382 48 167 1.2E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1936 bce92ae155c77dbd72b3eeebfcd191fd 455 Gene3D G3DSA:1.20.272.10 233 337 3.3E-41 T 14-10-2018 Tharo_1936 bce92ae155c77dbd72b3eeebfcd191fd 455 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 52 158 1.1E-13 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Tharo_1936 bce92ae155c77dbd72b3eeebfcd191fd 455 Gene3D G3DSA:3.40.50.300 5 162 1.5E-44 T 14-10-2018 Tharo_0479 13facc34d1e9e2b5a4fb97ecfaac685b 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 49 71 2.5E-28 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Tharo_0479 13facc34d1e9e2b5a4fb97ecfaac685b 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 148 165 2.5E-28 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Tharo_0479 13facc34d1e9e2b5a4fb97ecfaac685b 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 298 312 2.5E-28 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Tharo_0479 13facc34d1e9e2b5a4fb97ecfaac685b 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 274 279 2.5E-28 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Tharo_0479 13facc34d1e9e2b5a4fb97ecfaac685b 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 233 242 2.5E-28 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Tharo_0479 13facc34d1e9e2b5a4fb97ecfaac685b 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 87 96 2.5E-28 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Tharo_0479 13facc34d1e9e2b5a4fb97ecfaac685b 319 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 12 319 39.659 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Tharo_0479 13facc34d1e9e2b5a4fb97ecfaac685b 319 Gene3D G3DSA:3.40.50.1370 20 312 6.8E-86 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Tharo_0479 13facc34d1e9e2b5a4fb97ecfaac685b 319 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 13 317 6.3E-89 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Tharo_0479 13facc34d1e9e2b5a4fb97ecfaac685b 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 149 160 2.4E-17 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Tharo_0479 13facc34d1e9e2b5a4fb97ecfaac685b 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 59 78 2.4E-17 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Tharo_0479 13facc34d1e9e2b5a4fb97ecfaac685b 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 279 2.4E-17 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Tharo_0479 13facc34d1e9e2b5a4fb97ecfaac685b 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 282 305 2.4E-17 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Tharo_0479 13facc34d1e9e2b5a4fb97ecfaac685b 319 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 59 66 - T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Tharo_0479 13facc34d1e9e2b5a4fb97ecfaac685b 319 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 169 315 2.5E-23 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 Tharo_0479 13facc34d1e9e2b5a4fb97ecfaac685b 319 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 13 161 1.1E-36 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 Tharo_0479 13facc34d1e9e2b5a4fb97ecfaac685b 319 Gene3D G3DSA:3.40.50.1370 149 296 6.8E-86 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Tharo_0479 13facc34d1e9e2b5a4fb97ecfaac685b 319 SUPERFAMILY SSF53671 12 316 3.93E-89 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Tharo_2427 b02cab40d104241ff5c7f71b3a24f761 322 SUPERFAMILY SSF161111 21 241 3.92E-50 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Tharo_2427 b02cab40d104241ff5c7f71b3a24f761 322 Pfam PF01545 Cation efflux family 27 240 5.2E-38 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Tharo_2427 b02cab40d104241ff5c7f71b3a24f761 322 Gene3D G3DSA:1.20.1510.10 21 240 1.2E-29 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Tharo_2427 b02cab40d104241ff5c7f71b3a24f761 322 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 23 317 1.3E-63 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Tharo_2387 1807bd57f4afeb30cdfa712d49245456 460 SUPERFAMILY SSF50156 91 184 1.86E-20 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 Tharo_2387 1807bd57f4afeb30cdfa712d49245456 460 Gene3D G3DSA:3.90.226.10 189 377 1.3E-89 T 14-10-2018 Tharo_2387 1807bd57f4afeb30cdfa712d49245456 460 SMART SM00245 174 380 8.0E-67 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 Tharo_2387 1807bd57f4afeb30cdfa712d49245456 460 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 54 384 7.4E-97 T 14-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 Tharo_2387 1807bd57f4afeb30cdfa712d49245456 460 Gene3D G3DSA:2.30.42.10 101 188 1.3E-89 T 14-10-2018 Tharo_2387 1807bd57f4afeb30cdfa712d49245456 460 SMART SM00228 101 172 6.8E-16 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Tharo_2387 1807bd57f4afeb30cdfa712d49245456 460 Pfam PF13180 PDZ domain 101 181 1.2E-12 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Tharo_2387 1807bd57f4afeb30cdfa712d49245456 460 SUPERFAMILY SSF52096 40 384 8.12E-77 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_2387 1807bd57f4afeb30cdfa712d49245456 460 Pfam PF03572 Peptidase family S41 200 379 1.0E-54 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 Tharo_2387 1807bd57f4afeb30cdfa712d49245456 460 Gene3D G3DSA:3.30.750.44 47 355 1.3E-89 T 14-10-2018 Tharo_2366 5fbb082e1bb01315e6105f27ddf80eeb 140 Pfam PF01850 PIN domain 4 121 2.8E-5 T 14-10-2018 IPR002716 PIN domain Tharo_2366 5fbb082e1bb01315e6105f27ddf80eeb 140 Gene3D G3DSA:3.40.50.1010 3 131 9.2E-24 T 14-10-2018 Tharo_2366 5fbb082e1bb01315e6105f27ddf80eeb 140 SUPERFAMILY SSF88723 4 125 2.22E-19 T 14-10-2018 IPR029060 PIN-like domain superfamily Tharo_0910 fb6e9d3b01495620b84e40cd8b8ffb39 197 SUPERFAMILY SSF53697 3 190 7.89E-42 T 14-10-2018 Tharo_0910 fb6e9d3b01495620b84e40cd8b8ffb39 197 Gene3D G3DSA:3.40.50.10490 1 195 3.8E-53 T 14-10-2018 Tharo_0910 fb6e9d3b01495620b84e40cd8b8ffb39 197 Pfam PF13580 SIS domain 10 146 6.8E-28 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Tharo_0409 10b34162fdd5f49d9bdd2f02bbfe6674 231 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 200 226 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_0409 10b34162fdd5f49d9bdd2f02bbfe6674 231 PRINTS PR00046 Major sigma-70 factor signature 200 215 4.6E-12 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_0409 10b34162fdd5f49d9bdd2f02bbfe6674 231 PRINTS PR00046 Major sigma-70 factor signature 215 226 4.6E-12 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_0409 10b34162fdd5f49d9bdd2f02bbfe6674 231 PRINTS PR00046 Major sigma-70 factor signature 40 53 4.6E-12 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_0409 10b34162fdd5f49d9bdd2f02bbfe6674 231 PRINTS PR00046 Major sigma-70 factor signature 183 195 4.6E-12 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_0409 10b34162fdd5f49d9bdd2f02bbfe6674 231 SUPERFAMILY SSF88659 86 149 6.54E-13 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Tharo_0409 10b34162fdd5f49d9bdd2f02bbfe6674 231 Pfam PF04545 Sigma-70, region 4 179 228 2.1E-16 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 Tharo_0409 10b34162fdd5f49d9bdd2f02bbfe6674 231 Gene3D G3DSA:1.10.1740.10 2 82 8.0E-29 T 14-10-2018 Tharo_0409 10b34162fdd5f49d9bdd2f02bbfe6674 231 Pfam PF04542 Sigma-70 region 2 13 85 2.9E-15 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Tharo_0409 10b34162fdd5f49d9bdd2f02bbfe6674 231 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 230 3.3E-36 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Tharo_0409 10b34162fdd5f49d9bdd2f02bbfe6674 231 PIRSF PIRSF000770 2 231 2.4E-39 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_0409 10b34162fdd5f49d9bdd2f02bbfe6674 231 SUPERFAMILY SSF88659 158 230 1.31E-19 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Tharo_0409 10b34162fdd5f49d9bdd2f02bbfe6674 231 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 40 53 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_0409 10b34162fdd5f49d9bdd2f02bbfe6674 231 SUPERFAMILY SSF88946 3 85 2.2E-23 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Tharo_0409 10b34162fdd5f49d9bdd2f02bbfe6674 231 Gene3D G3DSA:1.20.140.160 84 231 6.6E-46 T 14-10-2018 Tharo_0409 10b34162fdd5f49d9bdd2f02bbfe6674 231 Pfam PF04539 Sigma-70 region 3 96 145 7.1E-9 T 14-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 Tharo_0409 10b34162fdd5f49d9bdd2f02bbfe6674 231 Hamap MF_00962 RNA polymerase sigma factor FliA [fliA]. 2 231 59.92 T 14-10-2018 IPR028617 RNA polymerase sigma factor FliA GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 Tharo_0409 10b34162fdd5f49d9bdd2f02bbfe6674 231 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 13 230 3.3E-82 T 14-10-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 Tharo_0893 f41bd3c2fefcaabe0122f1df048e76a2 217 Gene3D G3DSA:3.40.50.150 1 209 3.0E-53 T 14-10-2018 Tharo_0893 f41bd3c2fefcaabe0122f1df048e76a2 217 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 132 147 - T 14-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 Tharo_0893 f41bd3c2fefcaabe0122f1df048e76a2 217 SUPERFAMILY SSF53335 1 200 4.91E-46 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_0893 f41bd3c2fefcaabe0122f1df048e76a2 217 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 10 200 1.7E-40 T 14-10-2018 Tharo_0196 81908bc7fe0236df38e462ffabe47e65 204 Pfam PF13577 SnoaL-like domain 12 142 2.6E-20 T 14-10-2018 IPR037401 SnoaL-like domain Tharo_0196 81908bc7fe0236df38e462ffabe47e65 204 SUPERFAMILY SSF54427 4 161 1.94E-21 T 14-10-2018 IPR032710 NTF2-like domain superfamily Tharo_0196 81908bc7fe0236df38e462ffabe47e65 204 Gene3D G3DSA:3.10.450.50 3 159 1.7E-24 T 14-10-2018 Tharo_1218 98fc99d6de3cbdf4551aeb51e1255ced 142 PIRSF PIRSF025560 13 142 4.1E-24 T 14-10-2018 IPR008309 Uncharacterised conserved protein UCP025560 Tharo_1218 98fc99d6de3cbdf4551aeb51e1255ced 142 Pfam PF07027 Protein of unknown function (DUF1318) 45 142 3.9E-23 T 14-10-2018 IPR008309 Uncharacterised conserved protein UCP025560 Tharo_0663 e80f0d1f81168e62793f5adf98a84bd0 452 Gene3D G3DSA:3.40.50.10890 216 393 5.7E-137 T 14-10-2018 Tharo_0663 e80f0d1f81168e62793f5adf98a84bd0 452 Gene3D G3DSA:3.60.15.10 7 428 5.7E-137 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_0663 e80f0d1f81168e62793f5adf98a84bd0 452 Pfam PF10996 Beta-Casp domain 248 367 4.7E-21 T 14-10-2018 IPR022712 Beta-Casp domain Tharo_0663 e80f0d1f81168e62793f5adf98a84bd0 452 SUPERFAMILY SSF56281 2 449 2.1E-128 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_0663 e80f0d1f81168e62793f5adf98a84bd0 452 SMART SM01027 248 367 5.9E-49 T 14-10-2018 IPR022712 Beta-Casp domain Tharo_0663 e80f0d1f81168e62793f5adf98a84bd0 452 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 381 444 3.3E-15 T 14-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain Tharo_0663 e80f0d1f81168e62793f5adf98a84bd0 452 SMART SM00849 14 224 4.7E-7 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_0663 e80f0d1f81168e62793f5adf98a84bd0 452 Pfam PF00753 Metallo-beta-lactamase superfamily 19 208 1.5E-13 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_1206 0ddda35e119fdbdcb3dc2f3e5c0a3900 365 Pfam PF00266 Aminotransferase class-V 4 353 3.8E-54 T 14-10-2018 IPR000192 Aminotransferase class V domain Tharo_1206 0ddda35e119fdbdcb3dc2f3e5c0a3900 365 SUPERFAMILY SSF53383 1 361 2.31E-119 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_1206 0ddda35e119fdbdcb3dc2f3e5c0a3900 365 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 5 363 1.9E-156 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 Tharo_1206 0ddda35e119fdbdcb3dc2f3e5c0a3900 365 Gene3D G3DSA:3.90.1150.10 262 365 1.6E-40 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_1206 0ddda35e119fdbdcb3dc2f3e5c0a3900 365 PIRSF PIRSF000525 1 365 8.4E-154 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 Tharo_1206 0ddda35e119fdbdcb3dc2f3e5c0a3900 365 Gene3D G3DSA:3.40.640.10 17 261 1.4E-91 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_1206 0ddda35e119fdbdcb3dc2f3e5c0a3900 365 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 192 211 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site Tharo_1206 0ddda35e119fdbdcb3dc2f3e5c0a3900 365 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 364 50.762 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 Tharo_2769 3ba9c9f025e29d08382bba70d9209385 368 SUPERFAMILY SSF103088 242 365 9.03E-26 T 14-10-2018 IPR036737 OmpA-like domain superfamily Tharo_2769 3ba9c9f025e29d08382bba70d9209385 368 Gene3D G3DSA:3.30.1330.60 199 368 2.3E-41 T 14-10-2018 IPR036737 OmpA-like domain superfamily Tharo_2769 3ba9c9f025e29d08382bba70d9209385 368 Pfam PF00691 OmpA family 254 359 2.4E-15 T 14-10-2018 IPR006665 OmpA-like domain Tharo_1318 2c997c3766c41ff710e9361b17ba076b 772 SUPERFAMILY SSF56719 41 518 3.14E-148 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Tharo_1318 2c997c3766c41ff710e9361b17ba076b 772 Gene3D G3DSA:2.120.10.90 534 764 4.7E-21 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal Tharo_1318 2c997c3766c41ff710e9361b17ba076b 772 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 21 761 5.2E-236 T 14-10-2018 Tharo_1318 2c997c3766c41ff710e9361b17ba076b 772 Gene3D G3DSA:3.30.1360.40 247 363 9.4E-184 T 14-10-2018 Tharo_1318 2c997c3766c41ff710e9361b17ba076b 772 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 14 767 32.587 T 14-10-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Tharo_1318 2c997c3766c41ff710e9361b17ba076b 772 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 676 720 9.5E-4 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Tharo_1318 2c997c3766c41ff710e9361b17ba076b 772 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 632 669 4.1 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Tharo_1318 2c997c3766c41ff710e9361b17ba076b 772 SUPERFAMILY SSF101904 535 762 1.44E-44 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal Tharo_1318 2c997c3766c41ff710e9361b17ba076b 772 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 42 497 6.5E-129 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Tharo_1318 2c997c3766c41ff710e9361b17ba076b 772 Gene3D G3DSA:3.90.199.10 42 518 9.4E-184 T 14-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 Tharo_1318 2c997c3766c41ff710e9361b17ba076b 772 Gene3D G3DSA:1.10.268.10 405 490 9.4E-184 T 14-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Tharo_1318 2c997c3766c41ff710e9361b17ba076b 772 SMART SM00434 21 497 4.2E-218 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Tharo_1785 9b69cc6a97ac56eea4eb860a6a5efe90 500 Gene3D G3DSA:3.40.50.1100 136 479 3.0E-135 T 14-10-2018 Tharo_1785 9b69cc6a97ac56eea4eb860a6a5efe90 500 TIGRFAM TIGR00260 thrC: threonine synthase 121 431 4.8E-68 T 14-10-2018 IPR004450 Threonine synthase-like Tharo_1785 9b69cc6a97ac56eea4eb860a6a5efe90 500 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 130 144 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 Tharo_1785 9b69cc6a97ac56eea4eb860a6a5efe90 500 Gene3D G3DSA:3.40.50.1100 128 466 3.0E-135 T 14-10-2018 Tharo_1785 9b69cc6a97ac56eea4eb860a6a5efe90 500 Gene3D G3DSA:3.90.1380.10 14 113 9.5E-34 T 14-10-2018 IPR037158 Threonine synthase, N-terminal domain superfamily Tharo_1785 9b69cc6a97ac56eea4eb860a6a5efe90 500 Pfam PF14821 Threonine synthase N terminus 18 98 5.4E-29 T 14-10-2018 IPR029144 Threonine synthase, N-terminal Tharo_1785 9b69cc6a97ac56eea4eb860a6a5efe90 500 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 130 438 6.8E-12 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Tharo_1785 9b69cc6a97ac56eea4eb860a6a5efe90 500 SUPERFAMILY SSF53686 17 497 2.4E-152 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Tharo_0698 4569830e397dbb99a06ba087c0245a69 134 TIGRFAM TIGR03751 conj_TIGR03751: conjugative transfer region lipoprotein, TIGR03751 family 2 130 8.3E-52 T 14-10-2018 IPR022262 Lipoprotein, putative Tharo_0284 5aabaede1f8a1afbe79b4938cc733039 143 TIGRFAM TIGR03757 conj_TIGR03757: integrating conjugative element protein, PFL_4709 family 31 139 1.0E-39 T 14-10-2018 IPR011090 Integrating conjugative element protein, PFL4709 Tharo_0284 5aabaede1f8a1afbe79b4938cc733039 143 Pfam PF07511 Protein of unknown function (DUF1525) 31 140 2.6E-36 T 14-10-2018 IPR011090 Integrating conjugative element protein, PFL4709 Tharo_1518 5d5266b4122bf25999e1f0af568ed793 619 PIRSF PIRSF031715 4 610 2.7E-209 T 14-10-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 Tharo_1518 5d5266b4122bf25999e1f0af568ed793 619 SMART SM00327 395 600 0.0017 T 14-10-2018 IPR002035 von Willebrand factor, type A Tharo_1518 5d5266b4122bf25999e1f0af568ed793 619 Pfam PF11775 Cobalamin biosynthesis protein CobT VWA domain 384 601 7.3E-93 T 14-10-2018 IPR025861 Cobalamin biosynthesis protein CobT VWA domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 Tharo_1518 5d5266b4122bf25999e1f0af568ed793 619 SUPERFAMILY SSF53300 397 592 5.24E-16 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Tharo_1518 5d5266b4122bf25999e1f0af568ed793 619 Gene3D G3DSA:3.40.50.410 395 597 6.3E-9 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Tharo_1518 5d5266b4122bf25999e1f0af568ed793 619 Pfam PF06213 Cobalamin biosynthesis protein CobT 17 242 2.7E-64 T 14-10-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 Tharo_3360 605e3109ee678a82919c85ee994dfe6d 220 Pfam PF00072 Response regulator receiver domain 3 113 5.3E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_3360 605e3109ee678a82919c85ee994dfe6d 220 SMART SM00448 1 112 6.1E-41 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_3360 605e3109ee678a82919c85ee994dfe6d 220 SMART SM00862 145 216 2.5E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_3360 605e3109ee678a82919c85ee994dfe6d 220 Gene3D G3DSA:1.10.10.10 120 217 3.2E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_3360 605e3109ee678a82919c85ee994dfe6d 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 4.7E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_3360 605e3109ee678a82919c85ee994dfe6d 220 Gene3D G3DSA:3.40.50.2300 1 119 1.0E-40 T 14-10-2018 Tharo_3360 605e3109ee678a82919c85ee994dfe6d 220 SUPERFAMILY SSF52172 1 180 8.97E-40 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_0474 29a8d134322c4fe7c37a6bfaac90b3bd 235 Gene3D G3DSA:3.20.20.10 1 232 6.1E-86 T 14-10-2018 IPR029066 PLP-binding barrel Tharo_0474 29a8d134322c4fe7c37a6bfaac90b3bd 235 PIRSF PIRSF004848 1 231 1.3E-70 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 Tharo_0474 29a8d134322c4fe7c37a6bfaac90b3bd 235 Pfam PF01168 Alanine racemase, N-terminal domain 8 227 3.1E-29 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Tharo_0474 29a8d134322c4fe7c37a6bfaac90b3bd 235 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 6 225 32.215 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 Tharo_0474 29a8d134322c4fe7c37a6bfaac90b3bd 235 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 1 226 2.3E-71 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 Tharo_0474 29a8d134322c4fe7c37a6bfaac90b3bd 235 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 76 90 - T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 Tharo_0474 29a8d134322c4fe7c37a6bfaac90b3bd 235 SUPERFAMILY SSF51419 1 224 3.4E-80 T 14-10-2018 IPR029066 PLP-binding barrel Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 SUPERFAMILY SSF47384 633 709 1.82E-7 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 SUPERFAMILY SSF55785 492 617 1.03E-12 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 Pfam PF00512 His Kinase A (phospho-acceptor) domain 642 708 3.2E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 Gene3D G3DSA:3.30.450.20 505 632 4.1E-11 T 14-10-2018 Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 Gene3D G3DSA:3.30.450.20 246 365 8.0E-23 T 14-10-2018 Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 Pfam PF13426 PAS domain 395 494 6.3E-12 T 14-10-2018 IPR000014 PAS domain Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 Gene3D G3DSA:3.30.450.20 379 504 8.7E-24 T 14-10-2018 Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 SMART SM01079 50 187 0.0095 T 14-10-2018 IPR006189 CHASE domain Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 Gene3D G3DSA:3.30.450.20 5 153 4.3E-5 T 14-10-2018 Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 SUPERFAMILY SSF55785 364 493 7.41E-25 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 PRINTS PR00344 Bacterial sensor protein C-terminal signature 813 823 2.0E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 PRINTS PR00344 Bacterial sensor protein C-terminal signature 848 861 2.0E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 PRINTS PR00344 Bacterial sensor protein C-terminal signature 824 842 2.0E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 PRINTS PR00344 Bacterial sensor protein C-terminal signature 795 809 2.0E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 SUPERFAMILY SSF55874 701 862 1.44E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 Gene3D G3DSA:1.10.287.130 646 708 2.1E-19 T 14-10-2018 Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 SMART SM00387 753 864 1.2E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 Pfam PF08447 PAS fold 282 352 1.3E-12 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 SMART SM00086 453 495 1.4E-5 T 14-10-2018 IPR001610 PAC motif Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 SMART SM00086 329 367 0.038 T 14-10-2018 IPR001610 PAC motif Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 SMART SM00086 579 619 150.0 T 14-10-2018 IPR001610 PAC motif Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 SMART SM00091 507 571 3.7 T 14-10-2018 IPR000014 PAS domain Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 SMART SM00091 258 324 2.5E-10 T 14-10-2018 IPR000014 PAS domain Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 SMART SM00091 379 446 8.5E-7 T 14-10-2018 IPR000014 PAS domain Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 Pfam PF13188 PAS domain 507 560 3.9E-6 T 14-10-2018 IPR000014 PAS domain Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 SUPERFAMILY SSF55785 263 368 1.61E-23 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 Gene3D G3DSA:3.30.565.10 710 871 7.9E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 506 624 1.1E-8 T 14-10-2018 IPR000014 PAS domain Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 257 374 2.1E-18 T 14-10-2018 IPR000014 PAS domain Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 377 502 2.3E-22 T 14-10-2018 IPR000014 PAS domain Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 SMART SM00388 641 711 5.1E-5 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_2626 45f5b89ff67e6b7a17b070c1d2c7873a 873 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 754 863 7.1E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1276 4da97e5f37cba3ecc5feeab025edc70d 347 Pfam PF01136 Peptidase family U32 89 329 3.7E-35 T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 Tharo_1868 e58848fc11dce543eccc5ad13eeb2599 910 Gene3D G3DSA:3.40.630.30 731 910 2.6E-42 T 14-10-2018 Tharo_1868 e58848fc11dce543eccc5ad13eeb2599 910 Gene3D G3DSA:3.40.50.261 135 299 1.8E-44 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_1868 e58848fc11dce543eccc5ad13eeb2599 910 Pfam PF00583 Acetyltransferase (GNAT) family 771 874 2.0E-8 T 14-10-2018 IPR000182 GNAT domain Tharo_1868 e58848fc11dce543eccc5ad13eeb2599 910 SMART SM00881 9 104 6.1E-30 T 14-10-2018 IPR003781 CoA-binding GO:0048037 Tharo_1868 e58848fc11dce543eccc5ad13eeb2599 910 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 156 297 1.4E-45 T 14-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain Tharo_1868 e58848fc11dce543eccc5ad13eeb2599 910 Gene3D G3DSA:3.30.470.20 496 707 2.7E-66 T 14-10-2018 Tharo_1868 e58848fc11dce543eccc5ad13eeb2599 910 SUPERFAMILY SSF51735 2 144 8.91E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1868 e58848fc11dce543eccc5ad13eeb2599 910 Gene3D G3DSA:3.40.50.261 303 466 1.1E-36 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_1868 e58848fc11dce543eccc5ad13eeb2599 910 SUPERFAMILY SSF55729 737 881 6.0E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Tharo_1868 e58848fc11dce543eccc5ad13eeb2599 910 Pfam PF13380 CoA binding domain 13 139 1.8E-21 T 14-10-2018 IPR003781 CoA-binding GO:0048037 Tharo_1868 e58848fc11dce543eccc5ad13eeb2599 910 Gene3D G3DSA:3.40.50.720 5 133 5.7E-35 T 14-10-2018 Tharo_1868 e58848fc11dce543eccc5ad13eeb2599 910 Pfam PF13549 ATP-grasp domain 488 709 1.2E-74 T 14-10-2018 Tharo_1868 e58848fc11dce543eccc5ad13eeb2599 910 SUPERFAMILY SSF56059 495 710 7.39E-34 T 14-10-2018 Tharo_1868 e58848fc11dce543eccc5ad13eeb2599 910 Gene3D G3DSA:3.30.1490.20 514 591 2.7E-66 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Tharo_1868 e58848fc11dce543eccc5ad13eeb2599 910 SUPERFAMILY SSF52210 305 457 5.49E-28 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_1868 e58848fc11dce543eccc5ad13eeb2599 910 SUPERFAMILY SSF52210 136 300 5.36E-35 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_0640 651125c13bcdf9d4a027a75284c97180 252 SUPERFAMILY SSF51366 1 251 2.35E-87 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Tharo_0640 651125c13bcdf9d4a027a75284c97180 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 251 3.2E-117 T 14-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 Tharo_0640 651125c13bcdf9d4a027a75284c97180 252 Pfam PF00977 Histidine biosynthesis protein 5 234 2.4E-92 T 14-10-2018 IPR006062 Histidine biosynthesis GO:0000105 Tharo_0640 651125c13bcdf9d4a027a75284c97180 252 Gene3D G3DSA:3.20.20.70 1 252 1.5E-112 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_0640 651125c13bcdf9d4a027a75284c97180 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 251 49.681 T 14-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 Tharo_0199 280601aecece27d80f189b765595b79e 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 56 9.9E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0199 280601aecece27d80f189b765595b79e 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 46 9.9E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0199 280601aecece27d80f189b765595b79e 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 56 67 9.9E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0199 280601aecece27d80f189b765595b79e 316 Gene3D G3DSA:3.40.190.10 182 281 3.7E-54 T 14-10-2018 Tharo_0199 280601aecece27d80f189b765595b79e 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 20 78 1.6E-14 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0199 280601aecece27d80f189b765595b79e 316 SUPERFAMILY SSF46785 13 97 4.84E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0199 280601aecece27d80f189b765595b79e 316 SUPERFAMILY SSF53850 102 309 1.56E-40 T 14-10-2018 Tharo_0199 280601aecece27d80f189b765595b79e 316 Pfam PF03466 LysR substrate binding domain 107 308 9.4E-14 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_0199 280601aecece27d80f189b765595b79e 316 Gene3D G3DSA:1.10.10.10 11 99 1.7E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0199 280601aecece27d80f189b765595b79e 316 Gene3D G3DSA:3.40.190.10 102 305 3.7E-54 T 14-10-2018 Tharo_0308 01dacbcc301b004b137403616bab128f 73 Pfam PF11190 Protein of unknown function (DUF2976) 1 72 6.4E-26 T 14-10-2018 IPR021356 Integrating conjugative element protein PFL4702 Tharo_0308 01dacbcc301b004b137403616bab128f 73 TIGRFAM TIGR03745 conj_TIGR03745: integrating conjugative element membrane protein, PFL_4702 family 1 73 1.3E-33 T 14-10-2018 IPR021356 Integrating conjugative element protein PFL4702 Tharo_1929 33ac3964f6a00ec0563bcfbe58a32db0 542 Gene3D G3DSA:3.40.50.620 264 542 2.0E-115 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_1929 33ac3964f6a00ec0563bcfbe58a32db0 542 SUPERFAMILY SSF52402 254 524 5.59E-76 T 14-10-2018 Tharo_1929 33ac3964f6a00ec0563bcfbe58a32db0 542 TIGRFAM TIGR00552 nadE: NAD+ synthetase 266 517 6.4E-57 T 14-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 Tharo_1929 33ac3964f6a00ec0563bcfbe58a32db0 542 Pfam PF00795 Carbon-nitrogen hydrolase 10 240 2.9E-27 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 Tharo_1929 33ac3964f6a00ec0563bcfbe58a32db0 542 Pfam PF02540 NAD synthase 267 514 5.5E-71 T 14-10-2018 IPR022310 NAD/GMP synthase Tharo_1929 33ac3964f6a00ec0563bcfbe58a32db0 542 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 9 540 29.152 T 14-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 Tharo_1929 33ac3964f6a00ec0563bcfbe58a32db0 542 Gene3D G3DSA:3.60.110.10 4 258 1.6E-89 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Tharo_1929 33ac3964f6a00ec0563bcfbe58a32db0 542 SUPERFAMILY SSF56317 7 243 1.83E-64 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Tharo_1929 33ac3964f6a00ec0563bcfbe58a32db0 542 PIRSF PIRSF006630 248 542 1.1E-115 T 14-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 Tharo_1929 33ac3964f6a00ec0563bcfbe58a32db0 542 PIRSF PIRSF006630 6 260 3.1E-77 T 14-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 Tharo_3384 d3b99404f9edb67374183e0dd85888e4 738 Pfam PF00271 Helicase conserved C-terminal domain 513 596 2.0E-4 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_3384 d3b99404f9edb67374183e0dd85888e4 738 Gene3D G3DSA:3.40.50.300 194 387 3.3E-70 T 14-10-2018 Tharo_3384 d3b99404f9edb67374183e0dd85888e4 738 SMART SM00490 500 597 7.3E-5 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_3384 d3b99404f9edb67374183e0dd85888e4 738 SMART SM00487 202 388 1.1E-15 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Tharo_3384 d3b99404f9edb67374183e0dd85888e4 738 TIGRFAM TIGR00595 priA: primosomal protein N' 228 736 8.0E-173 T 14-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 Tharo_3384 d3b99404f9edb67374183e0dd85888e4 738 SUPERFAMILY SSF52540 204 377 6.24E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3384 d3b99404f9edb67374183e0dd85888e4 738 SUPERFAMILY SSF52540 227 630 1.49E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3384 d3b99404f9edb67374183e0dd85888e4 738 Hamap MF_00983 Probable primosomal protein N' [priA]. 19 738 23.692 T 14-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 Tharo_3384 d3b99404f9edb67374183e0dd85888e4 738 Pfam PF00270 DEAD/DEAH box helicase 207 368 2.1E-12 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Tharo_3384 d3b99404f9edb67374183e0dd85888e4 738 Gene3D G3DSA:1.10.8.630 15 123 1.5E-29 T 14-10-2018 Tharo_3187 ffcef0efd662fd4bd9db0613111ce0ef 318 Hamap MF_00301 Homoserine kinase [thrB]. 1 318 146.558 T 14-10-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 Tharo_3187 ffcef0efd662fd4bd9db0613111ce0ef 318 Gene3D G3DSA:3.30.200.20 1 102 9.7E-34 T 14-10-2018 Tharo_3187 ffcef0efd662fd4bd9db0613111ce0ef 318 Gene3D G3DSA:3.90.1200.10 105 313 5.4E-67 T 14-10-2018 Tharo_3187 ffcef0efd662fd4bd9db0613111ce0ef 318 SUPERFAMILY SSF56112 5 311 1.75E-68 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Tharo_3187 ffcef0efd662fd4bd9db0613111ce0ef 318 Pfam PF01636 Phosphotransferase enzyme family 28 257 2.0E-30 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase Tharo_3187 ffcef0efd662fd4bd9db0613111ce0ef 318 TIGRFAM TIGR00938 thrB_alt: homoserine kinase 1 307 9.4E-101 T 14-10-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 Tharo_2034 322617a5690523eedf667512bbb714bf 388 Pfam PF00246 Zinc carboxypeptidase 129 346 2.0E-22 T 14-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 Tharo_2034 322617a5690523eedf667512bbb714bf 388 SUPERFAMILY SSF53187 105 348 3.49E-57 T 14-10-2018 Tharo_2034 322617a5690523eedf667512bbb714bf 388 Gene3D G3DSA:2.60.40.3120 1 113 9.6E-43 T 14-10-2018 Tharo_2034 322617a5690523eedf667512bbb714bf 388 SMART SM00631 113 353 0.0013 T 14-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 Tharo_2034 322617a5690523eedf667512bbb714bf 388 Gene3D G3DSA:3.40.630.10 114 373 6.8E-64 T 14-10-2018 Tharo_1682 1feefb1bef4853ab1c8c51488b0829bc 311 SUPERFAMILY SSF103481 221 304 1.7E-8 T 14-10-2018 Tharo_1682 1feefb1bef4853ab1c8c51488b0829bc 311 SUPERFAMILY SSF103481 41 145 9.81E-13 T 14-10-2018 Tharo_1682 1feefb1bef4853ab1c8c51488b0829bc 311 Pfam PF00892 EamA-like transporter family 158 302 3.8E-9 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Tharo_1682 1feefb1bef4853ab1c8c51488b0829bc 311 Pfam PF00892 EamA-like transporter family 9 142 3.6E-24 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Tharo_3272 f7d590da22ae58d9dd7a4162aa0edfea 124 Pfam PF03091 CutA1 divalent ion tolerance protein 11 107 9.3E-35 T 14-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 Tharo_3272 f7d590da22ae58d9dd7a4162aa0edfea 124 Gene3D G3DSA:3.30.70.120 3 110 4.3E-38 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Tharo_3272 f7d590da22ae58d9dd7a4162aa0edfea 124 SUPERFAMILY SSF54913 8 108 1.15E-36 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta Tharo_0051 90d1bc819cde9fee0daa63311699c7b6 658 Gene3D G3DSA:3.80.30.20 381 564 1.7E-12 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Tharo_0051 90d1bc819cde9fee0daa63311699c7b6 658 SMART SM00729 383 596 2.5E-14 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Tharo_0051 90d1bc819cde9fee0daa63311699c7b6 658 SUPERFAMILY SSF102114 362 551 2.35E-24 T 14-10-2018 Tharo_0051 90d1bc819cde9fee0daa63311699c7b6 658 Pfam PF02310 B12 binding domain 231 309 8.2E-7 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 Tharo_0051 90d1bc819cde9fee0daa63311699c7b6 658 Pfam PF04055 Radical SAM superfamily 386 547 1.5E-9 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_0436 17e0fc29c60d98603d342e01aa0a4678 295 Pfam PF00892 EamA-like transporter family 165 291 1.1E-9 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Tharo_0436 17e0fc29c60d98603d342e01aa0a4678 295 Pfam PF00892 EamA-like transporter family 15 143 1.5E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Tharo_0436 17e0fc29c60d98603d342e01aa0a4678 295 SUPERFAMILY SSF103481 201 292 1.03E-12 T 14-10-2018 Tharo_0436 17e0fc29c60d98603d342e01aa0a4678 295 SUPERFAMILY SSF103481 46 145 6.41E-14 T 14-10-2018 Tharo_3470 b9995c2282b2422af7ef67fac7af8e5d 144 Pfam PF03230 Antirestriction protein 51 144 1.1E-32 T 14-10-2018 IPR004914 Antirestriction protein Tharo_3470 b9995c2282b2422af7ef67fac7af8e5d 144 ProDom PD012854 PLASMID KLCA ANTIRESTRICTION YFJX YCIB ARDB STABLE YFEB Z1216 C0275 52 144 3.0E-36 T 14-10-2018 IPR004914 Antirestriction protein Tharo_3470 b9995c2282b2422af7ef67fac7af8e5d 144 Gene3D G3DSA:1.10.472.120 4 144 3.5E-57 T 14-10-2018 Tharo_0291 88b75b87e0c6b29890286606e3b72f1a 303 Pfam PF08281 Sigma-70, region 4 112 161 1.2E-10 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Tharo_0291 88b75b87e0c6b29890286606e3b72f1a 303 Pfam PF04542 Sigma-70 region 2 6 69 1.4E-16 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Tharo_0291 88b75b87e0c6b29890286606e3b72f1a 303 SUPERFAMILY SSF88946 6 84 7.06E-14 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Tharo_0291 88b75b87e0c6b29890286606e3b72f1a 303 Gene3D G3DSA:3.10.450.50 173 293 1.2E-8 T 14-10-2018 Tharo_0291 88b75b87e0c6b29890286606e3b72f1a 303 Gene3D G3DSA:1.10.1740.10 4 78 4.6E-9 T 14-10-2018 Tharo_0291 88b75b87e0c6b29890286606e3b72f1a 303 SUPERFAMILY SSF88659 106 162 5.98E-10 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Tharo_0291 88b75b87e0c6b29890286606e3b72f1a 303 Gene3D G3DSA:1.10.10.10 94 165 3.3E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0291 88b75b87e0c6b29890286606e3b72f1a 303 SUPERFAMILY SSF54427 177 298 1.92E-13 T 14-10-2018 IPR032710 NTF2-like domain superfamily Tharo_0291 88b75b87e0c6b29890286606e3b72f1a 303 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 163 3.4E-16 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Tharo_1456 fe7805c021f22673caa3943bdb67c568 314 Gene3D G3DSA:3.40.50.300 72 243 4.4E-37 T 14-10-2018 Tharo_1456 fe7805c021f22673caa3943bdb67c568 314 Gene3D G3DSA:1.10.40.50 244 312 5.3E-21 T 14-10-2018 Tharo_1456 fe7805c021f22673caa3943bdb67c568 314 Pfam PF03193 RsgA GTPase 69 243 1.1E-44 T 14-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 Tharo_1456 fe7805c021f22673caa3943bdb67c568 314 SUPERFAMILY SSF52540 84 306 6.28E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1456 fe7805c021f22673caa3943bdb67c568 314 Gene3D G3DSA:2.40.50.140 13 69 8.7E-6 T 14-10-2018 Tharo_1456 fe7805c021f22673caa3943bdb67c568 314 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 49 299 2.0E-57 T 14-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 Tharo_1456 fe7805c021f22673caa3943bdb67c568 314 SUPERFAMILY SSF50249 15 72 7.02E-5 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_1456 fe7805c021f22673caa3943bdb67c568 314 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 15 308 32.668 T 14-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 Tharo_0430 905dc5ca293913117bf2c9a9860f934f 319 Pfam PF00589 Phage integrase family 130 306 1.5E-17 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Tharo_0430 905dc5ca293913117bf2c9a9860f934f 319 Gene3D G3DSA:1.10.150.130 19 120 5.7E-28 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Tharo_0430 905dc5ca293913117bf2c9a9860f934f 319 SUPERFAMILY SSF56349 121 313 6.77E-44 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Tharo_0430 905dc5ca293913117bf2c9a9860f934f 319 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 28 95 9.3E-7 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 Tharo_0430 905dc5ca293913117bf2c9a9860f934f 319 Gene3D G3DSA:1.10.443.10 123 309 3.6E-49 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Tharo_0430 905dc5ca293913117bf2c9a9860f934f 319 SUPERFAMILY SSF47823 24 122 5.49E-28 T 14-10-2018 Tharo_1894 e1cc6da24b9268aa8c0a9481d77d6090 158 SUPERFAMILY SSF54534 83 157 3.27E-23 T 14-10-2018 Tharo_1894 e1cc6da24b9268aa8c0a9481d77d6090 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 Tharo_1894 e1cc6da24b9268aa8c0a9481d77d6090 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 121 137 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 Tharo_1894 e1cc6da24b9268aa8c0a9481d77d6090 158 Pfam PF03449 Transcription elongation factor, N-terminal 5 74 1.8E-31 T 14-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 Tharo_1894 e1cc6da24b9268aa8c0a9481d77d6090 158 SUPERFAMILY SSF46557 3 77 1.02E-27 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 Tharo_1894 e1cc6da24b9268aa8c0a9481d77d6090 158 Gene3D G3DSA:3.10.50.30 78 158 2.1E-28 T 14-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 Tharo_1894 e1cc6da24b9268aa8c0a9481d77d6090 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 155 1.0E-55 T 14-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 Tharo_1894 e1cc6da24b9268aa8c0a9481d77d6090 158 PIRSF PIRSF006092 1 158 1.0E-51 T 14-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 Tharo_1894 e1cc6da24b9268aa8c0a9481d77d6090 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 156 32.829 T 14-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 Tharo_1894 e1cc6da24b9268aa8c0a9481d77d6090 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 84 157 2.1E-27 T 14-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 Tharo_1894 e1cc6da24b9268aa8c0a9481d77d6090 158 Gene3D G3DSA:1.10.287.180 1 75 3.9E-31 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 Tharo_3321 b9acf8b047dc94796b5d151b6de74584 407 Pfam PF04055 Radical SAM superfamily 37 203 1.4E-16 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_3321 b9acf8b047dc94796b5d151b6de74584 407 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 34 384 4.2E-106 T 14-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 Tharo_3321 b9acf8b047dc94796b5d151b6de74584 407 Gene3D G3DSA:3.80.30.20 16 326 8.5E-96 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Tharo_3321 b9acf8b047dc94796b5d151b6de74584 407 SUPERFAMILY SSF102114 23 405 1.57E-110 T 14-10-2018 Tharo_3321 b9acf8b047dc94796b5d151b6de74584 407 Pfam PF06969 HemN C-terminal domain 332 394 2.1E-14 T 14-10-2018 IPR010723 HemN, C-terminal Tharo_3321 b9acf8b047dc94796b5d151b6de74584 407 SMART SM00729 32 249 1.7E-51 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Tharo_1556 51df9b90f893ee78a9f45b9635866567 482 Gene3D G3DSA:1.10.40.30 378 457 1.1E-184 T 14-10-2018 Tharo_1556 51df9b90f893ee78a9f45b9635866567 482 Gene3D G3DSA:1.20.200.10 137 473 1.1E-184 T 14-10-2018 Tharo_1556 51df9b90f893ee78a9f45b9635866567 482 SUPERFAMILY SSF48557 22 477 8.8E-147 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 Tharo_1556 51df9b90f893ee78a9f45b9635866567 482 TIGRFAM TIGR00838 argH: argininosuccinate lyase 22 478 6.9E-180 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Tharo_1556 51df9b90f893ee78a9f45b9635866567 482 Gene3D G3DSA:1.10.275.10 43 247 1.1E-184 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal Tharo_1556 51df9b90f893ee78a9f45b9635866567 482 Pfam PF14698 Argininosuccinate lyase C-terminal 381 455 5.2E-20 T 14-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Tharo_1556 51df9b90f893ee78a9f45b9635866567 482 PRINTS PR00149 Fumarate lyase superfamily signature 249 276 2.3E-30 T 14-10-2018 IPR000362 Fumarate lyase family Tharo_1556 51df9b90f893ee78a9f45b9635866567 482 PRINTS PR00149 Fumarate lyase superfamily signature 120 138 2.3E-30 T 14-10-2018 IPR000362 Fumarate lyase family Tharo_1556 51df9b90f893ee78a9f45b9635866567 482 PRINTS PR00149 Fumarate lyase superfamily signature 165 183 2.3E-30 T 14-10-2018 IPR000362 Fumarate lyase family Tharo_1556 51df9b90f893ee78a9f45b9635866567 482 PRINTS PR00149 Fumarate lyase superfamily signature 293 309 2.3E-30 T 14-10-2018 IPR000362 Fumarate lyase family Tharo_1556 51df9b90f893ee78a9f45b9635866567 482 PRINTS PR00145 Argininosuccinate lyase family signature 119 141 4.1E-68 T 14-10-2018 Tharo_1556 51df9b90f893ee78a9f45b9635866567 482 PRINTS PR00145 Argininosuccinate lyase family signature 249 273 4.1E-68 T 14-10-2018 Tharo_1556 51df9b90f893ee78a9f45b9635866567 482 PRINTS PR00145 Argininosuccinate lyase family signature 160 180 4.1E-68 T 14-10-2018 Tharo_1556 51df9b90f893ee78a9f45b9635866567 482 PRINTS PR00145 Argininosuccinate lyase family signature 211 227 4.1E-68 T 14-10-2018 Tharo_1556 51df9b90f893ee78a9f45b9635866567 482 PRINTS PR00145 Argininosuccinate lyase family signature 293 309 4.1E-68 T 14-10-2018 Tharo_1556 51df9b90f893ee78a9f45b9635866567 482 PRINTS PR00145 Argininosuccinate lyase family signature 328 347 4.1E-68 T 14-10-2018 Tharo_1556 51df9b90f893ee78a9f45b9635866567 482 ProSitePatterns PS00163 Fumarate lyases signature. 293 302 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 Tharo_1556 51df9b90f893ee78a9f45b9635866567 482 Pfam PF00206 Lyase 24 318 6.6E-77 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal Tharo_1556 51df9b90f893ee78a9f45b9635866567 482 Hamap MF_00006 Argininosuccinate lyase [argH]. 20 478 42.935 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Tharo_1177 dd338a188c182ef7528e7e137b686a71 376 Pfam PF01264 Chorismate synthase 10 345 1.0E-134 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Tharo_1177 dd338a188c182ef7528e7e137b686a71 376 SUPERFAMILY SSF103263 4 352 1.44E-144 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Tharo_1177 dd338a188c182ef7528e7e137b686a71 376 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Tharo_1177 dd338a188c182ef7528e7e137b686a71 376 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Tharo_1177 dd338a188c182ef7528e7e137b686a71 376 TIGRFAM TIGR00033 aroC: chorismate synthase 10 350 2.9E-135 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Tharo_1177 dd338a188c182ef7528e7e137b686a71 376 Gene3D G3DSA:3.60.150.10 1 363 9.8E-148 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Tharo_1177 dd338a188c182ef7528e7e137b686a71 376 Hamap MF_00300 Chorismate synthase [aroC]. 10 354 35.977 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Tharo_1177 dd338a188c182ef7528e7e137b686a71 376 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Tharo_1177 dd338a188c182ef7528e7e137b686a71 376 PIRSF PIRSF001456 3 363 8.9E-132 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Tharo_2245 d8d80249183846321c789b0180398b9d 570 Gene3D G3DSA:3.30.450.90 163 288 3.7E-46 T 14-10-2018 Tharo_2245 d8d80249183846321c789b0180398b9d 570 Gene3D G3DSA:3.40.50.300 290 570 4.0E-110 T 14-10-2018 Tharo_2245 d8d80249183846321c789b0180398b9d 570 SMART SM00382 316 439 7.4E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2245 d8d80249183846321c789b0180398b9d 570 SUPERFAMILY SSF52540 172 564 2.58E-98 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2245 d8d80249183846321c789b0180398b9d 570 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 45 150 2.6E-16 T 14-10-2018 IPR007831 General secretory system II, protein E, N-terminal Tharo_2245 d8d80249183846321c789b0180398b9d 570 Pfam PF00437 Type II/IV secretion system protein 196 455 7.8E-83 T 14-10-2018 IPR001482 Type II/IV secretion system protein Tharo_2245 d8d80249183846321c789b0180398b9d 570 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 383 397 - T 14-10-2018 IPR001482 Type II/IV secretion system protein Tharo_2245 d8d80249183846321c789b0180398b9d 570 Gene3D G3DSA:3.30.300.160 66 147 1.0E-12 T 14-10-2018 Tharo_2245 d8d80249183846321c789b0180398b9d 570 SUPERFAMILY SSF160246 9 146 1.52E-29 T 14-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily Tharo_1793 13588110f9ae0a79d3bc9896bb9abacd 910 Pfam PF00583 Acetyltransferase (GNAT) family 801 890 1.6E-8 T 14-10-2018 IPR000182 GNAT domain Tharo_1793 13588110f9ae0a79d3bc9896bb9abacd 910 Gene3D G3DSA:3.40.50.261 313 479 4.9E-57 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_1793 13588110f9ae0a79d3bc9896bb9abacd 910 Gene3D G3DSA:3.40.630.30 744 906 3.7E-43 T 14-10-2018 Tharo_1793 13588110f9ae0a79d3bc9896bb9abacd 910 Gene3D G3DSA:3.40.50.720 20 149 3.5E-38 T 14-10-2018 Tharo_1793 13588110f9ae0a79d3bc9896bb9abacd 910 SUPERFAMILY SSF52210 314 471 1.27E-45 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_1793 13588110f9ae0a79d3bc9896bb9abacd 910 Gene3D G3DSA:3.30.470.20 506 717 8.5E-73 T 14-10-2018 Tharo_1793 13588110f9ae0a79d3bc9896bb9abacd 910 Pfam PF13549 ATP-grasp domain 498 719 1.8E-77 T 14-10-2018 Tharo_1793 13588110f9ae0a79d3bc9896bb9abacd 910 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 171 308 1.4E-53 T 14-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain Tharo_1793 13588110f9ae0a79d3bc9896bb9abacd 910 SUPERFAMILY SSF55729 751 895 7.03E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Tharo_1793 13588110f9ae0a79d3bc9896bb9abacd 910 SUPERFAMILY SSF56059 506 721 7.51E-40 T 14-10-2018 Tharo_1793 13588110f9ae0a79d3bc9896bb9abacd 910 Gene3D G3DSA:3.30.1490.20 524 601 8.5E-73 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Tharo_1793 13588110f9ae0a79d3bc9896bb9abacd 910 SMART SM00881 25 120 9.9E-29 T 14-10-2018 IPR003781 CoA-binding GO:0048037 Tharo_1793 13588110f9ae0a79d3bc9896bb9abacd 910 SUPERFAMILY SSF52210 149 315 2.09E-45 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_1793 13588110f9ae0a79d3bc9896bb9abacd 910 SUPERFAMILY SSF51735 14 159 6.08E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1793 13588110f9ae0a79d3bc9896bb9abacd 910 Gene3D G3DSA:3.40.50.261 150 309 5.9E-56 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_1793 13588110f9ae0a79d3bc9896bb9abacd 910 Pfam PF13380 CoA binding domain 29 154 1.2E-19 T 14-10-2018 IPR003781 CoA-binding GO:0048037 Tharo_2508 1b8758aabbf38c11de163b69f6a16575 511 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Tharo_2508 1b8758aabbf38c11de163b69f6a16575 511 Gene3D G3DSA:3.20.20.70 3 276 9.2E-110 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_2508 1b8758aabbf38c11de163b69f6a16575 511 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 199 212 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Tharo_2508 1b8758aabbf38c11de163b69f6a16575 511 Gene3D G3DSA:3.30.160.270 394 501 9.9E-13 T 14-10-2018 Tharo_2508 1b8758aabbf38c11de163b69f6a16575 511 Pfam PF00682 HMGL-like 6 273 2.1E-98 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Tharo_2508 1b8758aabbf38c11de163b69f6a16575 511 SUPERFAMILY SSF51569 1 291 4.03E-101 T 14-10-2018 Tharo_2508 1b8758aabbf38c11de163b69f6a16575 511 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 6 498 1.4E-219 T 14-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Tharo_2508 1b8758aabbf38c11de163b69f6a16575 511 SMART SM00917 370 501 2.1E-42 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Tharo_2508 1b8758aabbf38c11de163b69f6a16575 511 SUPERFAMILY SSF110921 392 500 2.22E-25 T 14-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Tharo_2508 1b8758aabbf38c11de163b69f6a16575 511 Gene3D G3DSA:1.10.238.260 280 393 6.5E-36 T 14-10-2018 Tharo_2508 1b8758aabbf38c11de163b69f6a16575 511 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 2 510 43.733 T 14-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Tharo_2508 1b8758aabbf38c11de163b69f6a16575 511 Pfam PF08502 LeuA allosteric (dimerisation) domain 370 500 1.2E-36 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Tharo_2899 cec18b7aaaad703fa316ba9013e8f790 296 SUPERFAMILY SSF53474 59 296 1.41E-46 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_2899 cec18b7aaaad703fa316ba9013e8f790 296 Pfam PF01738 Dienelactone hydrolase family 72 294 2.3E-63 T 14-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 Tharo_2899 cec18b7aaaad703fa316ba9013e8f790 296 Gene3D G3DSA:3.40.50.1820 54 293 9.8E-64 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 34 692 4.7E-241 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 Gene3D G3DSA:2.40.50.140 345 416 7.8E-35 T 14-10-2018 Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 Hamap MF_01588 DNA ligase [ligA]. 25 697 53.977 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 Gene3D G3DSA:1.10.287.610 23 93 6.3E-29 T 14-10-2018 Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 437 464 9.4E-11 T 14-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 SUPERFAMILY SSF47781 437 614 3.11E-62 T 14-10-2018 IPR010994 RuvA domain 2-like Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 PIRSF PIRSF001604 20 702 8.2E-231 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 Gene3D G3DSA:1.10.150.20 462 535 4.5E-30 T 14-10-2018 Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 27 345 2.5E-109 T 14-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 349 424 1.9E-35 T 14-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 Gene3D G3DSA:3.40.50.10190 621 702 1.9E-25 T 14-10-2018 IPR036420 BRCT domain superfamily Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 SUPERFAMILY SSF52113 624 697 2.62E-18 T 14-10-2018 IPR036420 BRCT domain superfamily Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 SMART SM00532 26 478 2.1E-235 T 14-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 358 373 - T 14-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 Gene3D G3DSA:2.20.70.80 418 461 3.1E-12 T 14-10-2018 Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 143 172 - T 14-10-2018 IPR018239 NAD-dependent DNA ligase, active site Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 Gene3D G3DSA:3.30.470.90 94 344 6.1E-87 T 14-10-2018 Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 SMART SM00292 623 700 3.5E-14 T 14-10-2018 IPR001357 BRCT domain Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 Pfam PF12826 Helix-hairpin-helix motif 540 603 1.1E-25 T 14-10-2018 Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 SUPERFAMILY SSF56091 25 343 2.88E-107 T 14-10-2018 Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 Pfam PF14520 Helix-hairpin-helix domain 478 530 5.9E-6 T 14-10-2018 Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 Gene3D G3DSA:1.10.150.20 536 616 1.5E-32 T 14-10-2018 Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 SMART SM00278 510 529 0.93 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 SMART SM00278 476 495 19.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 SMART SM00278 574 593 4.8 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 SMART SM00278 542 561 240.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 626 694 5.9E-13 T 14-10-2018 IPR001357 BRCT domain Tharo_2073 65e0f7ca1da72e497505011ce537de53 704 SUPERFAMILY SSF50249 345 425 1.44E-28 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_2517 42f3a4c06e2717ade33dda4b397cb30b 501 PRINTS PR00481 Cytosol aminopeptidase signature 286 307 2.3E-55 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Tharo_2517 42f3a4c06e2717ade33dda4b397cb30b 501 PRINTS PR00481 Cytosol aminopeptidase signature 373 388 2.3E-55 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Tharo_2517 42f3a4c06e2717ade33dda4b397cb30b 501 PRINTS PR00481 Cytosol aminopeptidase signature 264 281 2.3E-55 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Tharo_2517 42f3a4c06e2717ade33dda4b397cb30b 501 PRINTS PR00481 Cytosol aminopeptidase signature 345 365 2.3E-55 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Tharo_2517 42f3a4c06e2717ade33dda4b397cb30b 501 PRINTS PR00481 Cytosol aminopeptidase signature 323 344 2.3E-55 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Tharo_2517 42f3a4c06e2717ade33dda4b397cb30b 501 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 188 488 1.4E-127 T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 Tharo_2517 42f3a4c06e2717ade33dda4b397cb30b 501 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 3 497 38.832 T 14-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 Tharo_2517 42f3a4c06e2717ade33dda4b397cb30b 501 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 19 147 4.8E-31 T 14-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 Tharo_2517 42f3a4c06e2717ade33dda4b397cb30b 501 SUPERFAMILY SSF52949 1 186 3.18E-40 T 14-10-2018 Tharo_2517 42f3a4c06e2717ade33dda4b397cb30b 501 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 349 356 - T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 Tharo_2517 42f3a4c06e2717ade33dda4b397cb30b 501 SUPERFAMILY SSF53187 182 494 3.01E-125 T 14-10-2018 Tharo_2517 42f3a4c06e2717ade33dda4b397cb30b 501 Gene3D G3DSA:3.40.630.10 183 497 1.1E-139 T 14-10-2018 Tharo_2517 42f3a4c06e2717ade33dda4b397cb30b 501 Gene3D G3DSA:3.40.220.10 1 164 1.3E-50 T 14-10-2018 Tharo_1471 18f4a74b3097c544d8823eb81834fc01 899 Gene3D G3DSA:3.30.499.20 4 370 4.5E-153 T 14-10-2018 Tharo_1471 18f4a74b3097c544d8823eb81834fc01 899 Pfam PF00694 Aconitase C-terminal domain 695 824 1.5E-38 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 Tharo_1471 18f4a74b3097c544d8823eb81834fc01 899 SUPERFAMILY SSF52016 637 896 2.35E-77 T 14-10-2018 Tharo_1471 18f4a74b3097c544d8823eb81834fc01 899 SUPERFAMILY SSF53732 22 627 6.28E-209 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 Tharo_1471 18f4a74b3097c544d8823eb81834fc01 899 ProSitePatterns PS00450 Aconitase family signature 1. 429 445 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Tharo_1471 18f4a74b3097c544d8823eb81834fc01 899 Pfam PF00330 Aconitase family (aconitate hydratase) 75 564 4.9E-172 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Tharo_1471 18f4a74b3097c544d8823eb81834fc01 899 PRINTS PR00415 Aconitase family signature 171 179 3.2E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Tharo_1471 18f4a74b3097c544d8823eb81834fc01 899 PRINTS PR00415 Aconitase family signature 214 229 3.2E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Tharo_1471 18f4a74b3097c544d8823eb81834fc01 899 PRINTS PR00415 Aconitase family signature 147 160 3.2E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Tharo_1471 18f4a74b3097c544d8823eb81834fc01 899 PRINTS PR00415 Aconitase family signature 276 289 3.2E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Tharo_1471 18f4a74b3097c544d8823eb81834fc01 899 PRINTS PR00415 Aconitase family signature 370 384 3.2E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Tharo_1471 18f4a74b3097c544d8823eb81834fc01 899 PRINTS PR00415 Aconitase family signature 290 303 3.2E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Tharo_1471 18f4a74b3097c544d8823eb81834fc01 899 PRINTS PR00415 Aconitase family signature 433 444 3.2E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Tharo_1471 18f4a74b3097c544d8823eb81834fc01 899 PRINTS PR00415 Aconitase family signature 200 213 3.2E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Tharo_1471 18f4a74b3097c544d8823eb81834fc01 899 PRINTS PR00415 Aconitase family signature 495 508 3.2E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Tharo_1471 18f4a74b3097c544d8823eb81834fc01 899 Gene3D G3DSA:3.30.499.10 371 592 7.3E-95 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 Tharo_1471 18f4a74b3097c544d8823eb81834fc01 899 Gene3D G3DSA:3.20.19.10 656 897 3.3E-98 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 Tharo_1471 18f4a74b3097c544d8823eb81834fc01 899 ProSitePatterns PS01244 Aconitase family signature 2. 495 508 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Tharo_1471 18f4a74b3097c544d8823eb81834fc01 899 Gene3D G3DSA:1.10.1440.20 593 652 8.2E-12 T 14-10-2018 Tharo_1471 18f4a74b3097c544d8823eb81834fc01 899 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 21 897 0.0 T 14-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 Tharo_1326 e2e668289a8c217a630cc20d70c5ed6d 545 TIGRFAM TIGR00337 PyrG: CTP synthase 1 536 2.9E-248 T 14-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 Tharo_1326 e2e668289a8c217a630cc20d70c5ed6d 545 Pfam PF00117 Glutamine amidotransferase class-I 300 535 1.1E-54 T 14-10-2018 IPR017926 Glutamine amidotransferase Tharo_1326 e2e668289a8c217a630cc20d70c5ed6d 545 SUPERFAMILY SSF52317 287 542 2.01E-81 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Tharo_1326 e2e668289a8c217a630cc20d70c5ed6d 545 SUPERFAMILY SSF52540 1 266 1.55E-122 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1326 e2e668289a8c217a630cc20d70c5ed6d 545 Pfam PF06418 CTP synthase N-terminus 3 265 4.6E-127 T 14-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 Tharo_1326 e2e668289a8c217a630cc20d70c5ed6d 545 Hamap MF_01227 CTP synthase [pyrG]. 2 541 51.26 T 14-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 Tharo_1326 e2e668289a8c217a630cc20d70c5ed6d 545 Gene3D G3DSA:3.40.50.300 1 283 1.2E-131 T 14-10-2018 Tharo_1326 e2e668289a8c217a630cc20d70c5ed6d 545 Gene3D G3DSA:3.40.50.880 285 545 2.8E-99 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Tharo_2194 ea249688218e565d581c1f360fa439ad 143 Gene3D G3DSA:3.30.420.270 61 136 3.9E-6 T 14-10-2018 Tharo_2194 ea249688218e565d581c1f360fa439ad 143 Pfam PF02472 Biopolymer transport protein ExbD/TolR 10 139 3.6E-26 T 14-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 Tharo_2287 009aa95293241847fddb2ccec4e02454 242 SMART SM00419 179 227 4.6E-15 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Tharo_2287 009aa95293241847fddb2ccec4e02454 242 Gene3D G3DSA:1.10.10.10 157 238 1.4E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2287 009aa95293241847fddb2ccec4e02454 242 SUPERFAMILY SSF46785 158 237 1.96E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_2287 009aa95293241847fddb2ccec4e02454 242 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 185 201 4.3E-11 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Tharo_2287 009aa95293241847fddb2ccec4e02454 242 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 201 216 4.3E-11 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Tharo_2287 009aa95293241847fddb2ccec4e02454 242 Pfam PF00027 Cyclic nucleotide-binding domain 41 124 5.2E-14 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Tharo_2287 009aa95293241847fddb2ccec4e02454 242 Gene3D G3DSA:2.60.120.10 35 155 6.1E-39 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Tharo_2287 009aa95293241847fddb2ccec4e02454 242 SMART SM00100 22 143 1.4E-8 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Tharo_2287 009aa95293241847fddb2ccec4e02454 242 Pfam PF13545 Crp-like helix-turn-helix domain 160 233 4.7E-19 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Tharo_2287 009aa95293241847fddb2ccec4e02454 242 SUPERFAMILY SSF51206 17 154 1.83E-26 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 Pfam PF01590 GAF domain 211 350 4.9E-8 T 14-10-2018 IPR003018 GAF domain GO:0005515 Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 SMART SM00086 441 483 4.5E-4 T 14-10-2018 IPR001610 PAC motif Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 SUPERFAMILY SSF55781 211 358 5.67E-17 T 14-10-2018 Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 SMART SM00065 42 187 0.032 T 14-10-2018 IPR003018 GAF domain GO:0005515 Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 SMART SM00065 210 364 2.2E-6 T 14-10-2018 IPR003018 GAF domain GO:0005515 Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 Gene3D G3DSA:3.20.20.450 657 912 1.1E-83 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 SUPERFAMILY SSF55781 45 188 6.11E-13 T 14-10-2018 Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 SMART SM00052 666 912 5.1E-89 T 14-10-2018 IPR001633 EAL domain Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 SMART SM00091 368 434 5.6E-10 T 14-10-2018 IPR000014 PAS domain Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 364 490 7.1E-21 T 14-10-2018 IPR000014 PAS domain Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 Pfam PF00990 Diguanylate cyclase, GGDEF domain 494 652 1.5E-45 T 14-10-2018 IPR000160 GGDEF domain Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 Gene3D G3DSA:3.30.450.40 40 169 1.6E-7 T 14-10-2018 IPR029016 GAF-like domain superfamily Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 SUPERFAMILY SSF55073 499 657 1.18E-48 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 Pfam PF00989 PAS fold 369 480 1.1E-13 T 14-10-2018 IPR013767 PAS fold GO:0006355 Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 SMART SM00267 483 656 4.6E-62 T 14-10-2018 IPR000160 GGDEF domain Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 SUPERFAMILY SSF55785 353 481 1.48E-25 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 Gene3D G3DSA:3.30.70.270 482 656 7.8E-56 T 14-10-2018 Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 Gene3D G3DSA:3.30.450.40 176 367 9.4E-21 T 14-10-2018 IPR029016 GAF-like domain superfamily Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 Gene3D G3DSA:3.30.450.20 368 481 1.8E-22 T 14-10-2018 Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 Pfam PF00563 EAL domain 673 907 5.1E-65 T 14-10-2018 IPR001633 EAL domain Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 SUPERFAMILY SSF141868 673 919 3.66E-75 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_1708 dca5c096173d3564b9ae53afc1efcd29 1053 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 490 656 4.5E-40 T 14-10-2018 IPR000160 GGDEF domain Tharo_2793 bf856d358aa829771a337b6eab9e7757 510 Gene3D G3DSA:3.90.226.10 257 510 2.0E-94 T 14-10-2018 Tharo_2793 bf856d358aa829771a337b6eab9e7757 510 Gene3D G3DSA:3.90.226.10 1 256 2.1E-98 T 14-10-2018 Tharo_2793 bf856d358aa829771a337b6eab9e7757 510 SUPERFAMILY SSF52096 251 510 1.09E-89 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_2793 bf856d358aa829771a337b6eab9e7757 510 Pfam PF01039 Carboxyl transferase domain 27 508 3.8E-198 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 Tharo_2793 bf856d358aa829771a337b6eab9e7757 510 SUPERFAMILY SSF52096 4 254 1.51E-80 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_2599 49e822e5477e4d9a81d8d374bf921efb 645 Pfam PF00005 ABC transporter 337 469 2.7E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_2599 49e822e5477e4d9a81d8d374bf921efb 645 SUPERFAMILY SSF52540 4 231 8.4E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2599 49e822e5477e4d9a81d8d374bf921efb 645 Gene3D G3DSA:3.40.50.300 11 279 7.8E-65 T 14-10-2018 Tharo_2599 49e822e5477e4d9a81d8d374bf921efb 645 Pfam PF12848 ABC transporter 224 297 6.6E-10 T 14-10-2018 IPR032781 ABC-transporter extension domain Tharo_2599 49e822e5477e4d9a81d8d374bf921efb 645 SMART SM00382 28 230 6.4E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2599 49e822e5477e4d9a81d8d374bf921efb 645 SMART SM00382 344 514 5.9E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2599 49e822e5477e4d9a81d8d374bf921efb 645 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_2599 49e822e5477e4d9a81d8d374bf921efb 645 SUPERFAMILY SSF52540 315 510 6.87E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2599 49e822e5477e4d9a81d8d374bf921efb 645 Gene3D G3DSA:3.40.50.300 282 548 4.4E-61 T 14-10-2018 Tharo_2599 49e822e5477e4d9a81d8d374bf921efb 645 Pfam PF00005 ABC transporter 19 185 6.1E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_2599 49e822e5477e4d9a81d8d374bf921efb 645 Pfam PF16326 ABC transporter C-terminal domain 572 640 5.1E-22 T 14-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 Tharo_2599 49e822e5477e4d9a81d8d374bf921efb 645 Gene3D G3DSA:1.10.287.380 563 644 8.7E-25 T 14-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 Tharo_1407 7779606e1be8f058a3a0cbc197007a5e 557 Hamap MF_00577 Urocanate hydratase [hutU]. 2 553 50.316 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 Tharo_1407 7779606e1be8f058a3a0cbc197007a5e 557 ProSitePatterns PS01233 Urocanase signature. 439 454 - T 14-10-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 Tharo_1407 7779606e1be8f058a3a0cbc197007a5e 557 Pfam PF01175 Urocanase Rossmann-like domain 138 346 1.4E-85 T 14-10-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 Tharo_1407 7779606e1be8f058a3a0cbc197007a5e 557 PIRSF PIRSF001423 2 556 2.9E-293 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 Tharo_1407 7779606e1be8f058a3a0cbc197007a5e 557 TIGRFAM TIGR01228 hutU: urocanate hydratase 8 551 3.3E-301 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 Tharo_1407 7779606e1be8f058a3a0cbc197007a5e 557 Pfam PF17391 Urocanase N-terminal domain 9 135 3.9E-62 T 14-10-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 Tharo_1407 7779606e1be8f058a3a0cbc197007a5e 557 Gene3D G3DSA:3.40.50.10730 139 346 6.1E-260 T 14-10-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 Tharo_1407 7779606e1be8f058a3a0cbc197007a5e 557 Pfam PF17392 Urocanase C-terminal domain 349 543 2.4E-91 T 14-10-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 Tharo_1407 7779606e1be8f058a3a0cbc197007a5e 557 Gene3D G3DSA:3.40.1770.10 14 539 6.1E-260 T 14-10-2018 Tharo_1407 7779606e1be8f058a3a0cbc197007a5e 557 SUPERFAMILY SSF111326 4 552 2.35E-261 T 14-10-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 Tharo_0858 354871f04436486a682c990f6e773605 916 SUPERFAMILY SSF53706 13 623 1.7E-114 T 14-10-2018 Tharo_0858 354871f04436486a682c990f6e773605 916 Pfam PF00384 Molybdopterin oxidoreductase 73 629 7.3E-29 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_0858 354871f04436486a682c990f6e773605 916 SUPERFAMILY SSF50692 781 913 2.94E-15 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Tharo_0858 354871f04436486a682c990f6e773605 916 Gene3D G3DSA:2.20.25.90 6 73 9.9E-6 T 14-10-2018 Tharo_0858 354871f04436486a682c990f6e773605 916 Gene3D G3DSA:3.40.50.740 492 657 2.7E-19 T 14-10-2018 Tharo_0858 354871f04436486a682c990f6e773605 916 Gene3D G3DSA:3.40.50.740 74 179 4.3E-12 T 14-10-2018 Tharo_0858 354871f04436486a682c990f6e773605 916 Pfam PF01568 Molydopterin dinucleotide binding domain 807 870 5.8E-10 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 Tharo_0858 354871f04436486a682c990f6e773605 916 Gene3D G3DSA:2.40.40.20 755 914 4.1E-15 T 14-10-2018 Tharo_0551 70a4c34b4074f0b3c697d7c831a21f1b 199 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 3 95 22.441 T 14-10-2018 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 Tharo_0551 70a4c34b4074f0b3c697d7c831a21f1b 199 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 5 95 5.0E-35 T 14-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 Tharo_0551 70a4c34b4074f0b3c697d7c831a21f1b 199 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 176 2.0E-43 T 14-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 Tharo_0551 70a4c34b4074f0b3c697d7c831a21f1b 199 Gene3D G3DSA:2.170.120.20 97 193 1.0E-25 T 14-10-2018 IPR037121 Ribosomal protein L25, C-terminal Tharo_0551 70a4c34b4074f0b3c697d7c831a21f1b 199 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 3 186 30.79 T 14-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 Tharo_0551 70a4c34b4074f0b3c697d7c831a21f1b 199 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 100 186 2.8E-27 T 14-10-2018 IPR020057 Ribosomal protein L25, beta domain Tharo_0551 70a4c34b4074f0b3c697d7c831a21f1b 199 Gene3D G3DSA:2.40.240.10 1 95 1.1E-30 T 14-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Tharo_0551 70a4c34b4074f0b3c697d7c831a21f1b 199 SUPERFAMILY SSF50715 1 192 7.32E-54 T 14-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Tharo_0551 70a4c34b4074f0b3c697d7c831a21f1b 199 Pfam PF01386 Ribosomal L25p family 6 92 1.4E-24 T 14-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 Tharo_3196 16d39379a2e75d8c450e6af86e10bd76 289 SMART SM01049 22 112 0.09 T 14-10-2018 IPR033480 Single Cache domain 2 Tharo_3196 16d39379a2e75d8c450e6af86e10bd76 289 SMART SM01049 161 240 1.2E-7 T 14-10-2018 IPR033480 Single Cache domain 2 Tharo_3196 16d39379a2e75d8c450e6af86e10bd76 289 Gene3D G3DSA:3.30.450.20 169 289 1.4E-18 T 14-10-2018 Tharo_3196 16d39379a2e75d8c450e6af86e10bd76 289 Gene3D G3DSA:3.30.450.20 30 168 1.6E-13 T 14-10-2018 Tharo_3196 16d39379a2e75d8c450e6af86e10bd76 289 Pfam PF08269 Cache domain 68 288 1.5E-23 T 14-10-2018 IPR004010 Double Cache domain 2 Tharo_1467 78fe0cd05e80ad16f2f5a4347e9d011d 86 Pfam PF13275 S4 domain 16 78 3.4E-23 T 14-10-2018 Tharo_1467 78fe0cd05e80ad16f2f5a4347e9d011d 86 SUPERFAMILY SSF55174 10 77 6.93E-19 T 14-10-2018 Tharo_1467 78fe0cd05e80ad16f2f5a4347e9d011d 86 Gene3D G3DSA:3.10.290.10 9 80 3.6E-23 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Tharo_3067 cce5f7fd986211553a8a6ee1ab68f47a 227 SMART SM00421 145 202 9.1E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_3067 cce5f7fd986211553a8a6ee1ab68f47a 227 SUPERFAMILY SSF52172 11 138 3.84E-29 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_3067 cce5f7fd986211553a8a6ee1ab68f47a 227 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_3067 cce5f7fd986211553a8a6ee1ab68f47a 227 SUPERFAMILY SSF46894 137 204 1.29E-17 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_3067 cce5f7fd986211553a8a6ee1ab68f47a 227 Pfam PF00072 Response regulator receiver domain 12 122 2.7E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_3067 cce5f7fd986211553a8a6ee1ab68f47a 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 201 1.3E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_3067 cce5f7fd986211553a8a6ee1ab68f47a 227 Gene3D G3DSA:1.10.10.10 146 204 1.1E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_3067 cce5f7fd986211553a8a6ee1ab68f47a 227 Gene3D G3DSA:3.40.50.2300 5 141 1.5E-43 T 14-10-2018 Tharo_3067 cce5f7fd986211553a8a6ee1ab68f47a 227 SMART SM00448 10 121 3.3E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_3067 cce5f7fd986211553a8a6ee1ab68f47a 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 1.5E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_3067 cce5f7fd986211553a8a6ee1ab68f47a 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 1.5E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_3067 cce5f7fd986211553a8a6ee1ab68f47a 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 1.5E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_1916 7352c30b81eefa873a174cd7f5733c32 201 SUPERFAMILY SSF143243 8 183 6.54E-55 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1916 7352c30b81eefa873a174cd7f5733c32 201 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 121 142 - T 14-10-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1916 7352c30b81eefa873a174cd7f5733c32 201 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 8 168 34.446 T 14-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1916 7352c30b81eefa873a174cd7f5733c32 201 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 87 148 4.0E-17 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1916 7352c30b81eefa873a174cd7f5733c32 201 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 31 159 1.3E-39 T 14-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1916 7352c30b81eefa873a174cd7f5733c32 201 Gene3D G3DSA:3.30.460.80 1 140 1.4E-42 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1916 7352c30b81eefa873a174cd7f5733c32 201 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 33 161 1.4E-41 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_2725 b3e0d66534922722fe60bccb6fb85f13 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 14-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2725 b3e0d66534922722fe60bccb6fb85f13 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 8.8E-35 T 14-10-2018 IPR027486 Ribosomal protein S10 domain Tharo_2725 b3e0d66534922722fe60bccb6fb85f13 103 SMART SM01403 7 101 3.4E-55 T 14-10-2018 IPR027486 Ribosomal protein S10 domain Tharo_2725 b3e0d66534922722fe60bccb6fb85f13 103 Gene3D G3DSA:3.30.70.600 1 102 5.4E-36 T 14-10-2018 IPR036838 Ribosomal protein S10 domain superfamily Tharo_2725 b3e0d66534922722fe60bccb6fb85f13 103 SUPERFAMILY SSF54999 5 102 1.27E-36 T 14-10-2018 IPR036838 Ribosomal protein S10 domain superfamily Tharo_2725 b3e0d66534922722fe60bccb6fb85f13 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.116 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2725 b3e0d66534922722fe60bccb6fb85f13 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.5E-44 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2725 b3e0d66534922722fe60bccb6fb85f13 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 9.3E-17 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2725 b3e0d66534922722fe60bccb6fb85f13 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 9.3E-17 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2725 b3e0d66534922722fe60bccb6fb85f13 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 9.3E-17 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 Gene3D G3DSA:3.30.70.270 414 585 1.9E-57 T 14-10-2018 Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 Pfam PF08447 PAS fold 59 146 9.5E-17 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 SUPERFAMILY SSF55785 296 402 1.92E-23 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 SMART SM00086 110 153 3.6E-5 T 14-10-2018 IPR001610 PAC motif Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 SMART SM00086 244 282 150.0 T 14-10-2018 IPR001610 PAC motif Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 SMART SM00086 362 404 0.27 T 14-10-2018 IPR001610 PAC motif Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 Pfam PF00990 Diguanylate cyclase, GGDEF domain 415 575 1.2E-45 T 14-10-2018 IPR000160 GGDEF domain Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 SMART SM00091 290 356 9.8E-8 T 14-10-2018 IPR000014 PAS domain Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 SMART SM00091 34 103 0.0042 T 14-10-2018 IPR000014 PAS domain Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 SMART SM00091 165 231 2.7E-4 T 14-10-2018 IPR000014 PAS domain Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 Gene3D G3DSA:3.30.450.20 30 100 9.0E-16 T 14-10-2018 Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 SUPERFAMILY SSF55785 43 156 1.06E-22 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 Gene3D G3DSA:3.30.450.20 158 290 3.3E-16 T 14-10-2018 Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 Pfam PF13426 PAS domain 301 402 7.7E-14 T 14-10-2018 IPR000014 PAS domain Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 SUPERFAMILY SSF55073 420 581 1.49E-49 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 Gene3D G3DSA:2.10.70.100 107 155 3.7E-8 T 14-10-2018 Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 Gene3D G3DSA:3.30.450.20 291 413 1.0E-30 T 14-10-2018 Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 SMART SM00267 404 580 4.2E-67 T 14-10-2018 IPR000160 GGDEF domain Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 Pfam PF13188 PAS domain 165 220 1.5E-9 T 14-10-2018 IPR000014 PAS domain Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 164 285 9.2E-9 T 14-10-2018 IPR000014 PAS domain Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 294 411 2.3E-18 T 14-10-2018 IPR000014 PAS domain Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 31 158 3.2E-11 T 14-10-2018 IPR000014 PAS domain Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 SUPERFAMILY SSF55785 150 280 3.49E-17 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_1473 7fb41e6c873a387d35367244a87e9eb8 587 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 411 579 1.4E-40 T 14-10-2018 IPR000160 GGDEF domain Tharo_0136 884ab2d87dc37aecdc7b80c16d717741 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 340 9.8E-158 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Tharo_0136 884ab2d87dc37aecdc7b80c16d717741 347 Pfam PF06723 MreB/Mbl protein 10 340 8.3E-150 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Tharo_0136 884ab2d87dc37aecdc7b80c16d717741 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 137 156 3.1E-63 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Tharo_0136 884ab2d87dc37aecdc7b80c16d717741 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 305 331 3.1E-63 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Tharo_0136 884ab2d87dc37aecdc7b80c16d717741 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 73 96 3.1E-63 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Tharo_0136 884ab2d87dc37aecdc7b80c16d717741 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 192 212 3.1E-63 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Tharo_0136 884ab2d87dc37aecdc7b80c16d717741 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 53 71 3.1E-63 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Tharo_0136 884ab2d87dc37aecdc7b80c16d717741 347 Gene3D G3DSA:3.30.420.40 159 322 3.5E-131 T 14-10-2018 Tharo_0136 884ab2d87dc37aecdc7b80c16d717741 347 SUPERFAMILY SSF53067 9 153 1.08E-38 T 14-10-2018 Tharo_0136 884ab2d87dc37aecdc7b80c16d717741 347 Gene3D G3DSA:3.30.420.40 13 332 3.5E-131 T 14-10-2018 Tharo_0136 884ab2d87dc37aecdc7b80c16d717741 347 Gene3D G3DSA:3.90.640.10 191 264 3.5E-131 T 14-10-2018 Tharo_0136 884ab2d87dc37aecdc7b80c16d717741 347 SUPERFAMILY SSF53067 154 337 4.44E-49 T 14-10-2018 Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 694 30.372 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 SMART SM00322 553 618 6.8E-11 T 14-10-2018 IPR004087 K Homology domain GO:0003676 Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 Pfam PF00013 KH domain 559 614 7.0E-11 T 14-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 11 692 0.0 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 SUPERFAMILY SSF54211 4 144 8.6E-52 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 Pfam PF00575 S1 RNA binding domain 620 691 4.9E-17 T 14-10-2018 IPR003029 S1 domain GO:0003676 Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 Pfam PF01138 3' exoribonuclease family, domain 1 325 457 1.2E-22 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 Pfam PF01138 3' exoribonuclease family, domain 1 16 144 7.5E-20 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 Gene3D G3DSA:2.40.50.140 623 693 3.7E-28 T 14-10-2018 Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 PIRSF PIRSF005499 2 698 4.8E-296 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 Gene3D G3DSA:3.30.230.70 3 229 7.7E-84 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 Gene3D G3DSA:3.30.230.70 233 550 5.8E-114 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 1.7E-12 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 Pfam PF03725 3' exoribonuclease family, domain 2 462 530 1.6E-5 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 SUPERFAMILY SSF50249 610 694 2.06E-21 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 SUPERFAMILY SSF55666 145 236 4.91E-30 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 SMART SM00316 621 691 3.0E-24 T 14-10-2018 IPR022967 RNA-binding domain, S1 Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 321 1.3E-20 T 14-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 Gene3D G3DSA:3.30.1370.10 551 622 1.9E-19 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 SUPERFAMILY SSF55666 454 561 6.73E-28 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 SUPERFAMILY SSF54791 556 623 6.73E-16 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 Tharo_1356 b6e7f158f61d787939e8951ec53e287d 698 SUPERFAMILY SSF54211 291 489 2.08E-48 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_2915 211190c1586e1e0ff684a306a64d5c9a 610 Gene3D G3DSA:3.30.1380.20 55 212 9.9E-7 T 14-10-2018 Tharo_2915 211190c1586e1e0ff684a306a64d5c9a 610 Pfam PF02954 Bacterial regulatory protein, Fis family 561 602 5.3E-12 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_2915 211190c1586e1e0ff684a306a64d5c9a 610 SUPERFAMILY SSF52540 264 498 1.15E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2915 211190c1586e1e0ff684a306a64d5c9a 610 SMART SM00989 147 209 3.5E-16 T 14-10-2018 IPR004096 4-vinyl reductase, 4VR Tharo_2915 211190c1586e1e0ff684a306a64d5c9a 610 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 568 585 5.3E-9 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_2915 211190c1586e1e0ff684a306a64d5c9a 610 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 585 605 5.3E-9 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_2915 211190c1586e1e0ff684a306a64d5c9a 610 SUPERFAMILY SSF111126 67 205 6.8E-8 T 14-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily Tharo_2915 211190c1586e1e0ff684a306a64d5c9a 610 Gene3D G3DSA:1.10.8.60 435 501 5.3E-22 T 14-10-2018 Tharo_2915 211190c1586e1e0ff684a306a64d5c9a 610 Gene3D G3DSA:1.10.10.60 547 605 4.6E-11 T 14-10-2018 Tharo_2915 211190c1586e1e0ff684a306a64d5c9a 610 ProDom PD485437 REGULATOR TRANSCRIPTIONAL FIS-TYPE HELIX-TURN-HELIX ACTIVATOR PLASMID FAMILY PHENOL-DEGRADATIVE FIS SIGMA-54 57 162 4.0E-54 T 14-10-2018 IPR010523 Activator of aromatic catabolism Tharo_2915 211190c1586e1e0ff684a306a64d5c9a 610 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 350 365 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Tharo_2915 211190c1586e1e0ff684a306a64d5c9a 610 SUPERFAMILY SSF46689 557 604 6.27E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_2915 211190c1586e1e0ff684a306a64d5c9a 610 Gene3D G3DSA:3.40.50.300 253 434 5.8E-64 T 14-10-2018 Tharo_2915 211190c1586e1e0ff684a306a64d5c9a 610 Pfam PF02830 V4R domain 148 208 6.1E-12 T 14-10-2018 IPR004096 4-vinyl reductase, 4VR Tharo_2915 211190c1586e1e0ff684a306a64d5c9a 610 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 288 301 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Tharo_2915 211190c1586e1e0ff684a306a64d5c9a 610 SMART SM00382 284 428 7.2E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2915 211190c1586e1e0ff684a306a64d5c9a 610 Pfam PF06505 Activator of aromatic catabolism 38 136 1.6E-33 T 14-10-2018 IPR010523 Activator of aromatic catabolism Tharo_2915 211190c1586e1e0ff684a306a64d5c9a 610 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 477 486 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Tharo_2915 211190c1586e1e0ff684a306a64d5c9a 610 Pfam PF00158 Sigma-54 interaction domain 264 430 3.4E-68 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Tharo_2479 41fcc183db179d9d930af9796f41705e 119 SUPERFAMILY SSF81273 79 117 2.08E-10 T 14-10-2018 Tharo_2479 41fcc183db179d9d930af9796f41705e 119 Pfam PF00816 H-NS histone family 10 113 1.7E-21 T 14-10-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 Tharo_2479 41fcc183db179d9d930af9796f41705e 119 Gene3D G3DSA:4.10.430.10 66 119 7.3E-12 T 14-10-2018 IPR037150 Histone-like protein H-NS, C-terminal domain superfamily GO:0003677 Tharo_2479 41fcc183db179d9d930af9796f41705e 119 SMART SM00528 74 119 1.2E-10 T 14-10-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 Tharo_0081 79d27d0bebae9c60073a000d74c374a6 389 Gene3D G3DSA:3.60.21.10 1 242 3.0E-29 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like Tharo_0081 79d27d0bebae9c60073a000d74c374a6 389 Pfam PF00149 Calcineurin-like phosphoesterase 3 96 2.3E-9 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Tharo_0081 79d27d0bebae9c60073a000d74c374a6 389 PIRSF PIRSF033093 1 372 4.3E-95 T 14-10-2018 IPR014577 Uncharacterised conserved protein UCP033093, metallophosphoesterase-type Tharo_0081 79d27d0bebae9c60073a000d74c374a6 389 SUPERFAMILY SSF56300 1 288 6.65E-34 T 14-10-2018 Tharo_0132 3149ee510e658eb34632db722faaecfb 1040 Gene3D G3DSA:3.40.50.300 279 496 8.2E-22 T 14-10-2018 Tharo_0132 3149ee510e658eb34632db722faaecfb 1040 SUPERFAMILY SSF52540 268 527 2.24E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0132 3149ee510e658eb34632db722faaecfb 1040 Pfam PF04851 Type III restriction enzyme, res subunit 279 486 1.4E-12 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 Tharo_0132 3149ee510e658eb34632db722faaecfb 1040 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 121 212 2.9E-11 T 14-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 Tharo_0132 3149ee510e658eb34632db722faaecfb 1040 Gene3D G3DSA:3.40.50.300 508 737 6.0E-19 T 14-10-2018 Tharo_0132 3149ee510e658eb34632db722faaecfb 1040 SMART SM00487 275 508 1.1E-7 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Tharo_3351 7f19683dd62b60ad8398c5b18d85bc86 219 Pfam PF00072 Response regulator receiver domain 3 112 6.3E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_3351 7f19683dd62b60ad8398c5b18d85bc86 219 SUPERFAMILY SSF52172 1 130 5.83E-40 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_3351 7f19683dd62b60ad8398c5b18d85bc86 219 SMART SM00448 1 112 7.2E-41 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_3351 7f19683dd62b60ad8398c5b18d85bc86 219 SMART SM00862 145 216 7.6E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_3351 7f19683dd62b60ad8398c5b18d85bc86 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 215 4.7E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_3351 7f19683dd62b60ad8398c5b18d85bc86 219 SUPERFAMILY SSF46894 118 215 2.44E-25 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_3351 7f19683dd62b60ad8398c5b18d85bc86 219 Gene3D G3DSA:1.10.10.10 122 218 5.9E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_3351 7f19683dd62b60ad8398c5b18d85bc86 219 Gene3D G3DSA:3.40.50.2300 1 121 7.6E-41 T 14-10-2018 Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 Gene3D G3DSA:3.40.190.10 118 225 5.6E-21 T 14-10-2018 Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 SUPERFAMILY SSF141868 779 1024 6.41E-87 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 37 282 3.5E-42 T 14-10-2018 Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 Pfam PF08447 PAS fold 378 464 5.2E-18 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 601 762 5.7E-45 T 14-10-2018 IPR000160 GGDEF domain Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 Gene3D G3DSA:2.10.70.100 426 474 1.7E-5 T 14-10-2018 Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 Gene3D G3DSA:3.30.450.20 480 602 1.2E-36 T 14-10-2018 Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 Gene3D G3DSA:3.30.450.20 351 423 3.8E-15 T 14-10-2018 Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 SUPERFAMILY SSF55073 610 764 1.41E-51 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 SUPERFAMILY SSF53850 45 281 2.88E-15 T 14-10-2018 Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 SMART SM00086 429 472 4.0E-6 T 14-10-2018 IPR001610 PAC motif Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 SMART SM00086 552 594 0.017 T 14-10-2018 IPR001610 PAC motif Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 Gene3D G3DSA:3.30.70.270 603 777 1.3E-61 T 14-10-2018 Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 SUPERFAMILY SSF55785 358 474 6.28E-19 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 SMART SM00052 772 1018 7.1E-105 T 14-10-2018 IPR001633 EAL domain Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 Pfam PF13426 PAS domain 491 592 8.8E-16 T 14-10-2018 IPR000014 PAS domain Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 SMART SM00091 480 546 7.1E-8 T 14-10-2018 IPR000014 PAS domain Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 SMART SM00091 353 422 0.12 T 14-10-2018 IPR000014 PAS domain Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 SUPERFAMILY SSF55785 491 591 1.92E-28 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 Gene3D G3DSA:3.40.190.10 41 238 5.6E-21 T 14-10-2018 Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 484 601 1.5E-20 T 14-10-2018 IPR000014 PAS domain Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 354 479 1.6E-8 T 14-10-2018 IPR000014 PAS domain Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 SMART SM00267 594 762 1.2E-70 T 14-10-2018 IPR000160 GGDEF domain Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 Pfam PF00563 EAL domain 778 1013 3.6E-78 T 14-10-2018 IPR001633 EAL domain Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 Gene3D G3DSA:3.20.20.450 778 1032 1.6E-95 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_1339 68e9c47a818100a2d18e155a180c435a 1042 Pfam PF00990 Diguanylate cyclase, GGDEF domain 605 757 1.1E-48 T 14-10-2018 IPR000160 GGDEF domain Tharo_2325 36cd22bf8a0613bf65fe7335bd6ace09 445 Gene3D G3DSA:3.30.565.10 299 439 1.5E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2325 36cd22bf8a0613bf65fe7335bd6ace09 445 Pfam PF00672 HAMP domain 180 229 7.7E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_2325 36cd22bf8a0613bf65fe7335bd6ace09 445 SUPERFAMILY SSF47384 217 287 8.83E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_2325 36cd22bf8a0613bf65fe7335bd6ace09 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 379 4.1E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2325 36cd22bf8a0613bf65fe7335bd6ace09 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 393 4.1E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2325 36cd22bf8a0613bf65fe7335bd6ace09 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 418 4.1E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2325 36cd22bf8a0613bf65fe7335bd6ace09 445 Gene3D G3DSA:1.10.287.130 184 292 2.7E-19 T 14-10-2018 Tharo_2325 36cd22bf8a0613bf65fe7335bd6ace09 445 SMART SM00387 331 440 7.6E-32 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2325 36cd22bf8a0613bf65fe7335bd6ace09 445 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 332 438 3.3E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2325 36cd22bf8a0613bf65fe7335bd6ace09 445 SUPERFAMILY SSF158472 180 230 4.84E-5 T 14-10-2018 Tharo_2325 36cd22bf8a0613bf65fe7335bd6ace09 445 SUPERFAMILY SSF55874 296 436 1.03E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2325 36cd22bf8a0613bf65fe7335bd6ace09 445 SMART SM00304 180 232 4.7E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_2325 36cd22bf8a0613bf65fe7335bd6ace09 445 SMART SM00388 233 291 9.5E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_0794 894e97cb24c8f7fcc79e92edfa1de8cb 840 SUPERFAMILY SSF47203 364 510 6.93E-24 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Tharo_0794 894e97cb24c8f7fcc79e92edfa1de8cb 840 SUPERFAMILY SSF56645 123 357 2.23E-45 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Tharo_0794 894e97cb24c8f7fcc79e92edfa1de8cb 840 Gene3D G3DSA:1.20.140.10 363 510 3.5E-94 T 14-10-2018 Tharo_0794 894e97cb24c8f7fcc79e92edfa1de8cb 840 Gene3D G3DSA:2.40.110.10 239 362 3.5E-94 T 14-10-2018 Tharo_0794 894e97cb24c8f7fcc79e92edfa1de8cb 840 Pfam PF09317 Domain of unknown function (DUF1974) 517 804 3.8E-110 T 14-10-2018 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 KEGG: 00071+1.3.8.8+1.3.8.7|KEGG: 00280+1.3.8.7|KEGG: 00410+1.3.8.7|KEGG: 00640+1.3.8.7|MetaCyc: PWY-7094|MetaCyc: PWY-7654 Tharo_0794 894e97cb24c8f7fcc79e92edfa1de8cb 840 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 126 235 2.7E-20 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Tharo_0794 894e97cb24c8f7fcc79e92edfa1de8cb 840 Gene3D G3DSA:1.10.540.10 126 238 3.5E-94 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Tharo_0794 894e97cb24c8f7fcc79e92edfa1de8cb 840 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 363 510 2.4E-13 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Tharo_0603 25c2fa6c08565eb98bb1ebafcbdca44c 253 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 136 246 2.0E-34 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 Tharo_0603 25c2fa6c08565eb98bb1ebafcbdca44c 253 Gene3D G3DSA:3.40.390.30 100 253 1.3E-48 T 14-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 Tharo_0603 25c2fa6c08565eb98bb1ebafcbdca44c 253 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 100 250 22.837 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 Tharo_0603 25c2fa6c08565eb98bb1ebafcbdca44c 253 SUPERFAMILY SSF55486 121 252 3.42E-43 T 14-10-2018 Tharo_0603 25c2fa6c08565eb98bb1ebafcbdca44c 253 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 216 226 - T 14-10-2018 IPR020549 Endoribonuclease YbeY, conserved site Tharo_0603 25c2fa6c08565eb98bb1ebafcbdca44c 253 Pfam PF02130 Uncharacterized protein family UPF0054 118 244 1.4E-34 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 Tharo_1395 7246de96afe58e485df1a98793555d3c 645 Pfam PF01266 FAD dependent oxidoreductase 255 612 7.3E-38 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Tharo_1395 7246de96afe58e485df1a98793555d3c 645 Gene3D G3DSA:3.30.9.10 340 558 1.6E-119 T 14-10-2018 Tharo_1395 7246de96afe58e485df1a98793555d3c 645 TIGRFAM TIGR03197 MnmC_Cterm: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain 255 638 1.1E-117 T 14-10-2018 IPR017610 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal GO:0008168|GO:0016645|GO:0055114 MetaCyc: PWY-7892 Tharo_1395 7246de96afe58e485df1a98793555d3c 645 Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. 7 637 25.735 T 14-10-2018 IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC GO:0004808|GO:0008033|GO:0008168|GO:0016645|GO:0055114 MetaCyc: PWY-7892 Tharo_1395 7246de96afe58e485df1a98793555d3c 645 Gene3D G3DSA:3.50.50.60 254 637 1.6E-119 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1395 7246de96afe58e485df1a98793555d3c 645 SUPERFAMILY SSF51905 256 536 4.86E-27 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1395 7246de96afe58e485df1a98793555d3c 645 Gene3D G3DSA:3.40.50.150 9 240 3.8E-96 T 14-10-2018 Tharo_1395 7246de96afe58e485df1a98793555d3c 645 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 111 233 9.2E-40 T 14-10-2018 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 MetaCyc: PWY-7892 Tharo_2061 5dbbea1affdd4a9ce1bd47f754647996 400 Pfam PF13288 DXP reductoisomerase C-terminal domain 271 387 7.9E-43 T 14-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Tharo_2061 5dbbea1affdd4a9ce1bd47f754647996 400 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 9 137 4.6E-45 T 14-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Tharo_2061 5dbbea1affdd4a9ce1bd47f754647996 400 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 151 239 3.3E-37 T 14-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Tharo_2061 5dbbea1affdd4a9ce1bd47f754647996 400 SUPERFAMILY SSF69055 302 395 2.88E-32 T 14-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Tharo_2061 5dbbea1affdd4a9ce1bd47f754647996 400 SUPERFAMILY SSF51735 6 155 1.41E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_2061 5dbbea1affdd4a9ce1bd47f754647996 400 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 9 392 46.977 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Tharo_2061 5dbbea1affdd4a9ce1bd47f754647996 400 PIRSF PIRSF006205 6 399 5.2E-153 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Tharo_2061 5dbbea1affdd4a9ce1bd47f754647996 400 Gene3D G3DSA:3.40.50.720 1 155 1.0E-52 T 14-10-2018 Tharo_2061 5dbbea1affdd4a9ce1bd47f754647996 400 SUPERFAMILY SSF55347 131 274 3.92E-59 T 14-10-2018 Tharo_2061 5dbbea1affdd4a9ce1bd47f754647996 400 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 8 393 6.0E-156 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Tharo_2061 5dbbea1affdd4a9ce1bd47f754647996 400 Gene3D G3DSA:1.10.1740.10 312 398 1.3E-28 T 14-10-2018 Tharo_1232 bcdd4594dda6b84237b05c359823e48d 217 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 140 155 - T 14-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 Tharo_1232 bcdd4594dda6b84237b05c359823e48d 217 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 15 216 4.4E-58 T 14-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 Tharo_1232 bcdd4594dda6b84237b05c359823e48d 217 Gene3D G3DSA:3.40.50.150 2 217 1.2E-69 T 14-10-2018 Tharo_1232 bcdd4594dda6b84237b05c359823e48d 217 SUPERFAMILY SSF53335 14 215 1.25E-39 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_1232 bcdd4594dda6b84237b05c359823e48d 217 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 10 216 33.757 T 14-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 Tharo_1232 bcdd4594dda6b84237b05c359823e48d 217 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 16 215 1.0E-54 T 14-10-2018 Tharo_1992 09662bbf96d7639d66ace75b45b458a8 580 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 76 497 3.0E-58 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 Tharo_1992 09662bbf96d7639d66ace75b45b458a8 580 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 191 216 - T 14-10-2018 IPR018212 Sodium/solute symporter, conserved site Tharo_1992 09662bbf96d7639d66ace75b45b458a8 580 Gene3D G3DSA:1.20.1730.10 63 548 8.0E-56 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily Tharo_1992 09662bbf96d7639d66ace75b45b458a8 580 Pfam PF00474 Sodium:solute symporter family 76 497 2.4E-112 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 Tharo_2160 fe2a4bb78dd534fec9a1a106be2cba9d 859 Gene3D G3DSA:1.10.1420.10 392 508 1.4E-93 T 14-10-2018 Tharo_2160 fe2a4bb78dd534fec9a1a106be2cba9d 859 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 1 854 0.0 T 14-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 Tharo_2160 fe2a4bb78dd534fec9a1a106be2cba9d 859 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 1 849 23.642 T 14-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 Tharo_2160 fe2a4bb78dd534fec9a1a106be2cba9d 859 SUPERFAMILY SSF52540 572 802 6.36E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2160 fe2a4bb78dd534fec9a1a106be2cba9d 859 Gene3D G3DSA:3.30.420.110 119 257 5.1E-26 T 14-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 Tharo_2160 fe2a4bb78dd534fec9a1a106be2cba9d 859 Pfam PF00488 MutS domain V 615 801 3.8E-82 T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Tharo_2160 fe2a4bb78dd534fec9a1a106be2cba9d 859 SUPERFAMILY SSF55271 2 106 1.57E-38 T 14-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 Tharo_2160 fe2a4bb78dd534fec9a1a106be2cba9d 859 Gene3D G3DSA:3.40.1170.10 1 112 5.8E-45 T 14-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 Tharo_2160 fe2a4bb78dd534fec9a1a106be2cba9d 859 Pfam PF05188 MutS domain II 129 247 1.4E-19 T 14-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 Tharo_2160 fe2a4bb78dd534fec9a1a106be2cba9d 859 Gene3D G3DSA:3.40.50.300 573 854 4.3E-96 T 14-10-2018 Tharo_2160 fe2a4bb78dd534fec9a1a106be2cba9d 859 Pfam PF05190 MutS family domain IV 433 524 2.0E-31 T 14-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 Tharo_2160 fe2a4bb78dd534fec9a1a106be2cba9d 859 Pfam PF01624 MutS domain I 2 110 2.3E-37 T 14-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 Tharo_2160 fe2a4bb78dd534fec9a1a106be2cba9d 859 SMART SM00533 278 596 1.0E-87 T 14-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 Tharo_2160 fe2a4bb78dd534fec9a1a106be2cba9d 859 SMART SM00534 611 798 6.7E-110 T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Tharo_2160 fe2a4bb78dd534fec9a1a106be2cba9d 859 SUPERFAMILY SSF53150 105 261 2.62E-33 T 14-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 Tharo_2160 fe2a4bb78dd534fec9a1a106be2cba9d 859 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 692 708 - T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Tharo_2160 fe2a4bb78dd534fec9a1a106be2cba9d 859 Pfam PF05192 MutS domain III 264 564 1.6E-32 T 14-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 Tharo_2160 fe2a4bb78dd534fec9a1a106be2cba9d 859 SUPERFAMILY SSF48334 262 570 4.19E-82 T 14-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily Tharo_2160 fe2a4bb78dd534fec9a1a106be2cba9d 859 PIRSF PIRSF037677 1 817 4.0E-133 T 14-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 Tharo_2160 fe2a4bb78dd534fec9a1a106be2cba9d 859 Gene3D G3DSA:1.10.1420.10 261 564 1.4E-93 T 14-10-2018 Tharo_0127 e077b9834ae7ce73820387575e4ba549 613 SUPERFAMILY SSF53335 6 612 3.95E-121 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_0127 e077b9834ae7ce73820387575e4ba549 613 Gene3D G3DSA:3.40.50.150 152 461 9.1E-92 T 14-10-2018 Tharo_0127 e077b9834ae7ce73820387575e4ba549 613 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 173 189 2.4E-11 T 14-10-2018 Tharo_0127 e077b9834ae7ce73820387575e4ba549 613 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 207 221 2.4E-11 T 14-10-2018 Tharo_0127 e077b9834ae7ce73820387575e4ba549 613 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 279 291 2.4E-11 T 14-10-2018 Tharo_0127 e077b9834ae7ce73820387575e4ba549 613 Pfam PF02384 N-6 DNA Methylase 152 451 1.9E-57 T 14-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 Tharo_0127 e077b9834ae7ce73820387575e4ba549 613 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 282 288 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Tharo_0127 e077b9834ae7ce73820387575e4ba549 613 Pfam PF12161 HsdM N-terminal domain 6 138 1.1E-20 T 14-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain Tharo_3152 46aa10d3efc4659be00968a4bf112242 217 SUPERFAMILY SSF53474 5 189 3.05E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_3152 46aa10d3efc4659be00968a4bf112242 217 Gene3D G3DSA:3.40.50.1820 7 209 2.2E-29 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_3152 46aa10d3efc4659be00968a4bf112242 217 Pfam PF12697 Alpha/beta hydrolase family 7 138 1.4E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_0346 73d2f0967fc9b6941d413da5ed3294a7 344 PIRSF PIRSF002888 3 327 6.1E-88 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 Tharo_0346 73d2f0967fc9b6941d413da5ed3294a7 344 SUPERFAMILY SSF101801 248 321 6.8E-11 T 14-10-2018 IPR036429 SpoA-like superfamily Tharo_0346 73d2f0967fc9b6941d413da5ed3294a7 344 Pfam PF02154 Flagellar motor switch protein FliM 37 230 7.6E-70 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 Tharo_0346 73d2f0967fc9b6941d413da5ed3294a7 344 Gene3D G3DSA:3.40.1550.10 43 232 1.2E-56 T 14-10-2018 IPR028976 CheC-like superfamily Tharo_0346 73d2f0967fc9b6941d413da5ed3294a7 344 PRINTS PR00955 Flagellar motor switch protein FliM signature 4 17 1.2E-25 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 Tharo_0346 73d2f0967fc9b6941d413da5ed3294a7 344 PRINTS PR00955 Flagellar motor switch protein FliM signature 212 230 1.2E-25 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 Tharo_0346 73d2f0967fc9b6941d413da5ed3294a7 344 PRINTS PR00955 Flagellar motor switch protein FliM signature 113 132 1.2E-25 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 Tharo_0346 73d2f0967fc9b6941d413da5ed3294a7 344 PRINTS PR00955 Flagellar motor switch protein FliM signature 88 104 1.2E-25 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 Tharo_0346 73d2f0967fc9b6941d413da5ed3294a7 344 SUPERFAMILY SSF103039 48 230 1.57E-19 T 14-10-2018 IPR028976 CheC-like superfamily Tharo_0346 73d2f0967fc9b6941d413da5ed3294a7 344 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 5 319 2.0E-99 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 Tharo_0346 73d2f0967fc9b6941d413da5ed3294a7 344 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 251 320 3.2E-15 T 14-10-2018 IPR001543 Surface presentation of antigen (SpoA) Tharo_0357 29f7b1a0320974a6e98899672c0496e3 664 SUPERFAMILY SSF58104 353 634 7.19E-64 T 14-10-2018 Tharo_0357 29f7b1a0320974a6e98899672c0496e3 664 SMART SM00283 386 633 3.0E-72 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_0357 29f7b1a0320974a6e98899672c0496e3 664 Gene3D G3DSA:1.10.287.950 334 635 1.1E-74 T 14-10-2018 Tharo_0357 29f7b1a0320974a6e98899672c0496e3 664 Pfam PF08376 Nitrate and nitrite sensing 59 296 1.7E-29 T 14-10-2018 IPR013587 Nitrate/nitrite sensing protein Tharo_0357 29f7b1a0320974a6e98899672c0496e3 664 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 449 600 2.6E-39 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_1887 2983328eabd7db1c49ee6c0bec9908da 556 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 548 2.5E-143 T 14-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 Tharo_1887 2983328eabd7db1c49ee6c0bec9908da 556 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 506 4.9E-14 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal Tharo_1887 2983328eabd7db1c49ee6c0bec9908da 556 SUPERFAMILY SSF52540 1 218 2.8E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1887 2983328eabd7db1c49ee6c0bec9908da 556 PIRSF PIRSF003128 1 553 4.7E-143 T 14-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 Tharo_1887 2983328eabd7db1c49ee6c0bec9908da 556 Gene3D G3DSA:3.40.50.300 1 201 1.5E-40 T 14-10-2018 Tharo_1887 2983328eabd7db1c49ee6c0bec9908da 556 SUPERFAMILY SSF52540 3 502 1.47E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1887 2983328eabd7db1c49ee6c0bec9908da 556 Gene3D G3DSA:3.40.50.300 250 549 1.6E-49 T 14-10-2018 Tharo_2197 325ebee6348cc95a8efab0c180a2b187 194 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 158 165 - T 14-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Tharo_2197 325ebee6348cc95a8efab0c180a2b187 194 SUPERFAMILY SSF46609 1 88 3.27E-34 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Tharo_2197 325ebee6348cc95a8efab0c180a2b187 194 Gene3D G3DSA:1.10.287.990 20 82 1.3E-24 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Tharo_2197 325ebee6348cc95a8efab0c180a2b187 194 Gene3D G3DSA:2.40.500.20 84 194 2.9E-38 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Tharo_2197 325ebee6348cc95a8efab0c180a2b187 194 SUPERFAMILY SSF54719 86 193 1.31E-40 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Tharo_2197 325ebee6348cc95a8efab0c180a2b187 194 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 1.5E-22 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Tharo_2197 325ebee6348cc95a8efab0c180a2b187 194 PRINTS PR01703 Manganese superoxide dismutase signature 66 79 1.5E-22 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Tharo_2197 325ebee6348cc95a8efab0c180a2b187 194 PRINTS PR01703 Manganese superoxide dismutase signature 156 168 1.5E-22 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Tharo_2197 325ebee6348cc95a8efab0c180a2b187 194 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 1.5E-22 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Tharo_2197 325ebee6348cc95a8efab0c180a2b187 194 PRINTS PR01703 Manganese superoxide dismutase signature 119 127 1.5E-22 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Tharo_2197 325ebee6348cc95a8efab0c180a2b187 194 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 90 191 3.0E-34 T 14-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Tharo_2197 325ebee6348cc95a8efab0c180a2b187 194 PIRSF PIRSF000349 1 194 1.1E-79 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Tharo_2197 325ebee6348cc95a8efab0c180a2b187 194 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 83 2.2E-33 T 14-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Tharo_2707 d7b10b35f6df42219ec5953bb767f8a7 174 Gene3D G3DSA:3.30.230.10 82 174 3.8E-36 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Tharo_2707 d7b10b35f6df42219ec5953bb767f8a7 174 Pfam PF00333 Ribosomal protein S5, N-terminal domain 19 82 1.7E-23 T 14-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 Tharo_2707 d7b10b35f6df42219ec5953bb767f8a7 174 SUPERFAMILY SSF54768 15 84 1.78E-20 T 14-10-2018 Tharo_2707 d7b10b35f6df42219ec5953bb767f8a7 174 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 171 33.08 T 14-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 Tharo_2707 d7b10b35f6df42219ec5953bb767f8a7 174 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 18 171 3.8E-60 T 14-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 Tharo_2707 d7b10b35f6df42219ec5953bb767f8a7 174 SUPERFAMILY SSF54211 87 167 4.55E-26 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_2707 d7b10b35f6df42219ec5953bb767f8a7 174 ProSitePatterns PS00585 Ribosomal protein S5 signature. 36 68 - T 14-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site Tharo_2707 d7b10b35f6df42219ec5953bb767f8a7 174 Gene3D G3DSA:3.30.160.20 10 80 8.1E-25 T 14-10-2018 Tharo_2707 d7b10b35f6df42219ec5953bb767f8a7 174 Pfam PF03719 Ribosomal protein S5, C-terminal domain 95 165 9.5E-30 T 14-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 Tharo_2770 87e63faaa0e78e362910725ae399b577 134 Pfam PF11026 Protein of unknown function (DUF2721) 4 118 7.9E-33 T 14-10-2018 IPR021279 Protein of unknown function DUF2721 Tharo_3377 a07fbc0d3dd0523dea8cb3d01a29ec8e 248 SMART SM00862 145 216 4.0E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_3377 a07fbc0d3dd0523dea8cb3d01a29ec8e 248 Gene3D G3DSA:1.10.10.10 124 227 1.3E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_3377 a07fbc0d3dd0523dea8cb3d01a29ec8e 248 Pfam PF00072 Response regulator receiver domain 3 112 1.9E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_3377 a07fbc0d3dd0523dea8cb3d01a29ec8e 248 SUPERFAMILY SSF46894 120 217 6.8E-27 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_3377 a07fbc0d3dd0523dea8cb3d01a29ec8e 248 SUPERFAMILY SSF52172 1 118 1.14E-35 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_3377 a07fbc0d3dd0523dea8cb3d01a29ec8e 248 SMART SM00448 1 112 4.0E-37 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_3377 a07fbc0d3dd0523dea8cb3d01a29ec8e 248 Gene3D G3DSA:3.40.50.2300 1 122 2.4E-38 T 14-10-2018 Tharo_3377 a07fbc0d3dd0523dea8cb3d01a29ec8e 248 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 215 2.4E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_0593 aab0ceff3c68761539379ecb4902fe41 505 Gene3D G3DSA:1.10.8.60 350 432 2.7E-16 T 14-10-2018 Tharo_0593 aab0ceff3c68761539379ecb4902fe41 505 Gene3D G3DSA:1.10.10.60 433 498 4.5E-8 T 14-10-2018 Tharo_0593 aab0ceff3c68761539379ecb4902fe41 505 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 396 405 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Tharo_0593 aab0ceff3c68761539379ecb4902fe41 505 SMART SM00382 199 342 4.0E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0593 aab0ceff3c68761539379ecb4902fe41 505 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 203 216 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Tharo_0593 aab0ceff3c68761539379ecb4902fe41 505 Pfam PF00158 Sigma-54 interaction domain 179 342 5.0E-68 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Tharo_0593 aab0ceff3c68761539379ecb4902fe41 505 Pfam PF02954 Bacterial regulatory protein, Fis family 455 489 2.3E-6 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_0593 aab0ceff3c68761539379ecb4902fe41 505 SUPERFAMILY SSF46689 445 495 4.3E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_0593 aab0ceff3c68761539379ecb4902fe41 505 SUPERFAMILY SSF52540 179 427 3.15E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0593 aab0ceff3c68761539379ecb4902fe41 505 Gene3D G3DSA:3.40.50.300 172 349 2.6E-62 T 14-10-2018 Tharo_0593 aab0ceff3c68761539379ecb4902fe41 505 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 265 280 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Tharo_2416 019637abdaa38dd7f35f73576c02158d 181 Gene3D G3DSA:2.60.40.2480 22 181 3.1E-71 T 14-10-2018 IPR038482 Periplasmic metal-binding protein tp34-type superfamily Tharo_2416 019637abdaa38dd7f35f73576c02158d 181 PIRSF PIRSF017018 3 181 1.3E-80 T 14-10-2018 IPR018470 Periplasmic metal-binding protein Tp34-type Tharo_2416 019637abdaa38dd7f35f73576c02158d 181 Pfam PF10634 Fe2+ transport protein 23 174 2.5E-68 T 14-10-2018 IPR018470 Periplasmic metal-binding protein Tp34-type Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 296 4.4E-48 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 699 715 - T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 Gene3D G3DSA:1.10.10.1100 441 494 1.6E-9 T 14-10-2018 Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 Gene3D G3DSA:3.30.413.10 651 817 5.1E-35 T 14-10-2018 Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 SUPERFAMILY SSF51905 2 197 5.89E-41 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 Pfam PF04324 BFD-like [2Fe-2S] binding domain 506 556 2.9E-14 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 Pfam PF04324 BFD-like [2Fe-2S] binding domain 442 490 5.0E-14 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 652 787 1.2E-23 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 151 176 3.2E-9 T 14-10-2018 Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 245 259 3.2E-9 T 14-10-2018 Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 3.2E-9 T 14-10-2018 Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 289 296 3.2E-9 T 14-10-2018 Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 6 813 9.5E-267 T 14-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 SUPERFAMILY SSF56014 653 819 7.33E-50 T 14-10-2018 Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 4.1E-13 T 14-10-2018 Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 296 4.1E-13 T 14-10-2018 Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 4.1E-13 T 14-10-2018 Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 244 260 4.1E-13 T 14-10-2018 Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 4.1E-13 T 14-10-2018 Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 PRINTS PR00397 Sirohaem Fe-binding site signature 699 717 1.8E-6 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 PRINTS PR00397 Sirohaem Fe-binding site signature 656 674 1.8E-6 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 582 644 6.1E-14 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 Gene3D G3DSA:3.30.390.30 333 411 4.5E-7 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 Gene3D G3DSA:3.50.50.60 114 256 4.8E-80 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 SUPERFAMILY SSF51905 152 321 1.3E-23 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 SUPERFAMILY SSF55124 542 661 6.21E-25 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 Gene3D G3DSA:3.50.50.60 7 296 4.8E-80 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1008 d975832cdab4b2fe53956428c7694e02 832 PIRSF PIRSF037149 1 831 0.0 T 14-10-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 Tharo_0614 27d1c3a4f64ec7a8f2d68f43909110ba 329 SMART SM00116 215 263 2.2 T 14-10-2018 IPR000644 CBS domain Tharo_0614 27d1c3a4f64ec7a8f2d68f43909110ba 329 SMART SM00116 280 328 0.0043 T 14-10-2018 IPR000644 CBS domain Tharo_0614 27d1c3a4f64ec7a8f2d68f43909110ba 329 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 50 318 1.6E-103 T 14-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 Tharo_0614 27d1c3a4f64ec7a8f2d68f43909110ba 329 Gene3D G3DSA:3.40.50.10490 9 200 8.5E-66 T 14-10-2018 Tharo_0614 27d1c3a4f64ec7a8f2d68f43909110ba 329 Gene3D G3DSA:3.10.580.10 201 326 4.8E-40 T 14-10-2018 Tharo_0614 27d1c3a4f64ec7a8f2d68f43909110ba 329 Pfam PF01380 SIS domain 46 177 1.3E-33 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Tharo_0614 27d1c3a4f64ec7a8f2d68f43909110ba 329 PIRSF PIRSF004692 2 329 2.3E-127 T 14-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 Tharo_0614 27d1c3a4f64ec7a8f2d68f43909110ba 329 SUPERFAMILY SSF53697 16 326 6.67E-67 T 14-10-2018 Tharo_0614 27d1c3a4f64ec7a8f2d68f43909110ba 329 Pfam PF00571 CBS domain 206 263 2.2E-5 T 14-10-2018 IPR000644 CBS domain Tharo_0614 27d1c3a4f64ec7a8f2d68f43909110ba 329 Pfam PF00571 CBS domain 273 326 4.6E-9 T 14-10-2018 IPR000644 CBS domain Tharo_3422 f050220963717b4a7400de59a5e9a454 209 Gene3D G3DSA:1.10.530.10 18 204 4.6E-5 T 14-10-2018 Tharo_3422 f050220963717b4a7400de59a5e9a454 209 SUPERFAMILY SSF53955 11 126 4.44E-22 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily Tharo_3422 f050220963717b4a7400de59a5e9a454 209 Pfam PF01464 Transglycosylase SLT domain 18 115 3.1E-5 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 Tharo_1853 7597d681433902ee8575644dc26ff5cb 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 1.3E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_1853 7597d681433902ee8575644dc26ff5cb 228 SUPERFAMILY SSF52172 1 180 4.1E-41 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1853 7597d681433902ee8575644dc26ff5cb 228 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 223 2.3E-92 T 14-10-2018 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 Tharo_1853 7597d681433902ee8575644dc26ff5cb 228 Pfam PF00072 Response regulator receiver domain 3 112 2.9E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1853 7597d681433902ee8575644dc26ff5cb 228 Gene3D G3DSA:3.40.50.2300 1 119 1.4E-41 T 14-10-2018 Tharo_1853 7597d681433902ee8575644dc26ff5cb 228 SMART SM00448 1 111 2.4E-44 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1853 7597d681433902ee8575644dc26ff5cb 228 Gene3D G3DSA:1.10.10.10 126 227 2.5E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1853 7597d681433902ee8575644dc26ff5cb 228 SMART SM00862 148 223 6.0E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_3101 8dbab0f27728790b8cfbbd88dc50346f 500 SUPERFAMILY SSF52540 191 495 1.02E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3101 8dbab0f27728790b8cfbbd88dc50346f 500 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 8 494 3.5E-182 T 14-10-2018 IPR004482 Mg chelatase-related protein Tharo_3101 8dbab0f27728790b8cfbbd88dc50346f 500 SMART SM00382 211 392 2.7E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_3101 8dbab0f27728790b8cfbbd88dc50346f 500 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 317 330 7.1E-5 T 14-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 Tharo_3101 8dbab0f27728790b8cfbbd88dc50346f 500 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 289 303 7.1E-5 T 14-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 Tharo_3101 8dbab0f27728790b8cfbbd88dc50346f 500 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 210 225 7.1E-5 T 14-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 Tharo_3101 8dbab0f27728790b8cfbbd88dc50346f 500 SUPERFAMILY SSF54211 11 168 6.45E-28 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_3101 8dbab0f27728790b8cfbbd88dc50346f 500 Gene3D G3DSA:3.30.230.10 39 168 5.1E-7 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Tharo_3101 8dbab0f27728790b8cfbbd88dc50346f 500 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 402 494 9.7E-31 T 14-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain Tharo_3101 8dbab0f27728790b8cfbbd88dc50346f 500 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 142 3.3E-44 T 14-10-2018 Tharo_3101 8dbab0f27728790b8cfbbd88dc50346f 500 Gene3D G3DSA:3.40.50.300 192 499 1.1E-52 T 14-10-2018 Tharo_3101 8dbab0f27728790b8cfbbd88dc50346f 500 Pfam PF01078 Magnesium chelatase, subunit ChlI 191 394 2.9E-96 T 14-10-2018 IPR000523 Magnesium chelatase ChlI domain Tharo_2799 c04924b2e0e617b27bd3cd50bc953b9e 447 Pfam PF02321 Outer membrane efflux protein 207 384 4.3E-24 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Tharo_2799 c04924b2e0e617b27bd3cd50bc953b9e 447 Pfam PF02321 Outer membrane efflux protein 2 183 2.4E-14 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Tharo_2799 c04924b2e0e617b27bd3cd50bc953b9e 447 SUPERFAMILY SSF56954 1 392 3.14E-70 T 14-10-2018 Tharo_2799 c04924b2e0e617b27bd3cd50bc953b9e 447 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 1 396 6.7E-80 T 14-10-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0015562|GO:0019867|GO:0055085 Tharo_2799 c04924b2e0e617b27bd3cd50bc953b9e 447 Gene3D G3DSA:1.20.1600.10 1 401 6.1E-75 T 14-10-2018 Tharo_1045 777ccd77d0c1bcff041c401662588c21 263 Pfam PF03746 LamB/YcsF family 10 248 2.0E-97 T 14-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 Tharo_1045 777ccd77d0c1bcff041c401662588c21 263 SUPERFAMILY SSF88713 9 258 8.89E-96 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Tharo_1045 777ccd77d0c1bcff041c401662588c21 263 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 8 252 43.535 T 14-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 Tharo_1045 777ccd77d0c1bcff041c401662588c21 263 Gene3D G3DSA:3.20.20.370 8 261 2.1E-99 T 14-10-2018 Tharo_2455 1778a450d8e1544dd8d3b2adc3c58921 1182 Pfam PF02811 PHP domain 25 191 2.0E-38 T 14-10-2018 IPR004013 PHP domain GO:0003824 Tharo_2455 1778a450d8e1544dd8d3b2adc3c58921 1182 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 311 751 7.6E-168 T 14-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_2455 1778a450d8e1544dd8d3b2adc3c58921 1182 SMART SM00481 24 91 1.2E-17 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal Tharo_2455 1778a450d8e1544dd8d3b2adc3c58921 1182 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 23 1052 0.0 T 14-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_2455 1778a450d8e1544dd8d3b2adc3c58921 1182 Gene3D G3DSA:3.20.20.140 7 288 1.1E-83 T 14-10-2018 Tharo_2455 1778a450d8e1544dd8d3b2adc3c58921 1182 SUPERFAMILY SSF89550 23 281 3.92E-12 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Tharo_2455 1778a450d8e1544dd8d3b2adc3c58921 1182 Gene3D G3DSA:1.10.10.1600 452 534 1.6E-22 T 14-10-2018 Tharo_2455 1778a450d8e1544dd8d3b2adc3c58921 1182 Pfam PF14579 Helix-hairpin-helix motif 825 925 2.2E-24 T 14-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_1148 800e5677789684dec3356bd477b28052 939 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 686 703 - T 14-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 Tharo_1148 800e5677789684dec3356bd477b28052 939 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 36 53 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1148 800e5677789684dec3356bd477b28052 939 Gene3D G3DSA:2.20.25.90 225 280 3.2E-17 T 14-10-2018 Tharo_1148 800e5677789684dec3356bd477b28052 939 SUPERFAMILY SSF53706 220 774 8.51E-185 T 14-10-2018 Tharo_1148 800e5677789684dec3356bd477b28052 939 Gene3D G3DSA:3.10.20.740 7 121 5.2E-24 T 14-10-2018 Tharo_1148 800e5677789684dec3356bd477b28052 939 Gene3D G3DSA:3.40.50.740 310 782 5.9E-167 T 14-10-2018 Tharo_1148 800e5677789684dec3356bd477b28052 939 SMART SM00926 224 281 3.1E-14 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1148 800e5677789684dec3356bd477b28052 939 Gene3D G3DSA:3.30.70.20 126 206 3.1E-21 T 14-10-2018 Tharo_1148 800e5677789684dec3356bd477b28052 939 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 226 278 1.1E-12 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1148 800e5677789684dec3356bd477b28052 939 Pfam PF01568 Molydopterin dinucleotide binding domain 827 932 3.4E-27 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 Tharo_1148 800e5677789684dec3356bd477b28052 939 Gene3D G3DSA:3.40.228.10 376 594 5.9E-167 T 14-10-2018 Tharo_1148 800e5677789684dec3356bd477b28052 939 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 189 200 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_1148 800e5677789684dec3356bd477b28052 939 Gene3D G3DSA:2.40.40.20 816 938 1.3E-41 T 14-10-2018 Tharo_1148 800e5677789684dec3356bd477b28052 939 Pfam PF00384 Molybdopterin oxidoreductase 284 740 1.7E-85 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1148 800e5677789684dec3356bd477b28052 939 SUPERFAMILY SSF54292 7 124 3.67E-32 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Tharo_1148 800e5677789684dec3356bd477b28052 939 SUPERFAMILY SSF54862 81 211 2.2E-26 T 14-10-2018 Tharo_1148 800e5677789684dec3356bd477b28052 939 SUPERFAMILY SSF50692 792 936 1.83E-42 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Tharo_1148 800e5677789684dec3356bd477b28052 939 Pfam PF13187 4Fe-4S dicluster domain 145 203 1.1E-7 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_1148 800e5677789684dec3356bd477b28052 939 PIRSF PIRSF036643 2 939 0.0 T 14-10-2018 Tharo_1148 800e5677789684dec3356bd477b28052 939 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 5 79 1.9E-17 T 14-10-2018 Tharo_2720 1a492f58d2f8d3a5dc23aabfe233ede4 91 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 4.2E-24 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2720 1a492f58d2f8d3a5dc23aabfe233ede4 91 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 4.2E-24 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2720 1a492f58d2f8d3a5dc23aabfe233ede4 91 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 4.2E-24 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2720 1a492f58d2f8d3a5dc23aabfe233ede4 91 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 90 4.6E-46 T 14-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 Tharo_2720 1a492f58d2f8d3a5dc23aabfe233ede4 91 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.932 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2720 1a492f58d2f8d3a5dc23aabfe233ede4 91 Pfam PF00203 Ribosomal protein S19 3 83 9.3E-37 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2720 1a492f58d2f8d3a5dc23aabfe233ede4 91 SUPERFAMILY SSF54570 3 84 8.11E-36 T 14-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2720 1a492f58d2f8d3a5dc23aabfe233ede4 91 PIRSF PIRSF002144 1 91 3.2E-33 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2720 1a492f58d2f8d3a5dc23aabfe233ede4 91 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 14-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2720 1a492f58d2f8d3a5dc23aabfe233ede4 91 Gene3D G3DSA:3.30.860.10 1 91 2.8E-41 T 14-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2618 460e18984ff78dfe338a142254310d4a 327 Pfam PF10117 McrBC 5-methylcytosine restriction system component 1 258 5.2E-74 T 14-10-2018 IPR019292 5-methylcytosine restriction system component Tharo_3133 abae3a5a42d558099f2526f13b9bad4b 281 Gene3D G3DSA:3.40.50.300 31 191 3.7E-10 T 14-10-2018 Tharo_3133 abae3a5a42d558099f2526f13b9bad4b 281 SMART SM00382 45 189 8.6E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_3133 abae3a5a42d558099f2526f13b9bad4b 281 SUPERFAMILY SSF52540 43 261 4.86E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3133 abae3a5a42d558099f2526f13b9bad4b 281 Pfam PF13401 AAA domain 45 174 1.1E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1586 abae3a5a42d558099f2526f13b9bad4b 281 Gene3D G3DSA:3.40.50.300 31 191 3.7E-10 T 14-10-2018 Tharo_1586 abae3a5a42d558099f2526f13b9bad4b 281 SMART SM00382 45 189 8.6E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1586 abae3a5a42d558099f2526f13b9bad4b 281 SUPERFAMILY SSF52540 43 261 4.86E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1586 abae3a5a42d558099f2526f13b9bad4b 281 Pfam PF13401 AAA domain 45 174 1.1E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1537 abae3a5a42d558099f2526f13b9bad4b 281 Gene3D G3DSA:3.40.50.300 31 191 3.7E-10 T 14-10-2018 Tharo_1537 abae3a5a42d558099f2526f13b9bad4b 281 SMART SM00382 45 189 8.6E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1537 abae3a5a42d558099f2526f13b9bad4b 281 SUPERFAMILY SSF52540 43 261 4.86E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1537 abae3a5a42d558099f2526f13b9bad4b 281 Pfam PF13401 AAA domain 45 174 1.1E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1212 4fea8f18d0135b9d6c0f45d1b3dd34a7 95 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 8.7E-17 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Tharo_1212 4fea8f18d0135b9d6c0f45d1b3dd34a7 95 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 8.7E-17 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Tharo_1212 4fea8f18d0135b9d6c0f45d1b3dd34a7 95 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 8.7E-17 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Tharo_1212 4fea8f18d0135b9d6c0f45d1b3dd34a7 95 Pfam PF00216 Bacterial DNA-binding protein 1 90 6.5E-29 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Tharo_1212 4fea8f18d0135b9d6c0f45d1b3dd34a7 95 Hamap MF_00381 Integration host factor subunit beta [ihfB]. 1 94 29.957 T 14-10-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 Tharo_1212 4fea8f18d0135b9d6c0f45d1b3dd34a7 95 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 93 4.5E-41 T 14-10-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 Tharo_1212 4fea8f18d0135b9d6c0f45d1b3dd34a7 95 Gene3D G3DSA:4.10.520.10 1 93 9.4E-32 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Tharo_1212 4fea8f18d0135b9d6c0f45d1b3dd34a7 95 SUPERFAMILY SSF47729 1 91 7.65E-30 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Tharo_1212 4fea8f18d0135b9d6c0f45d1b3dd34a7 95 SMART SM00411 1 91 2.3E-40 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Tharo_2842 d92eaf56de60ed2edcb85a6aa49a3387 1064 Pfam PF02687 FtsX-like permease family 971 1057 7.2E-11 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Tharo_2842 d92eaf56de60ed2edcb85a6aa49a3387 1064 Gene3D G3DSA:2.40.30.170 71 323 2.0E-75 T 14-10-2018 Tharo_2842 d92eaf56de60ed2edcb85a6aa49a3387 1064 Gene3D G3DSA:2.40.50.100 82 244 2.0E-75 T 14-10-2018 Tharo_2842 d92eaf56de60ed2edcb85a6aa49a3387 1064 SMART SM00382 456 650 2.8E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2842 d92eaf56de60ed2edcb85a6aa49a3387 1064 Gene3D G3DSA:3.40.50.300 426 653 9.1E-65 T 14-10-2018 Tharo_2842 d92eaf56de60ed2edcb85a6aa49a3387 1064 SUPERFAMILY SSF52540 427 649 3.08E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2842 d92eaf56de60ed2edcb85a6aa49a3387 1064 Gene3D G3DSA:1.10.287.470 116 207 2.0E-75 T 14-10-2018 Tharo_2842 d92eaf56de60ed2edcb85a6aa49a3387 1064 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 60 335 1.3E-43 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Tharo_2842 d92eaf56de60ed2edcb85a6aa49a3387 1064 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 68 316 1.6E-21 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Tharo_2842 d92eaf56de60ed2edcb85a6aa49a3387 1064 Pfam PF12704 MacB-like periplasmic core domain 691 909 7.0E-36 T 14-10-2018 IPR025857 MacB-like periplasmic core domain Tharo_2842 d92eaf56de60ed2edcb85a6aa49a3387 1064 ProSitePatterns PS00211 ABC transporters family signature. 568 582 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_2842 d92eaf56de60ed2edcb85a6aa49a3387 1064 Pfam PF00005 ABC transporter 447 595 5.4E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_2842 d92eaf56de60ed2edcb85a6aa49a3387 1064 SUPERFAMILY SSF111369 73 311 1.83E-24 T 14-10-2018 Tharo_2842 d92eaf56de60ed2edcb85a6aa49a3387 1064 Gene3D G3DSA:2.40.420.20 66 337 2.0E-75 T 14-10-2018 Tharo_1532 2950e794d36e96de108e6fa4dbecf61f 91 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 49 7.5E-13 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Tharo_1532 2950e794d36e96de108e6fa4dbecf61f 91 Gene3D G3DSA:3.40.1620.10 1 38 6.8E-9 T 14-10-2018 Tharo_1532 2950e794d36e96de108e6fa4dbecf61f 91 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 46 1.3E-11 T 14-10-2018 Tharo_1532 2950e794d36e96de108e6fa4dbecf61f 91 SUPERFAMILY SSF143120 1 51 2.09E-12 T 14-10-2018 IPR036165 YefM-like superfamily Tharo_0366 b204c62983a77909c873f27c0818418c 103 Gene3D G3DSA:1.10.260.40 44 103 7.0E-16 T 14-10-2018 Tharo_0366 b204c62983a77909c873f27c0818418c 103 SMART SM00530 43 96 3.6E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_0366 b204c62983a77909c873f27c0818418c 103 SUPERFAMILY SSF47413 44 90 1.47E-10 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_0366 b204c62983a77909c873f27c0818418c 103 Pfam PF13560 Helix-turn-helix domain 42 84 1.7E-9 T 14-10-2018 Tharo_0969 2d4a0feb1cde4dfda46b79ce489757f0 626 Pfam PF13721 SecD export protein N-terminal TM region 1 109 1.2E-32 T 14-10-2018 IPR027398 SecD export protein N-terminal TM domain Tharo_0969 2d4a0feb1cde4dfda46b79ce489757f0 626 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 356 590 1.2E-72 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Tharo_0969 2d4a0feb1cde4dfda46b79ce489757f0 626 Gene3D G3DSA:3.30.1360.200 287 428 7.0E-57 T 14-10-2018 Tharo_0969 2d4a0feb1cde4dfda46b79ce489757f0 626 Gene3D G3DSA:1.20.1640.10 455 602 1.7E-7 T 14-10-2018 Tharo_0969 2d4a0feb1cde4dfda46b79ce489757f0 626 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 129 597 8.2E-147 T 14-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 Tharo_0969 2d4a0feb1cde4dfda46b79ce489757f0 626 Gene3D G3DSA:3.30.70.3400 234 434 7.0E-57 T 14-10-2018 Tharo_0969 2d4a0feb1cde4dfda46b79ce489757f0 626 Pfam PF02355 Protein export membrane protein 429 600 1.4E-18 T 14-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial Tharo_0969 2d4a0feb1cde4dfda46b79ce489757f0 626 Pfam PF07549 SecD/SecF GG Motif 126 146 1.4E-5 T 14-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site Tharo_0969 2d4a0feb1cde4dfda46b79ce489757f0 626 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 612 47.29 T 14-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 Tharo_0969 2d4a0feb1cde4dfda46b79ce489757f0 626 SUPERFAMILY SSF82866 407 605 1.31E-38 T 14-10-2018 Tharo_1805 0bc84957e942168bccb39b77c5522d8c 528 Gene3D G3DSA:1.10.1130.10 26 291 6.0E-81 T 14-10-2018 Tharo_1805 0bc84957e942168bccb39b77c5522d8c 528 TIGRFAM TIGR04315 octaheme_Shew: octaheme c-type cytochrome, tetrathionate reductase family 25 479 7.9E-179 T 14-10-2018 IPR024673 Octaheme c-type cytochrome Tharo_1805 0bc84957e942168bccb39b77c5522d8c 528 Pfam PF11783 Cytochrome c bacterial 301 472 4.4E-62 T 14-10-2018 IPR024673 Octaheme c-type cytochrome Tharo_1805 0bc84957e942168bccb39b77c5522d8c 528 SUPERFAMILY SSF48695 31 476 6.85E-92 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily Tharo_1805 0bc84957e942168bccb39b77c5522d8c 528 Pfam PF13435 Cytochrome c554 and c-prime 46 125 0.012 T 14-10-2018 IPR023155 Cytochrome c-552/4 Tharo_1805 0bc84957e942168bccb39b77c5522d8c 528 PIRSF PIRSF039014 3 524 1.5E-162 T 14-10-2018 IPR024673 Octaheme c-type cytochrome Tharo_3264 26ff58b6e71107e8213d777ee466a963 581 Pfam PF02543 Carbamoyltransferase N-terminus 5 354 3.6E-54 T 14-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 Tharo_3264 26ff58b6e71107e8213d777ee466a963 581 Gene3D G3DSA:3.30.420.350 133 348 2.6E-81 T 14-10-2018 Tharo_3264 26ff58b6e71107e8213d777ee466a963 581 Gene3D G3DSA:3.30.420.40 14 354 2.6E-81 T 14-10-2018 Tharo_3264 26ff58b6e71107e8213d777ee466a963 581 SUPERFAMILY SSF53067 18 359 2.59E-12 T 14-10-2018 Tharo_3264 26ff58b6e71107e8213d777ee466a963 581 Gene3D G3DSA:3.90.870.20 368 578 7.9E-71 T 14-10-2018 IPR038152 Carbamoyltransferase, C-terminal domain superfamily Tharo_3264 26ff58b6e71107e8213d777ee466a963 581 Pfam PF16861 Carbamoyltransferase C-terminus 410 579 4.4E-62 T 14-10-2018 IPR031730 Carbamoyltransferase, C-terminal Tharo_1423 a55801cf024a705057e0ac752de22553 556 SUPERFAMILY SSF55124 1 126 3.11E-31 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Tharo_1423 a55801cf024a705057e0ac752de22553 556 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 119 273 2.7E-39 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Tharo_1423 a55801cf024a705057e0ac752de22553 556 Gene3D G3DSA:3.30.413.10 119 318 1.2E-77 T 14-10-2018 Tharo_1423 a55801cf024a705057e0ac752de22553 556 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 410 551 2.2E-11 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Tharo_1423 a55801cf024a705057e0ac752de22553 556 Gene3D G3DSA:3.30.413.10 408 555 1.4E-33 T 14-10-2018 Tharo_1423 a55801cf024a705057e0ac752de22553 556 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 53 109 8.0E-15 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Tharo_1423 a55801cf024a705057e0ac752de22553 556 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 345 398 1.5E-15 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Tharo_1423 a55801cf024a705057e0ac752de22553 556 Gene3D G3DSA:3.90.480.10 53 391 1.2E-77 T 14-10-2018 Tharo_1423 a55801cf024a705057e0ac752de22553 556 SUPERFAMILY SSF55124 252 421 1.21E-22 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Tharo_1423 a55801cf024a705057e0ac752de22553 556 SUPERFAMILY SSF56014 120 275 3.14E-43 T 14-10-2018 Tharo_1423 a55801cf024a705057e0ac752de22553 556 SUPERFAMILY SSF56014 408 549 9.03E-40 T 14-10-2018 Tharo_3050 8768b87220f8a1e21978aa66bafaf428 734 Gene3D G3DSA:3.30.450.20 6 126 4.5E-19 T 14-10-2018 Tharo_3050 8768b87220f8a1e21978aa66bafaf428 734 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 302 467 1.0E-36 T 14-10-2018 IPR000160 GGDEF domain Tharo_3050 8768b87220f8a1e21978aa66bafaf428 734 SUPERFAMILY SSF55073 311 470 3.69E-43 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_3050 8768b87220f8a1e21978aa66bafaf428 734 Pfam PF13185 GAF domain 151 294 2.9E-9 T 14-10-2018 IPR003018 GAF domain GO:0005515 Tharo_3050 8768b87220f8a1e21978aa66bafaf428 734 Gene3D G3DSA:3.30.450.40 149 303 3.5E-21 T 14-10-2018 IPR029016 GAF-like domain superfamily Tharo_3050 8768b87220f8a1e21978aa66bafaf428 734 Gene3D G3DSA:3.30.70.270 304 481 2.8E-53 T 14-10-2018 Tharo_3050 8768b87220f8a1e21978aa66bafaf428 734 SUPERFAMILY SSF55781 152 306 5.02E-20 T 14-10-2018 Tharo_3050 8768b87220f8a1e21978aa66bafaf428 734 SMART SM00086 86 128 1.6E-5 T 14-10-2018 IPR001610 PAC motif Tharo_3050 8768b87220f8a1e21978aa66bafaf428 734 Pfam PF08447 PAS fold 38 120 2.9E-11 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 Tharo_3050 8768b87220f8a1e21978aa66bafaf428 734 Pfam PF00563 EAL domain 486 720 1.2E-70 T 14-10-2018 IPR001633 EAL domain Tharo_3050 8768b87220f8a1e21978aa66bafaf428 734 SUPERFAMILY SSF55785 32 131 1.43E-14 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_3050 8768b87220f8a1e21978aa66bafaf428 734 SMART SM00267 295 469 5.4E-61 T 14-10-2018 IPR000160 GGDEF domain Tharo_3050 8768b87220f8a1e21978aa66bafaf428 734 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 132 9.8E-9 T 14-10-2018 IPR000014 PAS domain Tharo_3050 8768b87220f8a1e21978aa66bafaf428 734 SUPERFAMILY SSF141868 486 729 3.01E-89 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_3050 8768b87220f8a1e21978aa66bafaf428 734 Gene3D G3DSA:3.20.20.450 482 730 2.3E-103 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_3050 8768b87220f8a1e21978aa66bafaf428 734 SMART SM00065 150 303 2.1E-6 T 14-10-2018 IPR003018 GAF domain GO:0005515 Tharo_3050 8768b87220f8a1e21978aa66bafaf428 734 Pfam PF00990 Diguanylate cyclase, GGDEF domain 306 464 9.9E-43 T 14-10-2018 IPR000160 GGDEF domain Tharo_3050 8768b87220f8a1e21978aa66bafaf428 734 SMART SM00052 479 725 7.2E-120 T 14-10-2018 IPR001633 EAL domain Tharo_3050 8768b87220f8a1e21978aa66bafaf428 734 PIRSF PIRSF005925 38 734 8.9E-165 T 14-10-2018 IPR012226 Diguanylate cyclase/phosphodiesterase Tharo_2524 2db8ab0b217d3af233b37b42ff6143f3 915 SUPERFAMILY SSF141868 659 905 1.7E-90 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_2524 2db8ab0b217d3af233b37b42ff6143f3 915 SUPERFAMILY SSF52172 1 123 2.42E-32 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_2524 2db8ab0b217d3af233b37b42ff6143f3 915 Gene3D G3DSA:3.20.20.450 655 907 4.9E-103 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_2524 2db8ab0b217d3af233b37b42ff6143f3 915 Pfam PF00563 EAL domain 659 893 3.5E-72 T 14-10-2018 IPR001633 EAL domain Tharo_2524 2db8ab0b217d3af233b37b42ff6143f3 915 SMART SM00267 471 643 6.9E-62 T 14-10-2018 IPR000160 GGDEF domain Tharo_2524 2db8ab0b217d3af233b37b42ff6143f3 915 Gene3D G3DSA:3.30.450.20 341 488 3.4E-39 T 14-10-2018 Tharo_2524 2db8ab0b217d3af233b37b42ff6143f3 915 SMART SM00052 653 898 1.0E-113 T 14-10-2018 IPR001633 EAL domain Tharo_2524 2db8ab0b217d3af233b37b42ff6143f3 915 Pfam PF13185 GAF domain 194 338 1.5E-14 T 14-10-2018 IPR003018 GAF domain GO:0005515 Tharo_2524 2db8ab0b217d3af233b37b42ff6143f3 915 SMART SM00448 2 116 1.7E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2524 2db8ab0b217d3af233b37b42ff6143f3 915 Gene3D G3DSA:3.30.450.40 176 340 6.8E-23 T 14-10-2018 IPR029016 GAF-like domain superfamily Tharo_2524 2db8ab0b217d3af233b37b42ff6143f3 915 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 478 641 1.7E-42 T 14-10-2018 IPR000160 GGDEF domain Tharo_2524 2db8ab0b217d3af233b37b42ff6143f3 915 Pfam PF13426 PAS domain 365 470 1.3E-18 T 14-10-2018 IPR000014 PAS domain Tharo_2524 2db8ab0b217d3af233b37b42ff6143f3 915 Pfam PF00072 Response regulator receiver domain 4 116 3.9E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2524 2db8ab0b217d3af233b37b42ff6143f3 915 Pfam PF00990 Diguanylate cyclase, GGDEF domain 484 638 7.2E-48 T 14-10-2018 IPR000160 GGDEF domain Tharo_2524 2db8ab0b217d3af233b37b42ff6143f3 915 SUPERFAMILY SSF55781 195 350 4.8E-18 T 14-10-2018 Tharo_2524 2db8ab0b217d3af233b37b42ff6143f3 915 SMART SM00086 429 471 1.9E-10 T 14-10-2018 IPR001610 PAC motif Tharo_2524 2db8ab0b217d3af233b37b42ff6143f3 915 Gene3D G3DSA:3.40.50.2300 1 131 6.4E-32 T 14-10-2018 Tharo_2524 2db8ab0b217d3af233b37b42ff6143f3 915 SUPERFAMILY SSF55073 487 644 2.04E-49 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_2524 2db8ab0b217d3af233b37b42ff6143f3 915 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 360 478 3.1E-20 T 14-10-2018 IPR000014 PAS domain Tharo_2524 2db8ab0b217d3af233b37b42ff6143f3 915 Gene3D G3DSA:3.30.70.270 489 654 8.5E-59 T 14-10-2018 Tharo_2524 2db8ab0b217d3af233b37b42ff6143f3 915 SUPERFAMILY SSF55785 361 471 1.73E-26 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_1791 c2d69f356b148c04e21672392589e9bd 801 SMART SM00732 324 423 2.4E-38 T 14-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 Tharo_1791 c2d69f356b148c04e21672392589e9bd 801 SUPERFAMILY SSF47781 469 557 1.11E-28 T 14-10-2018 IPR010994 RuvA domain 2-like Tharo_1791 c2d69f356b148c04e21672392589e9bd 801 SUPERFAMILY SSF50249 636 723 2.01E-25 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_1791 c2d69f356b148c04e21672392589e9bd 801 SUPERFAMILY SSF53098 320 468 3.26E-50 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_1791 c2d69f356b148c04e21672392589e9bd 801 Gene3D G3DSA:2.40.50.140 630 721 1.6E-28 T 14-10-2018 Tharo_1791 c2d69f356b148c04e21672392589e9bd 801 Pfam PF16921 Tex protein YqgF-like domain 325 450 6.2E-51 T 14-10-2018 IPR032639 Tex protein, YqgF-like domain Tharo_1791 c2d69f356b148c04e21672392589e9bd 801 SUPERFAMILY SSF47781 559 631 3.11E-20 T 14-10-2018 IPR010994 RuvA domain 2-like Tharo_1791 c2d69f356b148c04e21672392589e9bd 801 Gene3D G3DSA:1.10.3500.10 112 497 6.0E-154 T 14-10-2018 IPR023323 Tex-like domain superfamily Tharo_1791 c2d69f356b148c04e21672392589e9bd 801 SUPERFAMILY SSF158832 3 319 5.75E-121 T 14-10-2018 Tharo_1791 c2d69f356b148c04e21672392589e9bd 801 Gene3D G3DSA:3.30.420.140 323 450 6.0E-154 T 14-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 Tharo_1791 c2d69f356b148c04e21672392589e9bd 801 Pfam PF09371 Tex-like protein N-terminal domain 9 192 9.4E-68 T 14-10-2018 IPR018974 Tex-like protein, N-terminal Tharo_1791 c2d69f356b148c04e21672392589e9bd 801 Pfam PF00575 S1 RNA binding domain 648 719 3.6E-21 T 14-10-2018 IPR003029 S1 domain GO:0003676 Tharo_1791 c2d69f356b148c04e21672392589e9bd 801 SMART SM00316 648 719 8.5E-25 T 14-10-2018 IPR022967 RNA-binding domain, S1 Tharo_1791 c2d69f356b148c04e21672392589e9bd 801 Gene3D G3DSA:1.10.150.310 498 629 1.1E-49 T 14-10-2018 Tharo_1791 c2d69f356b148c04e21672392589e9bd 801 Gene3D G3DSA:1.10.10.650 3 109 9.3E-41 T 14-10-2018 IPR023319 Tex-like protein, HTH domain superfamily Tharo_1791 c2d69f356b148c04e21672392589e9bd 801 Pfam PF12836 Helix-hairpin-helix motif 490 554 2.7E-28 T 14-10-2018 Tharo_1294 19a556f998ee6b9799e12f22394a9f2a 190 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 1 179 1.3E-63 T 14-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 Tharo_1294 19a556f998ee6b9799e12f22394a9f2a 190 Gene3D G3DSA:3.40.920.10 1 181 3.9E-55 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Tharo_1294 19a556f998ee6b9799e12f22394a9f2a 190 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 10 176 5.2E-33 T 14-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 Tharo_1294 19a556f998ee6b9799e12f22394a9f2a 190 SUPERFAMILY SSF53323 1 181 1.57E-47 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Tharo_0335 8bb65c9a53b17dbcd593f97c04cb0a09 260 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 182 260 5.4E-25 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain Tharo_0335 8bb65c9a53b17dbcd593f97c04cb0a09 260 Pfam PF00460 Flagella basal body rod protein 5 35 2.2E-12 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 Tharo_0335 8bb65c9a53b17dbcd593f97c04cb0a09 260 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 14-10-2018 IPR019776 Flagellar basal body rod protein, conserved site Tharo_0335 8bb65c9a53b17dbcd593f97c04cb0a09 260 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 4 259 2.9E-112 T 14-10-2018 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 Tharo_0335 8bb65c9a53b17dbcd593f97c04cb0a09 260 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 136 5.3E-47 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G Tharo_0335 8bb65c9a53b17dbcd593f97c04cb0a09 260 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 148 243 1.2E-29 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G Tharo_0335 8bb65c9a53b17dbcd593f97c04cb0a09 260 SUPERFAMILY SSF117143 93 222 7.45E-32 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like Tharo_1027 3ff8d17dca780b7a118f2a35413c4e96 108 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 5 97 23.16 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family Tharo_1027 3ff8d17dca780b7a118f2a35413c4e96 108 Gene3D G3DSA:3.30.1310.10 1 108 3.1E-42 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily Tharo_1027 3ff8d17dca780b7a118f2a35413c4e96 108 PIRSF PIRSF004555 3 108 5.7E-36 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family Tharo_1027 3ff8d17dca780b7a118f2a35413c4e96 108 SUPERFAMILY SSF82607 11 102 4.05E-34 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily Tharo_1027 3ff8d17dca780b7a118f2a35413c4e96 108 Pfam PF02575 YbaB/EbfC DNA-binding family 11 99 1.7E-32 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family Tharo_1027 3ff8d17dca780b7a118f2a35413c4e96 108 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 104 1.4E-32 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family Tharo_0059 08525dcaf7ef65d28170feed3c81335f 865 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 530 544 1.7E-26 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Tharo_0059 08525dcaf7ef65d28170feed3c81335f 865 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 322 331 1.7E-26 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Tharo_0059 08525dcaf7ef65d28170feed3c81335f 865 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 1.7E-26 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Tharo_0059 08525dcaf7ef65d28170feed3c81335f 865 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 191 209 1.7E-26 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Tharo_0059 08525dcaf7ef65d28170feed3c81335f 865 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 402 418 1.7E-26 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Tharo_0059 08525dcaf7ef65d28170feed3c81335f 865 Gene3D G3DSA:2.70.20.10 215 498 1.4E-160 T 14-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 Tharo_0059 08525dcaf7ef65d28170feed3c81335f 865 TIGRFAM TIGR01056 topB: DNA topoisomerase III 3 646 1.5E-164 T 14-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 Tharo_0059 08525dcaf7ef65d28170feed3c81335f 865 SUPERFAMILY SSF56712 3 620 1.16E-169 T 14-10-2018 IPR023405 DNA topoisomerase, type IA, core domain Tharo_0059 08525dcaf7ef65d28170feed3c81335f 865 Pfam PF01131 DNA topoisomerase 155 605 1.0E-113 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Tharo_0059 08525dcaf7ef65d28170feed3c81335f 865 Gene3D G3DSA:1.10.290.10 288 416 1.4E-160 T 14-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 Tharo_0059 08525dcaf7ef65d28170feed3c81335f 865 SMART SM00493 3 126 2.5E-11 T 14-10-2018 IPR006171 TOPRIM domain Tharo_0059 08525dcaf7ef65d28170feed3c81335f 865 SMART SM00437 279 567 2.1E-72 T 14-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 Tharo_0059 08525dcaf7ef65d28170feed3c81335f 865 SMART SM00436 126 221 5.5E-21 T 14-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 Tharo_0059 08525dcaf7ef65d28170feed3c81335f 865 Pfam PF13342 C-terminal repeat of topoisomerase 762 822 1.3E-18 T 14-10-2018 IPR025589 Topoisomerase C-terminal repeat Tharo_0059 08525dcaf7ef65d28170feed3c81335f 865 Pfam PF13342 C-terminal repeat of topoisomerase 657 715 7.9E-18 T 14-10-2018 IPR025589 Topoisomerase C-terminal repeat Tharo_0059 08525dcaf7ef65d28170feed3c81335f 865 Gene3D G3DSA:1.10.460.10 160 615 1.4E-160 T 14-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 Tharo_0059 08525dcaf7ef65d28170feed3c81335f 865 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 316 331 - T 14-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 Tharo_0059 08525dcaf7ef65d28170feed3c81335f 865 Gene3D G3DSA:3.40.50.140 3 153 9.0E-46 T 14-10-2018 Tharo_0059 08525dcaf7ef65d28170feed3c81335f 865 Pfam PF01751 Toprim domain 4 130 3.5E-10 T 14-10-2018 IPR006171 TOPRIM domain Tharo_3371 00a5adf6ea8933f652c04f41b6d0d557 655 SUPERFAMILY SSF51395 7 375 4.23E-83 T 14-10-2018 Tharo_3371 00a5adf6ea8933f652c04f41b6d0d557 655 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 515 539 1.8E-12 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_3371 00a5adf6ea8933f652c04f41b6d0d557 655 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 572 588 1.8E-12 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_3371 00a5adf6ea8933f652c04f41b6d0d557 655 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 391 413 1.8E-12 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_3371 00a5adf6ea8933f652c04f41b6d0d557 655 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 479 487 1.8E-12 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_3371 00a5adf6ea8933f652c04f41b6d0d557 655 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 11 344 7.9E-48 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 Tharo_3371 00a5adf6ea8933f652c04f41b6d0d557 655 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 390 619 1.5E-28 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Tharo_3371 00a5adf6ea8933f652c04f41b6d0d557 655 Gene3D G3DSA:3.40.50.720 391 650 8.0E-64 T 14-10-2018 Tharo_3371 00a5adf6ea8933f652c04f41b6d0d557 655 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 519 537 2.6E-16 T 14-10-2018 Tharo_3371 00a5adf6ea8933f652c04f41b6d0d557 655 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 603 619 2.6E-16 T 14-10-2018 Tharo_3371 00a5adf6ea8933f652c04f41b6d0d557 655 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 478 496 2.6E-16 T 14-10-2018 Tharo_3371 00a5adf6ea8933f652c04f41b6d0d557 655 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 392 411 2.6E-16 T 14-10-2018 Tharo_3371 00a5adf6ea8933f652c04f41b6d0d557 655 SUPERFAMILY SSF51905 367 655 4.4E-45 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_3371 00a5adf6ea8933f652c04f41b6d0d557 655 Gene3D G3DSA:3.20.20.70 8 381 1.2E-90 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_3371 00a5adf6ea8933f652c04f41b6d0d557 655 Gene3D G3DSA:3.50.50.60 490 611 8.0E-64 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_2686 b2bee2e7186f05b7abfd28f9754d5491 298 Gene3D G3DSA:1.10.10.10 4 91 6.8E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2686 b2bee2e7186f05b7abfd28f9754d5491 298 Pfam PF03466 LysR substrate binding domain 91 296 6.7E-44 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_2686 b2bee2e7186f05b7abfd28f9754d5491 298 Gene3D G3DSA:3.40.190.290 93 295 2.4E-62 T 14-10-2018 Tharo_2686 b2bee2e7186f05b7abfd28f9754d5491 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 3.6E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_2686 b2bee2e7186f05b7abfd28f9754d5491 298 SUPERFAMILY SSF46785 4 114 2.62E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_2686 b2bee2e7186f05b7abfd28f9754d5491 298 SUPERFAMILY SSF53850 91 297 2.02E-44 T 14-10-2018 Tharo_1201 70c97c2f543b6f545c9c93ed4751d507 163 SUPERFAMILY SSF54637 12 163 1.02E-45 T 14-10-2018 IPR029069 HotDog domain superfamily Tharo_1201 70c97c2f543b6f545c9c93ed4751d507 163 Gene3D G3DSA:3.10.129.10 7 145 1.6E-38 T 14-10-2018 Tharo_1201 70c97c2f543b6f545c9c93ed4751d507 163 Pfam PF13279 Thioesterase-like superfamily 18 136 1.5E-19 T 14-10-2018 Tharo_3005 1acf4818f1233dfd6fa7132abfeb65f3 323 Pfam PF12833 Helix-turn-helix domain 233 316 3.6E-23 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Tharo_3005 1acf4818f1233dfd6fa7132abfeb65f3 323 Gene3D G3DSA:1.10.10.60 211 318 4.9E-28 T 14-10-2018 Tharo_3005 1acf4818f1233dfd6fa7132abfeb65f3 323 SUPERFAMILY SSF46689 212 261 7.26E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_3005 1acf4818f1233dfd6fa7132abfeb65f3 323 SMART SM00342 227 314 3.6E-18 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Tharo_2501 f5e4614cd9d175ec17ca25e5cb302fe1 568 Gene3D G3DSA:1.20.1530.20 10 385 3.7E-72 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily Tharo_2501 f5e4614cd9d175ec17ca25e5cb302fe1 568 Pfam PF02254 TrkA-N domain 417 532 7.2E-17 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Tharo_2501 f5e4614cd9d175ec17ca25e5cb302fe1 568 Pfam PF00999 Sodium/hydrogen exchanger family 15 372 9.9E-50 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Tharo_2501 f5e4614cd9d175ec17ca25e5cb302fe1 568 Gene3D G3DSA:3.40.50.720 412 549 2.2E-28 T 14-10-2018 Tharo_2501 f5e4614cd9d175ec17ca25e5cb302fe1 568 SUPERFAMILY SSF51735 416 542 1.42E-21 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1971 2e489a05f7aae4a4336da1501224c01e 99 Pfam PF03795 YCII-related domain 1 95 7.4E-26 T 14-10-2018 IPR005545 YCII-related Tharo_1971 2e489a05f7aae4a4336da1501224c01e 99 Gene3D G3DSA:3.30.70.1060 1 98 1.2E-34 T 14-10-2018 Tharo_1971 2e489a05f7aae4a4336da1501224c01e 99 SUPERFAMILY SSF54909 1 97 3.93E-29 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel Tharo_2171 8a997bfa3d1cf228e36633ca82b0adc6 165 SUPERFAMILY SSF52833 1 154 3.31E-44 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_2171 8a997bfa3d1cf228e36633ca82b0adc6 165 Pfam PF00578 AhpC/TSA family 5 133 2.1E-32 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Tharo_2171 8a997bfa3d1cf228e36633ca82b0adc6 165 Gene3D G3DSA:3.40.30.10 3 155 4.4E-41 T 14-10-2018 Tharo_2171 8a997bfa3d1cf228e36633ca82b0adc6 165 PIRSF PIRSF000239 1 164 7.8E-24 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Tharo_2010 c439c7099a8f4752bd7e7b5d8b2d60b3 316 PIRSF PIRSF018005 4 316 1.9E-109 T 14-10-2018 IPR017804 Methyltransferase EgtD-like GO:0008168 Tharo_2010 c439c7099a8f4752bd7e7b5d8b2d60b3 316 SUPERFAMILY SSF53335 61 304 2.39E-11 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_2010 c439c7099a8f4752bd7e7b5d8b2d60b3 316 Gene3D G3DSA:3.40.50.150 44 213 1.9E-43 T 14-10-2018 Tharo_2010 c439c7099a8f4752bd7e7b5d8b2d60b3 316 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 18 314 6.2E-98 T 14-10-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent Tharo_2010 c439c7099a8f4752bd7e7b5d8b2d60b3 316 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 18 313 5.0E-110 T 14-10-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 Tharo_2924 ffba32eaee1ef140a55f5fdd6f4268d8 248 Gene3D G3DSA:3.40.50.720 2 248 1.0E-81 T 14-10-2018 Tharo_2924 ffba32eaee1ef140a55f5fdd6f4268d8 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 8.1E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2924 ffba32eaee1ef140a55f5fdd6f4268d8 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 8.1E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2924 ffba32eaee1ef140a55f5fdd6f4268d8 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 8.1E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2924 ffba32eaee1ef140a55f5fdd6f4268d8 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 245 4.4E-68 T 14-10-2018 Tharo_2924 ffba32eaee1ef140a55f5fdd6f4268d8 248 SUPERFAMILY SSF51735 4 247 1.48E-81 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_2924 ffba32eaee1ef140a55f5fdd6f4268d8 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.3E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2924 ffba32eaee1ef140a55f5fdd6f4268d8 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.3E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2924 ffba32eaee1ef140a55f5fdd6f4268d8 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.3E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2924 ffba32eaee1ef140a55f5fdd6f4268d8 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.3E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2924 ffba32eaee1ef140a55f5fdd6f4268d8 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.3E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2924 ffba32eaee1ef140a55f5fdd6f4268d8 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.3E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2924 ffba32eaee1ef140a55f5fdd6f4268d8 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Tharo_1640 c8d0f955ec7e5fca67ada0fed51bb5f1 276 Gene3D G3DSA:3.90.79.20 15 142 4.6E-13 T 14-10-2018 Tharo_1640 c8d0f955ec7e5fca67ada0fed51bb5f1 276 SUPERFAMILY SSF55811 97 250 4.33E-39 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Tharo_1640 c8d0f955ec7e5fca67ada0fed51bb5f1 276 Gene3D G3DSA:3.90.79.10 143 270 3.1E-35 T 14-10-2018 Tharo_1640 c8d0f955ec7e5fca67ada0fed51bb5f1 276 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 108 141 1.9E-7 T 14-10-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 Tharo_1640 c8d0f955ec7e5fca67ada0fed51bb5f1 276 ProSitePatterns PS00893 Nudix box signature. 176 197 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Tharo_1640 c8d0f955ec7e5fca67ada0fed51bb5f1 276 Pfam PF00293 NUDIX domain 145 250 3.5E-16 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Tharo_1640 c8d0f955ec7e5fca67ada0fed51bb5f1 276 PRINTS PR00502 NUDIX hydrolase family signature 171 185 8.5E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Tharo_1640 c8d0f955ec7e5fca67ada0fed51bb5f1 276 PRINTS PR00502 NUDIX hydrolase family signature 185 200 8.5E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Tharo_0223 ff837d0fa9409be2b2d43212f8e9ecb1 534 Pfam PF13005 zinc-finger binding domain of transposase IS66 143 186 1.9E-19 T 14-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 Tharo_0223 ff837d0fa9409be2b2d43212f8e9ecb1 534 Pfam PF03050 Transposase IS66 family 201 482 1.4E-93 T 14-10-2018 IPR004291 Transposase, IS66 Tharo_0223 ff837d0fa9409be2b2d43212f8e9ecb1 534 Pfam PF13007 Transposase C of IS166 homeodomain 60 135 5.2E-12 T 14-10-2018 IPR024463 Transposase TnpC, homeodomain Tharo_0223 ff837d0fa9409be2b2d43212f8e9ecb1 534 Pfam PF13817 IS66 C-terminal element 489 525 7.0E-14 T 14-10-2018 IPR039552 Transposase IS66, C-terminal Tharo_0321 ff837d0fa9409be2b2d43212f8e9ecb1 534 Pfam PF13005 zinc-finger binding domain of transposase IS66 143 186 1.9E-19 T 14-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 Tharo_0321 ff837d0fa9409be2b2d43212f8e9ecb1 534 Pfam PF03050 Transposase IS66 family 201 482 1.4E-93 T 14-10-2018 IPR004291 Transposase, IS66 Tharo_0321 ff837d0fa9409be2b2d43212f8e9ecb1 534 Pfam PF13007 Transposase C of IS166 homeodomain 60 135 5.2E-12 T 14-10-2018 IPR024463 Transposase TnpC, homeodomain Tharo_0321 ff837d0fa9409be2b2d43212f8e9ecb1 534 Pfam PF13817 IS66 C-terminal element 489 525 7.0E-14 T 14-10-2018 IPR039552 Transposase IS66, C-terminal Tharo_2673 ff837d0fa9409be2b2d43212f8e9ecb1 534 Pfam PF13005 zinc-finger binding domain of transposase IS66 143 186 1.9E-19 T 14-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 Tharo_2673 ff837d0fa9409be2b2d43212f8e9ecb1 534 Pfam PF03050 Transposase IS66 family 201 482 1.4E-93 T 14-10-2018 IPR004291 Transposase, IS66 Tharo_2673 ff837d0fa9409be2b2d43212f8e9ecb1 534 Pfam PF13007 Transposase C of IS166 homeodomain 60 135 5.2E-12 T 14-10-2018 IPR024463 Transposase TnpC, homeodomain Tharo_2673 ff837d0fa9409be2b2d43212f8e9ecb1 534 Pfam PF13817 IS66 C-terminal element 489 525 7.0E-14 T 14-10-2018 IPR039552 Transposase IS66, C-terminal Tharo_1132 81247896f4a819b5c2025a673acbd5e1 527 TIGRFAM TIGR02262 benz_CoA_lig: benzoate-CoA ligase family 20 526 4.4E-281 T 14-10-2018 IPR011957 Benzoate-CoA ligase family GO:0005524|GO:0016405 Tharo_1132 81247896f4a819b5c2025a673acbd5e1 527 Gene3D G3DSA:2.30.38.10 324 431 6.0E-35 T 14-10-2018 Tharo_1132 81247896f4a819b5c2025a673acbd5e1 527 Gene3D G3DSA:1.10.10.2900 253 323 1.8E-30 T 14-10-2018 Tharo_1132 81247896f4a819b5c2025a673acbd5e1 527 Gene3D G3DSA:3.40.50.980 17 252 1.8E-57 T 14-10-2018 Tharo_1132 81247896f4a819b5c2025a673acbd5e1 527 Pfam PF00501 AMP-binding enzyme 37 432 3.8E-85 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Tharo_1132 81247896f4a819b5c2025a673acbd5e1 527 Gene3D G3DSA:3.30.300.310 432 527 1.3E-27 T 14-10-2018 Tharo_1132 81247896f4a819b5c2025a673acbd5e1 527 Pfam PF13193 AMP-binding enzyme C-terminal domain 440 518 7.5E-20 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Tharo_1132 81247896f4a819b5c2025a673acbd5e1 527 SUPERFAMILY SSF56801 18 526 1.19E-142 T 14-10-2018 Tharo_1898 676014006c3fb974197417cb75b5fea9 276 SUPERFAMILY SSF51717 4 273 2.88E-97 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_1898 676014006c3fb974197417cb75b5fea9 276 Gene3D G3DSA:3.20.20.20 2 275 3.4E-101 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_1898 676014006c3fb974197417cb75b5fea9 276 Pfam PF00809 Pterin binding enzyme 19 257 7.9E-80 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_1898 676014006c3fb974197417cb75b5fea9 276 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 18 272 2.2E-92 T 14-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 Tharo_1898 676014006c3fb974197417cb75b5fea9 276 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 52 65 - T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_0965 56529fedbb794d1fa752df76be86d6a3 412 SUPERFAMILY SSF56266 16 409 6.93E-134 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Tharo_0965 56529fedbb794d1fa752df76be86d6a3 412 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 412 156.016 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Tharo_0965 56529fedbb794d1fa752df76be86d6a3 412 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 16 412 1.9E-121 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Tharo_0965 56529fedbb794d1fa752df76be86d6a3 412 Pfam PF01960 ArgJ family 22 412 3.5E-138 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Tharo_0965 56529fedbb794d1fa752df76be86d6a3 412 Gene3D G3DSA:3.60.70.12 11 278 2.4E-88 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Tharo_0965 56529fedbb794d1fa752df76be86d6a3 412 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 24 410 2.0E-172 T 14-10-2018 Tharo_0965 56529fedbb794d1fa752df76be86d6a3 412 Gene3D G3DSA:3.10.20.340 279 412 1.4E-41 T 14-10-2018 Tharo_1304 a79fe7ae0f603777e46199b70a856a2b 258 TIGRFAM TIGR03189 dienoyl_CoA_hyt: cyclohexa-1,5-dienecarbonyl-CoA hydratase 8 258 2.3E-156 T 14-10-2018 IPR017602 Cyclohexa-1,5-dienecarbonyl-CoA hydratase KEGG: 00362+4.2.1.100|MetaCyc: PWY-7401 Tharo_1304 a79fe7ae0f603777e46199b70a856a2b 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 257 1.7E-33 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Tharo_1304 a79fe7ae0f603777e46199b70a856a2b 258 Gene3D G3DSA:3.90.226.10 7 258 1.9E-52 T 14-10-2018 Tharo_1304 a79fe7ae0f603777e46199b70a856a2b 258 SUPERFAMILY SSF52096 10 258 2.05E-53 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_0750 8be17da3238bed578f5a66c0e8e99c64 615 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 18 470 2.2E-155 T 14-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 Tharo_0750 8be17da3238bed578f5a66c0e8e99c64 615 Gene3D G3DSA:3.40.50.300 217 348 1.0E-39 T 14-10-2018 Tharo_0750 8be17da3238bed578f5a66c0e8e99c64 615 Pfam PF09382 RQC domain 414 526 8.0E-40 T 14-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 Tharo_0750 8be17da3238bed578f5a66c0e8e99c64 615 Pfam PF16124 RecQ zinc-binding 351 412 1.5E-18 T 14-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain Tharo_0750 8be17da3238bed578f5a66c0e8e99c64 615 SMART SM00341 541 614 1.7E-9 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 Tharo_0750 8be17da3238bed578f5a66c0e8e99c64 615 SMART SM00487 25 225 2.5E-28 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Tharo_0750 8be17da3238bed578f5a66c0e8e99c64 615 SUPERFAMILY SSF52540 215 462 3.51E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0750 8be17da3238bed578f5a66c0e8e99c64 615 SMART SM00490 258 339 1.9E-25 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_0750 8be17da3238bed578f5a66c0e8e99c64 615 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 16 612 4.0E-241 T 14-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 Tharo_0750 8be17da3238bed578f5a66c0e8e99c64 615 Pfam PF00270 DEAD/DEAH box helicase 33 195 4.0E-17 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Tharo_0750 8be17da3238bed578f5a66c0e8e99c64 615 Pfam PF00570 HRDC domain 547 611 7.3E-23 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 Tharo_0750 8be17da3238bed578f5a66c0e8e99c64 615 SUPERFAMILY SSF52540 17 209 6.08E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0750 8be17da3238bed578f5a66c0e8e99c64 615 SUPERFAMILY SSF47819 543 613 3.27E-22 T 14-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 Tharo_0750 8be17da3238bed578f5a66c0e8e99c64 615 Gene3D G3DSA:1.10.10.10 350 530 3.4E-50 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0750 8be17da3238bed578f5a66c0e8e99c64 615 Gene3D G3DSA:1.10.150.80 544 614 1.1E-23 T 14-10-2018 Tharo_0750 8be17da3238bed578f5a66c0e8e99c64 615 SMART SM00956 419 522 1.3E-52 T 14-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 Tharo_0750 8be17da3238bed578f5a66c0e8e99c64 615 Gene3D G3DSA:3.40.50.300 9 216 4.0E-77 T 14-10-2018 Tharo_0750 8be17da3238bed578f5a66c0e8e99c64 615 Pfam PF00271 Helicase conserved C-terminal domain 233 338 5.7E-17 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_2870 af320d141ae52e14daba3a7f4a674ddf 184 Pfam PF08238 Sel1 repeat 103 138 6.7E-6 T 14-10-2018 IPR006597 Sel1-like repeat Tharo_2870 af320d141ae52e14daba3a7f4a674ddf 184 Pfam PF08238 Sel1 repeat 88 100 6.4 T 14-10-2018 IPR006597 Sel1-like repeat Tharo_2870 af320d141ae52e14daba3a7f4a674ddf 184 SUPERFAMILY SSF81901 66 140 2.62E-11 T 14-10-2018 Tharo_2870 af320d141ae52e14daba3a7f4a674ddf 184 SMART SM00671 71 102 110.0 T 14-10-2018 IPR006597 Sel1-like repeat Tharo_2870 af320d141ae52e14daba3a7f4a674ddf 184 SMART SM00671 103 138 6.8E-4 T 14-10-2018 IPR006597 Sel1-like repeat Tharo_2870 af320d141ae52e14daba3a7f4a674ddf 184 Gene3D G3DSA:1.25.40.10 58 153 2.7E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_2806 178ca0ce9b02318ce4ec4340b9b9345a 733 Gene3D G3DSA:3.90.70.10 28 155 2.3E-36 T 14-10-2018 Tharo_2806 178ca0ce9b02318ce4ec4340b9b9345a 733 SMART SM00382 524 710 8.1E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2806 178ca0ce9b02318ce4ec4340b9b9345a 733 SUPERFAMILY SSF90123 171 483 7.46E-48 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Tharo_2806 178ca0ce9b02318ce4ec4340b9b9345a 733 TIGRFAM TIGR03375 type_I_sec_LssB: type I secretion system ATPase 32 727 3.1E-296 T 14-10-2018 IPR017750 ATPase, type I secretion system Tharo_2806 178ca0ce9b02318ce4ec4340b9b9345a 733 ProSitePatterns PS00211 ABC transporters family signature. 636 650 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_2806 178ca0ce9b02318ce4ec4340b9b9345a 733 Pfam PF00664 ABC transporter transmembrane region 187 446 2.9E-17 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Tharo_2806 178ca0ce9b02318ce4ec4340b9b9345a 733 SUPERFAMILY SSF52540 491 720 1.78E-76 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2806 178ca0ce9b02318ce4ec4340b9b9345a 733 Gene3D G3DSA:1.20.1560.10 170 482 5.0E-48 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Tharo_2806 178ca0ce9b02318ce4ec4340b9b9345a 733 Pfam PF00005 ABC transporter 515 664 9.7E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_2806 178ca0ce9b02318ce4ec4340b9b9345a 733 Gene3D G3DSA:3.40.50.300 484 728 1.1E-83 T 14-10-2018 Tharo_1283 dc914dbbcad075e27052c977cce5d50f 107 ProDom PD591508 QUINOHEMOPROTEIN AMINE SUBUNIT DEHYDROGENASE GAMMA 1.4.99.- CATALYTIC QH-AMDH CTQ 3D-STRUCTURE 38 103 4.0E-23 T 14-10-2018 IPR015084 Quinohemoprotein amine dehydrogenase, gamma subunit, structural domain GO:0016638|GO:0055114 Tharo_1283 dc914dbbcad075e27052c977cce5d50f 107 SUPERFAMILY SSF69131 29 105 2.88E-38 T 14-10-2018 IPR036487 Quinohemoprotein amine dehydrogenase, gamma subunit structural domain superfamily Tharo_1283 dc914dbbcad075e27052c977cce5d50f 107 Pfam PF08992 Quinohemoprotein amine dehydrogenase, gamma subunit 31 104 4.8E-42 T 14-10-2018 IPR015084 Quinohemoprotein amine dehydrogenase, gamma subunit, structural domain GO:0016638|GO:0055114 Tharo_1283 dc914dbbcad075e27052c977cce5d50f 107 Gene3D G3DSA:4.10.940.10 29 107 3.2E-36 T 14-10-2018 IPR036487 Quinohemoprotein amine dehydrogenase, gamma subunit structural domain superfamily Tharo_1046 e01ca8046327b2f2e2d0440698dbe54f 634 Gene3D G3DSA:3.30.1360.40 4 84 3.5E-18 T 14-10-2018 Tharo_1046 e01ca8046327b2f2e2d0440698dbe54f 634 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 4 208 4.8E-70 T 14-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D Tharo_1046 e01ca8046327b2f2e2d0440698dbe54f 634 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 311 572 7.8E-70 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B Tharo_1046 e01ca8046327b2f2e2d0440698dbe54f 634 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 9 216 7.8E-50 T 14-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 Tharo_1046 e01ca8046327b2f2e2d0440698dbe54f 634 SMART SM00796 3 208 6.8E-85 T 14-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D Tharo_1046 e01ca8046327b2f2e2d0440698dbe54f 634 SUPERFAMILY SSF160467 4 99 6.41E-17 T 14-10-2018 Tharo_1046 e01ca8046327b2f2e2d0440698dbe54f 634 Gene3D G3DSA:2.40.100.10 464 600 1.0E-43 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily Tharo_1046 e01ca8046327b2f2e2d0440698dbe54f 634 SUPERFAMILY SSF50891 94 222 1.44E-42 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily Tharo_1046 e01ca8046327b2f2e2d0440698dbe54f 634 SUPERFAMILY SSF50891 466 579 1.48E-9 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily Tharo_1046 e01ca8046327b2f2e2d0440698dbe54f 634 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 289 591 7.4E-71 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B Tharo_1046 e01ca8046327b2f2e2d0440698dbe54f 634 Gene3D G3DSA:2.40.100.10 94 230 4.5E-53 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily Tharo_1046 e01ca8046327b2f2e2d0440698dbe54f 634 SMART SM00797 310 590 1.3E-79 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B Tharo_3177 1ddd6bb2cd715213f2a102c6f2a2c44d 344 SUPERFAMILY SSF90002 241 335 4.58E-20 T 14-10-2018 Tharo_3177 1ddd6bb2cd715213f2a102c6f2a2c44d 344 SMART SM00833 241 336 6.8E-24 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal Tharo_3177 1ddd6bb2cd715213f2a102c6f2a2c44d 344 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 242 335 1.9E-18 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal Tharo_3177 1ddd6bb2cd715213f2a102c6f2a2c44d 344 SUPERFAMILY SSF52540 11 193 5.89E-34 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3177 1ddd6bb2cd715213f2a102c6f2a2c44d 344 Gene3D G3DSA:3.30.1220.10 227 335 1.2E-19 T 14-10-2018 IPR036627 CobW-like, C-terminal domain superfamily Tharo_3177 1ddd6bb2cd715213f2a102c6f2a2c44d 344 Gene3D G3DSA:3.40.50.300 10 214 2.9E-60 T 14-10-2018 Tharo_3177 1ddd6bb2cd715213f2a102c6f2a2c44d 344 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 14 194 3.1E-45 T 14-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain Tharo_1755 76335bfaa6b2b84f2089e74c00c8bc27 256 Gene3D G3DSA:2.60.120.10 26 173 7.0E-40 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Tharo_1755 76335bfaa6b2b84f2089e74c00c8bc27 256 SUPERFAMILY SSF46785 178 253 9.79E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1755 76335bfaa6b2b84f2089e74c00c8bc27 256 Gene3D G3DSA:1.10.10.10 174 253 6.5E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1755 76335bfaa6b2b84f2089e74c00c8bc27 256 SUPERFAMILY SSF51206 35 172 9.95E-35 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like Tharo_1755 76335bfaa6b2b84f2089e74c00c8bc27 256 Pfam PF13545 Crp-like helix-turn-helix domain 179 253 2.9E-15 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Tharo_1755 76335bfaa6b2b84f2089e74c00c8bc27 256 SMART SM00100 41 159 1.6E-16 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Tharo_1755 76335bfaa6b2b84f2089e74c00c8bc27 256 SMART SM00419 199 247 1.2E-7 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Tharo_1755 76335bfaa6b2b84f2089e74c00c8bc27 256 Pfam PF00027 Cyclic nucleotide-binding domain 63 144 6.2E-19 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Tharo_2072 2c790e05424c68aad3146b94ca9326ae 302 SUPERFAMILY SSF53448 6 282 2.5E-64 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_2072 2c790e05424c68aad3146b94ca9326ae 302 Gene3D G3DSA:3.90.550.10 1 293 9.6E-90 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_2072 2c790e05424c68aad3146b94ca9326ae 302 Pfam PF00483 Nucleotidyl transferase 13 269 2.1E-29 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Tharo_2072 2c790e05424c68aad3146b94ca9326ae 302 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 6 269 3.6E-113 T 14-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 Tharo_2620 5108481d7f917bae4e660b53ee71c966 349 Gene3D G3DSA:3.40.50.11030 228 348 5.6E-17 T 14-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily Tharo_2620 5108481d7f917bae4e660b53ee71c966 349 Pfam PF01300 Telomere recombination 27 202 1.8E-58 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 Tharo_2620 5108481d7f917bae4e660b53ee71c966 349 PIRSF PIRSF004930 12 348 1.7E-107 T 14-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 Tharo_2620 5108481d7f917bae4e660b53ee71c966 349 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 19 212 4.2E-60 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 Tharo_2620 5108481d7f917bae4e660b53ee71c966 349 SUPERFAMILY SSF55821 16 214 5.19E-65 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily Tharo_2620 5108481d7f917bae4e660b53ee71c966 349 Gene3D G3DSA:3.90.870.10 12 216 6.0E-83 T 14-10-2018 Tharo_2620 5108481d7f917bae4e660b53ee71c966 349 Pfam PF03481 Putative GTP-binding controlling metal-binding 232 344 9.7E-18 T 14-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain Tharo_1915 798b14456e3e6cc5525b2e7a2a04ff50 158 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 42.12 T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1915 798b14456e3e6cc5525b2e7a2a04ff50 158 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1915 798b14456e3e6cc5525b2e7a2a04ff50 158 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 38 146 1.1E-21 T 14-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1915 798b14456e3e6cc5525b2e7a2a04ff50 158 SUPERFAMILY SSF56770 9 153 1.06E-66 T 14-10-2018 Tharo_1915 798b14456e3e6cc5525b2e7a2a04ff50 158 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 152 2.2E-77 T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1915 798b14456e3e6cc5525b2e7a2a04ff50 158 Gene3D G3DSA:3.40.50.12280 2 158 2.1E-78 T 14-10-2018 Tharo_1792 c347646a1b902be7578f1e541f3585b0 282 SUPERFAMILY SSF74650 4 279 1.19E-64 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Tharo_1792 c347646a1b902be7578f1e541f3585b0 282 Gene3D G3DSA:2.70.98.10 1 281 7.3E-85 T 14-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 Tharo_1792 c347646a1b902be7578f1e541f3585b0 282 Pfam PF01263 Aldose 1-epimerase 17 276 1.2E-41 T 14-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 Tharo_1792 c347646a1b902be7578f1e541f3585b0 282 PIRSF PIRSF016020 3 282 4.1E-67 T 14-10-2018 IPR025532 Glucose-6-phosphate 1-epimerase KEGG: 00010+5.1.3.15 Tharo_0606 0c22894bc64e16c8162b4c7316295b48 320 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 23 314 1.6E-160 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Tharo_0606 0c22894bc64e16c8162b4c7316295b48 320 Gene3D G3DSA:1.20.58.180 231 312 4.7E-36 T 14-10-2018 Tharo_0606 0c22894bc64e16c8162b4c7316295b48 320 SUPERFAMILY SSF55681 23 306 3.73E-133 T 14-10-2018 Tharo_0606 0c22894bc64e16c8162b4c7316295b48 320 Gene3D G3DSA:3.30.930.10 9 230 1.3E-109 T 14-10-2018 Tharo_0606 0c22894bc64e16c8162b4c7316295b48 320 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 22 307 60.937 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Tharo_0606 0c22894bc64e16c8162b4c7316295b48 320 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 154 174 8.9E-69 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Tharo_0606 0c22894bc64e16c8162b4c7316295b48 320 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 97 117 8.9E-69 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Tharo_0606 0c22894bc64e16c8162b4c7316295b48 320 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 267 283 8.9E-69 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Tharo_0606 0c22894bc64e16c8162b4c7316295b48 320 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 128 152 8.9E-69 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Tharo_0606 0c22894bc64e16c8162b4c7316295b48 320 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 177 192 8.9E-69 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Tharo_0606 0c22894bc64e16c8162b4c7316295b48 320 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 76 91 8.9E-69 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Tharo_0606 0c22894bc64e16c8162b4c7316295b48 320 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 24 306 1.3E-150 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Tharo_1475 37285f16e414c6bdea2ec83d431b080f 361 Pfam PF01609 Transposase DDE domain 210 352 3.7E-12 T 14-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 Tharo_1475 37285f16e414c6bdea2ec83d431b080f 361 Pfam PF05598 Transposase domain (DUF772) 53 125 1.5E-22 T 14-10-2018 IPR008490 Transposase InsH, N-terminal Tharo_0643 1f8e8e2111bae0392a136600a90ea2c0 115 SUPERFAMILY SSF54197 1 106 4.02E-41 T 14-10-2018 IPR036265 HIT-like superfamily Tharo_0643 1f8e8e2111bae0392a136600a90ea2c0 115 ProSitePatterns PS00892 HIT domain signature. 86 104 - T 14-10-2018 IPR019808 Histidine triad, conserved site Tharo_0643 1f8e8e2111bae0392a136600a90ea2c0 115 Gene3D G3DSA:3.30.428.10 1 107 1.8E-42 T 14-10-2018 IPR036265 HIT-like superfamily Tharo_0643 1f8e8e2111bae0392a136600a90ea2c0 115 Pfam PF01230 HIT domain 11 105 3.6E-27 T 14-10-2018 IPR001310 Histidine triad (HIT) protein Tharo_0643 1f8e8e2111bae0392a136600a90ea2c0 115 PRINTS PR00332 Histidine triad family signature 5 21 9.1E-22 T 14-10-2018 IPR001310 Histidine triad (HIT) protein Tharo_0643 1f8e8e2111bae0392a136600a90ea2c0 115 PRINTS PR00332 Histidine triad family signature 26 44 9.1E-22 T 14-10-2018 IPR001310 Histidine triad (HIT) protein Tharo_0643 1f8e8e2111bae0392a136600a90ea2c0 115 PRINTS PR00332 Histidine triad family signature 93 103 9.1E-22 T 14-10-2018 IPR001310 Histidine triad (HIT) protein Tharo_0467 9fc988e5a470271985dbe5e4f0ffd5c0 970 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 78 95 - T 14-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 Tharo_0467 9fc988e5a470271985dbe5e4f0ffd5c0 970 Gene3D G3DSA:3.40.50.740 139 629 2.9E-128 T 14-10-2018 Tharo_0467 9fc988e5a470271985dbe5e4f0ffd5c0 970 Gene3D G3DSA:3.40.228.10 207 406 2.9E-128 T 14-10-2018 Tharo_0467 9fc988e5a470271985dbe5e4f0ffd5c0 970 Gene3D G3DSA:2.20.25.90 74 126 6.0E-11 T 14-10-2018 Tharo_0467 9fc988e5a470271985dbe5e4f0ffd5c0 970 Pfam PF00384 Molybdopterin oxidoreductase 130 578 2.8E-54 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_0467 9fc988e5a470271985dbe5e4f0ffd5c0 970 SMART SM00926 73 127 4.7E-14 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_0467 9fc988e5a470271985dbe5e4f0ffd5c0 970 SUPERFAMILY SSF53706 73 661 1.44E-199 T 14-10-2018 Tharo_0467 9fc988e5a470271985dbe5e4f0ffd5c0 970 PIRSF PIRSF036643 795 969 1.3E-15 T 14-10-2018 Tharo_0467 9fc988e5a470271985dbe5e4f0ffd5c0 970 PIRSF PIRSF036643 35 597 3.2E-113 T 14-10-2018 Tharo_0467 9fc988e5a470271985dbe5e4f0ffd5c0 970 SUPERFAMILY SSF50692 806 970 3.16E-38 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Tharo_0467 9fc988e5a470271985dbe5e4f0ffd5c0 970 Pfam PF01568 Molydopterin dinucleotide binding domain 836 963 2.9E-19 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 Tharo_0467 9fc988e5a470271985dbe5e4f0ffd5c0 970 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 74 124 8.1E-11 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_0467 9fc988e5a470271985dbe5e4f0ffd5c0 970 Gene3D G3DSA:2.40.40.20 783 970 1.3E-45 T 14-10-2018 Tharo_1427 cdf9291efbf35b446361820e174ed5d2 375 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 11 364 2.4E-104 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 Tharo_1427 cdf9291efbf35b446361820e174ed5d2 375 Gene3D G3DSA:3.40.640.10 51 275 3.8E-108 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_1427 cdf9291efbf35b446361820e174ed5d2 375 SUPERFAMILY SSF53383 18 366 2.25E-80 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_1427 cdf9291efbf35b446361820e174ed5d2 375 Gene3D G3DSA:3.90.1150.10 27 360 3.8E-108 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_1427 cdf9291efbf35b446361820e174ed5d2 375 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 8 367 57.746 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 Tharo_1427 cdf9291efbf35b446361820e174ed5d2 375 Pfam PF00155 Aminotransferase class I and II 38 358 5.5E-50 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Tharo_3296 285d2348f18f5574186df0e9fc6774aa 504 Pfam PF00171 Aldehyde dehydrogenase family 25 491 4.0E-166 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Tharo_3296 285d2348f18f5574186df0e9fc6774aa 504 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 292 303 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 Tharo_3296 285d2348f18f5574186df0e9fc6774aa 504 SUPERFAMILY SSF53720 13 496 4.06E-163 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Tharo_3296 285d2348f18f5574186df0e9fc6774aa 504 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 259 266 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 Tharo_3296 285d2348f18f5574186df0e9fc6774aa 504 Gene3D G3DSA:3.40.309.10 263 461 5.0E-164 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Tharo_3296 285d2348f18f5574186df0e9fc6774aa 504 Gene3D G3DSA:3.40.605.10 33 489 5.0E-164 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Tharo_2442 3714a048e06372248006e775ff045e93 728 PIRSF PIRSF005925 290 727 4.5E-149 T 14-10-2018 IPR012226 Diguanylate cyclase/phosphodiesterase Tharo_2442 3714a048e06372248006e775ff045e93 728 PIRSF PIRSF005925 167 298 2.9E-10 T 14-10-2018 IPR012226 Diguanylate cyclase/phosphodiesterase Tharo_2442 3714a048e06372248006e775ff045e93 728 SMART SM00052 471 717 6.8E-133 T 14-10-2018 IPR001633 EAL domain Tharo_2442 3714a048e06372248006e775ff045e93 728 Gene3D G3DSA:3.30.70.270 301 474 8.0E-65 T 14-10-2018 Tharo_2442 3714a048e06372248006e775ff045e93 728 SUPERFAMILY SSF55785 184 291 8.38E-21 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_2442 3714a048e06372248006e775ff045e93 728 Gene3D G3DSA:3.30.450.20 171 300 1.8E-28 T 14-10-2018 Tharo_2442 3714a048e06372248006e775ff045e93 728 Pfam PF00563 EAL domain 477 711 1.2E-76 T 14-10-2018 IPR001633 EAL domain Tharo_2442 3714a048e06372248006e775ff045e93 728 SUPERFAMILY SSF46458 9 165 1.73E-29 T 14-10-2018 IPR009050 Globin-like superfamily Tharo_2442 3714a048e06372248006e775ff045e93 728 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 181 298 1.0E-13 T 14-10-2018 IPR000014 PAS domain Tharo_2442 3714a048e06372248006e775ff045e93 728 SMART SM00267 291 461 4.8E-70 T 14-10-2018 IPR000160 GGDEF domain Tharo_2442 3714a048e06372248006e775ff045e93 728 Pfam PF11563 Protoglobin 17 173 9.6E-32 T 14-10-2018 Tharo_2442 3714a048e06372248006e775ff045e93 728 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 298 457 4.3E-42 T 14-10-2018 IPR000160 GGDEF domain Tharo_2442 3714a048e06372248006e775ff045e93 728 Pfam PF00990 Diguanylate cyclase, GGDEF domain 302 455 2.4E-50 T 14-10-2018 IPR000160 GGDEF domain Tharo_2442 3714a048e06372248006e775ff045e93 728 SUPERFAMILY SSF141868 476 720 2.62E-93 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_2442 3714a048e06372248006e775ff045e93 728 Gene3D G3DSA:3.20.20.450 475 723 2.7E-110 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_2442 3714a048e06372248006e775ff045e93 728 Gene3D G3DSA:1.10.490.10 10 166 1.6E-39 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 Tharo_2442 3714a048e06372248006e775ff045e93 728 SMART SM00086 249 291 1.4E-9 T 14-10-2018 IPR001610 PAC motif Tharo_2442 3714a048e06372248006e775ff045e93 728 SUPERFAMILY SSF55073 307 462 4.63E-50 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_2442 3714a048e06372248006e775ff045e93 728 Pfam PF13426 PAS domain 188 290 2.7E-14 T 14-10-2018 IPR000014 PAS domain Tharo_2629 e6f871e5e8621bd44cd8036f1ddb777a 556 SUPERFAMILY SSF47005 247 289 2.49E-12 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Tharo_2629 e6f871e5e8621bd44cd8036f1ddb777a 556 SUPERFAMILY SSF51230 125 218 2.75E-23 T 14-10-2018 IPR011053 Single hybrid motif Tharo_2629 e6f871e5e8621bd44cd8036f1ddb777a 556 Pfam PF02817 e3 binding domain 250 284 6.9E-15 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 Tharo_2629 e6f871e5e8621bd44cd8036f1ddb777a 556 Pfam PF00364 Biotin-requiring enzyme 6 77 4.6E-20 T 14-10-2018 IPR000089 Biotin/lipoyl attachment Tharo_2629 e6f871e5e8621bd44cd8036f1ddb777a 556 Pfam PF00364 Biotin-requiring enzyme 127 198 8.4E-20 T 14-10-2018 IPR000089 Biotin/lipoyl attachment Tharo_2629 e6f871e5e8621bd44cd8036f1ddb777a 556 Gene3D G3DSA:4.10.320.10 250 294 3.7E-18 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Tharo_2629 e6f871e5e8621bd44cd8036f1ddb777a 556 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 105 556 1.9E-180 T 14-10-2018 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 Tharo_2629 e6f871e5e8621bd44cd8036f1ddb777a 556 SUPERFAMILY SSF51230 3 97 7.61E-24 T 14-10-2018 IPR011053 Single hybrid motif Tharo_2629 e6f871e5e8621bd44cd8036f1ddb777a 556 Gene3D G3DSA:2.40.50.100 3 83 1.3E-21 T 14-10-2018 Tharo_2629 e6f871e5e8621bd44cd8036f1ddb777a 556 Gene3D G3DSA:2.40.50.100 124 204 1.6E-20 T 14-10-2018 Tharo_2629 e6f871e5e8621bd44cd8036f1ddb777a 556 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 329 556 2.5E-76 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 Tharo_2629 e6f871e5e8621bd44cd8036f1ddb777a 556 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 149 178 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 Tharo_2629 e6f871e5e8621bd44cd8036f1ddb777a 556 Gene3D G3DSA:3.30.559.10 314 556 2.2E-90 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 Tharo_2629 e6f871e5e8621bd44cd8036f1ddb777a 556 SUPERFAMILY SSF52777 318 556 2.67E-82 T 14-10-2018 Tharo_2629 e6f871e5e8621bd44cd8036f1ddb777a 556 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 Tharo_0653 d6960f11732b57b389b0847673ff45e1 212 Pfam PF00498 FHA domain 16 79 2.2E-19 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Tharo_0653 d6960f11732b57b389b0847673ff45e1 212 SUPERFAMILY SSF49879 3 86 2.68E-26 T 14-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 Tharo_0653 d6960f11732b57b389b0847673ff45e1 212 SUPERFAMILY SSF49879 129 209 7.46E-8 T 14-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 Tharo_0653 d6960f11732b57b389b0847673ff45e1 212 SMART SM00240 15 65 4.1E-14 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Tharo_0653 d6960f11732b57b389b0847673ff45e1 212 Gene3D G3DSA:2.60.200.20 4 90 3.4E-26 T 14-10-2018 Tharo_3075 81ba32f1700c5dd3b9a169ee46af2827 424 SUPERFAMILY SSF103473 27 408 2.09E-52 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_3075 81ba32f1700c5dd3b9a169ee46af2827 424 Gene3D G3DSA:1.20.1720.10 33 411 1.8E-88 T 14-10-2018 Tharo_3075 81ba32f1700c5dd3b9a169ee46af2827 424 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 32 406 9.8E-81 T 14-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 Tharo_3075 81ba32f1700c5dd3b9a169ee46af2827 424 ProSitePatterns PS00216 Sugar transport proteins signature 1. 87 103 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Tharo_3075 81ba32f1700c5dd3b9a169ee46af2827 424 Pfam PF07690 Major Facilitator Superfamily 43 380 2.8E-34 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_2316 8eb63a2a1a41a4e0ddf7881fcd725fc5 66 Pfam PF00830 Ribosomal L28 family 1 50 1.1E-22 T 14-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2316 8eb63a2a1a41a4e0ddf7881fcd725fc5 66 Gene3D G3DSA:2.30.170.40 1 66 1.5E-27 T 14-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2316 8eb63a2a1a41a4e0ddf7881fcd725fc5 66 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 46 1.0E-19 T 14-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2316 8eb63a2a1a41a4e0ddf7881fcd725fc5 66 SUPERFAMILY SSF143800 1 65 4.32E-26 T 14-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_0763 617af32bad5039939b21cc79f47866d3 355 SUPERFAMILY SSF56935 21 355 5.8E-69 T 14-10-2018 Tharo_0763 617af32bad5039939b21cc79f47866d3 355 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 94 104 8.4E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 Tharo_0763 617af32bad5039939b21cc79f47866d3 355 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 347 355 8.4E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 Tharo_0763 617af32bad5039939b21cc79f47866d3 355 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 50 61 8.4E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 Tharo_0763 617af32bad5039939b21cc79f47866d3 355 Gene3D G3DSA:2.40.160.10 21 355 2.6E-78 T 14-10-2018 IPR023614 Porin domain superfamily Tharo_0763 617af32bad5039939b21cc79f47866d3 355 Pfam PF13609 Gram-negative porin 7 325 7.1E-57 T 14-10-2018 Tharo_0133 dff759bd6b9ef1b98befc31627a3d52b 490 Pfam PF02637 GatB domain 334 488 7.4E-49 T 14-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 Tharo_0133 dff759bd6b9ef1b98befc31627a3d52b 490 SMART SM00845 334 488 3.5E-77 T 14-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 Tharo_0133 dff759bd6b9ef1b98befc31627a3d52b 490 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 5 488 6.9E-161 T 14-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 Tharo_0133 dff759bd6b9ef1b98befc31627a3d52b 490 Pfam PF02934 GatB/GatE catalytic domain 8 293 8.3E-109 T 14-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 Tharo_0133 dff759bd6b9ef1b98befc31627a3d52b 490 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 5 489 37.006 T 14-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 Tharo_0133 dff759bd6b9ef1b98befc31627a3d52b 490 SUPERFAMILY SSF55931 7 302 1.18E-115 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Tharo_0133 dff759bd6b9ef1b98befc31627a3d52b 490 Gene3D G3DSA:1.10.10.410 428 489 9.2E-26 T 14-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal Tharo_0133 dff759bd6b9ef1b98befc31627a3d52b 490 SUPERFAMILY SSF89095 303 409 3.01E-31 T 14-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 Tharo_0133 dff759bd6b9ef1b98befc31627a3d52b 490 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 150 164 - T 14-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 Tharo_0133 dff759bd6b9ef1b98befc31627a3d52b 490 Gene3D G3DSA:1.10.150.380 303 421 1.3E-28 T 14-10-2018 Tharo_2977 3ca24f6941c598f548284cb530d46f32 214 Pfam PF13417 Glutathione S-transferase, N-terminal domain 9 78 4.2E-10 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 Tharo_2977 3ca24f6941c598f548284cb530d46f32 214 Gene3D G3DSA:3.40.30.10 3 196 2.6E-51 T 14-10-2018 Tharo_2977 3ca24f6941c598f548284cb530d46f32 214 SUPERFAMILY SSF47616 80 197 2.85E-13 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily Tharo_2977 3ca24f6941c598f548284cb530d46f32 214 SUPERFAMILY SSF52833 2 79 1.14E-16 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_2977 3ca24f6941c598f548284cb530d46f32 214 Gene3D G3DSA:1.20.1050.10 80 190 2.6E-51 T 14-10-2018 Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 SMART SM00388 153 218 7.7E-27 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 Pfam PF00512 His Kinase A (phospho-acceptor) domain 153 218 3.1E-21 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 SUPERFAMILY SSF52172 554 683 8.25E-43 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 Gene3D G3DSA:1.10.287.130 134 216 6.0E-30 T 14-10-2018 Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 PRINTS PR00344 Bacterial sensor protein C-terminal signature 341 359 2.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 PRINTS PR00344 Bacterial sensor protein C-terminal signature 306 320 2.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 334 2.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 378 2.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 Pfam PF00072 Response regulator receiver domain 399 514 5.1E-8 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 Pfam PF00072 Response regulator receiver domain 556 677 1.4E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 SMART SM00448 554 676 7.8E-44 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 SMART SM00448 396 514 5.3E-5 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 SUPERFAMILY SSF55874 207 379 1.83E-48 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 SUPERFAMILY SSF52172 396 519 1.12E-15 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 Gene3D G3DSA:3.40.50.12740 553 714 1.9E-50 T 14-10-2018 Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 SMART SM00387 265 381 1.6E-42 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 Gene3D G3DSA:3.30.565.10 217 382 1.1E-51 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 SUPERFAMILY SSF47226 659 805 1.14E-21 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 SUPERFAMILY SSF47384 139 219 3.92E-23 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 Gene3D G3DSA:3.40.50.2300 394 529 1.2E-13 T 14-10-2018 Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 Pfam PF01627 Hpt domain 728 792 7.3E-8 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 14 139 2.6E-11 T 14-10-2018 IPR000014 PAS domain Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 Gene3D G3DSA:1.20.120.160 715 809 4.9E-14 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 SUPERFAMILY SSF55785 23 134 5.93E-16 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 265 380 2.4E-33 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 Gene3D G3DSA:3.30.450.20 24 133 2.0E-20 T 14-10-2018 Tharo_1891 d4a7ac385a53327d0b234c2da1818bb2 836 Pfam PF08447 PAS fold 39 127 3.2E-13 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 Tharo_3027 98af94829336d7ee7e81a5d1f043062c 663 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 466 662 4.3E-20 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Tharo_3027 98af94829336d7ee7e81a5d1f043062c 663 Gene3D G3DSA:3.60.40.10 404 662 2.2E-50 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Tharo_3027 98af94829336d7ee7e81a5d1f043062c 663 Gene3D G3DSA:1.20.1480.50 308 396 5.9E-6 T 14-10-2018 Tharo_3027 98af94829336d7ee7e81a5d1f043062c 663 SMART SM00331 439 662 0.0016 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Tharo_3027 98af94829336d7ee7e81a5d1f043062c 663 SUPERFAMILY SSF158472 338 386 3.53E-5 T 14-10-2018 Tharo_3027 98af94829336d7ee7e81a5d1f043062c 663 Pfam PF00672 HAMP domain 338 385 1.6E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_3027 98af94829336d7ee7e81a5d1f043062c 663 SMART SM00304 338 389 1.0E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_1269 c38643a6ae3dfad4b0dad18f78e76b18 228 SMART SM00900 104 196 1.7E-33 T 14-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 Tharo_1269 c38643a6ae3dfad4b0dad18f78e76b18 228 Pfam PF04205 FMN-binding domain 104 193 1.3E-19 T 14-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 Tharo_1269 c38643a6ae3dfad4b0dad18f78e76b18 228 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 18 197 3.2E-54 T 14-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 Tharo_1269 c38643a6ae3dfad4b0dad18f78e76b18 228 Hamap MF_00479 Ion-translocating oxidoreductase complex subunit G [rsxG]. 9 198 24.231 T 14-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 Tharo_1269 c38643a6ae3dfad4b0dad18f78e76b18 228 PIRSF PIRSF006091 7 210 2.5E-64 T 14-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 Tharo_0810 17c9f803898ce16da743dd2a737f5803 76 Pfam PF15937 prlF antitoxin for toxin YhaV_toxin 6 47 2.3E-8 T 14-10-2018 IPR031848 PrlF antitoxin GO:0001558|GO:0003700|GO:0097351 Tharo_0810 17c9f803898ce16da743dd2a737f5803 76 SUPERFAMILY SSF89447 4 48 4.71E-8 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily Tharo_0810 17c9f803898ce16da743dd2a737f5803 76 ProDom PD030562 SUPPRESSOR HTRA PROTEASE TRANSCRIPTIONAL REGULATOR HTAR SOHA ABRB YDCA BLL1688 3 45 0.002 T 14-10-2018 Tharo_0810 17c9f803898ce16da743dd2a737f5803 76 SMART SM00966 5 51 6.7E-6 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Tharo_0810 17c9f803898ce16da743dd2a737f5803 76 Gene3D G3DSA:2.10.260.10 3 43 5.1E-9 T 14-10-2018 Tharo_0472 e72b8e03a05a41b65853930f000888dc 377 SUPERFAMILY SSF52540 8 344 3.15E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0472 e72b8e03a05a41b65853930f000888dc 377 Pfam PF00437 Type II/IV secretion system protein 126 253 1.2E-36 T 14-10-2018 IPR001482 Type II/IV secretion system protein Tharo_0472 e72b8e03a05a41b65853930f000888dc 377 Gene3D G3DSA:3.40.50.300 107 366 2.6E-88 T 14-10-2018 Tharo_0472 e72b8e03a05a41b65853930f000888dc 377 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 200 214 - T 14-10-2018 IPR001482 Type II/IV secretion system protein Tharo_0472 e72b8e03a05a41b65853930f000888dc 377 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 10 350 2.6E-137 T 14-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 Tharo_0472 e72b8e03a05a41b65853930f000888dc 377 Gene3D G3DSA:3.30.450.90 2 106 6.5E-29 T 14-10-2018 Tharo_1993 85c040e6b4faacbfb01d2fffcf1b5cce 479 Pfam PF08521 Two-component sensor kinase N-terminal 20 180 5.5E-32 T 14-10-2018 IPR013727 Two-component sensor kinase, N-terminal Tharo_1993 85c040e6b4faacbfb01d2fffcf1b5cce 479 SMART SM00388 258 320 1.1E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1993 85c040e6b4faacbfb01d2fffcf1b5cce 479 Pfam PF00512 His Kinase A (phospho-acceptor) domain 259 320 1.9E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1993 85c040e6b4faacbfb01d2fffcf1b5cce 479 SMART SM00304 205 257 0.0074 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_1993 85c040e6b4faacbfb01d2fffcf1b5cce 479 Gene3D G3DSA:1.10.287.130 209 319 5.1E-22 T 14-10-2018 Tharo_1993 85c040e6b4faacbfb01d2fffcf1b5cce 479 Pfam PF00672 HAMP domain 207 254 6.7E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_1993 85c040e6b4faacbfb01d2fffcf1b5cce 479 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 365 474 4.1E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1993 85c040e6b4faacbfb01d2fffcf1b5cce 479 Gene3D G3DSA:3.30.565.10 320 473 2.4E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1993 85c040e6b4faacbfb01d2fffcf1b5cce 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 472 2.6E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1993 85c040e6b4faacbfb01d2fffcf1b5cce 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 416 2.6E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1993 85c040e6b4faacbfb01d2fffcf1b5cce 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 430 2.6E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1993 85c040e6b4faacbfb01d2fffcf1b5cce 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 452 2.6E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1993 85c040e6b4faacbfb01d2fffcf1b5cce 479 SUPERFAMILY SSF55874 309 473 7.47E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1993 85c040e6b4faacbfb01d2fffcf1b5cce 479 SUPERFAMILY SSF47384 241 320 5.49E-15 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_1993 85c040e6b4faacbfb01d2fffcf1b5cce 479 SMART SM00387 365 475 5.0E-38 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_0867 5dad452bddbda3b335e7f3518633a150 267 SUPERFAMILY SSF46785 19 91 1.12E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0867 5dad452bddbda3b335e7f3518633a150 267 SUPERFAMILY SSF55781 76 261 5.36E-48 T 14-10-2018 Tharo_0867 5dad452bddbda3b335e7f3518633a150 267 Pfam PF09339 IclR helix-turn-helix domain 22 71 8.1E-14 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Tharo_0867 5dad452bddbda3b335e7f3518633a150 267 Gene3D G3DSA:1.10.10.10 17 89 1.1E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0867 5dad452bddbda3b335e7f3518633a150 267 Gene3D G3DSA:3.30.450.40 90 265 4.6E-55 T 14-10-2018 IPR029016 GAF-like domain superfamily Tharo_0867 5dad452bddbda3b335e7f3518633a150 267 Pfam PF01614 Bacterial transcriptional regulator 137 257 5.6E-28 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal Tharo_0867 5dad452bddbda3b335e7f3518633a150 267 SMART SM00346 19 108 1.8E-24 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Tharo_2702 6160011ae59c62cbc23272359b27da5a 120 Gene3D G3DSA:1.10.8.50 1 71 2.8E-29 T 14-10-2018 Tharo_2702 6160011ae59c62cbc23272359b27da5a 120 PIRSF PIRSF002134 1 120 6.4E-44 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2702 6160011ae59c62cbc23272359b27da5a 120 Pfam PF00416 Ribosomal protein S13/S18 3 108 1.6E-32 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2702 6160011ae59c62cbc23272359b27da5a 120 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 27.721 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2702 6160011ae59c62cbc23272359b27da5a 120 Gene3D G3DSA:4.10.910.10 72 117 8.4E-26 T 14-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2702 6160011ae59c62cbc23272359b27da5a 120 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 5.0E-54 T 14-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2702 6160011ae59c62cbc23272359b27da5a 120 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 14-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2702 6160011ae59c62cbc23272359b27da5a 120 SUPERFAMILY SSF46946 2 114 1.85E-46 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 Tharo_0350 b1ac6df89ab5662ed680b7a38aaf0883 152 PRINTS PR01004 Flagellar FliJ protein signature 5 27 1.2E-8 T 14-10-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 Tharo_0350 b1ac6df89ab5662ed680b7a38aaf0883 152 PRINTS PR01004 Flagellar FliJ protein signature 64 85 1.2E-8 T 14-10-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 Tharo_0350 b1ac6df89ab5662ed680b7a38aaf0883 152 PRINTS PR01004 Flagellar FliJ protein signature 28 44 1.2E-8 T 14-10-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 Tharo_0350 b1ac6df89ab5662ed680b7a38aaf0883 152 PRINTS PR01004 Flagellar FliJ protein signature 45 62 1.2E-8 T 14-10-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 Tharo_0350 b1ac6df89ab5662ed680b7a38aaf0883 152 PRINTS PR01004 Flagellar FliJ protein signature 109 127 1.2E-8 T 14-10-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 Tharo_0350 b1ac6df89ab5662ed680b7a38aaf0883 152 PRINTS PR01004 Flagellar FliJ protein signature 127 147 1.2E-8 T 14-10-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 Tharo_0350 b1ac6df89ab5662ed680b7a38aaf0883 152 PRINTS PR01004 Flagellar FliJ protein signature 87 108 1.2E-8 T 14-10-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 Tharo_0350 b1ac6df89ab5662ed680b7a38aaf0883 152 PIRSF PIRSF019404 1 150 8.8E-34 T 14-10-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 Tharo_0350 b1ac6df89ab5662ed680b7a38aaf0883 152 Pfam PF02050 Flagellar FliJ protein 21 140 6.7E-23 T 14-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 Tharo_0350 b1ac6df89ab5662ed680b7a38aaf0883 152 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 6 144 7.5E-21 T 14-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 Tharo_1333 8a692ae500ec556483b7f23fb21fe8cd 281 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 33 272 2.0E-74 T 14-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 Tharo_1333 8a692ae500ec556483b7f23fb21fe8cd 281 Gene3D G3DSA:3.40.50.150 1 280 5.2E-110 T 14-10-2018 Tharo_1333 8a692ae500ec556483b7f23fb21fe8cd 281 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 268 40.782 T 14-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 Tharo_1333 8a692ae500ec556483b7f23fb21fe8cd 281 SUPERFAMILY SSF53335 9 279 3.7E-92 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_2844 c8aaa9f7557e89be9aed24b54f2e0065 705 Pfam PF07715 TonB-dependent Receptor Plug Domain 54 163 5.7E-21 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain Tharo_2844 c8aaa9f7557e89be9aed24b54f2e0065 705 Gene3D G3DSA:2.170.130.10 36 173 2.4E-24 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Tharo_2844 c8aaa9f7557e89be9aed24b54f2e0065 705 SUPERFAMILY SSF56935 34 705 1.78E-113 T 14-10-2018 Tharo_2844 c8aaa9f7557e89be9aed24b54f2e0065 705 Gene3D G3DSA:2.40.170.20 181 705 7.4E-100 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Tharo_2844 c8aaa9f7557e89be9aed24b54f2e0065 705 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 688 705 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site Tharo_2844 c8aaa9f7557e89be9aed24b54f2e0065 705 Pfam PF00593 TonB dependent receptor 257 704 2.6E-48 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Tharo_2002 c40aa380cbf45b3889a6f20a5ea590b3 698 Gene3D G3DSA:3.10.20.30 39 143 1.8E-16 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Tharo_2002 c40aa380cbf45b3889a6f20a5ea590b3 698 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 48 106 9.8E-9 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Tharo_2002 c40aa380cbf45b3889a6f20a5ea590b3 698 Pfam PF14574 Domain of unknown function (DUF4445) 266 666 2.6E-126 T 14-10-2018 IPR027980 Protein of unknown function DUF4445 Tharo_2002 c40aa380cbf45b3889a6f20a5ea590b3 698 Gene3D G3DSA:3.30.420.480 264 446 5.5E-49 T 14-10-2018 Tharo_2002 c40aa380cbf45b3889a6f20a5ea590b3 698 SUPERFAMILY SSF53067 268 592 2.43E-10 T 14-10-2018 Tharo_2002 c40aa380cbf45b3889a6f20a5ea590b3 698 SUPERFAMILY SSF54292 35 135 4.98E-16 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Tharo_0098 3fcca528f6328410b664a5931dd7011f 917 Pfam PF01568 Molydopterin dinucleotide binding domain 810 867 1.7E-10 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 Tharo_0098 3fcca528f6328410b664a5931dd7011f 917 Gene3D G3DSA:2.40.40.20 753 916 1.1E-19 T 14-10-2018 Tharo_0098 3fcca528f6328410b664a5931dd7011f 917 Gene3D G3DSA:3.40.228.10 174 469 1.6E-37 T 14-10-2018 Tharo_0098 3fcca528f6328410b664a5931dd7011f 917 SUPERFAMILY SSF50692 780 910 2.71E-16 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Tharo_0098 3fcca528f6328410b664a5931dd7011f 917 Gene3D G3DSA:2.20.25.90 3 70 3.1E-7 T 14-10-2018 Tharo_0098 3fcca528f6328410b664a5931dd7011f 917 Pfam PF00384 Molybdopterin oxidoreductase 70 628 8.0E-21 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_0098 3fcca528f6328410b664a5931dd7011f 917 SUPERFAMILY SSF53706 10 622 4.35E-114 T 14-10-2018 Tharo_0098 3fcca528f6328410b664a5931dd7011f 917 Gene3D G3DSA:3.40.50.740 71 173 2.0E-10 T 14-10-2018 Tharo_0098 3fcca528f6328410b664a5931dd7011f 917 Gene3D G3DSA:3.40.50.740 479 643 1.2E-16 T 14-10-2018 Tharo_0485 b3a051967b2a1f39907618b48e6db2b6 50 PIRSF PIRSF000071 1 50 2.3E-23 T 14-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 Tharo_0485 b3a051967b2a1f39907618b48e6db2b6 50 Gene3D G3DSA:2.20.28.10 1 50 4.8E-25 T 14-10-2018 Tharo_0485 b3a051967b2a1f39907618b48e6db2b6 50 Pfam PF00301 Rubredoxin 1 45 5.3E-22 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 Tharo_0485 b3a051967b2a1f39907618b48e6db2b6 50 SUPERFAMILY SSF57802 1 49 4.71E-20 T 14-10-2018 Tharo_1352 e50d8605349b87d4c685a3d4804d75b8 962 Pfam PF00009 Elongation factor Tu GTP binding domain 467 623 1.5E-34 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_1352 e50d8605349b87d4c685a3d4804d75b8 962 SUPERFAMILY SSF46955 3 51 3.3E-10 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily Tharo_1352 e50d8605349b87d4c685a3d4804d75b8 962 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 960 17.5 T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 Tharo_1352 e50d8605349b87d4c685a3d4804d75b8 962 Gene3D G3DSA:2.40.30.10 634 752 2.2E-38 T 14-10-2018 Tharo_1352 e50d8605349b87d4c685a3d4804d75b8 962 Pfam PF11987 Translation-initiation factor 2 747 852 3.8E-38 T 14-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 Tharo_1352 e50d8605349b87d4c685a3d4804d75b8 962 Gene3D G3DSA:3.40.50.10050 756 863 1.9E-38 T 14-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily Tharo_1352 e50d8605349b87d4c685a3d4804d75b8 962 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 380 962 5.9E-263 T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 Tharo_1352 e50d8605349b87d4c685a3d4804d75b8 962 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 466 621 9.7E-32 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Tharo_1352 e50d8605349b87d4c685a3d4804d75b8 962 SUPERFAMILY SSF50447 864 960 8.32E-34 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Tharo_1352 e50d8605349b87d4c685a3d4804d75b8 962 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 60 98 2.1E-15 T 14-10-2018 IPR013575 Initiation factor 2 associated domain, bacterial Tharo_1352 e50d8605349b87d4c685a3d4804d75b8 962 ProSitePatterns PS01176 Initiation factor 2 signature. 913 935 - T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 Tharo_1352 e50d8605349b87d4c685a3d4804d75b8 962 SUPERFAMILY SSF52540 448 629 1.74E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1352 e50d8605349b87d4c685a3d4804d75b8 962 SUPERFAMILY SSF50447 635 715 4.86E-25 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Tharo_1352 e50d8605349b87d4c685a3d4804d75b8 962 Gene3D G3DSA:2.40.30.10 864 961 4.2E-33 T 14-10-2018 Tharo_1352 e50d8605349b87d4c685a3d4804d75b8 962 SUPERFAMILY SSF52156 740 869 1.11E-38 T 14-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily Tharo_1352 e50d8605349b87d4c685a3d4804d75b8 962 Gene3D G3DSA:3.40.50.300 459 633 2.8E-69 T 14-10-2018 Tharo_1352 e50d8605349b87d4c685a3d4804d75b8 962 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 385 436 4.0E-15 T 14-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal Tharo_1352 e50d8605349b87d4c685a3d4804d75b8 962 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 51 6.6E-8 T 14-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal Tharo_3204 c71672e46590edd56cece3412e20e5a7 300 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 11 279 6.0E-37 T 14-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 Tharo_3204 c71672e46590edd56cece3412e20e5a7 300 PIRSF PIRSF026649 4 289 1.4E-76 T 14-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 Tharo_2310 4a6d8c7f8d04e0154af28f1dd665b14c 84 TIGRFAM TIGR03647 Na_symport_sm: putative solute:sodium symporter small subunit 8 83 1.1E-32 T 14-10-2018 IPR019886 Sodium symporter small subunit, predicted Tharo_2310 4a6d8c7f8d04e0154af28f1dd665b14c 84 Pfam PF13937 Domain of unknown function (DUF4212) 6 82 5.1E-32 T 14-10-2018 IPR019886 Sodium symporter small subunit, predicted Tharo_3155 16a2f495a0d50cf52aada699c351c1e7 225 SUPERFAMILY SSF161098 5 215 1.7E-46 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_3155 16a2f495a0d50cf52aada699c351c1e7 225 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 12 216 3.9E-71 T 14-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 Tharo_3155 16a2f495a0d50cf52aada699c351c1e7 225 Gene3D G3DSA:1.10.3720.10 2 221 9.4E-53 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_3155 16a2f495a0d50cf52aada699c351c1e7 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 219 4.4E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Tharo_1482 09b365453a070739d0d35fc165c9f449 236 Gene3D G3DSA:1.10.1060.10 106 236 5.5E-56 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Tharo_1482 09b365453a070739d0d35fc165c9f449 236 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 8 110 2.0E-31 T 14-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_1482 09b365453a070739d0d35fc165c9f449 236 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 10 228 1.7E-83 T 14-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_1482 09b365453a070739d0d35fc165c9f449 236 Pfam PF13534 4Fe-4S dicluster domain 146 219 5.8E-10 T 14-10-2018 Tharo_1482 09b365453a070739d0d35fc165c9f449 236 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 147 158 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_1482 09b365453a070739d0d35fc165c9f449 236 SUPERFAMILY SSF46548 106 234 4.88E-37 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Tharo_1482 09b365453a070739d0d35fc165c9f449 236 SUPERFAMILY SSF54292 1 105 1.17E-27 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Tharo_1482 09b365453a070739d0d35fc165c9f449 236 Gene3D G3DSA:3.10.20.30 1 105 3.1E-35 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Tharo_0677 50400c1a3192522968e32f1a468147e3 920 Pfam PF00005 ABC transporter 292 435 1.5E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_0677 50400c1a3192522968e32f1a468147e3 920 SUPERFAMILY SSF52540 12 237 4.05E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0677 50400c1a3192522968e32f1a468147e3 920 Pfam PF00005 ABC transporter 26 173 1.1E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_0677 50400c1a3192522968e32f1a468147e3 920 Gene3D G3DSA:3.40.50.300 9 267 1.8E-60 T 14-10-2018 Tharo_0677 50400c1a3192522968e32f1a468147e3 920 SMART SM00382 35 256 7.4E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0677 50400c1a3192522968e32f1a468147e3 920 SMART SM00382 300 485 1.5E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0677 50400c1a3192522968e32f1a468147e3 920 Pfam PF12698 ABC-2 family transporter protein 579 912 7.3E-39 T 14-10-2018 Tharo_0677 50400c1a3192522968e32f1a468147e3 920 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_0677 50400c1a3192522968e32f1a468147e3 920 Gene3D G3DSA:3.40.50.300 270 514 2.1E-62 T 14-10-2018 Tharo_0677 50400c1a3192522968e32f1a468147e3 920 SUPERFAMILY SSF52540 275 496 4.99E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2956 ce1d9da54be5d0e1738f45602a4479a0 587 Pfam PF05746 DALR anticodon binding domain 470 587 2.1E-36 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 Tharo_2956 ce1d9da54be5d0e1738f45602a4479a0 587 SUPERFAMILY SSF52374 115 480 1.44E-87 T 14-10-2018 Tharo_2956 ce1d9da54be5d0e1738f45602a4479a0 587 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 8 90 2.3E-23 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Tharo_2956 ce1d9da54be5d0e1738f45602a4479a0 587 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 12 587 1.2E-126 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Tharo_2956 ce1d9da54be5d0e1738f45602a4479a0 587 Hamap MF_00123 Arginine--tRNA ligase [argS]. 7 587 25.846 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Tharo_2956 ce1d9da54be5d0e1738f45602a4479a0 587 Gene3D G3DSA:3.30.1360.70 4 107 2.9E-23 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 Tharo_2956 ce1d9da54be5d0e1738f45602a4479a0 587 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 128 137 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_2956 ce1d9da54be5d0e1738f45602a4479a0 587 SUPERFAMILY SSF47323 465 587 4.19E-36 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_2956 ce1d9da54be5d0e1738f45602a4479a0 587 Gene3D G3DSA:1.10.730.10 465 587 1.4E-35 T 14-10-2018 Tharo_2956 ce1d9da54be5d0e1738f45602a4479a0 587 Pfam PF00750 tRNA synthetases class I (R) 303 435 1.4E-11 T 14-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 Tharo_2956 ce1d9da54be5d0e1738f45602a4479a0 587 Pfam PF00750 tRNA synthetases class I (R) 99 174 5.1E-11 T 14-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 Tharo_2956 ce1d9da54be5d0e1738f45602a4479a0 587 SMART SM01016 7 90 1.1E-32 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Tharo_2956 ce1d9da54be5d0e1738f45602a4479a0 587 SMART SM00836 470 587 1.1E-50 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 Tharo_2956 ce1d9da54be5d0e1738f45602a4479a0 587 SUPERFAMILY SSF55190 8 110 1.83E-22 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 Tharo_2956 ce1d9da54be5d0e1738f45602a4479a0 587 PRINTS PR01038 Arginyl-tRNA synthetase signature 339 360 1.8E-21 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Tharo_2956 ce1d9da54be5d0e1738f45602a4479a0 587 PRINTS PR01038 Arginyl-tRNA synthetase signature 118 133 1.8E-21 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Tharo_2956 ce1d9da54be5d0e1738f45602a4479a0 587 PRINTS PR01038 Arginyl-tRNA synthetase signature 133 149 1.8E-21 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Tharo_2956 ce1d9da54be5d0e1738f45602a4479a0 587 PRINTS PR01038 Arginyl-tRNA synthetase signature 157 170 1.8E-21 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Tharo_1453 7c6c33fcb68ee2543505ca1c7bf41fdf 235 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_1453 7c6c33fcb68ee2543505ca1c7bf41fdf 235 Pfam PF00005 ABC transporter 36 184 1.0E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_1453 7c6c33fcb68ee2543505ca1c7bf41fdf 235 Gene3D G3DSA:3.40.50.300 14 235 4.8E-61 T 14-10-2018 Tharo_1453 7c6c33fcb68ee2543505ca1c7bf41fdf 235 TIGRFAM TIGR02211 LolD_lipo_ex: lipoprotein releasing system, ATP-binding protein 16 234 1.3E-97 T 14-10-2018 IPR011924 Lipoprotein releasing system, ATP-binding protein GO:0005524|GO:0016020|GO:0044873 Tharo_1453 7c6c33fcb68ee2543505ca1c7bf41fdf 235 SMART SM00382 45 233 4.3E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1453 7c6c33fcb68ee2543505ca1c7bf41fdf 235 SUPERFAMILY SSF52540 17 234 3.8E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3095 e450aaff1aa08f6fb3e49e8c8a361da9 401 Gene3D G3DSA:3.40.50.2300 29 337 3.1E-73 T 14-10-2018 Tharo_3095 e450aaff1aa08f6fb3e49e8c8a361da9 401 Gene3D G3DSA:3.40.50.2300 150 278 3.1E-73 T 14-10-2018 Tharo_3095 e450aaff1aa08f6fb3e49e8c8a361da9 401 Pfam PF13458 Periplasmic binding protein 28 342 3.0E-45 T 14-10-2018 IPR028081 Leucine-binding protein domain Tharo_3095 e450aaff1aa08f6fb3e49e8c8a361da9 401 SUPERFAMILY SSF53822 20 393 1.71E-73 T 14-10-2018 IPR028082 Periplasmic binding protein-like I Tharo_1911 01c22cff4e44bc0b933278ecefe58e87 245 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 1 240 54.012 T 14-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1911 01c22cff4e44bc0b933278ecefe58e87 245 Gene3D G3DSA:3.20.20.70 2 245 6.0E-88 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_1911 01c22cff4e44bc0b933278ecefe58e87 245 ProSitePatterns PS00171 Triosephosphate isomerase active site. 158 168 - T 14-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1911 01c22cff4e44bc0b933278ecefe58e87 245 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 4 231 4.1E-54 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1911 01c22cff4e44bc0b933278ecefe58e87 245 Pfam PF00121 Triosephosphate isomerase 4 238 5.0E-78 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1911 01c22cff4e44bc0b933278ecefe58e87 245 SUPERFAMILY SSF51351 3 242 2.62E-82 T 14-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1257 ac88fa1bb932ad6d155a58e5b23e55a4 163 SUPERFAMILY SSF54637 14 136 2.0E-29 T 14-10-2018 IPR029069 HotDog domain superfamily Tharo_1257 ac88fa1bb932ad6d155a58e5b23e55a4 163 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 33 142 6.0E-24 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 Tharo_1257 ac88fa1bb932ad6d155a58e5b23e55a4 163 Pfam PF03061 Thioesterase superfamily 61 135 3.2E-13 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 Tharo_1257 ac88fa1bb932ad6d155a58e5b23e55a4 163 TIGRFAM TIGR02286 PaaD: phenylacetic acid degradation protein PaaD 32 143 5.1E-46 T 14-10-2018 IPR011973 Phenylacetic acid degradation protein PaaD GO:0016790 Tharo_1257 ac88fa1bb932ad6d155a58e5b23e55a4 163 Gene3D G3DSA:3.10.129.10 13 159 8.0E-49 T 14-10-2018 Tharo_0270 6e6b90f7dd0742be496a483d249cf500 353 Pfam PF00842 Alanine racemase, C-terminal domain 229 346 3.2E-38 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Tharo_0270 6e6b90f7dd0742be496a483d249cf500 353 SUPERFAMILY SSF51419 8 230 6.15E-70 T 14-10-2018 IPR029066 PLP-binding barrel Tharo_0270 6e6b90f7dd0742be496a483d249cf500 353 TIGRFAM TIGR00492 alr: alanine racemase 3 346 1.1E-109 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Tharo_0270 6e6b90f7dd0742be496a483d249cf500 353 Hamap MF_01201 Alanine racemase. 1 352 34.99 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Tharo_0270 6e6b90f7dd0742be496a483d249cf500 353 Gene3D G3DSA:3.20.20.10 10 216 5.3E-126 T 14-10-2018 IPR029066 PLP-binding barrel Tharo_0270 6e6b90f7dd0742be496a483d249cf500 353 SUPERFAMILY SSF50621 223 346 5.58E-42 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Tharo_0270 6e6b90f7dd0742be496a483d249cf500 353 Pfam PF01168 Alanine racemase, N-terminal domain 8 218 2.9E-72 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Tharo_0270 6e6b90f7dd0742be496a483d249cf500 353 PRINTS PR00992 Alanine racemase signature 25 41 9.7E-67 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Tharo_0270 6e6b90f7dd0742be496a483d249cf500 353 PRINTS PR00992 Alanine racemase signature 120 132 9.7E-67 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Tharo_0270 6e6b90f7dd0742be496a483d249cf500 353 PRINTS PR00992 Alanine racemase signature 262 277 9.7E-67 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Tharo_0270 6e6b90f7dd0742be496a483d249cf500 353 PRINTS PR00992 Alanine racemase signature 245 260 9.7E-67 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Tharo_0270 6e6b90f7dd0742be496a483d249cf500 353 PRINTS PR00992 Alanine racemase signature 154 165 9.7E-67 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Tharo_0270 6e6b90f7dd0742be496a483d249cf500 353 PRINTS PR00992 Alanine racemase signature 335 348 9.7E-67 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Tharo_0270 6e6b90f7dd0742be496a483d249cf500 353 PRINTS PR00992 Alanine racemase signature 60 78 9.7E-67 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Tharo_0270 6e6b90f7dd0742be496a483d249cf500 353 PRINTS PR00992 Alanine racemase signature 191 218 9.7E-67 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Tharo_0270 6e6b90f7dd0742be496a483d249cf500 353 PRINTS PR00992 Alanine racemase signature 283 300 9.7E-67 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Tharo_0270 6e6b90f7dd0742be496a483d249cf500 353 SMART SM01005 229 352 1.6E-59 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Tharo_0270 6e6b90f7dd0742be496a483d249cf500 353 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 30 40 - T 14-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Tharo_0270 6e6b90f7dd0742be496a483d249cf500 353 Gene3D G3DSA:2.40.37.10 8 347 5.3E-126 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Tharo_3002 0f99a4b45aee4c7cc055a2e73311229b 150 Gene3D G3DSA:3.10.450.50 25 147 1.2E-12 T 14-10-2018 Tharo_3002 0f99a4b45aee4c7cc055a2e73311229b 150 SUPERFAMILY SSF54427 27 142 1.34E-10 T 14-10-2018 IPR032710 NTF2-like domain superfamily Tharo_3002 0f99a4b45aee4c7cc055a2e73311229b 150 Pfam PF13474 SnoaL-like domain 36 141 3.5E-6 T 14-10-2018 IPR037401 SnoaL-like domain Tharo_2003 e6f9c8afc1137e97a4709a81bfa0cdc9 300 SUPERFAMILY SSF51717 16 280 1.7E-28 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_2003 e6f9c8afc1137e97a4709a81bfa0cdc9 300 Pfam PF00809 Pterin binding enzyme 21 258 5.5E-10 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_2003 e6f9c8afc1137e97a4709a81bfa0cdc9 300 Gene3D G3DSA:3.20.20.20 13 290 5.3E-47 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_0185 e6f9c8afc1137e97a4709a81bfa0cdc9 300 SUPERFAMILY SSF51717 16 280 1.7E-28 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_0185 e6f9c8afc1137e97a4709a81bfa0cdc9 300 Pfam PF00809 Pterin binding enzyme 21 258 5.5E-10 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_0185 e6f9c8afc1137e97a4709a81bfa0cdc9 300 Gene3D G3DSA:3.20.20.20 13 290 5.3E-47 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_1011 2cca4d8e072f0c122e7f2390310f660f 560 SMART SM00332 1 229 1.1E-21 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Tharo_1011 2cca4d8e072f0c122e7f2390310f660f 560 Gene3D G3DSA:3.30.200.20 245 345 1.0E-42 T 14-10-2018 Tharo_1011 2cca4d8e072f0c122e7f2390310f660f 560 SMART SM00220 275 512 6.6E-12 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Tharo_1011 2cca4d8e072f0c122e7f2390310f660f 560 SUPERFAMILY SSF56112 262 510 1.12E-42 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Tharo_1011 2cca4d8e072f0c122e7f2390310f660f 560 SMART SM00331 18 231 6.4E-26 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Tharo_1011 2cca4d8e072f0c122e7f2390310f660f 560 SUPERFAMILY SSF81606 4 230 2.09E-54 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Tharo_1011 2cca4d8e072f0c122e7f2390310f660f 560 Pfam PF13672 Protein phosphatase 2C 30 203 7.5E-16 T 14-10-2018 Tharo_1011 2cca4d8e072f0c122e7f2390310f660f 560 Gene3D G3DSA:3.60.40.10 1 231 1.3E-52 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Tharo_1011 2cca4d8e072f0c122e7f2390310f660f 560 Pfam PF00069 Protein kinase domain 332 462 3.7E-26 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Tharo_1011 2cca4d8e072f0c122e7f2390310f660f 560 Gene3D G3DSA:1.10.510.10 346 515 1.0E-42 T 14-10-2018 Tharo_1033 98e9ed562129cba3f44cecaadfa1bc61 147 Pfam PF04386 Stringent starvation protein B 5 147 2.4E-36 T 14-10-2018 IPR007481 Stringent starvation protein B Tharo_1033 98e9ed562129cba3f44cecaadfa1bc61 147 Gene3D G3DSA:2.30.30.220 1 125 1.2E-45 T 14-10-2018 IPR036760 SspB-like superfamily Tharo_1033 98e9ed562129cba3f44cecaadfa1bc61 147 PIRSF PIRSF005276 1 147 1.1E-49 T 14-10-2018 IPR007481 Stringent starvation protein B Tharo_1033 98e9ed562129cba3f44cecaadfa1bc61 147 SUPERFAMILY SSF101738 2 107 6.15E-43 T 14-10-2018 IPR036760 SspB-like superfamily Tharo_1146 21d137269d2d881303e44c3c2a65d603 513 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 14 189 5.7E-62 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 Tharo_1146 21d137269d2d881303e44c3c2a65d603 513 Gene3D G3DSA:3.30.750.190 299 423 4.6E-92 T 14-10-2018 Tharo_1146 21d137269d2d881303e44c3c2a65d603 513 SUPERFAMILY SSF48179 426 509 3.91E-18 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Tharo_1146 21d137269d2d881303e44c3c2a65d603 513 Gene3D G3DSA:3.40.50.720 9 196 1.2E-67 T 14-10-2018 Tharo_1146 21d137269d2d881303e44c3c2a65d603 513 Gene3D G3DSA:1.10.1040.50 197 506 4.6E-92 T 14-10-2018 Tharo_1146 21d137269d2d881303e44c3c2a65d603 513 SUPERFAMILY SSF51735 12 193 2.59E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1146 21d137269d2d881303e44c3c2a65d603 513 TIGRFAM TIGR02279 PaaC-3OHAcCoADH: 3-hydroxyacyl-CoA dehydrogenase PaaC 8 513 6.6E-238 T 14-10-2018 IPR011967 3-hydroxyacyl-CoA dehydrogenase PaaC GO:0008691|GO:0010124 Tharo_1146 21d137269d2d881303e44c3c2a65d603 513 SUPERFAMILY SSF48179 193 300 1.7E-31 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Tharo_1146 21d137269d2d881303e44c3c2a65d603 513 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 194 291 2.0E-31 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 Tharo_1146 21d137269d2d881303e44c3c2a65d603 513 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 426 505 1.5E-14 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 Tharo_2249 44d7cb22c5d6dda61b5f386a68129248 952 SMART SM00283 646 893 2.7E-90 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_2249 44d7cb22c5d6dda61b5f386a68129248 952 Gene3D G3DSA:1.10.287.950 595 895 7.7E-84 T 14-10-2018 Tharo_2249 44d7cb22c5d6dda61b5f386a68129248 952 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 821 850 7.1E-56 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_2249 44d7cb22c5d6dda61b5f386a68129248 952 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 744 771 7.1E-56 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_2249 44d7cb22c5d6dda61b5f386a68129248 952 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 773 802 7.1E-56 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_2249 44d7cb22c5d6dda61b5f386a68129248 952 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 667 696 7.1E-56 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_2249 44d7cb22c5d6dda61b5f386a68129248 952 Gene3D G3DSA:3.30.450.20 429 549 2.9E-25 T 14-10-2018 Tharo_2249 44d7cb22c5d6dda61b5f386a68129248 952 Gene3D G3DSA:3.30.450.20 16 139 1.0E-26 T 14-10-2018 Tharo_2249 44d7cb22c5d6dda61b5f386a68129248 952 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 705 861 5.1E-52 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_2249 44d7cb22c5d6dda61b5f386a68129248 952 SUPERFAMILY SSF58104 613 894 3.14E-72 T 14-10-2018 Tharo_2249 44d7cb22c5d6dda61b5f386a68129248 952 Pfam PF08447 PAS fold 31 113 3.2E-15 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 Tharo_2249 44d7cb22c5d6dda61b5f386a68129248 952 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 24 115 2.5E-13 T 14-10-2018 IPR000014 PAS domain Tharo_2249 44d7cb22c5d6dda61b5f386a68129248 952 SUPERFAMILY SSF158472 371 418 6.41E-7 T 14-10-2018 Tharo_2249 44d7cb22c5d6dda61b5f386a68129248 952 SUPERFAMILY SSF55785 20 114 4.71E-27 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_2249 44d7cb22c5d6dda61b5f386a68129248 952 Gene3D G3DSA:1.20.1480.50 331 427 3.2E-9 T 14-10-2018 Tharo_2249 44d7cb22c5d6dda61b5f386a68129248 952 SMART SM00086 80 121 1.4E-4 T 14-10-2018 IPR001610 PAC motif Tharo_2249 44d7cb22c5d6dda61b5f386a68129248 952 SMART SM00304 593 645 0.68 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_2249 44d7cb22c5d6dda61b5f386a68129248 952 SMART SM00304 371 423 5.3E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 ProSitePatterns PS00177 DNA topoisomerase II signature. 434 442 - T 14-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 SUPERFAMILY SSF56719 406 653 2.62E-72 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 Gene3D G3DSA:3.40.50.670 408 655 2.1E-80 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 Gene3D G3DSA:3.30.230.10 229 407 1.0E-43 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 Pfam PF00204 DNA gyrase B 231 403 1.9E-37 T 14-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 589 652 1.8E-22 T 14-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 Gene3D G3DSA:3.30.565.10 8 220 3.8E-66 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 PRINTS PR01098 Topoisomerase IV subunit B signature 32 45 3.1E-31 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 PRINTS PR01098 Topoisomerase IV subunit B signature 356 379 3.1E-31 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 PRINTS PR01098 Topoisomerase IV subunit B signature 312 328 3.1E-31 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 PRINTS PR01098 Topoisomerase IV subunit B signature 329 344 3.1E-31 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 PRINTS PR01098 Topoisomerase IV subunit B signature 380 405 3.1E-31 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 PRINTS PR01098 Topoisomerase IV subunit B signature 466 487 3.1E-31 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 PRINTS PR01098 Topoisomerase IV subunit B signature 184 201 3.1E-31 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 PRINTS PR00418 DNA topoisomerase II family signature 539 551 6.3E-63 T 14-10-2018 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 PRINTS PR00418 DNA topoisomerase II family signature 284 297 6.3E-63 T 14-10-2018 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 PRINTS PR00418 DNA topoisomerase II family signature 519 536 6.3E-63 T 14-10-2018 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 PRINTS PR00418 DNA topoisomerase II family signature 37 52 6.3E-63 T 14-10-2018 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 PRINTS PR00418 DNA topoisomerase II family signature 501 517 6.3E-63 T 14-10-2018 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 PRINTS PR00418 DNA topoisomerase II family signature 592 608 6.3E-63 T 14-10-2018 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 PRINTS PR00418 DNA topoisomerase II family signature 432 446 6.3E-63 T 14-10-2018 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 PRINTS PR00418 DNA topoisomerase II family signature 119 133 6.3E-63 T 14-10-2018 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 PRINTS PR00418 DNA topoisomerase II family signature 72 85 6.3E-63 T 14-10-2018 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 SMART SM00387 33 183 1.8E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 Pfam PF01751 Toprim domain 431 545 1.1E-12 T 14-10-2018 IPR006171 TOPRIM domain Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 SUPERFAMILY SSF54211 231 405 2.47E-35 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 8 660 43.362 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 39 180 6.5E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 SMART SM00433 40 656 8.1E-186 T 14-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Tharo_1321 f79e7671415fbb1d307cb725e8e7ef10 662 SUPERFAMILY SSF55874 10 213 9.45E-56 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_0920 2c5d572f37016c7f7be56dc9e8b72685 466 SUPERFAMILY SSF53244 325 456 7.53E-38 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Tharo_0920 2c5d572f37016c7f7be56dc9e8b72685 466 Pfam PF02875 Mur ligase family, glutamate ligase domain 325 404 2.3E-11 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Tharo_0920 2c5d572f37016c7f7be56dc9e8b72685 466 Gene3D G3DSA:3.40.1390.10 1 85 6.0E-21 T 14-10-2018 Tharo_0920 2c5d572f37016c7f7be56dc9e8b72685 466 Pfam PF01225 Mur ligase family, catalytic domain 25 100 3.1E-12 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 Tharo_0920 2c5d572f37016c7f7be56dc9e8b72685 466 SUPERFAMILY SSF53623 105 323 1.96E-51 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Tharo_0920 2c5d572f37016c7f7be56dc9e8b72685 466 Gene3D G3DSA:3.40.1190.10 86 321 1.8E-77 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Tharo_0920 2c5d572f37016c7f7be56dc9e8b72685 466 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 2 457 33.365 T 14-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Tharo_0920 2c5d572f37016c7f7be56dc9e8b72685 466 SUPERFAMILY SSF63418 17 100 9.81E-23 T 14-10-2018 IPR035911 MurE/MurF, N-terminal Tharo_0920 2c5d572f37016c7f7be56dc9e8b72685 466 Gene3D G3DSA:3.90.190.20 324 460 1.4E-40 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Tharo_0920 2c5d572f37016c7f7be56dc9e8b72685 466 Pfam PF08245 Mur ligase middle domain 110 304 3.8E-44 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Tharo_0920 2c5d572f37016c7f7be56dc9e8b72685 466 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 30 456 2.6E-136 T 14-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Tharo_3066 269f233471dc7605433dc2a847972a8c 548 Pfam PF13188 PAS domain 187 223 1.3E-5 T 14-10-2018 IPR000014 PAS domain Tharo_3066 269f233471dc7605433dc2a847972a8c 548 Gene3D G3DSA:3.30.450.20 22 139 2.0E-26 T 14-10-2018 Tharo_3066 269f233471dc7605433dc2a847972a8c 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 547 2.6E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3066 269f233471dc7605433dc2a847972a8c 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 481 495 2.6E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3066 269f233471dc7605433dc2a847972a8c 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 499 509 2.6E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3066 269f233471dc7605433dc2a847972a8c 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 510 528 2.6E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3066 269f233471dc7605433dc2a847972a8c 548 Gene3D G3DSA:1.10.287.130 332 393 1.0E-8 T 14-10-2018 Tharo_3066 269f233471dc7605433dc2a847972a8c 548 SUPERFAMILY SSF55785 173 303 2.62E-11 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_3066 269f233471dc7605433dc2a847972a8c 548 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 442 547 4.4E-15 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_3066 269f233471dc7605433dc2a847972a8c 548 SUPERFAMILY SSF55785 42 144 2.39E-17 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_3066 269f233471dc7605433dc2a847972a8c 548 SUPERFAMILY SSF55874 395 548 2.62E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_3066 269f233471dc7605433dc2a847972a8c 548 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 25 142 1.2E-17 T 14-10-2018 IPR000014 PAS domain Tharo_3066 269f233471dc7605433dc2a847972a8c 548 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 184 310 2.9E-9 T 14-10-2018 IPR000014 PAS domain Tharo_3066 269f233471dc7605433dc2a847972a8c 548 Pfam PF13426 PAS domain 44 135 1.1E-8 T 14-10-2018 IPR000014 PAS domain Tharo_3066 269f233471dc7605433dc2a847972a8c 548 Gene3D G3DSA:3.30.565.10 395 548 2.6E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_3066 269f233471dc7605433dc2a847972a8c 548 SMART SM00091 187 255 0.14 T 14-10-2018 IPR000014 PAS domain Tharo_3066 269f233471dc7605433dc2a847972a8c 548 SMART SM00091 23 89 5.4 T 14-10-2018 IPR000014 PAS domain Tharo_3066 269f233471dc7605433dc2a847972a8c 548 SMART SM00387 438 548 4.6E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_3066 269f233471dc7605433dc2a847972a8c 548 Gene3D G3DSA:3.30.450.20 173 303 2.2E-14 T 14-10-2018 Tharo_3066 269f233471dc7605433dc2a847972a8c 548 SMART SM00086 95 136 0.0094 T 14-10-2018 IPR001610 PAC motif Tharo_3066 269f233471dc7605433dc2a847972a8c 548 SMART SM00086 264 305 420.0 T 14-10-2018 IPR001610 PAC motif Tharo_2255 0ad1c2c3e98086944de72c8cc9a3bd3f 1031 SMART SM00926 70 154 1.9E-12 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_2255 0ad1c2c3e98086944de72c8cc9a3bd3f 1031 SUPERFAMILY SSF53706 69 868 6.89E-110 T 14-10-2018 Tharo_2255 0ad1c2c3e98086944de72c8cc9a3bd3f 1031 Gene3D G3DSA:3.40.50.740 591 704 1.1E-10 T 14-10-2018 Tharo_2255 0ad1c2c3e98086944de72c8cc9a3bd3f 1031 Pfam PF01568 Molydopterin dinucleotide binding domain 912 975 8.9E-13 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 Tharo_2255 0ad1c2c3e98086944de72c8cc9a3bd3f 1031 Gene3D G3DSA:2.40.40.20 861 1008 1.5E-18 T 14-10-2018 Tharo_2255 0ad1c2c3e98086944de72c8cc9a3bd3f 1031 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 75 92 - T 14-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 Tharo_2255 0ad1c2c3e98086944de72c8cc9a3bd3f 1031 SUPERFAMILY SSF50692 886 1007 1.51E-22 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Tharo_2255 0ad1c2c3e98086944de72c8cc9a3bd3f 1031 Pfam PF00384 Molybdopterin oxidoreductase 281 690 1.4E-11 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_0928 1f3aebb44d1fa66eec8be858f62dbd00 409 SMART SM00842 9 195 5.1E-100 T 14-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 Tharo_0928 1f3aebb44d1fa66eec8be858f62dbd00 409 Pfam PF14450 Cell division protein FtsA 206 373 2.7E-25 T 14-10-2018 Tharo_0928 1f3aebb44d1fa66eec8be858f62dbd00 409 Gene3D G3DSA:3.90.640.10 234 299 1.2E-124 T 14-10-2018 Tharo_0928 1f3aebb44d1fa66eec8be858f62dbd00 409 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 8 375 2.3E-146 T 14-10-2018 IPR020823 Cell division protein FtsA Tharo_0928 1f3aebb44d1fa66eec8be858f62dbd00 409 PIRSF PIRSF003101 1 409 6.0E-153 T 14-10-2018 IPR020823 Cell division protein FtsA Tharo_0928 1f3aebb44d1fa66eec8be858f62dbd00 409 Gene3D G3DSA:3.30.420.40 12 371 1.2E-124 T 14-10-2018 Tharo_0928 1f3aebb44d1fa66eec8be858f62dbd00 409 Pfam PF14450 Cell division protein FtsA 10 191 2.0E-8 T 14-10-2018 Tharo_0928 1f3aebb44d1fa66eec8be858f62dbd00 409 Gene3D G3DSA:3.30.420.40 196 351 1.2E-124 T 14-10-2018 Tharo_0928 1f3aebb44d1fa66eec8be858f62dbd00 409 Pfam PF02491 SHS2 domain inserted in FTSA 84 161 1.6E-31 T 14-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 Tharo_0928 1f3aebb44d1fa66eec8be858f62dbd00 409 Gene3D G3DSA:3.30.1490.110 86 168 1.2E-124 T 14-10-2018 Tharo_0928 1f3aebb44d1fa66eec8be858f62dbd00 409 Hamap MF_02033 Cell division protein FtsA [ftsA]. 5 409 30.939 T 14-10-2018 IPR020823 Cell division protein FtsA Tharo_0928 1f3aebb44d1fa66eec8be858f62dbd00 409 SUPERFAMILY SSF53067 7 196 3.37E-58 T 14-10-2018 Tharo_0928 1f3aebb44d1fa66eec8be858f62dbd00 409 SUPERFAMILY SSF53067 197 376 4.6E-51 T 14-10-2018 Tharo_3159 4eac9b72daf67c5f658f0cc31df7834d 462 Gene3D G3DSA:1.10.10.60 413 454 5.9E-15 T 14-10-2018 Tharo_3159 4eac9b72daf67c5f658f0cc31df7834d 462 Gene3D G3DSA:3.40.50.300 130 308 9.0E-64 T 14-10-2018 Tharo_3159 4eac9b72daf67c5f658f0cc31df7834d 462 Pfam PF00158 Sigma-54 interaction domain 139 304 5.9E-67 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Tharo_3159 4eac9b72daf67c5f658f0cc31df7834d 462 Pfam PF02954 Bacterial regulatory protein, Fis family 417 455 2.8E-15 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_3159 4eac9b72daf67c5f658f0cc31df7834d 462 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 224 239 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Tharo_3159 4eac9b72daf67c5f658f0cc31df7834d 462 SUPERFAMILY SSF52540 138 381 4.67E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3159 4eac9b72daf67c5f658f0cc31df7834d 462 SUPERFAMILY SSF55785 16 131 1.12E-9 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_3159 4eac9b72daf67c5f658f0cc31df7834d 462 Gene3D G3DSA:3.30.450.20 14 129 2.2E-9 T 14-10-2018 Tharo_3159 4eac9b72daf67c5f658f0cc31df7834d 462 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 438 458 3.4E-9 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_3159 4eac9b72daf67c5f658f0cc31df7834d 462 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 421 438 3.4E-9 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_3159 4eac9b72daf67c5f658f0cc31df7834d 462 SUPERFAMILY SSF46689 351 455 3.29E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_3159 4eac9b72daf67c5f658f0cc31df7834d 462 Gene3D G3DSA:1.10.8.60 309 388 1.2E-21 T 14-10-2018 Tharo_3159 4eac9b72daf67c5f658f0cc31df7834d 462 SMART SM00382 158 301 1.1E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_3168 98b593c98124a1a5827c8b3a8f26344d 522 PIRSF PIRSF015855 3 399 1.1E-115 T 14-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 Tharo_3168 98b593c98124a1a5827c8b3a8f26344d 522 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 62 68 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Tharo_3168 98b593c98124a1a5827c8b3a8f26344d 522 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 58 72 4.3E-22 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Tharo_3168 98b593c98124a1a5827c8b3a8f26344d 522 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 340 360 4.3E-22 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Tharo_3168 98b593c98124a1a5827c8b3a8f26344d 522 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 93 113 4.3E-22 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Tharo_3168 98b593c98124a1a5827c8b3a8f26344d 522 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 298 315 4.3E-22 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Tharo_3168 98b593c98124a1a5827c8b3a8f26344d 522 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 317 335 4.3E-22 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Tharo_3168 98b593c98124a1a5827c8b3a8f26344d 522 SUPERFAMILY SSF53335 36 369 3.69E-79 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_3168 98b593c98124a1a5827c8b3a8f26344d 522 Pfam PF01555 DNA methylase 59 351 4.6E-57 T 14-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 Tharo_2936 6d02f4b3047ca4701c52bc4056a896b8 409 SUPERFAMILY SSF89796 7 405 2.22E-127 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily Tharo_2936 6d02f4b3047ca4701c52bc4056a896b8 409 Gene3D G3DSA:3.30.1540.10 238 334 4.1E-127 T 14-10-2018 Tharo_2936 6d02f4b3047ca4701c52bc4056a896b8 409 Pfam PF02515 CoA-transferase family III 9 383 8.6E-124 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 Tharo_2936 6d02f4b3047ca4701c52bc4056a896b8 409 Gene3D G3DSA:3.40.50.10540 9 400 4.1E-127 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily Tharo_0863 917d7cf212c15a22d0e50f9f34dbda10 359 SUPERFAMILY SSF56601 85 342 9.05E-53 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Tharo_0863 917d7cf212c15a22d0e50f9f34dbda10 359 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 105 325 4.2E-54 T 14-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 Tharo_0863 917d7cf212c15a22d0e50f9f34dbda10 359 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 210 223 2.9E-13 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 Tharo_0863 917d7cf212c15a22d0e50f9f34dbda10 359 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 183 200 2.9E-13 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 Tharo_0863 917d7cf212c15a22d0e50f9f34dbda10 359 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 133 144 2.9E-13 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 Tharo_0863 917d7cf212c15a22d0e50f9f34dbda10 359 Gene3D G3DSA:3.40.710.10 75 353 1.8E-60 T 14-10-2018 Tharo_2771 9d361becdfaf7574fc78cb80f05c181b 1108 SUPERFAMILY SSF52242 11 150 2.49E-42 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 Tharo_2771 9d361becdfaf7574fc78cb80f05c181b 1108 Pfam PF03308 ArgK protein 180 379 2.2E-42 T 14-10-2018 Tharo_2771 9d361becdfaf7574fc78cb80f05c181b 1108 Pfam PF02310 B12 binding domain 20 122 3.6E-14 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 Tharo_2771 9d361becdfaf7574fc78cb80f05c181b 1108 Pfam PF01642 Methylmalonyl-CoA mutase 584 1102 2.7E-139 T 14-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Tharo_2771 9d361becdfaf7574fc78cb80f05c181b 1108 Gene3D G3DSA:3.40.50.300 208 415 4.1E-57 T 14-10-2018 Tharo_2771 9d361becdfaf7574fc78cb80f05c181b 1108 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 18 145 2.1E-18 T 14-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Tharo_2771 9d361becdfaf7574fc78cb80f05c181b 1108 SUPERFAMILY SSF52540 135 471 2.58E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2771 9d361becdfaf7574fc78cb80f05c181b 1108 Gene3D G3DSA:3.40.50.280 14 157 6.2E-59 T 14-10-2018 Tharo_2771 9d361becdfaf7574fc78cb80f05c181b 1108 SUPERFAMILY SSF51703 551 1104 2.38E-145 T 14-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Tharo_2771 9d361becdfaf7574fc78cb80f05c181b 1108 Gene3D G3DSA:3.20.20.240 572 1104 1.3E-179 T 14-10-2018 Tharo_2771 9d361becdfaf7574fc78cb80f05c181b 1108 Hamap MF_02050 Fused isobutyryl-CoA mutase [icmF]. 18 1108 16.573 T 14-10-2018 IPR033669 Fused isobutyryl-CoA mutase GO:0003924|GO:0005525|GO:0006637|GO:0031419|GO:0034784|GO:0047727 Tharo_0182 bc1a40b5fb3e35cdd8c356a568c02de8 399 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 192 397 1.3E-20 T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 Tharo_0182 bc1a40b5fb3e35cdd8c356a568c02de8 399 SUPERFAMILY SSF51726 3 397 1.06E-36 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 Tharo_2257 b4fa8436985e622d2d5699c4267d13e7 250 Gene3D G3DSA:3.30.70.20 37 241 1.6E-66 T 14-10-2018 Tharo_2257 b4fa8436985e622d2d5699c4267d13e7 250 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 135 146 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_2257 b4fa8436985e622d2d5699c4267d13e7 250 SUPERFAMILY SSF54862 43 225 1.15E-69 T 14-10-2018 Tharo_2257 b4fa8436985e622d2d5699c4267d13e7 250 Pfam PF13247 4Fe-4S dicluster domain 97 190 3.6E-30 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_3271 915365990eb79ed60bedb21035ebe24e 350 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 219 285 3.7E-19 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Tharo_3271 915365990eb79ed60bedb21035ebe24e 350 Gene3D G3DSA:3.40.50.10490 1 189 8.4E-70 T 14-10-2018 Tharo_3271 915365990eb79ed60bedb21035ebe24e 350 SUPERFAMILY SSF53697 3 184 1.17E-50 T 14-10-2018 Tharo_3271 915365990eb79ed60bedb21035ebe24e 350 Pfam PF13580 SIS domain 6 142 1.4E-30 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Tharo_3271 915365990eb79ed60bedb21035ebe24e 350 SUPERFAMILY SSF52374 218 348 1.81E-25 T 14-10-2018 Tharo_3271 915365990eb79ed60bedb21035ebe24e 350 Gene3D G3DSA:3.40.50.620 202 350 2.2E-39 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_3271 915365990eb79ed60bedb21035ebe24e 350 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 1 185 35.801 T 14-10-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 Tharo_3271 915365990eb79ed60bedb21035ebe24e 350 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 209 349 1.8E-61 T 14-10-2018 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 Tharo_3271 915365990eb79ed60bedb21035ebe24e 350 Pfam PF01467 Cytidylyltransferase-like 222 312 2.8E-17 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Tharo_2735 1b766db4e4f7ddd8940454b17b08151e 143 SMART SM00649 9 141 4.0E-87 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 Tharo_2735 1b766db4e4f7ddd8940454b17b08151e 143 Gene3D G3DSA:1.10.10.2720 73 143 1.3E-29 T 14-10-2018 Tharo_2735 1b766db4e4f7ddd8940454b17b08151e 143 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 2.5E-66 T 14-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2735 1b766db4e4f7ddd8940454b17b08151e 143 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 5.6E-29 T 14-10-2018 IPR020784 Ribosomal protein L11, N-terminal Tharo_2735 1b766db4e4f7ddd8940454b17b08151e 143 Gene3D G3DSA:3.30.1550.10 2 72 2.1E-34 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily Tharo_2735 1b766db4e4f7ddd8940454b17b08151e 143 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 32.119 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 Tharo_2735 1b766db4e4f7ddd8940454b17b08151e 143 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 14-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2735 1b766db4e4f7ddd8940454b17b08151e 143 SUPERFAMILY SSF54747 3 73 3.27E-30 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily Tharo_2735 1b766db4e4f7ddd8940454b17b08151e 143 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 4.0E-16 T 14-10-2018 Tharo_2735 1b766db4e4f7ddd8940454b17b08151e 143 SUPERFAMILY SSF46906 68 141 3.4E-28 T 14-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily Tharo_2735 1b766db4e4f7ddd8940454b17b08151e 143 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 6.7E-27 T 14-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 Tharo_0885 87a46daf21ae910993354d2d3daac16b 578 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 353 552 3.2E-55 T 14-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Tharo_0885 87a46daf21ae910993354d2d3daac16b 578 Gene3D G3DSA:3.90.800.10 109 217 4.0E-102 T 14-10-2018 Tharo_0885 87a46daf21ae910993354d2d3daac16b 578 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 36 350 3.0E-101 T 14-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 Tharo_0885 87a46daf21ae910993354d2d3daac16b 578 SUPERFAMILY SSF52374 19 350 8.3E-95 T 14-10-2018 Tharo_0885 87a46daf21ae910993354d2d3daac16b 578 SUPERFAMILY SSF50715 353 572 1.57E-71 T 14-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Tharo_0885 87a46daf21ae910993354d2d3daac16b 578 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_0885 87a46daf21ae910993354d2d3daac16b 578 PRINTS PR00987 Glutamyl-tRNA synthetase signature 218 228 1.4E-9 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Tharo_0885 87a46daf21ae910993354d2d3daac16b 578 PRINTS PR00987 Glutamyl-tRNA synthetase signature 39 51 1.4E-9 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Tharo_0885 87a46daf21ae910993354d2d3daac16b 578 PRINTS PR00987 Glutamyl-tRNA synthetase signature 53 64 1.4E-9 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Tharo_0885 87a46daf21ae910993354d2d3daac16b 578 PRINTS PR00987 Glutamyl-tRNA synthetase signature 68 81 1.4E-9 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Tharo_0885 87a46daf21ae910993354d2d3daac16b 578 Gene3D G3DSA:3.40.50.620 37 256 4.0E-102 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_0885 87a46daf21ae910993354d2d3daac16b 578 Gene3D G3DSA:2.40.240.10 478 573 1.9E-34 T 14-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Tharo_0885 87a46daf21ae910993354d2d3daac16b 578 Gene3D G3DSA:2.40.240.10 361 477 4.3E-43 T 14-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Tharo_0885 87a46daf21ae910993354d2d3daac16b 578 Gene3D G3DSA:1.10.1160.10 274 352 9.7E-32 T 14-10-2018 IPR020061 Glutamine-tRNA ligase, alpha-bundle domain superfamily GO:0005524 Tharo_0885 87a46daf21ae910993354d2d3daac16b 578 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 36 575 2.8E-214 T 14-10-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Tharo_0885 87a46daf21ae910993354d2d3daac16b 578 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 573 52.315 T 14-10-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 Tharo_2690 3a981fc24042b627c3441cdb1ab9ab71 352 Gene3D G3DSA:2.40.30.170 42 274 4.1E-59 T 14-10-2018 Tharo_2690 3a981fc24042b627c3441cdb1ab9ab71 352 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 50 267 9.8E-21 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Tharo_2690 3a981fc24042b627c3441cdb1ab9ab71 352 Gene3D G3DSA:1.10.287.470 88 159 4.1E-59 T 14-10-2018 Tharo_2690 3a981fc24042b627c3441cdb1ab9ab71 352 Gene3D G3DSA:2.40.50.100 54 194 4.1E-59 T 14-10-2018 Tharo_2690 3a981fc24042b627c3441cdb1ab9ab71 352 Gene3D G3DSA:2.40.420.20 30 333 4.1E-59 T 14-10-2018 Tharo_2690 3a981fc24042b627c3441cdb1ab9ab71 352 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 29 334 1.2E-56 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Tharo_2690 3a981fc24042b627c3441cdb1ab9ab71 352 SUPERFAMILY SSF111369 45 271 4.97E-26 T 14-10-2018 Tharo_1062 2bc7a92ad5fcb4c5d27ea279ce510a90 409 PRINTS PR00812 Bacterial general secretion pathway protein F signature 71 83 2.5E-18 T 14-10-2018 IPR003004 GspF/PilC family Tharo_1062 2bc7a92ad5fcb4c5d27ea279ce510a90 409 PRINTS PR00812 Bacterial general secretion pathway protein F signature 170 198 2.5E-18 T 14-10-2018 IPR003004 GspF/PilC family Tharo_1062 2bc7a92ad5fcb4c5d27ea279ce510a90 409 PRINTS PR00812 Bacterial general secretion pathway protein F signature 390 409 2.5E-18 T 14-10-2018 IPR003004 GspF/PilC family Tharo_1062 2bc7a92ad5fcb4c5d27ea279ce510a90 409 PRINTS PR00812 Bacterial general secretion pathway protein F signature 374 388 2.5E-18 T 14-10-2018 IPR003004 GspF/PilC family Tharo_1062 2bc7a92ad5fcb4c5d27ea279ce510a90 409 Pfam PF00482 Type II secretion system (T2SS), protein F 279 401 1.3E-29 T 14-10-2018 IPR018076 Type II secretion system F domain Tharo_1062 2bc7a92ad5fcb4c5d27ea279ce510a90 409 Pfam PF00482 Type II secretion system (T2SS), protein F 75 198 1.7E-33 T 14-10-2018 IPR018076 Type II secretion system F domain Tharo_1062 2bc7a92ad5fcb4c5d27ea279ce510a90 409 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 170 198 - T 14-10-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 Tharo_1062 2bc7a92ad5fcb4c5d27ea279ce510a90 409 Gene3D G3DSA:1.20.81.30 262 372 5.6E-29 T 14-10-2018 Tharo_1062 2bc7a92ad5fcb4c5d27ea279ce510a90 409 Gene3D G3DSA:1.20.81.30 61 177 3.4E-33 T 14-10-2018 Tharo_1161 bb0bb1007957a612a7209201e3d5e969 480 Gene3D G3DSA:3.30.465.10 95 216 7.1E-44 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Tharo_1161 bb0bb1007957a612a7209201e3d5e969 480 Gene3D G3DSA:3.30.70.2740 341 427 1.1E-31 T 14-10-2018 Tharo_1161 bb0bb1007957a612a7209201e3d5e969 480 SUPERFAMILY SSF55103 220 468 8.83E-57 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 Tharo_1161 bb0bb1007957a612a7209201e3d5e969 480 Gene3D G3DSA:3.30.43.10 1 93 6.1E-27 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 Tharo_1161 bb0bb1007957a612a7209201e3d5e969 480 Gene3D G3DSA:3.30.70.2190 218 340 3.7E-35 T 14-10-2018 Tharo_1161 bb0bb1007957a612a7209201e3d5e969 480 Gene3D G3DSA:1.10.45.10 428 468 4.0E-17 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 Tharo_1161 bb0bb1007957a612a7209201e3d5e969 480 SUPERFAMILY SSF56176 3 215 6.54E-73 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Tharo_1161 bb0bb1007957a612a7209201e3d5e969 480 Pfam PF01565 FAD binding domain 40 177 6.3E-32 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Tharo_1161 bb0bb1007957a612a7209201e3d5e969 480 Pfam PF02913 FAD linked oxidases, C-terminal domain 219 467 5.6E-53 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 Tharo_2348 901a8772f01d0a62d6d595ac19c0202b 481 Gene3D G3DSA:3.30.2290.10 21 240 6.5E-18 T 14-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal Tharo_2348 901a8772f01d0a62d6d595ac19c0202b 481 PIRSF PIRSF004919 21 481 7.9E-139 T 14-10-2018 IPR025502 TldD Tharo_2348 901a8772f01d0a62d6d595ac19c0202b 481 Pfam PF01523 Putative modulator of DNA gyrase 40 332 1.8E-69 T 14-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 Tharo_2348 901a8772f01d0a62d6d595ac19c0202b 481 SUPERFAMILY SSF111283 26 480 3.66E-133 T 14-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 Tharo_1642 e7379b3cb23c7cf5a4a58a828f464418 687 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 670 687 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site Tharo_1642 e7379b3cb23c7cf5a4a58a828f464418 687 SUPERFAMILY SSF56935 34 687 7.47E-98 T 14-10-2018 Tharo_1642 e7379b3cb23c7cf5a4a58a828f464418 687 Gene3D G3DSA:2.40.170.20 156 687 4.1E-81 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Tharo_1642 e7379b3cb23c7cf5a4a58a828f464418 687 Gene3D G3DSA:2.170.130.10 31 150 3.9E-24 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Tharo_1642 e7379b3cb23c7cf5a4a58a828f464418 687 Pfam PF07715 TonB-dependent Receptor Plug Domain 62 145 4.8E-17 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain Tharo_1642 e7379b3cb23c7cf5a4a58a828f464418 687 Pfam PF00593 TonB dependent receptor 215 684 5.6E-45 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Tharo_3086 bc54567ae116befb6278de7cc5c76d45 410 SUPERFAMILY SSF89796 6 405 5.36E-89 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily Tharo_3086 bc54567ae116befb6278de7cc5c76d45 410 Pfam PF02515 CoA-transferase family III 8 382 3.1E-77 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 Tharo_3086 bc54567ae116befb6278de7cc5c76d45 410 Gene3D G3DSA:3.40.50.10540 8 399 8.2E-92 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily Tharo_3086 bc54567ae116befb6278de7cc5c76d45 410 Gene3D G3DSA:3.30.1540.10 228 333 8.2E-92 T 14-10-2018 Tharo_0862 9cfe842e8ed73002ad1e63d479a9362f 757 Gene3D G3DSA:3.40.50.10750 572 726 2.8E-84 T 14-10-2018 Tharo_0862 9cfe842e8ed73002ad1e63d479a9362f 757 Gene3D G3DSA:3.40.50.10950 445 750 2.8E-84 T 14-10-2018 Tharo_0862 9cfe842e8ed73002ad1e63d479a9362f 757 SMART SM01274 18 151 1.5E-76 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 Tharo_0862 9cfe842e8ed73002ad1e63d479a9362f 757 Gene3D G3DSA:3.40.50.720 161 444 8.6E-81 T 14-10-2018 Tharo_0862 9cfe842e8ed73002ad1e63d479a9362f 757 SUPERFAMILY SSF53223 10 161 2.16E-52 T 14-10-2018 Tharo_0862 9cfe842e8ed73002ad1e63d479a9362f 757 SMART SM00919 163 400 2.5E-135 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 Tharo_0862 9cfe842e8ed73002ad1e63d479a9362f 757 SUPERFAMILY SSF53659 429 753 3.08E-83 T 14-10-2018 Tharo_0862 9cfe842e8ed73002ad1e63d479a9362f 757 Pfam PF03949 Malic enzyme, NAD binding domain 165 358 1.3E-22 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 Tharo_0862 9cfe842e8ed73002ad1e63d479a9362f 757 Pfam PF01515 Phosphate acetyl/butaryl transferase 429 750 1.4E-86 T 14-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 Tharo_0862 9cfe842e8ed73002ad1e63d479a9362f 757 Pfam PF00390 Malic enzyme, N-terminal domain 19 151 9.6E-27 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 Tharo_0862 9cfe842e8ed73002ad1e63d479a9362f 757 SUPERFAMILY SSF51735 163 452 8.26E-85 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_0862 9cfe842e8ed73002ad1e63d479a9362f 757 Gene3D G3DSA:3.40.50.10380 2 160 1.4E-66 T 14-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 Tharo_0862 9cfe842e8ed73002ad1e63d479a9362f 757 PIRSF PIRSF036684 1 757 0.0 T 14-10-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 Tharo_1348 c25ea4ee7e0c8194d44f2d178c0b76c6 200 Gene3D G3DSA:1.10.10.10 86 183 1.2E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1348 c25ea4ee7e0c8194d44f2d178c0b76c6 200 Gene3D G3DSA:1.10.10.10 5 85 1.2E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1348 c25ea4ee7e0c8194d44f2d178c0b76c6 200 Pfam PF04079 Segregation and condensation complex subunit ScpB 12 172 1.3E-51 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 Tharo_1348 c25ea4ee7e0c8194d44f2d178c0b76c6 200 PIRSF PIRSF019345 2 199 5.1E-59 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 Tharo_1348 c25ea4ee7e0c8194d44f2d178c0b76c6 200 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 12 176 1.7E-34 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 Tharo_1348 c25ea4ee7e0c8194d44f2d178c0b76c6 200 SUPERFAMILY SSF46785 88 164 1.4E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1348 c25ea4ee7e0c8194d44f2d178c0b76c6 200 SUPERFAMILY SSF46785 9 85 1.36E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1170 e30b637b934cf5ed2a212bbb257bceb0 484 TIGRFAM TIGR00767 rho: transcription termination factor Rho 65 480 1.2E-209 T 14-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 Tharo_1170 e30b637b934cf5ed2a212bbb257bceb0 484 SMART SM00959 68 110 9.0E-17 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 Tharo_1170 e30b637b934cf5ed2a212bbb257bceb0 484 Hamap MF_01884 Transcription termination factor Rho [rho]. 64 482 236.461 T 14-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 Tharo_1170 e30b637b934cf5ed2a212bbb257bceb0 484 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 223 426 3.2E-24 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Tharo_1170 e30b637b934cf5ed2a212bbb257bceb0 484 SUPERFAMILY SSF68912 64 109 1.41E-10 T 14-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily Tharo_1170 e30b637b934cf5ed2a212bbb257bceb0 484 Gene3D G3DSA:1.10.720.10 64 110 7.8E-18 T 14-10-2018 Tharo_1170 e30b637b934cf5ed2a212bbb257bceb0 484 SMART SM00382 233 419 1.0E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1170 e30b637b934cf5ed2a212bbb257bceb0 484 Pfam PF07497 Rho termination factor, RNA-binding domain 115 188 8.2E-31 T 14-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 Tharo_1170 e30b637b934cf5ed2a212bbb257bceb0 484 Pfam PF07498 Rho termination factor, N-terminal domain 68 110 3.7E-15 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 Tharo_1170 e30b637b934cf5ed2a212bbb257bceb0 484 Gene3D G3DSA:3.40.50.300 193 480 4.9E-129 T 14-10-2018 Tharo_1170 e30b637b934cf5ed2a212bbb257bceb0 484 SMART SM00357 115 181 1.2E-15 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 Tharo_1170 e30b637b934cf5ed2a212bbb257bceb0 484 SUPERFAMILY SSF52540 153 434 1.46E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1170 e30b637b934cf5ed2a212bbb257bceb0 484 Gene3D G3DSA:2.40.50.140 111 186 3.3E-33 T 14-10-2018 Tharo_1170 e30b637b934cf5ed2a212bbb257bceb0 484 SUPERFAMILY SSF50249 112 188 1.24E-28 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_2729 d19a9427e0053f4ab7a75ac33a4f87bd 125 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 124 8.1E-71 T 14-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2729 d19a9427e0053f4ab7a75ac33a4f87bd 125 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2729 d19a9427e0053f4ab7a75ac33a4f87bd 125 PIRSF PIRSF002133 1 124 3.9E-55 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2729 d19a9427e0053f4ab7a75ac33a4f87bd 125 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.602 T 14-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2729 d19a9427e0053f4ab7a75ac33a4f87bd 125 Gene3D G3DSA:2.40.50.140 1 125 3.4E-64 T 14-10-2018 Tharo_2729 d19a9427e0053f4ab7a75ac33a4f87bd 125 Pfam PF00164 Ribosomal protein S12/S23 13 123 6.3E-43 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2729 d19a9427e0053f4ab7a75ac33a4f87bd 125 PRINTS PR01034 Ribosomal protein S12 signature 58 77 4.2E-61 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2729 d19a9427e0053f4ab7a75ac33a4f87bd 125 PRINTS PR01034 Ribosomal protein S12 signature 110 122 4.2E-61 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2729 d19a9427e0053f4ab7a75ac33a4f87bd 125 PRINTS PR01034 Ribosomal protein S12 signature 27 42 4.2E-61 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2729 d19a9427e0053f4ab7a75ac33a4f87bd 125 PRINTS PR01034 Ribosomal protein S12 signature 77 94 4.2E-61 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2729 d19a9427e0053f4ab7a75ac33a4f87bd 125 PRINTS PR01034 Ribosomal protein S12 signature 42 57 4.2E-61 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2729 d19a9427e0053f4ab7a75ac33a4f87bd 125 PRINTS PR01034 Ribosomal protein S12 signature 94 110 4.2E-61 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2729 d19a9427e0053f4ab7a75ac33a4f87bd 125 SUPERFAMILY SSF50249 2 124 5.4E-53 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_3217 ee394333213d866ca391e8e4c9f035bf 282 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 16 249 6.2E-94 T 14-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Tharo_3217 ee394333213d866ca391e8e4c9f035bf 282 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 17 228 5.9E-52 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Tharo_3217 ee394333213d866ca391e8e4c9f035bf 282 SUPERFAMILY SSF53790 11 260 1.7E-83 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Tharo_3217 ee394333213d866ca391e8e4c9f035bf 282 Gene3D G3DSA:3.40.1010.10 14 131 5.2E-46 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Tharo_3217 ee394333213d866ca391e8e4c9f035bf 282 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 96 129 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Tharo_3217 ee394333213d866ca391e8e4c9f035bf 282 Gene3D G3DSA:3.30.950.10 132 268 2.7E-50 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 Tharo_1735 ecc9741c95823b27c12f4242d03d8c12 148 Pfam PF01668 SmpB protein 3 145 1.1E-60 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 Tharo_1735 ecc9741c95823b27c12f4242d03d8c12 148 Gene3D G3DSA:2.40.280.10 1 124 1.3E-49 T 14-10-2018 IPR023620 Small protein B Tharo_1735 ecc9741c95823b27c12f4242d03d8c12 148 TIGRFAM TIGR00086 smpB: SsrA-binding protein 3 144 2.0E-56 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 Tharo_1735 ecc9741c95823b27c12f4242d03d8c12 148 Hamap MF_00023 SsrA-binding protein [smpB]. 1 148 74.604 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 Tharo_1735 ecc9741c95823b27c12f4242d03d8c12 148 SUPERFAMILY SSF74982 3 127 1.83E-51 T 14-10-2018 IPR023620 Small protein B Tharo_1735 ecc9741c95823b27c12f4242d03d8c12 148 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 3 121 9.0E-51 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 Tharo_1735 ecc9741c95823b27c12f4242d03d8c12 148 ProSitePatterns PS01317 SsrA-binding protein. 21 33 - T 14-10-2018 IPR020081 SsrA-binding protein, conserved site Tharo_0192 ce15c7405a68825f37d66d51f1b190af 316 Gene3D G3DSA:3.40.50.10680 9 276 9.9E-106 T 14-10-2018 Tharo_0192 ce15c7405a68825f37d66d51f1b190af 316 SUPERFAMILY SSF142338 5 308 4.58E-75 T 14-10-2018 Tharo_0192 ce15c7405a68825f37d66d51f1b190af 316 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 316 105.75 T 14-10-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 Tharo_0192 ce15c7405a68825f37d66d51f1b190af 316 Pfam PF01933 Uncharacterised protein family UPF0052 5 276 5.8E-41 T 14-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 Tharo_0192 ce15c7405a68825f37d66d51f1b190af 316 Gene3D G3DSA:1.10.8.240 39 126 9.9E-106 T 14-10-2018 Tharo_0192 ce15c7405a68825f37d66d51f1b190af 316 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 5 304 3.0E-84 T 14-10-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 Tharo_3310 39d69ddda8bf51233b5d1788751ecfda 222 SUPERFAMILY SSF52833 3 216 3.58E-42 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_3310 39d69ddda8bf51233b5d1788751ecfda 222 Gene3D G3DSA:3.40.30.10 2 214 6.6E-65 T 14-10-2018 Tharo_3310 39d69ddda8bf51233b5d1788751ecfda 222 Pfam PF01323 DSBA-like thioredoxin domain 5 206 1.7E-32 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 Tharo_2816 9bcc73ab654d29936185279a8fa70fd4 130 PIRSF PIRSF029543 1 130 4.8E-36 T 14-10-2018 IPR016924 Uncharacterised conserved protein UCP029543 Tharo_2882 aea2a596bc93f3c24f7c76f010d4f4d0 233 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 7 213 1.2E-59 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 Tharo_2882 aea2a596bc93f3c24f7c76f010d4f4d0 233 PIRSF PIRSF006293 4 232 4.6E-76 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 Tharo_2882 aea2a596bc93f3c24f7c76f010d4f4d0 233 Pfam PF06508 Queuosine biosynthesis protein QueC 6 219 4.6E-76 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 Tharo_2882 aea2a596bc93f3c24f7c76f010d4f4d0 233 SUPERFAMILY SSF52402 6 230 1.46E-62 T 14-10-2018 Tharo_2882 aea2a596bc93f3c24f7c76f010d4f4d0 233 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 5 226 55.054 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 Tharo_2882 aea2a596bc93f3c24f7c76f010d4f4d0 233 Gene3D G3DSA:3.40.50.620 5 228 1.0E-73 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_3035 68c14d3eb601d6fb7747a13ade5fa6ed 397 SUPERFAMILY SSF55073 230 382 3.3E-38 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_3035 68c14d3eb601d6fb7747a13ade5fa6ed 397 SMART SM00267 214 383 4.0E-44 T 14-10-2018 IPR000160 GGDEF domain Tharo_3035 68c14d3eb601d6fb7747a13ade5fa6ed 397 Pfam PF00990 Diguanylate cyclase, GGDEF domain 225 379 4.6E-36 T 14-10-2018 IPR000160 GGDEF domain Tharo_3035 68c14d3eb601d6fb7747a13ade5fa6ed 397 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 223 382 7.3E-39 T 14-10-2018 IPR000160 GGDEF domain Tharo_3035 68c14d3eb601d6fb7747a13ade5fa6ed 397 Gene3D G3DSA:3.30.70.270 214 383 6.3E-45 T 14-10-2018 Tharo_0089 753db72c89051aa3e66b88778226c954 209 SUPERFAMILY SSF47203 28 103 4.35E-24 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Tharo_0089 753db72c89051aa3e66b88778226c954 209 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 28 99 1.3E-15 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Tharo_0089 753db72c89051aa3e66b88778226c954 209 Gene3D G3DSA:1.20.140.10 10 108 6.5E-20 T 14-10-2018 Tharo_0089 753db72c89051aa3e66b88778226c954 209 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 58 77 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Tharo_3397 b13753bbd2b28fb8e5d1a4c50a489c1c 327 SUPERFAMILY SSF140931 240 280 1.83E-6 T 14-10-2018 IPR036597 Fido-like domain superfamily Tharo_3397 b13753bbd2b28fb8e5d1a4c50a489c1c 327 Pfam PF02661 Fic/DOC family 237 273 1.2E-8 T 14-10-2018 IPR003812 Fido domain Tharo_3397 b13753bbd2b28fb8e5d1a4c50a489c1c 327 Gene3D G3DSA:1.20.120.1870 192 319 1.6E-14 T 14-10-2018 Tharo_3397 b13753bbd2b28fb8e5d1a4c50a489c1c 327 Pfam PF13310 Virulence protein RhuM family 71 125 1.3E-19 T 14-10-2018 IPR011204 Virulence protein RhuM-like Tharo_1845 7e2d012189c3e8e9f91b4d9af4eff62f 143 Pfam PF13406 Transglycosylase SLT domain 2 61 1.0E-11 T 14-10-2018 IPR031304 Transglycosylase SLT domain 2 Tharo_1845 7e2d012189c3e8e9f91b4d9af4eff62f 143 Gene3D G3DSA:1.10.530.10 1 68 2.2E-12 T 14-10-2018 Tharo_1845 7e2d012189c3e8e9f91b4d9af4eff62f 143 SUPERFAMILY SSF47090 69 139 4.12E-18 T 14-10-2018 IPR036365 PGBD-like superfamily Tharo_1845 7e2d012189c3e8e9f91b4d9af4eff62f 143 SUPERFAMILY SSF53955 2 66 1.12E-13 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily Tharo_1845 7e2d012189c3e8e9f91b4d9af4eff62f 143 Pfam PF01471 Putative peptidoglycan binding domain 82 137 3.0E-11 T 14-10-2018 IPR002477 Peptidoglycan binding-like Tharo_1845 7e2d012189c3e8e9f91b4d9af4eff62f 143 Gene3D G3DSA:1.10.101.10 70 142 2.4E-11 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 Tharo_1605 ce2390726891ce3d3f6a99d7de593aed 411 SUPERFAMILY SSF53901 214 410 2.31E-66 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_1605 ce2390726891ce3d3f6a99d7de593aed 411 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 247 2.8E-63 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal Tharo_1605 ce2390726891ce3d3f6a99d7de593aed 411 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 368 5.4E-34 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal Tharo_1605 ce2390726891ce3d3f6a99d7de593aed 411 SUPERFAMILY SSF53901 4 252 1.04E-82 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_1605 ce2390726891ce3d3f6a99d7de593aed 411 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 409 1.3E-194 T 14-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 Tharo_1605 ce2390726891ce3d3f6a99d7de593aed 411 PIRSF PIRSF000447 1 411 7.1E-184 T 14-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 Tharo_1605 ce2390726891ce3d3f6a99d7de593aed 411 SMART SM00825 Beta-ketoacyl synthase 6 411 5.4E-17 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain Tharo_1605 ce2390726891ce3d3f6a99d7de593aed 411 Gene3D G3DSA:3.40.47.10 257 400 2.0E-47 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_1605 ce2390726891ce3d3f6a99d7de593aed 411 Gene3D G3DSA:3.40.47.10 1 255 3.3E-98 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_1605 ce2390726891ce3d3f6a99d7de593aed 411 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site Tharo_2927 b241c4295833f98221dd642ebd4d80f1 335 Pfam PF00107 Zinc-binding dehydrogenase 170 297 1.4E-32 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Tharo_2927 b241c4295833f98221dd642ebd4d80f1 335 Gene3D G3DSA:3.90.180.10 18 324 7.1E-97 T 14-10-2018 Tharo_2927 b241c4295833f98221dd642ebd4d80f1 335 Gene3D G3DSA:3.40.50.720 141 283 7.1E-97 T 14-10-2018 Tharo_2927 b241c4295833f98221dd642ebd4d80f1 335 SMART SM00829 10 333 3.4E-24 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Tharo_2927 b241c4295833f98221dd642ebd4d80f1 335 SUPERFAMILY SSF50129 1 164 1.67E-34 T 14-10-2018 IPR011032 GroES-like superfamily Tharo_2927 b241c4295833f98221dd642ebd4d80f1 335 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 89 2.4E-7 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Tharo_2927 b241c4295833f98221dd642ebd4d80f1 335 SUPERFAMILY SSF51735 136 309 1.28E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_0356 ed83d5686d376a1fea0cb17791c9d0e8 120 Pfam PF03646 FlaG protein 39 116 1.9E-16 T 14-10-2018 IPR005186 FlaG protein Tharo_0356 ed83d5686d376a1fea0cb17791c9d0e8 120 Gene3D G3DSA:3.30.160.170 25 116 1.6E-8 T 14-10-2018 IPR035924 FlaG-like superfamily Tharo_0356 ed83d5686d376a1fea0cb17791c9d0e8 120 SUPERFAMILY SSF160214 37 117 8.24E-20 T 14-10-2018 IPR035924 FlaG-like superfamily Tharo_2699 bf05da3ca82723b21e74640b37bd8789 326 SUPERFAMILY SSF56553 51 173 4.84E-39 T 14-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2699 bf05da3ca82723b21e74640b37bd8789 326 SUPERFAMILY SSF55257 5 229 1.37E-31 T 14-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2699 bf05da3ca82723b21e74640b37bd8789 326 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 27 224 9.5E-23 T 14-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2699 bf05da3ca82723b21e74640b37bd8789 326 SMART SM00662 21 230 1.4E-95 T 14-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2699 bf05da3ca82723b21e74640b37bd8789 326 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 252 322 7.0E-35 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2699 bf05da3ca82723b21e74640b37bd8789 326 Gene3D G3DSA:3.30.1360.10 16 222 9.7E-80 T 14-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2699 bf05da3ca82723b21e74640b37bd8789 326 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 3 313 35.485 T 14-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2699 bf05da3ca82723b21e74640b37bd8789 326 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 60 151 1.5E-23 T 14-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2699 bf05da3ca82723b21e74640b37bd8789 326 Gene3D G3DSA:1.10.150.20 241 324 5.2E-37 T 14-10-2018 Tharo_2699 bf05da3ca82723b21e74640b37bd8789 326 Gene3D G3DSA:2.170.120.12 51 173 9.7E-80 T 14-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2699 bf05da3ca82723b21e74640b37bd8789 326 SUPERFAMILY SSF47789 247 320 1.31E-26 T 14-10-2018 Tharo_2699 bf05da3ca82723b21e74640b37bd8789 326 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 22 312 1.2E-105 T 14-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2699 bf05da3ca82723b21e74640b37bd8789 326 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 244 304 9.9E-25 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_0523 9b3b50596a54800ca597ec97c13cde8b 478 SUPERFAMILY SSF46689 382 466 2.04E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_0523 9b3b50596a54800ca597ec97c13cde8b 478 SMART SM00382 162 309 2.7E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0523 9b3b50596a54800ca597ec97c13cde8b 478 Gene3D G3DSA:1.10.8.60 314 385 6.4E-21 T 14-10-2018 Tharo_0523 9b3b50596a54800ca597ec97c13cde8b 478 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 228 243 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Tharo_0523 9b3b50596a54800ca597ec97c13cde8b 478 SUPERFAMILY SSF52172 4 187 6.12E-41 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_0523 9b3b50596a54800ca597ec97c13cde8b 478 Gene3D G3DSA:3.40.50.2300 4 127 5.7E-34 T 14-10-2018 Tharo_0523 9b3b50596a54800ca597ec97c13cde8b 478 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 8 463 2.6E-209 T 14-10-2018 IPR010114 DNA-binding transcriptional regulator NtrC GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 Tharo_0523 9b3b50596a54800ca597ec97c13cde8b 478 SUPERFAMILY SSF52540 141 385 1.02E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0523 9b3b50596a54800ca597ec97c13cde8b 478 Gene3D G3DSA:1.10.10.60 386 466 1.0E-18 T 14-10-2018 Tharo_0523 9b3b50596a54800ca597ec97c13cde8b 478 Gene3D G3DSA:3.40.50.300 128 313 8.9E-66 T 14-10-2018 Tharo_0523 9b3b50596a54800ca597ec97c13cde8b 478 Pfam PF02954 Bacterial regulatory protein, Fis family 425 463 2.0E-12 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_0523 9b3b50596a54800ca597ec97c13cde8b 478 SMART SM00448 6 119 4.3E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_0523 9b3b50596a54800ca597ec97c13cde8b 478 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 355 364 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Tharo_0523 9b3b50596a54800ca597ec97c13cde8b 478 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Tharo_0523 9b3b50596a54800ca597ec97c13cde8b 478 Pfam PF00158 Sigma-54 interaction domain 142 308 6.0E-70 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Tharo_0523 9b3b50596a54800ca597ec97c13cde8b 478 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 429 446 1.5E-9 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_0523 9b3b50596a54800ca597ec97c13cde8b 478 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 446 466 1.5E-9 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_0523 9b3b50596a54800ca597ec97c13cde8b 478 Pfam PF00072 Response regulator receiver domain 8 119 7.4E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2979 1f4e5ec43a4372eec5658212d8ffec2e 206 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 80 3.4E-13 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 Tharo_2979 1f4e5ec43a4372eec5658212d8ffec2e 206 Gene3D G3DSA:3.40.30.10 2 205 3.8E-88 T 14-10-2018 Tharo_2979 1f4e5ec43a4372eec5658212d8ffec2e 206 Pfam PF00043 Glutathione S-transferase, C-terminal domain 130 196 1.3E-14 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal Tharo_2979 1f4e5ec43a4372eec5658212d8ffec2e 206 SUPERFAMILY SSF52833 1 87 2.84E-21 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_2979 1f4e5ec43a4372eec5658212d8ffec2e 206 Gene3D G3DSA:1.20.1050.10 87 195 3.8E-88 T 14-10-2018 Tharo_2979 1f4e5ec43a4372eec5658212d8ffec2e 206 SUPERFAMILY SSF47616 77 203 9.55E-41 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily Tharo_3198 d7c2faed6c3c2247e14e8d9429fe6b0c 199 Pfam PF07499 RuvA, C-terminal domain 153 197 3.2E-12 T 14-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 Tharo_3198 d7c2faed6c3c2247e14e8d9429fe6b0c 199 Gene3D G3DSA:1.10.150.20 67 138 3.0E-25 T 14-10-2018 Tharo_3198 d7c2faed6c3c2247e14e8d9429fe6b0c 199 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 197 30.646 T 14-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 Tharo_3198 d7c2faed6c3c2247e14e8d9429fe6b0c 199 Gene3D G3DSA:1.10.8.10 152 196 3.0E-5 T 14-10-2018 Tharo_3198 d7c2faed6c3c2247e14e8d9429fe6b0c 199 SUPERFAMILY SSF47781 66 135 4.13E-21 T 14-10-2018 IPR010994 RuvA domain 2-like Tharo_3198 d7c2faed6c3c2247e14e8d9429fe6b0c 199 SUPERFAMILY SSF46929 153 198 1.83E-8 T 14-10-2018 IPR036267 RuvA, C-terminal domain superfamily Tharo_3198 d7c2faed6c3c2247e14e8d9429fe6b0c 199 Gene3D G3DSA:2.40.50.140 1 66 9.1E-27 T 14-10-2018 Tharo_3198 d7c2faed6c3c2247e14e8d9429fe6b0c 199 SMART SM00278 73 92 5.7 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Tharo_3198 d7c2faed6c3c2247e14e8d9429fe6b0c 199 SMART SM00278 108 127 0.004 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Tharo_3198 d7c2faed6c3c2247e14e8d9429fe6b0c 199 Pfam PF01330 RuvA N terminal domain 1 62 4.4E-21 T 14-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 Tharo_3198 d7c2faed6c3c2247e14e8d9429fe6b0c 199 Pfam PF14520 Helix-hairpin-helix domain 72 130 1.5E-18 T 14-10-2018 Tharo_3198 d7c2faed6c3c2247e14e8d9429fe6b0c 199 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 196 3.4E-52 T 14-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 Tharo_3198 d7c2faed6c3c2247e14e8d9429fe6b0c 199 SUPERFAMILY SSF50249 1 63 8.0E-18 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_0897 f8bf1d70b37fbbda0136f62416cf53e7 265 Gene3D G3DSA:3.60.21.10 1 265 3.2E-73 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like Tharo_0897 f8bf1d70b37fbbda0136f62416cf53e7 265 SUPERFAMILY SSF56300 1 259 3.17E-52 T 14-10-2018 Tharo_0897 f8bf1d70b37fbbda0136f62416cf53e7 265 Pfam PF00149 Calcineurin-like phosphoesterase 4 126 1.8E-10 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Tharo_0897 f8bf1d70b37fbbda0136f62416cf53e7 265 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 1 262 4.2E-85 T 14-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 Tharo_0897 f8bf1d70b37fbbda0136f62416cf53e7 265 PIRSF PIRSF000903 1 265 3.6E-105 T 14-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 Tharo_0897 f8bf1d70b37fbbda0136f62416cf53e7 265 Hamap MF_00199 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [apaH]. 1 265 44.992 T 14-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 Tharo_1198 d3fcd44fcd6f326511f75f29bef6219e 164 Gene3D G3DSA:2.40.100.10 1 164 1.1E-69 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily Tharo_1198 d3fcd44fcd6f326511f75f29bef6219e 164 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 3 162 1.2E-47 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Tharo_1198 d3fcd44fcd6f326511f75f29bef6219e 164 SUPERFAMILY SSF50891 3 163 3.21E-58 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily Tharo_1198 d3fcd44fcd6f326511f75f29bef6219e 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 16 31 4.1E-11 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Tharo_1198 d3fcd44fcd6f326511f75f29bef6219e 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 119 134 4.1E-11 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Tharo_1198 d3fcd44fcd6f326511f75f29bef6219e 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 42 54 4.1E-11 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Tharo_1198 d3fcd44fcd6f326511f75f29bef6219e 164 PIRSF PIRSF001467 1 164 1.2E-27 T 14-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 Tharo_1198 d3fcd44fcd6f326511f75f29bef6219e 164 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 37 54 - T 14-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 Tharo_2069 7fbf7e0d59babffa976af1f037597a10 858 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 27 855 2.5E-236 T 14-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 Tharo_2069 7fbf7e0d59babffa976af1f037597a10 858 Pfam PF01966 HD domain 444 546 1.4E-7 T 14-10-2018 IPR006674 HD domain Tharo_2069 7fbf7e0d59babffa976af1f037597a10 858 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 858 304.882 T 14-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 Tharo_2069 7fbf7e0d59babffa976af1f037597a10 858 Gene3D G3DSA:3.30.70.260 786 858 1.5E-8 T 14-10-2018 Tharo_2069 7fbf7e0d59babffa976af1f037597a10 858 SUPERFAMILY SSF109604 410 534 5.34E-15 T 14-10-2018 Tharo_2069 7fbf7e0d59babffa976af1f037597a10 858 SUPERFAMILY SSF81593 187 302 5.81E-8 T 14-10-2018 Tharo_2069 7fbf7e0d59babffa976af1f037597a10 858 Pfam PF01842 ACT domain 789 849 1.2E-6 T 14-10-2018 IPR002912 ACT domain Tharo_2069 7fbf7e0d59babffa976af1f037597a10 858 Gene3D G3DSA:1.10.3210.10 425 572 4.1E-8 T 14-10-2018 Tharo_2069 7fbf7e0d59babffa976af1f037597a10 858 SUPERFAMILY SSF55021 786 841 1.53E-10 T 14-10-2018 Tharo_2069 7fbf7e0d59babffa976af1f037597a10 858 SUPERFAMILY SSF81301 13 163 3.54E-20 T 14-10-2018 Tharo_2069 7fbf7e0d59babffa976af1f037597a10 858 Pfam PF01909 Nucleotidyltransferase domain 61 97 1.5E-6 T 14-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Tharo_2069 7fbf7e0d59babffa976af1f037597a10 858 SMART SM00471 439 586 1.6E-4 T 14-10-2018 IPR003607 HD/PDEase domain Tharo_2069 7fbf7e0d59babffa976af1f037597a10 858 PIRSF PIRSF006288 3 858 0.0 T 14-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 Tharo_2069 7fbf7e0d59babffa976af1f037597a10 858 Pfam PF08335 GlnD PII-uridylyltransferase 169 307 5.2E-34 T 14-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 Tharo_2069 7fbf7e0d59babffa976af1f037597a10 858 SUPERFAMILY SSF55021 679 743 2.29E-7 T 14-10-2018 Tharo_2065 2f31c0d0b348d0f0b74e7fb9c50068a4 237 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 5 236 7.4E-101 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 Tharo_2065 2f31c0d0b348d0f0b74e7fb9c50068a4 237 Pfam PF00696 Amino acid kinase family 6 214 2.4E-29 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Tharo_2065 2f31c0d0b348d0f0b74e7fb9c50068a4 237 SUPERFAMILY SSF53633 4 236 9.82E-73 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Tharo_2065 2f31c0d0b348d0f0b74e7fb9c50068a4 237 Gene3D G3DSA:3.40.1160.10 2 237 4.6E-80 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Tharo_2065 2f31c0d0b348d0f0b74e7fb9c50068a4 237 PIRSF PIRSF005650 1 237 3.4E-92 T 14-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 Tharo_2065 2f31c0d0b348d0f0b74e7fb9c50068a4 237 Hamap MF_01220_B Uridylate kinase [pyrH]. 3 236 44.864 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 SUPERFAMILY SSF81923 4 141 4.32E-42 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 Gene3D G3DSA:1.10.8.60 767 859 1.6E-27 T 14-10-2018 Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 633 651 - T 14-10-2018 IPR028299 ClpA/B, conserved site 2 Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 677 695 1.2E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 710 724 1.2E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 603 621 1.2E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 666 1.2E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 69 3.8E-12 T 14-10-2018 IPR004176 Clp, N-terminal Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 145 4.1E-12 T 14-10-2018 IPR004176 Clp, N-terminal Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 Gene3D G3DSA:3.40.50.300 343 546 1.5E-68 T 14-10-2018 Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 Pfam PF07724 AAA domain (Cdc48 subfamily) 598 761 6.3E-55 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 767 847 9.1E-26 T 14-10-2018 IPR019489 Clp ATPase, C-terminal Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 SMART SM01086 767 856 4.8E-35 T 14-10-2018 IPR019489 Clp ATPase, C-terminal Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 335 8.9E-14 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 Gene3D G3DSA:3.40.50.300 148 342 2.9E-75 T 14-10-2018 Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 Gene3D G3DSA:3.40.50.300 552 765 3.8E-87 T 14-10-2018 Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 SMART SM00382 198 344 3.9E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 SMART SM00382 599 768 2.5E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 856 0.0 T 14-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 Gene3D G3DSA:1.10.1780.10 1 147 7.9E-33 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 SUPERFAMILY SSF52540 548 854 1.49E-83 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1717 1e316cda9206b8919bb577c0938f9d0a 860 SUPERFAMILY SSF52540 161 547 3.8E-100 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 SMART SM00387 1064 1186 3.2E-38 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 SMART SM00388 952 1017 6.4E-22 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 SUPERFAMILY SSF47226 1308 1442 6.28E-19 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 SMART SM00448 1210 1324 1.7E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 Gene3D G3DSA:3.30.565.10 1016 1188 7.0E-48 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 SMART SM00091 816 882 4.0E-11 T 14-10-2018 IPR000014 PAS domain Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 SMART SM00091 673 739 4.6E-11 T 14-10-2018 IPR000014 PAS domain Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 SMART SM00091 555 621 3.1E-9 T 14-10-2018 IPR000014 PAS domain Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 SMART SM01079 269 458 3.9E-41 T 14-10-2018 IPR006189 CHASE domain Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 Pfam PF13188 PAS domain 555 613 1.2E-8 T 14-10-2018 IPR000014 PAS domain Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 Pfam PF00512 His Kinase A (phospho-acceptor) domain 952 1017 3.1E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 672 790 2.5E-18 T 14-10-2018 IPR000014 PAS domain Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 815 934 3.7E-25 T 14-10-2018 IPR000014 PAS domain Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 553 674 3.0E-18 T 14-10-2018 IPR000014 PAS domain Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1111 1125 8.4E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1170 1183 8.4E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1129 1139 8.4E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1146 1164 8.4E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 Gene3D G3DSA:3.40.50.2300 1205 1340 3.7E-38 T 14-10-2018 Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 Gene3D G3DSA:3.30.450.20 541 665 9.4E-17 T 14-10-2018 Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 Gene3D G3DSA:3.30.450.20 666 781 7.8E-23 T 14-10-2018 Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 SUPERFAMILY SSF52172 1209 1334 3.27E-37 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 Gene3D G3DSA:1.10.287.130 931 1015 6.7E-25 T 14-10-2018 Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 SMART SM00086 628 668 5.2 T 14-10-2018 IPR001610 PAC motif Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 SMART SM00086 746 783 0.034 T 14-10-2018 IPR001610 PAC motif Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 SMART SM00086 892 932 23.0 T 14-10-2018 IPR001610 PAC motif Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1067 1185 9.4E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 SUPERFAMILY SSF55785 543 666 3.53E-18 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 SUPERFAMILY SSF55874 1006 1185 8.91E-47 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 Gene3D G3DSA:3.30.450.350 273 484 1.7E-29 T 14-10-2018 Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 Pfam PF00989 PAS fold 816 929 3.1E-12 T 14-10-2018 IPR013767 PAS fold GO:0006355 Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 SUPERFAMILY SSF55785 801 929 1.13E-25 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 Pfam PF05231 MASE1 29 229 1.7E-21 T 14-10-2018 IPR007895 MASE1 Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 SMART SM00073 1356 1455 0.0064 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 Pfam PF03924 CHASE domain 272 453 7.4E-39 T 14-10-2018 IPR006189 CHASE domain Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 Pfam PF08447 PAS fold 697 767 2.6E-16 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 Pfam PF01627 Hpt domain 1367 1435 8.3E-7 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 Gene3D G3DSA:1.20.120.160 1343 1454 1.6E-15 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 SUPERFAMILY SSF55785 679 786 1.31E-23 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 SUPERFAMILY SSF47384 935 1018 9.81E-20 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 Pfam PF00072 Response regulator receiver domain 1212 1323 2.5E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1391 9fbc741c85262d573d2fd30ab6738b61 1461 Gene3D G3DSA:3.30.450.20 812 930 2.4E-32 T 14-10-2018 Tharo_0934 7373b452456a407e363527c977ea51e4 490 Pfam PF00483 Nucleotidyl transferase 8 299 1.5E-61 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Tharo_0934 7373b452456a407e363527c977ea51e4 490 Pfam PF01050 Mannose-6-phosphate isomerase 328 478 8.7E-73 T 14-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 Tharo_0934 7373b452456a407e363527c977ea51e4 490 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 6 482 7.6E-208 T 14-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 Tharo_0934 7373b452456a407e363527c977ea51e4 490 SUPERFAMILY SSF53448 7 293 2.93E-64 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_0934 7373b452456a407e363527c977ea51e4 490 SUPERFAMILY SSF51182 191 484 5.62E-88 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily Tharo_0934 7373b452456a407e363527c977ea51e4 490 Gene3D G3DSA:2.60.120.10 368 467 2.6E-18 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Tharo_0934 7373b452456a407e363527c977ea51e4 490 Gene3D G3DSA:3.90.550.10 5 363 8.4E-111 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_1557 d9a511e2d5096a0256b738b77f050e1c 950 SUPERFAMILY SSF51621 40 950 0.0 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Tharo_1557 d9a511e2d5096a0256b738b77f050e1c 950 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 32 950 19.581 T 14-10-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Tharo_1557 d9a511e2d5096a0256b738b77f050e1c 950 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 599 611 - T 14-10-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Tharo_1557 d9a511e2d5096a0256b738b77f050e1c 950 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 283 298 1.7E-56 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Tharo_1557 d9a511e2d5096a0256b738b77f050e1c 950 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 639 668 1.7E-56 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Tharo_1557 d9a511e2d5096a0256b738b77f050e1c 950 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 434 454 1.7E-56 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Tharo_1557 d9a511e2d5096a0256b738b77f050e1c 950 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 170 183 1.7E-56 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Tharo_1557 d9a511e2d5096a0256b738b77f050e1c 950 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 223 239 1.7E-56 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Tharo_1557 d9a511e2d5096a0256b738b77f050e1c 950 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 597 617 1.7E-56 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Tharo_1557 d9a511e2d5096a0256b738b77f050e1c 950 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 773 799 1.7E-56 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Tharo_1557 d9a511e2d5096a0256b738b77f050e1c 950 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 171 182 - T 14-10-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Tharo_1557 d9a511e2d5096a0256b738b77f050e1c 950 Gene3D G3DSA:1.20.1440.90 324 437 3.5E-10 T 14-10-2018 Tharo_1557 d9a511e2d5096a0256b738b77f050e1c 950 Pfam PF00311 Phosphoenolpyruvate carboxylase 167 950 8.2E-288 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Tharo_2318 6ded265639dd1d30231c7741db173da0 62 Gene3D G3DSA:2.40.50.140 1 61 3.4E-29 T 14-10-2018 Tharo_2318 6ded265639dd1d30231c7741db173da0 62 ProSitePatterns PS00352 'Cold-shock' domain signature. 10 29 - T 14-10-2018 IPR019844 Cold-shock conserved site Tharo_2318 6ded265639dd1d30231c7741db173da0 62 SMART SM00357 1 62 1.9E-27 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 Tharo_2318 6ded265639dd1d30231c7741db173da0 62 Pfam PF00313 'Cold-shock' DNA-binding domain 1 61 8.7E-30 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Tharo_2318 6ded265639dd1d30231c7741db173da0 62 PIRSF PIRSF002599 1 62 2.0E-22 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 Tharo_2318 6ded265639dd1d30231c7741db173da0 62 SUPERFAMILY SSF50249 1 60 1.05E-23 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_2318 6ded265639dd1d30231c7741db173da0 62 PRINTS PR00050 Cold shock protein signature 20 29 1.5E-8 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Tharo_2318 6ded265639dd1d30231c7741db173da0 62 PRINTS PR00050 Cold shock protein signature 35 53 1.5E-8 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Tharo_0212 fbc9a0bce631eca7377c76c4a22aac55 142 Pfam PF01850 PIN domain 3 128 5.7E-13 T 14-10-2018 IPR002716 PIN domain Tharo_0212 fbc9a0bce631eca7377c76c4a22aac55 142 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 137 10.271 T 14-10-2018 IPR022907 VapC family GO:0004540 Tharo_0212 fbc9a0bce631eca7377c76c4a22aac55 142 SUPERFAMILY SSF88723 1 134 1.54E-18 T 14-10-2018 IPR029060 PIN-like domain superfamily Tharo_0212 fbc9a0bce631eca7377c76c4a22aac55 142 Gene3D G3DSA:3.40.50.1010 1 129 7.7E-16 T 14-10-2018 Tharo_3334 8a88c6775320cf3ffe26b51c0e4ba45d 616 Pfam PF01343 Peptidase family S49 388 538 1.5E-45 T 14-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 Tharo_3334 8a88c6775320cf3ffe26b51c0e4ba45d 616 Pfam PF01343 Peptidase family S49 133 290 1.1E-25 T 14-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 Tharo_3334 8a88c6775320cf3ffe26b51c0e4ba45d 616 SUPERFAMILY SSF52096 318 524 3.21E-40 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_3334 8a88c6775320cf3ffe26b51c0e4ba45d 616 TIGRFAM TIGR00705 SppA_67K: signal peptide peptidase SppA, 67K type 84 609 2.4E-149 T 14-10-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 Tharo_3334 8a88c6775320cf3ffe26b51c0e4ba45d 616 Gene3D G3DSA:3.90.226.10 89 310 5.0E-156 T 14-10-2018 Tharo_3334 8a88c6775320cf3ffe26b51c0e4ba45d 616 Gene3D G3DSA:3.40.1750.10 181 494 5.0E-156 T 14-10-2018 Tharo_3334 8a88c6775320cf3ffe26b51c0e4ba45d 616 SUPERFAMILY SSF52096 38 280 9.59E-19 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_3334 8a88c6775320cf3ffe26b51c0e4ba45d 616 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 323 534 2.5E-48 T 14-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 Tharo_3334 8a88c6775320cf3ffe26b51c0e4ba45d 616 Gene3D G3DSA:3.90.226.10 314 536 5.0E-156 T 14-10-2018 Tharo_3334 8a88c6775320cf3ffe26b51c0e4ba45d 616 PIRSF PIRSF001217 3 616 1.8E-186 T 14-10-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 Tharo_1831 6490a3c50d8093e8cc5db4fa306fc00b 384 Gene3D G3DSA:3.40.50.1970 1 183 1.9E-54 T 14-10-2018 Tharo_1831 6490a3c50d8093e8cc5db4fa306fc00b 384 Gene3D G3DSA:1.20.1090.10 184 383 6.4E-64 T 14-10-2018 Tharo_1831 6490a3c50d8093e8cc5db4fa306fc00b 384 SUPERFAMILY SSF56796 3 382 1.57E-118 T 14-10-2018 Tharo_1831 6490a3c50d8093e8cc5db4fa306fc00b 384 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 376 2.0E-116 T 14-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 Tharo_1831 6490a3c50d8093e8cc5db4fa306fc00b 384 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 172 200 - T 14-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 Tharo_1058 c5bfd584c2700fbbf6fb5ad7f209a99e 599 SUPERFAMILY SSF55261 292 420 1.42E-41 T 14-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 Tharo_1058 c5bfd584c2700fbbf6fb5ad7f209a99e 599 Gene3D G3DSA:3.30.1360.30 273 422 2.5E-197 T 14-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 Tharo_1058 c5bfd584c2700fbbf6fb5ad7f209a99e 599 Pfam PF02938 GAD domain 309 408 7.5E-29 T 14-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 Tharo_1058 c5bfd584c2700fbbf6fb5ad7f209a99e 599 PRINTS PR01042 Aspartyl-tRNA synthetase signature 477 493 1.6E-26 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_1058 c5bfd584c2700fbbf6fb5ad7f209a99e 599 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 221 1.6E-26 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_1058 c5bfd584c2700fbbf6fb5ad7f209a99e 599 PRINTS PR01042 Aspartyl-tRNA synthetase signature 191 203 1.6E-26 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_1058 c5bfd584c2700fbbf6fb5ad7f209a99e 599 PRINTS PR01042 Aspartyl-tRNA synthetase signature 521 535 1.6E-26 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_1058 c5bfd584c2700fbbf6fb5ad7f209a99e 599 SUPERFAMILY SSF50249 1 105 6.67E-34 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_1058 c5bfd584c2700fbbf6fb5ad7f209a99e 599 Gene3D G3DSA:2.40.50.140 1 106 2.7E-35 T 14-10-2018 Tharo_1058 c5bfd584c2700fbbf6fb5ad7f209a99e 599 SUPERFAMILY SSF55681 110 588 5.39E-109 T 14-10-2018 Tharo_1058 c5bfd584c2700fbbf6fb5ad7f209a99e 599 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 586 9.0E-253 T 14-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 Tharo_1058 c5bfd584c2700fbbf6fb5ad7f209a99e 599 Pfam PF00152 tRNA synthetases class II (D, K and N) 119 561 3.3E-109 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_1058 c5bfd584c2700fbbf6fb5ad7f209a99e 599 Pfam PF01336 OB-fold nucleic acid binding domain 18 102 1.1E-19 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 Tharo_1058 c5bfd584c2700fbbf6fb5ad7f209a99e 599 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 1 587 33.995 T 14-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 Tharo_1058 c5bfd584c2700fbbf6fb5ad7f209a99e 599 Gene3D G3DSA:3.30.930.10 118 585 2.5E-197 T 14-10-2018 Tharo_0926 a64cdc2612bf287b146c035e071b41e5 304 Gene3D G3DSA:3.30.1490.20 115 179 5.1E-22 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Tharo_0926 a64cdc2612bf287b146c035e071b41e5 304 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 6 302 33.202 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Tharo_0926 a64cdc2612bf287b146c035e071b41e5 304 Pfam PF01820 D-ala D-ala ligase N-terminus 7 89 1.7E-18 T 14-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Tharo_0926 a64cdc2612bf287b146c035e071b41e5 304 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 66 77 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Tharo_0926 a64cdc2612bf287b146c035e071b41e5 304 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 7 301 6.4E-96 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Tharo_0926 a64cdc2612bf287b146c035e071b41e5 304 Gene3D G3DSA:3.40.50.20 1 87 4.4E-32 T 14-10-2018 Tharo_0926 a64cdc2612bf287b146c035e071b41e5 304 Pfam PF07478 D-ala D-ala ligase C-terminus 108 298 3.4E-50 T 14-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Tharo_0926 a64cdc2612bf287b146c035e071b41e5 304 SUPERFAMILY SSF52440 7 99 1.73E-30 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Tharo_0926 a64cdc2612bf287b146c035e071b41e5 304 PIRSF PIRSF039102 43 303 4.2E-76 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Tharo_0926 a64cdc2612bf287b146c035e071b41e5 304 PIRSF PIRSF039102 4 51 3.6E-8 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Tharo_0926 a64cdc2612bf287b146c035e071b41e5 304 SUPERFAMILY SSF56059 100 300 4.04E-55 T 14-10-2018 Tharo_0926 a64cdc2612bf287b146c035e071b41e5 304 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 244 272 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Tharo_3449 87f11ebecf12f6eb9b4b9e1144652dbb 691 Gene3D G3DSA:2.70.20.10 219 495 1.4E-159 T 14-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 Tharo_3449 87f11ebecf12f6eb9b4b9e1144652dbb 691 SMART SM00493 1 130 2.9E-24 T 14-10-2018 IPR006171 TOPRIM domain Tharo_3449 87f11ebecf12f6eb9b4b9e1144652dbb 691 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 665 1.4E-204 T 14-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 Tharo_3449 87f11ebecf12f6eb9b4b9e1144652dbb 691 SUPERFAMILY SSF56712 1 612 8.11E-173 T 14-10-2018 IPR023405 DNA topoisomerase, type IA, core domain Tharo_3449 87f11ebecf12f6eb9b4b9e1144652dbb 691 SMART SM00436 130 225 1.4E-21 T 14-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 Tharo_3449 87f11ebecf12f6eb9b4b9e1144652dbb 691 Gene3D G3DSA:1.10.290.10 289 418 1.4E-159 T 14-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 Tharo_3449 87f11ebecf12f6eb9b4b9e1144652dbb 691 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 634 670 1.1E-6 T 14-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 Tharo_3449 87f11ebecf12f6eb9b4b9e1144652dbb 691 Pfam PF01751 Toprim domain 3 137 3.0E-17 T 14-10-2018 IPR006171 TOPRIM domain Tharo_3449 87f11ebecf12f6eb9b4b9e1144652dbb 691 Pfam PF01131 DNA topoisomerase 157 599 1.9E-112 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Tharo_3449 87f11ebecf12f6eb9b4b9e1144652dbb 691 SMART SM00437 280 565 8.3E-73 T 14-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 Tharo_3449 87f11ebecf12f6eb9b4b9e1144652dbb 691 Gene3D G3DSA:1.10.460.10 164 609 1.4E-159 T 14-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 Tharo_3449 87f11ebecf12f6eb9b4b9e1144652dbb 691 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 317 332 - T 14-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 Tharo_3449 87f11ebecf12f6eb9b4b9e1144652dbb 691 Gene3D G3DSA:3.40.50.140 1 158 1.5E-53 T 14-10-2018 Tharo_3449 87f11ebecf12f6eb9b4b9e1144652dbb 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 195 213 7.6E-24 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Tharo_3449 87f11ebecf12f6eb9b4b9e1144652dbb 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 323 332 7.6E-24 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Tharo_3449 87f11ebecf12f6eb9b4b9e1144652dbb 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 404 420 7.6E-24 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Tharo_3449 87f11ebecf12f6eb9b4b9e1144652dbb 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 104 117 7.6E-24 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Tharo_3449 87f11ebecf12f6eb9b4b9e1144652dbb 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 528 542 7.6E-24 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Tharo_0134 598fb0938604df0b642d638657e73a97 491 ProSitePatterns PS00571 Amidases signature. 149 180 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 Tharo_0134 598fb0938604df0b642d638657e73a97 491 Gene3D G3DSA:3.90.1300.10 1 490 8.9E-202 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Tharo_0134 598fb0938604df0b642d638657e73a97 491 SUPERFAMILY SSF75304 2 487 6.02E-163 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Tharo_0134 598fb0938604df0b642d638657e73a97 491 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 10 481 4.4E-176 T 14-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Tharo_0134 598fb0938604df0b642d638657e73a97 491 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 9 481 93.261 T 14-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Tharo_0134 598fb0938604df0b642d638657e73a97 491 Pfam PF01425 Amidase 23 470 4.3E-155 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Tharo_2984 f4b3c3565ca01d308b65ef03864b580c 310 Pfam PF01171 PP-loop family 52 212 2.4E-13 T 14-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 Tharo_2984 f4b3c3565ca01d308b65ef03864b580c 310 Gene3D G3DSA:3.40.50.620 21 277 2.1E-43 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_2984 f4b3c3565ca01d308b65ef03864b580c 310 Hamap MF_01850 tRNA-cytidine(32) 2-sulfurtransferase [ttcA]. 20 279 55.552 T 14-10-2018 IPR012089 tRNA-cytidine(32) 2-sulfurtransferase GO:0008033 Tharo_2984 f4b3c3565ca01d308b65ef03864b580c 310 PIRSF PIRSF004976 13 284 6.0E-66 T 14-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 Tharo_2984 f4b3c3565ca01d308b65ef03864b580c 310 SUPERFAMILY SSF52402 30 246 1.12E-51 T 14-10-2018 Tharo_1543 fa1f55294e02b8d2a742316bdc6c7bbf 541 SMART SM00387 433 540 1.8E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1543 fa1f55294e02b8d2a742316bdc6c7bbf 541 SMART SM00388 327 392 5.3E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1543 fa1f55294e02b8d2a742316bdc6c7bbf 541 PRINTS PR00344 Bacterial sensor protein C-terminal signature 501 519 1.1E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1543 fa1f55294e02b8d2a742316bdc6c7bbf 541 PRINTS PR00344 Bacterial sensor protein C-terminal signature 490 500 1.1E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1543 fa1f55294e02b8d2a742316bdc6c7bbf 541 PRINTS PR00344 Bacterial sensor protein C-terminal signature 472 486 1.1E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1543 fa1f55294e02b8d2a742316bdc6c7bbf 541 SUPERFAMILY SSF47384 321 390 6.87E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_1543 fa1f55294e02b8d2a742316bdc6c7bbf 541 Gene3D G3DSA:1.10.287.130 314 391 4.6E-16 T 14-10-2018 Tharo_1543 fa1f55294e02b8d2a742316bdc6c7bbf 541 SUPERFAMILY SSF55874 383 534 2.23E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1543 fa1f55294e02b8d2a742316bdc6c7bbf 541 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 434 534 1.6E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1543 fa1f55294e02b8d2a742316bdc6c7bbf 541 Gene3D G3DSA:3.30.450.20 182 264 8.3E-7 T 14-10-2018 Tharo_1543 fa1f55294e02b8d2a742316bdc6c7bbf 541 Pfam PF13188 PAS domain 198 230 1.5E-7 T 14-10-2018 IPR000014 PAS domain Tharo_1543 fa1f55294e02b8d2a742316bdc6c7bbf 541 SUPERFAMILY SSF55785 187 233 3.14E-7 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_1543 fa1f55294e02b8d2a742316bdc6c7bbf 541 Gene3D G3DSA:3.30.565.10 395 540 6.2E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1543 fa1f55294e02b8d2a742316bdc6c7bbf 541 Pfam PF00512 His Kinase A (phospho-acceptor) domain 327 391 1.3E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1543 fa1f55294e02b8d2a742316bdc6c7bbf 541 SMART SM00091 194 263 0.0045 T 14-10-2018 IPR000014 PAS domain Tharo_2487 37974b7fc273ea0c481aabf24bb6835c 360 Pfam PF02661 Fic/DOC family 146 213 3.4E-16 T 14-10-2018 IPR003812 Fido domain Tharo_2487 37974b7fc273ea0c481aabf24bb6835c 360 Gene3D G3DSA:1.10.3290.10 41 278 1.0E-36 T 14-10-2018 IPR036597 Fido-like domain superfamily Tharo_2487 37974b7fc273ea0c481aabf24bb6835c 360 PIRSF PIRSF038925 1 359 5.7E-112 T 14-10-2018 IPR026287 Adenosine monophosphate-protein transferase Tharo_2487 37974b7fc273ea0c481aabf24bb6835c 360 SUPERFAMILY SSF140931 94 281 4.05E-31 T 14-10-2018 IPR036597 Fido-like domain superfamily Tharo_2487 37974b7fc273ea0c481aabf24bb6835c 360 Pfam PF13784 Fic/DOC family N-terminal 27 108 1.6E-23 T 14-10-2018 IPR025758 Fic/DOC N-terminal Tharo_1788 9df0fee4269c6649d92d746cc9b6e1fb 262 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 9 106 3.2E-11 T 14-10-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 Tharo_1788 9df0fee4269c6649d92d746cc9b6e1fb 262 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 153 247 1.4E-27 T 14-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 Tharo_1788 9df0fee4269c6649d92d746cc9b6e1fb 262 SUPERFAMILY SSF63848 151 250 6.54E-28 T 14-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 Tharo_1788 9df0fee4269c6649d92d746cc9b6e1fb 262 Gene3D G3DSA:3.30.750.120 4 120 1.6E-15 T 14-10-2018 IPR038061 MinC, Proteobacteria, N-terminal domain superfamily Tharo_1788 9df0fee4269c6649d92d746cc9b6e1fb 262 Gene3D G3DSA:2.160.20.70 149 261 3.3E-29 T 14-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 Tharo_1788 9df0fee4269c6649d92d746cc9b6e1fb 262 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 9 260 24.289 T 14-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 Tharo_1788 9df0fee4269c6649d92d746cc9b6e1fb 262 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 11 259 7.4E-49 T 14-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 Tharo_0921 5915791444237094387ebdb3940e2a1a 362 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 360 23.832 T 14-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_0921 5915791444237094387ebdb3940e2a1a 362 ProSitePatterns PS01348 MraY family signature 2. 190 201 - T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_0921 5915791444237094387ebdb3940e2a1a 362 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 68 80 3.3E-5 T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_0921 5915791444237094387ebdb3940e2a1a 362 Pfam PF00953 Glycosyl transferase family 4 99 285 8.8E-33 T 14-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 Tharo_0921 5915791444237094387ebdb3940e2a1a 362 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 37 362 4.9E-129 T 14-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_0921 5915791444237094387ebdb3940e2a1a 362 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_2545 8ea1d1f2d4251db7a3102c3ef7ca75d4 377 Gene3D G3DSA:1.20.140.10 233 377 7.5E-47 T 14-10-2018 Tharo_2545 8ea1d1f2d4251db7a3102c3ef7ca75d4 377 SUPERFAMILY SSF56645 1 224 9.03E-72 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Tharo_2545 8ea1d1f2d4251db7a3102c3ef7ca75d4 377 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 1.5E-24 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Tharo_2545 8ea1d1f2d4251db7a3102c3ef7ca75d4 377 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 214 2.0E-26 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Tharo_2545 8ea1d1f2d4251db7a3102c3ef7ca75d4 377 PIRSF PIRSF016578 131 358 1.4E-19 T 14-10-2018 Tharo_2545 8ea1d1f2d4251db7a3102c3ef7ca75d4 377 PIRSF PIRSF016578 5 101 4.1E-7 T 14-10-2018 Tharo_2545 8ea1d1f2d4251db7a3102c3ef7ca75d4 377 SUPERFAMILY SSF47203 225 375 3.38E-49 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Tharo_2545 8ea1d1f2d4251db7a3102c3ef7ca75d4 377 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Tharo_2545 8ea1d1f2d4251db7a3102c3ef7ca75d4 377 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 375 2.7E-42 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Tharo_2545 8ea1d1f2d4251db7a3102c3ef7ca75d4 377 Gene3D G3DSA:1.10.540.10 1 120 1.7E-33 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Tharo_2545 8ea1d1f2d4251db7a3102c3ef7ca75d4 377 Gene3D G3DSA:2.40.110.10 121 232 2.2E-36 T 14-10-2018 Tharo_1189 feae00373d530eb6e82d78acc3fc96f0 401 Gene3D G3DSA:3.40.50.1100 60 390 1.1E-184 T 14-10-2018 Tharo_1189 feae00373d530eb6e82d78acc3fc96f0 401 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 13 396 5.9E-191 T 14-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Tharo_1189 feae00373d530eb6e82d78acc3fc96f0 401 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 87 101 - T 14-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Tharo_1189 feae00373d530eb6e82d78acc3fc96f0 401 PIRSF PIRSF001413 1 401 2.4E-162 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Tharo_1189 feae00373d530eb6e82d78acc3fc96f0 401 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 8 397 52.32 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Tharo_1189 feae00373d530eb6e82d78acc3fc96f0 401 Gene3D G3DSA:3.40.50.1100 16 212 1.1E-184 T 14-10-2018 Tharo_1189 feae00373d530eb6e82d78acc3fc96f0 401 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 59 383 9.3E-50 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Tharo_1189 feae00373d530eb6e82d78acc3fc96f0 401 SUPERFAMILY SSF53686 9 395 6.55E-151 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Tharo_2573 b8d4d88bc5d4ec139f5d9a374916d399 294 Pfam PF00483 Nucleotidyl transferase 5 241 1.5E-69 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Tharo_2573 b8d4d88bc5d4ec139f5d9a374916d399 294 SUPERFAMILY SSF53448 4 290 1.13E-93 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_2573 b8d4d88bc5d4ec139f5d9a374916d399 294 Gene3D G3DSA:3.90.550.10 1 294 1.2E-86 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_2573 b8d4d88bc5d4ec139f5d9a374916d399 294 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 5 290 1.3E-156 T 14-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 Tharo_2333 421daff5471ad951228e33ce9316a6b8 345 SUPERFAMILY SSF55347 149 313 7.46E-53 T 14-10-2018 Tharo_2333 421daff5471ad951228e33ce9316a6b8 345 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 345 2.4E-129 T 14-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Tharo_2333 421daff5471ad951228e33ce9316a6b8 345 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 144 160 - T 14-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Tharo_2333 421daff5471ad951228e33ce9316a6b8 345 SMART SM00859 3 141 2.5E-59 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Tharo_2333 421daff5471ad951228e33ce9316a6b8 345 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 160 316 3.7E-16 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Tharo_2333 421daff5471ad951228e33ce9316a6b8 345 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 339 43.462 T 14-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Tharo_2333 421daff5471ad951228e33ce9316a6b8 345 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 140 4.9E-37 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Tharo_2333 421daff5471ad951228e33ce9316a6b8 345 Gene3D G3DSA:3.30.360.10 147 313 2.4E-129 T 14-10-2018 Tharo_2333 421daff5471ad951228e33ce9316a6b8 345 Gene3D G3DSA:3.40.50.720 3 331 2.4E-129 T 14-10-2018 Tharo_2333 421daff5471ad951228e33ce9316a6b8 345 SUPERFAMILY SSF51735 2 172 1.02E-54 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_0713 d7153bf33e9526d8a655526f87d0995e 573 Gene3D G3DSA:3.40.50.300 7 230 6.3E-35 T 14-10-2018 Tharo_0713 d7153bf33e9526d8a655526f87d0995e 573 Pfam PF13361 UvrD-like helicase C-terminal domain 476 559 4.2E-6 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Tharo_0713 d7153bf33e9526d8a655526f87d0995e 573 Gene3D G3DSA:3.40.50.300 445 572 2.7E-8 T 14-10-2018 Tharo_0713 d7153bf33e9526d8a655526f87d0995e 573 SUPERFAMILY SSF52540 10 568 1.17E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0713 d7153bf33e9526d8a655526f87d0995e 573 Pfam PF00580 UvrD/REP helicase N-terminal domain 134 226 2.5E-17 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 Tharo_0030 0e888e8147ddc8b94857336aa05a1f9d 1110 Pfam PF12794 Mechanosensitive ion channel inner membrane domain 1 495 817 1.2E-95 T 14-10-2018 IPR025692 Mechanosensitive ion channel inner membrane domain 1 Tharo_0030 0e888e8147ddc8b94857336aa05a1f9d 1110 SUPERFAMILY SSF50182 919 984 2.94E-17 T 14-10-2018 IPR010920 LSM domain superfamily Tharo_0030 0e888e8147ddc8b94857336aa05a1f9d 1110 SUPERFAMILY SSF82861 833 917 8.63E-6 T 14-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 Tharo_0030 0e888e8147ddc8b94857336aa05a1f9d 1110 Pfam PF12795 Mechanosensitive ion channel porin domain 36 262 4.9E-46 T 14-10-2018 IPR024393 Mechanosensitive ion channel MscS, porin domain Tharo_0030 0e888e8147ddc8b94857336aa05a1f9d 1110 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 948 982 - T 14-10-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 Tharo_0030 0e888e8147ddc8b94857336aa05a1f9d 1110 SUPERFAMILY SSF82689 987 1085 5.49E-26 T 14-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 Tharo_0030 0e888e8147ddc8b94857336aa05a1f9d 1110 Pfam PF00924 Mechanosensitive ion channel 876 1075 7.6E-56 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 Tharo_0030 0e888e8147ddc8b94857336aa05a1f9d 1110 Gene3D G3DSA:3.30.70.100 987 1080 5.4E-20 T 14-10-2018 Tharo_0030 0e888e8147ddc8b94857336aa05a1f9d 1110 Gene3D G3DSA:2.30.30.60 934 983 1.1E-14 T 14-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily Tharo_2948 ca9157e1b012d0a4ec26b7c53e0e35dc 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 226 5.1E-25 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Tharo_2948 ca9157e1b012d0a4ec26b7c53e0e35dc 397 PIRSF PIRSF016578 13 113 0.014 T 14-10-2018 Tharo_2948 ca9157e1b012d0a4ec26b7c53e0e35dc 397 PIRSF PIRSF016578 131 397 1.8E-8 T 14-10-2018 Tharo_2948 ca9157e1b012d0a4ec26b7c53e0e35dc 397 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 351 370 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Tharo_2948 ca9157e1b012d0a4ec26b7c53e0e35dc 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 241 392 2.5E-38 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Tharo_2948 ca9157e1b012d0a4ec26b7c53e0e35dc 397 SUPERFAMILY SSF47203 240 394 1.18E-41 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Tharo_2948 ca9157e1b012d0a4ec26b7c53e0e35dc 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 123 1.1E-33 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Tharo_2948 ca9157e1b012d0a4ec26b7c53e0e35dc 397 Gene3D G3DSA:1.10.540.10 2 125 5.1E-44 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Tharo_2948 ca9157e1b012d0a4ec26b7c53e0e35dc 397 Gene3D G3DSA:2.40.110.10 126 246 6.8E-41 T 14-10-2018 Tharo_2948 ca9157e1b012d0a4ec26b7c53e0e35dc 397 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 129 141 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Tharo_2948 ca9157e1b012d0a4ec26b7c53e0e35dc 397 SUPERFAMILY SSF56645 5 254 5.1E-79 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Tharo_2948 ca9157e1b012d0a4ec26b7c53e0e35dc 397 Gene3D G3DSA:1.20.140.10 247 397 7.5E-43 T 14-10-2018 Tharo_3387 6e1403c0bfbe16149fa8f7385e0fdaea 485 Pfam PF02386 Cation transport protein 42 477 4.5E-62 T 14-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 Tharo_3387 6e1403c0bfbe16149fa8f7385e0fdaea 485 PIRSF PIRSF006247 1 485 7.4E-162 T 14-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 Tharo_1147 fdc5c58c90cd572eb46089da5d751122 587 SUPERFAMILY SSF142019 172 373 2.35E-60 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1147 fdc5c58c90cd572eb46089da5d751122 587 SMART SM00928 478 523 1.0E-15 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1147 fdc5c58c90cd572eb46089da5d751122 587 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 312 327 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1147 fdc5c58c90cd572eb46089da5d751122 587 Gene3D G3DSA:3.40.30.10 92 175 7.3E-9 T 14-10-2018 Tharo_1147 fdc5c58c90cd572eb46089da5d751122 587 SUPERFAMILY SSF52833 18 180 6.04E-33 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_1147 fdc5c58c90cd572eb46089da5d751122 587 SUPERFAMILY SSF140490 481 554 1.05E-23 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1147 fdc5c58c90cd572eb46089da5d751122 587 Gene3D G3DSA:3.10.20.600 381 474 1.4E-24 T 14-10-2018 Tharo_1147 fdc5c58c90cd572eb46089da5d751122 587 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 32 160 2.7E-22 T 14-10-2018 Tharo_1147 fdc5c58c90cd572eb46089da5d751122 587 Gene3D G3DSA:1.10.10.1590 16 83 1.3E-9 T 14-10-2018 Tharo_1147 fdc5c58c90cd572eb46089da5d751122 587 SUPERFAMILY SSF142984 390 472 3.53E-21 T 14-10-2018 Tharo_1147 fdc5c58c90cd572eb46089da5d751122 587 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 481 554 2.2E-21 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1147 fdc5c58c90cd572eb46089da5d751122 587 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 204 363 1.8E-38 T 14-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1147 fdc5c58c90cd572eb46089da5d751122 587 Gene3D G3DSA:1.20.1440.230 478 561 1.7E-22 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1147 fdc5c58c90cd572eb46089da5d751122 587 Pfam PF10531 SLBB domain 392 441 2.2E-8 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1147 fdc5c58c90cd572eb46089da5d751122 587 Gene3D G3DSA:3.40.50.11540 208 380 6.1E-60 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1147 fdc5c58c90cd572eb46089da5d751122 587 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 491 502 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_0528 25ba7f6d7a20293b971c43e441797457 150 Pfam PF00581 Rhodanese-like domain 38 125 1.8E-9 T 14-10-2018 IPR001763 Rhodanese-like domain Tharo_0528 25ba7f6d7a20293b971c43e441797457 150 SMART SM00450 26 133 1.0E-6 T 14-10-2018 IPR001763 Rhodanese-like domain Tharo_0528 25ba7f6d7a20293b971c43e441797457 150 Gene3D G3DSA:3.40.250.10 20 150 1.3E-32 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Tharo_0528 25ba7f6d7a20293b971c43e441797457 150 SUPERFAMILY SSF52821 19 149 2.36E-20 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Tharo_3090 59552d5de5f1bd4e00d9ced1b9e35e86 144 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 30 63 8.7E-8 T 14-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal Tharo_3090 59552d5de5f1bd4e00d9ced1b9e35e86 144 SUPERFAMILY SSF50249 32 129 7.02E-22 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_3090 59552d5de5f1bd4e00d9ced1b9e35e86 144 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 65 123 5.2E-9 T 14-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal Tharo_1976 d2c451e1bec3eb0b38ee88c86d59fb57 230 Gene3D G3DSA:3.30.420.40 94 182 2.2E-55 T 14-10-2018 Tharo_1976 d2c451e1bec3eb0b38ee88c86d59fb57 230 SUPERFAMILY SSF53067 1 101 1.64E-22 T 14-10-2018 Tharo_1976 d2c451e1bec3eb0b38ee88c86d59fb57 230 Pfam PF00814 Glycoprotease family 31 146 1.7E-21 T 14-10-2018 IPR000905 Gcp-like domain Tharo_1976 d2c451e1bec3eb0b38ee88c86d59fb57 230 Gene3D G3DSA:3.30.420.40 3 216 2.2E-55 T 14-10-2018 Tharo_1976 d2c451e1bec3eb0b38ee88c86d59fb57 230 SUPERFAMILY SSF53067 105 211 2.98E-18 T 14-10-2018 Tharo_1976 d2c451e1bec3eb0b38ee88c86d59fb57 230 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 213 1.3E-47 T 14-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 Tharo_1658 05e58ff90d736cd879465b2c7835c4ad 312 Gene3D G3DSA:3.40.50.11270 15 99 3.3E-113 T 14-10-2018 Tharo_1658 05e58ff90d736cd879465b2c7835c4ad 312 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 5 284 8.3E-102 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 Tharo_1658 05e58ff90d736cd879465b2c7835c4ad 312 Gene3D G3DSA:3.40.1010.20 9 281 3.3E-113 T 14-10-2018 Tharo_1658 05e58ff90d736cd879465b2c7835c4ad 312 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 4 286 38.029 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 Tharo_1658 05e58ff90d736cd879465b2c7835c4ad 312 Gene3D G3DSA:3.40.1010.20 100 196 3.3E-113 T 14-10-2018 Tharo_1658 05e58ff90d736cd879465b2c7835c4ad 312 Pfam PF02401 LytB protein 6 282 1.1E-92 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 Tharo_0706 7a61b2a7b285a7858a20ab43079ed5c3 253 Pfam PF14348 Domain of unknown function (DUF4400) 51 250 2.2E-75 T 14-10-2018 IPR022266 Integrating conjugative element protein, PFL4697-type Tharo_0706 7a61b2a7b285a7858a20ab43079ed5c3 253 TIGRFAM TIGR03747 conj_TIGR03747: integrating conjugative element membrane protein, PFL_4697 family 15 253 1.7E-99 T 14-10-2018 IPR022266 Integrating conjugative element protein, PFL4697-type Tharo_2667 1c395152cde7a5380bd788f71841432f 511 Gene3D G3DSA:3.40.1190.20 217 492 9.4E-73 T 14-10-2018 IPR029056 Ribokinase-like Tharo_2667 1c395152cde7a5380bd788f71841432f 511 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 28 209 1.0E-40 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 Tharo_2667 1c395152cde7a5380bd788f71841432f 511 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 223 491 20.512 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 Tharo_2667 1c395152cde7a5380bd788f71841432f 511 SUPERFAMILY SSF53613 223 491 1.64E-64 T 14-10-2018 IPR029056 Ribokinase-like Tharo_2667 1c395152cde7a5380bd788f71841432f 511 Gene3D G3DSA:3.40.50.10260 8 214 1.0E-57 T 14-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 Tharo_2667 1c395152cde7a5380bd788f71841432f 511 Pfam PF03853 YjeF-related protein N-terminus 28 189 1.1E-43 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 Tharo_2667 1c395152cde7a5380bd788f71841432f 511 PIRSF PIRSF017184 12 492 2.6E-110 T 14-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 Tharo_2667 1c395152cde7a5380bd788f71841432f 511 SUPERFAMILY SSF64153 7 244 4.58E-56 T 14-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 Tharo_2667 1c395152cde7a5380bd788f71841432f 511 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 429 439 - T 14-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site Tharo_2667 1c395152cde7a5380bd788f71841432f 511 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 7 210 23.17 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 Tharo_2667 1c395152cde7a5380bd788f71841432f 511 Pfam PF01256 Carbohydrate kinase 247 470 2.6E-49 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 Tharo_2667 1c395152cde7a5380bd788f71841432f 511 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 229 485 3.7E-57 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 Tharo_2589 02deb1f3cfcd242ca58d883358bd0293 356 Pfam PF02913 FAD linked oxidases, C-terminal domain 329 351 4.6E-4 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 Tharo_2589 02deb1f3cfcd242ca58d883358bd0293 356 Gene3D G3DSA:3.30.465.10 51 170 1.5E-34 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Tharo_2589 02deb1f3cfcd242ca58d883358bd0293 356 Pfam PF01565 FAD binding domain 7 133 3.1E-19 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Tharo_2589 02deb1f3cfcd242ca58d883358bd0293 356 SUPERFAMILY SSF55103 176 353 3.92E-20 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 Tharo_2589 02deb1f3cfcd242ca58d883358bd0293 356 SUPERFAMILY SSF56176 7 171 6.07E-31 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Tharo_1015 18257f1a4d1b3c2d3a2410530aadccba 509 Gene3D G3DSA:3.40.50.150 68 265 7.7E-49 T 14-10-2018 Tharo_1015 18257f1a4d1b3c2d3a2410530aadccba 509 SUPERFAMILY SSF48452 348 468 6.13E-17 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_1015 18257f1a4d1b3c2d3a2410530aadccba 509 SMART SM00028 438 471 15.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Tharo_1015 18257f1a4d1b3c2d3a2410530aadccba 509 SMART SM00028 404 437 0.64 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Tharo_1015 18257f1a4d1b3c2d3a2410530aadccba 509 SMART SM00138 3 266 5.4E-62 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_1015 18257f1a4d1b3c2d3a2410530aadccba 509 Gene3D G3DSA:1.25.40.10 345 493 1.0E-18 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_1015 18257f1a4d1b3c2d3a2410530aadccba 509 SUPERFAMILY SSF53335 70 259 3.9E-40 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_1015 18257f1a4d1b3c2d3a2410530aadccba 509 PRINTS PR00996 Glutamate methyltransferase family signature 102 122 3.4E-24 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_1015 18257f1a4d1b3c2d3a2410530aadccba 509 PRINTS PR00996 Glutamate methyltransferase family signature 206 220 3.4E-24 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_1015 18257f1a4d1b3c2d3a2410530aadccba 509 PRINTS PR00996 Glutamate methyltransferase family signature 62 74 3.4E-24 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_1015 18257f1a4d1b3c2d3a2410530aadccba 509 PRINTS PR00996 Glutamate methyltransferase family signature 225 248 3.4E-24 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_1015 18257f1a4d1b3c2d3a2410530aadccba 509 PRINTS PR00996 Glutamate methyltransferase family signature 137 153 3.4E-24 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_1015 18257f1a4d1b3c2d3a2410530aadccba 509 SUPERFAMILY SSF47757 1 68 2.88E-5 T 14-10-2018 Tharo_1015 18257f1a4d1b3c2d3a2410530aadccba 509 Pfam PF01739 CheR methyltransferase, SAM binding domain 70 259 5.8E-47 T 14-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal Tharo_3026 eafa3d48cc3aa2f2f1a6fe151b0b1aa7 410 SUPERFAMILY SSF53756 18 390 4.19E-73 T 14-10-2018 Tharo_3026 eafa3d48cc3aa2f2f1a6fe151b0b1aa7 410 Gene3D G3DSA:3.40.50.2000 15 208 4.7E-26 T 14-10-2018 Tharo_3026 eafa3d48cc3aa2f2f1a6fe151b0b1aa7 410 Pfam PF13439 Glycosyltransferase Family 4 30 198 1.2E-20 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Tharo_3026 eafa3d48cc3aa2f2f1a6fe151b0b1aa7 410 Pfam PF00534 Glycosyl transferases group 1 209 368 1.4E-27 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 Tharo_3026 eafa3d48cc3aa2f2f1a6fe151b0b1aa7 410 Gene3D G3DSA:3.40.50.2000 209 371 8.4E-38 T 14-10-2018 Tharo_1685 495cc23e0076153b53b1149a8a9702ce 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.8E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1685 495cc23e0076153b53b1149a8a9702ce 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.8E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1685 495cc23e0076153b53b1149a8a9702ce 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.8E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1685 495cc23e0076153b53b1149a8a9702ce 308 SUPERFAMILY SSF46785 1 107 1.14E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1685 495cc23e0076153b53b1149a8a9702ce 308 Pfam PF03466 LysR substrate binding domain 91 291 9.2E-55 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_1685 495cc23e0076153b53b1149a8a9702ce 308 Gene3D G3DSA:1.10.10.10 1 86 4.5E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1685 495cc23e0076153b53b1149a8a9702ce 308 SUPERFAMILY SSF53850 91 295 2.17E-48 T 14-10-2018 Tharo_1685 495cc23e0076153b53b1149a8a9702ce 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 5.5E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1685 495cc23e0076153b53b1149a8a9702ce 308 Gene3D G3DSA:3.40.190.290 91 296 4.2E-48 T 14-10-2018 Tharo_1958 5d0770719595aff2f2c39c5cdb5398e4 690 SUPERFAMILY SSF56024 507 679 2.22E-66 T 14-10-2018 Tharo_1958 5d0770719595aff2f2c39c5cdb5398e4 690 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 12 681 1.4E-290 T 14-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 Tharo_1958 5d0770719595aff2f2c39c5cdb5398e4 690 SUPERFAMILY SSF140356 10 113 1.31E-36 T 14-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 Tharo_1958 5d0770719595aff2f2c39c5cdb5398e4 690 SUPERFAMILY SSF56024 322 499 2.61E-57 T 14-10-2018 Tharo_1958 5d0770719595aff2f2c39c5cdb5398e4 690 Hamap MF_00347 Polyphosphate kinase [ppk]. 9 688 27.807 T 14-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 Tharo_1958 5d0770719595aff2f2c39c5cdb5398e4 690 Gene3D G3DSA:3.30.870.10 507 688 2.5E-62 T 14-10-2018 Tharo_1958 5d0770719595aff2f2c39c5cdb5398e4 690 Pfam PF02503 Polyphosphate kinase middle domain 127 328 3.9E-60 T 14-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 Tharo_1958 5d0770719595aff2f2c39c5cdb5398e4 690 SUPERFAMILY SSF143724 115 320 7.65E-67 T 14-10-2018 Tharo_1958 5d0770719595aff2f2c39c5cdb5398e4 690 Gene3D G3DSA:3.30.1840.10 6 319 4.0E-104 T 14-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 Tharo_1958 5d0770719595aff2f2c39c5cdb5398e4 690 Pfam PF13089 Polyphosphate kinase N-terminal domain 12 117 1.0E-36 T 14-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 Tharo_1958 5d0770719595aff2f2c39c5cdb5398e4 690 Gene3D G3DSA:3.30.870.10 324 506 8.3E-73 T 14-10-2018 Tharo_1958 5d0770719595aff2f2c39c5cdb5398e4 690 Pfam PF13090 Polyphosphate kinase C-terminal domain 337 672 9.2E-149 T 14-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 Tharo_1958 5d0770719595aff2f2c39c5cdb5398e4 690 PIRSF PIRSF015589 2 690 9.0E-273 T 14-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 Tharo_1142 a07b0e3168197d18c21fffa3ecfe48fb 247 Pfam PF00005 ABC transporter 20 172 1.1E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_1142 a07b0e3168197d18c21fffa3ecfe48fb 247 SMART SM00382 26 220 3.6E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1142 a07b0e3168197d18c21fffa3ecfe48fb 247 SUPERFAMILY SSF52540 2 242 8.91E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1142 a07b0e3168197d18c21fffa3ecfe48fb 247 Gene3D G3DSA:3.40.50.300 2 247 1.2E-55 T 14-10-2018 Tharo_3364 a07b0e3168197d18c21fffa3ecfe48fb 247 Pfam PF00005 ABC transporter 20 172 1.1E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_3364 a07b0e3168197d18c21fffa3ecfe48fb 247 SMART SM00382 26 220 3.6E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_3364 a07b0e3168197d18c21fffa3ecfe48fb 247 SUPERFAMILY SSF52540 2 242 8.91E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3364 a07b0e3168197d18c21fffa3ecfe48fb 247 Gene3D G3DSA:3.40.50.300 2 247 1.2E-55 T 14-10-2018 Tharo_0390 bf2df119acb880b7d202d4f3795daa33 127 Gene3D G3DSA:1.20.58.380 6 94 1.8E-25 T 14-10-2018 Tharo_0390 bf2df119acb880b7d202d4f3795daa33 127 Pfam PF05400 Flagellar protein FliT 22 107 4.3E-18 T 14-10-2018 IPR008622 Flagellar protein FliT Tharo_1832 3e9de703b3c14b67e4d7dfdfd2c54ee0 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 256 263 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 Tharo_1832 3e9de703b3c14b67e4d7dfdfd2c54ee0 486 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 31 478 2.1E-223 T 14-10-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 Tharo_1832 3e9de703b3c14b67e4d7dfdfd2c54ee0 486 SUPERFAMILY SSF53720 9 483 1.3E-174 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Tharo_1832 3e9de703b3c14b67e4d7dfdfd2c54ee0 486 Gene3D G3DSA:3.40.309.10 260 449 2.1E-187 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Tharo_1832 3e9de703b3c14b67e4d7dfdfd2c54ee0 486 Gene3D G3DSA:3.40.605.10 26 474 2.1E-187 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Tharo_1832 3e9de703b3c14b67e4d7dfdfd2c54ee0 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 284 295 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 Tharo_1832 3e9de703b3c14b67e4d7dfdfd2c54ee0 486 Pfam PF00171 Aldehyde dehydrogenase family 21 479 2.6E-174 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Tharo_2860 a9940283a3784f606ad83843ca4ea756 113 SUPERFAMILY SSF55008 43 87 1.19E-5 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 Tharo_0139 26160130f6ad61b9cbfe5765276db439 652 Hamap MF_02081 Peptidoglycan D,D-transpeptidase MrdA [mrdA]. 3 614 49.51 T 14-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Tharo_0139 26160130f6ad61b9cbfe5765276db439 652 Gene3D G3DSA:3.90.1310.10 62 244 1.3E-44 T 14-10-2018 Tharo_0139 26160130f6ad61b9cbfe5765276db439 652 Pfam PF03717 Penicillin-binding Protein dimerisation domain 62 235 7.0E-43 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 Tharo_0139 26160130f6ad61b9cbfe5765276db439 652 Pfam PF00905 Penicillin binding protein transpeptidase domain 268 607 1.0E-79 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Tharo_0139 26160130f6ad61b9cbfe5765276db439 652 SUPERFAMILY SSF56519 53 250 1.23E-48 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 Tharo_0139 26160130f6ad61b9cbfe5765276db439 652 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 17 611 8.6E-237 T 14-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Tharo_0139 26160130f6ad61b9cbfe5765276db439 652 Gene3D G3DSA:3.40.710.10 245 620 1.3E-106 T 14-10-2018 Tharo_0139 26160130f6ad61b9cbfe5765276db439 652 SUPERFAMILY SSF56601 251 610 1.82E-105 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Tharo_0139 26160130f6ad61b9cbfe5765276db439 652 Gene3D G3DSA:3.30.1390.30 82 157 1.3E-44 T 14-10-2018 Tharo_1200 1b3f3cbdfbd4346a2b012719f11a5900 461 Gene3D G3DSA:1.20.120.640 309 461 1.6E-42 T 14-10-2018 Tharo_1200 1b3f3cbdfbd4346a2b012719f11a5900 461 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 15 316 3.7E-128 T 14-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 Tharo_1200 1b3f3cbdfbd4346a2b012719f11a5900 461 Gene3D G3DSA:3.40.50.620 1 308 3.4E-133 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_1200 1b3f3cbdfbd4346a2b012719f11a5900 461 SMART SM00840 346 401 5.0E-25 T 14-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 Tharo_1200 1b3f3cbdfbd4346a2b012719f11a5900 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 225 246 4.3E-30 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Tharo_1200 1b3f3cbdfbd4346a2b012719f11a5900 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 4.3E-30 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Tharo_1200 1b3f3cbdfbd4346a2b012719f11a5900 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 4.3E-30 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Tharo_1200 1b3f3cbdfbd4346a2b012719f11a5900 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 194 212 4.3E-30 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Tharo_1200 1b3f3cbdfbd4346a2b012719f11a5900 461 Pfam PF09190 DALR domain 346 401 6.1E-19 T 14-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 Tharo_1200 1b3f3cbdfbd4346a2b012719f11a5900 461 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 461 38.662 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 Tharo_1200 1b3f3cbdfbd4346a2b012719f11a5900 461 SUPERFAMILY SSF47323 319 460 8.37E-36 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_1200 1b3f3cbdfbd4346a2b012719f11a5900 461 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 460 2.7E-168 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 Tharo_1200 1b3f3cbdfbd4346a2b012719f11a5900 461 SUPERFAMILY SSF52374 2 317 5.63E-101 T 14-10-2018 Tharo_2394 e17d6ad5bf6479332a00e9ce8ec267f0 329 Gene3D G3DSA:3.40.50.720 2 185 3.5E-53 T 14-10-2018 Tharo_2394 e17d6ad5bf6479332a00e9ce8ec267f0 329 SUPERFAMILY SSF48179 177 329 9.98E-54 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Tharo_2394 e17d6ad5bf6479332a00e9ce8ec267f0 329 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 171 195 2.6E-39 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Tharo_2394 e17d6ad5bf6479332a00e9ce8ec267f0 329 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 56 83 2.6E-39 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Tharo_2394 e17d6ad5bf6479332a00e9ce8ec267f0 329 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 7 24 2.6E-39 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Tharo_2394 e17d6ad5bf6479332a00e9ce8ec267f0 329 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 236 253 2.6E-39 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Tharo_2394 e17d6ad5bf6479332a00e9ce8ec267f0 329 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 131 151 2.6E-39 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Tharo_2394 e17d6ad5bf6479332a00e9ce8ec267f0 329 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 196 220 2.6E-39 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Tharo_2394 e17d6ad5bf6479332a00e9ce8ec267f0 329 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 186 207 - T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Tharo_2394 e17d6ad5bf6479332a00e9ce8ec267f0 329 Gene3D G3DSA:1.10.1040.10 187 329 3.1E-49 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Tharo_2394 e17d6ad5bf6479332a00e9ce8ec267f0 329 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 4 158 1.8E-41 T 14-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Tharo_2394 e17d6ad5bf6479332a00e9ce8ec267f0 329 PIRSF PIRSF000114 2 329 2.7E-94 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Tharo_2394 e17d6ad5bf6479332a00e9ce8ec267f0 329 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 3 320 36.441 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Tharo_2394 e17d6ad5bf6479332a00e9ce8ec267f0 329 SUPERFAMILY SSF51735 4 178 1.22E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_2394 e17d6ad5bf6479332a00e9ce8ec267f0 329 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 178 318 1.4E-49 T 14-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Tharo_1422 65723762a81553f54ca99e02bee03abc 465 Pfam PF12801 4Fe-4S binding domain 89 128 4.9E-9 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_1422 65723762a81553f54ca99e02bee03abc 465 SUPERFAMILY SSF54862 99 337 6.98E-30 T 14-10-2018 Tharo_1422 65723762a81553f54ca99e02bee03abc 465 Pfam PF13746 4Fe-4S dicluster domain 214 313 9.2E-38 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_1422 65723762a81553f54ca99e02bee03abc 465 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 31 462 1.5E-138 T 14-10-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 Tharo_1422 65723762a81553f54ca99e02bee03abc 465 Gene3D G3DSA:3.30.70.20 209 280 7.6E-6 T 14-10-2018 Tharo_1422 65723762a81553f54ca99e02bee03abc 465 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 261 272 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_1422 65723762a81553f54ca99e02bee03abc 465 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 348 463 5.4E-26 T 14-10-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain Tharo_1422 65723762a81553f54ca99e02bee03abc 465 Gene3D G3DSA:2.60.40.10 348 463 9.7E-25 T 14-10-2018 IPR013783 Immunoglobulin-like fold Tharo_2204 3cf8d50222e420dd28b78c4b5c9e1f04 339 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 4 329 4.1E-110 T 14-10-2018 IPR011303 Ion-translocating oxidoreductase complex Rnf, subunit D GO:0016021|GO:0022900 Tharo_2204 3cf8d50222e420dd28b78c4b5c9e1f04 339 Pfam PF03116 NQR2, RnfD, RnfE family 3 328 5.0E-96 T 14-10-2018 IPR004338 Ion-translocating oxidoreductase NqrB/RnfD GO:0016020|GO:0055085 Tharo_2204 3cf8d50222e420dd28b78c4b5c9e1f04 339 Hamap MF_00462 Ion-translocating oxidoreductase complex subunit D [rsxD]. 1 330 24.142 T 14-10-2018 IPR011303 Ion-translocating oxidoreductase complex Rnf, subunit D GO:0016021|GO:0022900 Tharo_0787 55e904ec8039c3fa11eb1a8f765daec0 560 Gene3D G3DSA:3.30.413.10 408 559 6.1E-35 T 14-10-2018 Tharo_0787 55e904ec8039c3fa11eb1a8f765daec0 560 SUPERFAMILY SSF55124 1 126 3.27E-27 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Tharo_0787 55e904ec8039c3fa11eb1a8f765daec0 560 Gene3D G3DSA:3.90.480.20 43 111 1.2E-57 T 14-10-2018 Tharo_0787 55e904ec8039c3fa11eb1a8f765daec0 560 Gene3D G3DSA:3.90.480.20 315 398 1.5E-14 T 14-10-2018 Tharo_0787 55e904ec8039c3fa11eb1a8f765daec0 560 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 53 110 5.8E-13 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Tharo_0787 55e904ec8039c3fa11eb1a8f765daec0 560 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 328 399 3.1E-16 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Tharo_0787 55e904ec8039c3fa11eb1a8f765daec0 560 SUPERFAMILY SSF55124 252 421 4.91E-25 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Tharo_0787 55e904ec8039c3fa11eb1a8f765daec0 560 SUPERFAMILY SSF56014 409 554 1.3E-42 T 14-10-2018 Tharo_0787 55e904ec8039c3fa11eb1a8f765daec0 560 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 413 549 1.2E-13 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Tharo_0787 55e904ec8039c3fa11eb1a8f765daec0 560 SUPERFAMILY SSF56014 120 278 7.72E-47 T 14-10-2018 Tharo_0787 55e904ec8039c3fa11eb1a8f765daec0 560 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 119 273 3.5E-40 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Tharo_0787 55e904ec8039c3fa11eb1a8f765daec0 560 Gene3D G3DSA:3.30.413.10 112 275 1.2E-57 T 14-10-2018 Tharo_3247 73ab05eda5b823991810528a3c4afea7 379 Pfam PF00534 Glycosyl transferases group 1 194 348 1.1E-33 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 Tharo_3247 73ab05eda5b823991810528a3c4afea7 379 SUPERFAMILY SSF53756 4 367 6.57E-60 T 14-10-2018 Tharo_3247 73ab05eda5b823991810528a3c4afea7 379 Gene3D G3DSA:3.40.50.2000 12 169 1.8E-109 T 14-10-2018 Tharo_3247 73ab05eda5b823991810528a3c4afea7 379 Gene3D G3DSA:3.40.50.2000 170 333 1.8E-109 T 14-10-2018 Tharo_1021 be326e8e0bd499bbbc6b1ca7133793ee 921 Pfam PF02743 Cache domain 372 560 3.5E-15 T 14-10-2018 IPR033479 Double Cache domain 1 Tharo_1021 be326e8e0bd499bbbc6b1ca7133793ee 921 SUPERFAMILY SSF55073 750 906 3.61E-47 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_1021 be326e8e0bd499bbbc6b1ca7133793ee 921 Pfam PF03924 CHASE domain 108 214 6.4E-16 T 14-10-2018 IPR006189 CHASE domain Tharo_1021 be326e8e0bd499bbbc6b1ca7133793ee 921 Gene3D G3DSA:1.20.1480.50 635 728 8.0E-7 T 14-10-2018 Tharo_1021 be326e8e0bd499bbbc6b1ca7133793ee 921 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 742 908 3.2E-52 T 14-10-2018 IPR000160 GGDEF domain Tharo_1021 be326e8e0bd499bbbc6b1ca7133793ee 921 Gene3D G3DSA:3.30.70.270 730 909 3.3E-57 T 14-10-2018 Tharo_1021 be326e8e0bd499bbbc6b1ca7133793ee 921 Pfam PF00990 Diguanylate cyclase, GGDEF domain 746 905 6.8E-51 T 14-10-2018 IPR000160 GGDEF domain Tharo_1021 be326e8e0bd499bbbc6b1ca7133793ee 921 SMART SM00304 668 721 3.7E-4 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_1021 be326e8e0bd499bbbc6b1ca7133793ee 921 Gene3D G3DSA:3.30.450.20 385 526 3.7E-10 T 14-10-2018 Tharo_1021 be326e8e0bd499bbbc6b1ca7133793ee 921 SMART SM00267 734 909 1.2E-67 T 14-10-2018 IPR000160 GGDEF domain Tharo_1021 be326e8e0bd499bbbc6b1ca7133793ee 921 SMART SM01079 62 226 9.1E-21 T 14-10-2018 IPR006189 CHASE domain Tharo_1505 3d0aefb3c91f121c6ce291b965cd8668 234 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 31 220 3.6E-47 T 14-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 Tharo_1505 3d0aefb3c91f121c6ce291b965cd8668 234 SUPERFAMILY SSF52540 30 230 2.92E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1505 3d0aefb3c91f121c6ce291b965cd8668 234 Hamap MF_00165 Thymidylate kinase [tmk]. 33 232 28.137 T 14-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 Tharo_1505 3d0aefb3c91f121c6ce291b965cd8668 234 Pfam PF02223 Thymidylate kinase 37 224 1.9E-44 T 14-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 Tharo_1505 3d0aefb3c91f121c6ce291b965cd8668 234 Gene3D G3DSA:3.40.50.300 29 232 2.5E-61 T 14-10-2018 Tharo_2433 8e7cff8ab0e95f47c30b6bfb7c58cde2 802 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 19 69 1.8E-6 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_2433 8e7cff8ab0e95f47c30b6bfb7c58cde2 802 Pfam PF01568 Molydopterin dinucleotide binding domain 671 790 9.0E-21 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 Tharo_2433 8e7cff8ab0e95f47c30b6bfb7c58cde2 802 Gene3D G3DSA:3.40.228.10 164 265 7.7E-55 T 14-10-2018 Tharo_2433 8e7cff8ab0e95f47c30b6bfb7c58cde2 802 SUPERFAMILY SSF53706 18 650 3.99E-142 T 14-10-2018 Tharo_2433 8e7cff8ab0e95f47c30b6bfb7c58cde2 802 SUPERFAMILY SSF50692 628 799 1.08E-34 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Tharo_2433 8e7cff8ab0e95f47c30b6bfb7c58cde2 802 Gene3D G3DSA:2.20.25.90 11 73 4.6E-11 T 14-10-2018 Tharo_2433 8e7cff8ab0e95f47c30b6bfb7c58cde2 802 Gene3D G3DSA:3.40.228.10 345 643 5.5E-58 T 14-10-2018 Tharo_2433 8e7cff8ab0e95f47c30b6bfb7c58cde2 802 SMART SM00926 17 70 2.4E-9 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_2433 8e7cff8ab0e95f47c30b6bfb7c58cde2 802 Gene3D G3DSA:3.40.50.740 455 580 5.5E-58 T 14-10-2018 Tharo_2433 8e7cff8ab0e95f47c30b6bfb7c58cde2 802 Gene3D G3DSA:3.40.50.740 74 163 7.7E-55 T 14-10-2018 Tharo_2433 8e7cff8ab0e95f47c30b6bfb7c58cde2 802 Gene3D G3DSA:3.30.2070.10 530 615 5.5E-58 T 14-10-2018 Tharo_2433 8e7cff8ab0e95f47c30b6bfb7c58cde2 802 Pfam PF00384 Molybdopterin oxidoreductase 73 575 1.1E-46 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_2433 8e7cff8ab0e95f47c30b6bfb7c58cde2 802 Gene3D G3DSA:2.40.40.20 645 798 1.5E-35 T 14-10-2018 Tharo_2433 8e7cff8ab0e95f47c30b6bfb7c58cde2 802 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 515 532 - T 14-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 Tharo_3328 811272dc429e8a1ccca5bf9a85c13e79 298 SMART SM00864 2 186 2.3E-32 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Tharo_3328 811272dc429e8a1ccca5bf9a85c13e79 298 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 24 148 7.1E-22 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Tharo_3328 811272dc429e8a1ccca5bf9a85c13e79 298 Gene3D G3DSA:3.40.50.1440 1 297 4.1E-63 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 Tharo_3328 811272dc429e8a1ccca5bf9a85c13e79 298 SUPERFAMILY SSF52490 2 189 6.28E-36 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 Tharo_3328 811272dc429e8a1ccca5bf9a85c13e79 298 PRINTS PR00423 Cell division protein FtsZ signature 108 129 4.3E-16 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Tharo_3328 811272dc429e8a1ccca5bf9a85c13e79 298 PRINTS PR00423 Cell division protein FtsZ signature 80 100 4.3E-16 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Tharo_3328 811272dc429e8a1ccca5bf9a85c13e79 298 PRINTS PR00423 Cell division protein FtsZ signature 170 192 4.3E-16 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Tharo_3328 811272dc429e8a1ccca5bf9a85c13e79 298 ProSitePatterns PS01135 FtsZ protein signature 2. 79 100 - T 14-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 Tharo_3328 811272dc429e8a1ccca5bf9a85c13e79 298 SUPERFAMILY SSF55307 185 297 3.2E-7 T 14-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 Tharo_2957 f7698d385c827a70fd51402ed249aff0 509 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 4 435 3.3E-175 T 14-10-2018 IPR010232 Probable protein kinase UbiB GO:0006744 Tharo_2957 f7698d385c827a70fd51402ed249aff0 509 Pfam PF03109 ABC1 family 109 225 5.3E-35 T 14-10-2018 IPR004147 UbiB domain Tharo_2957 f7698d385c827a70fd51402ed249aff0 509 Hamap MF_00414 Probable protein kinase UbiB [ubiB]. 1 505 50.127 T 14-10-2018 IPR010232 Probable protein kinase UbiB GO:0006744 Tharo_2957 f7698d385c827a70fd51402ed249aff0 509 SUPERFAMILY SSF56112 89 427 1.75E-48 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Tharo_0396 1083a0eb7ddff752581d3030cb25fc45 316 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 17 68 7.1E-17 T 14-10-2018 IPR025713 Motility protein B, N-terminal domain Tharo_0396 1083a0eb7ddff752581d3030cb25fc45 316 SUPERFAMILY SSF103088 160 268 2.75E-17 T 14-10-2018 IPR036737 OmpA-like domain superfamily Tharo_0396 1083a0eb7ddff752581d3030cb25fc45 316 Pfam PF00691 OmpA family 164 254 1.8E-6 T 14-10-2018 IPR006665 OmpA-like domain Tharo_0396 1083a0eb7ddff752581d3030cb25fc45 316 Gene3D G3DSA:3.30.1330.60 112 286 1.1E-45 T 14-10-2018 IPR036737 OmpA-like domain superfamily Tharo_1983 5356be2a4b5207a8b4d1a011aa08e632 148 Gene3D G3DSA:3.40.50.1450 4 148 1.2E-21 T 14-10-2018 IPR023430 Peptidase HybD-like domain superfamily Tharo_1983 5356be2a4b5207a8b4d1a011aa08e632 148 SUPERFAMILY SSF53163 4 145 9.02E-24 T 14-10-2018 IPR023430 Peptidase HybD-like domain superfamily Tharo_1983 5356be2a4b5207a8b4d1a011aa08e632 148 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 6 143 1.4E-18 T 14-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 Tharo_1558 933789983069bdb3824eb4d14e0e542c 310 PIRSF PIRSF001438 1 310 4.3E-114 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Tharo_1558 933789983069bdb3824eb4d14e0e542c 310 PRINTS PR00151 Porphobilinogen deaminase signature 48 68 6.8E-45 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Tharo_1558 933789983069bdb3824eb4d14e0e542c 310 PRINTS PR00151 Porphobilinogen deaminase signature 146 163 6.8E-45 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Tharo_1558 933789983069bdb3824eb4d14e0e542c 310 PRINTS PR00151 Porphobilinogen deaminase signature 127 144 6.8E-45 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Tharo_1558 933789983069bdb3824eb4d14e0e542c 310 PRINTS PR00151 Porphobilinogen deaminase signature 79 98 6.8E-45 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Tharo_1558 933789983069bdb3824eb4d14e0e542c 310 PRINTS PR00151 Porphobilinogen deaminase signature 233 250 6.8E-45 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Tharo_1558 933789983069bdb3824eb4d14e0e542c 310 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 229 298 1.2E-17 T 14-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Tharo_1558 933789983069bdb3824eb4d14e0e542c 310 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 234 250 - T 14-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Tharo_1558 933789983069bdb3824eb4d14e0e542c 310 Gene3D G3DSA:3.40.190.10 106 205 7.0E-79 T 14-10-2018 Tharo_1558 933789983069bdb3824eb4d14e0e542c 310 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 9 300 6.3E-103 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Tharo_1558 933789983069bdb3824eb4d14e0e542c 310 SUPERFAMILY SSF53850 8 222 3.31E-81 T 14-10-2018 Tharo_1558 933789983069bdb3824eb4d14e0e542c 310 Gene3D G3DSA:3.40.190.10 9 211 7.0E-79 T 14-10-2018 Tharo_1558 933789983069bdb3824eb4d14e0e542c 310 SUPERFAMILY SSF54782 224 308 4.18E-24 T 14-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Tharo_1558 933789983069bdb3824eb4d14e0e542c 310 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 8 300 37.166 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Tharo_1558 933789983069bdb3824eb4d14e0e542c 310 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 9 215 2.0E-73 T 14-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Tharo_1558 933789983069bdb3824eb4d14e0e542c 310 Gene3D G3DSA:3.30.160.40 224 309 6.4E-26 T 14-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Tharo_0060 26011f192bc9af0d05cb75918af13b67 542 Gene3D G3DSA:3.40.50.970 343 541 3.0E-52 T 14-10-2018 Tharo_0060 26011f192bc9af0d05cb75918af13b67 542 SUPERFAMILY SSF52518 1 180 1.21E-36 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_0060 26011f192bc9af0d05cb75918af13b67 542 Gene3D G3DSA:3.40.50.970 1 180 3.1E-60 T 14-10-2018 Tharo_0060 26011f192bc9af0d05cb75918af13b67 542 TIGRFAM TIGR03394 indol_phenyl_DC: indolepyruvate/phenylpyruvate decarboxylase 2 531 7.9E-268 T 14-10-2018 IPR017765 Indole-3-pyruvate decarboxylase GO:0009851|GO:0047434 KEGG: 00380+4.1.1.74|MetaCyc: PWY-5081 Tharo_0060 26011f192bc9af0d05cb75918af13b67 542 SUPERFAMILY SSF52518 347 525 2.09E-38 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_0060 26011f192bc9af0d05cb75918af13b67 542 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 173 2.5E-40 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Tharo_0060 26011f192bc9af0d05cb75918af13b67 542 Gene3D G3DSA:3.40.50.1220 183 339 1.1E-49 T 14-10-2018 Tharo_0060 26011f192bc9af0d05cb75918af13b67 542 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 290 1.8E-17 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 Tharo_0060 26011f192bc9af0d05cb75918af13b67 542 SUPERFAMILY SSF52467 162 332 6.54E-28 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Tharo_0060 26011f192bc9af0d05cb75918af13b67 542 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 378 515 4.1E-24 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Tharo_0060 26011f192bc9af0d05cb75918af13b67 542 PIRSF PIRSF036565 1 538 1.2E-128 T 14-10-2018 IPR012110 Thiamine pyrophosphate (TPP)-dependent enzyme GO:0016831 Tharo_3186 9356590e6f60b1d1f04b0c9250aa66b5 197 Pfam PF03167 Uracil DNA glycosylase superfamily 8 161 2.8E-9 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Tharo_3186 9356590e6f60b1d1f04b0c9250aa66b5 197 Gene3D G3DSA:3.40.470.10 1 166 8.0E-51 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Tharo_3186 9356590e6f60b1d1f04b0c9250aa66b5 197 TIGRFAM TIGR04274 hypoxanDNAglyco: DNA-deoxyinosine glycosylase 3 157 7.6E-46 T 14-10-2018 IPR026353 Hypoxanthine-DNA glycosylase Tharo_3186 9356590e6f60b1d1f04b0c9250aa66b5 197 SMART SM00987 5 161 6.4E-14 T 14-10-2018 Tharo_3186 9356590e6f60b1d1f04b0c9250aa66b5 197 SUPERFAMILY SSF52141 4 161 3.66E-36 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Tharo_3186 9356590e6f60b1d1f04b0c9250aa66b5 197 SMART SM00986 5 161 6.4E-14 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Tharo_3000 f723d7e913e71c8f781bccdf336a24d0 580 Pfam PF06980 Protein of unknown function (DUF1302) 26 580 7.0E-150 T 14-10-2018 IPR010727 Protein of unknown function DUF1302 Tharo_3000 f723d7e913e71c8f781bccdf336a24d0 580 SUPERFAMILY SSF56935 155 385 1.2E-6 T 14-10-2018 Tharo_2484 b5e583d0b0730f68a42cfacfc00f2bb8 623 Gene3D G3DSA:1.10.860.10 467 616 1.5E-14 T 14-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal Tharo_2484 b5e583d0b0730f68a42cfacfc00f2bb8 623 Gene3D G3DSA:3.90.980.10 106 232 1.6E-40 T 14-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily Tharo_2484 b5e583d0b0730f68a42cfacfc00f2bb8 623 SUPERFAMILY SSF56731 112 415 1.57E-103 T 14-10-2018 Tharo_2484 b5e583d0b0730f68a42cfacfc00f2bb8 623 Pfam PF08278 DNA primase DnaG DnaB-binding 483 607 9.7E-21 T 14-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 Tharo_2484 b5e583d0b0730f68a42cfacfc00f2bb8 623 SUPERFAMILY SSF57783 1 95 3.91E-38 T 14-10-2018 Tharo_2484 b5e583d0b0730f68a42cfacfc00f2bb8 623 SUPERFAMILY SSF117023 478 611 2.75E-22 T 14-10-2018 Tharo_2484 b5e583d0b0730f68a42cfacfc00f2bb8 623 Pfam PF10410 DnaB-helicase binding domain of primase 363 415 6.9E-13 T 14-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 Tharo_2484 b5e583d0b0730f68a42cfacfc00f2bb8 623 SMART SM00400 33 87 1.2E-34 T 14-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 Tharo_2484 b5e583d0b0730f68a42cfacfc00f2bb8 623 SMART SM00493 251 322 4.1E-18 T 14-10-2018 IPR006171 TOPRIM domain Tharo_2484 b5e583d0b0730f68a42cfacfc00f2bb8 623 Gene3D G3DSA:3.90.580.10 1 97 4.2E-39 T 14-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 Tharo_2484 b5e583d0b0730f68a42cfacfc00f2bb8 623 Pfam PF13662 Toprim domain 253 317 2.5E-16 T 14-10-2018 IPR006171 TOPRIM domain Tharo_2484 b5e583d0b0730f68a42cfacfc00f2bb8 623 Pfam PF08275 DNA primase catalytic core, N-terminal domain 122 243 6.5E-39 T 14-10-2018 IPR013264 DNA primase, catalytic core, N-terminal Tharo_2484 b5e583d0b0730f68a42cfacfc00f2bb8 623 Hamap MF_00974 DNA primase [dnaG]. 1 609 28.263 T 14-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 Tharo_2484 b5e583d0b0730f68a42cfacfc00f2bb8 623 TIGRFAM TIGR01391 dnaG: DNA primase 1 410 1.6E-143 T 14-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 Tharo_2484 b5e583d0b0730f68a42cfacfc00f2bb8 623 Gene3D G3DSA:3.40.1360.10 233 359 6.9E-42 T 14-10-2018 Tharo_2484 b5e583d0b0730f68a42cfacfc00f2bb8 623 Pfam PF01807 CHC2 zinc finger 3 96 5.5E-38 T 14-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 Tharo_2484 b5e583d0b0730f68a42cfacfc00f2bb8 623 SMART SM00766 480 608 7.9E-26 T 14-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 Tharo_0634 115bbbb449cd752558b283e43475bb38 214 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 4 189 5.9E-58 T 14-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 Tharo_0634 115bbbb449cd752558b283e43475bb38 214 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 148 169 - T 14-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 Tharo_0634 115bbbb449cd752558b283e43475bb38 214 Pfam PF01634 ATP phosphoribosyltransferase 53 207 3.5E-49 T 14-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 Tharo_0634 115bbbb449cd752558b283e43475bb38 214 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 3 213 56.442 T 14-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 Tharo_0634 115bbbb449cd752558b283e43475bb38 214 Gene3D G3DSA:3.40.190.10 95 181 3.2E-70 T 14-10-2018 Tharo_0634 115bbbb449cd752558b283e43475bb38 214 Gene3D G3DSA:3.40.190.10 5 201 3.2E-70 T 14-10-2018 Tharo_0634 115bbbb449cd752558b283e43475bb38 214 SUPERFAMILY SSF53850 4 208 1.09E-64 T 14-10-2018 Tharo_1025 554106bac4f7baebbd6c80b4c9390442 403 Pfam PF02353 Mycolic acid cyclopropane synthetase 124 388 4.3E-89 T 14-10-2018 Tharo_1025 554106bac4f7baebbd6c80b4c9390442 403 Gene3D G3DSA:3.40.50.150 133 396 8.0E-93 T 14-10-2018 Tharo_1025 554106bac4f7baebbd6c80b4c9390442 403 SUPERFAMILY SSF53335 135 390 4.89E-73 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_1025 554106bac4f7baebbd6c80b4c9390442 403 PIRSF PIRSF003085 23 398 2.8E-112 T 14-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 Tharo_2075 1eedf3c7b30f869309a500df26ee7f1f 1208 SUPERFAMILY SSF75553 505 706 1.57E-6 T 14-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 Tharo_2075 1eedf3c7b30f869309a500df26ee7f1f 1208 Hamap MF_01894 Chromosome partition protein Smc [smc]. 25 1198 22.082 T 14-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 Tharo_2075 1eedf3c7b30f869309a500df26ee7f1f 1208 Pfam PF06470 SMC proteins Flexible Hinge Domain 547 654 5.4E-5 T 14-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 Tharo_2075 1eedf3c7b30f869309a500df26ee7f1f 1208 SUPERFAMILY SSF57997 378 529 4.58E-6 T 14-10-2018 Tharo_2075 1eedf3c7b30f869309a500df26ee7f1f 1208 SUPERFAMILY SSF52540 26 1199 8.91E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2075 1eedf3c7b30f869309a500df26ee7f1f 1208 Gene3D G3DSA:3.40.50.300 25 272 1.6E-45 T 14-10-2018 Tharo_2075 1eedf3c7b30f869309a500df26ee7f1f 1208 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 26 1196 0.0 T 14-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 Tharo_2075 1eedf3c7b30f869309a500df26ee7f1f 1208 Gene3D G3DSA:3.40.50.300 1044 1207 6.9E-48 T 14-10-2018 Tharo_2075 1eedf3c7b30f869309a500df26ee7f1f 1208 PIRSF PIRSF005719 25 1204 1.9E-239 T 14-10-2018 IPR024704 Structural maintenance of chromosomes protein Tharo_2075 1eedf3c7b30f869309a500df26ee7f1f 1208 Pfam PF02463 RecF/RecN/SMC N terminal domain 27 1189 1.8E-63 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal Tharo_2410 34cf11e869e3d5911e3589e6df876201 269 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 215 229 - T 14-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 Tharo_2410 34cf11e869e3d5911e3589e6df876201 269 Gene3D G3DSA:3.30.540.10 11 148 2.8E-35 T 14-10-2018 Tharo_2410 34cf11e869e3d5911e3589e6df876201 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 138 161 1.4E-21 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Tharo_2410 34cf11e869e3d5911e3589e6df876201 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 89 105 1.4E-21 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Tharo_2410 34cf11e869e3d5911e3589e6df876201 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 212 236 1.4E-21 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Tharo_2410 34cf11e869e3d5911e3589e6df876201 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 181 202 1.4E-21 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Tharo_2410 34cf11e869e3d5911e3589e6df876201 269 SUPERFAMILY SSF56655 20 268 1.57E-64 T 14-10-2018 Tharo_2410 34cf11e869e3d5911e3589e6df876201 269 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 89 102 - T 14-10-2018 IPR020583 Inositol monophosphatase, metal-binding site Tharo_2410 34cf11e869e3d5911e3589e6df876201 269 Gene3D G3DSA:3.40.190.80 151 268 2.1E-22 T 14-10-2018 Tharo_2410 34cf11e869e3d5911e3589e6df876201 269 Pfam PF00459 Inositol monophosphatase family 25 254 2.6E-48 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Tharo_1263 fef6c36d54ee54ee082c29030f40d20d 355 SUPERFAMILY SSF63380 3 105 1.43E-27 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Tharo_1263 fef6c36d54ee54ee082c29030f40d20d 355 SUPERFAMILY SSF54292 235 351 5.12E-28 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Tharo_1263 fef6c36d54ee54ee082c29030f40d20d 355 Gene3D G3DSA:3.40.50.80 109 247 2.3E-32 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_1263 fef6c36d54ee54ee082c29030f40d20d 355 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 271 343 8.7E-15 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Tharo_1263 fef6c36d54ee54ee082c29030f40d20d 355 Pfam PF00970 Oxidoreductase FAD-binding domain 8 105 5.9E-15 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 Tharo_1263 fef6c36d54ee54ee082c29030f40d20d 355 Pfam PF00175 Oxidoreductase NAD-binding domain 120 227 2.2E-15 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 Tharo_1263 fef6c36d54ee54ee082c29030f40d20d 355 Gene3D G3DSA:3.10.20.30 248 355 3.5E-26 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Tharo_1263 fef6c36d54ee54ee082c29030f40d20d 355 Gene3D G3DSA:2.40.30.10 3 105 4.2E-25 T 14-10-2018 Tharo_1263 fef6c36d54ee54ee082c29030f40d20d 355 PRINTS PR00410 Phenol hydroxylase reductase family signature 142 151 2.4E-5 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 Tharo_1263 fef6c36d54ee54ee082c29030f40d20d 355 PRINTS PR00410 Phenol hydroxylase reductase family signature 117 136 2.4E-5 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 Tharo_1263 fef6c36d54ee54ee082c29030f40d20d 355 PRINTS PR00410 Phenol hydroxylase reductase family signature 213 221 2.4E-5 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 Tharo_1263 fef6c36d54ee54ee082c29030f40d20d 355 PRINTS PR00410 Phenol hydroxylase reductase family signature 37 49 2.4E-5 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 Tharo_1263 fef6c36d54ee54ee082c29030f40d20d 355 TIGRFAM TIGR02160 PA_CoA_Oxy5: phenylacetate-CoA oxygenase/reductase, PaaK subunit 5 353 8.7E-168 T 14-10-2018 IPR011884 Phenylacetate-CoA oxygenase/reductase, PaaK subunit GO:0010124 Tharo_1263 fef6c36d54ee54ee082c29030f40d20d 355 SUPERFAMILY SSF52343 95 243 1.7E-34 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_1882 778fa7f9c6f6a180850f1dde2fb8ad85 439 Pfam PF01979 Amidohydrolase family 61 409 1.6E-69 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Tharo_1882 778fa7f9c6f6a180850f1dde2fb8ad85 439 SUPERFAMILY SSF51556 64 363 2.25E-100 T 14-10-2018 IPR032466 Metal-dependent hydrolase Tharo_1882 778fa7f9c6f6a180850f1dde2fb8ad85 439 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 6 438 39.36 T 14-10-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 Tharo_1882 778fa7f9c6f6a180850f1dde2fb8ad85 439 SUPERFAMILY SSF51338 6 435 6.84E-20 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Tharo_1882 778fa7f9c6f6a180850f1dde2fb8ad85 439 Gene3D G3DSA:2.30.40.10 15 428 1.3E-160 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Tharo_1882 778fa7f9c6f6a180850f1dde2fb8ad85 439 Gene3D G3DSA:3.20.20.140 65 355 1.3E-160 T 14-10-2018 Tharo_1840 d2cc998f81b3696f29f08a09297356f5 453 Pfam PF00158 Sigma-54 interaction domain 151 316 1.1E-65 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Tharo_1840 d2cc998f81b3696f29f08a09297356f5 453 Gene3D G3DSA:1.10.10.60 386 446 2.4E-11 T 14-10-2018 Tharo_1840 d2cc998f81b3696f29f08a09297356f5 453 Pfam PF02954 Bacterial regulatory protein, Fis family 399 439 4.4E-8 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_1840 d2cc998f81b3696f29f08a09297356f5 453 Pfam PF00072 Response regulator receiver domain 12 121 4.3E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1840 d2cc998f81b3696f29f08a09297356f5 453 SMART SM00448 10 121 2.3E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1840 d2cc998f81b3696f29f08a09297356f5 453 Gene3D G3DSA:3.40.50.2300 9 141 1.4E-34 T 14-10-2018 Tharo_1840 d2cc998f81b3696f29f08a09297356f5 453 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 236 251 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Tharo_1840 d2cc998f81b3696f29f08a09297356f5 453 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 422 442 2.7E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_1840 d2cc998f81b3696f29f08a09297356f5 453 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 405 422 2.7E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_1840 d2cc998f81b3696f29f08a09297356f5 453 SMART SM00382 170 313 1.2E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1840 d2cc998f81b3696f29f08a09297356f5 453 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 174 187 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Tharo_1840 d2cc998f81b3696f29f08a09297356f5 453 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 363 372 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Tharo_1840 d2cc998f81b3696f29f08a09297356f5 453 Gene3D G3DSA:3.40.50.300 142 320 8.2E-60 T 14-10-2018 Tharo_1840 d2cc998f81b3696f29f08a09297356f5 453 Gene3D G3DSA:1.10.8.60 321 385 2.7E-17 T 14-10-2018 Tharo_1840 d2cc998f81b3696f29f08a09297356f5 453 SUPERFAMILY SSF52172 12 193 8.68E-41 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1840 d2cc998f81b3696f29f08a09297356f5 453 SUPERFAMILY SSF46689 363 441 6.72E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_1840 d2cc998f81b3696f29f08a09297356f5 453 SUPERFAMILY SSF52540 150 379 5.45E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1156 99a9cb7cae55964f7352d3f986df910b 246 SUPERFAMILY SSF51735 3 245 1.83E-78 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1156 99a9cb7cae55964f7352d3f986df910b 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 183 5.8E-5 T 14-10-2018 Tharo_1156 99a9cb7cae55964f7352d3f986df910b 246 Gene3D G3DSA:3.40.50.720 1 246 2.5E-80 T 14-10-2018 Tharo_1156 99a9cb7cae55964f7352d3f986df910b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 5.4E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1156 99a9cb7cae55964f7352d3f986df910b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 5.4E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1156 99a9cb7cae55964f7352d3f986df910b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 5.4E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1156 99a9cb7cae55964f7352d3f986df910b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 5.4E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1156 99a9cb7cae55964f7352d3f986df910b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 5.4E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1156 99a9cb7cae55964f7352d3f986df910b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 5.4E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1156 99a9cb7cae55964f7352d3f986df910b 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Tharo_1156 99a9cb7cae55964f7352d3f986df910b 246 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 3 245 5.4E-113 T 14-10-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216|MetaCyc: PWY-7948 Tharo_1156 99a9cb7cae55964f7352d3f986df910b 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 5.4E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1156 99a9cb7cae55964f7352d3f986df910b 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 5.4E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1156 99a9cb7cae55964f7352d3f986df910b 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 5.4E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1156 99a9cb7cae55964f7352d3f986df910b 246 Pfam PF00106 short chain dehydrogenase 4 195 5.1E-60 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0078 ca2510704d917f59e401f6e3f03078ec 80 Gene3D G3DSA:1.10.1220.10 5 36 4.1E-7 T 14-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 Tharo_0078 ca2510704d917f59e401f6e3f03078ec 80 SUPERFAMILY SSF47598 1 41 1.11E-10 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Tharo_2888 542a1470b6929b7a6de59d665bfe3526 660 SMART SM00382 348 521 3.5E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2888 542a1470b6929b7a6de59d665bfe3526 660 SUPERFAMILY SSF52540 341 538 3.17E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2888 542a1470b6929b7a6de59d665bfe3526 660 Pfam PF08707 Primase C terminal 2 (PriCT-2) 1 54 5.3E-11 T 14-10-2018 IPR014819 Primase, C-terminal 2 GO:0016817 Tharo_2888 542a1470b6929b7a6de59d665bfe3526 660 Gene3D G3DSA:3.40.50.300 329 557 3.9E-42 T 14-10-2018 Tharo_2888 542a1470b6929b7a6de59d665bfe3526 660 Pfam PF13481 AAA domain 320 497 7.5E-37 T 14-10-2018 Tharo_2888 542a1470b6929b7a6de59d665bfe3526 660 Pfam PF13362 Toprim domain 215 306 1.9E-7 T 14-10-2018 IPR006171 TOPRIM domain Tharo_1972 4052eba916b302642ad59339b542c283 202 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 1 200 19.374 T 14-10-2018 IPR006008 Intracellular septation protein A GO:0016021 Tharo_1972 4052eba916b302642ad59339b542c283 202 TIGRFAM TIGR00997 ispZ: intracellular septation protein A 1 201 4.2E-55 T 14-10-2018 IPR006008 Intracellular septation protein A GO:0016021 Tharo_1972 4052eba916b302642ad59339b542c283 202 Pfam PF04279 Intracellular septation protein A 1 199 3.7E-71 T 14-10-2018 IPR006008 Intracellular septation protein A GO:0016021 Tharo_1833 17f530c721b6d413d817b76b4df19a7b 388 SUPERFAMILY SSF56796 4 386 1.96E-111 T 14-10-2018 Tharo_1833 17f530c721b6d413d817b76b4df19a7b 388 Gene3D G3DSA:1.20.1090.10 187 387 7.0E-57 T 14-10-2018 Tharo_1833 17f530c721b6d413d817b76b4df19a7b 388 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 175 203 - T 14-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 Tharo_1833 17f530c721b6d413d817b76b4df19a7b 388 Pfam PF00465 Iron-containing alcohol dehydrogenase 12 380 4.5E-109 T 14-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 Tharo_1833 17f530c721b6d413d817b76b4df19a7b 388 Gene3D G3DSA:3.40.50.1970 1 186 6.8E-52 T 14-10-2018 Tharo_0398 85a1ac36afbafd292d3bd19ef75c5576 165 Gene3D G3DSA:2.30.30.40 21 146 5.4E-41 T 14-10-2018 Tharo_0398 85a1ac36afbafd292d3bd19ef75c5576 165 Gene3D G3DSA:2.40.50.180 38 147 5.4E-41 T 14-10-2018 Tharo_0398 85a1ac36afbafd292d3bd19ef75c5576 165 SUPERFAMILY SSF50341 16 156 3.4E-40 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 Tharo_0398 85a1ac36afbafd292d3bd19ef75c5576 165 SMART SM00260 15 152 1.0E-44 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Tharo_0398 85a1ac36afbafd292d3bd19ef75c5576 165 Pfam PF01584 CheW-like domain 19 154 2.8E-37 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Tharo_2514 bd2d8926d62fc1698f502e08b5eca304 136 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 117 3.3E-48 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2514 bd2d8926d62fc1698f502e08b5eca304 136 SUPERFAMILY SSF50104 1 124 8.82E-45 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily Tharo_2514 bd2d8926d62fc1698f502e08b5eca304 136 PRINTS PR00061 Ribosomal protein L19 signature 8 37 7.3E-34 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2514 bd2d8926d62fc1698f502e08b5eca304 136 PRINTS PR00061 Ribosomal protein L19 signature 38 67 7.3E-34 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2514 bd2d8926d62fc1698f502e08b5eca304 136 PRINTS PR00061 Ribosomal protein L19 signature 92 117 7.3E-34 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2514 bd2d8926d62fc1698f502e08b5eca304 136 ProSitePatterns PS01015 Ribosomal protein L19 signature. 90 105 - T 14-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2514 bd2d8926d62fc1698f502e08b5eca304 136 PIRSF PIRSF002191 1 136 3.5E-52 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2514 bd2d8926d62fc1698f502e08b5eca304 136 Gene3D G3DSA:2.30.30.790 2 121 3.4E-16 T 14-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2514 bd2d8926d62fc1698f502e08b5eca304 136 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 118 30.19 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2514 bd2d8926d62fc1698f502e08b5eca304 136 Pfam PF01245 Ribosomal protein L19 2 117 2.0E-46 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2036 a7985326c77739de02330d0f63894f39 382 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 12 380 3.3E-122 T 14-10-2018 IPR007434 Peptidogalycan biosysnthesis/recognition Tharo_2036 a7985326c77739de02330d0f63894f39 382 Gene3D G3DSA:3.40.630.30 184 331 3.5E-5 T 14-10-2018 Tharo_2036 a7985326c77739de02330d0f63894f39 382 SUPERFAMILY SSF55729 182 348 2.94E-31 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Tharo_1591 095ac4b3a6a6e11c6b6578215b06fbf8 678 SUPERFAMILY SSF52540 9 419 2.9E-133 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1591 095ac4b3a6a6e11c6b6578215b06fbf8 678 Pfam PF12344 Ultra-violet resistance protein B 556 598 2.2E-21 T 14-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain Tharo_1591 095ac4b3a6a6e11c6b6578215b06fbf8 678 Pfam PF04851 Type III restriction enzyme, res subunit 42 143 2.6E-9 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 Tharo_1591 095ac4b3a6a6e11c6b6578215b06fbf8 678 SMART SM00487 14 436 4.3E-25 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Tharo_1591 095ac4b3a6a6e11c6b6578215b06fbf8 678 Hamap MF_00204 UvrABC system protein B [uvrB]. 8 668 43.401 T 14-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 Tharo_1591 095ac4b3a6a6e11c6b6578215b06fbf8 678 SMART SM00490 464 550 4.3E-20 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_1591 095ac4b3a6a6e11c6b6578215b06fbf8 678 Gene3D G3DSA:4.10.860.10 618 673 1.6E-17 T 14-10-2018 Tharo_1591 095ac4b3a6a6e11c6b6578215b06fbf8 678 Gene3D G3DSA:3.40.50.300 4 248 1.5E-71 T 14-10-2018 Tharo_1591 095ac4b3a6a6e11c6b6578215b06fbf8 678 Pfam PF02151 UvrB/uvrC motif 635 667 1.7E-7 T 14-10-2018 IPR001943 UVR domain GO:0005515 Tharo_1591 095ac4b3a6a6e11c6b6578215b06fbf8 678 SUPERFAMILY SSF46600 622 668 6.54E-11 T 14-10-2018 IPR036876 UVR domain superfamily Tharo_1591 095ac4b3a6a6e11c6b6578215b06fbf8 678 Pfam PF00271 Helicase conserved C-terminal domain 443 548 4.9E-19 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_1591 095ac4b3a6a6e11c6b6578215b06fbf8 678 SUPERFAMILY SSF52540 42 587 5.33E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1591 095ac4b3a6a6e11c6b6578215b06fbf8 678 Gene3D G3DSA:3.40.50.300 272 418 1.0E-50 T 14-10-2018 Tharo_1591 095ac4b3a6a6e11c6b6578215b06fbf8 678 Gene3D G3DSA:3.40.50.300 419 600 1.2E-50 T 14-10-2018 Tharo_1591 095ac4b3a6a6e11c6b6578215b06fbf8 678 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 10 666 0.0 T 14-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 Tharo_1850 0e07d81cd703a80562844bdf93591523 151 SMART SM00422 1 70 2.4E-28 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Tharo_1850 0e07d81cd703a80562844bdf93591523 151 TIGRFAM TIGR02047 CadR-PbrR: Cd(II)/Pb(II)-responsive transcriptional regulator 1 127 4.6E-53 T 14-10-2018 IPR011791 Cd(II)/Pb(II)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0045893|GO:0046872 Tharo_1850 0e07d81cd703a80562844bdf93591523 151 SUPERFAMILY SSF46955 1 124 1.14E-34 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily Tharo_1850 0e07d81cd703a80562844bdf93591523 151 Pfam PF13411 MerR HTH family regulatory protein 1 68 4.8E-20 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Tharo_1850 0e07d81cd703a80562844bdf93591523 151 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.2E-9 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Tharo_1850 0e07d81cd703a80562844bdf93591523 151 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.2E-9 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Tharo_1850 0e07d81cd703a80562844bdf93591523 151 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.2E-9 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Tharo_1850 0e07d81cd703a80562844bdf93591523 151 Gene3D G3DSA:1.10.1660.10 1 125 1.3E-32 T 14-10-2018 Tharo_2326 03c23b359ca482da08cf4d9b60e4eb7b 300 Pfam PF00892 EamA-like transporter family 147 278 6.0E-7 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Tharo_2326 03c23b359ca482da08cf4d9b60e4eb7b 300 Pfam PF00892 EamA-like transporter family 7 136 2.0E-16 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Tharo_2326 03c23b359ca482da08cf4d9b60e4eb7b 300 SUPERFAMILY SSF103481 40 139 8.11E-17 T 14-10-2018 Tharo_2326 03c23b359ca482da08cf4d9b60e4eb7b 300 SUPERFAMILY SSF103481 181 282 3.53E-11 T 14-10-2018 Tharo_0789 b2acd48a11a6ac98ac256b5f5c01e2a2 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.0E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0789 b2acd48a11a6ac98ac256b5f5c01e2a2 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.0E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0789 b2acd48a11a6ac98ac256b5f5c01e2a2 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.0E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0789 b2acd48a11a6ac98ac256b5f5c01e2a2 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 64 2.9E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0789 b2acd48a11a6ac98ac256b5f5c01e2a2 313 Gene3D G3DSA:1.10.10.10 1 86 4.5E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0789 b2acd48a11a6ac98ac256b5f5c01e2a2 313 Gene3D G3DSA:3.40.190.10 93 303 1.1E-94 T 14-10-2018 Tharo_0789 b2acd48a11a6ac98ac256b5f5c01e2a2 313 SUPERFAMILY SSF53850 91 300 3.5E-39 T 14-10-2018 Tharo_0789 b2acd48a11a6ac98ac256b5f5c01e2a2 313 Pfam PF03466 LysR substrate binding domain 90 290 9.8E-41 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_0789 b2acd48a11a6ac98ac256b5f5c01e2a2 313 Gene3D G3DSA:3.40.190.10 167 267 1.1E-94 T 14-10-2018 Tharo_0789 b2acd48a11a6ac98ac256b5f5c01e2a2 313 SUPERFAMILY SSF46785 1 112 9.31E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_3352 e8c6ce67f9440d615b1e52fc239db1bc 216 SUPERFAMILY SSF48452 61 183 2.66E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_3352 e8c6ce67f9440d615b1e52fc239db1bc 216 Gene3D G3DSA:1.25.40.10 24 215 3.0E-17 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_0841 6457042cd99873494109fd6e2a9392ee 259 PIRSF PIRSF000094 4 259 1.9E-83 T 14-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Tharo_0841 6457042cd99873494109fd6e2a9392ee 259 Gene3D G3DSA:3.40.50.720 3 259 4.2E-58 T 14-10-2018 Tharo_0841 6457042cd99873494109fd6e2a9392ee 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 7.0E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0841 6457042cd99873494109fd6e2a9392ee 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 7.0E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0841 6457042cd99873494109fd6e2a9392ee 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 7.0E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0841 6457042cd99873494109fd6e2a9392ee 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 7.0E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0841 6457042cd99873494109fd6e2a9392ee 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 7.0E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0841 6457042cd99873494109fd6e2a9392ee 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 256 1.2E-77 T 14-10-2018 Tharo_0841 6457042cd99873494109fd6e2a9392ee 259 SUPERFAMILY SSF51735 8 258 1.88E-65 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_0079 7d5c07b1c35e7b1eff9e290cf760afc6 169 Gene3D G3DSA:2.60.40.1820 38 160 1.3E-11 T 14-10-2018 Tharo_0079 7d5c07b1c35e7b1eff9e290cf760afc6 169 SUPERFAMILY SSF117070 16 159 3.01E-30 T 14-10-2018 Tharo_0079 7d5c07b1c35e7b1eff9e290cf760afc6 169 SMART SM00769 38 158 3.8E-39 T 14-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 Tharo_0079 7d5c07b1c35e7b1eff9e290cf760afc6 169 Pfam PF03168 Late embryogenesis abundant protein 58 143 1.8E-20 T 14-10-2018 IPR004864 Late embryogenesis abundant protein, LEA_2 subgroup Tharo_2568 c1535bca4b09404448147e0cd53afe38 329 PIRSF PIRSF015753 5 323 2.8E-129 T 14-10-2018 IPR016639 Glutathione S-transferase Omega/GSH GO:0004364 Tharo_2568 c1535bca4b09404448147e0cd53afe38 329 Gene3D G3DSA:1.20.1050.10 173 283 1.0E-131 T 14-10-2018 Tharo_2568 c1535bca4b09404448147e0cd53afe38 329 SUPERFAMILY SSF52833 40 162 3.08E-16 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_2568 c1535bca4b09404448147e0cd53afe38 329 SUPERFAMILY SSF47616 176 323 7.94E-36 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily Tharo_2568 c1535bca4b09404448147e0cd53afe38 329 Gene3D G3DSA:3.40.30.130 21 316 1.0E-131 T 14-10-2018 Tharo_2568 c1535bca4b09404448147e0cd53afe38 329 Pfam PF13409 Glutathione S-transferase, N-terminal domain 62 157 4.1E-22 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 Tharo_2568 c1535bca4b09404448147e0cd53afe38 329 Pfam PF13410 Glutathione S-transferase, C-terminal domain 203 271 4.5E-13 T 14-10-2018 Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 Pfam PF00679 Elongation factor G C-terminus 399 484 9.8E-22 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 Pfam PF06421 GTP-binding protein LepA C-terminus 488 593 7.4E-50 T 14-10-2018 IPR013842 GTP-binding protein LepA, C-terminal Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 Gene3D G3DSA:3.30.70.2570 479 553 3.2E-32 T 14-10-2018 IPR038363 LepA, C-terminal domain superfamily Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 174 4.5E-16 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 SUPERFAMILY SSF52540 2 205 2.87E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 SUPERFAMILY SSF54980 292 370 1.83E-18 T 14-10-2018 IPR035647 EF-G domain III/V-like Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 Gene3D G3DSA:3.30.70.870 286 367 4.3E-36 T 14-10-2018 Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 SUPERFAMILY SSF50447 165 288 7.28E-29 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 Gene3D G3DSA:3.40.50.300 1 185 1.8E-71 T 14-10-2018 Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 Gene3D G3DSA:2.40.30.10 186 285 3.6E-33 T 14-10-2018 Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 Pfam PF00009 Elongation factor Tu GTP binding domain 3 181 4.7E-52 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 Hamap MF_00071 Elongation factor 4 [lepA]. 1 597 307.773 T 14-10-2018 IPR006297 Elongation factor 4 GO:0005525 Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 SUPERFAMILY SSF54980 399 493 9.59E-25 T 14-10-2018 IPR035647 EF-G domain III/V-like Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 Gene3D G3DSA:3.30.70.3380 368 478 8.6E-42 T 14-10-2018 Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 TIGRFAM TIGR01393 lepA: elongation factor 4 3 595 3.1E-301 T 14-10-2018 IPR006297 Elongation factor 4 GO:0005525 Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 Pfam PF03144 Elongation factor Tu domain 2 205 275 7.3E-9 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 PRINTS PR00315 GTP-binding elongation factor signature 90 101 3.1E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 PRINTS PR00315 GTP-binding elongation factor signature 126 135 3.1E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 PRINTS PR00315 GTP-binding elongation factor signature 6 19 3.1E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 PRINTS PR00315 GTP-binding elongation factor signature 74 84 3.1E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_1614 6e80a8a392111c6ee84163805ea19bd9 598 PRINTS PR00315 GTP-binding elongation factor signature 49 57 3.1E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2757 8aebda92b21ca28971750bcb4dc7fa7b 573 Pfam PF00263 Bacterial type II and III secretion system protein 349 515 4.2E-43 T 14-10-2018 IPR004846 Type II/III secretion system GO:0009306 Tharo_2757 8aebda92b21ca28971750bcb4dc7fa7b 573 PRINTS PR00811 Bacterial general secretion pathway protein D signature 345 369 2.9E-13 T 14-10-2018 IPR001775 GspD/PilQ family Tharo_2757 8aebda92b21ca28971750bcb4dc7fa7b 573 PRINTS PR00811 Bacterial general secretion pathway protein D signature 502 516 2.9E-13 T 14-10-2018 IPR001775 GspD/PilQ family Tharo_2757 8aebda92b21ca28971750bcb4dc7fa7b 573 PRINTS PR00811 Bacterial general secretion pathway protein D signature 242 252 2.9E-13 T 14-10-2018 IPR001775 GspD/PilQ family Tharo_2757 8aebda92b21ca28971750bcb4dc7fa7b 573 PRINTS PR00811 Bacterial general secretion pathway protein D signature 479 497 2.9E-13 T 14-10-2018 IPR001775 GspD/PilQ family Tharo_2757 8aebda92b21ca28971750bcb4dc7fa7b 573 Pfam PF13629 Pilus formation protein N terminal region 124 167 1.6E-8 T 14-10-2018 IPR032789 Pilus formation protein, N-terminal Tharo_0481 169d20e1b723e22e0f2dbe6e105dc4a7 163 Pfam PF03652 Holliday junction resolvase 24 156 7.1E-38 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 Tharo_0481 169d20e1b723e22e0f2dbe6e105dc4a7 163 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 23 159 23.301 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 Tharo_0481 169d20e1b723e22e0f2dbe6e105dc4a7 163 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 26 156 1.3E-34 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 Tharo_0481 169d20e1b723e22e0f2dbe6e105dc4a7 163 SUPERFAMILY SSF53098 23 157 1.14E-35 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_0481 169d20e1b723e22e0f2dbe6e105dc4a7 163 SMART SM00732 23 123 6.8E-26 T 14-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 Tharo_0481 169d20e1b723e22e0f2dbe6e105dc4a7 163 Gene3D G3DSA:3.30.420.140 21 158 2.0E-39 T 14-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 Tharo_2571 85ea9de37d33d5e38f250b22a7c1ed3e 130 Pfam PF16363 GDP-mannose 4,6 dehydratase 2 102 2.7E-20 T 14-10-2018 IPR016040 NAD(P)-binding domain Tharo_2571 85ea9de37d33d5e38f250b22a7c1ed3e 130 Gene3D G3DSA:3.90.25.10 1 109 5.3E-31 T 14-10-2018 Tharo_2571 85ea9de37d33d5e38f250b22a7c1ed3e 130 Gene3D G3DSA:3.40.50.720 7 101 5.3E-31 T 14-10-2018 Tharo_2571 85ea9de37d33d5e38f250b22a7c1ed3e 130 SUPERFAMILY SSF51735 1 125 2.68E-24 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_0039 217ba6e03ddbc66d87100640a2ab37ee 446 Gene3D G3DSA:3.40.50.80 323 446 8.1E-19 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_0039 217ba6e03ddbc66d87100640a2ab37ee 446 SUPERFAMILY SSF52343 324 444 1.96E-20 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_0039 217ba6e03ddbc66d87100640a2ab37ee 446 Gene3D G3DSA:2.40.30.10 215 313 8.9E-11 T 14-10-2018 Tharo_0039 217ba6e03ddbc66d87100640a2ab37ee 446 Pfam PF00970 Oxidoreductase FAD-binding domain 234 316 1.1E-4 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 Tharo_0039 217ba6e03ddbc66d87100640a2ab37ee 446 SUPERFAMILY SSF63380 235 315 3.76E-14 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Tharo_0039 217ba6e03ddbc66d87100640a2ab37ee 446 Pfam PF01794 Ferric reductase like transmembrane component 43 177 5.7E-17 T 14-10-2018 IPR013130 Ferric reductase transmembrane component-like domain Tharo_0437 68b23d6b229db56e320a0dd514dda538 241 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 237 2.8E-92 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0437 68b23d6b229db56e320a0dd514dda538 241 Gene3D G3DSA:1.10.10.200 1 80 3.7E-35 T 14-10-2018 IPR017856 Integrase-like, N-terminal Tharo_0437 68b23d6b229db56e320a0dd514dda538 241 Gene3D G3DSA:3.30.70.980 86 235 9.2E-51 T 14-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0437 68b23d6b229db56e320a0dd514dda538 241 Pfam PF01709 Transcriptional regulator 5 236 9.3E-93 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0437 68b23d6b229db56e320a0dd514dda538 241 Gene3D G3DSA:3.30.70.980 130 205 9.2E-51 T 14-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0437 68b23d6b229db56e320a0dd514dda538 241 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 35.635 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0437 68b23d6b229db56e320a0dd514dda538 241 SUPERFAMILY SSF75625 3 239 9.03E-96 T 14-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_1355 26457f49920abc1bf7c0b24146abf388 89 SUPERFAMILY SSF47060 3 89 1.85E-34 T 14-10-2018 IPR009068 S15/NS1, RNA-binding Tharo_1355 26457f49920abc1bf7c0b24146abf388 89 Gene3D G3DSA:1.10.287.10 2 89 1.5E-35 T 14-10-2018 Tharo_1355 26457f49920abc1bf7c0b24146abf388 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 2.0E-37 T 14-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1355 26457f49920abc1bf7c0b24146abf388 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 21.659 T 14-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1355 26457f49920abc1bf7c0b24146abf388 89 Pfam PF00312 Ribosomal protein S15 8 88 3.5E-37 T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_1355 26457f49920abc1bf7c0b24146abf388 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 1.0E-35 T 14-10-2018 Tharo_1355 26457f49920abc1bf7c0b24146abf388 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_1355 26457f49920abc1bf7c0b24146abf388 89 SMART SM01387 8 88 1.1E-50 T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_0686 ac008bd46e957487bc42d0b1374765d6 628 Pfam PF07515 Putative conjugal transfer nickase/helicase TraI C-term 501 623 2.3E-46 T 14-10-2018 IPR011093 Putative conjugal transfer nickase/helicase TraI, C-terminal Tharo_0686 ac008bd46e957487bc42d0b1374765d6 628 Gene3D G3DSA:1.10.10.10 502 572 1.3E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0686 ac008bd46e957487bc42d0b1374765d6 628 Gene3D G3DSA:2.40.10.200 518 619 1.3E-24 T 14-10-2018 Tharo_0686 ac008bd46e957487bc42d0b1374765d6 628 Pfam PF07514 Putative helicase 36 348 3.7E-130 T 14-10-2018 IPR011119 Uncharacterised domain, helicase/relaxase, putative Tharo_0686 ac008bd46e957487bc42d0b1374765d6 628 SUPERFAMILY SSF46785 499 623 1.17E-41 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0686 ac008bd46e957487bc42d0b1374765d6 628 Gene3D G3DSA:1.10.3210.40 37 258 2.0E-41 T 14-10-2018 Tharo_0686 ac008bd46e957487bc42d0b1374765d6 628 TIGRFAM TIGR03760 ICE_TraI_Pfluor: integrating conjugative element relaxase, PFGI-1 class 34 251 2.5E-89 T 14-10-2018 IPR022391 Integrating conjugative element relaxase, PFGI-1 class Tharo_1085 d809ca13a1574449ae03b31ece1ca9b5 147 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 3 115 4.3E-28 T 14-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 Tharo_1085 d809ca13a1574449ae03b31ece1ca9b5 147 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 2 144 7.3E-36 T 14-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 Tharo_1085 d809ca13a1574449ae03b31ece1ca9b5 147 PIRSF PIRSF006113 93 146 4.4 T 14-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 Tharo_1085 d809ca13a1574449ae03b31ece1ca9b5 147 PIRSF PIRSF006113 1 82 2.3E-18 T 14-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 Tharo_1085 d809ca13a1574449ae03b31ece1ca9b5 147 SUPERFAMILY SSF55620 1 145 5.56E-39 T 14-10-2018 Tharo_1085 d809ca13a1574449ae03b31ece1ca9b5 147 Gene3D G3DSA:3.30.479.10 91 147 6.4E-10 T 14-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 Tharo_1085 d809ca13a1574449ae03b31ece1ca9b5 147 Gene3D G3DSA:3.30.479.10 1 90 1.4E-23 T 14-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 Tharo_2459 aa491195d75452627425708b36f12751 424 SUPERFAMILY SSF81901 277 419 1.4E-15 T 14-10-2018 Tharo_2459 aa491195d75452627425708b36f12751 424 Gene3D G3DSA:1.10.510.10 2 252 7.0E-29 T 14-10-2018 Tharo_2459 aa491195d75452627425708b36f12751 424 SMART SM00220 7 253 1.0E-10 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Tharo_2459 aa491195d75452627425708b36f12751 424 Pfam PF00069 Protein kinase domain 10 244 1.6E-20 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Tharo_2459 aa491195d75452627425708b36f12751 424 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 13 36 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 Tharo_2459 aa491195d75452627425708b36f12751 424 SUPERFAMILY SSF56112 4 244 1.35E-35 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Tharo_2459 aa491195d75452627425708b36f12751 424 Gene3D G3DSA:1.25.40.10 264 422 2.2E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_2459 aa491195d75452627425708b36f12751 424 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 123 135 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Tharo_2286 33657fc7405b7a77acd0ba21e3d2bdec 463 SMART SM00729 57 278 4.4E-47 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Tharo_2286 33657fc7405b7a77acd0ba21e3d2bdec 463 Gene3D G3DSA:1.10.10.920 370 463 6.5E-33 T 14-10-2018 Tharo_2286 33657fc7405b7a77acd0ba21e3d2bdec 463 Pfam PF06969 HemN C-terminal domain 369 437 6.3E-9 T 14-10-2018 IPR010723 HemN, C-terminal Tharo_2286 33657fc7405b7a77acd0ba21e3d2bdec 463 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 9 463 4.0E-182 T 14-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 Tharo_2286 33657fc7405b7a77acd0ba21e3d2bdec 463 Pfam PF04055 Radical SAM superfamily 63 233 1.8E-19 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_2286 33657fc7405b7a77acd0ba21e3d2bdec 463 PIRSF PIRSF000167 7 460 3.9E-163 T 14-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 Tharo_2286 33657fc7405b7a77acd0ba21e3d2bdec 463 SUPERFAMILY SSF102114 9 450 5.23E-138 T 14-10-2018 Tharo_2286 33657fc7405b7a77acd0ba21e3d2bdec 463 Gene3D G3DSA:3.80.30.20 3 369 6.1E-124 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Tharo_1139 f9783bb4ad29e0a517f36c453b4aaeef 315 Pfam PF12762 ISXO2-like transposase domain 136 281 1.1E-29 T 14-10-2018 IPR024445 ISXO2-like transposase domain Tharo_1139 f9783bb4ad29e0a517f36c453b4aaeef 315 SMART SM01126 135 281 3.8E-39 T 14-10-2018 IPR024445 ISXO2-like transposase domain Tharo_1139 f9783bb4ad29e0a517f36c453b4aaeef 315 Pfam PF12760 Transposase zinc-ribbon domain 21 67 3.4E-13 T 14-10-2018 IPR024442 Transposase, zinc-ribbon Tharo_0202 ee816c49e5161ba9d7956b108addfacc 374 Pfam PF13808 DDE_Tnp_1-associated 3 89 1.2E-29 T 14-10-2018 IPR032806 H repeat-associated protein, N-terminal Tharo_0202 ee816c49e5161ba9d7956b108addfacc 374 Pfam PF01609 Transposase DDE domain 98 333 2.8E-19 T 14-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 Tharo_1109 fa731b37037df37fcd18d6ecc38c0575 441 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 13 431 5.1E-84 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit Tharo_1109 fa731b37037df37fcd18d6ecc38c0575 441 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 22 435 1.6E-87 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 Tharo_1109 fa731b37037df37fcd18d6ecc38c0575 441 PIRSF PIRSF006066 5 441 1.4E-85 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 Tharo_3355 7c2abe258b6095aeea68d92dc99f924c 502 Pfam PF00501 AMP-binding enzyme 9 386 5.1E-52 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Tharo_3355 7c2abe258b6095aeea68d92dc99f924c 502 Gene3D G3DSA:3.30.300.30 383 490 9.8E-7 T 14-10-2018 Tharo_3355 7c2abe258b6095aeea68d92dc99f924c 502 SUPERFAMILY SSF56801 4 493 7.33E-82 T 14-10-2018 Tharo_3355 7c2abe258b6095aeea68d92dc99f924c 502 Gene3D G3DSA:3.40.50.12780 5 379 1.8E-61 T 14-10-2018 Tharo_3355 7c2abe258b6095aeea68d92dc99f924c 502 ProSitePatterns PS00455 Putative AMP-binding domain signature. 138 149 - T 14-10-2018 IPR020845 AMP-binding, conserved site Tharo_2954 87daa0973d0934cd54114599765b0761 210 SUPERFAMILY SSF52833 21 187 3.84E-33 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_2954 87daa0973d0934cd54114599765b0761 210 Gene3D G3DSA:3.40.30.10 24 210 1.3E-45 T 14-10-2018 Tharo_2954 87daa0973d0934cd54114599765b0761 210 ProSitePatterns PS00194 Thioredoxin family active site. 45 63 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 Tharo_2954 87daa0973d0934cd54114599765b0761 210 PIRSF PIRSF001488 6 207 9.0E-39 T 14-10-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL Tharo_2954 87daa0973d0934cd54114599765b0761 210 Pfam PF01323 DSBA-like thioredoxin domain 81 180 4.1E-12 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 Tharo_1623 b9f61ca3b2f7fedb88749180bc7ccf91 606 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 384 539 3.6E-50 T 14-10-2018 IPR001162 UvrC family homology region Tharo_1623 b9f61ca3b2f7fedb88749180bc7ccf91 606 Gene3D G3DSA:3.40.1440.10 13 108 1.5E-31 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 Tharo_1623 b9f61ca3b2f7fedb88749180bc7ccf91 606 Pfam PF14520 Helix-hairpin-helix domain 554 606 2.5E-9 T 14-10-2018 Tharo_1623 b9f61ca3b2f7fedb88749180bc7ccf91 606 SUPERFAMILY SSF47781 503 606 1.94E-21 T 14-10-2018 IPR010994 RuvA domain 2-like Tharo_1623 b9f61ca3b2f7fedb88749180bc7ccf91 606 SUPERFAMILY SSF82771 24 106 1.15E-22 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 Tharo_1623 b9f61ca3b2f7fedb88749180bc7ccf91 606 SMART SM00465 23 104 1.2E-19 T 14-10-2018 IPR000305 GIY-YIG endonuclease Tharo_1623 b9f61ca3b2f7fedb88749180bc7ccf91 606 Hamap MF_00203 UvrABC system protein C [uvrC]. 10 604 27.155 T 14-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 Tharo_1623 b9f61ca3b2f7fedb88749180bc7ccf91 606 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 17 586 1.1E-172 T 14-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 Tharo_1623 b9f61ca3b2f7fedb88749180bc7ccf91 606 SMART SM00278 585 604 0.097 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Tharo_1623 b9f61ca3b2f7fedb88749180bc7ccf91 606 SMART SM00278 553 572 0.41 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Tharo_1623 b9f61ca3b2f7fedb88749180bc7ccf91 606 Gene3D G3DSA:1.10.150.20 552 606 3.6E-21 T 14-10-2018 Tharo_1623 b9f61ca3b2f7fedb88749180bc7ccf91 606 Pfam PF01541 GIY-YIG catalytic domain 24 99 1.7E-9 T 14-10-2018 IPR000305 GIY-YIG endonuclease Tharo_1623 b9f61ca3b2f7fedb88749180bc7ccf91 606 Pfam PF02151 UvrB/uvrC motif 210 243 8.4E-9 T 14-10-2018 IPR001943 UVR domain GO:0005515 Tharo_1623 b9f61ca3b2f7fedb88749180bc7ccf91 606 SUPERFAMILY SSF46600 197 248 5.75E-12 T 14-10-2018 IPR036876 UVR domain superfamily Tharo_1623 b9f61ca3b2f7fedb88749180bc7ccf91 606 Gene3D G3DSA:3.30.420.340 376 549 4.3E-50 T 14-10-2018 IPR038476 UvrC homology region 2 superfamily Tharo_0994 8eb176bbd8c7a82f0564c9cef91d7b0c 380 SMART SM00564 317 348 0.15 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Tharo_0994 8eb176bbd8c7a82f0564c9cef91d7b0c 380 SMART SM00564 276 307 200.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Tharo_0994 8eb176bbd8c7a82f0564c9cef91d7b0c 380 SMART SM00564 101 133 10.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Tharo_0994 8eb176bbd8c7a82f0564c9cef91d7b0c 380 SMART SM00564 142 173 0.074 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Tharo_0994 8eb176bbd8c7a82f0564c9cef91d7b0c 380 SMART SM00564 187 218 880.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Tharo_0994 8eb176bbd8c7a82f0564c9cef91d7b0c 380 SMART SM00564 64 93 130.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Tharo_0994 8eb176bbd8c7a82f0564c9cef91d7b0c 380 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 3 379 34.843 T 14-10-2018 IPR017687 Outer membrane protein assembly factor BamB Tharo_0994 8eb176bbd8c7a82f0564c9cef91d7b0c 380 SUPERFAMILY SSF50998 25 369 1.88E-70 T 14-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily Tharo_0994 8eb176bbd8c7a82f0564c9cef91d7b0c 380 Gene3D G3DSA:2.130.10.10 26 380 2.2E-84 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Tharo_0994 8eb176bbd8c7a82f0564c9cef91d7b0c 380 Pfam PF13360 PQQ-like domain 78 306 3.2E-52 T 14-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat Tharo_0994 8eb176bbd8c7a82f0564c9cef91d7b0c 380 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 7 377 1.2E-123 T 14-10-2018 IPR017687 Outer membrane protein assembly factor BamB Tharo_3070 014b2030fbe1c33277510ae40a650160 861 SUPERFAMILY SSF51998 58 848 3.07E-186 T 14-10-2018 Tharo_3070 014b2030fbe1c33277510ae40a650160 861 Pfam PF01228 Glycine radical 732 831 4.1E-21 T 14-10-2018 IPR001150 Glycine radical domain GO:0003824 Tharo_3070 014b2030fbe1c33277510ae40a650160 861 Gene3D G3DSA:3.20.70.40 53 849 5.8E-226 T 14-10-2018 Tharo_3070 014b2030fbe1c33277510ae40a650160 861 Pfam PF02901 Pyruvate formate lyase-like 40 712 5.1E-185 T 14-10-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 Tharo_1742 2df23b1612f9697be73da6a8de9c1b02 298 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 51 261 6.2E-50 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Tharo_1742 2df23b1612f9697be73da6a8de9c1b02 298 Gene3D G3DSA:3.40.1010.10 49 165 1.1E-45 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Tharo_1742 2df23b1612f9697be73da6a8de9c1b02 298 Gene3D G3DSA:3.30.950.10 166 294 6.8E-43 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 Tharo_1742 2df23b1612f9697be73da6a8de9c1b02 298 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 55 69 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Tharo_1742 2df23b1612f9697be73da6a8de9c1b02 298 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 130 163 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Tharo_1742 2df23b1612f9697be73da6a8de9c1b02 298 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 50 285 7.6E-93 T 14-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Tharo_1742 2df23b1612f9697be73da6a8de9c1b02 298 SUPERFAMILY SSF53790 49 284 8.51E-77 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Tharo_3192 ca4284543c4b61e8ecc87d24c1642614 156 SUPERFAMILY SSF75217 2 153 3.19E-42 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases Tharo_3192 ca4284543c4b61e8ecc87d24c1642614 156 PIRSF PIRSF004505 1 155 2.8E-37 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 Tharo_3192 ca4284543c4b61e8ecc87d24c1642614 156 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 155 25.825 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 Tharo_3192 ca4284543c4b61e8ecc87d24c1642614 156 Pfam PF02590 Predicted SPOUT methyltransferase 2 154 8.1E-42 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 Tharo_3192 ca4284543c4b61e8ecc87d24c1642614 156 Gene3D G3DSA:3.40.1280.10 1 156 4.6E-44 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Tharo_0460 8576885efb1a4b20e37c2872b408a57b 220 Gene3D G3DSA:3.90.550.10 21 214 3.8E-52 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_0460 8576885efb1a4b20e37c2872b408a57b 220 SUPERFAMILY SSF53448 24 207 4.17E-32 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_0460 8576885efb1a4b20e37c2872b408a57b 220 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 23 210 27.129 T 14-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 Tharo_0460 8576885efb1a4b20e37c2872b408a57b 220 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 25 208 4.5E-69 T 14-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 Tharo_0460 8576885efb1a4b20e37c2872b408a57b 220 Pfam PF12804 MobA-like NTP transferase domain 27 179 3.6E-33 T 14-10-2018 IPR025877 MobA-like NTP transferase Tharo_0807 20d5d8c1242c7e7b0fb731ff8ac52f58 141 Pfam PF13470 PIN domain 5 114 8.8E-21 T 14-10-2018 IPR002716 PIN domain Tharo_0807 20d5d8c1242c7e7b0fb731ff8ac52f58 141 SUPERFAMILY SSF88723 1 120 1.72E-13 T 14-10-2018 IPR029060 PIN-like domain superfamily Tharo_0807 20d5d8c1242c7e7b0fb731ff8ac52f58 141 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 5 117 1.2E-16 T 14-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component Tharo_1716 76481161f4310e03354f11668b367a4e 140 Gene3D G3DSA:3.10.580.10 2 138 1.4E-32 T 14-10-2018 Tharo_1716 76481161f4310e03354f11668b367a4e 140 SUPERFAMILY SSF54631 13 127 2.65E-27 T 14-10-2018 Tharo_1716 76481161f4310e03354f11668b367a4e 140 SMART SM00116 79 126 9.1E-7 T 14-10-2018 IPR000644 CBS domain Tharo_1716 76481161f4310e03354f11668b367a4e 140 SMART SM00116 14 62 5.2E-5 T 14-10-2018 IPR000644 CBS domain Tharo_1716 76481161f4310e03354f11668b367a4e 140 Pfam PF00571 CBS domain 14 61 5.3E-4 T 14-10-2018 IPR000644 CBS domain Tharo_1716 76481161f4310e03354f11668b367a4e 140 Pfam PF00571 CBS domain 74 121 4.1E-9 T 14-10-2018 IPR000644 CBS domain Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 Pfam PF08448 PAS fold 360 467 7.6E-11 T 14-10-2018 IPR013656 PAS fold-4 Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 SMART SM00387 597 705 9.2E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 SMART SM00091 223 289 2.2E-5 T 14-10-2018 IPR000014 PAS domain Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 SMART SM00091 352 418 7.1E-8 T 14-10-2018 IPR000014 PAS domain Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 SMART SM00989 118 180 1.8E-18 T 14-10-2018 IPR004096 4-vinyl reductase, 4VR Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 Pfam PF00989 PAS fold 224 333 3.6E-8 T 14-10-2018 IPR013767 PAS fold GO:0006355 Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 PRINTS PR00344 Bacterial sensor protein C-terminal signature 665 683 1.3E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 PRINTS PR00344 Bacterial sensor protein C-terminal signature 689 702 1.3E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 PRINTS PR00344 Bacterial sensor protein C-terminal signature 634 648 1.3E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 PRINTS PR00344 Bacterial sensor protein C-terminal signature 652 662 1.3E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 355 472 1.1E-13 T 14-10-2018 IPR000014 PAS domain Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 219 343 3.2E-13 T 14-10-2018 IPR000014 PAS domain Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 SMART SM00388 480 555 2.5E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 SUPERFAMILY SSF55874 544 703 3.8E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 Gene3D G3DSA:3.30.565.10 557 708 7.5E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 SUPERFAMILY SSF47384 465 553 4.9E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 SUPERFAMILY SSF111126 44 176 4.45E-11 T 14-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 Gene3D G3DSA:3.30.450.20 343 468 2.4E-19 T 14-10-2018 Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 Gene3D G3DSA:3.30.450.20 210 342 8.6E-17 T 14-10-2018 Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 601 702 9.5E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 Pfam PF06505 Activator of aromatic catabolism 7 107 2.0E-29 T 14-10-2018 IPR010523 Activator of aromatic catabolism Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 Gene3D G3DSA:3.30.1380.20 27 183 2.7E-7 T 14-10-2018 Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 SUPERFAMILY SSF55785 363 474 4.05E-20 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 SUPERFAMILY SSF55785 213 334 9.42E-17 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 ProDom PD485437 REGULATOR TRANSCRIPTIONAL FIS-TYPE HELIX-TURN-HELIX ACTIVATOR PLASMID FAMILY PHENOL-DEGRADATIVE FIS SIGMA-54 1 135 5.0E-52 T 14-10-2018 IPR010523 Activator of aromatic catabolism Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 SMART SM00086 424 465 0.026 T 14-10-2018 IPR001610 PAC motif Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 SMART SM00086 295 336 0.39 T 14-10-2018 IPR001610 PAC motif Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 Gene3D G3DSA:1.10.287.130 469 554 2.5E-21 T 14-10-2018 Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 Pfam PF02830 V4R domain 119 174 5.0E-13 T 14-10-2018 IPR004096 4-vinyl reductase, 4VR Tharo_2903 d7085900045621ae1b332619fd8fee3e 715 Pfam PF00512 His Kinase A (phospho-acceptor) domain 480 554 4.1E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_2277 db1b4510606f4c674f2cc7003a8c5440 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 204 7.9E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2277 db1b4510606f4c674f2cc7003a8c5440 217 SUPERFAMILY SSF52172 3 135 5.55E-33 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_2277 db1b4510606f4c674f2cc7003a8c5440 217 SUPERFAMILY SSF46894 140 213 1.8E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_2277 db1b4510606f4c674f2cc7003a8c5440 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 6.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2277 db1b4510606f4c674f2cc7003a8c5440 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 6.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2277 db1b4510606f4c674f2cc7003a8c5440 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 6.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2277 db1b4510606f4c674f2cc7003a8c5440 217 Pfam PF00072 Response regulator receiver domain 6 116 1.8E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2277 db1b4510606f4c674f2cc7003a8c5440 217 SMART SM00421 150 207 3.3E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2277 db1b4510606f4c674f2cc7003a8c5440 217 SMART SM00448 4 117 2.5E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2277 db1b4510606f4c674f2cc7003a8c5440 217 Gene3D G3DSA:3.40.50.12740 4 213 1.6E-61 T 14-10-2018 Tharo_3404 912da7b1d9562dc523df74de3ad38853 44 Pfam PF00468 Ribosomal protein L34 1 44 5.0E-23 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_3404 912da7b1d9562dc523df74de3ad38853 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 1.4E-24 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_3404 912da7b1d9562dc523df74de3ad38853 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 24 1.0E-6 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_3404 912da7b1d9562dc523df74de3ad38853 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 14-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_3404 912da7b1d9562dc523df74de3ad38853 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.139 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1398 d1ed6f9b15a47258c4ec81cb84fc891a 930 Gene3D G3DSA:3.40.50.300 731 915 1.8E-13 T 14-10-2018 Tharo_1398 d1ed6f9b15a47258c4ec81cb84fc891a 930 Pfam PF13555 P-loop containing region of AAA domain 5 48 1.0E-8 T 14-10-2018 Tharo_1398 d1ed6f9b15a47258c4ec81cb84fc891a 930 SUPERFAMILY SSF52540 1 907 4.72E-25 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1398 d1ed6f9b15a47258c4ec81cb84fc891a 930 Gene3D G3DSA:3.40.50.300 2 405 9.5E-19 T 14-10-2018 Tharo_0168 627a80c4018b2a0b5e9f779f9b41464f 303 PIRSF PIRSF000105 1 303 1.7E-81 T 14-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 Tharo_0168 627a80c4018b2a0b5e9f779f9b41464f 303 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 181 278 8.1E-20 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 Tharo_0168 627a80c4018b2a0b5e9f779f9b41464f 303 SUPERFAMILY SSF48179 180 287 4.93E-21 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Tharo_0168 627a80c4018b2a0b5e9f779f9b41464f 303 SUPERFAMILY SSF51735 6 177 5.55E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_0168 627a80c4018b2a0b5e9f779f9b41464f 303 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 178 8.3E-51 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 Tharo_0168 627a80c4018b2a0b5e9f779f9b41464f 303 Gene3D G3DSA:3.40.50.720 2 181 5.4E-56 T 14-10-2018 Tharo_0168 627a80c4018b2a0b5e9f779f9b41464f 303 Gene3D G3DSA:1.10.1040.10 183 302 4.5E-35 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Tharo_2415 d5fed37bfee4f7d3a732440e6a53a80d 497 Pfam PF04966 Carbohydrate-selective porin, OprB family 236 495 3.9E-22 T 14-10-2018 IPR007049 Carbohydrate-selective porin OprB GO:0008643|GO:0015288|GO:0016021 Tharo_2415 d5fed37bfee4f7d3a732440e6a53a80d 497 Gene3D G3DSA:2.40.160.180 172 497 2.7E-29 T 14-10-2018 IPR038673 Carbohydrate-selective porin OprB superfamily Tharo_0138 5f127749b115eaa5cad5fcd6e2c1d73e 173 Pfam PF04093 rod shape-determining protein MreD 9 157 2.5E-15 T 14-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 Tharo_0138 5f127749b115eaa5cad5fcd6e2c1d73e 173 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 15 158 7.6E-32 T 14-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 Tharo_0138 5f127749b115eaa5cad5fcd6e2c1d73e 173 PIRSF PIRSF018472 7 167 3.0E-43 T 14-10-2018 IPR026034 Cell shape-determining protein MreD, proteobacterial type Tharo_2435 e3c9b69ca31a7feb4002b6a2592aa09f 1182 SUPERFAMILY SSF52980 847 1159 6.43E-53 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Tharo_2435 e3c9b69ca31a7feb4002b6a2592aa09f 1182 Gene3D G3DSA:3.40.50.300 379 820 6.8E-170 T 14-10-2018 Tharo_2435 e3c9b69ca31a7feb4002b6a2592aa09f 1182 PIRSF PIRSF000980 9 1164 2.8E-303 T 14-10-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 Tharo_2435 e3c9b69ca31a7feb4002b6a2592aa09f 1182 SUPERFAMILY SSF52540 375 826 4.78E-89 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2435 e3c9b69ca31a7feb4002b6a2592aa09f 1182 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 10 820 1.4E-255 T 14-10-2018 Tharo_2435 e3c9b69ca31a7feb4002b6a2592aa09f 1182 Gene3D G3DSA:1.10.10.160 88 206 2.4E-100 T 14-10-2018 IPR013986 DExx box DNA helicase domain superfamily Tharo_2435 e3c9b69ca31a7feb4002b6a2592aa09f 1182 Gene3D G3DSA:3.40.50.10930 13 328 2.4E-100 T 14-10-2018 Tharo_2435 e3c9b69ca31a7feb4002b6a2592aa09f 1182 TIGRFAM TIGR01450 recC: exodeoxyribonuclease V, gamma subunit 12 1123 8.6E-291 T 14-10-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 Tharo_2435 e3c9b69ca31a7feb4002b6a2592aa09f 1182 SUPERFAMILY SSF52540 10 370 6.37E-89 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2435 e3c9b69ca31a7feb4002b6a2592aa09f 1182 Hamap MF_01486 RecBCD enzyme subunit RecC [recC]. 9 1163 19.129 T 14-10-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 Tharo_2435 e3c9b69ca31a7feb4002b6a2592aa09f 1182 Gene3D G3DSA:1.10.486.10 460 674 6.8E-170 T 14-10-2018 Tharo_3193 ac79200e98ee8091bea5fd7ec3cad16a 212 TIGRFAM TIGR00172 maf: septum formation protein Maf 6 198 1.6E-43 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 Tharo_3193 ac79200e98ee8091bea5fd7ec3cad16a 212 Hamap MF_00528 Septum formation protein Maf [maf]. 6 205 31.452 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 Tharo_3193 ac79200e98ee8091bea5fd7ec3cad16a 212 Gene3D G3DSA:3.90.950.10 2 204 5.3E-65 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Tharo_3193 ac79200e98ee8091bea5fd7ec3cad16a 212 PIRSF PIRSF006305 2 208 1.2E-43 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 Tharo_3193 ac79200e98ee8091bea5fd7ec3cad16a 212 Pfam PF02545 Maf-like protein 6 200 9.2E-52 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 Tharo_3193 ac79200e98ee8091bea5fd7ec3cad16a 212 SUPERFAMILY SSF52972 5 199 3.27E-56 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Tharo_0526 5321c72888186d14f84761f22c65bb74 469 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 386 398 - T 14-10-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Tharo_0526 5321c72888186d14f84761f22c65bb74 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 50 68 - T 14-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 Tharo_0526 5321c72888186d14f84761f22c65bb74 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 259 274 - T 14-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 Tharo_0526 5321c72888186d14f84761f22c65bb74 469 Gene3D G3DSA:3.30.590.10 105 457 2.8E-148 T 14-10-2018 Tharo_0526 5321c72888186d14f84761f22c65bb74 469 SUPERFAMILY SSF55931 102 468 4.22E-139 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Tharo_0526 5321c72888186d14f84761f22c65bb74 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 5 468 3.7E-198 T 14-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Tharo_0526 5321c72888186d14f84761f22c65bb74 469 SUPERFAMILY SSF54368 3 99 9.42E-33 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Tharo_0526 5321c72888186d14f84761f22c65bb74 469 SMART SM01230 102 379 6.4E-147 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Tharo_0526 5321c72888186d14f84761f22c65bb74 469 Pfam PF00120 Glutamine synthetase, catalytic domain 103 466 2.8E-138 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Tharo_0526 5321c72888186d14f84761f22c65bb74 469 Gene3D G3DSA:3.10.20.70 2 104 7.7E-34 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Tharo_0526 5321c72888186d14f84761f22c65bb74 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 14 95 4.1E-27 T 14-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 Tharo_2835 c89dec7161bfeb1ed5092009776d82e3 79 Gene3D G3DSA:1.10.10.1100 1 55 7.4E-20 T 14-10-2018 Tharo_2835 c89dec7161bfeb1ed5092009776d82e3 79 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 49 2.2E-9 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain Tharo_1285 e3694e273ff35a83adf7ad2afe9d4ee7 1162 SUPERFAMILY SSF53335 205 665 1.98E-42 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_1285 e3694e273ff35a83adf7ad2afe9d4ee7 1162 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 566 578 2.4E-8 T 14-10-2018 Tharo_1285 e3694e273ff35a83adf7ad2afe9d4ee7 1162 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 346 362 2.4E-8 T 14-10-2018 Tharo_1285 e3694e273ff35a83adf7ad2afe9d4ee7 1162 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 406 420 2.4E-8 T 14-10-2018 Tharo_1285 e3694e273ff35a83adf7ad2afe9d4ee7 1162 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 569 575 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Tharo_1727 22b780e37139835ef91af72e96ca1657 1251 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 2 1232 0.0 T 14-10-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 Tharo_1727 22b780e37139835ef91af72e96ca1657 1251 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 3 40 1.0E-18 T 14-10-2018 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 Tharo_1727 22b780e37139835ef91af72e96ca1657 1251 Gene3D G3DSA:3.40.50.12440 44 1242 0.0 T 14-10-2018 Tharo_1727 22b780e37139835ef91af72e96ca1657 1251 SUPERFAMILY SSF53706 3 1065 0.0 T 14-10-2018 Tharo_1727 22b780e37139835ef91af72e96ca1657 1251 Pfam PF01568 Molydopterin dinucleotide binding domain 1083 1194 1.1E-20 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 Tharo_1727 22b780e37139835ef91af72e96ca1657 1251 Pfam PF00384 Molybdopterin oxidoreductase 108 826 2.8E-140 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1727 22b780e37139835ef91af72e96ca1657 1251 SMART SM00926 43 105 2.2E-5 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1727 22b780e37139835ef91af72e96ca1657 1251 SUPERFAMILY SSF50692 1077 1230 2.01E-43 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Tharo_1727 22b780e37139835ef91af72e96ca1657 1251 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 48 66 - T 14-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 Tharo_3117 29462b71a4cc43b43c5faed8edbf6d3c 592 SMART SM00387 472 585 7.6E-31 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_3117 29462b71a4cc43b43c5faed8edbf6d3c 592 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 473 583 3.8E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_3117 29462b71a4cc43b43c5faed8edbf6d3c 592 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 544 5.8E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3117 29462b71a4cc43b43c5faed8edbf6d3c 592 PRINTS PR00344 Bacterial sensor protein C-terminal signature 545 563 5.8E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3117 29462b71a4cc43b43c5faed8edbf6d3c 592 PRINTS PR00344 Bacterial sensor protein C-terminal signature 516 530 5.8E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3117 29462b71a4cc43b43c5faed8edbf6d3c 592 PRINTS PR00344 Bacterial sensor protein C-terminal signature 569 582 5.8E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3117 29462b71a4cc43b43c5faed8edbf6d3c 592 Gene3D G3DSA:3.30.565.10 431 589 1.7E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_3117 29462b71a4cc43b43c5faed8edbf6d3c 592 Pfam PF00512 His Kinase A (phospho-acceptor) domain 365 428 1.5E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_3117 29462b71a4cc43b43c5faed8edbf6d3c 592 SUPERFAMILY SSF103190 67 191 8.24E-9 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily Tharo_3117 29462b71a4cc43b43c5faed8edbf6d3c 592 Pfam PF14827 Double sensory domain of two-component sensor kinase 56 299 1.5E-17 T 14-10-2018 IPR029150 Double Cache domain 3 Tharo_3117 29462b71a4cc43b43c5faed8edbf6d3c 592 Gene3D G3DSA:1.10.287.130 326 428 3.0E-16 T 14-10-2018 Tharo_3117 29462b71a4cc43b43c5faed8edbf6d3c 592 SUPERFAMILY SSF55874 422 583 8.38E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_3117 29462b71a4cc43b43c5faed8edbf6d3c 592 SUPERFAMILY SSF47384 360 428 1.57E-9 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_3117 29462b71a4cc43b43c5faed8edbf6d3c 592 SMART SM00388 365 431 1.3E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_0836 4d2d630a1b9d0d35a5d9e6e10d6d5c82 361 Pfam PF05598 Transposase domain (DUF772) 53 125 1.5E-22 T 14-10-2018 IPR008490 Transposase InsH, N-terminal Tharo_0836 4d2d630a1b9d0d35a5d9e6e10d6d5c82 361 Pfam PF01609 Transposase DDE domain 210 352 3.3E-12 T 14-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 Tharo_2043 4d2d630a1b9d0d35a5d9e6e10d6d5c82 361 Pfam PF05598 Transposase domain (DUF772) 53 125 1.5E-22 T 14-10-2018 IPR008490 Transposase InsH, N-terminal Tharo_2043 4d2d630a1b9d0d35a5d9e6e10d6d5c82 361 Pfam PF01609 Transposase DDE domain 210 352 3.3E-12 T 14-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 Tharo_2672 4d2d630a1b9d0d35a5d9e6e10d6d5c82 361 Pfam PF05598 Transposase domain (DUF772) 53 125 1.5E-22 T 14-10-2018 IPR008490 Transposase InsH, N-terminal Tharo_2672 4d2d630a1b9d0d35a5d9e6e10d6d5c82 361 Pfam PF01609 Transposase DDE domain 210 352 3.3E-12 T 14-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 Tharo_3389 219ca157ff5857cfd3549ee982f187d0 415 SMART SM00448 2 114 1.2E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_3389 219ca157ff5857cfd3549ee982f187d0 415 SUPERFAMILY SSF52172 1 132 1.1E-37 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_3389 219ca157ff5857cfd3549ee982f187d0 415 Gene3D G3DSA:1.10.8.60 269 346 4.3E-8 T 14-10-2018 Tharo_3389 219ca157ff5857cfd3549ee982f187d0 415 SUPERFAMILY SSF46689 347 406 2.73E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_3389 219ca157ff5857cfd3549ee982f187d0 415 Pfam PF14532 Sigma-54 interaction domain 136 268 2.3E-21 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Tharo_3389 219ca157ff5857cfd3549ee982f187d0 415 Pfam PF00072 Response regulator receiver domain 4 115 9.7E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_3389 219ca157ff5857cfd3549ee982f187d0 415 Gene3D G3DSA:3.40.50.300 130 268 3.7E-15 T 14-10-2018 Tharo_3389 219ca157ff5857cfd3549ee982f187d0 415 Pfam PF02954 Bacterial regulatory protein, Fis family 364 404 5.0E-6 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_3389 219ca157ff5857cfd3549ee982f187d0 415 Gene3D G3DSA:1.10.10.60 354 408 2.7E-14 T 14-10-2018 Tharo_3389 219ca157ff5857cfd3549ee982f187d0 415 SUPERFAMILY SSF52540 174 340 7.34E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3389 219ca157ff5857cfd3549ee982f187d0 415 Gene3D G3DSA:3.40.50.2300 1 128 3.6E-35 T 14-10-2018 Tharo_1192 8d20b8b572afa9429cfee50aafc5e2cb 431 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 43 66 - T 14-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 Tharo_1192 8d20b8b572afa9429cfee50aafc5e2cb 431 Gene3D G3DSA:3.90.190.20 293 430 6.8E-29 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Tharo_1192 8d20b8b572afa9429cfee50aafc5e2cb 431 Pfam PF08245 Mur ligase middle domain 45 185 2.1E-9 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Tharo_1192 8d20b8b572afa9429cfee50aafc5e2cb 431 TIGRFAM TIGR01499 folC: bifunctional protein FolC 24 423 4.3E-92 T 14-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 Tharo_1192 8d20b8b572afa9429cfee50aafc5e2cb 431 SUPERFAMILY SSF53244 291 425 5.49E-28 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Tharo_1192 8d20b8b572afa9429cfee50aafc5e2cb 431 Gene3D G3DSA:3.40.1190.10 2 292 5.0E-86 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Tharo_1192 8d20b8b572afa9429cfee50aafc5e2cb 431 SUPERFAMILY SSF53623 4 288 2.75E-85 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Tharo_1192 8d20b8b572afa9429cfee50aafc5e2cb 431 PIRSF PIRSF001563 2 430 2.9E-100 T 14-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 Tharo_0406 3b73c4d4fed7f338ab5e447ca0bbe23f 765 Pfam PF00448 SRP54-type protein, GTPase domain 203 399 6.1E-29 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Tharo_0406 3b73c4d4fed7f338ab5e447ca0bbe23f 765 SMART SM00382 201 399 9.3E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0406 3b73c4d4fed7f338ab5e447ca0bbe23f 765 Gene3D G3DSA:1.20.120.1380 173 390 1.6E-46 T 14-10-2018 Tharo_0406 3b73c4d4fed7f338ab5e447ca0bbe23f 765 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 1 290 4.8E-63 T 14-10-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 Tharo_0406 3b73c4d4fed7f338ab5e447ca0bbe23f 765 SUPERFAMILY SSF52540 198 395 4.4E-27 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0406 3b73c4d4fed7f338ab5e447ca0bbe23f 765 Gene3D G3DSA:3.40.50.300 197 388 1.6E-46 T 14-10-2018 Tharo_0406 3b73c4d4fed7f338ab5e447ca0bbe23f 765 SMART SM00962 202 400 1.4E-39 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Tharo_1034 5d5a64540d62cc9df388a37cc6b623bd 160 SUPERFAMILY SSF47188 2 122 7.06E-22 T 14-10-2018 IPR035938 Hemerythrin-like superfamily Tharo_1034 5d5a64540d62cc9df388a37cc6b623bd 160 Gene3D G3DSA:1.20.120.50 3 127 1.3E-17 T 14-10-2018 IPR035938 Hemerythrin-like superfamily Tharo_1034 5d5a64540d62cc9df388a37cc6b623bd 160 Pfam PF01814 Hemerythrin HHE cation binding domain 17 115 3.6E-7 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 Tharo_1034 5d5a64540d62cc9df388a37cc6b623bd 160 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 6 119 9.8E-17 T 14-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 Tharo_3068 c4141cc71a52b46531c1224c84480475 331 SUPERFAMILY SSF54862 7 149 2.6E-22 T 14-10-2018 Tharo_3068 c4141cc71a52b46531c1224c84480475 331 PIRSF PIRSF000371 1 310 2.1E-116 T 14-10-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 Tharo_3068 c4141cc71a52b46531c1224c84480475 331 SUPERFAMILY SSF102114 91 273 3.92E-16 T 14-10-2018 Tharo_3068 c4141cc71a52b46531c1224c84480475 331 Pfam PF13353 4Fe-4S single cluster domain 16 158 2.5E-10 T 14-10-2018 Tharo_3068 c4141cc71a52b46531c1224c84480475 331 Pfam PF04055 Radical SAM superfamily 24 237 2.6E-26 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_3068 c4141cc71a52b46531c1224c84480475 331 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 55 66 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_3068 c4141cc71a52b46531c1224c84480475 331 Gene3D G3DSA:3.20.20.70 3 51 2.9E-17 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_3068 c4141cc71a52b46531c1224c84480475 331 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 6 301 8.2E-111 T 14-10-2018 Tharo_3068 c4141cc71a52b46531c1224c84480475 331 Gene3D G3DSA:3.80.30.10 128 310 4.4E-46 T 14-10-2018 Tharo_3068 c4141cc71a52b46531c1224c84480475 331 TIGRFAM TIGR04003 rSAM_BssD: [benzylsuccinate synthase]-activating enzyme 4 316 1.4E-197 T 14-10-2018 IPR023880 Benzylsuccinate synthase activating enzyme GO:0018805 Tharo_3068 c4141cc71a52b46531c1224c84480475 331 Gene3D G3DSA:3.30.70.20 52 117 8.8E-10 T 14-10-2018 Tharo_3068 c4141cc71a52b46531c1224c84480475 331 ProSitePatterns PS01087 Radical activating enzymes signature. 17 38 - T 14-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 Tharo_1026 08466f2f53860d0e2ecd61e6c50b03bd 636 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 354 2.2E-125 T 14-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 Tharo_1026 08466f2f53860d0e2ecd61e6c50b03bd 636 SUPERFAMILY SSF48019 243 361 3.91E-27 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 Tharo_1026 08466f2f53860d0e2ecd61e6c50b03bd 636 SMART SM00382 37 179 8.7E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1026 08466f2f53860d0e2ecd61e6c50b03bd 636 Pfam PF13177 DNA polymerase III, delta subunit 20 178 2.1E-40 T 14-10-2018 Tharo_1026 08466f2f53860d0e2ecd61e6c50b03bd 636 Gene3D G3DSA:1.20.272.10 242 361 4.0E-34 T 14-10-2018 Tharo_1026 08466f2f53860d0e2ecd61e6c50b03bd 636 SUPERFAMILY SSF52540 32 223 9.2E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1026 08466f2f53860d0e2ecd61e6c50b03bd 636 Gene3D G3DSA:3.30.300.150 523 618 2.7E-7 T 14-10-2018 IPR038249 DNA polymerase III, tau subunit, C-terminal domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_1026 08466f2f53860d0e2ecd61e6c50b03bd 636 Gene3D G3DSA:3.40.50.300 13 177 3.9E-102 T 14-10-2018 Tharo_1026 08466f2f53860d0e2ecd61e6c50b03bd 636 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 540 633 3.0E-8 T 14-10-2018 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_1026 08466f2f53860d0e2ecd61e6c50b03bd 636 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 360 3.3E-23 T 14-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 Tharo_1026 08466f2f53860d0e2ecd61e6c50b03bd 636 Gene3D G3DSA:1.10.8.60 8 240 3.9E-102 T 14-10-2018 Tharo_2188 72f32c9255dc1063f4f489883e467ce6 871 Gene3D G3DSA:3.20.20.80 40 313 1.1E-10 T 14-10-2018 Tharo_2188 72f32c9255dc1063f4f489883e467ce6 871 SUPERFAMILY SSF53448 412 689 1.41E-53 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_2188 72f32c9255dc1063f4f489883e467ce6 871 Pfam PF13641 Glycosyltransferase like family 2 426 655 1.0E-27 T 14-10-2018 Tharo_2188 72f32c9255dc1063f4f489883e467ce6 871 SUPERFAMILY SSF51445 56 306 3.45E-44 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily Tharo_2188 72f32c9255dc1063f4f489883e467ce6 871 Gene3D G3DSA:3.90.550.10 417 639 2.2E-62 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_2382 a14689af0f5a182be7a8adb677aef5f1 416 Gene3D G3DSA:3.40.640.10 37 286 7.5E-183 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_2382 a14689af0f5a182be7a8adb677aef5f1 416 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 14-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Tharo_2382 a14689af0f5a182be7a8adb677aef5f1 416 Pfam PF00464 Serine hydroxymethyltransferase 8 384 3.8E-168 T 14-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Tharo_2382 a14689af0f5a182be7a8adb677aef5f1 416 Gene3D G3DSA:3.90.1150.10 10 392 7.5E-183 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_2382 a14689af0f5a182be7a8adb677aef5f1 416 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 415 51.542 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Tharo_2382 a14689af0f5a182be7a8adb677aef5f1 416 SUPERFAMILY SSF53383 5 415 1.41E-176 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_2382 a14689af0f5a182be7a8adb677aef5f1 416 PIRSF PIRSF000412 1 416 1.1E-163 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Tharo_2705 1dd519a3c838ab0122039f85944c2902 145 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 142 3.5E-44 T 14-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2705 1dd519a3c838ab0122039f85944c2902 145 Gene3D G3DSA:3.100.10.10 67 144 2.0E-11 T 14-10-2018 Tharo_2705 1dd519a3c838ab0122039f85944c2902 145 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 142 2.5E-28 T 14-10-2018 IPR021131 Ribosomal protein L18e/L15P Tharo_2705 1dd519a3c838ab0122039f85944c2902 145 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 145 19.188 T 14-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 Tharo_2705 1dd519a3c838ab0122039f85944c2902 145 SUPERFAMILY SSF52080 4 142 1.15E-42 T 14-10-2018 IPR036227 Ribosomal L18e/L15P superfamily Tharo_2705 1dd519a3c838ab0122039f85944c2902 145 ProSitePatterns PS00475 Ribosomal protein L15 signature. 109 139 - T 14-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2552 26c143c51c4dd394b968cc800b0981e9 384 Gene3D G3DSA:3.40.50.2300 143 374 1.1E-99 T 14-10-2018 Tharo_2552 26c143c51c4dd394b968cc800b0981e9 384 Gene3D G3DSA:3.40.50.2300 28 365 1.1E-99 T 14-10-2018 Tharo_2552 26c143c51c4dd394b968cc800b0981e9 384 Pfam PF13458 Periplasmic binding protein 25 363 1.0E-47 T 14-10-2018 IPR028081 Leucine-binding protein domain Tharo_2552 26c143c51c4dd394b968cc800b0981e9 384 SUPERFAMILY SSF53822 26 382 6.09E-69 T 14-10-2018 IPR028082 Periplasmic binding protein-like I Tharo_3213 982aca9cbf2fdae60161076cd6890d90 274 SUPERFAMILY SSF53790 11 252 2.04E-37 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Tharo_3213 982aca9cbf2fdae60161076cd6890d90 274 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 14 244 1.6E-68 T 14-10-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 Tharo_3213 982aca9cbf2fdae60161076cd6890d90 274 Gene3D G3DSA:3.40.1010.10 12 142 4.0E-25 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Tharo_3213 982aca9cbf2fdae60161076cd6890d90 274 PIRSF PIRSF036427 12 252 9.5E-60 T 14-10-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 Tharo_3213 982aca9cbf2fdae60161076cd6890d90 274 Gene3D G3DSA:3.30.950.10 143 262 1.4E-26 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 Tharo_3213 982aca9cbf2fdae60161076cd6890d90 274 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 15 225 1.2E-38 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Tharo_0980 e2cac806c53c2a420e3be0b4cebdbfe9 456 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 28 210 1.1E-46 T 14-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 Tharo_0980 e2cac806c53c2a420e3be0b4cebdbfe9 456 Pfam PF01171 PP-loop family 28 206 1.3E-46 T 14-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 Tharo_0980 e2cac806c53c2a420e3be0b4cebdbfe9 456 Gene3D G3DSA:3.40.50.620 19 238 4.1E-66 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_0980 e2cac806c53c2a420e3be0b4cebdbfe9 456 SUPERFAMILY SSF82829 245 323 6.02E-14 T 14-10-2018 Tharo_0980 e2cac806c53c2a420e3be0b4cebdbfe9 456 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 13 312 21.48 T 14-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 Tharo_0980 e2cac806c53c2a420e3be0b4cebdbfe9 456 Gene3D G3DSA:1.20.59.20 239 322 1.8E-5 T 14-10-2018 Tharo_0980 e2cac806c53c2a420e3be0b4cebdbfe9 456 SUPERFAMILY SSF52402 24 240 8.38E-54 T 14-10-2018 Tharo_0980 e2cac806c53c2a420e3be0b4cebdbfe9 456 SUPERFAMILY SSF56037 333 443 3.66E-22 T 14-10-2018 Tharo_0980 e2cac806c53c2a420e3be0b4cebdbfe9 456 Pfam PF09179 TilS substrate binding domain 253 320 4.9E-9 T 14-10-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 Tharo_0980 e2cac806c53c2a420e3be0b4cebdbfe9 456 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 370 412 9.3E-10 T 14-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 Tharo_0980 e2cac806c53c2a420e3be0b4cebdbfe9 456 Pfam PF11734 TilS substrate C-terminal domain 369 440 1.1E-20 T 14-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 Tharo_0980 e2cac806c53c2a420e3be0b4cebdbfe9 456 SMART SM00977 369 442 1.7E-22 T 14-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 Tharo_1116 f5b0d58b8079e089f5bd3a816445fdcf 326 SUPERFAMILY SSF53850 90 296 1.1E-44 T 14-10-2018 Tharo_1116 f5b0d58b8079e089f5bd3a816445fdcf 326 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 1.2E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1116 f5b0d58b8079e089f5bd3a816445fdcf 326 Gene3D G3DSA:3.40.190.10 92 292 1.6E-70 T 14-10-2018 Tharo_1116 f5b0d58b8079e089f5bd3a816445fdcf 326 Pfam PF03466 LysR substrate binding domain 95 297 2.9E-22 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_1116 f5b0d58b8079e089f5bd3a816445fdcf 326 SUPERFAMILY SSF46785 2 85 1.84E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1116 f5b0d58b8079e089f5bd3a816445fdcf 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.4E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1116 f5b0d58b8079e089f5bd3a816445fdcf 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.4E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1116 f5b0d58b8079e089f5bd3a816445fdcf 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.4E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1116 f5b0d58b8079e089f5bd3a816445fdcf 326 Gene3D G3DSA:1.10.10.10 1 88 4.5E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1116 f5b0d58b8079e089f5bd3a816445fdcf 326 Gene3D G3DSA:3.40.190.10 170 268 1.6E-70 T 14-10-2018 Tharo_0333 3bc7b861e64258db9961a93895ffbd84 429 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 351 428 6.6E-21 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain Tharo_0333 3bc7b861e64258db9961a93895ffbd84 429 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 1 411 9.7E-95 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G Tharo_0333 3bc7b861e64258db9961a93895ffbd84 429 SUPERFAMILY SSF117143 75 390 1.24E-66 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like Tharo_0333 3bc7b861e64258db9961a93895ffbd84 429 Gene3D G3DSA:2.60.98.20 151 311 1.8E-18 T 14-10-2018 IPR037058 Flagellar hook protein FlgE superfamily Tharo_0333 3bc7b861e64258db9961a93895ffbd84 429 Pfam PF07559 Flagellar basal body protein FlaE 195 310 3.3E-21 T 14-10-2018 IPR011491 Flagellar hook protein FlgE Tharo_0333 3bc7b861e64258db9961a93895ffbd84 429 Pfam PF00460 Flagella basal body rod protein 4 33 1.8E-9 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 Tharo_1119 c43df1e6433d3270271cbbe1f70697a2 621 SUPERFAMILY SSF56801 27 505 4.19E-76 T 14-10-2018 Tharo_1119 c43df1e6433d3270271cbbe1f70697a2 621 Pfam PF00501 AMP-binding enzyme 47 456 2.6E-52 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Tharo_1119 c43df1e6433d3270271cbbe1f70697a2 621 Gene3D G3DSA:3.40.50.12780 36 457 2.3E-61 T 14-10-2018 Tharo_0250 5cef04ddd5fb8aedc651322313d8d24f 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 1.2E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_0250 5cef04ddd5fb8aedc651322313d8d24f 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 1.2E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_0250 5cef04ddd5fb8aedc651322313d8d24f 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 113 126 1.2E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_0250 5cef04ddd5fb8aedc651322313d8d24f 293 Pfam PF00561 alpha/beta hydrolase fold 29 276 8.8E-22 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_0250 5cef04ddd5fb8aedc651322313d8d24f 293 SUPERFAMILY SSF53474 8 288 1.74E-50 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_0250 5cef04ddd5fb8aedc651322313d8d24f 293 Gene3D G3DSA:3.40.50.1820 7 284 1.4E-59 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_3031 2879e2dc12e3fda52d22675f23cbb6a6 538 Gene3D G3DSA:3.40.720.10 171 465 1.0E-32 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 Tharo_3031 2879e2dc12e3fda52d22675f23cbb6a6 538 Pfam PF00884 Sulfatase 179 461 3.0E-16 T 14-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 Tharo_3031 2879e2dc12e3fda52d22675f23cbb6a6 538 SUPERFAMILY SSF53649 176 507 1.11E-31 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 Tharo_2013 2fc8178e72795b75734cfcced51904ae 287 SMART SM00062 28 258 5.5E-6 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Tharo_2013 2fc8178e72795b75734cfcced51904ae 287 Gene3D G3DSA:3.40.190.10 113 221 9.1E-68 T 14-10-2018 Tharo_2013 2fc8178e72795b75734cfcced51904ae 287 TIGRFAM TIGR04553 ABC_peri_selen: putative selenate ABC transporter periplasmic binding protein 28 287 1.1E-107 T 14-10-2018 IPR030836 Putative ABC transporter periplasmic binding protein PhnD-like Tharo_2013 2fc8178e72795b75734cfcced51904ae 287 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 24 246 1.1E-72 T 14-10-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 Tharo_2013 2fc8178e72795b75734cfcced51904ae 287 Gene3D G3DSA:3.40.190.10 32 251 9.1E-68 T 14-10-2018 Tharo_2013 2fc8178e72795b75734cfcced51904ae 287 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 32 273 8.4E-71 T 14-10-2018 Tharo_2013 2fc8178e72795b75734cfcced51904ae 287 SUPERFAMILY SSF53850 46 236 4.0E-41 T 14-10-2018 Tharo_3119 3ec077eaecb44e0d87490d51a3008a5a 643 Pfam PF16326 ABC transporter C-terminal domain 572 635 1.4E-11 T 14-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 Tharo_3119 3ec077eaecb44e0d87490d51a3008a5a 643 SMART SM00382 337 510 5.8E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_3119 3ec077eaecb44e0d87490d51a3008a5a 643 SMART SM00382 26 223 2.6E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_3119 3ec077eaecb44e0d87490d51a3008a5a 643 Gene3D G3DSA:3.40.50.300 275 543 7.1E-56 T 14-10-2018 Tharo_3119 3ec077eaecb44e0d87490d51a3008a5a 643 Gene3D G3DSA:1.10.287.380 569 638 6.6E-6 T 14-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 Tharo_3119 3ec077eaecb44e0d87490d51a3008a5a 643 Pfam PF12848 ABC transporter 217 295 2.1E-28 T 14-10-2018 IPR032781 ABC-transporter extension domain Tharo_3119 3ec077eaecb44e0d87490d51a3008a5a 643 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_3119 3ec077eaecb44e0d87490d51a3008a5a 643 SUPERFAMILY SSF52540 2 256 4.42E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3119 3ec077eaecb44e0d87490d51a3008a5a 643 Pfam PF00005 ABC transporter 328 466 1.9E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_3119 3ec077eaecb44e0d87490d51a3008a5a 643 SUPERFAMILY SSF52540 295 522 2.9E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3119 3ec077eaecb44e0d87490d51a3008a5a 643 Pfam PF00005 ABC transporter 19 178 9.0E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_3119 3ec077eaecb44e0d87490d51a3008a5a 643 Gene3D G3DSA:3.40.50.300 7 273 1.7E-54 T 14-10-2018 Tharo_3119 3ec077eaecb44e0d87490d51a3008a5a 643 ProSitePatterns PS00211 ABC transporters family signature. 438 452 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_3136 23a2aed3cfa55124e1dae0e94a1312d4 284 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 89 155 6.5E-9 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Tharo_3136 23a2aed3cfa55124e1dae0e94a1312d4 284 SUPERFAMILY SSF53254 88 248 5.39E-12 T 14-10-2018 IPR029033 Histidine phosphatase superfamily Tharo_3136 23a2aed3cfa55124e1dae0e94a1312d4 284 Gene3D G3DSA:3.40.50.1240 81 262 4.8E-12 T 14-10-2018 IPR029033 Histidine phosphatase superfamily Tharo_0411 60756aab6c8c9fb92892f4a92b4ac886 970 SMART SM00267 794 968 2.2E-52 T 14-10-2018 IPR000160 GGDEF domain Tharo_0411 60756aab6c8c9fb92892f4a92b4ac886 970 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 256 3.1E-33 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Tharo_0411 60756aab6c8c9fb92892f4a92b4ac886 970 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 801 967 7.2E-43 T 14-10-2018 IPR000160 GGDEF domain Tharo_0411 60756aab6c8c9fb92892f4a92b4ac886 970 Gene3D G3DSA:3.40.190.10 122 216 6.6E-39 T 14-10-2018 Tharo_0411 60756aab6c8c9fb92892f4a92b4ac886 970 Gene3D G3DSA:3.40.190.10 526 752 1.1E-57 T 14-10-2018 Tharo_0411 60756aab6c8c9fb92892f4a92b4ac886 970 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 537 752 6.4E-27 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Tharo_0411 60756aab6c8c9fb92892f4a92b4ac886 970 Gene3D G3DSA:3.40.190.10 621 715 1.1E-57 T 14-10-2018 Tharo_0411 60756aab6c8c9fb92892f4a92b4ac886 970 Gene3D G3DSA:3.40.190.10 368 466 2.6E-52 T 14-10-2018 Tharo_0411 60756aab6c8c9fb92892f4a92b4ac886 970 Gene3D G3DSA:3.40.190.10 284 503 2.6E-52 T 14-10-2018 Tharo_0411 60756aab6c8c9fb92892f4a92b4ac886 970 SUPERFAMILY SSF53850 537 753 1.66E-40 T 14-10-2018 Tharo_0411 60756aab6c8c9fb92892f4a92b4ac886 970 Gene3D G3DSA:3.30.70.270 791 968 4.5E-54 T 14-10-2018 Tharo_0411 60756aab6c8c9fb92892f4a92b4ac886 970 SUPERFAMILY SSF53850 286 506 1.35E-41 T 14-10-2018 Tharo_0411 60756aab6c8c9fb92892f4a92b4ac886 970 SUPERFAMILY SSF55073 810 967 5.89E-44 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_0411 60756aab6c8c9fb92892f4a92b4ac886 970 SMART SM00062 536 756 1.9E-26 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Tharo_0411 60756aab6c8c9fb92892f4a92b4ac886 970 SMART SM00062 285 507 1.6E-23 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Tharo_0411 60756aab6c8c9fb92892f4a92b4ac886 970 SMART SM00062 38 260 5.7E-15 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Tharo_0411 60756aab6c8c9fb92892f4a92b4ac886 970 Pfam PF00990 Diguanylate cyclase, GGDEF domain 807 964 2.7E-41 T 14-10-2018 IPR000160 GGDEF domain Tharo_0411 60756aab6c8c9fb92892f4a92b4ac886 970 SUPERFAMILY SSF53850 39 257 8.36E-38 T 14-10-2018 Tharo_0411 60756aab6c8c9fb92892f4a92b4ac886 970 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 286 505 3.5E-36 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Tharo_0411 60756aab6c8c9fb92892f4a92b4ac886 970 Gene3D G3DSA:3.40.190.10 37 256 6.6E-39 T 14-10-2018 Tharo_1018 98493c200ff2e9b7e2e614d7901555b1 560 Pfam PF01627 Hpt domain 17 96 3.2E-8 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Tharo_1018 98493c200ff2e9b7e2e614d7901555b1 560 SUPERFAMILY SSF55073 398 551 6.2E-43 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_1018 98493c200ff2e9b7e2e614d7901555b1 560 SMART SM00267 382 553 2.5E-41 T 14-10-2018 IPR000160 GGDEF domain Tharo_1018 98493c200ff2e9b7e2e614d7901555b1 560 Gene3D G3DSA:1.20.120.160 6 110 1.3E-8 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 Tharo_1018 98493c200ff2e9b7e2e614d7901555b1 560 SUPERFAMILY SSF47226 15 111 4.06E-11 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 Tharo_1018 98493c200ff2e9b7e2e614d7901555b1 560 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 392 551 3.9E-44 T 14-10-2018 IPR000160 GGDEF domain Tharo_1018 98493c200ff2e9b7e2e614d7901555b1 560 SMART SM00448 266 379 1.3E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1018 98493c200ff2e9b7e2e614d7901555b1 560 SMART SM00448 140 254 4.6E-13 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1018 98493c200ff2e9b7e2e614d7901555b1 560 Gene3D G3DSA:3.30.70.270 390 557 1.1E-47 T 14-10-2018 Tharo_1018 98493c200ff2e9b7e2e614d7901555b1 560 SUPERFAMILY SSF52172 142 259 1.41E-20 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1018 98493c200ff2e9b7e2e614d7901555b1 560 Pfam PF00072 Response regulator receiver domain 142 254 4.4E-14 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1018 98493c200ff2e9b7e2e614d7901555b1 560 Pfam PF00072 Response regulator receiver domain 268 379 3.4E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1018 98493c200ff2e9b7e2e614d7901555b1 560 Gene3D G3DSA:3.40.50.2300 261 389 3.2E-30 T 14-10-2018 Tharo_1018 98493c200ff2e9b7e2e614d7901555b1 560 Gene3D G3DSA:3.40.50.2300 141 260 1.8E-19 T 14-10-2018 Tharo_1018 98493c200ff2e9b7e2e614d7901555b1 560 Pfam PF00990 Diguanylate cyclase, GGDEF domain 395 549 6.8E-37 T 14-10-2018 IPR000160 GGDEF domain Tharo_1018 98493c200ff2e9b7e2e614d7901555b1 560 SUPERFAMILY SSF52172 264 397 1.29E-32 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_0844 7451d95def7b5f3cfa0809dc84eafd76 453 Gene3D G3DSA:3.90.550.10 1 223 3.8E-60 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_0844 7451d95def7b5f3cfa0809dc84eafd76 453 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 1 450 1.4E-184 T 14-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 Tharo_0844 7451d95def7b5f3cfa0809dc84eafd76 453 SUPERFAMILY SSF53448 1 248 1.78E-60 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_0844 7451d95def7b5f3cfa0809dc84eafd76 453 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 1 448 40.924 T 14-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 Tharo_0844 7451d95def7b5f3cfa0809dc84eafd76 453 SUPERFAMILY SSF51161 250 433 2.01E-50 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily Tharo_0844 7451d95def7b5f3cfa0809dc84eafd76 453 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 391 425 1.4E-6 T 14-10-2018 IPR001451 Hexapeptide repeat Tharo_0844 7451d95def7b5f3cfa0809dc84eafd76 453 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 316 347 7.6E-6 T 14-10-2018 IPR001451 Hexapeptide repeat Tharo_0844 7451d95def7b5f3cfa0809dc84eafd76 453 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 264 296 3.8E-6 T 14-10-2018 IPR001451 Hexapeptide repeat Tharo_0844 7451d95def7b5f3cfa0809dc84eafd76 453 Gene3D G3DSA:2.160.10.10 224 452 1.1E-66 T 14-10-2018 Tharo_0844 7451d95def7b5f3cfa0809dc84eafd76 453 Pfam PF12804 MobA-like NTP transferase domain 3 152 5.1E-23 T 14-10-2018 IPR025877 MobA-like NTP transferase Tharo_2343 fc7b019e7a2136b6f7aaf5ce14b85fc7 582 SUPERFAMILY SSF55826 218 398 3.27E-33 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 Tharo_2343 fc7b019e7a2136b6f7aaf5ce14b85fc7 582 Gene3D G3DSA:3.90.960.10 240 398 3.7E-231 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 Tharo_2343 fc7b019e7a2136b6f7aaf5ce14b85fc7 582 Pfam PF04073 Aminoacyl-tRNA editing domain 257 387 4.3E-30 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 Tharo_2343 fc7b019e7a2136b6f7aaf5ce14b85fc7 582 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 580 40.828 T 14-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 Tharo_2343 fc7b019e7a2136b6f7aaf5ce14b85fc7 582 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 468 1.1E-46 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_2343 fc7b019e7a2136b6f7aaf5ce14b85fc7 582 SUPERFAMILY SSF55681 10 487 1.11E-101 T 14-10-2018 Tharo_2343 fc7b019e7a2136b6f7aaf5ce14b85fc7 582 PIRSF PIRSF001535 1 582 2.1E-267 T 14-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 Tharo_2343 fc7b019e7a2136b6f7aaf5ce14b85fc7 582 SUPERFAMILY SSF52954 473 580 7.2E-31 T 14-10-2018 Tharo_2343 fc7b019e7a2136b6f7aaf5ce14b85fc7 582 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 570 1.4E-221 T 14-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 Tharo_2343 fc7b019e7a2136b6f7aaf5ce14b85fc7 582 Gene3D G3DSA:3.40.50.800 4 562 3.7E-231 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily Tharo_2343 fc7b019e7a2136b6f7aaf5ce14b85fc7 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 1.0E-18 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 Tharo_2343 fc7b019e7a2136b6f7aaf5ce14b85fc7 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 1.0E-18 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 Tharo_2343 fc7b019e7a2136b6f7aaf5ce14b85fc7 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 1.0E-18 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 Tharo_2343 fc7b019e7a2136b6f7aaf5ce14b85fc7 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 1.0E-18 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 Tharo_2343 fc7b019e7a2136b6f7aaf5ce14b85fc7 582 Pfam PF03129 Anticodon binding domain 484 575 1.0E-16 T 14-10-2018 IPR004154 Anticodon-binding Tharo_2343 fc7b019e7a2136b6f7aaf5ce14b85fc7 582 Gene3D G3DSA:3.30.930.10 11 474 3.7E-231 T 14-10-2018 Tharo_1917 292c6a22f74b7fe18e546ddfc0165f25 417 Gene3D G3DSA:1.10.645.20 4 417 9.7E-178 T 14-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1917 292c6a22f74b7fe18e546ddfc0165f25 417 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 417 4.6E-126 T 14-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1917 292c6a22f74b7fe18e546ddfc0165f25 417 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 43 54 - T 14-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1917 292c6a22f74b7fe18e546ddfc0165f25 417 SUPERFAMILY SSF56762 16 417 1.05E-141 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1917 292c6a22f74b7fe18e546ddfc0165f25 417 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 1 417 51.212 T 14-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1917 292c6a22f74b7fe18e546ddfc0165f25 417 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 6 417 2.1E-191 T 14-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_3178 333788988d7f933db8dcefd5f8d8ff93 257 SMART SM00052 3 234 7.3E-9 T 14-10-2018 IPR001633 EAL domain Tharo_3178 333788988d7f933db8dcefd5f8d8ff93 257 SUPERFAMILY SSF141868 8 233 2.35E-42 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_3178 333788988d7f933db8dcefd5f8d8ff93 257 Gene3D G3DSA:3.20.20.450 7 240 2.1E-41 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_3178 333788988d7f933db8dcefd5f8d8ff93 257 Pfam PF00563 EAL domain 8 232 5.0E-37 T 14-10-2018 IPR001633 EAL domain Tharo_1694 47f674071e17c8003324da4b91fb8709 161 Gene3D G3DSA:3.30.70.860 3 160 3.1E-54 T 14-10-2018 IPR035571 UPF0234-like, C-terminal Tharo_1694 47f674071e17c8003324da4b91fb8709 161 SUPERFAMILY SSF89963 2 87 1.18E-27 T 14-10-2018 IPR036183 YajQ-like superfamily Tharo_1694 47f674071e17c8003324da4b91fb8709 161 Gene3D G3DSA:3.30.70.990 9 98 3.1E-54 T 14-10-2018 IPR035570 UPF0234, N-terminal Tharo_1694 47f674071e17c8003324da4b91fb8709 161 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 161 26.121 T 14-10-2018 IPR007551 Protein of unknown function DUF520 Tharo_1694 47f674071e17c8003324da4b91fb8709 161 Pfam PF04461 Protein of unknown function (DUF520) 2 160 1.3E-62 T 14-10-2018 IPR007551 Protein of unknown function DUF520 Tharo_1694 47f674071e17c8003324da4b91fb8709 161 SUPERFAMILY SSF89963 88 161 5.75E-26 T 14-10-2018 IPR036183 YajQ-like superfamily Tharo_0289 2298d697a62fb293b241c07cb9eeb9d4 404 PIRSF PIRSF000521 3 149 5.3E-10 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Tharo_0289 2298d697a62fb293b241c07cb9eeb9d4 404 PIRSF PIRSF000521 160 387 3.0E-32 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Tharo_0289 2298d697a62fb293b241c07cb9eeb9d4 404 SUPERFAMILY SSF53383 2 385 5.77E-125 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_0289 2298d697a62fb293b241c07cb9eeb9d4 404 Gene3D G3DSA:3.40.640.10 47 293 5.4E-139 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_0289 2298d697a62fb293b241c07cb9eeb9d4 404 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 4 384 2.0E-138 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 Tharo_0289 2298d697a62fb293b241c07cb9eeb9d4 404 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 211 248 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Tharo_0289 2298d697a62fb293b241c07cb9eeb9d4 404 Pfam PF00202 Aminotransferase class-III 12 384 3.2E-108 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Tharo_0289 2298d697a62fb293b241c07cb9eeb9d4 404 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 3 388 68.336 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 Tharo_0289 2298d697a62fb293b241c07cb9eeb9d4 404 Gene3D G3DSA:3.90.1150.10 12 377 5.4E-139 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_2713 ea82add918d8934dce0627d574ff86d9 105 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 2 97 21.086 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2713 ea82add918d8934dce0627d574ff86d9 105 SMART SM00739 3 30 9.6E-4 T 14-10-2018 IPR005824 KOW Tharo_2713 ea82add918d8934dce0627d574ff86d9 105 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 101 2.4E-25 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2713 ea82add918d8934dce0627d574ff86d9 105 SUPERFAMILY SSF50104 3 101 3.01E-32 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily Tharo_2713 ea82add918d8934dce0627d574ff86d9 105 Gene3D G3DSA:2.30.30.30 1 104 2.2E-37 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 Tharo_2713 ea82add918d8934dce0627d574ff86d9 105 ProSitePatterns PS01108 Ribosomal protein L24 signature. 7 24 - T 14-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2713 ea82add918d8934dce0627d574ff86d9 105 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 102 6.8E-37 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1705 465f5066457c8e671b358c264f646d31 389 Pfam PF11062 Protein of unknown function (DUF2863) 5 386 3.5E-162 T 14-10-2018 IPR021292 Protein of unknown function DUF2863 Tharo_2530 7436ca4021000eb7c073f00fec518177 317 Gene3D G3DSA:3.40.1550.10 128 279 8.1E-14 T 14-10-2018 IPR028976 CheC-like superfamily Tharo_2530 7436ca4021000eb7c073f00fec518177 317 Pfam PF13690 Chemotaxis phosphatase CheX 171 270 8.7E-17 T 14-10-2018 IPR028051 Chemotaxis phosphatase CheX-like domain Tharo_1661 9be08a3787b9db50f5a83bf31481832f 945 SUPERFAMILY SSF52374 3 665 2.48E-133 T 14-10-2018 Tharo_1661 9be08a3787b9db50f5a83bf31481832f 945 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 15 858 2.7E-258 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Tharo_1661 9be08a3787b9db50f5a83bf31481832f 945 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 2 936 20.83 T 14-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 Tharo_1661 9be08a3787b9db50f5a83bf31481832f 945 Gene3D G3DSA:3.90.740.10 192 417 3.0E-220 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Tharo_1661 9be08a3787b9db50f5a83bf31481832f 945 SUPERFAMILY SSF47323 669 935 3.27E-66 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_1661 9be08a3787b9db50f5a83bf31481832f 945 Pfam PF08264 Anticodon-binding domain of tRNA 702 857 1.5E-26 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 Tharo_1661 9be08a3787b9db50f5a83bf31481832f 945 Pfam PF06827 Zinc finger found in FPG and IleRS 906 933 4.1E-9 T 14-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 Tharo_1661 9be08a3787b9db50f5a83bf31481832f 945 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 51 62 3.8E-31 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Tharo_1661 9be08a3787b9db50f5a83bf31481832f 945 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 410 425 3.8E-31 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Tharo_1661 9be08a3787b9db50f5a83bf31481832f 945 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 241 264 3.8E-31 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Tharo_1661 9be08a3787b9db50f5a83bf31481832f 945 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 578 587 3.8E-31 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Tharo_1661 9be08a3787b9db50f5a83bf31481832f 945 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 540 553 3.8E-31 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Tharo_1661 9be08a3787b9db50f5a83bf31481832f 945 SUPERFAMILY SSF50677 202 412 8.16E-48 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Tharo_1661 9be08a3787b9db50f5a83bf31481832f 945 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 28 657 1.3E-189 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_1661 9be08a3787b9db50f5a83bf31481832f 945 Gene3D G3DSA:1.10.730.20 657 936 1.4E-84 T 14-10-2018 Tharo_1661 9be08a3787b9db50f5a83bf31481832f 945 Gene3D G3DSA:3.40.50.620 25 646 3.0E-220 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_1661 9be08a3787b9db50f5a83bf31481832f 945 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 58 69 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_0849 06df869fb6bf2328cdbf0b2636ab78da 371 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 4 371 1.6E-221 T 14-10-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 Tharo_0849 06df869fb6bf2328cdbf0b2636ab78da 371 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 63 77 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 Tharo_0849 06df869fb6bf2328cdbf0b2636ab78da 371 Gene3D G3DSA:3.40.50.720 176 314 2.1E-151 T 14-10-2018 Tharo_0849 06df869fb6bf2328cdbf0b2636ab78da 371 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 156 1.2E-25 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Tharo_0849 06df869fb6bf2328cdbf0b2636ab78da 371 Gene3D G3DSA:3.90.180.10 8 366 2.1E-151 T 14-10-2018 Tharo_0849 06df869fb6bf2328cdbf0b2636ab78da 371 SMART SM00829 12 369 0.0014 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Tharo_0849 06df869fb6bf2328cdbf0b2636ab78da 371 SUPERFAMILY SSF50129 2 187 4.28E-72 T 14-10-2018 IPR011032 GroES-like superfamily Tharo_0849 06df869fb6bf2328cdbf0b2636ab78da 371 SUPERFAMILY SSF51735 162 335 1.28E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_0849 06df869fb6bf2328cdbf0b2636ab78da 371 SUPERFAMILY SSF50129 321 371 1.65E-10 T 14-10-2018 IPR011032 GroES-like superfamily Tharo_0849 06df869fb6bf2328cdbf0b2636ab78da 371 Pfam PF00107 Zinc-binding dehydrogenase 199 331 3.7E-25 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Tharo_0353 7a36738034e0a9a03c49bc8da9367f0b 337 Gene3D G3DSA:1.10.220.30 7 92 1.1E-17 T 14-10-2018 Tharo_0353 7a36738034e0a9a03c49bc8da9367f0b 337 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 12 336 1.7E-114 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Tharo_0353 7a36738034e0a9a03c49bc8da9367f0b 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 200 225 9.0E-64 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Tharo_0353 7a36738034e0a9a03c49bc8da9367f0b 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 277 303 9.0E-64 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Tharo_0353 7a36738034e0a9a03c49bc8da9367f0b 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 39 65 9.0E-64 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Tharo_0353 7a36738034e0a9a03c49bc8da9367f0b 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 253 273 9.0E-64 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Tharo_0353 7a36738034e0a9a03c49bc8da9367f0b 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 231 251 9.0E-64 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Tharo_0353 7a36738034e0a9a03c49bc8da9367f0b 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 120 143 9.0E-64 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Tharo_0353 7a36738034e0a9a03c49bc8da9367f0b 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 10 26 9.0E-64 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Tharo_0353 7a36738034e0a9a03c49bc8da9367f0b 337 Gene3D G3DSA:1.10.220.30 200 337 1.4E-43 T 14-10-2018 Tharo_0353 7a36738034e0a9a03c49bc8da9367f0b 337 SUPERFAMILY SSF48029 12 110 6.15E-20 T 14-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical Tharo_0353 7a36738034e0a9a03c49bc8da9367f0b 337 SUPERFAMILY SSF48029 121 330 8.76E-65 T 14-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical Tharo_0353 7a36738034e0a9a03c49bc8da9367f0b 337 Gene3D G3DSA:1.10.220.30 96 196 3.8E-24 T 14-10-2018 Tharo_0353 7a36738034e0a9a03c49bc8da9367f0b 337 Pfam PF14841 FliG middle domain 122 191 5.7E-25 T 14-10-2018 IPR032779 Flagellar motor switch protein FliG, middle domain Tharo_0353 7a36738034e0a9a03c49bc8da9367f0b 337 Pfam PF14842 FliG N-terminal domain 11 109 2.3E-27 T 14-10-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain Tharo_0353 7a36738034e0a9a03c49bc8da9367f0b 337 Pfam PF01706 FliG C-terminal domain 224 329 7.3E-38 T 14-10-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal Tharo_0353 7a36738034e0a9a03c49bc8da9367f0b 337 PIRSF PIRSF003161 6 337 1.0E-111 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Tharo_1939 12f8ec7f4aaa8d62578dba5b3b8db9c2 460 Gene3D G3DSA:3.40.190.10 31 249 6.7E-37 T 14-10-2018 Tharo_1939 12f8ec7f4aaa8d62578dba5b3b8db9c2 460 Pfam PF01464 Transglycosylase SLT domain 280 391 1.2E-22 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 Tharo_1939 12f8ec7f4aaa8d62578dba5b3b8db9c2 460 SUPERFAMILY SSF53850 33 253 1.54E-31 T 14-10-2018 Tharo_1939 12f8ec7f4aaa8d62578dba5b3b8db9c2 460 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 33 253 3.9E-20 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Tharo_1939 12f8ec7f4aaa8d62578dba5b3b8db9c2 460 SMART SM00062 32 254 1.1E-16 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Tharo_1939 12f8ec7f4aaa8d62578dba5b3b8db9c2 460 Gene3D G3DSA:1.10.530.10 273 441 2.0E-31 T 14-10-2018 Tharo_1939 12f8ec7f4aaa8d62578dba5b3b8db9c2 460 SUPERFAMILY SSF53955 233 388 1.16E-35 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily Tharo_1939 12f8ec7f4aaa8d62578dba5b3b8db9c2 460 Gene3D G3DSA:3.40.190.10 116 211 6.7E-37 T 14-10-2018 Tharo_1939 12f8ec7f4aaa8d62578dba5b3b8db9c2 460 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 297 325 - T 14-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 Tharo_1101 d25f38b1969c06d2b59a1383fbfbbd59 304 Pfam PF04909 Amidohydrolase 28 299 4.1E-51 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Tharo_1101 d25f38b1969c06d2b59a1383fbfbbd59 304 Gene3D G3DSA:3.20.20.140 7 303 1.6E-85 T 14-10-2018 Tharo_1101 d25f38b1969c06d2b59a1383fbfbbd59 304 SUPERFAMILY SSF51556 23 299 4.38E-78 T 14-10-2018 IPR032466 Metal-dependent hydrolase Tharo_2306 f51faa3a3f2a372010fded2d4d3e62ad 689 SUPERFAMILY SSF54980 587 673 2.4E-12 T 14-10-2018 IPR035647 EF-G domain III/V-like Tharo_2306 f51faa3a3f2a372010fded2d4d3e62ad 689 SMART SM00838 584 672 1.5E-7 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like Tharo_2306 f51faa3a3f2a372010fded2d4d3e62ad 689 SMART SM00889 464 582 1.7E-56 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Tharo_2306 f51faa3a3f2a372010fded2d4d3e62ad 689 SUPERFAMILY SSF52540 6 260 1.61E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2306 f51faa3a3f2a372010fded2d4d3e62ad 689 Pfam PF00679 Elongation factor G C-terminus 585 671 5.2E-16 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like Tharo_2306 f51faa3a3f2a372010fded2d4d3e62ad 689 Gene3D G3DSA:3.40.50.300 10 366 1.8E-71 T 14-10-2018 Tharo_2306 f51faa3a3f2a372010fded2d4d3e62ad 689 Gene3D G3DSA:3.30.70.240 588 659 2.8E-64 T 14-10-2018 Tharo_2306 f51faa3a3f2a372010fded2d4d3e62ad 689 Pfam PF14492 Elongation Factor G, domain II 389 460 1.2E-17 T 14-10-2018 Tharo_2306 f51faa3a3f2a372010fded2d4d3e62ad 689 SUPERFAMILY SSF54211 463 583 1.67E-38 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_2306 f51faa3a3f2a372010fded2d4d3e62ad 689 SUPERFAMILY SSF54980 388 466 9.35E-16 T 14-10-2018 IPR035647 EF-G domain III/V-like Tharo_2306 f51faa3a3f2a372010fded2d4d3e62ad 689 Pfam PF03764 Elongation factor G, domain IV 463 582 2.9E-38 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Tharo_2306 f51faa3a3f2a372010fded2d4d3e62ad 689 SUPERFAMILY SSF50447 245 378 2.69E-22 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Tharo_2306 f51faa3a3f2a372010fded2d4d3e62ad 689 Gene3D G3DSA:3.40.50.300 17 258 1.8E-71 T 14-10-2018 Tharo_2306 f51faa3a3f2a372010fded2d4d3e62ad 689 Gene3D G3DSA:3.30.70.870 389 467 2.7E-19 T 14-10-2018 Tharo_2306 f51faa3a3f2a372010fded2d4d3e62ad 689 Pfam PF00009 Elongation factor Tu GTP binding domain 8 260 8.1E-29 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2306 f51faa3a3f2a372010fded2d4d3e62ad 689 Gene3D G3DSA:3.30.230.10 468 671 2.8E-64 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Tharo_1022 ed808e531a5a684f6b2351075c849ec5 608 SUPERFAMILY SSF116726 212 293 6.8E-13 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Tharo_1022 ed808e531a5a684f6b2351075c849ec5 608 Pfam PF02080 TrkA-C domain 223 281 6.6E-7 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Tharo_1022 ed808e531a5a684f6b2351075c849ec5 608 Pfam PF02080 TrkA-C domain 329 398 3.8E-11 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Tharo_1022 ed808e531a5a684f6b2351075c849ec5 608 Gene3D G3DSA:3.30.70.1450 325 399 5.6E-14 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Tharo_1022 ed808e531a5a684f6b2351075c849ec5 608 Gene3D G3DSA:3.30.70.1450 214 289 4.6E-9 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Tharo_1022 ed808e531a5a684f6b2351075c849ec5 608 Pfam PF03600 Citrate transporter 17 555 5.3E-48 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 Tharo_1022 ed808e531a5a684f6b2351075c849ec5 608 SUPERFAMILY SSF116726 319 404 4.97E-17 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Tharo_0145 17ae7d6b82bb115cc17768116874cf2b 241 PIRSF PIRSF016262 29 237 8.0E-57 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Tharo_0145 17ae7d6b82bb115cc17768116874cf2b 241 Gene3D G3DSA:3.30.930.10 25 228 4.5E-63 T 14-10-2018 Tharo_0145 17ae7d6b82bb115cc17768116874cf2b 241 Hamap MF_00013 Octanoyltransferase [lipB]. 29 231 37.361 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Tharo_0145 17ae7d6b82bb115cc17768116874cf2b 241 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 96 111 - T 14-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 Tharo_0145 17ae7d6b82bb115cc17768116874cf2b 241 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 100 153 5.0E-18 T 14-10-2018 Tharo_0145 17ae7d6b82bb115cc17768116874cf2b 241 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 51 228 1.8E-60 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Tharo_0145 17ae7d6b82bb115cc17768116874cf2b 241 Pfam PF03099 Biotin/lipoate A/B protein ligase family 86 184 2.6E-9 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 Tharo_0145 17ae7d6b82bb115cc17768116874cf2b 241 SUPERFAMILY SSF55681 28 229 1.57E-66 T 14-10-2018 Tharo_3283 44d267382345f5d7a8bd1345911c7684 353 SUPERFAMILY SSF56042 174 349 1.94E-47 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Tharo_3283 44d267382345f5d7a8bd1345911c7684 353 Pfam PF00586 AIR synthase related protein, N-terminal domain 51 164 6.7E-18 T 14-10-2018 IPR016188 PurM-like, N-terminal domain Tharo_3283 44d267382345f5d7a8bd1345911c7684 353 Gene3D G3DSA:3.30.1330.10 22 168 1.7E-52 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Tharo_3283 44d267382345f5d7a8bd1345911c7684 353 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 18 353 1.1E-134 T 14-10-2018 IPR011854 Carbamoyl dehydratase HypE Tharo_3283 44d267382345f5d7a8bd1345911c7684 353 PIRSF PIRSF005644 14 353 1.5E-122 T 14-10-2018 IPR011854 Carbamoyl dehydratase HypE Tharo_3283 44d267382345f5d7a8bd1345911c7684 353 Pfam PF02769 AIR synthase related protein, C-terminal domain 177 330 1.9E-27 T 14-10-2018 IPR010918 PurM-like, C-terminal domain Tharo_3283 44d267382345f5d7a8bd1345911c7684 353 SUPERFAMILY SSF55326 24 167 7.5E-34 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Tharo_3283 44d267382345f5d7a8bd1345911c7684 353 Gene3D G3DSA:3.90.650.10 172 353 3.4E-55 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Tharo_3145 354a0f0d5989f43fb3be008150333cba 551 SMART SM01080 67 425 4.4E-10 T 14-10-2018 IPR007890 CHASE2 Tharo_3145 354a0f0d5989f43fb3be008150333cba 551 Pfam PF05226 CHASE2 domain 83 417 7.6E-17 T 14-10-2018 IPR007890 CHASE2 Tharo_2682 09b400174c1322c7b1ebd0769fdcd006 293 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 14-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 Tharo_2682 09b400174c1322c7b1ebd0769fdcd006 293 SUPERFAMILY SSF48179 162 286 1.81E-37 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Tharo_2682 09b400174c1322c7b1ebd0769fdcd006 293 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 284 1.0E-35 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 Tharo_2682 09b400174c1322c7b1ebd0769fdcd006 293 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 161 1.1E-47 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 Tharo_2682 09b400174c1322c7b1ebd0769fdcd006 293 PIRSF PIRSF000103 1 293 1.6E-78 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 Tharo_2682 09b400174c1322c7b1ebd0769fdcd006 293 SUPERFAMILY SSF51735 1 162 1.01E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_2682 09b400174c1322c7b1ebd0769fdcd006 293 Gene3D G3DSA:1.10.1040.10 162 291 5.4E-38 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Tharo_2682 09b400174c1322c7b1ebd0769fdcd006 293 Gene3D G3DSA:3.40.50.720 1 161 2.2E-51 T 14-10-2018 Tharo_2187 6dca5a28190079ec6ee637e8ce3caea3 538 Gene3D G3DSA:3.20.20.80 98 292 2.1E-12 T 14-10-2018 Tharo_2187 6dca5a28190079ec6ee637e8ce3caea3 538 SUPERFAMILY SSF51445 50 317 4.38E-51 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily Tharo_0774 02ba80c669e4c2d38cad91af0ed5b15b 526 Hamap MF_00703 Putative thymidine phosphorylase. 19 516 59.6 T 14-10-2018 IPR028579 Putative thymidine phosphorylase KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181 Tharo_0774 02ba80c669e4c2d38cad91af0ed5b15b 526 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 214 229 - T 14-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0774 02ba80c669e4c2d38cad91af0ed5b15b 526 SUPERFAMILY SSF54680 432 521 9.16E-16 T 14-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0774 02ba80c669e4c2d38cad91af0ed5b15b 526 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 18 512 1.5E-182 T 14-10-2018 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 Tharo_0774 02ba80c669e4c2d38cad91af0ed5b15b 526 Gene3D G3DSA:3.40.1030.10 171 422 1.2E-102 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0774 02ba80c669e4c2d38cad91af0ed5b15b 526 Pfam PF02885 Glycosyl transferase family, helical bundle domain 111 169 1.3E-5 T 14-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0774 02ba80c669e4c2d38cad91af0ed5b15b 526 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 446 511 1.9E-9 T 14-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0774 02ba80c669e4c2d38cad91af0ed5b15b 526 Pfam PF00591 Glycosyl transferase family, a/b domain 180 243 2.6E-6 T 14-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0774 02ba80c669e4c2d38cad91af0ed5b15b 526 SUPERFAMILY SSF52418 173 422 7.06E-67 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0774 02ba80c669e4c2d38cad91af0ed5b15b 526 SMART SM00941 445 512 3.0E-19 T 14-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0774 02ba80c669e4c2d38cad91af0ed5b15b 526 Gene3D G3DSA:1.20.970.50 113 345 1.2E-102 T 14-10-2018 Tharo_0774 02ba80c669e4c2d38cad91af0ed5b15b 526 Gene3D G3DSA:3.90.1170.30 435 513 3.5E-18 T 14-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0774 02ba80c669e4c2d38cad91af0ed5b15b 526 PIRSF PIRSF000478 105 525 2.6E-120 T 14-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0774 02ba80c669e4c2d38cad91af0ed5b15b 526 SUPERFAMILY SSF47648 108 174 5.23E-10 T 14-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 763 822 3.3E-29 T 14-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 45 179 2.4E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 Gene3D G3DSA:3.40.50.670 435 606 2.0E-74 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 ProSitePatterns PS00177 DNA topoisomerase II signature. 459 467 - T 14-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 SUPERFAMILY SSF54211 249 429 3.6E-55 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 SUPERFAMILY SSF56719 431 823 7.59E-87 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 15 833 96.887 T 14-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 SUPERFAMILY SSF55874 18 244 2.36E-64 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 Pfam PF00204 DNA gyrase B 249 427 6.9E-58 T 14-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 Gene3D G3DSA:3.30.230.10 249 429 7.9E-69 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 PRINTS PR01159 DNA gyrase subunit B signature 507 516 1.1E-78 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 PRINTS PR01159 DNA gyrase subunit B signature 209 224 1.1E-78 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 PRINTS PR01159 DNA gyrase subunit B signature 397 411 1.1E-78 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 PRINTS PR01159 DNA gyrase subunit B signature 411 431 1.1E-78 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 PRINTS PR01159 DNA gyrase subunit B signature 802 818 1.1E-78 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 PRINTS PR01159 DNA gyrase subunit B signature 18 28 1.1E-78 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 PRINTS PR01159 DNA gyrase subunit B signature 224 237 1.1E-78 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 PRINTS PR01159 DNA gyrase subunit B signature 279 297 1.1E-78 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 PRINTS PR01159 DNA gyrase subunit B signature 248 270 1.1E-78 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 PRINTS PR01159 DNA gyrase subunit B signature 349 365 1.1E-78 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 PRINTS PR01159 DNA gyrase subunit B signature 786 798 1.1E-78 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 SMART SM00387 44 204 2.4E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 Pfam PF01751 Toprim domain 456 568 7.1E-19 T 14-10-2018 IPR006171 TOPRIM domain Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 SMART SM00433 48 826 2.8E-254 T 14-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 Gene3D G3DSA:3.30.565.10 14 248 3.8E-88 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 18 833 2.3E-287 T 14-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 PRINTS PR00418 DNA topoisomerase II family signature 765 781 4.5E-68 T 14-10-2018 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 PRINTS PR00418 DNA topoisomerase II family signature 457 471 4.5E-68 T 14-10-2018 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 PRINTS PR00418 DNA topoisomerase II family signature 83 96 4.5E-68 T 14-10-2018 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 PRINTS PR00418 DNA topoisomerase II family signature 305 318 4.5E-68 T 14-10-2018 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 PRINTS PR00418 DNA topoisomerase II family signature 562 574 4.5E-68 T 14-10-2018 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 PRINTS PR00418 DNA topoisomerase II family signature 524 540 4.5E-68 T 14-10-2018 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 PRINTS PR00418 DNA topoisomerase II family signature 130 144 4.5E-68 T 14-10-2018 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 PRINTS PR00418 DNA topoisomerase II family signature 48 63 4.5E-68 T 14-10-2018 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 PRINTS PR00418 DNA topoisomerase II family signature 542 559 4.5E-68 T 14-10-2018 Tharo_0003 f199bd36fce97a9ec7089cc7a0822fb8 833 Gene3D G3DSA:3.40.50.670 719 832 8.0E-25 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Tharo_0646 643478108a37c7f4f35f4f01c99faf02 276 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 1 238 16.49 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Tharo_0646 643478108a37c7f4f35f4f01c99faf02 276 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 8 35 2.8E-45 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Tharo_0646 643478108a37c7f4f35f4f01c99faf02 276 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 85 103 2.8E-45 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Tharo_0646 643478108a37c7f4f35f4f01c99faf02 276 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 103 129 2.8E-45 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Tharo_0646 643478108a37c7f4f35f4f01c99faf02 276 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 154 182 2.8E-45 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Tharo_0646 643478108a37c7f4f35f4f01c99faf02 276 Pfam PF00902 Sec-independent protein translocase protein (TatC) 12 221 1.3E-67 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Tharo_0646 643478108a37c7f4f35f4f01c99faf02 276 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 10 226 9.7E-70 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Tharo_3076 7288d6da3eb2bb3305a5078aeec20937 194 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 120 165 4.0E-13 T 14-10-2018 IPR022453 Zinc finger, MqsA-type Tharo_3076 7288d6da3eb2bb3305a5078aeec20937 194 Pfam PF14076 Domain of unknown function (DUF4258) 24 90 1.3E-9 T 14-10-2018 IPR025354 Protein of unknown function DUF4258 Tharo_2722 359435170d5d30e1e0f9331c0478837d 101 SUPERFAMILY SSF54189 5 95 1.47E-29 T 14-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2722 359435170d5d30e1e0f9331c0478837d 101 Gene3D G3DSA:3.30.70.330 3 101 9.9E-35 T 14-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily Tharo_2722 359435170d5d30e1e0f9331c0478837d 101 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 10 100 22.199 T 14-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 Tharo_2722 359435170d5d30e1e0f9331c0478837d 101 Pfam PF00276 Ribosomal protein L23 11 97 1.7E-30 T 14-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 337 351 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 SUPERFAMILY SSF100920 384 540 5.49E-63 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 Gene3D G3DSA:1.20.1270.10 524 607 5.5E-27 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 603 3.4E-297 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 192 205 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 PRINTS PR00301 70kDa heat shock protein signature 334 350 2.3E-78 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.3E-78 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 PRINTS PR00301 70kDa heat shock protein signature 388 407 2.3E-78 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 PRINTS PR00301 70kDa heat shock protein signature 469 485 2.3E-78 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 PRINTS PR00301 70kDa heat shock protein signature 365 385 2.3E-78 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 PRINTS PR00301 70kDa heat shock protein signature 138 158 2.3E-78 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 PRINTS PR00301 70kDa heat shock protein signature 198 208 2.3E-78 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.3E-78 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.3E-78 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 Pfam PF00012 Hsp70 protein 4 603 1.3E-266 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 SUPERFAMILY SSF53067 187 382 1.15E-67 T 14-10-2018 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 Gene3D G3DSA:3.30.420.40 180 366 2.6E-165 T 14-10-2018 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 SUPERFAMILY SSF53067 4 184 9.39E-64 T 14-10-2018 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 634 37.357 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 Gene3D G3DSA:2.60.34.10 383 523 1.9E-66 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 SUPERFAMILY SSF100934 507 604 1.16E-20 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 Gene3D G3DSA:3.30.420.40 5 379 2.6E-165 T 14-10-2018 Tharo_1203 f296ace3f5f1c53f0f65eb99a6b7792e 638 Gene3D G3DSA:3.90.640.10 229 316 2.6E-165 T 14-10-2018 Tharo_3169 9aaa84a0a1866628d3246e5450d45ae2 511 Gene3D G3DSA:3.10.450.50 80 120 2.0E-7 T 14-10-2018 Tharo_3169 9aaa84a0a1866628d3246e5450d45ae2 511 SUPERFAMILY SSF103642 99 119 3.76E-7 T 14-10-2018 Tharo_3169 9aaa84a0a1866628d3246e5450d45ae2 511 SUPERFAMILY SSF159941 330 495 1.02E-50 T 14-10-2018 IPR024047 MM3350-like superfamily Tharo_3169 9aaa84a0a1866628d3246e5450d45ae2 511 Pfam PF07929 Plasmid pRiA4b ORF-3-like protein 332 496 9.6E-55 T 14-10-2018 IPR012912 Plasmid pRiA4b, Orf3 Tharo_3169 9aaa84a0a1866628d3246e5450d45ae2 511 Gene3D G3DSA:3.10.290.30 326 500 5.5E-54 T 14-10-2018 IPR024047 MM3350-like superfamily Tharo_3169 9aaa84a0a1866628d3246e5450d45ae2 511 Pfam PF02810 SEC-C motif 101 118 1.3E-9 T 14-10-2018 IPR004027 SEC-C motif Tharo_1813 b25f58a6b36d881996feb6fe764541e7 387 Gene3D G3DSA:3.40.50.2300 25 350 9.6E-89 T 14-10-2018 Tharo_1813 b25f58a6b36d881996feb6fe764541e7 387 SUPERFAMILY SSF53822 24 381 7.59E-77 T 14-10-2018 IPR028082 Periplasmic binding protein-like I Tharo_1813 b25f58a6b36d881996feb6fe764541e7 387 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 328 343 4.5E-5 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Tharo_1813 b25f58a6b36d881996feb6fe764541e7 387 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 25 41 4.5E-5 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Tharo_1813 b25f58a6b36d881996feb6fe764541e7 387 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 273 286 4.5E-5 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Tharo_1813 b25f58a6b36d881996feb6fe764541e7 387 Pfam PF13458 Periplasmic binding protein 24 360 3.1E-65 T 14-10-2018 IPR028081 Leucine-binding protein domain Tharo_1813 b25f58a6b36d881996feb6fe764541e7 387 Gene3D G3DSA:3.40.50.2300 142 360 9.6E-89 T 14-10-2018 Tharo_2889 8d960d896149664246ee45b27a81efa8 147 Pfam PF14090 Helix-turn-helix domain 45 110 3.1E-8 T 14-10-2018 Tharo_0302 31fbc9974adffd38394da942de8d020f 961 TIGRFAM TIGR03744 traC_PFL_4706: conjugative transfer ATPase, PFL_4706 family 54 951 0.0 T 14-10-2018 IPR022303 Conjugative transfer ATPase Tharo_0302 31fbc9974adffd38394da942de8d020f 961 SUPERFAMILY SSF52540 482 902 8.27E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0302 31fbc9974adffd38394da942de8d020f 961 Pfam PF11130 F pilus assembly Type-IV secretion system for plasmid transfer 65 339 1.0E-72 T 14-10-2018 IPR025955 Type-IV secretion system protein TraC/Conjugative transfer ATPase Tharo_2352 3da8370e13ebeef94fb82fb77843d1d9 510 SUPERFAMILY SSF55154 1 214 6.21E-41 T 14-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 Tharo_2352 3da8370e13ebeef94fb82fb77843d1d9 510 Gene3D G3DSA:1.40.20.10 215 503 3.7E-49 T 14-10-2018 IPR038186 CHAD domain superfamily Tharo_2352 3da8370e13ebeef94fb82fb77843d1d9 510 Pfam PF01928 CYTH domain 4 200 9.5E-29 T 14-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 Tharo_2352 3da8370e13ebeef94fb82fb77843d1d9 510 Pfam PF05235 CHAD domain 234 464 1.1E-39 T 14-10-2018 IPR007899 CHAD domain Tharo_2352 3da8370e13ebeef94fb82fb77843d1d9 510 SMART SM01118 2 206 5.2E-35 T 14-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 Tharo_2352 3da8370e13ebeef94fb82fb77843d1d9 510 SMART SM00880 232 499 1.8E-46 T 14-10-2018 IPR007899 CHAD domain Tharo_2352 3da8370e13ebeef94fb82fb77843d1d9 510 Gene3D G3DSA:2.40.320.10 1 202 1.5E-29 T 14-10-2018 Tharo_0914 7d31c495ccd1826de8dbc0299dd5f61e 527 Pfam PF00672 HAMP domain 97 139 5.9E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_0914 7d31c495ccd1826de8dbc0299dd5f61e 527 Gene3D G3DSA:3.30.450.20 390 522 7.0E-15 T 14-10-2018 Tharo_0914 7d31c495ccd1826de8dbc0299dd5f61e 527 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 209 359 3.7E-45 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_0914 7d31c495ccd1826de8dbc0299dd5f61e 527 SMART SM00283 144 391 1.1E-72 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_0914 7d31c495ccd1826de8dbc0299dd5f61e 527 SUPERFAMILY SSF58104 111 396 2.88E-64 T 14-10-2018 Tharo_0914 7d31c495ccd1826de8dbc0299dd5f61e 527 Gene3D G3DSA:1.10.287.950 94 389 5.8E-76 T 14-10-2018 Tharo_0914 7d31c495ccd1826de8dbc0299dd5f61e 527 SMART SM00304 91 143 1.4E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_0914 7d31c495ccd1826de8dbc0299dd5f61e 527 Pfam PF17200 Single Cache domain 2 427 520 4.2E-8 T 14-10-2018 IPR033480 Single Cache domain 2 Tharo_3127 109c1aca8650726040885ce4c9d26c40 1282 Gene3D G3DSA:3.20.20.220 48 141 1.8E-12 T 14-10-2018 Tharo_3127 109c1aca8650726040885ce4c9d26c40 1282 Gene3D G3DSA:3.20.20.220 184 561 1.8E-141 T 14-10-2018 Tharo_3127 109c1aca8650726040885ce4c9d26c40 1282 Gene3D G3DSA:3.40.309.10 851 1043 2.2E-141 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Tharo_3127 109c1aca8650726040885ce4c9d26c40 1282 Gene3D G3DSA:3.40.605.10 633 1071 2.2E-141 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Tharo_3127 109c1aca8650726040885ce4c9d26c40 1282 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 562 1072 1.7E-205 T 14-10-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 Tharo_3127 109c1aca8650726040885ce4c9d26c40 1282 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 876 887 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 Tharo_3127 109c1aca8650726040885ce4c9d26c40 1282 Pfam PF00171 Aldehyde dehydrogenase family 633 1069 5.8E-114 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Tharo_3127 109c1aca8650726040885ce4c9d26c40 1282 PIRSF PIRSF000197 35 1281 0.0 T 14-10-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 Tharo_3127 109c1aca8650726040885ce4c9d26c40 1282 SUPERFAMILY SSF53720 629 1071 7.59E-122 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Tharo_3127 109c1aca8650726040885ce4c9d26c40 1282 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 105 216 4.3E-42 T 14-10-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 Tharo_3127 109c1aca8650726040885ce4c9d26c40 1282 SUPERFAMILY SSF51730 219 569 1.1E-116 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like Tharo_3127 109c1aca8650726040885ce4c9d26c40 1282 Pfam PF01619 Proline dehydrogenase 233 526 2.0E-97 T 14-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 Tharo_3127 109c1aca8650726040885ce4c9d26c40 1282 SUPERFAMILY SSF81935 49 218 1.06E-58 T 14-10-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 Tharo_2161 8b4708507f93d710863853456175e138 256 SUPERFAMILY SSF53335 12 229 7.47E-38 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_2161 8b4708507f93d710863853456175e138 256 Pfam PF01564 Spermine/spermidine synthase domain 60 168 1.1E-8 T 14-10-2018 Tharo_2161 8b4708507f93d710863853456175e138 256 Gene3D G3DSA:3.40.50.150 6 246 1.6E-42 T 14-10-2018 Tharo_0001 6deb7e7cf43f3f7016b3e111773d196c 513 Gene3D G3DSA:3.30.300.180 14 112 1.8E-23 T 14-10-2018 IPR038454 DnaA, N-terminal domain superfamily Tharo_0001 6deb7e7cf43f3f7016b3e111773d196c 513 SUPERFAMILY SSF48295 409 512 8.37E-37 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 Tharo_0001 6deb7e7cf43f3f7016b3e111773d196c 513 Pfam PF00308 Bacterial dnaA protein 178 395 1.7E-87 T 14-10-2018 IPR013317 Chromosomal replication initiator protein DnaA Tharo_0001 6deb7e7cf43f3f7016b3e111773d196c 513 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 275 289 1.1E-46 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like Tharo_0001 6deb7e7cf43f3f7016b3e111773d196c 513 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 211 231 1.1E-46 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like Tharo_0001 6deb7e7cf43f3f7016b3e111773d196c 513 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 309 336 1.1E-46 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like Tharo_0001 6deb7e7cf43f3f7016b3e111773d196c 513 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 471 490 1.1E-46 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like Tharo_0001 6deb7e7cf43f3f7016b3e111773d196c 513 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 243 257 1.1E-46 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like Tharo_0001 6deb7e7cf43f3f7016b3e111773d196c 513 Gene3D G3DSA:1.10.8.60 344 413 2.3E-23 T 14-10-2018 Tharo_0001 6deb7e7cf43f3f7016b3e111773d196c 513 Pfam PF11638 DnaA N-terminal domain 15 74 2.4E-17 T 14-10-2018 IPR024633 DnaA N-terminal domain Tharo_0001 6deb7e7cf43f3f7016b3e111773d196c 513 Gene3D G3DSA:3.40.50.300 168 342 8.0E-48 T 14-10-2018 Tharo_0001 6deb7e7cf43f3f7016b3e111773d196c 513 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 17 510 1.2E-173 T 14-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 Tharo_0001 6deb7e7cf43f3f7016b3e111773d196c 513 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 14 512 32.199 T 14-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 Tharo_0001 6deb7e7cf43f3f7016b3e111773d196c 513 Gene3D G3DSA:1.10.1750.10 414 512 1.5E-34 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 Tharo_0001 6deb7e7cf43f3f7016b3e111773d196c 513 SUPERFAMILY SSF52540 177 390 4.55E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0001 6deb7e7cf43f3f7016b3e111773d196c 513 SMART SM00760 421 490 1.2E-43 T 14-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 Tharo_0001 6deb7e7cf43f3f7016b3e111773d196c 513 ProSitePatterns PS01008 DnaA protein signature. 471 490 - T 14-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 Tharo_0001 6deb7e7cf43f3f7016b3e111773d196c 513 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 422 490 6.1E-32 T 14-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 Tharo_0001 6deb7e7cf43f3f7016b3e111773d196c 513 SMART SM00382 210 341 2.9E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_3080 2a2ed152042f70971d51087677c6181d 83 SUPERFAMILY SSF143120 1 80 1.31E-24 T 14-10-2018 IPR036165 YefM-like superfamily Tharo_3080 2a2ed152042f70971d51087677c6181d 83 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 74 7.2E-24 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Tharo_3080 2a2ed152042f70971d51087677c6181d 83 Gene3D G3DSA:1.10.1220.170 41 83 8.6E-17 T 14-10-2018 Tharo_3080 2a2ed152042f70971d51087677c6181d 83 Gene3D G3DSA:3.40.1620.10 1 40 3.8E-17 T 14-10-2018 Tharo_3080 2a2ed152042f70971d51087677c6181d 83 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 56 1.4E-10 T 14-10-2018 Tharo_2792 9623c10543614b9c48809141f9b5848c 663 Pfam PF00364 Biotin-requiring enzyme 599 661 3.7E-16 T 14-10-2018 IPR000089 Biotin/lipoyl attachment Tharo_2792 9623c10543614b9c48809141f9b5848c 663 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Tharo_2792 9623c10543614b9c48809141f9b5848c 663 Gene3D G3DSA:2.40.50.100 591 663 2.0E-20 T 14-10-2018 Tharo_2792 9623c10543614b9c48809141f9b5848c 663 Gene3D G3DSA:3.30.700.30 452 583 4.8E-29 T 14-10-2018 Tharo_2792 9623c10543614b9c48809141f9b5848c 663 Pfam PF02785 Biotin carboxylase C-terminal domain 337 445 4.5E-39 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Tharo_2792 9623c10543614b9c48809141f9b5848c 663 SUPERFAMILY SSF51246 332 448 1.36E-42 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 Tharo_2792 9623c10543614b9c48809141f9b5848c 663 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Tharo_2792 9623c10543614b9c48809141f9b5848c 663 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 446 1.1E-190 T 14-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 Tharo_2792 9623c10543614b9c48809141f9b5848c 663 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 619 636 - T 14-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Tharo_2792 9623c10543614b9c48809141f9b5848c 663 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 107 1.4E-44 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Tharo_2792 9623c10543614b9c48809141f9b5848c 663 Gene3D G3DSA:3.30.470.130 1 450 2.8E-199 T 14-10-2018 Tharo_2792 9623c10543614b9c48809141f9b5848c 663 SUPERFAMILY SSF51230 585 663 4.84E-19 T 14-10-2018 IPR011053 Single hybrid motif Tharo_2792 9623c10543614b9c48809141f9b5848c 663 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 324 4.1E-78 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Tharo_2792 9623c10543614b9c48809141f9b5848c 663 SUPERFAMILY SSF56059 83 349 9.02E-68 T 14-10-2018 Tharo_2792 9623c10543614b9c48809141f9b5848c 663 SMART SM00878 337 445 6.4E-64 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Tharo_2792 9623c10543614b9c48809141f9b5848c 663 SUPERFAMILY SSF52440 1 112 7.19E-47 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Tharo_1280 f2442756eb4e00b3e8b188f5b18e8f03 242 Gene3D G3DSA:3.40.50.2300 3 132 2.4E-33 T 14-10-2018 Tharo_1280 f2442756eb4e00b3e8b188f5b18e8f03 242 Gene3D G3DSA:1.10.10.10 133 241 5.3E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1280 f2442756eb4e00b3e8b188f5b18e8f03 242 SUPERFAMILY SSF52172 6 126 2.13E-35 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1280 f2442756eb4e00b3e8b188f5b18e8f03 242 SUPERFAMILY SSF46894 135 238 8.79E-26 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_1280 f2442756eb4e00b3e8b188f5b18e8f03 242 Pfam PF00486 Transcriptional regulatory protein, C terminal 165 237 4.6E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_1280 f2442756eb4e00b3e8b188f5b18e8f03 242 SMART SM00862 161 237 9.6E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_1280 f2442756eb4e00b3e8b188f5b18e8f03 242 SMART SM00448 9 119 2.7E-36 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1280 f2442756eb4e00b3e8b188f5b18e8f03 242 Pfam PF00072 Response regulator receiver domain 11 118 7.8E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_3023 59d8428608ee273cbb72aa64bca3c48a 346 Gene3D G3DSA:1.20.120.920 86 345 2.9E-75 T 14-10-2018 Tharo_3023 59d8428608ee273cbb72aa64bca3c48a 346 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 331 27.637 T 14-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 Tharo_3023 59d8428608ee273cbb72aa64bca3c48a 346 Gene3D G3DSA:3.100.10.20 6 84 5.1E-19 T 14-10-2018 Tharo_3023 59d8428608ee273cbb72aa64bca3c48a 346 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 7 341 2.3E-83 T 14-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 Tharo_3023 59d8428608ee273cbb72aa64bca3c48a 346 TIGRFAM TIGR03640 cas1_DVULG: CRISPR-associated endonuclease Cas1, subtype I-C/DVULG 4 345 1.7E-155 T 14-10-2018 IPR019856 CRISPR-associated protein Cas1, DVULG subtype GO:0004520|GO:0043571|GO:0046872 Tharo_3023 59d8428608ee273cbb72aa64bca3c48a 346 Pfam PF01867 CRISPR associated protein Cas1 8 301 1.8E-105 T 14-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 Tharo_1324 8648d48c930777476cd9f1abdbd079c1 181 SUPERFAMILY SSF52499 2 177 2.09E-45 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 Tharo_1324 8648d48c930777476cd9f1abdbd079c1 181 Pfam PF00857 Isochorismatase family 9 157 5.3E-24 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 Tharo_1324 8648d48c930777476cd9f1abdbd079c1 181 Gene3D G3DSA:3.40.50.850 1 180 3.7E-47 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 Tharo_2579 39f1d173889e9a8092ad40a59ecef629 341 SUPERFAMILY SSF48576 23 340 2.88E-98 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily Tharo_2579 39f1d173889e9a8092ad40a59ecef629 341 Pfam PF00348 Polyprenyl synthetase 50 280 2.9E-74 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 Tharo_2579 39f1d173889e9a8092ad40a59ecef629 341 Gene3D G3DSA:1.10.600.10 7 341 1.0E-111 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily Tharo_2579 39f1d173889e9a8092ad40a59ecef629 341 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 100 114 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site Tharo_2579 39f1d173889e9a8092ad40a59ecef629 341 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 222 234 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site Tharo_2295 de2b05524f77bc5379a51bff2148adb9 296 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 37 295 4.1E-85 T 14-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III Tharo_2295 de2b05524f77bc5379a51bff2148adb9 296 PIRSF PIRSF000006 5 296 1.1E-94 T 14-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III Tharo_2295 de2b05524f77bc5379a51bff2148adb9 296 SUPERFAMILY SSF46626 59 208 2.04E-31 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_2295 de2b05524f77bc5379a51bff2148adb9 296 Gene3D G3DSA:1.10.760.10 183 270 1.1E-75 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_2295 de2b05524f77bc5379a51bff2148adb9 296 Gene3D G3DSA:1.10.760.10 104 293 1.1E-75 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_2295 de2b05524f77bc5379a51bff2148adb9 296 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 215 290 2.0E-13 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_2295 de2b05524f77bc5379a51bff2148adb9 296 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 128 202 4.1E-13 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_2295 de2b05524f77bc5379a51bff2148adb9 296 PRINTS PR00605 Class IC cytochrome C signature 224 235 2.0E-5 T 14-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 Tharo_2295 de2b05524f77bc5379a51bff2148adb9 296 PRINTS PR00605 Class IC cytochrome C signature 268 290 2.0E-5 T 14-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 Tharo_2295 de2b05524f77bc5379a51bff2148adb9 296 SUPERFAMILY SSF46626 214 293 3.49E-25 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_2295 de2b05524f77bc5379a51bff2148adb9 296 Gene3D G3DSA:1.20.58.1490 5 98 3.1E-28 T 14-10-2018 IPR038414 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal domain superfamily Tharo_2295 de2b05524f77bc5379a51bff2148adb9 296 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 41 84 1.1E-21 T 14-10-2018 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal Tharo_0559 379266ca52fd93aaa49d899e99ffec85 162 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 4 160 35.51 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Tharo_0559 379266ca52fd93aaa49d899e99ffec85 162 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 64 9.2E-16 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Tharo_0559 379266ca52fd93aaa49d899e99ffec85 162 Pfam PF01467 Cytidylyltransferase-like 7 135 1.7E-20 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Tharo_0559 379266ca52fd93aaa49d899e99ffec85 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 22 43 4.2E-48 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Tharo_0559 379266ca52fd93aaa49d899e99ffec85 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 4 22 4.2E-48 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Tharo_0559 379266ca52fd93aaa49d899e99ffec85 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 114 136 4.2E-48 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Tharo_0559 379266ca52fd93aaa49d899e99ffec85 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 87 103 4.2E-48 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Tharo_0559 379266ca52fd93aaa49d899e99ffec85 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 51 75 4.2E-48 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Tharo_0559 379266ca52fd93aaa49d899e99ffec85 162 Gene3D G3DSA:3.40.50.620 1 162 4.0E-55 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_0559 379266ca52fd93aaa49d899e99ffec85 162 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 5 158 1.3E-58 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Tharo_0559 379266ca52fd93aaa49d899e99ffec85 162 SUPERFAMILY SSF52374 4 157 2.18E-43 T 14-10-2018 Tharo_1504 1c3e9c431b62a775101eb5728844af63 334 Gene3D G3DSA:1.10.8.1150 35 109 8.0E-6 T 14-10-2018 Tharo_1504 1c3e9c431b62a775101eb5728844af63 334 Pfam PF02618 YceG-like family 40 325 1.2E-80 T 14-10-2018 IPR003770 Endolytic murein transglycosylase Tharo_1504 1c3e9c431b62a775101eb5728844af63 334 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 9 330 34.132 T 14-10-2018 IPR003770 Endolytic murein transglycosylase Tharo_1504 1c3e9c431b62a775101eb5728844af63 334 Gene3D G3DSA:3.30.160.60 299 333 1.8E-9 T 14-10-2018 Tharo_1504 1c3e9c431b62a775101eb5728844af63 334 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 8 330 8.9E-83 T 14-10-2018 IPR003770 Endolytic murein transglycosylase Tharo_0068 cf361646cf341d893abc1b4a83baed99 498 Gene3D G3DSA:1.10.10.10 414 496 2.5E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0068 cf361646cf341d893abc1b4a83baed99 498 Gene3D G3DSA:3.30.950.30 2 131 2.6E-23 T 14-10-2018 IPR038461 Schlafen, AAA domain superfamily Tharo_0068 cf361646cf341d893abc1b4a83baed99 498 Gene3D G3DSA:3.30.565.60 236 389 8.7E-14 T 14-10-2018 IPR038475 RecG, C-terminal domain superfamily Tharo_0068 cf361646cf341d893abc1b4a83baed99 498 Pfam PF04326 Putative DNA-binding domain 14 124 3.6E-17 T 14-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 Tharo_0068 cf361646cf341d893abc1b4a83baed99 498 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 332 386 2.8E-6 T 14-10-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain Tharo_0068 cf361646cf341d893abc1b4a83baed99 498 SUPERFAMILY SSF46785 427 494 2.18E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0554 8cf528a9aa2d323bcc33a027bf28917c 292 Gene3D G3DSA:3.30.70.890 175 291 2.6E-34 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily Tharo_0554 8cf528a9aa2d323bcc33a027bf28917c 292 SUPERFAMILY SSF54211 21 172 1.06E-41 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_0554 8cf528a9aa2d323bcc33a027bf28917c 292 Gene3D G3DSA:3.30.230.10 9 172 5.3E-51 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Tharo_0554 8cf528a9aa2d323bcc33a027bf28917c 292 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 21 287 1.5E-76 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 Tharo_0554 8cf528a9aa2d323bcc33a027bf28917c 292 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 18 279 32.228 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 Tharo_0554 8cf528a9aa2d323bcc33a027bf28917c 292 Pfam PF00288 GHMP kinases N terminal domain 101 157 3.7E-8 T 14-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 Tharo_0554 8cf528a9aa2d323bcc33a027bf28917c 292 Pfam PF08544 GHMP kinases C terminal 218 269 1.8E-7 T 14-10-2018 IPR013750 GHMP kinase, C-terminal domain Tharo_0554 8cf528a9aa2d323bcc33a027bf28917c 292 PIRSF PIRSF010376 18 292 9.5E-86 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 Tharo_0554 8cf528a9aa2d323bcc33a027bf28917c 292 SUPERFAMILY SSF55060 174 291 2.25E-36 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily Tharo_0330 2aeb87978caa8b79a35987f1edb5a80d 134 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 6 130 6.2E-36 T 14-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 Tharo_0330 2aeb87978caa8b79a35987f1edb5a80d 134 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 15 35 - T 14-10-2018 IPR019776 Flagellar basal body rod protein, conserved site Tharo_0330 2aeb87978caa8b79a35987f1edb5a80d 134 Pfam PF00460 Flagella basal body rod protein 9 39 3.5E-10 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 Tharo_0330 2aeb87978caa8b79a35987f1edb5a80d 134 PIRSF PIRSF002889 1 134 3.4E-40 T 14-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 Tharo_1256 265d4c0512137d76d72a8f9f47593f18 268 Gene3D G3DSA:1.10.12.10 211 268 4.4E-22 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal Tharo_1256 265d4c0512137d76d72a8f9f47593f18 268 TIGRFAM TIGR02280 PaaB1: phenylacetate degradation probable enoyl-CoA hydratase PaaB 8 268 5.1E-121 T 14-10-2018 IPR011968 Phenylacetate degradation probable enoyl-CoA hydratase PaaB GO:0010124 KEGG: 00360+5.3.3.18 Tharo_1256 265d4c0512137d76d72a8f9f47593f18 268 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 109 129 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 Tharo_1256 265d4c0512137d76d72a8f9f47593f18 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 267 9.5E-65 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Tharo_1256 265d4c0512137d76d72a8f9f47593f18 268 Gene3D G3DSA:3.90.226.10 1 209 7.1E-74 T 14-10-2018 Tharo_1256 265d4c0512137d76d72a8f9f47593f18 268 SUPERFAMILY SSF52096 4 268 1.35E-83 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_1979 848fd7590b023cacc283b8e3a80799d5 417 Pfam PF07690 Major Facilitator Superfamily 9 338 6.9E-17 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_1979 848fd7590b023cacc283b8e3a80799d5 417 Gene3D G3DSA:1.20.1250.20 4 398 6.8E-21 T 14-10-2018 Tharo_1979 848fd7590b023cacc283b8e3a80799d5 417 SUPERFAMILY SSF103473 5 394 8.37E-24 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_1807 e482d22046dc027277456cffaf67aad5 154 SUPERFAMILY SSF48657 25 122 9.68E-27 T 14-10-2018 IPR036442 ProQ/FinO domain superfamily Tharo_1807 e482d22046dc027277456cffaf67aad5 154 Pfam PF04352 ProQ/FINO family 34 129 6.4E-21 T 14-10-2018 IPR016103 ProQ/FinO domain Tharo_1807 e482d22046dc027277456cffaf67aad5 154 SMART SM00945 26 133 1.3E-24 T 14-10-2018 IPR016103 ProQ/FinO domain Tharo_1807 e482d22046dc027277456cffaf67aad5 154 Gene3D G3DSA:1.10.1710.10 2 121 2.8E-28 T 14-10-2018 IPR036442 ProQ/FinO domain superfamily Tharo_0487 ac38afb924d4209f3713e918260fc6ca 209 Gene3D G3DSA:3.20.20.70 2 209 1.8E-55 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_0487 ac38afb924d4209f3713e918260fc6ca 209 Pfam PF02581 Thiamine monophosphate synthase 12 192 6.8E-51 T 14-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Tharo_0487 ac38afb924d4209f3713e918260fc6ca 209 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 12 201 1.8E-49 T 14-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Tharo_0487 ac38afb924d4209f3713e918260fc6ca 209 SUPERFAMILY SSF51391 6 206 2.49E-58 T 14-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Tharo_0487 ac38afb924d4209f3713e918260fc6ca 209 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 10 208 23.599 T 14-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Tharo_1129 6356319632fe72b205c67f32b8ff83f7 182 SMART SM00347 36 136 1.7E-18 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_1129 6356319632fe72b205c67f32b8ff83f7 182 Gene3D G3DSA:1.10.10.10 13 153 2.4E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1129 6356319632fe72b205c67f32b8ff83f7 182 SUPERFAMILY SSF46785 19 150 4.29E-31 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1129 6356319632fe72b205c67f32b8ff83f7 182 Pfam PF01047 MarR family 43 101 2.9E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_2452 938f57e361de2cbaadaf5c95d0cc9d5d 442 Gene3D G3DSA:3.10.50.40 297 397 7.3E-74 T 14-10-2018 Tharo_2452 938f57e361de2cbaadaf5c95d0cc9d5d 442 SUPERFAMILY SSF109998 38 213 4.51E-43 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily Tharo_2452 938f57e361de2cbaadaf5c95d0cc9d5d 442 Pfam PF00639 PPIC-type PPIASE domain 190 283 1.2E-18 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 Tharo_2452 938f57e361de2cbaadaf5c95d0cc9d5d 442 Pfam PF13616 PPIC-type PPIASE domain 291 395 2.6E-25 T 14-10-2018 Tharo_2452 938f57e361de2cbaadaf5c95d0cc9d5d 442 Hamap MF_01183 Chaperone SurA [surA]. 12 440 34.861 T 14-10-2018 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0043165|GO:0050821|GO:0051082|GO:0060274 Tharo_2452 938f57e361de2cbaadaf5c95d0cc9d5d 442 Gene3D G3DSA:3.10.50.40 188 398 7.3E-74 T 14-10-2018 Tharo_2452 938f57e361de2cbaadaf5c95d0cc9d5d 442 SUPERFAMILY SSF54534 294 394 1.05E-30 T 14-10-2018 Tharo_2452 938f57e361de2cbaadaf5c95d0cc9d5d 442 SUPERFAMILY SSF54534 184 288 5.23E-26 T 14-10-2018 Tharo_2452 938f57e361de2cbaadaf5c95d0cc9d5d 442 Pfam PF09312 SurA N-terminal domain 38 155 1.4E-40 T 14-10-2018 IPR015391 SurA N-terminal Tharo_2452 938f57e361de2cbaadaf5c95d0cc9d5d 442 Gene3D G3DSA:1.10.4030.10 35 161 9.4E-34 T 14-10-2018 Tharo_2452 938f57e361de2cbaadaf5c95d0cc9d5d 442 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 334 354 - T 14-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 Tharo_3104 c9825033acfa2187067ed1fbde25597b 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 14-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 Tharo_3104 c9825033acfa2187067ed1fbde25597b 112 SUPERFAMILY SSF54913 1 112 3.5E-44 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta Tharo_3104 c9825033acfa2187067ed1fbde25597b 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 14-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 Tharo_3104 c9825033acfa2187067ed1fbde25597b 112 PRINTS PR00340 P-II protein signature 2 17 4.3E-42 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Tharo_3104 c9825033acfa2187067ed1fbde25597b 112 PRINTS PR00340 P-II protein signature 23 41 4.3E-42 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Tharo_3104 c9825033acfa2187067ed1fbde25597b 112 PRINTS PR00340 P-II protein signature 52 75 4.3E-42 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Tharo_3104 c9825033acfa2187067ed1fbde25597b 112 PRINTS PR00340 P-II protein signature 83 103 4.3E-42 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Tharo_3104 c9825033acfa2187067ed1fbde25597b 112 SMART SM00938 4 105 3.9E-64 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Tharo_3104 c9825033acfa2187067ed1fbde25597b 112 Gene3D G3DSA:3.30.70.120 1 112 1.4E-45 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Tharo_3104 c9825033acfa2187067ed1fbde25597b 112 PIRSF PIRSF039144 1 112 1.2E-52 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Tharo_3104 c9825033acfa2187067ed1fbde25597b 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.2E-41 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Tharo_1988 6e6ea71495a86115d180328d41b5538e 423 PRINTS PR00342 Rhesus blood group protein signature 137 152 6.1E-5 T 14-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 Tharo_1988 6e6ea71495a86115d180328d41b5538e 423 PRINTS PR00342 Rhesus blood group protein signature 80 96 6.1E-5 T 14-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 Tharo_1988 6e6ea71495a86115d180328d41b5538e 423 PRINTS PR00342 Rhesus blood group protein signature 316 341 6.1E-5 T 14-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 Tharo_1988 6e6ea71495a86115d180328d41b5538e 423 PRINTS PR00342 Rhesus blood group protein signature 171 189 6.1E-5 T 14-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 Tharo_1988 6e6ea71495a86115d180328d41b5538e 423 PRINTS PR00342 Rhesus blood group protein signature 7 24 6.1E-5 T 14-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 Tharo_1988 6e6ea71495a86115d180328d41b5538e 423 SUPERFAMILY SSF103473 14 405 2.22E-44 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_1988 6e6ea71495a86115d180328d41b5538e 423 Pfam PF07690 Major Facilitator Superfamily 17 348 5.5E-27 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_1988 6e6ea71495a86115d180328d41b5538e 423 Gene3D G3DSA:1.20.1250.20 11 407 6.7E-40 T 14-10-2018 Tharo_1892 6153fd90bcd1dda55d7631369b2e39bd 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 266 282 1.7E-38 T 14-10-2018 Tharo_1892 6153fd90bcd1dda55d7631369b2e39bd 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 308 319 1.7E-38 T 14-10-2018 Tharo_1892 6153fd90bcd1dda55d7631369b2e39bd 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 283 300 1.7E-38 T 14-10-2018 Tharo_1892 6153fd90bcd1dda55d7631369b2e39bd 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 196 210 1.7E-38 T 14-10-2018 Tharo_1892 6153fd90bcd1dda55d7631369b2e39bd 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 235 249 1.7E-38 T 14-10-2018 Tharo_1892 6153fd90bcd1dda55d7631369b2e39bd 380 PRINTS PR00096 Glutamine amidotransferase superfamily signature 266 277 1.5E-10 T 14-10-2018 Tharo_1892 6153fd90bcd1dda55d7631369b2e39bd 380 PRINTS PR00096 Glutamine amidotransferase superfamily signature 238 247 1.5E-10 T 14-10-2018 Tharo_1892 6153fd90bcd1dda55d7631369b2e39bd 380 PRINTS PR00096 Glutamine amidotransferase superfamily signature 351 364 1.5E-10 T 14-10-2018 Tharo_1892 6153fd90bcd1dda55d7631369b2e39bd 380 Gene3D G3DSA:3.50.30.20 5 156 1.7E-55 T 14-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_1892 6153fd90bcd1dda55d7631369b2e39bd 380 Gene3D G3DSA:3.40.50.880 157 378 2.0E-73 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Tharo_1892 6153fd90bcd1dda55d7631369b2e39bd 380 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 7 134 8.9E-51 T 14-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_1892 6153fd90bcd1dda55d7631369b2e39bd 380 SMART SM01097 5 135 8.0E-88 T 14-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_1892 6153fd90bcd1dda55d7631369b2e39bd 380 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 5 380 48.354 T 14-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_1892 6153fd90bcd1dda55d7631369b2e39bd 380 PRINTS PR00097 Anthranilate synthase component II signature 266 277 5.7E-5 T 14-10-2018 Tharo_1892 6153fd90bcd1dda55d7631369b2e39bd 380 PRINTS PR00097 Anthranilate synthase component II signature 238 247 5.7E-5 T 14-10-2018 Tharo_1892 6153fd90bcd1dda55d7631369b2e39bd 380 PRINTS PR00097 Anthranilate synthase component II signature 351 364 5.7E-5 T 14-10-2018 Tharo_1892 6153fd90bcd1dda55d7631369b2e39bd 380 Pfam PF00117 Glutamine amidotransferase class-I 199 373 1.4E-46 T 14-10-2018 IPR017926 Glutamine amidotransferase Tharo_1892 6153fd90bcd1dda55d7631369b2e39bd 380 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 7 377 5.6E-144 T 14-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_1892 6153fd90bcd1dda55d7631369b2e39bd 380 SUPERFAMILY SSF52317 158 377 1.99E-63 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Tharo_1892 6153fd90bcd1dda55d7631369b2e39bd 380 SUPERFAMILY SSF52021 6 142 1.83E-55 T 14-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_1969 3b95371dc74b4329ba1b548f8b69441f 260 SUPERFAMILY SSF54534 115 221 3.47E-23 T 14-10-2018 Tharo_1969 3b95371dc74b4329ba1b548f8b69441f 260 SUPERFAMILY SSF109998 25 159 1.18E-17 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily Tharo_1969 3b95371dc74b4329ba1b548f8b69441f 260 Pfam PF13616 PPIC-type PPIASE domain 142 222 2.3E-18 T 14-10-2018 Tharo_1969 3b95371dc74b4329ba1b548f8b69441f 260 Gene3D G3DSA:3.10.50.40 127 256 3.6E-26 T 14-10-2018 Tharo_1175 8b93bdec3a7d5000656a136a09127104 554 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 3 553 8.3E-204 T 14-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 Tharo_1175 8b93bdec3a7d5000656a136a09127104 554 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 382 530 2.2E-50 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Tharo_1175 8b93bdec3a7d5000656a136a09127104 554 Gene3D G3DSA:3.40.50.1220 183 361 5.5E-56 T 14-10-2018 Tharo_1175 8b93bdec3a7d5000656a136a09127104 554 Gene3D G3DSA:3.40.50.970 362 553 5.0E-66 T 14-10-2018 Tharo_1175 8b93bdec3a7d5000656a136a09127104 554 SUPERFAMILY SSF52467 186 350 4.43E-55 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Tharo_1175 8b93bdec3a7d5000656a136a09127104 554 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 419 438 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 Tharo_1175 8b93bdec3a7d5000656a136a09127104 554 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 172 3.1E-58 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Tharo_1175 8b93bdec3a7d5000656a136a09127104 554 SUPERFAMILY SSF52518 2 183 1.47E-60 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_1175 8b93bdec3a7d5000656a136a09127104 554 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 191 326 2.3E-40 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 Tharo_1175 8b93bdec3a7d5000656a136a09127104 554 Gene3D G3DSA:3.40.50.970 1 178 1.6E-67 T 14-10-2018 Tharo_1175 8b93bdec3a7d5000656a136a09127104 554 SUPERFAMILY SSF52518 361 552 5.36E-68 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_0389 796f429e52d5b89527e3b34680b6ff22 134 SUPERFAMILY SSF101116 9 126 1.7E-38 T 14-10-2018 IPR036584 Flagellar protein FliS superfamily GO:0044780 Tharo_0389 796f429e52d5b89527e3b34680b6ff22 134 Gene3D G3DSA:1.20.120.340 3 128 2.5E-40 T 14-10-2018 Tharo_0389 796f429e52d5b89527e3b34680b6ff22 134 TIGRFAM TIGR00208 fliS: flagellar protein FliS 6 124 1.4E-30 T 14-10-2018 IPR003713 Flagellar protein FliS GO:0044780 Tharo_0389 796f429e52d5b89527e3b34680b6ff22 134 PIRSF PIRSF039090 1 133 1.3E-42 T 14-10-2018 IPR003713 Flagellar protein FliS GO:0044780 Tharo_0389 796f429e52d5b89527e3b34680b6ff22 134 Pfam PF02561 Flagellar protein FliS 9 124 1.1E-37 T 14-10-2018 IPR003713 Flagellar protein FliS GO:0044780 Tharo_3223 c4494c1068d8fcac98bc325834cd9616 182 Gene3D G3DSA:3.40.50.300 4 180 3.7E-55 T 14-10-2018 Tharo_3223 c4494c1068d8fcac98bc325834cd9616 182 PIRSF PIRSF006135 2 182 2.2E-51 T 14-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 Tharo_3223 c4494c1068d8fcac98bc325834cd9616 182 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 5 178 7.6E-57 T 14-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 Tharo_3223 c4494c1068d8fcac98bc325834cd9616 182 SUPERFAMILY SSF52540 5 180 9.98E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1890 7e11d1111186109a3539beffe7305e49 268 Gene3D G3DSA:3.30.360.10 128 235 1.2E-95 T 14-10-2018 Tharo_1890 7e11d1111186109a3539beffe7305e49 268 PIRSF PIRSF000161 2 268 3.0E-80 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Tharo_1890 7e11d1111186109a3539beffe7305e49 268 SUPERFAMILY SSF51735 4 267 1.21E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1890 7e11d1111186109a3539beffe7305e49 268 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 4 266 6.2E-94 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Tharo_1890 7e11d1111186109a3539beffe7305e49 268 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 129 265 6.6E-40 T 14-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Tharo_1890 7e11d1111186109a3539beffe7305e49 268 SUPERFAMILY SSF55347 128 237 8.5E-36 T 14-10-2018 Tharo_1890 7e11d1111186109a3539beffe7305e49 268 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 4 126 9.2E-37 T 14-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Tharo_1890 7e11d1111186109a3539beffe7305e49 268 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 266 34.0 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Tharo_1890 7e11d1111186109a3539beffe7305e49 268 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 151 168 - T 14-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Tharo_1890 7e11d1111186109a3539beffe7305e49 268 Gene3D G3DSA:3.40.50.720 5 265 1.2E-95 T 14-10-2018 Tharo_0620 f6173e345cd0bdddbb352171a45059d9 327 Pfam PF00482 Type II secretion system (T2SS), protein F 63 186 2.6E-16 T 14-10-2018 IPR018076 Type II secretion system F domain Tharo_0620 f6173e345cd0bdddbb352171a45059d9 327 Gene3D G3DSA:1.20.81.30 52 162 5.2E-20 T 14-10-2018 Tharo_1452 859d465367518089deb023f4f80b6be0 418 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 3 418 2.2E-147 T 14-10-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 Tharo_1452 859d465367518089deb023f4f80b6be0 418 Pfam PF02687 FtsX-like permease family 305 411 3.1E-13 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Tharo_1452 859d465367518089deb023f4f80b6be0 418 Pfam PF12704 MacB-like periplasmic core domain 29 243 1.7E-21 T 14-10-2018 IPR025857 MacB-like periplasmic core domain Tharo_1122 af2a5441078c7a9d2617a95d9e3d6876 255 Gene3D G3DSA:3.40.50.720 1 253 1.1E-72 T 14-10-2018 Tharo_1122 af2a5441078c7a9d2617a95d9e3d6876 255 SUPERFAMILY SSF51735 3 249 1.12E-61 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1122 af2a5441078c7a9d2617a95d9e3d6876 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 8.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1122 af2a5441078c7a9d2617a95d9e3d6876 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 8.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1122 af2a5441078c7a9d2617a95d9e3d6876 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 8.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1122 af2a5441078c7a9d2617a95d9e3d6876 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 8.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1122 af2a5441078c7a9d2617a95d9e3d6876 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 8.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1122 af2a5441078c7a9d2617a95d9e3d6876 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 8.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1122 af2a5441078c7a9d2617a95d9e3d6876 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.2E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1122 af2a5441078c7a9d2617a95d9e3d6876 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.2E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1122 af2a5441078c7a9d2617a95d9e3d6876 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.2E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1122 af2a5441078c7a9d2617a95d9e3d6876 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 197 4.3E-4 T 14-10-2018 Tharo_1122 af2a5441078c7a9d2617a95d9e3d6876 255 Pfam PF00106 short chain dehydrogenase 7 203 5.6E-47 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1122 af2a5441078c7a9d2617a95d9e3d6876 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Tharo_1380 60f735a0c3b420d8d21451072021e606 201 SUPERFAMILY SSF52833 1 79 1.6E-17 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_1380 60f735a0c3b420d8d21451072021e606 201 Gene3D G3DSA:3.40.30.10 3 195 6.3E-75 T 14-10-2018 Tharo_1380 60f735a0c3b420d8d21451072021e606 201 SUPERFAMILY SSF47616 81 198 5.43E-30 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily Tharo_1380 60f735a0c3b420d8d21451072021e606 201 Pfam PF14497 Glutathione S-transferase, C-terminal domain 119 197 4.3E-9 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal Tharo_1380 60f735a0c3b420d8d21451072021e606 201 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 74 2.9E-10 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 Tharo_1380 60f735a0c3b420d8d21451072021e606 201 Gene3D G3DSA:1.20.1050.10 83 188 6.3E-75 T 14-10-2018 Tharo_2089 07db4bacb366d1311edc99c35a7ce281 160 TIGRFAM TIGR02010 IscR: iron-sulfur cluster assembly transcription factor IscR 1 133 6.6E-65 T 14-10-2018 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 Tharo_2089 07db4bacb366d1311edc99c35a7ce281 160 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 131 5.1E-45 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type Tharo_2089 07db4bacb366d1311edc99c35a7ce281 160 Gene3D G3DSA:1.10.10.10 1 139 1.1E-50 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2089 07db4bacb366d1311edc99c35a7ce281 160 Pfam PF02082 Transcriptional regulator 1 83 1.3E-27 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type Tharo_2089 07db4bacb366d1311edc99c35a7ce281 160 SUPERFAMILY SSF46785 2 132 7.78E-37 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_3350 14ee375b8f9545cc9971243c5bbcb757 492 SMART SM00388 272 337 2.2E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_3350 14ee375b8f9545cc9971243c5bbcb757 492 Pfam PF08521 Two-component sensor kinase N-terminal 18 195 9.1E-7 T 14-10-2018 IPR013727 Two-component sensor kinase, N-terminal Tharo_3350 14ee375b8f9545cc9971243c5bbcb757 492 SUPERFAMILY SSF47384 256 337 1.16E-16 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_3350 14ee375b8f9545cc9971243c5bbcb757 492 PRINTS PR00344 Bacterial sensor protein C-terminal signature 475 488 3.6E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3350 14ee375b8f9545cc9971243c5bbcb757 492 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 435 3.6E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3350 14ee375b8f9545cc9971243c5bbcb757 492 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 449 3.6E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3350 14ee375b8f9545cc9971243c5bbcb757 492 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 469 3.6E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3350 14ee375b8f9545cc9971243c5bbcb757 492 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 385 489 4.5E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_3350 14ee375b8f9545cc9971243c5bbcb757 492 Pfam PF00512 His Kinase A (phospho-acceptor) domain 274 337 2.6E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_3350 14ee375b8f9545cc9971243c5bbcb757 492 SUPERFAMILY SSF55874 327 489 1.15E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_3350 14ee375b8f9545cc9971243c5bbcb757 492 SMART SM00387 384 491 1.7E-31 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_3350 14ee375b8f9545cc9971243c5bbcb757 492 Gene3D G3DSA:3.30.565.10 343 491 7.4E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_3350 14ee375b8f9545cc9971243c5bbcb757 492 Gene3D G3DSA:1.10.287.130 223 337 1.3E-19 T 14-10-2018 Tharo_3148 af7ee2ec81074e52772ca541c81f2ee5 295 Pfam PF08239 Bacterial SH3 domain 156 204 6.2E-10 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type Tharo_3148 af7ee2ec81074e52772ca541c81f2ee5 295 Gene3D G3DSA:2.30.30.40 153 208 2.8E-7 T 14-10-2018 Tharo_3148 af7ee2ec81074e52772ca541c81f2ee5 295 Pfam PF05433 Glycine zipper 2TM domain 36 77 1.2E-8 T 14-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 Tharo_0968 1b63ce4966c26334ff9f0023a31f63a3 310 Pfam PF02355 Protein export membrane protein 110 292 3.6E-62 T 14-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial Tharo_0968 1b63ce4966c26334ff9f0023a31f63a3 310 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 120 281 7.7E-46 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Tharo_0968 1b63ce4966c26334ff9f0023a31f63a3 310 SUPERFAMILY SSF82866 73 292 9.94E-38 T 14-10-2018 Tharo_0968 1b63ce4966c26334ff9f0023a31f63a3 310 Pfam PF07549 SecD/SecF GG Motif 32 55 4.1E-7 T 14-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site Tharo_0968 1b63ce4966c26334ff9f0023a31f63a3 310 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 38 284 6.1E-72 T 14-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 Tharo_0968 1b63ce4966c26334ff9f0023a31f63a3 310 Gene3D G3DSA:1.20.1640.10 98 307 3.5E-11 T 14-10-2018 Tharo_0968 1b63ce4966c26334ff9f0023a31f63a3 310 PRINTS PR01755 Bacterial translocase SecF protein signature 152 166 7.1E-27 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Tharo_0968 1b63ce4966c26334ff9f0023a31f63a3 310 PRINTS PR01755 Bacterial translocase SecF protein signature 200 218 7.1E-27 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Tharo_0968 1b63ce4966c26334ff9f0023a31f63a3 310 PRINTS PR01755 Bacterial translocase SecF protein signature 232 247 7.1E-27 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Tharo_0968 1b63ce4966c26334ff9f0023a31f63a3 310 PRINTS PR01755 Bacterial translocase SecF protein signature 37 52 7.1E-27 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Tharo_0968 1b63ce4966c26334ff9f0023a31f63a3 310 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 10 295 29.18 T 14-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 Tharo_2447 0cec849493e90ec0255ce11da6201386 419 Pfam PF01494 FAD binding domain 11 311 1.5E-16 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 Tharo_2447 0cec849493e90ec0255ce11da6201386 419 SUPERFAMILY SSF51905 11 413 1.11E-43 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_2447 0cec849493e90ec0255ce11da6201386 419 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 11 314 3.6E-69 T 14-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 Tharo_2447 0cec849493e90ec0255ce11da6201386 419 Gene3D G3DSA:3.50.50.60 11 318 2.1E-65 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_2447 0cec849493e90ec0255ce11da6201386 419 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 307 4.4E-12 T 14-10-2018 Tharo_2447 0cec849493e90ec0255ce11da6201386 419 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 11 33 4.4E-12 T 14-10-2018 Tharo_2447 0cec849493e90ec0255ce11da6201386 419 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 276 291 4.4E-12 T 14-10-2018 Tharo_2447 0cec849493e90ec0255ce11da6201386 419 Gene3D G3DSA:3.30.9.50 79 265 2.1E-65 T 14-10-2018 Tharo_3366 efbf576560f78a7fa703b703022ff09a 288 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 277 2.7E-40 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Tharo_1140 efbf576560f78a7fa703b703022ff09a 288 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 277 2.7E-40 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Tharo_0971 1f68e19eb29bf8aa55763fb7b56fd665 378 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 3 372 8.7E-155 T 14-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Tharo_0971 1f68e19eb29bf8aa55763fb7b56fd665 378 Gene3D G3DSA:3.20.20.105 1 376 5.2E-167 T 14-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Tharo_0971 1f68e19eb29bf8aa55763fb7b56fd665 378 Pfam PF01702 Queuine tRNA-ribosyltransferase 127 369 6.1E-91 T 14-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Tharo_0971 1f68e19eb29bf8aa55763fb7b56fd665 378 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 1 372 55.838 T 14-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Tharo_0971 1f68e19eb29bf8aa55763fb7b56fd665 378 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 3 371 2.2E-163 T 14-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Tharo_0971 1f68e19eb29bf8aa55763fb7b56fd665 378 SUPERFAMILY SSF51713 1 372 5.23E-160 T 14-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Tharo_0738 7873191c12b7829372c5fa0c56ee4ced 186 Pfam PF11198 Protein of unknown function (DUF2857) 8 182 1.1E-62 T 14-10-2018 IPR021364 Protein of unknown function DUF2857 Tharo_1822 428374dd92b747d8ba405de17a23bbfb 313 SUPERFAMILY SSF52402 3 187 4.19E-53 T 14-10-2018 Tharo_1822 428374dd92b747d8ba405de17a23bbfb 313 Gene3D G3DSA:3.40.50.1220 187 313 3.1E-57 T 14-10-2018 Tharo_1822 428374dd92b747d8ba405de17a23bbfb 313 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 257 283 - T 14-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 Tharo_1822 428374dd92b747d8ba405de17a23bbfb 313 Gene3D G3DSA:3.40.50.620 2 186 3.5E-54 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_1822 428374dd92b747d8ba405de17a23bbfb 313 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 193 276 3.0E-35 T 14-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 Tharo_1822 428374dd92b747d8ba405de17a23bbfb 313 SUPERFAMILY SSF52467 192 312 2.54E-47 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Tharo_1822 428374dd92b747d8ba405de17a23bbfb 313 Pfam PF01012 Electron transfer flavoprotein domain 4 174 3.3E-38 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 Tharo_1822 428374dd92b747d8ba405de17a23bbfb 313 PIRSF PIRSF000089 1 313 1.2E-106 T 14-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 Tharo_1822 428374dd92b747d8ba405de17a23bbfb 313 SMART SM00893 3 185 5.7E-51 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 Tharo_1336 eff0c7204acdd457d05def4e945ac716 210 Pfam PF01227 GTP cyclohydrolase I 29 205 3.8E-48 T 14-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 Tharo_1336 eff0c7204acdd457d05def4e945ac716 210 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 24 206 28.654 T 14-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 Tharo_1336 eff0c7204acdd457d05def4e945ac716 210 SUPERFAMILY SSF55620 18 207 2.59E-56 T 14-10-2018 Tharo_1336 eff0c7204acdd457d05def4e945ac716 210 Gene3D G3DSA:3.30.1130.10 76 209 1.3E-36 T 14-10-2018 Tharo_1336 eff0c7204acdd457d05def4e945ac716 210 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 85 101 - T 14-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 Tharo_0939 f9492fcbb163fb73b576e4f09cac8ff2 360 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 18 352 1.7E-137 T 14-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 Tharo_0939 f9492fcbb163fb73b576e4f09cac8ff2 360 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 18 356 52.097 T 14-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 Tharo_0939 f9492fcbb163fb73b576e4f09cac8ff2 360 SUPERFAMILY SSF51735 17 351 4.44E-73 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_0939 f9492fcbb163fb73b576e4f09cac8ff2 360 Gene3D G3DSA:3.90.25.10 203 351 1.2E-144 T 14-10-2018 Tharo_0939 f9492fcbb163fb73b576e4f09cac8ff2 360 Pfam PF16363 GDP-mannose 4,6 dehydratase 21 346 9.2E-133 T 14-10-2018 IPR016040 NAD(P)-binding domain Tharo_0939 f9492fcbb163fb73b576e4f09cac8ff2 360 Gene3D G3DSA:3.40.50.720 20 337 1.2E-144 T 14-10-2018 Tharo_1626 d7d98b70340a77b72e90d4d005ab1f12 146 Pfam PF09424 Yqey-like protein 6 144 6.2E-23 T 14-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 Tharo_1626 d7d98b70340a77b72e90d4d005ab1f12 146 SUPERFAMILY SSF89095 1 144 5.75E-25 T 14-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 Tharo_1626 d7d98b70340a77b72e90d4d005ab1f12 146 Gene3D G3DSA:1.10.10.410 89 145 4.9E-11 T 14-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal Tharo_1626 d7d98b70340a77b72e90d4d005ab1f12 146 Gene3D G3DSA:1.10.1510.10 1 88 2.2E-8 T 14-10-2018 Tharo_1472 6b6fddb3fe986c40be3947bc2331a2e2 865 SUPERFAMILY SSF74778 2 160 2.35E-64 T 14-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 Tharo_1472 6b6fddb3fe986c40be3947bc2331a2e2 865 Gene3D G3DSA:3.30.499.10 688 865 1.2E-63 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 Tharo_1472 6b6fddb3fe986c40be3947bc2331a2e2 865 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 1 857 0.0 T 14-10-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 Tharo_1472 6b6fddb3fe986c40be3947bc2331a2e2 865 Gene3D G3DSA:1.25.40.310 1 161 8.1E-65 T 14-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 Tharo_1472 6b6fddb3fe986c40be3947bc2331a2e2 865 Gene3D G3DSA:3.40.1060.10 387 686 1.8E-148 T 14-10-2018 IPR015932 Aconitase, domain 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-1268020|Reactome: R-HSA-71403 Tharo_1472 6b6fddb3fe986c40be3947bc2331a2e2 865 Gene3D G3DSA:3.30.499.10 407 534 1.8E-148 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 Tharo_1472 6b6fddb3fe986c40be3947bc2331a2e2 865 Pfam PF00330 Aconitase family (aconitate hydratase) 474 822 1.6E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Tharo_1472 6b6fddb3fe986c40be3947bc2331a2e2 865 PIRSF PIRSF036687 1 863 0.0 T 14-10-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 Tharo_1472 6b6fddb3fe986c40be3947bc2331a2e2 865 Pfam PF11791 Aconitate B N-terminal domain 4 156 6.8E-62 T 14-10-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 Tharo_1472 6b6fddb3fe986c40be3947bc2331a2e2 865 Pfam PF06434 Aconitate hydratase 2 N-terminus 168 384 1.3E-92 T 14-10-2018 IPR015929 Aconitase B, swivel GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 Tharo_1472 6b6fddb3fe986c40be3947bc2331a2e2 865 ProSitePatterns PS00450 Aconitase family signature 1. 707 724 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Tharo_1472 6b6fddb3fe986c40be3947bc2331a2e2 865 SUPERFAMILY SSF53732 381 858 1.57E-146 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 Tharo_1472 6b6fddb3fe986c40be3947bc2331a2e2 865 Gene3D G3DSA:3.20.19.10 164 363 1.5E-67 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 Tharo_1472 6b6fddb3fe986c40be3947bc2331a2e2 865 SUPERFAMILY SSF52016 163 374 9.03E-65 T 14-10-2018 Tharo_1125 716acbcacb542a3f2de4248653be51be 585 Gene3D G3DSA:3.30.470.20 322 428 1.0E-12 T 14-10-2018 Tharo_1125 716acbcacb542a3f2de4248653be51be 585 SUPERFAMILY SSF55729 81 248 3.14E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Tharo_1125 716acbcacb542a3f2de4248653be51be 585 Pfam PF07478 D-ala D-ala ligase C-terminus 337 427 8.6E-5 T 14-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Tharo_1125 716acbcacb542a3f2de4248653be51be 585 Gene3D G3DSA:3.30.1490.20 345 414 1.0E-12 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Tharo_1125 716acbcacb542a3f2de4248653be51be 585 TIGRFAM TIGR03103 trio_acet_GNAT: GNAT-family acetyltransferase TIGR03103 34 583 6.5E-270 T 14-10-2018 IPR017534 GNAT-acetyltransferase Tharo_1125 716acbcacb542a3f2de4248653be51be 585 Gene3D G3DSA:3.30.470.20 486 578 3.9E-11 T 14-10-2018 Tharo_1125 716acbcacb542a3f2de4248653be51be 585 Gene3D G3DSA:3.40.630.30 118 257 2.9E-18 T 14-10-2018 Tharo_1125 716acbcacb542a3f2de4248653be51be 585 Pfam PF00583 Acetyltransferase (GNAT) family 159 244 1.6E-11 T 14-10-2018 IPR000182 GNAT domain Tharo_1125 716acbcacb542a3f2de4248653be51be 585 SUPERFAMILY SSF56059 330 575 1.67E-27 T 14-10-2018 Tharo_2602 42ab4361cbbdbf46d450d007b64d549f 414 Pfam PF13356 Arm DNA-binding domain 3 87 2.3E-19 T 14-10-2018 IPR025166 Integrase, DNA-binding domain Tharo_2602 42ab4361cbbdbf46d450d007b64d549f 414 Gene3D G3DSA:1.10.443.10 217 389 7.5E-18 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Tharo_2602 42ab4361cbbdbf46d450d007b64d549f 414 SUPERFAMILY SSF56349 99 381 7.95E-56 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Tharo_2602 42ab4361cbbdbf46d450d007b64d549f 414 Gene3D G3DSA:1.10.150.130 95 205 1.1E-28 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Tharo_2602 42ab4361cbbdbf46d450d007b64d549f 414 Pfam PF00589 Phage integrase family 226 379 2.3E-18 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Tharo_2602 42ab4361cbbdbf46d450d007b64d549f 414 Gene3D G3DSA:3.30.160.390 1 88 3.5E-34 T 14-10-2018 IPR038488 Integrase, DNA-binding domain superfamily Tharo_0690 3211c519e42d9f60e766487f91e1970f 505 Pfam PF07916 TraG-like protein, N-terminal region 10 485 2.5E-96 T 14-10-2018 IPR012931 TraG-like, N-terminal Tharo_1769 69c191c7691c38bd0245c1ef03c8c129 374 Gene3D G3DSA:2.40.50.940 224 352 7.8E-12 T 14-10-2018 Tharo_1769 69c191c7691c38bd0245c1ef03c8c129 374 SUPERFAMILY SSF50331 241 351 3.4E-12 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal Tharo_1769 69c191c7691c38bd0245c1ef03c8c129 374 SUPERFAMILY SSF52540 4 245 2.4E-81 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1769 69c191c7691c38bd0245c1ef03c8c129 374 Gene3D G3DSA:3.40.50.300 3 223 7.8E-62 T 14-10-2018 Tharo_1769 69c191c7691c38bd0245c1ef03c8c129 374 Pfam PF00005 ABC transporter 20 163 8.7E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_1769 69c191c7691c38bd0245c1ef03c8c129 374 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_1769 69c191c7691c38bd0245c1ef03c8c129 374 Gene3D G3DSA:2.40.50.140 289 343 7.8E-12 T 14-10-2018 Tharo_1769 69c191c7691c38bd0245c1ef03c8c129 374 SMART SM00382 28 213 4.2E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1769 69c191c7691c38bd0245c1ef03c8c129 374 Pfam PF08402 TOBE domain 282 351 1.0E-8 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 Tharo_3281 54f91db923ae4531751778eade944867 88 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 68 1.5E-20 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC Tharo_3281 54f91db923ae4531751778eade944867 88 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 14-10-2018 IPR019812 Hydrogenase assembly chaperone, conserved site Tharo_3281 54f91db923ae4531751778eade944867 88 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 18 34 2.5E-19 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC Tharo_3281 54f91db923ae4531751778eade944867 88 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 2.5E-19 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC Tharo_3281 54f91db923ae4531751778eade944867 88 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 39 55 2.5E-19 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC Tharo_3281 54f91db923ae4531751778eade944867 88 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 57 69 2.5E-19 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC Tharo_3281 54f91db923ae4531751778eade944867 88 Gene3D G3DSA:2.40.50.970 1 71 2.4E-26 T 14-10-2018 IPR037254 HupF/HypC superfamily Tharo_3281 54f91db923ae4531751778eade944867 88 Pfam PF01455 HupF/HypC family 1 66 1.5E-26 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC Tharo_3281 54f91db923ae4531751778eade944867 88 SUPERFAMILY SSF159127 1 68 7.72E-23 T 14-10-2018 IPR037254 HupF/HypC superfamily Tharo_1222 01a39707e5105e8a7937a7c5524cdab4 638 SUPERFAMILY SSF55681 242 525 3.83E-96 T 14-10-2018 Tharo_1222 01a39707e5105e8a7937a7c5524cdab4 638 SUPERFAMILY SSF52954 529 632 1.33E-29 T 14-10-2018 Tharo_1222 01a39707e5105e8a7937a7c5524cdab4 638 SUPERFAMILY SSF55186 65 240 1.44E-66 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 Tharo_1222 01a39707e5105e8a7937a7c5524cdab4 638 Pfam PF03129 Anticodon binding domain 540 626 4.8E-20 T 14-10-2018 IPR004154 Anticodon-binding Tharo_1222 01a39707e5105e8a7937a7c5524cdab4 638 Gene3D G3DSA:3.30.980.10 69 221 7.8E-64 T 14-10-2018 Tharo_1222 01a39707e5105e8a7937a7c5524cdab4 638 Gene3D G3DSA:3.30.930.10 222 530 3.1E-124 T 14-10-2018 Tharo_1222 01a39707e5105e8a7937a7c5524cdab4 638 SMART SM00863 169 218 3.1E-26 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Tharo_1222 01a39707e5105e8a7937a7c5524cdab4 638 Gene3D G3DSA:3.30.54.20 130 186 7.8E-64 T 14-10-2018 Tharo_1222 01a39707e5105e8a7937a7c5524cdab4 638 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 218 3.2E-16 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Tharo_1222 01a39707e5105e8a7937a7c5524cdab4 638 Gene3D G3DSA:3.10.20.30 3 63 3.6E-21 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Tharo_1222 01a39707e5105e8a7937a7c5524cdab4 638 SUPERFAMILY SSF81271 3 61 3.27E-14 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 Tharo_1222 01a39707e5105e8a7937a7c5524cdab4 638 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 633 34.005 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Tharo_1222 01a39707e5105e8a7937a7c5524cdab4 638 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 318 528 1.4E-44 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_1222 01a39707e5105e8a7937a7c5524cdab4 638 Gene3D G3DSA:3.40.50.800 531 636 3.9E-30 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily Tharo_1222 01a39707e5105e8a7937a7c5524cdab4 638 Pfam PF02824 TGS domain 4 61 1.1E-8 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 Tharo_1222 01a39707e5105e8a7937a7c5524cdab4 638 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 630 6.4E-218 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Tharo_1222 01a39707e5105e8a7937a7c5524cdab4 638 PRINTS PR01047 Threonyl-tRNA synthetase signature 361 384 1.0E-52 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Tharo_1222 01a39707e5105e8a7937a7c5524cdab4 638 PRINTS PR01047 Threonyl-tRNA synthetase signature 463 491 1.0E-52 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Tharo_1222 01a39707e5105e8a7937a7c5524cdab4 638 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 356 1.0E-52 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Tharo_1222 01a39707e5105e8a7937a7c5524cdab4 638 PRINTS PR01047 Threonyl-tRNA synthetase signature 506 519 1.0E-52 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Tharo_1222 01a39707e5105e8a7937a7c5524cdab4 638 PRINTS PR01047 Threonyl-tRNA synthetase signature 533 545 1.0E-52 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Tharo_2925 0d66be5e85f05cd8d91f2634b5987a5c 394 Gene3D G3DSA:3.40.47.10 4 394 2.6E-114 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_2925 0d66be5e85f05cd8d91f2634b5987a5c 394 SUPERFAMILY SSF53901 11 387 4.55E-43 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_2925 0d66be5e85f05cd8d91f2634b5987a5c 394 Pfam PF02803 Thiolase, C-terminal domain 270 369 5.9E-10 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 Tharo_2925 0d66be5e85f05cd8d91f2634b5987a5c 394 ProSitePatterns PS00737 Thiolases signature 2. 332 348 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 Tharo_2925 0d66be5e85f05cd8d91f2634b5987a5c 394 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 78 96 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 Tharo_2925 0d66be5e85f05cd8d91f2634b5987a5c 394 Pfam PF00108 Thiolase, N-terminal domain 21 192 1.0E-14 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 Tharo_2925 0d66be5e85f05cd8d91f2634b5987a5c 394 PIRSF PIRSF000429 1 390 2.4E-56 T 14-10-2018 IPR002155 Thiolase GO:0016747 Tharo_2007 94efe115ec6d137440b14e9fb11c7888 138 SUPERFAMILY SSF88723 1 112 7.85E-14 T 14-10-2018 IPR029060 PIN-like domain superfamily Tharo_2007 94efe115ec6d137440b14e9fb11c7888 138 SMART SM00670 1 114 4.7E-17 T 14-10-2018 IPR002716 PIN domain Tharo_2007 94efe115ec6d137440b14e9fb11c7888 138 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 2 110 8.1E-16 T 14-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component Tharo_2007 94efe115ec6d137440b14e9fb11c7888 138 Pfam PF13470 PIN domain 2 111 2.9E-16 T 14-10-2018 IPR002716 PIN domain Tharo_1539 88db0bf2201f47e3a8388f9229668f72 553 Pfam PF03050 Transposase IS66 family 190 420 1.2E-57 T 14-10-2018 IPR004291 Transposase, IS66 Tharo_1539 88db0bf2201f47e3a8388f9229668f72 553 Pfam PF13007 Transposase C of IS166 homeodomain 48 101 1.5E-8 T 14-10-2018 IPR024463 Transposase TnpC, homeodomain Tharo_0364 c9b256e2106d322e543e0e839a40b3f9 232 SUPERFAMILY SSF55874 1 124 1.57E-8 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_0364 c9b256e2106d322e543e0e839a40b3f9 232 Gene3D G3DSA:3.30.565.10 1 81 1.1E-8 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_0364 c9b256e2106d322e543e0e839a40b3f9 232 Pfam PF14213 STAS-like domain of unknown function (DUF4325) 169 210 4.0E-11 T 14-10-2018 IPR025474 Domain of unknown function DUF4325 Tharo_2520 75cff669d73c51040c7e2b969fe84807 1032 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 966 1031 4.1E-20 T 14-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 Tharo_2520 75cff669d73c51040c7e2b969fe84807 1032 SUPERFAMILY SSF52374 3 720 3.18E-134 T 14-10-2018 Tharo_2520 75cff669d73c51040c7e2b969fe84807 1032 Gene3D G3DSA:1.10.730.10 714 904 2.7E-55 T 14-10-2018 Tharo_2520 75cff669d73c51040c7e2b969fe84807 1032 Pfam PF08264 Anticodon-binding domain of tRNA 761 910 8.0E-41 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 Tharo_2520 75cff669d73c51040c7e2b969fe84807 1032 TIGRFAM TIGR00422 valS: valine--tRNA ligase 4 1013 0.0 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Tharo_2520 75cff669d73c51040c7e2b969fe84807 1032 PRINTS PR00986 Valyl-tRNA synthetase signature 38 49 4.1E-30 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Tharo_2520 75cff669d73c51040c7e2b969fe84807 1032 PRINTS PR00986 Valyl-tRNA synthetase signature 549 570 4.1E-30 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Tharo_2520 75cff669d73c51040c7e2b969fe84807 1032 PRINTS PR00986 Valyl-tRNA synthetase signature 236 253 4.1E-30 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Tharo_2520 75cff669d73c51040c7e2b969fe84807 1032 PRINTS PR00986 Valyl-tRNA synthetase signature 585 603 4.1E-30 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Tharo_2520 75cff669d73c51040c7e2b969fe84807 1032 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 45 56 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_2520 75cff669d73c51040c7e2b969fe84807 1032 SUPERFAMILY SSF50677 193 395 1.44E-55 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Tharo_2520 75cff669d73c51040c7e2b969fe84807 1032 SUPERFAMILY SSF47323 721 981 4.3E-64 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_2520 75cff669d73c51040c7e2b969fe84807 1032 Hamap MF_02004 Valine--tRNA ligase [valS]. 3 1031 15.793 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Tharo_2520 75cff669d73c51040c7e2b969fe84807 1032 Gene3D G3DSA:3.40.50.620 4 197 1.2E-62 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_2520 75cff669d73c51040c7e2b969fe84807 1032 Gene3D G3DSA:3.40.50.620 389 671 2.1E-63 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_2520 75cff669d73c51040c7e2b969fe84807 1032 Gene3D G3DSA:1.10.287.380 959 1031 9.9E-17 T 14-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 Tharo_2520 75cff669d73c51040c7e2b969fe84807 1032 SUPERFAMILY SSF46589 966 1030 1.36E-16 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 Tharo_2520 75cff669d73c51040c7e2b969fe84807 1032 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 16 710 1.6E-197 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_2243 12f159f54ca7bf6f88896115851ad8c0 143 Pfam PF08334 Type II secretion system (T2SS), protein G 35 142 2.0E-39 T 14-10-2018 IPR013545 Type II secretion system protein G Tharo_2243 12f159f54ca7bf6f88896115851ad8c0 143 Pfam PF07963 Prokaryotic N-terminal methylation motif 11 32 1.5E-6 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Tharo_2243 12f159f54ca7bf6f88896115851ad8c0 143 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 11 32 3.4E-7 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Tharo_2243 12f159f54ca7bf6f88896115851ad8c0 143 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 11 31 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Tharo_2243 12f159f54ca7bf6f88896115851ad8c0 143 PRINTS PR00813 Bacterial general secretion pathway protein G signature 12 37 3.4E-15 T 14-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 Tharo_2243 12f159f54ca7bf6f88896115851ad8c0 143 PRINTS PR00813 Bacterial general secretion pathway protein G signature 48 66 3.4E-15 T 14-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 Tharo_2243 12f159f54ca7bf6f88896115851ad8c0 143 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 12 143 2.9E-48 T 14-10-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 Tharo_2243 12f159f54ca7bf6f88896115851ad8c0 143 SUPERFAMILY SSF54523 38 143 1.67E-32 T 14-10-2018 Tharo_2243 12f159f54ca7bf6f88896115851ad8c0 143 Gene3D G3DSA:3.30.700.10 35 142 5.1E-35 T 14-10-2018 Tharo_3040 50c701145198be7486f0f2c17e7549eb 309 Pfam PF03466 LysR substrate binding domain 90 293 4.1E-48 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_3040 50c701145198be7486f0f2c17e7549eb 309 SUPERFAMILY SSF46785 4 89 2.42E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_3040 50c701145198be7486f0f2c17e7549eb 309 SUPERFAMILY SSF53850 90 296 4.42E-43 T 14-10-2018 Tharo_3040 50c701145198be7486f0f2c17e7549eb 309 Gene3D G3DSA:1.10.10.10 3 91 8.1E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_3040 50c701145198be7486f0f2c17e7549eb 309 Gene3D G3DSA:3.40.190.290 93 299 4.6E-45 T 14-10-2018 Tharo_3040 50c701145198be7486f0f2c17e7549eb 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.9E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_3040 50c701145198be7486f0f2c17e7549eb 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.9E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_3040 50c701145198be7486f0f2c17e7549eb 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.9E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_3040 50c701145198be7486f0f2c17e7549eb 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 4.8E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_3034 10dfc441d5ad3308d548bbcf53338996 243 Gene3D G3DSA:3.40.50.150 51 208 1.5E-13 T 14-10-2018 Tharo_3034 10dfc441d5ad3308d548bbcf53338996 243 SUPERFAMILY SSF53335 66 205 2.36E-20 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_3034 10dfc441d5ad3308d548bbcf53338996 243 Pfam PF13489 Methyltransferase domain 66 201 4.0E-19 T 14-10-2018 Tharo_2125 0bb81f2e1ccfaa2add4cf1dfa4eb5a25 152 Pfam PF05866 Endodeoxyribonuclease RusA 7 134 1.6E-32 T 14-10-2018 IPR008822 Holliday junction resolvase RusA-like GO:0000287|GO:0006281|GO:0006310 Tharo_2125 0bb81f2e1ccfaa2add4cf1dfa4eb5a25 152 SUPERFAMILY SSF103084 1 134 1.96E-20 T 14-10-2018 IPR036614 Holliday junction resolvase RusA-like superfamily GO:0000287|GO:0006281|GO:0006310 Tharo_2125 0bb81f2e1ccfaa2add4cf1dfa4eb5a25 152 Gene3D G3DSA:3.30.1330.70 2 139 3.3E-8 T 14-10-2018 IPR036614 Holliday junction resolvase RusA-like superfamily GO:0000287|GO:0006281|GO:0006310 Tharo_1210 734224e45a7c3876ed020289c29d76a2 650 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 14 427 2.8E-139 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 Tharo_1210 734224e45a7c3876ed020289c29d76a2 650 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 13 423 4.2E-133 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 Tharo_1210 734224e45a7c3876ed020289c29d76a2 650 TIGRFAM TIGR00017 cmk: cytidylate kinase 433 640 1.0E-63 T 14-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 Tharo_1210 734224e45a7c3876ed020289c29d76a2 650 Gene3D G3DSA:3.65.10.10 20 224 1.1E-68 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 Tharo_1210 734224e45a7c3876ed020289c29d76a2 650 SUPERFAMILY SSF55205 1 427 6.54E-130 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 Tharo_1210 734224e45a7c3876ed020289c29d76a2 650 Pfam PF02224 Cytidylate kinase 435 642 9.1E-66 T 14-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 Tharo_1210 734224e45a7c3876ed020289c29d76a2 650 Hamap MF_00238 Cytidylate kinase [cmk]. 432 646 31.657 T 14-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 Tharo_1210 734224e45a7c3876ed020289c29d76a2 650 Gene3D G3DSA:3.40.50.300 430 646 3.6E-71 T 14-10-2018 Tharo_1210 734224e45a7c3876ed020289c29d76a2 650 ProSitePatterns PS00885 EPSP synthase signature 2. 342 360 - T 14-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 Tharo_1210 734224e45a7c3876ed020289c29d76a2 650 SUPERFAMILY SSF52540 432 643 1.54E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1210 734224e45a7c3876ed020289c29d76a2 650 ProSitePatterns PS00104 EPSP synthase signature 1. 89 103 - T 14-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 Tharo_1210 734224e45a7c3876ed020289c29d76a2 650 Gene3D G3DSA:3.65.10.10 233 429 8.9E-71 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 Tharo_1210 734224e45a7c3876ed020289c29d76a2 650 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 10 430 34.449 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 Tharo_3374 9f382ecb67861c3d267a17feb712a9c9 323 Gene3D G3DSA:1.10.3680.10 47 111 1.9E-5 T 14-10-2018 IPR029024 TerB-like Tharo_3374 9f382ecb67861c3d267a17feb712a9c9 323 Gene3D G3DSA:1.10.3680.10 1 46 1.7E-5 T 14-10-2018 IPR029024 TerB-like Tharo_3374 9f382ecb67861c3d267a17feb712a9c9 323 Pfam PF05099 Tellurite resistance protein TerB 6 111 7.8E-10 T 14-10-2018 IPR007791 Co-chaperone DjlA, N-terminal Tharo_3374 9f382ecb67861c3d267a17feb712a9c9 323 SUPERFAMILY SSF158682 3 121 3.79E-17 T 14-10-2018 IPR029024 TerB-like Tharo_1307 f87be12ed03015bacc8c748455c5e083 438 Gene3D G3DSA:3.30.420.40 268 409 2.7E-38 T 14-10-2018 Tharo_1307 f87be12ed03015bacc8c748455c5e083 438 TIGRFAM TIGR02259 benz_CoA_red_A: benzoyl-CoA reductase, subunit A 1 431 3.1E-282 T 14-10-2018 IPR011954 Benzoyl-CoA reductase, subunit A KEGG: 00362+1.3.7.8 Tharo_1307 f87be12ed03015bacc8c748455c5e083 438 SUPERFAMILY SSF53067 4 433 4.0E-32 T 14-10-2018 Tharo_1307 f87be12ed03015bacc8c748455c5e083 438 Gene3D G3DSA:3.30.420.40 2 63 1.4E-7 T 14-10-2018 Tharo_1307 f87be12ed03015bacc8c748455c5e083 438 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 431 1.4E-130 T 14-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 Tharo_1307 f87be12ed03015bacc8c748455c5e083 438 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 231 427 1.2E-49 T 14-10-2018 IPR008275 CoA enzyme activase Tharo_3324 f4360a5fb69bf3411ba3f4bec470d566 393 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 138 365 3.4E-120 T 14-10-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 KEGG: 00190+2.7.4.1 Tharo_3324 f4360a5fb69bf3411ba3f4bec470d566 393 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 138 364 1.2E-107 T 14-10-2018 IPR022488 Polyphosphate kinase-2-related Tharo_3324 f4360a5fb69bf3411ba3f4bec470d566 393 SUPERFAMILY SSF52540 169 351 2.98E-31 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3324 f4360a5fb69bf3411ba3f4bec470d566 393 Gene3D G3DSA:3.40.50.300 111 384 1.7E-106 T 14-10-2018 Tharo_2877 f7efd5cd5e4ddd728ac8447832cb169d 292 Gene3D G3DSA:3.30.1150.10 165 290 6.8E-24 T 14-10-2018 Tharo_2877 f7efd5cd5e4ddd728ac8447832cb169d 292 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 230 287 7.1E-8 T 14-10-2018 IPR006260 TonB/TolA, C-terminal Tharo_2877 f7efd5cd5e4ddd728ac8447832cb169d 292 SUPERFAMILY SSF74653 200 286 1.27E-14 T 14-10-2018 Tharo_2877 f7efd5cd5e4ddd728ac8447832cb169d 292 PRINTS PR01217 Proline rich extensin signature 51 72 1.0E-10 T 14-10-2018 Tharo_2877 f7efd5cd5e4ddd728ac8447832cb169d 292 PRINTS PR01217 Proline rich extensin signature 73 89 1.0E-10 T 14-10-2018 Tharo_2877 f7efd5cd5e4ddd728ac8447832cb169d 292 PRINTS PR01217 Proline rich extensin signature 38 50 1.0E-10 T 14-10-2018 Tharo_2877 f7efd5cd5e4ddd728ac8447832cb169d 292 PRINTS PR01217 Proline rich extensin signature 91 108 1.0E-10 T 14-10-2018 Tharo_2877 f7efd5cd5e4ddd728ac8447832cb169d 292 Pfam PF13103 TonB C terminal 203 286 2.3E-17 T 14-10-2018 Tharo_1233 1bb4385fa22a42805ca1e944a8190344 279 Gene3D G3DSA:3.10.350.10 38 102 2.1E-16 T 14-10-2018 IPR036779 LysM domain superfamily Tharo_1233 1bb4385fa22a42805ca1e944a8190344 279 Pfam PF01476 LysM domain 51 93 5.8E-12 T 14-10-2018 IPR018392 LysM domain Tharo_1233 1bb4385fa22a42805ca1e944a8190344 279 SUPERFAMILY SSF54106 50 93 2.35E-11 T 14-10-2018 Tharo_1233 1bb4385fa22a42805ca1e944a8190344 279 SUPERFAMILY SSF51261 154 276 4.29E-44 T 14-10-2018 IPR011055 Duplicated hybrid motif Tharo_1233 1bb4385fa22a42805ca1e944a8190344 279 SMART SM00257 50 94 5.3E-13 T 14-10-2018 IPR018392 LysM domain Tharo_1233 1bb4385fa22a42805ca1e944a8190344 279 Gene3D G3DSA:2.70.70.10 151 277 1.0E-35 T 14-10-2018 IPR011055 Duplicated hybrid motif Tharo_1233 1bb4385fa22a42805ca1e944a8190344 279 Pfam PF01551 Peptidase family M23 178 272 3.2E-30 T 14-10-2018 IPR016047 Peptidase M23 Tharo_0087 dd28881b210ed4914ace464cf95b525e 563 Pfam PF01494 FAD binding domain 34 376 1.6E-56 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 Tharo_0087 dd28881b210ed4914ace464cf95b525e 563 Gene3D G3DSA:3.40.30.120 421 563 5.7E-12 T 14-10-2018 Tharo_0087 dd28881b210ed4914ace464cf95b525e 563 Gene3D G3DSA:3.30.70.2450 211 300 6.5E-80 T 14-10-2018 Tharo_0087 dd28881b210ed4914ace464cf95b525e 563 Gene3D G3DSA:3.50.50.60 35 374 6.5E-80 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_0087 dd28881b210ed4914ace464cf95b525e 563 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 34 56 2.8E-30 T 14-10-2018 Tharo_0087 dd28881b210ed4914ace464cf95b525e 563 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 326 2.8E-30 T 14-10-2018 Tharo_0087 dd28881b210ed4914ace464cf95b525e 563 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 362 378 2.8E-30 T 14-10-2018 Tharo_0087 dd28881b210ed4914ace464cf95b525e 563 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 344 362 2.8E-30 T 14-10-2018 Tharo_0087 dd28881b210ed4914ace464cf95b525e 563 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 342 2.8E-30 T 14-10-2018 Tharo_0087 dd28881b210ed4914ace464cf95b525e 563 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 182 197 2.8E-30 T 14-10-2018 Tharo_0087 dd28881b210ed4914ace464cf95b525e 563 SUPERFAMILY SSF51905 34 407 8.3E-54 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1344 a9a2d5795f446ec82da436b9fd41cbe1 208 Gene3D G3DSA:3.90.870.10 1 205 1.1E-55 T 14-10-2018 Tharo_1344 a9a2d5795f446ec82da436b9fd41cbe1 208 SUPERFAMILY SSF55821 1 203 3.36E-58 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily Tharo_1344 a9a2d5795f446ec82da436b9fd41cbe1 208 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 8 200 4.5E-56 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 Tharo_1344 a9a2d5795f446ec82da436b9fd41cbe1 208 Pfam PF01300 Telomere recombination 23 198 8.0E-39 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 Tharo_0982 1ef861fa726f8fa62129e27905e5ae1c 678 PRINTS PR00344 Bacterial sensor protein C-terminal signature 624 634 2.1E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_0982 1ef861fa726f8fa62129e27905e5ae1c 678 PRINTS PR00344 Bacterial sensor protein C-terminal signature 659 672 2.1E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_0982 1ef861fa726f8fa62129e27905e5ae1c 678 PRINTS PR00344 Bacterial sensor protein C-terminal signature 606 620 2.1E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_0982 1ef861fa726f8fa62129e27905e5ae1c 678 PRINTS PR00344 Bacterial sensor protein C-terminal signature 635 653 2.1E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_0982 1ef861fa726f8fa62129e27905e5ae1c 678 Gene3D G3DSA:3.30.450.20 299 458 3.9E-27 T 14-10-2018 Tharo_0982 1ef861fa726f8fa62129e27905e5ae1c 678 SUPERFAMILY SSF55874 516 673 4.06E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_0982 1ef861fa726f8fa62129e27905e5ae1c 678 Pfam PF00989 PAS fold 316 428 9.9E-17 T 14-10-2018 IPR013767 PAS fold GO:0006355 Tharo_0982 1ef861fa726f8fa62129e27905e5ae1c 678 Gene3D G3DSA:1.10.287.130 459 520 6.4E-20 T 14-10-2018 Tharo_0982 1ef861fa726f8fa62129e27905e5ae1c 678 SMART SM00387 565 675 1.0E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_0982 1ef861fa726f8fa62129e27905e5ae1c 678 SMART SM00388 453 523 1.2E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_0982 1ef861fa726f8fa62129e27905e5ae1c 678 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 313 437 5.7E-26 T 14-10-2018 IPR000014 PAS domain Tharo_0982 1ef861fa726f8fa62129e27905e5ae1c 678 Pfam PF00512 His Kinase A (phospho-acceptor) domain 454 520 1.2E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_0982 1ef861fa726f8fa62129e27905e5ae1c 678 SUPERFAMILY SSF55785 302 429 8.55E-25 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_0982 1ef861fa726f8fa62129e27905e5ae1c 678 SUPERFAMILY SSF47384 442 520 8.04E-10 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_0982 1ef861fa726f8fa62129e27905e5ae1c 678 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 568 673 6.5E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_0982 1ef861fa726f8fa62129e27905e5ae1c 678 SMART SM00091 315 382 2.2E-7 T 14-10-2018 IPR000014 PAS domain Tharo_0982 1ef861fa726f8fa62129e27905e5ae1c 678 Gene3D G3DSA:3.30.565.10 522 675 4.0E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_0982 1ef861fa726f8fa62129e27905e5ae1c 678 SMART SM00086 389 431 2.6E-5 T 14-10-2018 IPR001610 PAC motif Tharo_2395 5729ff83850ff6fbbcffb92b37994f58 156 SUPERFAMILY SSF75217 2 152 2.68E-45 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases Tharo_2395 5729ff83850ff6fbbcffb92b37994f58 156 Gene3D G3DSA:3.40.1280.10 1 155 2.7E-64 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Tharo_2395 5729ff83850ff6fbbcffb92b37994f58 156 Pfam PF00588 SpoU rRNA Methylase family 2 142 1.1E-31 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Tharo_2395 5729ff83850ff6fbbcffb92b37994f58 156 PIRSF PIRSF029256 1 154 1.2E-62 T 14-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 Tharo_2395 5729ff83850ff6fbbcffb92b37994f58 156 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 151 31.951 T 14-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 Tharo_0966 b9efd328e64542ff7ca5744e3dd40f32 458 Pfam PF00206 Lyase 17 315 5.3E-59 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal Tharo_0966 b9efd328e64542ff7ca5744e3dd40f32 458 Gene3D G3DSA:1.10.275.10 1 120 1.1E-41 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal Tharo_0966 b9efd328e64542ff7ca5744e3dd40f32 458 ProSitePatterns PS00163 Fumarate lyases signature. 297 306 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 Tharo_0966 b9efd328e64542ff7ca5744e3dd40f32 458 SUPERFAMILY SSF48557 8 450 9.9E-104 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 Tharo_0966 b9efd328e64542ff7ca5744e3dd40f32 458 PRINTS PR00149 Fumarate lyase superfamily signature 166 184 2.5E-20 T 14-10-2018 IPR000362 Fumarate lyase family Tharo_0966 b9efd328e64542ff7ca5744e3dd40f32 458 PRINTS PR00149 Fumarate lyase superfamily signature 297 313 2.5E-20 T 14-10-2018 IPR000362 Fumarate lyase family Tharo_0966 b9efd328e64542ff7ca5744e3dd40f32 458 PRINTS PR00149 Fumarate lyase superfamily signature 254 281 2.5E-20 T 14-10-2018 IPR000362 Fumarate lyase family Tharo_0966 b9efd328e64542ff7ca5744e3dd40f32 458 PRINTS PR00149 Fumarate lyase superfamily signature 120 138 2.5E-20 T 14-10-2018 IPR000362 Fumarate lyase family Tharo_0966 b9efd328e64542ff7ca5744e3dd40f32 458 Pfam PF08328 Adenylosuccinate lyase C-terminal 334 448 1.4E-48 T 14-10-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 Tharo_0966 b9efd328e64542ff7ca5744e3dd40f32 458 Gene3D G3DSA:1.20.200.10 121 449 1.6E-146 T 14-10-2018 Tharo_0966 b9efd328e64542ff7ca5744e3dd40f32 458 Gene3D G3DSA:1.10.40.30 385 448 1.6E-146 T 14-10-2018 Tharo_0966 b9efd328e64542ff7ca5744e3dd40f32 458 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 15 455 4.6E-116 T 14-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Tharo_0062 115f38a5367d9c0be17657597f186cb6 156 ProSitePatterns PS00818 Dps protein family signature 1. 37 53 - T 14-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 Tharo_0062 115f38a5367d9c0be17657597f186cb6 156 Pfam PF00210 Ferritin-like domain 18 155 3.9E-29 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 Tharo_0062 115f38a5367d9c0be17657597f186cb6 156 SUPERFAMILY SSF47240 4 155 3.9E-47 T 14-10-2018 IPR009078 Ferritin-like superfamily Tharo_0062 115f38a5367d9c0be17657597f186cb6 156 Gene3D G3DSA:1.20.1260.10 1 156 9.9E-56 T 14-10-2018 IPR012347 Ferritin-like Tharo_0062 115f38a5367d9c0be17657597f186cb6 156 PIRSF PIRSF005900 1 156 3.9E-44 T 14-10-2018 IPR002177 DNA-binding protein Dps Tharo_0062 115f38a5367d9c0be17657597f186cb6 156 ProSitePatterns PS00819 Dps protein family signature 2. 63 77 - T 14-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 Tharo_0062 115f38a5367d9c0be17657597f186cb6 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 37 53 2.1E-10 T 14-10-2018 IPR002177 DNA-binding protein Dps Tharo_0062 115f38a5367d9c0be17657597f186cb6 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 61 77 2.1E-10 T 14-10-2018 IPR002177 DNA-binding protein Dps Tharo_0062 115f38a5367d9c0be17657597f186cb6 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 132 150 2.1E-10 T 14-10-2018 IPR002177 DNA-binding protein Dps Tharo_1632 203b186dffc0358e107ef9922d899811 555 SUPERFAMILY SSF53697 4 548 3.06E-206 T 14-10-2018 Tharo_1632 203b186dffc0358e107ef9922d899811 555 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 495 512 - T 14-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1632 203b186dffc0358e107ef9922d899811 555 PRINTS PR00662 Glucose-6-phosphate isomerase signature 336 357 2.8E-55 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1632 203b186dffc0358e107ef9922d899811 555 PRINTS PR00662 Glucose-6-phosphate isomerase signature 495 508 2.8E-55 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1632 203b186dffc0358e107ef9922d899811 555 PRINTS PR00662 Glucose-6-phosphate isomerase signature 147 166 2.8E-55 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1632 203b186dffc0358e107ef9922d899811 555 PRINTS PR00662 Glucose-6-phosphate isomerase signature 481 495 2.8E-55 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1632 203b186dffc0358e107ef9922d899811 555 PRINTS PR00662 Glucose-6-phosphate isomerase signature 463 481 2.8E-55 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1632 203b186dffc0358e107ef9922d899811 555 PRINTS PR00662 Glucose-6-phosphate isomerase signature 259 277 2.8E-55 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1632 203b186dffc0358e107ef9922d899811 555 Pfam PF00342 Phosphoglucose isomerase 50 542 1.1E-208 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1632 203b186dffc0358e107ef9922d899811 555 Gene3D G3DSA:1.10.1390.10 505 550 6.2E-17 T 14-10-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1632 203b186dffc0358e107ef9922d899811 555 Gene3D G3DSA:3.40.50.10490 95 289 9.5E-221 T 14-10-2018 Tharo_1632 203b186dffc0358e107ef9922d899811 555 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 43 522 41.192 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1632 203b186dffc0358e107ef9922d899811 555 Gene3D G3DSA:3.40.50.10490 10 504 9.5E-221 T 14-10-2018 Tharo_1632 203b186dffc0358e107ef9922d899811 555 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 263 276 - T 14-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_0919 fe9482c4fa6faa11ed8a4eca4ce25a75 501 Pfam PF08245 Mur ligase middle domain 108 317 4.7E-46 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Tharo_0919 fe9482c4fa6faa11ed8a4eca4ce25a75 501 Pfam PF01225 Mur ligase family, catalytic domain 21 66 3.3E-7 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 Tharo_0919 fe9482c4fa6faa11ed8a4eca4ce25a75 501 Pfam PF02875 Mur ligase family, glutamate ligase domain 340 426 1.8E-22 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Tharo_0919 fe9482c4fa6faa11ed8a4eca4ce25a75 501 Gene3D G3DSA:3.40.1390.10 2 98 1.3E-17 T 14-10-2018 Tharo_0919 fe9482c4fa6faa11ed8a4eca4ce25a75 501 Gene3D G3DSA:3.90.190.20 341 496 2.9E-54 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Tharo_0919 fe9482c4fa6faa11ed8a4eca4ce25a75 501 SUPERFAMILY SSF53244 340 493 7.46E-46 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Tharo_0919 fe9482c4fa6faa11ed8a4eca4ce25a75 501 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 21 491 2.1E-140 T 14-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 Tharo_0919 fe9482c4fa6faa11ed8a4eca4ce25a75 501 SUPERFAMILY SSF63418 14 99 6.41E-17 T 14-10-2018 IPR035911 MurE/MurF, N-terminal Tharo_0919 fe9482c4fa6faa11ed8a4eca4ce25a75 501 Gene3D G3DSA:3.40.1190.10 99 340 3.6E-76 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Tharo_0919 fe9482c4fa6faa11ed8a4eca4ce25a75 501 SUPERFAMILY SSF53623 99 336 1.7E-71 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Tharo_0919 fe9482c4fa6faa11ed8a4eca4ce25a75 501 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 4 491 32.274 T 14-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 Tharo_1038 1ecf5be70d76c8e87acf81a7f957bbb3 448 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 5 435 7.0E-148 T 14-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 Tharo_1038 1ecf5be70d76c8e87acf81a7f957bbb3 448 SUPERFAMILY SSF54675 3 133 2.47E-47 T 14-10-2018 Tharo_1038 1ecf5be70d76c8e87acf81a7f957bbb3 448 Gene3D G3DSA:3.20.20.70 149 310 8.2E-54 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_1038 1ecf5be70d76c8e87acf81a7f957bbb3 448 PIRSF PIRSF000484 1 446 4.6E-122 T 14-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 Tharo_1038 1ecf5be70d76c8e87acf81a7f957bbb3 448 Gene3D G3DSA:3.20.140.10 1 148 7.9E-58 T 14-10-2018 Tharo_1038 1ecf5be70d76c8e87acf81a7f957bbb3 448 SUPERFAMILY SSF51690 134 442 3.24E-92 T 14-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 Tharo_1038 1ecf5be70d76c8e87acf81a7f957bbb3 448 Gene3D G3DSA:3.20.140.10 311 380 1.1E-11 T 14-10-2018 Tharo_1038 1ecf5be70d76c8e87acf81a7f957bbb3 448 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 150 330 1.8E-10 T 14-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 Tharo_3011 8db5be3cb236f95d876822d5bb0dc66b 291 Pfam PF09339 IclR helix-turn-helix domain 35 85 4.1E-11 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Tharo_3011 8db5be3cb236f95d876822d5bb0dc66b 291 Pfam PF01614 Bacterial transcriptional regulator 161 278 8.5E-8 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal Tharo_3011 8db5be3cb236f95d876822d5bb0dc66b 291 Gene3D G3DSA:3.30.450.40 111 278 2.1E-27 T 14-10-2018 IPR029016 GAF-like domain superfamily Tharo_3011 8db5be3cb236f95d876822d5bb0dc66b 291 SMART SM00346 33 123 1.1E-18 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Tharo_3011 8db5be3cb236f95d876822d5bb0dc66b 291 SUPERFAMILY SSF46785 33 105 9.25E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_3011 8db5be3cb236f95d876822d5bb0dc66b 291 SUPERFAMILY SSF55781 99 282 1.57E-31 T 14-10-2018 Tharo_3011 8db5be3cb236f95d876822d5bb0dc66b 291 Gene3D G3DSA:1.10.10.10 27 101 2.6E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1531 268f0875a07be5e87987847ca3cc3ec9 98 Pfam PF13470 PIN domain 1 75 1.6E-7 T 14-10-2018 IPR002716 PIN domain Tharo_1531 268f0875a07be5e87987847ca3cc3ec9 98 SUPERFAMILY SSF88723 2 80 1.31E-5 T 14-10-2018 IPR029060 PIN-like domain superfamily Tharo_1531 268f0875a07be5e87987847ca3cc3ec9 98 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 1 81 4.1E-12 T 14-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component Tharo_3083 94181ecb8c373391cc7907a3c4ebe9dd 256 Gene3D G3DSA:1.10.12.10 199 255 1.4E-15 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal Tharo_3083 94181ecb8c373391cc7907a3c4ebe9dd 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 255 1.6E-60 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Tharo_3083 94181ecb8c373391cc7907a3c4ebe9dd 256 SUPERFAMILY SSF52096 3 255 9.08E-81 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_3083 94181ecb8c373391cc7907a3c4ebe9dd 256 Gene3D G3DSA:3.90.226.10 1 198 2.0E-66 T 14-10-2018 Tharo_3083 94181ecb8c373391cc7907a3c4ebe9dd 256 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 97 117 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 Tharo_1806 ba6d4e15313f4453e02851d3c63ab1d1 214 SUPERFAMILY SSF81342 4 196 3.37E-30 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 Tharo_1806 ba6d4e15313f4453e02851d3c63ab1d1 214 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 10 33 7.0E-8 T 14-10-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0009055|GO:0016021 Tharo_1806 ba6d4e15313f4453e02851d3c63ab1d1 214 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 156 178 7.0E-8 T 14-10-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0009055|GO:0016021 Tharo_1806 ba6d4e15313f4453e02851d3c63ab1d1 214 Gene3D G3DSA:1.20.950.20 1 181 2.5E-20 T 14-10-2018 Tharo_1806 ba6d4e15313f4453e02851d3c63ab1d1 214 Pfam PF01292 Prokaryotic cytochrome b561 8 193 5.4E-25 T 14-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 Tharo_1990 822d37a3ed1dfd6592d30ffd10eacb50 351 Pfam PF01594 AI-2E family transporter 17 345 1.8E-41 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like Tharo_3139 1c50fc36ffeb1ebccb1e3586a1e8ea8d 938 SUPERFAMILY SSF56801 109 668 8.11E-118 T 14-10-2018 Tharo_3139 1c50fc36ffeb1ebccb1e3586a1e8ea8d 938 SUPERFAMILY SSF69593 711 908 5.23E-25 T 14-10-2018 Tharo_3139 1c50fc36ffeb1ebccb1e3586a1e8ea8d 938 Pfam PF01553 Acyltransferase 753 877 8.0E-20 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Tharo_3139 1c50fc36ffeb1ebccb1e3586a1e8ea8d 938 Pfam PF00501 AMP-binding enzyme 130 566 2.1E-84 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Tharo_3139 1c50fc36ffeb1ebccb1e3586a1e8ea8d 938 Gene3D G3DSA:1.10.1200.10 15 102 1.0E-11 T 14-10-2018 IPR036736 ACP-like superfamily Tharo_3139 1c50fc36ffeb1ebccb1e3586a1e8ea8d 938 Gene3D G3DSA:3.30.300.30 561 676 2.2E-26 T 14-10-2018 Tharo_3139 1c50fc36ffeb1ebccb1e3586a1e8ea8d 938 ProSitePatterns PS00455 Putative AMP-binding domain signature. 283 294 - T 14-10-2018 IPR020845 AMP-binding, conserved site Tharo_3139 1c50fc36ffeb1ebccb1e3586a1e8ea8d 938 Gene3D G3DSA:3.40.50.12780 115 560 7.9E-147 T 14-10-2018 Tharo_3139 1c50fc36ffeb1ebccb1e3586a1e8ea8d 938 SUPERFAMILY SSF47336 17 112 6.67E-13 T 14-10-2018 IPR036736 ACP-like superfamily Tharo_3139 1c50fc36ffeb1ebccb1e3586a1e8ea8d 938 Pfam PF00550 Phosphopantetheine attachment site 35 89 9.3E-9 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain Tharo_3139 1c50fc36ffeb1ebccb1e3586a1e8ea8d 938 SMART SM00563 766 880 1.7E-26 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Tharo_0680 9369b9d7e4b2ff2ae7f21772a63a3cdc 170 Pfam PF16859 Bacterial transcriptional repressor C-terminal 58 138 1.0E-9 T 14-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Tharo_0680 9369b9d7e4b2ff2ae7f21772a63a3cdc 170 SUPERFAMILY SSF46689 1 50 7.18E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_0680 9369b9d7e4b2ff2ae7f21772a63a3cdc 170 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 29 3.6E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_0680 9369b9d7e4b2ff2ae7f21772a63a3cdc 170 SUPERFAMILY SSF48498 55 137 1.42E-9 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Tharo_0680 9369b9d7e4b2ff2ae7f21772a63a3cdc 170 Gene3D G3DSA:1.10.357.10 1 161 2.1E-23 T 14-10-2018 Tharo_1144 b2b0906ca76ef52359637d63ba85ed6d 257 SUPERFAMILY SSF53474 2 253 4.4E-42 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_1144 b2b0906ca76ef52359637d63ba85ed6d 257 Pfam PF12697 Alpha/beta hydrolase family 28 244 2.8E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_1144 b2b0906ca76ef52359637d63ba85ed6d 257 Gene3D G3DSA:3.40.50.1820 1 254 2.4E-39 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_2541 027e81f64e3c937b174a95e75a0d717f 403 Pfam PF02803 Thiolase, C-terminal domain 281 397 6.0E-16 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 Tharo_2541 027e81f64e3c937b174a95e75a0d717f 403 SUPERFAMILY SSF53901 279 398 3.84E-24 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_2541 027e81f64e3c937b174a95e75a0d717f 403 SUPERFAMILY SSF53901 11 272 1.58E-37 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_2541 027e81f64e3c937b174a95e75a0d717f 403 Pfam PF00108 Thiolase, N-terminal domain 15 265 7.9E-19 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 Tharo_2541 027e81f64e3c937b174a95e75a0d717f 403 Gene3D G3DSA:3.40.47.10 132 395 1.7E-65 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_2541 027e81f64e3c937b174a95e75a0d717f 403 Gene3D G3DSA:3.40.47.10 14 282 1.7E-65 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_2541 027e81f64e3c937b174a95e75a0d717f 403 PIRSF PIRSF000429 2 400 1.2E-56 T 14-10-2018 IPR002155 Thiolase GO:0016747 Tharo_1888 8852c1ce20bbfd66ee2217078405bb88 152 Gene3D G3DSA:3.30.1490.190 86 142 2.8E-20 T 14-10-2018 Tharo_1888 8852c1ce20bbfd66ee2217078405bb88 152 Gene3D G3DSA:1.10.10.10 1 84 3.1E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1888 8852c1ce20bbfd66ee2217078405bb88 152 Pfam PF01475 Ferric uptake regulator family 11 130 5.1E-46 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 Tharo_1888 8852c1ce20bbfd66ee2217078405bb88 152 SUPERFAMILY SSF46785 6 134 3.73E-42 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1709 86fec0add125f871cba133a05eedc6a2 510 SUPERFAMILY SSF117457 321 491 1.44E-62 T 14-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 Tharo_1709 86fec0add125f871cba133a05eedc6a2 510 Pfam PF05683 Fumarase C-terminus 292 493 3.2E-81 T 14-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 Tharo_1709 86fec0add125f871cba133a05eedc6a2 510 PIRSF PIRSF001394 1 510 3.1E-216 T 14-10-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 Tharo_1709 86fec0add125f871cba133a05eedc6a2 510 Pfam PF05681 Fumarate hydratase (Fumerase) 11 288 9.2E-101 T 14-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 Tharo_1709 86fec0add125f871cba133a05eedc6a2 510 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 12 287 1.7E-62 T 14-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 Tharo_1709 86fec0add125f871cba133a05eedc6a2 510 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 330 491 1.5E-47 T 14-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 Tharo_1709 86fec0add125f871cba133a05eedc6a2 510 Gene3D G3DSA:3.20.130.10 308 493 6.5E-60 T 14-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 Tharo_2140 62e033bae4a2602e43ab71a57616ca8d 272 Pfam PF12705 PD-(D/E)XK nuclease superfamily 14 269 8.9E-17 T 14-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type Tharo_2032 23433e0586efcbf574c68b19265fcff9 442 PRINTS PR00419 Adrenodoxin reductase family signature 5 27 1.3E-7 T 14-10-2018 Tharo_2032 23433e0586efcbf574c68b19265fcff9 442 PRINTS PR00419 Adrenodoxin reductase family signature 28 41 1.3E-7 T 14-10-2018 Tharo_2032 23433e0586efcbf574c68b19265fcff9 442 SUPERFAMILY SSF51905 1 436 1.0E-50 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_2032 23433e0586efcbf574c68b19265fcff9 442 Pfam PF01593 Flavin containing amine oxidoreductase 14 433 1.1E-26 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 Tharo_2032 23433e0586efcbf574c68b19265fcff9 442 TIGRFAM TIGR03467 HpnE: squalene-associated FAD-dependent desaturase 6 433 7.6E-143 T 14-10-2018 IPR017830 Hydroxysqualene dehydroxylase HpnE MetaCyc: PWY-7072 Tharo_2032 23433e0586efcbf574c68b19265fcff9 442 Gene3D G3DSA:3.50.50.60 4 440 9.2E-26 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1846 d8abbb4f9d778ecb25704f58dcecfd7c 257 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 8.1E-24 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_1846 d8abbb4f9d778ecb25704f58dcecfd7c 257 SUPERFAMILY SSF48008 97 239 9.42E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Tharo_1846 d8abbb4f9d778ecb25704f58dcecfd7c 257 SMART SM00895 100 232 1.2E-17 T 14-10-2018 IPR011711 GntR, C-terminal Tharo_1846 d8abbb4f9d778ecb25704f58dcecfd7c 257 Gene3D G3DSA:1.10.10.10 2 75 3.2E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1846 d8abbb4f9d778ecb25704f58dcecfd7c 257 SMART SM00345 16 75 1.3E-26 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_1846 d8abbb4f9d778ecb25704f58dcecfd7c 257 SUPERFAMILY SSF46785 7 78 1.57E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1846 d8abbb4f9d778ecb25704f58dcecfd7c 257 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 1.2E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_1846 d8abbb4f9d778ecb25704f58dcecfd7c 257 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 1.2E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_1846 d8abbb4f9d778ecb25704f58dcecfd7c 257 Pfam PF07729 FCD domain 100 231 2.6E-22 T 14-10-2018 IPR011711 GntR, C-terminal Tharo_1846 d8abbb4f9d778ecb25704f58dcecfd7c 257 Gene3D G3DSA:1.20.120.530 97 254 8.7E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Tharo_0256 c0c3c4572b20f7a0eee7fa51564bb997 473 Gene3D G3DSA:3.40.1440.10 193 291 2.1E-15 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 Tharo_0256 c0c3c4572b20f7a0eee7fa51564bb997 473 Pfam PF00929 Exonuclease 9 157 1.1E-29 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Tharo_0256 c0c3c4572b20f7a0eee7fa51564bb997 473 SUPERFAMILY SSF53098 3 176 4.61E-52 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_0256 c0c3c4572b20f7a0eee7fa51564bb997 473 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 10 168 3.2E-26 T 14-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_0256 c0c3c4572b20f7a0eee7fa51564bb997 473 SMART SM00479 6 171 1.7E-41 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Tharo_0256 c0c3c4572b20f7a0eee7fa51564bb997 473 SUPERFAMILY SSF82771 220 287 3.27E-6 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 Tharo_0256 c0c3c4572b20f7a0eee7fa51564bb997 473 Gene3D G3DSA:3.30.420.10 3 168 1.5E-43 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_1706 c83e73acd34ea2baa7775ff1732127dd 277 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 6 276 75.007 T 14-10-2018 IPR026530 Phosphoenolpyruvate synthase regulatory protein Tharo_1706 c83e73acd34ea2baa7775ff1732127dd 277 Pfam PF03618 Kinase/pyrophosphorylase 9 267 5.4E-77 T 14-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 Tharo_0666 69b36ea7cfd928388179deabc62a8196 338 Gene3D G3DSA:2.40.128.140 23 334 6.8E-75 T 14-10-2018 IPR037107 Putative outer membrane protein superfamily Tharo_0666 69b36ea7cfd928388179deabc62a8196 338 Pfam PF09982 Uncharacterized protein conserved in bacteria (DUF2219) 31 335 4.6E-92 T 14-10-2018 IPR018707 Protein of unknown function DUF2219 Tharo_2703 08a907c10172072d76b9c38ddeeed814 72 SMART SM00316 4 72 1.7E-6 T 14-10-2018 IPR022967 RNA-binding domain, S1 Tharo_2703 08a907c10172072d76b9c38ddeeed814 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.491 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 Tharo_2703 08a907c10172072d76b9c38ddeeed814 72 Gene3D G3DSA:2.40.50.140 1 72 5.5E-37 T 14-10-2018 Tharo_2703 08a907c10172072d76b9c38ddeeed814 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 1.6E-26 T 14-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 Tharo_2703 08a907c10172072d76b9c38ddeeed814 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 1.4E-37 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 Tharo_2703 08a907c10172072d76b9c38ddeeed814 72 SUPERFAMILY SSF50249 1 70 7.5E-28 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_2853 d4a35c873ac111de940926f75ce83e99 747 Gene3D G3DSA:2.170.130.10 100 221 1.3E-23 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Tharo_2853 d4a35c873ac111de940926f75ce83e99 747 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 117 747 2.4E-78 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 Tharo_2853 d4a35c873ac111de940926f75ce83e99 747 SUPERFAMILY SSF56935 75 747 2.06E-96 T 14-10-2018 Tharo_2853 d4a35c873ac111de940926f75ce83e99 747 Gene3D G3DSA:2.40.170.20 222 747 1.4E-82 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Tharo_2853 d4a35c873ac111de940926f75ce83e99 747 Pfam PF00593 TonB dependent receptor 327 745 7.3E-34 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Tharo_2853 d4a35c873ac111de940926f75ce83e99 747 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 730 747 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site Tharo_2853 d4a35c873ac111de940926f75ce83e99 747 Pfam PF07715 TonB-dependent Receptor Plug Domain 114 206 3.9E-11 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain Tharo_1620 221cc267e869fc2e63b8e2b8bdf1af7d 251 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 4 244 3.1E-87 T 14-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 Tharo_1620 221cc267e869fc2e63b8e2b8bdf1af7d 251 SUPERFAMILY SSF63892 1 245 3.53E-88 T 14-10-2018 IPR036130 Pyridoxine 5'-phosphate synthase GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 Tharo_1620 221cc267e869fc2e63b8e2b8bdf1af7d 251 Gene3D G3DSA:3.20.20.70 1 250 5.9E-97 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_1620 221cc267e869fc2e63b8e2b8bdf1af7d 251 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 248 117.106 T 14-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 Tharo_1620 221cc267e869fc2e63b8e2b8bdf1af7d 251 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 3 243 3.7E-94 T 14-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 Tharo_0943 d7952275d2ccb9451eb9b92ca205b253 375 SUPERFAMILY SSF53756 13 354 3.59E-47 T 14-10-2018 Tharo_0943 d7952275d2ccb9451eb9b92ca205b253 375 Gene3D G3DSA:3.40.50.2000 158 338 6.7E-39 T 14-10-2018 Tharo_0943 d7952275d2ccb9451eb9b92ca205b253 375 Pfam PF00534 Glycosyl transferases group 1 178 334 5.8E-26 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 Tharo_0943 d7952275d2ccb9451eb9b92ca205b253 375 Gene3D G3DSA:3.40.50.2000 72 350 6.7E-39 T 14-10-2018 Tharo_2772 93e3805ded056d80233f74c761afc7c7 156 Gene3D G3DSA:2.30.110.10 2 152 1.4E-25 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 Tharo_2772 93e3805ded056d80233f74c761afc7c7 156 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 90 6.0E-9 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 Tharo_2772 93e3805ded056d80233f74c761afc7c7 156 PIRSF PIRSF009554 1 156 1.0E-52 T 14-10-2018 IPR011194 Uncharacterised protein family UPF0306 Tharo_2772 93e3805ded056d80233f74c761afc7c7 156 SUPERFAMILY SSF50475 4 149 2.81E-25 T 14-10-2018 Tharo_0749 beda379bc73aeaf70246a3256eb1c282 115 SUPERFAMILY SSF54534 4 114 1.96E-45 T 14-10-2018 Tharo_0749 beda379bc73aeaf70246a3256eb1c282 115 Gene3D G3DSA:3.10.50.40 1 115 2.1E-49 T 14-10-2018 Tharo_0749 beda379bc73aeaf70246a3256eb1c282 115 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 23 112 5.0E-37 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain Tharo_1776 97263fd07068fac980f0caf9574d30b2 638 Pfam PF00027 Cyclic nucleotide-binding domain 52 134 1.5E-7 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Tharo_1776 97263fd07068fac980f0caf9574d30b2 638 Pfam PF00571 CBS domain 177 227 6.6E-8 T 14-10-2018 IPR000644 CBS domain Tharo_1776 97263fd07068fac980f0caf9574d30b2 638 Pfam PF00571 CBS domain 241 293 2.5E-9 T 14-10-2018 IPR000644 CBS domain Tharo_1776 97263fd07068fac980f0caf9574d30b2 638 Gene3D G3DSA:2.60.120.10 18 166 3.7E-14 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Tharo_1776 97263fd07068fac980f0caf9574d30b2 638 SUPERFAMILY SSF51206 21 159 2.09E-16 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like Tharo_1776 97263fd07068fac980f0caf9574d30b2 638 Gene3D G3DSA:3.10.580.10 171 307 6.1E-30 T 14-10-2018 Tharo_1776 97263fd07068fac980f0caf9574d30b2 638 SMART SM00116 183 231 0.023 T 14-10-2018 IPR000644 CBS domain Tharo_1776 97263fd07068fac980f0caf9574d30b2 638 SMART SM00116 248 296 5.0E-4 T 14-10-2018 IPR000644 CBS domain Tharo_1776 97263fd07068fac980f0caf9574d30b2 638 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 497 636 5.3E-42 T 14-10-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding Tharo_1776 97263fd07068fac980f0caf9574d30b2 638 SUPERFAMILY SSF54631 177 293 1.34E-27 T 14-10-2018 Tharo_1776 97263fd07068fac980f0caf9574d30b2 638 Pfam PF03445 Putative nucleotidyltransferase DUF294 321 460 4.9E-45 T 14-10-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 Tharo_0661 5d8d5f84e5b9bd4b9553ffc53d6e15e5 296 Gene3D G3DSA:3.40.190.10 90 287 6.4E-34 T 14-10-2018 Tharo_0661 5d8d5f84e5b9bd4b9553ffc53d6e15e5 296 SUPERFAMILY SSF53850 88 293 1.33E-34 T 14-10-2018 Tharo_0661 5d8d5f84e5b9bd4b9553ffc53d6e15e5 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 5.1E-22 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0661 5d8d5f84e5b9bd4b9553ffc53d6e15e5 296 Gene3D G3DSA:3.40.190.10 162 268 6.4E-34 T 14-10-2018 Tharo_0661 5d8d5f84e5b9bd4b9553ffc53d6e15e5 296 SUPERFAMILY SSF46785 1 84 2.06E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0661 5d8d5f84e5b9bd4b9553ffc53d6e15e5 296 Pfam PF03466 LysR substrate binding domain 87 292 6.5E-34 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_0661 5d8d5f84e5b9bd4b9553ffc53d6e15e5 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.4E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0661 5d8d5f84e5b9bd4b9553ffc53d6e15e5 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.4E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0661 5d8d5f84e5b9bd4b9553ffc53d6e15e5 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.4E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0661 5d8d5f84e5b9bd4b9553ffc53d6e15e5 296 Gene3D G3DSA:1.10.10.10 1 85 3.5E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0679 55aca7c0b8a5e7547ab2f036e5c1ca86 495 Gene3D G3DSA:2.20.200.10 110 362 6.5E-143 T 14-10-2018 Tharo_0679 55aca7c0b8a5e7547ab2f036e5c1ca86 495 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 20 473 8.8E-120 T 14-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 Tharo_0679 55aca7c0b8a5e7547ab2f036e5c1ca86 495 Gene3D G3DSA:1.20.1600.10 64 473 6.5E-143 T 14-10-2018 Tharo_0679 55aca7c0b8a5e7547ab2f036e5c1ca86 495 SUPERFAMILY SSF56954 9 473 6.67E-117 T 14-10-2018 Tharo_0679 55aca7c0b8a5e7547ab2f036e5c1ca86 495 Pfam PF02321 Outer membrane efflux protein 73 263 1.2E-23 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Tharo_0679 55aca7c0b8a5e7547ab2f036e5c1ca86 495 Pfam PF02321 Outer membrane efflux protein 291 471 1.8E-33 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Tharo_2203 e60682283f1179962a2932d6bcfdec3d 575 Gene3D G3DSA:3.40.50.11540 136 252 1.4E-11 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_2203 e60682283f1179962a2932d6bcfdec3d 575 Gene3D G3DSA:1.10.1060.10 361 432 8.5E-13 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Tharo_2203 e60682283f1179962a2932d6bcfdec3d 575 SUPERFAMILY SSF142019 88 293 1.7E-56 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_2203 e60682283f1179962a2932d6bcfdec3d 575 SUPERFAMILY SSF46548 324 434 2.79E-19 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Tharo_2203 e60682283f1179962a2932d6bcfdec3d 575 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 5 435 3.6E-162 T 14-10-2018 IPR010208 Ion-translocating oxidoreductase complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 Tharo_2203 e60682283f1179962a2932d6bcfdec3d 575 Pfam PF12838 4Fe-4S dicluster domain 366 418 2.5E-6 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_2203 e60682283f1179962a2932d6bcfdec3d 575 Hamap MF_00461 Ion-translocating oxidoreductase complex subunit C [rsxC]. 1 575 174.185 T 14-10-2018 IPR010208 Ion-translocating oxidoreductase complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 Tharo_2203 e60682283f1179962a2932d6bcfdec3d 575 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 132 275 1.6E-46 T 14-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_2203 e60682283f1179962a2932d6bcfdec3d 575 Pfam PF10531 SLBB domain 287 334 3.5E-11 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_2203 e60682283f1179962a2932d6bcfdec3d 575 Pfam PF13375 RnfC Barrel sandwich hybrid domain 7 108 2.3E-29 T 14-10-2018 IPR026902 RnfC Barrel sandwich hybrid domain Tharo_2203 e60682283f1179962a2932d6bcfdec3d 575 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 405 416 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_3410 bf6c366faafc401d07d4f726abf25e8e 154 Pfam PF04956 TrbC/VIRB2 family 18 110 1.3E-18 T 14-10-2018 IPR007039 Conjugal transfer TrbC/type IV secretion VirB2 Tharo_3442 70bd332218bbc37d16cf22631937abe7 423 Pfam PF00665 Integrase core domain 47 172 3.9E-16 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Tharo_0167 2db9154e9fcb767cd4dc080849eb71ec 266 Gene3D G3DSA:3.40.50.720 5 265 1.3E-68 T 14-10-2018 Tharo_0167 2db9154e9fcb767cd4dc080849eb71ec 266 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 154 182 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Tharo_0167 2db9154e9fcb767cd4dc080849eb71ec 266 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 17 198 2.1E-5 T 14-10-2018 Tharo_0167 2db9154e9fcb767cd4dc080849eb71ec 266 SUPERFAMILY SSF51735 16 265 1.15E-66 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_0167 2db9154e9fcb767cd4dc080849eb71ec 266 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 264 2.6E-47 T 14-10-2018 Tharo_0167 2db9154e9fcb767cd4dc080849eb71ec 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 1.6E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0167 2db9154e9fcb767cd4dc080849eb71ec 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 1.6E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0167 2db9154e9fcb767cd4dc080849eb71ec 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 1.6E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0167 2db9154e9fcb767cd4dc080849eb71ec 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 5.2E-34 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0167 2db9154e9fcb767cd4dc080849eb71ec 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 5.2E-34 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0167 2db9154e9fcb767cd4dc080849eb71ec 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 227 247 5.2E-34 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0167 2db9154e9fcb767cd4dc080849eb71ec 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 5.2E-34 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0167 2db9154e9fcb767cd4dc080849eb71ec 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 5.2E-34 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0167 2db9154e9fcb767cd4dc080849eb71ec 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 5.2E-34 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2058 40fba8d948d52edce1a2d507ea1ccaf6 166 SMART SM00935 11 163 4.6E-59 T 14-10-2018 IPR005632 Chaperone protein Skp GO:0051082 Tharo_2058 40fba8d948d52edce1a2d507ea1ccaf6 166 PIRSF PIRSF002094 1 166 1.2E-51 T 14-10-2018 IPR005632 Chaperone protein Skp GO:0051082 Tharo_2058 40fba8d948d52edce1a2d507ea1ccaf6 166 Pfam PF03938 Outer membrane protein (OmpH-like) 9 162 5.2E-38 T 14-10-2018 IPR005632 Chaperone protein Skp GO:0051082 Tharo_2058 40fba8d948d52edce1a2d507ea1ccaf6 166 Gene3D G3DSA:3.30.910.20 22 162 1.6E-42 T 14-10-2018 IPR024930 Skp domain superfamily Tharo_2058 40fba8d948d52edce1a2d507ea1ccaf6 166 SUPERFAMILY SSF111384 22 162 1.01E-36 T 14-10-2018 Tharo_0181 3efda66b4882c14d2efff43da8867bfe 220 Pfam PF02607 B12 binding domain 9 76 1.4E-10 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_0181 3efda66b4882c14d2efff43da8867bfe 220 SUPERFAMILY SSF47644 7 84 3.27E-11 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_0181 3efda66b4882c14d2efff43da8867bfe 220 SUPERFAMILY SSF52242 89 217 1.44E-36 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 Tharo_0181 3efda66b4882c14d2efff43da8867bfe 220 SMART SM01018 5 88 6.8E-8 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_0181 3efda66b4882c14d2efff43da8867bfe 220 Gene3D G3DSA:3.40.50.280 88 217 5.7E-41 T 14-10-2018 Tharo_0181 3efda66b4882c14d2efff43da8867bfe 220 Gene3D G3DSA:1.10.1240.10 6 82 1.2E-18 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_0181 3efda66b4882c14d2efff43da8867bfe 220 Pfam PF02310 B12 binding domain 97 208 1.1E-21 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 Tharo_2797 f351833cd402cbac22b31f8544696ebb 437 Pfam PF01595 Domain of unknown function DUF21 7 197 2.8E-38 T 14-10-2018 IPR002550 CNNM, transmembrane domain Tharo_2797 f351833cd402cbac22b31f8544696ebb 437 SUPERFAMILY SSF54631 201 336 1.3E-21 T 14-10-2018 Tharo_2797 f351833cd402cbac22b31f8544696ebb 437 SMART SM01091 347 427 7.9E-30 T 14-10-2018 IPR005170 Transporter-associated domain Tharo_2797 f351833cd402cbac22b31f8544696ebb 437 Pfam PF03471 Transporter associated domain 348 426 2.7E-21 T 14-10-2018 IPR005170 Transporter-associated domain Tharo_2797 f351833cd402cbac22b31f8544696ebb 437 Gene3D G3DSA:3.30.465.10 348 427 1.4E-29 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Tharo_2797 f351833cd402cbac22b31f8544696ebb 437 Gene3D G3DSA:3.10.580.10 195 347 1.6E-32 T 14-10-2018 Tharo_2797 f351833cd402cbac22b31f8544696ebb 437 SUPERFAMILY SSF56176 345 430 1.2E-23 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Tharo_2797 f351833cd402cbac22b31f8544696ebb 437 Pfam PF00571 CBS domain 285 333 1.7E-4 T 14-10-2018 IPR000644 CBS domain Tharo_0608 74b7b1fe236f6a4b7287c4a17a28a5b2 177 SUPERFAMILY SSF56784 1 171 1.4E-44 T 14-10-2018 IPR036412 HAD-like superfamily Tharo_0608 74b7b1fe236f6a4b7287c4a17a28a5b2 177 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 3 145 2.5E-44 T 14-10-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 Tharo_0608 74b7b1fe236f6a4b7287c4a17a28a5b2 177 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 2 144 2.5E-33 T 14-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 Tharo_0608 74b7b1fe236f6a4b7287c4a17a28a5b2 177 Gene3D G3DSA:3.40.50.1000 1 177 4.7E-52 T 14-10-2018 IPR023214 HAD superfamily Tharo_0608 74b7b1fe236f6a4b7287c4a17a28a5b2 177 PIRSF PIRSF004682 1 175 2.8E-52 T 14-10-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 Tharo_0608 74b7b1fe236f6a4b7287c4a17a28a5b2 177 Pfam PF13242 HAD-hyrolase-like 99 169 4.0E-11 T 14-10-2018 Tharo_1081 5528bcfce08cc955193aa36d43686bbb 218 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 185 31.129 T 14-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 Tharo_1081 5528bcfce08cc955193aa36d43686bbb 218 Pfam PF00551 Formyl transferase 3 179 1.3E-53 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Tharo_1081 5528bcfce08cc955193aa36d43686bbb 218 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 131 154 - T 14-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Tharo_1081 5528bcfce08cc955193aa36d43686bbb 218 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 3 188 4.4E-71 T 14-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 Tharo_1081 5528bcfce08cc955193aa36d43686bbb 218 SUPERFAMILY SSF53328 4 193 1.01E-61 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Tharo_1081 5528bcfce08cc955193aa36d43686bbb 218 Gene3D G3DSA:3.40.50.170 1 201 1.2E-76 T 14-10-2018 Tharo_0795 77511e5be747b4eb233cd2817d99be20 149 Gene3D G3DSA:3.10.129.10 9 144 2.6E-38 T 14-10-2018 Tharo_0795 77511e5be747b4eb233cd2817d99be20 149 Pfam PF03061 Thioesterase superfamily 32 105 1.3E-17 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 Tharo_0795 77511e5be747b4eb233cd2817d99be20 149 SUPERFAMILY SSF54637 17 141 1.79E-35 T 14-10-2018 IPR029069 HotDog domain superfamily Tharo_0312 591e17ee5a7356e36a7c34492eb490a7 317 Pfam PF01734 Patatin-like phospholipase 19 200 1.3E-22 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 Tharo_0312 591e17ee5a7356e36a7c34492eb490a7 317 Gene3D G3DSA:3.40.1090.10 3 315 1.1E-41 T 14-10-2018 Tharo_0312 591e17ee5a7356e36a7c34492eb490a7 317 SUPERFAMILY SSF52151 17 307 6.28E-45 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase Tharo_2342 eca05f23260afca70f10260e39231b1b 228 SUPERFAMILY SSF55811 44 202 7.18E-32 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Tharo_2342 eca05f23260afca70f10260e39231b1b 228 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 42 197 37.765 T 14-10-2018 IPR022927 RNA pyrophosphohydrolase RppH Tharo_2342 eca05f23260afca70f10260e39231b1b 228 ProSitePatterns PS00893 Nudix box signature. 79 100 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Tharo_2342 eca05f23260afca70f10260e39231b1b 228 Pfam PF00293 NUDIX domain 48 177 1.0E-22 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Tharo_2342 eca05f23260afca70f10260e39231b1b 228 Gene3D G3DSA:3.90.79.10 41 199 2.4E-43 T 14-10-2018 Tharo_2342 eca05f23260afca70f10260e39231b1b 228 PRINTS PR00502 NUDIX hydrolase family signature 74 88 3.3E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Tharo_2342 eca05f23260afca70f10260e39231b1b 228 PRINTS PR00502 NUDIX hydrolase family signature 88 103 3.3E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Tharo_2879 4d2333e1ada0bc291567d458864e0ebd 170 Hamap MF_02204 Peptidoglycan-associated lipoprotein [pal]. 1 166 27.786 T 14-10-2018 IPR039001 Peptidoglycan-associated lipoprotein GO:0009279|GO:0051301 Tharo_2879 4d2333e1ada0bc291567d458864e0ebd 170 SUPERFAMILY SSF103088 55 165 2.62E-31 T 14-10-2018 IPR036737 OmpA-like domain superfamily Tharo_2879 4d2333e1ada0bc291567d458864e0ebd 170 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 64 166 3.3E-40 T 14-10-2018 IPR014169 Peptidoglycan-associated lipoprotein, C-terminal GO:0009279 Tharo_2879 4d2333e1ada0bc291567d458864e0ebd 170 Gene3D G3DSA:3.30.1330.60 49 167 1.4E-35 T 14-10-2018 IPR036737 OmpA-like domain superfamily Tharo_2879 4d2333e1ada0bc291567d458864e0ebd 170 PRINTS PR01021 OMPA domain signature 96 111 2.4E-16 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Tharo_2879 4d2333e1ada0bc291567d458864e0ebd 170 PRINTS PR01021 OMPA domain signature 66 88 2.4E-16 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Tharo_2879 4d2333e1ada0bc291567d458864e0ebd 170 PRINTS PR01021 OMPA domain signature 111 127 2.4E-16 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Tharo_2879 4d2333e1ada0bc291567d458864e0ebd 170 Pfam PF00691 OmpA family 65 160 1.0E-18 T 14-10-2018 IPR006665 OmpA-like domain Tharo_0161 3def9f631b521443db6f0ca8e5519a50 146 Pfam PF16220 Domain of unknown function (DUF4880) 3 44 3.2E-13 T 14-10-2018 IPR032623 FecR, N-terminal Tharo_1819 e4c3ffba996ad567721c44dcc345f9b9 395 Gene3D G3DSA:1.10.540.10 3 135 8.0E-44 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Tharo_1819 e4c3ffba996ad567721c44dcc345f9b9 395 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 346 365 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Tharo_1819 e4c3ffba996ad567721c44dcc345f9b9 395 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 137 228 1.9E-20 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Tharo_1819 e4c3ffba996ad567721c44dcc345f9b9 395 SUPERFAMILY SSF56645 8 239 2.36E-77 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Tharo_1819 e4c3ffba996ad567721c44dcc345f9b9 395 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 21 133 1.3E-35 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Tharo_1819 e4c3ffba996ad567721c44dcc345f9b9 395 Gene3D G3DSA:2.40.110.10 136 240 1.4E-37 T 14-10-2018 Tharo_1819 e4c3ffba996ad567721c44dcc345f9b9 395 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 241 387 1.2E-29 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Tharo_1819 e4c3ffba996ad567721c44dcc345f9b9 395 Gene3D G3DSA:1.20.140.10 242 395 1.3E-43 T 14-10-2018 Tharo_1819 e4c3ffba996ad567721c44dcc345f9b9 395 SUPERFAMILY SSF47203 240 389 1.61E-43 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Tharo_1433 ab114c5ec85c5f5e4aceb229c33bd6ea 1255 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 787 804 - T 14-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 Tharo_1433 ab114c5ec85c5f5e4aceb229c33bd6ea 1255 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 1136 1163 - T 14-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 Tharo_1433 ab114c5ec85c5f5e4aceb229c33bd6ea 1255 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 3 40 5.4E-18 T 14-10-2018 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 Tharo_1433 ab114c5ec85c5f5e4aceb229c33bd6ea 1255 SMART SM00926 43 105 3.1E-8 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1433 ab114c5ec85c5f5e4aceb229c33bd6ea 1255 Gene3D G3DSA:3.40.50.12440 44 1254 0.0 T 14-10-2018 Tharo_1433 ab114c5ec85c5f5e4aceb229c33bd6ea 1255 Pfam PF00384 Molybdopterin oxidoreductase 108 843 5.1E-157 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1433 ab114c5ec85c5f5e4aceb229c33bd6ea 1255 SUPERFAMILY SSF50692 1093 1246 9.49E-47 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Tharo_1433 ab114c5ec85c5f5e4aceb229c33bd6ea 1255 Pfam PF01568 Molydopterin dinucleotide binding domain 1098 1213 6.8E-23 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 Tharo_1433 ab114c5ec85c5f5e4aceb229c33bd6ea 1255 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 2 1246 0.0 T 14-10-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 Tharo_1433 ab114c5ec85c5f5e4aceb229c33bd6ea 1255 SUPERFAMILY SSF53706 3 1082 0.0 T 14-10-2018 Tharo_2351 28f8b3f446f720161b4a8c4d3c660f64 900 SUPERFAMILY SSF81301 13 266 2.78E-70 T 14-10-2018 Tharo_2351 28f8b3f446f720161b4a8c4d3c660f64 900 Gene3D G3DSA:1.20.120.1510 424 535 1.7E-19 T 14-10-2018 Tharo_2351 28f8b3f446f720161b4a8c4d3c660f64 900 SUPERFAMILY SSF81593 267 416 5.73E-44 T 14-10-2018 Tharo_2351 28f8b3f446f720161b4a8c4d3c660f64 900 Pfam PF08335 GlnD PII-uridylyltransferase 277 415 7.0E-49 T 14-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 Tharo_2351 28f8b3f446f720161b4a8c4d3c660f64 900 Pfam PF08335 GlnD PII-uridylyltransferase 783 874 2.0E-7 T 14-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 Tharo_2351 28f8b3f446f720161b4a8c4d3c660f64 900 SUPERFAMILY SSF81301 499 771 1.74E-74 T 14-10-2018 Tharo_2351 28f8b3f446f720161b4a8c4d3c660f64 900 Gene3D G3DSA:1.20.120.330 265 420 2.2E-57 T 14-10-2018 Tharo_2351 28f8b3f446f720161b4a8c4d3c660f64 900 Gene3D G3DSA:1.20.120.330 768 899 3.1E-37 T 14-10-2018 Tharo_2351 28f8b3f446f720161b4a8c4d3c660f64 900 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 527 761 1.9E-65 T 14-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 Tharo_2351 28f8b3f446f720161b4a8c4d3c660f64 900 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 20 251 5.7E-62 T 14-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 Tharo_2351 28f8b3f446f720161b4a8c4d3c660f64 900 Gene3D G3DSA:3.30.460.100 22 260 9.6E-65 T 14-10-2018 Tharo_2351 28f8b3f446f720161b4a8c4d3c660f64 900 Gene3D G3DSA:3.30.460.100 536 767 8.8E-73 T 14-10-2018 Tharo_2351 28f8b3f446f720161b4a8c4d3c660f64 900 SUPERFAMILY SSF81593 773 899 2.51E-31 T 14-10-2018 Tharo_2351 28f8b3f446f720161b4a8c4d3c660f64 900 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 10 900 18.93 T 14-10-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 Tharo_1544 c2bc3c87bfc515e540fdce459a1e9222 448 Gene3D G3DSA:3.40.50.300 140 315 1.9E-58 T 14-10-2018 Tharo_1544 c2bc3c87bfc515e540fdce459a1e9222 448 SUPERFAMILY SSF52172 13 189 6.4E-40 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1544 c2bc3c87bfc515e540fdce459a1e9222 448 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 169 182 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Tharo_1544 c2bc3c87bfc515e540fdce459a1e9222 448 Pfam PF00072 Response regulator receiver domain 15 124 2.4E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1544 c2bc3c87bfc515e540fdce459a1e9222 448 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 358 367 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Tharo_1544 c2bc3c87bfc515e540fdce459a1e9222 448 Pfam PF00158 Sigma-54 interaction domain 145 311 1.4E-64 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Tharo_1544 c2bc3c87bfc515e540fdce459a1e9222 448 SUPERFAMILY SSF52540 145 387 5.44E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1544 c2bc3c87bfc515e540fdce459a1e9222 448 SMART SM00448 13 124 3.2E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1544 c2bc3c87bfc515e540fdce459a1e9222 448 SMART SM00382 165 308 2.9E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1544 c2bc3c87bfc515e540fdce459a1e9222 448 Gene3D G3DSA:3.40.50.2300 11 139 1.5E-31 T 14-10-2018 Tharo_1544 c2bc3c87bfc515e540fdce459a1e9222 448 Gene3D G3DSA:1.10.8.60 316 393 8.0E-26 T 14-10-2018 Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 Pfam PF07517 SecA DEAD-like domain 6 403 8.8E-134 T 14-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 826 0.0 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 Gene3D G3DSA:3.90.1440.10 229 370 4.1E-178 T 14-10-2018 Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 SUPERFAMILY SSF81767 230 370 8.63E-43 T 14-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 SUPERFAMILY SSF81886 629 896 7.32E-84 T 14-10-2018 IPR036266 SecA, Wing/Scaffold superfamily Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 Pfam PF01043 SecA preprotein cross-linking domain 232 360 9.0E-37 T 14-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 PRINTS PR00906 SecA protein signature 101 115 6.9E-73 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 PRINTS PR00906 SecA protein signature 117 127 6.9E-73 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 PRINTS PR00906 SecA protein signature 170 190 6.9E-73 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 PRINTS PR00906 SecA protein signature 415 428 6.9E-73 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 PRINTS PR00906 SecA protein signature 63 87 6.9E-73 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 PRINTS PR00906 SecA protein signature 341 363 6.9E-73 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 PRINTS PR00906 SecA protein signature 378 395 6.9E-73 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 Pfam PF02810 SEC-C motif 888 906 1.8E-10 T 14-10-2018 IPR004027 SEC-C motif Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 Gene3D G3DSA:3.40.50.300 419 628 8.9E-87 T 14-10-2018 Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 Gene3D G3DSA:3.10.450.50 856 907 3.4E-9 T 14-10-2018 Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 Pfam PF07516 SecA Wing and Scaffold domain 626 839 1.4E-66 T 14-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 SMART SM00958 228 360 3.8E-76 T 14-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 ProSitePatterns PS01312 SecA family signature. 502 517 - T 14-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 841 20.001 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 SMART SM00957 6 404 0.0 T 14-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 SUPERFAMILY SSF52540 419 627 1.43E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 SUPERFAMILY SSF52540 5 417 1.43E-85 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 Gene3D G3DSA:1.10.3060.10 630 842 3.7E-74 T 14-10-2018 Tharo_0964 f2552ed98796842496ba4604cdc4fd91 908 Gene3D G3DSA:3.40.50.300 23 417 4.1E-178 T 14-10-2018 Tharo_1158 cca1851aa869d1c1007f2af32254a1f8 196 TIGRFAM TIGR01848 PHA_reg_PhaR: polyhydroxyalkanoate synthesis repressor PhaR 6 112 3.4E-44 T 14-10-2018 IPR010134 Polyhydroxyalkanoate synthesis repressor PhaR GO:0006355 Tharo_1158 cca1851aa869d1c1007f2af32254a1f8 196 Pfam PF07879 PHB/PHA accumulation regulator DNA-binding domain 7 66 4.0E-31 T 14-10-2018 IPR012909 PHA accumulation regulator DNA-binding, N-terminal Tharo_1158 cca1851aa869d1c1007f2af32254a1f8 196 Pfam PF05233 PHB accumulation regulatory domain 125 161 8.4E-14 T 14-10-2018 IPR007897 PHB accumulation regulatory Tharo_1158 cca1851aa869d1c1007f2af32254a1f8 196 Pfam PF05233 PHB accumulation regulatory domain 71 110 5.5E-18 T 14-10-2018 IPR007897 PHB accumulation regulatory Tharo_3353 727c901d9f89f9e11131283e59900d5a 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 8.9E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3353 727c901d9f89f9e11131283e59900d5a 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 8.9E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3353 727c901d9f89f9e11131283e59900d5a 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 8.9E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3353 727c901d9f89f9e11131283e59900d5a 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 8.9E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3353 727c901d9f89f9e11131283e59900d5a 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 8.9E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3353 727c901d9f89f9e11131283e59900d5a 273 Gene3D G3DSA:3.40.50.720 1 260 4.8E-59 T 14-10-2018 Tharo_3353 727c901d9f89f9e11131283e59900d5a 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 1.3E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3353 727c901d9f89f9e11131283e59900d5a 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 1.3E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3353 727c901d9f89f9e11131283e59900d5a 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.3E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3353 727c901d9f89f9e11131283e59900d5a 273 SUPERFAMILY SSF51735 1 256 1.61E-59 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_3353 727c901d9f89f9e11131283e59900d5a 273 Pfam PF00106 short chain dehydrogenase 8 189 7.3E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3353 727c901d9f89f9e11131283e59900d5a 273 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 212 4.3E-5 T 14-10-2018 Tharo_3353 727c901d9f89f9e11131283e59900d5a 273 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Tharo_0673 55def1e1a9a55ec57b21039599e595c1 809 Pfam PF11339 Protein of unknown function (DUF3141) 33 610 7.0E-289 T 14-10-2018 IPR024501 Protein of unknown function DUF3141 Tharo_0673 55def1e1a9a55ec57b21039599e595c1 809 SUPERFAMILY SSF53474 68 383 2.13E-26 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_0541 fae4b8550cb611c4eec66a3de2335b49 433 SMART SM00710 177 198 2100.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat Tharo_0541 fae4b8550cb611c4eec66a3de2335b49 433 SMART SM00710 243 265 9.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat Tharo_0541 fae4b8550cb611c4eec66a3de2335b49 433 SMART SM00710 311 348 4000.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat Tharo_0541 fae4b8550cb611c4eec66a3de2335b49 433 SMART SM00710 199 220 2000.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat Tharo_0541 fae4b8550cb611c4eec66a3de2335b49 433 SMART SM00710 147 176 39.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat Tharo_0541 fae4b8550cb611c4eec66a3de2335b49 433 SMART SM00710 95 123 24.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat Tharo_0541 fae4b8550cb611c4eec66a3de2335b49 433 SMART SM00710 288 309 12.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat Tharo_0541 fae4b8550cb611c4eec66a3de2335b49 433 SMART SM00710 266 287 27.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat Tharo_0541 fae4b8550cb611c4eec66a3de2335b49 433 SMART SM00710 125 146 1200.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat Tharo_0541 fae4b8550cb611c4eec66a3de2335b49 433 Pfam PF05048 Periplasmic copper-binding protein (NosD) 157 378 4.4E-61 T 14-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 Tharo_0541 fae4b8550cb611c4eec66a3de2335b49 433 TIGRFAM TIGR04247 NosD_copper_fam: nitrous oxide reductase family maturation protein NosD 42 414 2.6E-135 T 14-10-2018 IPR026464 Nitrous oxide reductase family maturation protein NosD Tharo_0541 fae4b8550cb611c4eec66a3de2335b49 433 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 260 302 4.9E-9 T 14-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 Tharo_0541 fae4b8550cb611c4eec66a3de2335b49 433 Gene3D G3DSA:2.160.20.10 28 351 2.4E-28 T 14-10-2018 IPR012334 Pectin lyase fold Tharo_0541 fae4b8550cb611c4eec66a3de2335b49 433 SUPERFAMILY SSF51126 36 401 1.78E-64 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor Tharo_0541 fae4b8550cb611c4eec66a3de2335b49 433 SMART SM00722 49 197 6.0E-9 T 14-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain Tharo_0541 fae4b8550cb611c4eec66a3de2335b49 433 SMART SM00722 203 362 3.0E-4 T 14-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain Tharo_2731 3216b853ca6a9dda84a60d4413d81b4c 1379 Gene3D G3DSA:2.40.50.150 858 975 4.8E-43 T 14-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2731 3216b853ca6a9dda84a60d4413d81b4c 1379 Gene3D G3DSA:2.40.270.10 1063 1277 9.4E-85 T 14-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2731 3216b853ca6a9dda84a60d4413d81b4c 1379 Pfam PF04565 RNA polymerase Rpb2, domain 3 538 605 1.1E-31 T 14-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2731 3216b853ca6a9dda84a60d4413d81b4c 1379 Pfam PF04560 RNA polymerase Rpb2, domain 7 1301 1375 5.9E-27 T 14-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2731 3216b853ca6a9dda84a60d4413d81b4c 1379 SUPERFAMILY SSF64484 12 1377 0.0 T 14-10-2018 Tharo_2731 3216b853ca6a9dda84a60d4413d81b4c 1379 Gene3D G3DSA:2.40.270.10 815 857 2.9E-6 T 14-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2731 3216b853ca6a9dda84a60d4413d81b4c 1379 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1377 12.271 T 14-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2731 3216b853ca6a9dda84a60d4413d81b4c 1379 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1373 0.0 T 14-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2731 3216b853ca6a9dda84a60d4413d81b4c 1379 Gene3D G3DSA:3.90.1100.10 18 175 2.5E-53 T 14-10-2018 Tharo_2731 3216b853ca6a9dda84a60d4413d81b4c 1379 Gene3D G3DSA:3.90.1100.10 668 738 2.0E-21 T 14-10-2018 Tharo_2731 3216b853ca6a9dda84a60d4413d81b4c 1379 Gene3D G3DSA:3.90.1110.10 323 467 1.2E-26 T 14-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2731 3216b853ca6a9dda84a60d4413d81b4c 1379 Pfam PF00562 RNA polymerase Rpb2, domain 6 743 1299 3.1E-161 T 14-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2731 3216b853ca6a9dda84a60d4413d81b4c 1379 Pfam PF10385 RNA polymerase beta subunit external 1 domain 616 681 1.2E-24 T 14-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2731 3216b853ca6a9dda84a60d4413d81b4c 1379 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1101 1113 - T 14-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2731 3216b853ca6a9dda84a60d4413d81b4c 1379 Pfam PF04563 RNA polymerase beta subunit 27 525 3.5E-39 T 14-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2731 3216b853ca6a9dda84a60d4413d81b4c 1379 Gene3D G3DSA:3.90.1100.10 468 653 1.4E-71 T 14-10-2018 Tharo_2731 3216b853ca6a9dda84a60d4413d81b4c 1379 Gene3D G3DSA:3.90.1800.10 1287 1342 6.8E-11 T 14-10-2018 Tharo_2731 3216b853ca6a9dda84a60d4413d81b4c 1379 Pfam PF04561 RNA polymerase Rpb2, domain 2 445 479 1.3E-6 T 14-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2731 3216b853ca6a9dda84a60d4413d81b4c 1379 Pfam PF04561 RNA polymerase Rpb2, domain 2 155 233 7.5E-8 T 14-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2731 3216b853ca6a9dda84a60d4413d81b4c 1379 Gene3D G3DSA:2.40.50.100 739 813 1.1E-28 T 14-10-2018 Tharo_0633 9c9e17b9bf602894af66281bd1f5c2e9 135 PIRSF PIRSF006092 24 127 3.1E-23 T 14-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 Tharo_0633 9c9e17b9bf602894af66281bd1f5c2e9 135 SUPERFAMILY SSF54534 48 125 9.55E-16 T 14-10-2018 Tharo_0633 9c9e17b9bf602894af66281bd1f5c2e9 135 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 49 124 4.8E-17 T 14-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 Tharo_0633 9c9e17b9bf602894af66281bd1f5c2e9 135 Gene3D G3DSA:3.10.50.30 44 134 1.7E-28 T 14-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 Tharo_0633 9c9e17b9bf602894af66281bd1f5c2e9 135 Gene3D G3DSA:1.10.286.20 1 43 2.4E-7 T 14-10-2018 Tharo_0633 9c9e17b9bf602894af66281bd1f5c2e9 135 Pfam PF14760 Rnk N-terminus 3 42 8.9E-11 T 14-10-2018 IPR029462 Regulator of nucleoside diphosphate kinase, N-terminal domain Tharo_1987 2930320563fadc7e27e05a6661598b37 601 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 484 495 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1987 2930320563fadc7e27e05a6661598b37 601 Gene3D G3DSA:3.40.50.11540 206 384 8.7E-75 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1987 2930320563fadc7e27e05a6661598b37 601 Gene3D G3DSA:3.10.20.600 385 466 4.7E-15 T 14-10-2018 Tharo_1987 2930320563fadc7e27e05a6661598b37 601 SUPERFAMILY SSF52833 5 168 4.36E-31 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_1987 2930320563fadc7e27e05a6661598b37 601 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 320 335 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1987 2930320563fadc7e27e05a6661598b37 601 Pfam PF10531 SLBB domain 397 430 6.8E-7 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1987 2930320563fadc7e27e05a6661598b37 601 Gene3D G3DSA:3.40.30.10 70 161 7.8E-8 T 14-10-2018 Tharo_1987 2930320563fadc7e27e05a6661598b37 601 SUPERFAMILY SSF140490 468 559 7.98E-25 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1987 2930320563fadc7e27e05a6661598b37 601 SMART SM00928 471 516 5.2E-20 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1987 2930320563fadc7e27e05a6661598b37 601 Gene3D G3DSA:1.20.1440.230 469 563 3.1E-23 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1987 2930320563fadc7e27e05a6661598b37 601 Gene3D G3DSA:1.10.10.1590 3 67 3.4E-8 T 14-10-2018 Tharo_1987 2930320563fadc7e27e05a6661598b37 601 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 472 554 2.6E-20 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1987 2930320563fadc7e27e05a6661598b37 601 SUPERFAMILY SSF142984 394 463 1.7E-12 T 14-10-2018 Tharo_1987 2930320563fadc7e27e05a6661598b37 601 SUPERFAMILY SSF142019 188 393 3.66E-74 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1987 2930320563fadc7e27e05a6661598b37 601 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 201 369 9.1E-45 T 14-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1987 2930320563fadc7e27e05a6661598b37 601 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 9 143 8.5E-24 T 14-10-2018 Tharo_1933 4babd86392103414d843fbab5e5272e6 223 Pfam PF00027 Cyclic nucleotide-binding domain 36 121 2.8E-24 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Tharo_1933 4babd86392103414d843fbab5e5272e6 223 Gene3D G3DSA:1.10.10.10 151 217 4.4E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1933 4babd86392103414d843fbab5e5272e6 223 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 176 192 8.4E-6 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Tharo_1933 4babd86392103414d843fbab5e5272e6 223 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 192 207 8.4E-6 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Tharo_1933 4babd86392103414d843fbab5e5272e6 223 SMART SM00419 169 218 3.9E-10 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Tharo_1933 4babd86392103414d843fbab5e5272e6 223 SMART SM00100 17 135 8.9E-24 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Tharo_1933 4babd86392103414d843fbab5e5272e6 223 SUPERFAMILY SSF46785 152 217 1.46E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1933 4babd86392103414d843fbab5e5272e6 223 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 85 102 - T 14-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site Tharo_1933 4babd86392103414d843fbab5e5272e6 223 Gene3D G3DSA:2.60.120.10 10 150 1.1E-38 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Tharo_1933 4babd86392103414d843fbab5e5272e6 223 SUPERFAMILY SSF51206 12 150 1.44E-36 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like Tharo_1933 4babd86392103414d843fbab5e5272e6 223 PRINTS PR00103 cAMP-dependent protein kinase signature 83 92 3.7E-5 T 14-10-2018 Tharo_1933 4babd86392103414d843fbab5e5272e6 223 PRINTS PR00103 cAMP-dependent protein kinase signature 53 67 3.7E-5 T 14-10-2018 Tharo_1933 4babd86392103414d843fbab5e5272e6 223 PRINTS PR00103 cAMP-dependent protein kinase signature 95 106 3.7E-5 T 14-10-2018 Tharo_1933 4babd86392103414d843fbab5e5272e6 223 PRINTS PR00103 cAMP-dependent protein kinase signature 38 52 3.7E-5 T 14-10-2018 Tharo_1933 4babd86392103414d843fbab5e5272e6 223 Pfam PF13545 Crp-like helix-turn-helix domain 155 218 2.0E-15 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Tharo_0125 d9177ab9a0e8331cc591ae776948c013 142 Gene3D G3DSA:3.30.428.10 15 142 9.3E-38 T 14-10-2018 IPR036265 HIT-like superfamily Tharo_0125 d9177ab9a0e8331cc591ae776948c013 142 Pfam PF01230 HIT domain 15 103 3.5E-16 T 14-10-2018 IPR001310 Histidine triad (HIT) protein Tharo_0125 d9177ab9a0e8331cc591ae776948c013 142 SUPERFAMILY SSF54197 6 139 7.58E-37 T 14-10-2018 IPR036265 HIT-like superfamily Tharo_0125 d9177ab9a0e8331cc591ae776948c013 142 PIRSF PIRSF000714 7 141 1.2E-39 T 14-10-2018 IPR026026 Histidine triad hydrolase, Hint-type Tharo_2428 502d098be1853aaa474e3af6e80ba168 675 SUPERFAMILY SSF52518 338 533 4.82E-68 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_2428 502d098be1853aaa474e3af6e80ba168 675 Gene3D G3DSA:3.40.50.920 547 675 1.5E-44 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Tharo_2428 502d098be1853aaa474e3af6e80ba168 675 Pfam PF02780 Transketolase, C-terminal domain 559 667 2.8E-14 T 14-10-2018 IPR033248 Transketolase, C-terminal domain Tharo_2428 502d098be1853aaa474e3af6e80ba168 675 ProSitePatterns PS00801 Transketolase signature 1. 20 40 - T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Tharo_2428 502d098be1853aaa474e3af6e80ba168 675 SUPERFAMILY SSF52922 543 675 3.93E-43 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Tharo_2428 502d098be1853aaa474e3af6e80ba168 675 TIGRFAM TIGR00232 tktlase_bact: transketolase 18 674 4.2E-298 T 14-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 Tharo_2428 502d098be1853aaa474e3af6e80ba168 675 SUPERFAMILY SSF52518 15 329 1.37E-121 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_2428 502d098be1853aaa474e3af6e80ba168 675 Gene3D G3DSA:3.40.50.970 335 545 1.4E-84 T 14-10-2018 Tharo_2428 502d098be1853aaa474e3af6e80ba168 675 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 17 342 5.7E-166 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Tharo_2428 502d098be1853aaa474e3af6e80ba168 675 SMART SM00861 363 533 2.5E-67 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Tharo_2428 502d098be1853aaa474e3af6e80ba168 675 Gene3D G3DSA:3.40.50.970 14 334 6.3E-133 T 14-10-2018 Tharo_2428 502d098be1853aaa474e3af6e80ba168 675 ProSitePatterns PS00802 Transketolase signature 2. 475 491 - T 14-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Tharo_2428 502d098be1853aaa474e3af6e80ba168 675 Pfam PF02779 Transketolase, pyrimidine binding domain 362 532 9.6E-47 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Tharo_0895 89f49556e67088688e047a1bced2eb33 441 Pfam PF02321 Outer membrane efflux protein 30 218 1.5E-25 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Tharo_0895 89f49556e67088688e047a1bced2eb33 441 Pfam PF02321 Outer membrane efflux protein 243 425 6.1E-23 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Tharo_0895 89f49556e67088688e047a1bced2eb33 441 Gene3D G3DSA:1.20.1600.10 26 441 3.9E-107 T 14-10-2018 Tharo_0895 89f49556e67088688e047a1bced2eb33 441 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 25 439 2.0E-97 T 14-10-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0015562|GO:0019867|GO:0055085 Tharo_0895 89f49556e67088688e047a1bced2eb33 441 SUPERFAMILY SSF56954 8 430 7.06E-81 T 14-10-2018 Tharo_0889 b90feda42f193e2d4575bb7529a8cb02 134 SUPERFAMILY SSF81593 1 126 2.43E-26 T 14-10-2018 Tharo_0889 b90feda42f193e2d4575bb7529a8cb02 134 TIGRFAM TIGR01987 HI0074: nucleotidyltransferase substrate binding protein, HI0074 family 12 114 7.3E-16 T 14-10-2018 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 Tharo_0889 b90feda42f193e2d4575bb7529a8cb02 134 Pfam PF08780 Nucleotidyltransferase substrate binding protein like 7 127 8.6E-26 T 14-10-2018 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 Tharo_0889 b90feda42f193e2d4575bb7529a8cb02 134 Gene3D G3DSA:1.20.120.330 10 128 1.7E-33 T 14-10-2018 Tharo_2827 f2f33417b146c715ae0491435d36868c 616 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 610 45.119 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Tharo_2827 f2f33417b146c715ae0491435d36868c 616 SUPERFAMILY SSF52016 421 611 2.12E-60 T 14-10-2018 Tharo_2827 f2f33417b146c715ae0491435d36868c 616 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 610 1.5E-254 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Tharo_2827 f2f33417b146c715ae0491435d36868c 616 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 509 520 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Tharo_2827 f2f33417b146c715ae0491435d36868c 616 Gene3D G3DSA:3.50.30.80 421 573 1.7E-54 T 14-10-2018 Tharo_2827 f2f33417b146c715ae0491435d36868c 616 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Tharo_2827 f2f33417b146c715ae0491435d36868c 616 SUPERFAMILY SSF143975 4 420 1.96E-135 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Tharo_2827 f2f33417b146c715ae0491435d36868c 616 Pfam PF00920 Dehydratase family 34 607 1.2E-220 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Tharo_2623 9d7dabe99400c2092050d9e23de1624f 295 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 285 5.5E-73 T 14-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_2623 9d7dabe99400c2092050d9e23de1624f 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 4.4E-80 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_2623 9d7dabe99400c2092050d9e23de1624f 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 259 277 4.4E-80 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_2623 9d7dabe99400c2092050d9e23de1624f 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 242 258 4.4E-80 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_2623 9d7dabe99400c2092050d9e23de1624f 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 4.4E-80 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_2623 9d7dabe99400c2092050d9e23de1624f 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 4.4E-80 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_2623 9d7dabe99400c2092050d9e23de1624f 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 4.4E-80 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_2623 9d7dabe99400c2092050d9e23de1624f 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 4.4E-80 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_2623 9d7dabe99400c2092050d9e23de1624f 295 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 1.3E-36 T 14-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_2623 9d7dabe99400c2092050d9e23de1624f 295 Gene3D G3DSA:3.40.50.10860 8 279 6.1E-111 T 14-10-2018 Tharo_2623 9d7dabe99400c2092050d9e23de1624f 295 SUPERFAMILY SSF51735 122 284 1.42E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_2623 9d7dabe99400c2092050d9e23de1624f 295 Gene3D G3DSA:3.40.50.720 6 262 6.1E-111 T 14-10-2018 Tharo_2623 9d7dabe99400c2092050d9e23de1624f 295 SUPERFAMILY SSF53223 1 121 6.04E-37 T 14-10-2018 Tharo_2623 9d7dabe99400c2092050d9e23de1624f 295 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 263 271 - T 14-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_2623 9d7dabe99400c2092050d9e23de1624f 295 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 286 39.138 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_1291 1f15e8aed4900e9bf3f1596178331c98 418 SUPERFAMILY SSF51905 145 310 1.1E-29 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1291 1f15e8aed4900e9bf3f1596178331c98 418 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 278 1.3E-52 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Tharo_1291 1f15e8aed4900e9bf3f1596178331c98 418 SUPERFAMILY SSF51905 1 191 1.04E-39 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1291 1f15e8aed4900e9bf3f1596178331c98 418 Gene3D G3DSA:3.50.50.60 7 308 6.0E-84 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1291 1f15e8aed4900e9bf3f1596178331c98 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 104 113 3.6E-14 T 14-10-2018 Tharo_1291 1f15e8aed4900e9bf3f1596178331c98 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 232 246 3.6E-14 T 14-10-2018 Tharo_1291 1f15e8aed4900e9bf3f1596178331c98 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 3.6E-14 T 14-10-2018 Tharo_1291 1f15e8aed4900e9bf3f1596178331c98 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 271 278 3.6E-14 T 14-10-2018 Tharo_1291 1f15e8aed4900e9bf3f1596178331c98 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 9.2E-18 T 14-10-2018 Tharo_1291 1f15e8aed4900e9bf3f1596178331c98 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 9.2E-18 T 14-10-2018 Tharo_1291 1f15e8aed4900e9bf3f1596178331c98 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 9.2E-18 T 14-10-2018 Tharo_1291 1f15e8aed4900e9bf3f1596178331c98 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 278 9.2E-18 T 14-10-2018 Tharo_1291 1f15e8aed4900e9bf3f1596178331c98 418 Gene3D G3DSA:3.50.50.60 114 238 6.0E-84 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_3038 d99c154a677dfd8026a110110b402d68 544 Pfam PF00082 Subtilase family 179 432 4.7E-40 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Tharo_3038 d99c154a677dfd8026a110110b402d68 544 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 182 193 - T 14-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site Tharo_3038 d99c154a677dfd8026a110110b402d68 544 Gene3D G3DSA:3.40.50.200 131 458 5.1E-84 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 Tharo_3038 d99c154a677dfd8026a110110b402d68 544 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 394 404 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site Tharo_3038 d99c154a677dfd8026a110110b402d68 544 PRINTS PR00723 Subtilisin serine protease family (S8) signature 393 409 1.8E-16 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Tharo_3038 d99c154a677dfd8026a110110b402d68 544 PRINTS PR00723 Subtilisin serine protease family (S8) signature 177 196 1.8E-16 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Tharo_3038 d99c154a677dfd8026a110110b402d68 544 PRINTS PR00723 Subtilisin serine protease family (S8) signature 214 227 1.8E-16 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Tharo_3038 d99c154a677dfd8026a110110b402d68 544 SUPERFAMILY SSF52743 162 456 3.53E-73 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 Tharo_0819 4a80947ef22731268e6a81540a844549 426 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 42 380 3.2E-24 T 14-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Tharo_0819 4a80947ef22731268e6a81540a844549 426 SUPERFAMILY SSF50621 266 423 1.67E-51 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Tharo_0819 4a80947ef22731268e6a81540a844549 426 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 380 393 1.4E-24 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Tharo_0819 4a80947ef22731268e6a81540a844549 426 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 282 301 1.4E-24 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Tharo_0819 4a80947ef22731268e6a81540a844549 426 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 202 215 1.4E-24 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Tharo_0819 4a80947ef22731268e6a81540a844549 426 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 89 101 1.4E-24 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Tharo_0819 4a80947ef22731268e6a81540a844549 426 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 69 87 1.4E-24 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Tharo_0819 4a80947ef22731268e6a81540a844549 426 Gene3D G3DSA:2.40.37.10 30 419 2.3E-146 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Tharo_0819 4a80947ef22731268e6a81540a844549 426 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 48 291 9.1E-67 T 14-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Tharo_0819 4a80947ef22731268e6a81540a844549 426 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 18 422 8.6E-155 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Tharo_0819 4a80947ef22731268e6a81540a844549 426 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 237 253 - T 14-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site Tharo_0819 4a80947ef22731268e6a81540a844549 426 PRINTS PR01181 Diaminopimelate decarboxylase signature 176 185 2.8E-29 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Tharo_0819 4a80947ef22731268e6a81540a844549 426 PRINTS PR01181 Diaminopimelate decarboxylase signature 87 104 2.8E-29 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Tharo_0819 4a80947ef22731268e6a81540a844549 426 PRINTS PR01181 Diaminopimelate decarboxylase signature 310 328 2.8E-29 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Tharo_0819 4a80947ef22731268e6a81540a844549 426 PRINTS PR01181 Diaminopimelate decarboxylase signature 390 412 2.8E-29 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Tharo_0819 4a80947ef22731268e6a81540a844549 426 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 27 423 41.414 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Tharo_0819 4a80947ef22731268e6a81540a844549 426 Gene3D G3DSA:3.20.20.10 46 287 2.3E-146 T 14-10-2018 IPR029066 PLP-binding barrel Tharo_0819 4a80947ef22731268e6a81540a844549 426 SUPERFAMILY SSF51419 38 294 2.62E-77 T 14-10-2018 IPR029066 PLP-binding barrel Tharo_0041 6ccddd54e422fc5fd280bd73e4ff9b2f 287 PRINTS PR00721 Stomatin signature 76 97 1.0E-26 T 14-10-2018 IPR001972 Stomatin family GO:0016020 Tharo_0041 6ccddd54e422fc5fd280bd73e4ff9b2f 287 PRINTS PR00721 Stomatin signature 131 154 1.0E-26 T 14-10-2018 IPR001972 Stomatin family GO:0016020 Tharo_0041 6ccddd54e422fc5fd280bd73e4ff9b2f 287 PRINTS PR00721 Stomatin signature 111 128 1.0E-26 T 14-10-2018 IPR001972 Stomatin family GO:0016020 Tharo_0041 6ccddd54e422fc5fd280bd73e4ff9b2f 287 PRINTS PR00721 Stomatin signature 28 50 1.0E-26 T 14-10-2018 IPR001972 Stomatin family GO:0016020 Tharo_0041 6ccddd54e422fc5fd280bd73e4ff9b2f 287 PRINTS PR00721 Stomatin signature 155 173 1.0E-26 T 14-10-2018 IPR001972 Stomatin family GO:0016020 Tharo_0041 6ccddd54e422fc5fd280bd73e4ff9b2f 287 PRINTS PR00721 Stomatin signature 174 195 1.0E-26 T 14-10-2018 IPR001972 Stomatin family GO:0016020 Tharo_0041 6ccddd54e422fc5fd280bd73e4ff9b2f 287 Pfam PF01145 SPFH domain / Band 7 family 26 194 2.1E-30 T 14-10-2018 IPR001107 Band 7 domain Tharo_0041 6ccddd54e422fc5fd280bd73e4ff9b2f 287 SMART SM00244 21 179 3.3E-52 T 14-10-2018 IPR001107 Band 7 domain Tharo_0041 6ccddd54e422fc5fd280bd73e4ff9b2f 287 Gene3D G3DSA:3.30.479.30 49 181 1.4E-37 T 14-10-2018 Tharo_0041 6ccddd54e422fc5fd280bd73e4ff9b2f 287 SUPERFAMILY SSF117892 52 185 2.48E-37 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily Tharo_0521 bb4b56731b90f4fbc5655d79b3777d53 247 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 3 221 8.6E-26 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 Tharo_0521 bb4b56731b90f4fbc5655d79b3777d53 247 Pfam PF03309 Type III pantothenate kinase 2 198 3.8E-56 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 Tharo_0521 bb4b56731b90f4fbc5655d79b3777d53 247 Gene3D G3DSA:3.30.420.40 3 237 1.1E-67 T 14-10-2018 Tharo_0521 bb4b56731b90f4fbc5655d79b3777d53 247 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 245 19.012 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 Tharo_0521 bb4b56731b90f4fbc5655d79b3777d53 247 SUPERFAMILY SSF53067 119 240 2.16E-28 T 14-10-2018 Tharo_0521 bb4b56731b90f4fbc5655d79b3777d53 247 SUPERFAMILY SSF53067 1 117 4.14E-23 T 14-10-2018 Tharo_0521 bb4b56731b90f4fbc5655d79b3777d53 247 Gene3D G3DSA:3.30.420.490 120 233 1.1E-67 T 14-10-2018 Tharo_2087 c7bf1b13341dac0f0de03dd04e9e1dce 403 Gene3D G3DSA:3.90.1150.10 6 374 2.8E-164 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_2087 c7bf1b13341dac0f0de03dd04e9e1dce 403 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 2 394 54.968 T 14-10-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 Tharo_2087 c7bf1b13341dac0f0de03dd04e9e1dce 403 Pfam PF00266 Aminotransferase class-V 6 367 7.3E-90 T 14-10-2018 IPR000192 Aminotransferase class V domain Tharo_2087 c7bf1b13341dac0f0de03dd04e9e1dce 403 Gene3D G3DSA:3.40.640.10 17 261 2.8E-164 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_2087 c7bf1b13341dac0f0de03dd04e9e1dce 403 TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS 2 403 8.9E-229 T 14-10-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 Tharo_2087 c7bf1b13341dac0f0de03dd04e9e1dce 403 SUPERFAMILY SSF53383 5 390 1.05E-114 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_2087 c7bf1b13341dac0f0de03dd04e9e1dce 403 PIRSF PIRSF005572 3 383 1.2E-137 T 14-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 Tharo_2087 c7bf1b13341dac0f0de03dd04e9e1dce 403 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 196 215 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site Tharo_1300 ab858429868976bc7555be5fc18645b1 279 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 22 270 3.0E-84 T 14-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate Tharo_1300 ab858429868976bc7555be5fc18645b1 279 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 56 203 5.9E-31 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Tharo_1300 ab858429868976bc7555be5fc18645b1 279 SUPERFAMILY SSF52518 19 267 1.89E-74 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_1300 ab858429868976bc7555be5fc18645b1 279 Gene3D G3DSA:3.40.50.970 84 227 2.0E-25 T 14-10-2018 Tharo_0217 6a408701f173e49b183ea0489f37b320 127 SUPERFAMILY SSF50118 9 123 2.4E-23 T 14-10-2018 Tharo_0217 6a408701f173e49b183ea0489f37b320 127 Gene3D G3DSA:2.30.30.110 7 127 3.6E-27 T 14-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor Tharo_0217 6a408701f173e49b183ea0489f37b320 127 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 14 121 1.4E-16 T 14-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 Tharo_2297 c22ba7ae0f31fd948c822e5d92f44591 211 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 9 188 3.6E-81 T 14-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO Tharo_2297 c22ba7ae0f31fd948c822e5d92f44591 211 Gene3D G3DSA:1.10.760.10 50 211 5.4E-68 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_2297 c22ba7ae0f31fd948c822e5d92f44591 211 SUPERFAMILY SSF46626 17 203 2.66E-26 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_2297 c22ba7ae0f31fd948c822e5d92f44591 211 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 6 186 3.0E-74 T 14-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO Tharo_1017 5c5233c3c6ff9398096af9c9be3ab316 121 SMART SM00448 1 112 2.5E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1017 5c5233c3c6ff9398096af9c9be3ab316 121 SUPERFAMILY SSF52172 2 116 8.82E-24 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1017 5c5233c3c6ff9398096af9c9be3ab316 121 Pfam PF00072 Response regulator receiver domain 3 106 1.7E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1017 5c5233c3c6ff9398096af9c9be3ab316 121 Gene3D G3DSA:3.40.50.2300 1 121 4.9E-23 T 14-10-2018 Tharo_1290 15201b0ba0039d90d4cf22ee55f5fa1a 450 Gene3D G3DSA:3.30.70.20 69 122 1.1E-21 T 14-10-2018 Tharo_1290 15201b0ba0039d90d4cf22ee55f5fa1a 450 Pfam PF13247 4Fe-4S dicluster domain 61 143 7.4E-11 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_1290 15201b0ba0039d90d4cf22ee55f5fa1a 450 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 214 358 3.0E-18 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Tharo_1290 15201b0ba0039d90d4cf22ee55f5fa1a 450 Gene3D G3DSA:3.30.70.20 8 145 1.1E-21 T 14-10-2018 Tharo_1290 15201b0ba0039d90d4cf22ee55f5fa1a 450 Pfam PF12837 4Fe-4S binding domain 8 25 5.1E-6 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_1290 15201b0ba0039d90d4cf22ee55f5fa1a 450 Gene3D G3DSA:3.40.50.970 207 448 5.9E-58 T 14-10-2018 Tharo_1290 15201b0ba0039d90d4cf22ee55f5fa1a 450 SUPERFAMILY SSF52518 150 442 4.91E-63 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_1290 15201b0ba0039d90d4cf22ee55f5fa1a 450 SUPERFAMILY SSF54862 7 159 6.87E-33 T 14-10-2018 Tharo_3430 0ca6a78b1ba86dbe956614d7fee9a39b 131 SUPERFAMILY SSF88723 1 119 6.45E-15 T 14-10-2018 IPR029060 PIN-like domain superfamily Tharo_3430 0ca6a78b1ba86dbe956614d7fee9a39b 131 Pfam PF01850 PIN domain 4 116 2.4E-6 T 14-10-2018 IPR002716 PIN domain Tharo_1444 4d22f86cbd86135b1a503a767378f44a 433 TIGRFAM TIGR04247 NosD_copper_fam: nitrous oxide reductase family maturation protein NosD 42 414 7.1E-135 T 14-10-2018 IPR026464 Nitrous oxide reductase family maturation protein NosD Tharo_1444 4d22f86cbd86135b1a503a767378f44a 433 Gene3D G3DSA:2.160.20.10 25 287 1.7E-25 T 14-10-2018 IPR012334 Pectin lyase fold Tharo_1444 4d22f86cbd86135b1a503a767378f44a 433 Pfam PF05048 Periplasmic copper-binding protein (NosD) 154 378 5.3E-62 T 14-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 Tharo_1444 4d22f86cbd86135b1a503a767378f44a 433 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 260 302 4.9E-9 T 14-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 Tharo_1444 4d22f86cbd86135b1a503a767378f44a 433 SMART SM00722 203 362 3.0E-4 T 14-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain Tharo_1444 4d22f86cbd86135b1a503a767378f44a 433 SMART SM00722 49 197 1.2E-8 T 14-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain Tharo_1444 4d22f86cbd86135b1a503a767378f44a 433 SUPERFAMILY SSF51126 36 401 3.84E-65 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor Tharo_1444 4d22f86cbd86135b1a503a767378f44a 433 SMART SM00710 95 123 12.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat Tharo_1444 4d22f86cbd86135b1a503a767378f44a 433 SMART SM00710 243 265 9.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat Tharo_1444 4d22f86cbd86135b1a503a767378f44a 433 SMART SM00710 125 146 1500.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat Tharo_1444 4d22f86cbd86135b1a503a767378f44a 433 SMART SM00710 177 198 2100.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat Tharo_1444 4d22f86cbd86135b1a503a767378f44a 433 SMART SM00710 311 348 4000.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat Tharo_1444 4d22f86cbd86135b1a503a767378f44a 433 SMART SM00710 199 220 2000.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat Tharo_1444 4d22f86cbd86135b1a503a767378f44a 433 SMART SM00710 288 309 12.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat Tharo_1444 4d22f86cbd86135b1a503a767378f44a 433 SMART SM00710 266 287 27.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat Tharo_1444 4d22f86cbd86135b1a503a767378f44a 433 SMART SM00710 147 176 53.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat Tharo_1603 5fa6b1b459c1577019f3348c2f976912 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Tharo_1603 5fa6b1b459c1577019f3348c2f976912 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1603 5fa6b1b459c1577019f3348c2f976912 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1603 5fa6b1b459c1577019f3348c2f976912 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1603 5fa6b1b459c1577019f3348c2f976912 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 191 1.3E-5 T 14-10-2018 Tharo_1603 5fa6b1b459c1577019f3348c2f976912 249 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 10 247 3.6E-101 T 14-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Tharo_1603 5fa6b1b459c1577019f3348c2f976912 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.5E-49 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1603 5fa6b1b459c1577019f3348c2f976912 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 5.5E-49 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1603 5fa6b1b459c1577019f3348c2f976912 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 5.5E-49 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1603 5fa6b1b459c1577019f3348c2f976912 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 5.5E-49 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1603 5fa6b1b459c1577019f3348c2f976912 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 5.5E-49 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1603 5fa6b1b459c1577019f3348c2f976912 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 5.5E-49 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1603 5fa6b1b459c1577019f3348c2f976912 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 246 1.2E-69 T 14-10-2018 Tharo_1603 5fa6b1b459c1577019f3348c2f976912 249 Gene3D G3DSA:3.40.50.720 1 248 1.0E-87 T 14-10-2018 Tharo_1603 5fa6b1b459c1577019f3348c2f976912 249 SUPERFAMILY SSF51735 6 248 2.55E-88 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 Gene3D G3DSA:3.20.20.450 558 807 9.0E-94 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 Gene3D G3DSA:3.30.450.20 268 380 1.2E-21 T 14-10-2018 Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 SMART SM00086 88 131 15.0 T 14-10-2018 IPR001610 PAC motif Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 SMART SM00086 334 372 0.036 T 14-10-2018 IPR001610 PAC motif Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 SMART SM00086 216 258 5.4E-5 T 14-10-2018 IPR001610 PAC motif Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 SUPERFAMILY SSF55785 12 129 1.59E-19 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 SUPERFAMILY SSF55073 388 546 1.73E-51 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 Pfam PF08448 PAS fold 22 132 1.1E-22 T 14-10-2018 IPR013656 PAS fold-4 Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 SUPERFAMILY SSF141868 561 808 7.59E-85 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 381 544 2.6E-42 T 14-10-2018 IPR000160 GGDEF domain Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 139 263 1.4E-23 T 14-10-2018 IPR000014 PAS domain Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 17 137 1.6E-14 T 14-10-2018 IPR000014 PAS domain Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 263 379 4.7E-16 T 14-10-2018 IPR000014 PAS domain Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 Pfam PF00989 PAS fold 146 255 9.1E-18 T 14-10-2018 IPR013767 PAS fold GO:0006355 Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 Pfam PF00989 PAS fold 267 369 7.6E-12 T 14-10-2018 IPR013767 PAS fold GO:0006355 Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 SMART SM00052 554 800 4.6E-108 T 14-10-2018 IPR001633 EAL domain Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 Gene3D G3DSA:3.30.450.20 8 140 1.1E-27 T 14-10-2018 Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 SMART SM00091 143 209 1.3E-12 T 14-10-2018 IPR000014 PAS domain Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 SMART SM00091 263 329 2.2E-7 T 14-10-2018 IPR000014 PAS domain Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 SMART SM00091 16 82 2.6E-5 T 14-10-2018 IPR000014 PAS domain Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 SUPERFAMILY SSF55785 128 256 1.57E-30 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 Gene3D G3DSA:3.30.70.270 381 557 3.1E-59 T 14-10-2018 Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 SUPERFAMILY SSF55785 274 380 9.95E-20 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 Pfam PF00990 Diguanylate cyclase, GGDEF domain 383 540 7.1E-47 T 14-10-2018 IPR000160 GGDEF domain Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 Gene3D G3DSA:3.30.450.20 141 267 1.6E-23 T 14-10-2018 Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 SMART SM00267 372 544 1.1E-65 T 14-10-2018 IPR000160 GGDEF domain Tharo_3175 92c1ee523b3ab8fc5b7f17da4e3ce274 815 Pfam PF00563 EAL domain 560 795 6.7E-70 T 14-10-2018 IPR001633 EAL domain Tharo_0531 ddb356e67dee156bfe52ce33bfdb45a7 384 Gene3D G3DSA:3.30.870.10 197 342 1.7E-26 T 14-10-2018 Tharo_0531 ddb356e67dee156bfe52ce33bfdb45a7 384 Hamap MF_01917 Cardiolipin synthase B [clsB]. 1 384 46.601 T 14-10-2018 IPR030872 Cardiolipin synthase B GO:0008808|GO:0032049 Tharo_0531 ddb356e67dee156bfe52ce33bfdb45a7 384 SUPERFAMILY SSF56024 3 182 7.33E-41 T 14-10-2018 Tharo_0531 ddb356e67dee156bfe52ce33bfdb45a7 384 Gene3D G3DSA:3.30.870.10 4 180 9.2E-39 T 14-10-2018 Tharo_0531 ddb356e67dee156bfe52ce33bfdb45a7 384 SMART SM00155 286 313 5.1 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 Tharo_0531 ddb356e67dee156bfe52ce33bfdb45a7 384 SMART SM00155 106 133 3.5E-4 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 Tharo_0531 ddb356e67dee156bfe52ce33bfdb45a7 384 SUPERFAMILY SSF56024 179 356 9.87E-39 T 14-10-2018 Tharo_0531 ddb356e67dee156bfe52ce33bfdb45a7 384 Pfam PF13091 PLD-like domain 214 338 4.6E-23 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 Tharo_0531 ddb356e67dee156bfe52ce33bfdb45a7 384 Pfam PF13091 PLD-like domain 24 129 4.4E-14 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 Tharo_3279 fbcb9c21ecab4b8af5b0c28d9ed33925 223 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 30 191 1.0E-33 T 14-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain Tharo_3279 fbcb9c21ecab4b8af5b0c28d9ed33925 223 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 3 210 4.7E-82 T 14-10-2018 IPR004392 Hydrogenase maturation factor HypB GO:0016151|GO:0051604 Tharo_3279 fbcb9c21ecab4b8af5b0c28d9ed33925 223 SUPERFAMILY SSF52540 20 210 1.26E-32 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3279 fbcb9c21ecab4b8af5b0c28d9ed33925 223 Gene3D G3DSA:3.40.50.300 10 216 5.9E-62 T 14-10-2018 Tharo_3279 fbcb9c21ecab4b8af5b0c28d9ed33925 223 PIRSF PIRSF005624 1 222 3.9E-90 T 14-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 Tharo_2885 7cc40aa287562ae88bbc7caa7421e31a 239 Pfam PF10108 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB 172 234 1.8E-5 T 14-10-2018 IPR019288 Predicted 3'-5' exonuclease, PolB-like Tharo_2885 7cc40aa287562ae88bbc7caa7421e31a 239 SUPERFAMILY SSF53098 56 233 1.0E-15 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_2885 7cc40aa287562ae88bbc7caa7421e31a 239 Gene3D G3DSA:3.30.420.10 1 197 1.2E-6 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_2695 879ab35655f5ecbd95b84607b1c6c74e 402 SUPERFAMILY SSF103473 9 392 7.19E-56 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_2695 879ab35655f5ecbd95b84607b1c6c74e 402 Pfam PF07690 Major Facilitator Superfamily 23 346 1.5E-33 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_2695 879ab35655f5ecbd95b84607b1c6c74e 402 Gene3D G3DSA:1.20.1250.20 8 391 3.2E-76 T 14-10-2018 Tharo_1136 7ff001323a18056c198977db5c64fbc4 525 Gene3D G3DSA:3.40.605.10 9 487 4.0E-151 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Tharo_1136 7ff001323a18056c198977db5c64fbc4 525 SUPERFAMILY SSF53720 5 502 1.44E-78 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Tharo_1136 7ff001323a18056c198977db5c64fbc4 525 Pfam PF00171 Aldehyde dehydrogenase family 11 446 4.0E-64 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Tharo_1136 7ff001323a18056c198977db5c64fbc4 525 TIGRFAM TIGR02278 PaaN-DH: phenylacetic acid degradation protein paaN 4 517 1.0E-171 T 14-10-2018 IPR011966 Phenylacetic acid degradation protein PaaN KEGG: 00360+3.3.2.12+1.2.1.91 Tharo_1136 7ff001323a18056c198977db5c64fbc4 525 Gene3D G3DSA:3.40.309.10 258 475 4.0E-151 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Tharo_2848 b0d7c58393197c97504a3c7b79f4b814 801 Gene3D G3DSA:2.170.130.10 146 267 4.2E-39 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Tharo_2848 b0d7c58393197c97504a3c7b79f4b814 801 Pfam PF07715 TonB-dependent Receptor Plug Domain 162 258 3.6E-21 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain Tharo_2848 b0d7c58393197c97504a3c7b79f4b814 801 Gene3D G3DSA:2.40.170.20 268 801 3.4E-122 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Tharo_2848 b0d7c58393197c97504a3c7b79f4b814 801 SUPERFAMILY SSF56935 126 801 4.35E-136 T 14-10-2018 Tharo_2848 b0d7c58393197c97504a3c7b79f4b814 801 Pfam PF07660 Secretin and TonB N terminus short domain 74 122 9.3E-7 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 Tharo_2848 b0d7c58393197c97504a3c7b79f4b814 801 SMART SM00965 73 123 1.0E-10 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 Tharo_2848 b0d7c58393197c97504a3c7b79f4b814 801 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 164 801 7.5E-113 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 Tharo_2848 b0d7c58393197c97504a3c7b79f4b814 801 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 784 801 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site Tharo_2848 b0d7c58393197c97504a3c7b79f4b814 801 Pfam PF00593 TonB dependent receptor 358 800 6.8E-57 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Tharo_2848 b0d7c58393197c97504a3c7b79f4b814 801 Gene3D G3DSA:3.55.50.30 43 145 3.3E-20 T 14-10-2018 Tharo_0913 da61bda10385b93ddca54f2a78faf670 345 SUPERFAMILY SSF51556 1 342 6.05E-142 T 14-10-2018 IPR032466 Metal-dependent hydrolase Tharo_0913 da61bda10385b93ddca54f2a78faf670 345 Hamap MF_00219 Dihydroorotase [pyrC]. 2 343 47.785 T 14-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_0913 da61bda10385b93ddca54f2a78faf670 345 ProSitePatterns PS00483 Dihydroorotase signature 2. 244 255 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_0913 da61bda10385b93ddca54f2a78faf670 345 Gene3D G3DSA:3.20.20.140 2 343 7.3E-110 T 14-10-2018 Tharo_0913 da61bda10385b93ddca54f2a78faf670 345 PIRSF PIRSF001237 1 345 6.6E-142 T 14-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_0913 da61bda10385b93ddca54f2a78faf670 345 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 4 342 6.3E-142 T 14-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_0913 da61bda10385b93ddca54f2a78faf670 345 Pfam PF01979 Amidohydrolase family 11 304 7.4E-18 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Tharo_2704 b05b1a26f9ab644ccb987d0d7de448e1 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 267 286 8.6E-95 T 14-10-2018 Tharo_2704 b05b1a26f9ab644ccb987d0d7de448e1 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 114 137 8.6E-95 T 14-10-2018 Tharo_2704 b05b1a26f9ab644ccb987d0d7de448e1 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 365 383 8.6E-95 T 14-10-2018 Tharo_2704 b05b1a26f9ab644ccb987d0d7de448e1 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 149 174 8.6E-95 T 14-10-2018 Tharo_2704 b05b1a26f9ab644ccb987d0d7de448e1 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 73 93 8.6E-95 T 14-10-2018 Tharo_2704 b05b1a26f9ab644ccb987d0d7de448e1 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 175 198 8.6E-95 T 14-10-2018 Tharo_2704 b05b1a26f9ab644ccb987d0d7de448e1 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 397 415 8.6E-95 T 14-10-2018 Tharo_2704 b05b1a26f9ab644ccb987d0d7de448e1 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 310 332 8.6E-95 T 14-10-2018 Tharo_2704 b05b1a26f9ab644ccb987d0d7de448e1 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 21 39 8.6E-95 T 14-10-2018 Tharo_2704 b05b1a26f9ab644ccb987d0d7de448e1 441 ProSitePatterns PS00756 Protein secY signature 2. 168 185 - T 14-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Tharo_2704 b05b1a26f9ab644ccb987d0d7de448e1 441 PIRSF PIRSF004557 8 435 1.2E-122 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Tharo_2704 b05b1a26f9ab644ccb987d0d7de448e1 441 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 18 424 3.9E-132 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Tharo_2704 b05b1a26f9ab644ccb987d0d7de448e1 441 ProSitePatterns PS00755 Protein secY signature 1. 74 93 - T 14-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Tharo_2704 b05b1a26f9ab644ccb987d0d7de448e1 441 Gene3D G3DSA:1.10.3370.10 7 424 1.9E-163 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Tharo_2704 b05b1a26f9ab644ccb987d0d7de448e1 441 Pfam PF00344 SecY translocase 74 412 1.8E-118 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Tharo_2704 b05b1a26f9ab644ccb987d0d7de448e1 441 Hamap MF_01465 Protein translocase subunit SecY [secY]. 8 428 29.881 T 14-10-2018 IPR026593 Protein translocase subunit SecY Tharo_2704 b05b1a26f9ab644ccb987d0d7de448e1 441 SUPERFAMILY SSF103491 12 418 2.35E-132 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Tharo_1796 0d6dee427af40fce15a62421df9ff267 346 Gene3D G3DSA:3.90.650.10 162 345 3.0E-50 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Tharo_1796 0d6dee427af40fce15a62421df9ff267 346 SUPERFAMILY SSF56042 162 340 1.38E-46 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Tharo_1796 0d6dee427af40fce15a62421df9ff267 346 Hamap MF_00625 Selenide, water dikinase [selD]. 3 346 41.675 T 14-10-2018 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 Tharo_1796 0d6dee427af40fce15a62421df9ff267 346 TIGRFAM TIGR00476 selD: selenide, water dikinase 5 314 1.1E-126 T 14-10-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 Tharo_1796 0d6dee427af40fce15a62421df9ff267 346 SUPERFAMILY SSF55326 6 158 2.22E-38 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Tharo_1796 0d6dee427af40fce15a62421df9ff267 346 Gene3D G3DSA:3.30.1330.10 1 160 1.5E-45 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Tharo_1796 0d6dee427af40fce15a62421df9ff267 346 PIRSF PIRSF036407 1 346 5.1E-113 T 14-10-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 Tharo_1796 0d6dee427af40fce15a62421df9ff267 346 Pfam PF00586 AIR synthase related protein, N-terminal domain 48 155 9.9E-19 T 14-10-2018 IPR016188 PurM-like, N-terminal domain Tharo_1796 0d6dee427af40fce15a62421df9ff267 346 Pfam PF02769 AIR synthase related protein, C-terminal domain 168 341 5.7E-28 T 14-10-2018 IPR010918 PurM-like, C-terminal domain Tharo_2983 bbc4602cbe182733b99720f4e6821805 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.5E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2983 bbc4602cbe182733b99720f4e6821805 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 1.5E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2983 bbc4602cbe182733b99720f4e6821805 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.5E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2983 bbc4602cbe182733b99720f4e6821805 251 Gene3D G3DSA:3.40.50.720 9 249 7.3E-63 T 14-10-2018 Tharo_2983 bbc4602cbe182733b99720f4e6821805 251 SUPERFAMILY SSF51735 12 249 8.54E-66 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_2983 bbc4602cbe182733b99720f4e6821805 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Tharo_2983 bbc4602cbe182733b99720f4e6821805 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 246 7.2E-50 T 14-10-2018 Tharo_2983 bbc4602cbe182733b99720f4e6821805 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 4.2E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2983 bbc4602cbe182733b99720f4e6821805 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 4.2E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2983 bbc4602cbe182733b99720f4e6821805 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 4.2E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2983 bbc4602cbe182733b99720f4e6821805 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 4.2E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2983 bbc4602cbe182733b99720f4e6821805 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 4.2E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2983 bbc4602cbe182733b99720f4e6821805 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 4.2E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3240 a49d24f067f25797ded87ec59bef8251 194 Gene3D G3DSA:3.90.350.10 62 184 1.7E-22 T 14-10-2018 IPR014736 Transposase, Tn5-like, core Tharo_3240 a49d24f067f25797ded87ec59bef8251 194 SUPERFAMILY SSF53098 2 183 1.82E-44 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_3240 a49d24f067f25797ded87ec59bef8251 194 Pfam PF14706 Transposase DNA-binding 2 59 5.8E-24 T 14-10-2018 IPR014735 Transposase, Tn5-like, N-terminal Tharo_3240 a49d24f067f25797ded87ec59bef8251 194 Gene3D G3DSA:1.10.246.40 1 59 1.8E-10 T 14-10-2018 IPR038215 Transposase, Tn5-like, N-terminal domain superfamily Tharo_0744 f7cd288c5b862bb9cb8720c58e9f4297 192 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 41 55 4.9E-6 T 14-10-2018 Tharo_0744 f7cd288c5b862bb9cb8720c58e9f4297 192 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 71 87 4.9E-6 T 14-10-2018 Tharo_0744 f7cd288c5b862bb9cb8720c58e9f4297 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 161 174 3.2E-13 T 14-10-2018 Tharo_0744 f7cd288c5b862bb9cb8720c58e9f4297 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 71 82 3.2E-13 T 14-10-2018 Tharo_0744 f7cd288c5b862bb9cb8720c58e9f4297 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 44 53 3.2E-13 T 14-10-2018 Tharo_0744 f7cd288c5b862bb9cb8720c58e9f4297 192 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 184 2.4E-83 T 14-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Tharo_0744 f7cd288c5b862bb9cb8720c58e9f4297 192 Pfam PF00117 Glutamine amidotransferase class-I 1 182 4.5E-54 T 14-10-2018 IPR017926 Glutamine amidotransferase Tharo_0744 f7cd288c5b862bb9cb8720c58e9f4297 192 PRINTS PR00097 Anthranilate synthase component II signature 161 174 5.0E-27 T 14-10-2018 Tharo_0744 f7cd288c5b862bb9cb8720c58e9f4297 192 PRINTS PR00097 Anthranilate synthase component II signature 116 128 5.0E-27 T 14-10-2018 Tharo_0744 f7cd288c5b862bb9cb8720c58e9f4297 192 PRINTS PR00097 Anthranilate synthase component II signature 71 82 5.0E-27 T 14-10-2018 Tharo_0744 f7cd288c5b862bb9cb8720c58e9f4297 192 PRINTS PR00097 Anthranilate synthase component II signature 96 104 5.0E-27 T 14-10-2018 Tharo_0744 f7cd288c5b862bb9cb8720c58e9f4297 192 PRINTS PR00097 Anthranilate synthase component II signature 44 53 5.0E-27 T 14-10-2018 Tharo_0744 f7cd288c5b862bb9cb8720c58e9f4297 192 SUPERFAMILY SSF52317 1 184 1.22E-55 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Tharo_0744 f7cd288c5b862bb9cb8720c58e9f4297 192 Gene3D G3DSA:3.40.50.880 1 187 2.7E-61 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Tharo_3388 908cedf83280ce50fb4911a38be93719 467 Gene3D G3DSA:3.30.70.1450 366 467 2.4E-30 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Tharo_3388 908cedf83280ce50fb4911a38be93719 467 SUPERFAMILY SSF116726 362 455 1.83E-8 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Tharo_3388 908cedf83280ce50fb4911a38be93719 467 SUPERFAMILY SSF116726 135 222 5.36E-9 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Tharo_3388 908cedf83280ce50fb4911a38be93719 467 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 2.2E-24 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Tharo_3388 908cedf83280ce50fb4911a38be93719 467 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 2.2E-24 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Tharo_3388 908cedf83280ce50fb4911a38be93719 467 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 2.2E-24 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Tharo_3388 908cedf83280ce50fb4911a38be93719 467 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 2.2E-24 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Tharo_3388 908cedf83280ce50fb4911a38be93719 467 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 2.2E-24 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Tharo_3388 908cedf83280ce50fb4911a38be93719 467 Pfam PF02254 TrkA-N domain 3 106 1.2E-24 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Tharo_3388 908cedf83280ce50fb4911a38be93719 467 Pfam PF02254 TrkA-N domain 234 349 2.4E-21 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Tharo_3388 908cedf83280ce50fb4911a38be93719 467 Gene3D G3DSA:3.40.50.720 2 138 1.3E-41 T 14-10-2018 Tharo_3388 908cedf83280ce50fb4911a38be93719 467 Pfam PF02080 TrkA-C domain 389 460 2.2E-11 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Tharo_3388 908cedf83280ce50fb4911a38be93719 467 Pfam PF02080 TrkA-C domain 161 223 7.9E-9 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Tharo_3388 908cedf83280ce50fb4911a38be93719 467 Gene3D G3DSA:3.40.50.720 232 365 2.2E-33 T 14-10-2018 Tharo_3388 908cedf83280ce50fb4911a38be93719 467 SUPERFAMILY SSF51735 2 150 1.3E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_3388 908cedf83280ce50fb4911a38be93719 467 SUPERFAMILY SSF51735 232 375 2.96E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_3388 908cedf83280ce50fb4911a38be93719 467 Gene3D G3DSA:3.30.70.1450 139 230 2.2E-19 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Tharo_3091 36dc1ef3ea385c51eb5991c147d2567e 305 Pfam PF01062 Bestrophin, RFP-TM, chloride channel 2 282 4.4E-60 T 14-10-2018 IPR021134 Bestrophin/UPF0187 Reactome: R-HSA-2672351 Tharo_2681 62e1399d094e248d26f365574da049f5 288 Gene3D G3DSA:3.40.50.720 1 160 2.6E-49 T 14-10-2018 Tharo_2681 62e1399d094e248d26f365574da049f5 288 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 14-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 Tharo_2681 62e1399d094e248d26f365574da049f5 288 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 160 2.4E-46 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 Tharo_2681 62e1399d094e248d26f365574da049f5 288 SUPERFAMILY SSF48179 161 284 1.25E-34 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Tharo_2681 62e1399d094e248d26f365574da049f5 288 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 163 283 1.6E-28 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 Tharo_2681 62e1399d094e248d26f365574da049f5 288 Gene3D G3DSA:1.10.1040.10 161 288 2.1E-35 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Tharo_2681 62e1399d094e248d26f365574da049f5 288 PIRSF PIRSF000103 1 288 2.5E-73 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 Tharo_2681 62e1399d094e248d26f365574da049f5 288 SUPERFAMILY SSF51735 1 161 5.92E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_2969 75487b9ed1ffdb663c3343c8c16d2b0f 472 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 9 470 6.7E-140 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Tharo_2969 75487b9ed1ffdb663c3343c8c16d2b0f 472 Gene3D G3DSA:1.10.10.60 413 470 2.8E-22 T 14-10-2018 Tharo_2969 75487b9ed1ffdb663c3343c8c16d2b0f 472 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 360 379 - T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Tharo_2969 75487b9ed1ffdb663c3343c8c16d2b0f 472 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 451 458 - T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Tharo_2969 75487b9ed1ffdb663c3343c8c16d2b0f 472 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 4 48 4.3E-17 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Tharo_2969 75487b9ed1ffdb663c3343c8c16d2b0f 472 Gene3D G3DSA:1.10.10.1330 115 256 4.9E-21 T 14-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily Tharo_2969 75487b9ed1ffdb663c3343c8c16d2b0f 472 Pfam PF04552 Sigma-54, DNA binding domain 317 470 2.6E-66 T 14-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding Tharo_2969 75487b9ed1ffdb663c3343c8c16d2b0f 472 Pfam PF04963 Sigma-54 factor, core binding domain 108 301 5.8E-56 T 14-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 Tharo_2969 75487b9ed1ffdb663c3343c8c16d2b0f 472 PIRSF PIRSF000774 1 472 2.7E-153 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Tharo_2969 75487b9ed1ffdb663c3343c8c16d2b0f 472 PRINTS PR00045 Sigma-54 factor signature 372 384 1.4E-30 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Tharo_2969 75487b9ed1ffdb663c3343c8c16d2b0f 472 PRINTS PR00045 Sigma-54 factor signature 185 202 1.4E-30 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Tharo_2969 75487b9ed1ffdb663c3343c8c16d2b0f 472 PRINTS PR00045 Sigma-54 factor signature 446 464 1.4E-30 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Tharo_2969 75487b9ed1ffdb663c3343c8c16d2b0f 472 PRINTS PR00045 Sigma-54 factor signature 388 399 1.4E-30 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Tharo_1562 f04536de457b83313aefca0dd6cb668d 303 Gene3D G3DSA:3.40.1500.10 1 302 1.1E-129 T 14-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Tharo_1562 f04536de457b83313aefca0dd6cb668d 303 PIRSF PIRSF000166 3 303 1.5E-122 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Tharo_1562 f04536de457b83313aefca0dd6cb668d 303 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 1 277 51.98 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Tharo_1562 f04536de457b83313aefca0dd6cb668d 303 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 163 187 - T 14-10-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Tharo_1562 f04536de457b83313aefca0dd6cb668d 303 PRINTS PR00073 Coprogen oxidase signature 27 43 3.4E-84 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Tharo_1562 f04536de457b83313aefca0dd6cb668d 303 PRINTS PR00073 Coprogen oxidase signature 234 261 3.4E-84 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Tharo_1562 f04536de457b83313aefca0dd6cb668d 303 PRINTS PR00073 Coprogen oxidase signature 262 288 3.4E-84 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Tharo_1562 f04536de457b83313aefca0dd6cb668d 303 PRINTS PR00073 Coprogen oxidase signature 121 143 3.4E-84 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Tharo_1562 f04536de457b83313aefca0dd6cb668d 303 PRINTS PR00073 Coprogen oxidase signature 159 188 3.4E-84 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Tharo_1562 f04536de457b83313aefca0dd6cb668d 303 PRINTS PR00073 Coprogen oxidase signature 86 110 3.4E-84 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Tharo_1562 f04536de457b83313aefca0dd6cb668d 303 PRINTS PR00073 Coprogen oxidase signature 44 65 3.4E-84 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Tharo_1562 f04536de457b83313aefca0dd6cb668d 303 Pfam PF01218 Coproporphyrinogen III oxidase 6 301 3.0E-126 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Tharo_1562 f04536de457b83313aefca0dd6cb668d 303 SUPERFAMILY SSF102886 5 302 1.83E-130 T 14-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Tharo_3455 4ea223520f7b3ccf65b0bf322ae1118b 241 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 89 4.2E-7 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain Tharo_3455 4ea223520f7b3ccf65b0bf322ae1118b 241 SUPERFAMILY SSF52540 3 188 1.17E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3455 4ea223520f7b3ccf65b0bf322ae1118b 241 Gene3D G3DSA:3.40.50.300 2 223 4.7E-10 T 14-10-2018 Tharo_2247 898b8d7956b0025d8394b86651f9183d 337 SUPERFAMILY SSF53448 12 234 2.25E-31 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_2247 898b8d7956b0025d8394b86651f9183d 337 Pfam PF00535 Glycosyl transferase family 2 12 119 9.9E-14 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Tharo_2247 898b8d7956b0025d8394b86651f9183d 337 Gene3D G3DSA:3.90.550.10 4 257 1.4E-27 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_2461 aa88260e15b0db9931b03c8d9202331a 470 Pfam PF08245 Mur ligase middle domain 105 245 1.1E-18 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Tharo_2461 aa88260e15b0db9931b03c8d9202331a 470 Gene3D G3DSA:3.40.1190.10 81 310 2.6E-30 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Tharo_2461 aa88260e15b0db9931b03c8d9202331a 470 SUPERFAMILY SSF53623 103 307 2.14E-25 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Tharo_2026 9ad5e90ff5de439539d96c7c9bc91420 356 Gene3D G3DSA:3.40.50.720 2 321 2.8E-130 T 14-10-2018 Tharo_2026 9ad5e90ff5de439539d96c7c9bc91420 356 SUPERFAMILY SSF51735 2 346 2.82E-89 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_2026 9ad5e90ff5de439539d96c7c9bc91420 356 Pfam PF16363 GDP-mannose 4,6 dehydratase 3 322 9.7E-97 T 14-10-2018 IPR016040 NAD(P)-binding domain Tharo_2026 9ad5e90ff5de439539d96c7c9bc91420 356 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 335 4.5E-149 T 14-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 Tharo_2026 9ad5e90ff5de439539d96c7c9bc91420 356 Gene3D G3DSA:3.90.25.10 200 329 2.8E-130 T 14-10-2018 Tharo_1922 9851c9a617418ebe5510f0de56764faa 161 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 101 112 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_1922 9851c9a617418ebe5510f0de56764faa 161 Gene3D G3DSA:3.30.70.3270 35 161 1.1E-38 T 14-10-2018 Tharo_1922 9851c9a617418ebe5510f0de56764faa 161 Pfam PF12838 4Fe-4S dicluster domain 61 115 1.7E-12 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_1922 9851c9a617418ebe5510f0de56764faa 161 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 9 158 28.455 T 14-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1922 9851c9a617418ebe5510f0de56764faa 161 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 18 139 2.3E-47 T 14-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1922 9851c9a617418ebe5510f0de56764faa 161 SUPERFAMILY SSF54862 35 143 6.7E-26 T 14-10-2018 Tharo_1739 66291e3bc7cd30d8947ff24cb46f8370 521 Pfam PF02540 NAD synthase 212 250 6.8E-7 T 14-10-2018 IPR022310 NAD/GMP synthase Tharo_1739 66291e3bc7cd30d8947ff24cb46f8370 521 SUPERFAMILY SSF52317 3 233 5.32E-57 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Tharo_1739 66291e3bc7cd30d8947ff24cb46f8370 521 Gene3D G3DSA:3.30.300.10 402 521 1.4E-52 T 14-10-2018 Tharo_1739 66291e3bc7cd30d8947ff24cb46f8370 521 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 3 521 55.897 T 14-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 Tharo_1739 66291e3bc7cd30d8947ff24cb46f8370 521 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 209 521 2.3E-148 T 14-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 Tharo_1739 66291e3bc7cd30d8947ff24cb46f8370 521 Gene3D G3DSA:3.40.50.620 205 401 6.5E-74 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_1739 66291e3bc7cd30d8947ff24cb46f8370 521 Pfam PF00958 GMP synthase C terminal domain 429 520 4.9E-44 T 14-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 Tharo_1739 66291e3bc7cd30d8947ff24cb46f8370 521 SUPERFAMILY SSF52402 193 416 7.28E-59 T 14-10-2018 Tharo_1739 66291e3bc7cd30d8947ff24cb46f8370 521 Pfam PF00117 Glutamine amidotransferase class-I 8 195 1.9E-38 T 14-10-2018 IPR017926 Glutamine amidotransferase Tharo_1739 66291e3bc7cd30d8947ff24cb46f8370 521 SUPERFAMILY SSF54810 401 521 4.05E-51 T 14-10-2018 Tharo_1739 66291e3bc7cd30d8947ff24cb46f8370 521 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 6 200 1.1E-73 T 14-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 Tharo_1739 66291e3bc7cd30d8947ff24cb46f8370 521 PRINTS PR00097 Anthranilate synthase component II signature 173 186 3.9E-6 T 14-10-2018 Tharo_1739 66291e3bc7cd30d8947ff24cb46f8370 521 PRINTS PR00097 Anthranilate synthase component II signature 50 59 3.9E-6 T 14-10-2018 Tharo_1739 66291e3bc7cd30d8947ff24cb46f8370 521 PRINTS PR00097 Anthranilate synthase component II signature 77 88 3.9E-6 T 14-10-2018 Tharo_1739 66291e3bc7cd30d8947ff24cb46f8370 521 PRINTS PR00096 Glutamine amidotransferase superfamily signature 50 59 2.1E-7 T 14-10-2018 Tharo_1739 66291e3bc7cd30d8947ff24cb46f8370 521 PRINTS PR00096 Glutamine amidotransferase superfamily signature 173 186 2.1E-7 T 14-10-2018 Tharo_1739 66291e3bc7cd30d8947ff24cb46f8370 521 PRINTS PR00096 Glutamine amidotransferase superfamily signature 77 88 2.1E-7 T 14-10-2018 Tharo_1739 66291e3bc7cd30d8947ff24cb46f8370 521 Gene3D G3DSA:3.40.50.880 5 202 4.6E-54 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Tharo_2518 a3e2b7f96c5f0f335a172a93f47946df 146 SUPERFAMILY SSF102400 4 139 2.48E-33 T 14-10-2018 IPR036768 DNA polymerase III subunit chi superfamily Tharo_2518 a3e2b7f96c5f0f335a172a93f47946df 146 Pfam PF04364 DNA polymerase III chi subunit, HolC 4 135 6.1E-32 T 14-10-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 Tharo_2518 a3e2b7f96c5f0f335a172a93f47946df 146 Gene3D G3DSA:3.40.50.10110 3 139 1.4E-30 T 14-10-2018 IPR036768 DNA polymerase III subunit chi superfamily Tharo_2748 4522bcea95ea5b0581bd3bfe8c107a14 456 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 338 421 6.9E-6 T 14-10-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain Tharo_2748 4522bcea95ea5b0581bd3bfe8c107a14 456 Pfam PF13432 Tetratricopeptide repeat 50 113 1.4E-5 T 14-10-2018 Tharo_2748 4522bcea95ea5b0581bd3bfe8c107a14 456 Pfam PF13181 Tetratricopeptide repeat 116 147 0.0064 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Tharo_2748 4522bcea95ea5b0581bd3bfe8c107a14 456 Gene3D G3DSA:1.25.40.10 28 198 2.7E-25 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_2748 4522bcea95ea5b0581bd3bfe8c107a14 456 SMART SM00028 114 147 0.039 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Tharo_2748 4522bcea95ea5b0581bd3bfe8c107a14 456 SMART SM00028 46 79 0.57 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Tharo_2748 4522bcea95ea5b0581bd3bfe8c107a14 456 SMART SM00028 80 113 0.39 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Tharo_2748 4522bcea95ea5b0581bd3bfe8c107a14 456 SUPERFAMILY SSF48452 44 166 3.8E-24 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_2276 e904cbae6036379d7c79ba0a3c9f77fd 499 SMART SM00091 149 217 0.0054 T 14-10-2018 IPR000014 PAS domain Tharo_2276 e904cbae6036379d7c79ba0a3c9f77fd 499 SUPERFAMILY SSF55874 359 491 7.99E-20 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2276 e904cbae6036379d7c79ba0a3c9f77fd 499 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 402 492 1.6E-8 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2276 e904cbae6036379d7c79ba0a3c9f77fd 499 SMART SM00387 396 494 2.1E-7 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2276 e904cbae6036379d7c79ba0a3c9f77fd 499 Pfam PF08447 PAS fold 172 258 6.6E-15 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 Tharo_2276 e904cbae6036379d7c79ba0a3c9f77fd 499 Gene3D G3DSA:3.30.565.10 365 493 1.7E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2276 e904cbae6036379d7c79ba0a3c9f77fd 499 SMART SM00086 223 265 2.7E-5 T 14-10-2018 IPR001610 PAC motif Tharo_2276 e904cbae6036379d7c79ba0a3c9f77fd 499 Gene3D G3DSA:3.40.50.2300 11 143 1.3E-19 T 14-10-2018 Tharo_2276 e904cbae6036379d7c79ba0a3c9f77fd 499 SUPERFAMILY SSF52172 14 145 4.98E-24 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_2276 e904cbae6036379d7c79ba0a3c9f77fd 499 Pfam PF07730 Histidine kinase 293 358 2.2E-14 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Tharo_2276 e904cbae6036379d7c79ba0a3c9f77fd 499 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 146 272 3.0E-6 T 14-10-2018 IPR000014 PAS domain Tharo_2276 e904cbae6036379d7c79ba0a3c9f77fd 499 SUPERFAMILY SSF55785 136 263 1.66E-18 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_2276 e904cbae6036379d7c79ba0a3c9f77fd 499 SMART SM00448 12 124 7.2E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2276 e904cbae6036379d7c79ba0a3c9f77fd 499 Pfam PF00072 Response regulator receiver domain 15 116 1.1E-12 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2276 e904cbae6036379d7c79ba0a3c9f77fd 499 Gene3D G3DSA:2.10.70.100 220 266 7.0E-12 T 14-10-2018 Tharo_2276 e904cbae6036379d7c79ba0a3c9f77fd 499 Gene3D G3DSA:3.30.450.20 145 215 6.6E-16 T 14-10-2018 Tharo_0962 825f8af2cbcbc413ff92ed73212508ff 455 SUPERFAMILY SSF56954 14 441 3.66E-84 T 14-10-2018 Tharo_0962 825f8af2cbcbc413ff92ed73212508ff 455 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 34 454 1.5E-93 T 14-10-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0015562|GO:0019867|GO:0055085 Tharo_0962 825f8af2cbcbc413ff92ed73212508ff 455 Gene3D G3DSA:1.20.1600.10 35 455 2.4E-100 T 14-10-2018 Tharo_0962 825f8af2cbcbc413ff92ed73212508ff 455 Pfam PF02321 Outer membrane efflux protein 37 228 3.0E-25 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Tharo_0962 825f8af2cbcbc413ff92ed73212508ff 455 Pfam PF02321 Outer membrane efflux protein 255 439 8.5E-32 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Tharo_1042 cadd9932c7493f4de06b2be34dbe9dc7 369 SUPERFAMILY SSF51395 1 364 4.23E-113 T 14-10-2018 Tharo_1042 cadd9932c7493f4de06b2be34dbe9dc7 369 Gene3D G3DSA:3.20.20.70 1 369 5.7E-131 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_1042 cadd9932c7493f4de06b2be34dbe9dc7 369 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 3 340 5.5E-75 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 Tharo_0856 fc0b16b869a5f2629efc908ef900be82 501 Gene3D G3DSA:1.20.1250.20 55 470 4.6E-67 T 14-10-2018 Tharo_0856 fc0b16b869a5f2629efc908ef900be82 501 Pfam PF07690 Major Facilitator Superfamily 65 330 1.2E-28 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_0856 fc0b16b869a5f2629efc908ef900be82 501 SUPERFAMILY SSF103473 46 472 1.22E-73 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_0856 fc0b16b869a5f2629efc908ef900be82 501 ProSitePatterns PS00216 Sugar transport proteins signature 1. 114 130 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Tharo_2423 1aa192b9bcd90022e096bc58f2dc69b9 474 Gene3D G3DSA:1.10.287.470 120 166 3.2E-43 T 14-10-2018 Tharo_2423 1aa192b9bcd90022e096bc58f2dc69b9 474 Gene3D G3DSA:2.40.30.170 207 281 3.2E-43 T 14-10-2018 Tharo_2423 1aa192b9bcd90022e096bc58f2dc69b9 474 Gene3D G3DSA:2.40.50.100 85 206 3.2E-43 T 14-10-2018 Tharo_2423 1aa192b9bcd90022e096bc58f2dc69b9 474 Pfam PF11604 Copper binding periplasmic protein CusF 385 452 6.8E-23 T 14-10-2018 IPR021647 Copper binding periplasmic protein CusF Tharo_2423 1aa192b9bcd90022e096bc58f2dc69b9 474 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 58 354 7.9E-44 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Tharo_2423 1aa192b9bcd90022e096bc58f2dc69b9 474 Gene3D G3DSA:2.40.420.20 285 376 9.5E-24 T 14-10-2018 Tharo_2423 1aa192b9bcd90022e096bc58f2dc69b9 474 Pfam PF00529 HlyD membrane-fusion protein of T1SS 280 346 4.1E-7 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Tharo_2423 1aa192b9bcd90022e096bc58f2dc69b9 474 Gene3D G3DSA:2.40.50.320 378 460 6.6E-19 T 14-10-2018 Tharo_2423 1aa192b9bcd90022e096bc58f2dc69b9 474 SUPERFAMILY SSF111369 83 286 1.26E-17 T 14-10-2018 Tharo_2423 1aa192b9bcd90022e096bc58f2dc69b9 474 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 68 279 7.2E-72 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Tharo_0848 ffa10247e60db12bfe22b89607a16fa3 224 Gene3D G3DSA:3.40.50.720 1 224 1.3E-50 T 14-10-2018 Tharo_0848 ffa10247e60db12bfe22b89607a16fa3 224 Pfam PF00106 short chain dehydrogenase 3 185 2.2E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0848 ffa10247e60db12bfe22b89607a16fa3 224 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 1.5E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0848 ffa10247e60db12bfe22b89607a16fa3 224 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 1.5E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0848 ffa10247e60db12bfe22b89607a16fa3 224 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.5E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0848 ffa10247e60db12bfe22b89607a16fa3 224 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 1.5E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0848 ffa10247e60db12bfe22b89607a16fa3 224 SUPERFAMILY SSF51735 3 224 2.91E-54 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1750 f2612332784f222bb6f228aa44d19c25 167 Gene3D G3DSA:1.10.10.10 22 73 6.8E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1750 f2612332784f222bb6f228aa44d19c25 167 Pfam PF13404 AsnC-type helix-turn-helix domain 22 64 9.2E-9 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Tharo_1750 f2612332784f222bb6f228aa44d19c25 167 Gene3D G3DSA:3.30.70.3460 86 165 7.6E-16 T 14-10-2018 Tharo_0851 1f764ff1c93e5c086620567ea3a7cd38 168 Pfam PF01575 MaoC like domain 34 129 1.4E-14 T 14-10-2018 IPR002539 MaoC-like dehydratase domain Tharo_0851 1f764ff1c93e5c086620567ea3a7cd38 168 SUPERFAMILY SSF54637 19 163 6.77E-35 T 14-10-2018 IPR029069 HotDog domain superfamily Tharo_0851 1f764ff1c93e5c086620567ea3a7cd38 168 Gene3D G3DSA:3.10.129.10 14 164 4.7E-43 T 14-10-2018 Tharo_0064 42054517d136df99e7ac3e466f58734e 493 Gene3D G3DSA:2.30.42.10 407 490 6.1E-16 T 14-10-2018 Tharo_0064 42054517d136df99e7ac3e466f58734e 493 Gene3D G3DSA:2.30.42.10 286 392 9.8E-30 T 14-10-2018 Tharo_0064 42054517d136df99e7ac3e466f58734e 493 SUPERFAMILY SSF50156 407 492 6.97E-15 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 Tharo_0064 42054517d136df99e7ac3e466f58734e 493 SUPERFAMILY SSF50494 45 282 2.49E-65 T 14-10-2018 IPR009003 Peptidase S1, PA clan Tharo_0064 42054517d136df99e7ac3e466f58734e 493 Pfam PF13365 Trypsin-like peptidase domain 113 252 8.0E-35 T 14-10-2018 Tharo_0064 42054517d136df99e7ac3e466f58734e 493 Pfam PF13180 PDZ domain 292 378 2.8E-17 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Tharo_0064 42054517d136df99e7ac3e466f58734e 493 Gene3D G3DSA:2.40.10.120 46 285 3.2E-80 T 14-10-2018 Tharo_0064 42054517d136df99e7ac3e466f58734e 493 SUPERFAMILY SSF50156 249 373 1.71E-27 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 Tharo_0064 42054517d136df99e7ac3e466f58734e 493 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 48 488 2.3E-146 T 14-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 Tharo_0064 42054517d136df99e7ac3e466f58734e 493 PRINTS PR00834 HtrA/DegQ protease family signature 122 134 3.6E-50 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Tharo_0064 42054517d136df99e7ac3e466f58734e 493 PRINTS PR00834 HtrA/DegQ protease family signature 331 343 3.6E-50 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Tharo_0064 42054517d136df99e7ac3e466f58734e 493 PRINTS PR00834 HtrA/DegQ protease family signature 149 169 3.6E-50 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Tharo_0064 42054517d136df99e7ac3e466f58734e 493 PRINTS PR00834 HtrA/DegQ protease family signature 223 240 3.6E-50 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Tharo_0064 42054517d136df99e7ac3e466f58734e 493 PRINTS PR00834 HtrA/DegQ protease family signature 189 213 3.6E-50 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Tharo_0064 42054517d136df99e7ac3e466f58734e 493 PRINTS PR00834 HtrA/DegQ protease family signature 245 262 3.6E-50 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Tharo_0064 42054517d136df99e7ac3e466f58734e 493 SMART SM00228 407 483 4.6E-9 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Tharo_0064 42054517d136df99e7ac3e466f58734e 493 SMART SM00228 291 373 6.5E-16 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Tharo_1393 ab599d4c051091e7816c13186988260c 470 Gene3D G3DSA:3.40.50.620 8 325 9.9E-138 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_1393 ab599d4c051091e7816c13186988260c 470 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 16 27 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_1393 ab599d4c051091e7816c13186988260c 470 PRINTS PR00987 Glutamyl-tRNA synthetase signature 190 200 5.3E-27 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Tharo_1393 ab599d4c051091e7816c13186988260c 470 PRINTS PR00987 Glutamyl-tRNA synthetase signature 27 38 5.3E-27 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Tharo_1393 ab599d4c051091e7816c13186988260c 470 PRINTS PR00987 Glutamyl-tRNA synthetase signature 42 55 5.3E-27 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Tharo_1393 ab599d4c051091e7816c13186988260c 470 PRINTS PR00987 Glutamyl-tRNA synthetase signature 206 214 5.3E-27 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Tharo_1393 ab599d4c051091e7816c13186988260c 470 PRINTS PR00987 Glutamyl-tRNA synthetase signature 13 25 5.3E-27 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Tharo_1393 ab599d4c051091e7816c13186988260c 470 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 9 470 31.686 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Tharo_1393 ab599d4c051091e7816c13186988260c 470 SUPERFAMILY SSF52374 9 308 9.38E-111 T 14-10-2018 Tharo_1393 ab599d4c051091e7816c13186988260c 470 SUPERFAMILY SSF48163 310 469 1.83E-36 T 14-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Tharo_1393 ab599d4c051091e7816c13186988260c 470 Gene3D G3DSA:1.10.10.350 374 470 3.8E-18 T 14-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Tharo_1393 ab599d4c051091e7816c13186988260c 470 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 10 316 1.9E-105 T 14-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 Tharo_1393 ab599d4c051091e7816c13186988260c 470 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 10 468 6.5E-168 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Tharo_1674 76a6973f557a9db4ab86f7722c52ce6a 191 Gene3D G3DSA:3.30.1380.10 75 190 8.3E-12 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 Tharo_1674 76a6973f557a9db4ab86f7722c52ce6a 191 SUPERFAMILY SSF55166 72 189 2.16E-32 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 Tharo_1674 76a6973f557a9db4ab86f7722c52ce6a 191 Pfam PF05951 Bacterial protein of unknown function (DUF882) 41 186 1.7E-51 T 14-10-2018 IPR010275 Protein of unknown function DUF882 Tharo_2782 e11682f8d4d84c4da94e1e8cffc74158 194 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 2 182 1.1E-73 T 14-10-2018 IPR004507 Flavin prenyltransferase UbiX-like Tharo_2782 e11682f8d4d84c4da94e1e8cffc74158 194 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 184 36.03 T 14-10-2018 IPR004507 Flavin prenyltransferase UbiX-like Tharo_2782 e11682f8d4d84c4da94e1e8cffc74158 194 Gene3D G3DSA:3.40.50.1950 1 193 1.8E-76 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 Tharo_2782 e11682f8d4d84c4da94e1e8cffc74158 194 SUPERFAMILY SSF52507 1 184 7.06E-59 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 Tharo_2782 e11682f8d4d84c4da94e1e8cffc74158 194 Pfam PF02441 Flavoprotein 1 163 1.0E-24 T 14-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 SMART SM00464 13 205 1.2E-71 T 14-10-2018 IPR003111 Lon, substrate-binding domain Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 SUPERFAMILY SSF88697 12 204 3.48E-51 T 14-10-2018 IPR015947 PUA-like superfamily Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 Gene3D G3DSA:3.30.230.10 587 774 3.3E-78 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 572 774 3.9E-94 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 PIRSF PIRSF001174 3 777 0.0 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 Hamap MF_01973 Lon protease [lon]. 14 774 70.771 T 14-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 SMART SM00382 350 494 6.4E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 13 203 2.9E-44 T 14-10-2018 IPR003111 Lon, substrate-binding domain Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 705 724 2.2E-52 T 14-10-2018 Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 597 613 2.2E-52 T 14-10-2018 Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 728 746 2.2E-52 T 14-10-2018 Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 358 377 2.2E-52 T 14-10-2018 Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 675 694 2.2E-52 T 14-10-2018 Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 354 491 8.1E-17 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 TIGRFAM TIGR00763 lon: endopeptidase La 15 773 2.9E-294 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 678 686 - T 14-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 Gene3D G3DSA:2.30.130.40 5 120 2.0E-35 T 14-10-2018 Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 SUPERFAMILY SSF52540 317 588 6.44E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 Gene3D G3DSA:1.20.58.1480 124 248 5.0E-43 T 14-10-2018 Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 SUPERFAMILY SSF54211 597 772 3.72E-57 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 Gene3D G3DSA:3.40.50.300 316 492 3.5E-62 T 14-10-2018 Tharo_2660 b2a840354ed51ef66a8f9fdc44e7784b 808 Gene3D G3DSA:1.10.8.60 493 586 1.9E-33 T 14-10-2018 Tharo_3273 b56b8a56287136c1e66d2089b8c98235 616 ProSitePatterns PS00194 Thioredoxin family active site. 524 542 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 Tharo_3273 b56b8a56287136c1e66d2089b8c98235 616 Pfam PF11412 Disulphide bond corrector protein DsbC 27 141 8.6E-27 T 14-10-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain Tharo_3273 b56b8a56287136c1e66d2089b8c98235 616 SUPERFAMILY SSF74863 26 142 3.27E-29 T 14-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily Tharo_3273 b56b8a56287136c1e66d2089b8c98235 616 Pfam PF13899 Thioredoxin-like 511 589 9.1E-12 T 14-10-2018 Tharo_3273 b56b8a56287136c1e66d2089b8c98235 616 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 211 417 1.8E-15 T 14-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 Tharo_3273 b56b8a56287136c1e66d2089b8c98235 616 SUPERFAMILY SSF52833 501 613 7.68E-23 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_3273 b56b8a56287136c1e66d2089b8c98235 616 Gene3D G3DSA:2.60.40.1250 16 154 4.7E-32 T 14-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily Tharo_3273 b56b8a56287136c1e66d2089b8c98235 616 Hamap MF_00399 Thiol:disulfide interchange protein DsbD [dsbD]. 6 616 34.711 T 14-10-2018 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 Tharo_3273 b56b8a56287136c1e66d2089b8c98235 616 Gene3D G3DSA:3.40.30.10 494 615 2.0E-30 T 14-10-2018 Tharo_1196 6ec02987910e8e249883cc616ba2b3e9 397 SUPERFAMILY SSF53383 28 396 5.98E-120 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_1196 6ec02987910e8e249883cc616ba2b3e9 397 PIRSF PIRSF001434 1 397 8.5E-131 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Tharo_1196 6ec02987910e8e249883cc616ba2b3e9 397 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 15 395 1.3E-138 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Tharo_1196 6ec02987910e8e249883cc616ba2b3e9 397 Gene3D G3DSA:3.40.640.10 10 261 3.1E-88 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_1196 6ec02987910e8e249883cc616ba2b3e9 397 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 206 220 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Tharo_1196 6ec02987910e8e249883cc616ba2b3e9 397 Hamap MF_02056 O-succinylhomoserine sulfhydrylase [metZ]. 16 396 54.715 T 14-10-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 Tharo_1196 6ec02987910e8e249883cc616ba2b3e9 397 Gene3D G3DSA:3.90.1150.10 265 397 3.3E-48 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_1196 6ec02987910e8e249883cc616ba2b3e9 397 TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase 15 395 4.6E-176 T 14-10-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 Tharo_0130 f5186b0f84ce40d45d0eb550f7f12844 193 Pfam PF12802 MarR family 14 61 2.7E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_0130 f5186b0f84ce40d45d0eb550f7f12844 193 Gene3D G3DSA:3.30.460.10 94 177 9.9E-14 T 14-10-2018 Tharo_0130 f5186b0f84ce40d45d0eb550f7f12844 193 Pfam PF01909 Nucleotidyltransferase domain 106 135 1.3E-6 T 14-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Tharo_0130 f5186b0f84ce40d45d0eb550f7f12844 193 SUPERFAMILY SSF81301 101 184 1.17E-15 T 14-10-2018 Tharo_0130 f5186b0f84ce40d45d0eb550f7f12844 193 Gene3D G3DSA:1.10.10.10 1 93 2.0E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0130 f5186b0f84ce40d45d0eb550f7f12844 193 SUPERFAMILY SSF46785 3 87 1.79E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_2836 d718e279979bc2df7abdfec100b51df0 159 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Tharo_2836 d718e279979bc2df7abdfec100b51df0 159 TIGRFAM TIGR00754 bfr: bacterioferritin 1 155 3.0E-74 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Tharo_2836 d718e279979bc2df7abdfec100b51df0 159 Pfam PF00210 Ferritin-like domain 8 142 9.9E-37 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 Tharo_2836 d718e279979bc2df7abdfec100b51df0 159 PIRSF PIRSF002560 1 157 1.2E-72 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Tharo_2836 d718e279979bc2df7abdfec100b51df0 159 PRINTS PR00601 Bacterioferritin signature 23 43 3.2E-67 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Tharo_2836 d718e279979bc2df7abdfec100b51df0 159 PRINTS PR00601 Bacterioferritin signature 107 127 3.2E-67 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Tharo_2836 d718e279979bc2df7abdfec100b51df0 159 PRINTS PR00601 Bacterioferritin signature 128 149 3.2E-67 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Tharo_2836 d718e279979bc2df7abdfec100b51df0 159 PRINTS PR00601 Bacterioferritin signature 44 64 3.2E-67 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Tharo_2836 d718e279979bc2df7abdfec100b51df0 159 PRINTS PR00601 Bacterioferritin signature 3 22 3.2E-67 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Tharo_2836 d718e279979bc2df7abdfec100b51df0 159 PRINTS PR00601 Bacterioferritin signature 65 85 3.2E-67 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Tharo_2836 d718e279979bc2df7abdfec100b51df0 159 PRINTS PR00601 Bacterioferritin signature 86 106 3.2E-67 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Tharo_2836 d718e279979bc2df7abdfec100b51df0 159 SUPERFAMILY SSF47240 1 155 9.38E-55 T 14-10-2018 IPR009078 Ferritin-like superfamily Tharo_2836 d718e279979bc2df7abdfec100b51df0 159 Gene3D G3DSA:1.20.1260.10 1 157 8.9E-69 T 14-10-2018 IPR012347 Ferritin-like Tharo_2846 4a313fa20c264dbbe7b7b7a107c9c2fe 168 SUPERFAMILY SSF88946 9 75 2.31E-14 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Tharo_2846 4a313fa20c264dbbe7b7b7a107c9c2fe 168 Gene3D G3DSA:1.10.10.10 91 165 2.2E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2846 4a313fa20c264dbbe7b7b7a107c9c2fe 168 Pfam PF04542 Sigma-70 region 2 13 78 1.6E-15 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Tharo_2846 4a313fa20c264dbbe7b7b7a107c9c2fe 168 Pfam PF08281 Sigma-70, region 4 109 161 1.1E-12 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Tharo_2846 4a313fa20c264dbbe7b7b7a107c9c2fe 168 Gene3D G3DSA:1.10.1740.10 6 75 4.1E-10 T 14-10-2018 Tharo_2846 4a313fa20c264dbbe7b7b7a107c9c2fe 168 SUPERFAMILY SSF88659 102 163 4.49E-12 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Tharo_2846 4a313fa20c264dbbe7b7b7a107c9c2fe 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 160 1.2E-19 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Tharo_2408 62ea6c45a845f034066e6e476de48ebd 493 Gene3D G3DSA:3.40.50.300 1 237 4.9E-75 T 14-10-2018 Tharo_2408 62ea6c45a845f034066e6e476de48ebd 493 Gene3D G3DSA:3.40.50.300 243 492 2.8E-103 T 14-10-2018 Tharo_2408 62ea6c45a845f034066e6e476de48ebd 493 TIGRFAM TIGR03708 poly_P_AMP_trns: polyphosphate:AMP phosphotransferase 2 492 3.6E-216 T 14-10-2018 IPR022489 Polyphosphate:AMP phosphotransferase GO:0006797|GO:0043751 Tharo_2408 62ea6c45a845f034066e6e476de48ebd 493 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 13 232 2.8E-49 T 14-10-2018 IPR022488 Polyphosphate kinase-2-related Tharo_2408 62ea6c45a845f034066e6e476de48ebd 493 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 269 490 8.1E-90 T 14-10-2018 IPR022488 Polyphosphate kinase-2-related Tharo_2408 62ea6c45a845f034066e6e476de48ebd 493 SUPERFAMILY SSF52540 43 220 1.54E-13 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2408 62ea6c45a845f034066e6e476de48ebd 493 SUPERFAMILY SSF52540 300 485 6.97E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1947 7e9e1496c8c33d4533587f803c594361 589 Gene3D G3DSA:3.30.450.20 24 114 1.9E-8 T 14-10-2018 Tharo_1947 7e9e1496c8c33d4533587f803c594361 589 SUPERFAMILY SSF55073 139 297 2.43E-38 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_1947 7e9e1496c8c33d4533587f803c594361 589 SMART SM00267 124 296 6.2E-42 T 14-10-2018 IPR000160 GGDEF domain Tharo_1947 7e9e1496c8c33d4533587f803c594361 589 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 136 295 1.1E-26 T 14-10-2018 IPR000160 GGDEF domain Tharo_1947 7e9e1496c8c33d4533587f803c594361 589 Gene3D G3DSA:3.30.70.270 136 307 2.9E-44 T 14-10-2018 Tharo_1947 7e9e1496c8c33d4533587f803c594361 589 Pfam PF00563 EAL domain 313 549 4.4E-76 T 14-10-2018 IPR001633 EAL domain Tharo_1947 7e9e1496c8c33d4533587f803c594361 589 SMART SM00052 306 554 3.4E-116 T 14-10-2018 IPR001633 EAL domain Tharo_1947 7e9e1496c8c33d4533587f803c594361 589 Pfam PF00990 Diguanylate cyclase, GGDEF domain 135 290 6.9E-37 T 14-10-2018 IPR000160 GGDEF domain Tharo_1947 7e9e1496c8c33d4533587f803c594361 589 Gene3D G3DSA:3.20.20.450 308 563 2.0E-104 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_1947 7e9e1496c8c33d4533587f803c594361 589 SUPERFAMILY SSF55785 25 106 6.02E-9 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_1947 7e9e1496c8c33d4533587f803c594361 589 SUPERFAMILY SSF141868 313 560 3.53E-89 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_1957 b9b4ec87235cfd8c35bc40213815e66d 738 Gene3D G3DSA:3.30.70.260 662 738 7.4E-17 T 14-10-2018 Tharo_1957 b9b4ec87235cfd8c35bc40213815e66d 738 SUPERFAMILY SSF55021 661 737 1.83E-11 T 14-10-2018 Tharo_1957 b9b4ec87235cfd8c35bc40213815e66d 738 Gene3D G3DSA:1.10.3210.10 12 213 2.6E-43 T 14-10-2018 Tharo_1957 b9b4ec87235cfd8c35bc40213815e66d 738 SUPERFAMILY SSF109604 19 212 9.73E-44 T 14-10-2018 Tharo_1957 b9b4ec87235cfd8c35bc40213815e66d 738 Pfam PF13328 HD domain 35 198 9.2E-48 T 14-10-2018 IPR003607 HD/PDEase domain Tharo_1957 b9b4ec87235cfd8c35bc40213815e66d 738 SUPERFAMILY SSF81301 214 386 9.81E-60 T 14-10-2018 Tharo_1957 b9b4ec87235cfd8c35bc40213815e66d 738 Pfam PF13291 ACT domain 663 737 1.5E-17 T 14-10-2018 IPR002912 ACT domain Tharo_1957 b9b4ec87235cfd8c35bc40213815e66d 738 SMART SM00954 257 367 6.2E-64 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 Tharo_1957 b9b4ec87235cfd8c35bc40213815e66d 738 Pfam PF04607 Region found in RelA / SpoT proteins 257 366 7.6E-37 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 Tharo_1957 b9b4ec87235cfd8c35bc40213815e66d 738 Gene3D G3DSA:3.30.460.10 215 347 3.0E-49 T 14-10-2018 Tharo_1957 b9b4ec87235cfd8c35bc40213815e66d 738 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 41 736 1.6E-173 T 14-10-2018 IPR004811 RelA/SpoT family GO:0015969 Tharo_1957 b9b4ec87235cfd8c35bc40213815e66d 738 Gene3D G3DSA:3.10.20.30 404 473 3.3E-28 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Tharo_1957 b9b4ec87235cfd8c35bc40213815e66d 738 SUPERFAMILY SSF81271 399 467 1.02E-19 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 Tharo_1957 b9b4ec87235cfd8c35bc40213815e66d 738 Pfam PF02824 TGS domain 410 467 4.9E-23 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 Tharo_2063 674b7d2bb889c47e0b39c2b9878fd2d1 261 SUPERFAMILY SSF64005 17 239 4.05E-83 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 Tharo_2063 674b7d2bb889c47e0b39c2b9878fd2d1 261 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 19 244 39.07 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 Tharo_2063 674b7d2bb889c47e0b39c2b9878fd2d1 261 Gene3D G3DSA:3.40.1180.10 8 246 2.2E-88 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 Tharo_2063 674b7d2bb889c47e0b39c2b9878fd2d1 261 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 19 243 1.8E-83 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 Tharo_2063 674b7d2bb889c47e0b39c2b9878fd2d1 261 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 189 206 - T 14-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 Tharo_2063 674b7d2bb889c47e0b39c2b9878fd2d1 261 Pfam PF01255 Putative undecaprenyl diphosphate synthase 26 243 1.1E-77 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 Tharo_0938 beda16fde09fd82385b59289368f4e7d 295 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 280 5.4E-40 T 14-10-2018 IPR016040 NAD(P)-binding domain Tharo_0938 beda16fde09fd82385b59289368f4e7d 295 Gene3D G3DSA:3.90.25.10 170 288 1.4E-89 T 14-10-2018 Tharo_0938 beda16fde09fd82385b59289368f4e7d 295 Gene3D G3DSA:3.40.50.720 4 281 1.4E-89 T 14-10-2018 Tharo_0938 beda16fde09fd82385b59289368f4e7d 295 SUPERFAMILY SSF51735 2 293 1.48E-63 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_3179 23f3caebaae1de4f1f5fdc0acec37998 496 Gene3D G3DSA:2.20.200.10 130 383 8.6E-141 T 14-10-2018 Tharo_3179 23f3caebaae1de4f1f5fdc0acec37998 496 Gene3D G3DSA:1.20.1600.10 84 495 8.6E-141 T 14-10-2018 Tharo_3179 23f3caebaae1de4f1f5fdc0acec37998 496 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 41 494 1.1E-124 T 14-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 Tharo_3179 23f3caebaae1de4f1f5fdc0acec37998 496 SUPERFAMILY SSF56954 31 496 1.83E-109 T 14-10-2018 Tharo_3179 23f3caebaae1de4f1f5fdc0acec37998 496 Pfam PF02321 Outer membrane efflux protein 309 492 1.8E-25 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Tharo_3179 23f3caebaae1de4f1f5fdc0acec37998 496 Pfam PF02321 Outer membrane efflux protein 93 283 3.6E-27 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Tharo_0337 ea7c8ec42ad45be4158c58a10fdfe188 367 Pfam PF02119 Flagellar P-ring protein 25 366 4.2E-135 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 Tharo_0337 ea7c8ec42ad45be4158c58a10fdfe188 367 Hamap MF_00416 Flagellar P-ring protein [flgI]. 4 367 36.643 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 Tharo_0337 ea7c8ec42ad45be4158c58a10fdfe188 367 PRINTS PR01010 Flagellar P-ring protein signature 85 104 2.4E-74 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 Tharo_0337 ea7c8ec42ad45be4158c58a10fdfe188 367 PRINTS PR01010 Flagellar P-ring protein signature 255 267 2.4E-74 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 Tharo_0337 ea7c8ec42ad45be4158c58a10fdfe188 367 PRINTS PR01010 Flagellar P-ring protein signature 191 209 2.4E-74 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 Tharo_0337 ea7c8ec42ad45be4158c58a10fdfe188 367 PRINTS PR01010 Flagellar P-ring protein signature 107 124 2.4E-74 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 Tharo_0337 ea7c8ec42ad45be4158c58a10fdfe188 367 PRINTS PR01010 Flagellar P-ring protein signature 124 142 2.4E-74 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 Tharo_0337 ea7c8ec42ad45be4158c58a10fdfe188 367 PRINTS PR01010 Flagellar P-ring protein signature 24 39 2.4E-74 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 Tharo_0337 ea7c8ec42ad45be4158c58a10fdfe188 367 PRINTS PR01010 Flagellar P-ring protein signature 39 54 2.4E-74 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 Tharo_0337 ea7c8ec42ad45be4158c58a10fdfe188 367 PRINTS PR01010 Flagellar P-ring protein signature 59 74 2.4E-74 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 Tharo_0053 b9cc3d806a2e85bcb69b5bd47cce5a9f 279 Hamap MF_00188 Protease HtpX [htpX]. 5 278 28.351 T 14-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 Tharo_0053 b9cc3d806a2e85bcb69b5bd47cce5a9f 279 Pfam PF01435 Peptidase family M48 68 278 4.4E-40 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 Tharo_0053 b9cc3d806a2e85bcb69b5bd47cce5a9f 279 Gene3D G3DSA:3.30.2010.10 60 150 2.6E-32 T 14-10-2018 Tharo_0184 126f81baa242684226ff15b67b74a386 708 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 58 116 1.0E-8 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Tharo_0184 126f81baa242684226ff15b67b74a386 708 Gene3D G3DSA:3.10.20.30 49 153 1.8E-16 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Tharo_0184 126f81baa242684226ff15b67b74a386 708 Gene3D G3DSA:3.30.420.480 274 456 5.7E-49 T 14-10-2018 Tharo_0184 126f81baa242684226ff15b67b74a386 708 SUPERFAMILY SSF54292 41 145 3.77E-16 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Tharo_0184 126f81baa242684226ff15b67b74a386 708 SUPERFAMILY SSF53067 278 602 1.78E-9 T 14-10-2018 Tharo_0184 126f81baa242684226ff15b67b74a386 708 Pfam PF14574 Domain of unknown function (DUF4445) 276 676 2.7E-126 T 14-10-2018 IPR027980 Protein of unknown function DUF4445 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 Gene3D G3DSA:1.10.730.10 9 806 0.0 T 14-10-2018 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 SUPERFAMILY SSF52374 4 674 7.74E-151 T 14-10-2018 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 SUPERFAMILY SSF47323 669 874 4.49E-29 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 5 874 0.0 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 SUPERFAMILY SSF50677 226 420 8.79E-49 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 408 1.1E-67 T 14-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 625 665 6.5E-7 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 422 598 8.0E-8 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 875 22.923 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 Gene3D G3DSA:3.90.740.10 227 419 0.0 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 Pfam PF09334 tRNA synthetases class I (M) 39 171 1.2E-17 T 14-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 Pfam PF08264 Anticodon-binding domain of tRNA 714 837 3.7E-18 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 PRINTS PR00985 Leucyl-tRNA synthetase signature 530 552 4.3E-49 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 4.3E-49 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 PRINTS PR00985 Leucyl-tRNA synthetase signature 492 510 4.3E-49 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 4.3E-49 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 PRINTS PR00985 Leucyl-tRNA synthetase signature 185 198 4.3E-49 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 PRINTS PR00985 Leucyl-tRNA synthetase signature 563 573 4.3E-49 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 4.3E-49 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 Gene3D G3DSA:3.10.330.110 573 635 0.0 T 14-10-2018 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 Gene3D G3DSA:3.10.20.590 814 875 1.7E-20 T 14-10-2018 Tharo_2472 f4718316296a47cdb235d0916cf68c84 875 Gene3D G3DSA:3.40.50.620 33 572 0.0 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_3227 ed7e496c0b8245fd5010c17211b6e889 104 Gene3D G3DSA:3.30.2310.20 1 97 2.8E-15 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_3227 ed7e496c0b8245fd5010c17211b6e889 104 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 92 4.3E-9 T 14-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Tharo_2376 752f129d11a35dc0165ada758888cd50 454 Pfam PF01523 Putative modulator of DNA gyrase 33 331 1.1E-62 T 14-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 Tharo_2376 752f129d11a35dc0165ada758888cd50 454 SUPERFAMILY SSF111283 12 454 1.05E-124 T 14-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 Tharo_2376 752f129d11a35dc0165ada758888cd50 454 Gene3D G3DSA:3.30.2290.10 5 240 5.4E-85 T 14-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal Tharo_1559 e05639cabae62cc3a04947795f5a59f2 267 Gene3D G3DSA:3.40.50.10090 21 256 4.1E-78 T 14-10-2018 Tharo_1559 e05639cabae62cc3a04947795f5a59f2 267 Gene3D G3DSA:3.40.50.10090 50 184 4.1E-78 T 14-10-2018 Tharo_1559 e05639cabae62cc3a04947795f5a59f2 267 Pfam PF02602 Uroporphyrinogen-III synthase HemD 34 251 7.4E-45 T 14-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Tharo_1559 e05639cabae62cc3a04947795f5a59f2 267 SUPERFAMILY SSF69618 18 265 1.57E-56 T 14-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Tharo_1565 ab180e3342cf0adbb57fe9d6bf7cfc9f 531 SMART SM00798 135 463 1.2E-210 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Tharo_1565 ab180e3342cf0adbb57fe9d6bf7cfc9f 531 Pfam PF01808 AICARFT/IMPCHase bienzyme 135 461 1.7E-120 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Tharo_1565 ab180e3342cf0adbb57fe9d6bf7cfc9f 531 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 5 531 7.1E-223 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Tharo_1565 ab180e3342cf0adbb57fe9d6bf7cfc9f 531 PIRSF PIRSF000414 1 531 5.6E-218 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Tharo_1565 ab180e3342cf0adbb57fe9d6bf7cfc9f 531 Gene3D G3DSA:3.40.140.20 218 375 1.7E-59 T 14-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Tharo_1565 ab180e3342cf0adbb57fe9d6bf7cfc9f 531 SUPERFAMILY SSF53927 221 531 2.11E-130 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Tharo_1565 ab180e3342cf0adbb57fe9d6bf7cfc9f 531 SUPERFAMILY SSF52335 4 198 4.32E-70 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily Tharo_1565 ab180e3342cf0adbb57fe9d6bf7cfc9f 531 Pfam PF02142 MGS-like domain 15 130 3.1E-31 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain Tharo_1565 ab180e3342cf0adbb57fe9d6bf7cfc9f 531 Gene3D G3DSA:3.40.140.20 394 531 3.3E-59 T 14-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Tharo_1565 ab180e3342cf0adbb57fe9d6bf7cfc9f 531 Gene3D G3DSA:3.40.50.1380 1 203 7.0E-85 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily Tharo_1565 ab180e3342cf0adbb57fe9d6bf7cfc9f 531 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 3 531 44.93 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Tharo_1565 ab180e3342cf0adbb57fe9d6bf7cfc9f 531 SMART SM00851 15 130 4.8E-65 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain Tharo_3062 771395dc476f9a472be4f3307cca1d47 872 Pfam PF03176 MMPL family 586 791 1.8E-12 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 Tharo_3062 771395dc476f9a472be4f3307cca1d47 872 Pfam PF03176 MMPL family 180 424 8.1E-8 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 Tharo_3062 771395dc476f9a472be4f3307cca1d47 872 SUPERFAMILY SSF82866 597 793 1.83E-30 T 14-10-2018 Tharo_3062 771395dc476f9a472be4f3307cca1d47 872 SUPERFAMILY SSF82866 205 398 1.44E-26 T 14-10-2018 Tharo_3062 771395dc476f9a472be4f3307cca1d47 872 Gene3D G3DSA:1.20.1640.10 593 801 3.0E-10 T 14-10-2018 Tharo_0565 01f04a4646756303bbc10d386166983f 298 PIRSF PIRSF003097 3 297 2.7E-60 T 14-10-2018 IPR004513 Cell division protein FtsX GO:0016021 Tharo_0118 b0c379451cccd12555300e5dfa57f533 139 Gene3D G3DSA:1.20.5.440 90 132 2.1E-13 T 14-10-2018 Tharo_0118 b0c379451cccd12555300e5dfa57f533 139 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 8 89 1.0E-35 T 14-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0118 b0c379451cccd12555300e5dfa57f533 139 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 1 130 21.782 T 14-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0118 b0c379451cccd12555300e5dfa57f533 139 Gene3D G3DSA:2.60.15.10 1 89 5.2E-30 T 14-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0118 b0c379451cccd12555300e5dfa57f533 139 SUPERFAMILY SSF51344 1 85 3.92E-23 T 14-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0118 b0c379451cccd12555300e5dfa57f533 139 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 83 2.8E-28 T 14-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0118 b0c379451cccd12555300e5dfa57f533 139 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 2 132 7.8E-43 T 14-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0118 b0c379451cccd12555300e5dfa57f533 139 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 88 132 7.4E-9 T 14-10-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Tharo_0118 b0c379451cccd12555300e5dfa57f533 139 SUPERFAMILY SSF46604 87 136 2.33E-13 T 14-10-2018 IPR036794 ATP synthase delta/epsilon subunit, C-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0654 6f8fbd8f4e2375e34ebe39ac646157f4 255 Pfam PF12706 Beta-lactamase superfamily domain 28 237 3.7E-20 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_0654 6f8fbd8f4e2375e34ebe39ac646157f4 255 SMART SM00849 18 222 9.2E-10 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_0654 6f8fbd8f4e2375e34ebe39ac646157f4 255 SUPERFAMILY SSF56281 1 222 1.83E-44 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_0654 6f8fbd8f4e2375e34ebe39ac646157f4 255 PRINTS PR00388 3'5'-cyclic nucleotide class II phosphodiesterase signature 82 103 4.0E-7 T 14-10-2018 IPR000396 Cyclic-AMP phosphodiesterase, class-II GO:0004115|GO:0006198 Tharo_0654 6f8fbd8f4e2375e34ebe39ac646157f4 255 PRINTS PR00388 3'5'-cyclic nucleotide class II phosphodiesterase signature 196 209 4.0E-7 T 14-10-2018 IPR000396 Cyclic-AMP phosphodiesterase, class-II GO:0004115|GO:0006198 Tharo_0654 6f8fbd8f4e2375e34ebe39ac646157f4 255 PRINTS PR00388 3'5'-cyclic nucleotide class II phosphodiesterase signature 50 68 4.0E-7 T 14-10-2018 IPR000396 Cyclic-AMP phosphodiesterase, class-II GO:0004115|GO:0006198 Tharo_0654 6f8fbd8f4e2375e34ebe39ac646157f4 255 Gene3D G3DSA:3.60.15.10 1 239 3.1E-39 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_0993 2df930b9f87140eedecea69e484b9846 216 Gene3D G3DSA:1.25.40.10 42 212 2.7E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_0993 2df930b9f87140eedecea69e484b9846 216 Pfam PF09976 Tetratricopeptide repeat-like domain 17 215 2.8E-57 T 14-10-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 Tharo_0993 2df930b9f87140eedecea69e484b9846 216 PIRSF PIRSF006170 3 216 6.0E-50 T 14-10-2018 IPR026039 Uncharacterised protein family UPF0070 Tharo_2174 35b29774040ad91565d5f98d8460af3b 600 Gene3D G3DSA:1.10.390.60 189 463 5.5E-103 T 14-10-2018 Tharo_2174 35b29774040ad91565d5f98d8460af3b 600 Pfam PF05299 M61 glycyl aminopeptidase 282 398 2.0E-46 T 14-10-2018 IPR007963 Peptidase M61, catalytic domain Tharo_2174 35b29774040ad91565d5f98d8460af3b 600 Pfam PF13180 PDZ domain 491 569 4.7E-12 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Tharo_2174 35b29774040ad91565d5f98d8460af3b 600 Gene3D G3DSA:2.60.40.3650 7 186 8.9E-58 T 14-10-2018 Tharo_2174 35b29774040ad91565d5f98d8460af3b 600 Gene3D G3DSA:2.30.42.10 492 597 1.1E-19 T 14-10-2018 Tharo_2174 35b29774040ad91565d5f98d8460af3b 600 SMART SM00228 491 560 4.4E-7 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Tharo_2174 35b29774040ad91565d5f98d8460af3b 600 SUPERFAMILY SSF55486 210 460 4.39E-9 T 14-10-2018 Tharo_2174 35b29774040ad91565d5f98d8460af3b 600 SUPERFAMILY SSF50156 486 582 6.84E-12 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 Tharo_2174 35b29774040ad91565d5f98d8460af3b 600 PIRSF PIRSF016493 4 598 1.4E-213 T 14-10-2018 IPR024191 Peptidase M61 Tharo_2714 8f78efaf2cad1ef76820aadeb3511aa4 119 SUPERFAMILY SSF50193 1 118 1.83E-48 T 14-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 Tharo_2714 8f78efaf2cad1ef76820aadeb3511aa4 119 SMART SM01374 1 119 2.1E-78 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 Tharo_2714 8f78efaf2cad1ef76820aadeb3511aa4 119 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 119 4.7E-55 T 14-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 Tharo_2714 8f78efaf2cad1ef76820aadeb3511aa4 119 ProSitePatterns PS00049 Ribosomal protein L14 signature. 57 83 - T 14-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2714 8f78efaf2cad1ef76820aadeb3511aa4 119 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 119 24.453 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 Tharo_2714 8f78efaf2cad1ef76820aadeb3511aa4 119 Pfam PF00238 Ribosomal protein L14p/L23e 1 119 6.6E-52 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 Tharo_2714 8f78efaf2cad1ef76820aadeb3511aa4 119 Gene3D G3DSA:2.40.150.20 1 119 2.0E-51 T 14-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 Tharo_0111 9102981d37aca84197fe64150e865239 281 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 35 276 7.1E-40 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0111 9102981d37aca84197fe64150e865239 281 Hamap MF_01393 ATP synthase subunit a [atpB]. 9 281 13.725 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0111 9102981d37aca84197fe64150e865239 281 Pfam PF00119 ATP synthase A chain 40 274 5.6E-54 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0111 9102981d37aca84197fe64150e865239 281 Gene3D G3DSA:1.20.120.220 91 281 1.8E-51 T 14-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0111 9102981d37aca84197fe64150e865239 281 ProSitePatterns PS00449 ATP synthase a subunit signature. 210 219 - T 14-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0111 9102981d37aca84197fe64150e865239 281 SUPERFAMILY SSF81336 93 274 1.44E-38 T 14-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_2369 70da469f10fded68f34fbf00523c6588 359 Hamap MF_01113 DNA polymerase IV [dinB]. 5 353 36.574 T 14-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 Tharo_2369 70da469f10fded68f34fbf00523c6588 359 Gene3D G3DSA:1.10.150.20 174 233 3.6E-21 T 14-10-2018 Tharo_2369 70da469f10fded68f34fbf00523c6588 359 Pfam PF11798 IMS family HHH motif 170 201 8.4E-8 T 14-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 Tharo_2369 70da469f10fded68f34fbf00523c6588 359 SUPERFAMILY SSF56672 5 238 3.02E-94 T 14-10-2018 Tharo_2369 70da469f10fded68f34fbf00523c6588 359 Gene3D G3DSA:2.30.40.20 15 72 9.4E-28 T 14-10-2018 Tharo_2369 70da469f10fded68f34fbf00523c6588 359 Gene3D G3DSA:3.30.70.270 73 173 1.4E-37 T 14-10-2018 Tharo_2369 70da469f10fded68f34fbf00523c6588 359 SUPERFAMILY SSF100879 245 345 8.04E-20 T 14-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 Tharo_2369 70da469f10fded68f34fbf00523c6588 359 Pfam PF00817 impB/mucB/samB family 12 158 1.6E-52 T 14-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 Tharo_2369 70da469f10fded68f34fbf00523c6588 359 Pfam PF11799 impB/mucB/samB family C-terminal domain 238 338 5.5E-6 T 14-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 Tharo_2369 70da469f10fded68f34fbf00523c6588 359 Gene3D G3DSA:3.30.1490.100 241 352 4.3E-21 T 14-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 Tharo_2279 e4ae0e3724962c6ddca8887da7ac5ba4 283 PIRSF PIRSF006241 1 261 4.0E-92 T 14-10-2018 IPR026040 Hydroxypyruvate isomerase-like Tharo_2279 e4ae0e3724962c6ddca8887da7ac5ba4 283 TIGRFAM TIGR03234 OH-pyruv-isom: hydroxypyruvate isomerase 2 255 1.8E-118 T 14-10-2018 IPR017643 Hydroxypyruvate isomerase KEGG: 00630+5.3.1.22 Tharo_2279 e4ae0e3724962c6ddca8887da7ac5ba4 283 Pfam PF01261 Xylose isomerase-like TIM barrel 21 219 7.3E-33 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain Tharo_2279 e4ae0e3724962c6ddca8887da7ac5ba4 283 Gene3D G3DSA:3.20.20.150 1 261 3.4E-79 T 14-10-2018 Tharo_2279 e4ae0e3724962c6ddca8887da7ac5ba4 283 SUPERFAMILY SSF51658 1 256 4.98E-85 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily Tharo_0322 9f921ba745c9a1a24dd7779524765c90 441 Gene3D G3DSA:3.30.160.390 1 102 1.7E-30 T 14-10-2018 IPR038488 Integrase, DNA-binding domain superfamily Tharo_0322 9f921ba745c9a1a24dd7779524765c90 441 Pfam PF00589 Phage integrase family 217 389 1.1E-17 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Tharo_0322 9f921ba745c9a1a24dd7779524765c90 441 Pfam PF13356 Arm DNA-binding domain 2 86 1.5E-16 T 14-10-2018 IPR025166 Integrase, DNA-binding domain Tharo_0322 9f921ba745c9a1a24dd7779524765c90 441 Gene3D G3DSA:1.10.443.10 219 399 8.5E-16 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Tharo_0322 9f921ba745c9a1a24dd7779524765c90 441 Gene3D G3DSA:1.10.150.130 103 182 4.1E-19 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Tharo_0322 9f921ba745c9a1a24dd7779524765c90 441 SUPERFAMILY SSF56349 97 399 6.47E-48 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Tharo_0515 fda087254484a30dba1d4886c47295e6 315 Gene3D G3DSA:3.90.79.10 1 129 2.5E-36 T 14-10-2018 Tharo_0515 fda087254484a30dba1d4886c47295e6 315 Gene3D G3DSA:3.20.20.70 130 315 3.9E-48 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_0515 fda087254484a30dba1d4886c47295e6 315 Pfam PF00293 NUDIX domain 8 126 3.4E-19 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Tharo_0515 fda087254484a30dba1d4886c47295e6 315 Pfam PF02581 Thiamine monophosphate synthase 136 309 4.0E-40 T 14-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Tharo_0515 fda087254484a30dba1d4886c47295e6 315 SUPERFAMILY SSF55811 4 128 1.76E-34 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Tharo_0515 fda087254484a30dba1d4886c47295e6 315 ProSitePatterns PS00893 Nudix box signature. 40 61 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Tharo_0515 fda087254484a30dba1d4886c47295e6 315 SUPERFAMILY SSF51391 116 314 1.57E-49 T 14-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Tharo_0515 fda087254484a30dba1d4886c47295e6 315 PRINTS PR00502 NUDIX hydrolase family signature 35 49 3.7E-8 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Tharo_0515 fda087254484a30dba1d4886c47295e6 315 PRINTS PR00502 NUDIX hydrolase family signature 49 64 3.7E-8 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Tharo_2592 966353a01ab6ed881274d4081f29ff35 300 SUPERFAMILY SSF46785 12 88 8.16E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_2592 966353a01ab6ed881274d4081f29ff35 300 Gene3D G3DSA:1.10.10.10 14 101 9.5E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2592 966353a01ab6ed881274d4081f29ff35 300 SUPERFAMILY SSF53850 98 299 3.26E-33 T 14-10-2018 Tharo_2592 966353a01ab6ed881274d4081f29ff35 300 Gene3D G3DSA:3.40.190.10 107 294 7.6E-44 T 14-10-2018 Tharo_2592 966353a01ab6ed881274d4081f29ff35 300 Gene3D G3DSA:3.40.190.10 167 267 7.6E-44 T 14-10-2018 Tharo_2592 966353a01ab6ed881274d4081f29ff35 300 Pfam PF03466 LysR substrate binding domain 96 298 3.9E-30 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_2592 966353a01ab6ed881274d4081f29ff35 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 71 1.5E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1997 75c18ba07624d688b5d6cc090e5a3e90 453 SUPERFAMILY SSF103473 7 438 7.46E-84 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_1997 75c18ba07624d688b5d6cc090e5a3e90 453 ProSitePatterns PS00217 Sugar transport proteins signature 2. 118 143 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Tharo_1997 75c18ba07624d688b5d6cc090e5a3e90 453 Gene3D G3DSA:1.20.1250.20 13 443 1.1E-75 T 14-10-2018 Tharo_1997 75c18ba07624d688b5d6cc090e5a3e90 453 Pfam PF07690 Major Facilitator Superfamily 27 356 4.5E-38 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_2201 1e71de0548bb940e227337f98c0ca8e1 194 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 3 190 9.7E-83 T 14-10-2018 IPR011293 Ion-translocating oxidoreductase complex, subunit RnfA/RsxA GO:0022900 Tharo_2201 1e71de0548bb940e227337f98c0ca8e1 194 Hamap MF_00459 Ion-translocating oxidoreductase complex subunit A [rsxA]. 2 191 25.458 T 14-10-2018 IPR011293 Ion-translocating oxidoreductase complex, subunit RnfA/RsxA GO:0022900 Tharo_2201 1e71de0548bb940e227337f98c0ca8e1 194 PIRSF PIRSF006102 1 193 1.4E-57 T 14-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 Tharo_2201 1e71de0548bb940e227337f98c0ca8e1 194 Pfam PF02508 Rnf-Nqr subunit, membrane protein 7 190 6.3E-60 T 14-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 Tharo_0652 2973567ae79e695ff50a4cd5b604999b 297 PRINTS PR01798 Succinyl-CoA synthase signature 186 204 1.0E-31 T 14-10-2018 Tharo_0652 2973567ae79e695ff50a4cd5b604999b 297 PRINTS PR01798 Succinyl-CoA synthase signature 217 230 1.0E-31 T 14-10-2018 Tharo_0652 2973567ae79e695ff50a4cd5b604999b 297 PRINTS PR01798 Succinyl-CoA synthase signature 249 266 1.0E-31 T 14-10-2018 Tharo_0652 2973567ae79e695ff50a4cd5b604999b 297 PRINTS PR01798 Succinyl-CoA synthase signature 85 102 1.0E-31 T 14-10-2018 Tharo_0652 2973567ae79e695ff50a4cd5b604999b 297 SUPERFAMILY SSF52210 132 296 3.27E-53 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_0652 2973567ae79e695ff50a4cd5b604999b 297 Gene3D G3DSA:3.40.50.720 2 132 2.4E-41 T 14-10-2018 Tharo_0652 2973567ae79e695ff50a4cd5b604999b 297 Gene3D G3DSA:3.40.50.261 133 297 4.2E-66 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_0652 2973567ae79e695ff50a4cd5b604999b 297 SUPERFAMILY SSF51735 1 117 1.33E-34 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_0652 2973567ae79e695ff50a4cd5b604999b 297 PIRSF PIRSF001553 1 297 4.6E-112 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Tharo_0652 2973567ae79e695ff50a4cd5b604999b 297 Pfam PF00549 CoA-ligase 160 271 8.5E-15 T 14-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_0652 2973567ae79e695ff50a4cd5b604999b 297 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 161 190 - T 14-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site Tharo_0652 2973567ae79e695ff50a4cd5b604999b 297 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 297 2.3E-124 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Tharo_0652 2973567ae79e695ff50a4cd5b604999b 297 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 245 258 - T 14-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site Tharo_0652 2973567ae79e695ff50a4cd5b604999b 297 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 297 39.477 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Tharo_0652 2973567ae79e695ff50a4cd5b604999b 297 SMART SM00881 4 103 5.0E-29 T 14-10-2018 IPR003781 CoA-binding GO:0048037 Tharo_0652 2973567ae79e695ff50a4cd5b604999b 297 Pfam PF02629 CoA binding domain 6 102 3.3E-22 T 14-10-2018 IPR003781 CoA-binding GO:0048037 Tharo_2353 2bbfbdd16a102a56d425049258ab110f 162 Gene3D G3DSA:3.40.50.1240 8 155 1.7E-27 T 14-10-2018 IPR029033 Histidine phosphatase superfamily Tharo_2353 2bbfbdd16a102a56d425049258ab110f 162 PIRSF PIRSF000709 12 82 4.9E-4 T 14-10-2018 Tharo_2353 2bbfbdd16a102a56d425049258ab110f 162 SUPERFAMILY SSF53254 14 142 2.75E-19 T 14-10-2018 IPR029033 Histidine phosphatase superfamily Tharo_2353 2bbfbdd16a102a56d425049258ab110f 162 SMART SM00855 14 118 7.8E-8 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Tharo_2353 2bbfbdd16a102a56d425049258ab110f 162 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 15 78 2.0E-8 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 Gene3D G3DSA:3.20.20.450 1648 1906 1.8E-88 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 Pfam PF08447 PAS fold 718 803 1.1E-17 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 SUPERFAMILY SSF55874 902 1077 9.56E-45 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 SUPERFAMILY SSF47384 835 914 7.06E-22 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 Pfam PF00512 His Kinase A (phospho-acceptor) domain 848 913 1.3E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 Pfam PF00072 Response regulator receiver domain 1238 1350 3.4E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 Pfam PF00072 Response regulator receiver domain 1512 1628 4.8E-16 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 SUPERFAMILY SSF55785 698 813 9.87E-21 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 Gene3D G3DSA:3.30.565.10 912 1082 1.3E-44 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 Gene3D G3DSA:3.30.450.350 273 465 9.4E-15 T 14-10-2018 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 961 1078 4.4E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 Gene3D G3DSA:1.20.120.160 1381 1494 3.1E-17 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 Pfam PF01627 Hpt domain 1408 1491 2.3E-7 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 Gene3D G3DSA:1.10.287.130 810 911 1.7E-28 T 14-10-2018 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 690 817 2.8E-7 T 14-10-2018 IPR000014 PAS domain Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 542 669 9.2E-13 T 14-10-2018 IPR000014 PAS domain Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 Pfam PF00563 EAL domain 1650 1884 6.1E-67 T 14-10-2018 IPR001633 EAL domain Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 SMART SM00091 545 615 2.0E-4 T 14-10-2018 IPR000014 PAS domain Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 SMART SM00091 692 762 1.0E-5 T 14-10-2018 IPR000014 PAS domain Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 SUPERFAMILY SSF52172 1510 1641 2.13E-23 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1063 1076 2.4E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1039 1057 2.4E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1022 1032 2.4E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1004 1018 2.4E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 SMART SM00388 848 913 1.4E-22 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 SUPERFAMILY SSF141868 1650 1897 1.03E-80 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 Pfam PF08448 PAS fold 552 663 4.7E-13 T 14-10-2018 IPR013656 PAS fold-4 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 Pfam PF05231 MASE1 27 225 1.9E-8 T 14-10-2018 IPR007895 MASE1 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 SMART SM01079 269 467 8.4E-17 T 14-10-2018 IPR006189 CHASE domain Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 Gene3D G3DSA:3.40.50.2300 1230 1354 6.7E-37 T 14-10-2018 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 SMART SM00387 960 1079 2.7E-36 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 Gene3D G3DSA:3.30.450.20 551 677 7.0E-26 T 14-10-2018 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 Pfam PF03924 CHASE domain 272 453 2.8E-24 T 14-10-2018 IPR006189 CHASE domain Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 SUPERFAMILY SSF52172 1236 1356 3.7E-35 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 Gene3D G3DSA:3.30.450.20 690 807 5.0E-27 T 14-10-2018 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 Gene3D G3DSA:3.40.50.2300 1508 1639 1.3E-25 T 14-10-2018 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 SMART SM00448 1236 1350 9.6E-33 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 SMART SM00448 1510 1629 3.0E-14 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 SUPERFAMILY SSF55785 536 659 3.22E-17 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 SMART SM00052 1644 1889 9.0E-96 T 14-10-2018 IPR001633 EAL domain Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 SMART SM00086 768 810 2.1E-5 T 14-10-2018 IPR001610 PAC motif Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 SMART SM00086 620 662 0.03 T 14-10-2018 IPR001610 PAC motif Tharo_3051 bab37152eb500948ced6ea2db01cde81 1909 SUPERFAMILY SSF47226 1378 1495 2.49E-22 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 Tharo_3346 50a8fae40ec2eaeac95aa7613aec256e 403 Pfam PF12704 MacB-like periplasmic core domain 17 257 9.8E-14 T 14-10-2018 IPR025857 MacB-like periplasmic core domain Tharo_2055 214b1a6ebb5ca6ff47b4a349696d04a4 256 SUPERFAMILY SSF51161 1 256 2.73E-78 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily Tharo_2055 214b1a6ebb5ca6ff47b4a349696d04a4 256 Gene3D G3DSA:1.20.1180.10 191 256 5.4E-22 T 14-10-2018 IPR037157 UDP-N-acetylglucosamine O-acyltransferase, C-terminal domain superfamily KEGG: 00540+2.3.1.129 Tharo_2055 214b1a6ebb5ca6ff47b4a349696d04a4 256 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 174 255 6.9E-27 T 14-10-2018 IPR029098 UDP N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00540+2.3.1.129 Tharo_2055 214b1a6ebb5ca6ff47b4a349696d04a4 256 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 2 255 1.9E-100 T 14-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 Tharo_2055 214b1a6ebb5ca6ff47b4a349696d04a4 256 PIRSF PIRSF000456 1 256 1.5E-100 T 14-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 Tharo_2055 214b1a6ebb5ca6ff47b4a349696d04a4 256 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 2 33 1.8E-6 T 14-10-2018 IPR001451 Hexapeptide repeat Tharo_2055 214b1a6ebb5ca6ff47b4a349696d04a4 256 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 103 137 2.2E-9 T 14-10-2018 IPR001451 Hexapeptide repeat Tharo_2055 214b1a6ebb5ca6ff47b4a349696d04a4 256 Gene3D G3DSA:2.160.10.10 1 188 3.0E-55 T 14-10-2018 Tharo_2055 214b1a6ebb5ca6ff47b4a349696d04a4 256 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 1 256 43.623 T 14-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 Tharo_1354 8e94b6eee09d19a223d86d2a23af8bf5 309 SUPERFAMILY SSF88697 240 300 1.89E-5 T 14-10-2018 IPR015947 PUA-like superfamily Tharo_1354 8e94b6eee09d19a223d86d2a23af8bf5 309 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 32 179 7.3E-58 T 14-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 Tharo_1354 8e94b6eee09d19a223d86d2a23af8bf5 309 Gene3D G3DSA:2.30.130.10 242 302 1.1E-8 T 14-10-2018 IPR036974 PUA domain superfamily GO:0003723 Tharo_1354 8e94b6eee09d19a223d86d2a23af8bf5 309 Gene3D G3DSA:3.30.2350.10 2 241 1.0E-92 T 14-10-2018 Tharo_1354 8e94b6eee09d19a223d86d2a23af8bf5 309 SUPERFAMILY SSF55120 9 238 7.91E-84 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_1354 8e94b6eee09d19a223d86d2a23af8bf5 309 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 180 237 1.2E-15 T 14-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 Tharo_1354 8e94b6eee09d19a223d86d2a23af8bf5 309 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 241 299 3.0E-12 T 14-10-2018 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_1354 8e94b6eee09d19a223d86d2a23af8bf5 309 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 10 218 9.1E-82 T 14-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_1354 8e94b6eee09d19a223d86d2a23af8bf5 309 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 10 299 19.44 T 14-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_1149 c829308c574130b3c3631a04be6f613c 727 SUPERFAMILY SSF51645 2 724 9.68E-301 T 14-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 Tharo_1149 c829308c574130b3c3631a04be6f613c 727 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 4 724 0.0 T 14-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 Tharo_1149 c829308c574130b3c3631a04be6f613c 727 Gene3D G3DSA:3.20.20.360 7 582 8.1E-274 T 14-10-2018 Tharo_1149 c829308c574130b3c3631a04be6f613c 727 Gene3D G3DSA:1.20.1220.12 586 727 9.3E-74 T 14-10-2018 Tharo_1149 c829308c574130b3c3631a04be6f613c 727 Hamap MF_00641 Malate synthase G [glcB]. 1 727 402.39 T 14-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 Tharo_1149 c829308c574130b3c3631a04be6f613c 727 Pfam PF01274 Malate synthase 18 699 4.6E-167 T 14-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 Tharo_1149 c829308c574130b3c3631a04be6f613c 727 Gene3D G3DSA:2.170.170.11 135 264 8.1E-274 T 14-10-2018 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 Tharo_0850 d169b1e9c3eab3b4eda7d2ff5b75ba88 142 SUPERFAMILY SSF54637 5 137 7.15E-27 T 14-10-2018 IPR029069 HotDog domain superfamily Tharo_0850 d169b1e9c3eab3b4eda7d2ff5b75ba88 142 Pfam PF13279 Thioesterase-like superfamily 10 131 1.1E-8 T 14-10-2018 Tharo_0850 d169b1e9c3eab3b4eda7d2ff5b75ba88 142 Gene3D G3DSA:3.10.129.10 4 138 1.5E-27 T 14-10-2018 Tharo_1409 46b44ec87acaef5cc2689d1859153865 316 ProSitePatterns PS01053 Arginase family signature. 243 264 - T 14-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 Tharo_1409 46b44ec87acaef5cc2689d1859153865 316 Pfam PF00491 Arginase family 40 311 7.1E-62 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 Tharo_1409 46b44ec87acaef5cc2689d1859153865 316 Hamap MF_00737 Formimidoylglutamase [hutG]. 6 314 41.598 T 14-10-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 Tharo_1409 46b44ec87acaef5cc2689d1859153865 316 SUPERFAMILY SSF52768 23 310 1.37E-79 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily Tharo_1409 46b44ec87acaef5cc2689d1859153865 316 Gene3D G3DSA:3.40.800.10 2 315 1.1E-112 T 14-10-2018 Tharo_1409 46b44ec87acaef5cc2689d1859153865 316 PIRSF PIRSF036979 26 314 3.5E-27 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 Tharo_1409 46b44ec87acaef5cc2689d1859153865 316 PRINTS PR00116 Arginase signature 240 269 6.9E-7 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 Tharo_1409 46b44ec87acaef5cc2689d1859153865 316 PRINTS PR00116 Arginase signature 119 134 6.9E-7 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 Tharo_1409 46b44ec87acaef5cc2689d1859153865 316 PRINTS PR00116 Arginase signature 275 289 6.9E-7 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 Tharo_1409 46b44ec87acaef5cc2689d1859153865 316 TIGRFAM TIGR01227 hutG: formimidoylglutamase 11 310 2.3E-97 T 14-10-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 Tharo_0341 ed7f62d0f6988d2aaae94032301a87bb 264 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 203 222 2.5E-26 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 Tharo_0341 ed7f62d0f6988d2aaae94032301a87bb 264 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 81 100 2.5E-26 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 Tharo_0341 ed7f62d0f6988d2aaae94032301a87bb 264 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 181 203 2.5E-26 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 Tharo_0341 ed7f62d0f6988d2aaae94032301a87bb 264 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 22 43 2.5E-26 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 Tharo_0341 ed7f62d0f6988d2aaae94032301a87bb 264 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 14 256 8.4E-66 T 14-10-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 Tharo_0341 ed7f62d0f6988d2aaae94032301a87bb 264 Pfam PF01311 Bacterial export proteins, family 1 14 246 7.6E-64 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 Tharo_2237 3fb7f1442752abf0e324c548b8bbe77d 193 Pfam PF10741 Type II secretion system (T2SS), protein M subtype b 80 190 2.3E-24 T 14-10-2018 IPR034756 Type II secretion system (T2SS), protein M subtype b Tharo_2391 74b27133acd0099d4212e37f630f483c 104 Pfam PF00462 Glutaredoxin 21 80 2.5E-17 T 14-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 Tharo_2391 74b27133acd0099d4212e37f630f483c 104 PRINTS PR00160 Glutaredoxin signature 20 38 3.8E-16 T 14-10-2018 IPR014025 Glutaredoxin subgroup Tharo_2391 74b27133acd0099d4212e37f630f483c 104 PRINTS PR00160 Glutaredoxin signature 77 90 3.8E-16 T 14-10-2018 IPR014025 Glutaredoxin subgroup Tharo_2391 74b27133acd0099d4212e37f630f483c 104 PRINTS PR00160 Glutaredoxin signature 63 76 3.8E-16 T 14-10-2018 IPR014025 Glutaredoxin subgroup Tharo_2391 74b27133acd0099d4212e37f630f483c 104 SUPERFAMILY SSF52833 15 101 5.55E-25 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_2391 74b27133acd0099d4212e37f630f483c 104 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 20 99 4.3E-33 T 14-10-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 Tharo_2391 74b27133acd0099d4212e37f630f483c 104 Gene3D G3DSA:3.40.30.10 15 102 5.6E-23 T 14-10-2018 Tharo_2391 74b27133acd0099d4212e37f630f483c 104 ProSitePatterns PS00195 Glutaredoxin active site. 22 38 - T 14-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 Tharo_1174 3c7e5964272fd0891750d6fa10170d78 560 Gene3D G3DSA:3.40.50.12780 13 457 6.1E-121 T 14-10-2018 Tharo_1174 3c7e5964272fd0891750d6fa10170d78 560 SUPERFAMILY SSF56801 22 554 8.11E-158 T 14-10-2018 Tharo_1174 3c7e5964272fd0891750d6fa10170d78 560 ProSitePatterns PS00455 Putative AMP-binding domain signature. 211 222 - T 14-10-2018 IPR020845 AMP-binding, conserved site Tharo_1174 3c7e5964272fd0891750d6fa10170d78 560 Pfam PF13193 AMP-binding enzyme C-terminal domain 470 544 1.2E-19 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Tharo_1174 3c7e5964272fd0891750d6fa10170d78 560 Pfam PF00501 AMP-binding enzyme 29 461 5.9E-112 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Tharo_1174 3c7e5964272fd0891750d6fa10170d78 560 Gene3D G3DSA:3.30.300.310 458 558 1.1E-31 T 14-10-2018 Tharo_2215 1c80916973be15a310b86606c6e6b88c 112 Pfam PF00034 Cytochrome c 30 102 4.8E-6 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_2215 1c80916973be15a310b86606c6e6b88c 112 SUPERFAMILY SSF46626 24 105 1.86E-22 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_2215 1c80916973be15a310b86606c6e6b88c 112 Gene3D G3DSA:1.10.760.10 28 105 6.4E-26 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_1439 596c78f842c4e4ef219d769308d47f49 228 Pfam PF00155 Aminotransferase class I and II 37 217 2.2E-14 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Tharo_1439 596c78f842c4e4ef219d769308d47f49 228 Gene3D G3DSA:3.40.640.10 34 120 1.3E-52 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_1439 596c78f842c4e4ef219d769308d47f49 228 SUPERFAMILY SSF53383 34 226 1.82E-46 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_1439 596c78f842c4e4ef219d769308d47f49 228 Gene3D G3DSA:3.90.1150.10 122 225 1.3E-52 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_2554 90879e199fe2ef82c6cdebe51a681eb1 583 Gene3D G3DSA:3.40.980.10 186 331 3.4E-15 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily Tharo_2554 90879e199fe2ef82c6cdebe51a681eb1 583 PIRSF PIRSF036626 374 583 1.0E-58 T 14-10-2018 IPR012184 Bifunctional molybdopterin binding protein /nucleotidyl transferase, putative Tharo_2554 90879e199fe2ef82c6cdebe51a681eb1 583 PIRSF PIRSF036626 160 368 4.3E-48 T 14-10-2018 IPR012184 Bifunctional molybdopterin binding protein /nucleotidyl transferase, putative Tharo_2554 90879e199fe2ef82c6cdebe51a681eb1 583 PIRSF PIRSF036626 1 168 3.3E-40 T 14-10-2018 IPR012184 Bifunctional molybdopterin binding protein /nucleotidyl transferase, putative Tharo_2554 90879e199fe2ef82c6cdebe51a681eb1 583 Pfam PF12804 MobA-like NTP transferase domain 393 555 5.7E-43 T 14-10-2018 IPR025877 MobA-like NTP transferase Tharo_2554 90879e199fe2ef82c6cdebe51a681eb1 583 SUPERFAMILY SSF53448 389 577 4.51E-35 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_2554 90879e199fe2ef82c6cdebe51a681eb1 583 SUPERFAMILY SSF53218 197 331 3.01E-18 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily Tharo_2554 90879e199fe2ef82c6cdebe51a681eb1 583 Gene3D G3DSA:3.90.550.10 389 581 1.2E-58 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_2554 90879e199fe2ef82c6cdebe51a681eb1 583 SMART SM00852 195 329 0.0073 T 14-10-2018 IPR001453 MoaB/Mog domain Tharo_0959 1a51aacc3f34f9b3dc3b8a97b6b02c4f 582 Gene3D G3DSA:1.20.1560.10 10 318 8.5E-25 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Tharo_0959 1a51aacc3f34f9b3dc3b8a97b6b02c4f 582 TIGRFAM TIGR01842 type_I_sec_PrtD: type I secretion system ATPase 17 558 2.2E-191 T 14-10-2018 IPR010128 ATPase, type I secretion system, PrtD GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 Tharo_0959 1a51aacc3f34f9b3dc3b8a97b6b02c4f 582 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_0959 1a51aacc3f34f9b3dc3b8a97b6b02c4f 582 Pfam PF00664 ABC transporter transmembrane region 41 268 1.3E-8 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Tharo_0959 1a51aacc3f34f9b3dc3b8a97b6b02c4f 582 Pfam PF00005 ABC transporter 349 496 4.7E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_0959 1a51aacc3f34f9b3dc3b8a97b6b02c4f 582 Gene3D G3DSA:3.40.50.300 321 566 1.6E-65 T 14-10-2018 Tharo_0959 1a51aacc3f34f9b3dc3b8a97b6b02c4f 582 SUPERFAMILY SSF52540 322 556 3.68E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0959 1a51aacc3f34f9b3dc3b8a97b6b02c4f 582 SMART SM00382 358 544 5.3E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0959 1a51aacc3f34f9b3dc3b8a97b6b02c4f 582 SUPERFAMILY SSF90123 10 320 1.29E-35 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Tharo_0996 61b87c6fddb848564b0e949e8535ecad 78 Gene3D G3DSA:2.30.30.100 1 78 9.0E-33 T 14-10-2018 Tharo_0996 61b87c6fddb848564b0e949e8535ecad 78 SUPERFAMILY SSF50182 8 68 1.04E-23 T 14-10-2018 IPR010920 LSM domain superfamily Tharo_0996 61b87c6fddb848564b0e949e8535ecad 78 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 8 65 5.2E-29 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 Tharo_0996 61b87c6fddb848564b0e949e8535ecad 78 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 65 27.867 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 Tharo_0996 61b87c6fddb848564b0e949e8535ecad 78 Pfam PF17209 Hfq protein 8 69 1.7E-31 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 Tharo_3342 717b21547bfafc064f34ee4298641202 240 SUPERFAMILY SSF52141 6 238 4.91E-59 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Tharo_3342 717b21547bfafc064f34ee4298641202 240 Gene3D G3DSA:3.40.470.10 1 240 1.9E-95 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Tharo_1965 7397286359409ee9169c7332b2091ae8 266 Gene3D G3DSA:3.90.226.10 11 208 2.8E-68 T 14-10-2018 Tharo_1965 7397286359409ee9169c7332b2091ae8 266 Gene3D G3DSA:1.10.12.10 209 266 1.8E-21 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal Tharo_1965 7397286359409ee9169c7332b2091ae8 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 265 2.6E-56 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Tharo_1965 7397286359409ee9169c7332b2091ae8 266 SUPERFAMILY SSF52096 9 265 2.87E-79 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_3443 59551c66690166432546e4d1cf768530 225 PRINTS PR00400 Tetracycline repressor protein signature 193 207 1.9E-51 T 14-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 Tharo_3443 59551c66690166432546e4d1cf768530 225 PRINTS PR00400 Tetracycline repressor protein signature 104 127 1.9E-51 T 14-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 Tharo_3443 59551c66690166432546e4d1cf768530 225 PRINTS PR00400 Tetracycline repressor protein signature 84 103 1.9E-51 T 14-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 Tharo_3443 59551c66690166432546e4d1cf768530 225 PRINTS PR00400 Tetracycline repressor protein signature 30 53 1.9E-51 T 14-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 Tharo_3443 59551c66690166432546e4d1cf768530 225 PRINTS PR00400 Tetracycline repressor protein signature 139 158 1.9E-51 T 14-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 Tharo_3443 59551c66690166432546e4d1cf768530 225 SUPERFAMILY SSF48498 78 210 2.45E-35 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Tharo_3443 59551c66690166432546e4d1cf768530 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 1.4E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_3443 59551c66690166432546e4d1cf768530 225 Gene3D G3DSA:1.10.10.60 10 75 5.2E-29 T 14-10-2018 Tharo_3443 59551c66690166432546e4d1cf768530 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.7E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_3443 59551c66690166432546e4d1cf768530 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.7E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_3443 59551c66690166432546e4d1cf768530 225 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 61 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Tharo_3443 59551c66690166432546e4d1cf768530 225 SUPERFAMILY SSF46689 16 74 8.72E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_3443 59551c66690166432546e4d1cf768530 225 Gene3D G3DSA:1.10.357.10 76 213 6.7E-36 T 14-10-2018 Tharo_3443 59551c66690166432546e4d1cf768530 225 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 78 210 1.4E-40 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 Tharo_2808 6e830e5c587c3d901c0f99b0882e4e3e 428 Pfam PF12704 MacB-like periplasmic core domain 20 201 1.5E-12 T 14-10-2018 IPR025857 MacB-like periplasmic core domain Tharo_2808 6e830e5c587c3d901c0f99b0882e4e3e 428 Pfam PF02687 FtsX-like permease family 326 419 1.5E-10 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Tharo_3195 6d5126273a919e2273441f812a773a7b 590 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 478 507 6.5E-46 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_3195 6d5126273a919e2273441f812a773a7b 590 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 401 428 6.5E-46 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_3195 6d5126273a919e2273441f812a773a7b 590 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 324 353 6.5E-46 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_3195 6d5126273a919e2273441f812a773a7b 590 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 430 459 6.5E-46 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_3195 6d5126273a919e2273441f812a773a7b 590 Gene3D G3DSA:3.30.450.20 49 221 1.4E-45 T 14-10-2018 Tharo_3195 6d5126273a919e2273441f812a773a7b 590 SMART SM00304 244 302 7.4E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_3195 6d5126273a919e2273441f812a773a7b 590 SMART SM01049 61 151 2.1E-27 T 14-10-2018 IPR033480 Single Cache domain 2 Tharo_3195 6d5126273a919e2273441f812a773a7b 590 Pfam PF17200 Single Cache domain 2 66 210 5.3E-42 T 14-10-2018 IPR033480 Single Cache domain 2 Tharo_3195 6d5126273a919e2273441f812a773a7b 590 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 363 517 1.1E-47 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_3195 6d5126273a919e2273441f812a773a7b 590 SMART SM00283 303 550 2.6E-86 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_3195 6d5126273a919e2273441f812a773a7b 590 SUPERFAMILY SSF58104 270 550 6.54E-69 T 14-10-2018 Tharo_3195 6d5126273a919e2273441f812a773a7b 590 Gene3D G3DSA:1.10.287.950 243 551 3.0E-81 T 14-10-2018 Tharo_3195 6d5126273a919e2273441f812a773a7b 590 Pfam PF00672 HAMP domain 244 299 1.6E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_3156 540593021e5558f72121c0a1a16bb8c1 249 Gene3D G3DSA:3.40.190.10 103 209 4.6E-75 T 14-10-2018 Tharo_3156 540593021e5558f72121c0a1a16bb8c1 249 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 29 246 3.0E-64 T 14-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 Tharo_3156 540593021e5558f72121c0a1a16bb8c1 249 Pfam PF13531 Bacterial extracellular solute-binding protein 25 248 7.4E-47 T 14-10-2018 Tharo_3156 540593021e5558f72121c0a1a16bb8c1 249 Gene3D G3DSA:3.40.190.10 28 247 4.6E-75 T 14-10-2018 Tharo_3156 540593021e5558f72121c0a1a16bb8c1 249 SUPERFAMILY SSF53850 23 248 4.04E-57 T 14-10-2018 Tharo_3156 540593021e5558f72121c0a1a16bb8c1 249 PIRSF PIRSF004846 2 249 7.8E-42 T 14-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 Tharo_0482 353ff8a7aa0171d37b16fca7f328cab4 188 SUPERFAMILY SSF143456 7 188 1.44E-64 T 14-10-2018 Tharo_0482 353ff8a7aa0171d37b16fca7f328cab4 188 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 6 188 37.508 T 14-10-2018 IPR003774 Protein of unknown function UPF0301 Tharo_0482 353ff8a7aa0171d37b16fca7f328cab4 188 Gene3D G3DSA:3.40.1740.10 4 188 1.2E-66 T 14-10-2018 Tharo_0482 353ff8a7aa0171d37b16fca7f328cab4 188 Pfam PF02622 Uncharacterized ACR, COG1678 17 175 1.3E-47 T 14-10-2018 IPR003774 Protein of unknown function UPF0301 Tharo_0376 dcc8fb2ab6a5661994582f7b2ef37005 103 Gene3D G3DSA:1.10.260.40 26 103 2.7E-15 T 14-10-2018 Tharo_0376 dcc8fb2ab6a5661994582f7b2ef37005 103 SUPERFAMILY SSF47413 40 98 6.82E-12 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_0376 dcc8fb2ab6a5661994582f7b2ef37005 103 Pfam PF01381 Helix-turn-helix 44 97 3.9E-13 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_0376 dcc8fb2ab6a5661994582f7b2ef37005 103 SMART SM00530 42 101 9.1E-12 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_2368 d92e0f4ece59fd606ded68c56ec057b7 183 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 9 178 5.7E-58 T 14-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 Tharo_2368 d92e0f4ece59fd606ded68c56ec057b7 183 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 24 179 1.0E-47 T 14-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 Tharo_2368 d92e0f4ece59fd606ded68c56ec057b7 183 Gene3D G3DSA:1.20.1200.10 17 183 1.4E-60 T 14-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 Tharo_2368 d92e0f4ece59fd606ded68c56ec057b7 183 SUPERFAMILY SSF89028 7 178 8.63E-61 T 14-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 Tharo_2368 d92e0f4ece59fd606ded68c56ec057b7 183 Pfam PF01923 Cobalamin adenosyltransferase 8 165 2.9E-55 T 14-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 Tharo_0020 38ee8c23812e0729de12747025b756e7 724 SUPERFAMILY SSF48113 19 431 6.48E-152 T 14-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 Tharo_0020 38ee8c23812e0729de12747025b756e7 724 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 26 48 3.9E-51 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 Tharo_0020 38ee8c23812e0729de12747025b756e7 724 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 478 504 3.9E-51 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 Tharo_0020 38ee8c23812e0729de12747025b756e7 724 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 267 290 3.9E-51 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 Tharo_0020 38ee8c23812e0729de12747025b756e7 724 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 52 65 3.9E-51 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 Tharo_0020 38ee8c23812e0729de12747025b756e7 724 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 67 92 3.9E-51 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 Tharo_0020 38ee8c23812e0729de12747025b756e7 724 Pfam PF00141 Peroxidase 405 698 7.5E-36 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 Tharo_0020 38ee8c23812e0729de12747025b756e7 724 Pfam PF00141 Peroxidase 70 398 5.4E-52 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 Tharo_0020 38ee8c23812e0729de12747025b756e7 724 SUPERFAMILY SSF48113 432 723 5.16E-110 T 14-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 Tharo_0020 38ee8c23812e0729de12747025b756e7 724 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 11 723 0.0 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 Tharo_0020 38ee8c23812e0729de12747025b756e7 724 Gene3D G3DSA:1.10.420.20 191 397 2.8E-218 T 14-10-2018 Tharo_0020 38ee8c23812e0729de12747025b756e7 724 Gene3D G3DSA:1.10.420.10 578 699 3.7E-147 T 14-10-2018 Tharo_0020 38ee8c23812e0729de12747025b756e7 724 ProSitePatterns PS00436 Peroxidases active site signature. 90 101 - T 14-10-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 Tharo_0020 38ee8c23812e0729de12747025b756e7 724 Gene3D G3DSA:1.10.520.10 28 432 2.8E-218 T 14-10-2018 Tharo_0020 38ee8c23812e0729de12747025b756e7 724 Hamap MF_01961 Catalase-peroxidase [katG]. 7 724 40.146 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 Tharo_0020 38ee8c23812e0729de12747025b756e7 724 Gene3D G3DSA:1.10.520.10 433 723 3.7E-147 T 14-10-2018 Tharo_0020 38ee8c23812e0729de12747025b756e7 724 PRINTS PR00458 Haem peroxidase superfamily signature 150 167 2.3E-19 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 Tharo_0020 38ee8c23812e0729de12747025b756e7 724 PRINTS PR00458 Haem peroxidase superfamily signature 168 180 2.3E-19 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 Tharo_0020 38ee8c23812e0729de12747025b756e7 724 PRINTS PR00458 Haem peroxidase superfamily signature 90 104 2.3E-19 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 Tharo_0020 38ee8c23812e0729de12747025b756e7 724 PRINTS PR00458 Haem peroxidase superfamily signature 318 333 2.3E-19 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 Tharo_0020 38ee8c23812e0729de12747025b756e7 724 PRINTS PR00458 Haem peroxidase superfamily signature 259 274 2.3E-19 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 Tharo_1447 dcb04f004a243419f5ed1210913af2e2 647 SUPERFAMILY SSF49503 514 646 1.06E-28 T 14-10-2018 IPR008972 Cupredoxin Tharo_1447 dcb04f004a243419f5ed1210913af2e2 647 TIGRFAM TIGR04244 nitrous_NosZ_RR: nitrous-oxide reductase, TAT-dependent 15 646 6.5E-301 T 14-10-2018 IPR023644 Nitrous-oxide reductase GO:0005507|GO:0005509|GO:0050304|GO:0055114 KEGG: 00910+1.7.2.4|MetaCyc: PWY-6748|MetaCyc: PWY-7084 Tharo_1447 dcb04f004a243419f5ed1210913af2e2 647 SUPERFAMILY SSF50974 66 525 3.4E-122 T 14-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 Tharo_1447 dcb04f004a243419f5ed1210913af2e2 647 Pfam PF13473 Cupredoxin-like domain 553 645 1.3E-6 T 14-10-2018 IPR028096 EfeO-type cupredoxin-like domain Tharo_1447 dcb04f004a243419f5ed1210913af2e2 647 Gene3D G3DSA:2.130.10.10 66 535 2.5E-181 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Tharo_1447 dcb04f004a243419f5ed1210913af2e2 647 Gene3D G3DSA:2.60.40.420 536 647 9.4E-32 T 14-10-2018 IPR008972 Cupredoxin Tharo_2060 f1c37f27bdb81187cf353951eef629e0 454 Pfam PF02163 Peptidase family M50 10 439 2.1E-82 T 14-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 Tharo_2060 f1c37f27bdb81187cf353951eef629e0 454 SUPERFAMILY SSF50156 214 293 1.13E-12 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 Tharo_2060 f1c37f27bdb81187cf353951eef629e0 454 Gene3D G3DSA:2.30.42.10 221 309 2.8E-18 T 14-10-2018 Tharo_2060 f1c37f27bdb81187cf353951eef629e0 454 Gene3D G3DSA:2.30.42.10 127 220 3.7E-11 T 14-10-2018 Tharo_2060 f1c37f27bdb81187cf353951eef629e0 454 SMART SM00228 115 187 1.0 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Tharo_2060 f1c37f27bdb81187cf353951eef629e0 454 SMART SM00228 196 280 4.9E-6 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Tharo_2060 f1c37f27bdb81187cf353951eef629e0 454 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 2 452 1.3E-113 T 14-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 Tharo_2060 f1c37f27bdb81187cf353951eef629e0 454 SUPERFAMILY SSF50156 86 184 3.55E-9 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 Tharo_1873 d5b54e9b5d92ab3034f94956db6902c9 388 Gene3D G3DSA:1.20.140.10 238 382 9.3E-45 T 14-10-2018 Tharo_1873 d5b54e9b5d92ab3034f94956db6902c9 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 221 7.6E-22 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Tharo_1873 d5b54e9b5d92ab3034f94956db6902c9 388 Gene3D G3DSA:1.10.540.10 8 125 5.0E-27 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Tharo_1873 d5b54e9b5d92ab3034f94956db6902c9 388 Gene3D G3DSA:2.40.110.10 127 237 3.2E-44 T 14-10-2018 Tharo_1873 d5b54e9b5d92ab3034f94956db6902c9 388 SUPERFAMILY SSF47203 232 384 4.67E-49 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Tharo_1873 d5b54e9b5d92ab3034f94956db6902c9 388 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 130 142 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Tharo_1873 d5b54e9b5d92ab3034f94956db6902c9 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 381 2.2E-44 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Tharo_1873 d5b54e9b5d92ab3034f94956db6902c9 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 123 1.1E-13 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Tharo_1873 d5b54e9b5d92ab3034f94956db6902c9 388 SUPERFAMILY SSF56645 11 244 1.02E-58 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Tharo_0741 473ea70249b5cf56fb722404e0e8b977 291 SUPERFAMILY SSF52540 1 267 2.79E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0741 473ea70249b5cf56fb722404e0e8b977 291 Pfam PF13614 AAA domain 1 168 2.9E-24 T 14-10-2018 IPR025669 AAA domain Tharo_0741 473ea70249b5cf56fb722404e0e8b977 291 Gene3D G3DSA:3.40.50.300 1 274 3.3E-46 T 14-10-2018 Tharo_0315 2c5588007973bfc36da003efb9511657 538 Pfam PF03050 Transposase IS66 family 205 486 8.3E-95 T 14-10-2018 IPR004291 Transposase, IS66 Tharo_0315 2c5588007973bfc36da003efb9511657 538 Pfam PF13005 zinc-finger binding domain of transposase IS66 147 190 7.5E-18 T 14-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 Tharo_0315 2c5588007973bfc36da003efb9511657 538 Pfam PF13007 Transposase C of IS166 homeodomain 61 139 7.4E-11 T 14-10-2018 IPR024463 Transposase TnpC, homeodomain Tharo_0315 2c5588007973bfc36da003efb9511657 538 Pfam PF13817 IS66 C-terminal element 493 529 2.3E-13 T 14-10-2018 IPR039552 Transposase IS66, C-terminal Tharo_2613 78cae5ad88080464b59c883700707778 143 SUPERFAMILY SSF52980 1 68 9.12E-13 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Tharo_2613 78cae5ad88080464b59c883700707778 143 Gene3D G3DSA:3.30.65.10 79 143 9.1E-6 T 14-10-2018 Tharo_2613 78cae5ad88080464b59c883700707778 143 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 100 137 5.7E-9 T 14-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 Tharo_2613 78cae5ad88080464b59c883700707778 143 Pfam PF04471 Restriction endonuclease 1 64 8.3E-16 T 14-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 Tharo_2613 78cae5ad88080464b59c883700707778 143 SUPERFAMILY SSF57783 92 139 1.31E-7 T 14-10-2018 Tharo_0220 dc5808cc9cf737d6e88912c8cbf08967 59 Gene3D G3DSA:3.40.1620.10 1 25 1.8E-8 T 14-10-2018 Tharo_0220 dc5808cc9cf737d6e88912c8cbf08967 59 SUPERFAMILY SSF143120 2 34 3.27E-5 T 14-10-2018 IPR036165 YefM-like superfamily Tharo_0220 dc5808cc9cf737d6e88912c8cbf08967 59 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 2 25 6.7E-7 T 14-10-2018 Tharo_0220 dc5808cc9cf737d6e88912c8cbf08967 59 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 2 39 6.0E-9 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Tharo_1121 01be2b310b2f34cf978bf3f4f7a4783c 419 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 23 416 3.6E-112 T 14-10-2018 IPR002155 Thiolase GO:0016747 Tharo_1121 01be2b310b2f34cf978bf3f4f7a4783c 419 SUPERFAMILY SSF53901 296 417 2.08E-37 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_1121 01be2b310b2f34cf978bf3f4f7a4783c 419 Pfam PF02803 Thiolase, C-terminal domain 295 416 2.0E-42 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 Tharo_1121 01be2b310b2f34cf978bf3f4f7a4783c 419 ProSitePatterns PS00099 Thiolases active site. 399 412 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 Tharo_1121 01be2b310b2f34cf978bf3f4f7a4783c 419 SUPERFAMILY SSF53901 19 295 4.76E-61 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_1121 01be2b310b2f34cf978bf3f4f7a4783c 419 Pfam PF00108 Thiolase, N-terminal domain 21 286 8.0E-57 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 Tharo_1121 01be2b310b2f34cf978bf3f4f7a4783c 419 Gene3D G3DSA:3.40.47.10 143 415 1.9E-125 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_1121 01be2b310b2f34cf978bf3f4f7a4783c 419 ProSitePatterns PS00737 Thiolases signature 2. 364 380 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 Tharo_1121 01be2b310b2f34cf978bf3f4f7a4783c 419 Gene3D G3DSA:3.40.47.10 23 301 1.9E-125 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_1121 01be2b310b2f34cf978bf3f4f7a4783c 419 PIRSF PIRSF000429 15 419 2.0E-108 T 14-10-2018 IPR002155 Thiolase GO:0016747 Tharo_0069 171872a54b3d00ca4707629712cab5ad 969 Pfam PF13244 Domain of unknown function (DUF4040) 614 675 2.4E-18 T 14-10-2018 IPR025383 Domain of unknown function DUF4040 Tharo_0069 171872a54b3d00ca4707629712cab5ad 969 Pfam PF00361 Proton-conducting membrane transporter 126 405 2.2E-66 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_0069 171872a54b3d00ca4707629712cab5ad 969 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 815 935 1.7E-30 T 14-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein Tharo_0069 171872a54b3d00ca4707629712cab5ad 969 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 60 113 2.4E-11 T 14-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_0069 171872a54b3d00ca4707629712cab5ad 969 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 75 100 9.1E-41 T 14-10-2018 Tharo_0069 171872a54b3d00ca4707629712cab5ad 969 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 150 171 9.1E-41 T 14-10-2018 Tharo_0069 171872a54b3d00ca4707629712cab5ad 969 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 103 123 9.1E-41 T 14-10-2018 Tharo_0069 171872a54b3d00ca4707629712cab5ad 969 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 9.1E-41 T 14-10-2018 Tharo_0069 171872a54b3d00ca4707629712cab5ad 969 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 413 432 9.1E-41 T 14-10-2018 Tharo_0069 171872a54b3d00ca4707629712cab5ad 969 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 238 264 9.1E-41 T 14-10-2018 Tharo_0069 171872a54b3d00ca4707629712cab5ad 969 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 306 318 9.1E-41 T 14-10-2018 Tharo_1389 f2184521c082540721d617a951f135af 118 Gene3D G3DSA:1.20.120.160 7 118 2.7E-20 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 Tharo_1389 f2184521c082540721d617a951f135af 118 Pfam PF01627 Hpt domain 29 103 3.2E-10 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Tharo_1389 f2184521c082540721d617a951f135af 118 SUPERFAMILY SSF47226 4 117 6.41E-20 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 Tharo_1389 f2184521c082540721d617a951f135af 118 SMART SM00073 19 114 0.0034 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Tharo_2990 efc9791759b097bac6192d2fc6899b9c 228 SUPERFAMILY SSF53271 18 224 6.82E-45 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Tharo_2990 efc9791759b097bac6192d2fc6899b9c 228 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 26 199 3.0E-50 T 14-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Tharo_2990 efc9791759b097bac6192d2fc6899b9c 228 Pfam PF00156 Phosphoribosyl transferase domain 52 176 7.7E-13 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Tharo_2990 efc9791759b097bac6192d2fc6899b9c 228 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 228 32.617 T 14-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Tharo_2990 efc9791759b097bac6192d2fc6899b9c 228 Gene3D G3DSA:3.40.50.2020 15 225 2.9E-67 T 14-10-2018 Tharo_0102 3e89905a74cd4f8cc53d622ced199ca9 387 Gene3D G3DSA:1.10.540.10 1 123 1.2E-29 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Tharo_0102 3e89905a74cd4f8cc53d622ced199ca9 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 212 4.5E-9 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Tharo_0102 3e89905a74cd4f8cc53d622ced199ca9 387 Gene3D G3DSA:1.20.140.10 238 386 2.0E-30 T 14-10-2018 Tharo_0102 3e89905a74cd4f8cc53d622ced199ca9 387 SUPERFAMILY SSF47203 240 385 3.7E-34 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Tharo_0102 3e89905a74cd4f8cc53d622ced199ca9 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 245 372 8.0E-25 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Tharo_0102 3e89905a74cd4f8cc53d622ced199ca9 387 SUPERFAMILY SSF56645 1 224 1.57E-48 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Tharo_0102 3e89905a74cd4f8cc53d622ced199ca9 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 121 1.1E-19 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Tharo_0102 3e89905a74cd4f8cc53d622ced199ca9 387 Gene3D G3DSA:2.40.110.10 125 233 1.1E-15 T 14-10-2018 Tharo_2330 04e23b9156c87d3ebff55edb236a84b8 399 Gene3D G3DSA:1.10.240.10 218 326 3.7E-31 T 14-10-2018 Tharo_2330 04e23b9156c87d3ebff55edb236a84b8 399 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 2 398 48.613 T 14-10-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 Tharo_2330 04e23b9156c87d3ebff55edb236a84b8 399 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 6 397 4.1E-122 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Tharo_2330 04e23b9156c87d3ebff55edb236a84b8 399 SUPERFAMILY SSF52374 7 316 1.39E-98 T 14-10-2018 Tharo_2330 04e23b9156c87d3ebff55edb236a84b8 399 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_2330 04e23b9156c87d3ebff55edb236a84b8 399 SUPERFAMILY SSF55174 321 398 1.7E-19 T 14-10-2018 Tharo_2330 04e23b9156c87d3ebff55edb236a84b8 399 Gene3D G3DSA:3.40.50.620 5 217 1.0E-73 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_2330 04e23b9156c87d3ebff55edb236a84b8 399 Gene3D G3DSA:3.10.290.10 327 397 2.4E-18 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Tharo_2330 04e23b9156c87d3ebff55edb236a84b8 399 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 46 68 4.7E-24 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Tharo_2330 04e23b9156c87d3ebff55edb236a84b8 399 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 211 223 4.7E-24 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Tharo_2330 04e23b9156c87d3ebff55edb236a84b8 399 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 161 176 4.7E-24 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Tharo_2330 04e23b9156c87d3ebff55edb236a84b8 399 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 178 200 4.7E-24 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Tharo_2330 04e23b9156c87d3ebff55edb236a84b8 399 SMART SM00363 337 399 4.2E-9 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2330 04e23b9156c87d3ebff55edb236a84b8 399 Pfam PF01479 S4 domain 338 384 1.2E-8 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2330 04e23b9156c87d3ebff55edb236a84b8 399 Pfam PF00579 tRNA synthetases class I (W and Y) 31 317 1.9E-76 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_1525 94d95eeba8e2b0f150af05747b4691e2 362 Gene3D G3DSA:3.20.20.70 28 362 3.6E-101 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_1525 94d95eeba8e2b0f150af05747b4691e2 362 SUPERFAMILY SSF102114 32 330 4.05E-79 T 14-10-2018 Tharo_1525 94d95eeba8e2b0f150af05747b4691e2 362 Pfam PF13394 4Fe-4S single cluster domain 47 133 8.2E-6 T 14-10-2018 Tharo_1525 94d95eeba8e2b0f150af05747b4691e2 362 SMART SM00729 40 248 1.0E-14 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Tharo_1525 94d95eeba8e2b0f150af05747b4691e2 362 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 31 362 2.8E-118 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Tharo_1525 94d95eeba8e2b0f150af05747b4691e2 362 Pfam PF06463 Molybdenum Cofactor Synthesis C 217 342 1.6E-38 T 14-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Tharo_1525 94d95eeba8e2b0f150af05747b4691e2 362 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 31 362 40.647 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Tharo_1525 94d95eeba8e2b0f150af05747b4691e2 362 Pfam PF04055 Radical SAM superfamily 44 207 2.3E-36 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_1525 94d95eeba8e2b0f150af05747b4691e2 362 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 46 57 - T 14-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Tharo_1308 54e2182ddfa3f6ef9ea6a64c982939e8 282 TIGRFAM TIGR02261 benz_CoA_red_D: benzoyl-CoA reductase, subunit D 2 263 2.9E-172 T 14-10-2018 IPR011956 Benzoyl-CoA reductase, subunit D KEGG: 00362+1.3.7.8 Tharo_1308 54e2182ddfa3f6ef9ea6a64c982939e8 282 Gene3D G3DSA:3.30.420.40 6 262 1.8E-54 T 14-10-2018 Tharo_1308 54e2182ddfa3f6ef9ea6a64c982939e8 282 SUPERFAMILY SSF53067 4 265 1.21E-25 T 14-10-2018 Tharo_1308 54e2182ddfa3f6ef9ea6a64c982939e8 282 Gene3D G3DSA:3.30.420.40 100 246 1.8E-54 T 14-10-2018 Tharo_1308 54e2182ddfa3f6ef9ea6a64c982939e8 282 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 6 263 5.7E-67 T 14-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 Tharo_1308 54e2182ddfa3f6ef9ea6a64c982939e8 282 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 3 261 1.2E-45 T 14-10-2018 IPR008275 CoA enzyme activase Tharo_0213 53cfd6496f2741dccce2ee693355882e 78 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 39 4.8E-8 T 14-10-2018 Tharo_0213 53cfd6496f2741dccce2ee693355882e 78 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 69 1.4E-11 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Tharo_0213 53cfd6496f2741dccce2ee693355882e 78 Gene3D G3DSA:3.40.1620.10 1 39 5.0E-11 T 14-10-2018 Tharo_0213 53cfd6496f2741dccce2ee693355882e 78 SUPERFAMILY SSF143120 1 40 2.35E-9 T 14-10-2018 IPR036165 YefM-like superfamily Tharo_2706 edbd4442530ab0706971f3687b9140de 60 SUPERFAMILY SSF55129 4 59 1.57E-20 T 14-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily Tharo_2706 edbd4442530ab0706971f3687b9140de 60 Pfam PF00327 Ribosomal protein L30p/L7e 6 55 6.5E-19 T 14-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain Tharo_2706 edbd4442530ab0706971f3687b9140de 60 Gene3D G3DSA:3.30.1390.20 2 59 1.6E-25 T 14-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily Tharo_2706 edbd4442530ab0706971f3687b9140de 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 3 60 21.127 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2706 edbd4442530ab0706971f3687b9140de 60 PIRSF PIRSF002211 1 60 2.0E-27 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2706 edbd4442530ab0706971f3687b9140de 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 6 59 4.7E-25 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2875 cd9c24808ecb368df93e688abede57eb 222 TIGRFAM TIGR02796 tolQ: protein TolQ 8 219 3.4E-83 T 14-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 Tharo_2875 cd9c24808ecb368df93e688abede57eb 222 Pfam PF01618 MotA/TolQ/ExbB proton channel family 78 207 1.9E-41 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel Tharo_2875 cd9c24808ecb368df93e688abede57eb 222 Hamap MF_02202 Tol-Pal system protein TolQ [tolQ]. 7 222 39.523 T 14-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 Tharo_0960 260bb4b512474d625ec2e897e114d282 584 Pfam PF00005 ABC transporter 351 498 8.2E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_0960 260bb4b512474d625ec2e897e114d282 584 SUPERFAMILY SSF52540 325 558 7.35E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0960 260bb4b512474d625ec2e897e114d282 584 Pfam PF00664 ABC transporter transmembrane region 26 285 1.1E-15 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Tharo_0960 260bb4b512474d625ec2e897e114d282 584 TIGRFAM TIGR01842 type_I_sec_PrtD: type I secretion system ATPase 19 560 6.3E-202 T 14-10-2018 IPR010128 ATPase, type I secretion system, PrtD GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 Tharo_0960 260bb4b512474d625ec2e897e114d282 584 SUPERFAMILY SSF90123 18 323 3.27E-45 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Tharo_0960 260bb4b512474d625ec2e897e114d282 584 SMART SM00382 360 546 3.0E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0960 260bb4b512474d625ec2e897e114d282 584 Gene3D G3DSA:1.20.1560.10 12 321 1.0E-40 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Tharo_0960 260bb4b512474d625ec2e897e114d282 584 Gene3D G3DSA:3.40.50.300 322 566 7.0E-70 T 14-10-2018 Tharo_0960 260bb4b512474d625ec2e897e114d282 584 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_1019 c2864fba6b58bfb987f11edb25206027 171 SUPERFAMILY SSF50341 22 163 7.32E-25 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 Tharo_1019 c2864fba6b58bfb987f11edb25206027 171 Pfam PF01584 CheW-like domain 30 163 4.2E-20 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Tharo_1019 c2864fba6b58bfb987f11edb25206027 171 Gene3D G3DSA:2.30.30.40 31 156 8.8E-19 T 14-10-2018 Tharo_1019 c2864fba6b58bfb987f11edb25206027 171 SMART SM00260 25 162 4.9E-13 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Tharo_1019 c2864fba6b58bfb987f11edb25206027 171 Gene3D G3DSA:2.40.50.180 48 157 8.8E-19 T 14-10-2018 Tharo_1411 175f82feda730caa3e015e9e1b2c6537 367 Pfam PF02817 e3 binding domain 112 147 4.4E-12 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 Tharo_1411 175f82feda730caa3e015e9e1b2c6537 367 SUPERFAMILY SSF52777 155 366 2.13E-54 T 14-10-2018 Tharo_1411 175f82feda730caa3e015e9e1b2c6537 367 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 Tharo_1411 175f82feda730caa3e015e9e1b2c6537 367 Gene3D G3DSA:2.40.50.100 3 77 2.7E-22 T 14-10-2018 Tharo_1411 175f82feda730caa3e015e9e1b2c6537 367 Gene3D G3DSA:3.30.559.10 149 366 2.7E-50 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 Tharo_1411 175f82feda730caa3e015e9e1b2c6537 367 SUPERFAMILY SSF47005 108 151 7.85E-10 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Tharo_1411 175f82feda730caa3e015e9e1b2c6537 367 SUPERFAMILY SSF51230 2 84 3.66E-24 T 14-10-2018 IPR011053 Single hybrid motif Tharo_1411 175f82feda730caa3e015e9e1b2c6537 367 Pfam PF00364 Biotin-requiring enzyme 4 73 2.2E-20 T 14-10-2018 IPR000089 Biotin/lipoyl attachment Tharo_1411 175f82feda730caa3e015e9e1b2c6537 367 Gene3D G3DSA:4.10.320.10 110 148 9.5E-13 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Tharo_1411 175f82feda730caa3e015e9e1b2c6537 367 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 160 366 3.5E-47 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 Tharo_1468 96dd4c0838e9fe7013486a8c63131f0e 579 Pfam PF07885 Ion channel 25 107 9.6E-8 T 14-10-2018 IPR013099 Potassium channel domain Tharo_1468 96dd4c0838e9fe7013486a8c63131f0e 579 SUPERFAMILY SSF81324 12 313 1.7E-15 T 14-10-2018 Tharo_1468 96dd4c0838e9fe7013486a8c63131f0e 579 Gene3D G3DSA:1.10.287.70 17 118 1.8E-8 T 14-10-2018 Tharo_1468 96dd4c0838e9fe7013486a8c63131f0e 579 Gene3D G3DSA:3.40.50.720 284 420 1.2E-26 T 14-10-2018 Tharo_1468 96dd4c0838e9fe7013486a8c63131f0e 579 SUPERFAMILY SSF51735 293 429 9.35E-28 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1468 96dd4c0838e9fe7013486a8c63131f0e 579 SUPERFAMILY SSF51735 132 278 3.94E-23 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1468 96dd4c0838e9fe7013486a8c63131f0e 579 Pfam PF02254 TrkA-N domain 133 254 1.9E-17 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Tharo_1468 96dd4c0838e9fe7013486a8c63131f0e 579 Pfam PF02254 TrkA-N domain 298 407 4.4E-19 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Tharo_1468 96dd4c0838e9fe7013486a8c63131f0e 579 Gene3D G3DSA:3.40.50.720 133 273 3.0E-25 T 14-10-2018 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 Gene3D G3DSA:2.40.50.140 13 104 7.7E-16 T 14-10-2018 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 Pfam PF00575 S1 RNA binding domain 368 441 1.5E-19 T 14-10-2018 IPR003029 S1 domain GO:0003676 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 Pfam PF00575 S1 RNA binding domain 455 527 7.9E-13 T 14-10-2018 IPR003029 S1 domain GO:0003676 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 Pfam PF00575 S1 RNA binding domain 110 178 2.0E-10 T 14-10-2018 IPR003029 S1 domain GO:0003676 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 Pfam PF00575 S1 RNA binding domain 283 354 6.5E-22 T 14-10-2018 IPR003029 S1 domain GO:0003676 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 Pfam PF00575 S1 RNA binding domain 26 92 2.8E-5 T 14-10-2018 IPR003029 S1 domain GO:0003676 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 Pfam PF00575 S1 RNA binding domain 197 267 6.0E-23 T 14-10-2018 IPR003029 S1 domain GO:0003676 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 SUPERFAMILY SSF50249 196 284 3.36E-27 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 Gene3D G3DSA:2.40.50.140 275 364 1.5E-28 T 14-10-2018 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 Gene3D G3DSA:2.40.50.140 365 451 3.9E-24 T 14-10-2018 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 Gene3D G3DSA:2.40.50.140 105 190 5.1E-8 T 14-10-2018 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 SUPERFAMILY SSF50249 354 444 1.27E-21 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 PIRSF PIRSF002111 1 541 7.1E-216 T 14-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 10 527 1.7E-207 T 14-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 SUPERFAMILY SSF50249 110 192 1.79E-14 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 SUPERFAMILY SSF50249 436 547 7.31E-22 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 Gene3D G3DSA:2.40.50.140 194 274 1.4E-28 T 14-10-2018 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 PRINTS PR00681 Ribosomal protein S1 signature 28 46 1.6E-80 T 14-10-2018 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 PRINTS PR00681 Ribosomal protein S1 signature 337 355 1.6E-80 T 14-10-2018 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 PRINTS PR00681 Ribosomal protein S1 signature 219 240 1.6E-80 T 14-10-2018 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 PRINTS PR00681 Ribosomal protein S1 signature 133 150 1.6E-80 T 14-10-2018 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 PRINTS PR00681 Ribosomal protein S1 signature 91 110 1.6E-80 T 14-10-2018 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 PRINTS PR00681 Ribosomal protein S1 signature 115 131 1.6E-80 T 14-10-2018 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 PRINTS PR00681 Ribosomal protein S1 signature 162 182 1.6E-80 T 14-10-2018 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 PRINTS PR00681 Ribosomal protein S1 signature 297 316 1.6E-80 T 14-10-2018 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 PRINTS PR00681 Ribosomal protein S1 signature 46 60 1.6E-80 T 14-10-2018 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 SUPERFAMILY SSF50249 14 119 6.79E-18 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 Gene3D G3DSA:2.40.50.140 452 534 2.8E-19 T 14-10-2018 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 SUPERFAMILY SSF50249 262 361 8.58E-27 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 SMART SM00316 456 527 8.1E-20 T 14-10-2018 IPR022967 RNA-binding domain, S1 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 SMART SM00316 369 441 5.7E-22 T 14-10-2018 IPR022967 RNA-binding domain, S1 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 SMART SM00316 197 267 3.4E-30 T 14-10-2018 IPR022967 RNA-binding domain, S1 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 SMART SM00316 110 178 3.2E-7 T 14-10-2018 IPR022967 RNA-binding domain, S1 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 SMART SM00316 26 94 0.0022 T 14-10-2018 IPR022967 RNA-binding domain, S1 Tharo_1211 539b0067712c8fb52ea2d195a692294c 567 SMART SM00316 282 354 3.4E-25 T 14-10-2018 IPR022967 RNA-binding domain, S1 Tharo_2522 2179116adb0a7fdf24175b9201d6de50 476 SUPERFAMILY SSF48452 260 447 3.17E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_2522 2179116adb0a7fdf24175b9201d6de50 476 Gene3D G3DSA:1.25.40.10 266 340 8.8E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_2522 2179116adb0a7fdf24175b9201d6de50 476 Gene3D G3DSA:3.30.2010.10 60 143 2.6E-6 T 14-10-2018 Tharo_2522 2179116adb0a7fdf24175b9201d6de50 476 Hamap MF_00997 Beta-barrel assembly-enhancing protease [bepA]. 3 473 31.795 T 14-10-2018 IPR030873 Beta-barrel assembly-enhancing protease GO:0006508|GO:0008237|GO:0016020|GO:0061077 Tharo_2522 2179116adb0a7fdf24175b9201d6de50 476 Pfam PF01435 Peptidase family M48 63 250 1.5E-34 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 Tharo_2522 2179116adb0a7fdf24175b9201d6de50 476 Gene3D G3DSA:1.25.40.10 341 469 1.9E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_2522 2179116adb0a7fdf24175b9201d6de50 476 Pfam PF14559 Tetratricopeptide repeat 342 406 2.3E-6 T 14-10-2018 Tharo_0601 d069dfcbc667309bf3a66706a2d1defa 450 SUPERFAMILY SSF102114 128 372 1.7E-57 T 14-10-2018 Tharo_0601 d069dfcbc667309bf3a66706a2d1defa 450 Pfam PF01938 TRAM domain 380 446 1.3E-15 T 14-10-2018 IPR002792 TRAM domain Tharo_0601 d069dfcbc667309bf3a66706a2d1defa 450 Gene3D G3DSA:3.80.30.20 144 380 1.5E-79 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Tharo_0601 d069dfcbc667309bf3a66706a2d1defa 450 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 3 445 2.1E-170 T 14-10-2018 Tharo_0601 d069dfcbc667309bf3a66706a2d1defa 450 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 150 170 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 Tharo_0601 d069dfcbc667309bf3a66706a2d1defa 450 Pfam PF04055 Radical SAM superfamily 150 326 6.5E-29 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_0601 d069dfcbc667309bf3a66706a2d1defa 450 SMART SM00729 146 365 5.0E-55 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Tharo_0601 d069dfcbc667309bf3a66706a2d1defa 450 Gene3D G3DSA:3.40.50.12160 2 135 1.5E-31 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily Tharo_0601 d069dfcbc667309bf3a66706a2d1defa 450 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 443 5.1E-143 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 Tharo_0601 d069dfcbc667309bf3a66706a2d1defa 450 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 2 447 72.227 T 14-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 Tharo_0601 d069dfcbc667309bf3a66706a2d1defa 450 Pfam PF00919 Uncharacterized protein family UPF0004 3 103 3.4E-28 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 Tharo_2942 217fd4c6a735722b4110fdb4b26b86ab 342 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 35 319 3.0E-51 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 Tharo_2942 217fd4c6a735722b4110fdb4b26b86ab 342 SUPERFAMILY SSF53850 132 277 1.21E-5 T 14-10-2018 Tharo_2942 217fd4c6a735722b4110fdb4b26b86ab 342 Gene3D G3DSA:3.40.190.170 28 342 6.3E-107 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily Tharo_0752 130c11065321b65738ff21e95895106f 274 Gene3D G3DSA:1.10.287.90 23 117 1.4E-25 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0752 130c11065321b65738ff21e95895106f 274 SUPERFAMILY SSF49503 118 262 2.67E-51 T 14-10-2018 IPR008972 Cupredoxin Tharo_0752 130c11065321b65738ff21e95895106f 274 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 192 240 - T 14-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0752 130c11065321b65738ff21e95895106f 274 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 121 246 2.2E-37 T 14-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0752 130c11065321b65738ff21e95895106f 274 SUPERFAMILY SSF81464 22 115 6.38E-27 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0752 130c11065321b65738ff21e95895106f 274 Gene3D G3DSA:2.60.40.420 118 260 6.6E-53 T 14-10-2018 IPR008972 Cupredoxin Tharo_0752 130c11065321b65738ff21e95895106f 274 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 29 106 1.5E-13 T 14-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0752 130c11065321b65738ff21e95895106f 274 PRINTS PR01166 Cytochrome c oxidase subunit II signature 83 95 2.9E-38 T 14-10-2018 Tharo_0752 130c11065321b65738ff21e95895106f 274 PRINTS PR01166 Cytochrome c oxidase subunit II signature 95 115 2.9E-38 T 14-10-2018 Tharo_0752 130c11065321b65738ff21e95895106f 274 PRINTS PR01166 Cytochrome c oxidase subunit II signature 211 228 2.9E-38 T 14-10-2018 Tharo_0752 130c11065321b65738ff21e95895106f 274 PRINTS PR01166 Cytochrome c oxidase subunit II signature 191 211 2.9E-38 T 14-10-2018 Tharo_0752 130c11065321b65738ff21e95895106f 274 PRINTS PR01166 Cytochrome c oxidase subunit II signature 117 136 2.9E-38 T 14-10-2018 Tharo_0752 130c11065321b65738ff21e95895106f 274 PRINTS PR01166 Cytochrome c oxidase subunit II signature 229 246 2.9E-38 T 14-10-2018 Tharo_0752 130c11065321b65738ff21e95895106f 274 PRINTS PR01166 Cytochrome c oxidase subunit II signature 167 188 2.9E-38 T 14-10-2018 Tharo_0752 130c11065321b65738ff21e95895106f 274 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 34 256 4.3E-58 T 14-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_2963 3167d718ab43f94cf9acd4a88c921eb7 333 Pfam PF02769 AIR synthase related protein, C-terminal domain 160 309 7.2E-8 T 14-10-2018 IPR010918 PurM-like, C-terminal domain Tharo_2963 3167d718ab43f94cf9acd4a88c921eb7 333 Pfam PF00586 AIR synthase related protein, N-terminal domain 39 148 2.5E-24 T 14-10-2018 IPR016188 PurM-like, N-terminal domain Tharo_2963 3167d718ab43f94cf9acd4a88c921eb7 333 PIRSF PIRSF005303 12 332 1.4E-83 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 Tharo_2963 3167d718ab43f94cf9acd4a88c921eb7 333 SUPERFAMILY SSF56042 153 313 3.14E-35 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Tharo_2963 3167d718ab43f94cf9acd4a88c921eb7 333 SUPERFAMILY SSF55326 16 148 2.79E-35 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Tharo_2963 3167d718ab43f94cf9acd4a88c921eb7 333 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 18 332 2.0E-102 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 Tharo_2963 3167d718ab43f94cf9acd4a88c921eb7 333 Gene3D G3DSA:3.90.650.10 155 332 2.3E-51 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Tharo_2963 3167d718ab43f94cf9acd4a88c921eb7 333 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 16 332 27.521 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 Tharo_2963 3167d718ab43f94cf9acd4a88c921eb7 333 Gene3D G3DSA:3.30.1330.10 15 154 4.0E-48 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Tharo_1689 1520c3d77cce2a7dc28176418848262a 391 Pfam PF00202 Aminotransferase class-III 10 381 2.4E-112 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Tharo_1689 1520c3d77cce2a7dc28176418848262a 391 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 3 387 69.08 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 Tharo_1689 1520c3d77cce2a7dc28176418848262a 391 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 4 384 9.6E-142 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 Tharo_1689 1520c3d77cce2a7dc28176418848262a 391 Gene3D G3DSA:3.40.640.10 47 295 1.2E-138 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_1689 1520c3d77cce2a7dc28176418848262a 391 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 211 248 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Tharo_1689 1520c3d77cce2a7dc28176418848262a 391 Gene3D G3DSA:3.90.1150.10 2 373 1.2E-138 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_1689 1520c3d77cce2a7dc28176418848262a 391 PIRSF PIRSF000521 1 145 6.0E-14 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Tharo_1689 1520c3d77cce2a7dc28176418848262a 391 PIRSF PIRSF000521 160 387 1.4E-33 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Tharo_1689 1520c3d77cce2a7dc28176418848262a 391 SUPERFAMILY SSF53383 3 385 2.92E-121 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_0458 c6d3d6ac01590f41e8de1799b6817f0d 136 PIRSF PIRSF004638 1 136 8.3E-51 T 14-10-2018 IPR005265 Uncharacterised protein family UPF0093 Tharo_0458 c6d3d6ac01590f41e8de1799b6817f0d 136 Pfam PF03653 Uncharacterised protein family (UPF0093) 4 136 2.3E-46 T 14-10-2018 IPR005265 Uncharacterised protein family UPF0093 Tharo_3115 9a7392f480768c2fef5674d5187b3bca 434 SMART SM00887 21 415 2.2E-79 T 14-10-2018 IPR019020 Cytochrome c-552/DMSO reductase-like, haem-binding domain GO:0020037 Tharo_3115 9a7392f480768c2fef5674d5187b3bca 434 Pfam PF09459 Ethylbenzene dehydrogenase 22 415 1.2E-64 T 14-10-2018 IPR019020 Cytochrome c-552/DMSO reductase-like, haem-binding domain GO:0020037 Tharo_0753 af198bc1ee73bb1281e2ee410ace4c89 525 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 30 471 1.0E-151 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0753 af198bc1ee73bb1281e2ee410ace4c89 525 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 249 303 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0753 af198bc1ee73bb1281e2ee410ace4c89 525 SUPERFAMILY SSF81442 18 524 2.09E-194 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0753 af198bc1ee73bb1281e2ee410ace4c89 525 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 22 523 9.7E-217 T 14-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 Tharo_0753 af198bc1ee73bb1281e2ee410ace4c89 525 PRINTS PR01165 Cytochrome c oxidase subunit I signature 138 150 2.1E-118 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0753 af198bc1ee73bb1281e2ee410ace4c89 525 PRINTS PR01165 Cytochrome c oxidase subunit I signature 21 46 2.1E-118 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0753 af198bc1ee73bb1281e2ee410ace4c89 525 PRINTS PR01165 Cytochrome c oxidase subunit I signature 196 215 2.1E-118 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0753 af198bc1ee73bb1281e2ee410ace4c89 525 PRINTS PR01165 Cytochrome c oxidase subunit I signature 167 185 2.1E-118 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0753 af198bc1ee73bb1281e2ee410ace4c89 525 PRINTS PR01165 Cytochrome c oxidase subunit I signature 68 91 2.1E-118 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0753 af198bc1ee73bb1281e2ee410ace4c89 525 PRINTS PR01165 Cytochrome c oxidase subunit I signature 352 370 2.1E-118 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0753 af198bc1ee73bb1281e2ee410ace4c89 525 PRINTS PR01165 Cytochrome c oxidase subunit I signature 95 119 2.1E-118 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0753 af198bc1ee73bb1281e2ee410ace4c89 525 PRINTS PR01165 Cytochrome c oxidase subunit I signature 317 338 2.1E-118 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0753 af198bc1ee73bb1281e2ee410ace4c89 525 PRINTS PR01165 Cytochrome c oxidase subunit I signature 293 308 2.1E-118 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0753 af198bc1ee73bb1281e2ee410ace4c89 525 PRINTS PR01165 Cytochrome c oxidase subunit I signature 380 399 2.1E-118 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0753 af198bc1ee73bb1281e2ee410ace4c89 525 PRINTS PR01165 Cytochrome c oxidase subunit I signature 247 268 2.1E-118 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0753 af198bc1ee73bb1281e2ee410ace4c89 525 PRINTS PR01165 Cytochrome c oxidase subunit I signature 430 451 2.1E-118 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0753 af198bc1ee73bb1281e2ee410ace4c89 525 Gene3D G3DSA:1.20.210.10 14 525 1.6E-218 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0911 607f91cab055e4b1a0aa20992cda6c62 165 Hamap MF_00048 UPF0102 protein YraN [yraN]. 48 160 21.311 T 14-10-2018 IPR003509 Uncharacterised protein family UPF0102 Tharo_0911 607f91cab055e4b1a0aa20992cda6c62 165 SUPERFAMILY SSF52980 50 155 1.74E-17 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Tharo_0911 607f91cab055e4b1a0aa20992cda6c62 165 Pfam PF02021 Uncharacterised protein family UPF0102 55 146 1.7E-25 T 14-10-2018 IPR003509 Uncharacterised protein family UPF0102 Tharo_0911 607f91cab055e4b1a0aa20992cda6c62 165 Gene3D G3DSA:3.40.1350.10 54 165 2.5E-29 T 14-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 Tharo_0911 607f91cab055e4b1a0aa20992cda6c62 165 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 43 162 4.7E-27 T 14-10-2018 IPR003509 Uncharacterised protein family UPF0102 Tharo_1152 55a614dafaada0955622be78f330f92e 319 SUPERFAMILY SSF55174 27 81 3.03E-6 T 14-10-2018 Tharo_1152 55a614dafaada0955622be78f330f92e 319 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 27 315 1.2E-93 T 14-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_1152 55a614dafaada0955622be78f330f92e 319 Gene3D G3DSA:3.10.290.10 17 79 1.9E-13 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Tharo_1152 55a614dafaada0955622be78f330f92e 319 Pfam PF00849 RNA pseudouridylate synthase 102 252 1.5E-34 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_1152 55a614dafaada0955622be78f330f92e 319 Gene3D G3DSA:3.30.2350.10 95 317 5.3E-74 T 14-10-2018 Tharo_1152 55a614dafaada0955622be78f330f92e 319 SUPERFAMILY SSF55120 88 315 1.1E-77 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_1152 55a614dafaada0955622be78f330f92e 319 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 145 159 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_2477 6f9aebbc3af126248395d6309f135074 339 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 50 127 2.6E-12 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 Tharo_2477 6f9aebbc3af126248395d6309f135074 339 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 48 339 52.778 T 14-10-2018 IPR023009 Tyrosine recombinase XerC/XerD Tharo_2477 6f9aebbc3af126248395d6309f135074 339 SUPERFAMILY SSF47823 48 141 1.18E-23 T 14-10-2018 Tharo_2477 6f9aebbc3af126248395d6309f135074 339 Pfam PF00589 Phage integrase family 153 324 1.1E-48 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Tharo_2477 6f9aebbc3af126248395d6309f135074 339 SUPERFAMILY SSF56349 150 336 3.53E-56 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Tharo_2477 6f9aebbc3af126248395d6309f135074 339 Gene3D G3DSA:1.10.150.130 46 139 1.9E-15 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Tharo_2477 6f9aebbc3af126248395d6309f135074 339 Gene3D G3DSA:1.10.443.10 151 333 3.0E-68 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Tharo_2477 6f9aebbc3af126248395d6309f135074 339 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 46 339 56.873 T 14-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 Tharo_2477 6f9aebbc3af126248395d6309f135074 339 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 52 338 4.7E-108 T 14-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 Tharo_2854 9ae945fca8d736262b9eb14cdb1f7822 90 SUPERFAMILY SSF47598 2 42 2.62E-10 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Tharo_2854 9ae945fca8d736262b9eb14cdb1f7822 90 Pfam PF01402 Ribbon-helix-helix protein, copG family 3 40 9.8E-7 T 14-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 Tharo_1934 55d2cc8930a06a600bd802eb9a2288be 762 Pfam PF09397 Ftsk gamma domain 696 756 2.7E-26 T 14-10-2018 IPR018541 FtsK gamma domain Tharo_1934 55d2cc8930a06a600bd802eb9a2288be 762 Gene3D G3DSA:1.10.10.10 690 755 4.3E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1934 55d2cc8930a06a600bd802eb9a2288be 762 Gene3D G3DSA:3.30.980.40 273 377 3.1E-30 T 14-10-2018 Tharo_1934 55d2cc8930a06a600bd802eb9a2288be 762 SUPERFAMILY SSF52540 371 662 3.05E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1934 55d2cc8930a06a600bd802eb9a2288be 762 Pfam PF01580 FtsK/SpoIIIE family 381 590 2.9E-67 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 Tharo_1934 55d2cc8930a06a600bd802eb9a2288be 762 SMART SM00843 694 759 1.0E-38 T 14-10-2018 IPR018541 FtsK gamma domain Tharo_1934 55d2cc8930a06a600bd802eb9a2288be 762 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 19 192 7.8E-45 T 14-10-2018 IPR025199 DNA translocase FtsK, 4TM region Tharo_1934 55d2cc8930a06a600bd802eb9a2288be 762 SUPERFAMILY SSF46785 694 759 6.35E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1934 55d2cc8930a06a600bd802eb9a2288be 762 Gene3D G3DSA:3.40.50.300 378 676 8.0E-118 T 14-10-2018 Tharo_0696 b730dae5d347f091dad28c1a6349c7cf 254 SUPERFAMILY SSF52833 34 229 1.83E-26 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_0696 b730dae5d347f091dad28c1a6349c7cf 254 Gene3D G3DSA:3.40.30.10 64 235 3.0E-32 T 14-10-2018 Tharo_0696 b730dae5d347f091dad28c1a6349c7cf 254 Pfam PF13462 Thioredoxin 65 210 4.3E-13 T 14-10-2018 IPR012336 Thioredoxin-like fold Tharo_1267 29b6619b8dd1e24ec680aeb8bb8424d7 100 Hamap MF_00460 Protein RnfH [rnfH]. 1 93 23.026 T 14-10-2018 IPR005346 RnfH protein Tharo_1267 29b6619b8dd1e24ec680aeb8bb8424d7 100 SUPERFAMILY SSF54285 1 75 2.05E-23 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp Tharo_1267 29b6619b8dd1e24ec680aeb8bb8424d7 100 Gene3D G3DSA:3.10.20.280 1 86 5.0E-27 T 14-10-2018 IPR037021 RnfH superfamily Tharo_1267 29b6619b8dd1e24ec680aeb8bb8424d7 100 Pfam PF03658 RnfH family Ubiquitin 1 81 3.1E-30 T 14-10-2018 IPR005346 RnfH protein Tharo_1191 b32dbf4207a410e472fad6ebbc7699b3 292 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 254 263 8.0E-40 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Tharo_1191 b32dbf4207a410e472fad6ebbc7699b3 292 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 132 146 8.0E-40 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Tharo_1191 b32dbf4207a410e472fad6ebbc7699b3 292 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 166 184 8.0E-40 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Tharo_1191 b32dbf4207a410e472fad6ebbc7699b3 292 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 203 220 8.0E-40 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Tharo_1191 b32dbf4207a410e472fad6ebbc7699b3 292 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 232 243 8.0E-40 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Tharo_1191 b32dbf4207a410e472fad6ebbc7699b3 292 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 2 285 7.3E-122 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Tharo_1191 b32dbf4207a410e472fad6ebbc7699b3 292 Pfam PF01039 Carboxyl transferase domain 109 243 1.6E-15 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 Tharo_1191 b32dbf4207a410e472fad6ebbc7699b3 292 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 284 37.965 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Tharo_1191 b32dbf4207a410e472fad6ebbc7699b3 292 Gene3D G3DSA:3.90.226.10 28 289 1.6E-82 T 14-10-2018 Tharo_1191 b32dbf4207a410e472fad6ebbc7699b3 292 SUPERFAMILY SSF52096 28 285 4.46E-84 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_2093 6cba07c8265035789a30a9f7c654e543 99 Pfam PF11275 Protein of unknown function (DUF3077) 17 84 1.0E-4 T 14-10-2018 IPR021427 Protein of unknown function DUF3077 Tharo_1866 4fa83f19e400f59b151ace8050bf1343 223 Pfam PF02589 LUD domain 42 220 2.6E-28 T 14-10-2018 IPR003741 LUD domain Tharo_1866 4fa83f19e400f59b151ace8050bf1343 223 SUPERFAMILY SSF100950 39 221 1.76E-40 T 14-10-2018 IPR037171 NagB/RpiA transferase-like Tharo_1866 4fa83f19e400f59b151ace8050bf1343 223 Gene3D G3DSA:3.40.50.10420 37 220 2.7E-35 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily Tharo_1310 7cc0439b70d85110ac7dd2266b034e85 155 SUPERFAMILY SSF55729 5 144 1.89E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Tharo_1310 7cc0439b70d85110ac7dd2266b034e85 155 Gene3D G3DSA:3.40.630.30 8 152 5.4E-20 T 14-10-2018 Tharo_1310 7cc0439b70d85110ac7dd2266b034e85 155 Pfam PF00583 Acetyltransferase (GNAT) family 40 138 1.6E-14 T 14-10-2018 IPR000182 GNAT domain Tharo_2830 e87bcac4d834186c6fb09f776d6b8761 464 Pfam PF05292 Malonyl-CoA decarboxylase C-terminal domain 173 435 2.3E-109 T 14-10-2018 IPR007956 Malonyl-CoA decarboxylase, C-terminal GO:0006633|GO:0050080 KEGG: 00410+4.1.1.9|KEGG: 00640+4.1.1.9|Reactome: R-HSA-390247|Reactome: R-HSA-9033241 Tharo_2830 e87bcac4d834186c6fb09f776d6b8761 464 Gene3D G3DSA:3.40.630.150 172 464 1.4E-108 T 14-10-2018 Tharo_2830 e87bcac4d834186c6fb09f776d6b8761 464 Gene3D G3DSA:1.20.140.90 27 169 3.4E-37 T 14-10-2018 IPR038351 Malonyl-CoA decarboxylase, N-terminal domain superfamily KEGG: 00410+4.1.1.9|KEGG: 00640+4.1.1.9|Reactome: R-HSA-390247|Reactome: R-HSA-9033241 Tharo_2830 e87bcac4d834186c6fb09f776d6b8761 464 Pfam PF17408 Malonyl-CoA decarboxylase N-terminal domain 83 170 1.7E-27 T 14-10-2018 IPR035372 Malonyl-CoA decarboxylase, N-terminal KEGG: 00410+4.1.1.9|KEGG: 00640+4.1.1.9|Reactome: R-HSA-390247|Reactome: R-HSA-9033241 Tharo_0839 5f186fc0f45e989caa2e8a5924e10856 467 Gene3D G3DSA:3.10.129.10 8 162 8.1E-38 T 14-10-2018 Tharo_0839 5f186fc0f45e989caa2e8a5924e10856 467 Pfam PF01575 MaoC like domain 27 118 7.8E-15 T 14-10-2018 IPR002539 MaoC-like dehydratase domain Tharo_0839 5f186fc0f45e989caa2e8a5924e10856 467 Gene3D G3DSA:3.40.718.10 169 459 3.1E-91 T 14-10-2018 Tharo_0839 5f186fc0f45e989caa2e8a5924e10856 467 SUPERFAMILY SSF53659 179 458 5.35E-64 T 14-10-2018 Tharo_0839 5f186fc0f45e989caa2e8a5924e10856 467 Pfam PF01515 Phosphate acetyl/butaryl transferase 245 449 1.2E-40 T 14-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 Tharo_0839 5f186fc0f45e989caa2e8a5924e10856 467 SUPERFAMILY SSF54637 10 148 1.3E-32 T 14-10-2018 IPR029069 HotDog domain superfamily Tharo_3114 f1af2cf73b5f3df52a38d8e486423206 102 SUPERFAMILY SSF46626 21 98 3.82E-7 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_3114 f1af2cf73b5f3df52a38d8e486423206 102 Gene3D G3DSA:1.10.760.10 14 102 5.5E-15 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_3114 f1af2cf73b5f3df52a38d8e486423206 102 Pfam PF00034 Cytochrome c 20 83 9.8E-5 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0108 5ee5e352dcb1383e429dc36596245ae5 283 Pfam PF02195 ParB-like nuclease domain 33 121 4.3E-28 T 14-10-2018 IPR003115 ParB/Sulfiredoxin Tharo_0108 5ee5e352dcb1383e429dc36596245ae5 283 SUPERFAMILY SSF109709 113 221 6.54E-33 T 14-10-2018 Tharo_0108 5ee5e352dcb1383e429dc36596245ae5 283 Gene3D G3DSA:3.90.1530.30 44 107 8.6E-28 T 14-10-2018 Tharo_0108 5ee5e352dcb1383e429dc36596245ae5 283 Gene3D G3DSA:1.10.10.2830 108 221 3.3E-35 T 14-10-2018 Tharo_0108 5ee5e352dcb1383e429dc36596245ae5 283 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 30 204 1.1E-56 T 14-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 Tharo_0108 5ee5e352dcb1383e429dc36596245ae5 283 SMART SM00470 31 121 4.3E-36 T 14-10-2018 IPR003115 ParB/Sulfiredoxin Tharo_0108 5ee5e352dcb1383e429dc36596245ae5 283 SUPERFAMILY SSF110849 33 123 1.96E-28 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily Tharo_0368 9b24ee7f54212bdb7f8ad1724da28902 567 Gene3D G3DSA:1.20.1330.10 375 517 3.1E-14 T 14-10-2018 Tharo_0368 9b24ee7f54212bdb7f8ad1724da28902 567 Pfam PF12445 Flagellin protein 335 472 5.1E-10 T 14-10-2018 IPR032826 Flagellin, H7-serospecific domain Tharo_0368 9b24ee7f54212bdb7f8ad1724da28902 567 Pfam PF00669 Bacterial flagellin N-terminal helical region 4 142 1.3E-42 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 Tharo_0368 9b24ee7f54212bdb7f8ad1724da28902 567 SUPERFAMILY SSF64518 1 567 9.94E-102 T 14-10-2018 Tharo_0368 9b24ee7f54212bdb7f8ad1724da28902 567 PRINTS PR00207 Flagellin signature 36 53 4.7E-29 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 Tharo_0368 9b24ee7f54212bdb7f8ad1724da28902 567 PRINTS PR00207 Flagellin signature 75 94 4.7E-29 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 Tharo_0368 9b24ee7f54212bdb7f8ad1724da28902 567 PRINTS PR00207 Flagellin signature 110 133 4.7E-29 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 Tharo_0368 9b24ee7f54212bdb7f8ad1724da28902 567 Gene3D G3DSA:1.20.58.1830 1 63 2.4E-7 T 14-10-2018 Tharo_0368 9b24ee7f54212bdb7f8ad1724da28902 567 Gene3D G3DSA:1.20.1330.10 64 287 2.5E-43 T 14-10-2018 Tharo_0368 9b24ee7f54212bdb7f8ad1724da28902 567 Gene3D G3DSA:1.10.8.410 518 567 1.6E-24 T 14-10-2018 Tharo_0368 9b24ee7f54212bdb7f8ad1724da28902 567 Gene3D G3DSA:3.30.70.2120 173 283 2.5E-43 T 14-10-2018 Tharo_0368 9b24ee7f54212bdb7f8ad1724da28902 567 Pfam PF00700 Bacterial flagellin C-terminal helical region 482 566 6.8E-30 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 Tharo_2965 998950317888f88056adfa72add1cbad 162 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 14 157 9.0E-49 T 14-10-2018 IPR008136 CinA, C-terminal Tharo_2965 998950317888f88056adfa72add1cbad 162 SUPERFAMILY SSF142433 5 160 2.09E-55 T 14-10-2018 IPR036653 CinA-like, C-terminal Tharo_2965 998950317888f88056adfa72add1cbad 162 Pfam PF02464 Competence-damaged protein 8 159 6.4E-59 T 14-10-2018 IPR008136 CinA, C-terminal Tharo_2965 998950317888f88056adfa72add1cbad 162 Gene3D G3DSA:3.90.950.20 1 161 9.1E-60 T 14-10-2018 IPR036653 CinA-like, C-terminal Tharo_1781 109bb6aa9dc5c1ffa8dfda65fcc09440 435 Pfam PF01842 ACT domain 354 408 8.9E-12 T 14-10-2018 IPR002912 ACT domain Tharo_1781 109bb6aa9dc5c1ffa8dfda65fcc09440 435 Gene3D G3DSA:3.30.360.10 136 348 1.5E-170 T 14-10-2018 Tharo_1781 109bb6aa9dc5c1ffa8dfda65fcc09440 435 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 1.2E-21 T 14-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 Tharo_1781 109bb6aa9dc5c1ffa8dfda65fcc09440 435 Gene3D G3DSA:3.40.50.720 4 340 1.5E-170 T 14-10-2018 Tharo_1781 109bb6aa9dc5c1ffa8dfda65fcc09440 435 SUPERFAMILY SSF51735 1 158 1.89E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1781 109bb6aa9dc5c1ffa8dfda65fcc09440 435 SUPERFAMILY SSF55021 353 423 5.66E-13 T 14-10-2018 Tharo_1781 109bb6aa9dc5c1ffa8dfda65fcc09440 435 Gene3D G3DSA:3.30.70.260 349 423 1.5E-170 T 14-10-2018 Tharo_1781 109bb6aa9dc5c1ffa8dfda65fcc09440 435 PIRSF PIRSF000098 1 435 1.4E-166 T 14-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 Tharo_1781 109bb6aa9dc5c1ffa8dfda65fcc09440 435 Pfam PF00742 Homoserine dehydrogenase 137 315 7.3E-64 T 14-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 Tharo_1781 109bb6aa9dc5c1ffa8dfda65fcc09440 435 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 14-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 Tharo_1781 109bb6aa9dc5c1ffa8dfda65fcc09440 435 SUPERFAMILY SSF55347 137 302 1.57E-52 T 14-10-2018 Tharo_2923 ad2516d774042a286d084f5e0cb9321e 267 SUPERFAMILY SSF51735 7 266 1.84E-79 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_2923 ad2516d774042a286d084f5e0cb9321e 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 6.4E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2923 ad2516d774042a286d084f5e0cb9321e 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 6.4E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2923 ad2516d774042a286d084f5e0cb9321e 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 6.4E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2923 ad2516d774042a286d084f5e0cb9321e 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 265 8.3E-67 T 14-10-2018 Tharo_2923 ad2516d774042a286d084f5e0cb9321e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.0E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2923 ad2516d774042a286d084f5e0cb9321e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 3.0E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2923 ad2516d774042a286d084f5e0cb9321e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 3.0E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2923 ad2516d774042a286d084f5e0cb9321e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 248 3.0E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2923 ad2516d774042a286d084f5e0cb9321e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 3.0E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2923 ad2516d774042a286d084f5e0cb9321e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.0E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2923 ad2516d774042a286d084f5e0cb9321e 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Tharo_2923 ad2516d774042a286d084f5e0cb9321e 267 Gene3D G3DSA:3.40.50.720 1 267 1.2E-81 T 14-10-2018 Tharo_3226 197e2bdc6218970d801a1f022470d8d8 259 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 259 51.732 T 14-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 Tharo_3226 197e2bdc6218970d801a1f022470d8d8 259 Pfam PF02654 Cobalamin-5-phosphate synthase 11 247 1.4E-51 T 14-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 Tharo_0812 1f6ba028cdbe2da4319619354487f234 77 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 1 44 2.8E-10 T 14-10-2018 Tharo_0812 1f6ba028cdbe2da4319619354487f234 77 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 57 2.9E-11 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Tharo_0812 1f6ba028cdbe2da4319619354487f234 77 SUPERFAMILY SSF143120 2 46 1.57E-8 T 14-10-2018 IPR036165 YefM-like superfamily Tharo_0812 1f6ba028cdbe2da4319619354487f234 77 Gene3D G3DSA:3.40.1620.10 1 45 8.5E-14 T 14-10-2018 Tharo_3003 fbfb5379fc3dffeb316ae4a9c973e2db 128 Pfam PF00034 Cytochrome c 39 127 2.2E-4 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_3003 fbfb5379fc3dffeb316ae4a9c973e2db 128 SUPERFAMILY SSF46626 36 126 2.22E-24 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_3003 fbfb5379fc3dffeb316ae4a9c973e2db 128 PRINTS PR00604 Class IA and IB cytochrome C signature 39 46 4.7E-15 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_3003 fbfb5379fc3dffeb316ae4a9c973e2db 128 PRINTS PR00604 Class IA and IB cytochrome C signature 68 78 4.7E-15 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_3003 fbfb5379fc3dffeb316ae4a9c973e2db 128 PRINTS PR00604 Class IA and IB cytochrome C signature 52 67 4.7E-15 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_3003 fbfb5379fc3dffeb316ae4a9c973e2db 128 PRINTS PR00604 Class IA and IB cytochrome C signature 82 98 4.7E-15 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_3003 fbfb5379fc3dffeb316ae4a9c973e2db 128 PRINTS PR00604 Class IA and IB cytochrome C signature 118 126 4.7E-15 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_3003 fbfb5379fc3dffeb316ae4a9c973e2db 128 PRINTS PR00604 Class IA and IB cytochrome C signature 101 111 4.7E-15 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_3003 fbfb5379fc3dffeb316ae4a9c973e2db 128 Gene3D G3DSA:1.10.760.10 3 127 5.6E-33 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_0572 e3eb89e9593ebe555df31a4130e8d06c 73 SUPERFAMILY SSF89447 2 46 3.14E-11 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily Tharo_0572 e3eb89e9593ebe555df31a4130e8d06c 73 Gene3D G3DSA:2.10.260.10 1 42 1.8E-11 T 14-10-2018 Tharo_0572 e3eb89e9593ebe555df31a4130e8d06c 73 Pfam PF15937 prlF antitoxin for toxin YhaV_toxin 4 51 3.6E-10 T 14-10-2018 IPR031848 PrlF antitoxin GO:0001558|GO:0003700|GO:0097351 Tharo_0572 e3eb89e9593ebe555df31a4130e8d06c 73 SMART SM00966 4 50 4.2E-11 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Tharo_0572 e3eb89e9593ebe555df31a4130e8d06c 73 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 45 5.2E-12 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Tharo_0572 e3eb89e9593ebe555df31a4130e8d06c 73 ProDom PD030562 SUPPRESSOR HTRA PROTEASE TRANSCRIPTIONAL REGULATOR HTAR SOHA ABRB YDCA BLL1688 3 52 2.0E-5 T 14-10-2018 Tharo_1953 db849ab097ef118fc37011b3a53fe2b8 164 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 5 160 35.086 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Tharo_1953 db849ab097ef118fc37011b3a53fe2b8 164 Pfam PF02542 YgbB family 5 158 3.3E-62 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Tharo_1953 db849ab097ef118fc37011b3a53fe2b8 164 SUPERFAMILY SSF69765 4 160 3.01E-63 T 14-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Tharo_1953 db849ab097ef118fc37011b3a53fe2b8 164 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 6 159 9.2E-64 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Tharo_1953 db849ab097ef118fc37011b3a53fe2b8 164 Gene3D G3DSA:3.30.1330.50 4 164 1.1E-67 T 14-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Tharo_1953 db849ab097ef118fc37011b3a53fe2b8 164 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 39 54 - T 14-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Tharo_2710 605445dea14a343a14dce7b2550b72b7 131 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 131 32.065 T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2710 605445dea14a343a14dce7b2550b72b7 131 Pfam PF00410 Ribosomal protein S8 5 130 1.2E-48 T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2710 605445dea14a343a14dce7b2550b72b7 131 Gene3D G3DSA:3.30.1490.10 74 131 1.1E-23 T 14-10-2018 Tharo_2710 605445dea14a343a14dce7b2550b72b7 131 ProSitePatterns PS00053 Ribosomal protein S8 signature. 101 118 - T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2710 605445dea14a343a14dce7b2550b72b7 131 SUPERFAMILY SSF56047 2 130 2.88E-46 T 14-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2710 605445dea14a343a14dce7b2550b72b7 131 Gene3D G3DSA:3.30.1370.30 2 73 1.7E-27 T 14-10-2018 Tharo_0776 c8d7fbee37b29e7a0421bd18e6cb0bca 297 SUPERFAMILY SSF49879 200 280 6.31E-15 T 14-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 Tharo_0776 c8d7fbee37b29e7a0421bd18e6cb0bca 297 SMART SM00240 207 256 2.0E-5 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Tharo_0776 c8d7fbee37b29e7a0421bd18e6cb0bca 297 SUPERFAMILY SSF55073 1 166 2.2E-39 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_0776 c8d7fbee37b29e7a0421bd18e6cb0bca 297 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 1 156 1.4E-11 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 Tharo_0776 c8d7fbee37b29e7a0421bd18e6cb0bca 297 Gene3D G3DSA:3.30.70.1230 1 173 6.7E-42 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_0776 c8d7fbee37b29e7a0421bd18e6cb0bca 297 Pfam PF00498 FHA domain 209 262 9.7E-9 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Tharo_0776 c8d7fbee37b29e7a0421bd18e6cb0bca 297 Gene3D G3DSA:2.60.200.20 185 285 1.2E-13 T 14-10-2018 Tharo_1930 066b9d37d55f764529cd2ce1ce9aa4d5 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.2E-42 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Tharo_1930 066b9d37d55f764529cd2ce1ce9aa4d5 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 14-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 Tharo_1930 066b9d37d55f764529cd2ce1ce9aa4d5 112 PRINTS PR00340 P-II protein signature 23 41 5.4E-45 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Tharo_1930 066b9d37d55f764529cd2ce1ce9aa4d5 112 PRINTS PR00340 P-II protein signature 52 75 5.4E-45 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Tharo_1930 066b9d37d55f764529cd2ce1ce9aa4d5 112 PRINTS PR00340 P-II protein signature 2 17 5.4E-45 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Tharo_1930 066b9d37d55f764529cd2ce1ce9aa4d5 112 PRINTS PR00340 P-II protein signature 83 103 5.4E-45 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Tharo_1930 066b9d37d55f764529cd2ce1ce9aa4d5 112 SUPERFAMILY SSF54913 1 112 6.67E-46 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta Tharo_1930 066b9d37d55f764529cd2ce1ce9aa4d5 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 14-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 Tharo_1930 066b9d37d55f764529cd2ce1ce9aa4d5 112 SMART SM00938 4 105 1.7E-67 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Tharo_1930 066b9d37d55f764529cd2ce1ce9aa4d5 112 Gene3D G3DSA:3.30.70.120 1 112 1.7E-47 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Tharo_1930 066b9d37d55f764529cd2ce1ce9aa4d5 112 PIRSF PIRSF039144 1 112 4.3E-56 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Tharo_3153 f2b4dd417ec72ec8c9d2e6773927ef69 299 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 113 280 1.8E-28 T 14-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG Tharo_3153 f2b4dd417ec72ec8c9d2e6773927ef69 299 SUPERFAMILY SSF102405 40 280 1.13E-51 T 14-10-2018 Tharo_3153 f2b4dd417ec72ec8c9d2e6773927ef69 299 Pfam PF03641 Possible lysine decarboxylase 150 278 2.1E-32 T 14-10-2018 IPR031100 LOG family Tharo_3153 f2b4dd417ec72ec8c9d2e6773927ef69 299 Gene3D G3DSA:3.40.50.450 49 284 4.9E-59 T 14-10-2018 Tharo_3060 1dd593cac584a77792f05bb3e5e6ef72 249 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 14-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 Tharo_3060 1dd593cac584a77792f05bb3e5e6ef72 249 SUPERFAMILY SSF52402 1 242 3.77E-84 T 14-10-2018 Tharo_3060 1dd593cac584a77792f05bb3e5e6ef72 249 Pfam PF01012 Electron transfer flavoprotein domain 29 206 3.8E-45 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 Tharo_3060 1dd593cac584a77792f05bb3e5e6ef72 249 Gene3D G3DSA:3.40.50.620 1 248 7.4E-88 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_3060 1dd593cac584a77792f05bb3e5e6ef72 249 SMART SM00893 23 211 8.9E-70 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 Tharo_3060 1dd593cac584a77792f05bb3e5e6ef72 249 PIRSF PIRSF000090 1 249 4.8E-85 T 14-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 Tharo_0105 ec8a49e9aeb8f45e70d6cf615159608c 644 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 624 2.6E-270 T 14-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 Tharo_0105 ec8a49e9aeb8f45e70d6cf615159608c 644 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 274 288 - T 14-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 Tharo_0105 ec8a49e9aeb8f45e70d6cf615159608c 644 SMART SM01228 548 619 1.3E-44 T 14-10-2018 Tharo_0105 ec8a49e9aeb8f45e70d6cf615159608c 644 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 369 392 - T 14-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 Tharo_0105 ec8a49e9aeb8f45e70d6cf615159608c 644 Gene3D G3DSA:1.10.10.1800 460 552 1.3E-23 T 14-10-2018 Tharo_0105 ec8a49e9aeb8f45e70d6cf615159608c 644 Pfam PF01134 Glucose inhibited division protein A 9 399 2.0E-165 T 14-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 Tharo_0105 ec8a49e9aeb8f45e70d6cf615159608c 644 Gene3D G3DSA:1.10.150.570 571 624 5.3E-25 T 14-10-2018 Tharo_0105 ec8a49e9aeb8f45e70d6cf615159608c 644 Gene3D G3DSA:3.50.50.60 296 459 7.2E-58 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_0105 ec8a49e9aeb8f45e70d6cf615159608c 644 Gene3D G3DSA:3.50.50.60 2 220 3.2E-85 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_0105 ec8a49e9aeb8f45e70d6cf615159608c 644 SUPERFAMILY SSF51905 8 262 3.04E-48 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_0105 ec8a49e9aeb8f45e70d6cf615159608c 644 Pfam PF13932 GidA associated domain 403 618 3.4E-76 T 14-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 Tharo_0105 ec8a49e9aeb8f45e70d6cf615159608c 644 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 626 42.298 T 14-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 Tharo_0658 1d7af558bf711ec14433a9120c62336e 490 Pfam PF00425 chorismate binding enzyme 218 471 3.5E-99 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal Tharo_0658 1d7af558bf711ec14433a9120c62336e 490 SUPERFAMILY SSF56322 14 482 2.62E-160 T 14-10-2018 IPR005801 ADC synthase GO:0009058 Tharo_0658 1d7af558bf711ec14433a9120c62336e 490 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 26 479 1.1E-168 T 14-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Tharo_0658 1d7af558bf711ec14433a9120c62336e 490 PRINTS PR00095 Anthranilate synthase component I signature 319 332 1.5E-22 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Tharo_0658 1d7af558bf711ec14433a9120c62336e 490 PRINTS PR00095 Anthranilate synthase component I signature 413 427 1.5E-22 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Tharo_0658 1d7af558bf711ec14433a9120c62336e 490 PRINTS PR00095 Anthranilate synthase component I signature 333 346 1.5E-22 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Tharo_0658 1d7af558bf711ec14433a9120c62336e 490 PRINTS PR00095 Anthranilate synthase component I signature 428 442 1.5E-22 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Tharo_0658 1d7af558bf711ec14433a9120c62336e 490 Gene3D G3DSA:3.60.120.10 2 487 6.6E-179 T 14-10-2018 IPR005801 ADC synthase GO:0009058 Tharo_0658 1d7af558bf711ec14433a9120c62336e 490 Pfam PF04715 Anthranilate synthase component I, N terminal region 26 169 4.0E-30 T 14-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Tharo_0243 2e3bb520e3df71eca52ae1ce82cfc90d 776 Pfam PF00067 Cytochrome P450 207 401 5.0E-15 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Tharo_0243 2e3bb520e3df71eca52ae1ce82cfc90d 776 SUPERFAMILY SSF52343 555 681 7.07E-25 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_0243 2e3bb520e3df71eca52ae1ce82cfc90d 776 SUPERFAMILY SSF63380 465 557 9.16E-17 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Tharo_0243 2e3bb520e3df71eca52ae1ce82cfc90d 776 SUPERFAMILY SSF48264 40 435 1.44E-75 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 Tharo_0243 2e3bb520e3df71eca52ae1ce82cfc90d 776 Gene3D G3DSA:3.10.20.30 681 774 4.9E-22 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Tharo_0243 2e3bb520e3df71eca52ae1ce82cfc90d 776 SUPERFAMILY SSF54292 666 774 1.31E-27 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Tharo_0243 2e3bb520e3df71eca52ae1ce82cfc90d 776 Gene3D G3DSA:2.40.30.10 459 558 1.2E-19 T 14-10-2018 Tharo_0243 2e3bb520e3df71eca52ae1ce82cfc90d 776 PRINTS PR00409 Phthalate dioxygenase reductase family signature 645 653 6.2E-27 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Tharo_0243 2e3bb520e3df71eca52ae1ce82cfc90d 776 PRINTS PR00409 Phthalate dioxygenase reductase family signature 569 588 6.2E-27 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Tharo_0243 2e3bb520e3df71eca52ae1ce82cfc90d 776 PRINTS PR00409 Phthalate dioxygenase reductase family signature 489 499 6.2E-27 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Tharo_0243 2e3bb520e3df71eca52ae1ce82cfc90d 776 PRINTS PR00409 Phthalate dioxygenase reductase family signature 533 547 6.2E-27 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Tharo_0243 2e3bb520e3df71eca52ae1ce82cfc90d 776 PRINTS PR00409 Phthalate dioxygenase reductase family signature 547 561 6.2E-27 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Tharo_0243 2e3bb520e3df71eca52ae1ce82cfc90d 776 PRINTS PR00409 Phthalate dioxygenase reductase family signature 594 603 6.2E-27 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Tharo_0243 2e3bb520e3df71eca52ae1ce82cfc90d 776 Pfam PF00175 Oxidoreductase NAD-binding domain 570 658 2.3E-5 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 Tharo_0243 2e3bb520e3df71eca52ae1ce82cfc90d 776 Gene3D G3DSA:3.40.50.80 559 675 8.5E-25 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_0243 2e3bb520e3df71eca52ae1ce82cfc90d 776 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 377 386 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Tharo_0243 2e3bb520e3df71eca52ae1ce82cfc90d 776 Gene3D G3DSA:1.10.630.10 19 446 9.4E-98 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 Tharo_0243 2e3bb520e3df71eca52ae1ce82cfc90d 776 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 696 766 2.5E-11 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Tharo_0343 8c6cf569cefff19565a2f22f4402c5de 247 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 195 216 1.1E-66 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Tharo_0343 8c6cf569cefff19565a2f22f4402c5de 247 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 66 86 1.1E-66 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Tharo_0343 8c6cf569cefff19565a2f22f4402c5de 247 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 219 244 1.1E-66 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Tharo_0343 8c6cf569cefff19565a2f22f4402c5de 247 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 86 105 1.1E-66 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Tharo_0343 8c6cf569cefff19565a2f22f4402c5de 247 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 47 66 1.1E-66 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Tharo_0343 8c6cf569cefff19565a2f22f4402c5de 247 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 174 194 1.1E-66 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Tharo_0343 8c6cf569cefff19565a2f22f4402c5de 247 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 235 245 9.9E-21 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 Tharo_0343 8c6cf569cefff19565a2f22f4402c5de 247 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 145 157 9.9E-21 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 Tharo_0343 8c6cf569cefff19565a2f22f4402c5de 247 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 105 117 9.9E-21 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 Tharo_0343 8c6cf569cefff19565a2f22f4402c5de 247 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 45 54 9.9E-21 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 Tharo_0343 8c6cf569cefff19565a2f22f4402c5de 247 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 167 179 9.9E-21 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 Tharo_0343 8c6cf569cefff19565a2f22f4402c5de 247 Pfam PF00813 FliP family 49 241 1.1E-76 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Tharo_0343 8c6cf569cefff19565a2f22f4402c5de 247 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 222 234 - T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Tharo_0343 8c6cf569cefff19565a2f22f4402c5de 247 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 49 245 2.2E-85 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 Tharo_0343 8c6cf569cefff19565a2f22f4402c5de 247 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 174 189 - T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Tharo_0869 a47f6663934a29cfa8c8dcfee5bd87b2 131 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 104 2.1E-23 T 14-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like Tharo_0195 1dcb2f0482cb33c2ae0016d848ea1104 491 Pfam PF04432 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus 191 359 1.9E-27 T 14-10-2018 IPR007525 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal Tharo_0195 1dcb2f0482cb33c2ae0016d848ea1104 491 SUPERFAMILY SSF54862 19 75 1.86E-9 T 14-10-2018 Tharo_0195 1dcb2f0482cb33c2ae0016d848ea1104 491 Gene3D G3DSA:3.30.70.20 7 83 6.1E-10 T 14-10-2018 Tharo_0195 1dcb2f0482cb33c2ae0016d848ea1104 491 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 22 33 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_0195 1dcb2f0482cb33c2ae0016d848ea1104 491 Pfam PF04422 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term 104 181 1.8E-21 T 14-10-2018 IPR007516 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal Tharo_0021 51c20f019a091b82db22dbf4109db87e 550 Pfam PF01676 Metalloenzyme superfamily 14 538 5.9E-69 T 14-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 Tharo_0021 51c20f019a091b82db22dbf4109db87e 550 Gene3D G3DSA:3.40.720.10 14 538 1.8E-180 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 Tharo_0021 51c20f019a091b82db22dbf4109db87e 550 SUPERFAMILY SSF53649 14 542 4.11E-53 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 Tharo_0021 51c20f019a091b82db22dbf4109db87e 550 PIRSF PIRSF001492 8 550 4.5E-166 T 14-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Tharo_0021 51c20f019a091b82db22dbf4109db87e 550 SUPERFAMILY SSF64158 87 327 1.15E-61 T 14-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Tharo_0021 51c20f019a091b82db22dbf4109db87e 550 Gene3D G3DSA:3.40.1450.10 87 334 1.8E-180 T 14-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Tharo_0021 51c20f019a091b82db22dbf4109db87e 550 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 93 318 1.7E-61 T 14-10-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Tharo_0021 51c20f019a091b82db22dbf4109db87e 550 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 14 538 5.9E-124 T 14-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Tharo_3276 e6f5bf4a57e2d7187f1a5618bd456bf5 167 Gene3D G3DSA:3.40.50.960 19 166 8.6E-52 T 14-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Tharo_3276 e6f5bf4a57e2d7187f1a5618bd456bf5 167 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 25 166 28.446 T 14-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Tharo_3276 e6f5bf4a57e2d7187f1a5618bd456bf5 167 SUPERFAMILY SSF52121 22 166 1.44E-52 T 14-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Tharo_3276 e6f5bf4a57e2d7187f1a5618bd456bf5 167 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 30 162 7.1E-42 T 14-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Tharo_3276 e6f5bf4a57e2d7187f1a5618bd456bf5 167 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 29 163 1.2E-49 T 14-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Tharo_0571 50a20338a8996338a6a00290f30ef104 354 Gene3D G3DSA:3.60.15.10 74 205 3.0E-11 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_0571 50a20338a8996338a6a00290f30ef104 354 SUPERFAMILY SSF56281 76 299 8.26E-19 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_0571 50a20338a8996338a6a00290f30ef104 354 SMART SM00849 79 295 0.0046 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_0571 50a20338a8996338a6a00290f30ef104 354 Pfam PF00753 Metallo-beta-lactamase superfamily 76 172 4.1E-9 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_0571 50a20338a8996338a6a00290f30ef104 354 Gene3D G3DSA:3.60.15.10 211 313 2.2E-19 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_1564 717921a911dadd776a611b594de2c3d9 425 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 329 419 5.7E-30 T 14-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Tharo_1564 717921a911dadd776a611b594de2c3d9 425 Gene3D G3DSA:3.30.470.20 189 327 1.9E-56 T 14-10-2018 Tharo_1564 717921a911dadd776a611b594de2c3d9 425 SMART SM01209 101 294 6.8E-132 T 14-10-2018 Tharo_1564 717921a911dadd776a611b594de2c3d9 425 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 294 3.6E-75 T 14-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Tharo_1564 717921a911dadd776a611b594de2c3d9 425 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 2.1E-36 T 14-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Tharo_1564 717921a911dadd776a611b594de2c3d9 425 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 421 1.8E-172 T 14-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Tharo_1564 717921a911dadd776a611b594de2c3d9 425 SUPERFAMILY SSF56059 102 321 3.54E-65 T 14-10-2018 Tharo_1564 717921a911dadd776a611b594de2c3d9 425 Gene3D G3DSA:3.30.1490.20 119 188 2.9E-25 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Tharo_1564 717921a911dadd776a611b594de2c3d9 425 SMART SM01210 328 421 8.8E-55 T 14-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Tharo_1564 717921a911dadd776a611b594de2c3d9 425 SUPERFAMILY SSF51246 327 421 6.8E-33 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 Tharo_1564 717921a911dadd776a611b594de2c3d9 425 Gene3D G3DSA:3.40.50.20 1 93 3.9E-37 T 14-10-2018 Tharo_1564 717921a911dadd776a611b594de2c3d9 425 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 421 43.622 T 14-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Tharo_1564 717921a911dadd776a611b594de2c3d9 425 SUPERFAMILY SSF52440 1 101 3.88E-35 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Tharo_1564 717921a911dadd776a611b594de2c3d9 425 Gene3D G3DSA:3.90.600.10 328 425 4.3E-35 T 14-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Tharo_1961 d9aa631e6e2ee1f713e484ad0d55f481 264 Gene3D G3DSA:3.40.50.300 11 261 1.1E-62 T 14-10-2018 Tharo_1961 d9aa631e6e2ee1f713e484ad0d55f481 264 SMART SM00382 36 226 5.6E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1961 d9aa631e6e2ee1f713e484ad0d55f481 264 Pfam PF00005 ABC transporter 29 177 1.0E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_1961 d9aa631e6e2ee1f713e484ad0d55f481 264 SUPERFAMILY SSF52540 10 237 5.75E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1013 2364551881f9e7c418c4ad2e7de4a150 560 Pfam PF12729 Four helix bundle sensory module for signal transduction 4 171 8.5E-19 T 14-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain Tharo_1013 2364551881f9e7c418c4ad2e7de4a150 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 408 437 5.8E-17 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_1013 2364551881f9e7c418c4ad2e7de4a150 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 302 331 5.8E-17 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_1013 2364551881f9e7c418c4ad2e7de4a150 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 379 406 5.8E-17 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_1013 2364551881f9e7c418c4ad2e7de4a150 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 5.8E-17 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_1013 2364551881f9e7c418c4ad2e7de4a150 560 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 326 506 5.0E-27 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_1013 2364551881f9e7c418c4ad2e7de4a150 560 Gene3D G3DSA:1.10.287.950 223 544 6.2E-47 T 14-10-2018 Tharo_1013 2364551881f9e7c418c4ad2e7de4a150 560 SUPERFAMILY SSF58104 247 543 3.05E-49 T 14-10-2018 Tharo_1013 2364551881f9e7c418c4ad2e7de4a150 560 SMART SM00283 281 542 4.9E-37 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_1687 0b8dccc105a56841d7c5abe86f17bf9e 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 5.3E-25 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_1687 0b8dccc105a56841d7c5abe86f17bf9e 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.692 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_1687 0b8dccc105a56841d7c5abe86f17bf9e 88 SUPERFAMILY SSF46992 3 86 3.92E-27 T 14-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_1687 0b8dccc105a56841d7c5abe86f17bf9e 88 Pfam PF01649 Ribosomal protein S20 2 84 1.2E-24 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_1687 0b8dccc105a56841d7c5abe86f17bf9e 88 Gene3D G3DSA:1.20.58.110 1 87 4.0E-26 T 14-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_1687 0b8dccc105a56841d7c5abe86f17bf9e 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 20 83 2.0E-25 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_0925 4daf9014e305116ef9f9dfdb1867b30a 471 Gene3D G3DSA:3.40.1190.10 94 309 1.5E-79 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Tharo_0925 4daf9014e305116ef9f9dfdb1867b30a 471 Gene3D G3DSA:3.90.190.20 310 470 2.2E-44 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Tharo_0925 4daf9014e305116ef9f9dfdb1867b30a 471 Gene3D G3DSA:3.40.50.720 6 92 1.0E-32 T 14-10-2018 Tharo_0925 4daf9014e305116ef9f9dfdb1867b30a 471 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 5 470 43.162 T 14-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Tharo_0925 4daf9014e305116ef9f9dfdb1867b30a 471 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 7 460 1.9E-165 T 14-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Tharo_0925 4daf9014e305116ef9f9dfdb1867b30a 471 Pfam PF01225 Mur ligase family, catalytic domain 8 104 4.6E-28 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 Tharo_0925 4daf9014e305116ef9f9dfdb1867b30a 471 SUPERFAMILY SSF53623 91 310 1.95E-71 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Tharo_0925 4daf9014e305116ef9f9dfdb1867b30a 471 SUPERFAMILY SSF51984 6 92 3.01E-29 T 14-10-2018 Tharo_0925 4daf9014e305116ef9f9dfdb1867b30a 471 SUPERFAMILY SSF53244 311 464 6.59E-45 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Tharo_0925 4daf9014e305116ef9f9dfdb1867b30a 471 Pfam PF08245 Mur ligase middle domain 110 292 5.5E-29 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Tharo_0925 4daf9014e305116ef9f9dfdb1867b30a 471 Pfam PF02875 Mur ligase family, glutamate ligase domain 312 408 1.8E-18 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Tharo_2217 6562c4fc8bde6df390e447a5ad7dd4ac 283 SMART SM00382 28 186 5.8E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2217 6562c4fc8bde6df390e447a5ad7dd4ac 283 SUPERFAMILY SSF52540 10 238 1.57E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2217 6562c4fc8bde6df390e447a5ad7dd4ac 283 Gene3D G3DSA:3.40.50.300 1 207 9.1E-28 T 14-10-2018 Tharo_2217 6562c4fc8bde6df390e447a5ad7dd4ac 283 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 32 179 2.0E-13 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Tharo_1849 e1f953359eb6baef83b613ef2f4ebed4 313 SUPERFAMILY SSF47823 7 96 3.92E-23 T 14-10-2018 Tharo_1849 e1f953359eb6baef83b613ef2f4ebed4 313 Gene3D G3DSA:1.10.150.130 3 95 2.7E-19 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Tharo_1849 e1f953359eb6baef83b613ef2f4ebed4 313 SUPERFAMILY SSF56349 100 302 1.94E-37 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Tharo_1849 e1f953359eb6baef83b613ef2f4ebed4 313 Pfam PF00589 Phage integrase family 131 292 2.6E-11 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Tharo_1849 e1f953359eb6baef83b613ef2f4ebed4 313 Gene3D G3DSA:1.10.443.10 99 296 2.7E-41 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Tharo_1246 4e578f5bfdaeae966039e8a99142c84f 433 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 422 5.2E-96 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit Tharo_1246 4e578f5bfdaeae966039e8a99142c84f 433 PIRSF PIRSF006066 5 433 1.2E-94 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 Tharo_1246 4e578f5bfdaeae966039e8a99142c84f 433 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 22 429 2.4E-95 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 Tharo_0478 50cdd933c5128ef48757c487e6449289 425 Gene3D G3DSA:2.30.40.10 9 421 2.7E-107 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Tharo_0478 50cdd933c5128ef48757c487e6449289 425 Pfam PF01979 Amidohydrolase family 259 421 1.5E-11 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Tharo_0478 50cdd933c5128ef48757c487e6449289 425 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 22 422 2.5E-89 T 14-10-2018 Tharo_0478 50cdd933c5128ef48757c487e6449289 425 Gene3D G3DSA:3.20.20.140 57 369 2.7E-107 T 14-10-2018 Tharo_0478 50cdd933c5128ef48757c487e6449289 425 SUPERFAMILY SSF51556 56 367 1.55E-81 T 14-10-2018 IPR032466 Metal-dependent hydrolase Tharo_0478 50cdd933c5128ef48757c487e6449289 425 SUPERFAMILY SSF51338 1 423 7.41E-29 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Tharo_1319 ed9a330e4bbb2832849b991c19bc683c 150 SUPERFAMILY SSF88723 1 137 1.26E-19 T 14-10-2018 IPR029060 PIN-like domain superfamily Tharo_1319 ed9a330e4bbb2832849b991c19bc683c 150 Pfam PF01850 PIN domain 4 118 1.1E-12 T 14-10-2018 IPR002716 PIN domain Tharo_1319 ed9a330e4bbb2832849b991c19bc683c 150 Gene3D G3DSA:3.40.50.1010 3 136 1.3E-9 T 14-10-2018 Tharo_1319 ed9a330e4bbb2832849b991c19bc683c 150 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 132 10.052 T 14-10-2018 IPR022907 VapC family GO:0004540 Tharo_2709 0ea42ce4aa3772547c884cbbda37b38e 168 SUPERFAMILY SSF56053 2 73 2.7E-18 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2709 0ea42ce4aa3772547c884cbbda37b38e 168 SUPERFAMILY SSF56053 74 168 1.83E-36 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2709 0ea42ce4aa3772547c884cbbda37b38e 168 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 167 2.1E-69 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Tharo_2709 0ea42ce4aa3772547c884cbbda37b38e 168 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 145 153 - T 14-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2709 0ea42ce4aa3772547c884cbbda37b38e 168 PIRSF PIRSF002162 1 168 6.4E-45 T 14-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2709 0ea42ce4aa3772547c884cbbda37b38e 168 Pfam PF00347 Ribosomal protein L6 2 73 7.3E-14 T 14-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2709 0ea42ce4aa3772547c884cbbda37b38e 168 Pfam PF00347 Ribosomal protein L6 81 155 1.1E-21 T 14-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2709 0ea42ce4aa3772547c884cbbda37b38e 168 Gene3D G3DSA:3.90.930.12 74 168 4.7E-40 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2709 0ea42ce4aa3772547c884cbbda37b38e 168 PRINTS PR00059 Ribosomal protein L6 signature 132 153 6.1E-34 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Tharo_2709 0ea42ce4aa3772547c884cbbda37b38e 168 PRINTS PR00059 Ribosomal protein L6 signature 90 106 6.1E-34 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Tharo_2709 0ea42ce4aa3772547c884cbbda37b38e 168 PRINTS PR00059 Ribosomal protein L6 signature 62 87 6.1E-34 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Tharo_2709 0ea42ce4aa3772547c884cbbda37b38e 168 Gene3D G3DSA:3.90.930.12 1 73 8.3E-21 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_0338 17532cc39923a719e7b6ef4b2361ef62 408 SMART SM00047 232 385 8.5E-39 T 14-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 Tharo_0338 17532cc39923a719e7b6ef4b2361ef62 408 Gene3D G3DSA:1.10.530.10 242 380 1.6E-47 T 14-10-2018 Tharo_0338 17532cc39923a719e7b6ef4b2361ef62 408 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 249 384 2.4E-21 T 14-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 Tharo_0338 17532cc39923a719e7b6ef4b2361ef62 408 Pfam PF10135 Rod binding protein 51 95 4.2E-10 T 14-10-2018 IPR019301 Flagellar protein FlgJ, N-terminal Tharo_0338 17532cc39923a719e7b6ef4b2361ef62 408 Gene3D G3DSA:2.10.70.40 276 328 1.6E-47 T 14-10-2018 Tharo_0338 17532cc39923a719e7b6ef4b2361ef62 408 PRINTS PR01002 Flagellar protein FlgJ signature 27 50 1.8E-7 T 14-10-2018 Tharo_0338 17532cc39923a719e7b6ef4b2361ef62 408 PRINTS PR01002 Flagellar protein FlgJ signature 5 25 1.8E-7 T 14-10-2018 Tharo_0338 17532cc39923a719e7b6ef4b2361ef62 408 PRINTS PR01002 Flagellar protein FlgJ signature 52 72 1.8E-7 T 14-10-2018 Tharo_0338 17532cc39923a719e7b6ef4b2361ef62 408 SUPERFAMILY SSF53955 227 279 2.06E-5 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily Tharo_0338 17532cc39923a719e7b6ef4b2361ef62 408 TIGRFAM TIGR02541 flagell_FlgJ: flagellar rod assembly protein/muramidase FlgJ 11 382 4.0E-87 T 14-10-2018 IPR013377 Peptidoglycan hydrolase FlgJ GO:0016798|GO:0044780 Tharo_1070 e463cca5da5d2b3a09ae056fd435cf79 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 123 1.6E-24 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Tharo_1070 e463cca5da5d2b3a09ae056fd435cf79 128 SUPERFAMILY SSF54593 1 128 2.95E-37 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Tharo_1070 e463cca5da5d2b3a09ae056fd435cf79 128 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 14-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 Tharo_1070 e463cca5da5d2b3a09ae056fd435cf79 128 ProSitePatterns PS00935 Glyoxalase I signature 2. 69 81 - T 14-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 Tharo_1070 e463cca5da5d2b3a09ae056fd435cf79 128 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 2 127 1.3E-64 T 14-10-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 Tharo_1070 e463cca5da5d2b3a09ae056fd435cf79 128 Gene3D G3DSA:3.10.180.10 1 128 3.5E-50 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Tharo_0483 2d47ddea5738d082a1f2e4061c668e7a 481 SUPERFAMILY SSF52425 4 170 3.27E-49 T 14-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 Tharo_0483 2d47ddea5738d082a1f2e4061c668e7a 481 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 347 366 - T 14-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal Tharo_0483 2d47ddea5738d082a1f2e4061c668e7a 481 Gene3D G3DSA:3.40.50.620 5 215 1.4E-69 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_0483 2d47ddea5738d082a1f2e4061c668e7a 481 PRINTS PR00147 DNA photolyase signature 327 343 2.2E-27 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 Tharo_0483 2d47ddea5738d082a1f2e4061c668e7a 481 PRINTS PR00147 DNA photolyase signature 347 365 2.2E-27 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 Tharo_0483 2d47ddea5738d082a1f2e4061c668e7a 481 PRINTS PR00147 DNA photolyase signature 148 164 2.2E-27 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 Tharo_0483 2d47ddea5738d082a1f2e4061c668e7a 481 PRINTS PR00147 DNA photolyase signature 386 400 2.2E-27 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 Tharo_0483 2d47ddea5738d082a1f2e4061c668e7a 481 Pfam PF03441 FAD binding domain of DNA photolyase 278 476 4.5E-84 T 14-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 Tharo_0483 2d47ddea5738d082a1f2e4061c668e7a 481 Gene3D G3DSA:1.10.579.10 296 480 1.0E-77 T 14-10-2018 Tharo_0483 2d47ddea5738d082a1f2e4061c668e7a 481 Pfam PF00875 DNA photolyase 4 168 1.2E-45 T 14-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 Tharo_0483 2d47ddea5738d082a1f2e4061c668e7a 481 SUPERFAMILY SSF48173 207 479 1.7E-103 T 14-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 Tharo_0483 2d47ddea5738d082a1f2e4061c668e7a 481 Gene3D G3DSA:1.25.40.80 137 292 1.4E-69 T 14-10-2018 Tharo_0483 2d47ddea5738d082a1f2e4061c668e7a 481 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 327 339 - T 14-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal Tharo_1143 c681ab00cc6a507c52f4c256d4318883 237 SUPERFAMILY SSF52540 4 232 8.5E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1143 c681ab00cc6a507c52f4c256d4318883 237 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_1143 c681ab00cc6a507c52f4c256d4318883 237 Gene3D G3DSA:3.40.50.300 1 237 6.4E-60 T 14-10-2018 Tharo_1143 c681ab00cc6a507c52f4c256d4318883 237 SMART SM00382 30 214 9.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1143 c681ab00cc6a507c52f4c256d4318883 237 Pfam PF00005 ABC transporter 21 165 5.4E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_3363 c681ab00cc6a507c52f4c256d4318883 237 SUPERFAMILY SSF52540 4 232 8.5E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3363 c681ab00cc6a507c52f4c256d4318883 237 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_3363 c681ab00cc6a507c52f4c256d4318883 237 Gene3D G3DSA:3.40.50.300 1 237 6.4E-60 T 14-10-2018 Tharo_3363 c681ab00cc6a507c52f4c256d4318883 237 SMART SM00382 30 214 9.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_3363 c681ab00cc6a507c52f4c256d4318883 237 Pfam PF00005 ABC transporter 21 165 5.4E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_3434 98cfeeb2df4976cc29329d488f174381 337 Gene3D G3DSA:1.10.443.10 106 318 2.2E-67 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Tharo_3434 98cfeeb2df4976cc29329d488f174381 337 SUPERFAMILY SSF56349 16 316 1.41E-50 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Tharo_3434 98cfeeb2df4976cc29329d488f174381 337 TIGRFAM TIGR02249 integrase_gron: integron integrase 16 330 1.8E-153 T 14-10-2018 IPR011946 Integrase, integron-type GO:0003677|GO:0006310|GO:0015074 Tharo_3434 98cfeeb2df4976cc29329d488f174381 337 Gene3D G3DSA:1.10.150.130 13 100 7.6E-32 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Tharo_3434 98cfeeb2df4976cc29329d488f174381 337 Pfam PF00589 Phage integrase family 116 317 4.3E-64 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Tharo_3434 98cfeeb2df4976cc29329d488f174381 337 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 17 98 2.1E-24 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 SMART SM00831 49 123 3.3E-31 T 14-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 SUPERFAMILY SSF81653 160 269 6.67E-30 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 Gene3D G3DSA:1.20.1110.10 101 932 1.3E-288 T 14-10-2018 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 SUPERFAMILY SSF81660 378 580 9.59E-51 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 Gene3D G3DSA:2.70.150.10 63 273 1.3E-288 T 14-10-2018 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 709 734 3.9E-16 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 677 693 3.9E-16 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 533 551 3.9E-16 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 649 665 3.9E-16 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 Pfam PF00690 Cation transporter/ATPase, N-terminus 51 117 7.2E-15 T 14-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 Gene3D G3DSA:3.40.1110.10 381 583 1.3E-288 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 129 269 1.8E-19 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 645 767 2.8E-34 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 271 392 7.0E-25 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 373 379 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 Pfam PF00122 E1-E2 ATPase 158 351 5.4E-52 T 14-10-2018 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 Pfam PF00702 haloacid dehalogenase-like hydrolase 368 691 3.8E-22 T 14-10-2018 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 Gene3D G3DSA:3.40.50.1000 368 722 1.3E-288 T 14-10-2018 IPR023214 HAD superfamily Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 SUPERFAMILY SSF81665 49 938 3.92E-120 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 371 385 5.1E-39 T 14-10-2018 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 208 222 5.1E-39 T 14-10-2018 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 576 587 5.1E-39 T 14-10-2018 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 677 696 5.1E-39 T 14-10-2018 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 701 713 5.1E-39 T 14-10-2018 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 598 608 5.1E-39 T 14-10-2018 Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 SUPERFAMILY SSF56784 369 782 3.12E-62 T 14-10-2018 IPR036412 HAD-like superfamily Tharo_2502 4dfbb07b16e6b99697431cc0a895c90d 947 Pfam PF00689 Cation transporting ATPase, C-terminus 762 934 6.8E-43 T 14-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 Tharo_2338 06c8982fc4067ec84e26df4c33e37ebc 147 Pfam PF08750 CNP1-like family 3 136 1.6E-44 T 14-10-2018 IPR014861 Uncharacterised domain CNP1 Tharo_3309 e4ba0d9a1cd0673f43feff3ff7cd6486 472 Pfam PF16325 Peptidase family U32 C-terminal domain 390 457 1.5E-10 T 14-10-2018 IPR032525 Peptidase family U32, C-terminal Tharo_3309 e4ba0d9a1cd0673f43feff3ff7cd6486 472 ProSitePatterns PS01276 Peptidase family U32 signature. 170 188 - T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 Tharo_3309 e4ba0d9a1cd0673f43feff3ff7cd6486 472 Pfam PF01136 Peptidase family U32 85 371 4.2E-96 T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 Tharo_3309 e4ba0d9a1cd0673f43feff3ff7cd6486 472 Gene3D G3DSA:2.40.30.10 387 446 1.3E-6 T 14-10-2018 Tharo_1521 95d53226e9e9875a0b32983326a81c4e 833 Pfam PF02687 FtsX-like permease family 290 384 1.6E-7 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Tharo_1521 95d53226e9e9875a0b32983326a81c4e 833 Pfam PF02687 FtsX-like permease family 737 824 1.1E-5 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Tharo_2987 498973e3acdbad28acc44c725b4d8623 1293 SUPERFAMILY SSF55103 407 556 1.08E-14 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 Tharo_2987 498973e3acdbad28acc44c725b4d8623 1293 Gene3D G3DSA:3.30.70.2740 672 745 2.6E-6 T 14-10-2018 Tharo_2987 498973e3acdbad28acc44c725b4d8623 1293 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 882 893 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_2987 498973e3acdbad28acc44c725b4d8623 1293 Gene3D G3DSA:1.10.1060.10 796 914 2.2E-5 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Tharo_2987 498973e3acdbad28acc44c725b4d8623 1293 SUPERFAMILY SSF55103 676 782 1.49E-26 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 Tharo_2987 498973e3acdbad28acc44c725b4d8623 1293 Pfam PF13183 4Fe-4S dicluster domain 817 896 4.3E-7 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_2987 498973e3acdbad28acc44c725b4d8623 1293 Gene3D G3DSA:3.30.465.40 124 323 6.2E-33 T 14-10-2018 Tharo_2987 498973e3acdbad28acc44c725b4d8623 1293 SUPERFAMILY SSF56176 126 397 1.59E-56 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Tharo_2987 498973e3acdbad28acc44c725b4d8623 1293 SUPERFAMILY SSF46548 800 912 3.92E-14 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Tharo_2987 498973e3acdbad28acc44c725b4d8623 1293 Pfam PF01565 FAD binding domain 165 314 2.5E-25 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Tharo_2987 498973e3acdbad28acc44c725b4d8623 1293 Pfam PF12447 Protein of unknown function (DUF3683) 3 115 3.6E-52 T 14-10-2018 IPR022153 Protein of unknown function DUF3683 Tharo_2987 498973e3acdbad28acc44c725b4d8623 1293 Pfam PF02754 Cysteine-rich domain 1034 1123 2.5E-6 T 14-10-2018 IPR004017 Cysteine-rich domain Tharo_2987 498973e3acdbad28acc44c725b4d8623 1293 Pfam PF02754 Cysteine-rich domain 1160 1244 0.02 T 14-10-2018 IPR004017 Cysteine-rich domain Tharo_2987 498973e3acdbad28acc44c725b4d8623 1293 Pfam PF11880 Domain of unknown function (DUF3400) 1248 1293 5.5E-21 T 14-10-2018 IPR021817 Protein of unknown function DUF3400 Tharo_2987 498973e3acdbad28acc44c725b4d8623 1293 Pfam PF02913 FAD linked oxidases, C-terminal domain 679 781 1.1E-17 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 Tharo_2987 498973e3acdbad28acc44c725b4d8623 1293 Pfam PF02913 FAD linked oxidases, C-terminal domain 433 550 1.0E-5 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 Tharo_0647 781e08ac48c1a6723937f1a6da9b7c0d 385 Gene3D G3DSA:2.40.10.120 55 277 9.0E-79 T 14-10-2018 Tharo_0647 781e08ac48c1a6723937f1a6da9b7c0d 385 PRINTS PR00834 HtrA/DegQ protease family signature 119 131 8.1E-55 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Tharo_0647 781e08ac48c1a6723937f1a6da9b7c0d 385 PRINTS PR00834 HtrA/DegQ protease family signature 238 255 8.1E-55 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Tharo_0647 781e08ac48c1a6723937f1a6da9b7c0d 385 PRINTS PR00834 HtrA/DegQ protease family signature 140 160 8.1E-55 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Tharo_0647 781e08ac48c1a6723937f1a6da9b7c0d 385 PRINTS PR00834 HtrA/DegQ protease family signature 216 233 8.1E-55 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Tharo_0647 781e08ac48c1a6723937f1a6da9b7c0d 385 PRINTS PR00834 HtrA/DegQ protease family signature 181 205 8.1E-55 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Tharo_0647 781e08ac48c1a6723937f1a6da9b7c0d 385 PRINTS PR00834 HtrA/DegQ protease family signature 324 336 8.1E-55 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Tharo_0647 781e08ac48c1a6723937f1a6da9b7c0d 385 Gene3D G3DSA:2.30.42.10 279 380 1.2E-24 T 14-10-2018 Tharo_0647 781e08ac48c1a6723937f1a6da9b7c0d 385 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 56 379 2.1E-128 T 14-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 Tharo_0647 781e08ac48c1a6723937f1a6da9b7c0d 385 SUPERFAMILY SSF50494 56 280 4.99E-65 T 14-10-2018 IPR009003 Peptidase S1, PA clan Tharo_0647 781e08ac48c1a6723937f1a6da9b7c0d 385 SMART SM00228 284 366 2.1E-11 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Tharo_0647 781e08ac48c1a6723937f1a6da9b7c0d 385 Pfam PF13180 PDZ domain 287 375 4.6E-11 T 14-10-2018 IPR001478 PDZ domain GO:0005515 Tharo_0647 781e08ac48c1a6723937f1a6da9b7c0d 385 SUPERFAMILY SSF50156 242 365 8.54E-24 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 Tharo_0647 781e08ac48c1a6723937f1a6da9b7c0d 385 Pfam PF13365 Trypsin-like peptidase domain 110 245 1.2E-34 T 14-10-2018 Tharo_1273 4b43b677d8e4e4b24fe4016eda59c42e 193 Hamap MF_00459 Ion-translocating oxidoreductase complex subunit A [rsxA]. 2 191 25.086 T 14-10-2018 IPR011293 Ion-translocating oxidoreductase complex, subunit RnfA/RsxA GO:0022900 Tharo_1273 4b43b677d8e4e4b24fe4016eda59c42e 193 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 3 190 1.1E-80 T 14-10-2018 IPR011293 Ion-translocating oxidoreductase complex, subunit RnfA/RsxA GO:0022900 Tharo_1273 4b43b677d8e4e4b24fe4016eda59c42e 193 Pfam PF02508 Rnf-Nqr subunit, membrane protein 5 190 7.9E-60 T 14-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 Tharo_1273 4b43b677d8e4e4b24fe4016eda59c42e 193 PIRSF PIRSF006102 1 192 5.3E-60 T 14-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 Tharo_1436 bd2a1ee3d87d17d17ad956d96ecea8c2 240 SUPERFAMILY SSF103501 1 226 2.35E-65 T 14-10-2018 IPR036197 NarG-like superfamily Tharo_1436 bd2a1ee3d87d17d17ad956d96ecea8c2 240 Pfam PF02665 Nitrate reductase gamma subunit 6 226 1.3E-80 T 14-10-2018 IPR023234 NarG-like domain Tharo_1436 bd2a1ee3d87d17d17ad956d96ecea8c2 240 Gene3D G3DSA:1.20.950.20 1 218 1.1E-75 T 14-10-2018 Tharo_1436 bd2a1ee3d87d17d17ad956d96ecea8c2 240 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 5 227 5.1E-86 T 14-10-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 Tharo_1593 37f76aff21f41cdee9894596e8a82bbd 1021 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 423 9.3E-159 T 14-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 Tharo_1593 37f76aff21f41cdee9894596e8a82bbd 1021 Hamap MF_00970 Ribonuclease E [rne]. 1 969 33.761 T 14-10-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 Tharo_1593 37f76aff21f41cdee9894596e8a82bbd 1021 Gene3D G3DSA:3.40.1260.20 399 510 1.3E-36 T 14-10-2018 Tharo_1593 37f76aff21f41cdee9894596e8a82bbd 1021 SUPERFAMILY SSF50249 40 124 2.4E-17 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_1593 37f76aff21f41cdee9894596e8a82bbd 1021 Pfam PF10150 Ribonuclease E/G family 120 389 3.8E-92 T 14-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 Tharo_1593 37f76aff21f41cdee9894596e8a82bbd 1021 Gene3D G3DSA:2.40.50.140 31 124 2.0E-30 T 14-10-2018 Tharo_1593 37f76aff21f41cdee9894596e8a82bbd 1021 Pfam PF00575 S1 RNA binding domain 38 117 4.5E-10 T 14-10-2018 IPR003029 S1 domain GO:0003676 Tharo_1593 37f76aff21f41cdee9894596e8a82bbd 1021 SMART SM00316 37 118 2.4E-9 T 14-10-2018 IPR022967 RNA-binding domain, S1 Tharo_3444 dcd95de7dc734b1043bebe1b1cd0fda4 375 Pfam PF07690 Major Facilitator Superfamily 2 200 3.8E-29 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_3444 dcd95de7dc734b1043bebe1b1cd0fda4 375 ProSitePatterns PS00216 Sugar transport proteins signature 1. 39 55 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Tharo_3444 dcd95de7dc734b1043bebe1b1cd0fda4 375 PRINTS PR01035 Tetracycline resistance protein signature 137 157 7.7E-145 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Tharo_3444 dcd95de7dc734b1043bebe1b1cd0fda4 375 PRINTS PR01035 Tetracycline resistance protein signature 195 212 7.7E-145 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Tharo_3444 dcd95de7dc734b1043bebe1b1cd0fda4 375 PRINTS PR01035 Tetracycline resistance protein signature 21 40 7.7E-145 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Tharo_3444 dcd95de7dc734b1043bebe1b1cd0fda4 375 PRINTS PR01035 Tetracycline resistance protein signature 342 361 7.7E-145 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Tharo_3444 dcd95de7dc734b1043bebe1b1cd0fda4 375 PRINTS PR01035 Tetracycline resistance protein signature 109 131 7.7E-145 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Tharo_3444 dcd95de7dc734b1043bebe1b1cd0fda4 375 PRINTS PR01035 Tetracycline resistance protein signature 277 297 7.7E-145 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Tharo_3444 dcd95de7dc734b1043bebe1b1cd0fda4 375 PRINTS PR01035 Tetracycline resistance protein signature 52 76 7.7E-145 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Tharo_3444 dcd95de7dc734b1043bebe1b1cd0fda4 375 PRINTS PR01035 Tetracycline resistance protein signature 224 244 7.7E-145 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Tharo_3444 dcd95de7dc734b1043bebe1b1cd0fda4 375 PRINTS PR01035 Tetracycline resistance protein signature 252 273 7.7E-145 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Tharo_3444 dcd95de7dc734b1043bebe1b1cd0fda4 375 PRINTS PR01035 Tetracycline resistance protein signature 79 100 7.7E-145 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Tharo_3444 dcd95de7dc734b1043bebe1b1cd0fda4 375 PRINTS PR01035 Tetracycline resistance protein signature 312 335 7.7E-145 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Tharo_3444 dcd95de7dc734b1043bebe1b1cd0fda4 375 Gene3D G3DSA:1.20.1250.20 1 361 2.0E-63 T 14-10-2018 Tharo_3444 dcd95de7dc734b1043bebe1b1cd0fda4 375 SUPERFAMILY SSF103473 2 363 2.22E-58 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_3444 dcd95de7dc734b1043bebe1b1cd0fda4 375 TIGRFAM TIGR00880 2_A_01_02: multidrug resistance protein 22 159 7.1E-39 T 14-10-2018 IPR004734 Multidrug resistance protein GO:0015238|GO:0015893|GO:0016021 Reactome: R-HSA-442660 Tharo_2776 e75357827e92568f23dd0911ff5a14e0 223 Gene3D G3DSA:3.10.580.10 1 132 3.4E-29 T 14-10-2018 Tharo_2776 e75357827e92568f23dd0911ff5a14e0 223 SMART SM00116 10 57 5.1E-8 T 14-10-2018 IPR000644 CBS domain Tharo_2776 e75357827e92568f23dd0911ff5a14e0 223 SMART SM00116 84 131 4.9E-5 T 14-10-2018 IPR000644 CBS domain Tharo_2776 e75357827e92568f23dd0911ff5a14e0 223 SUPERFAMILY SSF54631 1 128 1.25E-27 T 14-10-2018 Tharo_2776 e75357827e92568f23dd0911ff5a14e0 223 Pfam PF00571 CBS domain 77 123 1.8E-8 T 14-10-2018 IPR000644 CBS domain Tharo_2776 e75357827e92568f23dd0911ff5a14e0 223 Pfam PF00571 CBS domain 3 55 9.5E-11 T 14-10-2018 IPR000644 CBS domain Tharo_0998 cb67a00d7ee45a28a7e4a8df588e073b 431 SMART SM00244 106 279 9.0E-23 T 14-10-2018 IPR001107 Band 7 domain Tharo_0998 cb67a00d7ee45a28a7e4a8df588e073b 431 Gene3D G3DSA:3.30.479.30 162 270 7.1E-19 T 14-10-2018 Tharo_0998 cb67a00d7ee45a28a7e4a8df588e073b 431 Pfam PF12221 Bacterial membrane protein N terminal 1 65 2.9E-10 T 14-10-2018 IPR020980 Menbrane protein HflK, N-terminal Tharo_0998 cb67a00d7ee45a28a7e4a8df588e073b 431 Pfam PF01145 SPFH domain / Band 7 family 110 294 1.0E-23 T 14-10-2018 IPR001107 Band 7 domain Tharo_0998 cb67a00d7ee45a28a7e4a8df588e073b 431 TIGRFAM TIGR01933 hflK: HflK protein 108 381 8.7E-94 T 14-10-2018 IPR010201 HflK GO:0016021 Tharo_0998 cb67a00d7ee45a28a7e4a8df588e073b 431 SUPERFAMILY SSF117892 173 286 1.31E-18 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily Tharo_1005 b0972b9e80d76a11c8761491db929033 1034 SUPERFAMILY SSF50249 301 710 1.6E-141 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_1005 b0972b9e80d76a11c8761491db929033 1034 TIGRFAM TIGR02063 RNase_R: ribonuclease R 101 794 1.1E-261 T 14-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 Tharo_1005 b0972b9e80d76a11c8761491db929033 1034 Pfam PF08206 Ribonuclease B OB domain 168 225 6.1E-23 T 14-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain Tharo_1005 b0972b9e80d76a11c8761491db929033 1034 SMART SM00316 161 223 61.0 T 14-10-2018 IPR022967 RNA-binding domain, S1 Tharo_1005 b0972b9e80d76a11c8761491db929033 1034 SMART SM00316 710 793 6.6E-14 T 14-10-2018 IPR022967 RNA-binding domain, S1 Tharo_1005 b0972b9e80d76a11c8761491db929033 1034 ProSitePatterns PS01175 Ribonuclease II family signature. 636 660 - T 14-10-2018 IPR022966 Ribonuclease II/R, conserved site Tharo_1005 b0972b9e80d76a11c8761491db929033 1034 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 150 793 2.9E-224 T 14-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 Tharo_1005 b0972b9e80d76a11c8761491db929033 1034 SMART SM00357 167 226 3.1E-15 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 Tharo_1005 b0972b9e80d76a11c8761491db929033 1034 Gene3D G3DSA:2.40.50.140 157 229 1.7E-19 T 14-10-2018 Tharo_1005 b0972b9e80d76a11c8761491db929033 1034 SUPERFAMILY SSF50249 219 318 8.57E-20 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_1005 b0972b9e80d76a11c8761491db929033 1034 Gene3D G3DSA:2.40.50.140 713 819 1.5E-21 T 14-10-2018 Tharo_1005 b0972b9e80d76a11c8761491db929033 1034 SMART SM00955 341 669 1.0E-181 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 Tharo_1005 b0972b9e80d76a11c8761491db929033 1034 SUPERFAMILY SSF50249 710 790 8.58E-19 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_1005 b0972b9e80d76a11c8761491db929033 1034 Pfam PF00773 RNB domain 341 667 1.8E-104 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 Tharo_1005 b0972b9e80d76a11c8761491db929033 1034 Pfam PF00575 S1 RNA binding domain 709 790 1.9E-11 T 14-10-2018 IPR003029 S1 domain GO:0003676 Tharo_1005 b0972b9e80d76a11c8761491db929033 1034 Hamap MF_01895 Ribonuclease R [rnr]. 119 793 57.233 T 14-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 Tharo_1005 b0972b9e80d76a11c8761491db929033 1034 SUPERFAMILY SSF50249 148 228 1.06E-20 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_1226 4321db93890604531205b7a44eac069e 343 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 8 342 47.139 T 14-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 Tharo_1226 4321db93890604531205b7a44eac069e 343 SUPERFAMILY SSF55681 92 343 1.46E-76 T 14-10-2018 Tharo_1226 4321db93890604531205b7a44eac069e 343 SUPERFAMILY SSF46589 14 99 6.8E-18 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 Tharo_1226 4321db93890604531205b7a44eac069e 343 Pfam PF01409 tRNA synthetases class II core domain (F) 92 342 1.4E-96 T 14-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 Tharo_1226 4321db93890604531205b7a44eac069e 343 Gene3D G3DSA:3.30.930.10 7 343 5.8E-114 T 14-10-2018 Tharo_1226 4321db93890604531205b7a44eac069e 343 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 87 3.9E-19 T 14-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 Tharo_1226 4321db93890604531205b7a44eac069e 343 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 39 342 3.8E-96 T 14-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 Tharo_2662 52751ada566975bc6180d6990abb9717 212 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 18 207 1.9E-106 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Tharo_2662 52751ada566975bc6180d6990abb9717 212 PRINTS PR00127 Clp protease catalytic subunit P signature 75 95 2.4E-53 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Tharo_2662 52751ada566975bc6180d6990abb9717 212 PRINTS PR00127 Clp protease catalytic subunit P signature 35 50 2.4E-53 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Tharo_2662 52751ada566975bc6180d6990abb9717 212 PRINTS PR00127 Clp protease catalytic subunit P signature 106 123 2.4E-53 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Tharo_2662 52751ada566975bc6180d6990abb9717 212 PRINTS PR00127 Clp protease catalytic subunit P signature 184 203 2.4E-53 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Tharo_2662 52751ada566975bc6180d6990abb9717 212 PRINTS PR00127 Clp protease catalytic subunit P signature 127 146 2.4E-53 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Tharo_2662 52751ada566975bc6180d6990abb9717 212 SUPERFAMILY SSF52096 27 210 3.12E-76 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_2662 52751ada566975bc6180d6990abb9717 212 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 19 209 44.743 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Tharo_2662 52751ada566975bc6180d6990abb9717 212 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 128 141 - T 14-10-2018 IPR033135 ClpP, histidine active site Tharo_2662 52751ada566975bc6180d6990abb9717 212 Pfam PF00574 Clp protease 29 208 2.2E-89 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA Tharo_2662 52751ada566975bc6180d6990abb9717 212 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 106 117 - T 14-10-2018 IPR018215 ClpP, Ser active site Tharo_2662 52751ada566975bc6180d6990abb9717 212 Gene3D G3DSA:3.90.226.10 8 211 7.5E-85 T 14-10-2018 Tharo_1795 12ea4c405ef6180582c688611b3b2f07 349 Gene3D G3DSA:3.40.250.10 5 131 5.7E-38 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Tharo_1795 12ea4c405ef6180582c688611b3b2f07 349 ProSitePatterns PS00380 Rhodanese signature 1. 26 37 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 Tharo_1795 12ea4c405ef6180582c688611b3b2f07 349 Pfam PF00581 Rhodanese-like domain 12 125 6.0E-9 T 14-10-2018 IPR001763 Rhodanese-like domain Tharo_1795 12ea4c405ef6180582c688611b3b2f07 349 SUPERFAMILY SSF52821 17 130 6.16E-23 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Tharo_1795 12ea4c405ef6180582c688611b3b2f07 349 TIGRFAM TIGR03167 tRNA_sel_U_synt: tRNA 2-selenouridine synthase 14 315 6.7E-109 T 14-10-2018 IPR017582 tRNA 2-selenouridine/geranyl-2-thiouridine synthase GO:0016785|GO:0043828|GO:0070329 Tharo_1795 12ea4c405ef6180582c688611b3b2f07 349 SMART SM00450 3 130 2.0E-10 T 14-10-2018 IPR001763 Rhodanese-like domain Tharo_0636 d992aef96967fe9b4f1b9036b700dd92 394 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 248 257 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 Tharo_0636 d992aef96967fe9b4f1b9036b700dd92 394 Gene3D G3DSA:3.40.640.10 75 300 6.6E-107 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_0636 d992aef96967fe9b4f1b9036b700dd92 394 SUPERFAMILY SSF53383 42 392 1.07E-77 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_0636 d992aef96967fe9b4f1b9036b700dd92 394 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 46 391 6.6E-89 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 Tharo_0636 d992aef96967fe9b4f1b9036b700dd92 394 Pfam PF00155 Aminotransferase class I and II 62 388 4.1E-59 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Tharo_0636 d992aef96967fe9b4f1b9036b700dd92 394 Gene3D G3DSA:3.90.1150.10 57 380 6.6E-107 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_0636 d992aef96967fe9b4f1b9036b700dd92 394 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 41 392 54.866 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 Tharo_2064 4ab8575104ece5d62291e37d2c814f13 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.824 T 14-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 Tharo_2064 4ab8575104ece5d62291e37d2c814f13 185 Gene3D G3DSA:1.10.132.20 12 182 9.4E-66 T 14-10-2018 Tharo_2064 4ab8575104ece5d62291e37d2c814f13 185 Gene3D G3DSA:3.30.1360.40 31 105 9.4E-66 T 14-10-2018 Tharo_2064 4ab8575104ece5d62291e37d2c814f13 185 SUPERFAMILY SSF55194 1 185 1.24E-70 T 14-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 Tharo_2064 4ab8575104ece5d62291e37d2c814f13 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 2.4E-67 T 14-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 Tharo_2064 4ab8575104ece5d62291e37d2c814f13 185 Pfam PF01765 Ribosome recycling factor 20 183 1.5E-61 T 14-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 Tharo_2819 1d12c8507859b4ae800dc92d05eabb56 266 Pfam PF00072 Response regulator receiver domain 11 120 2.1E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2819 1d12c8507859b4ae800dc92d05eabb56 266 SUPERFAMILY SSF52172 10 169 8.15E-36 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_2819 1d12c8507859b4ae800dc92d05eabb56 266 SMART SM00448 9 119 1.3E-36 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2819 1d12c8507859b4ae800dc92d05eabb56 266 Gene3D G3DSA:1.10.10.10 128 231 2.4E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2819 1d12c8507859b4ae800dc92d05eabb56 266 SUPERFAMILY SSF46894 137 231 1.53E-24 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_2819 1d12c8507859b4ae800dc92d05eabb56 266 Gene3D G3DSA:3.40.50.2300 3 127 6.6E-31 T 14-10-2018 Tharo_2819 1d12c8507859b4ae800dc92d05eabb56 266 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 230 1.6E-19 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_2819 1d12c8507859b4ae800dc92d05eabb56 266 SMART SM00862 154 230 6.2E-19 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_2918 56b037f4c698a3f9931ae20f7e960211 164 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 106 120 7.1E-11 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 Tharo_2918 56b037f4c698a3f9931ae20f7e960211 164 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 121 134 7.1E-11 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 Tharo_2918 56b037f4c698a3f9931ae20f7e960211 164 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 89 102 7.1E-11 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 Tharo_2918 56b037f4c698a3f9931ae20f7e960211 164 SUPERFAMILY SSF51230 84 160 6.02E-18 T 14-10-2018 IPR011053 Single hybrid motif Tharo_2918 56b037f4c698a3f9931ae20f7e960211 164 Gene3D G3DSA:2.40.50.100 83 160 5.3E-21 T 14-10-2018 Tharo_2918 56b037f4c698a3f9931ae20f7e960211 164 Pfam PF00364 Biotin-requiring enzyme 86 159 6.1E-15 T 14-10-2018 IPR000089 Biotin/lipoyl attachment Tharo_3267 7367bf3634d75709c50178f0508ee9ff 341 Pfam PF00953 Glycosyl transferase family 4 78 230 5.4E-32 T 14-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 Tharo_1738 de93b630ad1c36ebe9295e92dfa1d606 487 SMART SM00116 95 142 2.7E-9 T 14-10-2018 IPR000644 CBS domain Tharo_1738 de93b630ad1c36ebe9295e92dfa1d606 487 SMART SM00116 156 204 1.7E-4 T 14-10-2018 IPR000644 CBS domain Tharo_1738 de93b630ad1c36ebe9295e92dfa1d606 487 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 293 305 - T 14-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 Tharo_1738 de93b630ad1c36ebe9295e92dfa1d606 487 SUPERFAMILY SSF54631 94 202 1.46E-27 T 14-10-2018 Tharo_1738 de93b630ad1c36ebe9295e92dfa1d606 487 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 7 473 8.9E-162 T 14-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 Tharo_1738 de93b630ad1c36ebe9295e92dfa1d606 487 Pfam PF00571 CBS domain 94 136 9.8E-9 T 14-10-2018 IPR000644 CBS domain Tharo_1738 de93b630ad1c36ebe9295e92dfa1d606 487 Pfam PF00571 CBS domain 147 202 1.2E-8 T 14-10-2018 IPR000644 CBS domain Tharo_1738 de93b630ad1c36ebe9295e92dfa1d606 487 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 7 486 84.818 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 Tharo_1738 de93b630ad1c36ebe9295e92dfa1d606 487 PIRSF PIRSF000130 1 487 3.7E-202 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 Tharo_1738 de93b630ad1c36ebe9295e92dfa1d606 487 SUPERFAMILY SSF51412 2 477 1.01E-122 T 14-10-2018 Tharo_1738 de93b630ad1c36ebe9295e92dfa1d606 487 Gene3D G3DSA:3.20.20.70 1 486 1.4E-211 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_1738 de93b630ad1c36ebe9295e92dfa1d606 487 SMART SM01240 6 473 0.0 T 14-10-2018 Tharo_1738 de93b630ad1c36ebe9295e92dfa1d606 487 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 7 454 2.2E-191 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 Tharo_0687 7f3dd234482140eaed4c63fbb300fd35 105 SMART SM00966 8 53 1.2E-9 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Tharo_0687 7f3dd234482140eaed4c63fbb300fd35 105 SUPERFAMILY SSF89447 3 49 9.59E-11 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily Tharo_0687 7f3dd234482140eaed4c63fbb300fd35 105 Pfam PF15937 prlF antitoxin for toxin YhaV_toxin 8 102 3.4E-17 T 14-10-2018 IPR031848 PrlF antitoxin GO:0001558|GO:0003700|GO:0097351 Tharo_0687 7f3dd234482140eaed4c63fbb300fd35 105 ProDom PD030562 SUPPRESSOR HTRA PROTEASE TRANSCRIPTIONAL REGULATOR HTAR SOHA ABRB YDCA BLL1688 8 70 4.0E-8 T 14-10-2018 Tharo_0687 7f3dd234482140eaed4c63fbb300fd35 105 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 9 48 1.8E-9 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Tharo_0687 7f3dd234482140eaed4c63fbb300fd35 105 Gene3D G3DSA:2.10.260.10 2 46 1.1E-12 T 14-10-2018 Tharo_1818 6ef074cacb047081f285cdab90db542b 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 66 2.0E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1818 6ef074cacb047081f285cdab90db542b 296 Pfam PF03466 LysR substrate binding domain 92 293 6.7E-34 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_1818 6ef074cacb047081f285cdab90db542b 296 Gene3D G3DSA:1.10.10.10 7 91 2.1E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1818 6ef074cacb047081f285cdab90db542b 296 SUPERFAMILY SSF53850 96 295 2.17E-35 T 14-10-2018 Tharo_1818 6ef074cacb047081f285cdab90db542b 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.2E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1818 6ef074cacb047081f285cdab90db542b 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.2E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1818 6ef074cacb047081f285cdab90db542b 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.2E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1818 6ef074cacb047081f285cdab90db542b 296 Gene3D G3DSA:3.40.190.10 104 289 1.6E-56 T 14-10-2018 Tharo_1818 6ef074cacb047081f285cdab90db542b 296 SUPERFAMILY SSF46785 5 82 3.6E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1818 6ef074cacb047081f285cdab90db542b 296 Gene3D G3DSA:3.40.190.10 164 262 1.6E-56 T 14-10-2018 Tharo_2539 b57ec8a5aafdcb9eaea076281beb2234 196 SUPERFAMILY SSF52507 2 186 2.62E-61 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 Tharo_2539 b57ec8a5aafdcb9eaea076281beb2234 196 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 3 184 4.4E-70 T 14-10-2018 IPR004507 Flavin prenyltransferase UbiX-like Tharo_2539 b57ec8a5aafdcb9eaea076281beb2234 196 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 2 186 36.951 T 14-10-2018 IPR004507 Flavin prenyltransferase UbiX-like Tharo_2539 b57ec8a5aafdcb9eaea076281beb2234 196 Gene3D G3DSA:3.40.50.1950 2 191 7.3E-79 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 Tharo_2539 b57ec8a5aafdcb9eaea076281beb2234 196 Pfam PF02441 Flavoprotein 2 165 2.1E-23 T 14-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 Tharo_2661 768033789a935f25c80e5d9b23cd8809 422 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 414 53.394 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 Tharo_2661 768033789a935f25c80e5d9b23cd8809 422 Gene3D G3DSA:3.30.50.30 2 51 8.2E-25 T 14-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily Tharo_2661 768033789a935f25c80e5d9b23cd8809 422 SMART SM00994 11 50 4.1E-24 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 Tharo_2661 768033789a935f25c80e5d9b23cd8809 422 Gene3D G3DSA:1.10.8.60 315 421 1.2E-39 T 14-10-2018 Tharo_2661 768033789a935f25c80e5d9b23cd8809 422 SMART SM00382 112 332 7.9E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2661 768033789a935f25c80e5d9b23cd8809 422 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 316 389 2.0E-14 T 14-10-2018 IPR019489 Clp ATPase, C-terminal Tharo_2661 768033789a935f25c80e5d9b23cd8809 422 SUPERFAMILY SSF57716 12 47 8.98E-12 T 14-10-2018 Tharo_2661 768033789a935f25c80e5d9b23cd8809 422 Pfam PF06689 ClpX C4-type zinc finger 12 48 3.7E-20 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 Tharo_2661 768033789a935f25c80e5d9b23cd8809 422 Gene3D G3DSA:3.40.50.300 58 314 1.2E-108 T 14-10-2018 Tharo_2661 768033789a935f25c80e5d9b23cd8809 422 SMART SM01086 316 410 2.4E-33 T 14-10-2018 IPR019489 Clp ATPase, C-terminal Tharo_2661 768033789a935f25c80e5d9b23cd8809 422 Pfam PF07724 AAA domain (Cdc48 subfamily) 113 309 1.9E-49 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Tharo_2661 768033789a935f25c80e5d9b23cd8809 422 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 411 3.8E-204 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 Tharo_2661 768033789a935f25c80e5d9b23cd8809 422 SUPERFAMILY SSF52540 63 403 5.4E-76 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2548 20fa96d2ad5e1d3e950ecec75f6833bf 289 Gene3D G3DSA:3.30.465.10 4 179 5.7E-56 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Tharo_2548 20fa96d2ad5e1d3e950ecec75f6833bf 289 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 6 177 7.8E-51 T 14-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 Tharo_2548 20fa96d2ad5e1d3e950ecec75f6833bf 289 SUPERFAMILY SSF56176 6 177 6.54E-50 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Tharo_2548 20fa96d2ad5e1d3e950ecec75f6833bf 289 Gene3D G3DSA:3.30.390.50 183 288 2.1E-31 T 14-10-2018 Tharo_2548 20fa96d2ad5e1d3e950ecec75f6833bf 289 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 186 285 8.1E-24 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal Tharo_2548 20fa96d2ad5e1d3e950ecec75f6833bf 289 SMART SM01092 184 286 2.2E-29 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal Tharo_2548 20fa96d2ad5e1d3e950ecec75f6833bf 289 SUPERFAMILY SSF55447 184 288 4.45E-30 T 14-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily Tharo_2086 27b2afec8f47fbb5ae594dd9b2b9ec93 127 Pfam PF01592 NifU-like N terminal domain 2 125 8.8E-56 T 14-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 Tharo_2086 27b2afec8f47fbb5ae594dd9b2b9ec93 127 Gene3D G3DSA:3.90.1010.10 1 127 5.2E-57 T 14-10-2018 Tharo_2086 27b2afec8f47fbb5ae594dd9b2b9ec93 127 SUPERFAMILY SSF82649 1 125 1.47E-48 T 14-10-2018 Tharo_2086 27b2afec8f47fbb5ae594dd9b2b9ec93 127 TIGRFAM TIGR01999 iscU: FeS cluster assembly scaffold IscU 3 125 5.6E-68 T 14-10-2018 IPR011339 ISC system FeS cluster assembly, IscU scaffold GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 Tharo_2334 cfe90b3ab4776c47abf950cc4e12fa76 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 1.7E-45 T 14-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 Tharo_2334 cfe90b3ab4776c47abf950cc4e12fa76 130 SUPERFAMILY SSF54211 5 130 4.55E-47 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_2334 cfe90b3ab4776c47abf950cc4e12fa76 130 Gene3D G3DSA:3.30.230.10 1 130 3.4E-51 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Tharo_2334 cfe90b3ab4776c47abf950cc4e12fa76 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 14-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 Tharo_2334 cfe90b3ab4776c47abf950cc4e12fa76 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 32.463 T 14-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid Tharo_0656 1cfaa68c062b307573808bb2b5d6cd86 231 PIRSF PIRSF001461 1 231 8.7E-97 T 14-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 Tharo_0656 1cfaa68c062b307573808bb2b5d6cd86 231 Pfam PF00834 Ribulose-phosphate 3 epimerase family 4 204 2.3E-88 T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 Tharo_0656 1cfaa68c062b307573808bb2b5d6cd86 231 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 Tharo_0656 1cfaa68c062b307573808bb2b5d6cd86 231 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 4 207 3.6E-91 T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 Tharo_0656 1cfaa68c062b307573808bb2b5d6cd86 231 SUPERFAMILY SSF51366 1 207 2.89E-69 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Tharo_0656 1cfaa68c062b307573808bb2b5d6cd86 231 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 Tharo_0656 1cfaa68c062b307573808bb2b5d6cd86 231 Gene3D G3DSA:3.20.20.70 1 218 5.1E-77 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_0771 9df6c63c2f4f90edf3c7fcec971cb92d 680 Pfam PF09423 PhoD-like phosphatase 347 615 7.5E-7 T 14-10-2018 IPR018946 Alkaline phosphatase D-related Tharo_0771 9df6c63c2f4f90edf3c7fcec971cb92d 680 SUPERFAMILY SSF56300 199 585 1.14E-8 T 14-10-2018 Tharo_0771 9df6c63c2f4f90edf3c7fcec971cb92d 680 Gene3D G3DSA:3.60.21.70 341 585 1.1E-7 T 14-10-2018 IPR038607 PhoD-like superfamily Tharo_0403 611ffc3dd49601db1ed641d0e29050d7 223 Gene3D G3DSA:1.10.287.500 38 171 2.6E-52 T 14-10-2018 Tharo_0403 611ffc3dd49601db1ed641d0e29050d7 223 Gene3D G3DSA:1.20.5.590 12 37 2.6E-7 T 14-10-2018 Tharo_0403 611ffc3dd49601db1ed641d0e29050d7 223 PIRSF PIRSF002884 2 223 1.0E-80 T 14-10-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 Tharo_0403 611ffc3dd49601db1ed641d0e29050d7 223 Pfam PF04344 Chemotaxis phosphatase, CheZ 19 223 2.8E-78 T 14-10-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 Tharo_0403 611ffc3dd49601db1ed641d0e29050d7 223 SUPERFAMILY SSF75708 18 222 3.01E-63 T 14-10-2018 Tharo_1415 e02955222263cf1d9eee70b8c2af6813 571 SUPERFAMILY SSF64182 52 467 5.49E-115 T 14-10-2018 IPR038763 DHH phosphoesterase superfamily Tharo_1415 e02955222263cf1d9eee70b8c2af6813 571 Gene3D G3DSA:3.90.1640.30 53 327 1.8E-84 T 14-10-2018 Tharo_1415 e02955222263cf1d9eee70b8c2af6813 571 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 27 566 1.4E-139 T 14-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 Tharo_1415 e02955222263cf1d9eee70b8c2af6813 571 Gene3D G3DSA:3.10.310.30 329 460 2.1E-30 T 14-10-2018 Tharo_1415 e02955222263cf1d9eee70b8c2af6813 571 Pfam PF02272 DHHA1 domain 323 454 1.3E-23 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 Tharo_1415 e02955222263cf1d9eee70b8c2af6813 571 Pfam PF01368 DHH family 79 178 2.6E-8 T 14-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Tharo_0905 722ff06f9f693d0aff4267d70619e5ba 150 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 106 123 - T 14-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Tharo_0905 722ff06f9f693d0aff4267d70619e5ba 150 SUPERFAMILY SSF51230 74 149 4.06E-25 T 14-10-2018 IPR011053 Single hybrid motif Tharo_0905 722ff06f9f693d0aff4267d70619e5ba 150 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 149 1.0E-52 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 Tharo_0905 722ff06f9f693d0aff4267d70619e5ba 150 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 96 110 1.5E-15 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 Tharo_0905 722ff06f9f693d0aff4267d70619e5ba 150 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 79 92 1.5E-15 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 Tharo_0905 722ff06f9f693d0aff4267d70619e5ba 150 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 111 124 1.5E-15 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 Tharo_0905 722ff06f9f693d0aff4267d70619e5ba 150 Pfam PF00364 Biotin-requiring enzyme 76 149 3.2E-24 T 14-10-2018 IPR000089 Biotin/lipoyl attachment Tharo_0905 722ff06f9f693d0aff4267d70619e5ba 150 Gene3D G3DSA:2.40.50.100 72 149 3.3E-31 T 14-10-2018 Tharo_0762 5427b61ce38187ce1d7b334898784ed9 283 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 249 275 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_0762 5427b61ce38187ce1d7b334898784ed9 283 PRINTS PR00046 Major sigma-70 factor signature 229 241 3.8E-19 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_0762 5427b61ce38187ce1d7b334898784ed9 283 PRINTS PR00046 Major sigma-70 factor signature 264 275 3.8E-19 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_0762 5427b61ce38187ce1d7b334898784ed9 283 PRINTS PR00046 Major sigma-70 factor signature 249 264 3.8E-19 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_0762 5427b61ce38187ce1d7b334898784ed9 283 PRINTS PR00046 Major sigma-70 factor signature 76 89 3.8E-19 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_0762 5427b61ce38187ce1d7b334898784ed9 283 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 1 281 51.286 T 14-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 Tharo_0762 5427b61ce38187ce1d7b334898784ed9 283 Pfam PF04545 Sigma-70, region 4 225 276 2.6E-16 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 Tharo_0762 5427b61ce38187ce1d7b334898784ed9 283 Pfam PF00140 Sigma-70 factor, region 1.2 14 42 4.4E-6 T 14-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Tharo_0762 5427b61ce38187ce1d7b334898784ed9 283 PIRSF PIRSF000770 8 282 3.4E-32 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_0762 5427b61ce38187ce1d7b334898784ed9 283 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 47 278 2.9E-31 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Tharo_0762 5427b61ce38187ce1d7b334898784ed9 283 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 13 280 4.6E-123 T 14-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 Tharo_0762 5427b61ce38187ce1d7b334898784ed9 283 SUPERFAMILY SSF88659 187 280 1.57E-18 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Tharo_0762 5427b61ce38187ce1d7b334898784ed9 283 SUPERFAMILY SSF88946 13 121 1.44E-39 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Tharo_0762 5427b61ce38187ce1d7b334898784ed9 283 Gene3D G3DSA:1.10.601.10 13 124 1.0E-28 T 14-10-2018 Tharo_0762 5427b61ce38187ce1d7b334898784ed9 283 Gene3D G3DSA:1.20.140.160 145 281 2.7E-16 T 14-10-2018 Tharo_0762 5427b61ce38187ce1d7b334898784ed9 283 Pfam PF04542 Sigma-70 region 2 52 121 1.2E-17 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Tharo_0762 5427b61ce38187ce1d7b334898784ed9 283 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 76 89 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_0329 63898bd1937a15859962d8813c2f7688 251 Pfam PF13144 Chaperone for flagella basal body P-ring formation 54 245 6.8E-39 T 14-10-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal Tharo_0329 63898bd1937a15859962d8813c2f7688 251 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 117 246 1.9E-33 T 14-10-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal Tharo_0329 63898bd1937a15859962d8813c2f7688 251 Gene3D G3DSA:2.30.30.760 193 250 6.9E-12 T 14-10-2018 Tharo_0329 63898bd1937a15859962d8813c2f7688 251 SMART SM00858 127 189 1.2E-12 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 Tharo_2506 38c414bf47b22f12893d6bf080984c3f 338 PIRSF PIRSF000116 201 333 7.6E-14 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Tharo_2506 38c414bf47b22f12893d6bf080984c3f 338 PIRSF PIRSF000116 3 204 1.0E-49 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Tharo_2506 38c414bf47b22f12893d6bf080984c3f 338 Gene3D G3DSA:1.10.3730.40 182 338 3.6E-72 T 14-10-2018 Tharo_2506 38c414bf47b22f12893d6bf080984c3f 338 SUPERFAMILY SSF48179 183 331 1.87E-68 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Tharo_2506 38c414bf47b22f12893d6bf080984c3f 338 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 2.6E-74 T 14-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Tharo_2506 38c414bf47b22f12893d6bf080984c3f 338 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 327 3.2E-132 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Tharo_2506 38c414bf47b22f12893d6bf080984c3f 338 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 3.8E-62 T 14-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Tharo_2506 38c414bf47b22f12893d6bf080984c3f 338 SUPERFAMILY SSF51735 1 182 3.21E-75 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_2506 38c414bf47b22f12893d6bf080984c3f 338 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 328 44.858 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Tharo_2506 38c414bf47b22f12893d6bf080984c3f 338 Gene3D G3DSA:3.40.50.720 1 181 8.9E-79 T 14-10-2018 Tharo_1575 8b3873c70defc8a45bab42f558d68fd9 257 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 78 257 1.1E-97 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Tharo_1575 8b3873c70defc8a45bab42f558d68fd9 257 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 1 78 1.5E-37 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Tharo_1575 8b3873c70defc8a45bab42f558d68fd9 257 Hamap MF_00008 Thymidylate synthase [thyA]. 1 257 37.644 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Tharo_1575 8b3873c70defc8a45bab42f558d68fd9 257 Gene3D G3DSA:3.30.572.10 1 257 5.5E-128 T 14-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Tharo_1575 8b3873c70defc8a45bab42f558d68fd9 257 PRINTS PR00108 Thymidylate synthase family signature 152 178 2.1E-47 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Tharo_1575 8b3873c70defc8a45bab42f558d68fd9 257 PRINTS PR00108 Thymidylate synthase family signature 108 127 2.1E-47 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Tharo_1575 8b3873c70defc8a45bab42f558d68fd9 257 PRINTS PR00108 Thymidylate synthase family signature 190 207 2.1E-47 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Tharo_1575 8b3873c70defc8a45bab42f558d68fd9 257 PRINTS PR00108 Thymidylate synthase family signature 35 56 2.1E-47 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Tharo_1575 8b3873c70defc8a45bab42f558d68fd9 257 PRINTS PR00108 Thymidylate synthase family signature 134 149 2.1E-47 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Tharo_1575 8b3873c70defc8a45bab42f558d68fd9 257 SUPERFAMILY SSF55831 2 257 1.31E-124 T 14-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Tharo_1575 8b3873c70defc8a45bab42f558d68fd9 257 ProSitePatterns PS00091 Thymidylate synthase active site. 119 147 - T 14-10-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Tharo_1575 8b3873c70defc8a45bab42f558d68fd9 257 Pfam PF00303 Thymidylate synthase 1 257 2.6E-121 T 14-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Tharo_2898 7e265abde98dacd875bd7980089286a5 90 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 3.8E-21 T 14-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 Tharo_2898 7e265abde98dacd875bd7980089286a5 90 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 75 25.254 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 Tharo_2898 7e265abde98dacd875bd7980089286a5 90 Gene3D G3DSA:2.40.50.140 1 71 7.8E-30 T 14-10-2018 Tharo_2898 7e265abde98dacd875bd7980089286a5 90 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 9.1E-30 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 Tharo_2898 7e265abde98dacd875bd7980089286a5 90 SUPERFAMILY SSF50249 1 71 3.14E-24 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_3297 098a52edde0d40cbcef93e5671dc5cbd 629 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 364 377 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Tharo_3297 098a52edde0d40cbcef93e5671dc5cbd 629 SUPERFAMILY SSF46689 593 628 8.17E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_3297 098a52edde0d40cbcef93e5671dc5cbd 629 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 595 612 6.7E-8 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_3297 098a52edde0d40cbcef93e5671dc5cbd 629 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 612 629 6.7E-8 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_3297 098a52edde0d40cbcef93e5671dc5cbd 629 Pfam PF00158 Sigma-54 interaction domain 351 507 5.4E-61 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Tharo_3297 098a52edde0d40cbcef93e5671dc5cbd 629 Gene3D G3DSA:1.10.10.60 593 629 4.5E-12 T 14-10-2018 Tharo_3297 098a52edde0d40cbcef93e5671dc5cbd 629 SUPERFAMILY SSF52540 350 582 2.66E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3297 098a52edde0d40cbcef93e5671dc5cbd 629 Pfam PF02954 Bacterial regulatory protein, Fis family 599 627 1.0E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_3297 098a52edde0d40cbcef93e5671dc5cbd 629 SMART SM00382 360 504 1.1E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_3297 098a52edde0d40cbcef93e5671dc5cbd 629 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 551 560 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Tharo_3297 098a52edde0d40cbcef93e5671dc5cbd 629 Gene3D G3DSA:3.40.50.300 348 512 6.1E-56 T 14-10-2018 Tharo_3297 098a52edde0d40cbcef93e5671dc5cbd 629 Gene3D G3DSA:1.10.8.60 513 588 1.7E-9 T 14-10-2018 Tharo_3297 098a52edde0d40cbcef93e5671dc5cbd 629 Gene3D G3DSA:3.30.450.40 19 204 4.7E-48 T 14-10-2018 IPR029016 GAF-like domain superfamily Tharo_3290 bb280f2eb3610c4b94dbea8f4c5f6fd2 91 Gene3D G3DSA:4.10.520.10 1 91 1.3E-34 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Tharo_3290 bb280f2eb3610c4b94dbea8f4c5f6fd2 91 SUPERFAMILY SSF47729 1 90 1.03E-30 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Tharo_3290 bb280f2eb3610c4b94dbea8f4c5f6fd2 91 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 9.7E-16 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Tharo_3290 bb280f2eb3610c4b94dbea8f4c5f6fd2 91 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 9.7E-16 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Tharo_3290 bb280f2eb3610c4b94dbea8f4c5f6fd2 91 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 9.7E-16 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Tharo_3290 bb280f2eb3610c4b94dbea8f4c5f6fd2 91 Pfam PF00216 Bacterial DNA-binding protein 1 90 2.1E-31 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Tharo_3290 bb280f2eb3610c4b94dbea8f4c5f6fd2 91 SMART SM00411 1 90 2.3E-41 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Tharo_3290 bb280f2eb3610c4b94dbea8f4c5f6fd2 91 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 Tharo_2483 b801db023815c1ad0ca914140b3a2216 70 Gene3D G3DSA:1.20.5.1150 16 54 1.8E-19 T 14-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2483 b801db023815c1ad0ca914140b3a2216 70 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 14-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2483 b801db023815c1ad0ca914140b3a2216 70 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 4.9E-23 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2483 b801db023815c1ad0ca914140b3a2216 70 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 1.2E-15 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2483 b801db023815c1ad0ca914140b3a2216 70 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 1.2E-15 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2483 b801db023815c1ad0ca914140b3a2216 70 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 1.2E-15 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2483 b801db023815c1ad0ca914140b3a2216 70 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 1.2E-15 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2483 b801db023815c1ad0ca914140b3a2216 70 Pfam PF01165 Ribosomal protein S21 4 56 3.8E-20 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2483 b801db023815c1ad0ca914140b3a2216 70 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.191 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2483 b801db023815c1ad0ca914140b3a2216 70 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 57 6.0E-14 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2464 0c704737e4b4fc1085f325f61f511c69 1291 SUPERFAMILY SSF90123 730 1041 1.07E-47 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Tharo_2464 0c704737e4b4fc1085f325f61f511c69 1291 Gene3D G3DSA:3.40.50.300 344 571 3.8E-53 T 14-10-2018 Tharo_2464 0c704737e4b4fc1085f325f61f511c69 1291 SUPERFAMILY SSF90123 36 340 8.89E-45 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Tharo_2464 0c704737e4b4fc1085f325f61f511c69 1291 SMART SM00382 374 560 2.0E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2464 0c704737e4b4fc1085f325f61f511c69 1291 SMART SM00382 1084 1271 1.6E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2464 0c704737e4b4fc1085f325f61f511c69 1291 Gene3D G3DSA:3.40.50.300 1047 1286 1.2E-63 T 14-10-2018 Tharo_2464 0c704737e4b4fc1085f325f61f511c69 1291 Pfam PF00005 ABC transporter 367 512 1.3E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_2464 0c704737e4b4fc1085f325f61f511c69 1291 SUPERFAMILY SSF52540 1050 1282 4.0E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2464 0c704737e4b4fc1085f325f61f511c69 1291 Gene3D G3DSA:1.20.1560.10 29 335 1.7E-46 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Tharo_2464 0c704737e4b4fc1085f325f61f511c69 1291 Gene3D G3DSA:1.20.1560.10 730 1043 1.0E-46 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Tharo_2464 0c704737e4b4fc1085f325f61f511c69 1291 SUPERFAMILY SSF52540 338 567 7.74E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2464 0c704737e4b4fc1085f325f61f511c69 1291 Pfam PF00005 ABC transporter 1077 1224 4.1E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_2464 0c704737e4b4fc1085f325f61f511c69 1291 Pfam PF00664 ABC transporter transmembrane region 743 1005 9.3E-22 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Tharo_2464 0c704737e4b4fc1085f325f61f511c69 1291 Pfam PF00664 ABC transporter transmembrane region 40 298 1.2E-19 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Tharo_2258 bf59a098c712096711ac7ae1ac9f6e93 972 Pfam PF02867 Ribonucleotide reductase, barrel domain 106 598 7.0E-138 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Tharo_2258 bf59a098c712096711ac7ae1ac9f6e93 972 PRINTS PR01183 Ribonucleotide reductase large chain signature 187 206 1.4E-23 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Tharo_2258 bf59a098c712096711ac7ae1ac9f6e93 972 PRINTS PR01183 Ribonucleotide reductase large chain signature 382 404 1.4E-23 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Tharo_2258 bf59a098c712096711ac7ae1ac9f6e93 972 PRINTS PR01183 Ribonucleotide reductase large chain signature 344 367 1.4E-23 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Tharo_2258 bf59a098c712096711ac7ae1ac9f6e93 972 PRINTS PR01183 Ribonucleotide reductase large chain signature 306 317 1.4E-23 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Tharo_2258 bf59a098c712096711ac7ae1ac9f6e93 972 PRINTS PR01183 Ribonucleotide reductase large chain signature 466 493 1.4E-23 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Tharo_2258 bf59a098c712096711ac7ae1ac9f6e93 972 PRINTS PR01183 Ribonucleotide reductase large chain signature 410 433 1.4E-23 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Tharo_2258 bf59a098c712096711ac7ae1ac9f6e93 972 SUPERFAMILY SSF51998 28 618 9.16E-173 T 14-10-2018 Tharo_2258 bf59a098c712096711ac7ae1ac9f6e93 972 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 47 606 1.8E-177 T 14-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Tharo_2258 bf59a098c712096711ac7ae1ac9f6e93 972 Gene3D G3DSA:3.20.70.20 21 613 8.8E-189 T 14-10-2018 Tharo_2584 f71a7269425fb0516c9185c69c07f436 459 Gene3D G3DSA:3.40.50.1220 273 457 7.9E-79 T 14-10-2018 Tharo_2584 f71a7269425fb0516c9185c69c07f436 459 Pfam PF02233 NAD(P) transhydrogenase beta subunit 8 452 3.1E-165 T 14-10-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 Tharo_2584 f71a7269425fb0516c9185c69c07f436 459 SUPERFAMILY SSF52467 281 455 1.31E-68 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Tharo_2584 f71a7269425fb0516c9185c69c07f436 459 PIRSF PIRSF000204 2 456 4.8E-153 T 14-10-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 Tharo_0498 edbd3f4f8d0f9a3737bf81f3f85198c3 1394 SUPERFAMILY SSF52540 78 607 1.83E-87 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0498 edbd3f4f8d0f9a3737bf81f3f85198c3 1394 Gene3D G3DSA:3.40.50.300 47 260 4.4E-70 T 14-10-2018 Tharo_0498 edbd3f4f8d0f9a3737bf81f3f85198c3 1394 Gene3D G3DSA:3.40.50.300 261 438 4.7E-54 T 14-10-2018 Tharo_0498 edbd3f4f8d0f9a3737bf81f3f85198c3 1394 Gene3D G3DSA:1.20.120.1080 467 563 6.4E-15 T 14-10-2018 Tharo_0498 edbd3f4f8d0f9a3737bf81f3f85198c3 1394 Pfam PF04408 Helicase associated domain (HA2) 485 570 5.0E-15 T 14-10-2018 IPR007502 Helicase-associated domain GO:0004386 Tharo_0498 edbd3f4f8d0f9a3737bf81f3f85198c3 1394 SMART SM00490 320 421 6.2E-12 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_0498 edbd3f4f8d0f9a3737bf81f3f85198c3 1394 SMART SM00487 78 267 2.4E-21 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Tharo_0498 edbd3f4f8d0f9a3737bf81f3f85198c3 1394 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 640 725 3.7E-14 T 14-10-2018 IPR011709 Domain of unknown function DUF1605 Tharo_0498 edbd3f4f8d0f9a3737bf81f3f85198c3 1394 Pfam PF00271 Helicase conserved C-terminal domain 305 420 2.1E-9 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_0498 edbd3f4f8d0f9a3737bf81f3f85198c3 1394 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 16 1042 0.0 T 14-10-2018 IPR010222 RNA helicase HrpA GO:0004004 Tharo_0498 edbd3f4f8d0f9a3737bf81f3f85198c3 1394 Pfam PF11898 Domain of unknown function (DUF3418) 740 1390 5.4E-193 T 14-10-2018 IPR024590 RNA helicase HrpA, C-terminal Tharo_0498 edbd3f4f8d0f9a3737bf81f3f85198c3 1394 SMART SM00847 481 577 2.0E-31 T 14-10-2018 IPR007502 Helicase-associated domain GO:0004386 Tharo_3372 630ba9a95b441fdd39bf3048a6a78029 355 Gene3D G3DSA:3.40.50.720 151 300 1.5E-72 T 14-10-2018 Tharo_3372 630ba9a95b441fdd39bf3048a6a78029 355 SUPERFAMILY SSF51735 141 321 5.3E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_3372 630ba9a95b441fdd39bf3048a6a78029 355 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 133 7.2E-23 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Tharo_3372 630ba9a95b441fdd39bf3048a6a78029 355 TIGRFAM TIGR03201 dearomat_had: 6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase 8 353 5.4E-163 T 14-10-2018 IPR017614 6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase KEGG: 00362+1.1.1.368|MetaCyc: PWY-7401 Tharo_3372 630ba9a95b441fdd39bf3048a6a78029 355 SUPERFAMILY SSF50129 11 175 7.08E-33 T 14-10-2018 IPR011032 GroES-like superfamily Tharo_3372 630ba9a95b441fdd39bf3048a6a78029 355 Gene3D G3DSA:3.90.180.10 19 347 1.5E-72 T 14-10-2018 Tharo_3372 630ba9a95b441fdd39bf3048a6a78029 355 Pfam PF00107 Zinc-binding dehydrogenase 179 314 7.7E-23 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Tharo_1252 6ffb3f34d084ea8b92b137c6bff1b12b 478 Pfam PF13193 AMP-binding enzyme C-terminal domain 389 466 1.2E-5 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Tharo_1252 6ffb3f34d084ea8b92b137c6bff1b12b 478 ProSitePatterns PS00455 Putative AMP-binding domain signature. 144 155 - T 14-10-2018 IPR020845 AMP-binding, conserved site Tharo_1252 6ffb3f34d084ea8b92b137c6bff1b12b 478 SUPERFAMILY SSF56801 7 475 2.75E-90 T 14-10-2018 Tharo_1252 6ffb3f34d084ea8b92b137c6bff1b12b 478 Gene3D G3DSA:3.30.300.30 373 476 8.7E-12 T 14-10-2018 Tharo_1252 6ffb3f34d084ea8b92b137c6bff1b12b 478 Pfam PF00501 AMP-binding enzyme 9 379 3.5E-54 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Tharo_1252 6ffb3f34d084ea8b92b137c6bff1b12b 478 Gene3D G3DSA:3.40.50.12780 4 372 3.4E-74 T 14-10-2018 Tharo_1729 4d8520d58003cc89c965137f785fb1f7 182 Gene3D G3DSA:1.20.120.700 5 173 1.4E-12 T 14-10-2018 Tharo_1729 4d8520d58003cc89c965137f785fb1f7 182 Gene3D G3DSA:1.10.4070.10 79 160 1.4E-12 T 14-10-2018 Tharo_1729 4d8520d58003cc89c965137f785fb1f7 182 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 53 171 2.9E-29 T 14-10-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 Tharo_1729 4d8520d58003cc89c965137f785fb1f7 182 SUPERFAMILY SSF89155 2 171 4.32E-29 T 14-10-2018 IPR036411 TorD-like superfamily Tharo_1729 4d8520d58003cc89c965137f785fb1f7 182 Pfam PF02613 Nitrate reductase delta subunit 56 164 4.2E-11 T 14-10-2018 IPR020945 DMSO/Nitrate reductase chaperone Tharo_1645 a54bed318a34c48edff0649a4f06a4f3 306 SUPERFAMILY SSF52540 11 214 5.08E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1645 a54bed318a34c48edff0649a4f06a4f3 306 Pfam PF00005 ABC transporter 27 159 2.3E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_1645 a54bed318a34c48edff0649a4f06a4f3 306 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_1645 a54bed318a34c48edff0649a4f06a4f3 306 SMART SM00382 35 209 4.7E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1645 a54bed318a34c48edff0649a4f06a4f3 306 Gene3D G3DSA:3.40.50.300 10 242 5.4E-57 T 14-10-2018 Tharo_0246 a69611e5a7d3d96318168f592c04d424 433 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 429 1.2E-103 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 Tharo_0246 a69611e5a7d3d96318168f592c04d424 433 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 422 7.1E-97 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit Tharo_0246 a69611e5a7d3d96318168f592c04d424 433 PIRSF PIRSF006066 7 433 8.4E-98 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 Tharo_1250 cb5b865d8f7ebac280d60d7cebd97af2 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 4.4E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1250 cb5b865d8f7ebac280d60d7cebd97af2 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 4.4E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1250 cb5b865d8f7ebac280d60d7cebd97af2 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 4.4E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1250 cb5b865d8f7ebac280d60d7cebd97af2 299 SUPERFAMILY SSF53850 88 294 8.01E-44 T 14-10-2018 Tharo_1250 cb5b865d8f7ebac280d60d7cebd97af2 299 Gene3D G3DSA:3.40.190.10 90 290 2.1E-59 T 14-10-2018 Tharo_1250 cb5b865d8f7ebac280d60d7cebd97af2 299 SUPERFAMILY SSF46785 2 84 3.43E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1250 cb5b865d8f7ebac280d60d7cebd97af2 299 Gene3D G3DSA:1.10.10.10 1 86 2.8E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1250 cb5b865d8f7ebac280d60d7cebd97af2 299 Gene3D G3DSA:3.40.190.10 169 267 2.1E-59 T 14-10-2018 Tharo_1250 cb5b865d8f7ebac280d60d7cebd97af2 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 5.1E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1250 cb5b865d8f7ebac280d60d7cebd97af2 299 Pfam PF03466 LysR substrate binding domain 93 296 1.5E-27 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_2510 9378cc2befcb3236fa96dce1c93d8776 199 Pfam PF03358 NADPH-dependent FMN reductase 7 125 2.5E-7 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Tharo_2510 9378cc2befcb3236fa96dce1c93d8776 199 SUPERFAMILY SSF52218 1 195 7.08E-58 T 14-10-2018 IPR029039 Flavoprotein-like superfamily Tharo_2510 9378cc2befcb3236fa96dce1c93d8776 199 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 4 194 1.4E-47 T 14-10-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 Tharo_2510 9378cc2befcb3236fa96dce1c93d8776 199 Gene3D G3DSA:3.40.50.360 1 196 7.4E-63 T 14-10-2018 IPR029039 Flavoprotein-like superfamily Tharo_2469 0a19a45b60bcebab9f17dd4545474c1d 741 Pfam PF13361 UvrD-like helicase C-terminal domain 278 617 2.3E-71 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Tharo_2469 0a19a45b60bcebab9f17dd4545474c1d 741 Gene3D G3DSA:3.40.50.300 8 273 3.2E-90 T 14-10-2018 Tharo_2469 0a19a45b60bcebab9f17dd4545474c1d 741 Gene3D G3DSA:1.10.10.160 112 184 3.2E-90 T 14-10-2018 IPR013986 DExx box DNA helicase domain superfamily Tharo_2469 0a19a45b60bcebab9f17dd4545474c1d 741 Pfam PF00580 UvrD/REP helicase N-terminal domain 8 272 1.1E-71 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 Tharo_2469 0a19a45b60bcebab9f17dd4545474c1d 741 Gene3D G3DSA:3.40.50.300 281 634 1.1E-117 T 14-10-2018 Tharo_2469 0a19a45b60bcebab9f17dd4545474c1d 741 Gene3D G3DSA:1.10.486.10 383 547 1.1E-117 T 14-10-2018 Tharo_2469 0a19a45b60bcebab9f17dd4545474c1d 741 SUPERFAMILY SSF52540 1 640 3.52E-173 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2919 a2ecd7045d1892bbe725dcfff158bd17 460 SUPERFAMILY SSF51246 330 443 1.52E-39 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 Tharo_2919 a2ecd7045d1892bbe725dcfff158bd17 460 Pfam PF02785 Biotin carboxylase C-terminal domain 335 439 5.5E-38 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Tharo_2919 a2ecd7045d1892bbe725dcfff158bd17 460 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 321 1.7E-68 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Tharo_2919 a2ecd7045d1892bbe725dcfff158bd17 460 SUPERFAMILY SSF52440 2 112 7.05E-43 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Tharo_2919 a2ecd7045d1892bbe725dcfff158bd17 460 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Tharo_2919 a2ecd7045d1892bbe725dcfff158bd17 460 SMART SM00878 335 441 7.5E-57 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Tharo_2919 a2ecd7045d1892bbe725dcfff158bd17 460 SUPERFAMILY SSF56059 84 351 2.3E-69 T 14-10-2018 Tharo_2919 a2ecd7045d1892bbe725dcfff158bd17 460 Pfam PF00289 Biotin carboxylase, N-terminal domain 3 110 2.0E-42 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Tharo_2919 a2ecd7045d1892bbe725dcfff158bd17 460 Gene3D G3DSA:3.30.470.130 1 445 2.9E-181 T 14-10-2018 Tharo_1880 52c88d5185365d0496327d9c16b2c16c 235 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 11 228 2.2E-83 T 14-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 Tharo_1880 52c88d5185365d0496327d9c16b2c16c 235 Gene3D G3DSA:3.40.50.150 11 233 4.3E-74 T 14-10-2018 Tharo_1880 52c88d5185365d0496327d9c16b2c16c 235 Pfam PF13489 Methyltransferase domain 51 202 2.6E-26 T 14-10-2018 Tharo_1880 52c88d5185365d0496327d9c16b2c16c 235 SUPERFAMILY SSF53335 14 227 5.52E-48 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_1880 52c88d5185365d0496327d9c16b2c16c 235 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 11 234 37.461 T 14-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 Tharo_2167 2747885fe4597d9bf5553e12bda020a9 257 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 3 257 1.2E-97 T 14-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 Tharo_2167 2747885fe4597d9bf5553e12bda020a9 257 Pfam PF00753 Metallo-beta-lactamase superfamily 12 169 1.8E-18 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_2167 2747885fe4597d9bf5553e12bda020a9 257 Gene3D G3DSA:3.60.15.10 1 257 2.6E-84 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_2167 2747885fe4597d9bf5553e12bda020a9 257 SMART SM00849 11 169 4.8E-32 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_2167 2747885fe4597d9bf5553e12bda020a9 257 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 1 257 43.105 T 14-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 Tharo_2167 2747885fe4597d9bf5553e12bda020a9 257 SUPERFAMILY SSF56281 1 257 1.76E-70 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_2167 2747885fe4597d9bf5553e12bda020a9 257 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 170 257 1.8E-25 T 14-10-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 Tharo_2167 2747885fe4597d9bf5553e12bda020a9 257 PIRSF PIRSF005457 1 257 2.4E-97 T 14-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 Tharo_0991 b45359ee0c51a44678febfaf7979b581 422 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 18 412 29.719 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 Tharo_0991 b45359ee0c51a44678febfaf7979b581 422 Gene3D G3DSA:3.20.20.20 17 303 7.1E-98 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_0991 b45359ee0c51a44678febfaf7979b581 422 Gene3D G3DSA:3.30.413.10 304 421 2.4E-35 T 14-10-2018 Tharo_0991 b45359ee0c51a44678febfaf7979b581 422 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 20 409 2.3E-122 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 Tharo_0991 b45359ee0c51a44678febfaf7979b581 422 PIRSF PIRSF004640 15 420 2.4E-131 T 14-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 Tharo_0991 b45359ee0c51a44678febfaf7979b581 422 Pfam PF04551 GcpE protein 23 409 1.0E-111 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 Tharo_1131 c97b162aec969ac1311c3f42b8d00560 303 SMART SM00530 35 90 4.5E-9 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_1131 c97b162aec969ac1311c3f42b8d00560 303 SUPERFAMILY SSF47413 26 97 1.86E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_1131 c97b162aec969ac1311c3f42b8d00560 303 Gene3D G3DSA:3.40.50.300 120 303 4.2E-46 T 14-10-2018 Tharo_1131 c97b162aec969ac1311c3f42b8d00560 303 ProSitePatterns PS01128 Shikimate kinase signature. 191 217 - T 14-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 Tharo_1131 c97b162aec969ac1311c3f42b8d00560 303 SUPERFAMILY SSF52540 136 301 6.17E-27 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1131 c97b162aec969ac1311c3f42b8d00560 303 Pfam PF01202 Shikimate kinase 144 297 1.0E-39 T 14-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 Tharo_1131 c97b162aec969ac1311c3f42b8d00560 303 Gene3D G3DSA:1.10.260.40 15 98 1.6E-14 T 14-10-2018 Tharo_1131 c97b162aec969ac1311c3f42b8d00560 303 PRINTS PR01100 Shikimate kinase family signature 190 198 2.9E-16 T 14-10-2018 Tharo_1131 c97b162aec969ac1311c3f42b8d00560 303 PRINTS PR01100 Shikimate kinase family signature 162 175 2.9E-16 T 14-10-2018 Tharo_1131 c97b162aec969ac1311c3f42b8d00560 303 PRINTS PR01100 Shikimate kinase family signature 209 218 2.9E-16 T 14-10-2018 Tharo_1131 c97b162aec969ac1311c3f42b8d00560 303 PRINTS PR01100 Shikimate kinase family signature 230 247 2.9E-16 T 14-10-2018 Tharo_1131 c97b162aec969ac1311c3f42b8d00560 303 PRINTS PR01100 Shikimate kinase family signature 138 153 2.9E-16 T 14-10-2018 Tharo_1131 c97b162aec969ac1311c3f42b8d00560 303 Pfam PF01381 Helix-turn-helix 36 90 5.2E-9 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_1131 c97b162aec969ac1311c3f42b8d00560 303 Hamap MF_00109 Shikimate kinase [aroK]. 135 302 23.415 T 14-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 Tharo_2331 28c853e7877a1c7a416b21b9fe7feb5b 413 Gene3D G3DSA:2.70.70.10 248 378 4.2E-91 T 14-10-2018 IPR011055 Duplicated hybrid motif Tharo_2331 28c853e7877a1c7a416b21b9fe7feb5b 413 SUPERFAMILY SSF51261 145 374 8.89E-67 T 14-10-2018 IPR011055 Duplicated hybrid motif Tharo_2331 28c853e7877a1c7a416b21b9fe7feb5b 413 Gene3D G3DSA:3.10.450.350 151 393 4.2E-91 T 14-10-2018 Tharo_2331 28c853e7877a1c7a416b21b9fe7feb5b 413 Gene3D G3DSA:3.10.450.350 42 130 1.2E-11 T 14-10-2018 Tharo_2331 28c853e7877a1c7a416b21b9fe7feb5b 413 Pfam PF01551 Peptidase family M23 276 372 1.4E-31 T 14-10-2018 IPR016047 Peptidase M23 Tharo_0778 f5ef48499b17d373d51420885220748c 1025 Gene3D G3DSA:3.30.70.1430 559 660 9.7E-246 T 14-10-2018 Tharo_0778 f5ef48499b17d373d51420885220748c 1025 Pfam PF00873 AcrB/AcrD/AcrF family 16 1018 7.6E-153 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_0778 f5ef48499b17d373d51420885220748c 1025 Gene3D G3DSA:3.30.2090.10 180 269 9.7E-246 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_0778 f5ef48499b17d373d51420885220748c 1025 Gene3D G3DSA:3.30.2090.10 711 799 9.7E-246 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_0778 f5ef48499b17d373d51420885220748c 1025 SUPERFAMILY SSF82866 799 1021 9.42E-42 T 14-10-2018 Tharo_0778 f5ef48499b17d373d51420885220748c 1025 SUPERFAMILY SSF82714 713 795 1.01E-9 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_0778 f5ef48499b17d373d51420885220748c 1025 SUPERFAMILY SSF82714 184 266 6.15E-8 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_0778 f5ef48499b17d373d51420885220748c 1025 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 5.9E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_0778 f5ef48499b17d373d51420885220748c 1025 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 5.9E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_0778 f5ef48499b17d373d51420885220748c 1025 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 5.9E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_0778 f5ef48499b17d373d51420885220748c 1025 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 5.9E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_0778 f5ef48499b17d373d51420885220748c 1025 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 5.9E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_0778 f5ef48499b17d373d51420885220748c 1025 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 5.9E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_0778 f5ef48499b17d373d51420885220748c 1025 SUPERFAMILY SSF82866 290 487 6.15E-34 T 14-10-2018 Tharo_0778 f5ef48499b17d373d51420885220748c 1025 SUPERFAMILY SSF82693 41 137 1.65E-15 T 14-10-2018 Tharo_0778 f5ef48499b17d373d51420885220748c 1025 Gene3D G3DSA:3.30.70.1320 138 327 9.7E-246 T 14-10-2018 Tharo_0778 f5ef48499b17d373d51420885220748c 1025 Gene3D G3DSA:3.30.70.1430 41 807 9.7E-246 T 14-10-2018 Tharo_0778 f5ef48499b17d373d51420885220748c 1025 Gene3D G3DSA:1.20.1640.10 14 502 9.7E-246 T 14-10-2018 Tharo_0778 f5ef48499b17d373d51420885220748c 1025 Gene3D G3DSA:3.30.70.1440 661 859 9.7E-246 T 14-10-2018 Tharo_0778 f5ef48499b17d373d51420885220748c 1025 Gene3D G3DSA:1.20.1640.10 503 1016 9.7E-246 T 14-10-2018 Tharo_3089 ece4c9438052849ff8cf79a3f430a0d6 389 Pfam PF00108 Thiolase, N-terminal domain 7 220 2.4E-15 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 Tharo_3089 ece4c9438052849ff8cf79a3f430a0d6 389 Gene3D G3DSA:3.40.47.10 4 382 6.8E-103 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_3089 ece4c9438052849ff8cf79a3f430a0d6 389 Pfam PF02803 Thiolase, C-terminal domain 261 352 1.3E-9 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 Tharo_3089 ece4c9438052849ff8cf79a3f430a0d6 389 SUPERFAMILY SSF53901 226 356 5.97E-24 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_3089 ece4c9438052849ff8cf79a3f430a0d6 389 PIRSF PIRSF000429 1 377 2.1E-53 T 14-10-2018 IPR002155 Thiolase GO:0016747 Tharo_3089 ece4c9438052849ff8cf79a3f430a0d6 389 SUPERFAMILY SSF53901 7 227 8.52E-37 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_0760 c56f69de368a55a82cdd0359191b2440 298 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 16 294 2.8E-92 T 14-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 Tharo_0760 c56f69de368a55a82cdd0359191b2440 298 Pfam PF01040 UbiA prenyltransferase family 30 278 4.2E-58 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 Tharo_0760 c56f69de368a55a82cdd0359191b2440 298 Gene3D G3DSA:1.10.357.140 24 178 9.5E-16 T 14-10-2018 Tharo_0760 c56f69de368a55a82cdd0359191b2440 298 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 13 295 19.353 T 14-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 Tharo_0760 c56f69de368a55a82cdd0359191b2440 298 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 69 91 - T 14-10-2018 IPR030470 UbiA prenyltransferase conserved site Tharo_3063 7d895e06a59badc71c3b1212f72ea607 388 Pfam PF14870 Photosynthesis system II assembly factor YCF48 83 143 5.9E-9 T 14-10-2018 IPR028203 Photosynthesis system II assembly factor Ycf48/Hcf136-like domain Tharo_3063 7d895e06a59badc71c3b1212f72ea607 388 Pfam PF14870 Photosynthesis system II assembly factor YCF48 184 310 2.6E-12 T 14-10-2018 IPR028203 Photosynthesis system II assembly factor Ycf48/Hcf136-like domain Tharo_3063 7d895e06a59badc71c3b1212f72ea607 388 SUPERFAMILY SSF50939 69 373 1.71E-48 T 14-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 Tharo_3063 7d895e06a59badc71c3b1212f72ea607 388 Gene3D G3DSA:2.130.10.10 38 170 1.5E-8 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Tharo_3063 7d895e06a59badc71c3b1212f72ea607 388 Gene3D G3DSA:2.130.10.10 186 373 1.6E-19 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Tharo_0843 b4fa2581e00eeceff5459f99c0e30475 152 Pfam PF01575 MaoC like domain 30 124 2.7E-24 T 14-10-2018 IPR002539 MaoC-like dehydratase domain Tharo_0843 b4fa2581e00eeceff5459f99c0e30475 152 Gene3D G3DSA:3.10.129.10 11 151 6.6E-45 T 14-10-2018 Tharo_0843 b4fa2581e00eeceff5459f99c0e30475 152 SUPERFAMILY SSF54637 15 150 2.65E-42 T 14-10-2018 IPR029069 HotDog domain superfamily Tharo_1063 06b2a769c993ab50b9302bd58a0ba0fb 571 Gene3D G3DSA:3.30.450.90 159 294 1.2E-47 T 14-10-2018 Tharo_1063 06b2a769c993ab50b9302bd58a0ba0fb 571 SUPERFAMILY SSF160246 7 143 7.32E-32 T 14-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily Tharo_1063 06b2a769c993ab50b9302bd58a0ba0fb 571 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 47 148 2.0E-18 T 14-10-2018 IPR007831 General secretory system II, protein E, N-terminal Tharo_1063 06b2a769c993ab50b9302bd58a0ba0fb 571 Gene3D G3DSA:3.30.300.160 66 145 3.7E-10 T 14-10-2018 Tharo_1063 06b2a769c993ab50b9302bd58a0ba0fb 571 Gene3D G3DSA:3.40.50.300 297 571 3.3E-104 T 14-10-2018 Tharo_1063 06b2a769c993ab50b9302bd58a0ba0fb 571 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 389 403 - T 14-10-2018 IPR001482 Type II/IV secretion system protein Tharo_1063 06b2a769c993ab50b9302bd58a0ba0fb 571 TIGRFAM TIGR02538 type_IV_pilB: type IV-A pilus assembly ATPase PilB 11 570 2.7E-248 T 14-10-2018 IPR013374 ATPase, type IV, pilus assembly, PilB GO:0005524|GO:0008565|GO:0009297 Tharo_1063 06b2a769c993ab50b9302bd58a0ba0fb 571 SUPERFAMILY SSF52540 181 567 4.69E-94 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1063 06b2a769c993ab50b9302bd58a0ba0fb 571 Pfam PF00437 Type II/IV secretion system protein 195 461 3.6E-88 T 14-10-2018 IPR001482 Type II/IV secretion system protein Tharo_0564 b577f7173545c489355479065a4edb18 231 Pfam PF00005 ABC transporter 19 166 1.1E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_0564 b577f7173545c489355479065a4edb18 231 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_0564 b577f7173545c489355479065a4edb18 231 Gene3D G3DSA:3.40.50.300 1 227 4.2E-61 T 14-10-2018 Tharo_0564 b577f7173545c489355479065a4edb18 231 SUPERFAMILY SSF52540 1 221 4.11E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0564 b577f7173545c489355479065a4edb18 231 SMART SM00382 27 214 6.2E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2066 59f9d93c561ffb67374dbfd06ce82a46 298 Gene3D G3DSA:1.10.8.10 1 56 8.5E-23 T 14-10-2018 Tharo_2066 59f9d93c561ffb67374dbfd06ce82a46 298 Gene3D G3DSA:3.30.479.20 57 149 2.4E-26 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 Tharo_2066 59f9d93c561ffb67374dbfd06ce82a46 298 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 14-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Tharo_2066 59f9d93c561ffb67374dbfd06ce82a46 298 Hamap MF_00050 Elongation factor Ts [tsf]. 1 292 76.623 T 14-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Tharo_2066 59f9d93c561ffb67374dbfd06ce82a46 298 SUPERFAMILY SSF46934 3 56 3.98E-15 T 14-10-2018 IPR009060 UBA-like superfamily GO:0005515 Tharo_2066 59f9d93c561ffb67374dbfd06ce82a46 298 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 292 4.4E-91 T 14-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Tharo_2066 59f9d93c561ffb67374dbfd06ce82a46 298 SUPERFAMILY SSF54713 151 292 9.81E-45 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 Tharo_2066 59f9d93c561ffb67374dbfd06ce82a46 298 Pfam PF00889 Elongation factor TS 73 275 1.5E-67 T 14-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 Tharo_2066 59f9d93c561ffb67374dbfd06ce82a46 298 Gene3D G3DSA:1.10.286.20 192 238 7.1E-36 T 14-10-2018 Tharo_2066 59f9d93c561ffb67374dbfd06ce82a46 298 SUPERFAMILY SSF54713 56 147 1.57E-23 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 Tharo_2066 59f9d93c561ffb67374dbfd06ce82a46 298 Gene3D G3DSA:3.30.479.20 155 274 7.1E-36 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 Tharo_1680 9695b94fb470070d7ede91adda236e0d 86 Gene3D G3DSA:3.30.56.90 5 79 1.2E-35 T 14-10-2018 Tharo_1680 9695b94fb470070d7ede91adda236e0d 86 Pfam PF09996 Uncharacterized protein conserved in bacteria (DUF2237) 2 77 4.9E-33 T 14-10-2018 IPR018714 Protein of unknown function DUF2237 Tharo_3246 93dedbb00a23dfc1424164d851b41e1e 362 SUPERFAMILY SSF53756 1 357 1.57E-79 T 14-10-2018 Tharo_3246 93dedbb00a23dfc1424164d851b41e1e 362 Gene3D G3DSA:3.40.50.2000 175 316 7.7E-44 T 14-10-2018 Tharo_3246 93dedbb00a23dfc1424164d851b41e1e 362 Gene3D G3DSA:3.40.50.2000 1 162 6.9E-59 T 14-10-2018 Tharo_3246 93dedbb00a23dfc1424164d851b41e1e 362 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 76 321 9.2E-70 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 Tharo_3246 93dedbb00a23dfc1424164d851b41e1e 362 TIGRFAM TIGR02193 heptsyl_trn_I: lipopolysaccharide heptosyltransferase I 3 305 8.3E-110 T 14-10-2018 IPR011908 Lipopolysaccharide heptosyltransferase I GO:0008920|GO:0009244 Tharo_2274 659aeaecd305357a1e6863477ccfe10d 383 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 181 208 7.3E-16 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_2274 659aeaecd305357a1e6863477ccfe10d 383 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 210 239 7.3E-16 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_2274 659aeaecd305357a1e6863477ccfe10d 383 SUPERFAMILY SSF58104 94 330 3.01E-36 T 14-10-2018 Tharo_2274 659aeaecd305357a1e6863477ccfe10d 383 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 156 297 9.8E-23 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_2274 659aeaecd305357a1e6863477ccfe10d 383 SMART SM00283 95 338 1.7E-4 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_2274 659aeaecd305357a1e6863477ccfe10d 383 Gene3D G3DSA:1.10.287.950 69 339 1.4E-35 T 14-10-2018 Tharo_1874 9176e39c79e9cbadb6afe9694b5a2f06 260 Gene3D G3DSA:3.40.50.720 1 260 8.1E-86 T 14-10-2018 Tharo_1874 9176e39c79e9cbadb6afe9694b5a2f06 260 SUPERFAMILY SSF51735 9 259 1.65E-82 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1874 9176e39c79e9cbadb6afe9694b5a2f06 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Tharo_1874 9176e39c79e9cbadb6afe9694b5a2f06 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.4E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1874 9176e39c79e9cbadb6afe9694b5a2f06 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.4E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1874 9176e39c79e9cbadb6afe9694b5a2f06 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 2.4E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1874 9176e39c79e9cbadb6afe9694b5a2f06 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.4E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1874 9176e39c79e9cbadb6afe9694b5a2f06 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.4E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1874 9176e39c79e9cbadb6afe9694b5a2f06 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.4E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1874 9176e39c79e9cbadb6afe9694b5a2f06 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 6.5E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1874 9176e39c79e9cbadb6afe9694b5a2f06 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 6.5E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1874 9176e39c79e9cbadb6afe9694b5a2f06 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 6.5E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1874 9176e39c79e9cbadb6afe9694b5a2f06 260 PIRSF PIRSF000126 1 240 1.4E-52 T 14-10-2018 Tharo_1874 9176e39c79e9cbadb6afe9694b5a2f06 260 Pfam PF00106 short chain dehydrogenase 10 200 2.6E-64 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2784 5422ede71f6af6296b9efae58d358276 182 Gene3D G3DSA:3.90.79.10 36 163 2.2E-29 T 14-10-2018 Tharo_2784 5422ede71f6af6296b9efae58d358276 182 Pfam PF14803 Nudix N-terminal 4 32 6.9E-7 T 14-10-2018 IPR029401 Nudix hydrolase, N-terminal KEGG: 00230+3.6.1.13|KEGG: 00740+3.6.1.18 Tharo_2784 5422ede71f6af6296b9efae58d358276 182 PRINTS PR00502 NUDIX hydrolase family signature 79 94 1.1E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Tharo_2784 5422ede71f6af6296b9efae58d358276 182 PRINTS PR00502 NUDIX hydrolase family signature 65 79 1.1E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Tharo_2784 5422ede71f6af6296b9efae58d358276 182 ProSitePatterns PS00893 Nudix box signature. 70 91 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Tharo_2784 5422ede71f6af6296b9efae58d358276 182 SUPERFAMILY SSF55811 4 153 8.94E-34 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Tharo_2784 5422ede71f6af6296b9efae58d358276 182 Pfam PF00293 NUDIX domain 37 141 4.9E-14 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Tharo_1329 32d5d4d28b70c50939cfbc03610d61ad 90 Pfam PF04977 Septum formation initiator 11 89 9.1E-26 T 14-10-2018 IPR007060 Septum formation initiator FtsL/DivIC Tharo_1329 32d5d4d28b70c50939cfbc03610d61ad 90 Hamap MF_00599 Cell division protein FtsB [ftsB]. 1 90 33.457 T 14-10-2018 IPR023081 Cell division protein FtsB Tharo_1145 3d5bf59eec7c379de60a6b7d47d550bb 55 Gene3D G3DSA:2.20.28.10 1 54 1.2E-21 T 14-10-2018 Tharo_1145 3d5bf59eec7c379de60a6b7d47d550bb 55 Pfam PF00301 Rubredoxin 3 48 1.1E-18 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 Tharo_1145 3d5bf59eec7c379de60a6b7d47d550bb 55 SUPERFAMILY SSF57802 1 53 5.05E-19 T 14-10-2018 Tharo_1145 3d5bf59eec7c379de60a6b7d47d550bb 55 PRINTS PR00163 Rubredoxin signature 3 19 1.3E-5 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 Tharo_1145 3d5bf59eec7c379de60a6b7d47d550bb 55 PRINTS PR00163 Rubredoxin signature 33 49 1.3E-5 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 Tharo_0238 a951e3ac78898ed09d9fa53a1e979d50 305 Pfam PF03466 LysR substrate binding domain 91 292 6.9E-39 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_0238 a951e3ac78898ed09d9fa53a1e979d50 305 SUPERFAMILY SSF46785 3 113 3.78E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0238 a951e3ac78898ed09d9fa53a1e979d50 305 Gene3D G3DSA:1.10.10.10 3 93 5.5E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0238 a951e3ac78898ed09d9fa53a1e979d50 305 SUPERFAMILY SSF53850 92 297 1.71E-41 T 14-10-2018 Tharo_0238 a951e3ac78898ed09d9fa53a1e979d50 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 8.4E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0238 a951e3ac78898ed09d9fa53a1e979d50 305 Gene3D G3DSA:3.40.190.290 94 299 2.7E-41 T 14-10-2018 Tharo_0238 a951e3ac78898ed09d9fa53a1e979d50 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 8.2E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0238 a951e3ac78898ed09d9fa53a1e979d50 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 8.2E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0238 a951e3ac78898ed09d9fa53a1e979d50 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 8.2E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1328 34929098e97145363f386b4673c60910 427 SMART SM01192 139 425 3.1E-211 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Tharo_1328 34929098e97145363f386b4673c60910 427 ProSitePatterns PS00164 Enolase signature. 334 347 - T 14-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1328 34929098e97145363f386b4673c60910 427 SMART SM01193 4 134 5.6E-97 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Tharo_1328 34929098e97145363f386b4673c60910 427 Gene3D G3DSA:3.20.20.120 128 427 4.8E-130 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Tharo_1328 34929098e97145363f386b4673c60910 427 SUPERFAMILY SSF54826 3 136 1.94E-56 T 14-10-2018 Tharo_1328 34929098e97145363f386b4673c60910 427 Gene3D G3DSA:3.30.390.10 1 127 3.6E-57 T 14-10-2018 IPR029017 Enolase-like, N-terminal Tharo_1328 34929098e97145363f386b4673c60910 427 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 423 7.0E-127 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Tharo_1328 34929098e97145363f386b4673c60910 427 PRINTS PR00148 Enolase signature 311 322 1.2E-40 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Tharo_1328 34929098e97145363f386b4673c60910 427 PRINTS PR00148 Enolase signature 161 174 1.2E-40 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Tharo_1328 34929098e97145363f386b4673c60910 427 PRINTS PR00148 Enolase signature 363 380 1.2E-40 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Tharo_1328 34929098e97145363f386b4673c60910 427 PRINTS PR00148 Enolase signature 37 51 1.2E-40 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Tharo_1328 34929098e97145363f386b4673c60910 427 PRINTS PR00148 Enolase signature 334 348 1.2E-40 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Tharo_1328 34929098e97145363f386b4673c60910 427 PRINTS PR00148 Enolase signature 107 123 1.2E-40 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Tharo_1328 34929098e97145363f386b4673c60910 427 PIRSF PIRSF001400 1 425 5.4E-187 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Tharo_1328 34929098e97145363f386b4673c60910 427 Pfam PF03952 Enolase, N-terminal domain 4 133 6.2E-60 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Tharo_1328 34929098e97145363f386b4673c60910 427 Hamap MF_00318 Enolase [eno]. 2 411 43.87 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Tharo_1328 34929098e97145363f386b4673c60910 427 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 425 4.0E-205 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Tharo_1328 34929098e97145363f386b4673c60910 427 SUPERFAMILY SSF51604 139 426 3.4E-122 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Tharo_1779 063177352fecbcc3ec696f9ff9d33350 129 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 14 124 4.2E-28 T 14-10-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein Tharo_1779 063177352fecbcc3ec696f9ff9d33350 129 SUPERFAMILY SSF64076 1 124 1.01E-32 T 14-10-2018 IPR036748 MTH938-like superfamily Tharo_1779 063177352fecbcc3ec696f9ff9d33350 129 Gene3D G3DSA:3.40.1230.10 1 127 3.1E-33 T 14-10-2018 IPR036748 MTH938-like superfamily Tharo_0989 a4fc9d0762ffb9a3a588cf6eadcabe26 262 SMART SM00028 79 112 0.014 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Tharo_0989 a4fc9d0762ffb9a3a588cf6eadcabe26 262 SMART SM00028 45 78 82.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Tharo_0989 a4fc9d0762ffb9a3a588cf6eadcabe26 262 SMART SM00028 149 182 0.17 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Tharo_0989 a4fc9d0762ffb9a3a588cf6eadcabe26 262 SMART SM00028 183 216 73.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Tharo_0989 a4fc9d0762ffb9a3a588cf6eadcabe26 262 Pfam PF13432 Tetratricopeptide repeat 159 210 1.8E-5 T 14-10-2018 Tharo_0989 a4fc9d0762ffb9a3a588cf6eadcabe26 262 Pfam PF13432 Tetratricopeptide repeat 50 113 1.4E-7 T 14-10-2018 Tharo_0989 a4fc9d0762ffb9a3a588cf6eadcabe26 262 Gene3D G3DSA:1.25.40.10 40 260 5.2E-44 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_0989 a4fc9d0762ffb9a3a588cf6eadcabe26 262 TIGRFAM TIGR02521 type_IV_pilW: type IV pilus biogenesis/stability protein PilW 9 247 7.6E-61 T 14-10-2018 IPR013360 Pilus biogenesis/stability type IV, PilW Tharo_0989 a4fc9d0762ffb9a3a588cf6eadcabe26 262 SUPERFAMILY SSF81901 47 223 6.54E-18 T 14-10-2018 Tharo_0464 b81755c7da68cb2e602358d16ffe4b96 722 Pfam PF12838 4Fe-4S dicluster domain 589 635 4.4E-7 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_0464 b81755c7da68cb2e602358d16ffe4b96 722 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 224 235 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_0464 b81755c7da68cb2e602358d16ffe4b96 722 SUPERFAMILY SSF54862 319 706 2.6E-39 T 14-10-2018 Tharo_0464 b81755c7da68cb2e602358d16ffe4b96 722 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 621 632 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_0464 b81755c7da68cb2e602358d16ffe4b96 722 Gene3D G3DSA:3.30.70.20 202 285 1.8E-7 T 14-10-2018 Tharo_0464 b81755c7da68cb2e602358d16ffe4b96 722 Pfam PF00037 4Fe-4S binding domain 368 388 8.3E-6 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_0464 b81755c7da68cb2e602358d16ffe4b96 722 Pfam PF00037 4Fe-4S binding domain 219 239 8.3E-6 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_0464 b81755c7da68cb2e602358d16ffe4b96 722 Gene3D G3DSA:3.30.70.20 339 409 8.1E-11 T 14-10-2018 Tharo_0464 b81755c7da68cb2e602358d16ffe4b96 722 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 373 384 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_0464 b81755c7da68cb2e602358d16ffe4b96 722 SUPERFAMILY SSF54862 209 273 2.62E-13 T 14-10-2018 Tharo_0464 b81755c7da68cb2e602358d16ffe4b96 722 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 590 601 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_0464 b81755c7da68cb2e602358d16ffe4b96 722 Gene3D G3DSA:3.30.70.20 584 654 2.6E-10 T 14-10-2018 Tharo_2783 4a3cfb19741e15c79d427c935efed588 143 Pfam PF01982 Domain of unknown function DUF120 14 133 2.9E-26 T 14-10-2018 IPR023602 Riboflavin kinase domain, CTP-dependent GO:0016773 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 Tharo_2783 4a3cfb19741e15c79d427c935efed588 143 SUPERFAMILY SSF82114 8 133 1.01E-32 T 14-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 Tharo_2783 4a3cfb19741e15c79d427c935efed588 143 Gene3D G3DSA:2.40.30.30 7 139 3.9E-28 T 14-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 537 555 6.5E-38 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 599 613 6.5E-38 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 495 513 6.5E-38 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 566 584 6.5E-38 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 Gene3D G3DSA:1.10.1780.10 1 142 1.3E-42 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 Pfam PF07724 AAA domain (Cdc48 subfamily) 490 650 1.3E-46 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 SMART SM00382 210 355 5.5E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 SMART SM00382 491 640 8.6E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 215 347 1.6E-12 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 738 0.0 T 14-10-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0016887|GO:0043335 Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 Gene3D G3DSA:3.40.50.300 443 655 4.5E-78 T 14-10-2018 Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 Gene3D G3DSA:3.40.50.300 171 359 6.1E-68 T 14-10-2018 Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 SUPERFAMILY SSF52540 441 743 3.07E-76 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 Gene3D G3DSA:1.10.8.60 360 442 1.1E-32 T 14-10-2018 Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 Gene3D G3DSA:1.10.8.60 657 756 1.1E-27 T 14-10-2018 Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 522 540 - T 14-10-2018 IPR028299 ClpA/B, conserved site 2 Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 13 62 4.5E-15 T 14-10-2018 IPR004176 Clp, N-terminal Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 SMART SM01086 657 747 1.2E-33 T 14-10-2018 IPR019489 Clp ATPase, C-terminal Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 SUPERFAMILY SSF52540 172 422 8.14E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 306 318 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 657 737 2.7E-22 T 14-10-2018 IPR019489 Clp ATPase, C-terminal Tharo_2320 a622a69409c3a93ef6e8ff697232df9c 757 SUPERFAMILY SSF81923 1 141 5.76E-61 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 Tharo_1950 a190f91d0c1ec115be150678451124c1 188 Gene3D G3DSA:3.30.700.20 9 182 3.3E-46 T 14-10-2018 IPR027485 AMMECR1, N-terminal Tharo_1950 a190f91d0c1ec115be150678451124c1 188 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 7 185 3.4E-28 T 14-10-2018 IPR023473 AMMECR1 Tharo_1950 a190f91d0c1ec115be150678451124c1 188 SUPERFAMILY SSF143447 3 184 1.7E-52 T 14-10-2018 IPR036071 AMMECR1 domain superfamily Tharo_1950 a190f91d0c1ec115be150678451124c1 188 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 10 180 4.9E-53 T 14-10-2018 IPR027623 AmmeMemoRadiSam system protein A Tharo_1950 a190f91d0c1ec115be150678451124c1 188 Gene3D G3DSA:3.30.1490.150 108 180 3.3E-46 T 14-10-2018 Tharo_1950 a190f91d0c1ec115be150678451124c1 188 Pfam PF01871 AMMECR1 11 179 1.2E-40 T 14-10-2018 IPR002733 AMMECR1 domain Tharo_1485 e28668180f335f11732e014784b235a6 949 SMART SM00861 592 789 4.7E-58 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Tharo_1485 e28668180f335f11732e014784b235a6 949 Gene3D G3DSA:3.40.50.11610 726 934 3.9E-163 T 14-10-2018 Tharo_1485 e28668180f335f11732e014784b235a6 949 SUPERFAMILY SSF52518 117 544 1.37E-85 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_1485 e28668180f335f11732e014784b235a6 949 Pfam PF02779 Transketolase, pyrimidine binding domain 592 790 1.4E-62 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Tharo_1485 e28668180f335f11732e014784b235a6 949 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 794 937 1.8E-49 T 14-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 Tharo_1485 e28668180f335f11732e014784b235a6 949 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 12 936 0.0 T 14-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 Tharo_1485 e28668180f335f11732e014784b235a6 949 PIRSF PIRSF000157 1 939 0.0 T 14-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 Tharo_1485 e28668180f335f11732e014784b235a6 949 Gene3D G3DSA:3.40.50.970 164 518 3.5E-138 T 14-10-2018 Tharo_1485 e28668180f335f11732e014784b235a6 949 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 8 47 8.1E-17 T 14-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 Tharo_1485 e28668180f335f11732e014784b235a6 949 Gene3D G3DSA:1.10.287.1150 80 163 7.2E-25 T 14-10-2018 Tharo_1485 e28668180f335f11732e014784b235a6 949 Gene3D G3DSA:3.40.50.12470 555 805 3.9E-163 T 14-10-2018 Tharo_1485 e28668180f335f11732e014784b235a6 949 SUPERFAMILY SSF52518 575 796 6.08E-49 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_1485 e28668180f335f11732e014784b235a6 949 Pfam PF00676 Dehydrogenase E1 component 207 512 8.2E-47 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 Tharo_0853 4e341a0bc861a0dadacf3268549b1b27 291 Gene3D G3DSA:3.90.550.10 2 196 1.9E-29 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_0853 4e341a0bc861a0dadacf3268549b1b27 291 Pfam PF00535 Glycosyl transferase family 2 6 117 3.2E-25 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Tharo_0853 4e341a0bc861a0dadacf3268549b1b27 291 SUPERFAMILY SSF53448 11 197 2.25E-33 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_1728 710396552f53eca1f0c8f81d38076e4d 522 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 488 1.8E-257 T 14-10-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 Tharo_1728 710396552f53eca1f0c8f81d38076e4d 522 Gene3D G3DSA:1.10.3650.10 357 435 4.1E-28 T 14-10-2018 IPR038262 Nitrate reductase beta, C-terminal domain superfamily KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 Tharo_1728 710396552f53eca1f0c8f81d38076e4d 522 Pfam PF13247 4Fe-4S dicluster domain 175 269 6.2E-36 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_1728 710396552f53eca1f0c8f81d38076e4d 522 Gene3D G3DSA:3.30.70.20 1 311 1.3E-96 T 14-10-2018 Tharo_1728 710396552f53eca1f0c8f81d38076e4d 522 SUPERFAMILY SSF54862 1 487 3.66E-163 T 14-10-2018 Tharo_1728 710396552f53eca1f0c8f81d38076e4d 522 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 357 437 1.3E-28 T 14-10-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 Tharo_0034 4709f248544d62ae33d1f64a385443fc 460 PRINTS PR00145 Argininosuccinate lyase family signature 131 153 2.4E-7 T 14-10-2018 Tharo_0034 4709f248544d62ae33d1f64a385443fc 460 PRINTS PR00145 Argininosuccinate lyase family signature 173 193 2.4E-7 T 14-10-2018 Tharo_0034 4709f248544d62ae33d1f64a385443fc 460 PRINTS PR00145 Argininosuccinate lyase family signature 315 331 2.4E-7 T 14-10-2018 Tharo_0034 4709f248544d62ae33d1f64a385443fc 460 ProSitePatterns PS00163 Fumarate lyases signature. 315 324 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 Tharo_0034 4709f248544d62ae33d1f64a385443fc 460 Pfam PF10415 Fumarase C C-terminus 406 458 1.3E-24 T 14-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Tharo_0034 4709f248544d62ae33d1f64a385443fc 460 SUPERFAMILY SSF48557 2 459 1.57E-154 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 Tharo_0034 4709f248544d62ae33d1f64a385443fc 460 Gene3D G3DSA:1.10.40.30 406 460 5.1E-28 T 14-10-2018 Tharo_0034 4709f248544d62ae33d1f64a385443fc 460 PRINTS PR00149 Fumarate lyase superfamily signature 269 296 6.7E-34 T 14-10-2018 IPR000362 Fumarate lyase family Tharo_0034 4709f248544d62ae33d1f64a385443fc 460 PRINTS PR00149 Fumarate lyase superfamily signature 132 150 6.7E-34 T 14-10-2018 IPR000362 Fumarate lyase family Tharo_0034 4709f248544d62ae33d1f64a385443fc 460 PRINTS PR00149 Fumarate lyase superfamily signature 178 196 6.7E-34 T 14-10-2018 IPR000362 Fumarate lyase family Tharo_0034 4709f248544d62ae33d1f64a385443fc 460 PRINTS PR00149 Fumarate lyase superfamily signature 315 331 6.7E-34 T 14-10-2018 IPR000362 Fumarate lyase family Tharo_0034 4709f248544d62ae33d1f64a385443fc 460 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 3 459 8.0E-214 T 14-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Tharo_0034 4709f248544d62ae33d1f64a385443fc 460 Gene3D G3DSA:1.20.200.10 137 405 2.6E-116 T 14-10-2018 Tharo_0034 4709f248544d62ae33d1f64a385443fc 460 Gene3D G3DSA:1.10.275.10 3 136 8.6E-55 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal Tharo_0034 4709f248544d62ae33d1f64a385443fc 460 Pfam PF00206 Lyase 10 340 3.6E-105 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal Tharo_0034 4709f248544d62ae33d1f64a385443fc 460 Hamap MF_00743 Fumarate hydratase class II [fumC]. 2 460 87.482 T 14-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Tharo_0671 e44d4bc7b48d590054027418cc241550 250 Gene3D G3DSA:3.40.50.720 1 250 7.6E-77 T 14-10-2018 Tharo_0671 e44d4bc7b48d590054027418cc241550 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Tharo_0671 e44d4bc7b48d590054027418cc241550 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 248 3.2E-66 T 14-10-2018 Tharo_0671 e44d4bc7b48d590054027418cc241550 250 SUPERFAMILY SSF51735 1 249 4.65E-78 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_0671 e44d4bc7b48d590054027418cc241550 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.1E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0671 e44d4bc7b48d590054027418cc241550 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.1E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0671 e44d4bc7b48d590054027418cc241550 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.1E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0671 e44d4bc7b48d590054027418cc241550 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.9E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0671 e44d4bc7b48d590054027418cc241550 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.9E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0671 e44d4bc7b48d590054027418cc241550 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.9E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0671 e44d4bc7b48d590054027418cc241550 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.9E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0671 e44d4bc7b48d590054027418cc241550 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.9E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0671 e44d4bc7b48d590054027418cc241550 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 3.9E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2322 0364ef69a315e03d1ea78ed4d863ba4f 437 SUPERFAMILY SSF51621 6 436 3.72E-151 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Tharo_2322 0364ef69a315e03d1ea78ed4d863ba4f 437 Pfam PF00463 Isocitrate lyase family 258 436 1.1E-50 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 Tharo_2322 0364ef69a315e03d1ea78ed4d863ba4f 437 Pfam PF00463 Isocitrate lyase family 14 257 3.8E-60 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 Tharo_2322 0364ef69a315e03d1ea78ed4d863ba4f 437 Gene3D G3DSA:3.20.20.60 1 419 3.6E-178 T 14-10-2018 Tharo_2322 0364ef69a315e03d1ea78ed4d863ba4f 437 PIRSF PIRSF001362 1 437 2.0E-214 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 Tharo_2322 0364ef69a315e03d1ea78ed4d863ba4f 437 ProSitePatterns PS00161 Isocitrate lyase signature. 195 200 - T 14-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 Tharo_2322 0364ef69a315e03d1ea78ed4d863ba4f 437 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 10 257 2.3E-107 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 Tharo_2322 0364ef69a315e03d1ea78ed4d863ba4f 437 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 258 436 7.2E-84 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 Tharo_3369 ac09f0ea3eb08e3fc1238ea1056b7421 381 Gene3D G3DSA:3.50.50.60 3 331 8.5E-115 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_3369 ac09f0ea3eb08e3fc1238ea1056b7421 381 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 36 5.3E-6 T 14-10-2018 Tharo_3369 ac09f0ea3eb08e3fc1238ea1056b7421 381 Gene3D G3DSA:3.30.9.20 40 247 8.5E-115 T 14-10-2018 Tharo_3369 ac09f0ea3eb08e3fc1238ea1056b7421 381 Pfam PF01494 FAD binding domain 129 295 3.3E-5 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 Tharo_3369 ac09f0ea3eb08e3fc1238ea1056b7421 381 SUPERFAMILY SSF51905 5 342 3.67E-38 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_3369 ac09f0ea3eb08e3fc1238ea1056b7421 381 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 2.8E-7 T 14-10-2018 Tharo_3369 ac09f0ea3eb08e3fc1238ea1056b7421 381 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 128 143 2.8E-7 T 14-10-2018 Tharo_3369 ac09f0ea3eb08e3fc1238ea1056b7421 381 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 273 289 2.8E-7 T 14-10-2018 Tharo_1601 1658ff0564743befb39b260db2dabe02 321 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 232 320 4.7E-36 T 14-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Tharo_1601 1658ff0564743befb39b260db2dabe02 321 SUPERFAMILY SSF53901 4 319 4.81E-71 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_1601 1658ff0564743befb39b260db2dabe02 321 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 109 186 1.7E-33 T 14-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Tharo_1601 1658ff0564743befb39b260db2dabe02 321 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 3 320 3.6E-120 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Tharo_1601 1658ff0564743befb39b260db2dabe02 321 Gene3D G3DSA:3.40.47.10 1 321 1.3E-130 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_1601 1658ff0564743befb39b260db2dabe02 321 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 321 69.215 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Tharo_2856 e16e3be629c902eacd3b21756e00e739 713 SUPERFAMILY SSF56784 388 692 2.47E-46 T 14-10-2018 IPR036412 HAD-like superfamily Tharo_2856 e16e3be629c902eacd3b21756e00e739 713 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 149 694 1.1E-140 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Tharo_2856 e16e3be629c902eacd3b21756e00e739 713 Gene3D G3DSA:3.40.1110.10 401 524 2.2E-74 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Tharo_2856 e16e3be629c902eacd3b21756e00e739 713 Pfam PF00702 haloacid dehalogenase-like hydrolase 387 606 1.3E-29 T 14-10-2018 Tharo_2856 e16e3be629c902eacd3b21756e00e739 713 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 171 672 7.3E-64 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Tharo_2856 e16e3be629c902eacd3b21756e00e739 713 ProSitePatterns PS01229 Hypothetical cof family signature 2. 593 615 - T 14-10-2018 Tharo_2856 e16e3be629c902eacd3b21756e00e739 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 593 612 4.7E-24 T 14-10-2018 Tharo_2856 e16e3be629c902eacd3b21756e00e739 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 616 628 4.7E-24 T 14-10-2018 Tharo_2856 e16e3be629c902eacd3b21756e00e739 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 248 262 4.7E-24 T 14-10-2018 Tharo_2856 e16e3be629c902eacd3b21756e00e739 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 390 404 4.7E-24 T 14-10-2018 Tharo_2856 e16e3be629c902eacd3b21756e00e739 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 517 528 4.7E-24 T 14-10-2018 Tharo_2856 e16e3be629c902eacd3b21756e00e739 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 540 550 4.7E-24 T 14-10-2018 Tharo_2856 e16e3be629c902eacd3b21756e00e739 713 Gene3D G3DSA:2.70.150.20 191 302 2.4E-27 T 14-10-2018 Tharo_2856 e16e3be629c902eacd3b21756e00e739 713 Pfam PF00122 E1-E2 ATPase 203 368 1.0E-32 T 14-10-2018 Tharo_2856 e16e3be629c902eacd3b21756e00e739 713 SUPERFAMILY SSF81653 203 298 1.44E-22 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Tharo_2856 e16e3be629c902eacd3b21756e00e739 713 Gene3D G3DSA:3.40.50.1000 371 645 2.2E-74 T 14-10-2018 IPR023214 HAD superfamily Tharo_2856 e16e3be629c902eacd3b21756e00e739 713 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 392 398 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Tharo_2824 4ba0356e5c4a160bbb1f6d399e88c6b3 485 PIRSF PIRSF006247 1 485 2.1E-163 T 14-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 Tharo_2824 4ba0356e5c4a160bbb1f6d399e88c6b3 485 Pfam PF02386 Cation transport protein 44 477 6.5E-65 T 14-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 Tharo_0266 a2aae45005d6a69fc0c093d1b1abc7fb 660 Pfam PF01578 Cytochrome C assembly protein 89 295 7.3E-52 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 Tharo_0266 a2aae45005d6a69fc0c093d1b1abc7fb 660 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 54 641 1.5E-223 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_0266 a2aae45005d6a69fc0c093d1b1abc7fb 660 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 313 328 1.4E-59 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_0266 a2aae45005d6a69fc0c093d1b1abc7fb 660 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 351 368 1.4E-59 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_0266 a2aae45005d6a69fc0c093d1b1abc7fb 660 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 1.4E-59 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_0266 a2aae45005d6a69fc0c093d1b1abc7fb 660 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 394 413 1.4E-59 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_0266 a2aae45005d6a69fc0c093d1b1abc7fb 660 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 1.4E-59 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_0266 a2aae45005d6a69fc0c093d1b1abc7fb 660 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 631 644 1.4E-59 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_0266 a2aae45005d6a69fc0c093d1b1abc7fb 660 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 189 204 1.4E-59 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_0266 a2aae45005d6a69fc0c093d1b1abc7fb 660 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 315 638 7.3E-129 T 14-10-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal Tharo_0266 a2aae45005d6a69fc0c093d1b1abc7fb 660 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 1.6E-90 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_0266 a2aae45005d6a69fc0c093d1b1abc7fb 660 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 210 236 1.6E-90 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_0266 a2aae45005d6a69fc0c093d1b1abc7fb 660 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 294 310 1.6E-90 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_0266 a2aae45005d6a69fc0c093d1b1abc7fb 660 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 274 294 1.6E-90 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_0266 a2aae45005d6a69fc0c093d1b1abc7fb 660 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 159 181 1.6E-90 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_0266 a2aae45005d6a69fc0c093d1b1abc7fb 660 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 1.6E-90 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_0266 a2aae45005d6a69fc0c093d1b1abc7fb 660 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 244 264 1.6E-90 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_0266 a2aae45005d6a69fc0c093d1b1abc7fb 660 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 310 329 1.6E-90 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_1064 7e06e41d91b3b4066c099617466fc390 426 Gene3D G3DSA:3.10.580.10 188 337 2.4E-37 T 14-10-2018 Tharo_1064 7e06e41d91b3b4066c099617466fc390 426 Pfam PF01595 Domain of unknown function DUF21 11 185 4.2E-41 T 14-10-2018 IPR002550 CNNM, transmembrane domain Tharo_1064 7e06e41d91b3b4066c099617466fc390 426 SMART SM01091 342 420 1.3E-22 T 14-10-2018 IPR005170 Transporter-associated domain Tharo_1064 7e06e41d91b3b4066c099617466fc390 426 SUPERFAMILY SSF56176 344 419 1.64E-19 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Tharo_1064 7e06e41d91b3b4066c099617466fc390 426 SUPERFAMILY SSF54631 195 329 5.37E-26 T 14-10-2018 Tharo_1064 7e06e41d91b3b4066c099617466fc390 426 Pfam PF00571 CBS domain 279 326 1.4E-7 T 14-10-2018 IPR000644 CBS domain Tharo_1064 7e06e41d91b3b4066c099617466fc390 426 Gene3D G3DSA:3.30.465.10 342 418 5.1E-25 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Tharo_1064 7e06e41d91b3b4066c099617466fc390 426 Pfam PF03471 Transporter associated domain 344 416 3.8E-17 T 14-10-2018 IPR005170 Transporter-associated domain Tharo_0574 5ae21763cb8d02d8a926bd0327ab0e07 1286 Pfam PF11907 Domain of unknown function (DUF3427) 1152 1273 2.3E-18 T 14-10-2018 IPR021835 Protein of unknown function DUF3427 Tharo_0574 5ae21763cb8d02d8a926bd0327ab0e07 1286 SUPERFAMILY SSF51306 1011 1142 8.37E-10 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily Tharo_0574 5ae21763cb8d02d8a926bd0327ab0e07 1286 SMART SM00490 641 721 9.0E-8 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_0574 5ae21763cb8d02d8a926bd0327ab0e07 1286 Gene3D G3DSA:3.30.870.10 208 378 1.0E-21 T 14-10-2018 Tharo_0574 5ae21763cb8d02d8a926bd0327ab0e07 1286 SMART SM00487 395 581 2.6E-19 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Tharo_0574 5ae21763cb8d02d8a926bd0327ab0e07 1286 Gene3D G3DSA:3.40.50.150 2 198 4.8E-51 T 14-10-2018 Tharo_0574 5ae21763cb8d02d8a926bd0327ab0e07 1286 SUPERFAMILY SSF56024 210 343 5.02E-6 T 14-10-2018 Tharo_0574 5ae21763cb8d02d8a926bd0327ab0e07 1286 Pfam PF04851 Type III restriction enzyme, res subunit 399 546 5.7E-28 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 Tharo_0574 5ae21763cb8d02d8a926bd0327ab0e07 1286 SUPERFAMILY SSF52540 445 736 1.16E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0574 5ae21763cb8d02d8a926bd0327ab0e07 1286 Gene3D G3DSA:3.40.50.300 566 749 5.7E-34 T 14-10-2018 Tharo_0574 5ae21763cb8d02d8a926bd0327ab0e07 1286 Gene3D G3DSA:2.10.109.10 1018 1150 1.2E-7 T 14-10-2018 Tharo_0574 5ae21763cb8d02d8a926bd0327ab0e07 1286 Gene3D G3DSA:3.40.50.300 386 562 2.0E-41 T 14-10-2018 Tharo_0574 5ae21763cb8d02d8a926bd0327ab0e07 1286 Pfam PF13649 Methyltransferase domain 41 129 2.4E-9 T 14-10-2018 Tharo_0574 5ae21763cb8d02d8a926bd0327ab0e07 1286 SUPERFAMILY SSF53335 7 163 3.35E-23 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_0574 5ae21763cb8d02d8a926bd0327ab0e07 1286 Pfam PF13091 PLD-like domain 215 360 4.1E-12 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 Tharo_0574 5ae21763cb8d02d8a926bd0327ab0e07 1286 Pfam PF00271 Helicase conserved C-terminal domain 620 719 6.1E-9 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_0814 7e1dc9fb0ef151230567dd9089913b14 275 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 17 254 1.1E-27 T 14-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Tharo_0814 7e1dc9fb0ef151230567dd9089913b14 275 Gene3D G3DSA:3.20.20.70 1 274 3.8E-99 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_0814 7e1dc9fb0ef151230567dd9089913b14 275 SMART SM00934 17 260 7.7E-50 T 14-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Tharo_0814 7e1dc9fb0ef151230567dd9089913b14 275 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 90 103 - T 14-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Tharo_0814 7e1dc9fb0ef151230567dd9089913b14 275 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 2 273 35.401 T 14-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_0814 7e1dc9fb0ef151230567dd9089913b14 275 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 3 260 6.0E-72 T 14-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_0814 7e1dc9fb0ef151230567dd9089913b14 275 SUPERFAMILY SSF51366 2 268 6.0E-75 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Tharo_1382 d771aa4b51631b2597d817a473d05285 85 Gene3D G3DSA:1.10.1220.10 10 59 4.4E-22 T 14-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 Tharo_1382 d771aa4b51631b2597d817a473d05285 85 SUPERFAMILY SSF47598 3 64 3.69E-19 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Tharo_0065 5364b5c221dd5a1967a6b61bc86e6cdf 153 PIRSF PIRSF000027 10 153 1.9E-30 T 14-10-2018 IPR012127 Cytochrome c prime GO:0005506|GO:0009055|GO:0020037|GO:0042597 Tharo_0065 5364b5c221dd5a1967a6b61bc86e6cdf 153 SUPERFAMILY SSF47175 25 152 1.62E-38 T 14-10-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 Tharo_0065 5364b5c221dd5a1967a6b61bc86e6cdf 153 PRINTS PR00608 Class II cytochrome C signature 117 140 4.9E-9 T 14-10-2018 IPR015984 Cytochrome c prime, subgroup Tharo_0065 5364b5c221dd5a1967a6b61bc86e6cdf 153 PRINTS PR00608 Class II cytochrome C signature 140 151 4.9E-9 T 14-10-2018 IPR015984 Cytochrome c prime, subgroup Tharo_0065 5364b5c221dd5a1967a6b61bc86e6cdf 153 Pfam PF01322 Cytochrome C' 29 151 1.8E-34 T 14-10-2018 IPR002321 Cytochrome c, class II GO:0005506|GO:0009055|GO:0020037 Tharo_0065 5364b5c221dd5a1967a6b61bc86e6cdf 153 Gene3D G3DSA:1.20.120.10 23 152 3.8E-35 T 14-10-2018 Tharo_0801 2debe08d09a0788db29d22b910ca7646 222 PIRSF PIRSF006102 2 211 1.1E-65 T 14-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 Tharo_0801 2debe08d09a0788db29d22b910ca7646 222 Pfam PF02508 Rnf-Nqr subunit, membrane protein 7 194 1.6E-59 T 14-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 Tharo_0801 2debe08d09a0788db29d22b910ca7646 222 TIGRFAM TIGR01939 nqrD: NADH:ubiquinone oxidoreductase, Na(+)-translocating, D subunit 2 206 1.9E-102 T 14-10-2018 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 Tharo_0801 2debe08d09a0788db29d22b910ca7646 222 Hamap MF_00428 Na(+)-translocating NADH-quinone reductase subunit D [nqrD]. 1 206 35.738 T 14-10-2018 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 Tharo_0785 1a4dae785a44e44bb8446b06df3369e6 256 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 53 227 3.7E-42 T 14-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 Tharo_0785 1a4dae785a44e44bb8446b06df3369e6 256 PIRSF PIRSF000857 9 256 2.8E-79 T 14-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 Tharo_0785 1a4dae785a44e44bb8446b06df3369e6 256 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 58 251 4.8E-76 T 14-10-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 Tharo_0785 1a4dae785a44e44bb8446b06df3369e6 256 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 44 252 2.8E-49 T 14-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 Tharo_0785 1a4dae785a44e44bb8446b06df3369e6 256 SUPERFAMILY SSF52402 31 214 1.15E-47 T 14-10-2018 Tharo_0785 1a4dae785a44e44bb8446b06df3369e6 256 Gene3D G3DSA:3.40.50.620 19 255 1.5E-66 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_2873 07104d73828b63c50363da64615aad59 178 Gene3D G3DSA:3.60.20.10 2 178 1.9E-66 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Tharo_2873 07104d73828b63c50363da64615aad59 178 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 177 41.175 T 14-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 Tharo_2873 07104d73828b63c50363da64615aad59 178 Pfam PF00227 Proteasome subunit 5 176 1.0E-21 T 14-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 Tharo_2873 07104d73828b63c50363da64615aad59 178 SUPERFAMILY SSF56235 3 177 8.96E-58 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Tharo_2873 07104d73828b63c50363da64615aad59 178 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 176 1.5E-84 T 14-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 Tharo_2873 07104d73828b63c50363da64615aad59 178 PIRSF PIRSF039093 1 178 4.4E-86 T 14-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 Tharo_1209 011bdf657aae9d3aa45c656315019f35 295 Gene3D G3DSA:1.10.3660.10 181 287 1.2E-34 T 14-10-2018 Tharo_1209 011bdf657aae9d3aa45c656315019f35 295 Gene3D G3DSA:3.40.50.720 5 180 3.4E-53 T 14-10-2018 Tharo_1209 011bdf657aae9d3aa45c656315019f35 295 SUPERFAMILY SSF48179 177 285 6.12E-34 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Tharo_1209 011bdf657aae9d3aa45c656315019f35 295 SUPERFAMILY SSF51735 6 173 3.63E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1209 011bdf657aae9d3aa45c656315019f35 295 Pfam PF02153 Prephenate dehydrogenase 19 275 1.2E-71 T 14-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 Tharo_0434 a3ab4ddfd67c19288ad08906f5b9c63a 179 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 11 160 1.9E-54 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Tharo_0434 a3ab4ddfd67c19288ad08906f5b9c63a 179 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 120 154 - T 14-10-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 Tharo_0434 a3ab4ddfd67c19288ad08906f5b9c63a 179 Gene3D G3DSA:3.30.420.10 11 162 2.9E-47 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_0434 a3ab4ddfd67c19288ad08906f5b9c63a 179 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 11 157 4.4E-54 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Tharo_0434 a3ab4ddfd67c19288ad08906f5b9c63a 179 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 12 25 5.7E-33 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Tharo_0434 a3ab4ddfd67c19288ad08906f5b9c63a 179 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 68 84 5.7E-33 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Tharo_0434 a3ab4ddfd67c19288ad08906f5b9c63a 179 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 90 106 5.7E-33 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Tharo_0434 a3ab4ddfd67c19288ad08906f5b9c63a 179 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 114 133 5.7E-33 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Tharo_0434 a3ab4ddfd67c19288ad08906f5b9c63a 179 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 145 157 5.7E-33 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Tharo_0434 a3ab4ddfd67c19288ad08906f5b9c63a 179 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 9 160 46.672 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Tharo_0434 a3ab4ddfd67c19288ad08906f5b9c63a 179 SUPERFAMILY SSF53098 10 161 8.09E-53 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_2978 a14d7bdb7da7120aed2e04719a2ae31f 432 Gene3D G3DSA:3.30.460.10 1 122 3.5E-27 T 14-10-2018 Tharo_2978 a14d7bdb7da7120aed2e04719a2ae31f 432 Hamap MF_01262 CCA-adding enzyme [cca]. 1 402 39.726 T 14-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 Tharo_2978 a14d7bdb7da7120aed2e04719a2ae31f 432 Hamap MF_01261 Multifunctional CCA protein [cca]. 1 408 50.551 T 14-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 Tharo_2978 a14d7bdb7da7120aed2e04719a2ae31f 432 Pfam PF01966 HD domain 227 304 4.8E-9 T 14-10-2018 IPR006674 HD domain Tharo_2978 a14d7bdb7da7120aed2e04719a2ae31f 432 SUPERFAMILY SSF81301 1 118 8.83E-31 T 14-10-2018 Tharo_2978 a14d7bdb7da7120aed2e04719a2ae31f 432 Pfam PF01743 Poly A polymerase head domain 3 121 6.4E-17 T 14-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 Tharo_2978 a14d7bdb7da7120aed2e04719a2ae31f 432 PIRSF PIRSF000813 1 409 4.3E-181 T 14-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 Tharo_2978 a14d7bdb7da7120aed2e04719a2ae31f 432 SMART SM00471 222 336 9.6E-5 T 14-10-2018 IPR003607 HD/PDEase domain Tharo_2978 a14d7bdb7da7120aed2e04719a2ae31f 432 Gene3D G3DSA:1.10.3090.10 123 354 1.2E-35 T 14-10-2018 Tharo_2978 a14d7bdb7da7120aed2e04719a2ae31f 432 SUPERFAMILY SSF81891 121 354 1.83E-47 T 14-10-2018 Tharo_2978 a14d7bdb7da7120aed2e04719a2ae31f 432 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 148 210 1.3E-12 T 14-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 Tharo_2654 83352fea0739477c8f1511a5ed126ba0 120 Pfam PF13518 Helix-turn-helix domain 14 67 3.6E-6 T 14-10-2018 Tharo_0207 83352fea0739477c8f1511a5ed126ba0 120 Pfam PF13518 Helix-turn-helix domain 14 67 3.6E-6 T 14-10-2018 Tharo_0227 83352fea0739477c8f1511a5ed126ba0 120 Pfam PF13518 Helix-turn-helix domain 14 67 3.6E-6 T 14-10-2018 Tharo_0159 83352fea0739477c8f1511a5ed126ba0 120 Pfam PF13518 Helix-turn-helix domain 14 67 3.6E-6 T 14-10-2018 Tharo_0594 83352fea0739477c8f1511a5ed126ba0 120 Pfam PF13518 Helix-turn-helix domain 14 67 3.6E-6 T 14-10-2018 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 SMART SM01096 419 542 8.9E-76 T 14-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 SUPERFAMILY SSF52440 1 127 1.73E-50 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 704 718 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 SUPERFAMILY SSF56059 128 401 3.54E-110 T 14-10-2018 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 Gene3D G3DSA:1.10.1030.10 403 548 9.1E-48 T 14-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 668 873 1.9E-35 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 3.6E-73 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 Gene3D G3DSA:3.40.50.1380 935 1073 2.6E-38 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 Gene3D G3DSA:3.40.50.20 1 116 3.0E-50 T 14-10-2018 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 Gene3D G3DSA:3.40.50.20 549 657 1.5E-48 T 14-10-2018 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 SUPERFAMILY SSF56059 668 932 2.12E-103 T 14-10-2018 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 422 542 4.4E-40 T 14-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 SUPERFAMILY SSF48108 396 549 1.83E-52 T 14-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 Gene3D G3DSA:3.30.470.20 660 934 1.1E-118 T 14-10-2018 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 8.8E-66 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 380 398 8.8E-66 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 8.8E-66 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 8.8E-66 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 8.8E-66 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 8.8E-66 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 8.8E-66 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 Pfam PF02142 MGS-like domain 955 1040 3.0E-21 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 SUPERFAMILY SSF52440 551 670 1.73E-49 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1050 0.0 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 SUPERFAMILY SSF52335 934 1071 1.96E-37 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1068 13.404 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 Gene3D G3DSA:3.30.470.20 119 402 2.7E-130 T 14-10-2018 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 837 844 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 SMART SM00851 954 1041 5.0E-32 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Tharo_1893 acc2190b93685fc11407fce68fa31696 1076 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1062 13.243 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 5 476 1.4E-160 T 14-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 Gene3D G3DSA:3.30.390.30 356 476 2.8E-46 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 Gene3D G3DSA:3.50.50.60 6 343 4.4E-112 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 SUPERFAMILY SSF55424 353 475 5.33E-41 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 159 4.0E-80 T 14-10-2018 Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 289 4.0E-80 T 14-10-2018 Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 318 325 4.0E-80 T 14-10-2018 Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 418 433 4.0E-80 T 14-10-2018 Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 4.0E-80 T 14-10-2018 Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 353 374 4.0E-80 T 14-10-2018 Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 440 460 4.0E-80 T 14-10-2018 Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 186 211 4.0E-80 T 14-10-2018 Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 48 63 4.0E-80 T 14-10-2018 Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 49 59 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 Gene3D G3DSA:3.50.50.60 166 288 4.4E-112 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 338 2.2E-71 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 PIRSF PIRSF000350 1 472 7.7E-83 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 357 466 3.8E-37 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 SUPERFAMILY SSF51905 2 348 3.05E-63 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 8.0E-44 T 14-10-2018 Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 290 8.0E-44 T 14-10-2018 Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 303 325 8.0E-44 T 14-10-2018 Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 8.0E-44 T 14-10-2018 Tharo_1487 e298199061a867fc5fecc5b2c9c5f6e6 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 186 204 8.0E-44 T 14-10-2018 Tharo_1810 1c54a366be32c0a4467f6eb16cbff0b8 286 Gene3D G3DSA:3.40.50.150 46 255 8.8E-49 T 14-10-2018 Tharo_1810 1c54a366be32c0a4467f6eb16cbff0b8 286 Pfam PF01564 Spermine/spermidine synthase domain 88 198 3.5E-6 T 14-10-2018 Tharo_1810 1c54a366be32c0a4467f6eb16cbff0b8 286 SUPERFAMILY SSF53335 38 242 2.09E-41 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_2467 2c7e044acb7e8be7705367c32e6e8820 259 Pfam PF13614 AAA domain 5 182 1.8E-39 T 14-10-2018 IPR025669 AAA domain Tharo_2467 2c7e044acb7e8be7705367c32e6e8820 259 Gene3D G3DSA:3.40.50.300 3 258 1.1E-65 T 14-10-2018 Tharo_2467 2c7e044acb7e8be7705367c32e6e8820 259 SUPERFAMILY SSF52540 1 256 1.22E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1567 d43f86b440f30c5de412c4c517266857 340 SUPERFAMILY SSF51395 10 319 8.42E-90 T 14-10-2018 Tharo_1567 d43f86b440f30c5de412c4c517266857 340 Gene3D G3DSA:1.10.1200.80 253 332 3.6E-12 T 14-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 Tharo_1567 d43f86b440f30c5de412c4c517266857 340 PIRSF PIRSF006621 1 327 1.2E-105 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 Tharo_1567 d43f86b440f30c5de412c4c517266857 340 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 1 322 49.434 T 14-10-2018 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 Tharo_1567 d43f86b440f30c5de412c4c517266857 340 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 6 320 5.4E-124 T 14-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 Tharo_1567 d43f86b440f30c5de412c4c517266857 340 Pfam PF01207 Dihydrouridine synthase (Dus) 13 313 9.6E-107 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 Tharo_1567 d43f86b440f30c5de412c4c517266857 340 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 14-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 Tharo_1567 d43f86b440f30c5de412c4c517266857 340 Gene3D G3DSA:3.20.20.70 7 250 3.5E-80 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_2994 5be5b24cfb2e49a1005df6f9c6640bb6 185 Gene3D G3DSA:3.40.50.2020 3 185 1.1E-47 T 14-10-2018 Tharo_2994 5be5b24cfb2e49a1005df6f9c6640bb6 185 SUPERFAMILY SSF53271 13 183 1.17E-40 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Tharo_2994 5be5b24cfb2e49a1005df6f9c6640bb6 185 Pfam PF00156 Phosphoribosyl transferase domain 22 144 5.8E-20 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Tharo_0702 0bccac42a6ce509a5ca807c6489c5921 112 TIGRFAM TIGR03750 conj_TIGR03750: conjugative transfer region protein, TIGR03750 family 1 105 2.9E-35 T 14-10-2018 IPR021877 Protein of unknown function DUF3487 Tharo_0702 0bccac42a6ce509a5ca807c6489c5921 112 Pfam PF11990 Protein of unknown function (DUF3487) 1 105 9.5E-33 T 14-10-2018 IPR021877 Protein of unknown function DUF3487 Tharo_2744 f7dfbafca67b8f7094cfe055a4351569 209 Gene3D G3DSA:3.40.50.2300 1 127 5.8E-29 T 14-10-2018 Tharo_2744 f7dfbafca67b8f7094cfe055a4351569 209 SMART SM00448 2 116 5.9E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2744 f7dfbafca67b8f7094cfe055a4351569 209 Gene3D G3DSA:1.10.10.10 145 208 2.1E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2744 f7dfbafca67b8f7094cfe055a4351569 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 3.3E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2744 f7dfbafca67b8f7094cfe055a4351569 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 3.3E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2744 f7dfbafca67b8f7094cfe055a4351569 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 3.3E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2744 f7dfbafca67b8f7094cfe055a4351569 209 SMART SM00421 145 202 2.9E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2744 f7dfbafca67b8f7094cfe055a4351569 209 Pfam PF00072 Response regulator receiver domain 4 116 4.2E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2744 f7dfbafca67b8f7094cfe055a4351569 209 SUPERFAMILY SSF52172 1 123 3.98E-29 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_2744 f7dfbafca67b8f7094cfe055a4351569 209 SUPERFAMILY SSF46894 141 206 3.74E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_2744 f7dfbafca67b8f7094cfe055a4351569 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 201 7.3E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2475 5f09b7be2cca7a4691e6f143f8f1b7ce 439 PIRSF PIRSF000151 13 439 3.6E-173 T 14-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 Tharo_2475 5f09b7be2cca7a4691e6f143f8f1b7ce 439 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 20 438 41.858 T 14-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Tharo_2475 5f09b7be2cca7a4691e6f143f8f1b7ce 439 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 28 428 2.3E-146 T 14-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Tharo_2475 5f09b7be2cca7a4691e6f143f8f1b7ce 439 SUPERFAMILY SSF53720 20 438 6.68E-117 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Tharo_2475 5f09b7be2cca7a4691e6f143f8f1b7ce 439 Gene3D G3DSA:3.40.309.10 241 396 2.2E-165 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Tharo_2475 5f09b7be2cca7a4691e6f143f8f1b7ce 439 Gene3D G3DSA:3.40.605.10 27 435 2.2E-165 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Tharo_2475 5f09b7be2cca7a4691e6f143f8f1b7ce 439 Pfam PF00171 Aldehyde dehydrogenase family 331 395 9.3E-10 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Tharo_2475 5f09b7be2cca7a4691e6f143f8f1b7ce 439 Pfam PF00171 Aldehyde dehydrogenase family 26 290 8.9E-13 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Tharo_3084 8c840e459df9591d024be22393e1af50 406 Gene3D G3DSA:1.10.540.10 1 134 8.2E-24 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Tharo_3084 8c840e459df9591d024be22393e1af50 406 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 137 231 1.4E-17 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Tharo_3084 8c840e459df9591d024be22393e1af50 406 Gene3D G3DSA:2.40.110.10 136 251 2.0E-30 T 14-10-2018 Tharo_3084 8c840e459df9591d024be22393e1af50 406 SUPERFAMILY SSF47203 242 395 6.44E-40 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Tharo_3084 8c840e459df9591d024be22393e1af50 406 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 251 393 3.3E-32 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Tharo_3084 8c840e459df9591d024be22393e1af50 406 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 133 4.1E-18 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Tharo_3084 8c840e459df9591d024be22393e1af50 406 Gene3D G3DSA:1.20.140.10 252 395 1.4E-36 T 14-10-2018 Tharo_3084 8c840e459df9591d024be22393e1af50 406 SUPERFAMILY SSF56645 1 242 4.84E-52 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Tharo_0141 845f39650f46fbfc1418c5037838a760 366 Gene3D G3DSA:2.40.40.10 122 215 5.0E-36 T 14-10-2018 IPR036908 RlpA-like domain superfamily Tharo_0141 845f39650f46fbfc1418c5037838a760 366 SUPERFAMILY SSF110997 289 364 5.23E-8 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 Tharo_0141 845f39650f46fbfc1418c5037838a760 366 Pfam PF03330 Lytic transglycolase 123 212 3.4E-26 T 14-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain Tharo_0141 845f39650f46fbfc1418c5037838a760 366 Pfam PF05036 Sporulation related domain 289 363 4.8E-8 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 Tharo_0141 845f39650f46fbfc1418c5037838a760 366 SUPERFAMILY SSF50685 127 209 4.88E-10 T 14-10-2018 IPR036908 RlpA-like domain superfamily Tharo_0141 845f39650f46fbfc1418c5037838a760 366 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 125 215 5.6E-39 T 14-10-2018 IPR012997 Rare lipoprotein A Tharo_0141 845f39650f46fbfc1418c5037838a760 366 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 11 215 25.51 T 14-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 Tharo_1798 5219005a2560721d02b5441fd2d69c7f 248 Gene3D G3DSA:3.40.50.300 24 248 8.0E-68 T 14-10-2018 Tharo_1798 5219005a2560721d02b5441fd2d69c7f 248 Pfam PF00005 ABC transporter 46 192 3.6E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_1798 5219005a2560721d02b5441fd2d69c7f 248 SUPERFAMILY SSF52540 38 246 1.13E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1798 5219005a2560721d02b5441fd2d69c7f 248 SMART SM00382 55 244 2.6E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1798 5219005a2560721d02b5441fd2d69c7f 248 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_2737 cef0e7bf575bc2f791507542c63b6d07 115 Gene3D G3DSA:1.20.5.1030 54 111 7.2E-16 T 14-10-2018 IPR038379 SecE superfamily Tharo_2737 cef0e7bf575bc2f791507542c63b6d07 115 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 58 107 5.7E-19 T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Tharo_2737 cef0e7bf575bc2f791507542c63b6d07 115 Hamap MF_00422 Protein translocase subunit SecE [secE]. 54 111 11.837 T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Tharo_2737 cef0e7bf575bc2f791507542c63b6d07 115 PRINTS PR01650 Bacterial translocase SecE signature 53 73 8.4E-15 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 Tharo_2737 cef0e7bf575bc2f791507542c63b6d07 115 PRINTS PR01650 Bacterial translocase SecE signature 32 53 8.4E-15 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 Tharo_2737 cef0e7bf575bc2f791507542c63b6d07 115 PRINTS PR01650 Bacterial translocase SecE signature 77 97 8.4E-15 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 Tharo_2737 cef0e7bf575bc2f791507542c63b6d07 115 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 57 107 2.0E-17 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 Tharo_1624 2ded4b5bce350df05155b518b0ddb9af 388 Gene3D G3DSA:1.20.1250.20 198 386 4.4E-14 T 14-10-2018 Tharo_1624 2ded4b5bce350df05155b518b0ddb9af 388 Pfam PF07690 Major Facilitator Superfamily 20 346 3.2E-16 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_1624 2ded4b5bce350df05155b518b0ddb9af 388 Gene3D G3DSA:1.20.1250.20 1 184 1.2E-11 T 14-10-2018 Tharo_1624 2ded4b5bce350df05155b518b0ddb9af 388 SUPERFAMILY SSF103473 2 383 4.19E-34 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_1449 13ddabef455cb7c8cb14daa458666b04 328 Gene3D G3DSA:3.40.250.10 186 317 2.5E-22 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Tharo_1449 13ddabef455cb7c8cb14daa458666b04 328 Pfam PF00581 Rhodanese-like domain 188 303 1.4E-6 T 14-10-2018 IPR001763 Rhodanese-like domain Tharo_1449 13ddabef455cb7c8cb14daa458666b04 328 Pfam PF00581 Rhodanese-like domain 46 159 5.7E-17 T 14-10-2018 IPR001763 Rhodanese-like domain Tharo_1449 13ddabef455cb7c8cb14daa458666b04 328 SUPERFAMILY SSF52821 180 311 1.7E-20 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Tharo_1449 13ddabef455cb7c8cb14daa458666b04 328 SUPERFAMILY SSF52821 40 213 9.3E-30 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Tharo_1449 13ddabef455cb7c8cb14daa458666b04 328 SMART SM00450 44 162 7.5E-17 T 14-10-2018 IPR001763 Rhodanese-like domain Tharo_1449 13ddabef455cb7c8cb14daa458666b04 328 SMART SM00450 186 307 1.0E-5 T 14-10-2018 IPR001763 Rhodanese-like domain Tharo_1449 13ddabef455cb7c8cb14daa458666b04 328 Gene3D G3DSA:3.40.250.10 30 182 4.6E-34 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Tharo_1271 054489c8018b51ef3e1ac68993e04487 478 Pfam PF13375 RnfC Barrel sandwich hybrid domain 5 106 8.9E-36 T 14-10-2018 IPR026902 RnfC Barrel sandwich hybrid domain Tharo_1271 054489c8018b51ef3e1ac68993e04487 478 Gene3D G3DSA:3.10.20.600 286 351 1.8E-5 T 14-10-2018 Tharo_1271 054489c8018b51ef3e1ac68993e04487 478 Gene3D G3DSA:1.10.1060.10 356 437 4.5E-10 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Tharo_1271 054489c8018b51ef3e1ac68993e04487 478 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 407 418 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_1271 054489c8018b51ef3e1ac68993e04487 478 Hamap MF_00461 Ion-translocating oxidoreductase complex subunit C [rsxC]. 1 478 163.789 T 14-10-2018 IPR010208 Ion-translocating oxidoreductase complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 Tharo_1271 054489c8018b51ef3e1ac68993e04487 478 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 4 437 2.0E-171 T 14-10-2018 IPR010208 Ion-translocating oxidoreductase complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 Tharo_1271 054489c8018b51ef3e1ac68993e04487 478 Pfam PF10531 SLBB domain 288 335 1.0E-14 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1271 054489c8018b51ef3e1ac68993e04487 478 SUPERFAMILY SSF142019 87 295 4.84E-55 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1271 054489c8018b51ef3e1ac68993e04487 478 SUPERFAMILY SSF46548 327 436 2.27E-19 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Tharo_1271 054489c8018b51ef3e1ac68993e04487 478 Gene3D G3DSA:3.40.50.11540 135 276 3.1E-11 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1271 054489c8018b51ef3e1ac68993e04487 478 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 130 275 2.0E-45 T 14-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1271 054489c8018b51ef3e1ac68993e04487 478 Pfam PF12838 4Fe-4S dicluster domain 367 420 8.2E-9 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_1506 dbaf37c19ed09d61b04e915a2441b616 352 Pfam PF13177 DNA polymerase III, delta subunit 19 184 4.0E-39 T 14-10-2018 Tharo_1506 dbaf37c19ed09d61b04e915a2441b616 352 SUPERFAMILY SSF52540 5 222 1.59E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1506 dbaf37c19ed09d61b04e915a2441b616 352 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 18 217 8.7E-60 T 14-10-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_1506 dbaf37c19ed09d61b04e915a2441b616 352 Gene3D G3DSA:3.40.50.300 2 185 1.3E-47 T 14-10-2018 Tharo_1741 ff71784296fe75eddee16c9d950ab7cf 296 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 16 270 1.8E-27 T 14-10-2018 IPR017039 Virulence factor BrkB Tharo_1741 ff71784296fe75eddee16c9d950ab7cf 296 Pfam PF03631 Virulence factor BrkB 18 273 3.2E-52 T 14-10-2018 IPR017039 Virulence factor BrkB Tharo_1741 ff71784296fe75eddee16c9d950ab7cf 296 PIRSF PIRSF035875 1 292 1.5E-64 T 14-10-2018 IPR017039 Virulence factor BrkB Tharo_0340 7c8a2f7e91dcc1b88ca9e64e36ab62ff 406 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 140 7.8E-22 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 Tharo_0340 7c8a2f7e91dcc1b88ca9e64e36ab62ff 406 Gene3D G3DSA:1.20.1330.10 40 230 7.7E-49 T 14-10-2018 Tharo_0340 7c8a2f7e91dcc1b88ca9e64e36ab62ff 406 Gene3D G3DSA:1.20.1330.10 249 381 1.3E-13 T 14-10-2018 Tharo_0340 7c8a2f7e91dcc1b88ca9e64e36ab62ff 406 SUPERFAMILY SSF64518 1 404 2.62E-73 T 14-10-2018 Tharo_0340 7c8a2f7e91dcc1b88ca9e64e36ab62ff 406 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 404 1.5E-92 T 14-10-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 Tharo_0112 64ba84b98c52cc192aceb59aca15b30e 81 PRINTS PR00124 ATP synthase C subunit signature 11 30 1.7E-6 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0112 64ba84b98c52cc192aceb59aca15b30e 81 PRINTS PR00124 ATP synthase C subunit signature 49 74 1.7E-6 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0112 64ba84b98c52cc192aceb59aca15b30e 81 PRINTS PR00124 ATP synthase C subunit signature 32 47 1.7E-6 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0112 64ba84b98c52cc192aceb59aca15b30e 81 SUPERFAMILY SSF81333 3 78 4.18E-20 T 14-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily Tharo_0112 64ba84b98c52cc192aceb59aca15b30e 81 Gene3D G3DSA:1.20.20.10 1 77 3.1E-28 T 14-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0112 64ba84b98c52cc192aceb59aca15b30e 81 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 20 76 4.6E-22 T 14-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 Tharo_0112 64ba84b98c52cc192aceb59aca15b30e 81 ProSitePatterns PS00605 ATP synthase c subunit signature. 39 60 - T 14-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0112 64ba84b98c52cc192aceb59aca15b30e 81 Hamap MF_01396 ATP synthase subunit c [atpH]. 9 74 14.561 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0112 64ba84b98c52cc192aceb59aca15b30e 81 Pfam PF00137 ATP synthase subunit C 10 72 2.8E-12 T 14-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 Tharo_0857 d43e18ebd46fb08ceda3a6bd58a6da89 186 Pfam PF11136 Protein of unknown function (DUF2889) 11 134 2.3E-41 T 14-10-2018 IPR021312 Protein of unknown function DUF2889 Tharo_2196 8d26ce5edbdb329bbb70c9dc858f5a54 461 Pfam PF13742 OB-fold nucleic acid binding domain 24 116 2.7E-29 T 14-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 Tharo_2196 8d26ce5edbdb329bbb70c9dc858f5a54 461 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 25 369 6.6E-122 T 14-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 Tharo_2196 8d26ce5edbdb329bbb70c9dc858f5a54 461 Pfam PF02601 Exonuclease VII, large subunit 140 453 1.1E-87 T 14-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 Tharo_2196 8d26ce5edbdb329bbb70c9dc858f5a54 461 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 21 456 28.047 T 14-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 Tharo_0085 a6b90061c8147f013102bd1c6e4b8261 150 Pfam PF12802 MarR family 32 90 1.6E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_0085 a6b90061c8147f013102bd1c6e4b8261 150 SUPERFAMILY SSF46785 4 139 2.01E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0085 a6b90061c8147f013102bd1c6e4b8261 150 SMART SM00347 26 126 3.2E-16 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_0085 a6b90061c8147f013102bd1c6e4b8261 150 ProSitePatterns PS01117 MarR-type HTH domain signature. 65 99 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site Tharo_0085 a6b90061c8147f013102bd1c6e4b8261 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 9.2E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_0085 a6b90061c8147f013102bd1c6e4b8261 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 9.2E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_0085 a6b90061c8147f013102bd1c6e4b8261 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 9.2E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_0085 a6b90061c8147f013102bd1c6e4b8261 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 9.2E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_0085 a6b90061c8147f013102bd1c6e4b8261 150 Gene3D G3DSA:1.10.10.10 1 146 1.1E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0461 b072ba2852e5443cc2da44974ed02c4e 277 PIRSF PIRSF015626 7 277 4.1E-74 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 Tharo_0461 b072ba2852e5443cc2da44974ed02c4e 277 Gene3D G3DSA:3.40.140.10 130 277 6.0E-38 T 14-10-2018 Tharo_0461 b072ba2852e5443cc2da44974ed02c4e 277 Gene3D G3DSA:3.10.20.10 39 121 3.3E-9 T 14-10-2018 Tharo_0461 b072ba2852e5443cc2da44974ed02c4e 277 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 16 275 27.089 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 Tharo_0461 b072ba2852e5443cc2da44974ed02c4e 277 SUPERFAMILY SSF53927 24 274 6.32E-68 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Tharo_0461 b072ba2852e5443cc2da44974ed02c4e 277 Pfam PF02634 FdhD/NarQ family 38 274 1.5E-74 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 Tharo_2363 83b6a21e5d6a42a0303ad506360017c7 463 SUPERFAMILY SSF53738 156 257 2.0E-32 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_2363 83b6a21e5d6a42a0303ad506360017c7 463 Gene3D G3DSA:3.30.310.50 370 463 7.7E-25 T 14-10-2018 Tharo_2363 83b6a21e5d6a42a0303ad506360017c7 463 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 260 358 3.2E-18 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_2363 83b6a21e5d6a42a0303ad506360017c7 463 Gene3D G3DSA:3.40.120.10 174 251 1.6E-34 T 14-10-2018 Tharo_2363 83b6a21e5d6a42a0303ad506360017c7 463 Gene3D G3DSA:3.40.120.10 5 154 2.8E-52 T 14-10-2018 Tharo_2363 83b6a21e5d6a42a0303ad506360017c7 463 SUPERFAMILY SSF55957 368 463 4.97E-20 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_2363 83b6a21e5d6a42a0303ad506360017c7 463 SUPERFAMILY SSF53738 10 142 8.24E-38 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_2363 83b6a21e5d6a42a0303ad506360017c7 463 SUPERFAMILY SSF53738 260 357 9.81E-30 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_2363 83b6a21e5d6a42a0303ad506360017c7 463 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 235 250 4.1E-23 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_2363 83b6a21e5d6a42a0303ad506360017c7 463 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 4.1E-23 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_2363 83b6a21e5d6a42a0303ad506360017c7 463 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 206 219 4.1E-23 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_2363 83b6a21e5d6a42a0303ad506360017c7 463 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 101 115 4.1E-23 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_2363 83b6a21e5d6a42a0303ad506360017c7 463 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 13 138 4.4E-33 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_2363 83b6a21e5d6a42a0303ad506360017c7 463 Gene3D G3DSA:3.40.120.10 252 369 2.7E-38 T 14-10-2018 Tharo_2363 83b6a21e5d6a42a0303ad506360017c7 463 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 255 7.5E-28 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_2363 83b6a21e5d6a42a0303ad506360017c7 463 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 390 452 1.2E-10 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Tharo_1486 e3148f56b1f3712d69e359d30df42a03 393 SUPERFAMILY SSF51230 1 92 7.59E-28 T 14-10-2018 IPR011053 Single hybrid motif Tharo_1486 e3148f56b1f3712d69e359d30df42a03 393 Gene3D G3DSA:3.30.559.10 161 393 2.7E-93 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 Tharo_1486 e3148f56b1f3712d69e359d30df42a03 393 SUPERFAMILY SSF52777 163 392 1.78E-86 T 14-10-2018 Tharo_1486 e3148f56b1f3712d69e359d30df42a03 393 Pfam PF02817 e3 binding domain 109 140 5.9E-12 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 Tharo_1486 e3148f56b1f3712d69e359d30df42a03 393 SUPERFAMILY SSF47005 107 145 2.22E-9 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Tharo_1486 e3148f56b1f3712d69e359d30df42a03 393 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 3 393 4.6E-168 T 14-10-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 Tharo_1486 e3148f56b1f3712d69e359d30df42a03 393 Gene3D G3DSA:4.10.320.10 104 158 1.8E-11 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Tharo_1486 e3148f56b1f3712d69e359d30df42a03 393 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 162 390 2.3E-79 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 Tharo_1486 e3148f56b1f3712d69e359d30df42a03 393 Pfam PF00364 Biotin-requiring enzyme 4 76 2.1E-20 T 14-10-2018 IPR000089 Biotin/lipoyl attachment Tharo_1486 e3148f56b1f3712d69e359d30df42a03 393 Gene3D G3DSA:2.40.50.100 2 101 1.1E-25 T 14-10-2018 Tharo_2027 29a3f3cbd18b71a9fad518846e8a2a43 378 Gene3D G3DSA:2.40.370.10 239 377 1.8E-45 T 14-10-2018 IPR023374 AttH-like domain superfamily Tharo_2027 29a3f3cbd18b71a9fad518846e8a2a43 378 Pfam PF07143 CrtC N-terminal lipocalin domain 63 234 6.1E-51 T 14-10-2018 IPR010791 AttH domain Tharo_2027 29a3f3cbd18b71a9fad518846e8a2a43 378 Pfam PF17186 Lipocalin-like domain 238 372 1.3E-40 T 14-10-2018 Tharo_2027 29a3f3cbd18b71a9fad518846e8a2a43 378 SUPERFAMILY SSF159245 40 372 4.97E-104 T 14-10-2018 Tharo_2027 29a3f3cbd18b71a9fad518846e8a2a43 378 Gene3D G3DSA:2.40.370.10 51 237 4.9E-69 T 14-10-2018 IPR023374 AttH-like domain superfamily Tharo_0123 e9f73fbd5673ef3bc688522890e6ae3f 236 SMART SM00862 150 225 1.5E-28 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_0123 e9f73fbd5673ef3bc688522890e6ae3f 236 SUPERFAMILY SSF46894 125 226 2.3E-31 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_0123 e9f73fbd5673ef3bc688522890e6ae3f 236 SMART SM00448 3 116 1.9E-44 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_0123 e9f73fbd5673ef3bc688522890e6ae3f 236 Pfam PF00072 Response regulator receiver domain 5 117 2.3E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_0123 e9f73fbd5673ef3bc688522890e6ae3f 236 Gene3D G3DSA:3.40.50.2300 1 128 3.5E-41 T 14-10-2018 Tharo_0123 e9f73fbd5673ef3bc688522890e6ae3f 236 Gene3D G3DSA:1.10.10.10 129 228 3.6E-39 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0123 e9f73fbd5673ef3bc688522890e6ae3f 236 SUPERFAMILY SSF52172 2 127 9.53E-45 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_0123 e9f73fbd5673ef3bc688522890e6ae3f 236 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 2 226 6.7E-111 T 14-10-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 Tharo_0123 e9f73fbd5673ef3bc688522890e6ae3f 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 225 1.6E-27 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_0953 5f08979b1aa67b064bcf7c9ad4606119 126 SUPERFAMILY SSF50630 19 90 1.57E-5 T 14-10-2018 IPR021109 Aspartic peptidase domain superfamily Tharo_0953 5f08979b1aa67b064bcf7c9ad4606119 126 Pfam PF13650 Aspartyl protease 20 66 1.0E-6 T 14-10-2018 Tharo_0953 5f08979b1aa67b064bcf7c9ad4606119 126 Gene3D G3DSA:2.40.70.10 15 122 1.6E-10 T 14-10-2018 IPR021109 Aspartic peptidase domain superfamily Tharo_0953 5f08979b1aa67b064bcf7c9ad4606119 126 TIGRFAM TIGR03698 clan_AA_DTGF: clan AA aspartic protease, AF_0612 family 6 110 1.9E-17 T 14-10-2018 IPR022274 Peptidase aspartic, AF0612 Tharo_0260 0ccb7659a80d5046dfcc048a1ad6ade2 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 8.0E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_0260 0ccb7659a80d5046dfcc048a1ad6ade2 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 8.0E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_0260 0ccb7659a80d5046dfcc048a1ad6ade2 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 8.0E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_0260 0ccb7659a80d5046dfcc048a1ad6ade2 216 SUPERFAMILY SSF52172 9 135 3.7E-34 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_0260 0ccb7659a80d5046dfcc048a1ad6ade2 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 210 9.4E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_0260 0ccb7659a80d5046dfcc048a1ad6ade2 216 SUPERFAMILY SSF46894 146 213 1.94E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_0260 0ccb7659a80d5046dfcc048a1ad6ade2 216 SMART SM00421 153 210 1.7E-22 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_0260 0ccb7659a80d5046dfcc048a1ad6ade2 216 Pfam PF00072 Response regulator receiver domain 9 120 2.1E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_0260 0ccb7659a80d5046dfcc048a1ad6ade2 216 SMART SM00448 7 120 7.4E-34 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_0260 0ccb7659a80d5046dfcc048a1ad6ade2 216 Gene3D G3DSA:3.40.50.12740 8 214 2.7E-64 T 14-10-2018 Tharo_0260 0ccb7659a80d5046dfcc048a1ad6ade2 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_1199 788206e2d27a3f29ba13e24b8e56452d 196 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 24 182 1.7E-51 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Tharo_1199 788206e2d27a3f29ba13e24b8e56452d 196 PIRSF PIRSF001467 10 187 1.1E-32 T 14-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 Tharo_1199 788206e2d27a3f29ba13e24b8e56452d 196 Gene3D G3DSA:2.40.100.10 20 184 9.8E-67 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily Tharo_1199 788206e2d27a3f29ba13e24b8e56452d 196 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 64 76 9.1E-15 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Tharo_1199 788206e2d27a3f29ba13e24b8e56452d 196 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 38 53 9.1E-15 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Tharo_1199 788206e2d27a3f29ba13e24b8e56452d 196 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 139 154 9.1E-15 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Tharo_1199 788206e2d27a3f29ba13e24b8e56452d 196 SUPERFAMILY SSF50891 21 184 1.31E-61 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily Tharo_1199 788206e2d27a3f29ba13e24b8e56452d 196 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 59 76 - T 14-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 Tharo_1573 b484940be054e60d8acd138e40ce6ae3 767 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 40 163 3.1E-37 T 14-10-2018 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 Tharo_1573 b484940be054e60d8acd138e40ce6ae3 767 Gene3D G3DSA:3.90.1150.10 477 649 4.9E-69 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_1573 b484940be054e60d8acd138e40ce6ae3 767 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 630 753 5.9E-47 T 14-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 Tharo_1573 b484940be054e60d8acd138e40ce6ae3 767 Gene3D G3DSA:3.90.100.10 650 767 3.4E-42 T 14-10-2018 Tharo_1573 b484940be054e60d8acd138e40ce6ae3 767 Gene3D G3DSA:3.40.50.2300 25 167 5.7E-21 T 14-10-2018 Tharo_1573 b484940be054e60d8acd138e40ce6ae3 767 SUPERFAMILY SSF53383 169 623 1.38E-119 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_1573 b484940be054e60d8acd138e40ce6ae3 767 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 169 603 5.1E-150 T 14-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 Tharo_1573 b484940be054e60d8acd138e40ce6ae3 767 Gene3D G3DSA:3.40.640.10 169 474 1.5E-96 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_1573 b484940be054e60d8acd138e40ce6ae3 767 SUPERFAMILY SSF55904 625 762 1.7E-45 T 14-10-2018 IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily GO:0003824 Tharo_1573 b484940be054e60d8acd138e40ce6ae3 767 PIRSF PIRSF009393 21 767 5.1E-277 T 14-10-2018 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 Tharo_1573 b484940be054e60d8acd138e40ce6ae3 767 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 410 424 - T 14-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 Tharo_0793 e8f6e5e41e83803d545fde19feef4e11 217 PIRSF PIRSF006324 1 210 2.7E-54 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 Tharo_0793 e8f6e5e41e83803d545fde19feef4e11 217 Pfam PF01810 LysE type translocator 17 208 5.4E-32 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 Tharo_0324 562ba7f599cc60f6808c8bc0b0289778 576 Gene3D G3DSA:3.20.20.60 240 576 2.4E-112 T 14-10-2018 Tharo_0324 562ba7f599cc60f6808c8bc0b0289778 576 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 453 468 4.8E-26 T 14-10-2018 Tharo_0324 562ba7f599cc60f6808c8bc0b0289778 576 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 470 485 4.8E-26 T 14-10-2018 Tharo_0324 562ba7f599cc60f6808c8bc0b0289778 576 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 299 318 4.8E-26 T 14-10-2018 Tharo_0324 562ba7f599cc60f6808c8bc0b0289778 576 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 506 518 4.8E-26 T 14-10-2018 Tharo_0324 562ba7f599cc60f6808c8bc0b0289778 576 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 6 568 6.8E-154 T 14-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 Tharo_0324 562ba7f599cc60f6808c8bc0b0289778 576 PIRSF PIRSF000732 1 576 2.0E-202 T 14-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 Tharo_0324 562ba7f599cc60f6808c8bc0b0289778 576 SUPERFAMILY SSF47831 28 147 2.48E-26 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 Tharo_0324 562ba7f599cc60f6808c8bc0b0289778 576 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 258 546 7.2E-104 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 Tharo_0324 562ba7f599cc60f6808c8bc0b0289778 576 Gene3D G3DSA:3.50.30.10 7 239 3.3E-69 T 14-10-2018 Tharo_0324 562ba7f599cc60f6808c8bc0b0289778 576 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 130 9.6E-27 T 14-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 Tharo_0324 562ba7f599cc60f6808c8bc0b0289778 576 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 190 201 - T 14-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 Tharo_0324 562ba7f599cc60f6808c8bc0b0289778 576 SUPERFAMILY SSF51621 255 552 1.62E-98 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Tharo_0324 562ba7f599cc60f6808c8bc0b0289778 576 Gene3D G3DSA:1.10.274.10 24 150 3.3E-69 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 Tharo_0324 562ba7f599cc60f6808c8bc0b0289778 576 Pfam PF00391 PEP-utilising enzyme, mobile domain 161 231 1.0E-23 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 Tharo_0324 562ba7f599cc60f6808c8bc0b0289778 576 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 453 471 - T 14-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 Tharo_0324 562ba7f599cc60f6808c8bc0b0289778 576 SUPERFAMILY SSF52009 129 249 3.79E-31 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 Tharo_0549 d99e898827d33e718a8c0356dc56e13e 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 44.621 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 Tharo_0549 d99e898827d33e718a8c0356dc56e13e 363 Pfam PF01926 50S ribosome-binding GTPase 5 123 1.2E-23 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_0549 d99e898827d33e718a8c0356dc56e13e 363 PIRSF PIRSF006641 1 363 9.2E-153 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 Tharo_0549 d99e898827d33e718a8c0356dc56e13e 363 SUPERFAMILY SSF81271 279 359 1.37E-35 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 Tharo_0549 d99e898827d33e718a8c0356dc56e13e 363 SUPERFAMILY SSF52540 3 301 1.5E-85 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0549 d99e898827d33e718a8c0356dc56e13e 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 4.6E-35 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_0549 d99e898827d33e718a8c0356dc56e13e 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 4.6E-35 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_0549 d99e898827d33e718a8c0356dc56e13e 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 4.6E-35 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_0549 d99e898827d33e718a8c0356dc56e13e 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 4.6E-35 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_0549 d99e898827d33e718a8c0356dc56e13e 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 4.9E-39 T 14-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 Tharo_0549 d99e898827d33e718a8c0356dc56e13e 363 Gene3D G3DSA:1.10.150.300 113 200 4.3E-151 T 14-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 Tharo_0549 d99e898827d33e718a8c0356dc56e13e 363 Gene3D G3DSA:3.40.50.300 3 278 4.3E-151 T 14-10-2018 Tharo_0549 d99e898827d33e718a8c0356dc56e13e 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 3.2E-156 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 Tharo_0549 d99e898827d33e718a8c0356dc56e13e 363 Gene3D G3DSA:3.10.20.30 48 361 4.3E-151 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Tharo_0032 c8596ee979a181d2289dfad6f73b268f 311 Pfam PF03547 Membrane transport protein 155 303 3.5E-13 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 Tharo_0032 c8596ee979a181d2289dfad6f73b268f 311 Pfam PF03547 Membrane transport protein 6 133 9.7E-18 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 Tharo_2264 44e903362faa57258d811b8849dccd4f 110 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 19 107 3.4E-27 T 14-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 Tharo_2264 44e903362faa57258d811b8849dccd4f 110 Gene3D G3DSA:3.30.1360.20 19 110 7.7E-30 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 Tharo_2264 44e903362faa57258d811b8849dccd4f 110 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 17 110 21.496 T 14-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 Tharo_2264 44e903362faa57258d811b8849dccd4f 110 SUPERFAMILY SSF55248 17 108 1.15E-30 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 Tharo_2253 93cd62f88a7c3d321123eebad060fe59 617 Gene3D G3DSA:3.40.190.10 40 270 1.0E-10 T 14-10-2018 Tharo_2253 93cd62f88a7c3d321123eebad060fe59 617 SUPERFAMILY SSF53850 51 274 4.76E-14 T 14-10-2018 Tharo_2253 93cd62f88a7c3d321123eebad060fe59 617 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 39 276 3.2E-28 T 14-10-2018 Tharo_2253 93cd62f88a7c3d321123eebad060fe59 617 SUPERFAMILY SSF55874 429 592 2.88E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2253 93cd62f88a7c3d321123eebad060fe59 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 554 572 9.4E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2253 93cd62f88a7c3d321123eebad060fe59 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 579 592 9.4E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2253 93cd62f88a7c3d321123eebad060fe59 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 539 9.4E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2253 93cd62f88a7c3d321123eebad060fe59 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 543 553 9.4E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2253 93cd62f88a7c3d321123eebad060fe59 617 SUPERFAMILY SSF47384 367 439 2.16E-8 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_2253 93cd62f88a7c3d321123eebad060fe59 617 Pfam PF00512 His Kinase A (phospho-acceptor) domain 373 440 8.9E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_2253 93cd62f88a7c3d321123eebad060fe59 617 SMART SM00387 484 595 1.6E-32 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2253 93cd62f88a7c3d321123eebad060fe59 617 Gene3D G3DSA:1.10.287.130 378 435 2.0E-15 T 14-10-2018 Tharo_2253 93cd62f88a7c3d321123eebad060fe59 617 Gene3D G3DSA:3.40.190.10 125 241 1.0E-10 T 14-10-2018 Tharo_2253 93cd62f88a7c3d321123eebad060fe59 617 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 485 593 4.5E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2253 93cd62f88a7c3d321123eebad060fe59 617 SMART SM00388 372 442 1.5E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_2253 93cd62f88a7c3d321123eebad060fe59 617 Gene3D G3DSA:3.30.565.10 436 593 3.1E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1618 76776cb714ded4e965df8e08ee59e85c 310 SUPERFAMILY SSF54814 195 310 1.4E-40 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Tharo_1618 76776cb714ded4e965df8e08ee59e85c 310 Gene3D G3DSA:3.30.300.20 199 310 2.5E-38 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta Tharo_1618 76776cb714ded4e965df8e08ee59e85c 310 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 119 137 1.5E-6 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_1618 76776cb714ded4e965df8e08ee59e85c 310 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 25 45 1.5E-6 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_1618 76776cb714ded4e965df8e08ee59e85c 310 Hamap MF_00367 GTPase Era [era]. 20 309 35.273 T 14-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1618 76776cb714ded4e965df8e08ee59e85c 310 Gene3D G3DSA:3.40.50.300 18 196 6.2E-47 T 14-10-2018 Tharo_1618 76776cb714ded4e965df8e08ee59e85c 310 Pfam PF07650 KH domain 222 297 7.7E-18 T 14-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_1618 76776cb714ded4e965df8e08ee59e85c 310 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 22 179 2.2E-33 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Tharo_1618 76776cb714ded4e965df8e08ee59e85c 310 TIGRFAM TIGR00436 era: GTP-binding protein Era 23 292 3.9E-86 T 14-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1618 76776cb714ded4e965df8e08ee59e85c 310 SUPERFAMILY SSF52540 25 216 3.51E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1618 76776cb714ded4e965df8e08ee59e85c 310 Pfam PF01926 50S ribosome-binding GTPase 25 138 3.9E-25 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_1023 6eb2162ef444cf2c123b7a5fc75eaf5a 271 Pfam PF00881 Nitroreductase family 31 183 2.2E-23 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 Tharo_1023 6eb2162ef444cf2c123b7a5fc75eaf5a 271 PIRSF PIRSF005426 20 271 1.1E-79 T 14-10-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 Tharo_1023 6eb2162ef444cf2c123b7a5fc75eaf5a 271 Gene3D G3DSA:3.40.109.10 21 271 3.5E-66 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Tharo_1023 6eb2162ef444cf2c123b7a5fc75eaf5a 271 SUPERFAMILY SSF55469 22 270 4.45E-64 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Tharo_1513 3963973f6e818bf460d0583f42cee2a4 324 Gene3D G3DSA:3.30.390.50 217 324 5.5E-22 T 14-10-2018 Tharo_1513 3963973f6e818bf460d0583f42cee2a4 324 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 221 318 8.2E-7 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal Tharo_1513 3963973f6e818bf460d0583f42cee2a4 324 SUPERFAMILY SSF55447 218 322 1.83E-22 T 14-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily Tharo_1513 3963973f6e818bf460d0583f42cee2a4 324 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 6 214 2.5E-40 T 14-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 Tharo_1513 3963973f6e818bf460d0583f42cee2a4 324 SMART SM01092 220 320 1.2E-9 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal Tharo_1513 3963973f6e818bf460d0583f42cee2a4 324 Gene3D G3DSA:3.30.465.10 1 216 5.9E-85 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Tharo_1513 3963973f6e818bf460d0583f42cee2a4 324 TIGRFAM TIGR03195 4hydrxCoA_B: 4-hydroxybenzoyl-CoA reductase, beta subunit 3 322 1.3E-169 T 14-10-2018 IPR017608 4-hydroxybenzoyl-CoA reductase, beta subunit KEGG: 00362+1.3.7.9|KEGG: 00627+1.3.7.9|MetaCyc: PWY-6080|MetaCyc: PWY-7046 Tharo_1513 3963973f6e818bf460d0583f42cee2a4 324 SUPERFAMILY SSF56176 3 214 1.56E-57 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Tharo_2970 36ece4c64e4b23dbfa75dd945147664e 107 SUPERFAMILY SSF69754 1 101 2.09E-35 T 14-10-2018 IPR036567 Ribosome hibernation promotion factor-like Tharo_2970 36ece4c64e4b23dbfa75dd945147664e 107 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 98 1.7E-31 T 14-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 Tharo_2970 36ece4c64e4b23dbfa75dd945147664e 107 Gene3D G3DSA:3.30.160.100 1 105 1.2E-36 T 14-10-2018 IPR036567 Ribosome hibernation promotion factor-like Tharo_2970 36ece4c64e4b23dbfa75dd945147664e 107 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 92 4.3E-27 T 14-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 Tharo_1059 deb19dd9aa38e14c2404ca5e15e1daf6 208 Pfam PF04367 Protein of unknown function (DUF502) 57 161 1.5E-36 T 14-10-2018 IPR007462 Protein of unknown function DUF502 Tharo_2549 5e4cf337bc48b9d2a9d90bc30a831ce3 160 SUPERFAMILY SSF47741 88 153 8.9E-28 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily Tharo_2549 5e4cf337bc48b9d2a9d90bc30a831ce3 160 Pfam PF01799 [2Fe-2S] binding domain 77 149 2.9E-28 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Tharo_2549 5e4cf337bc48b9d2a9d90bc30a831ce3 160 SUPERFAMILY SSF54292 5 82 6.95E-25 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Tharo_2549 5e4cf337bc48b9d2a9d90bc30a831ce3 160 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 59 1.1E-8 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Tharo_2549 5e4cf337bc48b9d2a9d90bc30a831ce3 160 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 43 51 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Tharo_2549 5e4cf337bc48b9d2a9d90bc30a831ce3 160 Gene3D G3DSA:1.10.150.120 80 158 3.0E-29 T 14-10-2018 Tharo_2549 5e4cf337bc48b9d2a9d90bc30a831ce3 160 Gene3D G3DSA:3.10.20.30 1 79 1.7E-28 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Tharo_0514 1e269769cbb21e0d726bbc7aadb48d95 292 Pfam PF05673 Protein of unknown function (DUF815) 33 284 3.0E-108 T 14-10-2018 IPR008533 Domain of unknown function DUF815 Tharo_0514 1e269769cbb21e0d726bbc7aadb48d95 292 Gene3D G3DSA:3.40.50.300 54 195 3.3E-11 T 14-10-2018 Tharo_0514 1e269769cbb21e0d726bbc7aadb48d95 292 SMART SM00382 84 211 8.4E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0514 1e269769cbb21e0d726bbc7aadb48d95 292 SUPERFAMILY SSF52540 44 190 9.58E-29 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0903 880ca1d8ec437f39151a9ece33c1e75c 300 PIRSF PIRSF000401 1 299 3.7E-87 T 14-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 Tharo_0903 880ca1d8ec437f39151a9ece33c1e75c 300 SUPERFAMILY SSF53335 56 275 4.48E-42 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_0903 880ca1d8ec437f39151a9ece33c1e75c 300 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 297 8.8E-88 T 14-10-2018 Tharo_0903 880ca1d8ec437f39151a9ece33c1e75c 300 Gene3D G3DSA:3.40.50.150 109 298 2.9E-60 T 14-10-2018 Tharo_0903 880ca1d8ec437f39151a9ece33c1e75c 300 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 2 297 31.044 T 14-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 Tharo_0903 880ca1d8ec437f39151a9ece33c1e75c 300 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 2 286 1.2E-70 T 14-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 Tharo_0275 15f2e2295d987b50b463eb247f340c19 98 SMART SM00530 28 83 1.7E-10 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_0275 15f2e2295d987b50b463eb247f340c19 98 SUPERFAMILY SSF47413 16 89 2.76E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_0275 15f2e2295d987b50b463eb247f340c19 98 Gene3D G3DSA:1.10.260.40 8 91 7.5E-16 T 14-10-2018 Tharo_0275 15f2e2295d987b50b463eb247f340c19 98 Pfam PF01381 Helix-turn-helix 29 81 9.2E-11 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_0607 1a512a71ea249bdf309ce95675879de5 701 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 8 563 1.5E-199 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Tharo_0607 1a512a71ea249bdf309ce95675879de5 701 SUPERFAMILY SSF109604 350 503 2.83E-15 T 14-10-2018 Tharo_0607 1a512a71ea249bdf309ce95675879de5 701 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 5 699 24.198 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Tharo_0607 1a512a71ea249bdf309ce95675879de5 701 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 257 272 3.5E-33 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Tharo_0607 1a512a71ea249bdf309ce95675879de5 701 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 329 345 3.5E-33 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Tharo_0607 1a512a71ea249bdf309ce95675879de5 701 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 9 22 3.5E-33 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Tharo_0607 1a512a71ea249bdf309ce95675879de5 701 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 54 66 3.5E-33 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Tharo_0607 1a512a71ea249bdf309ce95675879de5 701 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 405 424 3.5E-33 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Tharo_0607 1a512a71ea249bdf309ce95675879de5 701 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 6 699 1.0E-206 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Tharo_0607 1a512a71ea249bdf309ce95675879de5 701 Pfam PF05746 DALR anticodon binding domain 594 692 2.4E-9 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 Tharo_0707 1cd29b83aeb6d4c56642e83fd152e385 727 SUPERFAMILY SSF52540 146 659 2.15E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0707 1cd29b83aeb6d4c56642e83fd152e385 727 Pfam PF12696 TraM recognition site of TraD and TraG 509 636 1.7E-10 T 14-10-2018 IPR032689 TraD/TraG, TraM recognition site Tharo_0707 1cd29b83aeb6d4c56642e83fd152e385 727 TIGRFAM TIGR03754 conj_TOL_TraD: conjugative coupling factor TraD, PFGI-1 class 7 657 0.0 T 14-10-2018 IPR022503 Conjugative coupling factor TraG/TraD, PFGI-1 Tharo_0707 1cd29b83aeb6d4c56642e83fd152e385 727 TIGRFAM TIGR03743 SXT_TraD: conjugative coupling factor TraD, SXT/TOL subfamily 7 657 3.6E-265 T 14-10-2018 IPR022458 Conjugative coupling factor TraG/TraD Tharo_0707 1cd29b83aeb6d4c56642e83fd152e385 727 Gene3D G3DSA:3.40.50.300 160 332 6.0E-8 T 14-10-2018 Tharo_0707 1cd29b83aeb6d4c56642e83fd152e385 727 Gene3D G3DSA:3.40.50.300 419 660 5.5E-27 T 14-10-2018 Tharo_1570 3b5ec24f754e62bf358c2ca1d8c916f2 192 SUPERFAMILY SSF103088 77 190 9.55E-32 T 14-10-2018 IPR036737 OmpA-like domain superfamily Tharo_1570 3b5ec24f754e62bf358c2ca1d8c916f2 192 Pfam PF00691 OmpA family 88 182 9.0E-19 T 14-10-2018 IPR006665 OmpA-like domain Tharo_1570 3b5ec24f754e62bf358c2ca1d8c916f2 192 Gene3D G3DSA:3.30.1330.60 55 191 3.5E-34 T 14-10-2018 IPR036737 OmpA-like domain superfamily Tharo_1570 3b5ec24f754e62bf358c2ca1d8c916f2 192 PRINTS PR01021 OMPA domain signature 118 133 6.9E-10 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Tharo_1570 3b5ec24f754e62bf358c2ca1d8c916f2 192 PRINTS PR01021 OMPA domain signature 133 149 6.9E-10 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Tharo_1570 3b5ec24f754e62bf358c2ca1d8c916f2 192 PRINTS PR01021 OMPA domain signature 88 110 6.9E-10 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Tharo_2759 a33ee5fc31801beb4b8eff747d946d8d 437 SMART SM00382 164 357 2.8E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2759 a33ee5fc31801beb4b8eff747d946d8d 437 Gene3D G3DSA:3.40.50.300 131 215 3.5E-5 T 14-10-2018 Tharo_2759 a33ee5fc31801beb4b8eff747d946d8d 437 Gene3D G3DSA:1.10.8.60 356 408 2.2E-5 T 14-10-2018 Tharo_2759 a33ee5fc31801beb4b8eff747d946d8d 437 SUPERFAMILY SSF52540 138 388 9.77E-21 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2759 a33ee5fc31801beb4b8eff747d946d8d 437 Gene3D G3DSA:3.40.50.300 294 355 2.2E-5 T 14-10-2018 Tharo_1305 c36bcaff60d7677dd1393fe061a8eff4 386 Gene3D G3DSA:1.20.1270.370 19 224 2.8E-65 T 14-10-2018 Tharo_1305 c36bcaff60d7677dd1393fe061a8eff4 386 Gene3D G3DSA:3.40.50.11890 32 159 2.8E-65 T 14-10-2018 Tharo_1305 c36bcaff60d7677dd1393fe061a8eff4 386 TIGRFAM TIGR02263 benz_CoA_red_C: benzoyl-CoA reductase, subunit C 3 382 2.0E-253 T 14-10-2018 IPR011958 Benzoyl-CoA reductase, subunit C KEGG: 00362+1.3.7.8 Tharo_1305 c36bcaff60d7677dd1393fe061a8eff4 386 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 40 378 2.4E-49 T 14-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit Tharo_1305 c36bcaff60d7677dd1393fe061a8eff4 386 Gene3D G3DSA:3.40.50.11900 236 386 2.6E-28 T 14-10-2018 Tharo_3313 92295d393b2292a4c83c16380b9b1e06 192 Gene3D G3DSA:3.40.30.10 25 175 9.9E-7 T 14-10-2018 Tharo_3313 92295d393b2292a4c83c16380b9b1e06 192 SUPERFAMILY SSF52833 17 165 1.28E-8 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_2837 1912d213053534d50ae0561a0ce7d57d 243 Gene3D G3DSA:3.30.1150.10 147 241 4.0E-21 T 14-10-2018 Tharo_2837 1912d213053534d50ae0561a0ce7d57d 243 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 162 240 3.8E-21 T 14-10-2018 IPR037682 TonB, C-terminal GO:0055085 Tharo_2837 1912d213053534d50ae0561a0ce7d57d 243 SUPERFAMILY SSF74653 157 238 2.09E-22 T 14-10-2018 Tharo_2837 1912d213053534d50ae0561a0ce7d57d 243 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 164 240 3.7E-19 T 14-10-2018 IPR006260 TonB/TolA, C-terminal Tharo_2837 1912d213053534d50ae0561a0ce7d57d 243 PRINTS PR01374 Gram-negative bacterial tonB protein signature 158 179 1.8E-6 T 14-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 Tharo_2837 1912d213053534d50ae0561a0ce7d57d 243 PRINTS PR01374 Gram-negative bacterial tonB protein signature 179 197 1.8E-6 T 14-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 Tharo_2837 1912d213053534d50ae0561a0ce7d57d 243 PRINTS PR01374 Gram-negative bacterial tonB protein signature 95 105 1.8E-6 T 14-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 Tharo_2732 95b5992d5e22c976a8d14c29be07008b 124 SUPERFAMILY SSF48300 4 60 1.31E-16 T 14-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2732 95b5992d5e22c976a8d14c29be07008b 124 Gene3D G3DSA:3.30.1390.10 54 124 2.0E-31 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like Tharo_2732 95b5992d5e22c976a8d14c29be07008b 124 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 59 124 6.0E-25 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2732 95b5992d5e22c976a8d14c29be07008b 124 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 124 25.597 T 14-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2732 95b5992d5e22c976a8d14c29be07008b 124 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 52 4.7E-18 T 14-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2732 95b5992d5e22c976a8d14c29be07008b 124 SUPERFAMILY SSF54736 53 124 2.27E-25 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like Tharo_2732 95b5992d5e22c976a8d14c29be07008b 124 Gene3D G3DSA:1.20.5.710 2 53 2.6E-21 T 14-10-2018 Tharo_2732 95b5992d5e22c976a8d14c29be07008b 124 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 124 1.1E-50 T 14-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2732 95b5992d5e22c976a8d14c29be07008b 124 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 58 124 1.3E-30 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_3242 5c396d7f4e953036ee41c859b83c37d3 183 Gene3D G3DSA:3.40.50.1240 1 181 1.5E-33 T 14-10-2018 IPR029033 Histidine phosphatase superfamily Tharo_3242 5c396d7f4e953036ee41c859b83c37d3 183 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 182 1.2E-32 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Tharo_3242 5c396d7f4e953036ee41c859b83c37d3 183 SMART SM00855 2 144 9.0E-13 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Tharo_3242 5c396d7f4e953036ee41c859b83c37d3 183 SUPERFAMILY SSF53254 1 172 2.06E-37 T 14-10-2018 IPR029033 Histidine phosphatase superfamily Tharo_3242 5c396d7f4e953036ee41c859b83c37d3 183 PIRSF PIRSF000709 44 182 9.2E-4 T 14-10-2018 Tharo_3007 94b7e9e042a1db5204bbca48a65a484e 336 SUPERFAMILY SSF56529 76 332 4.19E-58 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Tharo_3007 94b7e9e042a1db5204bbca48a65a484e 336 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 81 332 5.2E-42 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 Tharo_3007 94b7e9e042a1db5204bbca48a65a484e 336 Gene3D G3DSA:3.90.850.10 1 336 4.7E-139 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Tharo_0828 4070d4f821bdd0d8870fde5f6bacd070 168 PRINTS PR01100 Shikimate kinase family signature 20 33 1.3E-12 T 14-10-2018 Tharo_0828 4070d4f821bdd0d8870fde5f6bacd070 168 PRINTS PR01100 Shikimate kinase family signature 48 56 1.3E-12 T 14-10-2018 Tharo_0828 4070d4f821bdd0d8870fde5f6bacd070 168 PRINTS PR01100 Shikimate kinase family signature 66 75 1.3E-12 T 14-10-2018 Tharo_0828 4070d4f821bdd0d8870fde5f6bacd070 168 PRINTS PR01100 Shikimate kinase family signature 87 104 1.3E-12 T 14-10-2018 Tharo_0828 4070d4f821bdd0d8870fde5f6bacd070 168 Pfam PF01202 Shikimate kinase 2 152 5.7E-52 T 14-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 Tharo_0828 4070d4f821bdd0d8870fde5f6bacd070 168 SUPERFAMILY SSF52540 2 158 1.54E-29 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0828 4070d4f821bdd0d8870fde5f6bacd070 168 Hamap MF_00109 Shikimate kinase [aroK]. 1 159 24.482 T 14-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 Tharo_0828 4070d4f821bdd0d8870fde5f6bacd070 168 ProSitePatterns PS01128 Shikimate kinase signature. 49 74 - T 14-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 Tharo_0828 4070d4f821bdd0d8870fde5f6bacd070 168 Gene3D G3DSA:3.40.50.300 1 165 5.7E-53 T 14-10-2018 Tharo_1928 1b01c1f16f7d5884c6b1ab9752647410 187 Pfam PF00293 NUDIX domain 47 161 3.4E-16 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Tharo_1928 1b01c1f16f7d5884c6b1ab9752647410 187 SUPERFAMILY SSF55811 15 180 1.31E-47 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Tharo_1928 1b01c1f16f7d5884c6b1ab9752647410 187 ProSitePatterns PS00893 Nudix box signature. 83 104 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Tharo_1928 1b01c1f16f7d5884c6b1ab9752647410 187 Gene3D G3DSA:3.90.79.10 14 181 3.5E-53 T 14-10-2018 Tharo_1254 9d57435e25c4be09d7a7e17c05ff4915 202 Gene3D G3DSA:2.160.10.10 3 171 9.5E-50 T 14-10-2018 Tharo_1254 9d57435e25c4be09d7a7e17c05ff4915 202 SUPERFAMILY SSF51161 2 165 2.5E-43 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily Tharo_1254 9d57435e25c4be09d7a7e17c05ff4915 202 TIGRFAM TIGR02287 PaaY: phenylacetic acid degradation protein PaaY 3 193 1.3E-100 T 14-10-2018 IPR011974 Phenylacetic acid degradation protein PaaY Tharo_1254 9d57435e25c4be09d7a7e17c05ff4915 202 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 89 122 1.8E-7 T 14-10-2018 IPR001451 Hexapeptide repeat Tharo_1254 9d57435e25c4be09d7a7e17c05ff4915 202 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 44 9.1E-4 T 14-10-2018 IPR001451 Hexapeptide repeat Tharo_2004 29136730b19cd1d8aa1553f3ae38c9c6 404 SUPERFAMILY SSF51338 28 74 1.67E-6 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Tharo_2004 29136730b19cd1d8aa1553f3ae38c9c6 404 Gene3D G3DSA:3.20.20.140 65 361 8.1E-61 T 14-10-2018 Tharo_2004 29136730b19cd1d8aa1553f3ae38c9c6 404 SUPERFAMILY SSF51556 63 357 4.54E-55 T 14-10-2018 IPR032466 Metal-dependent hydrolase Tharo_2004 29136730b19cd1d8aa1553f3ae38c9c6 404 Pfam PF01979 Amidohydrolase family 59 376 2.0E-21 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Tharo_2004 29136730b19cd1d8aa1553f3ae38c9c6 404 Gene3D G3DSA:2.30.40.10 28 388 8.1E-61 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Tharo_0186 29136730b19cd1d8aa1553f3ae38c9c6 404 SUPERFAMILY SSF51338 28 74 1.67E-6 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Tharo_0186 29136730b19cd1d8aa1553f3ae38c9c6 404 Gene3D G3DSA:3.20.20.140 65 361 8.1E-61 T 14-10-2018 Tharo_0186 29136730b19cd1d8aa1553f3ae38c9c6 404 SUPERFAMILY SSF51556 63 357 4.54E-55 T 14-10-2018 IPR032466 Metal-dependent hydrolase Tharo_0186 29136730b19cd1d8aa1553f3ae38c9c6 404 Pfam PF01979 Amidohydrolase family 59 376 2.0E-21 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Tharo_0186 29136730b19cd1d8aa1553f3ae38c9c6 404 Gene3D G3DSA:2.30.40.10 28 388 8.1E-61 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Tharo_1966 b51ea44ea7b88250cf92481e08b327c5 256 Gene3D G3DSA:3.20.20.140 1 251 2.2E-69 T 14-10-2018 Tharo_1966 b51ea44ea7b88250cf92481e08b327c5 256 PIRSF PIRSF005902 1 253 2.2E-60 T 14-10-2018 IPR001130 TatD family GO:0016788 Tharo_1966 b51ea44ea7b88250cf92481e08b327c5 256 Pfam PF01026 TatD related DNase 3 249 7.3E-58 T 14-10-2018 IPR001130 TatD family GO:0016788 Tharo_1966 b51ea44ea7b88250cf92481e08b327c5 256 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 14-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 Tharo_1966 b51ea44ea7b88250cf92481e08b327c5 256 SUPERFAMILY SSF51556 2 249 1.82E-73 T 14-10-2018 IPR032466 Metal-dependent hydrolase Tharo_1966 b51ea44ea7b88250cf92481e08b327c5 256 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 187 203 - T 14-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 Tharo_1966 b51ea44ea7b88250cf92481e08b327c5 256 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 124 134 - T 14-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 Tharo_0486 38d5ed4db339806c0c6d8e24f669ce56 299 SUPERFAMILY SSF53613 8 291 1.8E-41 T 14-10-2018 IPR029056 Ribokinase-like Tharo_0486 38d5ed4db339806c0c6d8e24f669ce56 299 Pfam PF08543 Phosphomethylpyrimidine kinase 185 281 2.8E-16 T 14-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 Tharo_0486 38d5ed4db339806c0c6d8e24f669ce56 299 Pfam PF08543 Phosphomethylpyrimidine kinase 19 161 1.1E-21 T 14-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 Tharo_0486 38d5ed4db339806c0c6d8e24f669ce56 299 Gene3D G3DSA:3.40.1190.20 9 292 1.8E-47 T 14-10-2018 IPR029056 Ribokinase-like Tharo_3015 52652df144b198d1be06bca4689e7ed7 145 TIGRFAM TIGR01068 thioredoxin: thioredoxin 46 141 1.3E-30 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Tharo_3015 52652df144b198d1be06bca4689e7ed7 145 ProSitePatterns PS00194 Thioredoxin family active site. 61 79 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 Tharo_3015 52652df144b198d1be06bca4689e7ed7 145 PRINTS PR00421 Thioredoxin family signature 108 119 1.8E-8 T 14-10-2018 Tharo_3015 52652df144b198d1be06bca4689e7ed7 145 PRINTS PR00421 Thioredoxin family signature 60 68 1.8E-8 T 14-10-2018 Tharo_3015 52652df144b198d1be06bca4689e7ed7 145 PRINTS PR00421 Thioredoxin family signature 68 77 1.8E-8 T 14-10-2018 Tharo_3015 52652df144b198d1be06bca4689e7ed7 145 Pfam PF00085 Thioredoxin 43 142 1.1E-27 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 Tharo_3015 52652df144b198d1be06bca4689e7ed7 145 Gene3D G3DSA:2.20.28.140 2 37 1.2E-13 T 14-10-2018 Tharo_3015 52652df144b198d1be06bca4689e7ed7 145 Gene3D G3DSA:3.40.30.10 38 143 8.7E-30 T 14-10-2018 Tharo_3015 52652df144b198d1be06bca4689e7ed7 145 SUPERFAMILY SSF52833 27 143 1.53E-36 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_1286 8d35ed0d5a7e9f65b8b6e9429535a8e1 169 Gene3D G3DSA:1.10.10.10 14 161 4.5E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1286 8d35ed0d5a7e9f65b8b6e9429535a8e1 169 SMART SM00347 43 143 2.5E-20 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_1286 8d35ed0d5a7e9f65b8b6e9429535a8e1 169 SUPERFAMILY SSF46785 18 158 4.39E-33 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1286 8d35ed0d5a7e9f65b8b6e9429535a8e1 169 Pfam PF01047 MarR family 50 107 2.6E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_1286 8d35ed0d5a7e9f65b8b6e9429535a8e1 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 99 8.0E-16 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_1286 8d35ed0d5a7e9f65b8b6e9429535a8e1 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 103 119 8.0E-16 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_1286 8d35ed0d5a7e9f65b8b6e9429535a8e1 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 83 8.0E-16 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_1286 8d35ed0d5a7e9f65b8b6e9429535a8e1 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 133 153 8.0E-16 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_0117 2c11f4ccdbf50799a4910d4e08a41c52 466 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 78 4.0E-19 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Tharo_0117 2c11f4ccdbf50799a4910d4e08a41c52 466 SUPERFAMILY SSF52540 82 353 1.04E-88 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0117 2c11f4ccdbf50799a4910d4e08a41c52 466 SUPERFAMILY SSF47917 350 465 3.14E-54 T 14-10-2018 Tharo_0117 2c11f4ccdbf50799a4910d4e08a41c52 466 Gene3D G3DSA:2.40.10.170 1 80 4.9E-28 T 14-10-2018 Tharo_0117 2c11f4ccdbf50799a4910d4e08a41c52 466 SMART SM00382 147 410 9.0E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0117 2c11f4ccdbf50799a4910d4e08a41c52 466 Gene3D G3DSA:1.10.1140.10 350 466 4.0E-58 T 14-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Tharo_0117 2c11f4ccdbf50799a4910d4e08a41c52 466 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 338 347 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Tharo_0117 2c11f4ccdbf50799a4910d4e08a41c52 466 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 135 347 1.1E-62 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Tharo_0117 2c11f4ccdbf50799a4910d4e08a41c52 466 Gene3D G3DSA:3.40.50.300 81 349 1.6E-111 T 14-10-2018 Tharo_0117 2c11f4ccdbf50799a4910d4e08a41c52 466 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 465 56.273 T 14-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 Tharo_0117 2c11f4ccdbf50799a4910d4e08a41c52 466 SUPERFAMILY SSF50615 1 79 1.44E-24 T 14-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Tharo_0117 2c11f4ccdbf50799a4910d4e08a41c52 466 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 465 1.5E-249 T 14-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 Tharo_0924 136199de9e36c231c70963d92d374b1b 356 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 181 335 3.0E-36 T 14-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 Tharo_0924 136199de9e36c231c70963d92d374b1b 356 Gene3D G3DSA:3.40.50.2000 5 341 2.1E-115 T 14-10-2018 Tharo_0924 136199de9e36c231c70963d92d374b1b 356 SUPERFAMILY SSF53756 2 351 3.35E-124 T 14-10-2018 Tharo_0924 136199de9e36c231c70963d92d374b1b 356 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 1 346 1.9E-106 T 14-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_0924 136199de9e36c231c70963d92d374b1b 356 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 4 351 36.869 T 14-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_0924 136199de9e36c231c70963d92d374b1b 356 Gene3D G3DSA:3.40.50.2000 158 335 2.1E-115 T 14-10-2018 Tharo_0924 136199de9e36c231c70963d92d374b1b 356 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 5 141 3.7E-35 T 14-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_3098 ef9d277809bd90173ceb7053423e0d7d 234 Pfam PF00005 ABC transporter 19 163 1.1E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_3098 ef9d277809bd90173ceb7053423e0d7d 234 Gene3D G3DSA:3.40.50.300 1 234 9.7E-61 T 14-10-2018 Tharo_3098 ef9d277809bd90173ceb7053423e0d7d 234 SMART SM00382 28 234 2.0E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_3098 ef9d277809bd90173ceb7053423e0d7d 234 SUPERFAMILY SSF52540 3 229 1.6E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3098 ef9d277809bd90173ceb7053423e0d7d 234 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_1985 0bc301d75a708ecdc8a9c312fbfe50e9 180 Gene3D G3DSA:3.40.50.700 3 177 1.4E-34 T 14-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily Tharo_1985 0bc301d75a708ecdc8a9c312fbfe50e9 180 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 15 163 9.5E-27 T 14-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1985 0bc301d75a708ecdc8a9c312fbfe50e9 180 SUPERFAMILY SSF56770 4 179 3.53E-36 T 14-10-2018 Tharo_2037 7eaf163edb842847e07f3c79a9d63f8d 459 Gene3D G3DSA:3.40.640.10 78 360 2.4E-142 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_2037 7eaf163edb842847e07f3c79a9d63f8d 459 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 28 453 1.3E-150 T 14-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 Tharo_2037 7eaf163edb842847e07f3c79a9d63f8d 459 Gene3D G3DSA:3.90.1150.10 27 447 2.4E-142 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_2037 7eaf163edb842847e07f3c79a9d63f8d 459 Pfam PF00202 Aminotransferase class-III 42 449 1.4E-103 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Tharo_2037 7eaf163edb842847e07f3c79a9d63f8d 459 SUPERFAMILY SSF53383 26 454 1.12E-116 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_2037 7eaf163edb842847e07f3c79a9d63f8d 459 PIRSF PIRSF000521 33 457 2.5E-24 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Tharo_3289 66fa1324667a4ce76d768a09c4be12e4 444 Pfam PF00271 Helicase conserved C-terminal domain 234 340 1.5E-30 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_3289 66fa1324667a4ce76d768a09c4be12e4 444 SMART SM00487 20 222 1.8E-58 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Tharo_3289 66fa1324667a4ce76d768a09c4be12e4 444 SUPERFAMILY SSF52540 73 361 1.51E-71 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3289 66fa1324667a4ce76d768a09c4be12e4 444 Gene3D G3DSA:3.40.50.300 1 211 2.6E-76 T 14-10-2018 Tharo_3289 66fa1324667a4ce76d768a09c4be12e4 444 SMART SM00490 259 340 7.3E-34 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_3289 66fa1324667a4ce76d768a09c4be12e4 444 Pfam PF00270 DEAD/DEAH box helicase 25 190 3.4E-49 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Tharo_3289 66fa1324667a4ce76d768a09c4be12e4 444 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 153 161 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site Tharo_3289 66fa1324667a4ce76d768a09c4be12e4 444 Gene3D G3DSA:3.40.50.300 215 378 6.0E-50 T 14-10-2018 Tharo_2398 22b496476e5ebc90978611868385cf71 314 SUPERFAMILY SSF53335 23 288 4.69E-32 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_2398 22b496476e5ebc90978611868385cf71 314 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 16 288 26.285 T 14-10-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00780+2.1.1.197|MetaCyc: PWY-6519 Tharo_2398 22b496476e5ebc90978611868385cf71 314 Gene3D G3DSA:3.40.50.150 3 209 2.8E-29 T 14-10-2018 Tharo_2398 22b496476e5ebc90978611868385cf71 314 Pfam PF08241 Methyltransferase domain 61 172 2.6E-14 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 Tharo_1609 dbd7563d23da18f9fc494b8f04508436 178 Gene3D G3DSA:1.10.10.880 1 62 2.3E-13 T 14-10-2018 IPR036147 Anti sigma-E protein RseA, N-terminal domain superfamily GO:0016989 Tharo_1609 dbd7563d23da18f9fc494b8f04508436 178 SUPERFAMILY SSF89069 1 62 5.23E-12 T 14-10-2018 IPR036147 Anti sigma-E protein RseA, N-terminal domain superfamily GO:0016989 Tharo_1609 dbd7563d23da18f9fc494b8f04508436 178 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 1 71 4.0E-16 T 14-10-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 Tharo_0254 f19a6f90227957959e3311522f345d2a 735 SMART SM00954 256 366 1.5E-62 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 Tharo_0254 f19a6f90227957959e3311522f345d2a 735 Pfam PF02824 TGS domain 409 468 1.4E-17 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 Tharo_0254 f19a6f90227957959e3311522f345d2a 735 SMART SM00471 62 174 2.3E-10 T 14-10-2018 IPR003607 HD/PDEase domain Tharo_0254 f19a6f90227957959e3311522f345d2a 735 Gene3D G3DSA:3.30.70.260 652 731 3.4E-14 T 14-10-2018 Tharo_0254 f19a6f90227957959e3311522f345d2a 735 Gene3D G3DSA:3.30.460.10 214 346 3.7E-43 T 14-10-2018 Tharo_0254 f19a6f90227957959e3311522f345d2a 735 Pfam PF13328 HD domain 47 196 8.5E-51 T 14-10-2018 IPR003607 HD/PDEase domain Tharo_0254 f19a6f90227957959e3311522f345d2a 735 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 47 725 1.4E-226 T 14-10-2018 IPR004811 RelA/SpoT family GO:0015969 Tharo_0254 f19a6f90227957959e3311522f345d2a 735 Gene3D G3DSA:1.10.3210.10 21 211 2.0E-76 T 14-10-2018 Tharo_0254 f19a6f90227957959e3311522f345d2a 735 SUPERFAMILY SSF55021 651 726 1.8E-9 T 14-10-2018 Tharo_0254 f19a6f90227957959e3311522f345d2a 735 Gene3D G3DSA:3.10.20.30 402 475 2.5E-30 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Tharo_0254 f19a6f90227957959e3311522f345d2a 735 SUPERFAMILY SSF109604 27 210 6.28E-69 T 14-10-2018 Tharo_0254 f19a6f90227957959e3311522f345d2a 735 Pfam PF04607 Region found in RelA / SpoT proteins 256 366 4.1E-33 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 Tharo_0254 f19a6f90227957959e3311522f345d2a 735 SUPERFAMILY SSF81271 396 468 2.4E-21 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 Tharo_0254 f19a6f90227957959e3311522f345d2a 735 SUPERFAMILY SSF81301 202 413 1.57E-61 T 14-10-2018 Tharo_0254 f19a6f90227957959e3311522f345d2a 735 Pfam PF13291 ACT domain 651 727 6.7E-18 T 14-10-2018 IPR002912 ACT domain Tharo_0071 eb598102dc6b78f4709311fa318f3a7e 549 Pfam PF00361 Proton-conducting membrane transporter 136 364 8.4E-22 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1879 cd566a854235da7c7931c33b7217178c 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.4E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_1879 cd566a854235da7c7931c33b7217178c 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.4E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_1879 cd566a854235da7c7931c33b7217178c 219 Gene3D G3DSA:1.10.357.10 58 193 7.8E-15 T 14-10-2018 Tharo_1879 cd566a854235da7c7931c33b7217178c 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 4.7E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_1879 cd566a854235da7c7931c33b7217178c 219 Gene3D G3DSA:1.10.10.60 3 57 1.5E-19 T 14-10-2018 Tharo_1879 cd566a854235da7c7931c33b7217178c 219 SUPERFAMILY SSF46689 8 87 3.9E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_1879 cd566a854235da7c7931c33b7217178c 219 SUPERFAMILY SSF48498 83 189 1.22E-7 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Tharo_1474 52605e0e87eac3d535ec57b7b4284390 98 Pfam PF13511 Domain of unknown function (DUF4124) 3 70 1.4E-5 T 14-10-2018 IPR025392 Domain of unknown function DUF4124 Tharo_3167 a9619006a17281bfa36931af63182346 979 SUPERFAMILY SSF52540 68 436 1.64E-6 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3167 a9619006a17281bfa36931af63182346 979 SMART SM00487 38 297 0.0034 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Tharo_3167 a9619006a17281bfa36931af63182346 979 SUPERFAMILY SSF52540 4 270 2.58E-13 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3167 a9619006a17281bfa36931af63182346 979 Gene3D G3DSA:3.40.50.300 288 444 3.7E-6 T 14-10-2018 Tharo_3167 a9619006a17281bfa36931af63182346 979 Pfam PF04851 Type III restriction enzyme, res subunit 4 268 1.4E-11 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 Tharo_0791 2f25eee4e8f025291df26acdbf9a6284 585 Pfam PF00999 Sodium/hydrogen exchanger family 14 390 2.3E-58 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Tharo_0791 2f25eee4e8f025291df26acdbf9a6284 585 SUPERFAMILY SSF51735 422 552 5.33E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_0791 2f25eee4e8f025291df26acdbf9a6284 585 Gene3D G3DSA:3.40.50.720 421 579 9.6E-41 T 14-10-2018 Tharo_0791 2f25eee4e8f025291df26acdbf9a6284 585 Pfam PF02254 TrkA-N domain 424 537 1.9E-25 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Tharo_0791 2f25eee4e8f025291df26acdbf9a6284 585 Gene3D G3DSA:1.20.1530.20 7 400 6.1E-78 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily Tharo_0955 4daae79318d8c85fce5f4fb50a7c6cac 70 Pfam PF11903 ParD-like antitoxin of type II bacterial toxin-antitoxin system 4 62 2.4E-20 T 14-10-2018 IPR021831 ParD-like antitoxin of type II bacterial toxin-antitoxin system Tharo_0116 ee2865c4f12397811bf2620471b2710c 289 Gene3D G3DSA:1.10.287.80 6 285 7.0E-102 T 14-10-2018 Tharo_0116 ee2865c4f12397811bf2620471b2710c 289 Gene3D G3DSA:3.40.1380.10 62 208 7.0E-102 T 14-10-2018 Tharo_0116 ee2865c4f12397811bf2620471b2710c 289 PRINTS PR00126 ATP synthase gamma subunit signature 75 94 3.4E-36 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0116 ee2865c4f12397811bf2620471b2710c 289 PRINTS PR00126 ATP synthase gamma subunit signature 267 288 3.4E-36 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0116 ee2865c4f12397811bf2620471b2710c 289 PRINTS PR00126 ATP synthase gamma subunit signature 169 186 3.4E-36 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0116 ee2865c4f12397811bf2620471b2710c 289 PRINTS PR00126 ATP synthase gamma subunit signature 236 255 3.4E-36 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0116 ee2865c4f12397811bf2620471b2710c 289 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 289 4.0E-103 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0116 ee2865c4f12397811bf2620471b2710c 289 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 275 288 - T 14-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0116 ee2865c4f12397811bf2620471b2710c 289 SUPERFAMILY SSF52943 2 289 5.36E-90 T 14-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0116 ee2865c4f12397811bf2620471b2710c 289 Pfam PF00231 ATP synthase 5 288 5.8E-92 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0116 ee2865c4f12397811bf2620471b2710c 289 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 289 35.669 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 Pfam PF09078 CheY binding 179 241 3.6E-18 T 14-10-2018 IPR015162 CheY binding Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 402 538 2.2E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 SMART SM00073 3 100 2.5E-32 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 SMART SM00387 399 539 9.2E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 SMART SM01231 291 354 6.5E-20 T 14-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 Gene3D G3DSA:2.30.30.40 539 667 5.6E-36 T 14-10-2018 Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 SUPERFAMILY SSF55874 356 537 4.71E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 Gene3D G3DSA:2.40.50.180 562 626 5.6E-36 T 14-10-2018 Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 Gene3D G3DSA:1.20.120.160 1 139 2.7E-45 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 SMART SM00260 531 671 4.2E-30 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 Pfam PF01627 Hpt domain 5 102 2.0E-18 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 SUPERFAMILY SSF47226 3 124 2.83E-32 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 Gene3D G3DSA:3.30.565.10 355 538 2.9E-55 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 Gene3D G3DSA:1.10.287.560 291 354 2.2E-15 T 14-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 PRINTS PR00344 Bacterial sensor protein C-terminal signature 499 517 4.9E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 458 4.9E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 PRINTS PR00344 Bacterial sensor protein C-terminal signature 483 493 4.9E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 PRINTS PR00344 Bacterial sensor protein C-terminal signature 523 536 4.9E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 Pfam PF01584 CheW-like domain 544 670 5.8E-22 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 Gene3D G3DSA:3.30.70.400 166 242 1.7E-17 T 14-10-2018 IPR035891 CheY-binding domain of CheA Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 SUPERFAMILY SSF55052 178 242 2.54E-15 T 14-10-2018 IPR035891 CheY-binding domain of CheA Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 SUPERFAMILY SSF47384 292 355 4.32E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 SUPERFAMILY SSF50341 538 670 4.58E-28 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 Tharo_0397 59ad4a6c4a52094175f2c4b1a94f2320 701 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 291 354 9.6E-16 T 14-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 Tharo_0880 63d703e32a22c558ef57cca7d4446d72 230 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_0880 63d703e32a22c558ef57cca7d4446d72 230 Gene3D G3DSA:3.40.50.300 2 230 3.9E-64 T 14-10-2018 Tharo_0880 63d703e32a22c558ef57cca7d4446d72 230 SMART SM00382 32 219 5.2E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0880 63d703e32a22c558ef57cca7d4446d72 230 SUPERFAMILY SSF52540 4 228 4.11E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0880 63d703e32a22c558ef57cca7d4446d72 230 Pfam PF00005 ABC transporter 23 171 4.5E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_1293 0153c961554fcef8bf6972dd7ed68279 100 Pfam PF00037 4Fe-4S binding domain 74 94 9.9E-7 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_1293 0153c961554fcef8bf6972dd7ed68279 100 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 78 89 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_1293 0153c961554fcef8bf6972dd7ed68279 100 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 32 98 1.6E-25 T 14-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 Tharo_1293 0153c961554fcef8bf6972dd7ed68279 100 SUPERFAMILY SSF54862 22 98 1.22E-17 T 14-10-2018 Tharo_1293 0153c961554fcef8bf6972dd7ed68279 100 Gene3D G3DSA:3.30.70.20 43 100 3.3E-11 T 14-10-2018 Tharo_1884 d6652c58c16a6db9cdf153cbb389fe40 365 Gene3D G3DSA:3.40.50.1400 17 337 3.0E-99 T 14-10-2018 Tharo_1884 d6652c58c16a6db9cdf153cbb389fe40 365 Pfam PF00762 Ferrochelatase 17 337 1.5E-116 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 Tharo_1884 d6652c58c16a6db9cdf153cbb389fe40 365 TIGRFAM TIGR00109 hemH: ferrochelatase 15 337 1.9E-93 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 Tharo_1884 d6652c58c16a6db9cdf153cbb389fe40 365 Hamap MF_00323 Ferrochelatase [hemH]. 16 337 37.44 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 Tharo_1884 d6652c58c16a6db9cdf153cbb389fe40 365 ProSitePatterns PS00534 Ferrochelatase signature. 206 224 - T 14-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 Tharo_1884 d6652c58c16a6db9cdf153cbb389fe40 365 Gene3D G3DSA:3.40.50.1400 180 318 3.0E-99 T 14-10-2018 Tharo_1884 d6652c58c16a6db9cdf153cbb389fe40 365 SUPERFAMILY SSF53800 16 341 1.31E-110 T 14-10-2018 Tharo_0535 f9d9dea02b1a0de94ccceaa77465fcbc 210 Pfam PF05573 NosL 70 197 4.8E-27 T 14-10-2018 IPR008719 Nitrous oxide reductase accessory protein NosL Tharo_0535 f9d9dea02b1a0de94ccceaa77465fcbc 210 SUPERFAMILY SSF160387 91 208 2.28E-30 T 14-10-2018 Tharo_0535 f9d9dea02b1a0de94ccceaa77465fcbc 210 Gene3D G3DSA:3.30.70.2050 150 209 6.0E-10 T 14-10-2018 Tharo_2967 7ee0b6961718bfad4eeb65960ce70646 149 Hamap MF_01114 Regulatory protein RecX [recX]. 3 148 13.493 T 14-10-2018 IPR003783 Regulatory protein RecX GO:0006282 Tharo_2967 7ee0b6961718bfad4eeb65960ce70646 149 Pfam PF02631 RecX family 33 144 4.8E-28 T 14-10-2018 IPR003783 Regulatory protein RecX GO:0006282 Tharo_2967 7ee0b6961718bfad4eeb65960ce70646 149 Gene3D G3DSA:1.10.10.10 99 146 5.8E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2967 7ee0b6961718bfad4eeb65960ce70646 149 Gene3D G3DSA:1.10.10.10 5 50 4.6E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2967 7ee0b6961718bfad4eeb65960ce70646 149 Gene3D G3DSA:1.10.10.10 52 93 1.4E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_3249 ccbd6624defb7fb18950e0de54d521cb 482 SUPERFAMILY SSF56112 293 443 4.37E-16 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Tharo_3249 ccbd6624defb7fb18950e0de54d521cb 482 SUPERFAMILY SSF56112 53 181 1.17E-9 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Tharo_3249 ccbd6624defb7fb18950e0de54d521cb 482 Gene3D G3DSA:1.10.510.10 401 466 5.1E-8 T 14-10-2018 Tharo_3249 ccbd6624defb7fb18950e0de54d521cb 482 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 312 464 3.3E-10 T 14-10-2018 Tharo_2456 ec656591376d660f81631fd296d0f3ee 324 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 140 161 - T 14-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 Tharo_2456 ec656591376d660f81631fd296d0f3ee 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 86 6.4E-7 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Tharo_2456 ec656591376d660f81631fd296d0f3ee 324 SMART SM00829 11 322 1.9E-33 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Tharo_2456 ec656591376d660f81631fd296d0f3ee 324 Gene3D G3DSA:3.40.50.720 123 268 4.9E-117 T 14-10-2018 Tharo_2456 ec656591376d660f81631fd296d0f3ee 324 SUPERFAMILY SSF50129 3 144 3.5E-36 T 14-10-2018 IPR011032 GroES-like superfamily Tharo_2456 ec656591376d660f81631fd296d0f3ee 324 Gene3D G3DSA:3.90.180.10 12 318 4.9E-117 T 14-10-2018 Tharo_2456 ec656591376d660f81631fd296d0f3ee 324 SUPERFAMILY SSF51735 111 261 1.18E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_2456 ec656591376d660f81631fd296d0f3ee 324 Pfam PF00107 Zinc-binding dehydrogenase 151 254 8.3E-29 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Tharo_0300 ec0e6de3083810f3ebe838aa8a6329f0 164 Pfam PF04002 RadC-like JAB domain 44 162 4.3E-41 T 14-10-2018 IPR025657 RadC-like JAB domain Tharo_0300 ec0e6de3083810f3ebe838aa8a6329f0 164 TIGRFAM TIGR00608 radc: DNA repair protein RadC 27 164 7.4E-42 T 14-10-2018 IPR001405 Uncharacterised protein family UPF0758 Tharo_0300 ec0e6de3083810f3ebe838aa8a6329f0 164 SUPERFAMILY SSF102712 57 132 6.67E-5 T 14-10-2018 Tharo_0300 ec0e6de3083810f3ebe838aa8a6329f0 164 Gene3D G3DSA:3.40.140.10 42 164 2.3E-40 T 14-10-2018 Tharo_1237 33d1762d73ba9c1946a06fe21996cde6 289 Gene3D G3DSA:3.40.800.20 1 289 5.9E-114 T 14-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 Tharo_1237 33d1762d73ba9c1946a06fe21996cde6 289 SUPERFAMILY SSF52768 2 288 8.63E-99 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily Tharo_1237 33d1762d73ba9c1946a06fe21996cde6 289 PRINTS PR01270 Histone deacetylase superfamily signature 216 226 1.3E-17 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 Tharo_1237 33d1762d73ba9c1946a06fe21996cde6 289 PRINTS PR01270 Histone deacetylase superfamily signature 138 153 1.3E-17 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 Tharo_1237 33d1762d73ba9c1946a06fe21996cde6 289 PRINTS PR01270 Histone deacetylase superfamily signature 104 127 1.3E-17 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 Tharo_1237 33d1762d73ba9c1946a06fe21996cde6 289 Pfam PF00850 Histone deacetylase domain 2 285 9.7E-80 T 14-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 Tharo_2374 821d7f425f02344f55708a581cf0ed6a 196 SUPERFAMILY SSF53218 4 189 9.95E-50 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily Tharo_2374 821d7f425f02344f55708a581cf0ed6a 196 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 5 147 5.4E-39 T 14-10-2018 IPR001453 MoaB/Mog domain Tharo_2374 821d7f425f02344f55708a581cf0ed6a 196 SMART SM00852 8 154 5.6E-24 T 14-10-2018 IPR001453 MoaB/Mog domain Tharo_2374 821d7f425f02344f55708a581cf0ed6a 196 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 70 83 - T 14-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 Tharo_2374 821d7f425f02344f55708a581cf0ed6a 196 Pfam PF00994 Probable molybdopterin binding domain 9 147 1.4E-28 T 14-10-2018 IPR001453 MoaB/Mog domain Tharo_2374 821d7f425f02344f55708a581cf0ed6a 196 Gene3D G3DSA:3.40.980.10 3 196 1.6E-63 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily Tharo_3107 77a6337c8a19daf0b55b9a8e33edf705 113 Gene3D G3DSA:3.30.2310.20 4 106 1.3E-18 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_3107 77a6337c8a19daf0b55b9a8e33edf705 113 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 10 101 1.7E-16 T 14-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Tharo_3107 77a6337c8a19daf0b55b9a8e33edf705 113 SUPERFAMILY SSF143011 8 101 9.03E-7 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_0637 a861ad006a04577aac08a79666c17514 195 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 174 6.4E-65 T 14-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 Tharo_0637 a861ad006a04577aac08a79666c17514 195 SUPERFAMILY SSF54211 1 86 1.64E-34 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_0637 a861ad006a04577aac08a79666c17514 195 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 195 42.734 T 14-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 Tharo_0637 a861ad006a04577aac08a79666c17514 195 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 14-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 Tharo_0637 a861ad006a04577aac08a79666c17514 195 Gene3D G3DSA:3.30.230.40 90 195 1.3E-38 T 14-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 Tharo_0637 a861ad006a04577aac08a79666c17514 195 SUPERFAMILY SSF54211 88 178 3.64E-34 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_0637 a861ad006a04577aac08a79666c17514 195 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 14-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 Tharo_0637 a861ad006a04577aac08a79666c17514 195 Gene3D G3DSA:3.30.230.40 1 89 1.7E-37 T 14-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 Tharo_0532 1f14c30ce3a51136886cbb41238fee8e 141 Gene3D G3DSA:3.40.50.720 5 141 5.1E-45 T 14-10-2018 Tharo_0532 1f14c30ce3a51136886cbb41238fee8e 141 SUPERFAMILY SSF51735 10 138 2.4E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_0532 1f14c30ce3a51136886cbb41238fee8e 141 SMART SM00881 17 109 4.0E-27 T 14-10-2018 IPR003781 CoA-binding GO:0048037 Tharo_0532 1f14c30ce3a51136886cbb41238fee8e 141 Pfam PF13380 CoA binding domain 21 135 8.4E-43 T 14-10-2018 IPR003781 CoA-binding GO:0048037 Tharo_0091 184c88eecc2c7dede9e3cc0d6e58f820 252 Gene3D G3DSA:2.40.50.140 184 251 5.6E-5 T 14-10-2018 Tharo_0091 184c88eecc2c7dede9e3cc0d6e58f820 252 SUPERFAMILY SSF50249 145 249 1.03E-27 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_0091 184c88eecc2c7dede9e3cc0d6e58f820 252 Gene3D G3DSA:3.30.1490.70 3 162 6.4E-52 T 14-10-2018 Tharo_0091 184c88eecc2c7dede9e3cc0d6e58f820 252 Pfam PF14743 DNA ligase OB-like domain 184 249 6.9E-27 T 14-10-2018 IPR029319 DNA ligase, OB-like domain Tharo_0091 184c88eecc2c7dede9e3cc0d6e58f820 252 Gene3D G3DSA:3.30.470.30 23 123 6.4E-52 T 14-10-2018 Tharo_0091 184c88eecc2c7dede9e3cc0d6e58f820 252 SUPERFAMILY SSF56091 8 169 9.36E-35 T 14-10-2018 Tharo_0091 184c88eecc2c7dede9e3cc0d6e58f820 252 Pfam PF01068 ATP dependent DNA ligase domain 14 168 8.6E-7 T 14-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 Tharo_1740 800eb730d6070799aa6ac63002d4510f 823 SUPERFAMILY SSF52540 449 681 7.09E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1740 800eb730d6070799aa6ac63002d4510f 823 Pfam PF00176 SNF2 family N-terminal domain 254 520 2.1E-38 T 14-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 Tharo_1740 800eb730d6070799aa6ac63002d4510f 823 Gene3D G3DSA:3.40.50.300 457 704 3.0E-60 T 14-10-2018 Tharo_1740 800eb730d6070799aa6ac63002d4510f 823 Gene3D G3DSA:3.40.50.10810 209 429 5.4E-45 T 14-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily Tharo_1740 800eb730d6070799aa6ac63002d4510f 823 SMART SM00487 232 418 1.9E-26 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Tharo_1740 800eb730d6070799aa6ac63002d4510f 823 SMART SM00490 560 642 1.1E-22 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_1740 800eb730d6070799aa6ac63002d4510f 823 Pfam PF00271 Helicase conserved C-terminal domain 537 642 1.1E-17 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_1740 800eb730d6070799aa6ac63002d4510f 823 SUPERFAMILY SSF52540 218 447 1.21E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2946 f86b27484d188f6f355b53be32477a14 535 Gene3D G3DSA:3.90.226.10 275 535 1.4E-98 T 14-10-2018 Tharo_2946 f86b27484d188f6f355b53be32477a14 535 SUPERFAMILY SSF52096 22 267 3.02E-71 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_2946 f86b27484d188f6f355b53be32477a14 535 Gene3D G3DSA:3.90.226.10 1 271 9.0E-98 T 14-10-2018 Tharo_2946 f86b27484d188f6f355b53be32477a14 535 Pfam PF01039 Carboxyl transferase domain 48 525 3.9E-144 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 Tharo_2946 f86b27484d188f6f355b53be32477a14 535 SUPERFAMILY SSF52096 237 517 1.33E-81 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_0712 4f3150e7776d056b9614a16d9a2e6e49 192 TIGRFAM TIGR03748 conj_PilL: integrating conjugative element protein PilL, PFGI-1 class 54 157 3.6E-43 T 14-10-2018 IPR022260 Integrating conjugative element protein PilL, PFGI-1 Tharo_3212 80ee96926469bc46568e83e17c4a81e8 464 SUPERFAMILY SSF53335 269 431 4.71E-26 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_3212 80ee96926469bc46568e83e17c4a81e8 464 SUPERFAMILY SSF53790 11 240 5.38E-28 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Tharo_3212 80ee96926469bc46568e83e17c4a81e8 464 Gene3D G3DSA:3.40.50.150 267 463 1.1E-66 T 14-10-2018 Tharo_3212 80ee96926469bc46568e83e17c4a81e8 464 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 290 411 7.8E-36 T 14-10-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00860+2.1.1.196|MetaCyc: PWY-7377 Tharo_3212 80ee96926469bc46568e83e17c4a81e8 464 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 12 238 4.3E-44 T 14-10-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 Tharo_3212 80ee96926469bc46568e83e17c4a81e8 464 Gene3D G3DSA:3.40.1010.10 9 114 5.6E-11 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Tharo_3212 80ee96926469bc46568e83e17c4a81e8 464 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 293 407 2.2E-5 T 14-10-2018 Tharo_3212 80ee96926469bc46568e83e17c4a81e8 464 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 10 224 1.7E-23 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Tharo_2932 5e4c991e606601c9db27334510503aa2 565 SMART SM00382 371 547 1.5E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2932 5e4c991e606601c9db27334510503aa2 565 Pfam PF00005 ABC transporter 362 511 9.9E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_2932 5e4c991e606601c9db27334510503aa2 565 Pfam PF00664 ABC transporter transmembrane region 29 297 3.1E-36 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Tharo_2932 5e4c991e606601c9db27334510503aa2 565 ProSitePatterns PS00211 ABC transporters family signature. 483 497 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_2932 5e4c991e606601c9db27334510503aa2 565 SUPERFAMILY SSF90123 14 327 3.14E-65 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Tharo_2932 5e4c991e606601c9db27334510503aa2 565 Gene3D G3DSA:3.40.50.300 337 563 3.3E-72 T 14-10-2018 Tharo_2932 5e4c991e606601c9db27334510503aa2 565 SUPERFAMILY SSF52540 337 558 5.33E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2932 5e4c991e606601c9db27334510503aa2 565 Gene3D G3DSA:1.20.1560.10 13 324 1.7E-68 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Tharo_2512 d80b1bb5c878dbf816e7e8504d03cf40 172 Pfam PF01782 RimM N-terminal domain 4 90 1.2E-25 T 14-10-2018 IPR002676 RimM, N-terminal GO:0006364 Tharo_2512 d80b1bb5c878dbf816e7e8504d03cf40 172 Gene3D G3DSA:2.40.30.60 1 93 5.1E-27 T 14-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 Tharo_2512 d80b1bb5c878dbf816e7e8504d03cf40 172 SUPERFAMILY SSF50346 99 171 1.81E-18 T 14-10-2018 IPR011033 PRC-barrel-like superfamily Tharo_2512 d80b1bb5c878dbf816e7e8504d03cf40 172 Gene3D G3DSA:2.30.30.240 95 172 7.9E-27 T 14-10-2018 Tharo_2512 d80b1bb5c878dbf816e7e8504d03cf40 172 SUPERFAMILY SSF50447 1 92 7.77E-21 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Tharo_2512 d80b1bb5c878dbf816e7e8504d03cf40 172 Pfam PF05239 PRC-barrel domain 96 167 3.7E-6 T 14-10-2018 IPR027275 PRC-barrel domain Tharo_2512 d80b1bb5c878dbf816e7e8504d03cf40 172 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 1 171 1.8E-46 T 14-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 Tharo_2512 d80b1bb5c878dbf816e7e8504d03cf40 172 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 1 172 23.375 T 14-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 Tharo_3333 9c3ad05792da7418a79a0376ba3cd7e7 209 Gene3D G3DSA:3.90.280.10 1 202 2.6E-51 T 14-10-2018 IPR036610 PEBP-like superfamily Tharo_3333 9c3ad05792da7418a79a0376ba3cd7e7 209 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 26 199 6.0E-25 T 14-10-2018 IPR005247 YbhB/YbcL Tharo_3333 9c3ad05792da7418a79a0376ba3cd7e7 209 Pfam PF01161 Phosphatidylethanolamine-binding protein 31 201 8.7E-40 T 14-10-2018 IPR008914 Phosphatidylethanolamine-binding protein Tharo_3333 9c3ad05792da7418a79a0376ba3cd7e7 209 SUPERFAMILY SSF49777 1 203 3.27E-45 T 14-10-2018 IPR036610 PEBP-like superfamily Tharo_1595 19317ad15457f0a0fc2f8b3c742eeae3 218 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 185 2.1E-35 T 14-10-2018 Tharo_1595 19317ad15457f0a0fc2f8b3c742eeae3 218 Gene3D G3DSA:1.10.150.240 20 85 1.3E-52 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 Tharo_1595 19317ad15457f0a0fc2f8b3c742eeae3 218 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 85 179 8.4E-13 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Tharo_1595 19317ad15457f0a0fc2f8b3c742eeae3 218 SUPERFAMILY SSF56784 5 214 1.58E-60 T 14-10-2018 IPR036412 HAD-like superfamily Tharo_1595 19317ad15457f0a0fc2f8b3c742eeae3 218 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 123 182 7.6E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Tharo_1595 19317ad15457f0a0fc2f8b3c742eeae3 218 Gene3D G3DSA:3.40.50.1000 8 205 1.3E-52 T 14-10-2018 IPR023214 HAD superfamily Tharo_3129 91285f892c4110a17d45fb488e84e362 149 PRINTS PR01693 Cyanase signature 134 144 3.0E-25 T 14-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 Tharo_3129 91285f892c4110a17d45fb488e84e362 149 PRINTS PR01693 Cyanase signature 16 31 3.0E-25 T 14-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 Tharo_3129 91285f892c4110a17d45fb488e84e362 149 PRINTS PR01693 Cyanase signature 103 119 3.0E-25 T 14-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 Tharo_3129 91285f892c4110a17d45fb488e84e362 149 PRINTS PR01693 Cyanase signature 85 99 3.0E-25 T 14-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 Tharo_3129 91285f892c4110a17d45fb488e84e362 149 PRINTS PR01693 Cyanase signature 36 53 3.0E-25 T 14-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 Tharo_3129 91285f892c4110a17d45fb488e84e362 149 Hamap MF_00535 Cyanate hydratase [cynS]. 1 149 82.901 T 14-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 Tharo_3129 91285f892c4110a17d45fb488e84e362 149 Pfam PF02560 Cyanate lyase C-terminal domain 81 147 5.7E-35 T 14-10-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00910+4.2.1.104 Tharo_3129 91285f892c4110a17d45fb488e84e362 149 Gene3D G3DSA:1.10.260.40 2 82 1.0E-29 T 14-10-2018 Tharo_3129 91285f892c4110a17d45fb488e84e362 149 TIGRFAM TIGR00673 cynS: cyanase 5 149 8.3E-52 T 14-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 Tharo_3129 91285f892c4110a17d45fb488e84e362 149 SUPERFAMILY SSF55234 82 149 2.48E-30 T 14-10-2018 IPR036581 Cyanate lyase, C-terminal domain superfamily GO:0009439 KEGG: 00910+4.2.1.104 Tharo_3129 91285f892c4110a17d45fb488e84e362 149 PIRSF PIRSF001263 1 149 1.6E-49 T 14-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 Tharo_3129 91285f892c4110a17d45fb488e84e362 149 SMART SM01116 77 149 3.3E-51 T 14-10-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00910+4.2.1.104 Tharo_3129 91285f892c4110a17d45fb488e84e362 149 Gene3D G3DSA:3.30.1160.10 83 149 9.3E-34 T 14-10-2018 IPR036581 Cyanate lyase, C-terminal domain superfamily GO:0009439 KEGG: 00910+4.2.1.104 Tharo_3129 91285f892c4110a17d45fb488e84e362 149 SUPERFAMILY SSF47413 2 79 1.63E-19 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_2251 c13b31c40d9a946845f9253db8f7da39 192 Gene3D G3DSA:3.30.1330.200 14 169 1.2E-47 T 14-10-2018 IPR038592 CheD-like superfamily Tharo_2251 c13b31c40d9a946845f9253db8f7da39 192 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 12 164 27.232 T 14-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 Tharo_2251 c13b31c40d9a946845f9253db8f7da39 192 SUPERFAMILY SSF64438 17 164 3.02E-46 T 14-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic Tharo_2251 c13b31c40d9a946845f9253db8f7da39 192 Pfam PF03975 CheD chemotactic sensory transduction 58 159 1.8E-28 T 14-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 Tharo_2929 5cca5f6c62086717c56dc9e853161613 548 Pfam PF01565 FAD binding domain 55 195 5.9E-27 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Tharo_2929 5cca5f6c62086717c56dc9e853161613 548 Gene3D G3DSA:3.40.462.10 242 495 2.6E-43 T 14-10-2018 IPR016170 Cytokinin dehydrogenase, C-terminal domain superfamily KEGG: 00908+1.5.99.12 Tharo_2929 5cca5f6c62086717c56dc9e853161613 548 SUPERFAMILY SSF56176 4 239 2.1E-49 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Tharo_2929 5cca5f6c62086717c56dc9e853161613 548 Gene3D G3DSA:3.30.465.10 111 239 2.9E-50 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Tharo_2929 5cca5f6c62086717c56dc9e853161613 548 Gene3D G3DSA:3.30.43.10 1 110 2.1E-34 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 Tharo_2929 5cca5f6c62086717c56dc9e853161613 548 Gene3D G3DSA:1.10.45.10 496 547 2.2E-23 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 Tharo_2929 5cca5f6c62086717c56dc9e853161613 548 SUPERFAMILY SSF55103 313 546 7.19E-20 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 Tharo_2929 5cca5f6c62086717c56dc9e853161613 548 Pfam PF02913 FAD linked oxidases, C-terminal domain 404 535 4.4E-5 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 Tharo_1984 25cdd96573fac6e9f9ae030747354f0b 488 Gene3D G3DSA:1.10.645.10 15 463 1.0E-93 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1984 25cdd96573fac6e9f9ae030747354f0b 488 Pfam PF00374 Nickel-dependent hydrogenase 53 130 3.4E-17 T 14-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 Tharo_1984 25cdd96573fac6e9f9ae030747354f0b 488 Pfam PF00374 Nickel-dependent hydrogenase 301 463 1.2E-10 T 14-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 Tharo_1984 25cdd96573fac6e9f9ae030747354f0b 488 SUPERFAMILY SSF56762 14 463 1.18E-122 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1984 25cdd96573fac6e9f9ae030747354f0b 488 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 454 463 - T 14-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 Tharo_1984 25cdd96573fac6e9f9ae030747354f0b 488 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 53 78 - T 14-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 Tharo_1712 882f197157f029229fca0a2845f8e1d6 914 SUPERFAMILY SSF47384 670 752 4.32E-20 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_1712 882f197157f029229fca0a2845f8e1d6 914 PRINTS PR00344 Bacterial sensor protein C-terminal signature 893 906 6.3E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1712 882f197157f029229fca0a2845f8e1d6 914 PRINTS PR00344 Bacterial sensor protein C-terminal signature 869 887 6.3E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1712 882f197157f029229fca0a2845f8e1d6 914 PRINTS PR00344 Bacterial sensor protein C-terminal signature 835 849 6.3E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1712 882f197157f029229fca0a2845f8e1d6 914 SMART SM00388 684 751 7.7E-19 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1712 882f197157f029229fca0a2845f8e1d6 914 Gene3D G3DSA:3.30.565.10 756 909 3.8E-41 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1712 882f197157f029229fca0a2845f8e1d6 914 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 798 907 7.4E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1712 882f197157f029229fca0a2845f8e1d6 914 Gene3D G3DSA:1.10.287.130 668 753 3.6E-23 T 14-10-2018 Tharo_1712 882f197157f029229fca0a2845f8e1d6 914 SMART SM00387 797 909 4.9E-38 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1712 882f197157f029229fca0a2845f8e1d6 914 Pfam PF00512 His Kinase A (phospho-acceptor) domain 685 751 1.2E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1712 882f197157f029229fca0a2845f8e1d6 914 Gene3D G3DSA:1.20.1730.10 31 489 1.6E-10 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily Tharo_1712 882f197157f029229fca0a2845f8e1d6 914 SUPERFAMILY SSF55874 740 909 1.22E-44 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1303 21131a4fac524b78ea1fe94cb7301a17 377 Pfam PF00378 Enoyl-CoA hydratase/isomerase 54 232 3.3E-34 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Tharo_1303 21131a4fac524b78ea1fe94cb7301a17 377 Gene3D G3DSA:3.90.226.10 44 234 1.3E-38 T 14-10-2018 Tharo_1303 21131a4fac524b78ea1fe94cb7301a17 377 SUPERFAMILY SSF52096 52 344 3.13E-46 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_1303 21131a4fac524b78ea1fe94cb7301a17 377 TIGRFAM TIGR03200 dearomat_oah: 6-oxocyclohex-1-ene-1-carbonyl-CoA hydrolase 17 373 1.3E-223 T 14-10-2018 IPR017613 6-oxocyclohex-1-ene-1-carbonyl-CoA hydrolase KEGG: 00362+3.7.1.21 Tharo_2947 7a69fc8715f4bce84594346553d06299 402 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 394 3.0E-124 T 14-10-2018 IPR002155 Thiolase GO:0016747 Tharo_2947 7a69fc8715f4bce84594346553d06299 402 SUPERFAMILY SSF53901 274 394 8.96E-40 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_2947 7a69fc8715f4bce84594346553d06299 402 Gene3D G3DSA:3.40.47.10 127 392 6.9E-140 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_2947 7a69fc8715f4bce84594346553d06299 402 Pfam PF02803 Thiolase, C-terminal domain 274 394 2.0E-41 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 Tharo_2947 7a69fc8715f4bce84594346553d06299 402 SUPERFAMILY SSF53901 5 273 1.43E-76 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_2947 7a69fc8715f4bce84594346553d06299 402 ProSitePatterns PS00099 Thiolases active site. 377 390 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 Tharo_2947 7a69fc8715f4bce84594346553d06299 402 Pfam PF00108 Thiolase, N-terminal domain 5 265 3.2E-84 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 Tharo_2947 7a69fc8715f4bce84594346553d06299 402 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 Tharo_2947 7a69fc8715f4bce84594346553d06299 402 Gene3D G3DSA:3.40.47.10 7 279 6.9E-140 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_2947 7a69fc8715f4bce84594346553d06299 402 PIRSF PIRSF000429 1 397 3.3E-113 T 14-10-2018 IPR002155 Thiolase GO:0016747 Tharo_2012 0887da7b5c8f2f6b3176c0bcf13f5ddb 329 SUPERFAMILY SSF53756 119 315 1.18E-24 T 14-10-2018 Tharo_2012 0887da7b5c8f2f6b3176c0bcf13f5ddb 329 TIGRFAM TIGR04348 TIGR04348: putative glycosyltransferase, TIGR04348 family 5 320 1.1E-134 T 14-10-2018 IPR027627 Putative glycosyltransferase Tharo_2012 0887da7b5c8f2f6b3176c0bcf13f5ddb 329 Gene3D G3DSA:3.40.50.2000 117 296 3.9E-20 T 14-10-2018 Tharo_2012 0887da7b5c8f2f6b3176c0bcf13f5ddb 329 Pfam PF00534 Glycosyl transferases group 1 133 276 1.9E-14 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 Tharo_2335 ca4977ccbd7eb78353586b1e410ce2ba 142 Pfam PF00572 Ribosomal protein L13 15 138 7.1E-54 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 Tharo_2335 ca4977ccbd7eb78353586b1e410ce2ba 142 SUPERFAMILY SSF52161 1 140 2.75E-58 T 14-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 Tharo_2335 ca4977ccbd7eb78353586b1e410ce2ba 142 PIRSF PIRSF002181 1 142 9.2E-47 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 Tharo_2335 ca4977ccbd7eb78353586b1e410ce2ba 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 27.198 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 Tharo_2335 ca4977ccbd7eb78353586b1e410ce2ba 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 141 3.2E-60 T 14-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2335 ca4977ccbd7eb78353586b1e410ce2ba 142 Gene3D G3DSA:3.90.1180.10 1 142 4.0E-60 T 14-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 Tharo_0875 a9aedbfd14a672f9d43bb0e55109b95b 610 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 435 594 1.9E-45 T 14-10-2018 IPR000160 GGDEF domain Tharo_0875 a9aedbfd14a672f9d43bb0e55109b95b 610 Gene3D G3DSA:3.30.70.270 431 601 9.9E-61 T 14-10-2018 Tharo_0875 a9aedbfd14a672f9d43bb0e55109b95b 610 SMART SM00267 425 597 1.1E-69 T 14-10-2018 IPR000160 GGDEF domain Tharo_0875 a9aedbfd14a672f9d43bb0e55109b95b 610 SUPERFAMILY SSF55073 441 598 3.3E-52 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_0875 a9aedbfd14a672f9d43bb0e55109b95b 610 SUPERFAMILY SSF55785 300 423 9.34E-20 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_0875 a9aedbfd14a672f9d43bb0e55109b95b 610 Pfam PF05231 MASE1 25 290 3.1E-14 T 14-10-2018 IPR007895 MASE1 Tharo_0875 a9aedbfd14a672f9d43bb0e55109b95b 610 SMART SM00091 310 376 3.0E-6 T 14-10-2018 IPR000014 PAS domain Tharo_0875 a9aedbfd14a672f9d43bb0e55109b95b 610 Gene3D G3DSA:3.30.450.20 300 430 1.4E-19 T 14-10-2018 Tharo_0875 a9aedbfd14a672f9d43bb0e55109b95b 610 Pfam PF00990 Diguanylate cyclase, GGDEF domain 436 593 1.1E-51 T 14-10-2018 IPR000160 GGDEF domain Tharo_0875 a9aedbfd14a672f9d43bb0e55109b95b 610 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 306 431 1.5E-19 T 14-10-2018 IPR000014 PAS domain Tharo_0875 a9aedbfd14a672f9d43bb0e55109b95b 610 Pfam PF13426 PAS domain 323 424 8.2E-12 T 14-10-2018 IPR000014 PAS domain Tharo_0475 fd2ab1dea256745f9bbdf92dae8e2901 274 PIRSF PIRSF000193 1 270 3.0E-63 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 Tharo_0475 fd2ab1dea256745f9bbdf92dae8e2901 274 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 163 266 2.0E-31 T 14-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 Tharo_0475 fd2ab1dea256745f9bbdf92dae8e2901 274 Gene3D G3DSA:1.10.3730.10 165 271 2.1E-36 T 14-10-2018 Tharo_0475 fd2ab1dea256745f9bbdf92dae8e2901 274 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 267 1.3E-72 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 Tharo_0475 fd2ab1dea256745f9bbdf92dae8e2901 274 SUPERFAMILY SSF48179 162 270 2.38E-30 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Tharo_0475 fd2ab1dea256745f9bbdf92dae8e2901 274 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 267 25.205 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 Tharo_0475 fd2ab1dea256745f9bbdf92dae8e2901 274 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 95 3.2E-16 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal Tharo_0475 fd2ab1dea256745f9bbdf92dae8e2901 274 Gene3D G3DSA:3.40.50.720 1 164 7.2E-42 T 14-10-2018 Tharo_0475 fd2ab1dea256745f9bbdf92dae8e2901 274 SUPERFAMILY SSF51735 1 160 4.93E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1428 61cc530b5754e2e3ec4aa841654997b2 421 TIGRFAM TIGR03246 arg_catab_astC: succinylornithine transaminase family 7 401 2.6E-195 T 14-10-2018 IPR017652 Acetyl/Succinylornithine transaminase family, bacteria GO:0006520|GO:0008483|GO:0030170 Tharo_1428 61cc530b5754e2e3ec4aa841654997b2 421 Gene3D G3DSA:3.40.640.10 59 304 6.7E-145 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_1428 61cc530b5754e2e3ec4aa841654997b2 421 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 15 402 67.168 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 Tharo_1428 61cc530b5754e2e3ec4aa841654997b2 421 PIRSF PIRSF000521 28 157 1.3E-5 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Tharo_1428 61cc530b5754e2e3ec4aa841654997b2 421 PIRSF PIRSF000521 173 402 4.4E-27 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Tharo_1428 61cc530b5754e2e3ec4aa841654997b2 421 Pfam PF00202 Aminotransferase class-III 26 398 2.2E-116 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Tharo_1428 61cc530b5754e2e3ec4aa841654997b2 421 SUPERFAMILY SSF53383 16 399 1.26E-121 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_1428 61cc530b5754e2e3ec4aa841654997b2 421 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 222 259 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Tharo_1428 61cc530b5754e2e3ec4aa841654997b2 421 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 16 398 9.1E-147 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 Tharo_1428 61cc530b5754e2e3ec4aa841654997b2 421 Gene3D G3DSA:3.90.1150.10 25 392 6.7E-145 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_2082 a0d4141c461c08c383954e4a88c1e2b8 113 Gene3D G3DSA:3.10.20.30 1 113 1.6E-33 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Tharo_2082 a0d4141c461c08c383954e4a88c1e2b8 113 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 42 52 - T 14-10-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 Tharo_2082 a0d4141c461c08c383954e4a88c1e2b8 113 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 14 91 8.9E-13 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Tharo_2082 a0d4141c461c08c383954e4a88c1e2b8 113 SUPERFAMILY SSF54292 4 108 9.56E-31 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Tharo_2082 a0d4141c461c08c383954e4a88c1e2b8 113 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 3 110 1.7E-54 T 14-10-2018 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 Tharo_2082 a0d4141c461c08c383954e4a88c1e2b8 113 PRINTS PR00355 Adrenodoxin signature 42 52 3.3E-9 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 Tharo_2082 a0d4141c461c08c383954e4a88c1e2b8 113 PRINTS PR00355 Adrenodoxin signature 60 74 3.3E-9 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 Tharo_2082 a0d4141c461c08c383954e4a88c1e2b8 113 PRINTS PR00355 Adrenodoxin signature 83 91 3.3E-9 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 Tharo_0456 8bc07c4a21d170248cd17d981d49a9af 340 SUPERFAMILY SSF54292 2 89 2.1E-27 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Tharo_0456 8bc07c4a21d170248cd17d981d49a9af 340 PRINTS PR00410 Phenol hydroxylase reductase family signature 208 227 9.0E-25 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 Tharo_0456 8bc07c4a21d170248cd17d981d49a9af 340 PRINTS PR00410 Phenol hydroxylase reductase family signature 192 201 9.0E-25 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 Tharo_0456 8bc07c4a21d170248cd17d981d49a9af 340 PRINTS PR00410 Phenol hydroxylase reductase family signature 132 144 9.0E-25 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 Tharo_0456 8bc07c4a21d170248cd17d981d49a9af 340 PRINTS PR00410 Phenol hydroxylase reductase family signature 300 308 9.0E-25 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 Tharo_0456 8bc07c4a21d170248cd17d981d49a9af 340 PRINTS PR00410 Phenol hydroxylase reductase family signature 148 155 9.0E-25 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 Tharo_0456 8bc07c4a21d170248cd17d981d49a9af 340 PRINTS PR00410 Phenol hydroxylase reductase family signature 233 242 9.0E-25 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 Tharo_0456 8bc07c4a21d170248cd17d981d49a9af 340 Pfam PF00175 Oxidoreductase NAD-binding domain 209 314 9.2E-21 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 Tharo_0456 8bc07c4a21d170248cd17d981d49a9af 340 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 233 242 5.5E-5 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Tharo_0456 8bc07c4a21d170248cd17d981d49a9af 340 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 208 227 5.5E-5 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Tharo_0456 8bc07c4a21d170248cd17d981d49a9af 340 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 148 155 5.5E-5 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Tharo_0456 8bc07c4a21d170248cd17d981d49a9af 340 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 132 142 5.5E-5 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Tharo_0456 8bc07c4a21d170248cd17d981d49a9af 340 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 11 81 6.0E-14 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Tharo_0456 8bc07c4a21d170248cd17d981d49a9af 340 SUPERFAMILY SSF63380 102 199 6.99E-28 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Tharo_0456 8bc07c4a21d170248cd17d981d49a9af 340 Gene3D G3DSA:3.40.50.80 200 336 3.9E-31 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_0456 8bc07c4a21d170248cd17d981d49a9af 340 Gene3D G3DSA:3.10.20.30 1 94 4.8E-27 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Tharo_0456 8bc07c4a21d170248cd17d981d49a9af 340 Gene3D G3DSA:2.40.30.10 102 199 1.3E-28 T 14-10-2018 Tharo_0456 8bc07c4a21d170248cd17d981d49a9af 340 SUPERFAMILY SSF52343 201 335 6.68E-37 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_0456 8bc07c4a21d170248cd17d981d49a9af 340 Pfam PF00970 Oxidoreductase FAD-binding domain 105 197 6.4E-15 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 Tharo_0456 8bc07c4a21d170248cd17d981d49a9af 340 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Tharo_3274 c1b2262cf384cd1d981720da0bac11fa 204 SUPERFAMILY SSF63380 1 87 3.83E-18 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Tharo_3274 c1b2262cf384cd1d981720da0bac11fa 204 PIRSF PIRSF000498 1 204 9.6E-69 T 14-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Tharo_3274 c1b2262cf384cd1d981720da0bac11fa 204 Gene3D G3DSA:2.40.30.20 101 202 1.6E-35 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Tharo_3274 c1b2262cf384cd1d981720da0bac11fa 204 Gene3D G3DSA:2.40.30.20 1 88 1.9E-19 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Tharo_3274 c1b2262cf384cd1d981720da0bac11fa 204 SUPERFAMILY SSF63380 92 194 4.34E-34 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Tharo_3274 c1b2262cf384cd1d981720da0bac11fa 204 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 196 9.1E-56 T 14-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Tharo_3274 c1b2262cf384cd1d981720da0bac11fa 204 Pfam PF00677 Lumazine binding domain 3 86 4.3E-13 T 14-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Tharo_3274 c1b2262cf384cd1d981720da0bac11fa 204 Pfam PF00677 Lumazine binding domain 99 183 1.3E-25 T 14-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Tharo_1275 8208005f043867229390ef03c2daf341 772 SUPERFAMILY SSF56228 25 230 2.49E-48 T 14-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily Tharo_1275 8208005f043867229390ef03c2daf341 772 SMART SM00790 25 229 2.0E-66 T 14-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 Tharo_1275 8208005f043867229390ef03c2daf341 772 SUPERFAMILY SSF54285 705 772 2.09E-5 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp Tharo_1275 8208005f043867229390ef03c2daf341 772 Pfam PF02597 ThiS family 708 772 1.1E-5 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 Tharo_1275 8208005f043867229390ef03c2daf341 772 SUPERFAMILY SSF48310 248 686 1.57E-78 T 14-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 Tharo_1275 8208005f043867229390ef03c2daf341 772 Gene3D G3DSA:3.60.9.10 21 232 1.6E-49 T 14-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily Tharo_1275 8208005f043867229390ef03c2daf341 772 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 243 686 6.9E-91 T 14-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 Tharo_1275 8208005f043867229390ef03c2daf341 772 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 26 227 2.0E-46 T 14-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 Tharo_1275 8208005f043867229390ef03c2daf341 772 Gene3D G3DSA:1.10.569.10 365 494 1.4E-76 T 14-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 Tharo_1275 8208005f043867229390ef03c2daf341 772 Gene3D G3DSA:1.10.599.10 495 684 1.4E-76 T 14-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 Tharo_1343 0bcf77bb9f58dac1251560f38bd2190c 287 SUPERFAMILY SSF89550 12 285 3.34E-46 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Tharo_1343 0bcf77bb9f58dac1251560f38bd2190c 287 Gene3D G3DSA:3.20.20.140 15 260 3.9E-81 T 14-10-2018 Tharo_1343 0bcf77bb9f58dac1251560f38bd2190c 287 Gene3D G3DSA:1.10.150.650 107 179 3.9E-81 T 14-10-2018 Tharo_1343 0bcf77bb9f58dac1251560f38bd2190c 287 SMART SM00481 14 79 6.0E-15 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal Tharo_1343 0bcf77bb9f58dac1251560f38bd2190c 287 Pfam PF02811 PHP domain 15 120 5.7E-6 T 14-10-2018 IPR004013 PHP domain GO:0003824 Tharo_3269 cec69397f536acf5c38ce1385c7f284a 80 SUPERFAMILY SSF47413 7 65 1.05E-12 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_3269 cec69397f536acf5c38ce1385c7f284a 80 Gene3D G3DSA:1.10.260.40 1 74 5.2E-15 T 14-10-2018 Tharo_3269 cec69397f536acf5c38ce1385c7f284a 80 Pfam PF01381 Helix-turn-helix 14 65 4.5E-9 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_3269 cec69397f536acf5c38ce1385c7f284a 80 TIGRFAM TIGR03070 couple_hipB: transcriptional regulator, y4mF family 8 65 1.4E-25 T 14-10-2018 IPR017507 Transcription regulator, HipB-like Tharo_3269 cec69397f536acf5c38ce1385c7f284a 80 SMART SM00530 13 68 9.0E-7 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_2798 396df1e113e787291af54a39661c147c 125 Pfam PF07238 PilZ domain 6 106 1.5E-13 T 14-10-2018 IPR009875 PilZ domain GO:0035438 Tharo_2798 396df1e113e787291af54a39661c147c 125 SUPERFAMILY SSF141371 2 122 1.73E-28 T 14-10-2018 Tharo_2798 396df1e113e787291af54a39661c147c 125 Gene3D G3DSA:2.40.10.220 1 125 3.9E-36 T 14-10-2018 Tharo_2798 396df1e113e787291af54a39661c147c 125 PIRSF PIRSF028141 2 125 7.1E-32 T 14-10-2018 IPR027021 Cyclic di-GMP binding protein, PA4608 type Tharo_0929 a0e1422f553b5ddccc65e1aa9a929b72 381 SUPERFAMILY SSF55307 199 314 2.75E-35 T 14-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 Tharo_0929 a0e1422f553b5ddccc65e1aa9a929b72 381 Gene3D G3DSA:3.40.50.1440 11 312 7.8E-106 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 Tharo_0929 a0e1422f553b5ddccc65e1aa9a929b72 381 SMART SM00864 13 200 2.2E-102 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Tharo_0929 a0e1422f553b5ddccc65e1aa9a929b72 381 Pfam PF12327 FtsZ family, C-terminal domain 217 311 1.4E-27 T 14-10-2018 IPR024757 Cell division protein FtsZ, C-terminal Tharo_0929 a0e1422f553b5ddccc65e1aa9a929b72 381 SMART SM00865 202 320 8.0E-46 T 14-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 Tharo_0929 a0e1422f553b5ddccc65e1aa9a929b72 381 PRINTS PR00423 Cell division protein FtsZ signature 184 206 3.1E-44 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Tharo_0929 a0e1422f553b5ddccc65e1aa9a929b72 381 PRINTS PR00423 Cell division protein FtsZ signature 207 228 3.1E-44 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Tharo_0929 a0e1422f553b5ddccc65e1aa9a929b72 381 PRINTS PR00423 Cell division protein FtsZ signature 95 115 3.1E-44 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Tharo_0929 a0e1422f553b5ddccc65e1aa9a929b72 381 PRINTS PR00423 Cell division protein FtsZ signature 123 144 3.1E-44 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Tharo_0929 a0e1422f553b5ddccc65e1aa9a929b72 381 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 10 317 3.3E-112 T 14-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 Tharo_0929 a0e1422f553b5ddccc65e1aa9a929b72 381 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 168 5.8E-35 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Tharo_0929 a0e1422f553b5ddccc65e1aa9a929b72 381 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 329 34.097 T 14-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 Tharo_0929 a0e1422f553b5ddccc65e1aa9a929b72 381 SUPERFAMILY SSF52490 13 203 5.49E-63 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 Tharo_0416 d4270c4f175796a8daa46c296daca42e 464 Gene3D G3DSA:1.10.150.130 123 234 1.7E-8 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Tharo_0416 d4270c4f175796a8daa46c296daca42e 464 Pfam PF13356 Arm DNA-binding domain 10 98 8.5E-14 T 14-10-2018 IPR025166 Integrase, DNA-binding domain Tharo_0416 d4270c4f175796a8daa46c296daca42e 464 SUPERFAMILY SSF56349 124 435 1.85E-30 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Tharo_0416 d4270c4f175796a8daa46c296daca42e 464 Gene3D G3DSA:3.30.160.390 8 121 1.1E-12 T 14-10-2018 IPR038488 Integrase, DNA-binding domain superfamily Tharo_0416 d4270c4f175796a8daa46c296daca42e 464 Pfam PF00589 Phage integrase family 263 413 2.5E-9 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Tharo_0416 d4270c4f175796a8daa46c296daca42e 464 Gene3D G3DSA:1.10.443.10 239 428 4.5E-12 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Tharo_0492 9afdcc61c14e5c310cf0be55684e48dd 277 SUPERFAMILY SSF51735 101 273 5.42E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_0492 9afdcc61c14e5c310cf0be55684e48dd 277 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 119 195 1.5E-8 T 14-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase Tharo_0492 9afdcc61c14e5c310cf0be55684e48dd 277 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 4 272 1.8E-81 T 14-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 Tharo_0492 9afdcc61c14e5c310cf0be55684e48dd 277 Gene3D G3DSA:3.40.50.10860 4 258 2.4E-80 T 14-10-2018 Tharo_0492 9afdcc61c14e5c310cf0be55684e48dd 277 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 6 88 1.9E-24 T 14-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 Tharo_0492 9afdcc61c14e5c310cf0be55684e48dd 277 Gene3D G3DSA:3.40.50.720 115 239 2.4E-80 T 14-10-2018 Tharo_0492 9afdcc61c14e5c310cf0be55684e48dd 277 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 1 276 31.331 T 14-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 Tharo_0492 9afdcc61c14e5c310cf0be55684e48dd 277 SUPERFAMILY SSF53223 2 100 8.63E-31 T 14-10-2018 Tharo_0976 ba9cc543ac7a36cb388a22873c3478e5 338 Gene3D G3DSA:3.40.190.10 203 293 1.4E-7 T 14-10-2018 Tharo_0976 ba9cc543ac7a36cb388a22873c3478e5 338 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 40 98 5.4E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0976 ba9cc543ac7a36cb388a22873c3478e5 338 SUPERFAMILY SSF46785 34 122 4.63E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0976 ba9cc543ac7a36cb388a22873c3478e5 338 Gene3D G3DSA:1.10.10.10 36 126 2.4E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0976 ba9cc543ac7a36cb388a22873c3478e5 338 SUPERFAMILY SSF53850 127 325 5.79E-25 T 14-10-2018 Tharo_0976 ba9cc543ac7a36cb388a22873c3478e5 338 Pfam PF03466 LysR substrate binding domain 157 326 4.1E-14 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_0976 ba9cc543ac7a36cb388a22873c3478e5 338 Gene3D G3DSA:3.40.190.10 156 202 1.4E-7 T 14-10-2018 Tharo_2321 34100562d4e038e906407090aec8abb2 159 Pfam PF03737 Aldolase/RraA 5 153 3.4E-47 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein Tharo_2321 34100562d4e038e906407090aec8abb2 159 TIGRFAM TIGR01935 NOT-MenG: RraA family 5 154 1.9E-66 T 14-10-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 Tharo_2321 34100562d4e038e906407090aec8abb2 159 Gene3D G3DSA:3.50.30.40 1 159 9.9E-69 T 14-10-2018 Tharo_2321 34100562d4e038e906407090aec8abb2 159 SUPERFAMILY SSF89562 3 157 1.31E-51 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily Tharo_1204 81a045e29769bb9e305b00ec4abd27a1 199 Pfam PF01025 GrpE 45 195 1.2E-44 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Tharo_1204 81a045e29769bb9e305b00ec4abd27a1 199 SUPERFAMILY SSF58014 46 137 4.05E-23 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 Tharo_1204 81a045e29769bb9e305b00ec4abd27a1 199 Hamap MF_01151 Protein GrpE [grpE]. 2 195 19.316 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Tharo_1204 81a045e29769bb9e305b00ec4abd27a1 199 Gene3D G3DSA:3.90.20.20 42 138 2.4E-25 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 Tharo_1204 81a045e29769bb9e305b00ec4abd27a1 199 SUPERFAMILY SSF51064 143 196 2.48E-17 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 Tharo_1204 81a045e29769bb9e305b00ec4abd27a1 199 PRINTS PR00773 GrpE protein signature 148 163 7.0E-26 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Tharo_1204 81a045e29769bb9e305b00ec4abd27a1 199 PRINTS PR00773 GrpE protein signature 174 193 7.0E-26 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Tharo_1204 81a045e29769bb9e305b00ec4abd27a1 199 PRINTS PR00773 GrpE protein signature 68 84 7.0E-26 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Tharo_1204 81a045e29769bb9e305b00ec4abd27a1 199 PRINTS PR00773 GrpE protein signature 96 111 7.0E-26 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Tharo_1204 81a045e29769bb9e305b00ec4abd27a1 199 Gene3D G3DSA:2.30.22.10 141 195 7.8E-22 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 Tharo_1204 81a045e29769bb9e305b00ec4abd27a1 199 ProSitePatterns PS01071 grpE protein signature. 151 193 - T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Tharo_1056 fd2c67a2aecc7443c80d9ef762b7ad7e 361 SUPERFAMILY SSF75620 12 353 3.4E-135 T 14-10-2018 Tharo_1056 fd2c67a2aecc7443c80d9ef762b7ad7e 361 SMART SM00937 63 178 9.8E-65 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 Tharo_1056 fd2c67a2aecc7443c80d9ef762b7ad7e 361 Gene3D G3DSA:3.30.70.1660 112 342 6.8E-98 T 14-10-2018 Tharo_1056 fd2c67a2aecc7443c80d9ef762b7ad7e 361 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 228 244 - T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Tharo_1056 fd2c67a2aecc7443c80d9ef762b7ad7e 361 Pfam PF03462 PCRF domain 14 203 1.0E-70 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 Tharo_1056 fd2c67a2aecc7443c80d9ef762b7ad7e 361 Pfam PF00472 RF-1 domain 211 321 5.4E-42 T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Tharo_1056 fd2c67a2aecc7443c80d9ef762b7ad7e 361 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 357 41.078 T 14-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 Tharo_1056 fd2c67a2aecc7443c80d9ef762b7ad7e 361 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 356 1.8E-162 T 14-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 Tharo_1056 fd2c67a2aecc7443c80d9ef762b7ad7e 361 Gene3D G3DSA:3.30.160.20 210 297 6.8E-98 T 14-10-2018 Tharo_3385 dea938523d1ce074cdcb5f750da5a44b 414 Pfam PF12323 Helix-turn-helix domain 1 48 3.2E-17 T 14-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain Tharo_3385 dea938523d1ce074cdcb5f750da5a44b 414 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 245 332 8.1E-7 T 14-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal Tharo_3385 dea938523d1ce074cdcb5f750da5a44b 414 Pfam PF01385 Probable transposase 165 276 5.1E-26 T 14-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 Tharo_3385 dea938523d1ce074cdcb5f750da5a44b 414 Pfam PF07282 Putative transposase DNA-binding domain 305 373 6.2E-22 T 14-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal Tharo_3338 e85e541ec8e68ff62d1a392dd1776868 378 PIRSF PIRSF000443 1 378 4.6E-134 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 Tharo_3338 e85e541ec8e68ff62d1a392dd1776868 378 Gene3D G3DSA:1.10.1740.110 187 292 1.7E-137 T 14-10-2018 Tharo_3338 e85e541ec8e68ff62d1a392dd1776868 378 SUPERFAMILY SSF53474 17 375 4.32E-105 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_3338 e85e541ec8e68ff62d1a392dd1776868 378 Pfam PF00561 alpha/beta hydrolase fold 51 361 5.6E-40 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_3338 e85e541ec8e68ff62d1a392dd1776868 378 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 14 374 29.67 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 Tharo_3338 e85e541ec8e68ff62d1a392dd1776868 378 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 22 371 4.7E-139 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 Tharo_3338 e85e541ec8e68ff62d1a392dd1776868 378 Gene3D G3DSA:3.40.50.1820 26 362 1.7E-137 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_3032 56578e3a0f5585c47ab4bfb6166f0227 727 SUPERFAMILY SSF52210 310 472 8.63E-32 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_3032 56578e3a0f5585c47ab4bfb6166f0227 727 Gene3D G3DSA:3.30.1490.20 526 604 2.5E-77 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Tharo_3032 56578e3a0f5585c47ab4bfb6166f0227 727 SMART SM00881 20 115 1.9E-33 T 14-10-2018 IPR003781 CoA-binding GO:0048037 Tharo_3032 56578e3a0f5585c47ab4bfb6166f0227 727 Gene3D G3DSA:3.40.50.261 308 477 3.8E-40 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_3032 56578e3a0f5585c47ab4bfb6166f0227 727 SUPERFAMILY SSF52210 147 299 2.49E-34 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_3032 56578e3a0f5585c47ab4bfb6166f0227 727 SUPERFAMILY SSF51735 18 145 1.77E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_3032 56578e3a0f5585c47ab4bfb6166f0227 727 Gene3D G3DSA:3.30.470.20 508 718 2.5E-77 T 14-10-2018 Tharo_3032 56578e3a0f5585c47ab4bfb6166f0227 727 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 165 301 2.5E-45 T 14-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain Tharo_3032 56578e3a0f5585c47ab4bfb6166f0227 727 Pfam PF13380 CoA binding domain 25 147 7.4E-23 T 14-10-2018 IPR003781 CoA-binding GO:0048037 Tharo_3032 56578e3a0f5585c47ab4bfb6166f0227 727 SUPERFAMILY SSF56059 507 721 3.32E-40 T 14-10-2018 Tharo_3032 56578e3a0f5585c47ab4bfb6166f0227 727 Pfam PF13549 ATP-grasp domain 503 720 2.8E-70 T 14-10-2018 Tharo_3032 56578e3a0f5585c47ab4bfb6166f0227 727 Gene3D G3DSA:3.40.50.720 15 144 1.3E-42 T 14-10-2018 Tharo_3032 56578e3a0f5585c47ab4bfb6166f0227 727 Gene3D G3DSA:3.40.50.261 146 304 7.1E-45 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_2268 813431de0a32c66e7c202e0e2583f10a 272 SUPERFAMILY SSF53335 79 269 6.92E-54 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_2268 813431de0a32c66e7c202e0e2583f10a 272 Pfam PF01739 CheR methyltransferase, SAM binding domain 79 261 7.5E-55 T 14-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal Tharo_2268 813431de0a32c66e7c202e0e2583f10a 272 Gene3D G3DSA:3.40.50.150 77 271 1.2E-58 T 14-10-2018 Tharo_2268 813431de0a32c66e7c202e0e2583f10a 272 Gene3D G3DSA:1.10.155.10 1 76 1.2E-20 T 14-10-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily Tharo_2268 813431de0a32c66e7c202e0e2583f10a 272 PIRSF PIRSF000410 2 271 6.1E-91 T 14-10-2018 IPR026024 Chemotaxis protein methyltransferase CheR Tharo_2268 813431de0a32c66e7c202e0e2583f10a 272 SMART SM00138 10 271 7.7E-88 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_2268 813431de0a32c66e7c202e0e2583f10a 272 Pfam PF03705 CheR methyltransferase, all-alpha domain 12 59 3.7E-14 T 14-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal Tharo_2268 813431de0a32c66e7c202e0e2583f10a 272 SUPERFAMILY SSF47757 3 77 1.16E-18 T 14-10-2018 Tharo_2268 813431de0a32c66e7c202e0e2583f10a 272 PRINTS PR00996 Glutamate methyltransferase family signature 107 127 1.2E-41 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_2268 813431de0a32c66e7c202e0e2583f10a 272 PRINTS PR00996 Glutamate methyltransferase family signature 230 253 1.2E-41 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_2268 813431de0a32c66e7c202e0e2583f10a 272 PRINTS PR00996 Glutamate methyltransferase family signature 71 83 1.2E-41 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_2268 813431de0a32c66e7c202e0e2583f10a 272 PRINTS PR00996 Glutamate methyltransferase family signature 211 225 1.2E-41 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_2268 813431de0a32c66e7c202e0e2583f10a 272 PRINTS PR00996 Glutamate methyltransferase family signature 32 45 1.2E-41 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_2268 813431de0a32c66e7c202e0e2583f10a 272 PRINTS PR00996 Glutamate methyltransferase family signature 140 156 1.2E-41 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_2480 71fbe6fbe1ec96148b586041bec0defa 124 SMART SM00905 4 113 7.2E-32 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 Tharo_2480 71fbe6fbe1ec96148b586041bec0defa 124 TIGRFAM TIGR00526 folB_dom: FolB domain 1 115 4.4E-23 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 Tharo_2480 71fbe6fbe1ec96148b586041bec0defa 124 Pfam PF02152 Dihydroneopterin aldolase 4 111 8.1E-24 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 Tharo_2480 71fbe6fbe1ec96148b586041bec0defa 124 Gene3D G3DSA:3.30.1130.10 1 117 6.3E-30 T 14-10-2018 Tharo_2480 71fbe6fbe1ec96148b586041bec0defa 124 SUPERFAMILY SSF55620 1 115 6.12E-29 T 14-10-2018 Tharo_1751 e5080766406d22a82eeef14c7a341fc9 184 Gene3D G3DSA:3.30.70.3460 48 183 2.6E-33 T 14-10-2018 Tharo_2437 125046f1906ab92aa2a8f2e01d81c799 677 SUPERFAMILY SSF52540 25 414 4.47E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2437 125046f1906ab92aa2a8f2e01d81c799 677 SUPERFAMILY SSF52540 332 654 7.7E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2437 125046f1906ab92aa2a8f2e01d81c799 677 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 31 671 46.624 T 14-10-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 Tharo_2437 125046f1906ab92aa2a8f2e01d81c799 677 Pfam PF13538 UvrD-like helicase C-terminal domain 601 644 3.8E-13 T 14-10-2018 IPR027785 UvrD-like helicase C-terminal domain Tharo_2437 125046f1906ab92aa2a8f2e01d81c799 677 Pfam PF13604 AAA domain 197 370 7.6E-29 T 14-10-2018 Tharo_2437 125046f1906ab92aa2a8f2e01d81c799 677 Gene3D G3DSA:1.10.10.1020 17 145 2.9E-12 T 14-10-2018 Tharo_2437 125046f1906ab92aa2a8f2e01d81c799 677 TIGRFAM TIGR01447 recD: exodeoxyribonuclease V, alpha subunit 23 672 8.0E-154 T 14-10-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 Tharo_2437 125046f1906ab92aa2a8f2e01d81c799 677 Gene3D G3DSA:3.40.50.300 418 540 3.0E-14 T 14-10-2018 Tharo_2437 125046f1906ab92aa2a8f2e01d81c799 677 Gene3D G3DSA:3.40.50.300 541 656 9.1E-22 T 14-10-2018 Tharo_2437 125046f1906ab92aa2a8f2e01d81c799 677 Gene3D G3DSA:3.40.50.300 146 408 1.5E-66 T 14-10-2018 Tharo_2907 9e9236727296ecd509e58cfa849dd580 516 Gene3D G3DSA:1.10.45.10 473 516 4.4E-22 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 Tharo_2907 9e9236727296ecd509e58cfa849dd580 516 Gene3D G3DSA:3.40.462.10 243 472 2.1E-79 T 14-10-2018 IPR016170 Cytokinin dehydrogenase, C-terminal domain superfamily KEGG: 00908+1.5.99.12 Tharo_2907 9e9236727296ecd509e58cfa849dd580 516 SUPERFAMILY SSF55103 244 514 7.41E-45 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 Tharo_2907 9e9236727296ecd509e58cfa849dd580 516 Gene3D G3DSA:3.30.43.10 3 114 3.1E-36 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 Tharo_2907 9e9236727296ecd509e58cfa849dd580 516 Pfam PF02913 FAD linked oxidases, C-terminal domain 320 511 4.8E-13 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 Tharo_2907 9e9236727296ecd509e58cfa849dd580 516 Pfam PF01565 FAD binding domain 58 198 9.0E-28 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Tharo_2907 9e9236727296ecd509e58cfa849dd580 516 SUPERFAMILY SSF56176 10 242 1.03E-57 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Tharo_2907 9e9236727296ecd509e58cfa849dd580 516 Gene3D G3DSA:3.30.465.10 115 242 1.0E-56 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Tharo_0124 d6766c4d1def6b0d787530d36eefa6c5 444 SUPERFAMILY SSF47384 197 278 2.94E-19 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_0124 d6766c4d1def6b0d787530d36eefa6c5 444 Gene3D G3DSA:3.30.565.10 292 442 1.1E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_0124 d6766c4d1def6b0d787530d36eefa6c5 444 Pfam PF00512 His Kinase A (phospho-acceptor) domain 210 278 2.6E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_0124 d6766c4d1def6b0d787530d36eefa6c5 444 SUPERFAMILY SSF55874 268 437 3.54E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_0124 d6766c4d1def6b0d787530d36eefa6c5 444 Gene3D G3DSA:3.30.450.20 92 206 6.2E-6 T 14-10-2018 Tharo_0124 d6766c4d1def6b0d787530d36eefa6c5 444 SMART SM00388 210 278 4.8E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_0124 d6766c4d1def6b0d787530d36eefa6c5 444 SMART SM00387 322 438 9.7E-33 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_0124 d6766c4d1def6b0d787530d36eefa6c5 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 416 7.0E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_0124 d6766c4d1def6b0d787530d36eefa6c5 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 377 7.0E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_0124 d6766c4d1def6b0d787530d36eefa6c5 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 391 7.0E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_0124 d6766c4d1def6b0d787530d36eefa6c5 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 435 7.0E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_0124 d6766c4d1def6b0d787530d36eefa6c5 444 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 99 434 9.2E-117 T 14-10-2018 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 Tharo_0124 d6766c4d1def6b0d787530d36eefa6c5 444 SUPERFAMILY SSF55785 93 181 1.49E-6 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_0124 d6766c4d1def6b0d787530d36eefa6c5 444 Pfam PF11808 Domain of unknown function (DUF3329) 18 86 6.4E-8 T 14-10-2018 IPR021766 Phosphate regulon sensor protein PhoR GO:0000155|GO:0000160|GO:0004721 Tharo_0124 d6766c4d1def6b0d787530d36eefa6c5 444 Gene3D G3DSA:1.10.287.130 207 278 3.0E-21 T 14-10-2018 Tharo_0124 d6766c4d1def6b0d787530d36eefa6c5 444 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 324 436 7.3E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_3302 1d9bf45cbc83df31c7fadb0ffb7d4bfd 447 Gene3D G3DSA:1.10.285.10 403 447 6.1E-8 T 14-10-2018 Tharo_3302 1d9bf45cbc83df31c7fadb0ffb7d4bfd 447 PIRSF PIRSF000185 21 447 1.3E-111 T 14-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 Tharo_3302 1d9bf45cbc83df31c7fadb0ffb7d4bfd 447 SUPERFAMILY SSF51735 201 446 2.23E-74 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_3302 1d9bf45cbc83df31c7fadb0ffb7d4bfd 447 SUPERFAMILY SSF53223 5 195 5.12E-73 T 14-10-2018 Tharo_3302 1d9bf45cbc83df31c7fadb0ffb7d4bfd 447 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 121 134 - T 14-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Tharo_3302 1d9bf45cbc83df31c7fadb0ffb7d4bfd 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 234 254 4.2E-32 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Tharo_3302 1d9bf45cbc83df31c7fadb0ffb7d4bfd 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 113 127 4.2E-32 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Tharo_3302 1d9bf45cbc83df31c7fadb0ffb7d4bfd 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 371 382 4.2E-32 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Tharo_3302 1d9bf45cbc83df31c7fadb0ffb7d4bfd 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 192 214 4.2E-32 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Tharo_3302 1d9bf45cbc83df31c7fadb0ffb7d4bfd 447 SMART SM00839 203 445 3.6E-97 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Tharo_3302 1d9bf45cbc83df31c7fadb0ffb7d4bfd 447 Gene3D G3DSA:3.40.50.720 208 372 1.1E-166 T 14-10-2018 Tharo_3302 1d9bf45cbc83df31c7fadb0ffb7d4bfd 447 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 56 183 1.0E-50 T 14-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Tharo_3302 1d9bf45cbc83df31c7fadb0ffb7d4bfd 447 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 201 445 1.8E-84 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Tharo_3302 1d9bf45cbc83df31c7fadb0ffb7d4bfd 447 Gene3D G3DSA:3.40.50.10860 54 189 1.1E-166 T 14-10-2018 Tharo_3302 1d9bf45cbc83df31c7fadb0ffb7d4bfd 447 Gene3D G3DSA:1.10.285.10 7 383 1.1E-166 T 14-10-2018 Tharo_1662 7f098802770adbf0fd8a33bd25185434 314 SUPERFAMILY SSF52374 15 173 8.16E-35 T 14-10-2018 Tharo_1662 7f098802770adbf0fd8a33bd25185434 314 Gene3D G3DSA:2.40.30.30 186 312 1.9E-40 T 14-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 Tharo_1662 7f098802770adbf0fd8a33bd25185434 314 SMART SM00904 181 306 5.1E-62 T 14-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 Tharo_1662 7f098802770adbf0fd8a33bd25185434 314 Pfam PF06574 FAD synthetase 10 164 6.7E-53 T 14-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 Tharo_1662 7f098802770adbf0fd8a33bd25185434 314 PIRSF PIRSF004491 1 313 1.7E-105 T 14-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 Tharo_1662 7f098802770adbf0fd8a33bd25185434 314 Gene3D G3DSA:3.40.50.620 2 184 3.1E-61 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_1662 7f098802770adbf0fd8a33bd25185434 314 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 16 306 1.1E-97 T 14-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 Tharo_1662 7f098802770adbf0fd8a33bd25185434 314 SUPERFAMILY SSF82114 172 307 3.92E-42 T 14-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 Tharo_1662 7f098802770adbf0fd8a33bd25185434 314 Pfam PF01687 Riboflavin kinase 182 305 3.8E-39 T 14-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 Tharo_0861 65983466d981a34f738f0cd732fb764e 615 PIRSF PIRSF001348 1 614 5.2E-285 T 14-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 Tharo_0861 65983466d981a34f738f0cd732fb764e 615 Gene3D G3DSA:3.40.449.10 24 248 5.8E-267 T 14-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 Tharo_0861 65983466d981a34f738f0cd732fb764e 615 SUPERFAMILY SSF68923 15 248 1.31E-103 T 14-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 Tharo_0861 65983466d981a34f738f0cd732fb764e 615 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 249 606 1.2E-171 T 14-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 Tharo_0861 65983466d981a34f738f0cd732fb764e 615 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 273 281 - T 14-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 Tharo_0861 65983466d981a34f738f0cd732fb764e 615 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 24 245 5.6E-105 T 14-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 Tharo_0861 65983466d981a34f738f0cd732fb764e 615 Gene3D G3DSA:3.90.228.20 249 603 5.8E-267 T 14-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 Tharo_0861 65983466d981a34f738f0cd732fb764e 615 SUPERFAMILY SSF53795 249 610 2.52E-158 T 14-10-2018 Tharo_0861 65983466d981a34f738f0cd732fb764e 615 Gene3D G3DSA:2.170.8.10 60 409 5.8E-267 T 14-10-2018 Tharo_0861 65983466d981a34f738f0cd732fb764e 615 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 13 613 51.532 T 14-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 Tharo_1569 34538a38ed05a857b473d208431769fd 729 Pfam PF09334 tRNA synthetases class I (M) 5 414 8.8E-141 T 14-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_1569 34538a38ed05a857b473d208431769fd 729 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 23 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_1569 34538a38ed05a857b473d208431769fd 729 SUPERFAMILY SSF52374 2 402 7.84E-91 T 14-10-2018 Tharo_1569 34538a38ed05a857b473d208431769fd 729 Gene3D G3DSA:2.40.50.140 610 729 6.2E-30 T 14-10-2018 Tharo_1569 34538a38ed05a857b473d208431769fd 729 SUPERFAMILY SSF47323 407 566 1.7E-37 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_1569 34538a38ed05a857b473d208431769fd 729 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 588 729 9.6E-38 T 14-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Tharo_1569 34538a38ed05a857b473d208431769fd 729 Gene3D G3DSA:2.20.28.20 139 173 1.7E-139 T 14-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Tharo_1569 34538a38ed05a857b473d208431769fd 729 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 527 1.1E-157 T 14-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Tharo_1569 34538a38ed05a857b473d208431769fd 729 Gene3D G3DSA:1.10.730.10 398 556 4.1E-31 T 14-10-2018 Tharo_1569 34538a38ed05a857b473d208431769fd 729 SUPERFAMILY SSF50249 614 728 1.32E-26 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_1569 34538a38ed05a857b473d208431769fd 729 Hamap MF_00098 Methionine--tRNA ligase [metG]. 3 565 38.806 T 14-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Tharo_1569 34538a38ed05a857b473d208431769fd 729 Pfam PF01588 Putative tRNA binding domain 624 725 3.3E-19 T 14-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 Tharo_1569 34538a38ed05a857b473d208431769fd 729 Gene3D G3DSA:3.40.50.620 5 397 1.7E-139 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_1569 34538a38ed05a857b473d208431769fd 729 SUPERFAMILY SSF57770 139 173 1.1E-11 T 14-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Tharo_1569 34538a38ed05a857b473d208431769fd 729 PRINTS PR01041 Methionyl-tRNA synthetase signature 260 271 3.1E-23 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Tharo_1569 34538a38ed05a857b473d208431769fd 729 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 3.1E-23 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Tharo_1569 34538a38ed05a857b473d208431769fd 729 PRINTS PR01041 Methionyl-tRNA synthetase signature 308 323 3.1E-23 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Tharo_1569 34538a38ed05a857b473d208431769fd 729 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 3.1E-23 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Tharo_1569 34538a38ed05a857b473d208431769fd 729 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 3.1E-23 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Tharo_1569 34538a38ed05a857b473d208431769fd 729 PRINTS PR01041 Methionyl-tRNA synthetase signature 402 413 3.1E-23 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Tharo_2227 debd99b6a84915c884ccb0a90d058926 272 SUPERFAMILY SSF53474 4 269 3.41E-53 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_2227 debd99b6a84915c884ccb0a90d058926 272 Pfam PF00561 alpha/beta hydrolase fold 34 259 1.8E-23 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_2227 debd99b6a84915c884ccb0a90d058926 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 215 229 1.2E-11 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_2227 debd99b6a84915c884ccb0a90d058926 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 59 74 1.2E-11 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_2227 debd99b6a84915c884ccb0a90d058926 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 116 129 1.2E-11 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_2227 debd99b6a84915c884ccb0a90d058926 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 1.2E-11 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_2227 debd99b6a84915c884ccb0a90d058926 272 PRINTS PR00412 Epoxide hydrolase signature 59 74 3.4E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 Tharo_2227 debd99b6a84915c884ccb0a90d058926 272 PRINTS PR00412 Epoxide hydrolase signature 116 129 3.4E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 Tharo_2227 debd99b6a84915c884ccb0a90d058926 272 PRINTS PR00412 Epoxide hydrolase signature 249 271 3.4E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 Tharo_2227 debd99b6a84915c884ccb0a90d058926 272 Gene3D G3DSA:3.40.50.1820 4 270 7.0E-53 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_1150 a2504399081e9acdf1630831d37ba339 542 Pfam PF05977 Transmembrane secretion effector 17 535 2.1E-149 T 14-10-2018 IPR010290 Transmembrane secretion effector Tharo_1150 a2504399081e9acdf1630831d37ba339 542 SUPERFAMILY SSF103473 25 403 1.44E-44 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_1150 a2504399081e9acdf1630831d37ba339 542 Gene3D G3DSA:1.20.1250.20 2 403 1.7E-36 T 14-10-2018 Tharo_3157 5385d046135e27bd92193cd8f9211f0f 250 SUPERFAMILY SSF51735 7 249 1.59E-78 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_3157 5385d046135e27bd92193cd8f9211f0f 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 6.5E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3157 5385d046135e27bd92193cd8f9211f0f 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 6.5E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3157 5385d046135e27bd92193cd8f9211f0f 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.5E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3157 5385d046135e27bd92193cd8f9211f0f 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 6.5E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3157 5385d046135e27bd92193cd8f9211f0f 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 6.5E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3157 5385d046135e27bd92193cd8f9211f0f 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 248 2.0E-63 T 14-10-2018 Tharo_3157 5385d046135e27bd92193cd8f9211f0f 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 182 4.5E-4 T 14-10-2018 Tharo_3157 5385d046135e27bd92193cd8f9211f0f 250 Gene3D G3DSA:3.40.50.720 1 249 3.0E-80 T 14-10-2018 Tharo_3157 5385d046135e27bd92193cd8f9211f0f 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 2.6E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3157 5385d046135e27bd92193cd8f9211f0f 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.6E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2092 ad03cd65de6e2476d6c43cf3c10a727b 270 PRINTS PR01959 SuhB family inositol monophosphatase signature 107 126 5.3E-29 T 14-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 Tharo_2092 ad03cd65de6e2476d6c43cf3c10a727b 270 PRINTS PR01959 SuhB family inositol monophosphatase signature 159 185 5.3E-29 T 14-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 Tharo_2092 ad03cd65de6e2476d6c43cf3c10a727b 270 PRINTS PR01959 SuhB family inositol monophosphatase signature 17 39 5.3E-29 T 14-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 Tharo_2092 ad03cd65de6e2476d6c43cf3c10a727b 270 PRINTS PR01959 SuhB family inositol monophosphatase signature 201 213 5.3E-29 T 14-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 Tharo_2092 ad03cd65de6e2476d6c43cf3c10a727b 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 2.2E-63 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Tharo_2092 ad03cd65de6e2476d6c43cf3c10a727b 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 2.2E-63 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Tharo_2092 ad03cd65de6e2476d6c43cf3c10a727b 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 180 201 2.2E-63 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Tharo_2092 ad03cd65de6e2476d6c43cf3c10a727b 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 133 156 2.2E-63 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Tharo_2092 ad03cd65de6e2476d6c43cf3c10a727b 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 211 235 2.2E-63 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Tharo_2092 ad03cd65de6e2476d6c43cf3c10a727b 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 2.2E-63 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Tharo_2092 ad03cd65de6e2476d6c43cf3c10a727b 270 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 214 228 - T 14-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 Tharo_2092 ad03cd65de6e2476d6c43cf3c10a727b 270 Gene3D G3DSA:3.30.540.10 1 143 1.7E-50 T 14-10-2018 Tharo_2092 ad03cd65de6e2476d6c43cf3c10a727b 270 Pfam PF00459 Inositol monophosphatase family 2 254 5.3E-69 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Tharo_2092 ad03cd65de6e2476d6c43cf3c10a727b 270 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 84 97 - T 14-10-2018 IPR020583 Inositol monophosphatase, metal-binding site Tharo_2092 ad03cd65de6e2476d6c43cf3c10a727b 270 SUPERFAMILY SSF56655 1 265 1.05E-88 T 14-10-2018 Tharo_2092 ad03cd65de6e2476d6c43cf3c10a727b 270 Gene3D G3DSA:3.40.190.80 144 266 2.3E-38 T 14-10-2018 Tharo_1918 df7c0804b8df73d54229a5263af5468e 159 SUPERFAMILY SSF52833 2 157 2.12E-53 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_1918 df7c0804b8df73d54229a5263af5468e 159 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 9 156 8.1E-62 T 14-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1918 df7c0804b8df73d54229a5263af5468e 159 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 11 156 2.1E-50 T 14-10-2018 Tharo_1918 df7c0804b8df73d54229a5263af5468e 159 Gene3D G3DSA:1.10.10.1590 1 73 5.4E-25 T 14-10-2018 Tharo_1918 df7c0804b8df73d54229a5263af5468e 159 Gene3D G3DSA:3.40.30.10 74 159 3.4E-25 T 14-10-2018 Tharo_1918 df7c0804b8df73d54229a5263af5468e 159 PIRSF PIRSF000216 1 159 4.1E-57 T 14-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1918 df7c0804b8df73d54229a5263af5468e 159 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 113 131 - T 14-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1135 8b75ab0f4e9d0d4b1d6f1c265dc6ac6e 527 Gene3D G3DSA:3.90.226.10 1 527 3.3E-285 T 14-10-2018 Tharo_1135 8b75ab0f4e9d0d4b1d6f1c265dc6ac6e 527 TIGRFAM TIGR03222 benzo_boxC: benzoyl-CoA-dihydrodiol lyase 1 527 1.2E-291 T 14-10-2018 IPR017633 Benzoyl-CoA-dihydrodiol lyase KEGG: 00362+4.1.2.44|MetaCyc: PWY-1361 Tharo_1135 8b75ab0f4e9d0d4b1d6f1c265dc6ac6e 527 SUPERFAMILY SSF52096 277 514 2.43E-14 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_1135 8b75ab0f4e9d0d4b1d6f1c265dc6ac6e 527 Pfam PF00378 Enoyl-CoA hydratase/isomerase 26 214 4.5E-22 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Tharo_1135 8b75ab0f4e9d0d4b1d6f1c265dc6ac6e 527 Gene3D G3DSA:3.90.226.10 236 462 3.3E-285 T 14-10-2018 Tharo_1135 8b75ab0f4e9d0d4b1d6f1c265dc6ac6e 527 SUPERFAMILY SSF52096 2 218 1.96E-30 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_2950 12fef333d7ea02d332b0ad123ce52a87 607 SUPERFAMILY SSF53474 239 532 9.86E-44 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_2950 12fef333d7ea02d332b0ad123ce52a87 607 Pfam PF00561 alpha/beta hydrolase fold 285 525 4.2E-12 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_2950 12fef333d7ea02d332b0ad123ce52a87 607 TIGRFAM TIGR01838 PHA_synth_I: poly(R)-hydroxyalkanoic acid synthase, class I 68 598 7.2E-239 T 14-10-2018 IPR010963 Poly(R)-hydroxyalkanoic acid synthase, class I GO:0005737|GO:0016746|GO:0042619 Tharo_2950 12fef333d7ea02d332b0ad123ce52a87 607 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 109 281 2.7E-76 T 14-10-2018 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 Tharo_2199 e72ef62146ca9c48fe00cd21a25dd86e 358 SUPERFAMILY SSF51569 1 356 5.37E-71 T 14-10-2018 Tharo_2199 e72ef62146ca9c48fe00cd21a25dd86e 358 Gene3D G3DSA:3.20.20.70 1 357 9.8E-143 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_2199 e72ef62146ca9c48fe00cd21a25dd86e 358 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 14 355 5.4E-75 T 14-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 Tharo_2199 e72ef62146ca9c48fe00cd21a25dd86e 358 PIRSF PIRSF036915 1 358 3.3E-138 T 14-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 Tharo_2199 e72ef62146ca9c48fe00cd21a25dd86e 358 ProSitePatterns PS01054 Transaldolase signature 1. 40 48 - T 14-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 Tharo_2199 e72ef62146ca9c48fe00cd21a25dd86e 358 TIGRFAM TIGR00876 tal_mycobact: transaldolase 13 355 1.3E-101 T 14-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 Tharo_2199 e72ef62146ca9c48fe00cd21a25dd86e 358 ProSitePatterns PS00958 Transaldolase active site. 136 153 - T 14-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 Tharo_2199 e72ef62146ca9c48fe00cd21a25dd86e 358 Hamap MF_00493 Transaldolase [tal]. 1 358 131.595 T 14-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 Tharo_2407 b74a392a80f920e8cf5998bb2a9328a1 427 Pfam PF00696 Amino acid kinase family 15 253 1.7E-35 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Tharo_2407 b74a392a80f920e8cf5998bb2a9328a1 427 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 2 427 1.4E-168 T 14-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 Tharo_2407 b74a392a80f920e8cf5998bb2a9328a1 427 Gene3D G3DSA:3.40.1160.10 1 279 1.6E-82 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Tharo_2407 b74a392a80f920e8cf5998bb2a9328a1 427 Pfam PF00583 Acetyltransferase (GNAT) family 318 393 8.1E-10 T 14-10-2018 IPR000182 GNAT domain Tharo_2407 b74a392a80f920e8cf5998bb2a9328a1 427 SUPERFAMILY SSF55729 249 403 3.6E-21 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Tharo_2407 b74a392a80f920e8cf5998bb2a9328a1 427 PIRSF PIRSF000423 1 427 2.2E-183 T 14-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 Tharo_2407 b74a392a80f920e8cf5998bb2a9328a1 427 SUPERFAMILY SSF53633 2 278 5.63E-65 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Tharo_2407 b74a392a80f920e8cf5998bb2a9328a1 427 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 427 199.183 T 14-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 Tharo_2407 b74a392a80f920e8cf5998bb2a9328a1 427 Gene3D G3DSA:3.40.630.30 282 427 2.3E-39 T 14-10-2018 Tharo_0177 70524a59f0be508fce0743a298628df7 301 SUPERFAMILY SSF54909 133 249 1.61E-14 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel Tharo_0177 70524a59f0be508fce0743a298628df7 301 Pfam PF07110 EthD domain 143 237 5.2E-11 T 14-10-2018 IPR009799 EthD domain Tharo_0177 70524a59f0be508fce0743a298628df7 301 SUPERFAMILY SSF54909 9 99 4.02E-5 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel Tharo_0177 70524a59f0be508fce0743a298628df7 301 Gene3D G3DSA:3.30.70.100 124 234 3.4E-6 T 14-10-2018 Tharo_2354 8fb9643bd9ef02f60eb170d2dc5f7fc4 191 Pfam PF09835 Uncharacterized protein conserved in bacteria (DUF2062) 18 169 1.2E-38 T 14-10-2018 IPR018639 Domain of unknown function DUF2062 Tharo_0022 7f5459cbf280be3066bd5f2f5fc6ce38 442 Gene3D G3DSA:2.40.30.10 216 313 1.3E-13 T 14-10-2018 Tharo_0022 7f5459cbf280be3066bd5f2f5fc6ce38 442 Pfam PF08022 FAD-binding domain 237 313 4.3E-6 T 14-10-2018 IPR013112 FAD-binding 8 GO:0016491|GO:0055114 Tharo_0022 7f5459cbf280be3066bd5f2f5fc6ce38 442 Gene3D G3DSA:3.40.50.80 320 442 8.5E-21 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_0022 7f5459cbf280be3066bd5f2f5fc6ce38 442 PRINTS PR00409 Phthalate dioxygenase reductase family signature 407 415 1.2E-7 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Tharo_0022 7f5459cbf280be3066bd5f2f5fc6ce38 442 PRINTS PR00409 Phthalate dioxygenase reductase family signature 325 344 1.2E-7 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Tharo_0022 7f5459cbf280be3066bd5f2f5fc6ce38 442 PRINTS PR00409 Phthalate dioxygenase reductase family signature 303 317 1.2E-7 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Tharo_0022 7f5459cbf280be3066bd5f2f5fc6ce38 442 SUPERFAMILY SSF52343 322 439 2.88E-21 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_0022 7f5459cbf280be3066bd5f2f5fc6ce38 442 SUPERFAMILY SSF63380 230 315 2.65E-17 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Tharo_0022 7f5459cbf280be3066bd5f2f5fc6ce38 442 Pfam PF01794 Ferric reductase like transmembrane component 43 177 8.6E-18 T 14-10-2018 IPR013130 Ferric reductase transmembrane component-like domain Tharo_3447 2499bf02c68b5220c03495027dcc4cb7 1235 Pfam PF08401 Domain of unknown function (DUF1738) 227 347 1.6E-33 T 14-10-2018 IPR013610 Domain of unknown function DUF1738 Tharo_3447 2499bf02c68b5220c03495027dcc4cb7 1235 SMART SM00493 1075 1157 1.7E-5 T 14-10-2018 IPR006171 TOPRIM domain Tharo_3447 2499bf02c68b5220c03495027dcc4cb7 1235 Pfam PF13662 Toprim domain 1077 1152 5.1E-7 T 14-10-2018 IPR006171 TOPRIM domain Tharo_3406 2d88b2e48277353921d0f8e5ca711d0a 123 SUPERFAMILY SSF50249 12 122 4.16E-32 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_3406 2d88b2e48277353921d0f8e5ca711d0a 123 PIRSF PIRSF002070 11 122 2.2E-29 T 14-10-2018 Tharo_3406 2d88b2e48277353921d0f8e5ca711d0a 123 Pfam PF00436 Single-strand binding protein family 14 114 7.1E-25 T 14-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 Tharo_3406 2d88b2e48277353921d0f8e5ca711d0a 123 Hamap MF_00984 Single-stranded DNA-binding protein. 13 119 23.899 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 Tharo_3406 2d88b2e48277353921d0f8e5ca711d0a 123 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 12 118 1.1E-29 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 Tharo_3406 2d88b2e48277353921d0f8e5ca711d0a 123 Gene3D G3DSA:2.40.50.140 11 123 8.7E-31 T 14-10-2018 Tharo_0502 663244c2816a6ad9d598f9c6b23ab995 91 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 37 86 2.0E-21 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_0502 663244c2816a6ad9d598f9c6b23ab995 91 TIGRFAM TIGR00165 S18: ribosomal protein bS18 21 88 8.7E-34 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_0502 663244c2816a6ad9d598f9c6b23ab995 91 Gene3D G3DSA:4.10.640.10 4 90 8.9E-26 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_0502 663244c2816a6ad9d598f9c6b23ab995 91 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 18 89 20.226 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_0502 663244c2816a6ad9d598f9c6b23ab995 91 Pfam PF01084 Ribosomal protein S18 33 84 1.7E-23 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_0502 663244c2816a6ad9d598f9c6b23ab995 91 PRINTS PR00974 Ribosomal protein S18 family signature 54 61 1.4E-15 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_0502 663244c2816a6ad9d598f9c6b23ab995 91 PRINTS PR00974 Ribosomal protein S18 family signature 76 86 1.4E-15 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_0502 663244c2816a6ad9d598f9c6b23ab995 91 PRINTS PR00974 Ribosomal protein S18 family signature 44 54 1.4E-15 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_0502 663244c2816a6ad9d598f9c6b23ab995 91 PRINTS PR00974 Ribosomal protein S18 family signature 62 76 1.4E-15 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_0502 663244c2816a6ad9d598f9c6b23ab995 91 SUPERFAMILY SSF46911 16 87 1.19E-26 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_0502 663244c2816a6ad9d598f9c6b23ab995 91 ProSitePatterns PS00057 Ribosomal protein S18 signature. 37 60 - T 14-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1503 86174c1b663d62a997624d089b496644 343 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 206 270 5.0E-26 T 14-10-2018 IPR017703 YgfZ/GcvT conserved site Tharo_1503 86174c1b663d62a997624d089b496644 343 Pfam PF01571 Aminomethyltransferase folate-binding domain 20 221 3.3E-15 T 14-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain Tharo_1503 86174c1b663d62a997624d089b496644 343 Gene3D G3DSA:3.30.1360.120 11 341 9.3E-59 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 Tharo_1503 86174c1b663d62a997624d089b496644 343 SUPERFAMILY SSF103025 20 261 4.71E-59 T 14-10-2018 Tharo_1503 86174c1b663d62a997624d089b496644 343 SUPERFAMILY SSF101790 263 342 2.42E-9 T 14-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal Tharo_1503 86174c1b663d62a997624d089b496644 343 PIRSF PIRSF006487 1 342 3.5E-15 T 14-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 SUPERFAMILY SSF51905 1 361 1.83E-58 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 PIRSF PIRSF000350 1 443 1.2E-91 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 316 1.4E-66 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 38 48 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 Gene3D G3DSA:3.50.50.60 4 320 3.6E-118 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 133 142 7.7E-74 T 14-10-2018 Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 398 413 7.7E-74 T 14-10-2018 Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 7.7E-74 T 14-10-2018 Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 167 192 7.7E-74 T 14-10-2018 Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 420 440 7.7E-74 T 14-10-2018 Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 7.7E-74 T 14-10-2018 Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 296 303 7.7E-74 T 14-10-2018 Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 253 267 7.7E-74 T 14-10-2018 Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 333 354 7.7E-74 T 14-10-2018 Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 337 445 3.4E-36 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 SUPERFAMILY SSF55424 334 446 6.7E-36 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 130 148 2.8E-28 T 14-10-2018 Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.8E-28 T 14-10-2018 Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 167 185 2.8E-28 T 14-10-2018 Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 268 2.8E-28 T 14-10-2018 Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 281 303 2.8E-28 T 14-10-2018 Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 TIGRFAM TIGR01421 gluta_reduc_1: glutathione-disulfide reductase 3 446 4.1E-195 T 14-10-2018 IPR006322 Glutathione reductase, eukaryote/bacterial GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081|Reactome: R-HSA-2408550|Reactome: R-HSA-3299685|Reactome: R-HSA-499943|Reactome: R-HSA-5628897 Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 Gene3D G3DSA:3.50.50.60 142 259 3.6E-118 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1497 c411968401a3d3c2efee51c8d2cb5c0c 447 Gene3D G3DSA:3.30.390.30 336 447 1.1E-48 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Tharo_0188 16a96d7f6f17ad08f8cf7dd1a5deeb43 461 Pfam PF02219 Methylenetetrahydrofolate reductase 172 460 5.5E-32 T 14-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 Tharo_0188 16a96d7f6f17ad08f8cf7dd1a5deeb43 461 Pfam PF12225 Methylene-tetrahydrofolate reductase C terminal 48 122 5.4E-24 T 14-10-2018 IPR022026 Methylene-tetrahydrofolate reductase C-terminal Tharo_0188 16a96d7f6f17ad08f8cf7dd1a5deeb43 461 SUPERFAMILY SSF51730 172 460 4.51E-66 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like Tharo_0188 16a96d7f6f17ad08f8cf7dd1a5deeb43 461 Gene3D G3DSA:3.20.20.220 171 461 1.2E-52 T 14-10-2018 Tharo_3270 9e4fba2ff8b669dc400d6ae57b0db934 301 Pfam PF07804 HipA-like C-terminal domain 147 257 5.4E-23 T 14-10-2018 IPR012893 HipA-like, C-terminal Tharo_3270 9e4fba2ff8b669dc400d6ae57b0db934 301 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 4 102 4.2E-32 T 14-10-2018 IPR017508 HipA, N-terminal subdomain 1 Tharo_3270 9e4fba2ff8b669dc400d6ae57b0db934 301 Pfam PF13657 HipA N-terminal domain 5 102 1.9E-24 T 14-10-2018 IPR017508 HipA, N-terminal subdomain 1 Tharo_2697 b1b399d205729d6722597f47d7a049ef 348 Gene3D G3DSA:3.40.50.720 4 275 2.5E-142 T 14-10-2018 Tharo_2697 b1b399d205729d6722597f47d7a049ef 348 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 263 1.5E-56 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 Tharo_2697 b1b399d205729d6722597f47d7a049ef 348 Gene3D G3DSA:3.90.25.10 195 330 2.5E-142 T 14-10-2018 Tharo_2697 b1b399d205729d6722597f47d7a049ef 348 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 3 336 1.6E-136 T 14-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 Tharo_2697 b1b399d205729d6722597f47d7a049ef 348 SUPERFAMILY SSF51735 2 337 5.91E-95 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1470 da5fc6dc2f777b14065b265273b09d5a 224 Pfam PF04367 Protein of unknown function (DUF502) 78 179 5.5E-27 T 14-10-2018 IPR007462 Protein of unknown function DUF502 Tharo_2543 0acf80289b45f059afad6a4935519201 708 Pfam PF01968 Hydantoinase/oxoprolinase 208 494 7.5E-90 T 14-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 Tharo_2543 0acf80289b45f059afad6a4935519201 708 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 4 187 8.9E-48 T 14-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 Tharo_0961 45593c213c401d12e88ab2039f1ef4f0 448 Gene3D G3DSA:1.10.287.470 100 167 1.3E-6 T 14-10-2018 Tharo_0961 45593c213c401d12e88ab2039f1ef4f0 448 Pfam PF13437 HlyD family secretion protein 298 401 1.5E-11 T 14-10-2018 Tharo_0961 45593c213c401d12e88ab2039f1ef4f0 448 Pfam PF13533 Biotin-lipoyl like 73 100 2.6E-5 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain Tharo_0961 45593c213c401d12e88ab2039f1ef4f0 448 Gene3D G3DSA:2.40.50.100 74 99 1.3E-6 T 14-10-2018 Tharo_0961 45593c213c401d12e88ab2039f1ef4f0 448 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 35 58 3.8E-53 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_0961 45593c213c401d12e88ab2039f1ef4f0 448 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 343 367 3.8E-53 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_0961 45593c213c401d12e88ab2039f1ef4f0 448 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 310 331 3.8E-53 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_0961 45593c213c401d12e88ab2039f1ef4f0 448 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 412 427 3.8E-53 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_0961 45593c213c401d12e88ab2039f1ef4f0 448 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 427 447 3.8E-53 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_0961 45593c213c401d12e88ab2039f1ef4f0 448 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 77 97 3.8E-53 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_0961 45593c213c401d12e88ab2039f1ef4f0 448 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 367 390 3.8E-53 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_0961 45593c213c401d12e88ab2039f1ef4f0 448 Gene3D G3DSA:2.40.30.170 335 425 7.3E-12 T 14-10-2018 Tharo_0961 45593c213c401d12e88ab2039f1ef4f0 448 Gene3D G3DSA:1.10.287.470 224 297 7.3E-12 T 14-10-2018 Tharo_0961 45593c213c401d12e88ab2039f1ef4f0 448 Gene3D G3DSA:2.40.50.100 298 334 7.3E-12 T 14-10-2018 Tharo_0961 45593c213c401d12e88ab2039f1ef4f0 448 SUPERFAMILY SSF111369 73 124 1.19E-5 T 14-10-2018 Tharo_0961 45593c213c401d12e88ab2039f1ef4f0 448 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 25 448 2.6E-112 T 14-10-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 Tharo_0580 21b7f1221fa801b82a9673bb993723cf 75 SUPERFAMILY SSF46955 17 69 5.86E-10 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily Tharo_0580 21b7f1221fa801b82a9673bb993723cf 75 Pfam PF12728 Helix-turn-helix domain 22 67 1.0E-11 T 14-10-2018 Tharo_3390 41e37b2e328b72c93ec01e7b58e1a08d 706 SUPERFAMILY SSF55874 556 700 1.31E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_3390 41e37b2e328b72c93ec01e7b58e1a08d 706 Gene3D G3DSA:3.30.565.10 556 705 1.4E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_3390 41e37b2e328b72c93ec01e7b58e1a08d 706 SUPERFAMILY SSF55785 357 473 9.33E-9 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_3390 41e37b2e328b72c93ec01e7b58e1a08d 706 SMART SM00387 593 701 3.0E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_3390 41e37b2e328b72c93ec01e7b58e1a08d 706 PIRSF PIRSF037532 1 705 1.9E-231 T 14-10-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator Tharo_3390 41e37b2e328b72c93ec01e7b58e1a08d 706 Pfam PF00512 His Kinase A (phospho-acceptor) domain 484 553 1.5E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_3390 41e37b2e328b72c93ec01e7b58e1a08d 706 SUPERFAMILY SSF158472 299 348 9.81E-9 T 14-10-2018 Tharo_3390 41e37b2e328b72c93ec01e7b58e1a08d 706 SMART SM00304 299 351 1.3E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_3390 41e37b2e328b72c93ec01e7b58e1a08d 706 SUPERFAMILY SSF47384 478 556 7.06E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_3390 41e37b2e328b72c93ec01e7b58e1a08d 706 Pfam PF00672 HAMP domain 299 347 5.3E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_3390 41e37b2e328b72c93ec01e7b58e1a08d 706 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 593 700 9.8E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_3390 41e37b2e328b72c93ec01e7b58e1a08d 706 Gene3D G3DSA:1.20.1480.50 267 357 2.0E-10 T 14-10-2018 Tharo_3390 41e37b2e328b72c93ec01e7b58e1a08d 706 SMART SM00388 483 555 3.0E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_3390 41e37b2e328b72c93ec01e7b58e1a08d 706 PRINTS PR00344 Bacterial sensor protein C-terminal signature 685 698 3.2E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3390 41e37b2e328b72c93ec01e7b58e1a08d 706 PRINTS PR00344 Bacterial sensor protein C-terminal signature 661 679 3.2E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3390 41e37b2e328b72c93ec01e7b58e1a08d 706 PRINTS PR00344 Bacterial sensor protein C-terminal signature 632 646 3.2E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3390 41e37b2e328b72c93ec01e7b58e1a08d 706 PRINTS PR00344 Bacterial sensor protein C-terminal signature 650 660 3.2E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3390 41e37b2e328b72c93ec01e7b58e1a08d 706 Gene3D G3DSA:1.10.287.130 473 552 8.2E-13 T 14-10-2018 Tharo_3306 258bdefe1e741028d841dd887875f4da 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 6.8E-25 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_3306 258bdefe1e741028d841dd887875f4da 299 SUPERFAMILY SSF46785 1 84 4.5E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_3306 258bdefe1e741028d841dd887875f4da 299 SUPERFAMILY SSF53850 91 296 2.65E-38 T 14-10-2018 Tharo_3306 258bdefe1e741028d841dd887875f4da 299 Gene3D G3DSA:3.40.190.10 88 289 1.6E-61 T 14-10-2018 Tharo_3306 258bdefe1e741028d841dd887875f4da 299 Gene3D G3DSA:3.40.190.10 165 270 1.6E-61 T 14-10-2018 Tharo_3306 258bdefe1e741028d841dd887875f4da 299 Pfam PF03466 LysR substrate binding domain 88 292 8.3E-40 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_3306 258bdefe1e741028d841dd887875f4da 299 Gene3D G3DSA:1.10.10.10 1 85 5.6E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_3306 258bdefe1e741028d841dd887875f4da 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.4E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_3306 258bdefe1e741028d841dd887875f4da 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.4E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_3306 258bdefe1e741028d841dd887875f4da 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.4E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1405 44ae7648ce027c3fb71d8423fa3006a1 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 1.9E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_1405 44ae7648ce027c3fb71d8423fa3006a1 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 1.9E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_1405 44ae7648ce027c3fb71d8423fa3006a1 248 Gene3D G3DSA:1.10.10.10 3 71 6.7E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1405 44ae7648ce027c3fb71d8423fa3006a1 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 70 1.4E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_1405 44ae7648ce027c3fb71d8423fa3006a1 248 TIGRFAM TIGR02018 his_ut_repres: histidine utilization repressor 6 233 2.7E-85 T 14-10-2018 IPR010248 Histidine utilization repressor GO:0003677|GO:0006547|GO:0045892 Tharo_1405 44ae7648ce027c3fb71d8423fa3006a1 248 SMART SM00866 91 228 8.9E-36 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Tharo_1405 44ae7648ce027c3fb71d8423fa3006a1 248 SUPERFAMILY SSF64288 58 232 2.04E-43 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily Tharo_1405 44ae7648ce027c3fb71d8423fa3006a1 248 SUPERFAMILY SSF46785 3 74 4.77E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1405 44ae7648ce027c3fb71d8423fa3006a1 248 Pfam PF07702 UTRA domain 92 228 5.8E-34 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Tharo_1405 44ae7648ce027c3fb71d8423fa3006a1 248 SMART SM00345 11 70 1.5E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_1405 44ae7648ce027c3fb71d8423fa3006a1 248 Gene3D G3DSA:3.40.1410.10 90 224 9.4E-35 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily Tharo_3004 a109d3e3e748f9846fe36c69038b38b6 508 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 33 54 4.0E-5 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal Tharo_3004 a109d3e3e748f9846fe36c69038b38b6 508 Pfam PF01593 Flavin containing amine oxidoreductase 80 495 1.4E-47 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 Tharo_3004 a109d3e3e748f9846fe36c69038b38b6 508 Gene3D G3DSA:3.50.50.60 71 495 1.6E-121 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_3004 a109d3e3e748f9846fe36c69038b38b6 508 SUPERFAMILY SSF51905 70 496 8.63E-60 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_3004 a109d3e3e748f9846fe36c69038b38b6 508 Gene3D G3DSA:3.90.660.10 148 438 1.6E-121 T 14-10-2018 Tharo_3004 a109d3e3e748f9846fe36c69038b38b6 508 PRINTS PR00757 Flavin-containing amine oxidase signature 72 91 3.3E-9 T 14-10-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 Tharo_3004 a109d3e3e748f9846fe36c69038b38b6 508 PRINTS PR00757 Flavin-containing amine oxidase signature 477 494 3.3E-9 T 14-10-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 Tharo_3004 a109d3e3e748f9846fe36c69038b38b6 508 PRINTS PR00757 Flavin-containing amine oxidase signature 446 468 3.3E-9 T 14-10-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 Tharo_2080 31f97b9cfd3b1f231e57932b9b4ab907 314 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 25 308 2.9E-61 T 14-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 Tharo_2080 31f97b9cfd3b1f231e57932b9b4ab907 314 Gene3D G3DSA:3.40.50.150 114 292 4.9E-47 T 14-10-2018 Tharo_2080 31f97b9cfd3b1f231e57932b9b4ab907 314 Pfam PF05175 Methyltransferase small domain 145 230 3.9E-18 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 Tharo_2080 31f97b9cfd3b1f231e57932b9b4ab907 314 SUPERFAMILY SSF53335 26 294 1.02E-50 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_2080 31f97b9cfd3b1f231e57932b9b4ab907 314 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 23 306 1.1E-117 T 14-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 Tharo_2080 31f97b9cfd3b1f231e57932b9b4ab907 314 PIRSF PIRSF037167 9 314 2.2E-121 T 14-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 Tharo_2080 31f97b9cfd3b1f231e57932b9b4ab907 314 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 216 222 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Tharo_2080 31f97b9cfd3b1f231e57932b9b4ab907 314 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 16 312 48.484 T 14-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 Tharo_3407 fb66cb7be7c7b7e05f1642d156bea5fe 106 Gene3D G3DSA:1.10.260.40 1 54 1.0E-9 T 14-10-2018 Tharo_3407 fb66cb7be7c7b7e05f1642d156bea5fe 106 SUPERFAMILY SSF47413 1 51 6.48E-10 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_3407 fb66cb7be7c7b7e05f1642d156bea5fe 106 Gene3D G3DSA:1.10.10.2690 55 102 2.1E-7 T 14-10-2018 Tharo_3407 fb66cb7be7c7b7e05f1642d156bea5fe 106 Pfam PF01381 Helix-turn-helix 1 45 7.3E-9 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_0781 58c198b9771493df2cda017ef6efcadf 399 Gene3D G3DSA:1.10.3290.10 51 303 3.7E-43 T 14-10-2018 IPR036597 Fido-like domain superfamily Tharo_0781 58c198b9771493df2cda017ef6efcadf 399 SUPERFAMILY SSF46785 318 381 3.42E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0781 58c198b9771493df2cda017ef6efcadf 399 SUPERFAMILY SSF140931 110 310 1.31E-36 T 14-10-2018 IPR036597 Fido-like domain superfamily Tharo_0781 58c198b9771493df2cda017ef6efcadf 399 Pfam PF13784 Fic/DOC family N-terminal 46 125 7.7E-18 T 14-10-2018 IPR025758 Fic/DOC N-terminal Tharo_0781 58c198b9771493df2cda017ef6efcadf 399 PIRSF PIRSF038925 36 388 2.9E-79 T 14-10-2018 IPR026287 Adenosine monophosphate-protein transferase Tharo_0781 58c198b9771493df2cda017ef6efcadf 399 Pfam PF02661 Fic/DOC family 139 244 2.5E-18 T 14-10-2018 IPR003812 Fido domain Tharo_1655 12cc0c2bb912c89f91299956bd01c124 86 SUPERFAMILY SSF116842 7 72 6.8E-20 T 14-10-2018 Tharo_1655 12cc0c2bb912c89f91299956bd01c124 86 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 11 71 15.424 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Tharo_1655 12cc0c2bb912c89f91299956bd01c124 86 Pfam PF02609 Exonuclease VII small subunit 12 62 2.7E-19 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Tharo_1655 12cc0c2bb912c89f91299956bd01c124 86 Gene3D G3DSA:1.10.287.1040 5 80 1.1E-25 T 14-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 Tharo_1655 12cc0c2bb912c89f91299956bd01c124 86 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 11 64 5.1E-22 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Tharo_1655 12cc0c2bb912c89f91299956bd01c124 86 PIRSF PIRSF006488 1 83 4.2E-23 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Tharo_1655 12cc0c2bb912c89f91299956bd01c124 86 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 11 51 2.0E-8 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Tharo_2146 dfe324169f28d5e3e7f9797327ec8656 208 Gene3D G3DSA:3.30.420.10 3 198 5.8E-33 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_2146 dfe324169f28d5e3e7f9797327ec8656 208 Pfam PF00929 Exonuclease 6 188 6.5E-12 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Tharo_2146 dfe324169f28d5e3e7f9797327ec8656 208 SUPERFAMILY SSF53098 1 197 2.74E-30 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_2146 dfe324169f28d5e3e7f9797327ec8656 208 SMART SM00479 3 200 1.9E-6 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Tharo_0216 47f1d54a190402d95bd2494741792433 754 TIGRFAM TIGR03549 TIGR03549: YcaO domain protein 2 728 0.0 T 14-10-2018 IPR019938 YcaO domain protein Tharo_0216 47f1d54a190402d95bd2494741792433 754 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 159 551 5.1E-97 T 14-10-2018 IPR003776 YcaO-like domain Tharo_0216 47f1d54a190402d95bd2494741792433 754 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 205 540 9.0E-70 T 14-10-2018 IPR003776 YcaO-like domain Tharo_0216 47f1d54a190402d95bd2494741792433 754 SUPERFAMILY SSF82784 1 127 1.96E-20 T 14-10-2018 IPR036102 OsmC/Ohr superfamily Tharo_0216 47f1d54a190402d95bd2494741792433 754 Pfam PF02566 OsmC-like protein 32 126 3.7E-10 T 14-10-2018 IPR003718 OsmC/Ohr family Tharo_0216 47f1d54a190402d95bd2494741792433 754 Gene3D G3DSA:3.30.300.20 3 128 1.2E-15 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta Tharo_0578 1079cbcda2e1f5b0acf8ce72925cba71 86 Gene3D G3DSA:3.30.2020.10 3 81 7.8E-13 T 14-10-2018 IPR036782 NE0471-like, N-terminal Tharo_0578 1079cbcda2e1f5b0acf8ce72925cba71 86 Pfam PF10387 Protein of unknown function (DUF2442) 6 75 1.0E-15 T 14-10-2018 IPR018841 Protein of unknown function DUF2442 Tharo_0578 1079cbcda2e1f5b0acf8ce72925cba71 86 SUPERFAMILY SSF143880 2 81 7.32E-22 T 14-10-2018 IPR036782 NE0471-like, N-terminal Tharo_2349 ad060894941cd384c60b6efc029a9b1f 281 Pfam PF00795 Carbon-nitrogen hydrolase 18 269 7.6E-52 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 Tharo_2349 ad060894941cd384c60b6efc029a9b1f 281 SUPERFAMILY SSF56317 14 278 1.57E-78 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Tharo_2349 ad060894941cd384c60b6efc029a9b1f 281 Gene3D G3DSA:3.60.110.10 11 280 4.5E-87 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Tharo_2349 ad060894941cd384c60b6efc029a9b1f 281 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 165 185 - T 14-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site Tharo_1394 f448beb2fc1ea9d779159b5033960fb1 549 SMART SM00671 51 86 4.1E-9 T 14-10-2018 IPR006597 Sel1-like repeat Tharo_1394 f448beb2fc1ea9d779159b5033960fb1 549 Gene3D G3DSA:1.25.40.10 385 540 1.4E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_1394 f448beb2fc1ea9d779159b5033960fb1 549 Gene3D G3DSA:1.25.40.10 8 181 1.9E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_1394 f448beb2fc1ea9d779159b5033960fb1 549 SUPERFAMILY SSF81901 12 154 8.37E-15 T 14-10-2018 Tharo_1394 f448beb2fc1ea9d779159b5033960fb1 549 Pfam PF08238 Sel1 repeat 51 85 3.0E-7 T 14-10-2018 IPR006597 Sel1-like repeat Tharo_1394 f448beb2fc1ea9d779159b5033960fb1 549 SUPERFAMILY SSF48452 389 482 5.26E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_1105 40d4b891f969996931f00666ce514f8a 331 SUPERFAMILY SSF51430 1 312 6.02E-92 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Tharo_1105 40d4b891f969996931f00666ce514f8a 331 PRINTS PR00069 Aldo-keto reductase signature 41 65 1.3E-5 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Tharo_1105 40d4b891f969996931f00666ce514f8a 331 PRINTS PR00069 Aldo-keto reductase signature 136 153 1.3E-5 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Tharo_1105 40d4b891f969996931f00666ce514f8a 331 PRINTS PR00069 Aldo-keto reductase signature 105 123 1.3E-5 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Tharo_1105 40d4b891f969996931f00666ce514f8a 331 Pfam PF00248 Aldo/keto reductase family 14 308 1.3E-71 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain Tharo_1105 40d4b891f969996931f00666ce514f8a 331 Gene3D G3DSA:3.20.20.100 1 329 6.3E-104 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Tharo_2311 fe2d3e886ceb256711c8cf3467c155b6 745 Pfam PF03971 Monomeric isocitrate dehydrogenase 7 740 0.0 T 14-10-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 Tharo_2311 fe2d3e886ceb256711c8cf3467c155b6 745 SUPERFAMILY SSF53659 5 742 0.0 T 14-10-2018 Tharo_2311 fe2d3e886ceb256711c8cf3467c155b6 745 Gene3D G3DSA:3.40.718.10 409 666 1.9E-6 T 14-10-2018 Tharo_2311 fe2d3e886ceb256711c8cf3467c155b6 745 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 1 742 0.0 T 14-10-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 Tharo_2311 fe2d3e886ceb256711c8cf3467c155b6 745 PIRSF PIRSF009407 1 744 0.0 T 14-10-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 Tharo_2168 885fe8d0c67b6036ff6cd9f2c3ab79c4 462 Gene3D G3DSA:1.10.530.10 121 267 6.2E-30 T 14-10-2018 Tharo_2168 885fe8d0c67b6036ff6cd9f2c3ab79c4 462 Gene3D G3DSA:3.10.350.10 294 336 4.0E-7 T 14-10-2018 IPR036779 LysM domain superfamily Tharo_2168 885fe8d0c67b6036ff6cd9f2c3ab79c4 462 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 143 171 - T 14-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 Tharo_2168 885fe8d0c67b6036ff6cd9f2c3ab79c4 462 SUPERFAMILY SSF53955 122 264 4.92E-39 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily Tharo_2168 885fe8d0c67b6036ff6cd9f2c3ab79c4 462 Pfam PF01464 Transglycosylase SLT domain 132 233 1.7E-23 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 Tharo_2168 885fe8d0c67b6036ff6cd9f2c3ab79c4 462 Gene3D G3DSA:3.10.350.10 337 395 4.0E-7 T 14-10-2018 IPR036779 LysM domain superfamily Tharo_1402 b7403fabcabcd7dec5fa9b6e58cc33d9 320 Pfam PF03462 PCRF domain 1 175 1.4E-53 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 Tharo_1402 b7403fabcabcd7dec5fa9b6e58cc33d9 320 Pfam PF00472 RF-1 domain 184 292 9.8E-43 T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Tharo_1402 b7403fabcabcd7dec5fa9b6e58cc33d9 320 Gene3D G3DSA:3.30.160.20 181 276 9.1E-98 T 14-10-2018 Tharo_1402 b7403fabcabcd7dec5fa9b6e58cc33d9 320 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 1 318 2.8E-152 T 14-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 Tharo_1402 b7403fabcabcd7dec5fa9b6e58cc33d9 320 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 200 216 - T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Tharo_1402 b7403fabcabcd7dec5fa9b6e58cc33d9 320 Gene3D G3DSA:3.30.70.1660 85 312 9.1E-98 T 14-10-2018 Tharo_1402 b7403fabcabcd7dec5fa9b6e58cc33d9 320 Gene3D G3DSA:1.20.58.410 1 71 1.8E-17 T 14-10-2018 Tharo_1402 b7403fabcabcd7dec5fa9b6e58cc33d9 320 SMART SM00937 40 150 8.4E-54 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 Tharo_1402 b7403fabcabcd7dec5fa9b6e58cc33d9 320 SUPERFAMILY SSF75620 1 317 1.01E-129 T 14-10-2018 Tharo_1402 b7403fabcabcd7dec5fa9b6e58cc33d9 320 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 320 35.084 T 14-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 Tharo_0441 a1a8be8314794147ba4e90c42b86e9cd 481 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 242 401 5.3E-81 T 14-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Tharo_0441 a1a8be8314794147ba4e90c42b86e9cd 481 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 12 473 47.926 T 14-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 Tharo_0441 a1a8be8314794147ba4e90c42b86e9cd 481 SUPERFAMILY SSF52283 14 481 1.47E-108 T 14-10-2018 Tharo_0441 a1a8be8314794147ba4e90c42b86e9cd 481 SMART SM00997 242 401 3.1E-113 T 14-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Tharo_0441 a1a8be8314794147ba4e90c42b86e9cd 481 SMART SM00996 16 480 0.0 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Tharo_0441 a1a8be8314794147ba4e90c42b86e9cd 481 Gene3D G3DSA:3.40.50.1480 17 481 5.6E-233 T 14-10-2018 Tharo_0441 a1a8be8314794147ba4e90c42b86e9cd 481 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 16 480 2.0E-140 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Tharo_0441 a1a8be8314794147ba4e90c42b86e9cd 481 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 88 102 - T 14-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Tharo_0441 a1a8be8314794147ba4e90c42b86e9cd 481 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 264 280 - T 14-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Tharo_0441 a1a8be8314794147ba4e90c42b86e9cd 481 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 17 473 1.0E-180 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Tharo_0441 a1a8be8314794147ba4e90c42b86e9cd 481 PIRSF PIRSF001109 4 481 1.6E-184 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Tharo_0441 a1a8be8314794147ba4e90c42b86e9cd 481 SUPERFAMILY SSF51735 242 401 2.56E-79 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_0441 a1a8be8314794147ba4e90c42b86e9cd 481 Gene3D G3DSA:3.40.50.720 244 401 5.6E-233 T 14-10-2018 Tharo_3061 b9ccb36548ca2cf20f7a16c74c8923e4 145 SUPERFAMILY SSF52402 2 145 5.69E-32 T 14-10-2018 Tharo_3061 b9ccb36548ca2cf20f7a16c74c8923e4 145 Pfam PF00582 Universal stress protein family 2 145 1.3E-27 T 14-10-2018 IPR006016 UspA Tharo_3061 b9ccb36548ca2cf20f7a16c74c8923e4 145 PRINTS PR01438 Universal stress protein signature 2 20 1.8E-13 T 14-10-2018 IPR006015 Universal stress protein A Tharo_3061 b9ccb36548ca2cf20f7a16c74c8923e4 145 PRINTS PR01438 Universal stress protein signature 105 117 1.8E-13 T 14-10-2018 IPR006015 Universal stress protein A Tharo_3061 b9ccb36548ca2cf20f7a16c74c8923e4 145 PRINTS PR01438 Universal stress protein signature 123 145 1.8E-13 T 14-10-2018 IPR006015 Universal stress protein A Tharo_3061 b9ccb36548ca2cf20f7a16c74c8923e4 145 Gene3D G3DSA:3.40.50.620 1 145 2.1E-32 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_1157 537d27c9595f1a97bc923e355e87c301 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 6.3E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1157 537d27c9595f1a97bc923e355e87c301 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 6.3E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1157 537d27c9595f1a97bc923e355e87c301 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 6.3E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1157 537d27c9595f1a97bc923e355e87c301 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 6.3E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1157 537d27c9595f1a97bc923e355e87c301 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 6.3E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1157 537d27c9595f1a97bc923e355e87c301 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 6.3E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1157 537d27c9595f1a97bc923e355e87c301 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.8E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1157 537d27c9595f1a97bc923e355e87c301 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.8E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1157 537d27c9595f1a97bc923e355e87c301 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.8E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1157 537d27c9595f1a97bc923e355e87c301 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 244 9.1E-63 T 14-10-2018 Tharo_1157 537d27c9595f1a97bc923e355e87c301 246 Gene3D G3DSA:3.40.50.720 1 246 2.2E-81 T 14-10-2018 Tharo_1157 537d27c9595f1a97bc923e355e87c301 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Tharo_1157 537d27c9595f1a97bc923e355e87c301 246 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 4 245 2.0E-118 T 14-10-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216|MetaCyc: PWY-7948 Tharo_1157 537d27c9595f1a97bc923e355e87c301 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 189 3.7E-4 T 14-10-2018 Tharo_1157 537d27c9595f1a97bc923e355e87c301 246 SUPERFAMILY SSF51735 3 245 3.5E-81 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_2151 55797d66019a96c08d100630278cd6e8 520 Pfam PF00145 C-5 cytosine-specific DNA methylase 16 200 4.4E-20 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 Tharo_2151 55797d66019a96c08d100630278cd6e8 520 Pfam PF00145 C-5 cytosine-specific DNA methylase 433 507 3.8E-8 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 Tharo_2151 55797d66019a96c08d100630278cd6e8 520 SUPERFAMILY SSF53335 16 506 1.12E-72 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_2151 55797d66019a96c08d100630278cd6e8 520 Gene3D G3DSA:3.40.50.150 468 503 1.1E-7 T 14-10-2018 Tharo_2151 55797d66019a96c08d100630278cd6e8 520 Gene3D G3DSA:3.90.120.10 441 467 1.1E-7 T 14-10-2018 Tharo_2151 55797d66019a96c08d100630278cd6e8 520 Gene3D G3DSA:3.40.50.150 15 203 3.7E-44 T 14-10-2018 Tharo_2151 55797d66019a96c08d100630278cd6e8 520 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 180 193 4.7E-10 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 Tharo_2151 55797d66019a96c08d100630278cd6e8 520 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 15 31 4.7E-10 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 Tharo_2151 55797d66019a96c08d100630278cd6e8 520 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 118 132 4.7E-10 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 Tharo_2025 de0d06ffc5e03da1482f3eb0e824f623 306 Gene3D G3DSA:3.90.25.10 173 299 6.2E-109 T 14-10-2018 Tharo_2025 de0d06ffc5e03da1482f3eb0e824f623 306 SUPERFAMILY SSF51735 1 304 1.29E-101 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_2025 de0d06ffc5e03da1482f3eb0e824f623 306 Gene3D G3DSA:3.40.50.720 3 291 6.2E-109 T 14-10-2018 Tharo_2025 de0d06ffc5e03da1482f3eb0e824f623 306 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 303 4.5E-100 T 14-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 Tharo_2025 de0d06ffc5e03da1482f3eb0e824f623 306 Pfam PF04321 RmlD substrate binding domain 1 304 3.2E-106 T 14-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 Tharo_1029 bf1fd0307f7538479a797472076ca230 197 Pfam PF00355 Rieske [2Fe-2S] domain 54 180 1.1E-10 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Tharo_1029 bf1fd0307f7538479a797472076ca230 197 SUPERFAMILY SSF50022 30 191 2.02E-41 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Tharo_1029 bf1fd0307f7538479a797472076ca230 197 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 1 40 7.3E-9 T 14-10-2018 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 Tharo_1029 bf1fd0307f7538479a797472076ca230 197 PRINTS PR00162 Rieske 2Fe-2S subunit signature 119 130 2.9E-5 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 Tharo_1029 bf1fd0307f7538479a797472076ca230 197 PRINTS PR00162 Rieske 2Fe-2S subunit signature 151 163 2.9E-5 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 Tharo_1029 bf1fd0307f7538479a797472076ca230 197 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 10 192 1.9E-65 T 14-10-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 Tharo_1029 bf1fd0307f7538479a797472076ca230 197 Gene3D G3DSA:2.102.10.10 43 192 2.3E-48 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Tharo_2716 ace7305f8340bac3192bf35802b33709 64 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 14-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2716 ace7305f8340bac3192bf35802b33709 64 Gene3D G3DSA:1.10.287.310 1 62 2.3E-28 T 14-10-2018 Tharo_2716 ace7305f8340bac3192bf35802b33709 64 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.426 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2716 ace7305f8340bac3192bf35802b33709 64 SUPERFAMILY SSF46561 1 61 3.79E-22 T 14-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2716 ace7305f8340bac3192bf35802b33709 64 Pfam PF00831 Ribosomal L29 protein 5 60 3.7E-24 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2716 ace7305f8340bac3192bf35802b33709 64 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 8.8E-23 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_0589 34c31f46f63ae507b905353e08f3f6d2 1104 Pfam PF13086 AAA domain 416 815 2.5E-31 T 14-10-2018 Tharo_0589 34c31f46f63ae507b905353e08f3f6d2 1104 SMART SM00382 428 829 0.0067 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0589 34c31f46f63ae507b905353e08f3f6d2 1104 SUPERFAMILY SSF52540 415 1079 3.3E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0589 34c31f46f63ae507b905353e08f3f6d2 1104 Pfam PF13087 AAA domain 837 1074 2.3E-37 T 14-10-2018 Tharo_0589 34c31f46f63ae507b905353e08f3f6d2 1104 Gene3D G3DSA:3.40.50.300 868 1102 1.7E-37 T 14-10-2018 Tharo_0665 18d9596db94bfaef61e4191083b1bb10 298 SMART SM01400 4 118 6.0E-29 T 14-10-2018 Tharo_0665 18d9596db94bfaef61e4191083b1bb10 298 SUPERFAMILY SSF53271 9 159 1.06E-35 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Tharo_0665 18d9596db94bfaef61e4191083b1bb10 298 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 7 290 4.5E-55 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Tharo_0665 18d9596db94bfaef61e4191083b1bb10 298 Gene3D G3DSA:3.40.50.2020 147 272 2.0E-70 T 14-10-2018 Tharo_0665 18d9596db94bfaef61e4191083b1bb10 298 SUPERFAMILY SSF53271 159 281 1.31E-24 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Tharo_0665 18d9596db94bfaef61e4191083b1bb10 298 Pfam PF00156 Phosphoribosyl transferase domain 150 248 1.7E-14 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Tharo_0665 18d9596db94bfaef61e4191083b1bb10 298 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 7 115 2.6E-16 T 14-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Tharo_0665 18d9596db94bfaef61e4191083b1bb10 298 Gene3D G3DSA:3.40.50.2020 14 146 2.0E-70 T 14-10-2018 Tharo_3181 a600f4fa8512290b89e2ef2b1e03e0ae 415 Gene3D G3DSA:2.40.50.100 91 235 2.2E-110 T 14-10-2018 Tharo_3181 a600f4fa8512290b89e2ef2b1e03e0ae 415 Gene3D G3DSA:2.40.420.20 332 401 2.2E-110 T 14-10-2018 Tharo_3181 a600f4fa8512290b89e2ef2b1e03e0ae 415 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 67 403 2.4E-87 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Tharo_3181 a600f4fa8512290b89e2ef2b1e03e0ae 415 Gene3D G3DSA:1.10.287.470 126 199 2.2E-110 T 14-10-2018 Tharo_3181 a600f4fa8512290b89e2ef2b1e03e0ae 415 SUPERFAMILY SSF111369 81 328 3.79E-84 T 14-10-2018 Tharo_3181 a600f4fa8512290b89e2ef2b1e03e0ae 415 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 92 321 2.4E-12 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Tharo_3181 a600f4fa8512290b89e2ef2b1e03e0ae 415 Pfam PF00529 HlyD membrane-fusion protein of T1SS 75 388 2.0E-7 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Tharo_3181 a600f4fa8512290b89e2ef2b1e03e0ae 415 Gene3D G3DSA:2.40.30.170 79 331 2.2E-110 T 14-10-2018 Tharo_2225 fcf3e6bde66a139a12763634c86e5ad2 184 Pfam PF03449 Transcription elongation factor, N-terminal 30 100 1.2E-23 T 14-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 Tharo_2225 fcf3e6bde66a139a12763634c86e5ad2 184 SUPERFAMILY SSF54534 111 183 4.05E-21 T 14-10-2018 Tharo_2225 fcf3e6bde66a139a12763634c86e5ad2 184 Gene3D G3DSA:1.10.287.180 28 102 1.7E-26 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 Tharo_2225 fcf3e6bde66a139a12763634c86e5ad2 184 SUPERFAMILY SSF46557 29 103 1.96E-25 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 Tharo_2225 fcf3e6bde66a139a12763634c86e5ad2 184 Hamap MF_00105 Transcription elongation factor GreA [greA]. 28 182 27.222 T 14-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 Tharo_2225 fcf3e6bde66a139a12763634c86e5ad2 184 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 110 183 7.4E-26 T 14-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 Tharo_2225 fcf3e6bde66a139a12763634c86e5ad2 184 PIRSF PIRSF006092 26 184 6.8E-44 T 14-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 Tharo_2225 fcf3e6bde66a139a12763634c86e5ad2 184 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 43 74 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 Tharo_2225 fcf3e6bde66a139a12763634c86e5ad2 184 Hamap MF_00930 Transcription elongation factor GreB [greB]. 27 184 50.054 T 14-10-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 Tharo_2225 fcf3e6bde66a139a12763634c86e5ad2 184 Gene3D G3DSA:3.10.50.30 104 184 1.8E-26 T 14-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 Tharo_2225 fcf3e6bde66a139a12763634c86e5ad2 184 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 147 163 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 Tharo_2225 fcf3e6bde66a139a12763634c86e5ad2 184 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 29 184 8.9E-61 T 14-10-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 Tharo_1968 ca993c266d49995a819815328144f9d2 598 Gene3D G3DSA:1.10.540.10 43 159 1.6E-101 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Tharo_1968 ca993c266d49995a819815328144f9d2 598 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 39 157 7.2E-15 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Tharo_1968 ca993c266d49995a819815328144f9d2 598 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 284 450 1.4E-24 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Tharo_1968 ca993c266d49995a819815328144f9d2 598 SUPERFAMILY SSF56645 38 272 8.77E-63 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Tharo_1968 ca993c266d49995a819815328144f9d2 598 Gene3D G3DSA:2.40.110.10 160 283 1.6E-101 T 14-10-2018 Tharo_1968 ca993c266d49995a819815328144f9d2 598 Gene3D G3DSA:1.20.140.10 284 448 1.6E-101 T 14-10-2018 Tharo_1968 ca993c266d49995a819815328144f9d2 598 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 484 594 9.9E-28 T 14-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain Tharo_1968 ca993c266d49995a819815328144f9d2 598 SUPERFAMILY SSF47203 282 458 3.38E-43 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Tharo_1968 ca993c266d49995a819815328144f9d2 598 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 271 1.3E-15 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Tharo_1968 ca993c266d49995a819815328144f9d2 598 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 4 34 1.2E-10 T 14-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria Tharo_0708 81c550742d992d2a4410379d0525ba40 182 Pfam PF11072 Protein of unknown function (DUF2859) 34 180 4.7E-53 T 14-10-2018 IPR021300 Integrating conjugative element protein, PFL4695 Tharo_0708 81c550742d992d2a4410379d0525ba40 182 TIGRFAM TIGR03765 ICE_PFL_4695: integrating conjugative element protein, PFL_4695 family 78 182 6.0E-42 T 14-10-2018 IPR021300 Integrating conjugative element protein, PFL4695 Tharo_0866 f6c7efb2c475c76c1ee1170c075a9fd2 201 Gene3D G3DSA:3.40.920.10 3 197 3.0E-42 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Tharo_0866 f6c7efb2c475c76c1ee1170c075a9fd2 201 SUPERFAMILY SSF53323 4 194 4.18E-47 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Tharo_0866 f6c7efb2c475c76c1ee1170c075a9fd2 201 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 191 3.0E-42 T 14-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 Tharo_0191 435b4244c91aa39dc298229f438c4c9a 257 Pfam PF01996 F420-0:Gamma-glutamyl ligase 15 234 3.9E-64 T 14-10-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 Tharo_0191 435b4244c91aa39dc298229f438c4c9a 257 SUPERFAMILY SSF144010 8 257 3.53E-77 T 14-10-2018 Tharo_0191 435b4244c91aa39dc298229f438c4c9a 257 Gene3D G3DSA:3.30.1330.100 11 243 3.0E-94 T 14-10-2018 Tharo_0191 435b4244c91aa39dc298229f438c4c9a 257 Gene3D G3DSA:3.90.1660.10 59 257 3.0E-94 T 14-10-2018 Tharo_0191 435b4244c91aa39dc298229f438c4c9a 257 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 7 257 5.3E-86 T 14-10-2018 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 Tharo_1225 d82e9b0d9ea4f82b38ba5607c1fc906c 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 29.786 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1225 d82e9b0d9ea4f82b38ba5607c1fc906c 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.4E-40 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1225 d82e9b0d9ea4f82b38ba5607c1fc906c 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.4E-40 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1225 d82e9b0d9ea4f82b38ba5607c1fc906c 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.4E-40 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1225 d82e9b0d9ea4f82b38ba5607c1fc906c 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1225 d82e9b0d9ea4f82b38ba5607c1fc906c 119 Pfam PF00453 Ribosomal protein L20 3 109 8.6E-49 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1225 d82e9b0d9ea4f82b38ba5607c1fc906c 119 Gene3D G3DSA:1.10.720.90 2 55 1.5E-25 T 14-10-2018 Tharo_1225 d82e9b0d9ea4f82b38ba5607c1fc906c 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 8.3E-50 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1225 d82e9b0d9ea4f82b38ba5607c1fc906c 119 SUPERFAMILY SSF74731 2 115 8.5E-49 T 14-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1225 d82e9b0d9ea4f82b38ba5607c1fc906c 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 71 5.0E-14 T 14-10-2018 Tharo_1225 d82e9b0d9ea4f82b38ba5607c1fc906c 119 Gene3D G3DSA:1.10.1900.20 56 119 3.8E-27 T 14-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_3194 e63ac0a726874203f431c7beabc68c63 508 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 37 445 1.3E-148 T 14-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 Tharo_3194 e63ac0a726874203f431c7beabc68c63 508 Gene3D G3DSA:2.40.50.140 56 145 1.2E-28 T 14-10-2018 Tharo_3194 e63ac0a726874203f431c7beabc68c63 508 Gene3D G3DSA:3.40.1260.20 421 507 7.6E-7 T 14-10-2018 Tharo_3194 e63ac0a726874203f431c7beabc68c63 508 SMART SM00316 61 139 3.0E-7 T 14-10-2018 IPR022967 RNA-binding domain, S1 Tharo_3194 e63ac0a726874203f431c7beabc68c63 508 Pfam PF10150 Ribonuclease E/G family 141 412 2.5E-99 T 14-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 Tharo_3194 e63ac0a726874203f431c7beabc68c63 508 SUPERFAMILY SSF50249 63 145 4.88E-18 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_1458 47b3d818c0c5e3b62815a983cea96b24 182 SMART SM00479 7 180 2.0E-24 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Tharo_1458 47b3d818c0c5e3b62815a983cea96b24 182 Hamap MF_00045 Oligoribonuclease [orn]. 3 181 43.135 T 14-10-2018 IPR022894 Oligoribonuclease GO:0000175 Tharo_1458 47b3d818c0c5e3b62815a983cea96b24 182 Gene3D G3DSA:3.30.420.10 1 182 4.5E-73 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_1458 47b3d818c0c5e3b62815a983cea96b24 182 SUPERFAMILY SSF53098 2 182 7.12E-49 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_1458 47b3d818c0c5e3b62815a983cea96b24 182 Pfam PF00929 Exonuclease 9 170 1.4E-31 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Tharo_0061 fde26d3a97cd4a2c0b8d7851e1644cb1 173 Pfam PF13404 AsnC-type helix-turn-helix domain 7 47 1.6E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Tharo_0061 fde26d3a97cd4a2c0b8d7851e1644cb1 173 Pfam PF01037 Lrp/AsnC ligand binding domain 73 145 1.1E-20 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Tharo_0061 fde26d3a97cd4a2c0b8d7851e1644cb1 173 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 1.9E-5 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Tharo_0061 fde26d3a97cd4a2c0b8d7851e1644cb1 173 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 1.9E-5 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Tharo_0061 fde26d3a97cd4a2c0b8d7851e1644cb1 173 SMART SM00344 6 115 1.6E-31 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Tharo_0061 fde26d3a97cd4a2c0b8d7851e1644cb1 173 SUPERFAMILY SSF54909 66 155 1.74E-20 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel Tharo_0061 fde26d3a97cd4a2c0b8d7851e1644cb1 173 Gene3D G3DSA:1.10.10.10 7 58 1.4E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0061 fde26d3a97cd4a2c0b8d7851e1644cb1 173 SUPERFAMILY SSF46785 2 95 4.72E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0061 fde26d3a97cd4a2c0b8d7851e1644cb1 173 Gene3D G3DSA:3.30.70.920 59 143 2.3E-26 T 14-10-2018 Tharo_2270 397aedbbc05290f18438341c27833aca 543 SMART SM00283 263 496 1.0E-69 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_2270 397aedbbc05290f18438341c27833aca 543 SUPERFAMILY SSF58104 239 497 4.71E-62 T 14-10-2018 Tharo_2270 397aedbbc05290f18438341c27833aca 543 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 383 412 6.3E-30 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_2270 397aedbbc05290f18438341c27833aca 543 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 1 24 6.3E-30 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_2270 397aedbbc05290f18438341c27833aca 543 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 354 381 6.3E-30 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_2270 397aedbbc05290f18438341c27833aca 543 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 277 306 6.3E-30 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_2270 397aedbbc05290f18438341c27833aca 543 Pfam PF12729 Four helix bundle sensory module for signal transduction 1 162 2.9E-17 T 14-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain Tharo_2270 397aedbbc05290f18438341c27833aca 543 Gene3D G3DSA:1.10.287.950 219 498 4.3E-70 T 14-10-2018 Tharo_2270 397aedbbc05290f18438341c27833aca 543 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 323 483 6.3E-33 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_1703 c1804d7dce32b4c4f07cfccc1c31dfb2 393 Pfam PF02803 Thiolase, C-terminal domain 271 391 3.9E-43 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 Tharo_1703 c1804d7dce32b4c4f07cfccc1c31dfb2 393 Pfam PF00108 Thiolase, N-terminal domain 6 261 1.1E-77 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 Tharo_1703 c1804d7dce32b4c4f07cfccc1c31dfb2 393 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 Tharo_1703 c1804d7dce32b4c4f07cfccc1c31dfb2 393 SUPERFAMILY SSF53901 271 392 8.74E-42 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_1703 c1804d7dce32b4c4f07cfccc1c31dfb2 393 Gene3D G3DSA:3.40.47.10 129 389 2.0E-137 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_1703 c1804d7dce32b4c4f07cfccc1c31dfb2 393 PIRSF PIRSF000429 1 393 3.5E-116 T 14-10-2018 IPR002155 Thiolase GO:0016747 Tharo_1703 c1804d7dce32b4c4f07cfccc1c31dfb2 393 SUPERFAMILY SSF53901 5 268 2.47E-75 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_1703 c1804d7dce32b4c4f07cfccc1c31dfb2 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 8 391 3.5E-127 T 14-10-2018 IPR002155 Thiolase GO:0016747 Tharo_1703 c1804d7dce32b4c4f07cfccc1c31dfb2 393 Gene3D G3DSA:3.40.47.10 8 276 2.0E-137 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 Tharo_1006 089c9da379ec6cb1469af222f02f34b3 250 SMART SM00967 12 88 9.2E-17 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 Tharo_1006 089c9da379ec6cb1469af222f02f34b3 250 SUPERFAMILY SSF55315 7 84 1.04E-17 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like Tharo_1006 089c9da379ec6cb1469af222f02f34b3 250 Gene3D G3DSA:3.40.1280.10 84 250 3.3E-59 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Tharo_1006 089c9da379ec6cb1469af222f02f34b3 250 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 12 84 2.1E-16 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 Tharo_1006 089c9da379ec6cb1469af222f02f34b3 250 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 11 249 5.8E-71 T 14-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 Tharo_1006 089c9da379ec6cb1469af222f02f34b3 250 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 10 250 43.332 T 14-10-2018 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB Tharo_1006 089c9da379ec6cb1469af222f02f34b3 250 Gene3D G3DSA:3.30.1330.30 3 83 3.0E-20 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like Tharo_1006 089c9da379ec6cb1469af222f02f34b3 250 Pfam PF00588 SpoU rRNA Methylase family 103 243 1.1E-39 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Tharo_1006 089c9da379ec6cb1469af222f02f34b3 250 SUPERFAMILY SSF75217 90 250 3.79E-49 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases Tharo_2996 ab26e1cd9557e069fcde8f2ff77a072a 392 SUPERFAMILY SSF103473 4 387 4.05E-54 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_2996 ab26e1cd9557e069fcde8f2ff77a072a 392 Pfam PF07690 Major Facilitator Superfamily 12 351 7.0E-37 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_2996 ab26e1cd9557e069fcde8f2ff77a072a 392 Gene3D G3DSA:1.20.1720.10 6 385 1.3E-80 T 14-10-2018 Tharo_2265 fe3a1c37b1ed1801addefc3bfc696512 438 SUPERFAMILY SSF51338 27 91 4.03E-10 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Tharo_2265 fe3a1c37b1ed1801addefc3bfc696512 438 Pfam PF01979 Amidohydrolase family 72 432 2.8E-58 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Tharo_2265 fe3a1c37b1ed1801addefc3bfc696512 438 SUPERFAMILY SSF51556 74 377 1.2E-98 T 14-10-2018 IPR032466 Metal-dependent hydrolase Tharo_2265 fe3a1c37b1ed1801addefc3bfc696512 438 Gene3D G3DSA:2.30.40.10 11 428 5.7E-178 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Tharo_2265 fe3a1c37b1ed1801addefc3bfc696512 438 TIGRFAM TIGR02967 guan_deamin: guanine deaminase 31 430 2.4E-180 T 14-10-2018 IPR014311 Guanine deaminase GO:0006147|GO:0008270|GO:0008892 KEGG: 00230+3.5.4.3|MetaCyc: PWY-5497|MetaCyc: PWY-6606|MetaCyc: PWY-6608|MetaCyc: PWY-7442|Reactome: R-HSA-74259 Tharo_2265 fe3a1c37b1ed1801addefc3bfc696512 438 Gene3D G3DSA:3.20.20.140 75 392 5.7E-178 T 14-10-2018 Tharo_1236 7ac225bfe655260f45673d4db42aa47a 348 Gene3D G3DSA:1.10.8.350 38 205 7.9E-106 T 14-10-2018 Tharo_1236 7ac225bfe655260f45673d4db42aa47a 348 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 40 332 9.5E-107 T 14-10-2018 IPR011757 Lytic transglycosylase MltB Tharo_1236 7ac225bfe655260f45673d4db42aa47a 348 Pfam PF13406 Transglycosylase SLT domain 35 330 5.2E-95 T 14-10-2018 IPR031304 Transglycosylase SLT domain 2 Tharo_1236 7ac225bfe655260f45673d4db42aa47a 348 Gene3D G3DSA:1.10.530.10 77 331 7.9E-106 T 14-10-2018 Tharo_1236 7ac225bfe655260f45673d4db42aa47a 348 SUPERFAMILY SSF53955 20 334 6.0E-87 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily Tharo_3345 443390f240a3d276dd8ff50d17a8f8ef 75 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 31 2.4E-4 T 14-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 Tharo_3345 443390f240a3d276dd8ff50d17a8f8ef 75 SUPERFAMILY SSF47598 2 53 6.95E-7 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Tharo_1092 b4fd0476ebc30fed6b76637fa2ecb9a0 467 SUPERFAMILY SSF56300 170 407 1.42E-24 T 14-10-2018 Tharo_1092 b4fd0476ebc30fed6b76637fa2ecb9a0 467 Pfam PF09423 PhoD-like phosphatase 168 407 5.8E-24 T 14-10-2018 IPR018946 Alkaline phosphatase D-related Tharo_1092 b4fd0476ebc30fed6b76637fa2ecb9a0 467 Gene3D G3DSA:3.60.21.70 162 428 2.1E-35 T 14-10-2018 IPR038607 PhoD-like superfamily Tharo_1092 b4fd0476ebc30fed6b76637fa2ecb9a0 467 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 49 126 2.0E-7 T 14-10-2018 IPR032093 Phospholipase D, N-terminal Tharo_3245 2500f54fb9cad9af841e9574c833b04f 366 Gene3D G3DSA:3.40.50.2000 170 345 1.2E-54 T 14-10-2018 Tharo_3245 2500f54fb9cad9af841e9574c833b04f 366 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 80 324 1.2E-70 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 Tharo_3245 2500f54fb9cad9af841e9574c833b04f 366 SUPERFAMILY SSF53756 13 341 2.43E-95 T 14-10-2018 Tharo_3245 2500f54fb9cad9af841e9574c833b04f 366 Gene3D G3DSA:3.40.50.2000 13 157 6.6E-50 T 14-10-2018 Tharo_3245 2500f54fb9cad9af841e9574c833b04f 366 TIGRFAM TIGR02195 heptsyl_trn_II: lipopolysaccharide heptosyltransferase II 14 342 4.3E-139 T 14-10-2018 IPR011910 ADP-heptose--LPS heptosyltransferase 2 GO:0009103|GO:0016757 Tharo_2718 0e6580f372affb3605bf6298faf7e2e4 256 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 14-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2718 0e6580f372affb3605bf6298faf7e2e4 256 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 3.7E-94 T 14-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 Tharo_2718 0e6580f372affb3605bf6298faf7e2e4 256 Gene3D G3DSA:3.30.300.20 17 107 1.3E-28 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta Tharo_2718 0e6580f372affb3605bf6298faf7e2e4 256 SUPERFAMILY SSF54814 2 106 3.4E-38 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Tharo_2718 0e6580f372affb3605bf6298faf7e2e4 256 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 1.9E-41 T 14-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2718 0e6580f372affb3605bf6298faf7e2e4 256 SUPERFAMILY SSF54821 108 206 2.75E-40 T 14-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2718 0e6580f372affb3605bf6298faf7e2e4 256 SMART SM00322 60 125 8.7E-7 T 14-10-2018 IPR004087 K Homology domain GO:0003676 Tharo_2718 0e6580f372affb3605bf6298faf7e2e4 256 Pfam PF07650 KH domain 38 110 8.3E-19 T 14-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2718 0e6580f372affb3605bf6298faf7e2e4 256 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 39.194 T 14-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 Tharo_2718 0e6580f372affb3605bf6298faf7e2e4 256 Gene3D G3DSA:3.30.1140.32 108 208 4.1E-45 T 14-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_1426 9be0273335df7c5c3915ff46452631ad 372 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 14 371 48.415 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 Tharo_1426 9be0273335df7c5c3915ff46452631ad 372 SUPERFAMILY SSF53383 15 369 1.94E-111 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_1426 9be0273335df7c5c3915ff46452631ad 372 Gene3D G3DSA:3.40.640.10 28 269 7.8E-88 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_1426 9be0273335df7c5c3915ff46452631ad 372 Pfam PF00266 Aminotransferase class-V 17 360 7.7E-51 T 14-10-2018 IPR000192 Aminotransferase class V domain Tharo_1426 9be0273335df7c5c3915ff46452631ad 372 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 17 370 1.9E-147 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 Tharo_1426 9be0273335df7c5c3915ff46452631ad 372 PIRSF PIRSF000525 10 372 1.9E-139 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 Tharo_1426 9be0273335df7c5c3915ff46452631ad 372 Gene3D G3DSA:3.90.1150.10 270 372 8.6E-38 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_3460 cf8d480bce84cc19e6378f48e5cbb936 347 Gene3D G3DSA:2.30.30.150 286 347 1.8E-32 T 14-10-2018 IPR037048 KorB, C-terminal domain superfamily GO:0003677|GO:0045892 Tharo_3460 cf8d480bce84cc19e6378f48e5cbb936 347 SUPERFAMILY SSF109709 136 244 2.35E-18 T 14-10-2018 Tharo_3460 cf8d480bce84cc19e6378f48e5cbb936 347 Pfam PF02195 ParB-like nuclease domain 50 139 3.1E-17 T 14-10-2018 IPR003115 ParB/Sulfiredoxin Tharo_3460 cf8d480bce84cc19e6378f48e5cbb936 347 SUPERFAMILY SSF110849 49 143 3.14E-14 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily Tharo_3460 cf8d480bce84cc19e6378f48e5cbb936 347 Pfam PF08535 KorB domain 161 247 4.1E-14 T 14-10-2018 IPR013741 Repressor KorB domain Tharo_3460 cf8d480bce84cc19e6378f48e5cbb936 347 Gene3D G3DSA:3.90.1530.30 61 129 6.1E-12 T 14-10-2018 Tharo_3460 cf8d480bce84cc19e6378f48e5cbb936 347 Gene3D G3DSA:1.10.10.730 133 188 3.0E-25 T 14-10-2018 Tharo_3460 cf8d480bce84cc19e6378f48e5cbb936 347 SMART SM00470 48 141 1.4E-20 T 14-10-2018 IPR003115 ParB/Sulfiredoxin Tharo_3460 cf8d480bce84cc19e6378f48e5cbb936 347 SUPERFAMILY SSF50037 289 347 4.58E-23 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal Tharo_3460 cf8d480bce84cc19e6378f48e5cbb936 347 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 46 221 3.3E-55 T 14-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 Tharo_3460 cf8d480bce84cc19e6378f48e5cbb936 347 Pfam PF06613 KorB C-terminal beta-barrel domain 289 347 1.7E-31 T 14-10-2018 IPR010575 KorB, C-terminal GO:0003677|GO:0045892 Tharo_2775 cb3e9f3a38fd3a0278970c100ad8acb2 374 Gene3D G3DSA:3.30.1490.20 9 205 5.0E-66 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Tharo_2775 cb3e9f3a38fd3a0278970c100ad8acb2 374 Gene3D G3DSA:3.30.470.20 206 361 6.0E-49 T 14-10-2018 Tharo_2775 cb3e9f3a38fd3a0278970c100ad8acb2 374 SUPERFAMILY SSF56059 19 368 5.89E-98 T 14-10-2018 Tharo_2775 cb3e9f3a38fd3a0278970c100ad8acb2 374 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 34 354 3.0E-111 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 Tharo_2254 fc79ded8f9dced485f449d99bc68d7f5 209 Pfam PF00072 Response regulator receiver domain 9 119 6.1E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2254 fc79ded8f9dced485f449d99bc68d7f5 209 SUPERFAMILY SSF46894 134 203 2.14E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_2254 fc79ded8f9dced485f449d99bc68d7f5 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2254 fc79ded8f9dced485f449d99bc68d7f5 209 Gene3D G3DSA:1.10.10.10 137 203 3.6E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2254 fc79ded8f9dced485f449d99bc68d7f5 209 SMART SM00448 7 119 2.4E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2254 fc79ded8f9dced485f449d99bc68d7f5 209 SMART SM00421 143 200 4.6E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2254 fc79ded8f9dced485f449d99bc68d7f5 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 3.8E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2254 fc79ded8f9dced485f449d99bc68d7f5 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 3.8E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2254 fc79ded8f9dced485f449d99bc68d7f5 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 3.8E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2254 fc79ded8f9dced485f449d99bc68d7f5 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 199 9.8E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2254 fc79ded8f9dced485f449d99bc68d7f5 209 SUPERFAMILY SSF52172 8 147 7.26E-33 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_2254 fc79ded8f9dced485f449d99bc68d7f5 209 Gene3D G3DSA:3.40.50.2300 2 134 9.2E-49 T 14-10-2018 Tharo_1379 8baac111d196c678356abb24c9a2b9e9 670 Gene3D G3DSA:3.30.450.40 9 470 8.7E-133 T 14-10-2018 IPR029016 GAF-like domain superfamily Tharo_1379 8baac111d196c678356abb24c9a2b9e9 670 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 499 662 5.2E-42 T 14-10-2018 IPR000160 GGDEF domain Tharo_1379 8baac111d196c678356abb24c9a2b9e9 670 Pfam PF00360 Phytochrome region 337 496 9.4E-31 T 14-10-2018 IPR013515 Phytochrome, central region GO:0006355|GO:0009584|GO:0018298 Tharo_1379 8baac111d196c678356abb24c9a2b9e9 670 Pfam PF08446 PAS fold 9 118 2.2E-10 T 14-10-2018 IPR013654 PAS fold-2 GO:0006355 Tharo_1379 8baac111d196c678356abb24c9a2b9e9 670 Gene3D G3DSA:3.30.450.320 13 245 8.7E-133 T 14-10-2018 Tharo_1379 8baac111d196c678356abb24c9a2b9e9 670 SUPERFAMILY SSF55781 333 496 1.62E-35 T 14-10-2018 Tharo_1379 8baac111d196c678356abb24c9a2b9e9 670 Gene3D G3DSA:3.30.450.270 313 487 8.7E-133 T 14-10-2018 Tharo_1379 8baac111d196c678356abb24c9a2b9e9 670 SUPERFAMILY SSF55073 508 665 6.28E-47 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_1379 8baac111d196c678356abb24c9a2b9e9 670 SUPERFAMILY SSF55785 6 117 1.17E-17 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_1379 8baac111d196c678356abb24c9a2b9e9 670 SMART SM00267 492 664 1.9E-55 T 14-10-2018 IPR000160 GGDEF domain Tharo_1379 8baac111d196c678356abb24c9a2b9e9 670 SUPERFAMILY SSF55781 126 305 1.66E-51 T 14-10-2018 Tharo_1379 8baac111d196c678356abb24c9a2b9e9 670 Pfam PF01590 GAF domain 145 298 2.2E-16 T 14-10-2018 IPR003018 GAF domain GO:0005515 Tharo_1379 8baac111d196c678356abb24c9a2b9e9 670 Pfam PF00990 Diguanylate cyclase, GGDEF domain 503 659 1.0E-42 T 14-10-2018 IPR000160 GGDEF domain Tharo_1379 8baac111d196c678356abb24c9a2b9e9 670 SMART SM00065 143 314 1.9E-5 T 14-10-2018 IPR003018 GAF domain GO:0005515 Tharo_1379 8baac111d196c678356abb24c9a2b9e9 670 PRINTS PR01033 Phytochrome signature 457 475 9.6E-14 T 14-10-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 Tharo_1379 8baac111d196c678356abb24c9a2b9e9 670 PRINTS PR01033 Phytochrome signature 423 442 9.6E-14 T 14-10-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 Tharo_1379 8baac111d196c678356abb24c9a2b9e9 670 PRINTS PR01033 Phytochrome signature 242 263 9.6E-14 T 14-10-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 Tharo_1379 8baac111d196c678356abb24c9a2b9e9 670 PRINTS PR01033 Phytochrome signature 158 177 9.6E-14 T 14-10-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 Tharo_1379 8baac111d196c678356abb24c9a2b9e9 670 Gene3D G3DSA:3.30.70.270 498 669 9.6E-54 T 14-10-2018 Tharo_1403 09d24917734888e8a316ba9c7ed65375 557 TIGRFAM TIGR03222 benzo_boxC: benzoyl-CoA-dihydrodiol lyase 10 557 1.8E-275 T 14-10-2018 IPR017633 Benzoyl-CoA-dihydrodiol lyase KEGG: 00362+4.1.2.44|MetaCyc: PWY-1361 Tharo_1403 09d24917734888e8a316ba9c7ed65375 557 Pfam PF00378 Enoyl-CoA hydratase/isomerase 51 270 3.3E-21 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Tharo_1403 09d24917734888e8a316ba9c7ed65375 557 SUPERFAMILY SSF52096 306 547 5.6E-15 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_1403 09d24917734888e8a316ba9c7ed65375 557 Gene3D G3DSA:3.90.226.10 266 492 3.0E-267 T 14-10-2018 Tharo_1403 09d24917734888e8a316ba9c7ed65375 557 Gene3D G3DSA:3.90.226.10 10 557 3.0E-267 T 14-10-2018 Tharo_1403 09d24917734888e8a316ba9c7ed65375 557 SUPERFAMILY SSF52096 19 240 1.16E-31 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_2767 0666be0fb666f07a76e11414c8f89672 614 Gene3D G3DSA:3.30.565.10 493 606 3.1E-9 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2767 0666be0fb666f07a76e11414c8f89672 614 Pfam PF07730 Histidine kinase 414 478 4.2E-9 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Tharo_0825 f1d10097f141285f4557a21b9f539997 238 Gene3D G3DSA:1.10.287.540 83 119 9.0E-7 T 14-10-2018 Tharo_0825 f1d10097f141285f4557a21b9f539997 238 PIRSF PIRSF016482 25 236 1.2E-56 T 14-10-2018 IPR007445 Pilus assembly protein, PilO Tharo_0825 f1d10097f141285f4557a21b9f539997 238 Pfam PF04350 Pilus assembly protein, PilO 75 216 2.5E-52 T 14-10-2018 IPR007445 Pilus assembly protein, PilO Tharo_0825 f1d10097f141285f4557a21b9f539997 238 Gene3D G3DSA:3.30.70.60 120 225 3.7E-34 T 14-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 Tharo_1858 ad18cf63b11ce9c97c3ccfa36a05d179 370 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 72 249 4.0E-9 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Tharo_1858 ad18cf63b11ce9c97c3ccfa36a05d179 370 Gene3D G3DSA:2.40.30.170 75 298 1.6E-27 T 14-10-2018 Tharo_1858 ad18cf63b11ce9c97c3ccfa36a05d179 370 SUPERFAMILY SSF111369 111 218 3.27E-6 T 14-10-2018 Tharo_1858 ad18cf63b11ce9c97c3ccfa36a05d179 370 Gene3D G3DSA:2.40.420.20 68 358 1.6E-27 T 14-10-2018 Tharo_1858 ad18cf63b11ce9c97c3ccfa36a05d179 370 Gene3D G3DSA:2.40.50.100 89 224 1.6E-27 T 14-10-2018 Tharo_1858 ad18cf63b11ce9c97c3ccfa36a05d179 370 Gene3D G3DSA:1.10.287.470 126 192 1.6E-27 T 14-10-2018 Tharo_3041 8e5260960e2f273d6148f3a634dff3d6 1040 SUPERFAMILY SSF56601 558 625 9.85E-7 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Tharo_3041 8e5260960e2f273d6148f3a634dff3d6 1040 SUPERFAMILY SSF56601 733 998 5.87E-29 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Tharo_3041 8e5260960e2f273d6148f3a634dff3d6 1040 Gene3D G3DSA:3.40.710.10 794 991 2.2E-15 T 14-10-2018 Tharo_3041 8e5260960e2f273d6148f3a634dff3d6 1040 SUPERFAMILY SSF53955 149 299 2.64E-7 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily Tharo_3041 8e5260960e2f273d6148f3a634dff3d6 1040 Pfam PF00912 Transglycosylase 139 342 1.8E-22 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_1551 c50ffe89f367aae49da5f911c3c1b3e4 417 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 54 300 3.7E-38 T 14-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Tharo_1551 c50ffe89f367aae49da5f911c3c1b3e4 417 Gene3D G3DSA:3.20.20.10 51 302 3.8E-101 T 14-10-2018 IPR029066 PLP-binding barrel Tharo_1551 c50ffe89f367aae49da5f911c3c1b3e4 417 TIGRFAM TIGR03099 dCO2ase_PEP1: pyridoxal-dependent decarboxylase, exosortase A system-associated 22 417 2.7E-193 T 14-10-2018 IPR017530 Pyridoxal-dependent decarboxylase, exosortase system type 1 associated Tharo_1551 c50ffe89f367aae49da5f911c3c1b3e4 417 SUPERFAMILY SSF50621 278 417 2.51E-34 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Tharo_1551 c50ffe89f367aae49da5f911c3c1b3e4 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 203 216 1.3E-9 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Tharo_1551 c50ffe89f367aae49da5f911c3c1b3e4 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 290 309 1.3E-9 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Tharo_1551 c50ffe89f367aae49da5f911c3c1b3e4 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 73 91 1.3E-9 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Tharo_1551 c50ffe89f367aae49da5f911c3c1b3e4 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 93 105 1.3E-9 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Tharo_1551 c50ffe89f367aae49da5f911c3c1b3e4 417 SUPERFAMILY SSF51419 43 302 9.45E-64 T 14-10-2018 IPR029066 PLP-binding barrel Tharo_1551 c50ffe89f367aae49da5f911c3c1b3e4 417 Gene3D G3DSA:2.40.37.10 43 417 3.8E-101 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Tharo_1551 c50ffe89f367aae49da5f911c3c1b3e4 417 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 301 395 1.4E-14 T 14-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Tharo_1551 c50ffe89f367aae49da5f911c3c1b3e4 417 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 238 255 - T 14-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site Tharo_2385 069335bdea69318a4a7fed4d3748150f 251 Gene3D G3DSA:3.40.50.720 1 251 2.1E-89 T 14-10-2018 Tharo_2385 069335bdea69318a4a7fed4d3748150f 251 SUPERFAMILY SSF69572 2 247 5.23E-83 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 Tharo_2385 069335bdea69318a4a7fed4d3748150f 251 Pfam PF00899 ThiF family 9 241 3.7E-63 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 Tharo_1768 e94866c97bf6d93e7d07ecac71b49e7b 235 Gene3D G3DSA:3.40.630.70 60 227 2.9E-68 T 14-10-2018 Tharo_1768 e94866c97bf6d93e7d07ecac71b49e7b 235 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 33 203 2.4E-76 T 14-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 Tharo_1768 e94866c97bf6d93e7d07ecac71b49e7b 235 SUPERFAMILY SSF55729 2 224 6.36E-92 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Tharo_1768 e94866c97bf6d93e7d07ecac71b49e7b 235 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 235 99.439 T 14-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 Tharo_1768 e94866c97bf6d93e7d07ecac71b49e7b 235 Gene3D G3DSA:2.30.210.20 4 59 3.2E-23 T 14-10-2018 Tharo_1768 e94866c97bf6d93e7d07ecac71b49e7b 235 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 37 212 2.7E-63 T 14-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 Tharo_1956 64b41adbd6f141f537624f663b4bc189 259 Gene3D G3DSA:3.40.390.10 144 258 7.5E-40 T 14-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 Tharo_1956 64b41adbd6f141f537624f663b4bc189 259 Pfam PF06167 Glucose-regulated metallo-peptidase M90 11 243 7.5E-85 T 14-10-2018 IPR010384 MtfA family Tharo_1956 64b41adbd6f141f537624f663b4bc189 259 Gene3D G3DSA:1.10.472.150 20 140 5.8E-39 T 14-10-2018 Tharo_1956 64b41adbd6f141f537624f663b4bc189 259 SUPERFAMILY SSF55486 38 246 2.05E-40 T 14-10-2018 Tharo_3033 ca6d1304ab6ff8e26b4f68bdf472e5f7 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 Tharo_3033 ca6d1304ab6ff8e26b4f68bdf472e5f7 260 Gene3D G3DSA:3.90.226.10 1 201 1.8E-69 T 14-10-2018 Tharo_3033 ca6d1304ab6ff8e26b4f68bdf472e5f7 260 SUPERFAMILY SSF52096 1 259 5.27E-87 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_3033 ca6d1304ab6ff8e26b4f68bdf472e5f7 260 Gene3D G3DSA:1.10.12.10 204 260 3.5E-15 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal Tharo_3033 ca6d1304ab6ff8e26b4f68bdf472e5f7 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 259 5.6E-65 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Tharo_1133 db7f8f02603355ba187527c7259f3302 416 Gene3D G3DSA:3.30.70.20 12 84 1.9E-12 T 14-10-2018 Tharo_1133 db7f8f02603355ba187527c7259f3302 416 PIRSF PIRSF000361 104 416 1.5E-76 T 14-10-2018 IPR015701 Ferredoxin--NADP reductase GO:0016491|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 Tharo_1133 db7f8f02603355ba187527c7259f3302 416 SUPERFAMILY SSF54862 15 75 1.46E-17 T 14-10-2018 Tharo_1133 db7f8f02603355ba187527c7259f3302 416 TIGRFAM TIGR03224 benzo_boxA: benzoyl-CoA oxygenase/reductase, BoxA protein 10 416 1.5E-227 T 14-10-2018 IPR017634 Benzoyl-CoA oxygenase/reductase, BoxA protein KEGG: 00362+1.14.13.208|MetaCyc: PWY-1361 Tharo_1133 db7f8f02603355ba187527c7259f3302 416 Pfam PF00970 Oxidoreductase FAD-binding domain 201 264 2.1E-4 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 Tharo_1133 db7f8f02603355ba187527c7259f3302 416 Gene3D G3DSA:3.40.50.80 262 416 5.0E-36 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_1133 db7f8f02603355ba187527c7259f3302 416 Gene3D G3DSA:2.40.30.10 122 261 4.7E-42 T 14-10-2018 Tharo_1133 db7f8f02603355ba187527c7259f3302 416 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 304 313 1.6E-18 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Tharo_1133 db7f8f02603355ba187527c7259f3302 416 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 276 295 1.6E-18 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Tharo_1133 db7f8f02603355ba187527c7259f3302 416 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 204 211 1.6E-18 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Tharo_1133 db7f8f02603355ba187527c7259f3302 416 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 240 249 1.6E-18 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Tharo_1133 db7f8f02603355ba187527c7259f3302 416 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 181 191 1.6E-18 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Tharo_1133 db7f8f02603355ba187527c7259f3302 416 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 346 362 1.6E-18 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Tharo_1133 db7f8f02603355ba187527c7259f3302 416 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 370 378 1.6E-18 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Tharo_1133 db7f8f02603355ba187527c7259f3302 416 SUPERFAMILY SSF63380 132 269 4.97E-39 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Tharo_1133 db7f8f02603355ba187527c7259f3302 416 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 21 32 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_1133 db7f8f02603355ba187527c7259f3302 416 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 50 61 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_1133 db7f8f02603355ba187527c7259f3302 416 PIRSF PIRSF501177 1 416 8.8E-218 T 14-10-2018 IPR017634 Benzoyl-CoA oxygenase/reductase, BoxA protein KEGG: 00362+1.14.13.208|MetaCyc: PWY-1361 Tharo_1133 db7f8f02603355ba187527c7259f3302 416 Pfam PF00175 Oxidoreductase NAD-binding domain 277 383 8.6E-14 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 Tharo_1133 db7f8f02603355ba187527c7259f3302 416 SUPERFAMILY SSF52343 265 416 1.83E-34 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_1133 db7f8f02603355ba187527c7259f3302 416 Pfam PF00037 4Fe-4S binding domain 44 66 1.4E-4 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_1133 db7f8f02603355ba187527c7259f3302 416 Pfam PF00037 4Fe-4S binding domain 16 37 2.1E-7 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_1288 936b5a1f920fff42c7498f1bd158eb12 698 Gene3D G3DSA:3.40.50.720 197 334 7.2E-20 T 14-10-2018 Tharo_1288 936b5a1f920fff42c7498f1bd158eb12 698 Pfam PF13380 CoA binding domain 208 339 6.7E-10 T 14-10-2018 IPR003781 CoA-binding GO:0048037 Tharo_1288 936b5a1f920fff42c7498f1bd158eb12 698 Gene3D G3DSA:3.40.50.261 335 500 3.6E-34 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_1288 936b5a1f920fff42c7498f1bd158eb12 698 SMART SM00881 203 300 0.0073 T 14-10-2018 IPR003781 CoA-binding GO:0048037 Tharo_1288 936b5a1f920fff42c7498f1bd158eb12 698 SUPERFAMILY SSF51735 196 340 2.17E-19 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1288 936b5a1f920fff42c7498f1bd158eb12 698 Gene3D G3DSA:3.40.50.261 508 691 4.0E-18 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_1288 936b5a1f920fff42c7498f1bd158eb12 698 SUPERFAMILY SSF52210 511 685 2.09E-17 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_1288 936b5a1f920fff42c7498f1bd158eb12 698 SUPERFAMILY SSF52210 361 499 3.92E-25 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_1288 936b5a1f920fff42c7498f1bd158eb12 698 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 368 498 7.5E-32 T 14-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain Tharo_0344 f1a5cb24e7f47d7b6a7d5e588a4527e5 131 Pfam PF04347 Flagellar biosynthesis protein, FliO 45 120 2.8E-16 T 14-10-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 Tharo_0344 f1a5cb24e7f47d7b6a7d5e588a4527e5 131 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 32 100 5.5E-19 T 14-10-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 Tharo_0904 0284982c3fb87fccb514c6267520694d 452 SUPERFAMILY SSF56059 83 349 3.18E-71 T 14-10-2018 Tharo_0904 0284982c3fb87fccb514c6267520694d 452 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 446 2.3E-229 T 14-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 Tharo_0904 0284982c3fb87fccb514c6267520694d 452 Gene3D G3DSA:3.30.1490.20 131 203 8.6E-154 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Tharo_0904 0284982c3fb87fccb514c6267520694d 452 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 8.5E-46 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Tharo_0904 0284982c3fb87fccb514c6267520694d 452 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 5.5E-39 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Tharo_0904 0284982c3fb87fccb514c6267520694d 452 Gene3D G3DSA:3.40.50.20 1 85 2.1E-35 T 14-10-2018 Tharo_0904 0284982c3fb87fccb514c6267520694d 452 SUPERFAMILY SSF51246 331 443 1.2E-43 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 Tharo_0904 0284982c3fb87fccb514c6267520694d 452 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Tharo_0904 0284982c3fb87fccb514c6267520694d 452 SUPERFAMILY SSF52440 1 113 6.19E-49 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Tharo_0904 0284982c3fb87fccb514c6267520694d 452 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 321 8.4E-83 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Tharo_0904 0284982c3fb87fccb514c6267520694d 452 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Tharo_0904 0284982c3fb87fccb514c6267520694d 452 SMART SM00878 336 441 3.8E-65 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Tharo_0904 0284982c3fb87fccb514c6267520694d 452 Gene3D G3DSA:3.30.470.20 87 433 8.6E-154 T 14-10-2018 Tharo_0846 172455a54778256d4b32a10f4f0abb50 506 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 328 484 3.7E-41 T 14-10-2018 IPR000160 GGDEF domain Tharo_0846 172455a54778256d4b32a10f4f0abb50 506 Gene3D G3DSA:3.30.450.20 10 147 3.5E-11 T 14-10-2018 Tharo_0846 172455a54778256d4b32a10f4f0abb50 506 SMART SM00267 320 490 5.4E-47 T 14-10-2018 IPR000160 GGDEF domain Tharo_0846 172455a54778256d4b32a10f4f0abb50 506 Gene3D G3DSA:3.30.70.270 325 489 3.1E-49 T 14-10-2018 Tharo_0846 172455a54778256d4b32a10f4f0abb50 506 Pfam PF00990 Diguanylate cyclase, GGDEF domain 330 482 2.4E-40 T 14-10-2018 IPR000160 GGDEF domain Tharo_0846 172455a54778256d4b32a10f4f0abb50 506 SUPERFAMILY SSF55073 335 485 1.49E-41 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_3252 159b1f9ea07f6b3ee9df0815c0d31c4d 138 SUPERFAMILY SSF46626 32 137 1.53E-31 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_3252 159b1f9ea07f6b3ee9df0815c0d31c4d 138 Gene3D G3DSA:1.10.760.10 22 138 2.4E-44 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_3252 159b1f9ea07f6b3ee9df0815c0d31c4d 138 Pfam PF09086 Domain of unknown function (DUF1924) 42 135 1.6E-36 T 14-10-2018 IPR015170 Protein of unknown function DUF1924 Tharo_1946 bb9e54d45fd453d1af3b506fd4b84048 321 SUPERFAMILY SSF143865 2 253 3.53E-67 T 14-10-2018 Tharo_1946 bb9e54d45fd453d1af3b506fd4b84048 321 Pfam PF01544 CorA-like Mg2+ transporter protein 30 317 1.9E-64 T 14-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 Tharo_1946 bb9e54d45fd453d1af3b506fd4b84048 321 Gene3D G3DSA:3.30.460.20 2 130 5.7E-27 T 14-10-2018 Tharo_1946 bb9e54d45fd453d1af3b506fd4b84048 321 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 21 321 1.2E-65 T 14-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 Tharo_1946 bb9e54d45fd453d1af3b506fd4b84048 321 SUPERFAMILY SSF144083 257 318 7.59E-17 T 14-10-2018 Tharo_1946 bb9e54d45fd453d1af3b506fd4b84048 321 Gene3D G3DSA:1.20.58.340 245 321 2.2E-21 T 14-10-2018 Tharo_1946 bb9e54d45fd453d1af3b506fd4b84048 321 Gene3D G3DSA:1.20.58.340 131 242 4.7E-34 T 14-10-2018 Tharo_1821 87420d2e89705e3293c7cef11570fdf8 249 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 14-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 Tharo_1821 87420d2e89705e3293c7cef11570fdf8 249 Gene3D G3DSA:3.40.50.620 1 248 7.5E-88 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_1821 87420d2e89705e3293c7cef11570fdf8 249 Pfam PF01012 Electron transfer flavoprotein domain 29 206 3.8E-45 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 Tharo_1821 87420d2e89705e3293c7cef11570fdf8 249 PIRSF PIRSF000090 1 249 2.8E-85 T 14-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 Tharo_1821 87420d2e89705e3293c7cef11570fdf8 249 SMART SM00893 23 211 8.9E-70 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 Tharo_1821 87420d2e89705e3293c7cef11570fdf8 249 SUPERFAMILY SSF52402 1 242 3.49E-84 T 14-10-2018 Tharo_2940 ecf6589a92990a98dcb12808902cb33f 487 Gene3D G3DSA:3.40.309.10 257 444 2.3E-150 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Tharo_2940 ecf6589a92990a98dcb12808902cb33f 487 Pfam PF00171 Aldehyde dehydrogenase family 26 475 1.8E-150 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Tharo_2940 ecf6589a92990a98dcb12808902cb33f 487 SUPERFAMILY SSF53720 19 479 7.2E-147 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Tharo_2940 ecf6589a92990a98dcb12808902cb33f 487 Gene3D G3DSA:3.40.605.10 29 462 2.3E-150 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Tharo_2940 ecf6589a92990a98dcb12808902cb33f 487 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 Tharo_3154 129145b8689210034991e2aa58f810f7 361 Gene3D G3DSA:2.40.50.100 297 361 3.3E-12 T 14-10-2018 Tharo_3154 129145b8689210034991e2aa58f810f7 361 SUPERFAMILY SSF52540 12 227 2.54E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3154 129145b8689210034991e2aa58f810f7 361 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_3154 129145b8689210034991e2aa58f810f7 361 SMART SM00382 28 215 2.2E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_3154 129145b8689210034991e2aa58f810f7 361 Pfam PF00005 ABC transporter 28 165 3.3E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_3154 129145b8689210034991e2aa58f810f7 361 TIGRFAM TIGR02142 modC_ABC: molybdate ABC transporter, ATP-binding protein 7 360 2.2E-146 T 14-10-2018 IPR011868 Molybdate ABC transporter, ATP-binding protein GO:0005524|GO:0015098|GO:0015689|GO:0016020 Tharo_3154 129145b8689210034991e2aa58f810f7 361 Pfam PF03459 TOBE domain 298 360 8.9E-14 T 14-10-2018 IPR005116 Transport-associated OB, type 1 Tharo_3154 129145b8689210034991e2aa58f810f7 361 Gene3D G3DSA:3.40.50.300 17 235 8.0E-59 T 14-10-2018 Tharo_3154 129145b8689210034991e2aa58f810f7 361 SUPERFAMILY SSF50331 243 360 1.4E-19 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal Tharo_1169 b4893328cf8e92585390ea126edeb938 284 Gene3D G3DSA:1.10.1040.50 190 284 4.9E-34 T 14-10-2018 Tharo_1169 b4893328cf8e92585390ea126edeb938 284 Gene3D G3DSA:3.40.50.720 1 189 3.3E-73 T 14-10-2018 Tharo_1169 b4893328cf8e92585390ea126edeb938 284 PIRSF PIRSF000105 1 284 5.2E-88 T 14-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 Tharo_1169 b4893328cf8e92585390ea126edeb938 284 SUPERFAMILY SSF51735 1 185 1.08E-59 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1169 b4893328cf8e92585390ea126edeb938 284 SUPERFAMILY SSF48179 185 283 3.15E-33 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Tharo_1169 b4893328cf8e92585390ea126edeb938 284 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 183 1.1E-65 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 Tharo_1169 b4893328cf8e92585390ea126edeb938 284 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 1.2E-35 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 Tharo_0410 b6e00654f74fa16c507efa3b086f9422 541 SUPERFAMILY SSF52540 312 538 1.99E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0410 b6e00654f74fa16c507efa3b086f9422 541 SUPERFAMILY SSF52540 6 237 1.25E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0410 b6e00654f74fa16c507efa3b086f9422 541 Gene3D G3DSA:3.40.50.300 285 540 2.3E-52 T 14-10-2018 Tharo_0410 b6e00654f74fa16c507efa3b086f9422 541 Pfam PF12848 ABC transporter 224 305 1.9E-21 T 14-10-2018 IPR032781 ABC-transporter extension domain Tharo_0410 b6e00654f74fa16c507efa3b086f9422 541 Gene3D G3DSA:3.40.50.300 4 279 1.6E-59 T 14-10-2018 Tharo_0410 b6e00654f74fa16c507efa3b086f9422 541 Pfam PF00005 ABC transporter 18 184 1.6E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_0410 b6e00654f74fa16c507efa3b086f9422 541 Pfam PF00005 ABC transporter 340 477 2.4E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_0410 b6e00654f74fa16c507efa3b086f9422 541 SMART SM00382 26 238 1.0E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0410 b6e00654f74fa16c507efa3b086f9422 541 SMART SM00382 348 530 9.8E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2231 7dbdd66b23142f640d12b90232a2a4f4 549 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 81 91 - T 14-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site Tharo_2231 7dbdd66b23142f640d12b90232a2a4f4 549 Gene3D G3DSA:3.40.50.200 41 397 1.6E-91 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 Tharo_2231 7dbdd66b23142f640d12b90232a2a4f4 549 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 325 335 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site Tharo_2231 7dbdd66b23142f640d12b90232a2a4f4 549 SUPERFAMILY SSF52743 42 389 1.7E-66 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 Tharo_2231 7dbdd66b23142f640d12b90232a2a4f4 549 PRINTS PR00723 Subtilisin serine protease family (S8) signature 76 95 4.9E-13 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Tharo_2231 7dbdd66b23142f640d12b90232a2a4f4 549 PRINTS PR00723 Subtilisin serine protease family (S8) signature 324 340 4.9E-13 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Tharo_2231 7dbdd66b23142f640d12b90232a2a4f4 549 PRINTS PR00723 Subtilisin serine protease family (S8) signature 141 154 4.9E-13 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Tharo_2231 7dbdd66b23142f640d12b90232a2a4f4 549 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 145 155 - T 14-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site Tharo_2231 7dbdd66b23142f640d12b90232a2a4f4 549 Pfam PF00082 Subtilase family 77 362 5.8E-40 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Tharo_1602 c0cdac6f012f3ae96b4390250fa8b5c8 309 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 289 2.3E-105 T 14-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 Tharo_1602 c0cdac6f012f3ae96b4390250fa8b5c8 309 SUPERFAMILY SSF55048 126 195 1.31E-18 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding Tharo_1602 c0cdac6f012f3ae96b4390250fa8b5c8 309 Pfam PF00698 Acyl transferase domain 6 293 9.4E-33 T 14-10-2018 IPR014043 Acyl transferase Tharo_1602 c0cdac6f012f3ae96b4390250fa8b5c8 309 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 305 1.8E-32 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain Tharo_1602 c0cdac6f012f3ae96b4390250fa8b5c8 309 Gene3D G3DSA:3.30.70.250 123 195 3.3E-95 T 14-10-2018 Tharo_1602 c0cdac6f012f3ae96b4390250fa8b5c8 309 SUPERFAMILY SSF52151 3 304 4.45E-73 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase Tharo_1602 c0cdac6f012f3ae96b4390250fa8b5c8 309 PIRSF PIRSF000446 1 308 6.3E-108 T 14-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 Tharo_1602 c0cdac6f012f3ae96b4390250fa8b5c8 309 Gene3D G3DSA:3.40.366.10 4 282 3.3E-95 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 Tharo_1572 5f711478b258d03f072f9e1edaae0d56 188 Hamap MF_00146 dCTP deaminase [dcd]. 1 188 28.871 T 14-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 Tharo_1572 5f711478b258d03f072f9e1edaae0d56 188 SUPERFAMILY SSF51283 3 188 3.14E-51 T 14-10-2018 IPR036157 dUTPase-like superfamily Tharo_1572 5f711478b258d03f072f9e1edaae0d56 188 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 4 188 1.2E-49 T 14-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 Tharo_1572 5f711478b258d03f072f9e1edaae0d56 188 Pfam PF00692 dUTPase 82 181 1.8E-6 T 14-10-2018 IPR029054 dUTPase-like Tharo_1572 5f711478b258d03f072f9e1edaae0d56 188 Gene3D G3DSA:2.70.40.10 1 160 7.8E-52 T 14-10-2018 IPR036157 dUTPase-like superfamily Tharo_0294 8686a5b4737511ccddc56705b6a9aeb5 305 SMART SM00342 220 303 1.1E-25 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Tharo_0294 8686a5b4737511ccddc56705b6a9aeb5 305 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 272 287 3.6E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Tharo_0294 8686a5b4737511ccddc56705b6a9aeb5 305 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 287 303 3.6E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Tharo_0294 8686a5b4737511ccddc56705b6a9aeb5 305 Gene3D G3DSA:1.10.10.60 207 305 7.7E-23 T 14-10-2018 Tharo_0294 8686a5b4737511ccddc56705b6a9aeb5 305 SUPERFAMILY SSF46689 257 304 2.33E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_0294 8686a5b4737511ccddc56705b6a9aeb5 305 SUPERFAMILY SSF46689 204 250 5.02E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_0294 8686a5b4737511ccddc56705b6a9aeb5 305 Pfam PF12833 Helix-turn-helix domain 226 304 3.5E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Tharo_0294 8686a5b4737511ccddc56705b6a9aeb5 305 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 257 299 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Tharo_1172 843d832ec41968c67069f20e2b430f10 107 Pfam PF00037 4Fe-4S binding domain 34 55 1.9E-7 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_1172 843d832ec41968c67069f20e2b430f10 107 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_1172 843d832ec41968c67069f20e2b430f10 107 SUPERFAMILY SSF54862 1 97 7.48E-25 T 14-10-2018 Tharo_1172 843d832ec41968c67069f20e2b430f10 107 Pfam PF11953 Domain of unknown function (DUF3470) 66 107 1.1E-18 T 14-10-2018 IPR022569 Ferredoxin, C-terminal Tharo_1172 843d832ec41968c67069f20e2b430f10 107 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.1E-14 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 Tharo_1172 843d832ec41968c67069f20e2b430f10 107 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.1E-14 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 Tharo_1172 843d832ec41968c67069f20e2b430f10 107 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.1E-14 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 Tharo_1172 843d832ec41968c67069f20e2b430f10 107 Gene3D G3DSA:3.30.70.20 2 101 1.5E-31 T 14-10-2018 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 Gene3D G3DSA:3.30.420.40 22 377 7.9E-113 T 14-10-2018 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 Gene3D G3DSA:1.20.1270.10 525 619 2.6E-29 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 Gene3D G3DSA:3.90.640.10 237 314 7.9E-113 T 14-10-2018 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 335 349 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 SUPERFAMILY SSF100920 386 540 1.23E-47 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 SUPERFAMILY SSF53067 199 380 2.38E-50 T 14-10-2018 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 Hamap MF_00679 Chaperone protein HscA [hscA]. 1 620 43.499 T 14-10-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 24 31 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 204 217 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 Gene3D G3DSA:3.30.420.40 193 364 7.9E-113 T 14-10-2018 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 Pfam PF00012 Hsp70 protein 21 603 5.6E-177 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 Gene3D G3DSA:2.60.34.10 383 524 1.8E-45 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 SUPERFAMILY SSF53067 19 195 2.78E-51 T 14-10-2018 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 PRINTS PR00301 70kDa heat shock protein signature 20 33 1.0E-52 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 PRINTS PR00301 70kDa heat shock protein signature 332 348 1.0E-52 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 PRINTS PR00301 70kDa heat shock protein signature 389 408 1.0E-52 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 PRINTS PR00301 70kDa heat shock protein signature 363 383 1.0E-52 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 PRINTS PR00301 70kDa heat shock protein signature 470 486 1.0E-52 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 PRINTS PR00301 70kDa heat shock protein signature 151 171 1.0E-52 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 PRINTS PR00301 70kDa heat shock protein signature 210 220 1.0E-52 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 SUPERFAMILY SSF100934 508 619 5.69E-37 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 Tharo_2083 d651ee3c1bd53f89e8249622b53a03d1 622 TIGRFAM TIGR01991 HscA: Fe-S protein assembly chaperone HscA 21 619 3.1E-275 T 14-10-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 Tharo_2300 241b320259c80719605a915fc1173098 834 SUPERFAMILY SSF56784 523 820 1.16E-45 T 14-10-2018 IPR036412 HAD-like superfamily Tharo_2300 241b320259c80719605a915fc1173098 834 Pfam PF00702 haloacid dehalogenase-like hydrolase 521 733 1.1E-25 T 14-10-2018 Tharo_2300 241b320259c80719605a915fc1173098 834 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 376 390 9.1E-20 T 14-10-2018 Tharo_2300 241b320259c80719605a915fc1173098 834 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 524 538 9.1E-20 T 14-10-2018 Tharo_2300 241b320259c80719605a915fc1173098 834 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 720 739 9.1E-20 T 14-10-2018 Tharo_2300 241b320259c80719605a915fc1173098 834 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 743 755 9.1E-20 T 14-10-2018 Tharo_2300 241b320259c80719605a915fc1173098 834 Gene3D G3DSA:2.70.150.20 316 430 9.3E-31 T 14-10-2018 Tharo_2300 241b320259c80719605a915fc1173098 834 Pfam PF00403 Heavy-metal-associated domain 112 169 1.6E-10 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 Tharo_2300 241b320259c80719605a915fc1173098 834 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 261 822 4.6E-157 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Tharo_2300 241b320259c80719605a915fc1173098 834 Gene3D G3DSA:3.30.70.100 105 189 3.5E-14 T 14-10-2018 Tharo_2300 241b320259c80719605a915fc1173098 834 ProSitePatterns PS01229 Hypothetical cof family signature 2. 720 742 - T 14-10-2018 Tharo_2300 241b320259c80719605a915fc1173098 834 Gene3D G3DSA:3.40.1110.10 535 651 5.3E-67 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Tharo_2300 241b320259c80719605a915fc1173098 834 Pfam PF12156 Putative metal-binding domain of cation transport ATPase 18 100 2.9E-26 T 14-10-2018 IPR021993 Putative metal-binding domain of cation transport ATPase Tharo_2300 241b320259c80719605a915fc1173098 834 Pfam PF00122 E1-E2 ATPase 340 503 7.8E-49 T 14-10-2018 Tharo_2300 241b320259c80719605a915fc1173098 834 SUPERFAMILY SSF81665 283 799 2.75E-15 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 Tharo_2300 241b320259c80719605a915fc1173098 834 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 622 802 4.2E-33 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Tharo_2300 241b320259c80719605a915fc1173098 834 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 337 545 2.4E-38 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Tharo_2300 241b320259c80719605a915fc1173098 834 SUPERFAMILY SSF81653 340 426 6.41E-23 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Tharo_2300 241b320259c80719605a915fc1173098 834 Gene3D G3DSA:3.40.50.1000 505 772 5.3E-67 T 14-10-2018 IPR023214 HAD superfamily Tharo_2300 241b320259c80719605a915fc1173098 834 SUPERFAMILY SSF55008 102 177 3.01E-18 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 Tharo_2300 241b320259c80719605a915fc1173098 834 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 243 823 3.2E-146 T 14-10-2018 Tharo_2300 241b320259c80719605a915fc1173098 834 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 526 532 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Tharo_2847 547d4ecd12042a74af6366fc46578624 334 PIRSF PIRSF018266 19 333 7.4E-85 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component Tharo_2847 547d4ecd12042a74af6366fc46578624 334 Gene3D G3DSA:2.60.120.1440 114 246 6.3E-17 T 14-10-2018 Tharo_2847 547d4ecd12042a74af6366fc46578624 334 Pfam PF16220 Domain of unknown function (DUF4880) 28 69 1.2E-10 T 14-10-2018 IPR032623 FecR, N-terminal Tharo_2847 547d4ecd12042a74af6366fc46578624 334 Pfam PF04773 FecR protein 126 219 6.9E-17 T 14-10-2018 IPR006860 FecR protein Tharo_2921 1d8c940e1d4d0e1b146e167e442d7554 293 Pfam PF13242 HAD-hyrolase-like 209 283 3.5E-7 T 14-10-2018 Tharo_2921 1d8c940e1d4d0e1b146e167e442d7554 293 SUPERFAMILY SSF56784 25 285 7.64E-39 T 14-10-2018 IPR036412 HAD-like superfamily Tharo_2921 1d8c940e1d4d0e1b146e167e442d7554 293 Pfam PF13344 Haloacid dehalogenase-like hydrolase 27 131 3.8E-23 T 14-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA Tharo_2921 1d8c940e1d4d0e1b146e167e442d7554 293 Gene3D G3DSA:3.40.50.1000 26 262 1.3E-49 T 14-10-2018 IPR023214 HAD superfamily Tharo_2921 1d8c940e1d4d0e1b146e167e442d7554 293 Gene3D G3DSA:3.40.50.1000 110 209 1.3E-49 T 14-10-2018 IPR023214 HAD superfamily Tharo_3335 02f05f0e670d6adfdad90cdb35ddf1a3 249 Pfam PF02390 Putative methyltransferase 75 242 4.3E-54 T 14-10-2018 Tharo_3335 02f05f0e670d6adfdad90cdb35ddf1a3 249 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 60 247 1.4E-54 T 14-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 Tharo_3335 02f05f0e670d6adfdad90cdb35ddf1a3 249 Gene3D G3DSA:3.40.50.150 41 248 2.5E-68 T 14-10-2018 Tharo_3335 02f05f0e670d6adfdad90cdb35ddf1a3 249 SUPERFAMILY SSF53335 29 247 1.84E-43 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_3335 02f05f0e670d6adfdad90cdb35ddf1a3 249 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 35 247 30.076 T 14-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 Tharo_0067 22706d37e7b49c7163a211d30d1713e9 2035 Gene3D G3DSA:1.20.1580.10 122 541 1.2E-219 T 14-10-2018 Tharo_0067 22706d37e7b49c7163a211d30d1713e9 2035 Gene3D G3DSA:3.40.50.300 1143 1257 1.1E-24 T 14-10-2018 Tharo_0067 22706d37e7b49c7163a211d30d1713e9 2035 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 36 898 6.6E-248 T 14-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 Tharo_0067 22706d37e7b49c7163a211d30d1713e9 2035 Gene3D G3DSA:3.40.50.300 1416 1655 7.2E-57 T 14-10-2018 Tharo_0067 22706d37e7b49c7163a211d30d1713e9 2035 SUPERFAMILY SSF52540 1671 1999 6.12E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0067 22706d37e7b49c7163a211d30d1713e9 2035 Gene3D G3DSA:1.20.1580.10 1765 1903 1.7E-130 T 14-10-2018 Tharo_0067 22706d37e7b49c7163a211d30d1713e9 2035 Gene3D G3DSA:1.20.1580.10 741 875 1.7E-54 T 14-10-2018 Tharo_0067 22706d37e7b49c7163a211d30d1713e9 2035 Gene3D G3DSA:3.40.50.300 1674 2025 1.7E-130 T 14-10-2018 Tharo_0067 22706d37e7b49c7163a211d30d1713e9 2035 SUPERFAMILY SSF52540 1157 1627 2.87E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0067 22706d37e7b49c7163a211d30d1713e9 2035 ProSitePatterns PS00211 ABC transporters family signature. 1545 1559 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_0067 22706d37e7b49c7163a211d30d1713e9 2035 Gene3D G3DSA:3.30.190.20 162 271 1.2E-219 T 14-10-2018 Tharo_0067 22706d37e7b49c7163a211d30d1713e9 2035 ProSitePatterns PS00211 ABC transporters family signature. 1903 1917 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_0067 22706d37e7b49c7163a211d30d1713e9 2035 Gene3D G3DSA:3.40.50.300 38 643 1.2E-219 T 14-10-2018 Tharo_0067 22706d37e7b49c7163a211d30d1713e9 2035 Gene3D G3DSA:1.10.8.280 321 429 1.2E-219 T 14-10-2018 Tharo_0067 22706d37e7b49c7163a211d30d1713e9 2035 SUPERFAMILY SSF52540 664 894 8.49E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0067 22706d37e7b49c7163a211d30d1713e9 2035 Gene3D G3DSA:3.30.190.20 1277 1402 1.3E-27 T 14-10-2018 Tharo_0067 22706d37e7b49c7163a211d30d1713e9 2035 SUPERFAMILY SSF52540 961 1046 4.66E-13 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0067 22706d37e7b49c7163a211d30d1713e9 2035 SUPERFAMILY SSF52540 36 628 7.41E-31 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1910 d630af880e8dc01fe3d353f9b864ac10 126 SMART SM00418 8 89 7.6E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Tharo_1910 d630af880e8dc01fe3d353f9b864ac10 126 Pfam PF12840 Helix-turn-helix domain 8 69 3.1E-15 T 14-10-2018 Tharo_1910 d630af880e8dc01fe3d353f9b864ac10 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 2.3E-5 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Tharo_1910 d630af880e8dc01fe3d353f9b864ac10 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 2.3E-5 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Tharo_1910 d630af880e8dc01fe3d353f9b864ac10 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 2.3E-5 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Tharo_1910 d630af880e8dc01fe3d353f9b864ac10 126 Gene3D G3DSA:1.10.10.10 1 93 2.4E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1910 d630af880e8dc01fe3d353f9b864ac10 126 SUPERFAMILY SSF46785 5 93 2.98E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_2436 2d813182ab0fb44d5a8bd8234fdb4180 1301 SUPERFAMILY SSF52540 21 879 1.65E-107 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2436 2d813182ab0fb44d5a8bd8234fdb4180 1301 Gene3D G3DSA:1.10.486.10 638 783 2.8E-138 T 14-10-2018 Tharo_2436 2d813182ab0fb44d5a8bd8234fdb4180 1301 Gene3D G3DSA:1.10.3170.10 183 389 1.4E-130 T 14-10-2018 Tharo_2436 2d813182ab0fb44d5a8bd8234fdb4180 1301 Pfam PF13361 UvrD-like helicase C-terminal domain 737 875 5.3E-14 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Tharo_2436 2d813182ab0fb44d5a8bd8234fdb4180 1301 Pfam PF00580 UvrD/REP helicase N-terminal domain 25 478 1.8E-49 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 Tharo_2436 2d813182ab0fb44d5a8bd8234fdb4180 1301 SUPERFAMILY SSF52980 967 1289 4.13E-61 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Tharo_2436 2d813182ab0fb44d5a8bd8234fdb4180 1301 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1166 1265 6.3E-5 T 14-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type Tharo_2436 2d813182ab0fb44d5a8bd8234fdb4180 1301 Gene3D G3DSA:3.90.320.10 960 1298 2.4E-70 T 14-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal Tharo_2436 2d813182ab0fb44d5a8bd8234fdb4180 1301 Gene3D G3DSA:3.40.50.300 20 479 1.4E-130 T 14-10-2018 Tharo_2436 2d813182ab0fb44d5a8bd8234fdb4180 1301 TIGRFAM TIGR00609 recB: exodeoxyribonuclease V, beta subunit 20 1270 2.9E-269 T 14-10-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 Tharo_2436 2d813182ab0fb44d5a8bd8234fdb4180 1301 Gene3D G3DSA:3.40.50.300 489 900 2.8E-138 T 14-10-2018 Tharo_2436 2d813182ab0fb44d5a8bd8234fdb4180 1301 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 18 1292 20.576 T 14-10-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 Tharo_0261 1e8bb2f1e6f1c9d6d26a2d8ac26f9dcb 218 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 12 204 3.2E-64 T 14-10-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004 Tharo_0261 1e8bb2f1e6f1c9d6d26a2d8ac26f9dcb 218 Pfam PF00005 ABC transporter 28 169 3.6E-21 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_0261 1e8bb2f1e6f1c9d6d26a2d8ac26f9dcb 218 SMART SM00382 36 217 4.5E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0261 1e8bb2f1e6f1c9d6d26a2d8ac26f9dcb 218 Gene3D G3DSA:3.40.50.300 3 214 9.3E-40 T 14-10-2018 Tharo_0261 1e8bb2f1e6f1c9d6d26a2d8ac26f9dcb 218 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_0261 1e8bb2f1e6f1c9d6d26a2d8ac26f9dcb 218 SUPERFAMILY SSF52540 10 200 1.93E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1568 839fb785a7c2957e8ca354908d284be2 563 Pfam PF00916 Sulfate permease family 21 373 3.7E-87 T 14-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 Tharo_1568 839fb785a7c2957e8ca354908d284be2 563 Gene3D G3DSA:3.30.750.24 438 548 1.7E-25 T 14-10-2018 IPR036513 STAS domain superfamily Tharo_1568 839fb785a7c2957e8ca354908d284be2 563 Pfam PF01740 STAS domain 444 540 1.3E-12 T 14-10-2018 IPR002645 STAS domain Tharo_1568 839fb785a7c2957e8ca354908d284be2 563 SUPERFAMILY SSF52091 447 547 2.35E-16 T 14-10-2018 IPR036513 STAS domain superfamily Tharo_0369 d0142ef33fc2f989c69c8cc3243fa1a8 550 SUPERFAMILY SSF53335 20 181 5.47E-27 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_0369 d0142ef33fc2f989c69c8cc3243fa1a8 550 Pfam PF13847 Methyltransferase domain 58 163 1.2E-13 T 14-10-2018 IPR025714 Methyltransferase domain Tharo_0369 d0142ef33fc2f989c69c8cc3243fa1a8 550 Gene3D G3DSA:3.40.50.150 16 261 2.6E-23 T 14-10-2018 Tharo_0369 d0142ef33fc2f989c69c8cc3243fa1a8 550 Pfam PF10119 Predicted methyltransferase regulatory domain 228 312 3.8E-23 T 14-10-2018 IPR018773 Methyltransferase regulatory domain, predicted Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 Pfam PF03764 Elongation factor G, domain IV 484 604 3.6E-49 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 Gene3D G3DSA:3.30.230.10 489 694 2.7E-90 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 Pfam PF00679 Elongation factor G C-terminus 606 692 2.1E-32 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 Hamap MF_00054_B Elongation factor G [fusA]. 6 698 111.986 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 Gene3D G3DSA:3.30.70.870 438 488 2.8E-26 T 14-10-2018 Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 TIGRFAM TIGR00484 EF-G: translation elongation factor G 2 699 0.0 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 1.5E-63 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.3E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 PRINTS PR00315 GTP-binding elongation factor signature 101 112 4.3E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 PRINTS PR00315 GTP-binding elongation factor signature 137 146 4.3E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 PRINTS PR00315 GTP-binding elongation factor signature 85 95 4.3E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.3E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 SUPERFAMILY SSF54980 609 697 1.1E-30 T 14-10-2018 IPR035647 EF-G domain III/V-like Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 SUPERFAMILY SSF50447 271 407 2.59E-35 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 SUPERFAMILY SSF52540 6 288 6.04E-106 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 SUPERFAMILY SSF54980 409 486 1.91E-25 T 14-10-2018 IPR035647 EF-G domain III/V-like Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 SMART SM00889 485 604 9.3E-76 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 Gene3D G3DSA:3.40.50.300 1 293 1.4E-109 T 14-10-2018 Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 SUPERFAMILY SSF54211 484 605 1.74E-44 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 Pfam PF14492 Elongation Factor G, domain II 409 482 4.3E-34 T 14-10-2018 Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 Gene3D G3DSA:3.30.70.240 610 681 2.7E-90 T 14-10-2018 Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 Gene3D G3DSA:2.40.30.10 294 421 8.2E-51 T 14-10-2018 Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 SMART SM00838 606 694 2.0E-56 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 Pfam PF03144 Elongation factor Tu domain 2 329 396 3.2E-17 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Tharo_2727 a5717cac85195e7b9b452e1c69486648 699 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 186 7.5E-30 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Tharo_0178 bc0a343faa8707de0111703507489a73 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.3E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_0178 bc0a343faa8707de0111703507489a73 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.3E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_0178 bc0a343faa8707de0111703507489a73 213 SUPERFAMILY SSF46689 10 90 1.3E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_0178 bc0a343faa8707de0111703507489a73 213 Gene3D G3DSA:1.10.357.10 20 210 1.1E-30 T 14-10-2018 Tharo_0178 bc0a343faa8707de0111703507489a73 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 2.1E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_0251 8e6d64c013e22edd24cc2bc8ed1631ff 400 Pfam PF10442 FIST C domain 224 376 1.3E-28 T 14-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 Tharo_0251 8e6d64c013e22edd24cc2bc8ed1631ff 400 PIRSF PIRSF018953 2 395 3.7E-49 T 14-10-2018 IPR016741 Uncharacterised conserved protein UCP018953 Tharo_0251 8e6d64c013e22edd24cc2bc8ed1631ff 400 Pfam PF08495 FIST N domain 45 221 1.8E-27 T 14-10-2018 IPR013702 FIST domain, N-terminal Tharo_0251 8e6d64c013e22edd24cc2bc8ed1631ff 400 SMART SM00897 42 222 2.1E-38 T 14-10-2018 IPR013702 FIST domain, N-terminal Tharo_0251 8e6d64c013e22edd24cc2bc8ed1631ff 400 SMART SM01204 223 377 3.1E-30 T 14-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 Tharo_3445 af377b9a549132f0fa8d1af7861e5fb0 260 SUPERFAMILY SSF103481 144 247 3.92E-18 T 14-10-2018 Tharo_3445 af377b9a549132f0fa8d1af7861e5fb0 260 Pfam PF00892 EamA-like transporter family 2 100 7.2E-9 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Tharo_3445 af377b9a549132f0fa8d1af7861e5fb0 260 Pfam PF00892 EamA-like transporter family 111 242 1.1E-21 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Tharo_3445 af377b9a549132f0fa8d1af7861e5fb0 260 SUPERFAMILY SSF103481 13 103 1.19E-11 T 14-10-2018 Tharo_0272 e540fa9f53047b9cc38d316e28ec87f8 252 Pfam PF17194 Transcriptional regulator, AbiEi antitoxin N-terminal domain 8 95 5.0E-26 T 14-10-2018 IPR033455 Transcriptional regulator AbiEi antitoxin, N-terminal domain Tharo_0272 e540fa9f53047b9cc38d316e28ec87f8 252 Pfam PF11459 Transcriptional regulator, AbiEi antitoxin, Type IV TA system 99 245 2.8E-38 T 14-10-2018 IPR021561 Transcriptional regulator, AbiEi 3 antitoxin, Type IV TA system Tharo_2593 ef946c71b70760fe8df7bded475ec4f5 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 5.0E-42 T 14-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2593 ef946c71b70760fe8df7bded475ec4f5 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 8.1E-38 T 14-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2593 ef946c71b70760fe8df7bded475ec4f5 103 SUPERFAMILY SSF141091 1 102 7.32E-40 T 14-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2593 ef946c71b70760fe8df7bded475ec4f5 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 14-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2593 ef946c71b70760fe8df7bded475ec4f5 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 27.518 T 14-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2777 33e3e0f5aecc322589bdfee4693b6023 472 SUPERFAMILY SSF50475 1 304 4.71E-83 T 14-10-2018 Tharo_2777 33e3e0f5aecc322589bdfee4693b6023 472 TIGRFAM TIGR02724 phenyl_P_beta: phenylphosphate carboxylase, beta subunit 1 472 0.0 T 14-10-2018 IPR014096 Phenylphosphate carboxylase, beta subunit Tharo_2777 33e3e0f5aecc322589bdfee4693b6023 472 SUPERFAMILY SSF143968 308 471 3.53E-39 T 14-10-2018 Tharo_2777 33e3e0f5aecc322589bdfee4693b6023 472 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 3 439 2.6E-93 T 14-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 Tharo_2777 33e3e0f5aecc322589bdfee4693b6023 472 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 7 413 3.2E-112 T 14-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 Tharo_2777 33e3e0f5aecc322589bdfee4693b6023 472 Gene3D G3DSA:3.40.1670.10 321 440 7.3E-25 T 14-10-2018 Tharo_1665 ff271a0ec9880468d37787efb10ab05c 382 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 36 369 2.2E-142 T 14-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 Tharo_1665 ff271a0ec9880468d37787efb10ab05c 382 Gene3D G3DSA:3.30.70.20 219 280 6.2E-6 T 14-10-2018 Tharo_1665 ff271a0ec9880468d37787efb10ab05c 382 Pfam PF08331 Domain of unknown function (DUF1730) 84 161 1.4E-22 T 14-10-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 Tharo_1665 ff271a0ec9880468d37787efb10ab05c 382 Pfam PF13484 4Fe-4S double cluster binding domain 213 277 9.7E-20 T 14-10-2018 Tharo_1665 ff271a0ec9880468d37787efb10ab05c 382 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 214 225 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_1665 ff271a0ec9880468d37787efb10ab05c 382 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 29 336 48.088 T 14-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 Tharo_1665 ff271a0ec9880468d37787efb10ab05c 382 SUPERFAMILY SSF46548 184 277 3.66E-18 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Tharo_2438 99c3c874cb155b6962bb30a2773668a4 311 Pfam PF01259 SAICAR synthetase 16 282 7.3E-95 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Tharo_2438 99c3c874cb155b6962bb30a2773668a4 311 Gene3D G3DSA:3.30.470.20 106 263 4.8E-54 T 14-10-2018 Tharo_2438 99c3c874cb155b6962bb30a2773668a4 311 ProSitePatterns PS01058 SAICAR synthetase signature 2. 219 227 - T 14-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Tharo_2438 99c3c874cb155b6962bb30a2773668a4 311 SUPERFAMILY SSF56104 5 309 3.07E-98 T 14-10-2018 Tharo_2438 99c3c874cb155b6962bb30a2773668a4 311 Gene3D G3DSA:3.30.200.20 4 104 3.5E-30 T 14-10-2018 Tharo_2438 99c3c874cb155b6962bb30a2773668a4 311 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 13 307 24.564 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Tharo_2438 99c3c874cb155b6962bb30a2773668a4 311 ProSitePatterns PS01057 SAICAR synthetase signature 1. 106 120 - T 14-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Tharo_2438 99c3c874cb155b6962bb30a2773668a4 311 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 16 309 9.2E-73 T 14-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 Tharo_2721 52858f16e825d5dcf02ea14d3f71d659 275 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 250 5.3E-56 T 14-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 Tharo_2721 52858f16e825d5dcf02ea14d3f71d659 275 SUPERFAMILY SSF50249 3 125 7.88E-48 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_2721 52858f16e825d5dcf02ea14d3f71d659 275 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 14-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2721 52858f16e825d5dcf02ea14d3f71d659 275 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 3.7E-34 T 14-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2721 52858f16e825d5dcf02ea14d3f71d659 275 Gene3D G3DSA:2.40.50.140 1 114 1.5E-47 T 14-10-2018 Tharo_2721 52858f16e825d5dcf02ea14d3f71d659 275 SMART SM01382 124 252 6.7E-90 T 14-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 Tharo_2721 52858f16e825d5dcf02ea14d3f71d659 275 SMART SM01383 42 118 1.1E-44 T 14-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2721 52858f16e825d5dcf02ea14d3f71d659 275 SUPERFAMILY SSF50104 126 272 7.22E-60 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily Tharo_2721 52858f16e825d5dcf02ea14d3f71d659 275 Gene3D G3DSA:2.30.30.30 118 195 2.1E-32 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 Tharo_2721 52858f16e825d5dcf02ea14d3f71d659 275 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 46.547 T 14-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Tharo_2721 52858f16e825d5dcf02ea14d3f71d659 275 Gene3D G3DSA:4.10.950.10 196 274 2.3E-35 T 14-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2721 52858f16e825d5dcf02ea14d3f71d659 275 PIRSF PIRSF002158 8 275 1.6E-102 T 14-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2721 52858f16e825d5dcf02ea14d3f71d659 275 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 4 273 6.5E-130 T 14-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Tharo_0402 3e9864ab00be1eac26bcf176249396c2 129 SUPERFAMILY SSF52172 4 125 2.56E-38 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_0402 3e9864ab00be1eac26bcf176249396c2 129 SMART SM00448 6 120 9.4E-39 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_0402 3e9864ab00be1eac26bcf176249396c2 129 Gene3D G3DSA:3.40.50.2300 1 127 1.4E-40 T 14-10-2018 Tharo_0402 3e9864ab00be1eac26bcf176249396c2 129 Pfam PF00072 Response regulator receiver domain 8 120 7.0E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_0912 79dcafb693419b1f4f890b80b6d9c7ef 274 Gene3D G3DSA:3.40.1010.10 1 105 4.5E-37 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Tharo_0912 79dcafb693419b1f4f890b80b6d9c7ef 274 Gene3D G3DSA:3.30.950.10 106 225 4.7E-39 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 Tharo_0912 79dcafb693419b1f4f890b80b6d9c7ef 274 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 1 219 33.238 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 Tharo_0912 79dcafb693419b1f4f890b80b6d9c7ef 274 PIRSF PIRSF005917 1 271 3.4E-96 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 Tharo_0912 79dcafb693419b1f4f890b80b6d9c7ef 274 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 198 4.3E-28 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Tharo_0912 79dcafb693419b1f4f890b80b6d9c7ef 274 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 1 266 1.2E-75 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 Tharo_0912 79dcafb693419b1f4f890b80b6d9c7ef 274 SUPERFAMILY SSF53790 1 217 6.94E-74 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Tharo_1331 161fc50ecfda804edf7ef4b198d0e482 242 Pfam PF04402 Protein of unknown function (DUF541) 43 236 1.7E-25 T 14-10-2018 IPR007497 Protein of unknown function DUF541 Tharo_1331 161fc50ecfda804edf7ef4b198d0e482 242 Gene3D G3DSA:3.30.70.2970 54 157 1.1E-15 T 14-10-2018 Tharo_1331 161fc50ecfda804edf7ef4b198d0e482 242 Gene3D G3DSA:3.30.110.170 45 235 1.1E-15 T 14-10-2018 Tharo_1373 57059b883ca09ee6f50a897d1b82faf9 266 SUPERFAMILY SSF52540 2 231 6.57E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1373 57059b883ca09ee6f50a897d1b82faf9 266 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 244 4.6E-109 T 14-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 Tharo_1373 57059b883ca09ee6f50a897d1b82faf9 266 SMART SM00382 26 223 1.0E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1373 57059b883ca09ee6f50a897d1b82faf9 266 Pfam PF00005 ABC transporter 17 172 1.5E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_1373 57059b883ca09ee6f50a897d1b82faf9 266 Gene3D G3DSA:3.40.50.300 1 247 5.3E-59 T 14-10-2018 Tharo_1373 57059b883ca09ee6f50a897d1b82faf9 266 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_3323 0da250af1fbe14a8efba9cdf7ecfaf2b 705 Gene3D G3DSA:1.10.760.10 602 704 4.2E-22 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_3323 0da250af1fbe14a8efba9cdf7ecfaf2b 705 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 29 562 8.6E-194 T 14-10-2018 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 Tharo_3323 0da250af1fbe14a8efba9cdf7ecfaf2b 705 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 616 689 1.1E-11 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_3323 0da250af1fbe14a8efba9cdf7ecfaf2b 705 Pfam PF13360 PQQ-like domain 474 552 2.5E-5 T 14-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat Tharo_3323 0da250af1fbe14a8efba9cdf7ecfaf2b 705 Pfam PF13360 PQQ-like domain 103 241 1.7E-17 T 14-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat Tharo_3323 0da250af1fbe14a8efba9cdf7ecfaf2b 705 SUPERFAMILY SSF46626 602 692 6.02E-18 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_3323 0da250af1fbe14a8efba9cdf7ecfaf2b 705 SUPERFAMILY SSF50998 39 620 1.7E-167 T 14-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily Tharo_3323 0da250af1fbe14a8efba9cdf7ecfaf2b 705 Gene3D G3DSA:2.140.10.10 25 599 1.8E-227 T 14-10-2018 Tharo_3323 0da250af1fbe14a8efba9cdf7ecfaf2b 705 SMART SM00564 502 534 0.014 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Tharo_3323 0da250af1fbe14a8efba9cdf7ecfaf2b 705 SMART SM00564 186 224 0.0023 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Tharo_3323 0da250af1fbe14a8efba9cdf7ecfaf2b 705 SMART SM00564 140 172 4.5E-8 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Tharo_3323 0da250af1fbe14a8efba9cdf7ecfaf2b 705 SMART SM00564 90 121 0.0019 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Tharo_2294 4fa62c6021ab90a684321b28aa571227 471 Pfam PF13746 4Fe-4S dicluster domain 212 317 1.8E-44 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_2294 4fa62c6021ab90a684321b28aa571227 471 SUPERFAMILY SSF54862 98 363 3.42E-34 T 14-10-2018 Tharo_2294 4fa62c6021ab90a684321b28aa571227 471 Pfam PF12801 4Fe-4S binding domain 88 129 1.9E-11 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_2294 4fa62c6021ab90a684321b28aa571227 471 Gene3D G3DSA:2.60.40.10 355 469 3.8E-25 T 14-10-2018 IPR013783 Immunoglobulin-like fold Tharo_2294 4fa62c6021ab90a684321b28aa571227 471 Gene3D G3DSA:3.30.70.20 209 284 8.6E-6 T 14-10-2018 Tharo_2294 4fa62c6021ab90a684321b28aa571227 471 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 34 468 5.1E-156 T 14-10-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 Tharo_2294 4fa62c6021ab90a684321b28aa571227 471 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 353 470 3.5E-27 T 14-10-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain Tharo_2294 4fa62c6021ab90a684321b28aa571227 471 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 265 276 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_0944 3287542143202ea555a8854822a6cfad 398 Gene3D G3DSA:3.40.50.150 175 397 4.3E-45 T 14-10-2018 Tharo_0944 3287542143202ea555a8854822a6cfad 398 Pfam PF13489 Methyltransferase domain 221 356 3.9E-10 T 14-10-2018 Tharo_0944 3287542143202ea555a8854822a6cfad 398 SUPERFAMILY SSF53335 178 361 1.91E-23 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_2558 60d91648654b2d91763d754c45d3f117 772 SUPERFAMILY SSF51395 403 758 1.24E-114 T 14-10-2018 Tharo_2558 60d91648654b2d91763d754c45d3f117 772 Gene3D G3DSA:3.20.20.70 405 759 1.7E-113 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_2558 60d91648654b2d91763d754c45d3f117 772 Gene3D G3DSA:3.30.9.20 40 252 3.9E-120 T 14-10-2018 Tharo_2558 60d91648654b2d91763d754c45d3f117 772 SUPERFAMILY SSF51905 1 344 3.45E-36 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_2558 60d91648654b2d91763d754c45d3f117 772 Gene3D G3DSA:3.50.50.60 3 342 3.9E-120 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_2558 60d91648654b2d91763d754c45d3f117 772 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 4.1E-10 T 14-10-2018 Tharo_2558 60d91648654b2d91763d754c45d3f117 772 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 298 4.1E-10 T 14-10-2018 Tharo_2558 60d91648654b2d91763d754c45d3f117 772 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 128 143 4.1E-10 T 14-10-2018 Tharo_2558 60d91648654b2d91763d754c45d3f117 772 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 267 282 4.1E-10 T 14-10-2018 Tharo_2558 60d91648654b2d91763d754c45d3f117 772 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 406 739 7.1E-65 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 Tharo_0552 3ab7f36336485559316783e5375e6078 310 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 308 1.7E-119 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Tharo_0552 3ab7f36336485559316783e5375e6078 310 Pfam PF14572 Phosphoribosyl synthetase-associated domain 199 308 1.5E-27 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Tharo_0552 3ab7f36336485559316783e5375e6078 310 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 2 117 2.7E-46 T 14-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Tharo_0552 3ab7f36336485559316783e5375e6078 310 Gene3D G3DSA:3.40.50.2020 3 297 3.1E-128 T 14-10-2018 Tharo_0552 3ab7f36336485559316783e5375e6078 310 SMART SM01400 1 117 7.3E-72 T 14-10-2018 Tharo_0552 3ab7f36336485559316783e5375e6078 310 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 125 140 - T 14-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 Tharo_0552 3ab7f36336485559316783e5375e6078 310 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 1 309 47.221 T 14-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 Tharo_0552 3ab7f36336485559316783e5375e6078 310 SUPERFAMILY SSF53271 65 301 4.91E-61 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Tharo_0552 3ab7f36336485559316783e5375e6078 310 Gene3D G3DSA:3.40.50.2020 144 285 3.1E-128 T 14-10-2018 Tharo_2377 bce8723583025a05ca78c537ea8fb7f2 368 Gene3D G3DSA:3.40.190.10 161 332 2.7E-123 T 14-10-2018 Tharo_2377 bce8723583025a05ca78c537ea8fb7f2 368 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 1 27 5.8E-4 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal Tharo_2377 bce8723583025a05ca78c537ea8fb7f2 368 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 48 331 6.5E-59 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 Tharo_2377 bce8723583025a05ca78c537ea8fb7f2 368 Gene3D G3DSA:3.40.190.170 41 345 2.7E-123 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily Tharo_2377 bce8723583025a05ca78c537ea8fb7f2 368 SUPERFAMILY SSF53850 140 288 2.55E-5 T 14-10-2018 Tharo_2377 bce8723583025a05ca78c537ea8fb7f2 368 PIRSF PIRSF039026 1 365 1.2E-118 T 14-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like Tharo_2011 e3c402c249aa8421e21b8e57a4499446 392 Pfam PF03781 Sulfatase-modifying factor enzyme 1 217 321 1.5E-17 T 14-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 Tharo_2011 e3c402c249aa8421e21b8e57a4499446 392 Gene3D G3DSA:3.90.1580.10 191 321 8.5E-22 T 14-10-2018 Tharo_2011 e3c402c249aa8421e21b8e57a4499446 392 Gene3D G3DSA:3.90.1580.10 322 392 1.1E-7 T 14-10-2018 Tharo_2011 e3c402c249aa8421e21b8e57a4499446 392 TIGRFAM TIGR04373 egtB_X_signatur: EgtB-related enzyme signature domain 342 391 9.2E-25 T 14-10-2018 IPR030809 EgtB-related enzyme signature domain Tharo_2011 e3c402c249aa8421e21b8e57a4499446 392 SUPERFAMILY SSF56436 201 390 9.98E-46 T 14-10-2018 IPR016187 C-type lectin fold Tharo_2011 e3c402c249aa8421e21b8e57a4499446 392 Pfam PF12867 DinB superfamily 23 152 6.9E-8 T 14-10-2018 IPR024775 DinB-like domain Tharo_3319 bccea07ddf617f38079d9b8b84587c8d 239 Pfam PF03725 3' exoribonuclease family, domain 2 158 222 2.3E-10 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Tharo_3319 bccea07ddf617f38079d9b8b84587c8d 239 Pfam PF01138 3' exoribonuclease family, domain 1 10 140 2.0E-22 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Tharo_3319 bccea07ddf617f38079d9b8b84587c8d 239 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 2.7E-113 T 14-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 Tharo_3319 bccea07ddf617f38079d9b8b84587c8d 239 ProSitePatterns PS01277 Ribonuclease PH signature. 116 129 - T 14-10-2018 IPR018336 Ribonuclease PH, conserved site Tharo_3319 bccea07ddf617f38079d9b8b84587c8d 239 Hamap MF_00564 Ribonuclease PH [rph]. 11 237 44.644 T 14-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 Tharo_3319 bccea07ddf617f38079d9b8b84587c8d 239 Gene3D G3DSA:3.30.230.70 10 237 1.5E-61 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Tharo_3319 bccea07ddf617f38079d9b8b84587c8d 239 SUPERFAMILY SSF55666 151 236 1.57E-25 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Tharo_3319 bccea07ddf617f38079d9b8b84587c8d 239 SUPERFAMILY SSF54211 1 181 4.61E-46 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_1744 e5b56d2f3a2d1510239a3a1f0c7c072c 203 SUPERFAMILY SSF48695 23 195 6.55E-62 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily Tharo_1744 e5b56d2f3a2d1510239a3a1f0c7c072c 203 PIRSF PIRSF000013 4 203 7.1E-99 T 14-10-2018 IPR024717 Denitrification system component NapC/NirT/NrfH GO:0016021|GO:0019333|GO:0020037 Tharo_1744 e5b56d2f3a2d1510239a3a1f0c7c072c 203 Gene3D G3DSA:1.10.3820.10 21 202 1.7E-40 T 14-10-2018 IPR038266 NapC/NirT cytochrome c superfamily Tharo_1744 e5b56d2f3a2d1510239a3a1f0c7c072c 203 TIGRFAM TIGR02161 napC_nirT: periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family 16 196 6.3E-97 T 14-10-2018 IPR011885 Periplasmic nitrate reductase c-type cytochrome, NapC/NirT GO:0016021|GO:0019333|GO:0020037 Tharo_1744 e5b56d2f3a2d1510239a3a1f0c7c072c 203 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 25 195 2.0E-78 T 14-10-2018 IPR005126 NapC/NirT cytochrome c, N-terminal Tharo_2723 d5371c65839e5178c3e7859261028e77 206 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 8 206 30.5 T 14-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2723 d5371c65839e5178c3e7859261028e77 206 Pfam PF00573 Ribosomal protein L4/L1 family 19 203 1.0E-56 T 14-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 Tharo_2723 d5371c65839e5178c3e7859261028e77 206 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 18 203 1.1E-65 T 14-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2723 d5371c65839e5178c3e7859261028e77 206 SUPERFAMILY SSF52166 1 205 3.79E-65 T 14-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 Tharo_2723 d5371c65839e5178c3e7859261028e77 206 Gene3D G3DSA:3.40.1370.10 2 206 4.3E-59 T 14-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 Tharo_1185 3c39023aded6a7c23fe109275dbd03f9 984 Gene3D G3DSA:1.25.40.10 515 574 1.0E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_1185 3c39023aded6a7c23fe109275dbd03f9 984 Gene3D G3DSA:1.20.58.2200 922 982 7.5E-17 T 14-10-2018 IPR038440 FimV, C-terminal domain superfamily Tharo_1185 3c39023aded6a7c23fe109275dbd03f9 984 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 180 251 7.7E-22 T 14-10-2018 IPR020012 Motility protein FimV, N-terminal Tharo_1185 3c39023aded6a7c23fe109275dbd03f9 984 TIGRFAM TIGR03504 FimV_Cterm: FimV C-terminal domain 939 982 4.1E-17 T 14-10-2018 IPR020011 Motility protein FimV, C-terminal Tharo_2595 ea1c1b21888992e1f5b0cdbe4495c1cb 395 Pfam PF01018 GTP1/OBG 5 158 3.2E-58 T 14-10-2018 IPR006169 GTP1/OBG domain Tharo_2595 ea1c1b21888992e1f5b0cdbe4495c1cb 395 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 14-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 Tharo_2595 ea1c1b21888992e1f5b0cdbe4495c1cb 395 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 333 1.3E-139 T 14-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 Tharo_2595 ea1c1b21888992e1f5b0cdbe4495c1cb 395 SUPERFAMILY SSF52540 151 337 7.48E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2595 ea1c1b21888992e1f5b0cdbe4495c1cb 395 Gene3D G3DSA:3.40.50.300 159 339 2.2E-50 T 14-10-2018 Tharo_2595 ea1c1b21888992e1f5b0cdbe4495c1cb 395 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 6.0E-35 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_2595 ea1c1b21888992e1f5b0cdbe4495c1cb 395 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 6.0E-35 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_2595 ea1c1b21888992e1f5b0cdbe4495c1cb 395 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 6.0E-35 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_2595 ea1c1b21888992e1f5b0cdbe4495c1cb 395 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 6.0E-35 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_2595 ea1c1b21888992e1f5b0cdbe4495c1cb 395 PIRSF PIRSF002401 1 379 1.4E-133 T 14-10-2018 IPR035101 GTP-binding protein, Obg-type Tharo_2595 ea1c1b21888992e1f5b0cdbe4495c1cb 395 SUPERFAMILY SSF82051 2 158 1.96E-55 T 14-10-2018 IPR036726 GTP1/OBG domain superfamily Tharo_2595 ea1c1b21888992e1f5b0cdbe4495c1cb 395 Gene3D G3DSA:2.70.210.12 1 158 1.2E-58 T 14-10-2018 IPR036726 GTP1/OBG domain superfamily Tharo_2595 ea1c1b21888992e1f5b0cdbe4495c1cb 395 Hamap MF_01454 GTPase Obg [obg]. 2 334 47.679 T 14-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 Tharo_2595 ea1c1b21888992e1f5b0cdbe4495c1cb 395 Pfam PF01926 50S ribosome-binding GTPase 161 285 8.7E-24 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_2597 761c28731c08449b97d6315b837ebfff 630 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 4 58 1.0E-20 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 Tharo_2597 761c28731c08449b97d6315b837ebfff 630 SUPERFAMILY SSF56801 2 627 9.68E-155 T 14-10-2018 Tharo_2597 761c28731c08449b97d6315b837ebfff 630 TIGRFAM TIGR02316 propion_prpE: propionate--CoA ligase 3 629 0.0 T 14-10-2018 IPR012694 Propionate--CoA ligase GO:0019629|GO:0050218 KEGG: 00640+6.2.1.17|MetaCyc: PWY-3941|MetaCyc: PWY-5104|MetaCyc: PWY-5747 Tharo_2597 761c28731c08449b97d6315b837ebfff 630 Gene3D G3DSA:3.40.50.12780 33 495 7.4E-93 T 14-10-2018 Tharo_2597 761c28731c08449b97d6315b837ebfff 630 Gene3D G3DSA:3.30.300.30 498 630 1.6E-26 T 14-10-2018 Tharo_2597 761c28731c08449b97d6315b837ebfff 630 ProSitePatterns PS00455 Putative AMP-binding domain signature. 239 250 - T 14-10-2018 IPR020845 AMP-binding, conserved site Tharo_2597 761c28731c08449b97d6315b837ebfff 630 Pfam PF13193 AMP-binding enzyme C-terminal domain 511 594 8.0E-23 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Tharo_2597 761c28731c08449b97d6315b837ebfff 630 Pfam PF00501 AMP-binding enzyme 60 502 3.2E-73 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Tharo_1160 3c73f677a43ac1acc9f0028ad600650c 326 Gene3D G3DSA:3.40.1090.20 19 111 1.2E-7 T 14-10-2018 Tharo_1160 3c73f677a43ac1acc9f0028ad600650c 326 SUPERFAMILY SSF52151 21 306 6.8E-53 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase Tharo_1160 3c73f677a43ac1acc9f0028ad600650c 326 Gene3D G3DSA:3.40.1090.10 112 207 3.8E-16 T 14-10-2018 Tharo_1160 3c73f677a43ac1acc9f0028ad600650c 326 Pfam PF01734 Patatin-like phospholipase 26 181 1.0E-19 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 Tharo_0876 bdb6d3380c51df60201f98ee3f81d45e 409 SMART SM00363 171 231 1.2E-6 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_0876 bdb6d3380c51df60201f98ee3f81d45e 409 Gene3D G3DSA:3.10.290.10 167 223 2.7E-17 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Tharo_0876 bdb6d3380c51df60201f98ee3f81d45e 409 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 273 404 6.1E-39 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 Tharo_0876 bdb6d3380c51df60201f98ee3f81d45e 409 SUPERFAMILY SSF55174 171 253 2.75E-15 T 14-10-2018 Tharo_0876 bdb6d3380c51df60201f98ee3f81d45e 409 Gene3D G3DSA:3.30.2350.10 226 409 7.6E-45 T 14-10-2018 Tharo_0876 bdb6d3380c51df60201f98ee3f81d45e 409 SUPERFAMILY SSF55120 232 407 1.26E-37 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_0876 bdb6d3380c51df60201f98ee3f81d45e 409 Pfam PF01479 S4 domain 171 216 8.1E-8 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_0876 bdb6d3380c51df60201f98ee3f81d45e 409 Pfam PF00849 RNA pseudouridylate synthase 233 373 8.7E-13 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_1454 837b2c2648f5e0d24bf5c62fa27d7796 822 Pfam PF13567 Domain of unknown function (DUF4131) 28 221 1.0E-29 T 14-10-2018 IPR025405 Domain of unknown function DUF4131 Tharo_1454 837b2c2648f5e0d24bf5c62fa27d7796 822 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 179 792 2.6E-101 T 14-10-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 Tharo_1454 837b2c2648f5e0d24bf5c62fa27d7796 822 Gene3D G3DSA:3.60.15.10 554 809 9.8E-47 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_1454 837b2c2648f5e0d24bf5c62fa27d7796 822 Pfam PF03772 Competence protein 263 524 2.5E-59 T 14-10-2018 IPR004477 ComEC/Rec2-related protein Tharo_1454 837b2c2648f5e0d24bf5c62fa27d7796 822 Pfam PF00753 Metallo-beta-lactamase superfamily 561 723 3.0E-8 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_1454 837b2c2648f5e0d24bf5c62fa27d7796 822 SMART SM00849 562 763 2.9E-8 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_1454 837b2c2648f5e0d24bf5c62fa27d7796 822 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 283 462 1.5E-27 T 14-10-2018 IPR004477 ComEC/Rec2-related protein Tharo_1454 837b2c2648f5e0d24bf5c62fa27d7796 822 SUPERFAMILY SSF56281 553 800 2.17E-40 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_1835 66275494fb41640d771de7c3384e23ca 369 Gene3D G3DSA:3.30.9.10 86 320 1.5E-139 T 14-10-2018 Tharo_1835 66275494fb41640d771de7c3384e23ca 369 SUPERFAMILY SSF51905 4 365 9.71E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1835 66275494fb41640d771de7c3384e23ca 369 Pfam PF01266 FAD dependent oxidoreductase 5 364 3.8E-68 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Tharo_1835 66275494fb41640d771de7c3384e23ca 369 Gene3D G3DSA:3.50.50.60 5 359 1.5E-139 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1693 55a42c434e8ee1704368489ee0ef466d 111 Gene3D G3DSA:2.60.120.10 1 111 9.7E-39 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Tharo_1693 55a42c434e8ee1704368489ee0ef466d 111 SUPERFAMILY SSF51182 15 110 5.03E-31 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily Tharo_1693 55a42c434e8ee1704368489ee0ef466d 111 Hamap MF_01537 Pyrimidine/purine nucleoside phosphorylase [ppnP]. 13 111 27.305 T 14-10-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase KEGG: 00230+2.4.2.15|KEGG: 00240+2.4.2.4+2.4.2.3+2.4.2.2|KEGG: 00983+2.4.2.4+2.4.2.3|MetaCyc: PWY-5532|MetaCyc: PWY-7181 Tharo_1693 55a42c434e8ee1704368489ee0ef466d 111 Pfam PF06865 Protein of unknown function (DUF1255) 15 110 4.3E-35 T 14-10-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase KEGG: 00230+2.4.2.15|KEGG: 00240+2.4.2.4+2.4.2.3+2.4.2.2|KEGG: 00983+2.4.2.4+2.4.2.3|MetaCyc: PWY-5532|MetaCyc: PWY-7181 Tharo_2596 0a5533219dfee998a08c1ff766df4c35 371 ProSitePatterns PS00902 Glutamate 5-kinase signature. 211 228 - T 14-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Tharo_2596 0a5533219dfee998a08c1ff766df4c35 371 TIGRFAM TIGR01027 proB: glutamate 5-kinase 9 369 2.2E-129 T 14-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Tharo_2596 0a5533219dfee998a08c1ff766df4c35 371 Hamap MF_00456 Glutamate 5-kinase [proB]. 9 263 36.058 T 14-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Tharo_2596 0a5533219dfee998a08c1ff766df4c35 371 PRINTS PR00474 Glutamate 5-kinase family signature 80 108 2.6E-50 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Tharo_2596 0a5533219dfee998a08c1ff766df4c35 371 PRINTS PR00474 Glutamate 5-kinase family signature 152 179 2.6E-50 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Tharo_2596 0a5533219dfee998a08c1ff766df4c35 371 PRINTS PR00474 Glutamate 5-kinase family signature 213 233 2.6E-50 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Tharo_2596 0a5533219dfee998a08c1ff766df4c35 371 PRINTS PR00474 Glutamate 5-kinase family signature 46 60 2.6E-50 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Tharo_2596 0a5533219dfee998a08c1ff766df4c35 371 PRINTS PR00474 Glutamate 5-kinase family signature 120 141 2.6E-50 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Tharo_2596 0a5533219dfee998a08c1ff766df4c35 371 Pfam PF00696 Amino acid kinase family 10 237 2.2E-44 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Tharo_2596 0a5533219dfee998a08c1ff766df4c35 371 SUPERFAMILY SSF88697 281 369 2.43E-24 T 14-10-2018 IPR015947 PUA-like superfamily Tharo_2596 0a5533219dfee998a08c1ff766df4c35 371 SUPERFAMILY SSF53633 9 259 1.7E-69 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Tharo_2596 0a5533219dfee998a08c1ff766df4c35 371 Gene3D G3DSA:3.40.1160.10 1 269 3.3E-95 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Tharo_2596 0a5533219dfee998a08c1ff766df4c35 371 Gene3D G3DSA:2.30.130.10 270 370 3.8E-31 T 14-10-2018 IPR036974 PUA domain superfamily GO:0003723 Tharo_2596 0a5533219dfee998a08c1ff766df4c35 371 SMART SM00359 281 363 3.0E-20 T 14-10-2018 IPR002478 PUA domain GO:0003723 Tharo_2596 0a5533219dfee998a08c1ff766df4c35 371 Pfam PF01472 PUA domain 281 353 3.9E-22 T 14-10-2018 IPR002478 PUA domain GO:0003723 Tharo_2596 0a5533219dfee998a08c1ff766df4c35 371 PIRSF PIRSF000729 4 371 1.9E-128 T 14-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 Tharo_1516 5d779f5107adbb32fff190770f74b362 166 Gene3D G3DSA:1.10.10.10 11 160 1.6E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1516 5d779f5107adbb32fff190770f74b362 166 Pfam PF01047 MarR family 53 107 7.6E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_1516 5d779f5107adbb32fff190770f74b362 166 SUPERFAMILY SSF46785 21 155 1.1E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1516 5d779f5107adbb32fff190770f74b362 166 ProSitePatterns PS01117 MarR-type HTH domain signature. 82 116 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site Tharo_1516 5d779f5107adbb32fff190770f74b362 166 SMART SM00347 43 143 4.1E-30 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_1516 5d779f5107adbb32fff190770f74b362 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 103 119 4.7E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_1516 5d779f5107adbb32fff190770f74b362 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 99 4.7E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_1516 5d779f5107adbb32fff190770f74b362 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 133 153 4.7E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_1516 5d779f5107adbb32fff190770f74b362 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 83 4.7E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_2263 179ae8992f89371b98c97cc5e0c862a2 185 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 113 177 3.9E-6 T 14-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_2263 179ae8992f89371b98c97cc5e0c862a2 185 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 124 176 - T 14-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_2263 179ae8992f89371b98c97cc5e0c862a2 185 Gene3D G3DSA:2.60.40.420 76 182 6.3E-27 T 14-10-2018 IPR008972 Cupredoxin Tharo_2263 179ae8992f89371b98c97cc5e0c862a2 185 SUPERFAMILY SSF49503 90 182 7.51E-23 T 14-10-2018 IPR008972 Cupredoxin Tharo_1260 a2d49fae38282e24592e81fd6deb170a 95 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 6 95 2.6E-48 T 14-10-2018 IPR009359 Phenylacetic acid degradation B Tharo_1260 a2d49fae38282e24592e81fd6deb170a 95 PIRSF PIRSF030200 1 95 5.2E-44 T 14-10-2018 IPR009359 Phenylacetic acid degradation B Tharo_1260 a2d49fae38282e24592e81fd6deb170a 95 Pfam PF06243 Phenylacetic acid degradation B 5 92 1.3E-40 T 14-10-2018 IPR009359 Phenylacetic acid degradation B Tharo_1260 a2d49fae38282e24592e81fd6deb170a 95 Gene3D G3DSA:3.10.20.520 1 65 2.6E-32 T 14-10-2018 IPR038693 Phenylacetyl-CoA epoxidase, subunit B Tharo_0822 a1249a988812da2c66b968d44a324906 812 Gene3D G3DSA:2.40.50.140 355 425 1.1E-18 T 14-10-2018 Tharo_0822 a1249a988812da2c66b968d44a324906 812 Gene3D G3DSA:1.10.3810.10 49 245 3.0E-77 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_0822 a1249a988812da2c66b968d44a324906 812 Pfam PF00905 Penicillin binding protein transpeptidase domain 430 677 1.8E-38 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Tharo_0822 a1249a988812da2c66b968d44a324906 812 SUPERFAMILY SSF53955 42 247 1.77E-75 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily Tharo_0822 a1249a988812da2c66b968d44a324906 812 Pfam PF00912 Transglycosylase 55 229 6.5E-65 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_0822 a1249a988812da2c66b968d44a324906 812 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 65 713 1.6E-182 T 14-10-2018 Tharo_0822 a1249a988812da2c66b968d44a324906 812 Pfam PF17092 Penicillin-binding protein OB-like domain 325 427 1.0E-19 T 14-10-2018 IPR031376 Penicillin-binding protein, OB-like domain KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_0822 a1249a988812da2c66b968d44a324906 812 SUPERFAMILY SSF56601 211 740 1.33E-121 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Tharo_2999 a66194fd697384dbd225e1f664a8c005 797 SUPERFAMILY SSF82866 64 393 9.55E-30 T 14-10-2018 Tharo_2999 a66194fd697384dbd225e1f664a8c005 797 Pfam PF03176 MMPL family 584 782 2.9E-12 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 Tharo_2999 a66194fd697384dbd225e1f664a8c005 797 Pfam PF03176 MMPL family 173 420 1.8E-8 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 Tharo_2999 a66194fd697384dbd225e1f664a8c005 797 Gene3D G3DSA:1.20.1640.10 219 409 1.1E-11 T 14-10-2018 Tharo_2999 a66194fd697384dbd225e1f664a8c005 797 Gene3D G3DSA:1.20.1640.10 601 786 2.5E-12 T 14-10-2018 Tharo_2999 a66194fd697384dbd225e1f664a8c005 797 SUPERFAMILY SSF82866 588 781 3.79E-29 T 14-10-2018 Tharo_0577 b80226dda25ff665143d1f9975be1520 76 Gene3D G3DSA:1.20.58.720 1 66 2.6E-8 T 14-10-2018 Tharo_0577 b80226dda25ff665143d1f9975be1520 76 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 3 47 2.2E-15 T 14-10-2018 IPR022453 Zinc finger, MqsA-type Tharo_2622 1fa8159da8827391c88e60655acd38ba 163 SUPERFAMILY SSF52255 5 160 1.83E-68 T 14-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 Tharo_2622 1fa8159da8827391c88e60655acd38ba 163 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 8 161 33.874 T 14-10-2018 IPR033747 Class I PurE Tharo_2622 1fa8159da8827391c88e60655acd38ba 163 PIRSF PIRSF001338 4 162 6.7E-68 T 14-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 Tharo_2622 1fa8159da8827391c88e60655acd38ba 163 SMART SM01001 6 157 2.9E-106 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 Tharo_2622 1fa8159da8827391c88e60655acd38ba 163 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 8 159 2.1E-68 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 Tharo_2622 1fa8159da8827391c88e60655acd38ba 163 Pfam PF00731 AIR carboxylase 8 155 1.4E-66 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 Tharo_2622 1fa8159da8827391c88e60655acd38ba 163 Gene3D G3DSA:3.40.50.7700 1 163 1.5E-75 T 14-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 Tharo_0097 cdab440330814be6e666ebba7385a6b3 210 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 85 96 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_0097 cdab440330814be6e666ebba7385a6b3 210 SUPERFAMILY SSF54862 1 206 1.36E-62 T 14-10-2018 Tharo_0097 cdab440330814be6e666ebba7385a6b3 210 Gene3D G3DSA:3.30.70.20 1 210 5.6E-60 T 14-10-2018 Tharo_0097 cdab440330814be6e666ebba7385a6b3 210 Pfam PF13247 4Fe-4S dicluster domain 47 101 6.3E-12 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_1672 30b499340b9b4b596ab25881d2ced7e4 383 Gene3D G3DSA:2.120.10.30 35 383 1.1E-119 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Tharo_1672 30b499340b9b4b596ab25881d2ced7e4 383 SUPERFAMILY SSF50952 28 382 7.59E-51 T 14-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 Tharo_1672 30b499340b9b4b596ab25881d2ced7e4 383 Pfam PF07995 Glucose / Sorbosone dehydrogenase 50 379 4.7E-136 T 14-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase Tharo_1477 cc660d79822379c57eb442aee116ddca 330 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 161 325 6.2E-31 T 14-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 Tharo_1477 cc660d79822379c57eb442aee116ddca 330 SUPERFAMILY SSF51735 4 159 4.36E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1477 cc660d79822379c57eb442aee116ddca 330 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 329 54.653 T 14-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 Tharo_1477 cc660d79822379c57eb442aee116ddca 330 PIRSF PIRSF000102 2 328 1.4E-57 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 Tharo_1477 cc660d79822379c57eb442aee116ddca 330 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 4 324 1.1E-139 T 14-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 Tharo_1477 cc660d79822379c57eb442aee116ddca 330 SUPERFAMILY SSF56327 161 329 6.64E-57 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 Tharo_1477 cc660d79822379c57eb442aee116ddca 330 Gene3D G3DSA:3.90.110.10 159 330 1.7E-58 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 Tharo_1477 cc660d79822379c57eb442aee116ddca 330 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 6 146 1.6E-37 T 14-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 Tharo_1477 cc660d79822379c57eb442aee116ddca 330 Gene3D G3DSA:3.40.50.720 1 158 1.2E-58 T 14-10-2018 Tharo_0898 391630d7ddd0f778f31571419b0d1035 295 SUPERFAMILY SSF69593 36 266 1.14E-25 T 14-10-2018 Tharo_0898 391630d7ddd0f778f31571419b0d1035 295 Pfam PF01553 Acyltransferase 90 200 1.2E-19 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Tharo_0898 391630d7ddd0f778f31571419b0d1035 295 SMART SM00563 92 204 1.1E-26 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Tharo_0149 41ee078ff43c42b98548dbbde531aaad 153 SUPERFAMILY SSF46626 65 140 1.39E-17 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_0149 41ee078ff43c42b98548dbbde531aaad 153 PRINTS PR00607 Class IE cytochrome C signature 113 125 2.7E-14 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 Tharo_0149 41ee078ff43c42b98548dbbde531aaad 153 PRINTS PR00607 Class IE cytochrome C signature 128 139 2.7E-14 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 Tharo_0149 41ee078ff43c42b98548dbbde531aaad 153 PRINTS PR00607 Class IE cytochrome C signature 85 95 2.7E-14 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 Tharo_0149 41ee078ff43c42b98548dbbde531aaad 153 PRINTS PR00607 Class IE cytochrome C signature 74 85 2.7E-14 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 Tharo_0149 41ee078ff43c42b98548dbbde531aaad 153 Gene3D G3DSA:1.10.760.10 63 141 3.8E-30 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_0149 41ee078ff43c42b98548dbbde531aaad 153 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 65 138 4.0E-17 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 Gene3D G3DSA:3.30.70.1430 42 812 2.5E-270 T 14-10-2018 Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 Gene3D G3DSA:1.20.1640.10 14 511 2.5E-270 T 14-10-2018 Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 Gene3D G3DSA:3.30.70.1440 668 862 2.5E-270 T 14-10-2018 Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1028 4.7E-246 T 14-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 Gene3D G3DSA:1.20.1640.10 512 1020 2.5E-270 T 14-10-2018 Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 Pfam PF00873 AcrB/AcrD/AcrF family 9 1022 1.4E-255 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 Gene3D G3DSA:3.30.2090.10 182 273 2.5E-270 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 1.0E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 PRINTS PR00702 Acriflavin resistance protein family signature 388 412 1.0E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 1.0E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 1.0E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 PRINTS PR00702 Acriflavin resistance protein family signature 360 381 1.0E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 1.0E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 PRINTS PR00702 Acriflavin resistance protein family signature 549 566 1.0E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 SUPERFAMILY SSF82714 717 800 2.75E-13 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 Gene3D G3DSA:3.30.70.1320 135 327 2.5E-270 T 14-10-2018 Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 SUPERFAMILY SSF82714 185 266 6.15E-14 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 SUPERFAMILY SSF82693 139 319 7.67E-19 T 14-10-2018 Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 SUPERFAMILY SSF82693 43 127 7.06E-21 T 14-10-2018 Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 SUPERFAMILY SSF82866 294 501 1.83E-36 T 14-10-2018 Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 Gene3D G3DSA:3.30.2090.10 718 804 2.5E-270 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 SUPERFAMILY SSF82866 798 1026 6.67E-48 T 14-10-2018 Tharo_1859 f4400e1d58f9a08bdd40d9dbdffed7b3 1039 Gene3D G3DSA:3.30.70.1430 566 666 2.5E-270 T 14-10-2018 Tharo_3078 021626f3e8608944f1d624f43aee56db 314 Gene3D G3DSA:3.40.50.720 1 310 1.0E-39 T 14-10-2018 Tharo_3078 021626f3e8608944f1d624f43aee56db 314 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 223 2.2E-13 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 Tharo_3078 021626f3e8608944f1d624f43aee56db 314 SUPERFAMILY SSF51735 3 301 1.65E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1615 afdba78a5aa4827e12008551a75bb0a5 262 Gene3D G3DSA:2.10.109.10 56 252 6.5E-75 T 14-10-2018 Tharo_1615 afdba78a5aa4827e12008551a75bb0a5 262 ProSitePatterns PS00760 Signal peptidases I lysine active site. 124 136 - T 14-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 Tharo_1615 afdba78a5aa4827e12008551a75bb0a5 262 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 58 74 4.8E-25 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Tharo_1615 afdba78a5aa4827e12008551a75bb0a5 262 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 122 134 4.8E-25 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Tharo_1615 afdba78a5aa4827e12008551a75bb0a5 262 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 212 231 4.8E-25 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Tharo_1615 afdba78a5aa4827e12008551a75bb0a5 262 ProSitePatterns PS00501 Signal peptidases I serine active site. 67 74 - T 14-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 Tharo_1615 afdba78a5aa4827e12008551a75bb0a5 262 SUPERFAMILY SSF51306 56 258 1.94E-70 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily Tharo_1615 afdba78a5aa4827e12008551a75bb0a5 262 Pfam PF10502 Signal peptidase, peptidase S26 210 249 3.0E-5 T 14-10-2018 IPR019533 Peptidase S26 Tharo_1615 afdba78a5aa4827e12008551a75bb0a5 262 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 44 252 1.7E-48 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Tharo_1615 afdba78a5aa4827e12008551a75bb0a5 262 ProSitePatterns PS00761 Signal peptidases I signature 3. 217 230 - T 14-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 Tharo_1615 afdba78a5aa4827e12008551a75bb0a5 262 Gene3D G3DSA:2.170.230.10 133 211 6.5E-75 T 14-10-2018 Tharo_1615 afdba78a5aa4827e12008551a75bb0a5 262 Pfam PF00717 Peptidase S24-like 64 146 3.2E-20 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C Tharo_0547 e2aa91b1fd08be69c1eb20e3385ff738 179 SUPERFAMILY SSF52172 8 165 3.13E-28 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_0547 e2aa91b1fd08be69c1eb20e3385ff738 179 Pfam PF02954 Bacterial regulatory protein, Fis family 136 175 6.4E-11 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_0547 e2aa91b1fd08be69c1eb20e3385ff738 179 Pfam PF00072 Response regulator receiver domain 10 118 1.8E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_0547 e2aa91b1fd08be69c1eb20e3385ff738 179 Gene3D G3DSA:3.40.50.2300 8 122 7.0E-26 T 14-10-2018 Tharo_0547 e2aa91b1fd08be69c1eb20e3385ff738 179 SMART SM00448 7 118 2.6E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_0547 e2aa91b1fd08be69c1eb20e3385ff738 179 Gene3D G3DSA:1.10.10.60 123 178 1.0E-22 T 14-10-2018 Tharo_2284 40334d5411b21a9b22c61be0bc68c47e 389 Gene3D G3DSA:3.20.20.70 26 358 7.6E-33 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_2284 40334d5411b21a9b22c61be0bc68c47e 389 SUPERFAMILY SSF102114 27 322 3.14E-35 T 14-10-2018 Tharo_2284 40334d5411b21a9b22c61be0bc68c47e 389 Pfam PF04055 Radical SAM superfamily 32 185 5.0E-12 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_2284 40334d5411b21a9b22c61be0bc68c47e 389 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 259 327 6.2E-10 T 14-10-2018 IPR023885 4Fe4S-binding SPASM domain Tharo_2284 40334d5411b21a9b22c61be0bc68c47e 389 Pfam PF13353 4Fe-4S single cluster domain 32 133 7.9E-5 T 14-10-2018 Tharo_2462 1528e456379d49a413fb63e041c46dc4 811 Pfam PF01636 Phosphotransferase enzyme family 511 726 4.1E-16 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase Tharo_2462 1528e456379d49a413fb63e041c46dc4 811 SUPERFAMILY SSF56112 494 778 7.91E-33 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Tharo_2462 1528e456379d49a413fb63e041c46dc4 811 Gene3D G3DSA:3.90.1200.10 596 794 2.5E-12 T 14-10-2018 Tharo_3285 7ca99a932d3a9f381f158bb0173ecc67 505 SUPERFAMILY SSF53720 19 485 1.44E-127 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Tharo_3285 7ca99a932d3a9f381f158bb0173ecc67 505 Gene3D G3DSA:3.40.605.10 24 475 4.5E-134 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Tharo_3285 7ca99a932d3a9f381f158bb0173ecc67 505 Gene3D G3DSA:3.40.309.10 256 450 4.5E-134 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Tharo_3285 7ca99a932d3a9f381f158bb0173ecc67 505 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 Tharo_3285 7ca99a932d3a9f381f158bb0173ecc67 505 Pfam PF00171 Aldehyde dehydrogenase family 22 478 1.8E-120 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Tharo_3280 2bef84d9c1bf4201d878d9e425a1380f 434 Gene3D G3DSA:3.30.420.350 132 413 8.4E-92 T 14-10-2018 Tharo_3280 2bef84d9c1bf4201d878d9e425a1380f 434 Gene3D G3DSA:3.30.420.360 41 425 8.4E-92 T 14-10-2018 Tharo_3280 2bef84d9c1bf4201d878d9e425a1380f 434 SUPERFAMILY SSF53067 322 428 1.71E-5 T 14-10-2018 Tharo_2818 55de7762c8731c706a2f944d5a890e8b 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 341 1.7E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2818 55de7762c8731c706a2f944d5a890e8b 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 402 1.7E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2818 55de7762c8731c706a2f944d5a890e8b 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 383 1.7E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2818 55de7762c8731c706a2f944d5a890e8b 410 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 257 403 6.3E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2818 55de7762c8731c706a2f944d5a890e8b 410 SUPERFAMILY SSF47384 135 207 7.46E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_2818 55de7762c8731c706a2f944d5a890e8b 410 Pfam PF13493 Domain of unknown function (DUF4118) 19 124 1.8E-27 T 14-10-2018 IPR025201 Sensor protein KdpD, transmembrane domain Tharo_2818 55de7762c8731c706a2f944d5a890e8b 410 Gene3D G3DSA:1.20.120.620 15 118 7.2E-32 T 14-10-2018 IPR038318 KdpD, transmembrane domain superfamily Tharo_2818 55de7762c8731c706a2f944d5a890e8b 410 Gene3D G3DSA:1.10.287.130 127 209 7.4E-14 T 14-10-2018 Tharo_2818 55de7762c8731c706a2f944d5a890e8b 410 SUPERFAMILY SSF55874 198 405 1.45E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2818 55de7762c8731c706a2f944d5a890e8b 410 Pfam PF00512 His Kinase A (phospho-acceptor) domain 142 207 1.2E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_2818 55de7762c8731c706a2f944d5a890e8b 410 SMART SM00388 141 208 2.6E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_2818 55de7762c8731c706a2f944d5a890e8b 410 SMART SM00387 252 405 1.9E-33 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2818 55de7762c8731c706a2f944d5a890e8b 410 Gene3D G3DSA:3.30.565.10 215 407 1.4E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2684 1ecdc21f57f64ae3f17abb7f0cc62143 298 Gene3D G3DSA:2.60.120.10 158 266 5.7E-96 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Tharo_2684 1ecdc21f57f64ae3f17abb7f0cc62143 298 Pfam PF05726 Pirin C-terminal cupin domain 191 296 3.6E-30 T 14-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 Tharo_2684 1ecdc21f57f64ae3f17abb7f0cc62143 298 Gene3D G3DSA:2.60.120.10 31 292 5.7E-96 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Tharo_2684 1ecdc21f57f64ae3f17abb7f0cc62143 298 Pfam PF02678 Pirin 35 136 6.0E-35 T 14-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 Tharo_2684 1ecdc21f57f64ae3f17abb7f0cc62143 298 PIRSF PIRSF006232 16 298 6.7E-98 T 14-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 Tharo_2684 1ecdc21f57f64ae3f17abb7f0cc62143 298 SUPERFAMILY SSF51182 18 297 1.57E-84 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily Tharo_1207 6897a3f4f578c50c600959a909bbc3b8 355 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 238 260 - T 14-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 Tharo_1207 6897a3f4f578c50c600959a909bbc3b8 355 Gene3D G3DSA:3.40.190.10 90 260 5.0E-58 T 14-10-2018 Tharo_1207 6897a3f4f578c50c600959a909bbc3b8 355 SUPERFAMILY SSF48600 3 90 6.96E-21 T 14-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Tharo_1207 6897a3f4f578c50c600959a909bbc3b8 355 Pfam PF00800 Prephenate dehydratase 88 263 1.7E-60 T 14-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 Tharo_1207 6897a3f4f578c50c600959a909bbc3b8 355 PIRSF PIRSF001500 1 355 1.6E-135 T 14-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 Tharo_1207 6897a3f4f578c50c600959a909bbc3b8 355 Gene3D G3DSA:3.30.70.260 266 354 3.9E-29 T 14-10-2018 Tharo_1207 6897a3f4f578c50c600959a909bbc3b8 355 Gene3D G3DSA:1.20.59.10 1 85 5.4E-27 T 14-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Tharo_1207 6897a3f4f578c50c600959a909bbc3b8 355 Pfam PF01817 Chorismate mutase type II 9 84 5.6E-23 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Tharo_1207 6897a3f4f578c50c600959a909bbc3b8 355 SUPERFAMILY SSF53850 87 270 1.63E-57 T 14-10-2018 Tharo_1207 6897a3f4f578c50c600959a909bbc3b8 355 Gene3D G3DSA:3.40.190.10 168 252 5.0E-58 T 14-10-2018 Tharo_1207 6897a3f4f578c50c600959a909bbc3b8 355 TIGRFAM TIGR01807 CM_P2: chorismate mutase 5 76 3.3E-26 T 14-10-2018 IPR010957 Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 Tharo_1207 6897a3f4f578c50c600959a909bbc3b8 355 Pfam PF01842 ACT domain 273 337 3.1E-9 T 14-10-2018 IPR002912 ACT domain Tharo_1207 6897a3f4f578c50c600959a909bbc3b8 355 SMART SM00830 9 86 8.2E-29 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Tharo_1207 6897a3f4f578c50c600959a909bbc3b8 355 SUPERFAMILY SSF55021 257 351 2.36E-27 T 14-10-2018 Tharo_0452 d86500acb4296ab31864f09973383cfe 518 Gene3D G3DSA:3.40.50.300 6 237 2.4E-54 T 14-10-2018 Tharo_0452 d86500acb4296ab31864f09973383cfe 518 SUPERFAMILY SSF52317 256 464 8.28E-35 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Tharo_0452 d86500acb4296ab31864f09973383cfe 518 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 511 204.965 T 14-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 Tharo_0452 d86500acb4296ab31864f09973383cfe 518 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 7 503 8.3E-137 T 14-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 Tharo_0452 d86500acb4296ab31864f09973383cfe 518 SUPERFAMILY SSF52540 6 240 9.97E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0452 d86500acb4296ab31864f09973383cfe 518 Gene3D G3DSA:3.40.50.880 262 445 1.5E-15 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Tharo_0452 d86500acb4296ab31864f09973383cfe 518 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 232 2.2E-22 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain Tharo_0452 d86500acb4296ab31864f09973383cfe 518 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 256 453 9.5E-56 T 14-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 Tharo_1255 c6bc83e6245e9c9c15923ddc52f84edc 554 Gene3D G3DSA:3.40.309.10 312 523 6.4E-18 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Tharo_1255 c6bc83e6245e9c9c15923ddc52f84edc 554 Pfam PF00171 Aldehyde dehydrogenase family 90 499 3.8E-38 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Tharo_1255 c6bc83e6245e9c9c15923ddc52f84edc 554 TIGRFAM TIGR02288 PaaN_2: phenylacetic acid degradation protein paaN 3 552 2.9E-283 T 14-10-2018 IPR011975 Phenylacetic acid degradation protein PaaN2 Tharo_1255 c6bc83e6245e9c9c15923ddc52f84edc 554 SUPERFAMILY SSF53720 81 539 1.22E-63 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Tharo_1255 c6bc83e6245e9c9c15923ddc52f84edc 554 Gene3D G3DSA:3.40.605.10 84 308 9.5E-32 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Tharo_0981 b7e758eb24726f020ae4884fc0268d2b 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 184 2.8E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_0981 b7e758eb24726f020ae4884fc0268d2b 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 156 2.8E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_0981 b7e758eb24726f020ae4884fc0268d2b 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 172 2.8E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_0981 b7e758eb24726f020ae4884fc0268d2b 201 Gene3D G3DSA:3.40.50.2300 1 130 1.2E-43 T 14-10-2018 Tharo_0981 b7e758eb24726f020ae4884fc0268d2b 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 194 2.0E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_0981 b7e758eb24726f020ae4884fc0268d2b 201 SMART SM00421 139 196 4.4E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_0981 b7e758eb24726f020ae4884fc0268d2b 201 Gene3D G3DSA:1.10.10.10 133 197 4.1E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0981 b7e758eb24726f020ae4884fc0268d2b 201 Pfam PF00072 Response regulator receiver domain 8 115 1.6E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_0981 b7e758eb24726f020ae4884fc0268d2b 201 ProSitePatterns PS00622 LuxR-type HTH domain signature. 156 183 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_0981 b7e758eb24726f020ae4884fc0268d2b 201 SMART SM00448 4 115 5.1E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_0981 b7e758eb24726f020ae4884fc0268d2b 201 SUPERFAMILY SSF46894 132 195 1.6E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_0981 b7e758eb24726f020ae4884fc0268d2b 201 SUPERFAMILY SSF52172 8 149 1.04E-29 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_3418 ccc768ba84017e939d24fbb72538b720 57 TIGRFAM TIGR04359 TrbK_RP4: entry exclusion lipoprotein TrbK 6 55 1.9E-11 T 14-10-2018 IPR027584 Entry exclusion lipoprotein TrbK Tharo_1794 cc3a30eae60d5a871deef088ae161821 183 Pfam PF13649 Methyltransferase domain 29 113 1.4E-8 T 14-10-2018 Tharo_1794 cc3a30eae60d5a871deef088ae161821 183 SUPERFAMILY SSF53335 12 170 3.75E-26 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_1794 cc3a30eae60d5a871deef088ae161821 183 Gene3D G3DSA:3.40.50.150 3 175 1.6E-26 T 14-10-2018 Tharo_2904 6ef997595d0be2a811de237bc66dceb9 460 Gene3D G3DSA:1.10.10.60 403 454 2.5E-10 T 14-10-2018 Tharo_2904 6ef997595d0be2a811de237bc66dceb9 460 Pfam PF02954 Bacterial regulatory protein, Fis family 414 452 4.2E-6 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_2904 6ef997595d0be2a811de237bc66dceb9 460 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 361 370 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Tharo_2904 6ef997595d0be2a811de237bc66dceb9 460 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 171 184 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Tharo_2904 6ef997595d0be2a811de237bc66dceb9 460 SMART SM00448 5 116 8.0E-36 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2904 6ef997595d0be2a811de237bc66dceb9 460 Gene3D G3DSA:1.10.8.60 318 396 2.9E-24 T 14-10-2018 Tharo_2904 6ef997595d0be2a811de237bc66dceb9 460 SUPERFAMILY SSF52540 146 386 2.24E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2904 6ef997595d0be2a811de237bc66dceb9 460 Gene3D G3DSA:3.40.50.2300 1 137 1.3E-39 T 14-10-2018 Tharo_2904 6ef997595d0be2a811de237bc66dceb9 460 Pfam PF00072 Response regulator receiver domain 7 114 6.4E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2904 6ef997595d0be2a811de237bc66dceb9 460 SUPERFAMILY SSF46689 361 452 2.29E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_2904 6ef997595d0be2a811de237bc66dceb9 460 Gene3D G3DSA:3.40.50.300 138 317 3.1E-59 T 14-10-2018 Tharo_2904 6ef997595d0be2a811de237bc66dceb9 460 SMART SM00382 167 310 7.6E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2904 6ef997595d0be2a811de237bc66dceb9 460 Pfam PF00158 Sigma-54 interaction domain 147 314 1.3E-62 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Tharo_2904 6ef997595d0be2a811de237bc66dceb9 460 SUPERFAMILY SSF52172 3 192 1.42E-48 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1442 c7cdcdf4809dd6d39824b8ddb98af6ed 399 Gene3D G3DSA:3.30.70.2050 245 300 1.2E-6 T 14-10-2018 Tharo_1442 c7cdcdf4809dd6d39824b8ddb98af6ed 399 SUPERFAMILY SSF160387 246 283 7.06E-11 T 14-10-2018 Tharo_1442 c7cdcdf4809dd6d39824b8ddb98af6ed 399 Pfam PF12679 ABC-2 family transporter protein 8 223 1.0E-36 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 Tharo_1442 c7cdcdf4809dd6d39824b8ddb98af6ed 399 Pfam PF05573 NosL 246 283 1.7E-11 T 14-10-2018 IPR008719 Nitrous oxide reductase accessory protein NosL Tharo_1710 a3bf9d6468203a368df00d05f0ddd721 654 SUPERFAMILY SSF56801 10 651 3.01E-177 T 14-10-2018 Tharo_1710 a3bf9d6468203a368df00d05f0ddd721 654 ProSitePatterns PS00455 Putative AMP-binding domain signature. 263 274 - T 14-10-2018 IPR020845 AMP-binding, conserved site Tharo_1710 a3bf9d6468203a368df00d05f0ddd721 654 Pfam PF00501 AMP-binding enzyme 91 531 1.1E-95 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Tharo_1710 a3bf9d6468203a368df00d05f0ddd721 654 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 5 654 51.317 T 14-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 Tharo_1710 a3bf9d6468203a368df00d05f0ddd721 654 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 24 653 2.4E-293 T 14-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 Tharo_1710 a3bf9d6468203a368df00d05f0ddd721 654 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 28 83 2.1E-22 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 Tharo_1710 a3bf9d6468203a368df00d05f0ddd721 654 Pfam PF13193 AMP-binding enzyme C-terminal domain 540 621 1.0E-26 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Tharo_1710 a3bf9d6468203a368df00d05f0ddd721 654 Gene3D G3DSA:3.30.300.30 527 654 1.2E-28 T 14-10-2018 Tharo_1710 a3bf9d6468203a368df00d05f0ddd721 654 Gene3D G3DSA:3.40.50.12780 54 524 8.8E-105 T 14-10-2018 Tharo_2628 fb1cd33e4c48b2c518b9e134011b6df8 893 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 85 303 1.2E-9 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Tharo_2628 fb1cd33e4c48b2c518b9e134011b6df8 893 PIRSF PIRSF000156 3 893 0.0 T 14-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 Tharo_2628 fb1cd33e4c48b2c518b9e134011b6df8 893 Gene3D G3DSA:3.40.50.970 476 710 7.3E-108 T 14-10-2018 Tharo_2628 fb1cd33e4c48b2c518b9e134011b6df8 893 Gene3D G3DSA:3.40.50.970 60 475 1.5E-126 T 14-10-2018 Tharo_2628 fb1cd33e4c48b2c518b9e134011b6df8 893 SUPERFAMILY SSF52518 61 471 1.2E-131 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_2628 fb1cd33e4c48b2c518b9e134011b6df8 893 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 11 892 0.0 T 14-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 Tharo_2628 fb1cd33e4c48b2c518b9e134011b6df8 893 Gene3D G3DSA:3.40.50.920 711 893 8.9E-70 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Tharo_2628 fb1cd33e4c48b2c518b9e134011b6df8 893 SUPERFAMILY SSF52922 706 891 6.28E-56 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Tharo_2628 fb1cd33e4c48b2c518b9e134011b6df8 893 SUPERFAMILY SSF52518 477 704 2.35E-95 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_1208 43428a3794333fb83b09b8a0fef57857 365 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 6 364 61.553 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 Tharo_1208 43428a3794333fb83b09b8a0fef57857 365 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 225 234 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 Tharo_1208 43428a3794333fb83b09b8a0fef57857 365 SUPERFAMILY SSF53383 15 364 2.48E-85 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_1208 43428a3794333fb83b09b8a0fef57857 365 Pfam PF00155 Aminotransferase class I and II 36 359 3.3E-52 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Tharo_1208 43428a3794333fb83b09b8a0fef57857 365 Gene3D G3DSA:3.40.640.10 49 273 3.5E-113 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_1208 43428a3794333fb83b09b8a0fef57857 365 Gene3D G3DSA:3.90.1150.10 25 358 3.5E-113 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_1208 43428a3794333fb83b09b8a0fef57857 365 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 10 362 2.8E-107 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 Tharo_1007 9f0b030b152c3d9a31046daa0c4bbe9f 246 SUPERFAMILY SSF55469 22 226 1.57E-53 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Tharo_1007 9f0b030b152c3d9a31046daa0c4bbe9f 246 Gene3D G3DSA:3.40.109.10 1 199 5.0E-57 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Tharo_1007 9f0b030b152c3d9a31046daa0c4bbe9f 246 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 14 213 1.1E-82 T 14-10-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5523 Tharo_1007 9f0b030b152c3d9a31046daa0c4bbe9f 246 Pfam PF00881 Nitroreductase family 26 193 3.4E-30 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 Tharo_0232 6905b0a9439270833cbc732309e24187 427 SUPERFAMILY SSF52540 266 425 1.3E-5 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0299 7b74c3e806f67fa8805c2cd1884f3c24 292 SUPERFAMILY SSF46785 1 86 9.85E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0299 7b74c3e806f67fa8805c2cd1884f3c24 292 Gene3D G3DSA:3.40.190.10 93 286 3.1E-31 T 14-10-2018 Tharo_0299 7b74c3e806f67fa8805c2cd1884f3c24 292 Gene3D G3DSA:1.10.10.10 1 85 1.7E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0299 7b74c3e806f67fa8805c2cd1884f3c24 292 Pfam PF03466 LysR substrate binding domain 88 289 1.1E-31 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_0299 7b74c3e806f67fa8805c2cd1884f3c24 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0299 7b74c3e806f67fa8805c2cd1884f3c24 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0299 7b74c3e806f67fa8805c2cd1884f3c24 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0299 7b74c3e806f67fa8805c2cd1884f3c24 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.0E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0299 7b74c3e806f67fa8805c2cd1884f3c24 292 SUPERFAMILY SSF53850 91 289 5.27E-29 T 14-10-2018 Tharo_0299 7b74c3e806f67fa8805c2cd1884f3c24 292 Gene3D G3DSA:3.40.190.10 163 268 3.1E-31 T 14-10-2018 Tharo_0393 f8b99037c1d8dd15b003b9e4b52bb6ef 105 Hamap MF_00725 Flagellar transcriptional regulator FlhD [flhD]. 1 104 20.043 T 14-10-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 Tharo_0393 f8b99037c1d8dd15b003b9e4b52bb6ef 105 Gene3D G3DSA:1.10.4000.10 1 105 6.9E-33 T 14-10-2018 IPR036194 Flagellar transcriptional activator FlhD superfamily Tharo_0393 f8b99037c1d8dd15b003b9e4b52bb6ef 105 Pfam PF05247 Flagellar transcriptional activator (FlhD) 1 99 3.7E-31 T 14-10-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 Tharo_0393 f8b99037c1d8dd15b003b9e4b52bb6ef 105 ProDom PD015582 ACTIVATOR TRANSCRIPTIONAL TRANSCRIPTION FLAGELLUM FLHD FLAGELLAR DNA-BINDING REGULATION REGULATOR PROBABLE 10 98 5.0E-21 T 14-10-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 Tharo_0393 f8b99037c1d8dd15b003b9e4b52bb6ef 105 SUPERFAMILY SSF63592 1 98 1.83E-26 T 14-10-2018 IPR036194 Flagellar transcriptional activator FlhD superfamily Tharo_0156 018916b3cdbb19f4be02f5188e51e513 316 Pfam PF00665 Integrase core domain 124 237 1.2E-28 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Tharo_0156 018916b3cdbb19f4be02f5188e51e513 316 Gene3D G3DSA:3.30.420.10 121 285 7.9E-13 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_0156 018916b3cdbb19f4be02f5188e51e513 316 SUPERFAMILY SSF53098 117 283 8.8E-39 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_0156 018916b3cdbb19f4be02f5188e51e513 316 Pfam PF13276 HTH-like domain 49 99 1.7E-13 T 14-10-2018 IPR025948 HTH-like domain Tharo_2233 018916b3cdbb19f4be02f5188e51e513 316 Pfam PF00665 Integrase core domain 124 237 1.2E-28 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Tharo_2233 018916b3cdbb19f4be02f5188e51e513 316 Gene3D G3DSA:3.30.420.10 121 285 7.9E-13 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_2233 018916b3cdbb19f4be02f5188e51e513 316 SUPERFAMILY SSF53098 117 283 8.8E-39 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_2233 018916b3cdbb19f4be02f5188e51e513 316 Pfam PF13276 HTH-like domain 49 99 1.7E-13 T 14-10-2018 IPR025948 HTH-like domain Tharo_0230 018916b3cdbb19f4be02f5188e51e513 316 Pfam PF00665 Integrase core domain 124 237 1.2E-28 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Tharo_0230 018916b3cdbb19f4be02f5188e51e513 316 Gene3D G3DSA:3.30.420.10 121 285 7.9E-13 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_0230 018916b3cdbb19f4be02f5188e51e513 316 SUPERFAMILY SSF53098 117 283 8.8E-39 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_0230 018916b3cdbb19f4be02f5188e51e513 316 Pfam PF13276 HTH-like domain 49 99 1.7E-13 T 14-10-2018 IPR025948 HTH-like domain Tharo_1392 82f15179e2f8feebd544e606430bbbe6 612 Pfam PF02705 K+ potassium transporter 3 534 5.0E-210 T 14-10-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 Tharo_1392 82f15179e2f8feebd544e606430bbbe6 612 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 1 612 34.23 T 14-10-2018 IPR023051 Potassium uptake protein, low affinity, Kup Tharo_1099 c4e363fa7535b28e4facc1ef1827268b 341 SUPERFAMILY SSF51556 1 335 4.4E-96 T 14-10-2018 IPR032466 Metal-dependent hydrolase Tharo_1099 c4e363fa7535b28e4facc1ef1827268b 341 Pfam PF04909 Amidohydrolase 3 330 1.5E-59 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Tharo_1099 c4e363fa7535b28e4facc1ef1827268b 341 Gene3D G3DSA:3.20.20.140 1 341 3.5E-97 T 14-10-2018 Tharo_0678 1c397708f5d27f5b207a8e4c60e0904a 359 SUPERFAMILY SSF111369 175 298 3.66E-7 T 14-10-2018 Tharo_0678 1c397708f5d27f5b207a8e4c60e0904a 359 Gene3D G3DSA:2.40.30.170 230 328 3.2E-12 T 14-10-2018 Tharo_0678 1c397708f5d27f5b207a8e4c60e0904a 359 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 50 302 4.2E-15 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Tharo_0678 1c397708f5d27f5b207a8e4c60e0904a 359 Gene3D G3DSA:1.10.287.470 112 195 2.8E-9 T 14-10-2018 Tharo_0678 1c397708f5d27f5b207a8e4c60e0904a 359 Gene3D G3DSA:1.10.287.470 85 111 2.9E-7 T 14-10-2018 Tharo_0678 1c397708f5d27f5b207a8e4c60e0904a 359 Gene3D G3DSA:2.40.50.100 51 84 2.9E-7 T 14-10-2018 Tharo_0678 1c397708f5d27f5b207a8e4c60e0904a 359 SUPERFAMILY SSF111369 44 123 5.62E-7 T 14-10-2018 Tharo_0678 1c397708f5d27f5b207a8e4c60e0904a 359 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 331 346 6.9E-6 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_0678 1c397708f5d27f5b207a8e4c60e0904a 359 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 62 82 6.9E-6 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_3024 084d0432d45038da65c17e2e26c7bb6f 63 Pfam PF09827 CRISPR associated protein Cas2 1 45 1.0E-10 T 14-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 Tharo_3024 084d0432d45038da65c17e2e26c7bb6f 63 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 57 2.8E-6 T 14-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 Tharo_3024 084d0432d45038da65c17e2e26c7bb6f 63 Gene3D G3DSA:3.30.70.240 1 63 1.8E-18 T 14-10-2018 Tharo_3024 084d0432d45038da65c17e2e26c7bb6f 63 PIRSF PIRSF032582 1 63 4.8E-21 T 14-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 Tharo_3024 084d0432d45038da65c17e2e26c7bb6f 63 SUPERFAMILY SSF143430 1 55 5.89E-15 T 14-10-2018 Tharo_2266 15c6cf693b42cd520f20c074c70b3644 380 Gene3D G3DSA:3.40.50.180 182 379 7.8E-74 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal Tharo_2266 15c6cf693b42cd520f20c074c70b3644 380 SUPERFAMILY SSF52172 11 117 3.98E-30 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_2266 15c6cf693b42cd520f20c074c70b3644 380 Pfam PF01339 CheB methylesterase 193 371 6.6E-59 T 14-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Tharo_2266 15c6cf693b42cd520f20c074c70b3644 380 Gene3D G3DSA:3.40.50.2300 11 150 1.0E-32 T 14-10-2018 Tharo_2266 15c6cf693b42cd520f20c074c70b3644 380 Pfam PF00072 Response regulator receiver domain 15 118 4.8E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2266 15c6cf693b42cd520f20c074c70b3644 380 PIRSF PIRSF000876 10 379 2.8E-132 T 14-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Tharo_2266 15c6cf693b42cd520f20c074c70b3644 380 SUPERFAMILY SSF52738 189 376 7.19E-70 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal Tharo_2266 15c6cf693b42cd520f20c074c70b3644 380 SMART SM00448 13 136 2.8E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2266 15c6cf693b42cd520f20c074c70b3644 380 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 13 376 40.007 T 14-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Tharo_2700 2d36b61c45dd286d63e275e0c0e71d71 209 Gene3D G3DSA:1.10.1050.10 6 209 6.2E-83 T 14-10-2018 Tharo_2700 2d36b61c45dd286d63e275e0c0e71d71 209 SMART SM01390 3 98 1.9E-52 T 14-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 Tharo_2700 2d36b61c45dd286d63e275e0c0e71d71 209 SMART SM00363 99 157 4.3E-17 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2700 2d36b61c45dd286d63e275e0c0e71d71 209 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 4 209 2.8E-71 T 14-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 Tharo_2700 2d36b61c45dd286d63e275e0c0e71d71 209 Gene3D G3DSA:3.10.290.10 98 194 6.2E-83 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Tharo_2700 2d36b61c45dd286d63e275e0c0e71d71 209 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 98 1.2E-31 T 14-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 Tharo_2700 2d36b61c45dd286d63e275e0c0e71d71 209 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 209 34.675 T 14-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 Tharo_2700 2d36b61c45dd286d63e275e0c0e71d71 209 SUPERFAMILY SSF55174 2 209 1.7E-66 T 14-10-2018 Tharo_2700 2d36b61c45dd286d63e275e0c0e71d71 209 Pfam PF01479 S4 domain 100 146 9.1E-18 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_0106 a866ebe2c25d5dae13d80bc9ba8a8215 218 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 20 213 25.198 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Tharo_0106 a866ebe2c25d5dae13d80bc9ba8a8215 218 SUPERFAMILY SSF53335 12 216 2.47E-30 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_0106 a866ebe2c25d5dae13d80bc9ba8a8215 218 Gene3D G3DSA:3.40.50.150 5 218 1.3E-61 T 14-10-2018 Tharo_0106 a866ebe2c25d5dae13d80bc9ba8a8215 218 Pfam PF02527 rRNA small subunit methyltransferase G 31 211 4.7E-46 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Tharo_0106 a866ebe2c25d5dae13d80bc9ba8a8215 218 PIRSF PIRSF003078 8 218 7.0E-49 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Tharo_0106 a866ebe2c25d5dae13d80bc9ba8a8215 218 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 32 215 4.5E-46 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Tharo_2804 4a999bbe27a1df3e173b6c79cff90824 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 196 2.2E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2804 4a999bbe27a1df3e173b6c79cff90824 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 2.4E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2804 4a999bbe27a1df3e173b6c79cff90824 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 2.4E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2804 4a999bbe27a1df3e173b6c79cff90824 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 2.4E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2804 4a999bbe27a1df3e173b6c79cff90824 209 SUPERFAMILY SSF46894 142 199 1.8E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_2804 4a999bbe27a1df3e173b6c79cff90824 209 SMART SM00421 142 199 1.4E-23 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2804 4a999bbe27a1df3e173b6c79cff90824 209 Gene3D G3DSA:1.10.10.10 89 208 4.5E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2804 4a999bbe27a1df3e173b6c79cff90824 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 159 186 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_1733 92c0e14caeb1ad9415a6dc222b493d3d 135 Gene3D G3DSA:1.10.10.10 2 129 8.0E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1733 92c0e14caeb1ad9415a6dc222b493d3d 135 SMART SM00347 29 135 3.7E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_1733 92c0e14caeb1ad9415a6dc222b493d3d 135 SUPERFAMILY SSF46785 11 125 1.62E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1733 92c0e14caeb1ad9415a6dc222b493d3d 135 Pfam PF12802 MarR family 34 96 5.9E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_1733 92c0e14caeb1ad9415a6dc222b493d3d 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 56 72 1.3E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_1733 92c0e14caeb1ad9415a6dc222b493d3d 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 88 1.3E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_1733 92c0e14caeb1ad9415a6dc222b493d3d 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 108 1.3E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_3241 a1e03800481298e0b51f094b0e704eca 215 SUPERFAMILY SSF140931 16 128 6.54E-14 T 14-10-2018 IPR036597 Fido-like domain superfamily Tharo_3241 a1e03800481298e0b51f094b0e704eca 215 Gene3D G3DSA:1.10.3290.10 4 131 3.3E-15 T 14-10-2018 IPR036597 Fido-like domain superfamily Tharo_3241 a1e03800481298e0b51f094b0e704eca 215 Pfam PF02661 Fic/DOC family 10 72 2.1E-6 T 14-10-2018 IPR003812 Fido domain Tharo_1047 a5966ae01a063a3cde9b9d695211ab4b 96 SUPERFAMILY SSF50129 1 95 3.2E-35 T 14-10-2018 IPR011032 GroES-like superfamily Tharo_1047 a5966ae01a063a3cde9b9d695211ab4b 96 PRINTS PR00297 10kDa chaperonin signature 25 46 4.6E-34 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Tharo_1047 a5966ae01a063a3cde9b9d695211ab4b 96 PRINTS PR00297 10kDa chaperonin signature 81 94 4.6E-34 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Tharo_1047 a5966ae01a063a3cde9b9d695211ab4b 96 PRINTS PR00297 10kDa chaperonin signature 3 18 4.6E-34 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Tharo_1047 a5966ae01a063a3cde9b9d695211ab4b 96 PRINTS PR00297 10kDa chaperonin signature 60 72 4.6E-34 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Tharo_1047 a5966ae01a063a3cde9b9d695211ab4b 96 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 27.297 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Tharo_1047 a5966ae01a063a3cde9b9d695211ab4b 96 Pfam PF00166 Chaperonin 10 Kd subunit 2 94 4.1E-36 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Tharo_1047 a5966ae01a063a3cde9b9d695211ab4b 96 Gene3D G3DSA:2.30.33.40 1 96 1.8E-39 T 14-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 Tharo_1047 a5966ae01a063a3cde9b9d695211ab4b 96 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 14-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 Tharo_1047 a5966ae01a063a3cde9b9d695211ab4b 96 SMART SM00883 2 94 4.6E-59 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Tharo_0983 befb799fa1558b4954505bbdbc1b0e87 334 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 29 283 1.2E-99 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 Tharo_0983 befb799fa1558b4954505bbdbc1b0e87 334 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 29 312 1.3E-107 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 Tharo_0983 befb799fa1558b4954505bbdbc1b0e87 334 SUPERFAMILY SSF53850 32 264 1.78E-6 T 14-10-2018 Tharo_0983 befb799fa1558b4954505bbdbc1b0e87 334 Gene3D G3DSA:3.40.190.170 24 325 3.5E-104 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily Tharo_0983 befb799fa1558b4954505bbdbc1b0e87 334 PIRSF PIRSF006470 1 329 1.5E-138 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 Tharo_2478 06df8d2b3abaf251d3ede15fa32f2c91 162 SUPERFAMILY SSF55826 11 158 5.1E-38 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 Tharo_2478 06df8d2b3abaf251d3ede15fa32f2c91 162 PIRSF PIRSF006181 6 162 4.8E-45 T 14-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC Tharo_2478 06df8d2b3abaf251d3ede15fa32f2c91 162 Gene3D G3DSA:3.90.960.10 4 162 5.1E-43 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 Tharo_2478 06df8d2b3abaf251d3ede15fa32f2c91 162 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 11 159 2.2E-47 T 14-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC Tharo_2478 06df8d2b3abaf251d3ede15fa32f2c91 162 Pfam PF04073 Aminoacyl-tRNA editing domain 42 151 1.4E-22 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 Tharo_0002 c141e9a3280303be82860ce4088d4764 373 Pfam PF02767 DNA polymerase III beta subunit, central domain 132 250 1.3E-26 T 14-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 Tharo_0002 c141e9a3280303be82860ce4088d4764 373 Gene3D G3DSA:3.10.150.10 256 373 1.7E-37 T 14-10-2018 Tharo_0002 c141e9a3280303be82860ce4088d4764 373 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 4 372 4.9E-94 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 Tharo_0002 c141e9a3280303be82860ce4088d4764 373 Gene3D G3DSA:3.10.150.10 125 255 3.9E-35 T 14-10-2018 Tharo_0002 c141e9a3280303be82860ce4088d4764 373 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 253 372 4.2E-33 T 14-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 Tharo_0002 c141e9a3280303be82860ce4088d4764 373 SUPERFAMILY SSF55979 4 120 1.55E-25 T 14-10-2018 Tharo_0002 c141e9a3280303be82860ce4088d4764 373 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 4 120 1.4E-31 T 14-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 Tharo_0002 c141e9a3280303be82860ce4088d4764 373 Gene3D G3DSA:3.10.150.10 2 123 8.4E-38 T 14-10-2018 Tharo_0002 c141e9a3280303be82860ce4088d4764 373 PIRSF PIRSF000804 2 373 2.8E-112 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 Tharo_0002 c141e9a3280303be82860ce4088d4764 373 SMART SM00480 18 369 1.3E-115 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 Tharo_0002 c141e9a3280303be82860ce4088d4764 373 SUPERFAMILY SSF55979 252 373 5.83E-37 T 14-10-2018 Tharo_0002 c141e9a3280303be82860ce4088d4764 373 SUPERFAMILY SSF55979 129 251 1.23E-25 T 14-10-2018 Tharo_2895 65a6d42c98d8bb834dd6a5dc8e53e570 94 SUPERFAMILY SSF47413 8 83 3.75E-22 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_2895 65a6d42c98d8bb834dd6a5dc8e53e570 94 Pfam PF01381 Helix-turn-helix 18 66 4.6E-6 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_2895 65a6d42c98d8bb834dd6a5dc8e53e570 94 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 3 79 5.4E-30 T 14-10-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 Tharo_2895 65a6d42c98d8bb834dd6a5dc8e53e570 94 SMART SM00530 12 67 8.7E-4 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_2895 65a6d42c98d8bb834dd6a5dc8e53e570 94 Gene3D G3DSA:1.10.260.40 1 89 7.2E-26 T 14-10-2018 Tharo_0453 fda78db8c9b44927110b44b2c254baec 281 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 22 131 2.7E-45 T 14-10-2018 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 Tharo_0453 fda78db8c9b44927110b44b2c254baec 281 SUPERFAMILY SSF55620 182 265 1.04E-8 T 14-10-2018 Tharo_0453 fda78db8c9b44927110b44b2c254baec 281 Gene3D G3DSA:3.30.1130.10 22 137 9.4E-42 T 14-10-2018 Tharo_0453 fda78db8c9b44927110b44b2c254baec 281 Pfam PF14489 QueF-like protein 194 268 4.4E-24 T 14-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 Tharo_0453 fda78db8c9b44927110b44b2c254baec 281 TIGRFAM TIGR03138 QueF: queuine synthase 12 281 7.9E-115 T 14-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 Tharo_0453 fda78db8c9b44927110b44b2c254baec 281 Hamap MF_00817 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 281 136.683 T 14-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 Tharo_0453 fda78db8c9b44927110b44b2c254baec 281 Gene3D G3DSA:3.30.1130.10 146 281 1.2E-53 T 14-10-2018 Tharo_0453 fda78db8c9b44927110b44b2c254baec 281 PIRSF PIRSF004750 8 281 5.1E-114 T 14-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 Tharo_2897 46e3534d67a08e7ceefb5c0923472fa9 461 Gene3D G3DSA:3.30.160.390 5 111 1.2E-8 T 14-10-2018 IPR038488 Integrase, DNA-binding domain superfamily Tharo_2897 46e3534d67a08e7ceefb5c0923472fa9 461 Pfam PF13356 Arm DNA-binding domain 27 93 3.6E-11 T 14-10-2018 IPR025166 Integrase, DNA-binding domain Tharo_2897 46e3534d67a08e7ceefb5c0923472fa9 461 SUPERFAMILY SSF56349 162 428 1.09E-34 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Tharo_2897 46e3534d67a08e7ceefb5c0923472fa9 461 Gene3D G3DSA:1.10.443.10 244 437 9.6E-24 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Tharo_2897 46e3534d67a08e7ceefb5c0923472fa9 461 Pfam PF00589 Phage integrase family 262 420 2.6E-15 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Tharo_0951 14171bdf62e6b4f475af17a6e8b3daa7 83 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 9 77 1.1E-11 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Tharo_0951 14171bdf62e6b4f475af17a6e8b3daa7 83 SUPERFAMILY SSF143120 10 75 1.7E-9 T 14-10-2018 IPR036165 YefM-like superfamily Tharo_0951 14171bdf62e6b4f475af17a6e8b3daa7 83 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 9 59 3.1E-6 T 14-10-2018 Tharo_0556 0e4ff105eac6ee7f8f2ed72e9dda2a44 572 SUPERFAMILY SSF48452 325 423 2.23E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_0556 0e4ff105eac6ee7f8f2ed72e9dda2a44 572 SUPERFAMILY SSF48452 160 316 2.15E-17 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_0556 0e4ff105eac6ee7f8f2ed72e9dda2a44 572 Pfam PF14559 Tetratricopeptide repeat 505 559 1.1E-6 T 14-10-2018 Tharo_0556 0e4ff105eac6ee7f8f2ed72e9dda2a44 572 Gene3D G3DSA:1.25.40.10 390 567 1.7E-29 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_0556 0e4ff105eac6ee7f8f2ed72e9dda2a44 572 Pfam PF13432 Tetratricopeptide repeat 428 493 2.4E-6 T 14-10-2018 Tharo_0556 0e4ff105eac6ee7f8f2ed72e9dda2a44 572 SUPERFAMILY SSF48452 395 560 1.06E-24 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_0556 0e4ff105eac6ee7f8f2ed72e9dda2a44 572 Gene3D G3DSA:1.25.40.10 131 381 3.3E-22 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_0556 0e4ff105eac6ee7f8f2ed72e9dda2a44 572 SMART SM00028 186 219 51.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Tharo_0556 0e4ff105eac6ee7f8f2ed72e9dda2a44 572 SMART SM00028 493 526 15.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Tharo_0556 0e4ff105eac6ee7f8f2ed72e9dda2a44 572 SMART SM00028 458 492 110.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Tharo_0556 0e4ff105eac6ee7f8f2ed72e9dda2a44 572 SMART SM00028 424 457 51.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Tharo_0556 0e4ff105eac6ee7f8f2ed72e9dda2a44 572 SMART SM00028 527 559 130.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Tharo_0556 0e4ff105eac6ee7f8f2ed72e9dda2a44 572 Pfam PF13429 Tetratricopeptide repeat 224 337 3.5E-6 T 14-10-2018 Tharo_1386 f56fa473470926f4cb567ad5b9fdc2bc 131 Pfam PF04241 Protein of unknown function (DUF423) 19 105 1.7E-28 T 14-10-2018 IPR006696 Protein of unknown function DUF423 Tharo_1322 9e8dd8a850778645b843788fc2c2d1c7 547 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 178 193 1.1E-5 T 14-10-2018 Tharo_1322 9e8dd8a850778645b843788fc2c2d1c7 547 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 1.1E-5 T 14-10-2018 Tharo_1322 9e8dd8a850778645b843788fc2c2d1c7 547 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 442 545 4.1E-51 T 14-10-2018 Tharo_1322 9e8dd8a850778645b843788fc2c2d1c7 547 SUPERFAMILY SSF54373 210 305 9.42E-38 T 14-10-2018 Tharo_1322 9e8dd8a850778645b843788fc2c2d1c7 547 Pfam PF13450 NAD(P)-binding Rossmann-like domain 12 57 5.5E-7 T 14-10-2018 Tharo_1322 9e8dd8a850778645b843788fc2c2d1c7 547 SUPERFAMILY SSF51905 1 444 1.09E-53 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1322 9e8dd8a850778645b843788fc2c2d1c7 547 Gene3D G3DSA:3.30.70.20 447 542 1.4E-39 T 14-10-2018 Tharo_1322 9e8dd8a850778645b843788fc2c2d1c7 547 Gene3D G3DSA:3.30.9.90 79 446 3.2E-198 T 14-10-2018 Tharo_1322 9e8dd8a850778645b843788fc2c2d1c7 547 SUPERFAMILY SSF54862 446 546 4.61E-29 T 14-10-2018 Tharo_1322 9e8dd8a850778645b843788fc2c2d1c7 547 Gene3D G3DSA:3.50.50.60 7 384 3.2E-198 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_2574 f311afb113c09c7fb318a65d725e0985 181 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 180 3.0E-77 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Tharo_2574 f311afb113c09c7fb318a65d725e0985 181 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 2 177 1.4E-84 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Tharo_2574 f311afb113c09c7fb318a65d725e0985 181 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 5 174 6.6E-76 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Tharo_2574 f311afb113c09c7fb318a65d725e0985 181 SUPERFAMILY SSF51182 1 178 1.33E-79 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily Tharo_2574 f311afb113c09c7fb318a65d725e0985 181 Gene3D G3DSA:2.60.120.10 1 181 3.1E-76 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Tharo_2145 47852f6fceff8faaddde2bb67c9fdb2f 603 Gene3D G3DSA:3.40.50.300 1 265 4.4E-13 T 14-10-2018 Tharo_2145 47852f6fceff8faaddde2bb67c9fdb2f 603 Pfam PF13476 AAA domain 15 87 7.1E-7 T 14-10-2018 IPR038729 Rad50/SbcC-type AAA domain Tharo_2145 47852f6fceff8faaddde2bb67c9fdb2f 603 SUPERFAMILY SSF52540 1 532 1.06E-14 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0399 25797af56865747ee56d44692355fd23 743 Gene3D G3DSA:3.30.450.20 16 137 1.5E-26 T 14-10-2018 Tharo_0399 25797af56865747ee56d44692355fd23 743 Pfam PF02203 Tar ligand binding domain homologue 163 309 1.8E-8 T 14-10-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 Tharo_0399 25797af56865747ee56d44692355fd23 743 SUPERFAMILY SSF55785 23 114 8.55E-28 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_0399 25797af56865747ee56d44692355fd23 743 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 520 547 4.4E-58 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_0399 25797af56865747ee56d44692355fd23 743 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 597 626 4.4E-58 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_0399 25797af56865747ee56d44692355fd23 743 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 162 187 4.4E-58 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_0399 25797af56865747ee56d44692355fd23 743 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 443 472 4.4E-58 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_0399 25797af56865747ee56d44692355fd23 743 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 549 578 4.4E-58 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_0399 25797af56865747ee56d44692355fd23 743 SUPERFAMILY SSF58104 392 670 1.31E-68 T 14-10-2018 Tharo_0399 25797af56865747ee56d44692355fd23 743 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 24 114 2.5E-15 T 14-10-2018 IPR000014 PAS domain Tharo_0399 25797af56865747ee56d44692355fd23 743 Pfam PF08447 PAS fold 31 114 1.2E-15 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 Tharo_0399 25797af56865747ee56d44692355fd23 743 SMART SM00283 422 669 1.2E-82 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_0399 25797af56865747ee56d44692355fd23 743 Gene3D G3DSA:1.10.287.950 370 671 4.0E-82 T 14-10-2018 Tharo_0399 25797af56865747ee56d44692355fd23 743 SMART SM00304 369 421 1.7E-5 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_0399 25797af56865747ee56d44692355fd23 743 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 483 637 4.0E-48 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_1239 43f925855e6c09abb7ce6a9e2cba2c52 380 Gene3D G3DSA:3.30.310.170 256 379 5.6E-12 T 14-10-2018 Tharo_1239 43f925855e6c09abb7ce6a9e2cba2c52 380 Pfam PF06804 NlpB/DapX lipoprotein 40 375 6.7E-49 T 14-10-2018 IPR010653 NlpB/DapX lipoprotein Tharo_1515 b2a7621f7dd4a64d9ca22683d7603554 161 SUPERFAMILY SSF54292 5 80 3.15E-23 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Tharo_1515 b2a7621f7dd4a64d9ca22683d7603554 161 Pfam PF01799 [2Fe-2S] binding domain 75 147 3.1E-28 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Tharo_1515 b2a7621f7dd4a64d9ca22683d7603554 161 Gene3D G3DSA:3.10.20.30 1 78 6.1E-33 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Tharo_1515 b2a7621f7dd4a64d9ca22683d7603554 161 TIGRFAM TIGR03193 4hydroxCoAred: 4-hydroxybenzoyl-CoA reductase, gamma subunit 4 151 1.2E-89 T 14-10-2018 IPR017606 4-hydroxybenzoyl-CoA reductase, gamma subunit KEGG: 00362+1.3.7.9|KEGG: 00627+1.3.7.9|MetaCyc: PWY-6080|MetaCyc: PWY-7046 Tharo_1515 b2a7621f7dd4a64d9ca22683d7603554 161 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 65 3.1E-8 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Tharo_1515 b2a7621f7dd4a64d9ca22683d7603554 161 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 41 49 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Tharo_1515 b2a7621f7dd4a64d9ca22683d7603554 161 SUPERFAMILY SSF47741 86 153 3.01E-29 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily Tharo_1515 b2a7621f7dd4a64d9ca22683d7603554 161 Gene3D G3DSA:1.10.150.120 79 161 5.3E-34 T 14-10-2018 Tharo_1450 0ef7ac3557a59e3b4ae5e21be4c9e663 381 Pfam PF04143 Sulphur transport 45 371 2.7E-55 T 14-10-2018 IPR007272 Sulphur transport domain Tharo_2299 3434ecd4489b97bf9a818533dfffff78 69 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 1 45 5.7E-22 T 14-10-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type Tharo_2299 3434ecd4489b97bf9a818533dfffff78 69 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 2 45 1.6E-22 T 14-10-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type Tharo_1480 8ca2414cca2847fe6f3e9eb3a1b4c010 114 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 6 101 7.4E-15 T 14-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_1480 8ca2414cca2847fe6f3e9eb3a1b4c010 114 SUPERFAMILY SSF81343 3 114 1.31E-28 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_1480 8ca2414cca2847fe6f3e9eb3a1b4c010 114 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 8 112 2.6E-37 T 14-10-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 Tharo_1480 8ca2414cca2847fe6f3e9eb3a1b4c010 114 PIRSF PIRSF000169 1 114 5.5E-36 T 14-10-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 Tharo_1480 8ca2414cca2847fe6f3e9eb3a1b4c010 114 Gene3D G3DSA:1.20.1300.10 1 114 4.3E-32 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_1638 1a065322355c00c1cf315d0e1fe67fbf 148 PIRSF PIRSF032131 1 148 3.6E-44 T 14-10-2018 IPR009562 Protein of unknown function DUF1178 Tharo_1638 1a065322355c00c1cf315d0e1fe67fbf 148 Pfam PF06676 Protein of unknown function (DUF1178) 2 143 5.5E-47 T 14-10-2018 IPR009562 Protein of unknown function DUF1178 Tharo_3412 10bfbd924ec2e7f047e12da836c54328 852 TIGRFAM TIGR00929 VirB4_CagE: type IV secretion/conjugal transfer ATPase, VirB4 family 36 841 2.4E-228 T 14-10-2018 IPR004346 CagE, TrbE, VirB component of type IV transporter system GO:0005524 Tharo_3412 10bfbd924ec2e7f047e12da836c54328 852 Pfam PF03135 CagE, TrbE, VirB family, component of type IV transporter system 221 431 4.1E-58 T 14-10-2018 IPR018145 CagE, TrbE, VirB component of type IV transporter system, central domain GO:0005524 Tharo_3412 10bfbd924ec2e7f047e12da836c54328 852 SMART SM00382 487 748 3.1E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_3412 10bfbd924ec2e7f047e12da836c54328 852 Gene3D G3DSA:3.40.50.300 613 813 1.5E-24 T 14-10-2018 Tharo_3412 10bfbd924ec2e7f047e12da836c54328 852 SUPERFAMILY SSF52540 447 797 6.18E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0158 945596a27e64a0379636468914f244aa 350 Gene3D G3DSA:3.30.420.10 125 305 2.3E-10 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_0158 945596a27e64a0379636468914f244aa 350 SUPERFAMILY SSF53098 128 291 7.08E-41 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_0158 945596a27e64a0379636468914f244aa 350 Pfam PF00665 Integrase core domain 129 245 2.5E-19 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Tharo_2655 945596a27e64a0379636468914f244aa 350 Gene3D G3DSA:3.30.420.10 125 305 2.3E-10 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_2655 945596a27e64a0379636468914f244aa 350 SUPERFAMILY SSF53098 128 291 7.08E-41 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_2655 945596a27e64a0379636468914f244aa 350 Pfam PF00665 Integrase core domain 129 245 2.5E-19 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Tharo_2431 8c6680efb058f8f27afb3c39078f731b 484 Gene3D G3DSA:2.40.33.10 71 167 3.2E-160 T 14-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Tharo_2431 8c6680efb058f8f27afb3c39078f731b 484 ProSitePatterns PS00110 Pyruvate kinase active site signature. 213 225 - T 14-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Tharo_2431 8c6680efb058f8f27afb3c39078f731b 484 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 471 2.8E-158 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Tharo_2431 8c6680efb058f8f27afb3c39078f731b 484 SUPERFAMILY SSF51621 2 337 2.09E-94 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Tharo_2431 8c6680efb058f8f27afb3c39078f731b 484 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 469 5.4E-29 T 14-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Tharo_2431 8c6680efb058f8f27afb3c39078f731b 484 Pfam PF00224 Pyruvate kinase, barrel domain 3 336 1.8E-120 T 14-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Tharo_2431 8c6680efb058f8f27afb3c39078f731b 484 Gene3D G3DSA:3.40.1380.20 334 467 3.2E-160 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Tharo_2431 8c6680efb058f8f27afb3c39078f731b 484 SUPERFAMILY SSF50800 71 163 4.88E-23 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily Tharo_2431 8c6680efb058f8f27afb3c39078f731b 484 Gene3D G3DSA:3.20.20.60 3 333 3.2E-160 T 14-10-2018 Tharo_2431 8c6680efb058f8f27afb3c39078f731b 484 PRINTS PR01050 Pyruvate kinase family signature 242 266 2.6E-61 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Tharo_2431 8c6680efb058f8f27afb3c39078f731b 484 PRINTS PR01050 Pyruvate kinase family signature 267 291 2.6E-61 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Tharo_2431 8c6680efb058f8f27afb3c39078f731b 484 PRINTS PR01050 Pyruvate kinase family signature 292 310 2.6E-61 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Tharo_2431 8c6680efb058f8f27afb3c39078f731b 484 PRINTS PR01050 Pyruvate kinase family signature 185 199 2.6E-61 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Tharo_2431 8c6680efb058f8f27afb3c39078f731b 484 PRINTS PR01050 Pyruvate kinase family signature 215 241 2.6E-61 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Tharo_2431 8c6680efb058f8f27afb3c39078f731b 484 PRINTS PR01050 Pyruvate kinase family signature 60 76 2.6E-61 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Tharo_2431 8c6680efb058f8f27afb3c39078f731b 484 PRINTS PR01050 Pyruvate kinase family signature 311 327 2.6E-61 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Tharo_2431 8c6680efb058f8f27afb3c39078f731b 484 SUPERFAMILY SSF52935 321 472 9.16E-36 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Tharo_3446 06270e29ce4ed405d85e5754b4ce9ca1 235 SUPERFAMILY SSF53098 174 224 2.09E-6 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_3446 06270e29ce4ed405d85e5754b4ce9ca1 235 Pfam PF09039 Mu DNA binding, I gamma subdomain 99 161 1.5E-4 T 14-10-2018 IPR015126 Mu DNA binding, I gamma subdomain Tharo_3446 06270e29ce4ed405d85e5754b4ce9ca1 235 Gene3D G3DSA:3.30.420.10 172 232 1.5E-12 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_3446 06270e29ce4ed405d85e5754b4ce9ca1 235 Pfam PF13518 Helix-turn-helix domain 26 85 9.4E-11 T 14-10-2018 Tharo_2580 f3079bc8a0b1769a4a7e7ea976a5e250 415 Pfam PF13416 Bacterial extracellular solute-binding protein 47 336 1.1E-19 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein Tharo_2580 f3079bc8a0b1769a4a7e7ea976a5e250 415 Gene3D G3DSA:3.40.190.10 134 409 2.2E-68 T 14-10-2018 Tharo_2580 f3079bc8a0b1769a4a7e7ea976a5e250 415 SUPERFAMILY SSF53850 25 412 1.55E-37 T 14-10-2018 Tharo_2580 f3079bc8a0b1769a4a7e7ea976a5e250 415 Gene3D G3DSA:3.40.190.10 31 369 2.2E-68 T 14-10-2018 Tharo_2930 993baeceeacd9a64e3f2537a9d41083b 116 Gene3D G3DSA:1.10.760.10 27 115 2.1E-15 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_2930 993baeceeacd9a64e3f2537a9d41083b 116 SUPERFAMILY SSF46626 2 112 1.17E-15 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_2930 993baeceeacd9a64e3f2537a9d41083b 116 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 29 110 1.4E-13 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_1643 823e7e8e68ac6741d8331097cb153b0a 382 Gene3D G3DSA:3.40.190.10 156 275 3.7E-54 T 14-10-2018 Tharo_1643 823e7e8e68ac6741d8331097cb153b0a 382 PIRSF PIRSF027386 51 379 5.3E-98 T 14-10-2018 IPR027024 ABC-type uncharacterised transport system, substrate-binding component, TM0202 type Tharo_1643 823e7e8e68ac6741d8331097cb153b0a 382 Gene3D G3DSA:3.40.190.10 79 375 3.7E-54 T 14-10-2018 Tharo_1643 823e7e8e68ac6741d8331097cb153b0a 382 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 104 287 1.7E-7 T 14-10-2018 Tharo_1643 823e7e8e68ac6741d8331097cb153b0a 382 SUPERFAMILY SSF53850 80 375 3.82E-24 T 14-10-2018 Tharo_2031 67d1e44bcf59fec76f0db5ab82dfef19 277 Pfam PF00494 Squalene/phytoene synthase 13 264 1.9E-85 T 14-10-2018 Tharo_2031 67d1e44bcf59fec76f0db5ab82dfef19 277 Gene3D G3DSA:1.10.600.10 2 273 2.1E-91 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily Tharo_2031 67d1e44bcf59fec76f0db5ab82dfef19 277 SUPERFAMILY SSF48576 3 276 8.8E-97 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily Tharo_2031 67d1e44bcf59fec76f0db5ab82dfef19 277 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 152 177 - T 14-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 Tharo_2031 67d1e44bcf59fec76f0db5ab82dfef19 277 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 10 275 2.8E-123 T 14-10-2018 IPR017828 Squalene synthase HpnD-like GO:0016117|GO:0016767 Tharo_1767 1e83954cdf167ea9fc45b2ac77b8b96a 240 SUPERFAMILY SSF55729 82 236 1.11E-17 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Tharo_1767 1e83954cdf167ea9fc45b2ac77b8b96a 240 Hamap MF_00689 Aspartate/glutamate leucyltransferase [bpt]. 8 235 39.498 T 14-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 Tharo_1767 1e83954cdf167ea9fc45b2ac77b8b96a 240 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 108 229 5.3E-38 T 14-10-2018 IPR007472 N-end rule aminoacyl transferase, C-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 Tharo_1767 1e83954cdf167ea9fc45b2ac77b8b96a 240 PIRSF PIRSF037208 1 240 3.8E-88 T 14-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 Tharo_1767 1e83954cdf167ea9fc45b2ac77b8b96a 240 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 18 88 2.1E-20 T 14-10-2018 IPR007471 N-end aminoacyl transferase, N-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 Tharo_0670 63bb078fd1f4c0274ace2509e140325f 413 Gene3D G3DSA:3.30.420.40 208 411 1.7E-64 T 14-10-2018 Tharo_0670 63bb078fd1f4c0274ace2509e140325f 413 PIRSF PIRSF000722 14 411 1.5E-122 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0670 63bb078fd1f4c0274ace2509e140325f 413 Hamap MF_00020 Acetate kinase [ackA]. 1 410 139.76 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0670 63bb078fd1f4c0274ace2509e140325f 413 Gene3D G3DSA:3.30.420.40 15 204 1.4E-54 T 14-10-2018 Tharo_0670 63bb078fd1f4c0274ace2509e140325f 413 Pfam PF00871 Acetokinase family 16 400 1.6E-98 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0670 63bb078fd1f4c0274ace2509e140325f 413 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 17 28 - T 14-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0670 63bb078fd1f4c0274ace2509e140325f 413 PRINTS PR00471 Acetate kinase family signature 185 198 2.8E-32 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0670 63bb078fd1f4c0274ace2509e140325f 413 PRINTS PR00471 Acetate kinase family signature 17 28 2.8E-32 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0670 63bb078fd1f4c0274ace2509e140325f 413 PRINTS PR00471 Acetate kinase family signature 388 400 2.8E-32 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0670 63bb078fd1f4c0274ace2509e140325f 413 PRINTS PR00471 Acetate kinase family signature 314 327 2.8E-32 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0670 63bb078fd1f4c0274ace2509e140325f 413 PRINTS PR00471 Acetate kinase family signature 214 235 2.8E-32 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0670 63bb078fd1f4c0274ace2509e140325f 413 PRINTS PR00471 Acetate kinase family signature 336 352 2.8E-32 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0670 63bb078fd1f4c0274ace2509e140325f 413 SUPERFAMILY SSF53067 16 207 2.59E-53 T 14-10-2018 Tharo_0670 63bb078fd1f4c0274ace2509e140325f 413 TIGRFAM TIGR00016 ackA: acetate kinase 16 402 1.7E-101 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0670 63bb078fd1f4c0274ace2509e140325f 413 SUPERFAMILY SSF53067 171 405 2.03E-68 T 14-10-2018 Tharo_2905 8376fc39533aa8ab253ad6dec102b9f3 100 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 33 91 1.8E-14 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_2905 8376fc39533aa8ab253ad6dec102b9f3 100 SUPERFAMILY SSF46626 7 93 3.0E-10 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_2905 8376fc39533aa8ab253ad6dec102b9f3 100 Gene3D G3DSA:1.10.760.10 31 98 4.1E-15 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_2694 ddb151a1df64c7d8148d9cc35dab1a88 167 Pfam PF00436 Single-strand binding protein family 4 108 5.7E-42 T 14-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 Tharo_2694 ddb151a1df64c7d8148d9cc35dab1a88 167 Gene3D G3DSA:2.40.50.140 2 144 1.4E-46 T 14-10-2018 Tharo_2694 ddb151a1df64c7d8148d9cc35dab1a88 167 SUPERFAMILY SSF50249 3 167 3.15E-58 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_2694 ddb151a1df64c7d8148d9cc35dab1a88 167 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 167 3.9E-55 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 Tharo_2694 ddb151a1df64c7d8148d9cc35dab1a88 167 Hamap MF_00984 Single-stranded DNA-binding protein. 4 112 38.107 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 Tharo_0455 2af409f2238cadc8aa808006118e59ea 378 Gene3D G3DSA:1.10.3210.10 173 356 5.0E-19 T 14-10-2018 Tharo_0455 2af409f2238cadc8aa808006118e59ea 378 SUPERFAMILY SSF109604 162 365 3.45E-30 T 14-10-2018 Tharo_0455 2af409f2238cadc8aa808006118e59ea 378 Pfam PF08668 HDOD domain 191 252 4.2E-10 T 14-10-2018 IPR013976 Metal-dependent hydrolase HDOD Tharo_2163 37ec30dfed2d631b7283408e7aa9bb24 135 Gene3D G3DSA:3.10.580.10 1 127 1.4E-27 T 14-10-2018 Tharo_2163 37ec30dfed2d631b7283408e7aa9bb24 135 Pfam PF00571 CBS domain 74 127 2.0E-9 T 14-10-2018 IPR000644 CBS domain Tharo_2163 37ec30dfed2d631b7283408e7aa9bb24 135 Pfam PF00571 CBS domain 7 60 7.9E-9 T 14-10-2018 IPR000644 CBS domain Tharo_2163 37ec30dfed2d631b7283408e7aa9bb24 135 SUPERFAMILY SSF54631 2 127 1.77E-30 T 14-10-2018 Tharo_2163 37ec30dfed2d631b7283408e7aa9bb24 135 SMART SM00116 14 62 1.2E-4 T 14-10-2018 IPR000644 CBS domain Tharo_2163 37ec30dfed2d631b7283408e7aa9bb24 135 SMART SM00116 81 128 1.2E-5 T 14-10-2018 IPR000644 CBS domain Tharo_0306 f5061af3efb6f8c1bddb11b37cca05bd 224 Pfam PF11444 Protein of unknown function (DUF2895) 6 206 1.5E-89 T 14-10-2018 IPR021548 Protein of unknown function DUF2895 Tharo_0306 f5061af3efb6f8c1bddb11b37cca05bd 224 TIGRFAM TIGR03746 conj_TIGR03746: integrating conjugative element protein, PFL_4703 family 4 207 2.6E-95 T 14-10-2018 IPR021548 Protein of unknown function DUF2895 Tharo_1066 6758dc6f04f72105ca5229164fa80764 456 Gene3D G3DSA:1.20.120.140 4 305 8.1E-123 T 14-10-2018 Tharo_1066 6758dc6f04f72105ca5229164fa80764 456 SMART SM00382 99 270 1.6E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1066 6758dc6f04f72105ca5229164fa80764 456 SMART SM00963 1 86 5.6E-36 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Tharo_1066 6758dc6f04f72105ca5229164fa80764 456 Gene3D G3DSA:1.10.260.30 328 452 1.0E-42 T 14-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 Tharo_1066 6758dc6f04f72105ca5229164fa80764 456 Pfam PF00448 SRP54-type protein, GTPase domain 100 296 9.0E-73 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Tharo_1066 6758dc6f04f72105ca5229164fa80764 456 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 5.0E-22 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Tharo_1066 6758dc6f04f72105ca5229164fa80764 456 SUPERFAMILY SSF47446 329 431 2.45E-33 T 14-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 Tharo_1066 6758dc6f04f72105ca5229164fa80764 456 SMART SM00962 100 296 8.1E-114 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Tharo_1066 6758dc6f04f72105ca5229164fa80764 456 Gene3D G3DSA:3.40.50.300 90 285 8.1E-123 T 14-10-2018 Tharo_1066 6758dc6f04f72105ca5229164fa80764 456 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Tharo_1066 6758dc6f04f72105ca5229164fa80764 456 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 430 4.2E-174 T 14-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 Tharo_1066 6758dc6f04f72105ca5229164fa80764 456 SUPERFAMILY SSF52540 42 358 9.11E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1066 6758dc6f04f72105ca5229164fa80764 456 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 440 33.231 T 14-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 Tharo_1066 6758dc6f04f72105ca5229164fa80764 456 Pfam PF02978 Signal peptide binding domain 329 428 1.6E-31 T 14-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 Tharo_2096 e585a1be58b547559e1f0a613dc49958 184 SUPERFAMILY SSF47598 23 68 7.78E-15 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Tharo_2096 e585a1be58b547559e1f0a613dc49958 184 Gene3D G3DSA:1.10.1220.10 9 70 1.2E-26 T 14-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 Tharo_2096 e585a1be58b547559e1f0a613dc49958 184 Pfam PF03869 Arc-like DNA binding domain 22 68 1.3E-19 T 14-10-2018 IPR005569 Arc-like DNA binding domain GO:0003677 Tharo_1784 7058d0d031adda2f0f8ff766e7af3538 70 Pfam PF07311 Dodecin 5 68 9.4E-30 T 14-10-2018 IPR009923 Dodecin Tharo_1784 7058d0d031adda2f0f8ff766e7af3538 70 SUPERFAMILY SSF89807 3 68 1.28E-25 T 14-10-2018 IPR036694 Dodecin-like superfamily Tharo_1784 7058d0d031adda2f0f8ff766e7af3538 70 Gene3D G3DSA:3.30.1660.10 2 69 7.6E-34 T 14-10-2018 IPR025543 Dodecin-like Tharo_0077 a5d707fd1ff26e6552f751b82ee52120 110 Gene3D G3DSA:3.30.2310.20 1 103 8.4E-18 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_0077 a5d707fd1ff26e6552f751b82ee52120 110 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 9 98 7.3E-12 T 14-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Tharo_1627 a8a2a1089a521b49fb6bb672fe0d1afe 615 Pfam PF01435 Peptidase family M48 106 317 4.9E-29 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 Tharo_1627 a8a2a1089a521b49fb6bb672fe0d1afe 615 Gene3D G3DSA:3.30.2010.10 98 188 1.5E-31 T 14-10-2018 Tharo_0073 3db23a2519e020b21226a589cc231d9c 94 PIRSF PIRSF028784 3 94 2.8E-27 T 14-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 Tharo_0073 3db23a2519e020b21226a589cc231d9c 94 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 36 87 9.6E-21 T 14-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 Tharo_0657 2851e83702df941f3022f4be4b7f6782 227 SUPERFAMILY SSF56784 10 224 3.93E-59 T 14-10-2018 IPR036412 HAD-like superfamily Tharo_0657 2851e83702df941f3022f4be4b7f6782 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 195 5.6E-36 T 14-10-2018 Tharo_0657 2851e83702df941f3022f4be4b7f6782 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 4.7E-15 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Tharo_0657 2851e83702df941f3022f4be4b7f6782 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 108 121 4.7E-15 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Tharo_0657 2851e83702df941f3022f4be4b7f6782 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 157 177 4.7E-15 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Tharo_0657 2851e83702df941f3022f4be4b7f6782 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 139 155 4.7E-15 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Tharo_0657 2851e83702df941f3022f4be4b7f6782 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 184 197 4.7E-15 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Tharo_0657 2851e83702df941f3022f4be4b7f6782 227 Gene3D G3DSA:1.10.150.240 25 94 5.6E-61 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 Tharo_0657 2851e83702df941f3022f4be4b7f6782 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 85 195 3.4E-14 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Tharo_0657 2851e83702df941f3022f4be4b7f6782 227 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 13 217 1.2E-65 T 14-10-2018 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic GO:0016791 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 Tharo_0657 2851e83702df941f3022f4be4b7f6782 227 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 108 189 3.1E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Tharo_0657 2851e83702df941f3022f4be4b7f6782 227 Gene3D G3DSA:3.40.50.1000 13 200 5.6E-61 T 14-10-2018 IPR023214 HAD superfamily Tharo_0657 2851e83702df941f3022f4be4b7f6782 227 Hamap MF_00495 Phosphoglycolate phosphatase [gph]. 10 225 36.311 T 14-10-2018 IPR037512 Phosphoglycolate phosphatase, prokaryotic GO:0005975|GO:0008967 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 Tharo_0148 cedb2cfff82e79856f6cd50e14c1318f 665 Gene3D G3DSA:1.10.10.160 107 182 4.2E-92 T 14-10-2018 IPR013986 DExx box DNA helicase domain superfamily Tharo_0148 cedb2cfff82e79856f6cd50e14c1318f 665 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 3 658 38.896 T 14-10-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 Tharo_0148 cedb2cfff82e79856f6cd50e14c1318f 665 Pfam PF13361 UvrD-like helicase C-terminal domain 270 606 2.5E-68 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Tharo_0148 cedb2cfff82e79856f6cd50e14c1318f 665 SUPERFAMILY SSF52540 5 629 2.59E-163 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0148 cedb2cfff82e79856f6cd50e14c1318f 665 Pfam PF00580 UvrD/REP helicase N-terminal domain 5 264 1.0E-70 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 Tharo_0148 cedb2cfff82e79856f6cd50e14c1318f 665 Gene3D G3DSA:3.40.50.300 273 625 7.4E-119 T 14-10-2018 Tharo_0148 cedb2cfff82e79856f6cd50e14c1318f 665 Gene3D G3DSA:3.40.50.300 5 266 4.2E-92 T 14-10-2018 Tharo_0148 cedb2cfff82e79856f6cd50e14c1318f 665 Gene3D G3DSA:1.10.486.10 376 537 7.4E-119 T 14-10-2018 Tharo_3109 6a3199f102b77ee5b7027715f90e4683 116 Pfam PF07883 Cupin domain 53 107 3.8E-8 T 14-10-2018 IPR013096 Cupin 2, conserved barrel Tharo_3109 6a3199f102b77ee5b7027715f90e4683 116 SUPERFAMILY SSF51182 19 111 1.88E-15 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily Tharo_3109 6a3199f102b77ee5b7027715f90e4683 116 Gene3D G3DSA:2.60.120.10 22 112 1.1E-32 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Tharo_0401 4af6a456cdf682d25319dc2751cab7c4 353 SUPERFAMILY SSF52172 5 111 2.7E-28 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_0401 4af6a456cdf682d25319dc2751cab7c4 353 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 6 345 40.704 T 14-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Tharo_0401 4af6a456cdf682d25319dc2751cab7c4 353 Gene3D G3DSA:3.40.50.180 151 351 3.1E-78 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal Tharo_0401 4af6a456cdf682d25319dc2751cab7c4 353 SUPERFAMILY SSF52738 159 346 2.22E-72 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal Tharo_0401 4af6a456cdf682d25319dc2751cab7c4 353 SMART SM00448 6 118 7.3E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_0401 4af6a456cdf682d25319dc2751cab7c4 353 Gene3D G3DSA:3.40.50.2300 4 135 4.6E-32 T 14-10-2018 Tharo_0401 4af6a456cdf682d25319dc2751cab7c4 353 PIRSF PIRSF000876 3 349 1.6E-134 T 14-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Tharo_0401 4af6a456cdf682d25319dc2751cab7c4 353 Pfam PF00072 Response regulator receiver domain 8 112 4.7E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_0401 4af6a456cdf682d25319dc2751cab7c4 353 Pfam PF01339 CheB methylesterase 162 340 1.4E-60 T 14-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Tharo_1724 56f3e44f53c4d77b65af83b92f8395dd 253 SUPERFAMILY SSF51206 27 161 4.45E-24 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like Tharo_1724 56f3e44f53c4d77b65af83b92f8395dd 253 SMART SM00100 34 152 3.5E-9 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Tharo_1724 56f3e44f53c4d77b65af83b92f8395dd 253 Pfam PF00027 Cyclic nucleotide-binding domain 53 137 2.6E-14 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Tharo_1724 56f3e44f53c4d77b65af83b92f8395dd 253 Pfam PF13545 Crp-like helix-turn-helix domain 172 243 3.1E-18 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Tharo_1724 56f3e44f53c4d77b65af83b92f8395dd 253 Gene3D G3DSA:1.10.10.10 167 243 2.1E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1724 56f3e44f53c4d77b65af83b92f8395dd 253 SUPERFAMILY SSF46785 170 244 1.41E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1724 56f3e44f53c4d77b65af83b92f8395dd 253 Gene3D G3DSA:2.60.120.10 23 166 9.3E-24 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Tharo_1724 56f3e44f53c4d77b65af83b92f8395dd 253 SMART SM00419 189 236 5.4E-7 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Tharo_1604 5b4c52538a0f0accb4647a05c0985f56 79 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site Tharo_1604 5b4c52538a0f0accb4647a05c0985f56 79 SUPERFAMILY SSF47336 1 77 4.97E-25 T 14-10-2018 IPR036736 ACP-like superfamily Tharo_1604 5b4c52538a0f0accb4647a05c0985f56 79 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 77 0.001 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 Tharo_1604 5b4c52538a0f0accb4647a05c0985f56 79 Gene3D G3DSA:1.10.1200.10 1 77 2.9E-30 T 14-10-2018 IPR036736 ACP-like superfamily Tharo_1604 5b4c52538a0f0accb4647a05c0985f56 79 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.719 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 Tharo_1604 5b4c52538a0f0accb4647a05c0985f56 79 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 75 1.9E-35 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 Tharo_1604 5b4c52538a0f0accb4647a05c0985f56 79 Pfam PF00550 Phosphopantetheine attachment site 6 73 1.7E-17 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain Tharo_0100 5e459dbb5154b49a2838a0d4d49df47f 365 Gene3D G3DSA:1.10.10.10 3 117 1.6E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0100 5e459dbb5154b49a2838a0d4d49df47f 365 SUPERFAMILY SSF53850 115 345 2.11E-17 T 14-10-2018 Tharo_0100 5e459dbb5154b49a2838a0d4d49df47f 365 SUPERFAMILY SSF46785 16 130 8.16E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0100 5e459dbb5154b49a2838a0d4d49df47f 365 Gene3D G3DSA:3.40.190.290 128 327 2.1E-6 T 14-10-2018 Tharo_0100 5e459dbb5154b49a2838a0d4d49df47f 365 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 24 80 4.0E-13 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0100 5e459dbb5154b49a2838a0d4d49df47f 365 Pfam PF12727 PBP superfamily domain 140 323 1.4E-51 T 14-10-2018 IPR024370 PBP domain Tharo_3347 a3eb4659f90dcd075cebbf806625a47b 399 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 61 294 1.8E-15 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Tharo_3347 a3eb4659f90dcd075cebbf806625a47b 399 Gene3D G3DSA:2.40.50.100 64 238 3.2E-49 T 14-10-2018 Tharo_3347 a3eb4659f90dcd075cebbf806625a47b 399 Gene3D G3DSA:2.40.420.20 316 376 3.2E-49 T 14-10-2018 Tharo_3347 a3eb4659f90dcd075cebbf806625a47b 399 SUPERFAMILY SSF111369 57 295 8.5E-9 T 14-10-2018 Tharo_3347 a3eb4659f90dcd075cebbf806625a47b 399 Gene3D G3DSA:1.10.287.470 98 203 3.2E-49 T 14-10-2018 Tharo_3347 a3eb4659f90dcd075cebbf806625a47b 399 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 114 390 1.4E-28 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Tharo_3347 a3eb4659f90dcd075cebbf806625a47b 399 Gene3D G3DSA:2.40.30.170 53 315 3.2E-49 T 14-10-2018 Tharo_3343 45d2145446103acfd201a67f5c7f2157 234 SUPERFAMILY SSF52540 4 227 1.16E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3343 45d2145446103acfd201a67f5c7f2157 234 Gene3D G3DSA:3.40.50.300 3 233 4.6E-65 T 14-10-2018 Tharo_3343 45d2145446103acfd201a67f5c7f2157 234 SMART SM00382 32 229 2.0E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_3343 45d2145446103acfd201a67f5c7f2157 234 Pfam PF00005 ABC transporter 23 174 2.5E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_3343 45d2145446103acfd201a67f5c7f2157 234 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_2865 a92a1d90d1da16a1782e5b062517f43a 345 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 144 314 2.7E-35 T 14-10-2018 IPR000160 GGDEF domain Tharo_2865 a92a1d90d1da16a1782e5b062517f43a 345 SUPERFAMILY SSF55073 149 316 1.65E-38 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_2865 a92a1d90d1da16a1782e5b062517f43a 345 SMART SM00267 133 315 2.8E-41 T 14-10-2018 IPR000160 GGDEF domain Tharo_2865 a92a1d90d1da16a1782e5b062517f43a 345 Gene3D G3DSA:3.30.70.270 132 314 7.9E-49 T 14-10-2018 Tharo_2865 a92a1d90d1da16a1782e5b062517f43a 345 Pfam PF00990 Diguanylate cyclase, GGDEF domain 145 311 2.4E-33 T 14-10-2018 IPR000160 GGDEF domain Tharo_0756 6c805cf9c42db558bae6390dd7c87dfa 291 Gene3D G3DSA:1.20.120.80 78 291 1.6E-66 T 14-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0756 6c805cf9c42db558bae6390dd7c87dfa 291 Pfam PF00510 Cytochrome c oxidase subunit III 13 290 3.0E-59 T 14-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0756 6c805cf9c42db558bae6390dd7c87dfa 291 Gene3D G3DSA:1.10.287.70 6 75 1.7E-18 T 14-10-2018 Tharo_0756 6c805cf9c42db558bae6390dd7c87dfa 291 SUPERFAMILY SSF81452 10 291 1.7E-80 T 14-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_1656 726260c2ec6d1a73968d9dc174009c45 375 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 172 363 7.4E-33 T 14-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 Tharo_1656 726260c2ec6d1a73968d9dc174009c45 375 Pfam PF00355 Rieske [2Fe-2S] domain 45 121 1.1E-11 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Tharo_1656 726260c2ec6d1a73968d9dc174009c45 375 SUPERFAMILY SSF55961 162 362 2.2E-42 T 14-10-2018 Tharo_1656 726260c2ec6d1a73968d9dc174009c45 375 SUPERFAMILY SSF50022 12 140 1.3E-32 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Tharo_1656 726260c2ec6d1a73968d9dc174009c45 375 Gene3D G3DSA:3.90.380.10 205 374 3.3E-10 T 14-10-2018 Tharo_1656 726260c2ec6d1a73968d9dc174009c45 375 Gene3D G3DSA:2.102.10.10 42 151 1.6E-20 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Tharo_1897 a1774f9b58d41f475926a84eec04a853 630 Gene3D G3DSA:1.10.8.60 327 404 2.8E-29 T 14-10-2018 Tharo_1897 a1774f9b58d41f475926a84eec04a853 630 Pfam PF01434 Peptidase family M41 387 595 8.0E-81 T 14-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 Tharo_1897 a1774f9b58d41f475926a84eec04a853 630 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 105 596 1.0E-241 T 14-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 Tharo_1897 a1774f9b58d41f475926a84eec04a853 630 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 602 37.462 T 14-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 Tharo_1897 a1774f9b58d41f475926a84eec04a853 630 SUPERFAMILY SSF52540 149 396 1.9E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1897 a1774f9b58d41f475926a84eec04a853 630 Gene3D G3DSA:3.40.50.300 145 325 3.0E-69 T 14-10-2018 Tharo_1897 a1774f9b58d41f475926a84eec04a853 630 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 193 325 1.5E-45 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Tharo_1897 a1774f9b58d41f475926a84eec04a853 630 SUPERFAMILY SSF140990 407 606 1.7E-75 T 14-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 Tharo_1897 a1774f9b58d41f475926a84eec04a853 630 Gene3D G3DSA:1.20.58.760 407 606 4.9E-75 T 14-10-2018 Tharo_1897 a1774f9b58d41f475926a84eec04a853 630 ProSitePatterns PS00674 AAA-protein family signature. 296 314 - T 14-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 Tharo_1897 a1774f9b58d41f475926a84eec04a853 630 Gene3D G3DSA:2.40.50.920 27 105 7.6E-8 T 14-10-2018 Tharo_1897 a1774f9b58d41f475926a84eec04a853 630 Pfam PF06480 FtsH Extracellular 9 75 3.6E-8 T 14-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 Tharo_1897 a1774f9b58d41f475926a84eec04a853 630 SMART SM00382 189 328 2.0E-25 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_3317 ec21a02fef86f93919bfcae4b685f8be 288 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 288 1.2E-82 T 14-10-2018 IPR005229 Conserved hypothetical protein CHP00255 Tharo_3317 ec21a02fef86f93919bfcae4b685f8be 288 Pfam PF03755 YicC-like family, N-terminal region 2 154 1.0E-37 T 14-10-2018 IPR013527 YicC-like, N-terminal Tharo_3317 ec21a02fef86f93919bfcae4b685f8be 288 Pfam PF08340 Domain of unknown function (DUF1732) 204 288 3.0E-35 T 14-10-2018 IPR013551 Domain of unknown function DUF1732 Tharo_2388 9d9b985a88988e5761924efd7a07efc1 440 SUPERFAMILY SSF57997 28 126 4.58E-6 T 14-10-2018 Tharo_2388 9d9b985a88988e5761924efd7a07efc1 440 SUPERFAMILY SSF51261 246 436 2.56E-42 T 14-10-2018 IPR011055 Duplicated hybrid motif Tharo_2388 9d9b985a88988e5761924efd7a07efc1 440 Gene3D G3DSA:2.70.70.10 305 438 4.5E-32 T 14-10-2018 IPR011055 Duplicated hybrid motif Tharo_2388 9d9b985a88988e5761924efd7a07efc1 440 Pfam PF01551 Peptidase family M23 339 433 8.5E-24 T 14-10-2018 IPR016047 Peptidase M23 Tharo_0761 daedcf1d185585250c16ee07d6dd0aa2 212 Gene3D G3DSA:3.40.30.10 49 208 1.6E-57 T 14-10-2018 Tharo_0761 daedcf1d185585250c16ee07d6dd0aa2 212 Pfam PF02630 SCO1/SenC 55 189 2.0E-40 T 14-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0761 daedcf1d185585250c16ee07d6dd0aa2 212 SUPERFAMILY SSF52833 54 210 6.22E-55 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_3244 93081c8e39a275916af91f2c5fcbb248 320 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 2 317 9.6E-130 T 14-10-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 Tharo_3244 93081c8e39a275916af91f2c5fcbb248 320 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 241 2.8E-41 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 Tharo_3244 93081c8e39a275916af91f2c5fcbb248 320 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 1 319 50.583 T 14-10-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 Tharo_3244 93081c8e39a275916af91f2c5fcbb248 320 Gene3D G3DSA:3.90.25.10 167 300 5.6E-120 T 14-10-2018 Tharo_3244 93081c8e39a275916af91f2c5fcbb248 320 SUPERFAMILY SSF51735 1 316 1.28E-59 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_3244 93081c8e39a275916af91f2c5fcbb248 320 Gene3D G3DSA:3.40.50.720 3 312 5.6E-120 T 14-10-2018 Tharo_2418 af51fd94a2cd98cf92b00bdd766d3fab 226 SMART SM00862 145 220 1.1E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_2418 af51fd94a2cd98cf92b00bdd766d3fab 226 Gene3D G3DSA:3.40.50.2300 1 121 3.0E-38 T 14-10-2018 Tharo_2418 af51fd94a2cd98cf92b00bdd766d3fab 226 Gene3D G3DSA:1.10.10.10 122 225 1.9E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2418 af51fd94a2cd98cf92b00bdd766d3fab 226 SUPERFAMILY SSF52172 1 174 1.16E-39 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_2418 af51fd94a2cd98cf92b00bdd766d3fab 226 SMART SM00448 1 112 3.8E-40 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2418 af51fd94a2cd98cf92b00bdd766d3fab 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 220 1.3E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_2418 af51fd94a2cd98cf92b00bdd766d3fab 226 Pfam PF00072 Response regulator receiver domain 3 112 1.7E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2418 af51fd94a2cd98cf92b00bdd766d3fab 226 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 220 3.8E-107 T 14-10-2018 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 Tharo_2540 6baf8ee4d48216a1228d9fdef5627902 234 SUPERFAMILY SSF46785 13 82 8.83E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_2540 6baf8ee4d48216a1228d9fdef5627902 234 SMART SM00895 88 213 7.9E-14 T 14-10-2018 IPR011711 GntR, C-terminal Tharo_2540 6baf8ee4d48216a1228d9fdef5627902 234 Gene3D G3DSA:1.20.120.530 82 223 9.2E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Tharo_2540 6baf8ee4d48216a1228d9fdef5627902 234 SMART SM00345 21 78 8.4E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_2540 6baf8ee4d48216a1228d9fdef5627902 234 SUPERFAMILY SSF48008 84 215 1.2E-23 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Tharo_2540 6baf8ee4d48216a1228d9fdef5627902 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 3.2E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_2540 6baf8ee4d48216a1228d9fdef5627902 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 3.2E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_2540 6baf8ee4d48216a1228d9fdef5627902 234 Pfam PF07729 FCD domain 88 211 3.2E-20 T 14-10-2018 IPR011711 GntR, C-terminal Tharo_2540 6baf8ee4d48216a1228d9fdef5627902 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 74 3.1E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_2540 6baf8ee4d48216a1228d9fdef5627902 234 Gene3D G3DSA:1.10.10.10 15 80 2.1E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1327 7872ef51bbd47243f8b5e3c6632c51a1 279 Gene3D G3DSA:3.20.20.70 2 278 2.6E-102 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_1327 7872ef51bbd47243f8b5e3c6632c51a1 279 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 13 270 2.5E-122 T 14-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 Tharo_1327 7872ef51bbd47243f8b5e3c6632c51a1 279 Pfam PF00793 DAHP synthetase I family 5 270 1.2E-64 T 14-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 Tharo_1327 7872ef51bbd47243f8b5e3c6632c51a1 279 SUPERFAMILY SSF51569 2 272 8.24E-104 T 14-10-2018 Tharo_1327 7872ef51bbd47243f8b5e3c6632c51a1 279 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 8 272 51.698 T 14-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 Tharo_1610 0c8d4acbf3f362f9d7dc079dd6c72ba1 324 Pfam PF03888 MucB/RseB N-terminal domain 27 202 5.1E-60 T 14-10-2018 IPR033434 MucB/RseB, N-terminal Tharo_1610 0c8d4acbf3f362f9d7dc079dd6c72ba1 324 Pfam PF17188 MucB/RseB C-terminal domain 223 320 1.4E-19 T 14-10-2018 IPR033436 MucB/RseB, C-terminal Tharo_1610 0c8d4acbf3f362f9d7dc079dd6c72ba1 324 Gene3D G3DSA:3.30.200.100 224 323 9.4E-15 T 14-10-2018 IPR038484 MucB/RseB, C-terminal domain superfamily Tharo_1610 0c8d4acbf3f362f9d7dc079dd6c72ba1 324 PIRSF PIRSF005427 1 324 7.1E-89 T 14-10-2018 IPR005588 MucB/RseB Tharo_1610 0c8d4acbf3f362f9d7dc079dd6c72ba1 324 Gene3D G3DSA:2.50.20.10 27 206 7.8E-56 T 14-10-2018 Tharo_1228 04befa4e3e26723461269579000dd626 101 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 48 67 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 Tharo_1228 04befa4e3e26723461269579000dd626 101 PRINTS PR01727 Prokaryotic integration host factor signature 76 90 1.5E-14 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Tharo_1228 04befa4e3e26723461269579000dd626 101 PRINTS PR01727 Prokaryotic integration host factor signature 60 73 1.5E-14 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Tharo_1228 04befa4e3e26723461269579000dd626 101 PRINTS PR01727 Prokaryotic integration host factor signature 42 57 1.5E-14 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Tharo_1228 04befa4e3e26723461269579000dd626 101 SUPERFAMILY SSF47729 3 94 2.94E-31 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Tharo_1228 04befa4e3e26723461269579000dd626 101 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 1 97 30.451 T 14-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 Tharo_1228 04befa4e3e26723461269579000dd626 101 Gene3D G3DSA:4.10.520.10 1 98 1.8E-36 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Tharo_1228 04befa4e3e26723461269579000dd626 101 SMART SM00411 3 92 2.9E-41 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Tharo_1228 04befa4e3e26723461269579000dd626 101 Pfam PF00216 Bacterial DNA-binding protein 3 91 5.5E-30 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Tharo_1228 04befa4e3e26723461269579000dd626 101 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 2 95 4.8E-45 T 14-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 Tharo_1964 6bd9b7982eb62bc422d0ae688c683f7c 561 Pfam PF00501 AMP-binding enzyme 30 450 2.9E-94 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Tharo_1964 6bd9b7982eb62bc422d0ae688c683f7c 561 Pfam PF13193 AMP-binding enzyme C-terminal domain 459 533 1.0E-18 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Tharo_1964 6bd9b7982eb62bc422d0ae688c683f7c 561 SUPERFAMILY SSF56801 19 546 5.1E-143 T 14-10-2018 Tharo_1964 6bd9b7982eb62bc422d0ae688c683f7c 561 Gene3D G3DSA:3.30.300.310 446 549 6.3E-33 T 14-10-2018 Tharo_1964 6bd9b7982eb62bc422d0ae688c683f7c 561 Gene3D G3DSA:3.40.50.12780 12 445 1.0E-106 T 14-10-2018 Tharo_1964 6bd9b7982eb62bc422d0ae688c683f7c 561 ProSitePatterns PS00455 Putative AMP-binding domain signature. 193 204 - T 14-10-2018 IPR020845 AMP-binding, conserved site Tharo_1462 4968275c824764de11bb2b3a7ebcc3f7 224 Gene3D G3DSA:3.40.50.150 22 220 4.8E-31 T 14-10-2018 Tharo_1462 4968275c824764de11bb2b3a7ebcc3f7 224 SUPERFAMILY SSF53335 53 216 6.35E-17 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_1462 4968275c824764de11bb2b3a7ebcc3f7 224 Pfam PF02390 Putative methyltransferase 55 216 1.5E-13 T 14-10-2018 Tharo_3184 1cf887dabf8e5d58cfa5730974c7e3c7 241 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 47 219 5.0E-42 T 14-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG Tharo_3184 1cf887dabf8e5d58cfa5730974c7e3c7 241 Gene3D G3DSA:3.40.50.450 24 223 3.0E-63 T 14-10-2018 Tharo_3184 1cf887dabf8e5d58cfa5730974c7e3c7 241 Pfam PF03641 Possible lysine decarboxylase 89 219 9.1E-32 T 14-10-2018 IPR031100 LOG family Tharo_3184 1cf887dabf8e5d58cfa5730974c7e3c7 241 SUPERFAMILY SSF102405 20 220 8.09E-61 T 14-10-2018 Tharo_2605 ffaf6b4db7f1678499eb42e81f4fbcfb 213 Gene3D G3DSA:1.10.150.240 12 78 2.9E-44 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 Tharo_2605 ffaf6b4db7f1678499eb42e81f4fbcfb 213 SUPERFAMILY SSF56784 1 209 6.7E-41 T 14-10-2018 IPR036412 HAD-like superfamily Tharo_2605 ffaf6b4db7f1678499eb42e81f4fbcfb 213 Gene3D G3DSA:3.40.50.1000 1 189 2.9E-44 T 14-10-2018 IPR023214 HAD superfamily Tharo_2605 ffaf6b4db7f1678499eb42e81f4fbcfb 213 Pfam PF13419 Haloacid dehalogenase-like hydrolase 1 176 2.6E-26 T 14-10-2018 Tharo_1812 66f67479ef4d4ab5e8f8931fa7ed9f2a 296 Pfam PF12833 Helix-turn-helix domain 209 287 2.3E-18 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Tharo_1812 66f67479ef4d4ab5e8f8931fa7ed9f2a 296 Gene3D G3DSA:1.10.10.60 186 292 6.4E-21 T 14-10-2018 Tharo_1812 66f67479ef4d4ab5e8f8931fa7ed9f2a 296 SMART SM00342 202 286 1.6E-17 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Tharo_1812 66f67479ef4d4ab5e8f8931fa7ed9f2a 296 SUPERFAMILY SSF46689 243 287 1.25E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_1812 66f67479ef4d4ab5e8f8931fa7ed9f2a 296 Pfam PF02311 AraC-like ligand binding domain 36 147 3.9E-6 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 Tharo_1812 66f67479ef4d4ab5e8f8931fa7ed9f2a 296 SUPERFAMILY SSF51215 36 171 8.11E-9 T 14-10-2018 IPR037923 Transcription regulator HTH-like Tharo_1812 66f67479ef4d4ab5e8f8931fa7ed9f2a 296 Gene3D G3DSA:2.60.120.10 28 101 6.1E-6 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Tharo_2317 87224cd1ff82044c269e9a727b3d7d16 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 3.3E-24 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2317 87224cd1ff82044c269e9a727b3d7d16 55 Pfam PF00471 Ribosomal protein L33 7 53 3.0E-18 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2317 87224cd1ff82044c269e9a727b3d7d16 55 Gene3D G3DSA:2.20.28.120 1 55 1.2E-29 T 14-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2317 87224cd1ff82044c269e9a727b3d7d16 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 53 14.518 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2317 87224cd1ff82044c269e9a727b3d7d16 55 SUPERFAMILY SSF57829 1 53 7.94E-20 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 Tharo_2317 87224cd1ff82044c269e9a727b3d7d16 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 14-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_1223 84ada452ddd5c7419606950eb1fa77d7 135 SUPERFAMILY SSF55200 48 133 2.22E-34 T 14-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 Tharo_1223 84ada452ddd5c7419606950eb1fa77d7 135 SUPERFAMILY SSF54364 1 41 8.76E-17 T 14-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 Tharo_1223 84ada452ddd5c7419606950eb1fa77d7 135 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 1 133 4.5E-56 T 14-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 Tharo_1223 84ada452ddd5c7419606950eb1fa77d7 135 Gene3D G3DSA:3.30.110.10 40 135 2.2E-38 T 14-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 Tharo_1223 84ada452ddd5c7419606950eb1fa77d7 135 ProSitePatterns PS00938 Initiation factor 3 signature. 22 35 - T 14-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 Tharo_1223 84ada452ddd5c7419606950eb1fa77d7 135 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 1 40 2.7E-18 T 14-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 Tharo_1223 84ada452ddd5c7419606950eb1fa77d7 135 Gene3D G3DSA:3.10.20.80 1 39 5.2E-19 T 14-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 Tharo_1223 84ada452ddd5c7419606950eb1fa77d7 135 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 47 132 4.3E-39 T 14-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 Tharo_2586 49a323b3f19e3cb9c7c026f9d37f04b4 374 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 6 139 3.6E-34 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Tharo_2586 49a323b3f19e3cb9c7c026f9d37f04b4 374 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 14-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 Tharo_2586 49a323b3f19e3cb9c7c026f9d37f04b4 374 SMART SM01002 148 310 4.2E-77 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Tharo_2586 49a323b3f19e3cb9c7c026f9d37f04b4 374 SMART SM01003 6 139 1.4E-55 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Tharo_2586 49a323b3f19e3cb9c7c026f9d37f04b4 374 Gene3D G3DSA:3.40.50.720 139 317 5.1E-129 T 14-10-2018 Tharo_2586 49a323b3f19e3cb9c7c026f9d37f04b4 374 SUPERFAMILY SSF52283 4 170 2.89E-42 T 14-10-2018 Tharo_2586 49a323b3f19e3cb9c7c026f9d37f04b4 374 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 144 365 5.2E-69 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Tharo_2586 49a323b3f19e3cb9c7c026f9d37f04b4 374 Gene3D G3DSA:3.40.50.720 5 362 5.1E-129 T 14-10-2018 Tharo_2586 49a323b3f19e3cb9c7c026f9d37f04b4 374 SUPERFAMILY SSF51735 139 316 9.22E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_2449 e9c05ea113b096976f0e6254e139b976 232 Gene3D G3DSA:3.90.550.10 4 231 1.2E-54 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_2449 e9c05ea113b096976f0e6254e139b976 232 Pfam PF00483 Nucleotidyl transferase 6 221 1.8E-22 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Tharo_2449 e9c05ea113b096976f0e6254e139b976 232 SUPERFAMILY SSF53448 5 227 4.28E-54 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_1434 287f769320e2b723b6d6f2da539de5d5 507 Pfam PF13247 4Fe-4S dicluster domain 175 271 8.5E-38 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_1434 287f769320e2b723b6d6f2da539de5d5 507 Gene3D G3DSA:3.30.70.20 1 301 8.8E-102 T 14-10-2018 Tharo_1434 287f769320e2b723b6d6f2da539de5d5 507 SUPERFAMILY SSF54862 1 499 7.22E-181 T 14-10-2018 Tharo_1434 287f769320e2b723b6d6f2da539de5d5 507 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 358 435 6.7E-28 T 14-10-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 Tharo_1434 287f769320e2b723b6d6f2da539de5d5 507 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 489 1.6E-293 T 14-10-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 Tharo_1434 287f769320e2b723b6d6f2da539de5d5 507 Gene3D G3DSA:1.10.3650.10 358 434 2.2E-28 T 14-10-2018 IPR038262 Nitrate reductase beta, C-terminal domain superfamily KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 Tharo_3102 db23ddf208bbbd74765928cab71b24ce 85 Pfam PF04380 Membrane fusogenic activity 1 75 2.5E-27 T 14-10-2018 IPR007475 Membrane fusogenic activity Tharo_0421 d5ff84aec4d3c8bf8cc5f348ec55c90f 222 SUPERFAMILY SSF55811 90 215 4.6E-17 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Tharo_0421 d5ff84aec4d3c8bf8cc5f348ec55c90f 222 Pfam PF00293 NUDIX domain 93 197 2.3E-11 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Tharo_0421 d5ff84aec4d3c8bf8cc5f348ec55c90f 222 Gene3D G3DSA:3.90.79.10 90 212 7.5E-14 T 14-10-2018 Tharo_2805 43967be894b535a560cae54947fde113 472 ProSitePatterns PS00543 HlyD family secretion proteins signature. 436 458 - T 14-10-2018 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 Tharo_2805 43967be894b535a560cae54947fde113 472 Pfam PF13437 HlyD family secretion protein 327 428 2.0E-17 T 14-10-2018 Tharo_2805 43967be894b535a560cae54947fde113 472 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 436 451 3.6E-44 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_2805 43967be894b535a560cae54947fde113 472 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 112 132 3.6E-44 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_2805 43967be894b535a560cae54947fde113 472 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 70 93 3.6E-44 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_2805 43967be894b535a560cae54947fde113 472 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 396 419 3.6E-44 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_2805 43967be894b535a560cae54947fde113 472 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 372 396 3.6E-44 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_2805 43967be894b535a560cae54947fde113 472 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 339 360 3.6E-44 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_2805 43967be894b535a560cae54947fde113 472 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 451 471 3.6E-44 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_2805 43967be894b535a560cae54947fde113 472 Gene3D G3DSA:2.40.50.100 99 133 2.2E-9 T 14-10-2018 Tharo_2805 43967be894b535a560cae54947fde113 472 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 62 472 3.5E-116 T 14-10-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 Tharo_2805 43967be894b535a560cae54947fde113 472 Pfam PF13533 Biotin-lipoyl like 102 138 7.0E-7 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain Tharo_2805 43967be894b535a560cae54947fde113 472 SUPERFAMILY SSF111369 92 166 1.06E-7 T 14-10-2018 Tharo_2805 43967be894b535a560cae54947fde113 472 Gene3D G3DSA:2.40.30.170 88 98 2.2E-9 T 14-10-2018 Tharo_2805 43967be894b535a560cae54947fde113 472 Gene3D G3DSA:1.10.287.470 134 159 2.2E-9 T 14-10-2018 Tharo_1312 b9c78409039eca3c94ae209f44370378 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 5.1E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1312 b9c78409039eca3c94ae209f44370378 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 218 5.1E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1312 b9c78409039eca3c94ae209f44370378 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 5.1E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1312 b9c78409039eca3c94ae209f44370378 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 5.1E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1312 b9c78409039eca3c94ae209f44370378 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 5.1E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1312 b9c78409039eca3c94ae209f44370378 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 5.1E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1312 b9c78409039eca3c94ae209f44370378 236 Gene3D G3DSA:3.40.50.720 3 235 4.4E-72 T 14-10-2018 Tharo_1312 b9c78409039eca3c94ae209f44370378 236 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 233 1.2E-54 T 14-10-2018 Tharo_1312 b9c78409039eca3c94ae209f44370378 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 6.1E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1312 b9c78409039eca3c94ae209f44370378 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 6.1E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1312 b9c78409039eca3c94ae209f44370378 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 6.1E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1312 b9c78409039eca3c94ae209f44370378 236 SUPERFAMILY SSF51735 9 235 3.53E-72 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1312 b9c78409039eca3c94ae209f44370378 236 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 175 1.8E-5 T 14-10-2018 Tharo_1312 b9c78409039eca3c94ae209f44370378 236 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Tharo_1871 f5767aab7f284c1d1eff71496eefafbf 256 Gene3D G3DSA:3.90.226.10 2 197 3.6E-69 T 14-10-2018 Tharo_1871 f5767aab7f284c1d1eff71496eefafbf 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 255 1.2E-75 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Tharo_1871 f5767aab7f284c1d1eff71496eefafbf 256 Gene3D G3DSA:1.10.12.10 199 255 5.3E-23 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal Tharo_1871 f5767aab7f284c1d1eff71496eefafbf 256 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 97 117 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 Tharo_1871 f5767aab7f284c1d1eff71496eefafbf 256 SUPERFAMILY SSF52096 2 255 3.22E-89 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_1594 2c3205aa33c9bc8f09051a60fe9c3d14 319 SUPERFAMILY SSF55120 89 312 2.08E-67 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_1594 2c3205aa33c9bc8f09051a60fe9c3d14 319 Gene3D G3DSA:3.30.2350.10 92 315 6.8E-78 T 14-10-2018 Tharo_1594 2c3205aa33c9bc8f09051a60fe9c3d14 319 Gene3D G3DSA:3.10.290.10 11 75 4.8E-15 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Tharo_1594 2c3205aa33c9bc8f09051a60fe9c3d14 319 Pfam PF00849 RNA pseudouridylate synthase 100 248 1.0E-28 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_1594 2c3205aa33c9bc8f09051a60fe9c3d14 319 Pfam PF01479 S4 domain 23 69 3.2E-8 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_1594 2c3205aa33c9bc8f09051a60fe9c3d14 319 SMART SM00363 23 84 3.3E-5 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_1594 2c3205aa33c9bc8f09051a60fe9c3d14 319 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 138 152 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_1594 2c3205aa33c9bc8f09051a60fe9c3d14 319 SUPERFAMILY SSF55174 22 73 1.91E-8 T 14-10-2018 Tharo_1594 2c3205aa33c9bc8f09051a60fe9c3d14 319 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 18 311 3.3E-83 T 14-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_1054 d5b63489cd789601302af64398c79464 403 Gene3D G3DSA:1.20.1720.10 14 392 4.7E-84 T 14-10-2018 Tharo_1054 d5b63489cd789601302af64398c79464 403 SUPERFAMILY SSF103473 7 397 1.23E-56 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_1054 d5b63489cd789601302af64398c79464 403 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 18 388 1.1E-60 T 14-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 Tharo_1054 d5b63489cd789601302af64398c79464 403 Pfam PF07690 Major Facilitator Superfamily 16 360 3.0E-41 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_1349 ea3a35c8c14cadc1d60be2eb8a3e2d25 378 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 212 226 - T 14-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 Tharo_1349 ea3a35c8c14cadc1d60be2eb8a3e2d25 378 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 178 337 9.2E-55 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 Tharo_1349 ea3a35c8c14cadc1d60be2eb8a3e2d25 378 SMART SM00363 111 169 1.4E-12 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_1349 ea3a35c8c14cadc1d60be2eb8a3e2d25 378 Gene3D G3DSA:3.30.70.580 175 334 9.1E-53 T 14-10-2018 Tharo_1349 ea3a35c8c14cadc1d60be2eb8a3e2d25 378 Pfam PF00849 RNA pseudouridylate synthase 174 307 2.1E-16 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_1349 ea3a35c8c14cadc1d60be2eb8a3e2d25 378 SUPERFAMILY SSF55120 173 338 8.39E-43 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_1349 ea3a35c8c14cadc1d60be2eb8a3e2d25 378 Gene3D G3DSA:3.30.70.1560 236 326 9.1E-53 T 14-10-2018 Tharo_1349 ea3a35c8c14cadc1d60be2eb8a3e2d25 378 SUPERFAMILY SSF55174 111 200 1.91E-18 T 14-10-2018 Tharo_1349 ea3a35c8c14cadc1d60be2eb8a3e2d25 378 Pfam PF01479 S4 domain 111 156 4.1E-12 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_1349 ea3a35c8c14cadc1d60be2eb8a3e2d25 378 Gene3D G3DSA:3.10.290.10 107 164 5.2E-21 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Tharo_1448 a08a87fc6773430e07f1a8dc6c40d411 796 Pfam PF08497 Radical SAM N-terminal 62 427 3.7E-136 T 14-10-2018 IPR013704 Uncharacterised protein family UPF0313, N-terminal Tharo_1448 a08a87fc6773430e07f1a8dc6c40d411 796 Pfam PF04055 Radical SAM superfamily 428 633 9.9E-18 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_1448 a08a87fc6773430e07f1a8dc6c40d411 796 Gene3D G3DSA:3.80.30.20 424 683 3.3E-16 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Tharo_1448 a08a87fc6773430e07f1a8dc6c40d411 796 SMART SM00729 424 677 3.8E-9 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Tharo_1448 a08a87fc6773430e07f1a8dc6c40d411 796 SUPERFAMILY SSF102114 426 661 5.1E-16 T 14-10-2018 Tharo_1448 a08a87fc6773430e07f1a8dc6c40d411 796 TIGRFAM TIGR03904 SAM_YgiQ: uncharacterized radical SAM protein YgiQ 62 692 4.6E-252 T 14-10-2018 IPR022946 Uncharacterised protein family UPF0313 Tharo_1448 a08a87fc6773430e07f1a8dc6c40d411 796 Hamap MF_01251 UPF0313 protein YgiQ [ygiQ]. 62 694 48.596 T 14-10-2018 IPR022946 Uncharacterised protein family UPF0313 Tharo_1448 a08a87fc6773430e07f1a8dc6c40d411 796 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 428 448 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 Tharo_1448 a08a87fc6773430e07f1a8dc6c40d411 796 Pfam PF11842 Domain of unknown function (DUF3362) 642 761 2.3E-42 T 14-10-2018 IPR024560 Uncharacterised protein family UPF0313, C-terminal Tharo_0642 1fcd4150de8a55d6c92ff7d8c34cd8e4 113 SUPERFAMILY SSF101386 6 95 2.43E-25 T 14-10-2018 Tharo_0642 1fcd4150de8a55d6c92ff7d8c34cd8e4 113 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 8 93 4.6E-17 T 14-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 Tharo_0642 1fcd4150de8a55d6c92ff7d8c34cd8e4 113 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 4 90 20.658 T 14-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 Tharo_0642 1fcd4150de8a55d6c92ff7d8c34cd8e4 113 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 7 89 9.7E-32 T 14-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 Tharo_0642 1fcd4150de8a55d6c92ff7d8c34cd8e4 113 Gene3D G3DSA:1.10.287.1080 3 95 1.3E-29 T 14-10-2018 Tharo_3132 39404f8ab7adff0fd9037fa98e7c5940 483 SUPERFAMILY SSF53098 180 339 1.39E-24 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_3132 39404f8ab7adff0fd9037fa98e7c5940 483 Pfam PF00665 Integrase core domain 179 293 5.7E-17 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Tharo_3132 39404f8ab7adff0fd9037fa98e7c5940 483 Gene3D G3DSA:3.30.420.10 165 341 6.0E-15 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_1585 39404f8ab7adff0fd9037fa98e7c5940 483 SUPERFAMILY SSF53098 180 339 1.39E-24 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_1585 39404f8ab7adff0fd9037fa98e7c5940 483 Pfam PF00665 Integrase core domain 179 293 5.7E-17 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Tharo_1585 39404f8ab7adff0fd9037fa98e7c5940 483 Gene3D G3DSA:3.30.420.10 165 341 6.0E-15 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_1536 39404f8ab7adff0fd9037fa98e7c5940 483 SUPERFAMILY SSF53098 180 339 1.39E-24 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_1536 39404f8ab7adff0fd9037fa98e7c5940 483 Pfam PF00665 Integrase core domain 179 293 5.7E-17 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Tharo_1536 39404f8ab7adff0fd9037fa98e7c5940 483 Gene3D G3DSA:3.30.420.10 165 341 6.0E-15 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_1799 3a58945ce324dec72ab84e6f92de536d 279 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 71 242 6.8E-36 T 14-10-2018 Tharo_1799 3a58945ce324dec72ab84e6f92de536d 279 SUPERFAMILY SSF56784 65 273 1.9E-51 T 14-10-2018 IPR036412 HAD-like superfamily Tharo_1799 3a58945ce324dec72ab84e6f92de536d 279 Pfam PF13284 Domain of unknown function (DUF4072) 3 43 9.7E-7 T 14-10-2018 IPR025138 Domain of unknown function DUF4072 Tharo_1799 3a58945ce324dec72ab84e6f92de536d 279 Pfam PF12710 haloacid dehalogenase-like hydrolase 73 241 2.2E-26 T 14-10-2018 Tharo_1799 3a58945ce324dec72ab84e6f92de536d 279 Gene3D G3DSA:3.40.50.1000 9 278 7.5E-76 T 14-10-2018 IPR023214 HAD superfamily Tharo_1799 3a58945ce324dec72ab84e6f92de536d 279 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 69 274 2.9E-67 T 14-10-2018 Tharo_1799 3a58945ce324dec72ab84e6f92de536d 279 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 230 249 3.2E-5 T 14-10-2018 Tharo_1799 3a58945ce324dec72ab84e6f92de536d 279 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 156 166 3.2E-5 T 14-10-2018 Tharo_2493 902064ad828e15eb0aca22ed8979d2ae 450 Gene3D G3DSA:3.30.460.10 21 176 1.2E-56 T 14-10-2018 Tharo_2493 902064ad828e15eb0aca22ed8979d2ae 450 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 207 268 1.7E-18 T 14-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 Tharo_2493 902064ad828e15eb0aca22ed8979d2ae 450 Gene3D G3DSA:1.10.3090.10 178 422 1.3E-80 T 14-10-2018 Tharo_2493 902064ad828e15eb0aca22ed8979d2ae 450 SUPERFAMILY SSF81891 178 410 1.96E-50 T 14-10-2018 Tharo_2493 902064ad828e15eb0aca22ed8979d2ae 450 Pfam PF12626 Polymerase A arginine-rich C-terminus 321 437 1.0E-40 T 14-10-2018 IPR025866 Polymerase A arginine-rich C-terminal domain Tharo_2493 902064ad828e15eb0aca22ed8979d2ae 450 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 18 439 35.36 T 14-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 Tharo_2493 902064ad828e15eb0aca22ed8979d2ae 450 SUPERFAMILY SSF81301 27 177 1.85E-39 T 14-10-2018 Tharo_2493 902064ad828e15eb0aca22ed8979d2ae 450 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 24 437 1.2E-144 T 14-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 Tharo_2493 902064ad828e15eb0aca22ed8979d2ae 450 Pfam PF01743 Poly A polymerase head domain 54 180 2.9E-34 T 14-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 Tharo_3057 5793f607af221a9e0bdcb8f68e1d2ff4 101 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 7 91 1.0E-30 T 14-10-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 Tharo_2717 7a82b3d713fd2e221f32390c98cdb37c 138 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 14-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2717 7a82b3d713fd2e221f32390c98cdb37c 138 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 14-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2717 7a82b3d713fd2e221f32390c98cdb37c 138 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 7.6E-60 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2717 7a82b3d713fd2e221f32390c98cdb37c 138 SUPERFAMILY SSF54686 1 135 1.57E-53 T 14-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 Tharo_2717 7a82b3d713fd2e221f32390c98cdb37c 138 PRINTS PR00060 Ribosomal protein L16 signature 58 87 8.2E-41 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2717 7a82b3d713fd2e221f32390c98cdb37c 138 PRINTS PR00060 Ribosomal protein L16 signature 24 36 8.2E-41 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2717 7a82b3d713fd2e221f32390c98cdb37c 138 PRINTS PR00060 Ribosomal protein L16 signature 42 53 8.2E-41 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2717 7a82b3d713fd2e221f32390c98cdb37c 138 PRINTS PR00060 Ribosomal protein L16 signature 88 117 8.2E-41 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2717 7a82b3d713fd2e221f32390c98cdb37c 138 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.848 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2717 7a82b3d713fd2e221f32390c98cdb37c 138 Gene3D G3DSA:3.90.1170.10 1 137 1.3E-55 T 14-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 Tharo_2717 7a82b3d713fd2e221f32390c98cdb37c 138 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 3.9E-49 T 14-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 Tharo_2070 b62894d7c21742f696febcbb605a299f 245 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 1 245 31.645 T 14-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 Tharo_2070 b62894d7c21742f696febcbb605a299f 245 SUPERFAMILY SSF53167 1 242 2.75E-77 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 Tharo_2070 b62894d7c21742f696febcbb605a299f 245 Gene3D G3DSA:3.40.50.1580 1 245 2.5E-78 T 14-10-2018 Tharo_2070 b62894d7c21742f696febcbb605a299f 245 Pfam PF01048 Phosphorylase superfamily 2 239 3.0E-44 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Tharo_1341 9b3c9d253a3ed289fc7d658a48bf0ec3 69 Pfam PF00313 'Cold-shock' DNA-binding domain 5 67 4.4E-30 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Tharo_1341 9b3c9d253a3ed289fc7d658a48bf0ec3 69 SMART SM00357 5 69 2.6E-30 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 Tharo_1341 9b3c9d253a3ed289fc7d658a48bf0ec3 69 SUPERFAMILY SSF50249 3 68 4.07E-25 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_1341 9b3c9d253a3ed289fc7d658a48bf0ec3 69 PRINTS PR00050 Cold shock protein signature 27 36 7.4E-16 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Tharo_1341 9b3c9d253a3ed289fc7d658a48bf0ec3 69 PRINTS PR00050 Cold shock protein signature 6 21 7.4E-16 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Tharo_1341 9b3c9d253a3ed289fc7d658a48bf0ec3 69 PRINTS PR00050 Cold shock protein signature 42 60 7.4E-16 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Tharo_1341 9b3c9d253a3ed289fc7d658a48bf0ec3 69 Gene3D G3DSA:2.40.50.140 4 67 9.2E-30 T 14-10-2018 Tharo_1341 9b3c9d253a3ed289fc7d658a48bf0ec3 69 PIRSF PIRSF002599 1 69 1.4E-24 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 Tharo_1341 9b3c9d253a3ed289fc7d658a48bf0ec3 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 17 36 - T 14-10-2018 IPR019844 Cold-shock conserved site Tharo_2758 19342034ff243ff3a4faa06c70d58578 279 SMART SM00858 36 98 4.1E-12 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 Tharo_2758 19342034ff243ff3a4faa06c70d58578 279 Pfam PF08666 SAF domain 37 97 7.3E-9 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 Tharo_2758 19342034ff243ff3a4faa06c70d58578 279 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 104 213 1.9E-31 T 14-10-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain Tharo_2758 19342034ff243ff3a4faa06c70d58578 279 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 7 275 7.2E-82 T 14-10-2018 IPR017592 Pilus assembly, Flp-type CpaB Tharo_1053 fb66ec5021c9933d5bc3c4a90e120ff6 93 SUPERFAMILY SSF143011 1 82 1.06E-18 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_1053 fb66ec5021c9933d5bc3c4a90e120ff6 93 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 7 81 2.4E-7 T 14-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Tharo_1053 fb66ec5021c9933d5bc3c4a90e120ff6 93 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 9 84 6.5E-11 T 14-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Tharo_1053 fb66ec5021c9933d5bc3c4a90e120ff6 93 Gene3D G3DSA:3.30.2310.20 1 93 1.4E-24 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_2324 2bdb0014cc4a46461d053ece94cce1af 254 Gene3D G3DSA:1.10.10.10 134 244 1.6E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2324 2bdb0014cc4a46461d053ece94cce1af 254 Gene3D G3DSA:3.40.50.2300 1 133 1.3E-38 T 14-10-2018 Tharo_2324 2bdb0014cc4a46461d053ece94cce1af 254 Pfam PF00072 Response regulator receiver domain 7 120 5.0E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2324 2bdb0014cc4a46461d053ece94cce1af 254 SMART SM00862 163 239 8.3E-19 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_2324 2bdb0014cc4a46461d053ece94cce1af 254 SMART SM00448 5 119 3.9E-42 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2324 2bdb0014cc4a46461d053ece94cce1af 254 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 239 4.1E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_2324 2bdb0014cc4a46461d053ece94cce1af 254 SUPERFAMILY SSF46894 139 240 1.96E-23 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_2324 2bdb0014cc4a46461d053ece94cce1af 254 SUPERFAMILY SSF52172 4 133 7.26E-43 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_0277 c287c73e18520b44b6c414afb20fff64 105 SUPERFAMILY SSF89447 3 49 5.93E-10 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily Tharo_0277 c287c73e18520b44b6c414afb20fff64 105 Pfam PF15937 prlF antitoxin for toxin YhaV_toxin 8 75 1.2E-15 T 14-10-2018 IPR031848 PrlF antitoxin GO:0001558|GO:0003700|GO:0097351 Tharo_0277 c287c73e18520b44b6c414afb20fff64 105 SMART SM00966 8 53 3.6E-8 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Tharo_0277 c287c73e18520b44b6c414afb20fff64 105 ProDom PD030562 SUPPRESSOR HTRA PROTEASE TRANSCRIPTIONAL REGULATOR HTAR SOHA ABRB YDCA BLL1688 8 70 2.0E-7 T 14-10-2018 Tharo_0277 c287c73e18520b44b6c414afb20fff64 105 Gene3D G3DSA:2.10.260.10 3 46 4.1E-11 T 14-10-2018 Tharo_3021 1b8ef609bd0c80ab531b4e9830b541d6 297 Pfam PF05107 CRISPR-associated protein Cas7 6 283 4.2E-111 T 14-10-2018 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C Tharo_3021 1b8ef609bd0c80ab531b4e9830b541d6 297 TIGRFAM TIGR01595 cas_CT1132: CRISPR-associated protein, CT1132 family 4 283 9.5E-87 T 14-10-2018 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C Tharo_3021 1b8ef609bd0c80ab531b4e9830b541d6 297 TIGRFAM TIGR02589 cas_Csd2: CRISPR-associated protein Cas7/Csd2, subtype I-C/DVULG 7 295 3.3E-125 T 14-10-2018 IPR013418 CRISPR-associated protein Csd2 Tharo_0927 ff32494440f982ec83f22ddd8f5c21e2 287 Pfam PF08478 POTRA domain, FtsQ-type 67 136 1.5E-16 T 14-10-2018 IPR013685 POTRA domain, FtsQ-type Tharo_0927 ff32494440f982ec83f22ddd8f5c21e2 287 Pfam PF03799 Cell division protein FtsQ 140 259 6.1E-24 T 14-10-2018 IPR005548 Cell division protein FtsQ/DivIB Tharo_0927 ff32494440f982ec83f22ddd8f5c21e2 287 Gene3D G3DSA:3.10.20.310 66 136 3.8E-18 T 14-10-2018 Tharo_0927 ff32494440f982ec83f22ddd8f5c21e2 287 Gene3D G3DSA:3.40.50.11690 138 272 3.1E-33 T 14-10-2018 Tharo_0927 ff32494440f982ec83f22ddd8f5c21e2 287 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 37 267 21.184 T 14-10-2018 IPR026579 Cell division protein FtsQ GO:0090529 Tharo_1014 3c71d17f9f4590db1a40f03b82217429 357 SMART SM00448 10 126 1.5E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1014 3c71d17f9f4590db1a40f03b82217429 357 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 10 352 31.814 T 14-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Tharo_1014 3c71d17f9f4590db1a40f03b82217429 357 Pfam PF00072 Response regulator receiver domain 12 113 8.3E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1014 3c71d17f9f4590db1a40f03b82217429 357 Gene3D G3DSA:3.40.50.180 164 351 2.0E-65 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal Tharo_1014 3c71d17f9f4590db1a40f03b82217429 357 SUPERFAMILY SSF52172 8 131 3.42E-29 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1014 3c71d17f9f4590db1a40f03b82217429 357 Gene3D G3DSA:3.40.50.2300 7 141 4.1E-29 T 14-10-2018 Tharo_1014 3c71d17f9f4590db1a40f03b82217429 357 SUPERFAMILY SSF52738 169 351 6.41E-61 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal Tharo_1014 3c71d17f9f4590db1a40f03b82217429 357 PIRSF PIRSF000876 7 356 2.1E-101 T 14-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Tharo_1014 3c71d17f9f4590db1a40f03b82217429 357 Pfam PF01339 CheB methylesterase 171 347 4.3E-58 T 14-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Tharo_1036 f99d2073d966fc7535e2f450c7b178d7 333 PIRSF PIRSF000904 1 333 4.3E-122 T 14-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Tharo_1036 f99d2073d966fc7535e2f450c7b178d7 333 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 5 192 4.0E-62 T 14-10-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Tharo_1036 f99d2073d966fc7535e2f450c7b178d7 333 PIRSF PIRSF500210 1 333 2.9E-122 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Tharo_1036 f99d2073d966fc7535e2f450c7b178d7 333 Gene3D G3DSA:3.30.540.10 1 193 2.7E-69 T 14-10-2018 Tharo_1036 f99d2073d966fc7535e2f450c7b178d7 333 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 28 55 2.3E-69 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Tharo_1036 f99d2073d966fc7535e2f450c7b178d7 333 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 65 91 2.3E-69 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Tharo_1036 f99d2073d966fc7535e2f450c7b178d7 333 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 147 170 2.3E-69 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Tharo_1036 f99d2073d966fc7535e2f450c7b178d7 333 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 306 331 2.3E-69 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Tharo_1036 f99d2073d966fc7535e2f450c7b178d7 333 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 204 231 2.3E-69 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Tharo_1036 f99d2073d966fc7535e2f450c7b178d7 333 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 178 201 2.3E-69 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Tharo_1036 f99d2073d966fc7535e2f450c7b178d7 333 Gene3D G3DSA:3.40.190.80 195 329 4.7E-53 T 14-10-2018 Tharo_1036 f99d2073d966fc7535e2f450c7b178d7 333 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 4 332 45.557 T 14-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Tharo_1036 f99d2073d966fc7535e2f450c7b178d7 333 SUPERFAMILY SSF56655 3 330 5.95E-112 T 14-10-2018 Tharo_0682 3b8864179908bbf5e5f8c8f6fab1e9cf 646 Pfam PF12697 Alpha/beta hydrolase family 365 625 3.0E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_0682 3b8864179908bbf5e5f8c8f6fab1e9cf 646 Gene3D G3DSA:3.40.50.1820 356 618 1.1E-22 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_0682 3b8864179908bbf5e5f8c8f6fab1e9cf 646 SUPERFAMILY SSF53474 358 608 4.09E-23 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_1040 9ca0650685b7ba2fd88769cb85ff0273 188 SUPERFAMILY SSF53271 9 158 3.55E-23 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Tharo_1040 9ca0650685b7ba2fd88769cb85ff0273 188 Gene3D G3DSA:3.40.50.2020 6 186 4.1E-30 T 14-10-2018 Tharo_1040 9ca0650685b7ba2fd88769cb85ff0273 188 Pfam PF00156 Phosphoribosyl transferase domain 18 165 2.1E-21 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Tharo_1895 fb3f93fe9ae95c786f8f17e0cf39ae51 151 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 10 91 4.0E-29 T 14-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 Tharo_1895 fb3f93fe9ae95c786f8f17e0cf39ae51 151 SUPERFAMILY SSF75471 3 93 8.89E-27 T 14-10-2018 IPR035920 YhbY-like superfamily Tharo_1895 fb3f93fe9ae95c786f8f17e0cf39ae51 151 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 4 93 2.4E-23 T 14-10-2018 IPR017924 RNA-binding protein YhbY GO:0003723 Tharo_1895 fb3f93fe9ae95c786f8f17e0cf39ae51 151 SMART SM01103 4 87 5.5E-40 T 14-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 Tharo_1895 fb3f93fe9ae95c786f8f17e0cf39ae51 151 Gene3D G3DSA:3.30.110.60 2 103 1.6E-30 T 14-10-2018 IPR035920 YhbY-like superfamily Tharo_1895 fb3f93fe9ae95c786f8f17e0cf39ae51 151 Pfam PF01985 CRS1 / YhbY (CRM) domain 4 87 3.2E-20 T 14-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 Tharo_1885 f8817d85ed69c0e7653010cd77a649f6 370 Gene3D G3DSA:3.30.450.40 133 365 5.3E-44 T 14-10-2018 IPR029016 GAF-like domain superfamily Tharo_1885 f8817d85ed69c0e7653010cd77a649f6 370 Gene3D G3DSA:3.30.390.60 156 256 5.3E-44 T 14-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily Tharo_1885 f8817d85ed69c0e7653010cd77a649f6 370 SUPERFAMILY SSF55781 101 368 6.87E-62 T 14-10-2018 Tharo_1885 f8817d85ed69c0e7653010cd77a649f6 370 Gene3D G3DSA:1.10.10.10 19 114 5.1E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1885 f8817d85ed69c0e7653010cd77a649f6 370 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 37 102 1.2E-4 T 14-10-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 Tharo_1885 f8817d85ed69c0e7653010cd77a649f6 370 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 33 365 1.0E-98 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 Tharo_1885 f8817d85ed69c0e7653010cd77a649f6 370 Pfam PF01628 HrcA protein C terminal domain 134 352 1.9E-59 T 14-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 Tharo_1885 f8817d85ed69c0e7653010cd77a649f6 370 PIRSF PIRSF005485 29 370 4.8E-112 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 Tharo_1885 f8817d85ed69c0e7653010cd77a649f6 370 SUPERFAMILY SSF46785 32 113 1.05E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1885 f8817d85ed69c0e7653010cd77a649f6 370 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 31 359 28.301 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 Tharo_0826 3552624447b5fa73f0d69ae8ca75246b 172 PIRSF PIRSF016481 1 168 3.1E-40 T 14-10-2018 IPR007446 Pilus assembly protein PilP Tharo_0826 3552624447b5fa73f0d69ae8ca75246b 172 Pfam PF04351 Pilus assembly protein, PilP 23 164 9.5E-42 T 14-10-2018 IPR007446 Pilus assembly protein PilP Tharo_0826 3552624447b5fa73f0d69ae8ca75246b 172 Gene3D G3DSA:2.30.30.830 74 165 1.2E-29 T 14-10-2018 Tharo_1159 50b01b77f1ff6f83b37d4f63a4148315 443 Gene3D G3DSA:2.40.50.140 381 443 2.7E-15 T 14-10-2018 Tharo_1159 50b01b77f1ff6f83b37d4f63a4148315 443 SUPERFAMILY SSF102114 115 377 3.27E-54 T 14-10-2018 Tharo_1159 50b01b77f1ff6f83b37d4f63a4148315 443 Pfam PF04055 Radical SAM superfamily 147 324 2.6E-30 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_1159 50b01b77f1ff6f83b37d4f63a4148315 443 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 145 165 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 Tharo_1159 50b01b77f1ff6f83b37d4f63a4148315 443 Pfam PF00919 Uncharacterized protein family UPF0004 11 102 1.8E-19 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 Tharo_1159 50b01b77f1ff6f83b37d4f63a4148315 443 Gene3D G3DSA:3.80.30.20 139 380 6.8E-73 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Tharo_1159 50b01b77f1ff6f83b37d4f63a4148315 443 SMART SM00729 141 366 4.8E-57 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Tharo_1159 50b01b77f1ff6f83b37d4f63a4148315 443 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 11 438 2.9E-169 T 14-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 Tharo_1159 50b01b77f1ff6f83b37d4f63a4148315 443 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 10 441 60.717 T 14-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 Tharo_1159 50b01b77f1ff6f83b37d4f63a4148315 443 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 12 439 9.6E-102 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 Tharo_1159 50b01b77f1ff6f83b37d4f63a4148315 443 Gene3D G3DSA:3.40.50.12160 11 129 3.1E-26 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily Tharo_1241 07ee62d2db2c8621df6398ba63c4383b 448 SUPERFAMILY SSF53335 61 443 3.03E-77 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_1241 07ee62d2db2c8621df6398ba63c4383b 448 SUPERFAMILY SSF50249 4 58 4.0E-13 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_1241 07ee62d2db2c8621df6398ba63c4383b 448 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 269 443 5.5E-16 T 14-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 Tharo_1241 07ee62d2db2c8621df6398ba63c4383b 448 Gene3D G3DSA:2.40.50.140 2 72 2.6E-25 T 14-10-2018 Tharo_1241 07ee62d2db2c8621df6398ba63c4383b 448 Gene3D G3DSA:3.40.1350.30 120 274 3.2E-102 T 14-10-2018 Tharo_1241 07ee62d2db2c8621df6398ba63c4383b 448 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 9 437 5.3E-93 T 14-10-2018 Tharo_1241 07ee62d2db2c8621df6398ba63c4383b 448 Gene3D G3DSA:3.40.50.150 73 439 3.2E-102 T 14-10-2018 Tharo_1241 07ee62d2db2c8621df6398ba63c4383b 448 Pfam PF01938 TRAM domain 5 51 1.2E-5 T 14-10-2018 IPR002792 TRAM domain Tharo_1241 07ee62d2db2c8621df6398ba63c4383b 448 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 374 405 - T 14-10-2018 IPR030390 RNA methyltransferase TrmA, active site Tharo_1241 07ee62d2db2c8621df6398ba63c4383b 448 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 3 445 67.754 T 14-10-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 Tharo_2550 786fa15f2dcf9a873336df3a0b016a6d 794 Gene3D G3DSA:3.30.365.10 385 775 5.3E-114 T 14-10-2018 Tharo_2550 786fa15f2dcf9a873336df3a0b016a6d 794 Gene3D G3DSA:3.90.1170.50 45 135 4.4E-115 T 14-10-2018 Tharo_2550 786fa15f2dcf9a873336df3a0b016a6d 794 SUPERFAMILY SSF54665 8 154 3.27E-41 T 14-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily Tharo_2550 786fa15f2dcf9a873336df3a0b016a6d 794 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 30 135 1.3E-29 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Tharo_2550 786fa15f2dcf9a873336df3a0b016a6d 794 SMART SM01008 30 135 1.6E-46 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Tharo_2550 786fa15f2dcf9a873336df3a0b016a6d 794 Gene3D G3DSA:3.30.365.10 136 374 4.4E-115 T 14-10-2018 Tharo_2550 786fa15f2dcf9a873336df3a0b016a6d 794 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 168 720 2.0E-150 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Tharo_2550 786fa15f2dcf9a873336df3a0b016a6d 794 Gene3D G3DSA:3.30.365.10 469 636 5.3E-114 T 14-10-2018 Tharo_2550 786fa15f2dcf9a873336df3a0b016a6d 794 SUPERFAMILY SSF56003 127 781 2.75E-178 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 Tharo_2550 786fa15f2dcf9a873336df3a0b016a6d 794 Gene3D G3DSA:3.30.365.10 28 298 4.4E-115 T 14-10-2018 Tharo_1787 07228107d181552b250f2bfe567133b4 270 SUPERFAMILY SSF52540 2 268 5.24E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1787 07228107d181552b250f2bfe567133b4 270 Gene3D G3DSA:3.40.50.300 1 259 5.2E-67 T 14-10-2018 Tharo_1787 07228107d181552b250f2bfe567133b4 270 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 2 267 4.6E-102 T 14-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 Tharo_1787 07228107d181552b250f2bfe567133b4 270 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 225 4.4E-19 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain Tharo_1787 07228107d181552b250f2bfe567133b4 270 PIRSF PIRSF003092 1 270 2.1E-88 T 14-10-2018 IPR025501 ATP binding protein MinD Tharo_0930 26cfcb23c631124ca6ccd7b9e583502c 307 Gene3D G3DSA:3.30.1700.10 128 301 3.0E-67 T 14-10-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 Tharo_0930 26cfcb23c631124ca6ccd7b9e583502c 307 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 279 45.179 T 14-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 Tharo_0930 26cfcb23c631124ca6ccd7b9e583502c 307 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2 292 5.9E-120 T 14-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 Tharo_0930 26cfcb23c631124ca6ccd7b9e583502c 307 SUPERFAMILY SSF54211 133 277 3.03E-52 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_0930 26cfcb23c631124ca6ccd7b9e583502c 307 SUPERFAMILY SSF54211 3 124 3.26E-41 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_0930 26cfcb23c631124ca6ccd7b9e583502c 307 Gene3D G3DSA:3.30.230.20 1 127 2.3E-46 T 14-10-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 Tharo_0930 26cfcb23c631124ca6ccd7b9e583502c 307 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 275 3.0E-105 T 14-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 Tharo_2278 e8466c45ffd4a63d6762b701c16c139e 714 Pfam PF00072 Response regulator receiver domain 8 113 3.2E-8 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2278 e8466c45ffd4a63d6762b701c16c139e 714 SMART SM00448 5 117 1.7E-5 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2278 e8466c45ffd4a63d6762b701c16c139e 714 Gene3D G3DSA:3.40.50.2300 1 139 1.1E-15 T 14-10-2018 Tharo_2278 e8466c45ffd4a63d6762b701c16c139e 714 SUPERFAMILY SSF55785 151 257 6.11E-29 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_2278 e8466c45ffd4a63d6762b701c16c139e 714 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 267 417 4.0E-29 T 14-10-2018 IPR000160 GGDEF domain Tharo_2278 e8466c45ffd4a63d6762b701c16c139e 714 SUPERFAMILY SSF52172 4 140 1.02E-18 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_2278 e8466c45ffd4a63d6762b701c16c139e 714 SMART SM00052 442 688 1.0E-119 T 14-10-2018 IPR001633 EAL domain Tharo_2278 e8466c45ffd4a63d6762b701c16c139e 714 Gene3D G3DSA:3.20.20.450 445 695 1.3E-99 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_2278 e8466c45ffd4a63d6762b701c16c139e 714 SMART SM00091 145 211 1.3E-8 T 14-10-2018 IPR000014 PAS domain Tharo_2278 e8466c45ffd4a63d6762b701c16c139e 714 Gene3D G3DSA:3.30.70.270 269 444 9.3E-50 T 14-10-2018 Tharo_2278 e8466c45ffd4a63d6762b701c16c139e 714 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 143 264 1.7E-20 T 14-10-2018 IPR000014 PAS domain Tharo_2278 e8466c45ffd4a63d6762b701c16c139e 714 SMART SM00086 217 259 9.6E-5 T 14-10-2018 IPR001610 PAC motif Tharo_2278 e8466c45ffd4a63d6762b701c16c139e 714 SUPERFAMILY SSF141868 447 691 2.88E-87 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_2278 e8466c45ffd4a63d6762b701c16c139e 714 Pfam PF13426 PAS domain 156 257 5.3E-14 T 14-10-2018 IPR000014 PAS domain Tharo_2278 e8466c45ffd4a63d6762b701c16c139e 714 Pfam PF00563 EAL domain 448 683 7.8E-74 T 14-10-2018 IPR001633 EAL domain Tharo_2278 e8466c45ffd4a63d6762b701c16c139e 714 SUPERFAMILY SSF55073 275 433 1.8E-38 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_2278 e8466c45ffd4a63d6762b701c16c139e 714 Pfam PF00990 Diguanylate cyclase, GGDEF domain 271 417 5.8E-40 T 14-10-2018 IPR000160 GGDEF domain Tharo_2278 e8466c45ffd4a63d6762b701c16c139e 714 Gene3D G3DSA:3.30.450.20 140 268 2.0E-36 T 14-10-2018 Tharo_2278 e8466c45ffd4a63d6762b701c16c139e 714 SMART SM00267 259 432 3.1E-45 T 14-10-2018 IPR000160 GGDEF domain Tharo_2209 e085c07f50a01dcbb073fe9c2f58c859 375 PIRSF PIRSF000524 18 375 4.7E-44 T 14-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 Tharo_2209 e085c07f50a01dcbb073fe9c2f58c859 375 Gene3D G3DSA:3.40.640.10 39 270 1.2E-123 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_2209 e085c07f50a01dcbb073fe9c2f58c859 375 Gene3D G3DSA:3.90.1150.10 271 370 1.2E-123 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_2209 e085c07f50a01dcbb073fe9c2f58c859 375 SUPERFAMILY SSF53383 10 372 1.71E-76 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_2209 e085c07f50a01dcbb073fe9c2f58c859 375 Pfam PF00266 Aminotransferase class-V 21 297 9.3E-13 T 14-10-2018 IPR000192 Aminotransferase class V domain Tharo_1654 658128221b50c5af7d0764f447f6c059 302 Pfam PF00348 Polyprenyl synthetase 37 266 7.4E-50 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 Tharo_1654 658128221b50c5af7d0764f447f6c059 302 Gene3D G3DSA:1.10.600.10 9 302 5.3E-91 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily Tharo_1654 658128221b50c5af7d0764f447f6c059 302 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 221 233 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site Tharo_1654 658128221b50c5af7d0764f447f6c059 302 SUPERFAMILY SSF48576 9 295 3.6E-81 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily Tharo_1654 658128221b50c5af7d0764f447f6c059 302 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 88 104 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site Tharo_1244 4e1b7333d345d2c3e87be66ea8390ab1 723 SUPERFAMILY SSF52518 412 607 5.54E-20 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_1244 4e1b7333d345d2c3e87be66ea8390ab1 723 SUPERFAMILY SSF54862 602 679 1.09E-6 T 14-10-2018 Tharo_1244 4e1b7333d345d2c3e87be66ea8390ab1 723 Gene3D G3DSA:3.40.50.970 4 201 3.9E-20 T 14-10-2018 Tharo_1244 4e1b7333d345d2c3e87be66ea8390ab1 723 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 444 588 9.4E-15 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Tharo_1244 4e1b7333d345d2c3e87be66ea8390ab1 723 Gene3D G3DSA:3.40.50.970 423 599 1.3E-8 T 14-10-2018 Tharo_1244 4e1b7333d345d2c3e87be66ea8390ab1 723 SUPERFAMILY SSF52518 20 200 7.25E-22 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_0425 5b3fe0d052768788319073588171d026 162 Gene3D G3DSA:2.40.50.90 5 140 9.8E-29 T 14-10-2018 IPR035437 SNase-like, OB-fold superfamily Tharo_0425 5b3fe0d052768788319073588171d026 162 SUPERFAMILY SSF50199 7 134 7.98E-34 T 14-10-2018 Tharo_0425 5b3fe0d052768788319073588171d026 162 SMART SM00318 6 127 1.1E-25 T 14-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 Tharo_0425 5b3fe0d052768788319073588171d026 162 ProSitePatterns PS01123 Thermonuclease family signature 1. 17 42 - T 14-10-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 Tharo_0425 5b3fe0d052768788319073588171d026 162 Pfam PF00565 Staphylococcal nuclease homologue 32 126 4.4E-20 T 14-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 Tharo_2198 56e50c3484503cf7662a8fd566a04aab 279 Gene3D G3DSA:3.30.2350.10 1 256 2.4E-57 T 14-10-2018 Tharo_2198 56e50c3484503cf7662a8fd566a04aab 279 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 50 64 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_2198 56e50c3484503cf7662a8fd566a04aab 279 SUPERFAMILY SSF55120 2 271 1.3E-57 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_2198 56e50c3484503cf7662a8fd566a04aab 279 Pfam PF00849 RNA pseudouridylate synthase 11 203 3.9E-31 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_2499 fa7c56ce789c85e121e69d6fcbb90140 897 Gene3D G3DSA:1.10.390.10 282 461 6.4E-64 T 14-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily Tharo_2499 fa7c56ce789c85e121e69d6fcbb90140 897 Gene3D G3DSA:2.60.40.1730 16 196 3.7E-64 T 14-10-2018 Tharo_2499 fa7c56ce789c85e121e69d6fcbb90140 897 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 178 193 1.4E-9 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Tharo_2499 fa7c56ce789c85e121e69d6fcbb90140 897 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 296 311 1.4E-9 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Tharo_2499 fa7c56ce789c85e121e69d6fcbb90140 897 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 315 327 1.4E-9 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Tharo_2499 fa7c56ce789c85e121e69d6fcbb90140 897 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 128 143 1.4E-9 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Tharo_2499 fa7c56ce789c85e121e69d6fcbb90140 897 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 260 270 1.4E-9 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Tharo_2499 fa7c56ce789c85e121e69d6fcbb90140 897 Gene3D G3DSA:1.25.50.10 569 894 7.7E-104 T 14-10-2018 IPR037144 Peptidase M1, alanyl aminopeptidase, C-terminal domain superfamily Tharo_2499 fa7c56ce789c85e121e69d6fcbb90140 897 SUPERFAMILY SSF63737 6 193 3.66E-39 T 14-10-2018 Tharo_2499 fa7c56ce789c85e121e69d6fcbb90140 897 Pfam PF01433 Peptidase family M1 domain 210 457 2.0E-57 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Tharo_2499 fa7c56ce789c85e121e69d6fcbb90140 897 Gene3D G3DSA:1.10.1740.60 198 281 2.1E-37 T 14-10-2018 Tharo_2499 fa7c56ce789c85e121e69d6fcbb90140 897 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 13 893 0.0 T 14-10-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 Tharo_2499 fa7c56ce789c85e121e69d6fcbb90140 897 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 570 894 4.3E-110 T 14-10-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal Tharo_2499 fa7c56ce789c85e121e69d6fcbb90140 897 Gene3D G3DSA:2.60.40.1840 462 567 4.5E-33 T 14-10-2018 IPR038438 Alanyl aminopeptidase, Ig-like domain superfamily Tharo_2499 fa7c56ce789c85e121e69d6fcbb90140 897 SUPERFAMILY SSF55486 205 467 1.9E-70 T 14-10-2018 Tharo_2499 fa7c56ce789c85e121e69d6fcbb90140 897 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 462 566 3.6E-29 T 14-10-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold Tharo_0954 91c05b95194d3d755f400c37e2f96116 79 Gene3D G3DSA:3.30.70.1290 2 77 4.3E-12 T 14-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 Tharo_0954 91c05b95194d3d755f400c37e2f96116 79 SUPERFAMILY SSF143422 2 68 1.44E-15 T 14-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 Tharo_0954 91c05b95194d3d755f400c37e2f96116 79 Pfam PF01797 Transposase IS200 like 3 68 5.2E-10 T 14-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 Tharo_0954 91c05b95194d3d755f400c37e2f96116 79 SMART SM01321 1 78 2.3E-4 T 14-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 Tharo_0563 7bd5f8ee33ce34d557a1f5d5d6b80811 430 SMART SM00382 215 421 1.4E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0563 7bd5f8ee33ce34d557a1f5d5d6b80811 430 Gene3D G3DSA:1.20.120.140 120 414 1.8E-108 T 14-10-2018 Tharo_0563 7bd5f8ee33ce34d557a1f5d5d6b80811 430 Pfam PF00448 SRP54-type protein, GTPase domain 217 415 2.2E-71 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Tharo_0563 7bd5f8ee33ce34d557a1f5d5d6b80811 430 SUPERFAMILY SSF47364 117 196 1.94E-21 T 14-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 Tharo_0563 7bd5f8ee33ce34d557a1f5d5d6b80811 430 SUPERFAMILY SSF52540 168 416 1.96E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0563 7bd5f8ee33ce34d557a1f5d5d6b80811 430 Pfam PF02881 SRP54-type protein, helical bundle domain 133 197 2.2E-13 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Tharo_0563 7bd5f8ee33ce34d557a1f5d5d6b80811 430 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 145 416 59.255 T 14-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 Tharo_0563 7bd5f8ee33ce34d557a1f5d5d6b80811 430 SMART SM00963 122 202 7.7E-24 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Tharo_0563 7bd5f8ee33ce34d557a1f5d5d6b80811 430 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 389 402 - T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Tharo_0563 7bd5f8ee33ce34d557a1f5d5d6b80811 430 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 145 415 5.6E-102 T 14-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 Tharo_0563 7bd5f8ee33ce34d557a1f5d5d6b80811 430 SMART SM00962 216 416 2.3E-113 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Tharo_0563 7bd5f8ee33ce34d557a1f5d5d6b80811 430 Gene3D G3DSA:3.40.50.300 216 404 1.8E-108 T 14-10-2018 Tharo_0668 8155152037e5e6720c66da208501eaf6 583 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 93 262 3.0E-55 T 14-10-2018 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 Tharo_0668 8155152037e5e6720c66da208501eaf6 583 SUPERFAMILY SSF53474 207 505 9.07E-40 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_0668 8155152037e5e6720c66da208501eaf6 583 Pfam PF12551 Poly-beta-hydroxybutyrate polymerase N terminal 16 54 2.6E-12 T 14-10-2018 IPR022211 Poly-beta-hydroxybutyrate polymerase N-terminal Tharo_0621 a19ea65cec466c26a05ad5c889aa7cec 561 Pfam PF00437 Type II/IV secretion system protein 185 446 2.8E-71 T 14-10-2018 IPR001482 Type II/IV secretion system protein Tharo_0621 a19ea65cec466c26a05ad5c889aa7cec 561 SMART SM00382 307 459 9.9E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0621 a19ea65cec466c26a05ad5c889aa7cec 561 Gene3D G3DSA:3.40.50.300 281 556 2.9E-99 T 14-10-2018 Tharo_0621 a19ea65cec466c26a05ad5c889aa7cec 561 Gene3D G3DSA:3.30.450.90 147 279 4.5E-41 T 14-10-2018 Tharo_0621 a19ea65cec466c26a05ad5c889aa7cec 561 SUPERFAMILY SSF52540 170 552 1.04E-88 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0621 a19ea65cec466c26a05ad5c889aa7cec 561 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 374 388 - T 14-10-2018 IPR001482 Type II/IV secretion system protein Tharo_0621 a19ea65cec466c26a05ad5c889aa7cec 561 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 40 149 3.5E-19 T 14-10-2018 IPR007831 General secretory system II, protein E, N-terminal Tharo_0621 a19ea65cec466c26a05ad5c889aa7cec 561 Gene3D G3DSA:3.30.300.160 61 146 1.0E-7 T 14-10-2018 Tharo_0621 a19ea65cec466c26a05ad5c889aa7cec 561 SUPERFAMILY SSF160246 5 146 1.18E-29 T 14-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily Tharo_0611 089055deddffd59b966509ae11608319 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 256 3.4E-83 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Tharo_0611 089055deddffd59b966509ae11608319 258 SUPERFAMILY SSF52096 1 257 7.91E-91 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_0611 089055deddffd59b966509ae11608319 258 Gene3D G3DSA:1.10.12.10 201 257 6.2E-25 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal Tharo_0611 089055deddffd59b966509ae11608319 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 Tharo_0611 089055deddffd59b966509ae11608319 258 Gene3D G3DSA:3.90.226.10 2 200 9.5E-77 T 14-10-2018 Tharo_2489 ef161f32b9a37c7adf907ae7bed1c964 356 Gene3D G3DSA:3.90.650.10 180 356 9.2E-67 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Tharo_2489 ef161f32b9a37c7adf907ae7bed1c964 356 Pfam PF02769 AIR synthase related protein, C-terminal domain 186 351 9.7E-37 T 14-10-2018 IPR010918 PurM-like, C-terminal domain Tharo_2489 ef161f32b9a37c7adf907ae7bed1c964 356 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 16 354 46.516 T 14-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Tharo_2489 ef161f32b9a37c7adf907ae7bed1c964 356 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 16 344 7.2E-137 T 14-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Tharo_2489 ef161f32b9a37c7adf907ae7bed1c964 356 Pfam PF00586 AIR synthase related protein, N-terminal domain 73 172 5.9E-16 T 14-10-2018 IPR016188 PurM-like, N-terminal domain Tharo_2489 ef161f32b9a37c7adf907ae7bed1c964 356 SUPERFAMILY SSF56042 180 352 1.94E-58 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Tharo_2489 ef161f32b9a37c7adf907ae7bed1c964 356 SUPERFAMILY SSF55326 16 179 3.89E-54 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Tharo_2489 ef161f32b9a37c7adf907ae7bed1c964 356 Gene3D G3DSA:3.30.1330.10 15 179 1.6E-69 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Tharo_2402 23dec87b73d4f49afaad29edaa719b53 209 SUPERFAMILY SSF46626 24 107 2.56E-17 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_2402 23dec87b73d4f49afaad29edaa719b53 209 SUPERFAMILY SSF46626 118 207 1.75E-20 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_2402 23dec87b73d4f49afaad29edaa719b53 209 Gene3D G3DSA:1.10.760.10 114 209 1.3E-26 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_2402 23dec87b73d4f49afaad29edaa719b53 209 Gene3D G3DSA:1.10.760.10 29 108 1.7E-21 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_2402 23dec87b73d4f49afaad29edaa719b53 209 Pfam PF00034 Cytochrome c 124 204 4.8E-9 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_2402 23dec87b73d4f49afaad29edaa719b53 209 Pfam PF00034 Cytochrome c 28 107 4.8E-7 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_2402 23dec87b73d4f49afaad29edaa719b53 209 PIRSF PIRSF000005 1 209 2.0E-62 T 14-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 Tharo_1484 bf2476d8ee91c3b630f292359c9eb109 431 PRINTS PR00143 Citrate synthase signature 381 395 1.7E-54 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 Tharo_1484 bf2476d8ee91c3b630f292359c9eb109 431 PRINTS PR00143 Citrate synthase signature 297 317 1.7E-54 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 Tharo_1484 bf2476d8ee91c3b630f292359c9eb109 431 PRINTS PR00143 Citrate synthase signature 361 377 1.7E-54 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 Tharo_1484 bf2476d8ee91c3b630f292359c9eb109 431 PRINTS PR00143 Citrate synthase signature 166 179 1.7E-54 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 Tharo_1484 bf2476d8ee91c3b630f292359c9eb109 431 PRINTS PR00143 Citrate synthase signature 220 235 1.7E-54 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 Tharo_1484 bf2476d8ee91c3b630f292359c9eb109 431 PRINTS PR00143 Citrate synthase signature 242 270 1.7E-54 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 Tharo_1484 bf2476d8ee91c3b630f292359c9eb109 431 Pfam PF00285 Citrate synthase, C-terminal domain 49 413 7.5E-131 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 Tharo_1484 bf2476d8ee91c3b630f292359c9eb109 431 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 14 424 7.3E-233 T 14-10-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 Tharo_1484 bf2476d8ee91c3b630f292359c9eb109 431 Gene3D G3DSA:2.20.28.60 2 51 1.4E-21 T 14-10-2018 Tharo_1484 bf2476d8ee91c3b630f292359c9eb109 431 Gene3D G3DSA:1.10.580.10 58 413 3.9E-143 T 14-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 Tharo_1484 bf2476d8ee91c3b630f292359c9eb109 431 Gene3D G3DSA:1.10.230.10 269 378 3.9E-143 T 14-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain Tharo_1484 bf2476d8ee91c3b630f292359c9eb109 431 SUPERFAMILY SSF48256 5 430 8.64E-166 T 14-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 Tharo_1484 bf2476d8ee91c3b630f292359c9eb109 431 ProSitePatterns PS00480 Citrate synthase signature. 304 316 - T 14-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 Tharo_1484 bf2476d8ee91c3b630f292359c9eb109 431 PIRSF PIRSF001369 38 431 3.4E-161 T 14-10-2018 IPR024176 Citrate synthase, bacterial-type Tharo_1057 1dacbe08ce0d987f59a07835d6e211cb 289 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 190 196 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Tharo_1057 1dacbe08ce0d987f59a07835d6e211cb 289 SUPERFAMILY SSF53335 27 283 1.22E-54 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_1057 1dacbe08ce0d987f59a07835d6e211cb 289 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 25 285 1.0E-67 T 14-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 Tharo_1057 1dacbe08ce0d987f59a07835d6e211cb 289 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 18 285 40.864 T 14-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 Tharo_1057 1dacbe08ce0d987f59a07835d6e211cb 289 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 33 281 7.1E-85 T 14-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 Tharo_1057 1dacbe08ce0d987f59a07835d6e211cb 289 Gene3D G3DSA:3.40.50.150 95 285 5.5E-55 T 14-10-2018 Tharo_1057 1dacbe08ce0d987f59a07835d6e211cb 289 Gene3D G3DSA:1.10.8.10 16 94 1.7E-20 T 14-10-2018 Tharo_1057 1dacbe08ce0d987f59a07835d6e211cb 289 Pfam PF13847 Methyltransferase domain 120 250 1.2E-14 T 14-10-2018 IPR025714 Methyltransferase domain Tharo_2973 57b683887e99fcab9a259d01b6e0e5bb 509 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 321 410 6.4E-26 T 14-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 Tharo_2973 57b683887e99fcab9a259d01b6e0e5bb 509 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 419 504 2.5E-23 T 14-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 Tharo_2973 57b683887e99fcab9a259d01b6e0e5bb 509 Gene3D G3DSA:3.40.50.1100 16 319 1.4E-141 T 14-10-2018 Tharo_2973 57b683887e99fcab9a259d01b6e0e5bb 509 Gene3D G3DSA:3.40.1020.10 330 506 3.9E-74 T 14-10-2018 IPR038110 Threonine dehydratase, ACT-like domain superfamily KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 Tharo_2973 57b683887e99fcab9a259d01b6e0e5bb 509 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 21 308 7.0E-81 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Tharo_2973 57b683887e99fcab9a259d01b6e0e5bb 509 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 6 504 1.1E-253 T 14-10-2018 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 Tharo_2973 57b683887e99fcab9a259d01b6e0e5bb 509 Gene3D G3DSA:3.40.50.1100 52 148 1.4E-141 T 14-10-2018 Tharo_2973 57b683887e99fcab9a259d01b6e0e5bb 509 SUPERFAMILY SSF53686 4 357 1.44E-104 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Tharo_2973 57b683887e99fcab9a259d01b6e0e5bb 509 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 44 57 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 Tharo_2973 57b683887e99fcab9a259d01b6e0e5bb 509 SUPERFAMILY SSF55021 411 504 7.78E-28 T 14-10-2018 Tharo_2546 6c1e47e837b0ced6780a14651ad60310 138 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 11 136 1.7E-41 T 14-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Tharo_2546 6c1e47e837b0ced6780a14651ad60310 138 SUPERFAMILY SSF52242 9 135 3.66E-43 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 Tharo_2546 6c1e47e837b0ced6780a14651ad60310 138 Pfam PF02310 B12 binding domain 13 123 1.4E-18 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 Tharo_2546 6c1e47e837b0ced6780a14651ad60310 138 Gene3D G3DSA:3.40.50.280 2 138 3.0E-51 T 14-10-2018 Tharo_1690 fa5595b949845f914942732475cc281c 307 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 151 299 4.0E-51 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 Tharo_1690 fa5595b949845f914942732475cc281c 307 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 5 144 4.9E-46 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 Tharo_1690 fa5595b949845f914942732475cc281c 307 Gene3D G3DSA:3.40.50.1370 135 288 4.1E-112 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Tharo_1690 fa5595b949845f914942732475cc281c 307 SUPERFAMILY SSF53671 4 301 2.37E-103 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Tharo_1690 fa5595b949845f914942732475cc281c 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 132 143 6.0E-28 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Tharo_1690 fa5595b949845f914942732475cc281c 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 50 69 6.0E-28 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Tharo_1690 fa5595b949845f914942732475cc281c 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 254 263 6.0E-28 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Tharo_1690 fa5595b949845f914942732475cc281c 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 266 289 6.0E-28 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Tharo_1690 fa5595b949845f914942732475cc281c 307 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 5 301 2.0E-106 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Tharo_1690 fa5595b949845f914942732475cc281c 307 Gene3D G3DSA:3.40.50.1370 6 298 4.1E-112 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Tharo_1690 fa5595b949845f914942732475cc281c 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 48 62 7.7E-28 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Tharo_1690 fa5595b949845f914942732475cc281c 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 81 94 7.7E-28 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Tharo_1690 fa5595b949845f914942732475cc281c 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 280 291 7.7E-28 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Tharo_1690 fa5595b949845f914942732475cc281c 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 218 228 7.7E-28 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Tharo_1690 fa5595b949845f914942732475cc281c 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 121 135 7.7E-28 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Tharo_1690 fa5595b949845f914942732475cc281c 307 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 4 302 77.174 T 14-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 Tharo_1690 fa5595b949845f914942732475cc281c 307 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 50 57 - T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Tharo_1272 fb8a7d8726bf8a75f3a41e06e5ac4055 177 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 140 151 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_1272 fb8a7d8726bf8a75f3a41e06e5ac4055 177 Pfam PF14697 4Fe-4S dicluster domain 103 154 3.4E-13 T 14-10-2018 Tharo_1272 fb8a7d8726bf8a75f3a41e06e5ac4055 177 PIRSF PIRSF005784 1 177 4.1E-57 T 14-10-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 Tharo_1272 fb8a7d8726bf8a75f3a41e06e5ac4055 177 Gene3D G3DSA:3.20.20.20 34 100 1.1E-11 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_1272 fb8a7d8726bf8a75f3a41e06e5ac4055 177 Gene3D G3DSA:3.30.70.20 102 172 7.5E-15 T 14-10-2018 Tharo_1272 fb8a7d8726bf8a75f3a41e06e5ac4055 177 Hamap MF_00463 Ion-translocating oxidoreductase complex subunit B [rsxB]. 1 162 23.983 T 14-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 Tharo_1272 fb8a7d8726bf8a75f3a41e06e5ac4055 177 Pfam PF04060 Putative Fe-S cluster 41 73 1.3E-11 T 14-10-2018 IPR007202 4Fe-4S domain GO:0051536 Tharo_1272 fb8a7d8726bf8a75f3a41e06e5ac4055 177 SUPERFAMILY SSF54862 35 169 3.48E-26 T 14-10-2018 Tharo_1272 fb8a7d8726bf8a75f3a41e06e5ac4055 177 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 2 173 6.5E-57 T 14-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 Tharo_1701 84566d916f7a5a5ce01767d679f1f1f6 203 Gene3D G3DSA:3.90.79.10 6 190 4.3E-53 T 14-10-2018 Tharo_1701 84566d916f7a5a5ce01767d679f1f1f6 203 SUPERFAMILY SSF55811 22 184 8.94E-39 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Tharo_1701 84566d916f7a5a5ce01767d679f1f1f6 203 Pfam PF00293 NUDIX domain 34 116 3.0E-14 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Tharo_1875 0cc4f9853bee84bd7b9b3d65c6c9e12b 272 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 112 132 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 Tharo_1875 0cc4f9853bee84bd7b9b3d65c6c9e12b 272 Gene3D G3DSA:1.10.12.10 214 272 4.0E-21 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal Tharo_1875 0cc4f9853bee84bd7b9b3d65c6c9e12b 272 Gene3D G3DSA:3.90.226.10 3 213 2.7E-63 T 14-10-2018 Tharo_1875 0cc4f9853bee84bd7b9b3d65c6c9e12b 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 19 271 1.8E-46 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Tharo_1875 0cc4f9853bee84bd7b9b3d65c6c9e12b 272 SUPERFAMILY SSF52096 9 271 1.15E-76 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_0362 c594db3dd6549652b8707bccd7c0723f 137 Pfam PF01381 Helix-turn-helix 84 134 9.7E-6 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_0362 c594db3dd6549652b8707bccd7c0723f 137 SMART SM00530 83 136 7.2E-4 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_0362 c594db3dd6549652b8707bccd7c0723f 137 Gene3D G3DSA:1.10.260.40 81 136 7.2E-7 T 14-10-2018 Tharo_0362 c594db3dd6549652b8707bccd7c0723f 137 SUPERFAMILY SSF47413 82 136 5.33E-6 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_2189 f825259129ebd46120d982452d8bf1f9 418 Gene3D G3DSA:3.40.50.450 7 392 1.3E-128 T 14-10-2018 Tharo_2189 f825259129ebd46120d982452d8bf1f9 418 Gene3D G3DSA:3.40.50.460 141 386 1.3E-128 T 14-10-2018 Tharo_2189 f825259129ebd46120d982452d8bf1f9 418 SUPERFAMILY SSF53784 5 399 6.41E-90 T 14-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Tharo_2189 f825259129ebd46120d982452d8bf1f9 418 PIRSF PIRSF036483 2 417 7.9E-147 T 14-10-2018 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 KEGG: 00010+2.7.1.90|KEGG: 00030+2.7.1.90|KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 Tharo_2189 f825259129ebd46120d982452d8bf1f9 418 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 178 194 6.2E-16 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Tharo_2189 f825259129ebd46120d982452d8bf1f9 418 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 8 27 6.2E-16 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Tharo_2189 f825259129ebd46120d982452d8bf1f9 418 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 103 119 6.2E-16 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Tharo_2189 f825259129ebd46120d982452d8bf1f9 418 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 196 213 6.2E-16 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Tharo_2189 f825259129ebd46120d982452d8bf1f9 418 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 136 153 6.2E-16 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Tharo_2189 f825259129ebd46120d982452d8bf1f9 418 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 257 279 6.2E-16 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Tharo_2189 f825259129ebd46120d982452d8bf1f9 418 Pfam PF00365 Phosphofructokinase 10 321 3.6E-48 T 14-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Tharo_2189 f825259129ebd46120d982452d8bf1f9 418 Hamap MF_01978 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 3 398 40.278 T 14-10-2018 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 KEGG: 00010+2.7.1.90|KEGG: 00030+2.7.1.90|KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 Tharo_3239 aa665e80736b44ca5b61091aa2a0595b 92 Gene3D G3DSA:1.10.740.10 3 88 1.1E-9 T 14-10-2018 IPR014737 Transposase, Tn5-like, C-terminal Tharo_3239 aa665e80736b44ca5b61091aa2a0595b 92 SUPERFAMILY SSF53098 2 79 1.52E-15 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_3239 aa665e80736b44ca5b61091aa2a0595b 92 Pfam PF02281 Transposase Tn5 dimerisation domain 2 80 8.1E-27 T 14-10-2018 IPR003201 Transposase Tn5, dimerisation Tharo_1205 ad7ab6d349aa59f2195f1a1de40dd71a 884 SUPERFAMILY SSF56719 30 521 2.49E-176 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Tharo_1205 ad7ab6d349aa59f2195f1a1de40dd71a 884 SUPERFAMILY SSF101904 533 849 3.01E-113 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal Tharo_1205 ad7ab6d349aa59f2195f1a1de40dd71a 884 Gene3D G3DSA:3.30.1360.40 236 333 6.4E-223 T 14-10-2018 Tharo_1205 ad7ab6d349aa59f2195f1a1de40dd71a 884 Gene3D G3DSA:1.10.268.10 370 493 6.4E-223 T 14-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Tharo_1205 ad7ab6d349aa59f2195f1a1de40dd71a 884 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 501 3.9E-151 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Tharo_1205 ad7ab6d349aa59f2195f1a1de40dd71a 884 Gene3D G3DSA:2.120.10.90 531 842 3.2E-128 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal Tharo_1205 ad7ab6d349aa59f2195f1a1de40dd71a 884 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 10 841 0.0 T 14-10-2018 Tharo_1205 ad7ab6d349aa59f2195f1a1de40dd71a 884 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 7 842 24.279 T 14-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Tharo_1205 ad7ab6d349aa59f2195f1a1de40dd71a 884 Gene3D G3DSA:3.90.199.10 33 520 6.4E-223 T 14-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 Tharo_1205 ad7ab6d349aa59f2195f1a1de40dd71a 884 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 794 838 2.8E-9 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Tharo_1205 ad7ab6d349aa59f2195f1a1de40dd71a 884 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 538 585 4.0E-11 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Tharo_1205 ad7ab6d349aa59f2195f1a1de40dd71a 884 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 588 637 3.2E-10 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Tharo_1205 ad7ab6d349aa59f2195f1a1de40dd71a 884 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 744 790 8.7E-14 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Tharo_1205 ad7ab6d349aa59f2195f1a1de40dd71a 884 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 693 738 4.1E-14 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Tharo_1205 ad7ab6d349aa59f2195f1a1de40dd71a 884 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 646 688 2.5E-8 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Tharo_1205 ad7ab6d349aa59f2195f1a1de40dd71a 884 SMART SM00434 11 499 3.5E-288 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Tharo_3318 a55e52ce71dd9a55f1ac7048114481c3 322 SMART SM00220 27 300 1.0E-27 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Tharo_3318 a55e52ce71dd9a55f1ac7048114481c3 322 Pfam PF00069 Protein kinase domain 27 292 3.3E-32 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Tharo_3318 a55e52ce71dd9a55f1ac7048114481c3 322 Gene3D G3DSA:3.30.200.20 5 125 8.4E-17 T 14-10-2018 Tharo_3318 a55e52ce71dd9a55f1ac7048114481c3 322 Gene3D G3DSA:1.10.510.10 126 300 6.8E-32 T 14-10-2018 Tharo_3318 a55e52ce71dd9a55f1ac7048114481c3 322 SUPERFAMILY SSF56112 23 297 2.29E-55 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Tharo_1491 7e5a5028a1da7c9da876f3add333547d 401 Gene3D G3DSA:3.90.105.10 29 173 4.6E-126 T 14-10-2018 Tharo_1491 7e5a5028a1da7c9da876f3add333547d 401 Gene3D G3DSA:2.40.340.10 326 391 4.6E-126 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Tharo_1491 7e5a5028a1da7c9da876f3add333547d 401 Gene3D G3DSA:3.40.980.10 174 325 4.6E-126 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily Tharo_1491 7e5a5028a1da7c9da876f3add333547d 401 Pfam PF03454 MoeA C-terminal region (domain IV) 330 395 8.9E-13 T 14-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Tharo_1491 7e5a5028a1da7c9da876f3add333547d 401 Gene3D G3DSA:2.170.190.11 49 140 4.6E-126 T 14-10-2018 Tharo_1491 7e5a5028a1da7c9da876f3add333547d 401 SUPERFAMILY SSF63867 327 398 3.53E-15 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Tharo_1491 7e5a5028a1da7c9da876f3add333547d 401 Pfam PF03453 MoeA N-terminal region (domain I and II) 7 166 2.3E-40 T 14-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Tharo_1491 7e5a5028a1da7c9da876f3add333547d 401 SMART SM00852 179 316 3.8E-45 T 14-10-2018 IPR001453 MoaB/Mog domain Tharo_1491 7e5a5028a1da7c9da876f3add333547d 401 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 176 312 4.2E-28 T 14-10-2018 IPR001453 MoaB/Mog domain Tharo_1491 7e5a5028a1da7c9da876f3add333547d 401 SUPERFAMILY SSF63882 5 174 1.7E-49 T 14-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Tharo_1491 7e5a5028a1da7c9da876f3add333547d 401 Pfam PF00994 Probable molybdopterin binding domain 179 314 7.5E-25 T 14-10-2018 IPR001453 MoaB/Mog domain Tharo_1491 7e5a5028a1da7c9da876f3add333547d 401 SUPERFAMILY SSF53218 177 320 3.93E-44 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily Tharo_2730 a7f642305bc0c676f39eb7e6b0b3e878 1404 Pfam PF05000 RNA polymerase Rpb1, domain 4 675 765 4.4E-19 T 14-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2730 a7f642305bc0c676f39eb7e6b0b3e878 1404 Pfam PF04983 RNA polymerase Rpb1, domain 3 491 646 2.3E-25 T 14-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2730 a7f642305bc0c676f39eb7e6b0b3e878 1404 Gene3D G3DSA:1.10.274.100 492 642 1.3E-35 T 14-10-2018 Tharo_2730 a7f642305bc0c676f39eb7e6b0b3e878 1404 Gene3D G3DSA:2.40.50.100 1156 1219 1.2E-64 T 14-10-2018 Tharo_2730 a7f642305bc0c676f39eb7e6b0b3e878 1404 Gene3D G3DSA:1.10.40.90 376 418 2.0E-20 T 14-10-2018 Tharo_2730 a7f642305bc0c676f39eb7e6b0b3e878 1404 Gene3D G3DSA:1.10.1790.20 1140 1318 1.2E-64 T 14-10-2018 Tharo_2730 a7f642305bc0c676f39eb7e6b0b3e878 1404 SUPERFAMILY SSF64484 18 1368 0.0 T 14-10-2018 Tharo_2730 a7f642305bc0c676f39eb7e6b0b3e878 1404 Pfam PF00623 RNA polymerase Rpb1, domain 2 396 487 1.5E-26 T 14-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2730 a7f642305bc0c676f39eb7e6b0b3e878 1404 Pfam PF00623 RNA polymerase Rpb1, domain 2 346 400 2.9E-8 T 14-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2730 a7f642305bc0c676f39eb7e6b0b3e878 1404 Pfam PF04998 RNA polymerase Rpb1, domain 5 768 1320 4.8E-75 T 14-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2730 a7f642305bc0c676f39eb7e6b0b3e878 1404 Gene3D G3DSA:2.40.50.100 950 1025 9.7E-27 T 14-10-2018 Tharo_2730 a7f642305bc0c676f39eb7e6b0b3e878 1404 Gene3D G3DSA:2.40.50.100 1026 1131 6.1E-30 T 14-10-2018 Tharo_2730 a7f642305bc0c676f39eb7e6b0b3e878 1404 Gene3D G3DSA:1.10.132.30 643 792 8.0E-65 T 14-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2730 a7f642305bc0c676f39eb7e6b0b3e878 1404 SMART SM00663 237 516 5.0E-178 T 14-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2730 a7f642305bc0c676f39eb7e6b0b3e878 1404 Gene3D G3DSA:1.10.150.390 1320 1380 1.3E-28 T 14-10-2018 Tharo_2730 a7f642305bc0c676f39eb7e6b0b3e878 1404 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 22 1371 0.0 T 14-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2730 a7f642305bc0c676f39eb7e6b0b3e878 1404 Pfam PF04997 RNA polymerase Rpb1, domain 1 17 344 3.4E-85 T 14-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_2730 a7f642305bc0c676f39eb7e6b0b3e878 1404 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 13 1378 18.78 T 14-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Tharo_0394 2f6f4d58fc69ebf81373f012c578ed98 193 Pfam PF05280 Flagellar transcriptional activator (FlhC) 1 170 3.1E-79 T 14-10-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 Tharo_0394 2f6f4d58fc69ebf81373f012c578ed98 193 PIRSF PIRSF003159 1 181 2.9E-84 T 14-10-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 Tharo_0394 2f6f4d58fc69ebf81373f012c578ed98 193 Hamap MF_01891 Flagellar transcriptional regulator FlhC [flhC]. 1 183 43.894 T 14-10-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 Tharo_0394 2f6f4d58fc69ebf81373f012c578ed98 193 SUPERFAMILY SSF160930 6 160 1.44E-60 T 14-10-2018 Tharo_0394 2f6f4d58fc69ebf81373f012c578ed98 193 ProDom PD016592 ACTIVATOR TRANSCRIPTIONAL FLAGELLUM FLAGELLAR TRANSCRIPTION FLHC RNA DNA-BINDING REGULATION DNA-DIRECTED 1 168 4.0E-72 T 14-10-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 Tharo_3088 dcc2d7b51332582d13b13e72ed733e2a 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.7E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3088 dcc2d7b51332582d13b13e72ed733e2a 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.7E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3088 dcc2d7b51332582d13b13e72ed733e2a 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.7E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3088 dcc2d7b51332582d13b13e72ed733e2a 250 Gene3D G3DSA:3.40.50.720 1 248 5.0E-52 T 14-10-2018 Tharo_3088 dcc2d7b51332582d13b13e72ed733e2a 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 241 4.1E-38 T 14-10-2018 Tharo_3088 dcc2d7b51332582d13b13e72ed733e2a 250 SUPERFAMILY SSF51735 6 244 9.3E-56 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_3088 dcc2d7b51332582d13b13e72ed733e2a 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.1E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3088 dcc2d7b51332582d13b13e72ed733e2a 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.1E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3088 dcc2d7b51332582d13b13e72ed733e2a 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.1E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3088 dcc2d7b51332582d13b13e72ed733e2a 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 2.1E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3088 dcc2d7b51332582d13b13e72ed733e2a 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.1E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3088 dcc2d7b51332582d13b13e72ed733e2a 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.1E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2048 8f1b301c4358af55ceb05d6368737b75 101 SMART SM00966 6 48 1.6E-6 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Tharo_2048 8f1b301c4358af55ceb05d6368737b75 101 Gene3D G3DSA:2.10.260.10 2 78 6.9E-16 T 14-10-2018 Tharo_2048 8f1b301c4358af55ceb05d6368737b75 101 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 6 46 9.5E-11 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Tharo_2048 8f1b301c4358af55ceb05d6368737b75 101 SUPERFAMILY SSF89447 1 71 1.91E-15 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily Tharo_0887 324224fa2d61691180410dc6fd4dbecd 221 PRINTS PR01021 OMPA domain signature 116 138 5.5E-13 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Tharo_0887 324224fa2d61691180410dc6fd4dbecd 221 PRINTS PR01021 OMPA domain signature 146 161 5.5E-13 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Tharo_0887 324224fa2d61691180410dc6fd4dbecd 221 PRINTS PR01021 OMPA domain signature 161 177 5.5E-13 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Tharo_0887 324224fa2d61691180410dc6fd4dbecd 221 Pfam PF00691 OmpA family 116 210 4.0E-21 T 14-10-2018 IPR006665 OmpA-like domain Tharo_0887 324224fa2d61691180410dc6fd4dbecd 221 Pfam PF13488 Glycine zipper 33 83 5.4E-12 T 14-10-2018 IPR039567 Glycine zipper domain Tharo_0887 324224fa2d61691180410dc6fd4dbecd 221 SUPERFAMILY SSF103088 103 216 6.28E-38 T 14-10-2018 IPR036737 OmpA-like domain superfamily Tharo_0887 324224fa2d61691180410dc6fd4dbecd 221 Gene3D G3DSA:3.30.1330.60 78 220 4.9E-44 T 14-10-2018 IPR036737 OmpA-like domain superfamily Tharo_0887 324224fa2d61691180410dc6fd4dbecd 221 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 161 178 3.2E-7 T 14-10-2018 Tharo_0887 324224fa2d61691180410dc6fd4dbecd 221 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 199 219 3.2E-7 T 14-10-2018 Tharo_0887 324224fa2d61691180410dc6fd4dbecd 221 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 179 198 3.2E-7 T 14-10-2018 Tharo_3409 8cb25da41af84df116403e16fedd2e99 299 SUPERFAMILY SSF52540 4 287 5.75E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3409 8cb25da41af84df116403e16fedd2e99 299 TIGRFAM TIGR02782 TrbB_P: P-type conjugative transfer ATPase TrbB 1 295 3.2E-131 T 14-10-2018 IPR014149 Conjugative transfer, TrbB GO:0000746|GO:0005737 Tharo_3409 8cb25da41af84df116403e16fedd2e99 299 Gene3D G3DSA:3.40.50.300 101 298 6.2E-54 T 14-10-2018 Tharo_3409 8cb25da41af84df116403e16fedd2e99 299 Pfam PF00437 Type II/IV secretion system protein 7 273 1.2E-74 T 14-10-2018 IPR001482 Type II/IV secretion system protein Tharo_3409 8cb25da41af84df116403e16fedd2e99 299 Gene3D G3DSA:3.30.450.90 3 100 9.0E-12 T 14-10-2018 Tharo_2498 b92c39a1ce339da154e99752005c8c54 148 SMART SM00116 80 127 1.5E-9 T 14-10-2018 IPR000644 CBS domain Tharo_2498 b92c39a1ce339da154e99752005c8c54 148 SMART SM00116 15 62 6.6E-8 T 14-10-2018 IPR000644 CBS domain Tharo_2498 b92c39a1ce339da154e99752005c8c54 148 Gene3D G3DSA:3.10.580.10 1 143 1.7E-45 T 14-10-2018 Tharo_2498 b92c39a1ce339da154e99752005c8c54 148 Pfam PF00571 CBS domain 17 61 1.1E-7 T 14-10-2018 IPR000644 CBS domain Tharo_2498 b92c39a1ce339da154e99752005c8c54 148 Pfam PF00571 CBS domain 73 126 1.6E-14 T 14-10-2018 IPR000644 CBS domain Tharo_2498 b92c39a1ce339da154e99752005c8c54 148 SUPERFAMILY SSF54631 6 142 2.53E-34 T 14-10-2018 Tharo_3354 2d5658bf1909298d0b5eafad88e3b9d4 217 SUPERFAMILY SSF48613 1 213 2.92E-60 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 Tharo_3354 2d5658bf1909298d0b5eafad88e3b9d4 217 Gene3D G3DSA:1.20.910.10 3 217 2.3E-55 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 Tharo_3354 2d5658bf1909298d0b5eafad88e3b9d4 217 Pfam PF14518 Iron-containing redox enzyme 39 206 1.0E-26 T 14-10-2018 Tharo_3354 2d5658bf1909298d0b5eafad88e3b9d4 217 SMART SM01236 73 170 1.9E-4 T 14-10-2018 Tharo_3058 660ce5e66f0b1afa94cbb4323f2a5e8e 381 Gene3D G3DSA:3.40.50.720 139 317 3.1E-126 T 14-10-2018 Tharo_3058 660ce5e66f0b1afa94cbb4323f2a5e8e 381 SUPERFAMILY SSF51735 139 312 6.91E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_3058 660ce5e66f0b1afa94cbb4323f2a5e8e 381 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 14-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 Tharo_3058 660ce5e66f0b1afa94cbb4323f2a5e8e 381 SMART SM01003 6 139 5.0E-53 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Tharo_3058 660ce5e66f0b1afa94cbb4323f2a5e8e 381 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 144 365 1.6E-66 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Tharo_3058 660ce5e66f0b1afa94cbb4323f2a5e8e 381 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 6 139 2.4E-32 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Tharo_3058 660ce5e66f0b1afa94cbb4323f2a5e8e 381 SMART SM01002 148 310 4.6E-79 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Tharo_3058 660ce5e66f0b1afa94cbb4323f2a5e8e 381 Gene3D G3DSA:3.40.50.720 5 362 3.1E-126 T 14-10-2018 Tharo_3058 660ce5e66f0b1afa94cbb4323f2a5e8e 381 SUPERFAMILY SSF52283 4 170 1.79E-41 T 14-10-2018 Tharo_2165 b80de7a10a46973baffd62adab1e31ca 153 Pfam PF00075 RNase H 3 141 4.4E-48 T 14-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 Tharo_2165 b80de7a10a46973baffd62adab1e31ca 153 Hamap MF_00042 Ribonuclease H [rnhA]. 2 150 34.959 T 14-10-2018 IPR022892 Ribonuclease HI GO:0004523 Tharo_2165 b80de7a10a46973baffd62adab1e31ca 153 SUPERFAMILY SSF53098 5 142 1.64E-55 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_2165 b80de7a10a46973baffd62adab1e31ca 153 Gene3D G3DSA:3.30.420.10 1 150 8.0E-57 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_1582 f7e1e04864477ff6dba046c157ee7773 343 Pfam PF13592 Winged helix-turn helix 96 154 2.6E-18 T 14-10-2018 IPR025959 Winged helix-turn helix domain Tharo_1582 f7e1e04864477ff6dba046c157ee7773 343 Pfam PF13358 DDE superfamily endonuclease 170 303 1.4E-33 T 14-10-2018 IPR038717 Tc1-like transposase, DDE domain Tharo_1582 f7e1e04864477ff6dba046c157ee7773 343 Gene3D G3DSA:3.30.420.470 138 338 1.5E-16 T 14-10-2018 Tharo_1582 f7e1e04864477ff6dba046c157ee7773 343 Pfam PF06056 Putative ATPase subunit of terminase (gpP-like) 14 57 7.5E-7 T 14-10-2018 IPR010332 ATPase terminase subunit, putative GO:0005524|GO:0019069 Tharo_1582 f7e1e04864477ff6dba046c157ee7773 343 SUPERFAMILY SSF46689 12 130 7.17E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_3233 e051fd4214b983a4311cbcf358942857 440 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 43 88 7.1E-14 T 14-10-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger Tharo_3233 e051fd4214b983a4311cbcf358942857 440 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 95 144 5.9E-14 T 14-10-2018 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain Tharo_3233 e051fd4214b983a4311cbcf358942857 440 Pfam PF01610 Transposase 159 409 4.8E-71 T 14-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain Tharo_3327 e051fd4214b983a4311cbcf358942857 440 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 43 88 7.1E-14 T 14-10-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger Tharo_3327 e051fd4214b983a4311cbcf358942857 440 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 95 144 5.9E-14 T 14-10-2018 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain Tharo_3327 e051fd4214b983a4311cbcf358942857 440 Pfam PF01610 Transposase 159 409 4.8E-71 T 14-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain Tharo_0546 5251f8e1eb6f64d7ea708e34554beeb0 437 Gene3D G3DSA:1.10.287.130 206 279 2.0E-5 T 14-10-2018 Tharo_0546 5251f8e1eb6f64d7ea708e34554beeb0 437 Gene3D G3DSA:3.30.565.10 289 432 4.7E-20 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_0546 5251f8e1eb6f64d7ea708e34554beeb0 437 SUPERFAMILY SSF47384 214 275 1.45E-5 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_0546 5251f8e1eb6f64d7ea708e34554beeb0 437 SUPERFAMILY SSF55874 291 432 4.58E-21 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_0546 5251f8e1eb6f64d7ea708e34554beeb0 437 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 331 432 1.1E-11 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_0546 5251f8e1eb6f64d7ea708e34554beeb0 437 SMART SM00387 326 434 2.2E-12 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1970 6e9abaa7a84cc3333e98580c5c682fc2 96 Gene3D G3DSA:3.30.300.90 4 93 1.9E-24 T 14-10-2018 Tharo_1970 6e9abaa7a84cc3333e98580c5c682fc2 96 SUPERFAMILY SSF82657 4 92 3.4E-24 T 14-10-2018 IPR036065 BolA-like superfamily Tharo_1970 6e9abaa7a84cc3333e98580c5c682fc2 96 Pfam PF01722 BolA-like protein 15 89 4.6E-24 T 14-10-2018 IPR002634 BolA protein Tharo_1970 6e9abaa7a84cc3333e98580c5c682fc2 96 PIRSF PIRSF003113 1 96 4.2E-24 T 14-10-2018 IPR002634 BolA protein Tharo_0172 c054c594d0121e99bf0e9eae5b5e6dd9 418 Pfam PF13751 Transposase DDE domain 333 396 1.1E-12 T 14-10-2018 IPR025668 Transposase DDE domain Tharo_0172 c054c594d0121e99bf0e9eae5b5e6dd9 418 Pfam PF05598 Transposase domain (DUF772) 45 111 6.8E-10 T 14-10-2018 IPR008490 Transposase InsH, N-terminal Tharo_1867 c054c594d0121e99bf0e9eae5b5e6dd9 418 Pfam PF13751 Transposase DDE domain 333 396 1.1E-12 T 14-10-2018 IPR025668 Transposase DDE domain Tharo_1867 c054c594d0121e99bf0e9eae5b5e6dd9 418 Pfam PF05598 Transposase domain (DUF772) 45 111 6.8E-10 T 14-10-2018 IPR008490 Transposase InsH, N-terminal Tharo_1773 c054c594d0121e99bf0e9eae5b5e6dd9 418 Pfam PF13751 Transposase DDE domain 333 396 1.1E-12 T 14-10-2018 IPR025668 Transposase DDE domain Tharo_1773 c054c594d0121e99bf0e9eae5b5e6dd9 418 Pfam PF05598 Transposase domain (DUF772) 45 111 6.8E-10 T 14-10-2018 IPR008490 Transposase InsH, N-terminal Tharo_3263 1b8f8ece5ef6e1abcc2cbdb6ad36dbd7 257 Pfam PF04230 Polysaccharide pyruvyl transferase 42 193 1.1E-8 T 14-10-2018 IPR007345 Polysaccharide pyruvyl transferase Tharo_1309 5b91ba2c08b9dac0f61a8195ca8e88a3 81 SUPERFAMILY SSF54862 4 76 1.73E-17 T 14-10-2018 Tharo_1309 5b91ba2c08b9dac0f61a8195ca8e88a3 81 Gene3D G3DSA:3.30.70.20 2 81 2.9E-33 T 14-10-2018 Tharo_1309 5b91ba2c08b9dac0f61a8195ca8e88a3 81 Pfam PF00037 4Fe-4S binding domain 5 25 8.2E-7 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_1309 5b91ba2c08b9dac0f61a8195ca8e88a3 81 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_0860 9b5125d0aa752c430508bb7232c51c0e 266 Pfam PF01464 Transglycosylase SLT domain 140 229 4.5E-18 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 Tharo_0860 9b5125d0aa752c430508bb7232c51c0e 266 SUPERFAMILY SSF53955 138 253 5.63E-25 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily Tharo_0860 9b5125d0aa752c430508bb7232c51c0e 266 Gene3D G3DSA:1.10.530.10 119 249 2.2E-25 T 14-10-2018 Tharo_1526 e861a94547aaf429f71b800bea7e071d 809 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 646 752 8.1E-9 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 Tharo_1526 e861a94547aaf429f71b800bea7e071d 809 Gene3D G3DSA:3.40.50.300 244 449 3.0E-61 T 14-10-2018 Tharo_1526 e861a94547aaf429f71b800bea7e071d 809 Gene3D G3DSA:3.40.50.300 7 160 2.3E-26 T 14-10-2018 Tharo_1526 e861a94547aaf429f71b800bea7e071d 809 Gene3D G3DSA:1.10.8.60 450 536 9.4E-10 T 14-10-2018 Tharo_1526 e861a94547aaf429f71b800bea7e071d 809 Gene3D G3DSA:3.30.230.10 543 776 1.1E-94 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Tharo_1526 e861a94547aaf429f71b800bea7e071d 809 SUPERFAMILY SSF54211 563 757 4.55E-36 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_1526 e861a94547aaf429f71b800bea7e071d 809 Pfam PF13654 AAA domain 26 539 2.0E-175 T 14-10-2018 Tharo_1526 e861a94547aaf429f71b800bea7e071d 809 SUPERFAMILY SSF52540 36 537 2.66E-6 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0063 af9bdc657fe9b0c04fb403764fcb8d9a 315 Gene3D G3DSA:1.10.10.10 1 85 4.6E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0063 af9bdc657fe9b0c04fb403764fcb8d9a 315 Gene3D G3DSA:3.40.190.10 92 290 1.9E-75 T 14-10-2018 Tharo_0063 af9bdc657fe9b0c04fb403764fcb8d9a 315 Pfam PF03466 LysR substrate binding domain 88 295 4.9E-47 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_0063 af9bdc657fe9b0c04fb403764fcb8d9a 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.2E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0063 af9bdc657fe9b0c04fb403764fcb8d9a 315 SUPERFAMILY SSF46785 1 83 1.41E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0063 af9bdc657fe9b0c04fb403764fcb8d9a 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.8E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0063 af9bdc657fe9b0c04fb403764fcb8d9a 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.8E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0063 af9bdc657fe9b0c04fb403764fcb8d9a 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.8E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_0063 af9bdc657fe9b0c04fb403764fcb8d9a 315 SUPERFAMILY SSF53850 88 296 2.04E-39 T 14-10-2018 Tharo_0063 af9bdc657fe9b0c04fb403764fcb8d9a 315 Gene3D G3DSA:3.40.190.10 161 267 1.9E-75 T 14-10-2018 Tharo_1775 fe513d8d43a430a184f9ae68294b42a7 213 Gene3D G3DSA:3.30.420.10 40 191 6.8E-16 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_1775 fe513d8d43a430a184f9ae68294b42a7 213 SUPERFAMILY SSF53098 35 192 1.84E-27 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_1775 fe513d8d43a430a184f9ae68294b42a7 213 SMART SM00479 44 191 0.0014 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Tharo_2205 4bd7862130e526f955e3b8142115208d 223 PIRSF PIRSF006091 2 216 2.7E-63 T 14-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 Tharo_2205 4bd7862130e526f955e3b8142115208d 223 SMART SM00900 107 204 1.1E-19 T 14-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 Tharo_2205 4bd7862130e526f955e3b8142115208d 223 Pfam PF04205 FMN-binding domain 107 198 1.0E-12 T 14-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 Tharo_2205 4bd7862130e526f955e3b8142115208d 223 Hamap MF_00479 Ion-translocating oxidoreductase complex subunit G [rsxG]. 8 206 21.841 T 14-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 Tharo_2205 4bd7862130e526f955e3b8142115208d 223 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 16 204 7.4E-45 T 14-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 Tharo_3009 5417b952f6870171a35a11a98c5c9632 560 Gene3D G3DSA:3.50.50.60 28 364 2.2E-87 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_3009 5417b952f6870171a35a11a98c5c9632 560 Gene3D G3DSA:3.30.70.2450 204 293 2.2E-87 T 14-10-2018 Tharo_3009 5417b952f6870171a35a11a98c5c9632 560 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 337 355 2.6E-32 T 14-10-2018 Tharo_3009 5417b952f6870171a35a11a98c5c9632 560 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 319 2.6E-32 T 14-10-2018 Tharo_3009 5417b952f6870171a35a11a98c5c9632 560 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 175 190 2.6E-32 T 14-10-2018 Tharo_3009 5417b952f6870171a35a11a98c5c9632 560 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 27 49 2.6E-32 T 14-10-2018 Tharo_3009 5417b952f6870171a35a11a98c5c9632 560 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 319 335 2.6E-32 T 14-10-2018 Tharo_3009 5417b952f6870171a35a11a98c5c9632 560 Pfam PF01494 FAD binding domain 27 368 1.8E-62 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 Tharo_3009 5417b952f6870171a35a11a98c5c9632 560 SUPERFAMILY SSF51905 25 403 1.25E-63 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_3009 5417b952f6870171a35a11a98c5c9632 560 Gene3D G3DSA:3.40.30.120 397 559 9.7E-12 T 14-10-2018 Tharo_0092 83047cc32d0e696b03acc8ab58a0821e 568 Gene3D G3DSA:3.20.20.70 11 375 1.6E-151 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_0092 83047cc32d0e696b03acc8ab58a0821e 568 SUPERFAMILY SSF51569 21 329 4.21E-97 T 14-10-2018 Tharo_0092 83047cc32d0e696b03acc8ab58a0821e 568 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 39 55 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Tharo_0092 83047cc32d0e696b03acc8ab58a0821e 568 Gene3D G3DSA:3.30.160.270 376 552 1.1E-50 T 14-10-2018 Tharo_0092 83047cc32d0e696b03acc8ab58a0821e 568 SUPERFAMILY SSF110921 443 551 2.35E-25 T 14-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Tharo_0092 83047cc32d0e696b03acc8ab58a0821e 568 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 242 255 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Tharo_0092 83047cc32d0e696b03acc8ab58a0821e 568 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 6 551 8.8E-229 T 14-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Tharo_0092 83047cc32d0e696b03acc8ab58a0821e 568 Pfam PF00682 HMGL-like 32 312 2.2E-73 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Tharo_0092 83047cc32d0e696b03acc8ab58a0821e 568 Pfam PF08502 LeuA allosteric (dimerisation) domain 421 552 2.2E-18 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Tharo_0092 83047cc32d0e696b03acc8ab58a0821e 568 SUPERFAMILY SSF89000 387 437 5.89E-15 T 14-10-2018 Tharo_0092 83047cc32d0e696b03acc8ab58a0821e 568 SMART SM00917 421 553 3.4E-25 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Tharo_0092 83047cc32d0e696b03acc8ab58a0821e 568 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 7 554 52.283 T 14-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Tharo_0151 35f3719a4f4b26747f5033ac5e8d83d1 72 SMART SM00530 5 61 0.001 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_0151 35f3719a4f4b26747f5033ac5e8d83d1 72 SUPERFAMILY SSF47413 1 68 1.57E-11 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_0151 35f3719a4f4b26747f5033ac5e8d83d1 72 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 5 67 6.7E-20 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_0151 35f3719a4f4b26747f5033ac5e8d83d1 72 Gene3D G3DSA:1.10.260.40 1 68 5.1E-10 T 14-10-2018 Tharo_1748 16a2a6788b3b6f73ef77b10c9003546f 402 Pfam PF02239 Cytochrome D1 heme domain 38 396 2.1E-100 T 14-10-2018 Tharo_1748 16a2a6788b3b6f73ef77b10c9003546f 402 SUPERFAMILY SSF51004 22 398 1.14E-72 T 14-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily Tharo_1748 16a2a6788b3b6f73ef77b10c9003546f 402 Gene3D G3DSA:2.140.10.20 24 399 1.4E-42 T 14-10-2018 IPR003143 Cytochrome cd1-nitrite reductase, C-terminal domain superfamily Tharo_2474 87978195ceb311ac75d255edb121a285 336 Pfam PF14840 Processivity clamp loader gamma complex DNA pol III C-term 219 334 5.1E-10 T 14-10-2018 IPR032780 DNA polymerase III subunit delta, C-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_2474 87978195ceb311ac75d255edb121a285 336 SUPERFAMILY SSF48019 211 333 3.15E-26 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 Tharo_2474 87978195ceb311ac75d255edb121a285 336 Gene3D G3DSA:1.20.272.10 215 336 2.8E-30 T 14-10-2018 Tharo_2474 87978195ceb311ac75d255edb121a285 336 Gene3D G3DSA:1.10.8.60 142 211 5.5E-26 T 14-10-2018 Tharo_2474 87978195ceb311ac75d255edb121a285 336 SUPERFAMILY SSF52540 3 209 4.67E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2474 87978195ceb311ac75d255edb121a285 336 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 17 333 4.5E-83 T 14-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 Tharo_2474 87978195ceb311ac75d255edb121a285 336 Pfam PF06144 DNA polymerase III, delta subunit 22 188 6.5E-21 T 14-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 Tharo_2474 87978195ceb311ac75d255edb121a285 336 Gene3D G3DSA:3.40.50.300 1 138 1.0E-45 T 14-10-2018 Tharo_1124 f084173599d4f9fd7571fcb84cdce46a 590 TIGRFAM TIGR03104 trio_amidotrans: asparagine synthase family amidotransferase 1 588 1.3E-303 T 14-10-2018 IPR017535 Asparagine synthase family amidotransferase Tharo_1124 f084173599d4f9fd7571fcb84cdce46a 590 Pfam PF00733 Asparagine synthase 246 586 1.0E-84 T 14-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 Tharo_1124 f084173599d4f9fd7571fcb84cdce46a 590 Gene3D G3DSA:3.60.20.10 4 185 4.6E-56 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Tharo_1124 f084173599d4f9fd7571fcb84cdce46a 590 SUPERFAMILY SSF52402 236 564 7.75E-79 T 14-10-2018 Tharo_1124 f084173599d4f9fd7571fcb84cdce46a 590 SUPERFAMILY SSF56235 1 224 3.0E-60 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Tharo_1124 f084173599d4f9fd7571fcb84cdce46a 590 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 519 1.6E-129 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 Tharo_1124 f084173599d4f9fd7571fcb84cdce46a 590 Pfam PF13537 Glutamine amidotransferase domain 47 167 1.2E-42 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain Tharo_1124 f084173599d4f9fd7571fcb84cdce46a 590 PIRSF PIRSF001589 1 590 2.7E-219 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 Tharo_1410 916156842273b6782b5f08b5342a36d4 414 TIGRFAM TIGR01224 hutI: imidazolonepropionase 27 404 2.5E-133 T 14-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 Tharo_1410 916156842273b6782b5f08b5342a36d4 414 SUPERFAMILY SSF51556 64 364 2.58E-84 T 14-10-2018 IPR032466 Metal-dependent hydrolase Tharo_1410 916156842273b6782b5f08b5342a36d4 414 SUPERFAMILY SSF51338 344 404 3.41E-15 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Tharo_1410 916156842273b6782b5f08b5342a36d4 414 Gene3D G3DSA:3.20.20.140 65 366 7.5E-152 T 14-10-2018 Tharo_1410 916156842273b6782b5f08b5342a36d4 414 SUPERFAMILY SSF51338 9 87 4.68E-7 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Tharo_1410 916156842273b6782b5f08b5342a36d4 414 Pfam PF07969 Amidohydrolase family 106 386 2.3E-15 T 14-10-2018 IPR013108 Amidohydrolase 3 Tharo_1410 916156842273b6782b5f08b5342a36d4 414 Hamap MF_00372 Imidazolonepropionase [hutI]. 8 406 39.91 T 14-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 Tharo_1410 916156842273b6782b5f08b5342a36d4 414 Gene3D G3DSA:2.30.40.10 27 403 7.5E-152 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Tharo_3386 b0cf3e03b271bec39f1e11a99dd11142 366 Gene3D G3DSA:3.20.20.210 8 366 1.3E-157 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 Tharo_3386 b0cf3e03b271bec39f1e11a99dd11142 366 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 16 359 50.127 T 14-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 Tharo_3386 b0cf3e03b271bec39f1e11a99dd11142 366 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 15 358 4.7E-135 T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 Tharo_3386 b0cf3e03b271bec39f1e11a99dd11142 366 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 152 168 - T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 Tharo_3386 b0cf3e03b271bec39f1e11a99dd11142 366 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 19 357 1.0E-128 T 14-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 Tharo_3386 b0cf3e03b271bec39f1e11a99dd11142 366 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 32 41 - T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 Tharo_3386 b0cf3e03b271bec39f1e11a99dd11142 366 SUPERFAMILY SSF51726 13 361 1.05E-119 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 Tharo_0484 f5ab85cb2d48addb729210271f062ae5 391 Gene3D G3DSA:3.40.640.10 65 288 6.0E-125 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_0484 f5ab85cb2d48addb729210271f062ae5 391 SUPERFAMILY SSF53383 11 390 7.37E-89 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_0484 f5ab85cb2d48addb729210271f062ae5 391 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 13 390 1.0E-130 T 14-10-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8 Tharo_0484 f5ab85cb2d48addb729210271f062ae5 391 Pfam PF00155 Aminotransferase class I and II 35 384 4.8E-29 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Tharo_0484 f5ab85cb2d48addb729210271f062ae5 391 Gene3D G3DSA:3.90.1150.10 26 384 6.0E-125 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_2022 241bac6c6c5d0f8fc4096b3f00a32c07 75 SUPERFAMILY SSF46689 4 66 2.87E-22 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_2022 241bac6c6c5d0f8fc4096b3f00a32c07 75 Gene3D G3DSA:1.10.10.10 8 74 1.6E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2022 241bac6c6c5d0f8fc4096b3f00a32c07 75 Pfam PF04255 Protein of unknown function (DUF433) 9 64 3.8E-26 T 14-10-2018 IPR007367 Protein of unknown function DUF433 Tharo_3373 e7b980b6e5305b748f59d6b9d60662e4 300 SUPERFAMILY SSF46785 3 83 8.84E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_3373 e7b980b6e5305b748f59d6b9d60662e4 300 Pfam PF03466 LysR substrate binding domain 95 294 1.1E-21 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_3373 e7b980b6e5305b748f59d6b9d60662e4 300 Gene3D G3DSA:3.40.190.10 92 293 7.3E-69 T 14-10-2018 Tharo_3373 e7b980b6e5305b748f59d6b9d60662e4 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 5.8E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_3373 e7b980b6e5305b748f59d6b9d60662e4 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 5.8E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_3373 e7b980b6e5305b748f59d6b9d60662e4 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 5.8E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_3373 e7b980b6e5305b748f59d6b9d60662e4 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 2.2E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_3373 e7b980b6e5305b748f59d6b9d60662e4 300 Gene3D G3DSA:1.10.10.10 1 87 5.7E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_3373 e7b980b6e5305b748f59d6b9d60662e4 300 Gene3D G3DSA:3.40.190.10 171 269 7.3E-69 T 14-10-2018 Tharo_3373 e7b980b6e5305b748f59d6b9d60662e4 300 SUPERFAMILY SSF53850 90 297 1.49E-42 T 14-10-2018 Tharo_0595 550a9f4bb7ba01fd6058206f52c0ac28 350 Gene3D G3DSA:3.30.420.10 125 305 2.3E-10 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_0595 550a9f4bb7ba01fd6058206f52c0ac28 350 SUPERFAMILY SSF53098 128 291 7.08E-41 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_0595 550a9f4bb7ba01fd6058206f52c0ac28 350 Pfam PF00665 Integrase core domain 129 245 2.5E-19 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Tharo_0228 550a9f4bb7ba01fd6058206f52c0ac28 350 Gene3D G3DSA:3.30.420.10 125 305 2.3E-10 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_0228 550a9f4bb7ba01fd6058206f52c0ac28 350 SUPERFAMILY SSF53098 128 291 7.08E-41 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_0228 550a9f4bb7ba01fd6058206f52c0ac28 350 Pfam PF00665 Integrase core domain 129 245 2.5E-19 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Tharo_0206 550a9f4bb7ba01fd6058206f52c0ac28 350 Gene3D G3DSA:3.30.420.10 125 305 2.3E-10 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_0206 550a9f4bb7ba01fd6058206f52c0ac28 350 SUPERFAMILY SSF53098 128 291 7.08E-41 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_0206 550a9f4bb7ba01fd6058206f52c0ac28 350 Pfam PF00665 Integrase core domain 129 245 2.5E-19 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Tharo_0055 39ca40bc50d3eeaa619a33c88dfee52a 175 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 13 167 4.8E-55 T 14-10-2018 IPR023635 Peptide deformylase Tharo_0055 39ca40bc50d3eeaa619a33c88dfee52a 175 PIRSF PIRSF004749 2 174 2.5E-55 T 14-10-2018 IPR023635 Peptide deformylase Tharo_0055 39ca40bc50d3eeaa619a33c88dfee52a 175 SUPERFAMILY SSF56420 11 172 6.15E-62 T 14-10-2018 IPR036821 Peptide deformylase superfamily Tharo_0055 39ca40bc50d3eeaa619a33c88dfee52a 175 Pfam PF01327 Polypeptide deformylase 13 159 1.2E-50 T 14-10-2018 IPR023635 Peptide deformylase Tharo_0055 39ca40bc50d3eeaa619a33c88dfee52a 175 PRINTS PR01576 Peptide deformylase signature 41 70 1.8E-37 T 14-10-2018 IPR023635 Peptide deformylase Tharo_0055 39ca40bc50d3eeaa619a33c88dfee52a 175 PRINTS PR01576 Peptide deformylase signature 128 157 1.8E-37 T 14-10-2018 IPR023635 Peptide deformylase Tharo_0055 39ca40bc50d3eeaa619a33c88dfee52a 175 PRINTS PR01576 Peptide deformylase signature 97 108 1.8E-37 T 14-10-2018 IPR023635 Peptide deformylase Tharo_0055 39ca40bc50d3eeaa619a33c88dfee52a 175 PRINTS PR01576 Peptide deformylase signature 109 127 1.8E-37 T 14-10-2018 IPR023635 Peptide deformylase Tharo_0055 39ca40bc50d3eeaa619a33c88dfee52a 175 Gene3D G3DSA:3.90.45.10 2 175 1.7E-63 T 14-10-2018 IPR036821 Peptide deformylase superfamily Tharo_0055 39ca40bc50d3eeaa619a33c88dfee52a 175 Hamap MF_00163 Peptide deformylase [def]. 10 170 31.461 T 14-10-2018 IPR023635 Peptide deformylase Tharo_2481 9376164e33e569789dc2b927a06fa61c 197 Pfam PF02660 Glycerol-3-phosphate acyltransferase 10 184 6.8E-50 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 Tharo_2481 9376164e33e569789dc2b927a06fa61c 197 SMART SM01207 8 185 2.9E-81 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 Tharo_2481 9376164e33e569789dc2b927a06fa61c 197 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 5 193 19.781 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 Tharo_2481 9376164e33e569789dc2b927a06fa61c 197 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 4 192 1.3E-54 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 Tharo_2988 edb58244d328f4e35f9bf1105fad6ffe 260 SUPERFAMILY SSF52467 6 252 3.92E-69 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Tharo_2988 edb58244d328f4e35f9bf1105fad6ffe 260 Gene3D G3DSA:3.30.1600.10 34 173 1.3E-64 T 14-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily Tharo_2988 edb58244d328f4e35f9bf1105fad6ffe 260 Gene3D G3DSA:3.40.50.1220 16 248 1.3E-64 T 14-10-2018 Tharo_2988 edb58244d328f4e35f9bf1105fad6ffe 260 Pfam PF02146 Sir2 family 25 200 1.2E-41 T 14-10-2018 IPR003000 Sirtuin family GO:0070403 Tharo_1514 78dfb2903963d859cd1ad18682a08fb5 769 SMART SM01008 25 131 1.5E-45 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Tharo_1514 78dfb2903963d859cd1ad18682a08fb5 769 Gene3D G3DSA:3.30.365.10 370 758 6.9E-148 T 14-10-2018 Tharo_1514 78dfb2903963d859cd1ad18682a08fb5 769 TIGRFAM TIGR03194 4hydrxCoA_A: 4-hydroxybenzoyl-CoA reductase, alpha subunit 15 762 0.0 T 14-10-2018 IPR017607 4-hydroxybenzoyl-CoA reductase, alpha subunit KEGG: 00362+1.3.7.9|KEGG: 00627+1.3.7.9|MetaCyc: PWY-6080|MetaCyc: PWY-7046 Tharo_1514 78dfb2903963d859cd1ad18682a08fb5 769 Gene3D G3DSA:3.30.365.10 23 283 1.2E-132 T 14-10-2018 Tharo_1514 78dfb2903963d859cd1ad18682a08fb5 769 SUPERFAMILY SSF54665 6 154 1.31E-41 T 14-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily Tharo_1514 78dfb2903963d859cd1ad18682a08fb5 769 SUPERFAMILY SSF56003 135 764 8.5E-178 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 Tharo_1514 78dfb2903963d859cd1ad18682a08fb5 769 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 25 131 7.7E-32 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Tharo_1514 78dfb2903963d859cd1ad18682a08fb5 769 Gene3D G3DSA:3.90.1170.50 40 131 1.2E-132 T 14-10-2018 Tharo_1514 78dfb2903963d859cd1ad18682a08fb5 769 Gene3D G3DSA:3.30.365.10 447 619 6.9E-148 T 14-10-2018 Tharo_1514 78dfb2903963d859cd1ad18682a08fb5 769 Gene3D G3DSA:3.30.365.10 132 359 1.2E-132 T 14-10-2018 Tharo_1514 78dfb2903963d859cd1ad18682a08fb5 769 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 147 703 6.2E-151 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Tharo_1907 db2db6ee2159900da0d6c87e12149c4f 596 PIRSF PIRSF001327 1 595 4.8E-257 T 14-10-2018 IPR027541 Arsenical pump-driving ATPase GO:0005524|GO:0015446|GO:0016887|GO:0071722 MetaCyc: PWY-4621 Tharo_1907 db2db6ee2159900da0d6c87e12149c4f 596 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 12 291 1.2E-76 T 14-10-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 Tharo_1907 db2db6ee2159900da0d6c87e12149c4f 596 TIGRFAM TIGR04291 arsen_driv_ArsA: arsenical pump-driving ATPase 7 581 4.6E-267 T 14-10-2018 IPR027541 Arsenical pump-driving ATPase GO:0005524|GO:0015446|GO:0016887|GO:0071722 MetaCyc: PWY-4621 Tharo_1907 db2db6ee2159900da0d6c87e12149c4f 596 Pfam PF02374 Anion-transporting ATPase 337 484 8.4E-29 T 14-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 Tharo_1907 db2db6ee2159900da0d6c87e12149c4f 596 Pfam PF02374 Anion-transporting ATPase 9 291 5.9E-72 T 14-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 Tharo_1907 db2db6ee2159900da0d6c87e12149c4f 596 SUPERFAMILY SSF52540 5 285 3.77E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1907 db2db6ee2159900da0d6c87e12149c4f 596 Gene3D G3DSA:3.40.50.300 1 294 1.6E-83 T 14-10-2018 Tharo_1907 db2db6ee2159900da0d6c87e12149c4f 596 Gene3D G3DSA:3.40.50.300 319 592 6.1E-68 T 14-10-2018 Tharo_1907 db2db6ee2159900da0d6c87e12149c4f 596 SUPERFAMILY SSF52540 321 587 1.67E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1907 db2db6ee2159900da0d6c87e12149c4f 596 SMART SM00382 7 226 0.029 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1907 db2db6ee2159900da0d6c87e12149c4f 596 SMART SM00382 334 530 0.21 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2088 b7f108746f5ce129930f02843ba2494c 398 SUPERFAMILY SSF53383 5 378 2.13E-94 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_2088 b7f108746f5ce129930f02843ba2494c 398 PIRSF PIRSF005572 4 383 5.1E-121 T 14-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 Tharo_2088 b7f108746f5ce129930f02843ba2494c 398 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 197 216 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site Tharo_2088 b7f108746f5ce129930f02843ba2494c 398 Pfam PF00266 Aminotransferase class-V 6 368 3.4E-62 T 14-10-2018 IPR000192 Aminotransferase class V domain Tharo_2088 b7f108746f5ce129930f02843ba2494c 398 Gene3D G3DSA:1.10.260.50 17 282 8.4E-128 T 14-10-2018 Tharo_2088 b7f108746f5ce129930f02843ba2494c 398 Gene3D G3DSA:3.40.640.10 67 239 8.4E-128 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_2088 b7f108746f5ce129930f02843ba2494c 398 Gene3D G3DSA:3.90.1150.10 6 372 8.4E-128 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_2057 5a69e2ad98fcaacb79c9ce1d86e28483 344 SUPERFAMILY SSF51161 30 315 5.9E-80 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily Tharo_2057 5a69e2ad98fcaacb79c9ce1d86e28483 344 Gene3D G3DSA:2.160.10.10 97 307 7.0E-65 T 14-10-2018 Tharo_2057 5a69e2ad98fcaacb79c9ce1d86e28483 344 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 142 176 3.7E-9 T 14-10-2018 IPR001451 Hexapeptide repeat Tharo_2057 5a69e2ad98fcaacb79c9ce1d86e28483 344 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 220 255 7.3E-7 T 14-10-2018 IPR001451 Hexapeptide repeat Tharo_2057 5a69e2ad98fcaacb79c9ce1d86e28483 344 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 7 324 37.484 T 14-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 Tharo_2057 5a69e2ad98fcaacb79c9ce1d86e28483 344 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 6 327 4.8E-114 T 14-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 Tharo_2057 5a69e2ad98fcaacb79c9ce1d86e28483 344 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 21 88 5.3E-23 T 14-10-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 Tharo_2057 5a69e2ad98fcaacb79c9ce1d86e28483 344 Gene3D G3DSA:3.40.1390.10 1 96 3.8E-28 T 14-10-2018 Tharo_2057 5a69e2ad98fcaacb79c9ce1d86e28483 344 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 127 155 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 Tharo_2057 5a69e2ad98fcaacb79c9ce1d86e28483 344 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 257 290 4.5E-7 T 14-10-2018 IPR001451 Hexapeptide repeat Tharo_2057 5a69e2ad98fcaacb79c9ce1d86e28483 344 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 115 139 7.2E-4 T 14-10-2018 IPR001451 Hexapeptide repeat Tharo_2235 c0f33cead3f6e9d5f9d29de7cefddc28 697 Pfam PF03958 Bacterial type II/III secretion system short domain 259 350 7.4E-8 T 14-10-2018 IPR005644 NolW-like Tharo_2235 c0f33cead3f6e9d5f9d29de7cefddc28 697 Pfam PF03958 Bacterial type II/III secretion system short domain 360 475 3.5E-9 T 14-10-2018 IPR005644 NolW-like Tharo_2235 c0f33cead3f6e9d5f9d29de7cefddc28 697 Pfam PF00263 Bacterial type II and III secretion system protein 545 684 1.4E-39 T 14-10-2018 IPR004846 Type II/III secretion system GO:0009306 Tharo_2235 c0f33cead3f6e9d5f9d29de7cefddc28 697 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 97 684 1.6E-114 T 14-10-2018 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 Tharo_2235 c0f33cead3f6e9d5f9d29de7cefddc28 697 Gene3D G3DSA:3.30.1370.120 257 350 7.3E-8 T 14-10-2018 IPR038591 NolW-like superfamily Tharo_2235 c0f33cead3f6e9d5f9d29de7cefddc28 697 Gene3D G3DSA:3.30.1370.120 94 249 1.9E-18 T 14-10-2018 IPR038591 NolW-like superfamily Tharo_2235 c0f33cead3f6e9d5f9d29de7cefddc28 697 PRINTS PR00811 Bacterial general secretion pathway protein D signature 475 485 2.2E-11 T 14-10-2018 IPR001775 GspD/PilQ family Tharo_2235 c0f33cead3f6e9d5f9d29de7cefddc28 697 PRINTS PR00811 Bacterial general secretion pathway protein D signature 541 565 2.2E-11 T 14-10-2018 IPR001775 GspD/PilQ family Tharo_2235 c0f33cead3f6e9d5f9d29de7cefddc28 697 PRINTS PR00811 Bacterial general secretion pathway protein D signature 671 689 2.2E-11 T 14-10-2018 IPR001775 GspD/PilQ family Tharo_0363 5ffde54ccad77595b745db54168b47df 95 Pfam PF09907 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system 19 90 1.2E-27 T 14-10-2018 IPR018669 Toxin-antitoxin system, toxin component, HigB, putative GO:0016788 Tharo_2751 809ace9177576a6cdd2435f93f6e4ea2 450 Pfam PF00437 Type II/IV secretion system protein 97 373 9.4E-84 T 14-10-2018 IPR001482 Type II/IV secretion system protein Tharo_2751 809ace9177576a6cdd2435f93f6e4ea2 450 Gene3D G3DSA:3.40.50.300 194 429 1.9E-70 T 14-10-2018 Tharo_2751 809ace9177576a6cdd2435f93f6e4ea2 450 SUPERFAMILY SSF52540 78 409 2.96E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2751 809ace9177576a6cdd2435f93f6e4ea2 450 Gene3D G3DSA:3.30.450.380 17 192 2.8E-49 T 14-10-2018 Tharo_2112 340c935a515b49b63bb0183ebeb0fc38 755 Gene3D G3DSA:2.60.40.10 202 320 3.4E-6 T 14-10-2018 IPR013783 Immunoglobulin-like fold Tharo_0831 50a011a4fd1a229d385a3e2194051df2 1565 Gene3D G3DSA:2.160.20.60 1262 1560 1.7E-112 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 Tharo_0831 50a011a4fd1a229d385a3e2194051df2 1565 Gene3D G3DSA:3.20.20.70 802 1255 4.7E-207 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_0831 50a011a4fd1a229d385a3e2194051df2 1565 Gene3D G3DSA:3.20.20.70 457 801 2.7E-122 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_0831 50a011a4fd1a229d385a3e2194051df2 1565 Pfam PF04898 Glutamate synthase central domain 475 758 2.3E-111 T 14-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 Tharo_0831 50a011a4fd1a229d385a3e2194051df2 1565 Gene3D G3DSA:3.60.20.10 19 453 5.7E-183 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Tharo_0831 50a011a4fd1a229d385a3e2194051df2 1565 SUPERFAMILY SSF56235 19 444 7.82E-156 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Tharo_0831 50a011a4fd1a229d385a3e2194051df2 1565 SUPERFAMILY SSF69336 1258 1550 1.29E-95 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 Tharo_0831 50a011a4fd1a229d385a3e2194051df2 1565 Pfam PF01645 Conserved region in glutamate synthase 819 1209 1.7E-156 T 14-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 Tharo_0831 50a011a4fd1a229d385a3e2194051df2 1565 Pfam PF00310 Glutamine amidotransferases class-II 19 442 3.6E-187 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain Tharo_0831 50a011a4fd1a229d385a3e2194051df2 1565 SUPERFAMILY SSF51395 471 1254 2.73E-265 T 14-10-2018 Tharo_0831 50a011a4fd1a229d385a3e2194051df2 1565 Pfam PF01493 GXGXG motif 1289 1473 2.1E-83 T 14-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 Tharo_2781 25fd069d3dcbe5f333e17927deffd65b 447 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 15 396 4.6E-106 T 14-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 Tharo_2781 25fd069d3dcbe5f333e17927deffd65b 447 Gene3D G3DSA:3.40.1670.10 309 419 9.1E-22 T 14-10-2018 Tharo_2781 25fd069d3dcbe5f333e17927deffd65b 447 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 419 1.1E-90 T 14-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 Tharo_2781 25fd069d3dcbe5f333e17927deffd65b 447 SUPERFAMILY SSF143968 294 444 9.15E-28 T 14-10-2018 Tharo_2781 25fd069d3dcbe5f333e17927deffd65b 447 SUPERFAMILY SSF50475 3 293 5.89E-75 T 14-10-2018 Tharo_0511 850c2a481b9df52791857da09411c84b 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 1.5E-17 T 14-10-2018 Tharo_0511 850c2a481b9df52791857da09411c84b 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 306 1.5E-17 T 14-10-2018 Tharo_0511 850c2a481b9df52791857da09411c84b 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 275 290 1.5E-17 T 14-10-2018 Tharo_0511 850c2a481b9df52791857da09411c84b 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.5E-17 T 14-10-2018 Tharo_0511 850c2a481b9df52791857da09411c84b 387 SUPERFAMILY SSF51905 2 379 7.41E-55 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_0511 850c2a481b9df52791857da09411c84b 387 Pfam PF01494 FAD binding domain 3 333 1.0E-22 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 Tharo_0511 850c2a481b9df52791857da09411c84b 387 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 4 383 1.0E-116 T 14-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 Tharo_0511 850c2a481b9df52791857da09411c84b 387 Gene3D G3DSA:3.30.9.50 76 264 7.4E-96 T 14-10-2018 Tharo_0511 850c2a481b9df52791857da09411c84b 387 Gene3D G3DSA:3.50.50.60 4 332 7.4E-96 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_2029 3b4f854c11e4e596015d8a609e5e1f7e 227 Gene3D G3DSA:3.40.50.300 1 222 1.1E-59 T 14-10-2018 Tharo_2029 3b4f854c11e4e596015d8a609e5e1f7e 227 Pfam PF00005 ABC transporter 21 168 2.4E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_2029 3b4f854c11e4e596015d8a609e5e1f7e 227 SMART SM00382 29 218 8.9E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2029 3b4f854c11e4e596015d8a609e5e1f7e 227 SUPERFAMILY SSF52540 17 214 1.47E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2029 3b4f854c11e4e596015d8a609e5e1f7e 227 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_2712 729e25f2b20f023dbba23346688b048d 179 Gene3D G3DSA:3.30.1440.10 1 179 2.5E-79 T 14-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2712 729e25f2b20f023dbba23346688b048d 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 3.1E-40 T 14-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2712 729e25f2b20f023dbba23346688b048d 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 14-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2712 729e25f2b20f023dbba23346688b048d 179 PIRSF PIRSF002161 1 179 3.4E-65 T 14-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2712 729e25f2b20f023dbba23346688b048d 179 SUPERFAMILY SSF55282 3 179 3.77E-78 T 14-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2712 729e25f2b20f023dbba23346688b048d 179 Pfam PF00281 Ribosomal protein L5 24 80 5.4E-28 T 14-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2712 729e25f2b20f023dbba23346688b048d 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 44.304 T 14-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_0757 fa0688616f03aa028d8a580e178207ed 290 Pfam PF02104 SURF1 family 22 261 5.3E-32 T 14-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_3165 b76e68f26e89878327ad7265d67604e3 201 Pfam PF01205 Uncharacterized protein family UPF0029 16 118 1.0E-25 T 14-10-2018 IPR001498 Impact, N-terminal Tharo_3165 b76e68f26e89878327ad7265d67604e3 201 SUPERFAMILY SSF54980 130 194 2.88E-8 T 14-10-2018 IPR035647 EF-G domain III/V-like Tharo_3165 b76e68f26e89878327ad7265d67604e3 201 Gene3D G3DSA:3.30.230.30 2 125 8.9E-44 T 14-10-2018 IPR036956 Impact, N-terminal domain superfamily Tharo_3165 b76e68f26e89878327ad7265d67604e3 201 Pfam PF09186 Domain of unknown function (DUF1949) 134 189 3.7E-10 T 14-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal Tharo_3165 b76e68f26e89878327ad7265d67604e3 201 SUPERFAMILY SSF54211 3 125 1.48E-37 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_0703 9346f254b6ee2c5814da25bafae1a7a2 119 TIGRFAM TIGR03745 conj_TIGR03745: integrating conjugative element membrane protein, PFL_4702 family 16 119 1.5E-44 T 14-10-2018 IPR021356 Integrating conjugative element protein PFL4702 Tharo_0703 9346f254b6ee2c5814da25bafae1a7a2 119 Pfam PF11190 Protein of unknown function (DUF2976) 32 118 1.3E-32 T 14-10-2018 IPR021356 Integrating conjugative element protein PFL4702 Tharo_0804 f96cc9033f969a9977ac484266a8abeb 266 SUPERFAMILY SSF52096 3 264 2.93E-79 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_0804 f96cc9033f969a9977ac484266a8abeb 266 Gene3D G3DSA:3.90.226.10 2 206 1.6E-62 T 14-10-2018 Tharo_0804 f96cc9033f969a9977ac484266a8abeb 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 264 6.9E-53 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Tharo_0804 f96cc9033f969a9977ac484266a8abeb 266 Gene3D G3DSA:1.10.12.10 209 264 7.6E-16 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal Tharo_2677 8dfde454aa746ac04652943cbd4f1c2f 240 SMART SM01007 16 202 8.7E-61 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal Tharo_2677 8dfde454aa746ac04652943cbd4f1c2f 240 Gene3D G3DSA:3.40.225.10 11 232 2.6E-64 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily Tharo_2677 8dfde454aa746ac04652943cbd4f1c2f 240 SUPERFAMILY SSF53639 8 230 1.75E-61 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily Tharo_2677 8dfde454aa746ac04652943cbd4f1c2f 240 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 18 202 2.5E-48 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal Tharo_3055 282f6571681b0527cebabb80c005cc8a 172 SUPERFAMILY SSF52949 3 167 1.28E-61 T 14-10-2018 Tharo_3055 282f6571681b0527cebabb80c005cc8a 172 Gene3D G3DSA:3.40.220.10 3 171 3.3E-71 T 14-10-2018 Tharo_3055 282f6571681b0527cebabb80c005cc8a 172 Pfam PF01661 Macro domain 21 133 1.0E-42 T 14-10-2018 IPR002589 Macro domain Tharo_3055 282f6571681b0527cebabb80c005cc8a 172 SMART SM00506 4 133 1.2E-43 T 14-10-2018 IPR002589 Macro domain Tharo_0361 9440e7a666e251bd1fd91c29e2d1e8cd 89 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 38 75 9.7E-15 T 14-10-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 Tharo_0361 9440e7a666e251bd1fd91c29e2d1e8cd 89 SUPERFAMILY SSF47413 39 81 7.31E-9 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_0361 9440e7a666e251bd1fd91c29e2d1e8cd 89 Gene3D G3DSA:1.10.260.40 36 75 5.1E-13 T 14-10-2018 Tharo_2141 1fdd793142688659ca5671e26478310a 112 Gene3D G3DSA:3.90.75.20 1 34 5.4E-9 T 14-10-2018 Tharo_2141 1fdd793142688659ca5671e26478310a 112 SUPERFAMILY SSF64496 46 103 2.88E-8 T 14-10-2018 Tharo_2141 1fdd793142688659ca5671e26478310a 112 Gene3D G3DSA:1.10.10.10 44 106 2.7E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2141 1fdd793142688659ca5671e26478310a 112 Pfam PF13392 HNH endonuclease 1 26 6.3E-8 T 14-10-2018 IPR003615 HNH nuclease Tharo_2141 1fdd793142688659ca5671e26478310a 112 SUPERFAMILY SSF54060 1 30 6.59E-8 T 14-10-2018 Tharo_0952 cdfb09ea9325eeeeb7f4ebaa0516e441 77 Pfam PF13560 Helix-turn-helix domain 20 67 2.4E-6 T 14-10-2018 Tharo_0952 cdfb09ea9325eeeeb7f4ebaa0516e441 77 Gene3D G3DSA:1.10.260.40 17 76 5.4E-18 T 14-10-2018 Tharo_0952 cdfb09ea9325eeeeb7f4ebaa0516e441 77 SUPERFAMILY SSF47413 19 62 2.56E-9 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_0952 cdfb09ea9325eeeeb7f4ebaa0516e441 77 SMART SM00530 18 72 0.0081 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_0327 b26c860dc5d09b4f266ba339960bcf1d 149 Gene3D G3DSA:1.20.58.300 1 124 2.2E-19 T 14-10-2018 Tharo_0327 b26c860dc5d09b4f266ba339960bcf1d 149 SUPERFAMILY SSF140566 3 124 1.44E-13 T 14-10-2018 IPR036679 FlgN-like superfamily GO:0005515|GO:0044780 Tharo_0327 b26c860dc5d09b4f266ba339960bcf1d 149 Pfam PF05130 FlgN protein 3 137 2.3E-22 T 14-10-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 Tharo_3010 42467a5a8f752d4039ce5472137632bc 320 SMART SM00849 34 223 4.6E-14 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_3010 42467a5a8f752d4039ce5472137632bc 320 Pfam PF00753 Metallo-beta-lactamase superfamily 34 214 2.6E-9 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_3010 42467a5a8f752d4039ce5472137632bc 320 SUPERFAMILY SSF56281 15 311 4.9E-54 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_3010 42467a5a8f752d4039ce5472137632bc 320 Gene3D G3DSA:3.60.15.10 12 242 6.2E-44 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_0314 4410e60591f774f2be7f29a4ba080798 153 SUPERFAMILY SSF52540 19 98 3.05E-7 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0314 4410e60591f774f2be7f29a4ba080798 153 Gene3D G3DSA:3.40.50.300 2 88 5.1E-5 T 14-10-2018 Tharo_1340 b3e96607761eaa85139775508b9d87e6 642 SMART SM00487 39 237 1.1E-61 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Tharo_1340 b3e96607761eaa85139775508b9d87e6 642 Gene3D G3DSA:3.40.50.300 229 441 2.0E-50 T 14-10-2018 Tharo_1340 b3e96607761eaa85139775508b9d87e6 642 Pfam PF03880 DbpA RNA binding domain 509 579 1.9E-21 T 14-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain Tharo_1340 b3e96607761eaa85139775508b9d87e6 642 Pfam PF00271 Helicase conserved C-terminal domain 245 355 8.0E-30 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_1340 b3e96607761eaa85139775508b9d87e6 642 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 168 176 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site Tharo_1340 b3e96607761eaa85139775508b9d87e6 642 Gene3D G3DSA:3.40.50.300 8 225 1.8E-74 T 14-10-2018 Tharo_1340 b3e96607761eaa85139775508b9d87e6 642 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 15 581 44.258 T 14-10-2018 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 Tharo_1340 b3e96607761eaa85139775508b9d87e6 642 Gene3D G3DSA:3.30.70.330 508 581 4.3E-12 T 14-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily Tharo_1340 b3e96607761eaa85139775508b9d87e6 642 Pfam PF00270 DEAD/DEAH box helicase 45 208 3.3E-48 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Tharo_1340 b3e96607761eaa85139775508b9d87e6 642 SUPERFAMILY SSF52540 88 377 4.49E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1340 b3e96607761eaa85139775508b9d87e6 642 SMART SM00490 274 355 2.2E-34 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_3454 5e3d8c6881456b2b6bbdda6a1de54906 129 ProDom PD031251 TRAK PLASMID ORIT BINDING TRANSFER SYSTEM DNA ORIT-BINDING SEQUENCING DIRECT 1 73 8.0E-30 T 14-10-2018 IPR035225 Protein of unknown function DUF5338 Tharo_3454 5e3d8c6881456b2b6bbdda6a1de54906 129 Pfam PF17273 Family of unknown function (DUF5338) 3 72 3.1E-26 T 14-10-2018 IPR035225 Protein of unknown function DUF5338 Tharo_2123 1289bff1fedc50d54274f5d8027eefa7 181 Gene3D G3DSA:1.10.10.1400 1 64 2.1E-23 T 14-10-2018 IPR038713 Terminase small subunit, N-terminal domain superfamily Tharo_2123 1289bff1fedc50d54274f5d8027eefa7 181 Pfam PF03592 Terminase small subunit 4 153 3.5E-33 T 14-10-2018 IPR005335 Terminase small subunit GO:0006323 Tharo_0451 c6f338de3a2264ca8cf5968031c85249 319 Pfam PF03186 CobD/Cbib protein 13 289 4.8E-87 T 14-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 Tharo_0451 c6f338de3a2264ca8cf5968031c85249 319 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 310 99.549 T 14-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 Tharo_2952 00c8c5c277bd72155dff51565a2c179a 367 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 47 365 3.6E-97 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family Tharo_2952 00c8c5c277bd72155dff51565a2c179a 367 Pfam PF16868 NMT1-like family 76 365 2.4E-89 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family Tharo_2952 00c8c5c277bd72155dff51565a2c179a 367 SUPERFAMILY SSF53850 71 367 1.59E-82 T 14-10-2018 Tharo_2952 00c8c5c277bd72155dff51565a2c179a 367 Gene3D G3DSA:3.40.190.10 163 301 9.0E-98 T 14-10-2018 Tharo_2952 00c8c5c277bd72155dff51565a2c179a 367 Gene3D G3DSA:3.40.190.10 76 365 9.0E-98 T 14-10-2018 Tharo_2908 e1e8e2f05b35bdabb24e86f8a4f7762a 483 Gene3D G3DSA:3.40.605.10 3 253 4.9E-72 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Tharo_2908 e1e8e2f05b35bdabb24e86f8a4f7762a 483 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 Tharo_2908 e1e8e2f05b35bdabb24e86f8a4f7762a 483 Gene3D G3DSA:3.40.309.10 254 483 8.2E-76 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Tharo_2908 e1e8e2f05b35bdabb24e86f8a4f7762a 483 Pfam PF00171 Aldehyde dehydrogenase family 17 472 1.1E-141 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Tharo_2908 e1e8e2f05b35bdabb24e86f8a4f7762a 483 SUPERFAMILY SSF53720 3 476 3.01E-146 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Tharo_2511 2a11ce7077836b98504cb8a649bbe25d 83 ProSitePatterns PS00732 Ribosomal protein S16 signature. 2 11 - T 14-10-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2511 2a11ce7077836b98504cb8a649bbe25d 83 Gene3D G3DSA:3.30.1320.10 1 82 9.8E-31 T 14-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2511 2a11ce7077836b98504cb8a649bbe25d 83 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 79 2.2E-27 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2511 2a11ce7077836b98504cb8a649bbe25d 83 Pfam PF00886 Ribosomal protein S16 8 68 1.5E-23 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2511 2a11ce7077836b98504cb8a649bbe25d 83 SUPERFAMILY SSF54565 1 77 5.76E-29 T 14-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2511 2a11ce7077836b98504cb8a649bbe25d 83 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 23.407 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2664 f8815736dbad857e22dc427208f0a728 640 PIRSF PIRSF000549 1 640 3.3E-292 T 14-10-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 Tharo_2664 f8815736dbad857e22dc427208f0a728 640 Pfam PF08298 PrkA AAA domain 19 376 8.6E-175 T 14-10-2018 IPR013153 PrkA AAA domain Tharo_2664 f8815736dbad857e22dc427208f0a728 640 SUPERFAMILY SSF52540 75 345 7.65E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2664 f8815736dbad857e22dc427208f0a728 640 SMART SM00763 19 376 1.5E-217 T 14-10-2018 IPR013153 PrkA AAA domain Tharo_2664 f8815736dbad857e22dc427208f0a728 640 Pfam PF06798 PrkA serine protein kinase C-terminal domain 379 632 1.6E-74 T 14-10-2018 IPR010650 PrkA C-terminal domain Tharo_3079 1dd54f234f6e7f2843b22f4d84c5e349 523 SUPERFAMILY SSF51338 29 521 1.23E-17 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Tharo_3079 1dd54f234f6e7f2843b22f4d84c5e349 523 Gene3D G3DSA:2.30.40.10 29 494 3.3E-87 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Tharo_3079 1dd54f234f6e7f2843b22f4d84c5e349 523 SUPERFAMILY SSF51556 66 481 9.26E-30 T 14-10-2018 IPR032466 Metal-dependent hydrolase Tharo_3079 1dd54f234f6e7f2843b22f4d84c5e349 523 Gene3D G3DSA:3.20.20.140 67 480 3.3E-87 T 14-10-2018 Tharo_3079 1dd54f234f6e7f2843b22f4d84c5e349 523 Gene3D G3DSA:3.10.310.70 85 197 3.3E-87 T 14-10-2018 Tharo_3079 1dd54f234f6e7f2843b22f4d84c5e349 523 Pfam PF07969 Amidohydrolase family 56 520 3.4E-62 T 14-10-2018 IPR013108 Amidohydrolase 3 Tharo_3087 474e0eaf230361dcf4aa55fef4eab454 248 SUPERFAMILY SSF51735 4 245 2.69E-87 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_3087 474e0eaf230361dcf4aa55fef4eab454 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 242 3.1E-66 T 14-10-2018 Tharo_3087 474e0eaf230361dcf4aa55fef4eab454 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Tharo_3087 474e0eaf230361dcf4aa55fef4eab454 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.9E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3087 474e0eaf230361dcf4aa55fef4eab454 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.9E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3087 474e0eaf230361dcf4aa55fef4eab454 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.9E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3087 474e0eaf230361dcf4aa55fef4eab454 248 Gene3D G3DSA:3.40.50.720 2 246 3.1E-86 T 14-10-2018 Tharo_3087 474e0eaf230361dcf4aa55fef4eab454 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.8E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3087 474e0eaf230361dcf4aa55fef4eab454 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 4.8E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3087 474e0eaf230361dcf4aa55fef4eab454 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 4.8E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3087 474e0eaf230361dcf4aa55fef4eab454 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.8E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3087 474e0eaf230361dcf4aa55fef4eab454 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.8E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_3087 474e0eaf230361dcf4aa55fef4eab454 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 4.8E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0201 360ab73acaf6421579829d285a09b42e 668 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 35 90 4.3E-9 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 Tharo_0201 360ab73acaf6421579829d285a09b42e 668 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 8 652 4.7E-273 T 14-10-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 Tharo_0201 360ab73acaf6421579829d285a09b42e 668 Pfam PF00501 AMP-binding enzyme 100 522 8.1E-46 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Tharo_0201 360ab73acaf6421579829d285a09b42e 668 Gene3D G3DSA:3.40.50.12780 73 518 3.2E-57 T 14-10-2018 Tharo_0201 360ab73acaf6421579829d285a09b42e 668 Gene3D G3DSA:3.30.300.30 522 649 7.4E-14 T 14-10-2018 Tharo_0201 360ab73acaf6421579829d285a09b42e 668 ProSitePatterns PS00455 Putative AMP-binding domain signature. 266 277 - T 14-10-2018 IPR020845 AMP-binding, conserved site Tharo_0201 360ab73acaf6421579829d285a09b42e 668 SUPERFAMILY SSF56801 27 642 6.28E-122 T 14-10-2018 Tharo_0631 f5a9765c763c55f65849dfe49b44f2cc 85 Pfam PF01722 BolA-like protein 25 75 7.1E-15 T 14-10-2018 IPR002634 BolA protein Tharo_0631 f5a9765c763c55f65849dfe49b44f2cc 85 PIRSF PIRSF003113 1 83 9.1E-22 T 14-10-2018 IPR002634 BolA protein Tharo_0631 f5a9765c763c55f65849dfe49b44f2cc 85 SUPERFAMILY SSF82657 2 80 6.67E-25 T 14-10-2018 IPR036065 BolA-like superfamily Tharo_0631 f5a9765c763c55f65849dfe49b44f2cc 85 Gene3D G3DSA:3.30.300.90 2 75 1.9E-25 T 14-10-2018 Tharo_2350 df6a1935f61c5e01531962d1355bd68c 1294 Pfam PF13502 AsmA-like C-terminal region 1034 1276 7.4E-63 T 14-10-2018 IPR032712 AsmA-like, C-terminal Tharo_2350 df6a1935f61c5e01531962d1355bd68c 1294 Pfam PF13116 Protein of unknown function 521 792 1.0E-61 T 14-10-2018 IPR025263 Domain of unknown function DUF3971 Tharo_2350 df6a1935f61c5e01531962d1355bd68c 1294 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 8 1278 7.6E-234 T 14-10-2018 IPR011836 Conserved hypothetical protein CHP02099 Tharo_1949 0438d55aafb3a6d4a4bd0dbb9b949358 373 SUPERFAMILY SSF102114 52 328 9.81E-40 T 14-10-2018 Tharo_1949 0438d55aafb3a6d4a4bd0dbb9b949358 373 Pfam PF04055 Radical SAM superfamily 92 243 2.4E-14 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_1949 0438d55aafb3a6d4a4bd0dbb9b949358 373 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 17 369 2.0E-188 T 14-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme Tharo_1949 0438d55aafb3a6d4a4bd0dbb9b949358 373 PIRSF PIRSF004869 8 325 7.3E-90 T 14-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted Tharo_1949 0438d55aafb3a6d4a4bd0dbb9b949358 373 Gene3D G3DSA:3.20.20.70 75 298 8.9E-34 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_0734 f260c080c0887399bcfc9f830bb03e76 146 Gene3D G3DSA:2.40.50.140 3 145 6.8E-21 T 14-10-2018 Tharo_0734 f260c080c0887399bcfc9f830bb03e76 146 Pfam PF00436 Single-strand binding protein family 9 109 1.3E-11 T 14-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 Tharo_0734 f260c080c0887399bcfc9f830bb03e76 146 SUPERFAMILY SSF50249 2 138 1.71E-24 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_0734 f260c080c0887399bcfc9f830bb03e76 146 PIRSF PIRSF002070 1 146 6.9E-24 T 14-10-2018 Tharo_1763 d18d1456ca793eec69b74ded83e93d74 459 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 196 252 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_1763 d18d1456ca793eec69b74ded83e93d74 459 SUPERFAMILY SSF81442 4 449 7.06E-87 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_1763 d18d1456ca793eec69b74ded83e93d74 459 Gene3D G3DSA:1.20.210.10 1 458 5.4E-124 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_1763 d18d1456ca793eec69b74ded83e93d74 459 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 8 436 1.3E-80 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0884 52e65eec728ca98e8a64067fb8a84063 110 SUPERFAMILY SSF81301 18 104 2.84E-14 T 14-10-2018 Tharo_0884 52e65eec728ca98e8a64067fb8a84063 110 Gene3D G3DSA:3.30.460.10 2 104 2.4E-14 T 14-10-2018 Tharo_0884 52e65eec728ca98e8a64067fb8a84063 110 Pfam PF01909 Nucleotidyltransferase domain 23 60 7.6E-9 T 14-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Tharo_2497 1938939872833e9c9c22a615fa0ebc20 275 SUPERFAMILY SSF52374 1 275 3.75E-96 T 14-10-2018 Tharo_2497 1938939872833e9c9c22a615fa0ebc20 275 Gene3D G3DSA:3.30.1300.10 175 273 1.3E-31 T 14-10-2018 Tharo_2497 1938939872833e9c9c22a615fa0ebc20 275 Hamap MF_00158 Pantothenate synthetase [panC]. 2 275 37.278 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 Tharo_2497 1938939872833e9c9c22a615fa0ebc20 275 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 274 3.9E-86 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 Tharo_2497 1938939872833e9c9c22a615fa0ebc20 275 Pfam PF02569 Pantoate-beta-alanine ligase 3 273 4.1E-93 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 Tharo_2497 1938939872833e9c9c22a615fa0ebc20 275 Gene3D G3DSA:3.40.50.620 2 174 4.2E-67 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_0435 8ba0ae08f35def8ce6e729fa6aaa9b6c 105 Pfam PF01906 Putative heavy-metal-binding 1 105 1.3E-38 T 14-10-2018 IPR002765 Uncharacterised protein family UPF0145 Tharo_0435 8ba0ae08f35def8ce6e729fa6aaa9b6c 105 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 105 24.261 T 14-10-2018 IPR002765 Uncharacterised protein family UPF0145 Tharo_0435 8ba0ae08f35def8ce6e729fa6aaa9b6c 105 SUPERFAMILY SSF117782 1 105 1.44E-36 T 14-10-2018 IPR035439 UPF0145 domain superfamily Tharo_0435 8ba0ae08f35def8ce6e729fa6aaa9b6c 105 Gene3D G3DSA:3.30.110.70 2 105 1.6E-40 T 14-10-2018 Tharo_2359 16534d8424759068eabf8bab818bcd8b 306 Gene3D G3DSA:3.30.470.10 2 129 9.0E-41 T 14-10-2018 Tharo_2359 16534d8424759068eabf8bab818bcd8b 306 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 11 306 3.6E-135 T 14-10-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 Tharo_2359 16534d8424759068eabf8bab818bcd8b 306 Gene3D G3DSA:3.20.10.10 130 295 1.8E-50 T 14-10-2018 Tharo_2359 16534d8424759068eabf8bab818bcd8b 306 Pfam PF01063 Amino-transferase class IV 36 266 8.3E-51 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 Tharo_2359 16534d8424759068eabf8bab818bcd8b 306 SUPERFAMILY SSF56752 1 303 6.8E-99 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 Tharo_0786 0e51a1f0a949ab60a7492b9d1e66f23d 184 PIRSF PIRSF030820 1 178 9.2E-50 T 14-10-2018 IPR008318 Uncharacterised conserved protein UCP030820 Tharo_0786 0e51a1f0a949ab60a7492b9d1e66f23d 184 Pfam PF06073 Bacterial protein of unknown function (DUF934) 61 171 5.7E-39 T 14-10-2018 IPR008318 Uncharacterised conserved protein UCP030820 Tharo_2533 a0cce178ac995dd176b694f5523d30e6 947 SUPERFAMILY SSF158472 343 391 4.05E-7 T 14-10-2018 Tharo_2533 a0cce178ac995dd176b694f5523d30e6 947 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 763 886 5.2E-8 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2533 a0cce178ac995dd176b694f5523d30e6 947 Gene3D G3DSA:3.30.450.20 402 543 1.5E-7 T 14-10-2018 Tharo_2533 a0cce178ac995dd176b694f5523d30e6 947 SUPERFAMILY SSF47226 553 646 4.45E-14 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 Tharo_2533 a0cce178ac995dd176b694f5523d30e6 947 PRINTS PR00344 Bacterial sensor protein C-terminal signature 859 877 2.7E-5 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2533 a0cce178ac995dd176b694f5523d30e6 947 PRINTS PR00344 Bacterial sensor protein C-terminal signature 843 853 2.7E-5 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2533 a0cce178ac995dd176b694f5523d30e6 947 PRINTS PR00344 Bacterial sensor protein C-terminal signature 803 817 2.7E-5 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_2533 a0cce178ac995dd176b694f5523d30e6 947 SUPERFAMILY SSF55874 719 883 1.92E-22 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2533 a0cce178ac995dd176b694f5523d30e6 947 Gene3D G3DSA:3.30.565.10 714 894 4.3E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_2533 a0cce178ac995dd176b694f5523d30e6 947 SUPERFAMILY SSF55785 392 526 7.21E-5 T 14-10-2018 IPR035965 PAS domain superfamily Tharo_2533 a0cce178ac995dd176b694f5523d30e6 947 Pfam PF00672 HAMP domain 343 390 3.5E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_2533 a0cce178ac995dd176b694f5523d30e6 947 SMART SM00387 758 913 4.5E-11 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_2533 a0cce178ac995dd176b694f5523d30e6 947 Gene3D G3DSA:1.20.1480.50 307 401 2.5E-9 T 14-10-2018 Tharo_2533 a0cce178ac995dd176b694f5523d30e6 947 Pfam PF01627 Hpt domain 557 646 7.6E-9 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Tharo_2533 a0cce178ac995dd176b694f5523d30e6 947 SMART SM00073 552 649 3.5E-9 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Tharo_2533 a0cce178ac995dd176b694f5523d30e6 947 Gene3D G3DSA:1.20.120.160 548 658 9.0E-14 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 Tharo_2533 a0cce178ac995dd176b694f5523d30e6 947 SMART SM00304 342 394 3.2E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_1563 b2abd10c94e2387e5360c472c033959f 110 SUPERFAMILY SSF160113 55 108 1.3E-11 T 14-10-2018 IPR036913 YegP-like superfamily Tharo_1563 b2abd10c94e2387e5360c472c033959f 110 SUPERFAMILY SSF160113 4 60 6.8E-17 T 14-10-2018 IPR036913 YegP-like superfamily Tharo_1563 b2abd10c94e2387e5360c472c033959f 110 Gene3D G3DSA:2.30.29.80 1 110 7.5E-38 T 14-10-2018 Tharo_1563 b2abd10c94e2387e5360c472c033959f 110 Pfam PF07411 Domain of unknown function (DUF1508) 12 57 3.8E-16 T 14-10-2018 IPR010879 Domain of unknown function DUF1508 Tharo_1563 b2abd10c94e2387e5360c472c033959f 110 Pfam PF07411 Domain of unknown function (DUF1508) 61 108 9.8E-15 T 14-10-2018 IPR010879 Domain of unknown function DUF1508 Tharo_2365 88c41c3e3ca81dade548d68a41fc4e4f 877 SMART SM00863 656 698 2.6E-20 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Tharo_2365 88c41c3e3ca81dade548d68a41fc4e4f 877 SUPERFAMILY SSF50447 457 555 1.09E-15 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Tharo_2365 88c41c3e3ca81dade548d68a41fc4e4f 877 Gene3D G3DSA:2.40.30.130 469 555 5.5E-9 T 14-10-2018 Tharo_2365 88c41c3e3ca81dade548d68a41fc4e4f 877 Gene3D G3DSA:3.30.930.10 1 248 1.2E-121 T 14-10-2018 Tharo_2365 88c41c3e3ca81dade548d68a41fc4e4f 877 Pfam PF01411 tRNA synthetases class II (A) 5 557 4.0E-219 T 14-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 Tharo_2365 88c41c3e3ca81dade548d68a41fc4e4f 877 Pfam PF02272 DHHA1 domain 738 873 2.5E-27 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 Tharo_2365 88c41c3e3ca81dade548d68a41fc4e4f 877 SUPERFAMILY SSF55186 555 713 7.06E-48 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 Tharo_2365 88c41c3e3ca81dade548d68a41fc4e4f 877 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 656 698 6.3E-18 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Tharo_2365 88c41c3e3ca81dade548d68a41fc4e4f 877 SUPERFAMILY SSF55681 2 251 1.49E-109 T 14-10-2018 Tharo_2365 88c41c3e3ca81dade548d68a41fc4e4f 877 SUPERFAMILY SSF101353 252 449 1.83E-58 T 14-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 Tharo_2365 88c41c3e3ca81dade548d68a41fc4e4f 877 Gene3D G3DSA:3.10.310.40 766 874 2.2E-32 T 14-10-2018 Tharo_2365 88c41c3e3ca81dade548d68a41fc4e4f 877 Gene3D G3DSA:3.30.980.10 565 699 5.7E-51 T 14-10-2018 Tharo_2365 88c41c3e3ca81dade548d68a41fc4e4f 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 205 216 5.6E-32 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Tharo_2365 88c41c3e3ca81dade548d68a41fc4e4f 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 306 319 5.6E-32 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Tharo_2365 88c41c3e3ca81dade548d68a41fc4e4f 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 232 245 5.6E-32 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Tharo_2365 88c41c3e3ca81dade548d68a41fc4e4f 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 282 298 5.6E-32 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Tharo_2365 88c41c3e3ca81dade548d68a41fc4e4f 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 5.6E-32 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Tharo_2365 88c41c3e3ca81dade548d68a41fc4e4f 877 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 877 200.871 T 14-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 Tharo_2365 88c41c3e3ca81dade548d68a41fc4e4f 877 Gene3D G3DSA:3.30.54.20 627 679 5.7E-51 T 14-10-2018 Tharo_2365 88c41c3e3ca81dade548d68a41fc4e4f 877 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 856 0.0 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Tharo_0995 fc1a93960045126d7240a5e1e2c5e2d0 442 PIRSF PIRSF006485 1 440 3.6E-168 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 Tharo_0995 fc1a93960045126d7240a5e1e2c5e2d0 442 Pfam PF01926 50S ribosome-binding GTPase 5 120 2.6E-25 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_0995 fc1a93960045126d7240a5e1e2c5e2d0 442 Pfam PF01926 50S ribosome-binding GTPase 178 296 5.3E-24 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_0995 fc1a93960045126d7240a5e1e2c5e2d0 442 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 8.4E-8 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_0995 fc1a93960045126d7240a5e1e2c5e2d0 442 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 73 91 8.4E-8 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_0995 fc1a93960045126d7240a5e1e2c5e2d0 442 Hamap MF_00195 GTPase Der [der]. 2 435 37.093 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 Tharo_0995 fc1a93960045126d7240a5e1e2c5e2d0 442 Gene3D G3DSA:3.40.50.300 1 161 3.9E-42 T 14-10-2018 Tharo_0995 fc1a93960045126d7240a5e1e2c5e2d0 442 SUPERFAMILY SSF52540 3 165 5.34E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0995 fc1a93960045126d7240a5e1e2c5e2d0 442 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 432 1.0E-167 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 Tharo_0995 fc1a93960045126d7240a5e1e2c5e2d0 442 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 160 3.2E-18 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Tharo_0995 fc1a93960045126d7240a5e1e2c5e2d0 442 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 176 342 5.4E-26 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Tharo_0995 fc1a93960045126d7240a5e1e2c5e2d0 442 Gene3D G3DSA:3.30.300.20 353 434 6.3E-20 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta Tharo_0995 fc1a93960045126d7240a5e1e2c5e2d0 442 SMART SM00382 1 142 5.9 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0995 fc1a93960045126d7240a5e1e2c5e2d0 442 SMART SM00382 175 323 5.3E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0995 fc1a93960045126d7240a5e1e2c5e2d0 442 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 354 432 8.3E-25 T 14-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like Tharo_0995 fc1a93960045126d7240a5e1e2c5e2d0 442 Gene3D G3DSA:3.40.50.300 172 346 1.1E-46 T 14-10-2018 Tharo_0995 fc1a93960045126d7240a5e1e2c5e2d0 442 SUPERFAMILY SSF52540 138 438 5.62E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0659 1b678814fb37af3e2b12ce14c52801e6 426 Gene3D G3DSA:3.30.160.390 8 94 4.0E-25 T 14-10-2018 IPR038488 Integrase, DNA-binding domain superfamily Tharo_0659 1b678814fb37af3e2b12ce14c52801e6 426 Gene3D G3DSA:1.10.150.130 97 209 3.0E-28 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Tharo_0659 1b678814fb37af3e2b12ce14c52801e6 426 Pfam PF13356 Arm DNA-binding domain 9 93 4.3E-18 T 14-10-2018 IPR025166 Integrase, DNA-binding domain Tharo_0659 1b678814fb37af3e2b12ce14c52801e6 426 SUPERFAMILY SSF56349 105 387 3.83E-54 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Tharo_0659 1b678814fb37af3e2b12ce14c52801e6 426 Pfam PF00589 Phage integrase family 215 365 3.9E-17 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Tharo_0659 1b678814fb37af3e2b12ce14c52801e6 426 Gene3D G3DSA:1.10.443.10 212 388 1.7E-14 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Tharo_1905 d9bceeecd3207d5b87375ea6f31af74d 78 Gene3D G3DSA:1.10.10.1130 1 78 3.1E-32 T 14-10-2018 Tharo_1905 d9bceeecd3207d5b87375ea6f31af74d 78 Pfam PF10982 Protein of unknown function (DUF2789) 1 75 1.0E-32 T 14-10-2018 IPR021250 Protein of unknown function DUF2789 Tharo_2111 7f5a227f04f2bea265666c4f2f4c8ced 135 Pfam PF05635 23S rRNA-intervening sequence protein 14 106 2.8E-11 T 14-10-2018 IPR012657 23S rRNA-intervening sequence protein Tharo_2111 7f5a227f04f2bea265666c4f2f4c8ced 135 Gene3D G3DSA:1.20.1440.60 8 131 5.6E-10 T 14-10-2018 IPR036583 23S rRNA-intervening sequence superfamily Tharo_2111 7f5a227f04f2bea265666c4f2f4c8ced 135 TIGRFAM TIGR02436 TIGR02436: four helix bundle protein 15 106 7.4E-6 T 14-10-2018 IPR012657 23S rRNA-intervening sequence protein Tharo_2111 7f5a227f04f2bea265666c4f2f4c8ced 135 SUPERFAMILY SSF158446 12 129 1.83E-13 T 14-10-2018 IPR036583 23S rRNA-intervening sequence superfamily Tharo_2591 8164a66a0c63ec0f47b74de510431b74 503 Pfam PF01565 FAD binding domain 60 198 2.9E-38 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Tharo_2591 8164a66a0c63ec0f47b74de510431b74 503 SUPERFAMILY SSF55103 208 478 7.36E-76 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 Tharo_2591 8164a66a0c63ec0f47b74de510431b74 503 Pfam PF02913 FAD linked oxidases, C-terminal domain 235 474 3.3E-66 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 Tharo_2591 8164a66a0c63ec0f47b74de510431b74 503 Gene3D G3DSA:1.10.45.10 436 476 5.1E-7 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 Tharo_2591 8164a66a0c63ec0f47b74de510431b74 503 Gene3D G3DSA:3.30.465.40 29 255 7.8E-60 T 14-10-2018 Tharo_2591 8164a66a0c63ec0f47b74de510431b74 503 Gene3D G3DSA:3.30.70.2740 354 435 2.4E-9 T 14-10-2018 Tharo_2591 8164a66a0c63ec0f47b74de510431b74 503 SUPERFAMILY SSF56176 25 235 2.2E-66 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Tharo_0557 a27b162ecc5507e720fef0bd5690936e 285 SMART SM01232 130 222 1.4E-45 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 Tharo_0557 a27b162ecc5507e720fef0bd5690936e 285 Pfam PF06827 Zinc finger found in FPG and IleRS 242 270 2.7E-12 T 14-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 Tharo_0557 a27b162ecc5507e720fef0bd5690936e 285 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 113 3.5E-31 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 Tharo_0557 a27b162ecc5507e720fef0bd5690936e 285 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 270 43.195 T 14-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 Tharo_0557 a27b162ecc5507e720fef0bd5690936e 285 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 269 5.3E-84 T 14-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 Tharo_0557 a27b162ecc5507e720fef0bd5690936e 285 SUPERFAMILY SSF46946 131 222 3.83E-28 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 Tharo_0557 a27b162ecc5507e720fef0bd5690936e 285 Gene3D G3DSA:3.20.190.10 2 125 2.9E-34 T 14-10-2018 IPR035937 MutM-like, N-terminal Tharo_0557 a27b162ecc5507e720fef0bd5690936e 285 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 130 219 5.2E-23 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 Tharo_0557 a27b162ecc5507e720fef0bd5690936e 285 SMART SM00898 2 115 1.4E-49 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 Tharo_0557 a27b162ecc5507e720fef0bd5690936e 285 ProSitePatterns PS01242 Zinc finger FPG-type signature. 245 269 - T 14-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 Tharo_0557 a27b162ecc5507e720fef0bd5690936e 285 Gene3D G3DSA:1.10.8.50 140 270 3.0E-45 T 14-10-2018 Tharo_0557 a27b162ecc5507e720fef0bd5690936e 285 SUPERFAMILY SSF81624 2 139 1.7E-39 T 14-10-2018 IPR035937 MutM-like, N-terminal Tharo_0557 a27b162ecc5507e720fef0bd5690936e 285 SUPERFAMILY SSF57716 218 270 1.03E-17 T 14-10-2018 Tharo_1399 0c0b853cf85bf7b1c2407212e315034a 362 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 295 324 - T 14-10-2018 IPR030390 RNA methyltransferase TrmA, active site Tharo_1399 0c0b853cf85bf7b1c2407212e315034a 362 Gene3D G3DSA:3.40.1350.30 45 185 8.1E-119 T 14-10-2018 Tharo_1399 0c0b853cf85bf7b1c2407212e315034a 362 TIGRFAM TIGR02143 trmA_only: tRNA (uracil(54)-C(5))-methyltransferase 11 362 8.7E-147 T 14-10-2018 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 Tharo_1399 0c0b853cf85bf7b1c2407212e315034a 362 SUPERFAMILY SSF53335 10 361 4.55E-45 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_1399 0c0b853cf85bf7b1c2407212e315034a 362 Gene3D G3DSA:3.40.50.150 13 357 8.1E-119 T 14-10-2018 Tharo_1399 0c0b853cf85bf7b1c2407212e315034a 362 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 11 362 6.7E-143 T 14-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 Tharo_1399 0c0b853cf85bf7b1c2407212e315034a 362 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 344 354 - T 14-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site Tharo_1399 0c0b853cf85bf7b1c2407212e315034a 362 Hamap MF_01011 tRNA/tmRNA (uracil-C(5))-methyltransferase [trmA]. 4 362 40.126 T 14-10-2018 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 Tharo_2822 9cc9db64ca2ff150616202f2960802e5 231 Pfam PF13462 Thioredoxin 53 197 4.0E-34 T 14-10-2018 IPR012336 Thioredoxin-like fold Tharo_2822 9cc9db64ca2ff150616202f2960802e5 231 SUPERFAMILY SSF52833 42 223 1.12E-42 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_2822 9cc9db64ca2ff150616202f2960802e5 231 Gene3D G3DSA:3.40.30.10 52 223 2.2E-52 T 14-10-2018 Tharo_2822 9cc9db64ca2ff150616202f2960802e5 231 Gene3D G3DSA:1.10.40.80 108 168 2.2E-52 T 14-10-2018 Tharo_2383 c1ca30de855482941f30a2a75d22ce2a 170 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 82.813 T 14-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 Tharo_2383 c1ca30de855482941f30a2a75d22ce2a 170 Pfam PF03477 ATP cone domain 50 136 1.6E-15 T 14-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 Tharo_2383 c1ca30de855482941f30a2a75d22ce2a 170 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 146 7.6E-56 T 14-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 Tharo_0129 97ef718153cc1e7ef7042899f9b215dd 441 Gene3D G3DSA:3.90.220.20 18 427 1.7E-68 T 14-10-2018 Tharo_0129 97ef718153cc1e7ef7042899f9b215dd 441 SUPERFAMILY SSF116734 209 431 1.08E-44 T 14-10-2018 Tharo_0129 97ef718153cc1e7ef7042899f9b215dd 441 Gene3D G3DSA:1.10.287.1120 157 423 1.7E-68 T 14-10-2018 Tharo_0129 97ef718153cc1e7ef7042899f9b215dd 441 SUPERFAMILY SSF116734 6 210 1.41E-34 T 14-10-2018 Tharo_0129 97ef718153cc1e7ef7042899f9b215dd 441 Pfam PF01420 Type I restriction modification DNA specificity domain 280 400 9.9E-8 T 14-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 Tharo_0129 97ef718153cc1e7ef7042899f9b215dd 441 Gene3D G3DSA:3.90.220.20 229 376 1.7E-68 T 14-10-2018 Tharo_1761 2a654bc5534d3c88cd2fc3b96a055992 208 SUPERFAMILY SSF81452 17 207 6.15E-48 T 14-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_1761 2a654bc5534d3c88cd2fc3b96a055992 208 Gene3D G3DSA:1.20.120.80 27 208 5.4E-48 T 14-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_1761 2a654bc5534d3c88cd2fc3b96a055992 208 Pfam PF00510 Cytochrome c oxidase subunit III 31 206 4.1E-14 T 14-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_3301 fded4c8faa73e158fc059e3aa80b41f9 214 Gene3D G3DSA:3.60.15.10 2 210 2.8E-81 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_3301 fded4c8faa73e158fc059e3aa80b41f9 214 SMART SM00849 13 193 1.4E-38 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_3301 fded4c8faa73e158fc059e3aa80b41f9 214 Pfam PF00753 Metallo-beta-lactamase superfamily 11 193 4.3E-32 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_3301 fded4c8faa73e158fc059e3aa80b41f9 214 SUPERFAMILY SSF56281 3 209 4.47E-60 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_1507 04b0f657413454848c2686cbf1cdb3ce 120 Pfam PF07238 PilZ domain 15 103 5.5E-8 T 14-10-2018 IPR009875 PilZ domain GO:0035438 Tharo_1507 04b0f657413454848c2686cbf1cdb3ce 120 Gene3D G3DSA:2.40.10.220 6 120 8.9E-44 T 14-10-2018 Tharo_1547 0a0ea885a562e951e97ada00f030a4d3 106 Gene3D G3DSA:3.30.300.130 3 105 2.8E-32 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Tharo_1547 0a0ea885a562e951e97ada00f030a4d3 106 SUPERFAMILY SSF117916 8 103 8.5E-27 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Tharo_1547 0a0ea885a562e951e97ada00f030a4d3 106 Pfam PF01883 Iron-sulfur cluster assembly protein 10 73 2.7E-20 T 14-10-2018 IPR002744 MIP18 family-like Tharo_3208 9c442e754b3ae99364bdb7409aaf4094 274 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 8 214 7.3E-43 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Tharo_3208 9c442e754b3ae99364bdb7409aaf4094 274 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 8 258 6.8E-95 T 14-10-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 Tharo_3208 9c442e754b3ae99364bdb7409aaf4094 274 Gene3D G3DSA:3.30.950.10 116 236 2.2E-41 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 Tharo_3208 9c442e754b3ae99364bdb7409aaf4094 274 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 81 114 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Tharo_3208 9c442e754b3ae99364bdb7409aaf4094 274 Gene3D G3DSA:3.40.1010.10 3 115 1.7E-27 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Tharo_3208 9c442e754b3ae99364bdb7409aaf4094 274 SUPERFAMILY SSF53790 4 258 5.1E-62 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Tharo_3208 9c442e754b3ae99364bdb7409aaf4094 274 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 11 25 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Tharo_1545 75ba32e08fad94fc47d845ce4a5f3b43 203 SUPERFAMILY SSF55729 20 160 3.32E-18 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Tharo_1545 75ba32e08fad94fc47d845ce4a5f3b43 203 Gene3D G3DSA:3.40.630.30 2 162 7.6E-40 T 14-10-2018 Tharo_2878 1873c0ee503c6cfc031fec519ff2c711 425 Pfam PF07676 WD40-like Beta Propeller Repeat 325 351 0.072 T 14-10-2018 IPR011659 WD40-like Beta Propeller Tharo_2878 1873c0ee503c6cfc031fec519ff2c711 425 Pfam PF07676 WD40-like Beta Propeller Repeat 366 391 0.0026 T 14-10-2018 IPR011659 WD40-like Beta Propeller Tharo_2878 1873c0ee503c6cfc031fec519ff2c711 425 Pfam PF07676 WD40-like Beta Propeller Repeat 195 223 6.3E-7 T 14-10-2018 IPR011659 WD40-like Beta Propeller Tharo_2878 1873c0ee503c6cfc031fec519ff2c711 425 Pfam PF07676 WD40-like Beta Propeller Repeat 235 266 1.1E-6 T 14-10-2018 IPR011659 WD40-like Beta Propeller Tharo_2878 1873c0ee503c6cfc031fec519ff2c711 425 Pfam PF07676 WD40-like Beta Propeller Repeat 276 310 5.7E-8 T 14-10-2018 IPR011659 WD40-like Beta Propeller Tharo_2878 1873c0ee503c6cfc031fec519ff2c711 425 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 22 421 9.7E-150 T 14-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 Tharo_2878 1873c0ee503c6cfc031fec519ff2c711 425 Hamap MF_00671 Tol-Pal system protein TolB [tolB]. 8 420 45.898 T 14-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 Tharo_2878 1873c0ee503c6cfc031fec519ff2c711 425 SUPERFAMILY SSF69304 152 422 9.15E-56 T 14-10-2018 Tharo_2878 1873c0ee503c6cfc031fec519ff2c711 425 Pfam PF04052 TolB amino-terminal domain 27 125 2.1E-22 T 14-10-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 Tharo_2878 1873c0ee503c6cfc031fec519ff2c711 425 SUPERFAMILY SSF52964 32 159 1.31E-29 T 14-10-2018 Tharo_2878 1873c0ee503c6cfc031fec519ff2c711 425 Gene3D G3DSA:2.120.10.30 163 425 4.7E-86 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Tharo_2878 1873c0ee503c6cfc031fec519ff2c711 425 Gene3D G3DSA:3.40.50.10070 23 162 5.2E-30 T 14-10-2018 IPR036752 TolB, N-terminal domain superfamily GO:0015031|GO:0042597 Tharo_0522 c61bdab1fd44d14287b6bb524aea8b60 278 Gene3D G3DSA:2.30.30.100 224 272 2.5E-13 T 14-10-2018 Tharo_0522 c61bdab1fd44d14287b6bb524aea8b60 278 SUPERFAMILY SSF50037 225 270 2.11E-8 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal Tharo_0522 c61bdab1fd44d14287b6bb524aea8b60 278 Gene3D G3DSA:3.30.930.10 15 223 6.9E-52 T 14-10-2018 Tharo_0522 c61bdab1fd44d14287b6bb524aea8b60 278 Pfam PF02237 Biotin protein ligase C terminal domain 234 270 3.6E-5 T 14-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Tharo_0522 c61bdab1fd44d14287b6bb524aea8b60 278 Pfam PF03099 Biotin/lipoate A/B protein ligase family 53 155 8.0E-13 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 Tharo_0522 c61bdab1fd44d14287b6bb524aea8b60 278 SUPERFAMILY SSF55681 20 221 9.82E-48 T 14-10-2018 Tharo_0522 c61bdab1fd44d14287b6bb524aea8b60 278 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 26 270 1.7E-48 T 14-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Tharo_2881 b87cfb4d60a2c267b5e9ba70c93dfdf0 223 TIGRFAM TIGR04349 rSAM_QueE_gams: putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 14 223 4.5E-108 T 14-10-2018 IPR027621 Putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE Tharo_2881 b87cfb4d60a2c267b5e9ba70c93dfdf0 223 PIRSF PIRSF000370 12 223 4.7E-69 T 14-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 Tharo_2881 b87cfb4d60a2c267b5e9ba70c93dfdf0 223 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 14 220 38.775 T 14-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 Tharo_2881 b87cfb4d60a2c267b5e9ba70c93dfdf0 223 SUPERFAMILY SSF102114 35 114 4.71E-14 T 14-10-2018 Tharo_2881 b87cfb4d60a2c267b5e9ba70c93dfdf0 223 Pfam PF04055 Radical SAM superfamily 37 128 3.1E-14 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_2881 b87cfb4d60a2c267b5e9ba70c93dfdf0 223 Gene3D G3DSA:3.20.20.70 14 217 2.2E-36 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_2881 b87cfb4d60a2c267b5e9ba70c93dfdf0 223 Pfam PF13394 4Fe-4S single cluster domain 35 116 1.1E-9 T 14-10-2018 Tharo_1102 71befcbfa3603ef2e39739a8017899f7 148 Pfam PF07746 Aromatic-ring-opening dioxygenase LigAB, LigA subunit 27 112 7.6E-38 T 14-10-2018 IPR011986 Extradiol ring-cleavage dioxygenase LigAB, LigA subunit Tharo_1102 71befcbfa3603ef2e39739a8017899f7 148 TIGRFAM TIGR02792 PCA_ligA: protocatechuate 4,5-dioxygenase, alpha subunit 7 123 2.4E-72 T 14-10-2018 IPR014159 Protocatechuate 4,5-dioxygenase, alpha subunit KEGG: 00362+1.13.11.8|KEGG: 00624+1.13.11.8|KEGG: 00627+1.13.11.8|MetaCyc: PWY-6216|MetaCyc: PWY-6217 Tharo_1102 71befcbfa3603ef2e39739a8017899f7 148 Gene3D G3DSA:1.10.700.10 2 128 1.3E-59 T 14-10-2018 IPR036622 Dioxygenase LigAB, LigA subunit superfamily Tharo_1102 71befcbfa3603ef2e39739a8017899f7 148 SUPERFAMILY SSF48076 4 127 3.53E-53 T 14-10-2018 IPR036622 Dioxygenase LigAB, LigA subunit superfamily Tharo_0101 1014f4bdd9c81fbabd7c66fa5d1c9a77 398 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 396 1.3E-24 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Tharo_0101 1014f4bdd9c81fbabd7c66fa5d1c9a77 398 SUPERFAMILY SSF56645 2 244 3.4E-76 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Tharo_0101 1014f4bdd9c81fbabd7c66fa5d1c9a77 398 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 212 3.1E-20 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Tharo_0101 1014f4bdd9c81fbabd7c66fa5d1c9a77 398 Gene3D G3DSA:1.10.540.10 2 120 3.4E-29 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Tharo_0101 1014f4bdd9c81fbabd7c66fa5d1c9a77 398 Gene3D G3DSA:1.20.140.10 235 398 5.6E-38 T 14-10-2018 Tharo_0101 1014f4bdd9c81fbabd7c66fa5d1c9a77 398 Gene3D G3DSA:2.40.110.10 125 234 1.2E-36 T 14-10-2018 Tharo_0101 1014f4bdd9c81fbabd7c66fa5d1c9a77 398 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 121 3.4E-20 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Tharo_0101 1014f4bdd9c81fbabd7c66fa5d1c9a77 398 SUPERFAMILY SSF47203 231 398 2.26E-24 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Tharo_1900 65d3bf72087eb106234191730e0e54b9 332 Gene3D G3DSA:3.40.190.10 108 254 1.1E-90 T 14-10-2018 Tharo_1900 65d3bf72087eb106234191730e0e54b9 332 Gene3D G3DSA:3.40.190.10 28 290 1.1E-90 T 14-10-2018 Tharo_1900 65d3bf72087eb106234191730e0e54b9 332 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 8 292 2.5E-88 T 14-10-2018 IPR011862 Phosphate binding protein GO:0042301 Tharo_1900 65d3bf72087eb106234191730e0e54b9 332 SUPERFAMILY SSF53850 28 305 4.59E-73 T 14-10-2018 Tharo_1900 65d3bf72087eb106234191730e0e54b9 332 Pfam PF12727 PBP superfamily domain 44 276 2.9E-36 T 14-10-2018 IPR024370 PBP domain Tharo_1419 0da80dd7fb0aecd211f650b368237d98 486 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 82 3.8E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_1419 0da80dd7fb0aecd211f650b368237d98 486 Gene3D G3DSA:3.40.640.10 158 376 1.7E-97 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_1419 0da80dd7fb0aecd211f650b368237d98 486 Pfam PF00155 Aminotransferase class I and II 164 469 4.1E-28 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Tharo_1419 0da80dd7fb0aecd211f650b368237d98 486 Gene3D G3DSA:3.90.1150.10 113 482 1.7E-97 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_1419 0da80dd7fb0aecd211f650b368237d98 486 SUPERFAMILY SSF53383 110 484 1.26E-89 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_1419 0da80dd7fb0aecd211f650b368237d98 486 SUPERFAMILY SSF46785 15 85 1.17E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1419 0da80dd7fb0aecd211f650b368237d98 486 SMART SM00345 23 82 4.4E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_1419 0da80dd7fb0aecd211f650b368237d98 486 Gene3D G3DSA:1.10.10.10 13 83 1.1E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2621 c04b377e1b3895d2db2ac6564b9a0e6d 388 SUPERFAMILY SSF56059 103 301 3.54E-55 T 14-10-2018 Tharo_2621 c04b377e1b3895d2db2ac6564b9a0e6d 388 SUPERFAMILY SSF52440 7 101 1.38E-25 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Tharo_2621 c04b377e1b3895d2db2ac6564b9a0e6d 388 Gene3D G3DSA:3.40.50.20 1 112 1.3E-37 T 14-10-2018 Tharo_2621 c04b377e1b3895d2db2ac6564b9a0e6d 388 Gene3D G3DSA:3.30.470.20 181 385 1.3E-71 T 14-10-2018 Tharo_2621 c04b377e1b3895d2db2ac6564b9a0e6d 388 Pfam PF02222 ATP-grasp domain 112 283 2.7E-44 T 14-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type Tharo_2621 c04b377e1b3895d2db2ac6564b9a0e6d 388 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 7 369 39.27 T 14-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 Tharo_2621 c04b377e1b3895d2db2ac6564b9a0e6d 388 Gene3D G3DSA:3.30.1490.20 113 180 8.6E-20 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Tharo_2621 c04b377e1b3895d2db2ac6564b9a0e6d 388 SUPERFAMILY SSF51246 307 377 3.45E-16 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 Tharo_2621 c04b377e1b3895d2db2ac6564b9a0e6d 388 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 7 373 8.1E-109 T 14-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 Tharo_0072 3f983f7cf336ab4d49efa67d2ed709e6 172 Pfam PF01899 Na+/H+ ion antiporter subunit 12 161 2.0E-36 T 14-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 Tharo_0072 3f983f7cf336ab4d49efa67d2ed709e6 172 PIRSF PIRSF019239 1 166 5.1E-35 T 14-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 Tharo_2406 cf664ede4e5641723b7bc9f4b2e1ad00 90 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 5.4E-44 T 14-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 Tharo_2406 cf664ede4e5641723b7bc9f4b2e1ad00 90 Gene3D G3DSA:1.10.3880.10 1 90 1.4E-40 T 14-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 Tharo_2406 cf664ede4e5641723b7bc9f4b2e1ad00 90 SUPERFAMILY SSF111148 1 89 2.09E-40 T 14-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 Tharo_2406 cf664ede4e5641723b7bc9f4b2e1ad00 90 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 75 4.0E-31 T 14-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 Tharo_2406 cf664ede4e5641723b7bc9f4b2e1ad00 90 PIRSF PIRSF029827 1 90 2.5E-40 T 14-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 Tharo_2406 cf664ede4e5641723b7bc9f4b2e1ad00 90 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 28.566 T 14-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 Tharo_0733 803b93ff1751fb38c818cc14173d7329 673 SMART SM00493 1 122 5.8E-19 T 14-10-2018 IPR006171 TOPRIM domain Tharo_0733 803b93ff1751fb38c818cc14173d7329 673 SUPERFAMILY SSF56712 1 602 7.59E-176 T 14-10-2018 IPR023405 DNA topoisomerase, type IA, core domain Tharo_0733 803b93ff1751fb38c818cc14173d7329 673 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 648 2.0E-218 T 14-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 Tharo_0733 803b93ff1751fb38c818cc14173d7329 673 SMART SM00436 122 217 8.5E-33 T 14-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 Tharo_0733 803b93ff1751fb38c818cc14173d7329 673 Gene3D G3DSA:3.30.65.10 607 656 1.9E-5 T 14-10-2018 Tharo_0733 803b93ff1751fb38c818cc14173d7329 673 Pfam PF01751 Toprim domain 3 128 2.5E-15 T 14-10-2018 IPR006171 TOPRIM domain Tharo_0733 803b93ff1751fb38c818cc14173d7329 673 SUPERFAMILY SSF57783 616 650 9.52E-10 T 14-10-2018 Tharo_0733 803b93ff1751fb38c818cc14173d7329 673 Pfam PF01131 DNA topoisomerase 152 586 1.2E-110 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Tharo_0733 803b93ff1751fb38c818cc14173d7329 673 Gene3D G3DSA:1.10.290.10 280 409 4.0E-148 T 14-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 Tharo_0733 803b93ff1751fb38c818cc14173d7329 673 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 308 323 - T 14-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 Tharo_0733 803b93ff1751fb38c818cc14173d7329 673 Gene3D G3DSA:3.40.50.140 1 149 2.4E-49 T 14-10-2018 Tharo_0733 803b93ff1751fb38c818cc14173d7329 673 SMART SM00437 271 555 2.6E-66 T 14-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 Tharo_0733 803b93ff1751fb38c818cc14173d7329 673 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 617 651 4.8E-10 T 14-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 Tharo_0733 803b93ff1751fb38c818cc14173d7329 673 Gene3D G3DSA:2.70.20.10 211 485 4.0E-148 T 14-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 Tharo_0733 803b93ff1751fb38c818cc14173d7329 673 Gene3D G3DSA:1.10.460.10 156 599 4.0E-148 T 14-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 Tharo_0733 803b93ff1751fb38c818cc14173d7329 673 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 518 532 5.5E-25 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Tharo_0733 803b93ff1751fb38c818cc14173d7329 673 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 395 411 5.5E-25 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Tharo_0733 803b93ff1751fb38c818cc14173d7329 673 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 314 323 5.5E-25 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Tharo_0733 803b93ff1751fb38c818cc14173d7329 673 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 96 109 5.5E-25 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Tharo_0733 803b93ff1751fb38c818cc14173d7329 673 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 187 205 5.5E-25 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Tharo_2319 1ff1590e959878c2834bef47ebe6a573 77 Gene3D G3DSA:3.30.1390.10 1 77 1.5E-36 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like Tharo_2319 1ff1590e959878c2834bef47ebe6a573 77 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 1 72 23.197 T 14-10-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS Tharo_2319 1ff1590e959878c2834bef47ebe6a573 77 SUPERFAMILY SSF54736 1 76 8.89E-30 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like Tharo_2319 1ff1590e959878c2834bef47ebe6a573 77 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 1 72 1.4E-31 T 14-10-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 Tharo_1010 450a22c8a65a92d3b23374ba70dff574 404 Pfam PF07690 Major Facilitator Superfamily 24 350 3.1E-43 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_1010 450a22c8a65a92d3b23374ba70dff574 404 SUPERFAMILY SSF103473 4 389 2.62E-60 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_1010 450a22c8a65a92d3b23374ba70dff574 404 Gene3D G3DSA:1.20.1250.20 9 392 9.8E-88 T 14-10-2018 Tharo_3158 48f30ab73ffac8b96f2c6be1030ae7bd 278 Gene3D G3DSA:1.20.1080.10 4 268 1.8E-62 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 Tharo_3158 48f30ab73ffac8b96f2c6be1030ae7bd 278 Pfam PF01226 Formate/nitrite transporter 10 258 6.2E-62 T 14-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 Tharo_2289 5cae4d4a131a42d4f3c71dfa8f96d8c0 227 Pfam PF00027 Cyclic nucleotide-binding domain 36 124 1.2E-19 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Tharo_2289 5cae4d4a131a42d4f3c71dfa8f96d8c0 227 SUPERFAMILY SSF51206 12 150 5.37E-33 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like Tharo_2289 5cae4d4a131a42d4f3c71dfa8f96d8c0 227 Gene3D G3DSA:2.60.120.10 8 150 8.6E-40 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Tharo_2289 5cae4d4a131a42d4f3c71dfa8f96d8c0 227 Gene3D G3DSA:1.10.10.10 151 226 2.3E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2289 5cae4d4a131a42d4f3c71dfa8f96d8c0 227 SMART SM00100 18 136 8.5E-16 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Tharo_2289 5cae4d4a131a42d4f3c71dfa8f96d8c0 227 SUPERFAMILY SSF46785 155 225 1.88E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_2289 5cae4d4a131a42d4f3c71dfa8f96d8c0 227 Pfam PF13545 Crp-like helix-turn-helix domain 156 225 8.4E-18 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Tharo_2289 5cae4d4a131a42d4f3c71dfa8f96d8c0 227 SMART SM00419 170 218 3.9E-12 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Tharo_2490 9927c6eb213ec3bddab9f638c63c2488 367 Pfam PF01594 AI-2E family transporter 19 337 6.4E-58 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like Tharo_2106 7fb52f341a12c955d95975d17235c1c9 132 SUPERFAMILY SSF53955 2 132 1.69E-46 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily Tharo_2106 7fb52f341a12c955d95975d17235c1c9 132 Pfam PF00959 Phage lysozyme 16 122 1.8E-14 T 14-10-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 Tharo_2106 7fb52f341a12c955d95975d17235c1c9 132 Gene3D G3DSA:1.10.530.40 1 131 8.1E-49 T 14-10-2018 Tharo_2496 2c2e0fb2b2d20be5d5249f3e90ac66b6 271 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 16 271 4.5E-96 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 Tharo_2496 2c2e0fb2b2d20be5d5249f3e90ac66b6 271 Gene3D G3DSA:3.20.20.60 8 271 9.1E-109 T 14-10-2018 Tharo_2496 2c2e0fb2b2d20be5d5249f3e90ac66b6 271 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 10 271 42.853 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 Tharo_2496 2c2e0fb2b2d20be5d5249f3e90ac66b6 271 Pfam PF02548 Ketopantoate hydroxymethyltransferase 10 266 1.8E-110 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 Tharo_2496 2c2e0fb2b2d20be5d5249f3e90ac66b6 271 SUPERFAMILY SSF51621 10 271 1.81E-102 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Tharo_2496 2c2e0fb2b2d20be5d5249f3e90ac66b6 271 PIRSF PIRSF000388 1 271 2.8E-104 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 Tharo_1978 cd4d06ed36bba13844e1f32916e78488 312 SMART SM00986 152 299 2.1E-43 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Tharo_1978 cd4d06ed36bba13844e1f32916e78488 312 Gene3D G3DSA:3.40.470.10 127 311 1.4E-74 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Tharo_1978 cd4d06ed36bba13844e1f32916e78488 312 SUPERFAMILY SSF52141 128 307 8.18E-65 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Tharo_1978 cd4d06ed36bba13844e1f32916e78488 312 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 138 299 3.0E-60 T 14-10-2018 IPR005273 Uracil-DNA glycosylase family 4 Tharo_1978 cd4d06ed36bba13844e1f32916e78488 312 SMART SM00987 152 299 2.1E-43 T 14-10-2018 Tharo_1978 cd4d06ed36bba13844e1f32916e78488 312 Pfam PF03167 Uracil DNA glycosylase superfamily 152 298 4.6E-48 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Tharo_2014 d079f1a738170b4a6beeb09158d9085b 280 SMART SM00382 28 224 5.2E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2014 d079f1a738170b4a6beeb09158d9085b 280 Gene3D G3DSA:3.40.50.300 5 274 7.5E-46 T 14-10-2018 Tharo_2014 d079f1a738170b4a6beeb09158d9085b 280 SUPERFAMILY SSF52540 4 237 1.81E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2014 d079f1a738170b4a6beeb09158d9085b 280 Pfam PF00005 ABC transporter 19 174 6.7E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_2014 d079f1a738170b4a6beeb09158d9085b 280 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_2164 f343be1945c55a7fe1e951ca34510473 242 Pfam PF00929 Exonuclease 4 165 1.1E-35 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Tharo_2164 f343be1945c55a7fe1e951ca34510473 242 Gene3D G3DSA:3.30.420.10 1 179 9.8E-55 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_2164 f343be1945c55a7fe1e951ca34510473 242 SMART SM00479 2 174 1.3E-52 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Tharo_2164 f343be1945c55a7fe1e951ca34510473 242 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 4 180 3.8E-59 T 14-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_2164 f343be1945c55a7fe1e951ca34510473 242 SUPERFAMILY SSF53098 1 175 3.36E-55 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_2164 f343be1945c55a7fe1e951ca34510473 242 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 2 231 3.5E-89 T 14-10-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_2432 5a1271c70fb37867b3d454f3d6843925 354 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 85 - T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Tharo_2432 5a1271c70fb37867b3d454f3d6843925 354 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 139 150 - T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Tharo_2432 5a1271c70fb37867b3d454f3d6843925 354 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 327 4.4E-95 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Tharo_2432 5a1271c70fb37867b3d454f3d6843925 354 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 328 8.7E-100 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Tharo_2432 5a1271c70fb37867b3d454f3d6843925 354 TIGRFAM TIGR01521 FruBisAldo_II_B: fructose-bisphosphate aldolase, class II, Calvin cycle subtype 3 349 3.9E-191 T 14-10-2018 IPR006412 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 Tharo_2432 5a1271c70fb37867b3d454f3d6843925 354 SUPERFAMILY SSF51569 3 328 2.49E-109 T 14-10-2018 Tharo_2432 5a1271c70fb37867b3d454f3d6843925 354 PIRSF PIRSF001359 1 329 2.7E-85 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Tharo_2432 5a1271c70fb37867b3d454f3d6843925 354 Gene3D G3DSA:3.20.20.70 1 354 2.2E-152 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_1266 7f5cc610f85d49e75171e6838b381458 157 SUPERFAMILY SSF46955 22 128 6.23E-26 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily Tharo_1266 7f5cc610f85d49e75171e6838b381458 157 Pfam PF09278 MerR, DNA binding 63 127 3.0E-15 T 14-10-2018 IPR015358 Transcription regulator MerR, DNA binding Tharo_1266 7f5cc610f85d49e75171e6838b381458 157 Gene3D G3DSA:1.10.1660.10 9 131 9.0E-27 T 14-10-2018 Tharo_1266 7f5cc610f85d49e75171e6838b381458 157 Pfam PF00376 MerR family regulatory protein 23 58 4.5E-10 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Tharo_1266 7f5cc610f85d49e75171e6838b381458 157 SMART SM00422 22 89 1.5E-19 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Tharo_3141 98fa6f32cc0fc4bfd82420edac77d75e 325 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 314 1.2E-136 T 14-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 Tharo_3141 98fa6f32cc0fc4bfd82420edac77d75e 325 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 303 4.4E-66 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Tharo_3141 98fa6f32cc0fc4bfd82420edac77d75e 325 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 314 8.1E-132 T 14-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 Tharo_3141 98fa6f32cc0fc4bfd82420edac77d75e 325 Gene3D G3DSA:3.40.50.1100 46 148 8.8E-124 T 14-10-2018 Tharo_3141 98fa6f32cc0fc4bfd82420edac77d75e 325 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 34 52 - T 14-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 Tharo_3141 98fa6f32cc0fc4bfd82420edac77d75e 325 Gene3D G3DSA:3.40.50.1100 12 309 8.8E-124 T 14-10-2018 Tharo_3141 98fa6f32cc0fc4bfd82420edac77d75e 325 SUPERFAMILY SSF53686 4 314 1.31E-97 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Tharo_0372 e1a14a153b704954ce671b66b0939e47 541 Pfam PF13817 IS66 C-terminal element 484 520 1.6E-12 T 14-10-2018 IPR039552 Transposase IS66, C-terminal Tharo_0372 e1a14a153b704954ce671b66b0939e47 541 Pfam PF13007 Transposase C of IS166 homeodomain 48 101 1.5E-8 T 14-10-2018 IPR024463 Transposase TnpC, homeodomain Tharo_0372 e1a14a153b704954ce671b66b0939e47 541 Pfam PF03050 Transposase IS66 family 190 477 8.0E-79 T 14-10-2018 IPR004291 Transposase, IS66 Tharo_0386 824b3efea09685760b00a9947e97d86f 139 Pfam PF01850 PIN domain 6 121 1.7E-7 T 14-10-2018 IPR002716 PIN domain Tharo_0386 824b3efea09685760b00a9947e97d86f 139 Gene3D G3DSA:3.40.50.1010 5 135 8.6E-18 T 14-10-2018 Tharo_0386 824b3efea09685760b00a9947e97d86f 139 SUPERFAMILY SSF88723 1 125 1.21E-16 T 14-10-2018 IPR029060 PIN-like domain superfamily Tharo_2314 39aef263164ea3f078f621783c3d6bae 398 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 5 388 7.1E-129 T 14-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 Tharo_2314 39aef263164ea3f078f621783c3d6bae 398 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 186 364 1.5E-64 T 14-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 Tharo_2314 39aef263164ea3f078f621783c3d6bae 398 SUPERFAMILY SSF102645 184 393 6.28E-70 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 Tharo_2314 39aef263164ea3f078f621783c3d6bae 398 Pfam PF02441 Flavoprotein 8 177 2.5E-41 T 14-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 Tharo_2314 39aef263164ea3f078f621783c3d6bae 398 SUPERFAMILY SSF52507 1 178 4.71E-62 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 Tharo_2314 39aef263164ea3f078f621783c3d6bae 398 Gene3D G3DSA:3.40.50.10300 184 397 9.7E-70 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 Tharo_2314 39aef263164ea3f078f621783c3d6bae 398 Gene3D G3DSA:3.40.50.1950 1 183 2.7E-58 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 Tharo_1980 10a654e81a41c1e41f7c014070290d35 306 SUPERFAMILY SSF46785 4 111 7.71E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1980 10a654e81a41c1e41f7c014070290d35 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 3.5E-23 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1980 10a654e81a41c1e41f7c014070290d35 306 Pfam PF03466 LysR substrate binding domain 87 293 2.5E-48 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_1980 10a654e81a41c1e41f7c014070290d35 306 SUPERFAMILY SSF53850 86 296 5.0E-47 T 14-10-2018 Tharo_1980 10a654e81a41c1e41f7c014070290d35 306 Gene3D G3DSA:3.40.190.290 91 304 9.8E-44 T 14-10-2018 Tharo_1980 10a654e81a41c1e41f7c014070290d35 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.5E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1980 10a654e81a41c1e41f7c014070290d35 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.5E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1980 10a654e81a41c1e41f7c014070290d35 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.5E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Tharo_1980 10a654e81a41c1e41f7c014070290d35 306 Gene3D G3DSA:1.10.10.10 3 86 9.0E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_3256 fbb4f77d9021d9396fa7e827d7f3420b 414 SUPERFAMILY SSF55874 272 407 1.83E-24 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_3256 fbb4f77d9021d9396fa7e827d7f3420b 414 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 310 405 2.5E-11 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_3256 fbb4f77d9021d9396fa7e827d7f3420b 414 Gene3D G3DSA:3.30.565.10 271 408 2.7E-22 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_3256 fbb4f77d9021d9396fa7e827d7f3420b 414 Pfam PF00512 His Kinase A (phospho-acceptor) domain 206 267 8.8E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_3256 fbb4f77d9021d9396fa7e827d7f3420b 414 SMART SM00388 204 270 3.6E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_3256 fbb4f77d9021d9396fa7e827d7f3420b 414 Gene3D G3DSA:1.10.287.130 155 270 1.9E-13 T 14-10-2018 Tharo_3256 fbb4f77d9021d9396fa7e827d7f3420b 414 SMART SM00387 309 411 1.2E-15 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_3256 fbb4f77d9021d9396fa7e827d7f3420b 414 SUPERFAMILY SSF47384 188 267 1.26E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_2206 c601ee0b986d86462fdb77ac5e1d08a0 234 PIRSF PIRSF006102 4 218 9.1E-69 T 14-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 Tharo_2206 c601ee0b986d86462fdb77ac5e1d08a0 234 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 10 207 3.5E-74 T 14-10-2018 IPR010968 Ion-translocating oxidoreductase complex subunit E GO:0016020|GO:0022900 Tharo_2206 c601ee0b986d86462fdb77ac5e1d08a0 234 Hamap MF_00478 Ion-translocating oxidoreductase complex subunit E [rsxE]. 1 210 25.328 T 14-10-2018 IPR010968 Ion-translocating oxidoreductase complex subunit E GO:0016020|GO:0022900 Tharo_2206 c601ee0b986d86462fdb77ac5e1d08a0 234 Pfam PF02508 Rnf-Nqr subunit, membrane protein 9 200 1.5E-59 T 14-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 Tharo_0838 beb3302253fb6ca9e35ad68b13c9d6f8 397 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 205 222 - T 14-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0838 beb3302253fb6ca9e35ad68b13c9d6f8 397 TIGRFAM TIGR00016 ackA: acetate kinase 2 391 1.7E-109 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0838 beb3302253fb6ca9e35ad68b13c9d6f8 397 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 14-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0838 beb3302253fb6ca9e35ad68b13c9d6f8 397 PIRSF PIRSF000722 1 396 2.8E-137 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0838 beb3302253fb6ca9e35ad68b13c9d6f8 397 Hamap MF_00020 Acetate kinase [ackA]. 1 397 160.953 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0838 beb3302253fb6ca9e35ad68b13c9d6f8 397 Gene3D G3DSA:3.30.420.40 200 396 1.1E-70 T 14-10-2018 Tharo_0838 beb3302253fb6ca9e35ad68b13c9d6f8 397 PRINTS PR00471 Acetate kinase family signature 321 337 1.7E-39 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0838 beb3302253fb6ca9e35ad68b13c9d6f8 397 PRINTS PR00471 Acetate kinase family signature 4 15 1.7E-39 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0838 beb3302253fb6ca9e35ad68b13c9d6f8 397 PRINTS PR00471 Acetate kinase family signature 205 226 1.7E-39 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0838 beb3302253fb6ca9e35ad68b13c9d6f8 397 PRINTS PR00471 Acetate kinase family signature 176 189 1.7E-39 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0838 beb3302253fb6ca9e35ad68b13c9d6f8 397 PRINTS PR00471 Acetate kinase family signature 299 312 1.7E-39 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0838 beb3302253fb6ca9e35ad68b13c9d6f8 397 PRINTS PR00471 Acetate kinase family signature 376 388 1.7E-39 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0838 beb3302253fb6ca9e35ad68b13c9d6f8 397 Gene3D G3DSA:3.30.420.40 1 197 1.9E-60 T 14-10-2018 Tharo_0838 beb3302253fb6ca9e35ad68b13c9d6f8 397 Pfam PF00871 Acetokinase family 4 389 8.2E-109 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Tharo_0838 beb3302253fb6ca9e35ad68b13c9d6f8 397 SUPERFAMILY SSF53067 162 394 7.23E-76 T 14-10-2018 Tharo_0838 beb3302253fb6ca9e35ad68b13c9d6f8 397 SUPERFAMILY SSF53067 1 198 1.04E-58 T 14-10-2018 Tharo_1994 73065aa8a0dddf4278b189cc74100678 247 SUPERFAMILY SSF46894 149 237 8.5E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_1994 73065aa8a0dddf4278b189cc74100678 247 SMART SM00448 24 135 4.7E-34 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1994 73065aa8a0dddf4278b189cc74100678 247 Pfam PF00486 Transcriptional regulatory protein, C terminal 170 236 6.3E-13 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_1994 73065aa8a0dddf4278b189cc74100678 247 SMART SM00862 170 236 4.2E-17 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_1994 73065aa8a0dddf4278b189cc74100678 247 SUPERFAMILY SSF52172 24 142 1.85E-35 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1994 73065aa8a0dddf4278b189cc74100678 247 Gene3D G3DSA:1.10.10.10 149 244 1.1E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1994 73065aa8a0dddf4278b189cc74100678 247 Gene3D G3DSA:3.40.50.2300 11 145 5.3E-34 T 14-10-2018 Tharo_1994 73065aa8a0dddf4278b189cc74100678 247 Pfam PF00072 Response regulator receiver domain 26 135 7.0E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_0970 c9b43970e3c6fa8ccadef3cb94d4eeec 108 PRINTS PR01853 Bacterial YajC preprotein translocase signature 58 76 8.7E-16 T 14-10-2018 IPR003849 Preprotein translocase YajC Tharo_0970 c9b43970e3c6fa8ccadef3cb94d4eeec 108 PRINTS PR01853 Bacterial YajC preprotein translocase signature 20 40 8.7E-16 T 14-10-2018 IPR003849 Preprotein translocase YajC Tharo_0970 c9b43970e3c6fa8ccadef3cb94d4eeec 108 Pfam PF02699 Preprotein translocase subunit 22 97 1.5E-29 T 14-10-2018 IPR003849 Preprotein translocase YajC Tharo_0970 c9b43970e3c6fa8ccadef3cb94d4eeec 108 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 20 100 1.0E-28 T 14-10-2018 IPR003849 Preprotein translocase YajC Tharo_0970 c9b43970e3c6fa8ccadef3cb94d4eeec 108 SMART SM01323 18 100 5.2E-44 T 14-10-2018 IPR003849 Preprotein translocase YajC Tharo_0026 d9270fc8947a6117954154ebbe7b51e2 338 Gene3D G3DSA:3.30.750.80 4 78 1.5E-10 T 14-10-2018 Tharo_0026 d9270fc8947a6117954154ebbe7b51e2 338 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 32 214 2.4E-24 T 14-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 Tharo_0026 d9270fc8947a6117954154ebbe7b51e2 338 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 239 336 2.7E-6 T 14-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 Tharo_0026 d9270fc8947a6117954154ebbe7b51e2 338 SUPERFAMILY SSF53335 16 323 2.51E-47 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_0026 d9270fc8947a6117954154ebbe7b51e2 338 Gene3D G3DSA:3.40.50.150 112 338 3.5E-44 T 14-10-2018 Tharo_0544 e2a394b5553d89a7703f12b9bebc1fa6 646 Gene3D G3DSA:2.130.10.10 65 535 2.3E-181 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Tharo_0544 e2a394b5553d89a7703f12b9bebc1fa6 646 TIGRFAM TIGR04244 nitrous_NosZ_RR: nitrous-oxide reductase, TAT-dependent 15 645 9.6E-299 T 14-10-2018 IPR023644 Nitrous-oxide reductase GO:0005507|GO:0005509|GO:0050304|GO:0055114 KEGG: 00910+1.7.2.4|MetaCyc: PWY-6748|MetaCyc: PWY-7084 Tharo_0544 e2a394b5553d89a7703f12b9bebc1fa6 646 SUPERFAMILY SSF49503 513 645 4.18E-31 T 14-10-2018 IPR008972 Cupredoxin Tharo_0544 e2a394b5553d89a7703f12b9bebc1fa6 646 Gene3D G3DSA:2.60.40.420 536 646 8.7E-33 T 14-10-2018 IPR008972 Cupredoxin Tharo_0544 e2a394b5553d89a7703f12b9bebc1fa6 646 SUPERFAMILY SSF50974 68 521 2.49E-112 T 14-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 Tharo_0544 e2a394b5553d89a7703f12b9bebc1fa6 646 Pfam PF13473 Cupredoxin-like domain 551 628 1.9E-7 T 14-10-2018 IPR028096 EfeO-type cupredoxin-like domain Tharo_1488 e25716101153283792fead3d0b336679 370 SUPERFAMILY SSF52540 65 204 6.76E-14 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1488 e25716101153283792fead3d0b336679 370 Pfam PF03969 AFG1-like ATPase 15 364 3.8E-126 T 14-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 Tharo_1488 e25716101153283792fead3d0b336679 370 Gene3D G3DSA:3.40.50.300 21 186 1.7E-20 T 14-10-2018 Tharo_0391 86ac796ba092cc74f583356e2347f40d 454 Gene3D G3DSA:3.30.750.140 366 449 2.3E-6 T 14-10-2018 IPR038610 FliK-like, C-terminal domain superfamily Tharo_0391 86ac796ba092cc74f583356e2347f40d 454 Pfam PF02120 Flagellar hook-length control protein FliK 364 441 1.6E-12 T 14-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal Tharo_1315 39f58e05cb464b199a2687614f7a0e4f 604 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 579 601 2.3E-10 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal Tharo_1315 39f58e05cb464b199a2687614f7a0e4f 604 Gene3D G3DSA:3.40.50.300 353 602 8.7E-57 T 14-10-2018 Tharo_1315 39f58e05cb464b199a2687614f7a0e4f 604 Pfam PF02653 Branched-chain amino acid transport system / permease component 30 309 6.3E-35 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Tharo_1315 39f58e05cb464b199a2687614f7a0e4f 604 SMART SM00382 381 579 1.8E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1315 39f58e05cb464b199a2687614f7a0e4f 604 SUPERFAMILY SSF52540 356 600 1.81E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1315 39f58e05cb464b199a2687614f7a0e4f 604 Pfam PF00005 ABC transporter 373 530 3.4E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_0074 e1e3b48e31f04bf9ff089e8f6f67bf15 118 Pfam PF03334 Na+/H+ antiporter subunit 18 98 2.9E-20 T 14-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 Tharo_0074 e1e3b48e31f04bf9ff089e8f6f67bf15 118 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 18 106 1.2E-20 T 14-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 Tharo_1509 95788dc6fd733c1fbe24b0000f6c2eb9 224 Gene3D G3DSA:1.25.40.20 116 208 2.2E-19 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily Tharo_1509 95788dc6fd733c1fbe24b0000f6c2eb9 224 Gene3D G3DSA:1.25.40.20 20 115 2.3E-21 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily Tharo_1509 95788dc6fd733c1fbe24b0000f6c2eb9 224 SMART SM00248 88 117 5.2E-4 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 Tharo_1509 95788dc6fd733c1fbe24b0000f6c2eb9 224 SMART SM00248 55 84 4.1 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 Tharo_1509 95788dc6fd733c1fbe24b0000f6c2eb9 224 SMART SM00248 151 181 1.6 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 Tharo_1509 95788dc6fd733c1fbe24b0000f6c2eb9 224 SMART SM00248 118 147 0.0022 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 Tharo_1509 95788dc6fd733c1fbe24b0000f6c2eb9 224 Pfam PF12796 Ankyrin repeats (3 copies) 29 117 1.2E-11 T 14-10-2018 IPR020683 Ankyrin repeat-containing domain Tharo_1509 95788dc6fd733c1fbe24b0000f6c2eb9 224 Pfam PF12796 Ankyrin repeats (3 copies) 123 204 6.6E-9 T 14-10-2018 IPR020683 Ankyrin repeat-containing domain Tharo_1509 95788dc6fd733c1fbe24b0000f6c2eb9 224 SUPERFAMILY SSF48403 29 205 4.23E-38 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily Tharo_0140 6515fe0180519d207915e8ded1646d17 380 Pfam PF01098 Cell cycle protein 24 374 3.2E-103 T 14-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_0140 6515fe0180519d207915e8ded1646d17 380 Hamap MF_02079 Peptidoglycan glycosyltransferase MrdB [mrdB]. 14 378 26.494 T 14-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_0140 6515fe0180519d207915e8ded1646d17 380 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 333 357 - T 14-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_0140 6515fe0180519d207915e8ded1646d17 380 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 20 375 1.2E-125 T 14-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_2346 124a48db02c690761b0d2e0d94ab7e8d 460 SMART SM00448 9 120 4.4E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2346 124a48db02c690761b0d2e0d94ab7e8d 460 Gene3D G3DSA:1.10.10.60 399 447 5.5E-9 T 14-10-2018 Tharo_2346 124a48db02c690761b0d2e0d94ab7e8d 460 Gene3D G3DSA:3.40.50.2300 7 133 1.6E-32 T 14-10-2018 Tharo_2346 124a48db02c690761b0d2e0d94ab7e8d 460 Pfam PF00158 Sigma-54 interaction domain 145 311 6.7E-67 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Tharo_2346 124a48db02c690761b0d2e0d94ab7e8d 460 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 169 182 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Tharo_2346 124a48db02c690761b0d2e0d94ab7e8d 460 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 358 367 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Tharo_2346 124a48db02c690761b0d2e0d94ab7e8d 460 SUPERFAMILY SSF46689 401 446 3.18E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_2346 124a48db02c690761b0d2e0d94ab7e8d 460 Gene3D G3DSA:1.10.8.60 316 395 2.9E-24 T 14-10-2018 Tharo_2346 124a48db02c690761b0d2e0d94ab7e8d 460 SUPERFAMILY SSF52540 145 386 1.11E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2346 124a48db02c690761b0d2e0d94ab7e8d 460 SMART SM00382 165 308 7.3E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2346 124a48db02c690761b0d2e0d94ab7e8d 460 Gene3D G3DSA:3.40.50.300 138 315 3.9E-61 T 14-10-2018 Tharo_2346 124a48db02c690761b0d2e0d94ab7e8d 460 SUPERFAMILY SSF52172 8 188 1.2E-38 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_2346 124a48db02c690761b0d2e0d94ab7e8d 460 Pfam PF00072 Response regulator receiver domain 12 120 1.2E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_0293 755e2541f2eccfff7d3ae6f46505d647 114 SMART SM00342 32 114 2.8E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Tharo_0293 755e2541f2eccfff7d3ae6f46505d647 114 Gene3D G3DSA:1.10.10.60 12 114 2.7E-25 T 14-10-2018 Tharo_0293 755e2541f2eccfff7d3ae6f46505d647 114 Pfam PF12833 Helix-turn-helix domain 38 114 4.9E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Tharo_0293 755e2541f2eccfff7d3ae6f46505d647 114 SUPERFAMILY SSF46689 68 114 3.58E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_0293 755e2541f2eccfff7d3ae6f46505d647 114 SUPERFAMILY SSF46689 15 66 1.61E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_1652 8fe9f6c2998433f67f050cc6c3815d3b 280 Hamap MF_01527_B GTP cyclohydrolase FolE2 [folE2]. 20 275 38.365 T 14-10-2018 IPR022838 GTP cyclohydrolase FolE2 GO:0003934|GO:0035998 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 Tharo_1652 8fe9f6c2998433f67f050cc6c3815d3b 280 Gene3D G3DSA:3.10.270.10 31 279 3.6E-100 T 14-10-2018 Tharo_1652 8fe9f6c2998433f67f050cc6c3815d3b 280 Pfam PF02649 Type I GTP cyclohydrolase folE2 20 270 3.0E-98 T 14-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 Tharo_3143 91bd912ea2a8c5ab788a2c8deac6d463 313 SUPERFAMILY SSF48179 175 298 4.08E-32 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Tharo_3143 91bd912ea2a8c5ab788a2c8deac6d463 313 Gene3D G3DSA:1.10.1040.10 176 303 6.7E-43 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Tharo_3143 91bd912ea2a8c5ab788a2c8deac6d463 313 SUPERFAMILY SSF51735 6 176 6.9E-21 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_3143 91bd912ea2a8c5ab788a2c8deac6d463 313 Gene3D G3DSA:3.40.50.720 7 175 2.8E-58 T 14-10-2018 Tharo_3143 91bd912ea2a8c5ab788a2c8deac6d463 313 Pfam PF02558 Ketopantoate reductase PanE/ApbA 8 154 5.3E-39 T 14-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain Tharo_3143 91bd912ea2a8c5ab788a2c8deac6d463 313 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 175 298 7.8E-33 T 14-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain Tharo_3143 91bd912ea2a8c5ab788a2c8deac6d463 313 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 7 299 1.1E-81 T 14-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 Tharo_0847 e7428a9e6f673c66944125c8cc25b878 302 PIRSF PIRSF018296 2 302 1.6E-81 T 14-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 Tharo_0847 e7428a9e6f673c66944125c8cc25b878 302 Gene3D G3DSA:3.90.1670.10 15 302 4.4E-84 T 14-10-2018 IPR024064 FdhE-like superfamily Tharo_0847 e7428a9e6f673c66944125c8cc25b878 302 SUPERFAMILY SSF144020 17 299 1.23E-80 T 14-10-2018 IPR024064 FdhE-like superfamily Tharo_0847 e7428a9e6f673c66944125c8cc25b878 302 Pfam PF04216 Protein involved in formate dehydrogenase formation 13 297 2.3E-90 T 14-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 Tharo_0847 e7428a9e6f673c66944125c8cc25b878 302 TIGRFAM TIGR01562 FdhE: formate dehydrogenase accessory protein FdhE 10 299 2.0E-67 T 14-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 Tharo_0847 e7428a9e6f673c66944125c8cc25b878 302 Hamap MF_00611 Protein FdhE [fdhE]. 2 300 30.709 T 14-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 Tharo_2991 98bc79d2d92817c10bbb09f23f5a9ebf 260 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 29 38 - T 14-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Tharo_2991 98bc79d2d92817c10bbb09f23f5a9ebf 260 Gene3D G3DSA:3.60.10.10 1 259 1.0E-84 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Tharo_2991 98bc79d2d92817c10bbb09f23f5a9ebf 260 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 2 254 2.3E-69 T 14-10-2018 Tharo_2991 98bc79d2d92817c10bbb09f23f5a9ebf 260 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 249 8.6E-22 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase Tharo_2991 98bc79d2d92817c10bbb09f23f5a9ebf 260 SUPERFAMILY SSF56219 2 257 2.88E-76 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Tharo_2991 98bc79d2d92817c10bbb09f23f5a9ebf 260 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 2 256 4.0E-77 T 14-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 Tharo_2445 3463b10ced91ab9fff2dea9ce216f3a5 234 SUPERFAMILY SSF46785 160 226 9.1E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_2445 3463b10ced91ab9fff2dea9ce216f3a5 234 SUPERFAMILY SSF51206 20 157 3.27E-25 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like Tharo_2445 3463b10ced91ab9fff2dea9ce216f3a5 234 Pfam PF00027 Cyclic nucleotide-binding domain 43 130 1.5E-9 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Tharo_2445 3463b10ced91ab9fff2dea9ce216f3a5 234 Gene3D G3DSA:2.60.120.10 16 155 7.1E-42 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Tharo_2445 3463b10ced91ab9fff2dea9ce216f3a5 234 Pfam PF13545 Crp-like helix-turn-helix domain 162 223 2.5E-13 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Tharo_2445 3463b10ced91ab9fff2dea9ce216f3a5 234 Gene3D G3DSA:1.10.10.10 156 225 1.3E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2445 3463b10ced91ab9fff2dea9ce216f3a5 234 SMART SM00419 169 217 1.5E-9 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Tharo_2691 c648228705ae71507f56d1ac2f798cb1 128 Pfam PF01903 CbiX 16 119 3.2E-25 T 14-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 Tharo_2691 c648228705ae71507f56d1ac2f798cb1 128 Gene3D G3DSA:3.40.50.1400 7 127 8.9E-29 T 14-10-2018 Tharo_2691 c648228705ae71507f56d1ac2f798cb1 128 SUPERFAMILY SSF53800 9 126 3.4E-29 T 14-10-2018 Tharo_3304 9466143e919991dfacd1b44bc4a0f1b3 411 Gene3D G3DSA:2.40.30.10 186 342 3.4E-67 T 14-10-2018 Tharo_3304 9466143e919991dfacd1b44bc4a0f1b3 411 Gene3D G3DSA:1.10.8.260 270 325 3.4E-67 T 14-10-2018 IPR023166 HI0933-like insert domain superfamily Tharo_3304 9466143e919991dfacd1b44bc4a0f1b3 411 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 1 394 1.1E-86 T 14-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like Tharo_3304 9466143e919991dfacd1b44bc4a0f1b3 411 Pfam PF03486 HI0933-like protein 1 394 1.2E-108 T 14-10-2018 Tharo_3304 9466143e919991dfacd1b44bc4a0f1b3 411 SUPERFAMILY SSF51905 1 396 3.4E-44 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_3304 9466143e919991dfacd1b44bc4a0f1b3 411 TIGRFAM TIGR03862 flavo_PP4765: flavoprotein, TIGR03862 family 19 401 2.0E-166 T 14-10-2018 IPR022460 Conserved hyptotheical protein CHP03862, flavoprotein, PP4765 Tharo_3304 9466143e919991dfacd1b44bc4a0f1b3 411 Gene3D G3DSA:3.50.50.60 1 393 3.4E-67 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_3304 9466143e919991dfacd1b44bc4a0f1b3 411 SUPERFAMILY SSF160996 187 341 6.8E-12 T 14-10-2018 Tharo_1530 a35c66fa49d66782e3fc6fd55b653bb0 282 Pfam PF00756 Putative esterase 23 273 1.1E-63 T 14-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 Tharo_1530 a35c66fa49d66782e3fc6fd55b653bb0 282 SUPERFAMILY SSF53474 3 279 1.22E-94 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_1530 a35c66fa49d66782e3fc6fd55b653bb0 282 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 4 279 1.3E-131 T 14-10-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 Tharo_1530 a35c66fa49d66782e3fc6fd55b653bb0 282 Gene3D G3DSA:3.40.50.1820 4 281 6.0E-96 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_3191 c382f624b4220b615b29086ee0a55439 118 SUPERFAMILY SSF81301 1 110 6.05E-36 T 14-10-2018 Tharo_3191 c382f624b4220b615b29086ee0a55439 118 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 7 104 9.9E-35 T 14-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS Tharo_3191 c382f624b4220b615b29086ee0a55439 118 Gene3D G3DSA:3.30.460.10 1 116 3.4E-36 T 14-10-2018 Tharo_3191 c382f624b4220b615b29086ee0a55439 118 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 23.194 T 14-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS Tharo_3191 c382f624b4220b615b29086ee0a55439 118 Pfam PF02410 Ribosomal silencing factor during starvation 10 104 1.4E-25 T 14-10-2018 Tharo_0443 3f80c966440e578220bff971378de2fb 522 SUPERFAMILY SSF58104 218 498 4.32E-66 T 14-10-2018 Tharo_0443 3f80c966440e578220bff971378de2fb 522 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 349 376 1.6E-48 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_0443 3f80c966440e578220bff971378de2fb 522 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 378 407 1.6E-48 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_0443 3f80c966440e578220bff971378de2fb 522 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 426 455 1.6E-48 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_0443 3f80c966440e578220bff971378de2fb 522 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 272 301 1.6E-48 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_0443 3f80c966440e578220bff971378de2fb 522 SMART SM00283 251 497 4.1E-76 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_0443 3f80c966440e578220bff971378de2fb 522 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 309 466 2.3E-49 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_0443 3f80c966440e578220bff971378de2fb 522 Gene3D G3DSA:1.10.287.950 198 499 2.2E-82 T 14-10-2018 Tharo_0443 3f80c966440e578220bff971378de2fb 522 SMART SM00304 198 250 7.6E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_0859 0f5aff6416075370c2a2fe5ee93d1124 200 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 47 186 4.5E-26 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 Tharo_0859 0f5aff6416075370c2a2fe5ee93d1124 200 SUPERFAMILY SSF55846 31 198 2.49E-62 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 Tharo_0859 0f5aff6416075370c2a2fe5ee93d1124 200 SMART SM00644 37 185 2.5E-49 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 Tharo_0859 0f5aff6416075370c2a2fe5ee93d1124 200 Gene3D G3DSA:3.40.80.10 26 200 2.0E-56 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 Tharo_3137 65737978cbe30037533053d18f9d4ce7 416 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 120 144 7.7E-21 T 14-10-2018 Tharo_3137 65737978cbe30037533053d18f9d4ce7 416 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 83 95 7.7E-21 T 14-10-2018 Tharo_3137 65737978cbe30037533053d18f9d4ce7 416 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 38 52 7.7E-21 T 14-10-2018 Tharo_3137 65737978cbe30037533053d18f9d4ce7 416 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 16 32 7.7E-21 T 14-10-2018 Tharo_3137 65737978cbe30037533053d18f9d4ce7 416 Gene3D G3DSA:3.40.50.150 18 204 9.6E-34 T 14-10-2018 Tharo_3137 65737978cbe30037533053d18f9d4ce7 416 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 86 92 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Tharo_3137 65737978cbe30037533053d18f9d4ce7 416 Pfam PF07669 Eco57I restriction-modification methylase 82 181 5.7E-8 T 14-10-2018 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 Tharo_3137 65737978cbe30037533053d18f9d4ce7 416 SUPERFAMILY SSF53335 14 195 2.81E-32 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_3440 3fa27b19c2aaf58034fa6b6460a61e7f 166 SUPERFAMILY SSF55729 9 155 1.36E-26 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Tharo_3440 3fa27b19c2aaf58034fa6b6460a61e7f 166 Gene3D G3DSA:3.40.630.30 3 153 1.1E-32 T 14-10-2018 Tharo_3440 3fa27b19c2aaf58034fa6b6460a61e7f 166 Pfam PF00583 Acetyltransferase (GNAT) family 31 143 3.3E-14 T 14-10-2018 IPR000182 GNAT domain Tharo_0997 90e8184fae713a6e7dd82cd1b92d2ea2 381 SUPERFAMILY SSF52540 197 362 1.21E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0997 90e8184fae713a6e7dd82cd1b92d2ea2 381 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 266 284 2.7E-8 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_0997 90e8184fae713a6e7dd82cd1b92d2ea2 381 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 200 220 2.7E-8 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_0997 90e8184fae713a6e7dd82cd1b92d2ea2 381 Hamap MF_00900 GTPase HflX [hflX]. 27 381 45.801 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 Tharo_0997 90e8184fae713a6e7dd82cd1b92d2ea2 381 PIRSF PIRSF006809 3 373 5.7E-138 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 Tharo_0997 90e8184fae713a6e7dd82cd1b92d2ea2 381 Pfam PF01926 50S ribosome-binding GTPase 200 317 1.6E-20 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_0997 90e8184fae713a6e7dd82cd1b92d2ea2 381 Pfam PF13167 GTP-binding GTPase N-terminal 25 112 6.0E-30 T 14-10-2018 IPR025121 GTPase HflX, N-terminal Tharo_0997 90e8184fae713a6e7dd82cd1b92d2ea2 381 Gene3D G3DSA:3.40.50.11060 18 138 7.2E-39 T 14-10-2018 Tharo_0997 90e8184fae713a6e7dd82cd1b92d2ea2 381 Pfam PF16360 GTP-binding GTPase Middle Region 114 192 6.5E-28 T 14-10-2018 IPR032305 GTP-binding protein, middle domain Tharo_0997 90e8184fae713a6e7dd82cd1b92d2ea2 381 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 10 357 5.8E-148 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 Tharo_0997 90e8184fae713a6e7dd82cd1b92d2ea2 381 Gene3D G3DSA:3.40.50.300 199 365 1.1E-40 T 14-10-2018 Tharo_1836 c1fff28cb0c71642be505d7c258f8ddc 316 Pfam PF16868 NMT1-like family 30 313 2.4E-94 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family Tharo_1836 c1fff28cb0c71642be505d7c258f8ddc 316 SUPERFAMILY SSF53850 25 315 1.95E-74 T 14-10-2018 Tharo_1836 c1fff28cb0c71642be505d7c258f8ddc 316 Gene3D G3DSA:3.40.190.10 30 313 6.5E-99 T 14-10-2018 Tharo_1836 c1fff28cb0c71642be505d7c258f8ddc 316 Gene3D G3DSA:3.40.190.10 114 250 6.5E-99 T 14-10-2018 Tharo_1836 c1fff28cb0c71642be505d7c258f8ddc 316 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 1 313 8.5E-113 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family Tharo_0153 63ef3be0d7c3f4bfe5dcf3a03879ccc8 396 Gene3D G3DSA:1.10.150.130 72 171 2.5E-8 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Tharo_0153 63ef3be0d7c3f4bfe5dcf3a03879ccc8 396 Gene3D G3DSA:1.10.443.10 172 368 7.7E-37 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Tharo_0153 63ef3be0d7c3f4bfe5dcf3a03879ccc8 396 SUPERFAMILY SSF56349 72 360 7.65E-51 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Tharo_0153 63ef3be0d7c3f4bfe5dcf3a03879ccc8 396 Pfam PF00589 Phage integrase family 189 351 5.6E-17 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Tharo_0153 63ef3be0d7c3f4bfe5dcf3a03879ccc8 396 Pfam PF12167 Arm DNA-binding domain 1 37 8.8E-12 T 14-10-2018 IPR022000 Min27-like integrase, DNA-binding domain Tharo_1311 755d5b2321f15d92c92ab637c1d92777 181 Pfam PF00583 Acetyltransferase (GNAT) family 77 168 1.3E-9 T 14-10-2018 IPR000182 GNAT domain Tharo_1311 755d5b2321f15d92c92ab637c1d92777 181 SUPERFAMILY SSF55729 25 170 2.44E-19 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Tharo_1311 755d5b2321f15d92c92ab637c1d92777 181 Gene3D G3DSA:3.40.630.30 39 179 4.5E-22 T 14-10-2018 Tharo_2631 4e5dffdc0db4c8bd0230c52afa1c3b64 665 Pfam PF00593 TonB dependent receptor 201 661 2.6E-36 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Tharo_2631 4e5dffdc0db4c8bd0230c52afa1c3b64 665 TIGRFAM TIGR01778 TonB-copper: TonB-dependent copper receptor 46 661 1.5E-213 T 14-10-2018 IPR010100 TonB-dependent copper receptor Tharo_2631 4e5dffdc0db4c8bd0230c52afa1c3b64 665 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 144 8.2E-14 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain Tharo_2631 4e5dffdc0db4c8bd0230c52afa1c3b64 665 Gene3D G3DSA:2.40.170.20 151 663 1.6E-69 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Tharo_2631 4e5dffdc0db4c8bd0230c52afa1c3b64 665 Gene3D G3DSA:2.170.130.10 36 150 4.9E-15 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Tharo_2631 4e5dffdc0db4c8bd0230c52afa1c3b64 665 SUPERFAMILY SSF56935 23 661 5.5E-89 T 14-10-2018 Tharo_0175 f780a24edd390f74d5a34e1b66b28488 817 SUPERFAMILY SSF82866 570 787 4.19E-32 T 14-10-2018 Tharo_0175 f780a24edd390f74d5a34e1b66b28488 817 Gene3D G3DSA:1.20.1640.10 587 792 1.7E-9 T 14-10-2018 Tharo_0175 f780a24edd390f74d5a34e1b66b28488 817 Pfam PF03176 MMPL family 209 432 5.0E-5 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 Tharo_0175 f780a24edd390f74d5a34e1b66b28488 817 Pfam PF03176 MMPL family 586 782 3.3E-13 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 Tharo_0175 f780a24edd390f74d5a34e1b66b28488 817 SUPERFAMILY SSF82866 197 394 2.75E-25 T 14-10-2018 Tharo_2829 97900aa33f855e061e0d4ca59c38cca6 264 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 6 262 19.022 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 Tharo_2829 97900aa33f855e061e0d4ca59c38cca6 264 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 4 256 1.3E-76 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 Tharo_2829 97900aa33f855e061e0d4ca59c38cca6 264 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 139 151 - T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 Tharo_2829 97900aa33f855e061e0d4ca59c38cca6 264 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 9 255 2.0E-77 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 Tharo_1117 11d2109d43171a023a7fd5a242de9e2b 304 SUPERFAMILY SSF48498 194 302 1.07E-7 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Tharo_1117 11d2109d43171a023a7fd5a242de9e2b 304 SUPERFAMILY SSF46689 122 198 6.98E-20 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_1117 11d2109d43171a023a7fd5a242de9e2b 304 Gene3D G3DSA:1.10.357.10 170 303 9.4E-24 T 14-10-2018 Tharo_1117 11d2109d43171a023a7fd5a242de9e2b 304 Gene3D G3DSA:1.10.10.60 114 169 5.6E-19 T 14-10-2018 Tharo_1117 11d2109d43171a023a7fd5a242de9e2b 304 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 127 140 2.0E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_1117 11d2109d43171a023a7fd5a242de9e2b 304 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 148 171 2.0E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_1117 11d2109d43171a023a7fd5a242de9e2b 304 Pfam PF00440 Bacterial regulatory proteins, tetR family 127 173 6.0E-19 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_3201 bcd411ced5720d53f7375c8429cb026a 215 SUPERFAMILY SSF55781 155 212 8.13E-5 T 14-10-2018 Tharo_3201 bcd411ced5720d53f7375c8429cb026a 215 Pfam PF04340 Protein of unknown function, DUF484 2 212 5.3E-42 T 14-10-2018 IPR007435 Protein of unknown function DUF484 Tharo_3201 bcd411ced5720d53f7375c8429cb026a 215 Gene3D G3DSA:3.30.450.40 37 213 5.4E-52 T 14-10-2018 IPR029016 GAF-like domain superfamily Tharo_0378 dc69597240f996068f0a7182096cc3ff 82 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 1 75 9.0E-27 T 14-10-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system Tharo_0378 dc69597240f996068f0a7182096cc3ff 82 SUPERFAMILY SSF47598 42 74 7.04E-5 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Tharo_2399 6e9854faa598c52ccfe3c194fd0cac6a 215 TIGRFAM TIGR01993 Pyr-5-nucltdase: pyrimidine 5'-nucleotidase 6 186 1.6E-54 T 14-10-2018 IPR010237 Pyrimidine 5-nucleotidase Tharo_2399 6e9854faa598c52ccfe3c194fd0cac6a 215 Gene3D G3DSA:1.10.150.450 9 75 1.4E-9 T 14-10-2018 Tharo_2399 6e9854faa598c52ccfe3c194fd0cac6a 215 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 6 186 6.0E-18 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Tharo_2399 6e9854faa598c52ccfe3c194fd0cac6a 215 SUPERFAMILY SSF56784 6 210 7.67E-35 T 14-10-2018 IPR036412 HAD-like superfamily Tharo_2399 6e9854faa598c52ccfe3c194fd0cac6a 215 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 186 2.7E-13 T 14-10-2018 Tharo_2399 6e9854faa598c52ccfe3c194fd0cac6a 215 Gene3D G3DSA:3.40.50.1000 76 213 1.4E-25 T 14-10-2018 IPR023214 HAD superfamily Tharo_0700 4ee109ff529361f5a92723bc4f7ff726 312 Pfam PF11920 Protein of unknown function (DUF3438) 16 291 1.1E-125 T 14-10-2018 IPR021844 Integrating conjugative element protein, PFL4704 Tharo_0700 4ee109ff529361f5a92723bc4f7ff726 312 TIGRFAM TIGR03749 conj_TIGR03749: integrating conjugative element protein, PFL_4704 family 19 282 6.5E-112 T 14-10-2018 IPR021844 Integrating conjugative element protein, PFL4704 Tharo_1028 6ed0a136c63d3eb24092469254b514f2 197 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 94.643 T 14-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 Tharo_1028 6ed0a136c63d3eb24092469254b514f2 197 Pfam PF13662 Toprim domain 80 169 2.9E-21 T 14-10-2018 IPR006171 TOPRIM domain Tharo_1028 6ed0a136c63d3eb24092469254b514f2 197 Gene3D G3DSA:3.40.1360.10 76 197 3.2E-39 T 14-10-2018 Tharo_1028 6ed0a136c63d3eb24092469254b514f2 197 SUPERFAMILY SSF111304 2 196 1.57E-69 T 14-10-2018 IPR023627 Recombination protein RecR Tharo_1028 6ed0a136c63d3eb24092469254b514f2 197 TIGRFAM TIGR00615 recR: recombination protein RecR 2 195 2.4E-66 T 14-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 Tharo_1028 6ed0a136c63d3eb24092469254b514f2 197 Pfam PF02132 RecR protein 39 77 4.7E-13 T 14-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger Tharo_1028 6ed0a136c63d3eb24092469254b514f2 197 SMART SM00493 79 164 1.9E-9 T 14-10-2018 IPR006171 TOPRIM domain Tharo_1028 6ed0a136c63d3eb24092469254b514f2 197 Gene3D G3DSA:1.10.8.420 1 51 3.2E-19 T 14-10-2018 Tharo_1274 eab8f6c1c4ba3d5093a070b49be6f064 200 Pfam PF01106 NifU-like domain 132 197 2.6E-16 T 14-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 Tharo_1274 eab8f6c1c4ba3d5093a070b49be6f064 200 Gene3D G3DSA:3.30.1370.70 4 93 3.7E-14 T 14-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily Tharo_1274 eab8f6c1c4ba3d5093a070b49be6f064 200 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 138 198 2.0E-10 T 14-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 Tharo_1274 eab8f6c1c4ba3d5093a070b49be6f064 200 SMART SM00932 5 91 2.6E-7 T 14-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal Tharo_1274 eab8f6c1c4ba3d5093a070b49be6f064 200 SUPERFAMILY SSF110836 7 87 1.18E-15 T 14-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily Tharo_1274 eab8f6c1c4ba3d5093a070b49be6f064 200 Gene3D G3DSA:3.30.300.130 126 198 4.3E-16 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Tharo_1274 eab8f6c1c4ba3d5093a070b49be6f064 200 SUPERFAMILY SSF117916 120 198 3.27E-18 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Tharo_1274 eab8f6c1c4ba3d5093a070b49be6f064 200 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 8 87 6.3E-16 T 14-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal Tharo_0827 9c38f9a60a904ffabc3b3a01c2d61ab6 722 SMART SM00965 309 357 1.0E-9 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 Tharo_0827 9c38f9a60a904ffabc3b3a01c2d61ab6 722 PRINTS PR00811 Bacterial general secretion pathway protein D signature 680 698 1.4E-20 T 14-10-2018 IPR001775 GspD/PilQ family Tharo_0827 9c38f9a60a904ffabc3b3a01c2d61ab6 722 PRINTS PR00811 Bacterial general secretion pathway protein D signature 703 717 1.4E-20 T 14-10-2018 IPR001775 GspD/PilQ family Tharo_0827 9c38f9a60a904ffabc3b3a01c2d61ab6 722 PRINTS PR00811 Bacterial general secretion pathway protein D signature 555 579 1.4E-20 T 14-10-2018 IPR001775 GspD/PilQ family Tharo_0827 9c38f9a60a904ffabc3b3a01c2d61ab6 722 PRINTS PR00811 Bacterial general secretion pathway protein D signature 447 457 1.4E-20 T 14-10-2018 IPR001775 GspD/PilQ family Tharo_0827 9c38f9a60a904ffabc3b3a01c2d61ab6 722 Gene3D G3DSA:3.30.1370.120 381 444 1.9E-7 T 14-10-2018 IPR038591 NolW-like superfamily Tharo_0827 9c38f9a60a904ffabc3b3a01c2d61ab6 722 Pfam PF00263 Bacterial type II and III secretion system protein 559 715 1.6E-48 T 14-10-2018 IPR004846 Type II/III secretion system GO:0009306 Tharo_0827 9c38f9a60a904ffabc3b3a01c2d61ab6 722 Pfam PF03958 Bacterial type II/III secretion system short domain 383 447 9.1E-10 T 14-10-2018 IPR005644 NolW-like Tharo_0827 9c38f9a60a904ffabc3b3a01c2d61ab6 722 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 661 694 - T 14-10-2018 IPR004845 Type II secretion system GspD, conserved site GO:0008565 Tharo_0827 9c38f9a60a904ffabc3b3a01c2d61ab6 722 Gene3D G3DSA:2.60.40.3470 151 265 2.1E-34 T 14-10-2018 Tharo_0827 9c38f9a60a904ffabc3b3a01c2d61ab6 722 TIGRFAM TIGR02515 IV_pilus_PilQ: type IV pilus secretin PilQ 284 715 6.0E-153 T 14-10-2018 IPR013355 Type IV pilus secretin PilQ Tharo_0827 9c38f9a60a904ffabc3b3a01c2d61ab6 722 Pfam PF07660 Secretin and TonB N terminus short domain 309 355 3.9E-10 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 Tharo_0827 9c38f9a60a904ffabc3b3a01c2d61ab6 722 Gene3D G3DSA:3.55.50.30 266 380 1.3E-44 T 14-10-2018 Tharo_0651 dd465b0dedc6aa5730e4930d94e1b03d 386 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 3.8E-156 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Tharo_0651 dd465b0dedc6aa5730e4930d94e1b03d 386 PIRSF PIRSF001554 1 386 3.3E-147 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Tharo_0651 dd465b0dedc6aa5730e4930d94e1b03d 386 Gene3D G3DSA:3.30.470.20 1 234 1.8E-92 T 14-10-2018 Tharo_0651 dd465b0dedc6aa5730e4930d94e1b03d 386 Pfam PF08442 ATP-grasp domain 2 202 1.1E-77 T 14-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Tharo_0651 dd465b0dedc6aa5730e4930d94e1b03d 386 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 42.698 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Tharo_0651 dd465b0dedc6aa5730e4930d94e1b03d 386 SUPERFAMILY SSF56059 1 238 4.52E-81 T 14-10-2018 Tharo_0651 dd465b0dedc6aa5730e4930d94e1b03d 386 Pfam PF00549 CoA-ligase 262 381 7.4E-27 T 14-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_0651 dd465b0dedc6aa5730e4930d94e1b03d 386 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 281 - T 14-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_0651 dd465b0dedc6aa5730e4930d94e1b03d 386 SUPERFAMILY SSF52210 242 385 2.75E-53 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_0651 dd465b0dedc6aa5730e4930d94e1b03d 386 Gene3D G3DSA:3.40.50.261 240 386 8.8E-57 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Tharo_0651 dd465b0dedc6aa5730e4930d94e1b03d 386 Gene3D G3DSA:3.30.1490.20 21 104 1.8E-92 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Tharo_0387 8e63ed50632473d6d5ec1437f84bd536 561 SUPERFAMILY SSF109604 359 476 5.34E-9 T 14-10-2018 Tharo_0387 8e63ed50632473d6d5ec1437f84bd536 561 Pfam PF07238 PilZ domain 117 228 7.2E-9 T 14-10-2018 IPR009875 PilZ domain GO:0035438 Tharo_0387 8e63ed50632473d6d5ec1437f84bd536 561 Gene3D G3DSA:2.40.10.220 118 233 1.6E-19 T 14-10-2018 Tharo_0387 8e63ed50632473d6d5ec1437f84bd536 561 Pfam PF13487 HD domain 413 445 2.6E-5 T 14-10-2018 Tharo_0387 8e63ed50632473d6d5ec1437f84bd536 561 Gene3D G3DSA:1.10.3210.10 321 497 3.8E-22 T 14-10-2018 Tharo_2434 b9e807d455c06a303284303775ff1953 216 Gene3D G3DSA:1.20.120.520 1 144 2.0E-19 T 14-10-2018 Tharo_2434 b9e807d455c06a303284303775ff1953 216 Pfam PF01814 Hemerythrin HHE cation binding domain 4 136 6.8E-16 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 Tharo_1896 206b04c9ea8fa6796336a4e609be8f8d 207 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 12 205 30.622 T 14-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 Tharo_1896 206b04c9ea8fa6796336a4e609be8f8d 207 Gene3D G3DSA:3.40.50.150 27 206 1.2E-61 T 14-10-2018 Tharo_1896 206b04c9ea8fa6796336a4e609be8f8d 207 PIRSF PIRSF005461 1 206 3.4E-75 T 14-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 Tharo_1896 206b04c9ea8fa6796336a4e609be8f8d 207 Pfam PF01728 FtsJ-like methyltransferase 28 203 1.8E-56 T 14-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 Tharo_1896 206b04c9ea8fa6796336a4e609be8f8d 207 SUPERFAMILY SSF53335 27 204 4.3E-42 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_1597 3c99c17b17ad389093fde718da618e54 191 Hamap MF_00528 Septum formation protein Maf [maf]. 2 190 28.996 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 Tharo_1597 3c99c17b17ad389093fde718da618e54 191 Gene3D G3DSA:3.90.950.10 2 190 3.0E-57 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Tharo_1597 3c99c17b17ad389093fde718da618e54 191 SUPERFAMILY SSF52972 1 184 6.47E-55 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Tharo_1597 3c99c17b17ad389093fde718da618e54 191 Pfam PF02545 Maf-like protein 3 184 1.5E-41 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 Tharo_1597 3c99c17b17ad389093fde718da618e54 191 TIGRFAM TIGR00172 maf: septum formation protein Maf 1 184 3.0E-49 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 Tharo_1597 3c99c17b17ad389093fde718da618e54 191 PIRSF PIRSF006305 1 190 5.1E-41 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 Tharo_2220 c671485f30b75c69e3f27f5ad22dddd6 431 SUPERFAMILY SSF81340 3 406 4.05E-85 T 14-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 Tharo_2220 c671485f30b75c69e3f27f5ad22dddd6 431 Pfam PF00654 Voltage gated chloride channel 48 392 1.3E-77 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 Tharo_2220 c671485f30b75c69e3f27f5ad22dddd6 431 Gene3D G3DSA:1.10.3080.10 1 412 2.4E-80 T 14-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 Tharo_2220 c671485f30b75c69e3f27f5ad22dddd6 431 PRINTS PR00762 Chloride channel signature 61 78 3.0E-28 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 Tharo_2220 c671485f30b75c69e3f27f5ad22dddd6 431 PRINTS PR00762 Chloride channel signature 313 333 3.0E-28 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 Tharo_2220 c671485f30b75c69e3f27f5ad22dddd6 431 PRINTS PR00762 Chloride channel signature 360 379 3.0E-28 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 Tharo_2220 c671485f30b75c69e3f27f5ad22dddd6 431 PRINTS PR00762 Chloride channel signature 95 114 3.0E-28 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 Tharo_2220 c671485f30b75c69e3f27f5ad22dddd6 431 PRINTS PR00762 Chloride channel signature 146 165 3.0E-28 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 Tharo_2220 c671485f30b75c69e3f27f5ad22dddd6 431 PRINTS PR00762 Chloride channel signature 342 358 3.0E-28 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 Tharo_0632 853ae2e4d9b3dcf2209e3d11009d5fac 416 Gene3D G3DSA:3.65.10.10 6 412 2.3E-165 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 Tharo_0632 853ae2e4d9b3dcf2209e3d11009d5fac 416 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 405 2.2E-109 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 Tharo_0632 853ae2e4d9b3dcf2209e3d11009d5fac 416 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 415 44.696 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Tharo_0632 853ae2e4d9b3dcf2209e3d11009d5fac 416 Gene3D G3DSA:3.65.10.10 21 228 2.3E-165 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 Tharo_0632 853ae2e4d9b3dcf2209e3d11009d5fac 416 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 414 2.6E-175 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Tharo_0632 853ae2e4d9b3dcf2209e3d11009d5fac 416 SUPERFAMILY SSF55205 1 415 1.8E-138 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 Tharo_2482 daec70666e3037aa8612bb88241b1b03 344 SUPERFAMILY SSF53067 101 309 6.15E-41 T 14-10-2018 Tharo_2482 daec70666e3037aa8612bb88241b1b03 344 Pfam PF00814 Glycoprotease family 24 307 1.1E-95 T 14-10-2018 IPR000905 Gcp-like domain Tharo_2482 daec70666e3037aa8612bb88241b1b03 344 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 333 63.443 T 14-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 Tharo_2482 daec70666e3037aa8612bb88241b1b03 344 Gene3D G3DSA:3.30.420.40 129 293 2.2E-124 T 14-10-2018 Tharo_2482 daec70666e3037aa8612bb88241b1b03 344 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 313 4.2E-130 T 14-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 Tharo_2482 daec70666e3037aa8612bb88241b1b03 344 Gene3D G3DSA:3.30.420.40 3 315 2.2E-124 T 14-10-2018 Tharo_2482 daec70666e3037aa8612bb88241b1b03 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 5.4E-50 T 14-10-2018 IPR017861 Kae1/TsaD family Tharo_2482 daec70666e3037aa8612bb88241b1b03 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 5.4E-50 T 14-10-2018 IPR017861 Kae1/TsaD family Tharo_2482 daec70666e3037aa8612bb88241b1b03 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 5.4E-50 T 14-10-2018 IPR017861 Kae1/TsaD family Tharo_2482 daec70666e3037aa8612bb88241b1b03 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 5.4E-50 T 14-10-2018 IPR017861 Kae1/TsaD family Tharo_2482 daec70666e3037aa8612bb88241b1b03 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 263 272 5.4E-50 T 14-10-2018 IPR017861 Kae1/TsaD family Tharo_2482 daec70666e3037aa8612bb88241b1b03 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 5.4E-50 T 14-10-2018 IPR017861 Kae1/TsaD family Tharo_2482 daec70666e3037aa8612bb88241b1b03 344 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 306 7.6E-109 T 14-10-2018 IPR017861 Kae1/TsaD family Tharo_2482 daec70666e3037aa8612bb88241b1b03 344 SUPERFAMILY SSF53067 3 121 2.01E-28 T 14-10-2018 Tharo_3125 034ff1dcf94cc99bee786c3475ae7c5a 318 TIGRFAM TIGR01380 glut_syn: glutathione synthase 5 316 3.0E-120 T 14-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 Tharo_3125 034ff1dcf94cc99bee786c3475ae7c5a 318 SUPERFAMILY SSF52440 5 126 1.78E-38 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Tharo_3125 034ff1dcf94cc99bee786c3475ae7c5a 318 SUPERFAMILY SSF56059 128 315 1.12E-55 T 14-10-2018 Tharo_3125 034ff1dcf94cc99bee786c3475ae7c5a 318 Gene3D G3DSA:3.30.470.20 119 299 1.2E-103 T 14-10-2018 Tharo_3125 034ff1dcf94cc99bee786c3475ae7c5a 318 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 5 124 4.9E-42 T 14-10-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 Tharo_3125 034ff1dcf94cc99bee786c3475ae7c5a 318 Gene3D G3DSA:3.30.1490.20 141 205 1.2E-103 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Tharo_3125 034ff1dcf94cc99bee786c3475ae7c5a 318 Gene3D G3DSA:3.40.50.20 10 118 1.2E-103 T 14-10-2018 Tharo_3125 034ff1dcf94cc99bee786c3475ae7c5a 318 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 128 301 5.0E-69 T 14-10-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 Tharo_3125 034ff1dcf94cc99bee786c3475ae7c5a 318 Hamap MF_00162 Glutathione synthetase [gshB]. 1 318 149.388 T 14-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 Tharo_2701 a912d388071ed8199588e7a0d35c232e 129 SUPERFAMILY SSF53137 14 129 9.16E-48 T 14-10-2018 Tharo_2701 a912d388071ed8199588e7a0d35c232e 129 Gene3D G3DSA:3.30.420.80 1 129 6.6E-56 T 14-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 Tharo_2701 a912d388071ed8199588e7a0d35c232e 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 129 32.619 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 Tharo_2701 a912d388071ed8199588e7a0d35c232e 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 14-10-2018 IPR018102 Ribosomal S11, conserved site Tharo_2701 a912d388071ed8199588e7a0d35c232e 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 7.3E-56 T 14-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2701 a912d388071ed8199588e7a0d35c232e 129 Pfam PF00411 Ribosomal protein S11 19 128 6.0E-50 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 Tharo_2701 a912d388071ed8199588e7a0d35c232e 129 PIRSF PIRSF002131 1 129 5.2E-53 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 Tharo_0988 7ead65bfa2e9ca67d2e3f60ba71db29b 378 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 6 367 8.4E-136 T 14-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 Tharo_0988 7ead65bfa2e9ca67d2e3f60ba71db29b 378 SUPERFAMILY SSF102114 105 323 2.22E-14 T 14-10-2018 Tharo_0988 7ead65bfa2e9ca67d2e3f60ba71db29b 378 Pfam PF04055 Radical SAM superfamily 110 289 1.2E-18 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_0988 7ead65bfa2e9ca67d2e3f60ba71db29b 378 PIRSF PIRSF006004 4 376 1.1E-153 T 14-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 Tharo_0988 7ead65bfa2e9ca67d2e3f60ba71db29b 378 Gene3D G3DSA:3.20.20.70 69 347 8.5E-108 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_0988 7ead65bfa2e9ca67d2e3f60ba71db29b 378 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 6 362 75.732 T 14-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 Tharo_0988 7ead65bfa2e9ca67d2e3f60ba71db29b 378 Gene3D G3DSA:1.10.150.530 6 67 5.6E-25 T 14-10-2018 Tharo_2305 d2287363a47276dd00effa8b48874966 541 Pfam PF03092 BT1 family 352 528 2.1E-11 T 14-10-2018 IPR039309 Biopterin transporter family Tharo_2813 822cdeb0ca1017fa9bc438a265babaaf 288 SUPERFAMILY SSF81345 11 268 5.36E-19 T 14-10-2018 IPR037294 ABC transporter, BtuC-like Tharo_2813 822cdeb0ca1017fa9bc438a265babaaf 288 Pfam PF00950 ABC 3 transport family 12 269 6.0E-50 T 14-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 Tharo_1625 e1c0eb44d7d82dcbe6760b6435efc070 293 SUPERFAMILY SSF53474 16 287 1.33E-51 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_1625 e1c0eb44d7d82dcbe6760b6435efc070 293 Pfam PF12146 Serine aminopeptidase, S33 69 185 4.6E-12 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 Tharo_1625 e1c0eb44d7d82dcbe6760b6435efc070 293 Gene3D G3DSA:3.40.50.1820 44 292 3.2E-48 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_3393 78faf3b23349174be0ac910356de9b63 294 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 87 100 - T 14-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 Tharo_3393 78faf3b23349174be0ac910356de9b63 294 Gene3D G3DSA:3.40.50.150 62 294 1.5E-69 T 14-10-2018 Tharo_3393 78faf3b23349174be0ac910356de9b63 294 Gene3D G3DSA:2.30.140.10 11 60 1.3E-6 T 14-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 Tharo_3393 78faf3b23349174be0ac910356de9b63 294 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 11 294 33.531 T 14-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 Tharo_3393 78faf3b23349174be0ac910356de9b63 294 SUPERFAMILY SSF53335 14 293 1.31E-75 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_3393 78faf3b23349174be0ac910356de9b63 294 Pfam PF01564 Spermine/spermidine synthase domain 66 245 1.5E-44 T 14-10-2018 Tharo_0798 f6bf1586dd29f0936a08741e28062fd5 455 TIGRFAM TIGR01936 nqrA: NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit 7 455 1.8E-179 T 14-10-2018 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 Tharo_0798 f6bf1586dd29f0936a08741e28062fd5 455 Pfam PF11973 NQRA C-terminal domain 269 318 5.6E-18 T 14-10-2018 IPR022615 Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain GO:0016655|GO:0055114 Tharo_0798 f6bf1586dd29f0936a08741e28062fd5 455 Pfam PF05896 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) 6 264 1.4E-103 T 14-10-2018 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 Tharo_0798 f6bf1586dd29f0936a08741e28062fd5 455 Hamap MF_00425 Na(+)-translocating NADH-quinone reductase subunit A [nqrA]. 6 455 44.297 T 14-10-2018 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 Tharo_1872 89bd141d7f1d843c23b0d5f2ad2e650f 523 Pfam PF00501 AMP-binding enzyme 27 422 7.7E-88 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Tharo_1872 89bd141d7f1d843c23b0d5f2ad2e650f 523 SUPERFAMILY SSF56801 23 521 1.44E-142 T 14-10-2018 Tharo_1872 89bd141d7f1d843c23b0d5f2ad2e650f 523 TIGRFAM TIGR02262 benz_CoA_lig: benzoate-CoA ligase family 10 518 2.0E-121 T 14-10-2018 IPR011957 Benzoate-CoA ligase family GO:0005524|GO:0016405 Tharo_1872 89bd141d7f1d843c23b0d5f2ad2e650f 523 Gene3D G3DSA:3.40.50.12780 9 415 3.4E-114 T 14-10-2018 Tharo_1872 89bd141d7f1d843c23b0d5f2ad2e650f 523 Gene3D G3DSA:3.30.300.30 418 523 5.6E-28 T 14-10-2018 Tharo_1872 89bd141d7f1d843c23b0d5f2ad2e650f 523 Pfam PF13193 AMP-binding enzyme C-terminal domain 431 509 1.4E-15 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Tharo_0093 6d7be7ea1a245a177fc165769821a1a8 172 Gene3D G3DSA:3.30.70.920 73 157 4.5E-26 T 14-10-2018 Tharo_0093 6d7be7ea1a245a177fc165769821a1a8 172 Pfam PF13412 Winged helix-turn-helix DNA-binding 19 65 8.7E-18 T 14-10-2018 Tharo_0093 6d7be7ea1a245a177fc165769821a1a8 172 Gene3D G3DSA:1.10.10.10 9 72 1.5E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0093 6d7be7ea1a245a177fc165769821a1a8 172 SUPERFAMILY SSF46785 5 104 2.51E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0093 6d7be7ea1a245a177fc165769821a1a8 172 SUPERFAMILY SSF54909 79 169 7.24E-20 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel Tharo_0093 6d7be7ea1a245a177fc165769821a1a8 172 Pfam PF01037 Lrp/AsnC ligand binding domain 85 159 2.1E-22 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Tharo_0093 6d7be7ea1a245a177fc165769821a1a8 172 SMART SM00344 19 129 1.1E-38 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Tharo_0093 6d7be7ea1a245a177fc165769821a1a8 172 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 46 65 2.1E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Tharo_0093 6d7be7ea1a245a177fc165769821a1a8 172 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 35 2.1E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Tharo_0093 6d7be7ea1a245a177fc165769821a1a8 172 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 46 2.1E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Tharo_0093 6d7be7ea1a245a177fc165769821a1a8 172 ProSitePatterns PS00519 AsnC-type HTH domain signature. 37 63 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site Tharo_2862 10a0a79566d8a6e57c2a62d54f490592 255 Pfam PF01145 SPFH domain / Band 7 family 27 196 1.4E-34 T 14-10-2018 IPR001107 Band 7 domain Tharo_2862 10a0a79566d8a6e57c2a62d54f490592 255 SUPERFAMILY SSF117892 53 186 2.88E-43 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily Tharo_2862 10a0a79566d8a6e57c2a62d54f490592 255 Gene3D G3DSA:3.30.479.30 50 181 6.1E-46 T 14-10-2018 Tharo_2862 10a0a79566d8a6e57c2a62d54f490592 255 SMART SM00244 22 179 1.3E-61 T 14-10-2018 IPR001107 Band 7 domain Tharo_2862 10a0a79566d8a6e57c2a62d54f490592 255 PRINTS PR00721 Stomatin signature 76 97 2.4E-63 T 14-10-2018 IPR001972 Stomatin family GO:0016020 Tharo_2862 10a0a79566d8a6e57c2a62d54f490592 255 PRINTS PR00721 Stomatin signature 29 51 2.4E-63 T 14-10-2018 IPR001972 Stomatin family GO:0016020 Tharo_2862 10a0a79566d8a6e57c2a62d54f490592 255 PRINTS PR00721 Stomatin signature 155 173 2.4E-63 T 14-10-2018 IPR001972 Stomatin family GO:0016020 Tharo_2862 10a0a79566d8a6e57c2a62d54f490592 255 PRINTS PR00721 Stomatin signature 174 195 2.4E-63 T 14-10-2018 IPR001972 Stomatin family GO:0016020 Tharo_2862 10a0a79566d8a6e57c2a62d54f490592 255 PRINTS PR00721 Stomatin signature 111 128 2.4E-63 T 14-10-2018 IPR001972 Stomatin family GO:0016020 Tharo_2862 10a0a79566d8a6e57c2a62d54f490592 255 PRINTS PR00721 Stomatin signature 199 222 2.4E-63 T 14-10-2018 IPR001972 Stomatin family GO:0016020 Tharo_2862 10a0a79566d8a6e57c2a62d54f490592 255 PRINTS PR00721 Stomatin signature 131 154 2.4E-63 T 14-10-2018 IPR001972 Stomatin family GO:0016020 Tharo_2981 07ece4f0280b40ceb612a06d1a0e5896 673 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 416 445 3.1E-54 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_2981 07ece4f0280b40ceb612a06d1a0e5896 673 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 493 520 3.1E-54 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_2981 07ece4f0280b40ceb612a06d1a0e5896 673 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 522 551 3.1E-54 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_2981 07ece4f0280b40ceb612a06d1a0e5896 673 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 570 599 3.1E-54 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Tharo_2981 07ece4f0280b40ceb612a06d1a0e5896 673 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 455 609 4.5E-53 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_2981 07ece4f0280b40ceb612a06d1a0e5896 673 Pfam PF08376 Nitrate and nitrite sensing 58 299 1.3E-11 T 14-10-2018 IPR013587 Nitrate/nitrite sensing protein Tharo_2981 07ece4f0280b40ceb612a06d1a0e5896 673 SUPERFAMILY SSF58104 375 648 5.23E-68 T 14-10-2018 Tharo_2981 07ece4f0280b40ceb612a06d1a0e5896 673 Gene3D G3DSA:1.10.287.950 350 644 1.2E-81 T 14-10-2018 Tharo_2981 07ece4f0280b40ceb612a06d1a0e5896 673 SMART SM00283 395 642 9.8E-88 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_0267 e0cc361d2e7942177dd0eb52bc73d982 197 ProSitePatterns PS00194 Thioredoxin family active site. 65 83 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 Tharo_0267 e0cc361d2e7942177dd0eb52bc73d982 197 Gene3D G3DSA:3.40.30.10 23 195 7.5E-39 T 14-10-2018 Tharo_0267 e0cc361d2e7942177dd0eb52bc73d982 197 Pfam PF08534 Redoxin 37 179 6.5E-13 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 Tharo_0267 e0cc361d2e7942177dd0eb52bc73d982 197 SUPERFAMILY SSF52833 9 190 1.97E-31 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_1183 9ff647e7214dc4716a5904561425e1eb 354 SUPERFAMILY SSF53659 1 354 4.99E-123 T 14-10-2018 Tharo_1183 9ff647e7214dc4716a5904561425e1eb 354 Gene3D G3DSA:3.40.718.10 1 354 2.6E-151 T 14-10-2018 Tharo_1183 9ff647e7214dc4716a5904561425e1eb 354 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 2 349 5.2E-156 T 14-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 Tharo_1183 9ff647e7214dc4716a5904561425e1eb 354 SMART SM01329 2 350 1.6E-208 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 Tharo_1183 9ff647e7214dc4716a5904561425e1eb 354 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 2 350 3.8E-133 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 Tharo_1183 9ff647e7214dc4716a5904561425e1eb 354 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 1 354 52.111 T 14-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 Tharo_1183 9ff647e7214dc4716a5904561425e1eb 354 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 241 260 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 Tharo_1719 e41cb291fde546d19c08f732171a80d1 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.3E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1719 e41cb291fde546d19c08f732171a80d1 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.3E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1719 e41cb291fde546d19c08f732171a80d1 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.3E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1719 e41cb291fde546d19c08f732171a80d1 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.3E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1719 e41cb291fde546d19c08f732171a80d1 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 253 6.6E-85 T 14-10-2018 Tharo_1719 e41cb291fde546d19c08f732171a80d1 265 PIRSF PIRSF000094 1 261 4.0E-114 T 14-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Tharo_1719 e41cb291fde546d19c08f732171a80d1 265 Gene3D G3DSA:3.40.50.720 1 261 7.2E-57 T 14-10-2018 Tharo_1719 e41cb291fde546d19c08f732171a80d1 265 SUPERFAMILY SSF51735 6 253 1.87E-64 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_2488 8213670c5dcdd3009ea3290c65862ba0 129 Pfam PF10861 Protein of Unknown function (DUF2784) 10 117 4.1E-36 T 14-10-2018 IPR021218 Protein of unknown function DUF2784 Tharo_2855 21d97332fcba2faf0aca864c28048dcd 97 Gene3D G3DSA:3.30.2310.20 2 95 1.8E-12 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_2855 21d97332fcba2faf0aca864c28048dcd 97 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 95 3.7E-16 T 14-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Tharo_0648 01a91d732db2cbc0789706c410446d95 250 SUPERFAMILY SSF102705 1 249 2.62E-70 T 14-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily Tharo_0648 01a91d732db2cbc0789706c410446d95 250 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 8 237 2.0E-50 T 14-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 Tharo_0648 01a91d732db2cbc0789706c410446d95 250 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 248 1.1E-55 T 14-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 Tharo_0648 01a91d732db2cbc0789706c410446d95 250 Gene3D G3DSA:3.40.1390.30 97 221 4.9E-72 T 14-10-2018 Tharo_0648 01a91d732db2cbc0789706c410446d95 250 Gene3D G3DSA:3.40.1390.30 16 235 4.9E-72 T 14-10-2018 Tharo_2046 eed27115e192c2ad52f053f31fa52571 347 Pfam PF13476 AAA domain 5 41 3.6E-7 T 14-10-2018 IPR038729 Rad50/SbcC-type AAA domain Tharo_2046 eed27115e192c2ad52f053f31fa52571 347 Gene3D G3DSA:3.40.50.300 1 295 7.1E-22 T 14-10-2018 Tharo_2046 eed27115e192c2ad52f053f31fa52571 347 SMART SM00382 21 312 0.0078 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2046 eed27115e192c2ad52f053f31fa52571 347 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 157 284 1.8E-16 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Tharo_2046 eed27115e192c2ad52f053f31fa52571 347 SUPERFAMILY SSF52540 1 288 1.75E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2588 9b85486b0876665c2b13ece3219b02a3 414 Pfam PF02754 Cysteine-rich domain 308 390 4.5E-9 T 14-10-2018 IPR004017 Cysteine-rich domain Tharo_2588 9b85486b0876665c2b13ece3219b02a3 414 Pfam PF02754 Cysteine-rich domain 171 255 2.4E-11 T 14-10-2018 IPR004017 Cysteine-rich domain Tharo_2588 9b85486b0876665c2b13ece3219b02a3 414 Pfam PF12838 4Fe-4S dicluster domain 24 89 4.4E-13 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_2588 9b85486b0876665c2b13ece3219b02a3 414 SUPERFAMILY SSF54862 21 116 6.28E-20 T 14-10-2018 Tharo_2588 9b85486b0876665c2b13ece3219b02a3 414 PIRSF PIRSF000139 7 412 1.8E-110 T 14-10-2018 Tharo_2588 9b85486b0876665c2b13ece3219b02a3 414 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_2588 9b85486b0876665c2b13ece3219b02a3 414 Gene3D G3DSA:1.10.1060.10 4 104 1.2E-9 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Tharo_0457 118088a3fd5c50584d533f49a7aa4ab8 307 Gene3D G3DSA:3.40.50.720 1 289 4.1E-69 T 14-10-2018 Tharo_0457 118088a3fd5c50584d533f49a7aa4ab8 307 SUPERFAMILY SSF51735 2 285 5.7E-34 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1301 6dc718cfbad601581d938d9853c0a036 576 Gene3D G3DSA:3.40.50.970 188 384 2.3E-57 T 14-10-2018 Tharo_1301 6dc718cfbad601581d938d9853c0a036 576 SUPERFAMILY SSF52518 202 455 9.16E-56 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_1301 6dc718cfbad601581d938d9853c0a036 576 Gene3D G3DSA:3.40.920.10 2 183 1.4E-22 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Tharo_1301 6dc718cfbad601581d938d9853c0a036 576 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 177 2.4E-25 T 14-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 Tharo_1301 6dc718cfbad601581d938d9853c0a036 576 Gene3D G3DSA:3.40.50.920 465 574 1.8E-19 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Tharo_1301 6dc718cfbad601581d938d9853c0a036 576 SUPERFAMILY SSF52922 472 572 1.15E-16 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Tharo_1301 6dc718cfbad601581d938d9853c0a036 576 SUPERFAMILY SSF53323 6 223 1.96E-27 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Tharo_1301 6dc718cfbad601581d938d9853c0a036 576 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 213 445 6.3E-51 T 14-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 Tharo_1301 6dc718cfbad601581d938d9853c0a036 576 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 6 571 1.1E-168 T 14-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 Tharo_0233 c0325ce28f31a7112626dfc619079740 818 Gene3D G3DSA:3.40.50.300 500 686 1.0E-32 T 14-10-2018 Tharo_0233 c0325ce28f31a7112626dfc619079740 818 Pfam PF00271 Helicase conserved C-terminal domain 563 658 2.0E-9 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_0233 c0325ce28f31a7112626dfc619079740 818 Pfam PF13091 PLD-like domain 142 277 1.2E-9 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 Tharo_0233 c0325ce28f31a7112626dfc619079740 818 Gene3D G3DSA:3.30.870.10 132 299 6.9E-22 T 14-10-2018 Tharo_0233 c0325ce28f31a7112626dfc619079740 818 Pfam PF04851 Type III restriction enzyme, res subunit 322 477 8.8E-27 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 Tharo_0233 c0325ce28f31a7112626dfc619079740 818 SMART SM00487 320 500 9.9E-10 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Tharo_0233 c0325ce28f31a7112626dfc619079740 818 Gene3D G3DSA:3.40.50.300 312 490 2.2E-39 T 14-10-2018 Tharo_0233 c0325ce28f31a7112626dfc619079740 818 SUPERFAMILY SSF52540 374 674 1.87E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0233 c0325ce28f31a7112626dfc619079740 818 SUPERFAMILY SSF56024 130 279 1.88E-6 T 14-10-2018 Tharo_0233 c0325ce28f31a7112626dfc619079740 818 SMART SM00490 579 660 5.1E-8 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_2052 7207505389523811a34858720e7a5280 268 Gene3D G3DSA:3.30.1330.30 8 105 6.7E-16 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like Tharo_2052 7207505389523811a34858720e7a5280 268 SUPERFAMILY SSF55315 3 104 4.71E-17 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like Tharo_2052 7207505389523811a34858720e7a5280 268 SMART SM00967 32 107 6.0E-4 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 Tharo_2052 7207505389523811a34858720e7a5280 268 Pfam PF00588 SpoU rRNA Methylase family 116 253 5.0E-34 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Tharo_2052 7207505389523811a34858720e7a5280 268 SUPERFAMILY SSF75217 114 260 2.62E-42 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases Tharo_2052 7207505389523811a34858720e7a5280 268 Gene3D G3DSA:3.40.1280.10 112 266 1.3E-45 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Tharo_0604 43a39e0e9db20323ac33db25fde48615 279 SMART SM00116 129 177 2.4 T 14-10-2018 IPR000644 CBS domain Tharo_0604 43a39e0e9db20323ac33db25fde48615 279 SMART SM00116 68 117 5.7 T 14-10-2018 IPR000644 CBS domain Tharo_0604 43a39e0e9db20323ac33db25fde48615 279 SUPERFAMILY SSF54631 48 186 2.65E-31 T 14-10-2018 Tharo_0604 43a39e0e9db20323ac33db25fde48615 279 Gene3D G3DSA:3.10.580.10 39 185 3.5E-51 T 14-10-2018 Tharo_0604 43a39e0e9db20323ac33db25fde48615 279 Pfam PF00571 CBS domain 123 177 4.6E-6 T 14-10-2018 IPR000644 CBS domain Tharo_0604 43a39e0e9db20323ac33db25fde48615 279 Pfam PF00571 CBS domain 59 117 1.1E-5 T 14-10-2018 IPR000644 CBS domain Tharo_0604 43a39e0e9db20323ac33db25fde48615 279 SUPERFAMILY SSF56176 193 274 1.34E-22 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Tharo_0604 43a39e0e9db20323ac33db25fde48615 279 SMART SM01091 194 272 7.7E-29 T 14-10-2018 IPR005170 Transporter-associated domain Tharo_0604 43a39e0e9db20323ac33db25fde48615 279 Gene3D G3DSA:3.30.465.10 186 271 3.4E-31 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Tharo_0604 43a39e0e9db20323ac33db25fde48615 279 Pfam PF03471 Transporter associated domain 198 271 1.3E-22 T 14-10-2018 IPR005170 Transporter-associated domain Tharo_1865 9c5fa817840457ba1eba282b5715fc35 479 Pfam PF11870 Domain of unknown function (DUF3390) 389 475 2.6E-26 T 14-10-2018 IPR024569 4Fe-4S binding protein, C-terminal Tharo_1865 9c5fa817840457ba1eba282b5715fc35 479 SUPERFAMILY SSF100950 69 299 2.01E-43 T 14-10-2018 IPR037171 NagB/RpiA transferase-like Tharo_1865 9c5fa817840457ba1eba282b5715fc35 479 SUPERFAMILY SSF46548 271 395 1.12E-16 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Tharo_1865 9c5fa817840457ba1eba282b5715fc35 479 Pfam PF02589 LUD domain 74 298 1.1E-53 T 14-10-2018 IPR003741 LUD domain Tharo_1865 9c5fa817840457ba1eba282b5715fc35 479 Pfam PF13183 4Fe-4S dicluster domain 315 381 8.5E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_1865 9c5fa817840457ba1eba282b5715fc35 479 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 23 444 3.1E-145 T 14-10-2018 IPR004452 4Fe-4S binding protein GO:0019516 Tharo_1865 9c5fa817840457ba1eba282b5715fc35 479 Gene3D G3DSA:3.40.50.10420 135 298 4.4E-16 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily Tharo_1865 9c5fa817840457ba1eba282b5715fc35 479 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 317 328 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_3140 d63cc0363f3bd1d602fb3adb3b263519 839 TIGRFAM TIGR03607 TIGR03607: patatin-related protein 5 789 1.3E-185 T 14-10-2018 IPR019894 Patatin-related protein Tharo_3140 d63cc0363f3bd1d602fb3adb3b263519 839 Pfam PF01734 Patatin-like phospholipase 77 358 5.5E-15 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 Tharo_3140 d63cc0363f3bd1d602fb3adb3b263519 839 Pfam PF11856 Protein of unknown function (DUF3376) 704 788 1.2E-14 T 14-10-2018 IPR024282 Domain of unknown function DUF3376 Tharo_3140 d63cc0363f3bd1d602fb3adb3b263519 839 SUPERFAMILY SSF52151 5 370 1.99E-20 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase Tharo_0627 16ede92cd2784d4be04e265d7d3fe055 207 Gene3D G3DSA:1.10.10.640 69 193 6.6E-61 T 14-10-2018 Tharo_0627 16ede92cd2784d4be04e265d7d3fe055 207 Gene3D G3DSA:3.10.450.50 32 168 6.6E-61 T 14-10-2018 Tharo_0627 16ede92cd2784d4be04e265d7d3fe055 207 PIRSF PIRSF004649 1 207 1.1E-59 T 14-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC Tharo_0627 16ede92cd2784d4be04e265d7d3fe055 207 Pfam PF05494 MlaC protein 32 194 3.4E-59 T 14-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC Tharo_2192 99429d548062405bb040a335891049ee 63 SUPERFAMILY SSF158997 1 55 2.09E-21 T 14-10-2018 Tharo_2192 99429d548062405bb040a335891049ee 63 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 1 54 28.218 T 14-10-2018 IPR038053 Uncharacterised protein family UPF0434 Tharo_2192 99429d548062405bb040a335891049ee 63 Pfam PF03966 Trm112p-like protein 2 40 1.0E-11 T 14-10-2018 IPR005651 Trm112-like Tharo_2192 99429d548062405bb040a335891049ee 63 Gene3D G3DSA:2.20.25.10 8 63 2.8E-27 T 14-10-2018 Tharo_3435 c2334aee3b17c366472e15b6b4c3aa18 137 SUPERFAMILY SSF56349 16 121 7.18E-6 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Tharo_3435 c2334aee3b17c366472e15b6b4c3aa18 137 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 17 98 2.7E-25 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 Tharo_3435 c2334aee3b17c366472e15b6b4c3aa18 137 Gene3D G3DSA:1.10.150.130 13 100 9.7E-33 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Tharo_0835 5722628f0b7bdcf1086c7c8faf462b1f 497 Gene3D G3DSA:1.10.246.130 179 298 3.2E-40 T 14-10-2018 Tharo_0835 5722628f0b7bdcf1086c7c8faf462b1f 497 Pfam PF01019 Gamma-glutamyltranspeptidase 3 480 1.1E-130 T 14-10-2018 Tharo_0835 5722628f0b7bdcf1086c7c8faf462b1f 497 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 385 402 1.3E-58 T 14-10-2018 Tharo_0835 5722628f0b7bdcf1086c7c8faf462b1f 497 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 163 179 1.3E-58 T 14-10-2018 Tharo_0835 5722628f0b7bdcf1086c7c8faf462b1f 497 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 38 56 1.3E-58 T 14-10-2018 Tharo_0835 5722628f0b7bdcf1086c7c8faf462b1f 497 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 361 376 1.3E-58 T 14-10-2018 Tharo_0835 5722628f0b7bdcf1086c7c8faf462b1f 497 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 330 348 1.3E-58 T 14-10-2018 Tharo_0835 5722628f0b7bdcf1086c7c8faf462b1f 497 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 56 75 1.3E-58 T 14-10-2018 Tharo_0835 5722628f0b7bdcf1086c7c8faf462b1f 497 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 306 324 1.3E-58 T 14-10-2018 Tharo_0835 5722628f0b7bdcf1086c7c8faf462b1f 497 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 193 212 1.3E-58 T 14-10-2018 Tharo_0835 5722628f0b7bdcf1086c7c8faf462b1f 497 Gene3D G3DSA:3.60.20.40 306 485 1.1E-52 T 14-10-2018 Tharo_0835 5722628f0b7bdcf1086c7c8faf462b1f 497 SUPERFAMILY SSF56235 2 482 1.83E-133 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Tharo_0835 5722628f0b7bdcf1086c7c8faf462b1f 497 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 2 477 2.1E-114 T 14-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 Tharo_0775 06960282a4b1e7c48943f5c5be5555b0 299 Pfam PF00156 Phosphoribosyl transferase domain 161 286 1.6E-12 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Tharo_0775 06960282a4b1e7c48943f5c5be5555b0 299 SUPERFAMILY SSF53271 18 155 1.91E-21 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Tharo_0775 06960282a4b1e7c48943f5c5be5555b0 299 SMART SM01400 6 118 8.9E-20 T 14-10-2018 Tharo_0775 06960282a4b1e7c48943f5c5be5555b0 299 Gene3D G3DSA:3.40.50.2020 19 146 2.7E-61 T 14-10-2018 Tharo_0775 06960282a4b1e7c48943f5c5be5555b0 299 Gene3D G3DSA:3.40.50.2020 147 276 2.7E-61 T 14-10-2018 Tharo_0775 06960282a4b1e7c48943f5c5be5555b0 299 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 18 296 2.2E-53 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Tharo_0775 06960282a4b1e7c48943f5c5be5555b0 299 SUPERFAMILY SSF53271 165 295 1.97E-28 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Tharo_0775 06960282a4b1e7c48943f5c5be5555b0 299 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 21 116 8.9E-10 T 14-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Tharo_2529 2f3f48b57076878990af95c81ffb9190 121 Pfam PF00072 Response regulator receiver domain 4 114 1.2E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2529 2f3f48b57076878990af95c81ffb9190 121 SUPERFAMILY SSF52172 1 120 7.12E-31 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_2529 2f3f48b57076878990af95c81ffb9190 121 Gene3D G3DSA:3.40.50.12740 1 121 1.3E-30 T 14-10-2018 Tharo_2529 2f3f48b57076878990af95c81ffb9190 121 SMART SM00448 2 116 1.4E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_0477 f9cc34400cea052a6b86cfcd3eec0c5d 196 Gene3D G3DSA:3.90.1570.10 6 195 1.8E-36 T 14-10-2018 Tharo_0477 f9cc34400cea052a6b86cfcd3eec0c5d 196 SUPERFAMILY SSF52980 8 186 2.09E-37 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Tharo_0477 f9cc34400cea052a6b86cfcd3eec0c5d 196 Pfam PF05685 Putative restriction endonuclease 14 186 2.0E-33 T 14-10-2018 IPR008538 Domain of unknown function DUF820 Tharo_1524 82fba60ffe3661abc8cd5dc28ad15f6f 385 Pfam PF00925 GTP cyclohydrolase II 167 332 4.5E-56 T 14-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Tharo_1524 82fba60ffe3661abc8cd5dc28ad15f6f 385 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 163 360 38.202 T 14-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Tharo_1524 82fba60ffe3661abc8cd5dc28ad15f6f 385 SUPERFAMILY SSF142695 166 335 4.05E-50 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Tharo_1524 82fba60ffe3661abc8cd5dc28ad15f6f 385 Gene3D G3DSA:3.40.50.10990 163 336 5.6E-60 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Tharo_2091 8d6370d4a6d619c559aa9e98a9224eeb 246 Gene3D G3DSA:3.40.1280.10 5 170 3.4E-58 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Tharo_2091 8d6370d4a6d619c559aa9e98a9224eeb 246 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 8 240 2.0E-59 T 14-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 Tharo_2091 8d6370d4a6d619c559aa9e98a9224eeb 246 Gene3D G3DSA:1.10.8.590 179 240 1.1E-24 T 14-10-2018 Tharo_2091 8d6370d4a6d619c559aa9e98a9224eeb 246 SUPERFAMILY SSF75217 9 166 1.24E-31 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases Tharo_2091 8d6370d4a6d619c559aa9e98a9224eeb 246 PIRSF PIRSF004808 5 245 3.4E-68 T 14-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 Tharo_2091 8d6370d4a6d619c559aa9e98a9224eeb 246 Pfam PF00588 SpoU rRNA Methylase family 10 159 2.2E-30 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Tharo_3229 bddb647f9bf7cb235cb6ddb043e64c69 395 Pfam PF13191 AAA ATPase domain 19 204 2.4E-16 T 14-10-2018 Tharo_3229 bddb647f9bf7cb235cb6ddb043e64c69 395 SUPERFAMILY SSF52540 6 283 2.7E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3229 bddb647f9bf7cb235cb6ddb043e64c69 395 Gene3D G3DSA:3.40.50.300 8 222 2.1E-11 T 14-10-2018 Tharo_1876 0a8d2e8f7e0f44aa9e76550d3ccb9cd5 217 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 49 60 9.6E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1876 0a8d2e8f7e0f44aa9e76550d3ccb9cd5 217 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 142 9.6E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1876 0a8d2e8f7e0f44aa9e76550d3ccb9cd5 217 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 103 111 9.6E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1876 0a8d2e8f7e0f44aa9e76550d3ccb9cd5 217 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 110 138 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Tharo_1876 0a8d2e8f7e0f44aa9e76550d3ccb9cd5 217 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 197 1.3E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1876 0a8d2e8f7e0f44aa9e76550d3ccb9cd5 217 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 97 113 1.3E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1876 0a8d2e8f7e0f44aa9e76550d3ccb9cd5 217 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 142 1.3E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1876 0a8d2e8f7e0f44aa9e76550d3ccb9cd5 217 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 49 60 1.3E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1876 0a8d2e8f7e0f44aa9e76550d3ccb9cd5 217 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 161 1.3E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_1876 0a8d2e8f7e0f44aa9e76550d3ccb9cd5 217 SUPERFAMILY SSF51735 1 216 2.43E-63 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1876 0a8d2e8f7e0f44aa9e76550d3ccb9cd5 217 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 2 214 1.4E-50 T 14-10-2018 Tharo_1876 0a8d2e8f7e0f44aa9e76550d3ccb9cd5 217 Gene3D G3DSA:3.40.50.720 1 216 5.0E-66 T 14-10-2018 Tharo_2734 167e7b5931bee87ac0475ac16cbfd739 232 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 14-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2734 167e7b5931bee87ac0475ac16cbfd739 232 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 43.473 T 14-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Tharo_2734 167e7b5931bee87ac0475ac16cbfd739 232 Pfam PF00687 Ribosomal protein L1p/L10e family 31 219 4.9E-52 T 14-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein Tharo_2734 167e7b5931bee87ac0475ac16cbfd739 232 SUPERFAMILY SSF56808 6 225 2.35E-82 T 14-10-2018 IPR023674 Ribosomal protein L1-like Tharo_2734 167e7b5931bee87ac0475ac16cbfd739 232 PIRSF PIRSF002155 1 227 3.7E-77 T 14-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2734 167e7b5931bee87ac0475ac16cbfd739 232 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 1.6E-104 T 14-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Tharo_2734 167e7b5931bee87ac0475ac16cbfd739 232 Gene3D G3DSA:3.30.190.20 25 222 5.1E-78 T 14-10-2018 Tharo_2734 167e7b5931bee87ac0475ac16cbfd739 232 Gene3D G3DSA:3.40.50.790 68 159 5.1E-78 T 14-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich Tharo_0902 e3e1f69373d3fc4dca3eb2ed6f3b7fb9 290 TIGRFAM TIGR02098 MJ0042_CXXC: MJ0042 family finger-like domain 4 38 4.5E-12 T 14-10-2018 IPR011723 Zinc finger/thioredoxin putative Tharo_0902 e3e1f69373d3fc4dca3eb2ed6f3b7fb9 290 Pfam PF11906 Protein of unknown function (DUF3426) 143 287 2.2E-43 T 14-10-2018 IPR021834 Protein of unknown function DUF3426 Tharo_0902 e3e1f69373d3fc4dca3eb2ed6f3b7fb9 290 Pfam PF13719 zinc-ribbon domain 4 38 2.9E-11 T 14-10-2018 IPR011723 Zinc finger/thioredoxin putative Tharo_1777 22675ece55cd49712e2eecba959a815e 487 Pfam PF13638 PIN domain 33 178 1.2E-39 T 14-10-2018 IPR002716 PIN domain Tharo_1777 22675ece55cd49712e2eecba959a815e 487 SMART SM00670 31 166 4.0E-7 T 14-10-2018 IPR002716 PIN domain Tharo_1777 22675ece55cd49712e2eecba959a815e 487 SUPERFAMILY SSF52540 273 467 2.81E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1777 22675ece55cd49712e2eecba959a815e 487 SUPERFAMILY SSF88723 31 183 1.51E-9 T 14-10-2018 IPR029060 PIN-like domain superfamily Tharo_1777 22675ece55cd49712e2eecba959a815e 487 Gene3D G3DSA:3.40.50.300 272 487 1.0E-65 T 14-10-2018 Tharo_1777 22675ece55cd49712e2eecba959a815e 487 Gene3D G3DSA:3.40.50.1010 30 181 6.9E-25 T 14-10-2018 Tharo_1777 22675ece55cd49712e2eecba959a815e 487 Pfam PF02562 PhoH-like protein 274 481 3.3E-53 T 14-10-2018 IPR003714 PhoH-like protein GO:0005524 Tharo_3094 ca3ad8aca492e56fc1b6c3ac33e398ba 163 Pfam PF04355 SmpA / OmlA family 86 154 1.3E-6 T 14-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 Tharo_3094 ca3ad8aca492e56fc1b6c3ac33e398ba 163 Gene3D G3DSA:3.30.1450.10 81 160 3.6E-6 T 14-10-2018 IPR037873 BamE-like Tharo_3118 777f8ee0c4857e15b56b28f63ad0236d 133 SUPERFAMILY SSF88659 47 97 6.28E-11 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Tharo_3118 777f8ee0c4857e15b56b28f63ad0236d 133 Pfam PF08281 Sigma-70, region 4 59 90 9.6E-10 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Tharo_3118 777f8ee0c4857e15b56b28f63ad0236d 133 Gene3D G3DSA:1.10.10.10 46 101 6.1E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2396 f12db2162a98a4e9bc9e2922a6ef363d 240 Pfam PF00156 Phosphoribosyl transferase domain 145 237 7.2E-8 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Tharo_2396 f12db2162a98a4e9bc9e2922a6ef363d 240 Gene3D G3DSA:3.40.50.2020 75 239 7.7E-17 T 14-10-2018 Tharo_2396 f12db2162a98a4e9bc9e2922a6ef363d 240 SUPERFAMILY SSF53271 64 237 1.57E-28 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Tharo_1492 c0cea96f061f06975a253fb06203e30a 86 Gene3D G3DSA:3.10.20.30 5 86 1.3E-24 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Tharo_1492 c0cea96f061f06975a253fb06203e30a 86 Pfam PF02597 ThiS family 7 86 7.6E-20 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 Tharo_1492 c0cea96f061f06975a253fb06203e30a 86 SUPERFAMILY SSF54285 5 86 2.06E-21 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp Tharo_1492 c0cea96f061f06975a253fb06203e30a 86 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 5 86 2.7E-24 T 14-10-2018 Tharo_1385 1ad9d9309564ec2904a075e3b6860376 166 Pfam PF13673 Acetyltransferase (GNAT) domain 89 152 1.3E-8 T 14-10-2018 IPR000182 GNAT domain Tharo_1385 1ad9d9309564ec2904a075e3b6860376 166 SUPERFAMILY SSF55729 25 149 3.6E-13 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Tharo_1385 1ad9d9309564ec2904a075e3b6860376 166 Gene3D G3DSA:3.40.630.30 2 159 1.5E-43 T 14-10-2018 Tharo_1079 16a268683a9af49e2456aee0063ccbe2 192 Pfam PF09335 SNARE associated Golgi protein 37 157 1.0E-13 T 14-10-2018 IPR032816 SNARE associated Golgi protein Tharo_0635 e31c7409e02b08ea3a2a87550be7966b 444 Pfam PF00815 Histidinol dehydrogenase 38 442 8.4E-166 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Tharo_0635 e31c7409e02b08ea3a2a87550be7966b 444 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 244 276 - T 14-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 Tharo_0635 e31c7409e02b08ea3a2a87550be7966b 444 SUPERFAMILY SSF53720 39 442 6.28E-87 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Tharo_0635 e31c7409e02b08ea3a2a87550be7966b 444 Gene3D G3DSA:3.40.50.1980 248 364 7.3E-130 T 14-10-2018 Tharo_0635 e31c7409e02b08ea3a2a87550be7966b 444 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 47 441 3.8E-158 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Tharo_0635 e31c7409e02b08ea3a2a87550be7966b 444 PIRSF PIRSF000099 12 444 1.1E-157 T 14-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Tharo_0635 e31c7409e02b08ea3a2a87550be7966b 444 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 16 442 40.508 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Tharo_0635 e31c7409e02b08ea3a2a87550be7966b 444 Gene3D G3DSA:3.40.50.1980 44 246 7.3E-130 T 14-10-2018 Tharo_0635 e31c7409e02b08ea3a2a87550be7966b 444 PRINTS PR00083 Histidinol dehydrogenase signature 244 265 4.1E-82 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Tharo_0635 e31c7409e02b08ea3a2a87550be7966b 444 PRINTS PR00083 Histidinol dehydrogenase signature 47 71 4.1E-82 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Tharo_0635 e31c7409e02b08ea3a2a87550be7966b 444 PRINTS PR00083 Histidinol dehydrogenase signature 151 177 4.1E-82 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Tharo_0635 e31c7409e02b08ea3a2a87550be7966b 444 PRINTS PR00083 Histidinol dehydrogenase signature 185 211 4.1E-82 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Tharo_0635 e31c7409e02b08ea3a2a87550be7966b 444 PRINTS PR00083 Histidinol dehydrogenase signature 335 360 4.1E-82 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Tharo_0635 e31c7409e02b08ea3a2a87550be7966b 444 PRINTS PR00083 Histidinol dehydrogenase signature 266 285 4.1E-82 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Tharo_0635 e31c7409e02b08ea3a2a87550be7966b 444 PRINTS PR00083 Histidinol dehydrogenase signature 215 240 4.1E-82 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Tharo_0635 e31c7409e02b08ea3a2a87550be7966b 444 PRINTS PR00083 Histidinol dehydrogenase signature 376 394 4.1E-82 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Tharo_1346 2f869e1625458eab5425c6f8d2620160 400 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 5.4E-22 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Tharo_1346 2f869e1625458eab5425c6f8d2620160 400 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 67 86 5.4E-22 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Tharo_1346 2f869e1625458eab5425c6f8d2620160 400 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 145 166 5.4E-22 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Tharo_1346 2f869e1625458eab5425c6f8d2620160 400 Gene3D G3DSA:3.40.50.620 1 227 5.9E-75 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_1346 2f869e1625458eab5425c6f8d2620160 400 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 4 173 7.9E-59 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Tharo_1346 2f869e1625458eab5425c6f8d2620160 400 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 21 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_1346 2f869e1625458eab5425c6f8d2620160 400 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 3 398 35.03 T 14-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 Tharo_1346 2f869e1625458eab5425c6f8d2620160 400 Gene3D G3DSA:1.10.240.10 260 365 1.1E-35 T 14-10-2018 Tharo_1346 2f869e1625458eab5425c6f8d2620160 400 SUPERFAMILY SSF52374 5 397 1.77E-85 T 14-10-2018 Tharo_1346 2f869e1625458eab5425c6f8d2620160 400 Pfam PF00579 tRNA synthetases class I (W and Y) 5 170 1.5E-49 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_1346 2f869e1625458eab5425c6f8d2620160 400 Pfam PF00579 tRNA synthetases class I (W and Y) 243 348 1.2E-9 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Tharo_2443 84881e8309555f199109af439ea3f011 336 Gene3D G3DSA:1.10.287.950 3 237 9.5E-46 T 14-10-2018 Tharo_2443 84881e8309555f199109af439ea3f011 336 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 87 216 8.6E-34 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_2443 84881e8309555f199109af439ea3f011 336 SUPERFAMILY SSF58104 23 232 1.11E-48 T 14-10-2018 Tharo_2443 84881e8309555f199109af439ea3f011 336 Pfam PF13682 Chemoreceptor zinc-binding domain 244 297 2.9E-12 T 14-10-2018 IPR025991 Chemoreceptor zinc-binding domain Tharo_2443 84881e8309555f199109af439ea3f011 336 SMART SM00283 3 248 1.1E-21 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_2044 3bc502d30bf3e6972130eb78365b4fc6 530 SUPERFAMILY SSF53335 85 527 1.84E-29 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_2634 053e6c8b3493023510738713b0cc8f00 1311 SMART SM01211 1055 1310 2.9E-144 T 14-10-2018 Tharo_2634 053e6c8b3493023510738713b0cc8f00 1311 Gene3D G3DSA:3.30.1330.10 213 414 2.2E-43 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Tharo_2634 053e6c8b3493023510738713b0cc8f00 1311 SUPERFAMILY SSF109736 154 219 5.23E-22 T 14-10-2018 Tharo_2634 053e6c8b3493023510738713b0cc8f00 1311 SUPERFAMILY SSF52317 1051 1310 1.6E-91 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Tharo_2634 053e6c8b3493023510738713b0cc8f00 1311 Gene3D G3DSA:3.30.1330.10 612 801 1.1E-22 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Tharo_2634 053e6c8b3493023510738713b0cc8f00 1311 Pfam PF02769 AIR synthase related protein, C-terminal domain 426 583 1.9E-27 T 14-10-2018 IPR010918 PurM-like, C-terminal domain Tharo_2634 053e6c8b3493023510738713b0cc8f00 1311 Pfam PF02769 AIR synthase related protein, C-terminal domain 829 982 7.6E-11 T 14-10-2018 IPR010918 PurM-like, C-terminal domain Tharo_2634 053e6c8b3493023510738713b0cc8f00 1311 Gene3D G3DSA:3.90.650.10 810 996 1.6E-29 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Tharo_2634 053e6c8b3493023510738713b0cc8f00 1311 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 4 1311 20.922 T 14-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Tharo_2634 053e6c8b3493023510738713b0cc8f00 1311 Gene3D G3DSA:1.10.8.750 152 212 6.8E-29 T 14-10-2018 Tharo_2634 053e6c8b3493023510738713b0cc8f00 1311 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1055 1310 9.9E-103 T 14-10-2018 Tharo_2634 053e6c8b3493023510738713b0cc8f00 1311 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 7 1310 0.0 T 14-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Tharo_2634 053e6c8b3493023510738713b0cc8f00 1311 Gene3D G3DSA:3.40.50.880 997 1311 1.5E-128 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Tharo_2634 053e6c8b3493023510738713b0cc8f00 1311 SUPERFAMILY SSF55326 614 809 1.02E-64 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Tharo_2634 053e6c8b3493023510738713b0cc8f00 1311 SUPERFAMILY SSF56042 817 1048 1.32E-46 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Tharo_2634 053e6c8b3493023510738713b0cc8f00 1311 Gene3D G3DSA:3.90.650.10 415 600 1.3E-55 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Tharo_2634 053e6c8b3493023510738713b0cc8f00 1311 SUPERFAMILY SSF82697 5 151 3.98E-41 T 14-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Tharo_2634 053e6c8b3493023510738713b0cc8f00 1311 SUPERFAMILY SSF55326 220 418 4.53E-63 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Tharo_2634 053e6c8b3493023510738713b0cc8f00 1311 SUPERFAMILY SSF56042 426 649 4.19E-52 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Tharo_0888 fa7a206fe5717f939d805889793048fd 1092 SMART SM00490 950 1030 1.3E-18 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_0888 fa7a206fe5717f939d805889793048fd 1092 Pfam PF00271 Helicase conserved C-terminal domain 921 1030 8.4E-15 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_0888 fa7a206fe5717f939d805889793048fd 1092 Gene3D G3DSA:1.20.120.850 857 1079 3.0E-77 T 14-10-2018 Tharo_0888 fa7a206fe5717f939d805889793048fd 1092 Pfam PF04434 SWIM zinc finger 66 89 5.2E-5 T 14-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 Tharo_0888 fa7a206fe5717f939d805889793048fd 1092 SUPERFAMILY SSF52540 837 1084 6.27E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0888 fa7a206fe5717f939d805889793048fd 1092 Pfam PF00176 SNF2 family N-terminal domain 644 907 1.0E-55 T 14-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 Tharo_0888 fa7a206fe5717f939d805889793048fd 1092 Gene3D G3DSA:3.40.50.300 842 1044 3.0E-77 T 14-10-2018 Tharo_0888 fa7a206fe5717f939d805889793048fd 1092 SUPERFAMILY SSF52540 613 835 3.12E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0888 fa7a206fe5717f939d805889793048fd 1092 SMART SM00487 620 804 3.5E-29 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Tharo_0888 fa7a206fe5717f939d805889793048fd 1092 Gene3D G3DSA:3.40.50.10810 625 836 6.4E-63 T 14-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily Tharo_3209 27ce4f1339057032cc2df5ef4b9ac714 316 Pfam PF01903 CbiX 139 242 4.8E-16 T 14-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 Tharo_3209 27ce4f1339057032cc2df5ef4b9ac714 316 Pfam PF01903 CbiX 11 113 1.2E-18 T 14-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 Tharo_3209 27ce4f1339057032cc2df5ef4b9ac714 316 Gene3D G3DSA:3.40.50.1400 3 124 1.6E-23 T 14-10-2018 Tharo_3209 27ce4f1339057032cc2df5ef4b9ac714 316 Gene3D G3DSA:3.40.50.1400 129 250 1.9E-17 T 14-10-2018 Tharo_3209 27ce4f1339057032cc2df5ef4b9ac714 316 SUPERFAMILY SSF53800 6 249 9.81E-29 T 14-10-2018 Tharo_1820 7b3fb83f64a47a96915735852eac96ef 407 Pfam PF02515 CoA-transferase family III 5 383 6.1E-134 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 Tharo_1820 7b3fb83f64a47a96915735852eac96ef 407 Gene3D G3DSA:3.40.50.10540 5 401 1.2E-145 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily Tharo_1820 7b3fb83f64a47a96915735852eac96ef 407 SUPERFAMILY SSF89796 3 407 2.88E-149 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily Tharo_1820 7b3fb83f64a47a96915735852eac96ef 407 Gene3D G3DSA:3.30.1540.10 243 334 1.2E-145 T 14-10-2018 Tharo_3376 b7aa8d1f5b34a17913a9132752ab5e67 439 Pfam PF01794 Ferric reductase like transmembrane component 43 169 9.1E-22 T 14-10-2018 IPR013130 Ferric reductase transmembrane component-like domain Tharo_3376 b7aa8d1f5b34a17913a9132752ab5e67 439 Gene3D G3DSA:3.40.50.80 310 439 1.6E-22 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_3376 b7aa8d1f5b34a17913a9132752ab5e67 439 Pfam PF08022 FAD-binding domain 243 305 1.6E-7 T 14-10-2018 IPR013112 FAD-binding 8 GO:0016491|GO:0055114 Tharo_3376 b7aa8d1f5b34a17913a9132752ab5e67 439 SUPERFAMILY SSF63380 216 308 1.34E-17 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Tharo_3376 b7aa8d1f5b34a17913a9132752ab5e67 439 SUPERFAMILY SSF52343 298 426 3.27E-22 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_3376 b7aa8d1f5b34a17913a9132752ab5e67 439 Gene3D G3DSA:2.40.30.10 208 305 6.4E-14 T 14-10-2018 Tharo_2843 b2e248be6a8de927e70f35db3774f147 483 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 40 479 5.3E-95 T 14-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 Tharo_2843 b2e248be6a8de927e70f35db3774f147 483 Gene3D G3DSA:2.20.200.10 126 368 4.6E-114 T 14-10-2018 Tharo_2843 b2e248be6a8de927e70f35db3774f147 483 Pfam PF02321 Outer membrane efflux protein 89 270 5.5E-25 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Tharo_2843 b2e248be6a8de927e70f35db3774f147 483 Pfam PF02321 Outer membrane efflux protein 298 477 7.3E-18 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Tharo_2843 b2e248be6a8de927e70f35db3774f147 483 SUPERFAMILY SSF56954 30 481 2.62E-96 T 14-10-2018 Tharo_2843 b2e248be6a8de927e70f35db3774f147 483 Gene3D G3DSA:1.20.1600.10 79 480 4.6E-114 T 14-10-2018 Tharo_2551 7f4a7410366c1c664fb62f6e26b66d57 396 SUPERFAMILY SSF89796 5 395 1.57E-80 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily Tharo_2551 7f4a7410366c1c664fb62f6e26b66d57 396 Pfam PF02515 CoA-transferase family III 5 372 1.7E-70 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 Tharo_2551 7f4a7410366c1c664fb62f6e26b66d57 396 Gene3D G3DSA:3.30.1540.10 230 320 1.6E-79 T 14-10-2018 Tharo_2551 7f4a7410366c1c664fb62f6e26b66d57 396 Gene3D G3DSA:3.40.50.10540 5 339 1.6E-79 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily Tharo_1289 cecd77e9d33640b1d20c4dbdbdd9a960 444 Gene3D G3DSA:3.40.50.12780 1 330 2.8E-140 T 14-10-2018 Tharo_1289 cecd77e9d33640b1d20c4dbdbdd9a960 444 Pfam PF14535 AMP-binding enzyme C-terminal domain 339 437 3.9E-24 T 14-10-2018 IPR028154 AMP-dependent ligase, C-terminal Tharo_1289 cecd77e9d33640b1d20c4dbdbdd9a960 444 Gene3D G3DSA:3.30.300.30 331 439 3.0E-29 T 14-10-2018 Tharo_1289 cecd77e9d33640b1d20c4dbdbdd9a960 444 Pfam PF00501 AMP-binding enzyme 89 294 1.0E-15 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Tharo_1289 cecd77e9d33640b1d20c4dbdbdd9a960 444 SUPERFAMILY SSF56801 28 436 3.27E-68 T 14-10-2018 Tharo_1289 cecd77e9d33640b1d20c4dbdbdd9a960 444 PIRSF PIRSF006444 3 439 1.8E-206 T 14-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 Tharo_1289 cecd77e9d33640b1d20c4dbdbdd9a960 444 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 18 437 1.9E-211 T 14-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 Tharo_1095 9cac50996e1e42993a43ce543b68fad6 441 SUPERFAMILY SSF56059 109 405 5.65E-5 T 14-10-2018 Tharo_2466 a813f8bbd92d53cb804a89209bb87399 685 Gene3D G3DSA:2.20.200.10 126 380 1.1E-103 T 14-10-2018 Tharo_2466 a813f8bbd92d53cb804a89209bb87399 685 Pfam PF02321 Outer membrane efflux protein 89 281 4.5E-23 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Tharo_2466 a813f8bbd92d53cb804a89209bb87399 685 Pfam PF02321 Outer membrane efflux protein 311 471 4.4E-20 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Tharo_2466 a813f8bbd92d53cb804a89209bb87399 685 Gene3D G3DSA:1.20.1600.10 79 491 1.1E-103 T 14-10-2018 Tharo_2466 a813f8bbd92d53cb804a89209bb87399 685 Pfam PF05036 Sporulation related domain 533 611 6.2E-5 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 Tharo_2466 a813f8bbd92d53cb804a89209bb87399 685 SUPERFAMILY SSF56954 12 497 2.62E-90 T 14-10-2018 Tharo_2466 a813f8bbd92d53cb804a89209bb87399 685 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 21 491 9.1E-94 T 14-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 Tharo_2944 807f0988798cec58d6f87f48b3b3344f 682 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 326 4.4E-73 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Tharo_2944 807f0988798cec58d6f87f48b3b3344f 682 SMART SM00878 340 456 1.0E-44 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Tharo_2944 807f0988798cec58d6f87f48b3b3344f 682 Gene3D G3DSA:3.30.470.130 1 462 1.2E-191 T 14-10-2018 Tharo_2944 807f0988798cec58d6f87f48b3b3344f 682 Gene3D G3DSA:2.40.50.100 612 680 3.4E-21 T 14-10-2018 Tharo_2944 807f0988798cec58d6f87f48b3b3344f 682 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.7E-45 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Tharo_2944 807f0988798cec58d6f87f48b3b3344f 682 SUPERFAMILY SSF51246 335 460 3.92E-33 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 Tharo_2944 807f0988798cec58d6f87f48b3b3344f 682 SUPERFAMILY SSF56059 83 352 8.66E-66 T 14-10-2018 Tharo_2944 807f0988798cec58d6f87f48b3b3344f 682 SUPERFAMILY SSF51230 611 679 3.4E-18 T 14-10-2018 IPR011053 Single hybrid motif Tharo_2944 807f0988798cec58d6f87f48b3b3344f 682 Pfam PF00364 Biotin-requiring enzyme 613 677 4.3E-14 T 14-10-2018 IPR000089 Biotin/lipoyl attachment Tharo_2944 807f0988798cec58d6f87f48b3b3344f 682 SUPERFAMILY SSF52440 1 113 1.08E-49 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Tharo_2944 807f0988798cec58d6f87f48b3b3344f 682 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 290 297 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Tharo_2944 807f0988798cec58d6f87f48b3b3344f 682 Pfam PF02785 Biotin carboxylase C-terminal domain 340 457 4.8E-29 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Tharo_2817 997206cc07838b8a1e13a81c686ccf40 303 Pfam PF13529 Peptidase_C39 like family 39 140 2.6E-5 T 14-10-2018 IPR039564 Peptidase C39-like Tharo_2817 997206cc07838b8a1e13a81c686ccf40 303 SUPERFAMILY SSF48452 203 283 8.02E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_2817 997206cc07838b8a1e13a81c686ccf40 303 Gene3D G3DSA:3.90.70.10 40 184 1.7E-9 T 14-10-2018 Tharo_2817 997206cc07838b8a1e13a81c686ccf40 303 Gene3D G3DSA:1.25.40.10 185 297 8.7E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_2817 997206cc07838b8a1e13a81c686ccf40 303 Pfam PF13432 Tetratricopeptide repeat 202 248 8.0E-6 T 14-10-2018 Tharo_2894 77b87572143462de1fb5f5d7ccf4bc45 96 SMART SM00530 36 90 4.5E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_2894 77b87572143462de1fb5f5d7ccf4bc45 96 SUPERFAMILY SSF47413 37 82 1.66E-11 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_2894 77b87572143462de1fb5f5d7ccf4bc45 96 Pfam PF01381 Helix-turn-helix 37 78 9.8E-10 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_2894 77b87572143462de1fb5f5d7ccf4bc45 96 Gene3D G3DSA:1.10.260.40 36 96 2.6E-21 T 14-10-2018 Tharo_1188 032a9c171e7d42dc2231e47a2889efa8 207 SUPERFAMILY SSF51366 4 202 8.79E-61 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Tharo_1188 032a9c171e7d42dc2231e47a2889efa8 207 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 4 205 41.56 T 14-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 Tharo_1188 032a9c171e7d42dc2231e47a2889efa8 207 Gene3D G3DSA:3.20.20.70 2 206 1.3E-65 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_1188 032a9c171e7d42dc2231e47a2889efa8 207 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 6 199 4.6E-44 T 14-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 Tharo_2926 639ad834caaa30c561e249201213446e 92 SUPERFAMILY SSF54909 5 83 2.25E-7 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel Tharo_0796 4410b98e19c5fdbd19a8d98955fa97bd 803 SUPERFAMILY SSF52096 496 800 1.28E-30 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_0796 4410b98e19c5fdbd19a8d98955fa97bd 803 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 193 299 5.1E-8 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 Tharo_0796 4410b98e19c5fdbd19a8d98955fa97bd 803 SUPERFAMILY SSF48179 192 315 1.36E-19 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Tharo_0796 4410b98e19c5fdbd19a8d98955fa97bd 803 Pfam PF00378 Enoyl-CoA hydratase/isomerase 511 633 2.4E-11 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Tharo_0796 4410b98e19c5fdbd19a8d98955fa97bd 803 Gene3D G3DSA:1.10.1040.10 195 316 3.2E-15 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Tharo_0796 4410b98e19c5fdbd19a8d98955fa97bd 803 SUPERFAMILY SSF51735 5 192 1.49E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_0796 4410b98e19c5fdbd19a8d98955fa97bd 803 SUPERFAMILY SSF48179 350 458 2.3E-16 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Tharo_0796 4410b98e19c5fdbd19a8d98955fa97bd 803 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 190 7.8E-44 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 Tharo_0796 4410b98e19c5fdbd19a8d98955fa97bd 803 Gene3D G3DSA:3.40.50.720 4 194 8.3E-55 T 14-10-2018 Tharo_0796 4410b98e19c5fdbd19a8d98955fa97bd 803 Gene3D G3DSA:3.90.226.10 492 702 3.6E-22 T 14-10-2018 Tharo_1721 fe387ba657f47b9e47422df4a302535e 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 323 9.1E-27 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Tharo_1721 fe387ba657f47b9e47422df4a302535e 325 SUPERFAMILY SSF161098 107 306 4.19E-13 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_1721 fe387ba657f47b9e47422df4a302535e 325 Gene3D G3DSA:1.10.3720.10 106 318 9.4E-16 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_2033 758f2bab1dd21b7ae9f9aab19376492a 1024 Gene3D G3DSA:1.25.40.20 579 771 1.1E-12 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily Tharo_2033 758f2bab1dd21b7ae9f9aab19376492a 1024 Pfam PF01443 Viral (Superfamily 1) RNA helicase 294 500 2.0E-5 T 14-10-2018 IPR027351 (+) RNA virus helicase core domain GO:0005524 Tharo_2033 758f2bab1dd21b7ae9f9aab19376492a 1024 Gene3D G3DSA:3.40.50.300 384 570 1.8E-8 T 14-10-2018 Tharo_2033 758f2bab1dd21b7ae9f9aab19376492a 1024 SUPERFAMILY SSF48403 696 765 3.42E-11 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily Tharo_2033 758f2bab1dd21b7ae9f9aab19376492a 1024 SUPERFAMILY SSF52540 139 566 2.84E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2033 758f2bab1dd21b7ae9f9aab19376492a 1024 Pfam PF12796 Ankyrin repeats (3 copies) 710 764 1.2E-6 T 14-10-2018 IPR020683 Ankyrin repeat-containing domain Tharo_2229 a32a54db0158b7cc21923814b530e03b 285 Gene3D G3DSA:3.60.10.10 1 285 1.8E-45 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Tharo_2229 a32a54db0158b7cc21923814b530e03b 285 SUPERFAMILY SSF56219 1 284 2.49E-32 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Tharo_2229 a32a54db0158b7cc21923814b530e03b 285 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 277 7.1E-13 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase Tharo_0163 ecdf421f88c2c192ab3caae8480d8e74 264 Pfam PF09339 IclR helix-turn-helix domain 25 71 9.2E-13 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Tharo_0163 ecdf421f88c2c192ab3caae8480d8e74 264 SUPERFAMILY SSF46785 22 94 1.91E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0163 ecdf421f88c2c192ab3caae8480d8e74 264 Pfam PF01614 Bacterial transcriptional regulator 138 252 1.1E-29 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal Tharo_0163 ecdf421f88c2c192ab3caae8480d8e74 264 Gene3D G3DSA:1.10.10.10 21 84 1.5E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0163 ecdf421f88c2c192ab3caae8480d8e74 264 SMART SM00346 22 110 4.9E-17 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Tharo_0163 ecdf421f88c2c192ab3caae8480d8e74 264 SUPERFAMILY SSF55781 96 263 2.68E-40 T 14-10-2018 Tharo_0163 ecdf421f88c2c192ab3caae8480d8e74 264 Gene3D G3DSA:3.30.450.40 86 264 5.4E-47 T 14-10-2018 IPR029016 GAF-like domain superfamily Tharo_3380 895f680d1c712047117e9b6cbead46f7 215 Pfam PF00484 Carbonic anhydrase 38 190 8.0E-50 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Tharo_3380 895f680d1c712047117e9b6cbead46f7 215 SUPERFAMILY SSF53056 3 211 9.81E-73 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 Tharo_3380 895f680d1c712047117e9b6cbead46f7 215 SMART SM00947 31 194 2.7E-63 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Tharo_3380 895f680d1c712047117e9b6cbead46f7 215 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 43 50 - T 14-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Tharo_3380 895f680d1c712047117e9b6cbead46f7 215 Gene3D G3DSA:3.40.1050.10 1 211 2.8E-83 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 Tharo_1982 d3ce1bce1c289a76af7840d65621ad4c 1139 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 359 369 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site Tharo_1982 d3ce1bce1c289a76af7840d65621ad4c 1139 Pfam PF03797 Autotransporter beta-domain 875 1118 7.7E-42 T 14-10-2018 IPR005546 Autotransporter beta-domain Tharo_1982 d3ce1bce1c289a76af7840d65621ad4c 1139 Gene3D G3DSA:2.40.128.130 855 1139 4.7E-52 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily Tharo_1982 d3ce1bce1c289a76af7840d65621ad4c 1139 PRINTS PR00723 Subtilisin serine protease family (S8) signature 139 152 8.6E-9 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Tharo_1982 d3ce1bce1c289a76af7840d65621ad4c 1139 PRINTS PR00723 Subtilisin serine protease family (S8) signature 358 374 8.6E-9 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Tharo_1982 d3ce1bce1c289a76af7840d65621ad4c 1139 PRINTS PR00723 Subtilisin serine protease family (S8) signature 73 92 8.6E-9 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related Tharo_1982 d3ce1bce1c289a76af7840d65621ad4c 1139 Pfam PF00082 Subtilase family 76 409 5.3E-37 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Tharo_1982 d3ce1bce1c289a76af7840d65621ad4c 1139 Pfam PF12951 Passenger-associated-transport-repeat 602 631 3.2E-7 T 14-10-2018 IPR013425 Autotransporter-associated beta strand repeat Tharo_1982 d3ce1bce1c289a76af7840d65621ad4c 1139 SUPERFAMILY SSF52743 55 423 1.96E-50 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 Tharo_1982 d3ce1bce1c289a76af7840d65621ad4c 1139 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 666 1137 2.9E-33 T 14-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 Tharo_1982 d3ce1bce1c289a76af7840d65621ad4c 1139 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 143 153 - T 14-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site Tharo_1982 d3ce1bce1c289a76af7840d65621ad4c 1139 SMART SM00869 872 1129 1.8E-31 T 14-10-2018 IPR005546 Autotransporter beta-domain Tharo_1982 d3ce1bce1c289a76af7840d65621ad4c 1139 SUPERFAMILY SSF103515 835 1139 8.76E-46 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily Tharo_1982 d3ce1bce1c289a76af7840d65621ad4c 1139 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 601 631 8.2E-9 T 14-10-2018 IPR013425 Autotransporter-associated beta strand repeat Tharo_1982 d3ce1bce1c289a76af7840d65621ad4c 1139 Gene3D G3DSA:3.40.50.200 32 419 8.3E-60 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 Tharo_3202 311a69f580d98af159cb9361b711d6fb 277 Gene3D G3DSA:3.10.310.10 5 272 4.1E-101 T 14-10-2018 Tharo_3202 311a69f580d98af159cb9361b711d6fb 277 Gene3D G3DSA:3.10.310.10 121 269 4.1E-101 T 14-10-2018 Tharo_3202 311a69f580d98af159cb9361b711d6fb 277 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 66 80 - T 14-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 Tharo_3202 311a69f580d98af159cb9361b711d6fb 277 SUPERFAMILY SSF54506 3 276 1.49E-54 T 14-10-2018 Tharo_3202 311a69f580d98af159cb9361b711d6fb 277 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 4 275 3.2E-90 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 Tharo_3202 311a69f580d98af159cb9361b711d6fb 277 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 276 38.594 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 Tharo_3202 311a69f580d98af159cb9361b711d6fb 277 Pfam PF01678 Diaminopimelate epimerase 154 268 1.1E-27 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 Tharo_3202 311a69f580d98af159cb9361b711d6fb 277 Pfam PF01678 Diaminopimelate epimerase 5 124 1.8E-33 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 Tharo_0655 22ee817bcee1dec7075bceee62531c6c 788 Pfam PF00437 Type II/IV secretion system protein 380 649 3.2E-69 T 14-10-2018 IPR001482 Type II/IV secretion system protein Tharo_0655 22ee817bcee1dec7075bceee62531c6c 788 SUPERFAMILY SSF55781 23 191 6.98E-21 T 14-10-2018 Tharo_0655 22ee817bcee1dec7075bceee62531c6c 788 Pfam PF01590 GAF domain 40 186 1.6E-7 T 14-10-2018 IPR003018 GAF domain GO:0005515 Tharo_0655 22ee817bcee1dec7075bceee62531c6c 788 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 577 591 - T 14-10-2018 IPR001482 Type II/IV secretion system protein Tharo_0655 22ee817bcee1dec7075bceee62531c6c 788 SMART SM00065 38 198 1.5E-7 T 14-10-2018 IPR003018 GAF domain GO:0005515 Tharo_0655 22ee817bcee1dec7075bceee62531c6c 788 Gene3D G3DSA:3.40.50.300 485 788 5.1E-100 T 14-10-2018 Tharo_0655 22ee817bcee1dec7075bceee62531c6c 788 SUPERFAMILY SSF160246 202 337 7.32E-11 T 14-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily Tharo_0655 22ee817bcee1dec7075bceee62531c6c 788 SUPERFAMILY SSF52540 371 785 1.01E-82 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0655 22ee817bcee1dec7075bceee62531c6c 788 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 239 339 4.3E-7 T 14-10-2018 IPR007831 General secretory system II, protein E, N-terminal Tharo_0655 22ee817bcee1dec7075bceee62531c6c 788 SMART SM00382 510 645 0.003 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0655 22ee817bcee1dec7075bceee62531c6c 788 Gene3D G3DSA:3.30.450.40 15 191 8.0E-24 T 14-10-2018 IPR029016 GAF-like domain superfamily Tharo_0655 22ee817bcee1dec7075bceee62531c6c 788 Gene3D G3DSA:3.30.450.90 350 483 1.9E-37 T 14-10-2018 Tharo_0719 d48daf9403da67a29d940ff6dba84b16 373 Gene3D G3DSA:3.40.50.150 20 208 6.1E-17 T 14-10-2018 Tharo_0719 d48daf9403da67a29d940ff6dba84b16 373 SUPERFAMILY SSF53335 18 196 6.75E-22 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_0719 d48daf9403da67a29d940ff6dba84b16 373 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 108 114 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Tharo_0719 d48daf9403da67a29d940ff6dba84b16 373 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 105 117 4.3E-8 T 14-10-2018 Tharo_0719 d48daf9403da67a29d940ff6dba84b16 373 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 134 158 4.3E-8 T 14-10-2018 Tharo_0719 d48daf9403da67a29d940ff6dba84b16 373 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 45 59 4.3E-8 T 14-10-2018 Tharo_0746 7e038f20f0c7eb495287f358d6d0a702 266 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 56 74 - T 14-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 Tharo_0746 7e038f20f0c7eb495287f358d6d0a702 266 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 265 37.155 T 14-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 Tharo_0746 7e038f20f0c7eb495287f358d6d0a702 266 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 263 2.5E-94 T 14-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 Tharo_0746 7e038f20f0c7eb495287f358d6d0a702 266 SUPERFAMILY SSF51366 1 264 3.3E-88 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Tharo_0746 7e038f20f0c7eb495287f358d6d0a702 266 Gene3D G3DSA:3.20.20.70 1 266 1.6E-104 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_2221 154583e367848ac7230ad53f3adb983b 253 SMART SM00345 20 78 4.9E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_2221 154583e367848ac7230ad53f3adb983b 253 Pfam PF07729 FCD domain 88 224 1.6E-15 T 14-10-2018 IPR011711 GntR, C-terminal Tharo_2221 154583e367848ac7230ad53f3adb983b 253 Gene3D G3DSA:1.20.120.530 81 233 4.2E-24 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Tharo_2221 154583e367848ac7230ad53f3adb983b 253 SMART SM00895 88 226 4.7E-15 T 14-10-2018 IPR011711 GntR, C-terminal Tharo_2221 154583e367848ac7230ad53f3adb983b 253 SUPERFAMILY SSF48008 84 231 3.14E-18 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Tharo_2221 154583e367848ac7230ad53f3adb983b 253 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 78 1.9E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_2221 154583e367848ac7230ad53f3adb983b 253 SUPERFAMILY SSF46785 13 107 1.09E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_2221 154583e367848ac7230ad53f3adb983b 253 Gene3D G3DSA:1.10.10.10 3 79 1.3E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0992 7b6f7112c8a76291b78f39b238382915 431 Pfam PF13393 Histidyl-tRNA synthetase 10 313 2.9E-47 T 14-10-2018 Tharo_0992 7b6f7112c8a76291b78f39b238382915 431 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 409 5.7E-152 T 14-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 Tharo_0992 7b6f7112c8a76291b78f39b238382915 431 Gene3D G3DSA:3.40.50.800 328 421 1.2E-21 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily Tharo_0992 7b6f7112c8a76291b78f39b238382915 431 Gene3D G3DSA:3.30.930.10 2 321 3.6E-120 T 14-10-2018 Tharo_0992 7b6f7112c8a76291b78f39b238382915 431 SUPERFAMILY SSF55681 6 317 4.58E-101 T 14-10-2018 Tharo_0992 7b6f7112c8a76291b78f39b238382915 431 PIRSF PIRSF001549 1 421 1.8E-110 T 14-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Tharo_0992 7b6f7112c8a76291b78f39b238382915 431 SUPERFAMILY SSF52954 329 422 1.96E-19 T 14-10-2018 Tharo_0992 7b6f7112c8a76291b78f39b238382915 431 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 3 420 32.201 T 14-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 Tharo_0992 7b6f7112c8a76291b78f39b238382915 431 Pfam PF03129 Anticodon binding domain 330 418 3.7E-9 T 14-10-2018 IPR004154 Anticodon-binding Tharo_2608 19ba2b6162a485fcb7e58121ea6c543f 92 Pfam PF09905 DNA-binding protein VF530 6 68 5.6E-33 T 14-10-2018 IPR018668 DNA-binding protein VF530-like GO:0003677 Tharo_2608 19ba2b6162a485fcb7e58121ea6c543f 92 Gene3D G3DSA:1.10.720.30 14 73 1.3E-28 T 14-10-2018 IPR036361 SAP domain superfamily Tharo_1342 03e1c38a93112f2826420a0ec1c7ebfb 298 Gene3D G3DSA:3.40.50.300 3 166 3.4E-38 T 14-10-2018 Tharo_1342 03e1c38a93112f2826420a0ec1c7ebfb 298 PIRSF PIRSF006230 1 273 4.4E-83 T 14-10-2018 IPR016478 GTPase, MTG1 Tharo_1342 03e1c38a93112f2826420a0ec1c7ebfb 298 Pfam PF01926 50S ribosome-binding GTPase 110 166 1.4E-14 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_1342 03e1c38a93112f2826420a0ec1c7ebfb 298 SUPERFAMILY SSF52540 3 179 8.22E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1342 03e1c38a93112f2826420a0ec1c7ebfb 298 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 1 268 1.8E-85 T 14-10-2018 IPR019991 GTP-binding protein, ribosome biogenesis Tharo_1342 03e1c38a93112f2826420a0ec1c7ebfb 298 Gene3D G3DSA:1.10.1580.10 168 261 2.1E-19 T 14-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily Tharo_1718 9e410b97de828d3be38a779b817e256c 632 Pfam PF13624 SurA N-terminal domain 1 161 5.7E-48 T 14-10-2018 Tharo_1718 9e410b97de828d3be38a779b817e256c 632 Pfam PF13616 PPIC-type PPIASE domain 265 368 9.9E-23 T 14-10-2018 Tharo_1718 9e410b97de828d3be38a779b817e256c 632 Gene3D G3DSA:3.10.50.40 265 369 2.1E-34 T 14-10-2018 Tharo_1718 9e410b97de828d3be38a779b817e256c 632 SUPERFAMILY SSF109998 39 234 1.37E-27 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily Tharo_1718 9e410b97de828d3be38a779b817e256c 632 Gene3D G3DSA:1.10.4030.30 238 382 2.1E-34 T 14-10-2018 Tharo_1718 9e410b97de828d3be38a779b817e256c 632 SUPERFAMILY SSF54534 261 370 3.07E-28 T 14-10-2018 Tharo_0550 9516700ace33eae21642d23a81613031 227 Gene3D G3DSA:3.40.50.1470 7 196 3.1E-66 T 14-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 Tharo_0550 9516700ace33eae21642d23a81613031 227 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 9 185 34.705 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 Tharo_0550 9516700ace33eae21642d23a81613031 227 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 10 192 4.2E-59 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 Tharo_0550 9516700ace33eae21642d23a81613031 227 Pfam PF01195 Peptidyl-tRNA hydrolase 11 191 7.3E-56 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 Tharo_0550 9516700ace33eae21642d23a81613031 227 SUPERFAMILY SSF53178 10 192 4.19E-65 T 14-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 Tharo_0404 20301fec523a72ae53e902e5953cb612 385 Pfam PF01312 FlhB HrpN YscU SpaS Family 8 347 4.7E-122 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 Tharo_0404 20301fec523a72ae53e902e5953cb612 385 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 209 227 2.6E-37 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 Tharo_0404 20301fec523a72ae53e902e5953cb612 385 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 303 324 2.6E-37 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 Tharo_0404 20301fec523a72ae53e902e5953cb612 385 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 229 246 2.6E-37 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 Tharo_0404 20301fec523a72ae53e902e5953cb612 385 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 273 288 2.6E-37 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 Tharo_0404 20301fec523a72ae53e902e5953cb612 385 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 11 33 2.6E-37 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 Tharo_0404 20301fec523a72ae53e902e5953cb612 385 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 8 353 9.9E-121 T 14-10-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 Tharo_0404 20301fec523a72ae53e902e5953cb612 385 SUPERFAMILY SSF160544 251 355 5.76E-38 T 14-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal Tharo_0404 20301fec523a72ae53e902e5953cb612 385 Gene3D G3DSA:3.40.1690.10 219 358 1.6E-54 T 14-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal Tharo_2812 be34bfbbac0679bf7193d6d9bed6db74 267 Gene3D G3DSA:3.40.50.300 1 231 1.2E-52 T 14-10-2018 Tharo_2812 be34bfbbac0679bf7193d6d9bed6db74 267 SMART SM00382 26 207 2.5E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2812 be34bfbbac0679bf7193d6d9bed6db74 267 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_2812 be34bfbbac0679bf7193d6d9bed6db74 267 SUPERFAMILY SSF52540 2 217 2.61E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2812 be34bfbbac0679bf7193d6d9bed6db74 267 Pfam PF00005 ABC transporter 18 159 6.4E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_3375 a3fd4dbdc5e1231ac6db962059e7b636 219 Pfam PF13670 Peptidase propeptide and YPEB domain 35 101 3.1E-16 T 14-10-2018 IPR025711 PepSY domain Tharo_3375 a3fd4dbdc5e1231ac6db962059e7b636 219 Pfam PF13670 Peptidase propeptide and YPEB domain 110 171 4.8E-13 T 14-10-2018 IPR025711 PepSY domain Tharo_2344 89027672151781e8451bf4dfcb24c3d8 220 Gene3D G3DSA:1.10.530.10 80 212 1.6E-22 T 14-10-2018 Tharo_2344 89027672151781e8451bf4dfcb24c3d8 220 Pfam PF01464 Transglycosylase SLT domain 91 183 8.6E-17 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 Tharo_2344 89027672151781e8451bf4dfcb24c3d8 220 SUPERFAMILY SSF53955 80 185 2.25E-28 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily Tharo_2743 28f2bdeb6295862cca29754e522a3c6a 468 SUPERFAMILY SSF56176 12 224 3.88E-66 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Tharo_2743 28f2bdeb6295862cca29754e522a3c6a 468 Gene3D G3DSA:3.30.465.40 23 241 1.9E-70 T 14-10-2018 Tharo_2743 28f2bdeb6295862cca29754e522a3c6a 468 Gene3D G3DSA:1.10.45.10 425 465 6.0E-13 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 Tharo_2743 28f2bdeb6295862cca29754e522a3c6a 468 Gene3D G3DSA:3.30.70.2740 343 424 4.2E-13 T 14-10-2018 Tharo_2743 28f2bdeb6295862cca29754e522a3c6a 468 SUPERFAMILY SSF55103 227 467 1.39E-73 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 Tharo_2743 28f2bdeb6295862cca29754e522a3c6a 468 Pfam PF02913 FAD linked oxidases, C-terminal domain 224 464 7.9E-65 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 Tharo_2743 28f2bdeb6295862cca29754e522a3c6a 468 Pfam PF01565 FAD binding domain 50 187 9.8E-37 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Tharo_1151 008a79200805b360b69d634492259c0b 269 Gene3D G3DSA:1.25.40.10 38 257 5.1E-64 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_1151 008a79200805b360b69d634492259c0b 269 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 13 254 2.3E-91 T 14-10-2018 IPR017689 Outer membrane protein assembly factor BamD Tharo_1151 008a79200805b360b69d634492259c0b 269 SUPERFAMILY SSF48452 38 215 1.54E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_1151 008a79200805b360b69d634492259c0b 269 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 8 249 38.39 T 14-10-2018 IPR017689 Outer membrane protein assembly factor BamD Tharo_1151 008a79200805b360b69d634492259c0b 269 Pfam PF13525 Outer membrane lipoprotein 39 241 1.2E-67 T 14-10-2018 IPR039565 Outer membrane lipoprotein BamD-like Tharo_2556 9e48637f49d9689e222fb01018a23795 378 Pfam PF03308 ArgK protein 19 247 7.6E-89 T 14-10-2018 Tharo_2556 9e48637f49d9689e222fb01018a23795 378 Gene3D G3DSA:3.40.50.300 44 248 3.3E-80 T 14-10-2018 Tharo_2556 9e48637f49d9689e222fb01018a23795 378 Pfam PF02625 XdhC and CoxI family 286 353 7.8E-25 T 14-10-2018 IPR003777 XdhC- CoxI Tharo_2556 9e48637f49d9689e222fb01018a23795 378 SMART SM00382 46 190 1.7E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2556 9e48637f49d9689e222fb01018a23795 378 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 14 247 3.8E-90 T 14-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Tharo_2556 9e48637f49d9689e222fb01018a23795 378 SUPERFAMILY SSF52540 9 246 2.57E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0803 6fe771cab1b5cf06400701c79d1cce6d 408 SUPERFAMILY SSF54292 40 125 5.13E-23 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Tharo_0803 6fe771cab1b5cf06400701c79d1cce6d 408 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 39 116 1.7E-11 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Tharo_0803 6fe771cab1b5cf06400701c79d1cce6d 408 Hamap MF_00430 Na(+)-translocating NADH-quinone reductase subunit F [nqrF]. 4 408 64.934 T 14-10-2018 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 Tharo_0803 6fe771cab1b5cf06400701c79d1cce6d 408 PIRSF PIRSF000044 1 408 8.8E-227 T 14-10-2018 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 Tharo_0803 6fe771cab1b5cf06400701c79d1cce6d 408 SUPERFAMILY SSF52343 258 404 2.75E-39 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_0803 6fe771cab1b5cf06400701c79d1cce6d 408 Pfam PF00175 Oxidoreductase NAD-binding domain 278 387 1.5E-16 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 Tharo_0803 6fe771cab1b5cf06400701c79d1cce6d 408 Pfam PF00970 Oxidoreductase FAD-binding domain 205 267 1.2E-9 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 Tharo_0803 6fe771cab1b5cf06400701c79d1cce6d 408 TIGRFAM TIGR01941 nqrF: NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit 6 408 1.1E-221 T 14-10-2018 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 Tharo_0803 6fe771cab1b5cf06400701c79d1cce6d 408 Gene3D G3DSA:3.40.50.80 268 407 1.7E-32 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_0803 6fe771cab1b5cf06400701c79d1cce6d 408 SUPERFAMILY SSF63380 106 273 4.05E-37 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Tharo_0803 6fe771cab1b5cf06400701c79d1cce6d 408 Gene3D G3DSA:2.40.30.10 127 265 1.2E-50 T 14-10-2018 Tharo_0803 6fe771cab1b5cf06400701c79d1cce6d 408 Gene3D G3DSA:3.10.20.30 36 126 1.4E-27 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Tharo_0874 84b5ce8cb63e2bb002fb37f70eb4a3a9 123 Gene3D G3DSA:1.10.260.40 2 114 5.0E-7 T 14-10-2018 Tharo_2422 eed0d12623263e36f7712e037004dc94 452 SUPERFAMILY SSF56954 31 450 1.31E-58 T 14-10-2018 Tharo_2422 eed0d12623263e36f7712e037004dc94 452 Gene3D G3DSA:1.20.1600.10 56 451 2.9E-57 T 14-10-2018 Tharo_2422 eed0d12623263e36f7712e037004dc94 452 Pfam PF02321 Outer membrane efflux protein 275 449 3.5E-24 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Tharo_2422 eed0d12623263e36f7712e037004dc94 452 Pfam PF02321 Outer membrane efflux protein 64 249 4.1E-20 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Tharo_0908 3deed918f6b08b9f71c4c73aa2abef37 457 SUPERFAMILY SSF53244 309 446 6.8E-35 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Tharo_0908 3deed918f6b08b9f71c4c73aa2abef37 457 Gene3D G3DSA:3.40.1190.10 91 312 9.2E-58 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Tharo_0908 3deed918f6b08b9f71c4c73aa2abef37 457 Pfam PF02875 Mur ligase family, glutamate ligase domain 311 377 2.0E-9 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Tharo_0908 3deed918f6b08b9f71c4c73aa2abef37 457 Pfam PF08245 Mur ligase middle domain 108 290 6.0E-23 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Tharo_0908 3deed918f6b08b9f71c4c73aa2abef37 457 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 447 57.998 T 14-10-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MetaCyc: PWY-7883 Tharo_0908 3deed918f6b08b9f71c4c73aa2abef37 457 SUPERFAMILY SSF51984 1 90 2.35E-21 T 14-10-2018 Tharo_0908 3deed918f6b08b9f71c4c73aa2abef37 457 SUPERFAMILY SSF53623 95 307 1.3E-50 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Tharo_0908 3deed918f6b08b9f71c4c73aa2abef37 457 Gene3D G3DSA:3.90.190.20 313 448 9.5E-26 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Tharo_0908 3deed918f6b08b9f71c4c73aa2abef37 457 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 446 2.8E-213 T 14-10-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MetaCyc: PWY-7883 Tharo_0908 3deed918f6b08b9f71c4c73aa2abef37 457 Gene3D G3DSA:3.40.50.720 1 90 7.9E-35 T 14-10-2018 Tharo_0908 3deed918f6b08b9f71c4c73aa2abef37 457 Pfam PF01225 Mur ligase family, catalytic domain 2 99 1.2E-18 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 Tharo_1224 0a2e79694d78fe00e908840d36ed5f87 65 SUPERFAMILY SSF143034 2 64 4.32E-25 T 14-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1224 0a2e79694d78fe00e908840d36ed5f87 65 Gene3D G3DSA:2.40.50.530 1 65 9.6E-23 T 14-10-2018 Tharo_1224 0a2e79694d78fe00e908840d36ed5f87 65 Pfam PF01632 Ribosomal protein L35 2 62 1.3E-26 T 14-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1224 0a2e79694d78fe00e908840d36ed5f87 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 6.8E-28 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Tharo_1224 0a2e79694d78fe00e908840d36ed5f87 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 9.0E-19 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Tharo_1224 0a2e79694d78fe00e908840d36ed5f87 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 9.0E-19 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Tharo_1224 0a2e79694d78fe00e908840d36ed5f87 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 9.0E-19 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Tharo_1224 0a2e79694d78fe00e908840d36ed5f87 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 14-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_1224 0a2e79694d78fe00e908840d36ed5f87 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.796 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Tharo_2641 72a0375a5c3da8273d5e5c0c121fb3d0 494 TIGRFAM TIGR01539 portal_lambda: phage portal protein, lambda family 10 456 2.6E-83 T 14-10-2018 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 Tharo_2641 72a0375a5c3da8273d5e5c0c121fb3d0 494 Pfam PF05136 Phage portal protein, lambda family 10 356 1.7E-105 T 14-10-2018 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 Tharo_0121 bcfbaeabad5d953d70778c1392fb5fee 245 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 13 244 35.519 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 Tharo_0121 bcfbaeabad5d953d70778c1392fb5fee 245 Gene3D G3DSA:3.40.50.150 28 245 1.1E-65 T 14-10-2018 Tharo_0121 bcfbaeabad5d953d70778c1392fb5fee 245 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 33 48 - T 14-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 Tharo_0121 bcfbaeabad5d953d70778c1392fb5fee 245 Pfam PF01209 ubiE/COQ5 methyltransferase family 16 244 9.2E-87 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 Tharo_0121 bcfbaeabad5d953d70778c1392fb5fee 245 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 153 167 - T 14-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 Tharo_0121 bcfbaeabad5d953d70778c1392fb5fee 245 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 22 244 2.2E-75 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 Tharo_0121 bcfbaeabad5d953d70778c1392fb5fee 245 SUPERFAMILY SSF53335 1 235 1.42E-44 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_0332 88971fb01af661c34f1adaf6f161816e 228 Gene3D G3DSA:2.30.30.910 86 220 3.8E-28 T 14-10-2018 Tharo_0332 88971fb01af661c34f1adaf6f161816e 228 Gene3D G3DSA:2.60.40.4070 100 191 3.8E-28 T 14-10-2018 Tharo_0332 88971fb01af661c34f1adaf6f161816e 228 Pfam PF03963 Flagellar hook capping protein - N-terminal region 7 74 5.3E-20 T 14-10-2018 IPR005648 Flagellar hook capping protein Tharo_0332 88971fb01af661c34f1adaf6f161816e 228 Pfam PF13861 FlgD Tudor-like domain 85 225 1.8E-11 T 14-10-2018 IPR025963 FlgD Tudor-like domain Tharo_0332 88971fb01af661c34f1adaf6f161816e 228 Pfam PF13860 FlgD Ig-like domain 115 182 9.1E-21 T 14-10-2018 IPR025965 FlgD Ig-like domain Tharo_2971 3d1376b764d78e737349cd26cb78d253 149 SUPERFAMILY SSF55804 1 135 8.24E-42 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 Tharo_2971 3d1376b764d78e737349cd26cb78d253 149 Gene3D G3DSA:3.40.930.10 1 138 1.5E-51 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 Tharo_2971 3d1376b764d78e737349cd26cb78d253 149 TIGRFAM TIGR01419 nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN 3 134 4.6E-45 T 14-10-2018 IPR006320 Phosphotransferase system, IIA-like nitrogen-regulatory protein PtsN GO:0008982|GO:0009401 Tharo_2971 3d1376b764d78e737349cd26cb78d253 149 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 1 135 1.5E-34 T 14-10-2018 IPR002178 PTS EIIA type-2 domain Tharo_2971 3d1376b764d78e737349cd26cb78d253 149 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 40 56 - T 14-10-2018 IPR002178 PTS EIIA type-2 domain Tharo_1264 e526bdf4def728dc00e354d344d27570 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 60 3.6E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_1264 e526bdf4def728dc00e354d344d27570 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 8.7E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_1264 e526bdf4def728dc00e354d344d27570 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 8.7E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_1264 e526bdf4def728dc00e354d344d27570 212 Gene3D G3DSA:1.10.10.60 1 52 9.4E-18 T 14-10-2018 Tharo_1264 e526bdf4def728dc00e354d344d27570 212 SUPERFAMILY SSF48498 86 193 4.45E-10 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Tharo_1264 e526bdf4def728dc00e354d344d27570 212 SUPERFAMILY SSF46689 5 76 7.77E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_1264 e526bdf4def728dc00e354d344d27570 212 Gene3D G3DSA:1.10.357.10 55 197 9.4E-28 T 14-10-2018 Tharo_1214 9d5164406927178a800219ef9c2a02de 391 SMART SM00028 180 213 25.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Tharo_1214 9d5164406927178a800219ef9c2a02de 391 SMART SM00028 214 247 29.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Tharo_1214 9d5164406927178a800219ef9c2a02de 391 SMART SM00028 36 69 63.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Tharo_1214 9d5164406927178a800219ef9c2a02de 391 SMART SM00028 70 103 180.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Tharo_1214 9d5164406927178a800219ef9c2a02de 391 Gene3D G3DSA:1.25.40.10 175 312 1.1E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_1214 9d5164406927178a800219ef9c2a02de 391 Gene3D G3DSA:1.25.40.10 21 174 3.5E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_1214 9d5164406927178a800219ef9c2a02de 391 SUPERFAMILY SSF48452 42 248 1.26E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_1214 9d5164406927178a800219ef9c2a02de 391 Pfam PF13432 Tetratricopeptide repeat 185 237 1.0E-4 T 14-10-2018 Tharo_1214 9d5164406927178a800219ef9c2a02de 391 Pfam PF13432 Tetratricopeptide repeat 49 90 0.019 T 14-10-2018 Tharo_1214 9d5164406927178a800219ef9c2a02de 391 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 6 386 34.079 T 14-10-2018 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 Tharo_1555 99e8f29bc0beb23cd4c364bb2e3a1872 109 PIRSF PIRSF005894 1 108 1.0E-49 T 14-10-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 Tharo_1555 99e8f29bc0beb23cd4c364bb2e3a1872 109 Gene3D G3DSA:3.40.30.10 6 103 2.5E-33 T 14-10-2018 Tharo_1555 99e8f29bc0beb23cd4c364bb2e3a1872 109 SUPERFAMILY SSF52833 1 105 7.73E-36 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_1555 99e8f29bc0beb23cd4c364bb2e3a1872 109 Pfam PF00462 Glutaredoxin 16 81 4.0E-19 T 14-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 Tharo_1555 99e8f29bc0beb23cd4c364bb2e3a1872 109 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 4 101 9.6E-47 T 14-10-2018 IPR004480 Monothiol glutaredoxin-related Tharo_2081 86c95c360bb23bee90b9023d34539db1 64 TIGRFAM TIGR03412 iscX_yfhJ: FeS assembly protein IscX 2 63 2.7E-35 T 14-10-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 Tharo_2081 86c95c360bb23bee90b9023d34539db1 64 Pfam PF04384 Iron-sulphur cluster assembly 1 63 3.1E-32 T 14-10-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 Tharo_2081 86c95c360bb23bee90b9023d34539db1 64 PIRSF PIRSF039003 1 64 6.0E-35 T 14-10-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 Tharo_2081 86c95c360bb23bee90b9023d34539db1 64 Gene3D G3DSA:1.10.10.600 1 64 9.8E-30 T 14-10-2018 IPR036762 IscX-like superfamily Tharo_2081 86c95c360bb23bee90b9023d34539db1 64 SUPERFAMILY SSF140319 1 62 6.02E-27 T 14-10-2018 IPR036762 IscX-like superfamily Tharo_2039 76f6baee076e637b7fb8c7f7f7f0c8db 271 SUPERFAMILY SSF53474 20 271 7.5E-48 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_2039 76f6baee076e637b7fb8c7f7f7f0c8db 271 Pfam PF12697 Alpha/beta hydrolase family 27 264 1.8E-19 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_2039 76f6baee076e637b7fb8c7f7f7f0c8db 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 7.9E-13 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_2039 76f6baee076e637b7fb8c7f7f7f0c8db 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 7.9E-13 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_2039 76f6baee076e637b7fb8c7f7f7f0c8db 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 216 230 7.9E-13 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_2039 76f6baee076e637b7fb8c7f7f7f0c8db 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 7.9E-13 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_2039 76f6baee076e637b7fb8c7f7f7f0c8db 271 Gene3D G3DSA:3.40.50.1820 19 270 7.8E-57 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_0915 b56087457bd9d74aab98e95a8b919956 147 Pfam PF02381 MraZ protein, putative antitoxin-like 1 73 1.0E-12 T 14-10-2018 IPR020603 MraZ domain Tharo_0915 b56087457bd9d74aab98e95a8b919956 147 Pfam PF02381 MraZ protein, putative antitoxin-like 79 130 4.7E-15 T 14-10-2018 IPR020603 MraZ domain Tharo_0915 b56087457bd9d74aab98e95a8b919956 147 SUPERFAMILY SSF89447 1 135 5.67E-39 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily Tharo_0915 b56087457bd9d74aab98e95a8b919956 147 Gene3D G3DSA:2.40.330.20 1 136 8.3E-36 T 14-10-2018 IPR038619 MraZ superfamily Tharo_0915 b56087457bd9d74aab98e95a8b919956 147 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 128 6.0E-51 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 Tharo_0915 b56087457bd9d74aab98e95a8b919956 147 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 147 46.881 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 Tharo_0915 b56087457bd9d74aab98e95a8b919956 147 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 132 2.2E-37 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 Tharo_2569 e0158d911a508d3c883a478999ae4db1 138 Pfam PF13470 PIN domain 2 115 9.4E-11 T 14-10-2018 IPR002716 PIN domain Tharo_2569 e0158d911a508d3c883a478999ae4db1 138 Gene3D G3DSA:3.40.50.1010 1 124 1.4E-7 T 14-10-2018 Tharo_2569 e0158d911a508d3c883a478999ae4db1 138 SUPERFAMILY SSF88723 1 129 8.5E-18 T 14-10-2018 IPR029060 PIN-like domain superfamily Tharo_0423 14e1d1ce11ba84871cd4661d2125a1db 951 SUPERFAMILY SSF53335 161 591 4.68E-40 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_0423 14e1d1ce11ba84871cd4661d2125a1db 951 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 366 380 7.6E-6 T 14-10-2018 Tharo_0423 14e1d1ce11ba84871cd4661d2125a1db 951 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 476 488 7.6E-6 T 14-10-2018 Tharo_0423 14e1d1ce11ba84871cd4661d2125a1db 951 Pfam PF02384 N-6 DNA Methylase 357 488 2.8E-5 T 14-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 Tharo_0423 14e1d1ce11ba84871cd4661d2125a1db 951 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 479 485 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Tharo_1235 2f5feb96d252d5c8f7bbaa4dbdeaa5cb 267 Pfam PF09955 Predicted integral membrane protein (DUF2189) 77 195 3.7E-26 T 14-10-2018 IPR018692 Predicted integral membrane protein DUF2189 Tharo_2015 3d91ab90eae5858cc11aef34887abf92 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 277 3.6E-10 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Tharo_2015 3d91ab90eae5858cc11aef34887abf92 280 SUPERFAMILY SSF161098 73 269 3.92E-23 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_2015 3d91ab90eae5858cc11aef34887abf92 280 Gene3D G3DSA:1.10.3720.10 67 279 4.4E-26 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_1024 f51f19f07803fda8b091e161c1d7da48 300 Pfam PF02535 ZIP Zinc transporter 144 295 3.9E-16 T 14-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 Tharo_1182 bae3b6713972810fd7987e2e73792abc 212 SUPERFAMILY SSF52016 1 204 2.75E-60 T 14-10-2018 Tharo_1182 bae3b6713972810fd7987e2e73792abc 212 Pfam PF00694 Aconitase C-terminal domain 1 132 4.0E-36 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 Tharo_1182 bae3b6713972810fd7987e2e73792abc 212 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 210 42.762 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 Tharo_1182 bae3b6713972810fd7987e2e73792abc 212 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 196 1.2E-86 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 Tharo_1182 bae3b6713972810fd7987e2e73792abc 212 Gene3D G3DSA:3.20.19.10 1 184 2.1E-74 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 Tharo_3036 fd51a5af374706b98427dfa0eeb0f346 327 Gene3D G3DSA:3.30.43.10 1 60 5.5E-12 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 Tharo_3036 fd51a5af374706b98427dfa0eeb0f346 327 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 5 323 1.8E-60 T 14-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Tharo_3036 fd51a5af374706b98427dfa0eeb0f346 327 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 327 80.082 T 14-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Tharo_3036 fd51a5af374706b98427dfa0eeb0f346 327 Gene3D G3DSA:3.30.465.10 63 216 6.0E-53 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Tharo_3036 fd51a5af374706b98427dfa0eeb0f346 327 SUPERFAMILY SSF56176 2 184 2.83E-37 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Tharo_3036 fd51a5af374706b98427dfa0eeb0f346 327 SUPERFAMILY SSF56194 203 327 5.75E-44 T 14-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Tharo_3036 fd51a5af374706b98427dfa0eeb0f346 327 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 204 327 1.6E-32 T 14-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Tharo_3036 fd51a5af374706b98427dfa0eeb0f346 327 Gene3D G3DSA:3.90.78.10 217 327 3.5E-41 T 14-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Tharo_3036 fd51a5af374706b98427dfa0eeb0f346 327 Pfam PF01565 FAD binding domain 14 137 2.2E-19 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Tharo_0609 33bc1a0b18622af095c8dcc8a4f3d135 253 Pfam PF01553 Acyltransferase 59 182 2.4E-19 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Tharo_0609 33bc1a0b18622af095c8dcc8a4f3d135 253 SUPERFAMILY SSF69593 11 220 8.76E-38 T 14-10-2018 Tharo_0609 33bc1a0b18622af095c8dcc8a4f3d135 253 SMART SM00563 71 185 3.1E-33 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Tharo_3396 e6ec245138cc2f7db838214c0561e1f4 1072 SMART SM00487 277 508 1.6E-7 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Tharo_3396 e6ec245138cc2f7db838214c0561e1f4 1072 Gene3D G3DSA:3.40.50.300 309 493 9.0E-46 T 14-10-2018 Tharo_3396 e6ec245138cc2f7db838214c0561e1f4 1072 Gene3D G3DSA:3.90.1570.50 92 263 1.3E-26 T 14-10-2018 Tharo_3396 e6ec245138cc2f7db838214c0561e1f4 1072 SUPERFAMILY SSF52540 426 712 3.59E-5 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3396 e6ec245138cc2f7db838214c0561e1f4 1072 Gene3D G3DSA:3.40.50.300 494 739 3.8E-42 T 14-10-2018 Tharo_3396 e6ec245138cc2f7db838214c0561e1f4 1072 Pfam PF11867 Domain of unknown function (DUF3387) 727 1065 1.4E-124 T 14-10-2018 IPR021810 Protein of unknown function DUF3387 Tharo_3396 e6ec245138cc2f7db838214c0561e1f4 1072 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 4 215 1.3E-42 T 14-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 Tharo_3396 e6ec245138cc2f7db838214c0561e1f4 1072 Pfam PF04851 Type III restriction enzyme, res subunit 319 475 2.1E-13 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 Tharo_3396 e6ec245138cc2f7db838214c0561e1f4 1072 SUPERFAMILY SSF52540 231 518 1.84E-21 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3396 e6ec245138cc2f7db838214c0561e1f4 1072 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 317 729 8.9E-125 T 14-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 Tharo_3073 9c50d429b4b69f2d03ae6867fb07d629 567 SUPERFAMILY SSF53300 401 562 7.12E-15 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Tharo_3073 9c50d429b4b69f2d03ae6867fb07d629 567 Gene3D G3DSA:3.40.50.410 399 554 1.2E-9 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Tharo_2246 45e37e5705370e3e8b80b375a9bbd95f 223 Pfam PF04989 Cephalosporin hydroxylase 28 222 1.1E-62 T 14-10-2018 IPR007072 Rhamnosyl O-methyltransferase/Cephalosporin hydroxylase GO:0008168|GO:0008610 Tharo_2246 45e37e5705370e3e8b80b375a9bbd95f 223 SUPERFAMILY SSF53335 13 222 7.75E-29 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_2246 45e37e5705370e3e8b80b375a9bbd95f 223 Gene3D G3DSA:3.40.50.150 41 212 9.9E-31 T 14-10-2018 Tharo_2788 ae22b2e02dc6753a0cd0ffffdbb49bff 159 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 122 1.3E-22 T 14-10-2018 Tharo_2788 ae22b2e02dc6753a0cd0ffffdbb49bff 159 SUPERFAMILY SSF54593 3 150 8.24E-17 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Tharo_2788 ae22b2e02dc6753a0cd0ffffdbb49bff 159 Gene3D G3DSA:3.10.180.10 7 148 8.7E-21 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Tharo_0754 c7e3ee21fbfd4c3045daae6bf0e94fdf 211 PIRSF PIRSF005413 2 208 1.7E-61 T 14-10-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0754 c7e3ee21fbfd4c3045daae6bf0e94fdf 211 Gene3D G3DSA:2.60.370.10 75 208 1.8E-44 T 14-10-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0754 c7e3ee21fbfd4c3045daae6bf0e94fdf 211 Pfam PF04442 Cytochrome c oxidase assembly protein CtaG/Cox11 34 192 2.2E-47 T 14-10-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0754 c7e3ee21fbfd4c3045daae6bf0e94fdf 211 SUPERFAMILY SSF110111 76 195 6.41E-45 T 14-10-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_3288 1aeb3afb907e31a5b1ddb7467af8769f 456 Pfam PF04055 Radical SAM superfamily 81 235 5.2E-14 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_3288 1aeb3afb907e31a5b1ddb7467af8769f 456 SUPERFAMILY SSF102114 71 400 1.02E-44 T 14-10-2018 Tharo_3288 1aeb3afb907e31a5b1ddb7467af8769f 456 Gene3D G3DSA:3.20.20.70 75 435 2.9E-59 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_3288 1aeb3afb907e31a5b1ddb7467af8769f 456 TIGRFAM TIGR04163 rSAM_cobopep: peptide-modifying radical SAM enzyme CbpB 15 441 3.8E-209 T 14-10-2018 IPR026423 Peptide-modifying radical SAM enzyme CbpB Tharo_3288 1aeb3afb907e31a5b1ddb7467af8769f 456 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 327 413 1.5E-12 T 14-10-2018 IPR023885 4Fe4S-binding SPASM domain Tharo_1296 745657d52e391a33744bb7b71b38b204 215 Gene3D G3DSA:3.30.70.20 1 38 1.3E-9 T 14-10-2018 Tharo_1296 745657d52e391a33744bb7b71b38b204 215 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 90 101 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_1296 745657d52e391a33744bb7b71b38b204 215 SUPERFAMILY SSF54862 1 211 1.67E-61 T 14-10-2018 Tharo_1296 745657d52e391a33744bb7b71b38b204 215 Gene3D G3DSA:3.30.70.20 39 215 9.6E-52 T 14-10-2018 Tharo_1296 745657d52e391a33744bb7b71b38b204 215 Pfam PF13247 4Fe-4S dicluster domain 52 107 1.0E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_2968 0ee35212f366f9f1f444df62ff266ae8 241 SUPERFAMILY SSF52540 3 237 5.77E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2968 0ee35212f366f9f1f444df62ff266ae8 241 Gene3D G3DSA:3.40.50.300 2 241 1.6E-69 T 14-10-2018 Tharo_2968 0ee35212f366f9f1f444df62ff266ae8 241 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 214 236 2.0E-5 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal Tharo_2968 0ee35212f366f9f1f444df62ff266ae8 241 Pfam PF00005 ABC transporter 20 166 5.2E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_2968 0ee35212f366f9f1f444df62ff266ae8 241 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 4 241 2.4E-117 T 14-10-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 Tharo_2968 0ee35212f366f9f1f444df62ff266ae8 241 SMART SM00382 28 231 3.2E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0099 8b61ffc3a1efb02736f624e85fedcddc 273 Pfam PF02634 FdhD/NarQ family 33 273 2.8E-74 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 Tharo_0099 8b61ffc3a1efb02736f624e85fedcddc 273 SUPERFAMILY SSF53927 14 272 9.02E-82 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Tharo_0099 8b61ffc3a1efb02736f624e85fedcddc 273 Gene3D G3DSA:3.10.20.10 35 118 2.1E-7 T 14-10-2018 Tharo_0099 8b61ffc3a1efb02736f624e85fedcddc 273 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 9 273 34.85 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 Tharo_0099 8b61ffc3a1efb02736f624e85fedcddc 273 PIRSF PIRSF015626 2 273 5.9E-83 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 Tharo_0099 8b61ffc3a1efb02736f624e85fedcddc 273 Gene3D G3DSA:3.40.140.10 130 273 1.2E-49 T 14-10-2018 Tharo_0099 8b61ffc3a1efb02736f624e85fedcddc 273 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 29 273 4.4E-67 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 Tharo_1839 f5fa678063b1d7dbc5b7a200403b60e3 611 Gene3D G3DSA:3.30.565.10 451 598 1.7E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1839 f5fa678063b1d7dbc5b7a200403b60e3 611 Pfam PF00512 His Kinase A (phospho-acceptor) domain 379 446 2.0E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1839 f5fa678063b1d7dbc5b7a200403b60e3 611 SMART SM00387 487 597 3.2E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1839 f5fa678063b1d7dbc5b7a200403b60e3 611 Gene3D G3DSA:3.30.450.20 53 257 2.6E-72 T 14-10-2018 Tharo_1839 f5fa678063b1d7dbc5b7a200403b60e3 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 544 554 1.1E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1839 f5fa678063b1d7dbc5b7a200403b60e3 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 581 594 1.1E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1839 f5fa678063b1d7dbc5b7a200403b60e3 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 526 540 1.1E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1839 f5fa678063b1d7dbc5b7a200403b60e3 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 557 575 1.1E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1839 f5fa678063b1d7dbc5b7a200403b60e3 611 SMART SM00388 379 447 7.3E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1839 f5fa678063b1d7dbc5b7a200403b60e3 611 Gene3D G3DSA:1.10.287.130 355 442 1.2E-18 T 14-10-2018 Tharo_1839 f5fa678063b1d7dbc5b7a200403b60e3 611 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 490 594 3.6E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1839 f5fa678063b1d7dbc5b7a200403b60e3 611 SUPERFAMILY SSF103190 60 196 3.73E-17 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily Tharo_1839 f5fa678063b1d7dbc5b7a200403b60e3 611 Pfam PF02743 Cache domain 48 225 8.5E-17 T 14-10-2018 IPR033479 Double Cache domain 1 Tharo_1839 f5fa678063b1d7dbc5b7a200403b60e3 611 Gene3D G3DSA:3.30.450.20 65 186 2.6E-72 T 14-10-2018 Tharo_1839 f5fa678063b1d7dbc5b7a200403b60e3 611 SUPERFAMILY SSF55874 461 597 2.75E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1839 f5fa678063b1d7dbc5b7a200403b60e3 611 PIRSF PIRSF036431 11 602 1.1E-187 T 14-10-2018 IPR017055 Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator) Tharo_1839 f5fa678063b1d7dbc5b7a200403b60e3 611 SUPERFAMILY SSF47384 375 443 1.51E-10 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_1801 b0f2e4607a8e8a20af4905ded46c459f 251 Pfam PF03352 Methyladenine glycosylase 7 112 3.2E-47 T 14-10-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 Tharo_1801 b0f2e4607a8e8a20af4905ded46c459f 251 SUPERFAMILY SSF48150 3 142 2.35E-48 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 Tharo_1801 b0f2e4607a8e8a20af4905ded46c459f 251 Gene3D G3DSA:1.10.340.30 2 145 7.1E-50 T 14-10-2018 Tharo_2687 8ae354fc2b422b2fcd5f2b1dce8a2c4f 167 Hamap MF_00286 Disulfide bond formation protein B [dsbB]. 8 167 22.108 T 14-10-2018 IPR022920 Disulphide bond formation protein DsbB Tharo_2687 8ae354fc2b422b2fcd5f2b1dce8a2c4f 167 Gene3D G3DSA:1.20.1550.10 6 166 3.7E-50 T 14-10-2018 IPR023380 DsbB-like superfamily Tharo_2687 8ae354fc2b422b2fcd5f2b1dce8a2c4f 167 Pfam PF02600 Disulfide bond formation protein DsbB 13 163 1.9E-43 T 14-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 Tharo_2687 8ae354fc2b422b2fcd5f2b1dce8a2c4f 167 SUPERFAMILY SSF158442 16 164 1.09E-43 T 14-10-2018 IPR023380 DsbB-like superfamily Tharo_1186 b45a70c941dda7d7aaa050f626b7e1b9 218 Pfam PF02361 Cobalt transport protein 24 162 4.2E-8 T 14-10-2018 IPR003339 ABC/ECF transporter, transmembrane component Tharo_3439 4b4005e1f5f45f11661f2f79949fb437 279 Pfam PF00809 Pterin binding enzyme 5 248 2.6E-69 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_3439 4b4005e1f5f45f11661f2f79949fb437 279 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 38 51 - T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_3439 4b4005e1f5f45f11661f2f79949fb437 279 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 4 19 - T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_3439 4b4005e1f5f45f11661f2f79949fb437 279 Gene3D G3DSA:3.20.20.20 1 270 2.0E-67 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_3439 4b4005e1f5f45f11661f2f79949fb437 279 SUPERFAMILY SSF51717 3 265 1.7E-66 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_3439 4b4005e1f5f45f11661f2f79949fb437 279 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 4 262 4.8E-82 T 14-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 Tharo_0979 eacfd71010e2956e16c3a3b96f9e168a 321 Gene3D G3DSA:3.90.226.10 1 318 6.0E-120 T 14-10-2018 Tharo_0979 eacfd71010e2956e16c3a3b96f9e168a 321 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 316 50.208 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Tharo_0979 eacfd71010e2956e16c3a3b96f9e168a 321 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 319 1.5E-152 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Tharo_0979 eacfd71010e2956e16c3a3b96f9e168a 321 SUPERFAMILY SSF52096 5 316 2.87E-101 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_0979 eacfd71010e2956e16c3a3b96f9e168a 321 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 148 1.5E-66 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Tharo_0979 eacfd71010e2956e16c3a3b96f9e168a 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 153 166 5.1E-47 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Tharo_0979 eacfd71010e2956e16c3a3b96f9e168a 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 113 131 5.1E-47 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Tharo_0979 eacfd71010e2956e16c3a3b96f9e168a 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 88 99 5.1E-47 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Tharo_0979 eacfd71010e2956e16c3a3b96f9e168a 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 197 206 5.1E-47 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Tharo_0979 eacfd71010e2956e16c3a3b96f9e168a 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 169 182 5.1E-47 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Tharo_0979 eacfd71010e2956e16c3a3b96f9e168a 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 134 150 5.1E-47 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Tharo_2450 b8c64c014bed7ef14086fb3aa2d7aa82 346 Gene3D G3DSA:3.90.1200.10 93 342 3.5E-73 T 14-10-2018 Tharo_2450 b8c64c014bed7ef14086fb3aa2d7aa82 346 Gene3D G3DSA:3.30.200.20 1 92 3.0E-21 T 14-10-2018 Tharo_2450 b8c64c014bed7ef14086fb3aa2d7aa82 346 Pfam PF01636 Phosphotransferase enzyme family 23 255 1.2E-26 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase Tharo_2450 b8c64c014bed7ef14086fb3aa2d7aa82 346 SUPERFAMILY SSF56112 4 338 2.96E-58 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Tharo_0347 79d695ea3ba9f3a9dab3c684a0e531cc 156 Pfam PF03748 Flagellar basal body-associated protein FliL 55 156 4.3E-21 T 14-10-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 Tharo_1998 2950873cf8b3761c61504af58019afb6 486 Pfam PF02219 Methylenetetrahydrofolate reductase 171 459 7.6E-37 T 14-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 Tharo_1998 2950873cf8b3761c61504af58019afb6 486 Gene3D G3DSA:3.20.20.220 170 464 1.4E-58 T 14-10-2018 Tharo_1998 2950873cf8b3761c61504af58019afb6 486 Pfam PF12225 Methylene-tetrahydrofolate reductase C terminal 48 119 2.9E-24 T 14-10-2018 IPR022026 Methylene-tetrahydrofolate reductase C-terminal Tharo_1998 2950873cf8b3761c61504af58019afb6 486 SUPERFAMILY SSF51730 169 461 4.9E-68 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like Tharo_2582 8e043eb14956d5399fa353890786caa6 364 Gene3D G3DSA:3.30.2300.20 91 185 3.9E-27 T 14-10-2018 Tharo_2582 8e043eb14956d5399fa353890786caa6 364 Gene3D G3DSA:3.40.50.150 186 363 5.2E-54 T 14-10-2018 Tharo_2582 8e043eb14956d5399fa353890786caa6 364 PIRSF PIRSF028774 12 364 6.4E-123 T 14-10-2018 IPR011224 Ribosomal RNA large subunit methyltransferase M GO:0008168 Tharo_2582 8e043eb14956d5399fa353890786caa6 364 Hamap MF_01551 Ribosomal RNA large subunit methyltransferase M [rlmM]. 12 363 73.789 T 14-10-2018 IPR011224 Ribosomal RNA large subunit methyltransferase M GO:0008168 Tharo_2582 8e043eb14956d5399fa353890786caa6 364 Pfam PF01728 FtsJ-like methyltransferase 196 290 2.2E-7 T 14-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 Tharo_2582 8e043eb14956d5399fa353890786caa6 364 SUPERFAMILY SSF53335 195 313 2.15E-15 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_2582 8e043eb14956d5399fa353890786caa6 364 Gene3D G3DSA:3.30.70.2810 13 88 3.2E-18 T 14-10-2018 Tharo_2170 8605687c2f7a579c6d6bf55228c8a5c9 151 SUPERFAMILY SSF54534 1 131 2.55E-29 T 14-10-2018 Tharo_2170 8605687c2f7a579c6d6bf55228c8a5c9 151 Gene3D G3DSA:2.40.10.330 62 112 1.6E-48 T 14-10-2018 Tharo_2170 8605687c2f7a579c6d6bf55228c8a5c9 151 Gene3D G3DSA:3.10.50.40 1 145 1.6E-48 T 14-10-2018 Tharo_2170 8605687c2f7a579c6d6bf55228c8a5c9 151 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 1 81 6.0E-5 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain Tharo_1353 20a3f9a0c57a0efcf1e3d809432a1e81 140 Pfam PF02033 Ribosome-binding factor A 7 110 3.6E-30 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 Tharo_1353 20a3f9a0c57a0efcf1e3d809432a1e81 140 SUPERFAMILY SSF89919 3 112 4.58E-33 T 14-10-2018 IPR023799 Ribosome-binding factor A domain superfamily Tharo_1353 20a3f9a0c57a0efcf1e3d809432a1e81 140 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 4 115 5.1E-31 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 Tharo_1353 20a3f9a0c57a0efcf1e3d809432a1e81 140 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 6 110 25.78 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 Tharo_1353 20a3f9a0c57a0efcf1e3d809432a1e81 140 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 97 8.0E-38 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 Tharo_1353 20a3f9a0c57a0efcf1e3d809432a1e81 140 Gene3D G3DSA:3.30.300.20 1 104 3.3E-34 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta Tharo_0276 fb326e48654879ab44bedc71086402ab 554 Gene3D G3DSA:2.40.10.200 439 540 3.5E-26 T 14-10-2018 Tharo_0276 fb326e48654879ab44bedc71086402ab 554 SUPERFAMILY SSF46785 419 545 3.81E-43 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0276 fb326e48654879ab44bedc71086402ab 554 Gene3D G3DSA:1.10.10.10 423 493 3.5E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0276 fb326e48654879ab44bedc71086402ab 554 Gene3D G3DSA:1.10.3210.40 3 220 4.6E-38 T 14-10-2018 Tharo_0276 fb326e48654879ab44bedc71086402ab 554 TIGRFAM TIGR03760 ICE_TraI_Pfluor: integrating conjugative element relaxase, PFGI-1 class 2 215 2.6E-89 T 14-10-2018 IPR022391 Integrating conjugative element relaxase, PFGI-1 class Tharo_0276 fb326e48654879ab44bedc71086402ab 554 Pfam PF07514 Putative helicase 3 312 7.8E-127 T 14-10-2018 IPR011119 Uncharacterised domain, helicase/relaxase, putative Tharo_0276 fb326e48654879ab44bedc71086402ab 554 Pfam PF07515 Putative conjugal transfer nickase/helicase TraI C-term 422 544 3.5E-50 T 14-10-2018 IPR011093 Putative conjugal transfer nickase/helicase TraI, C-terminal Tharo_2825 2c3509eb33c85f941b680a065f33ca59 100 SUPERFAMILY SSF102829 6 94 1.23E-18 T 14-10-2018 IPR036192 Cell division protein ZapA-like superfamily Tharo_2825 2c3509eb33c85f941b680a065f33ca59 100 Gene3D G3DSA:1.20.5.50 49 98 2.3E-5 T 14-10-2018 Tharo_2825 2c3509eb33c85f941b680a065f33ca59 100 Pfam PF05164 Cell division protein ZapA 7 88 3.1E-17 T 14-10-2018 IPR007838 Cell division protein ZapA-like Tharo_2825 2c3509eb33c85f941b680a065f33ca59 100 Gene3D G3DSA:1.10.20.30 2 44 3.1E-11 T 14-10-2018 Tharo_2336 77329be998702638fc751743f652029e 139 SUPERFAMILY SSF82784 1 137 2.09E-39 T 14-10-2018 IPR036102 OsmC/Ohr superfamily Tharo_2336 77329be998702638fc751743f652029e 139 Gene3D G3DSA:2.20.25.10 1 33 3.7E-8 T 14-10-2018 Tharo_2336 77329be998702638fc751743f652029e 139 Gene3D G3DSA:3.30.300.20 39 138 1.5E-27 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta Tharo_2336 77329be998702638fc751743f652029e 139 Pfam PF02566 OsmC-like protein 34 131 6.6E-16 T 14-10-2018 IPR003718 OsmC/Ohr family Tharo_3224 e025827d584114a8ae7d223769caf92e 197 Pfam PF05685 Putative restriction endonuclease 12 178 3.8E-32 T 14-10-2018 IPR008538 Domain of unknown function DUF820 Tharo_3224 e025827d584114a8ae7d223769caf92e 197 Gene3D G3DSA:3.90.1570.10 4 186 8.6E-18 T 14-10-2018 Tharo_3224 e025827d584114a8ae7d223769caf92e 197 SUPERFAMILY SSF52980 8 183 1.88E-23 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Tharo_0777 08851ce5c2e81ab3537820db89baec1c 329 Gene3D G3DSA:2.40.50.100 44 190 4.0E-29 T 14-10-2018 Tharo_0777 08851ce5c2e81ab3537820db89baec1c 329 Gene3D G3DSA:2.40.420.20 261 284 4.0E-29 T 14-10-2018 Tharo_0777 08851ce5c2e81ab3537820db89baec1c 329 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 33 206 2.6E-31 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Tharo_0777 08851ce5c2e81ab3537820db89baec1c 329 Pfam PF13437 HlyD family secretion protein 155 241 1.5E-7 T 14-10-2018 Tharo_0777 08851ce5c2e81ab3537820db89baec1c 329 Gene3D G3DSA:1.10.287.470 78 151 4.0E-29 T 14-10-2018 Tharo_0777 08851ce5c2e81ab3537820db89baec1c 329 Gene3D G3DSA:2.40.30.170 36 260 4.0E-29 T 14-10-2018 Tharo_0777 08851ce5c2e81ab3537820db89baec1c 329 SUPERFAMILY SSF111369 36 187 3.4E-12 T 14-10-2018 Tharo_1692 f329745937098415e3841051f13bcb50 76 Pfam PF10981 Protein of unknown function (DUF2788) 23 72 7.1E-23 T 14-10-2018 IPR021249 Protein of unknown function DUF2788 Tharo_0042 656d23796f75e29a1625e9a0b9f4f58a 151 SUPERFAMILY SSF141322 83 150 6.41E-7 T 14-10-2018 Tharo_0042 656d23796f75e29a1625e9a0b9f4f58a 151 Pfam PF01957 NfeD-like C-terminal, partner-binding 11 150 4.7E-15 T 14-10-2018 IPR002810 NfeD-like, C-terminal domain Tharo_0042 656d23796f75e29a1625e9a0b9f4f58a 151 Gene3D G3DSA:2.40.50.140 82 151 2.5E-7 T 14-10-2018 Tharo_2283 ada8bf541712c23ee9fc35cc006fe03c 141 Pfam PF09278 MerR, DNA binding 52 114 5.1E-15 T 14-10-2018 IPR015358 Transcription regulator MerR, DNA binding Tharo_2283 ada8bf541712c23ee9fc35cc006fe03c 141 Pfam PF00376 MerR family regulatory protein 10 47 1.0E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Tharo_2283 ada8bf541712c23ee9fc35cc006fe03c 141 SUPERFAMILY SSF46955 9 132 3.04E-29 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily Tharo_2283 ada8bf541712c23ee9fc35cc006fe03c 141 SMART SM00422 9 78 2.8E-21 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Tharo_2283 ada8bf541712c23ee9fc35cc006fe03c 141 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 10 21 1.3E-17 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Tharo_2283 ada8bf541712c23ee9fc35cc006fe03c 141 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 45 65 1.3E-17 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Tharo_2283 ada8bf541712c23ee9fc35cc006fe03c 141 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 21 34 1.3E-17 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Tharo_2283 ada8bf541712c23ee9fc35cc006fe03c 141 Gene3D G3DSA:1.10.1660.10 2 132 5.4E-32 T 14-10-2018 Tharo_3358 c7d4fba7b954c32e2cce13fe0a034379 330 Gene3D G3DSA:3.20.20.70 17 291 4.1E-25 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_3358 c7d4fba7b954c32e2cce13fe0a034379 330 SUPERFAMILY SSF102114 10 304 1.96E-31 T 14-10-2018 Tharo_3358 c7d4fba7b954c32e2cce13fe0a034379 330 Pfam PF04055 Radical SAM superfamily 24 153 1.4E-11 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_2041 888f161b756b39a88363987e768a80aa 228 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 7 225 27.849 T 14-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 Tharo_2041 888f161b756b39a88363987e768a80aa 228 Gene3D G3DSA:3.40.50.300 8 225 1.9E-65 T 14-10-2018 Tharo_2041 888f161b756b39a88363987e768a80aa 228 PIRSF PIRSF006755 6 226 1.4E-64 T 14-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 Tharo_2041 888f161b756b39a88363987e768a80aa 228 Pfam PF13500 AAA domain 9 214 1.2E-36 T 14-10-2018 Tharo_2041 888f161b756b39a88363987e768a80aa 228 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 11 181 1.1E-43 T 14-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 Tharo_2041 888f161b756b39a88363987e768a80aa 228 SUPERFAMILY SSF52540 8 214 1.38E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2290 884ad8abd0275a875cf8fd8f6445cb75 478 SMART SM01027 257 382 8.6E-49 T 14-10-2018 IPR022712 Beta-Casp domain Tharo_2290 884ad8abd0275a875cf8fd8f6445cb75 478 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 396 458 2.4E-15 T 14-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain Tharo_2290 884ad8abd0275a875cf8fd8f6445cb75 478 Gene3D G3DSA:3.60.15.10 6 443 2.1E-134 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_2290 884ad8abd0275a875cf8fd8f6445cb75 478 Pfam PF00753 Metallo-beta-lactamase superfamily 10 118 3.7E-14 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_2290 884ad8abd0275a875cf8fd8f6445cb75 478 SMART SM00849 13 240 6.7E-13 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_2290 884ad8abd0275a875cf8fd8f6445cb75 478 Pfam PF10996 Beta-Casp domain 257 382 9.1E-21 T 14-10-2018 IPR022712 Beta-Casp domain Tharo_2290 884ad8abd0275a875cf8fd8f6445cb75 478 Gene3D G3DSA:3.40.50.10890 224 408 2.1E-134 T 14-10-2018 Tharo_2290 884ad8abd0275a875cf8fd8f6445cb75 478 SUPERFAMILY SSF56281 1 469 1.17E-121 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_0881 9be8944cf7c63b85e2f0a38e34d6eb41 384 Gene3D G3DSA:2.40.50.100 59 225 1.4E-66 T 14-10-2018 Tharo_0881 9be8944cf7c63b85e2f0a38e34d6eb41 384 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 35 363 1.3E-42 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Tharo_0881 9be8944cf7c63b85e2f0a38e34d6eb41 384 SUPERFAMILY SSF111369 47 207 1.18E-10 T 14-10-2018 Tharo_0881 9be8944cf7c63b85e2f0a38e34d6eb41 384 Gene3D G3DSA:2.40.420.20 43 361 1.4E-66 T 14-10-2018 Tharo_0881 9be8944cf7c63b85e2f0a38e34d6eb41 384 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 60 287 1.5E-14 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Tharo_0881 9be8944cf7c63b85e2f0a38e34d6eb41 384 Gene3D G3DSA:1.10.287.470 93 184 1.4E-66 T 14-10-2018 Tharo_0881 9be8944cf7c63b85e2f0a38e34d6eb41 384 Gene3D G3DSA:2.40.30.170 46 306 1.4E-66 T 14-10-2018 Tharo_2049 66eb6313ec41071377c8518e9d4bdbc8 1153 SUPERFAMILY SSF52540 48 336 5.8E-5 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1726 cded915c10fbb0cff7e9290f96cb4b2b 554 Gene3D G3DSA:1.20.1250.20 324 552 3.9E-62 T 14-10-2018 Tharo_1726 cded915c10fbb0cff7e9290f96cb4b2b 554 Gene3D G3DSA:1.20.1250.20 7 253 3.7E-74 T 14-10-2018 Tharo_1726 cded915c10fbb0cff7e9290f96cb4b2b 554 SUPERFAMILY SSF103473 41 548 1.13E-23 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_1726 cded915c10fbb0cff7e9290f96cb4b2b 554 Pfam PF07690 Major Facilitator Superfamily 349 550 1.9E-8 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_1297 728dce71add169801f76fd32bc1b6da8 914 Pfam PF01568 Molydopterin dinucleotide binding domain 806 868 4.2E-11 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 Tharo_1297 728dce71add169801f76fd32bc1b6da8 914 SUPERFAMILY SSF50692 779 912 9.04E-18 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Tharo_1297 728dce71add169801f76fd32bc1b6da8 914 Gene3D G3DSA:2.20.25.90 5 71 6.5E-6 T 14-10-2018 Tharo_1297 728dce71add169801f76fd32bc1b6da8 914 Pfam PF00384 Molybdopterin oxidoreductase 71 627 1.4E-29 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1297 728dce71add169801f76fd32bc1b6da8 914 SUPERFAMILY SSF53706 11 621 6.15E-114 T 14-10-2018 Tharo_1297 728dce71add169801f76fd32bc1b6da8 914 Gene3D G3DSA:3.40.50.740 72 177 4.2E-12 T 14-10-2018 Tharo_1297 728dce71add169801f76fd32bc1b6da8 914 Gene3D G3DSA:3.40.50.740 490 652 6.9E-20 T 14-10-2018 Tharo_1297 728dce71add169801f76fd32bc1b6da8 914 Gene3D G3DSA:2.40.40.20 754 914 7.6E-18 T 14-10-2018 Tharo_2685 b3b6d9c5ad3020d862b1d1c326bdb27a 199 SUPERFAMILY SSF52218 1 197 4.94E-59 T 14-10-2018 IPR029039 Flavoprotein-like superfamily Tharo_2685 b3b6d9c5ad3020d862b1d1c326bdb27a 199 Gene3D G3DSA:3.40.50.360 1 198 1.4E-62 T 14-10-2018 IPR029039 Flavoprotein-like superfamily Tharo_2685 b3b6d9c5ad3020d862b1d1c326bdb27a 199 Pfam PF02525 Flavodoxin-like fold 1 196 1.4E-48 T 14-10-2018 IPR003680 Flavodoxin-like fold Tharo_2685 b3b6d9c5ad3020d862b1d1c326bdb27a 199 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 198 31.668 T 14-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 Tharo_2728 62bfbec3458e2d407dea92848857759b 155 PIRSF PIRSF002122 3 155 7.5E-55 T 14-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 Tharo_2728 62bfbec3458e2d407dea92848857759b 155 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 14-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2728 62bfbec3458e2d407dea92848857759b 155 SUPERFAMILY SSF47973 2 148 1.44E-57 T 14-10-2018 IPR036823 Ribosomal protein S7 domain superfamily Tharo_2728 62bfbec3458e2d407dea92848857759b 155 Pfam PF00177 Ribosomal protein S7p/S5e 1 148 1.7E-65 T 14-10-2018 IPR023798 Ribosomal protein S7 domain Tharo_2728 62bfbec3458e2d407dea92848857759b 155 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 155 35.079 T 14-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 Tharo_2728 62bfbec3458e2d407dea92848857759b 155 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 154 1.4E-64 T 14-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 Tharo_2728 62bfbec3458e2d407dea92848857759b 155 Gene3D G3DSA:1.10.455.10 2 154 4.9E-59 T 14-10-2018 IPR036823 Ribosomal protein S7 domain superfamily Tharo_3349 caef537f4d15e0f9d8a1ebf3d6b3173e 566 SUPERFAMILY SSF46785 427 484 3.08E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_3349 caef537f4d15e0f9d8a1ebf3d6b3173e 566 Gene3D G3DSA:3.30.950.30 4 128 8.3E-22 T 14-10-2018 IPR038461 Schlafen, AAA domain superfamily Tharo_3349 caef537f4d15e0f9d8a1ebf3d6b3173e 566 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 310 392 3.8E-18 T 14-10-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain Tharo_3349 caef537f4d15e0f9d8a1ebf3d6b3173e 566 Pfam PF04326 Putative DNA-binding domain 19 123 1.2E-14 T 14-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 Tharo_3349 caef537f4d15e0f9d8a1ebf3d6b3173e 566 Gene3D G3DSA:3.30.565.60 239 398 1.2E-40 T 14-10-2018 IPR038475 RecG, C-terminal domain superfamily Tharo_3450 d70abd245d912e713f6c6f73bf32eff4 178 Pfam PF10502 Signal peptidase, peptidase S26 32 177 3.5E-43 T 14-10-2018 IPR019533 Peptidase S26 Tharo_3450 d70abd245d912e713f6c6f73bf32eff4 178 SUPERFAMILY SSF51306 32 176 3.14E-17 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily Tharo_3450 d70abd245d912e713f6c6f73bf32eff4 178 Gene3D G3DSA:2.10.109.10 79 177 1.7E-10 T 14-10-2018 Tharo_3450 d70abd245d912e713f6c6f73bf32eff4 178 TIGRFAM TIGR02771 TraF_Ti: conjugative transfer signal peptidase TraF 12 178 1.7E-61 T 14-10-2018 IPR014139 Peptidase S26C, conjugative transfer signal peptidase TraF GO:0000746|GO:0042597 Tharo_3312 45aece39c3a84cf0d288638f5ee69cdd 421 Pfam PF01966 HD domain 232 351 6.6E-18 T 14-10-2018 IPR006674 HD domain Tharo_3312 45aece39c3a84cf0d288638f5ee69cdd 421 Gene3D G3DSA:1.10.3210.10 209 403 3.9E-67 T 14-10-2018 Tharo_3312 45aece39c3a84cf0d288638f5ee69cdd 421 SUPERFAMILY SSF109604 220 390 2.33E-39 T 14-10-2018 Tharo_3312 45aece39c3a84cf0d288638f5ee69cdd 421 SMART SM00471 226 361 1.6E-5 T 14-10-2018 IPR003607 HD/PDEase domain Tharo_3312 45aece39c3a84cf0d288638f5ee69cdd 421 TIGRFAM TIGR00277 HDIG: HDIG domain 231 321 5.8E-8 T 14-10-2018 IPR006675 HDIG domain Tharo_1660 a784127131f92193e46c639e7ec9b3d8 173 TIGRFAM TIGR00077 lspA: signal peptidase II 22 165 3.5E-44 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Tharo_1660 a784127131f92193e46c639e7ec9b3d8 173 ProSitePatterns PS00855 Signal peptidases II signature. 114 126 - T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Tharo_1660 a784127131f92193e46c639e7ec9b3d8 173 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 111 126 9.8E-18 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Tharo_1660 a784127131f92193e46c639e7ec9b3d8 173 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 147 163 9.8E-18 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Tharo_1660 a784127131f92193e46c639e7ec9b3d8 173 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 64 72 9.8E-18 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Tharo_1660 a784127131f92193e46c639e7ec9b3d8 173 Pfam PF01252 Signal peptidase (SPase) II 27 164 2.1E-38 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Tharo_1660 a784127131f92193e46c639e7ec9b3d8 173 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 18 172 16.642 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Tharo_2513 378b6577a1c3b7351c68c5c3229932b5 307 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 25 253 1.8E-92 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Tharo_2513 378b6577a1c3b7351c68c5c3229932b5 307 Gene3D G3DSA:1.10.1270.20 188 278 1.0E-33 T 14-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Tharo_2513 378b6577a1c3b7351c68c5c3229932b5 307 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 45 247 4.2E-59 T 14-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Tharo_2513 378b6577a1c3b7351c68c5c3229932b5 307 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 307 111.286 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Tharo_2513 378b6577a1c3b7351c68c5c3229932b5 307 SUPERFAMILY SSF75217 24 270 1.9E-97 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases Tharo_2513 378b6577a1c3b7351c68c5c3229932b5 307 Gene3D G3DSA:3.40.1280.10 23 187 1.2E-63 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Tharo_1574 734286e8b85db1648ed9013eb18008e5 168 PIRSF PIRSF000194 1 165 1.9E-61 T 14-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 Tharo_1574 734286e8b85db1648ed9013eb18008e5 168 Gene3D G3DSA:3.40.430.10 5 167 1.0E-57 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 Tharo_1574 734286e8b85db1648ed9013eb18008e5 168 Pfam PF00186 Dihydrofolate reductase 6 162 5.2E-57 T 14-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 Tharo_1574 734286e8b85db1648ed9013eb18008e5 168 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 17 39 - T 14-10-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 Tharo_1574 734286e8b85db1648ed9013eb18008e5 168 SUPERFAMILY SSF53597 2 163 1.17E-55 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 Tharo_1574 734286e8b85db1648ed9013eb18008e5 168 PRINTS PR00070 Dihydrofolate reductase signature 31 39 1.6E-16 T 14-10-2018 Tharo_1574 734286e8b85db1648ed9013eb18008e5 168 PRINTS PR00070 Dihydrofolate reductase signature 94 108 1.6E-16 T 14-10-2018 Tharo_1574 734286e8b85db1648ed9013eb18008e5 168 PRINTS PR00070 Dihydrofolate reductase signature 44 55 1.6E-16 T 14-10-2018 Tharo_1574 734286e8b85db1648ed9013eb18008e5 168 PRINTS PR00070 Dihydrofolate reductase signature 17 27 1.6E-16 T 14-10-2018 Tharo_2273 8eae43452201ad9f1294f34c4e39c863 121 SUPERFAMILY SSF52172 3 120 9.68E-36 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_2273 8eae43452201ad9f1294f34c4e39c863 121 SMART SM00448 3 116 1.6E-37 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2273 8eae43452201ad9f1294f34c4e39c863 121 Pfam PF00072 Response regulator receiver domain 5 116 4.0E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2273 8eae43452201ad9f1294f34c4e39c863 121 Gene3D G3DSA:3.40.50.12740 1 121 3.2E-38 T 14-10-2018 Tharo_0548 a96614fb58a2986e01b55446e7cf11fc 681 SUPERFAMILY SSF158472 310 359 1.7E-5 T 14-10-2018 Tharo_0548 a96614fb58a2986e01b55446e7cf11fc 681 Gene3D G3DSA:1.20.1480.50 269 364 1.6E-5 T 14-10-2018 Tharo_0548 a96614fb58a2986e01b55446e7cf11fc 681 Pfam PF02743 Cache domain 48 271 4.6E-16 T 14-10-2018 IPR033479 Double Cache domain 1 Tharo_0548 a96614fb58a2986e01b55446e7cf11fc 681 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 549 673 5.5E-26 T 14-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 Tharo_0548 a96614fb58a2986e01b55446e7cf11fc 681 SMART SM00267 364 532 2.4E-55 T 14-10-2018 IPR000160 GGDEF domain Tharo_0548 a96614fb58a2986e01b55446e7cf11fc 681 Gene3D G3DSA:1.20.120.50 545 677 1.9E-24 T 14-10-2018 IPR035938 Hemerythrin-like superfamily Tharo_0548 a96614fb58a2986e01b55446e7cf11fc 681 Gene3D G3DSA:3.30.450.20 37 180 9.9E-13 T 14-10-2018 Tharo_0548 a96614fb58a2986e01b55446e7cf11fc 681 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 371 531 2.6E-46 T 14-10-2018 IPR000160 GGDEF domain Tharo_0548 a96614fb58a2986e01b55446e7cf11fc 681 SUPERFAMILY SSF55073 380 530 6.28E-47 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_0548 a96614fb58a2986e01b55446e7cf11fc 681 Gene3D G3DSA:3.30.70.270 365 532 1.2E-54 T 14-10-2018 Tharo_0548 a96614fb58a2986e01b55446e7cf11fc 681 ProSitePatterns PS00550 Hemerythrin family signature. 602 625 - T 14-10-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 Tharo_0548 a96614fb58a2986e01b55446e7cf11fc 681 SUPERFAMILY SSF47188 548 673 1.06E-23 T 14-10-2018 IPR035938 Hemerythrin-like superfamily Tharo_0548 a96614fb58a2986e01b55446e7cf11fc 681 Pfam PF00990 Diguanylate cyclase, GGDEF domain 376 528 4.9E-42 T 14-10-2018 IPR000160 GGDEF domain Tharo_0548 a96614fb58a2986e01b55446e7cf11fc 681 Pfam PF01814 Hemerythrin HHE cation binding domain 560 673 3.1E-9 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 Tharo_0548 a96614fb58a2986e01b55446e7cf11fc 681 SMART SM00304 309 362 5.3E-4 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_0865 b91b959fe2a89c90e06eca5859899867 622 SUPERFAMILY SSF52518 12 209 3.07E-57 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_0865 b91b959fe2a89c90e06eca5859899867 622 SUPERFAMILY SSF54862 539 608 6.47E-9 T 14-10-2018 Tharo_0865 b91b959fe2a89c90e06eca5859899867 622 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 25 179 3.2E-14 T 14-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 Tharo_0865 b91b959fe2a89c90e06eca5859899867 622 Pfam PF13237 4Fe-4S dicluster domain 546 601 2.5E-7 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_0865 b91b959fe2a89c90e06eca5859899867 622 Gene3D G3DSA:3.30.70.20 539 621 2.0E-7 T 14-10-2018 Tharo_0865 b91b959fe2a89c90e06eca5859899867 622 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 377 524 7.6E-25 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Tharo_0865 b91b959fe2a89c90e06eca5859899867 622 Gene3D G3DSA:3.40.50.970 3 188 3.5E-53 T 14-10-2018 Tharo_0865 b91b959fe2a89c90e06eca5859899867 622 SUPERFAMILY SSF52518 349 536 5.49E-33 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_0865 b91b959fe2a89c90e06eca5859899867 622 PIRSF PIRSF006439 1 613 2.2E-231 T 14-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 Tharo_0865 b91b959fe2a89c90e06eca5859899867 622 Gene3D G3DSA:3.40.50.970 366 538 9.3E-22 T 14-10-2018 Tharo_2444 9d87f8bc18a43165f20ff3ebe2992531 254 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 253 1.3E-73 T 14-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 Tharo_2444 9d87f8bc18a43165f20ff3ebe2992531 254 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 253 4.6E-77 T 14-10-2018 Tharo_2444 9d87f8bc18a43165f20ff3ebe2992531 254 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 210 221 - T 14-10-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 Tharo_2444 9d87f8bc18a43165f20ff3ebe2992531 254 Gene3D G3DSA:3.60.10.10 1 253 2.0E-73 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Tharo_2444 9d87f8bc18a43165f20ff3ebe2992531 254 SUPERFAMILY SSF56219 1 253 1.44E-79 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Tharo_2444 9d87f8bc18a43165f20ff3ebe2992531 254 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 246 8.2E-25 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase Tharo_1619 410582d31d6adb6bb7728eaca8afae8a 250 Pfam PF02565 Recombination protein O C terminal 90 242 3.1E-20 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 Tharo_1619 410582d31d6adb6bb7728eaca8afae8a 250 Hamap MF_00201 DNA repair protein RecO [recO]. 7 247 22.47 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 Tharo_1619 410582d31d6adb6bb7728eaca8afae8a 250 SUPERFAMILY SSF57863 92 163 4.45E-7 T 14-10-2018 IPR037278 ARFGAP/RecO-like zinc finger Tharo_1619 410582d31d6adb6bb7728eaca8afae8a 250 Gene3D G3DSA:2.40.50.140 8 82 5.7E-31 T 14-10-2018 Tharo_1619 410582d31d6adb6bb7728eaca8afae8a 250 TIGRFAM TIGR00613 reco: DNA repair protein RecO 14 247 3.2E-24 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 Tharo_1619 410582d31d6adb6bb7728eaca8afae8a 250 Pfam PF11967 Recombination protein O N terminal 10 82 4.3E-21 T 14-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal Tharo_1619 410582d31d6adb6bb7728eaca8afae8a 250 Gene3D G3DSA:1.20.1440.120 86 250 6.4E-46 T 14-10-2018 Tharo_1619 410582d31d6adb6bb7728eaca8afae8a 250 SUPERFAMILY SSF50249 7 81 2.06E-13 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_3170 50888cdb3c5a47cea1a130cd877981a9 568 SUPERFAMILY SSF52540 219 542 1.61E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3170 50888cdb3c5a47cea1a130cd877981a9 568 Pfam PF13538 UvrD-like helicase C-terminal domain 492 538 4.4E-8 T 14-10-2018 IPR027785 UvrD-like helicase C-terminal domain Tharo_3170 50888cdb3c5a47cea1a130cd877981a9 568 Gene3D G3DSA:3.40.50.300 208 369 6.5E-14 T 14-10-2018 Tharo_3199 3e6940e58bb2feca7296a4f5a5b9bc69 353 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 21 247 2.2E-118 T 14-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 Tharo_3199 3e6940e58bb2feca7296a4f5a5b9bc69 353 Gene3D G3DSA:1.10.8.60 194 268 1.3E-30 T 14-10-2018 Tharo_3199 3e6940e58bb2feca7296a4f5a5b9bc69 353 SUPERFAMILY SSF46785 268 342 3.7E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_3199 3e6940e58bb2feca7296a4f5a5b9bc69 353 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 35 338 7.6E-146 T 14-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 Tharo_3199 3e6940e58bb2feca7296a4f5a5b9bc69 353 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 265 338 6.8E-32 T 14-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 Tharo_3199 3e6940e58bb2feca7296a4f5a5b9bc69 353 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 262 343 4.0E-38 T 14-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 Tharo_3199 3e6940e58bb2feca7296a4f5a5b9bc69 353 Gene3D G3DSA:3.40.50.300 32 193 2.3E-39 T 14-10-2018 Tharo_3199 3e6940e58bb2feca7296a4f5a5b9bc69 353 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 353 182.731 T 14-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 Tharo_3199 3e6940e58bb2feca7296a4f5a5b9bc69 353 SMART SM00382 63 191 7.6E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_3199 3e6940e58bb2feca7296a4f5a5b9bc69 353 SUPERFAMILY SSF52540 32 263 2.81E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3199 3e6940e58bb2feca7296a4f5a5b9bc69 353 Gene3D G3DSA:1.10.10.10 269 346 6.0E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_3020 495b575287cc56e8506330dc21054f12 605 TIGRFAM TIGR01863 cas_Csd1: CRISPR-associated protein Cas8c/Csd1, subtype I-C/DVULG 3 591 1.7E-177 T 14-10-2018 IPR010144 CRISPR-associated protein, Csd1-type Tharo_3020 495b575287cc56e8506330dc21054f12 605 Pfam PF09709 CRISPR-associated protein (Cas_Csd1) 6 586 1.7E-174 T 14-10-2018 IPR010144 CRISPR-associated protein, Csd1-type Tharo_2823 8fa6e1cd33f2e443e571cd8831d55038 651 SUPERFAMILY SSF49373 569 648 8.37E-5 T 14-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments Tharo_2823 8fa6e1cd33f2e443e571cd8831d55038 651 Gene3D G3DSA:3.40.390.10 256 405 3.6E-5 T 14-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 Tharo_2823 8fa6e1cd33f2e443e571cd8831d55038 651 SUPERFAMILY SSF55486 318 373 2.89E-9 T 14-10-2018 Tharo_2823 8fa6e1cd33f2e443e571cd8831d55038 651 Gene3D G3DSA:2.60.40.10 553 649 5.5E-5 T 14-10-2018 IPR013783 Immunoglobulin-like fold Tharo_2823 8fa6e1cd33f2e443e571cd8831d55038 651 Pfam PF05548 Gametolysin peptidase M11 287 413 4.6E-11 T 14-10-2018 IPR008752 Peptidase M11, gametolysin Tharo_2627 40800f35096667216b154081906df0f2 420 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 63 79 6.6E-5 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Tharo_2627 40800f35096667216b154081906df0f2 420 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 41 57 6.6E-5 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Tharo_2627 40800f35096667216b154081906df0f2 420 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 300 313 6.6E-5 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Tharo_2627 40800f35096667216b154081906df0f2 420 Pfam PF13458 Periplasmic binding protein 40 393 5.7E-63 T 14-10-2018 IPR028081 Leucine-binding protein domain Tharo_2627 40800f35096667216b154081906df0f2 420 Gene3D G3DSA:3.40.50.2300 166 294 3.8E-78 T 14-10-2018 Tharo_2627 40800f35096667216b154081906df0f2 420 Gene3D G3DSA:3.40.50.2300 42 364 3.8E-78 T 14-10-2018 Tharo_2627 40800f35096667216b154081906df0f2 420 SUPERFAMILY SSF53822 40 401 1.11E-81 T 14-10-2018 IPR028082 Periplasmic binding protein-like I Tharo_0501 e382f32eb636e0f928e1b7394221da77 99 Gene3D G3DSA:2.40.50.140 1 99 3.8E-29 T 14-10-2018 Tharo_0501 e382f32eb636e0f928e1b7394221da77 99 PIRSF PIRSF003135 1 97 6.9E-15 T 14-10-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 Tharo_0501 e382f32eb636e0f928e1b7394221da77 99 Hamap MF_00720 Primosomal replication protein N [priB]. 1 96 22.637 T 14-10-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 Tharo_0501 e382f32eb636e0f928e1b7394221da77 99 TIGRFAM TIGR04418 PriB_gamma: primosomal replication protein PriB 2 95 2.4E-29 T 14-10-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 Tharo_0501 e382f32eb636e0f928e1b7394221da77 99 SUPERFAMILY SSF50249 1 98 6.0E-18 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_0697 e5becc3d42fdc57d170f544096057bd8 969 Gene3D G3DSA:3.40.50.300 515 706 6.9E-9 T 14-10-2018 Tharo_0697 e5becc3d42fdc57d170f544096057bd8 969 Gene3D G3DSA:3.40.50.300 728 913 4.0E-17 T 14-10-2018 Tharo_0697 e5becc3d42fdc57d170f544096057bd8 969 TIGRFAM TIGR03744 traC_PFL_4706: conjugative transfer ATPase, PFL_4706 family 56 959 0.0 T 14-10-2018 IPR022303 Conjugative transfer ATPase Tharo_0697 e5becc3d42fdc57d170f544096057bd8 969 SUPERFAMILY SSF52540 489 883 1.12E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0697 e5becc3d42fdc57d170f544096057bd8 969 Pfam PF11130 F pilus assembly Type-IV secretion system for plasmid transfer 67 345 2.8E-72 T 14-10-2018 IPR025955 Type-IV secretion system protein TraC/Conjugative transfer ATPase Tharo_3432 dd402a14b507f46fa657321d5fb698fa 188 SUPERFAMILY SSF46689 139 182 3.4E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_3432 dd402a14b507f46fa657321d5fb698fa 188 SUPERFAMILY SSF53041 1 136 3.79E-45 T 14-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 Tharo_3432 dd402a14b507f46fa657321d5fb698fa 188 Gene3D G3DSA:3.40.50.1390 2 126 1.7E-48 T 14-10-2018 Tharo_3432 dd402a14b507f46fa657321d5fb698fa 188 SMART SM00857 3 137 8.1E-61 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 Tharo_3432 dd402a14b507f46fa657321d5fb698fa 188 Pfam PF00239 Resolvase, N terminal domain 4 137 3.0E-45 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 Tharo_3432 dd402a14b507f46fa657321d5fb698fa 188 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 14-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 Tharo_2361 5ff7710bedd91925a87e4e5476e1e267 181 Gene3D G3DSA:2.60.120.10 1 181 1.2E-75 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Tharo_2361 5ff7710bedd91925a87e4e5476e1e267 181 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 175 1.0E-81 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Tharo_2361 5ff7710bedd91925a87e4e5476e1e267 181 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 2 178 6.5E-84 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Tharo_2361 5ff7710bedd91925a87e4e5476e1e267 181 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 5 175 3.5E-74 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Tharo_2361 5ff7710bedd91925a87e4e5476e1e267 181 SUPERFAMILY SSF51182 1 179 3.29E-78 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily Tharo_1804 9dab286d2c3594a2e7254b1c76176888 376 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 3.0E-44 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Tharo_1804 9dab286d2c3594a2e7254b1c76176888 376 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 2 367 1.5E-146 T 14-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 Tharo_1804 9dab286d2c3594a2e7254b1c76176888 376 SUPERFAMILY SSF51735 137 303 1.35E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1804 9dab286d2c3594a2e7254b1c76176888 376 SUPERFAMILY SSF52283 2 360 6.12E-61 T 14-10-2018 Tharo_1804 9dab286d2c3594a2e7254b1c76176888 376 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 173 198 - T 14-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 Tharo_1804 9dab286d2c3594a2e7254b1c76176888 376 SMART SM01003 4 137 3.3E-76 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Tharo_1804 9dab286d2c3594a2e7254b1c76176888 376 Gene3D G3DSA:3.40.50.720 130 305 6.9E-132 T 14-10-2018 Tharo_1804 9dab286d2c3594a2e7254b1c76176888 376 PIRSF PIRSF000183 1 370 2.0E-147 T 14-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 Tharo_1804 9dab286d2c3594a2e7254b1c76176888 376 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 2.7E-75 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Tharo_1804 9dab286d2c3594a2e7254b1c76176888 376 Gene3D G3DSA:3.40.50.720 3 352 6.9E-132 T 14-10-2018 Tharo_1804 9dab286d2c3594a2e7254b1c76176888 376 SMART SM01002 149 297 7.5E-75 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Tharo_1030 342f37ecdab1a3711fbe486f6ab4c110 422 Pfam PF00033 Cytochrome b/b6/petB 27 222 6.5E-64 T 14-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 Tharo_1030 342f37ecdab1a3711fbe486f6ab4c110 422 SUPERFAMILY SSF81342 10 290 1.57E-96 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 Tharo_1030 342f37ecdab1a3711fbe486f6ab4c110 422 PIRSF PIRSF038885 1 422 2.8E-156 T 14-10-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 Tharo_1030 342f37ecdab1a3711fbe486f6ab4c110 422 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 288 397 2.3E-43 T 14-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 Tharo_1030 342f37ecdab1a3711fbe486f6ab4c110 422 Gene3D G3DSA:1.20.810.10 1 422 9.7E-160 T 14-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 Tharo_1030 342f37ecdab1a3711fbe486f6ab4c110 422 SUPERFAMILY SSF81648 291 410 8.83E-31 T 14-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 Tharo_0450 dbe222c94d23fcca4b112cf7a7f6eeb4 365 Gene3D G3DSA:3.40.640.10 34 252 3.4E-46 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_0450 dbe222c94d23fcca4b112cf7a7f6eeb4 365 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 204 217 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Tharo_0450 dbe222c94d23fcca4b112cf7a7f6eeb4 365 SUPERFAMILY SSF53383 3 338 8.41E-50 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_0450 dbe222c94d23fcca4b112cf7a7f6eeb4 365 TIGRFAM TIGR01140 L_thr_O3P_dcar: threonine-phosphate decarboxylase 4 338 7.6E-101 T 14-10-2018 IPR005860 L-threonine-O-3-phosphate decarboxylase GO:0003824|GO:0009236 KEGG: 00860+4.1.1.81|MetaCyc: PWY-5443 Tharo_0450 dbe222c94d23fcca4b112cf7a7f6eeb4 365 Pfam PF00155 Aminotransferase class I and II 132 301 5.4E-23 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Tharo_0450 dbe222c94d23fcca4b112cf7a7f6eeb4 365 Gene3D G3DSA:3.90.1150.10 22 315 3.4E-46 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_3336 115071f9b64a7ab332ebf8cf37fa9369 261 SUPERFAMILY SSF110399 3 245 6.41E-90 T 14-10-2018 Tharo_3336 115071f9b64a7ab332ebf8cf37fa9369 261 Gene3D G3DSA:3.20.20.70 1 260 2.3E-118 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_3336 115071f9b64a7ab332ebf8cf37fa9369 261 Hamap MF_00443 Thiazole synthase [thiG]. 4 260 42.55 T 14-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 Tharo_3336 115071f9b64a7ab332ebf8cf37fa9369 261 Pfam PF05690 Thiazole biosynthesis protein ThiG 7 254 9.0E-107 T 14-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 Tharo_1766 976812ed09de8f9d97444b35b465d301 335 Gene3D G3DSA:3.20.20.70 2 332 4.7E-126 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_1766 976812ed09de8f9d97444b35b465d301 335 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 289 309 - T 14-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 Tharo_1766 976812ed09de8f9d97444b35b465d301 335 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 2 333 49.532 T 14-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 Tharo_1766 976812ed09de8f9d97444b35b465d301 335 PIRSF PIRSF000164 12 335 5.8E-90 T 14-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 Tharo_1766 976812ed09de8f9d97444b35b465d301 335 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 3 332 2.8E-123 T 14-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 Tharo_1766 976812ed09de8f9d97444b35b465d301 335 Pfam PF01180 Dihydroorotate dehydrogenase 44 328 1.5E-82 T 14-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 Tharo_1766 976812ed09de8f9d97444b35b465d301 335 SUPERFAMILY SSF51395 1 331 1.03E-100 T 14-10-2018 Tharo_1766 976812ed09de8f9d97444b35b465d301 335 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 77 96 - T 14-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 Tharo_1282 9f999390104b77749e74ebbcac552fc0 480 TIGRFAM TIGR03906 quino_hemo_SAM: quinohemoprotein amine dehydrogenase maturation protein 10 476 9.3E-207 T 14-10-2018 IPR023886 Quinohemoprotein amine dehydrogenase, gamma subunit maturation protein Tharo_1282 9f999390104b77749e74ebbcac552fc0 480 SUPERFAMILY SSF102114 101 424 1.83E-47 T 14-10-2018 Tharo_1282 9f999390104b77749e74ebbcac552fc0 480 Pfam PF04055 Radical SAM superfamily 110 272 1.3E-11 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_1282 9f999390104b77749e74ebbcac552fc0 480 Gene3D G3DSA:3.20.20.70 101 462 6.4E-63 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_1282 9f999390104b77749e74ebbcac552fc0 480 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 110 121 - T 14-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Tharo_1282 9f999390104b77749e74ebbcac552fc0 480 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 355 443 1.6E-11 T 14-10-2018 IPR023885 4Fe4S-binding SPASM domain Tharo_1282 9f999390104b77749e74ebbcac552fc0 480 Pfam PF13353 4Fe-4S single cluster domain 112 230 1.6E-11 T 14-10-2018 Tharo_2248 26cc25f57b880e45d70ebf048e6c1dd9 403 Pfam PF13692 Glycosyl transferases group 1 211 349 2.4E-26 T 14-10-2018 Tharo_2248 26cc25f57b880e45d70ebf048e6c1dd9 403 Gene3D G3DSA:3.40.50.2000 34 379 2.3E-41 T 14-10-2018 Tharo_2248 26cc25f57b880e45d70ebf048e6c1dd9 403 SUPERFAMILY SSF53756 34 379 8.52E-60 T 14-10-2018 Tharo_2248 26cc25f57b880e45d70ebf048e6c1dd9 403 Gene3D G3DSA:3.40.50.2000 197 369 2.3E-41 T 14-10-2018 Tharo_0259 26997868e01fbc76f8ad68a256889e00 633 Pfam PF07730 Histidine kinase 416 481 1.4E-14 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Tharo_0259 26997868e01fbc76f8ad68a256889e00 633 Pfam PF00672 HAMP domain 200 248 5.2E-14 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_0259 26997868e01fbc76f8ad68a256889e00 633 PIRSF PIRSF003167 3 620 4.8E-167 T 14-10-2018 IPR016380 Signal transduction histidine kinase, nitrate/nitrite-sensing GO:0000155|GO:0000160|GO:0004673|GO:0016021 Tharo_0259 26997868e01fbc76f8ad68a256889e00 633 Gene3D G3DSA:3.30.565.10 483 614 1.8E-25 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_0259 26997868e01fbc76f8ad68a256889e00 633 SUPERFAMILY SSF158472 200 250 2.09E-10 T 14-10-2018 Tharo_0259 26997868e01fbc76f8ad68a256889e00 633 SMART SM00304 200 252 3.7E-14 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_0259 26997868e01fbc76f8ad68a256889e00 633 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 42 152 2.2E-6 T 14-10-2018 IPR029095 NarX-like, N-terminal Tharo_0259 26997868e01fbc76f8ad68a256889e00 633 Gene3D G3DSA:1.20.120.960 47 172 5.3E-6 T 14-10-2018 Tharo_0259 26997868e01fbc76f8ad68a256889e00 633 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 522 611 1.4E-5 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_0259 26997868e01fbc76f8ad68a256889e00 633 Gene3D G3DSA:1.10.287.130 198 309 9.9E-10 T 14-10-2018 Tharo_0259 26997868e01fbc76f8ad68a256889e00 633 SUPERFAMILY SSF55874 504 613 1.96E-15 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_0259 26997868e01fbc76f8ad68a256889e00 633 SMART SM00387 521 616 8.6E-8 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_3121 88d3336aa72f61607f1a4246d8f1726f 204 Pfam PF01323 DSBA-like thioredoxin domain 5 191 1.4E-33 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 Tharo_3121 88d3336aa72f61607f1a4246d8f1726f 204 PIRSF PIRSF006386 1 203 2.5E-52 T 14-10-2018 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590|Reactome: R-HSA-9033241 Tharo_3121 88d3336aa72f61607f1a4246d8f1726f 204 SUPERFAMILY SSF52833 5 197 9.51E-42 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_3121 88d3336aa72f61607f1a4246d8f1726f 204 Gene3D G3DSA:3.40.30.10 5 200 5.3E-59 T 14-10-2018 Tharo_0505 26cda3e3bb033994714eb76bbffa0bb0 466 Pfam PF00772 DnaB-like helicase N terminal domain 23 124 9.4E-36 T 14-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 Tharo_0505 26cda3e3bb033994714eb76bbffa0bb0 466 Gene3D G3DSA:3.40.50.300 181 462 3.5E-107 T 14-10-2018 Tharo_0505 26cda3e3bb033994714eb76bbffa0bb0 466 Gene3D G3DSA:1.10.860.10 16 180 2.2E-53 T 14-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal Tharo_0505 26cda3e3bb033994714eb76bbffa0bb0 466 SUPERFAMILY SSF48024 21 132 1.44E-37 T 14-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 Tharo_0505 26cda3e3bb033994714eb76bbffa0bb0 466 SUPERFAMILY SSF52540 201 452 2.51E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0505 26cda3e3bb033994714eb76bbffa0bb0 466 Pfam PF03796 DnaB-like helicase C terminal domain 203 458 7.4E-114 T 14-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 Tharo_0505 26cda3e3bb033994714eb76bbffa0bb0 466 SMART SM00382 220 418 6.4E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0505 26cda3e3bb033994714eb76bbffa0bb0 466 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 22 460 6.7E-179 T 14-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 Tharo_2261 afeb0cd5fae8f8a1a242282cde364037 204 Pfam PF02630 SCO1/SenC 52 135 1.5E-11 T 14-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_2261 afeb0cd5fae8f8a1a242282cde364037 204 Gene3D G3DSA:3.40.30.10 46 201 8.9E-37 T 14-10-2018 Tharo_2261 afeb0cd5fae8f8a1a242282cde364037 204 SUPERFAMILY SSF52833 46 190 3.61E-28 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_0164 2b43a5d29471dbca8623c6627c26498c 262 SUPERFAMILY SSF55781 92 260 2.68E-40 T 14-10-2018 Tharo_0164 2b43a5d29471dbca8623c6627c26498c 262 Pfam PF09339 IclR helix-turn-helix domain 23 69 2.2E-11 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Tharo_0164 2b43a5d29471dbca8623c6627c26498c 262 Gene3D G3DSA:1.10.10.10 19 82 2.5E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0164 2b43a5d29471dbca8623c6627c26498c 262 SMART SM00346 20 108 6.4E-12 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Tharo_0164 2b43a5d29471dbca8623c6627c26498c 262 Gene3D G3DSA:3.30.450.40 84 262 3.3E-45 T 14-10-2018 IPR029016 GAF-like domain superfamily Tharo_0164 2b43a5d29471dbca8623c6627c26498c 262 Pfam PF01614 Bacterial transcriptional regulator 135 248 2.4E-27 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal Tharo_0164 2b43a5d29471dbca8623c6627c26498c 262 SUPERFAMILY SSF46785 20 90 5.46E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1673 7114d3b32f3115498ddb29c0fad11b03 122 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 73 84 - T 14-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 Tharo_1673 7114d3b32f3115498ddb29c0fad11b03 122 Gene3D G3DSA:1.10.3830.10 6 122 5.7E-41 T 14-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 Tharo_1673 7114d3b32f3115498ddb29c0fad11b03 122 Pfam PF01219 Prokaryotic diacylglycerol kinase 20 120 4.5E-37 T 14-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 Tharo_0748 812f0c8586a868d0aea2bad34bab878a 188 SUPERFAMILY SSF55068 10 176 1.44E-69 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 Tharo_0748 812f0c8586a868d0aea2bad34bab878a 188 Pfam PF01625 Peptide methionine sulfoxide reductase 12 165 3.8E-59 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 Tharo_0748 812f0c8586a868d0aea2bad34bab878a 188 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 11 160 4.7E-51 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 Tharo_0748 812f0c8586a868d0aea2bad34bab878a 188 Gene3D G3DSA:3.30.1060.10 1 174 2.2E-64 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 Tharo_0748 812f0c8586a868d0aea2bad34bab878a 188 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 10 169 34.885 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 Tharo_0590 eeb70db13fbbca514107f658b32793ed 475 Gene3D G3DSA:1.10.510.10 19 319 6.5E-21 T 14-10-2018 Tharo_0590 eeb70db13fbbca514107f658b32793ed 475 Pfam PF00069 Protein kinase domain 134 234 1.2E-11 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Tharo_0590 eeb70db13fbbca514107f658b32793ed 475 SMART SM00220 23 307 1.8E-6 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Tharo_0590 eeb70db13fbbca514107f658b32793ed 475 SUPERFAMILY SSF56112 19 308 3.24E-23 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Tharo_3282 9372bda4648e88374fb561faf93647d4 380 Gene3D G3DSA:3.40.50.11750 27 266 6.6E-100 T 14-10-2018 Tharo_3282 9372bda4648e88374fb561faf93647d4 380 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 2 373 2.3E-135 T 14-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 Tharo_3282 9372bda4648e88374fb561faf93647d4 380 Gene3D G3DSA:3.40.50.11740 61 307 6.6E-100 T 14-10-2018 Tharo_3282 9372bda4648e88374fb561faf93647d4 380 PIRSF PIRSF005622 1 375 5.7E-149 T 14-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 Tharo_3282 9372bda4648e88374fb561faf93647d4 380 Pfam PF01924 Hydrogenase formation hypA family 13 370 7.7E-147 T 14-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 Tharo_3282 9372bda4648e88374fb561faf93647d4 380 Gene3D G3DSA:1.10.10.2140 321 372 3.0E-24 T 14-10-2018 Tharo_0413 b41b1d0d52908595ab3b78ea9bc60bed 220 Gene3D G3DSA:3.40.50.1820 4 218 2.6E-49 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_0413 b41b1d0d52908595ab3b78ea9bc60bed 220 SUPERFAMILY SSF53474 6 213 8.39E-38 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_0413 b41b1d0d52908595ab3b78ea9bc60bed 220 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 56 123 2.7E-9 T 14-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 Tharo_2604 2679f8871f3cccaf3e97f5106eca9e7d 102 Pfam PF01381 Helix-turn-helix 19 63 1.1E-6 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_2604 2679f8871f3cccaf3e97f5106eca9e7d 102 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 4 87 6.1E-29 T 14-10-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 Tharo_2604 2679f8871f3cccaf3e97f5106eca9e7d 102 SUPERFAMILY SSF47413 9 87 4.35E-19 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_2604 2679f8871f3cccaf3e97f5106eca9e7d 102 Gene3D G3DSA:1.10.260.40 2 87 1.6E-28 T 14-10-2018 Tharo_1087 b147c87b9a9b5a048b75178553fb1880 98 Gene3D G3DSA:1.10.260.40 2 88 1.9E-11 T 14-10-2018 Tharo_1087 b147c87b9a9b5a048b75178553fb1880 98 Pfam PF01381 Helix-turn-helix 10 47 4.1E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_1087 b147c87b9a9b5a048b75178553fb1880 98 SUPERFAMILY SSF47413 10 64 2.82E-8 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_0004 134fa3dc33b75566b7bc898dd94e1490 1022 SUPERFAMILY SSF52540 171 651 1.15E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0004 134fa3dc33b75566b7bc898dd94e1490 1022 Pfam PF04851 Type III restriction enzyme, res subunit 150 372 9.6E-11 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 Tharo_1883 e6a9fd5d75da20bce64c5ec879648d48 453 Pfam PF00069 Protein kinase domain 11 265 1.5E-51 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Tharo_1883 e6a9fd5d75da20bce64c5ec879648d48 453 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 136 148 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Tharo_1883 e6a9fd5d75da20bce64c5ec879648d48 453 PIRSF PIRSF000654 37 269 2.1E-25 T 14-10-2018 Tharo_1883 e6a9fd5d75da20bce64c5ec879648d48 453 Gene3D G3DSA:2.60.120.10 294 433 8.6E-15 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Tharo_1883 e6a9fd5d75da20bce64c5ec879648d48 453 Gene3D G3DSA:1.10.510.10 4 280 8.4E-68 T 14-10-2018 Tharo_1883 e6a9fd5d75da20bce64c5ec879648d48 453 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 Tharo_1883 e6a9fd5d75da20bce64c5ec879648d48 453 SUPERFAMILY SSF56112 4 273 2.97E-72 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Tharo_1883 e6a9fd5d75da20bce64c5ec879648d48 453 SUPERFAMILY SSF51206 296 406 3.59E-15 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like Tharo_1883 e6a9fd5d75da20bce64c5ec879648d48 453 SMART SM00220 11 276 4.5E-59 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Tharo_1883 e6a9fd5d75da20bce64c5ec879648d48 453 Pfam PF00027 Cyclic nucleotide-binding domain 322 398 7.7E-8 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain Tharo_0626 81dac5547c2ac5166fc07befff2422c6 283 PRINTS PR01805 VacJ lipoprotein signature 34 47 1.8E-25 T 14-10-2018 IPR007428 MlaA lipoprotein GO:0016020 Tharo_0626 81dac5547c2ac5166fc07befff2422c6 283 PRINTS PR01805 VacJ lipoprotein signature 51 67 1.8E-25 T 14-10-2018 IPR007428 MlaA lipoprotein GO:0016020 Tharo_0626 81dac5547c2ac5166fc07befff2422c6 283 PRINTS PR01805 VacJ lipoprotein signature 102 119 1.8E-25 T 14-10-2018 IPR007428 MlaA lipoprotein GO:0016020 Tharo_0626 81dac5547c2ac5166fc07befff2422c6 283 PRINTS PR01805 VacJ lipoprotein signature 138 155 1.8E-25 T 14-10-2018 IPR007428 MlaA lipoprotein GO:0016020 Tharo_0626 81dac5547c2ac5166fc07befff2422c6 283 Pfam PF04333 MlaA lipoprotein 34 225 1.9E-71 T 14-10-2018 IPR007428 MlaA lipoprotein GO:0016020 Tharo_2572 ed3f54db6e4f14fccaf3f6c7727c2d6a 141 SUPERFAMILY SSF53098 16 83 1.9E-12 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_2572 ed3f54db6e4f14fccaf3f6c7727c2d6a 141 Pfam PF13683 Integrase core domain 18 74 1.4E-11 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Tharo_0028 bf6ca97a3c799d9dda031a7d0f326e4f 299 SUPERFAMILY SSF102114 5 243 3.14E-31 T 14-10-2018 Tharo_0028 bf6ca97a3c799d9dda031a7d0f326e4f 299 Gene3D G3DSA:3.20.20.70 22 276 2.1E-13 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_0028 bf6ca97a3c799d9dda031a7d0f326e4f 299 Pfam PF04055 Radical SAM superfamily 27 184 1.0E-14 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_0028 bf6ca97a3c799d9dda031a7d0f326e4f 299 SMART SM00729 21 241 3.5E-21 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Tharo_1262 9b57e07a8bc749a1a1da20623366c551 163 SUPERFAMILY SSF117916 1 97 2.13E-23 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Tharo_1262 9b57e07a8bc749a1a1da20623366c551 163 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 14 163 2.9E-63 T 14-10-2018 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit Tharo_1262 9b57e07a8bc749a1a1da20623366c551 163 Pfam PF01883 Iron-sulfur cluster assembly protein 5 71 4.1E-14 T 14-10-2018 IPR002744 MIP18 family-like Tharo_1262 9b57e07a8bc749a1a1da20623366c551 163 Gene3D G3DSA:3.30.300.130 2 98 1.2E-24 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Tharo_0209 27bff67d9e8cc1e25f554a4d1b898f0b 138 Pfam PF10387 Protein of unknown function (DUF2442) 26 94 1.2E-9 T 14-10-2018 IPR018841 Protein of unknown function DUF2442 Tharo_0209 27bff67d9e8cc1e25f554a4d1b898f0b 138 Gene3D G3DSA:3.30.2020.20 9 105 7.2E-34 T 14-10-2018 Tharo_1009 00ad779831a04bcedaa9bc2ae8fc7713 117 Gene3D G3DSA:2.102.10.10 18 117 1.3E-24 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Tharo_1009 00ad779831a04bcedaa9bc2ae8fc7713 117 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 18 116 9.0E-26 T 14-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 Tharo_1009 00ad779831a04bcedaa9bc2ae8fc7713 117 Pfam PF13806 Rieske-like [2Fe-2S] domain 18 115 3.3E-14 T 14-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 Tharo_1009 00ad779831a04bcedaa9bc2ae8fc7713 117 SUPERFAMILY SSF50022 18 116 3.14E-30 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Tharo_3123 c73f3e7c50493db2f2b6f526870d1235 224 Pfam PF06295 Protein of unknown function (DUF1043) 11 100 1.2E-14 T 14-10-2018 IPR009386 Protein of unknown function DUF1043 Tharo_1202 8ebc151d9c4436e5aded651edf610288 374 SMART SM00271 4 62 1.9E-32 T 14-10-2018 IPR001623 DnaJ domain Tharo_1202 8ebc151d9c4436e5aded651edf610288 374 SUPERFAMILY SSF57938 133 210 1.57E-22 T 14-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily Tharo_1202 8ebc151d9c4436e5aded651edf610288 374 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 348 5.7E-139 T 14-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 Tharo_1202 8ebc151d9c4436e5aded651edf610288 374 PRINTS PR00625 DnaJ domain signature 7 25 1.2E-32 T 14-10-2018 IPR001623 DnaJ domain Tharo_1202 8ebc151d9c4436e5aded651edf610288 374 PRINTS PR00625 DnaJ domain signature 62 81 1.2E-32 T 14-10-2018 IPR001623 DnaJ domain Tharo_1202 8ebc151d9c4436e5aded651edf610288 374 PRINTS PR00625 DnaJ domain signature 25 40 1.2E-32 T 14-10-2018 IPR001623 DnaJ domain Tharo_1202 8ebc151d9c4436e5aded651edf610288 374 PRINTS PR00625 DnaJ domain signature 42 62 1.2E-32 T 14-10-2018 IPR001623 DnaJ domain Tharo_1202 8ebc151d9c4436e5aded651edf610288 374 Pfam PF01556 DnaJ C terminal domain 120 332 3.3E-43 T 14-10-2018 IPR002939 Chaperone DnaJ, C-terminal Tharo_1202 8ebc151d9c4436e5aded651edf610288 374 SUPERFAMILY SSF46565 1 109 1.31E-37 T 14-10-2018 IPR036869 Chaperone J-domain superfamily Tharo_1202 8ebc151d9c4436e5aded651edf610288 374 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 371 42.42 T 14-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 Tharo_1202 8ebc151d9c4436e5aded651edf610288 374 Pfam PF00684 DnaJ central domain 146 206 1.1E-14 T 14-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 Tharo_1202 8ebc151d9c4436e5aded651edf610288 374 SUPERFAMILY SSF49493 114 255 7.19E-20 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Tharo_1202 8ebc151d9c4436e5aded651edf610288 374 Gene3D G3DSA:2.10.230.10 144 210 3.1E-23 T 14-10-2018 Tharo_1202 8ebc151d9c4436e5aded651edf610288 374 SUPERFAMILY SSF49493 257 343 1.44E-21 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Tharo_1202 8ebc151d9c4436e5aded651edf610288 374 Gene3D G3DSA:1.10.287.110 1 113 6.9E-38 T 14-10-2018 IPR036869 Chaperone J-domain superfamily Tharo_1202 8ebc151d9c4436e5aded651edf610288 374 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 14-10-2018 IPR018253 DnaJ domain, conserved site Tharo_1202 8ebc151d9c4436e5aded651edf610288 374 Gene3D G3DSA:2.60.260.20 256 362 1.3E-27 T 14-10-2018 Tharo_1202 8ebc151d9c4436e5aded651edf610288 374 Pfam PF00226 DnaJ domain 5 67 1.2E-28 T 14-10-2018 IPR001623 DnaJ domain Tharo_2269 3ed429e15cb814cd6a15306e5f67c73e 177 Gene3D G3DSA:2.30.30.40 21 152 5.9E-40 T 14-10-2018 Tharo_2269 3ed429e15cb814cd6a15306e5f67c73e 177 Gene3D G3DSA:2.40.50.180 38 153 5.9E-40 T 14-10-2018 Tharo_2269 3ed429e15cb814cd6a15306e5f67c73e 177 Pfam PF01584 CheW-like domain 19 159 5.9E-37 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Tharo_2269 3ed429e15cb814cd6a15306e5f67c73e 177 SUPERFAMILY SSF50341 12 160 8.89E-39 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 Tharo_2269 3ed429e15cb814cd6a15306e5f67c73e 177 SMART SM00260 15 158 8.9E-34 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Tharo_2567 3ac272a8dc67ddb88f1cd9c817159604 192 SUPERFAMILY SSF101874 26 191 3.27E-53 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily Tharo_2567 3ac272a8dc67ddb88f1cd9c817159604 192 Gene3D G3DSA:2.40.128.110 26 192 3.3E-49 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily Tharo_2567 3ac272a8dc67ddb88f1cd9c817159604 192 Pfam PF04264 YceI-like domain 28 189 3.6E-39 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Tharo_2567 3ac272a8dc67ddb88f1cd9c817159604 192 SMART SM00867 27 190 4.4E-62 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Tharo_1076 413b94781e145972f246077512c37781 331 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 23 300 1.6E-88 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 Tharo_1076 413b94781e145972f246077512c37781 331 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 22 330 28.571 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 Tharo_1076 413b94781e145972f246077512c37781 331 Gene3D G3DSA:3.40.50.300 26 300 2.3E-94 T 14-10-2018 Tharo_1076 413b94781e145972f246077512c37781 331 SUPERFAMILY SSF52540 24 167 1.22E-17 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1076 413b94781e145972f246077512c37781 331 Gene3D G3DSA:1.10.20.140 129 201 2.3E-94 T 14-10-2018 Tharo_1076 413b94781e145972f246077512c37781 331 Pfam PF01715 IPP transferase 56 299 2.7E-82 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 Tharo_1412 f4562221be72e8fd1bbf9a25d5a5e57b 327 SUPERFAMILY SSF52922 190 323 8.51E-38 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Tharo_1412 f4562221be72e8fd1bbf9a25d5a5e57b 327 Gene3D G3DSA:3.40.50.920 198 324 7.7E-43 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Tharo_1412 f4562221be72e8fd1bbf9a25d5a5e57b 327 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 3.0E-50 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Tharo_1412 f4562221be72e8fd1bbf9a25d5a5e57b 327 Pfam PF02780 Transketolase, C-terminal domain 199 315 9.2E-35 T 14-10-2018 IPR033248 Transketolase, C-terminal domain Tharo_1412 f4562221be72e8fd1bbf9a25d5a5e57b 327 SUPERFAMILY SSF52518 4 192 3.37E-67 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_1412 f4562221be72e8fd1bbf9a25d5a5e57b 327 Gene3D G3DSA:3.40.50.970 2 192 2.4E-78 T 14-10-2018 Tharo_1412 f4562221be72e8fd1bbf9a25d5a5e57b 327 SMART SM00861 4 179 3.2E-66 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Tharo_3012 2d2b868c43b56e9039172019fe83a9fb 589 Pfam PF00563 EAL domain 336 571 4.0E-67 T 14-10-2018 IPR001633 EAL domain Tharo_3012 2d2b868c43b56e9039172019fe83a9fb 589 Gene3D G3DSA:3.20.20.450 332 583 3.6E-91 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_3012 2d2b868c43b56e9039172019fe83a9fb 589 SMART SM00052 330 576 2.0E-85 T 14-10-2018 IPR001633 EAL domain Tharo_3012 2d2b868c43b56e9039172019fe83a9fb 589 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 157 318 5.5E-41 T 14-10-2018 IPR000160 GGDEF domain Tharo_3012 2d2b868c43b56e9039172019fe83a9fb 589 SMART SM00267 146 320 1.2E-52 T 14-10-2018 IPR000160 GGDEF domain Tharo_3012 2d2b868c43b56e9039172019fe83a9fb 589 SUPERFAMILY SSF55073 163 322 3.69E-49 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_3012 2d2b868c43b56e9039172019fe83a9fb 589 SUPERFAMILY SSF141868 335 583 5.1E-81 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_3012 2d2b868c43b56e9039172019fe83a9fb 589 Gene3D G3DSA:3.30.70.270 160 329 5.0E-57 T 14-10-2018 Tharo_3012 2d2b868c43b56e9039172019fe83a9fb 589 Pfam PF00990 Diguanylate cyclase, GGDEF domain 158 314 9.3E-45 T 14-10-2018 IPR000160 GGDEF domain Tharo_1502 f0247704a6fec8873780a645fef68c8c 265 Pfam PF05742 Transport and Golgi organisation 2 1 249 1.3E-62 T 14-10-2018 IPR008551 Transport and Golgi organisation protein 2 Tharo_1502 f0247704a6fec8873780a645fef68c8c 265 Gene3D G3DSA:3.60.60.10 4 240 2.0E-5 T 14-10-2018 Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 SUPERFAMILY SSF141259 503 578 5.36E-23 T 14-10-2018 IPR036101 CarD-like/TRCF domain superfamily Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 Pfam PF02559 CarD-like/TRCF domain 510 605 2.5E-25 T 14-10-2018 IPR003711 CarD-like/TRCF domain Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 SMART SM01058 509 606 8.0E-47 T 14-10-2018 IPR003711 CarD-like/TRCF domain Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 SUPERFAMILY SSF52540 813 1020 1.77E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 SUPERFAMILY SSF143517 1025 1173 8.24E-38 T 14-10-2018 IPR037235 TRCF-like, C-terminal domain Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 Pfam PF03461 TRCF domain 1039 1131 2.9E-27 T 14-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 Pfam PF00270 DEAD/DEAH box helicase 635 792 6.2E-19 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 SMART SM00490 856 940 1.3E-17 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 Gene3D G3DSA:3.40.50.300 572 811 1.9E-227 T 14-10-2018 Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 Gene3D G3DSA:2.30.30.840 513 571 1.9E-227 T 14-10-2018 Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 Gene3D G3DSA:3.90.1150.50 1035 1176 3.4E-38 T 14-10-2018 IPR037235 TRCF-like, C-terminal domain Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 Gene3D G3DSA:3.30.2060.10 135 220 6.2E-112 T 14-10-2018 Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 155 1111 0.0 T 14-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 Gene3D G3DSA:3.40.50.300 508 1019 1.9E-227 T 14-10-2018 Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 SUPERFAMILY SSF52540 553 813 4.93E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 SUPERFAMILY SSF52540 383 495 1.7E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 SUPERFAMILY SSF52540 20 345 2.42E-97 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 SMART SM00982 1038 1138 1.8E-44 T 14-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 Pfam PF00271 Helicase conserved C-terminal domain 837 939 1.8E-16 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 SMART SM00487 630 820 2.5E-36 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 39 1157 27.038 T 14-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 Gene3D G3DSA:3.40.50.11140 382 482 1.6E-9 T 14-10-2018 Tharo_1948 c14f005bdbd05400e0c65a1af3a9c3cb 1176 Gene3D G3DSA:3.40.50.11180 31 338 6.2E-112 T 14-10-2018 Tharo_0194 5bbe856dae64d8a376d59d5db2f1bdb7 823 Hamap MF_01612 FO synthase subunit 2 [cofH]. 423 786 47.853 T 14-10-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77 Tharo_0194 5bbe856dae64d8a376d59d5db2f1bdb7 823 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 471 782 9.0E-113 T 14-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 Tharo_0194 5bbe856dae64d8a376d59d5db2f1bdb7 823 Gene3D G3DSA:3.20.20.70 420 784 2.2E-54 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_0194 5bbe856dae64d8a376d59d5db2f1bdb7 823 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 437 784 6.2E-149 T 14-10-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77 Tharo_0194 5bbe856dae64d8a376d59d5db2f1bdb7 823 Hamap MF_01611 FO synthase subunit 1 [cofG]. 57 383 46.893 T 14-10-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77 Tharo_0194 5bbe856dae64d8a376d59d5db2f1bdb7 823 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 58 381 3.8E-133 T 14-10-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77 Tharo_0194 5bbe856dae64d8a376d59d5db2f1bdb7 823 SUPERFAMILY SSF102114 23 357 2.26E-43 T 14-10-2018 Tharo_0194 5bbe856dae64d8a376d59d5db2f1bdb7 823 SUPERFAMILY SSF102114 435 777 3.27E-50 T 14-10-2018 Tharo_0194 5bbe856dae64d8a376d59d5db2f1bdb7 823 Pfam PF04055 Radical SAM superfamily 65 241 2.1E-11 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_0194 5bbe856dae64d8a376d59d5db2f1bdb7 823 SMART SM00729 61 288 4.7E-9 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Tharo_0194 5bbe856dae64d8a376d59d5db2f1bdb7 823 Pfam PF04055 Radical SAM superfamily 480 645 1.2E-15 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_0194 5bbe856dae64d8a376d59d5db2f1bdb7 823 Gene3D G3DSA:3.20.20.70 3 317 4.2E-57 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_1926 41cb94cd737b1936562fbdd1eeed021c 493 Pfam PF00361 Proton-conducting membrane transporter 134 419 4.3E-77 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1926 41cb94cd737b1936562fbdd1eeed021c 493 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 7 487 4.0E-190 T 14-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1926 41cb94cd737b1936562fbdd1eeed021c 493 Pfam PF01059 NADH-ubiquinone oxidoreductase chain 4, amino terminus 59 126 2.0E-5 T 14-10-2018 IPR000260 NADH:ubiquinone oxidoreductase chain 4, N-terminal GO:0006120|GO:0055114 KEGG: 00190+1.6.5.3|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-5083|MetaCyc: PWY-6692|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1926 41cb94cd737b1936562fbdd1eeed021c 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 138 157 1.0E-48 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1926 41cb94cd737b1936562fbdd1eeed021c 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 168 192 1.0E-48 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1926 41cb94cd737b1936562fbdd1eeed021c 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 378 404 1.0E-48 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1926 41cb94cd737b1936562fbdd1eeed021c 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 326 345 1.0E-48 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1926 41cb94cd737b1936562fbdd1eeed021c 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 238 262 1.0E-48 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1071 590afcaa9768121d34b11f6c8b9ebafc 396 Pfam PF01966 HD domain 207 328 4.6E-18 T 14-10-2018 IPR006674 HD domain Tharo_1071 590afcaa9768121d34b11f6c8b9ebafc 396 SMART SM00448 38 152 3.5E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1071 590afcaa9768121d34b11f6c8b9ebafc 396 Gene3D G3DSA:3.40.50.2300 28 172 1.9E-34 T 14-10-2018 Tharo_1071 590afcaa9768121d34b11f6c8b9ebafc 396 Pfam PF00072 Response regulator receiver domain 40 150 3.2E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1071 590afcaa9768121d34b11f6c8b9ebafc 396 SUPERFAMILY SSF52172 36 178 2.13E-35 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1071 590afcaa9768121d34b11f6c8b9ebafc 396 Gene3D G3DSA:1.10.3210.10 179 382 1.6E-74 T 14-10-2018 Tharo_1071 590afcaa9768121d34b11f6c8b9ebafc 396 SUPERFAMILY SSF109604 187 369 8.48E-41 T 14-10-2018 Tharo_1071 590afcaa9768121d34b11f6c8b9ebafc 396 SMART SM00471 201 338 4.5E-9 T 14-10-2018 IPR003607 HD/PDEase domain Tharo_2938 e2752cb989177ecf09e1a490fec6a881 384 Gene3D G3DSA:3.30.1540.10 216 304 3.5E-110 T 14-10-2018 Tharo_2938 e2752cb989177ecf09e1a490fec6a881 384 SUPERFAMILY SSF89796 2 373 1.83E-108 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily Tharo_2938 e2752cb989177ecf09e1a490fec6a881 384 Gene3D G3DSA:3.40.50.10540 2 322 3.5E-110 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily Tharo_2938 e2752cb989177ecf09e1a490fec6a881 384 Pfam PF02515 CoA-transferase family III 2 354 4.7E-82 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 Tharo_1060 18d907f7a123d8410c3d057917301f76 85 SMART SM00834 1 42 4.4E-19 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain Tharo_1060 18d907f7a123d8410c3d057917301f76 85 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 52 5.7E-23 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain Tharo_1060 18d907f7a123d8410c3d057917301f76 85 Pfam PF09723 Zinc ribbon domain 1 39 1.1E-15 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain Tharo_2144 eb179231271e1a1f663ab30647562c93 418 Pfam PF04381 Putative exonuclease, RdgC 2 293 3.9E-91 T 14-10-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 Tharo_2144 eb179231271e1a1f663ab30647562c93 418 Gene3D G3DSA:1.10.10.10 353 416 1.9E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2144 eb179231271e1a1f663ab30647562c93 418 Pfam PF09397 Ftsk gamma domain 357 417 8.7E-25 T 14-10-2018 IPR018541 FtsK gamma domain Tharo_2144 eb179231271e1a1f663ab30647562c93 418 SUPERFAMILY SSF46785 356 417 4.76E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_2144 eb179231271e1a1f663ab30647562c93 418 SMART SM00843 355 418 3.6E-30 T 14-10-2018 IPR018541 FtsK gamma domain Tharo_2213 65a471e12144b5f4be46e8efd394fa0e 191 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 159 165 - T 14-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 Tharo_2213 65a471e12144b5f4be46e8efd394fa0e 191 Gene3D G3DSA:3.30.160.70 16 107 6.4E-30 T 14-10-2018 Tharo_2213 65a471e12144b5f4be46e8efd394fa0e 191 SUPERFAMILY SSF53155 29 106 9.02E-21 T 14-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 Tharo_2213 65a471e12144b5f4be46e8efd394fa0e 191 Gene3D G3DSA:1.10.10.10 108 191 1.4E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2213 65a471e12144b5f4be46e8efd394fa0e 191 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 35 95 1.4E-5 T 14-10-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 Tharo_2213 65a471e12144b5f4be46e8efd394fa0e 191 SUPERFAMILY SSF46767 108 188 6.8E-30 T 14-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 Tharo_2213 65a471e12144b5f4be46e8efd394fa0e 191 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 109 188 7.0E-34 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 Tharo_2213 65a471e12144b5f4be46e8efd394fa0e 191 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 110 188 8.3E-32 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 Tharo_3402 0e3cbfb2adbe579f2f2ff1c87b6122ac 69 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 5.0E-21 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor Tharo_3402 0e3cbfb2adbe579f2f2ff1c87b6122ac 69 Pfam PF01809 Haemolytic domain 3 68 1.0E-30 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor Tharo_3402 0e3cbfb2adbe579f2f2ff1c87b6122ac 69 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 6 69 3.7E-28 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor Tharo_3402 0e3cbfb2adbe579f2f2ff1c87b6122ac 69 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 25.138 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor Tharo_3402 0e3cbfb2adbe579f2f2ff1c87b6122ac 69 SMART SM01234 1 68 9.3E-48 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor Tharo_2607 5ba2fa6dca0446e794891c813ecc9762 284 Pfam PF01163 RIO1 family 31 220 2.2E-44 T 14-10-2018 Tharo_2607 5ba2fa6dca0446e794891c813ecc9762 284 Gene3D G3DSA:3.30.200.20 17 126 6.4E-5 T 14-10-2018 Tharo_2607 5ba2fa6dca0446e794891c813ecc9762 284 SUPERFAMILY SSF56112 20 213 2.53E-21 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Tharo_2607 5ba2fa6dca0446e794891c813ecc9762 284 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 164 175 - T 14-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 Tharo_2607 5ba2fa6dca0446e794891c813ecc9762 284 Gene3D G3DSA:1.10.510.10 139 224 2.0E-19 T 14-10-2018 Tharo_2607 5ba2fa6dca0446e794891c813ecc9762 284 SMART SM00090 5 234 3.9E-18 T 14-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 Tharo_3216 c8269b28f30bf44ea13bb5610ef982ca 470 SUPERFAMILY SSF52540 19 204 2.38E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3216 c8269b28f30bf44ea13bb5610ef982ca 470 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 21 195 1.5E-13 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain Tharo_3216 c8269b28f30bf44ea13bb5610ef982ca 470 SUPERFAMILY SSF52317 249 439 2.59E-27 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Tharo_3216 c8269b28f30bf44ea13bb5610ef982ca 470 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 250 431 3.5E-28 T 14-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 Tharo_3216 c8269b28f30bf44ea13bb5610ef982ca 470 Gene3D G3DSA:3.40.50.300 57 193 6.9E-13 T 14-10-2018 Tharo_3216 c8269b28f30bf44ea13bb5610ef982ca 470 Gene3D G3DSA:3.40.50.880 259 397 2.0E-6 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Tharo_1510 ff574d8eb596ea2589895f856719640c 568 SUPERFAMILY SSF52091 451 559 4.32E-15 T 14-10-2018 IPR036513 STAS domain superfamily Tharo_1510 ff574d8eb596ea2589895f856719640c 568 Pfam PF01740 STAS domain 452 554 4.7E-13 T 14-10-2018 IPR002645 STAS domain Tharo_1510 ff574d8eb596ea2589895f856719640c 568 Gene3D G3DSA:3.30.750.24 437 564 1.1E-20 T 14-10-2018 IPR036513 STAS domain superfamily Tharo_1510 ff574d8eb596ea2589895f856719640c 568 Pfam PF00916 Sulfate permease family 27 393 3.4E-86 T 14-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 Tharo_1510 ff574d8eb596ea2589895f856719640c 568 TIGRFAM TIGR00815 sulP: sulfate permease 13 542 2.1E-114 T 14-10-2018 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Tharo_3231 6bb34d106528ea56ab26e2a2f1416b1a 75 SUPERFAMILY SSF47598 2 42 9.64E-9 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Tharo_3231 6bb34d106528ea56ab26e2a2f1416b1a 75 Pfam PF01402 Ribbon-helix-helix protein, copG family 3 39 1.7E-4 T 14-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 Tharo_0219 21552ff1b45af57985eb3ef1d73e3c19 133 Gene3D G3DSA:3.40.50.1010 1 132 6.6E-38 T 14-10-2018 Tharo_0219 21552ff1b45af57985eb3ef1d73e3c19 133 Pfam PF01850 PIN domain 2 117 5.4E-17 T 14-10-2018 IPR002716 PIN domain Tharo_0219 21552ff1b45af57985eb3ef1d73e3c19 133 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 131 9.759 T 14-10-2018 IPR022907 VapC family GO:0004540 Tharo_0219 21552ff1b45af57985eb3ef1d73e3c19 133 SUPERFAMILY SSF88723 1 132 5.05E-27 T 14-10-2018 IPR029060 PIN-like domain superfamily Tharo_0664 e9d89202723eaa0a27aa89a93644609c 749 Gene3D G3DSA:3.40.50.970 381 595 4.1E-45 T 14-10-2018 Tharo_0664 e9d89202723eaa0a27aa89a93644609c 749 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 394 563 2.3E-39 T 14-10-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 Tharo_0664 e9d89202723eaa0a27aa89a93644609c 749 SUPERFAMILY SSF52518 372 580 7.06E-6 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_0664 e9d89202723eaa0a27aa89a93644609c 749 Gene3D G3DSA:3.40.50.970 10 380 4.5E-57 T 14-10-2018 Tharo_0664 e9d89202723eaa0a27aa89a93644609c 749 Pfam PF09364 XFP N-terminal domain 37 323 4.6E-11 T 14-10-2018 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal Tharo_0664 e9d89202723eaa0a27aa89a93644609c 749 SUPERFAMILY SSF52518 42 341 1.84E-19 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold Tharo_3344 6978480507db63aa1ec8b5787e0cacfc 88 Pfam PF13470 PIN domain 6 62 2.4E-9 T 14-10-2018 IPR002716 PIN domain Tharo_3053 558e61009de5716d039d3afaf29518e1 406 PIRSF PIRSF016719 2 406 1.1E-102 T 14-10-2018 IPR008302 Uncharacterised conserved protein UCP016719 Tharo_3053 558e61009de5716d039d3afaf29518e1 406 Pfam PF07075 Protein of unknown function (DUF1343) 27 405 4.9E-110 T 14-10-2018 IPR008302 Uncharacterised conserved protein UCP016719 Tharo_3053 558e61009de5716d039d3afaf29518e1 406 Gene3D G3DSA:3.90.1150.140 226 390 4.4E-105 T 14-10-2018 Tharo_3053 558e61009de5716d039d3afaf29518e1 406 Gene3D G3DSA:3.40.50.12170 9 405 4.4E-105 T 14-10-2018 Tharo_2839 b9f46f9ecf7f471bd946150aa520e679 138 Gene3D G3DSA:3.30.420.270 63 132 4.8E-12 T 14-10-2018 Tharo_2839 b9f46f9ecf7f471bd946150aa520e679 138 Pfam PF02472 Biopolymer transport protein ExbD/TolR 15 136 1.6E-31 T 14-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 Tharo_3414 4259b77965b92bc933ae9e3d66466d4c 297 TIGRFAM TIGR02775 TrbG_Ti: P-type conjugative transfer protein TrbG 68 283 5.3E-93 T 14-10-2018 IPR014142 P-type conjugative transfer protein TrbG Tharo_3414 4259b77965b92bc933ae9e3d66466d4c 297 Pfam PF03524 Conjugal transfer protein 80 295 5.7E-58 T 14-10-2018 IPR010258 Conjugal transfer, TrbG/VirB9/CagX Tharo_3414 4259b77965b92bc933ae9e3d66466d4c 297 Gene3D G3DSA:2.60.40.2500 190 297 1.3E-7 T 14-10-2018 IPR038161 VirB9/CagX/TrbG, C-terminal domain superfamily Tharo_1416 7772ec6e580123478e6fe272a8975ca6 365 PIRSF PIRSF015283 1 346 1.1E-91 T 14-10-2018 IPR016631 Regulatory, RpfE Tharo_1416 7772ec6e580123478e6fe272a8975ca6 365 Gene3D G3DSA:3.30.70.2130 99 222 2.2E-7 T 14-10-2018 Tharo_2216 4963b2da15e911de76e0012fb3af5d4d 106 SUPERFAMILY SSF46626 12 103 1.72E-17 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_2216 4963b2da15e911de76e0012fb3af5d4d 106 Pfam PF00034 Cytochrome c 36 101 3.4E-4 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_2216 4963b2da15e911de76e0012fb3af5d4d 106 Gene3D G3DSA:1.10.760.10 29 104 1.8E-19 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_1190 70bc131aa18c0d699071900f5d8385b0 273 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 14-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Tharo_1190 70bc131aa18c0d699071900f5d8385b0 273 SUPERFAMILY SSF51366 1 258 3.11E-89 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Tharo_1190 70bc131aa18c0d699071900f5d8385b0 273 Gene3D G3DSA:3.20.20.70 1 268 1.7E-97 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_1190 70bc131aa18c0d699071900f5d8385b0 273 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 253 5.8E-73 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Tharo_1190 70bc131aa18c0d699071900f5d8385b0 273 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 261 33.886 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Tharo_1190 70bc131aa18c0d699071900f5d8385b0 273 Pfam PF00290 Tryptophan synthase alpha chain 8 254 2.7E-85 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Tharo_0303 60aa82f3c1e8007ef844856ca560977c 128 TIGRFAM TIGR03751 conj_TIGR03751: conjugative transfer region lipoprotein, TIGR03751 family 1 124 6.3E-53 T 14-10-2018 IPR022262 Lipoprotein, putative Tharo_3341 7350cbca98f09daed3a2890b2a17b271 413 SUPERFAMILY SSF103473 2 402 4.32E-32 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_3341 7350cbca98f09daed3a2890b2a17b271 413 Pfam PF07690 Major Facilitator Superfamily 5 360 4.1E-19 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_3341 7350cbca98f09daed3a2890b2a17b271 413 TIGRFAM TIGR00901 2A0125: AmpG-like permease 12 358 6.1E-112 T 14-10-2018 Tharo_3341 7350cbca98f09daed3a2890b2a17b271 413 Gene3D G3DSA:1.20.1250.20 1 398 2.2E-25 T 14-10-2018 Tharo_1817 4547bf46d4f426dc8be02ef4990d8148 238 Pfam PF00005 ABC transporter 24 166 4.7E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_1817 4547bf46d4f426dc8be02ef4990d8148 238 Gene3D G3DSA:3.40.50.300 4 238 2.1E-57 T 14-10-2018 Tharo_1817 4547bf46d4f426dc8be02ef4990d8148 238 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_1817 4547bf46d4f426dc8be02ef4990d8148 238 SMART SM00382 31 215 7.7E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1817 4547bf46d4f426dc8be02ef4990d8148 238 SUPERFAMILY SSF52540 11 234 3.04E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1663 941c3f370c495f6612957601e1525bbb 407 Pfam PF11741 AMIN domain 16 119 7.6E-23 T 14-10-2018 IPR021731 AMIN domain Tharo_1663 941c3f370c495f6612957601e1525bbb 407 SUPERFAMILY SSF53187 172 393 4.39E-56 T 14-10-2018 Tharo_1663 941c3f370c495f6612957601e1525bbb 407 SMART SM00646 234 389 7.4E-60 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 Tharo_1663 941c3f370c495f6612957601e1525bbb 407 Gene3D G3DSA:2.60.40.3500 3 121 1.5E-30 T 14-10-2018 Tharo_1663 941c3f370c495f6612957601e1525bbb 407 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 174 389 2.0E-49 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 Tharo_1663 941c3f370c495f6612957601e1525bbb 407 Gene3D G3DSA:3.40.630.40 161 400 4.1E-81 T 14-10-2018 Tharo_2223 f0c2a1471ddd648c2c5cf7efc8125b73 321 SUPERFAMILY SSF54292 213 319 5.9E-32 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Tharo_2223 f0c2a1471ddd648c2c5cf7efc8125b73 321 Gene3D G3DSA:3.10.20.30 225 321 6.8E-28 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Tharo_2223 f0c2a1471ddd648c2c5cf7efc8125b73 321 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 270 278 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Tharo_2223 f0c2a1471ddd648c2c5cf7efc8125b73 321 Gene3D G3DSA:3.40.50.80 102 223 1.4E-26 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_2223 f0c2a1471ddd648c2c5cf7efc8125b73 321 Gene3D G3DSA:2.40.30.10 2 101 2.1E-32 T 14-10-2018 Tharo_2223 f0c2a1471ddd648c2c5cf7efc8125b73 321 SUPERFAMILY SSF52343 106 224 4.19E-28 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Tharo_2223 f0c2a1471ddd648c2c5cf7efc8125b73 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 90 104 4.0E-56 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Tharo_2223 f0c2a1471ddd648c2c5cf7efc8125b73 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 112 131 4.0E-56 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Tharo_2223 f0c2a1471ddd648c2c5cf7efc8125b73 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 191 199 4.0E-56 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Tharo_2223 f0c2a1471ddd648c2c5cf7efc8125b73 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 40 52 4.0E-56 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Tharo_2223 f0c2a1471ddd648c2c5cf7efc8125b73 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 52 66 4.0E-56 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Tharo_2223 f0c2a1471ddd648c2c5cf7efc8125b73 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 30 40 4.0E-56 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Tharo_2223 f0c2a1471ddd648c2c5cf7efc8125b73 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 76 90 4.0E-56 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Tharo_2223 f0c2a1471ddd648c2c5cf7efc8125b73 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 137 146 4.0E-56 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Tharo_2223 f0c2a1471ddd648c2c5cf7efc8125b73 321 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 242 312 2.6E-14 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Tharo_2223 f0c2a1471ddd648c2c5cf7efc8125b73 321 SUPERFAMILY SSF63380 3 100 3.4E-29 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Tharo_1996 db5b71f3f5dc23b47383df608e9cd300 89 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 37 66 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 Tharo_1996 db5b71f3f5dc23b47383df608e9cd300 89 Gene3D G3DSA:2.40.50.100 6 89 2.1E-16 T 14-10-2018 Tharo_1996 db5b71f3f5dc23b47383df608e9cd300 89 Pfam PF00364 Biotin-requiring enzyme 29 86 1.5E-13 T 14-10-2018 IPR000089 Biotin/lipoyl attachment Tharo_1996 db5b71f3f5dc23b47383df608e9cd300 89 SUPERFAMILY SSF51230 27 88 4.11E-16 T 14-10-2018 IPR011053 Single hybrid motif Tharo_1730 0374d5c6017e7fe12a9268a6a4d446f7 234 Pfam PF02665 Nitrate reductase gamma subunit 5 226 7.4E-79 T 14-10-2018 IPR023234 NarG-like domain Tharo_1730 0374d5c6017e7fe12a9268a6a4d446f7 234 Gene3D G3DSA:1.20.950.20 2 218 3.7E-72 T 14-10-2018 Tharo_1730 0374d5c6017e7fe12a9268a6a4d446f7 234 SUPERFAMILY SSF103501 5 226 7.19E-63 T 14-10-2018 IPR036197 NarG-like superfamily Tharo_1730 0374d5c6017e7fe12a9268a6a4d446f7 234 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 4 226 6.6E-71 T 14-10-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 Tharo_2372 f1a6fb298c34b1aebb7bd5bd565819ca 220 Pfam PF01794 Ferric reductase like transmembrane component 48 161 4.8E-16 T 14-10-2018 IPR013130 Ferric reductase transmembrane component-like domain Tharo_2372 f1a6fb298c34b1aebb7bd5bd565819ca 220 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 5 200 21.996 T 14-10-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 Tharo_3030 466cd4dec79a2b83b8e3181f74754f3a 269 Gene3D G3DSA:3.30.70.270 93 268 5.5E-50 T 14-10-2018 Tharo_3030 466cd4dec79a2b83b8e3181f74754f3a 269 SUPERFAMILY SSF55073 113 267 5.89E-43 T 14-10-2018 IPR029787 Nucleotide cyclase Tharo_3030 466cd4dec79a2b83b8e3181f74754f3a 269 Pfam PF00990 Diguanylate cyclase, GGDEF domain 109 265 1.2E-39 T 14-10-2018 IPR000160 GGDEF domain Tharo_3030 466cd4dec79a2b83b8e3181f74754f3a 269 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 105 267 5.4E-44 T 14-10-2018 IPR000160 GGDEF domain Tharo_3030 466cd4dec79a2b83b8e3181f74754f3a 269 SMART SM00267 97 269 2.9E-51 T 14-10-2018 IPR000160 GGDEF domain Tharo_1243 5a59d7eb6a5cc42107da5a5e302aa70d 550 Gene3D G3DSA:3.40.920.10 26 230 6.5E-9 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Tharo_1243 5a59d7eb6a5cc42107da5a5e302aa70d 550 SUPERFAMILY SSF53323 29 229 1.16E-7 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Tharo_1243 5a59d7eb6a5cc42107da5a5e302aa70d 550 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 37 220 1.8E-12 T 14-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 Tharo_0625 6a4d1a7f1d93a5e29a9ad578708b31f6 158 Pfam PF02470 MlaD protein 39 117 3.4E-20 T 14-10-2018 IPR003399 Mce/MlaD Tharo_0625 6a4d1a7f1d93a5e29a9ad578708b31f6 158 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 5 147 3.3E-55 T 14-10-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 Tharo_0119 6eb6e16fbf3bf3512763299ba7ff43f1 193 Pfam PF02036 SCP-2 sterol transfer family 11 102 1.8E-5 T 14-10-2018 IPR003033 SCP2 sterol-binding domain Tharo_3110 29254b568fca1736ae61ef932c4a6239 297 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 8 296 2.9E-103 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Tharo_3110 29254b568fca1736ae61ef932c4a6239 297 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 4 296 46.845 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Tharo_3110 29254b568fca1736ae61ef932c4a6239 297 PIRSF PIRSF036480 4 297 3.4E-109 T 14-10-2018 Tharo_3110 29254b568fca1736ae61ef932c4a6239 297 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 124 151 7.4E-55 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Tharo_3110 29254b568fca1736ae61ef932c4a6239 297 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 9 35 7.4E-55 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Tharo_3110 29254b568fca1736ae61ef932c4a6239 297 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 248 270 7.4E-55 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Tharo_3110 29254b568fca1736ae61ef932c4a6239 297 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 102 124 7.4E-55 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Tharo_3110 29254b568fca1736ae61ef932c4a6239 297 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 270 295 7.4E-55 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Tharo_3110 29254b568fca1736ae61ef932c4a6239 297 Gene3D G3DSA:3.30.70.260 4 100 3.5E-23 T 14-10-2018 Tharo_3110 29254b568fca1736ae61ef932c4a6239 297 SUPERFAMILY SSF53328 101 297 8.11E-61 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Tharo_3110 29254b568fca1736ae61ef932c4a6239 297 SUPERFAMILY SSF55021 6 97 1.17E-14 T 14-10-2018 Tharo_3110 29254b568fca1736ae61ef932c4a6239 297 Gene3D G3DSA:3.40.50.170 101 297 2.0E-73 T 14-10-2018 Tharo_3110 29254b568fca1736ae61ef932c4a6239 297 Pfam PF00551 Formyl transferase 101 276 1.5E-38 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Tharo_2985 ecdf663d2d379b44a1b616647daf7261 141 Pfam PF07769 psiF repeat 25 57 6.9E-19 T 14-10-2018 IPR011690 Phosphate-starvation-induced PsiF repeat Tharo_2985 ecdf663d2d379b44a1b616647daf7261 141 Pfam PF07769 psiF repeat 115 140 2.9E-10 T 14-10-2018 IPR011690 Phosphate-starvation-induced PsiF repeat Tharo_2492 d2bd325300645ecc15cd1f88b45a0d80 220 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 3 203 7.3E-34 T 14-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like Tharo_2492 d2bd325300645ecc15cd1f88b45a0d80 220 Pfam PF12710 haloacid dehalogenase-like hydrolase 4 191 1.2E-32 T 14-10-2018 Tharo_2492 d2bd325300645ecc15cd1f88b45a0d80 220 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 3 193 2.9E-18 T 14-10-2018 Tharo_2492 d2bd325300645ecc15cd1f88b45a0d80 220 Gene3D G3DSA:3.40.50.1000 4 217 4.5E-70 T 14-10-2018 IPR023214 HAD superfamily Tharo_2492 d2bd325300645ecc15cd1f88b45a0d80 220 Gene3D G3DSA:1.20.1440.100 15 88 4.5E-70 T 14-10-2018 Tharo_2492 d2bd325300645ecc15cd1f88b45a0d80 220 SUPERFAMILY SSF56784 3 212 1.65E-27 T 14-10-2018 IPR036412 HAD-like superfamily Tharo_2219 93aa652f5b8896dcb77ca80783943b42 164 ProSitePatterns PS01117 MarR-type HTH domain signature. 73 107 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site Tharo_2219 93aa652f5b8896dcb77ca80783943b42 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 7.5E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_2219 93aa652f5b8896dcb77ca80783943b42 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 7.5E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_2219 93aa652f5b8896dcb77ca80783943b42 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 7.5E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_2219 93aa652f5b8896dcb77ca80783943b42 164 Pfam PF12802 MarR family 39 97 1.0E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_2219 93aa652f5b8896dcb77ca80783943b42 164 SUPERFAMILY SSF46785 14 153 5.62E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_2219 93aa652f5b8896dcb77ca80783943b42 164 Gene3D G3DSA:1.10.10.10 6 150 2.1E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2219 93aa652f5b8896dcb77ca80783943b42 164 SMART SM00347 34 134 8.1E-15 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Tharo_2564 6b1a557c02c9dbe5dd30141a7ee1266d 68 Gene3D G3DSA:3.40.50.10930 9 52 4.5E-8 T 14-10-2018 Tharo_2564 6b1a557c02c9dbe5dd30141a7ee1266d 68 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 10 48 1.1E-5 T 14-10-2018 Tharo_2609 ff014b136a4d3732f16eb6059404bac7 372 PIRSF PIRSF003109 12 371 6.5E-147 T 14-10-2018 IPR014407 5-methylcytosine restriction system component, bacterial GO:0009307 Tharo_2609 ff014b136a4d3732f16eb6059404bac7 372 Pfam PF10117 McrBC 5-methylcytosine restriction system component 25 310 6.5E-20 T 14-10-2018 IPR019292 5-methylcytosine restriction system component Tharo_2795 e88f4c9ce442b60d9e84c21164050cac 722 SUPERFAMILY SSF51703 9 551 2.94E-227 T 14-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Tharo_2795 e88f4c9ce442b60d9e84c21164050cac 722 Gene3D G3DSA:3.40.50.280 573 721 4.2E-49 T 14-10-2018 Tharo_2795 e88f4c9ce442b60d9e84c21164050cac 722 Pfam PF01642 Methylmalonyl-CoA mutase 37 549 1.5E-241 T 14-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Tharo_2795 e88f4c9ce442b60d9e84c21164050cac 722 Gene3D G3DSA:3.20.20.240 9 568 4.3E-245 T 14-10-2018 Tharo_2795 e88f4c9ce442b60d9e84c21164050cac 722 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 378 403 - T 14-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Tharo_2795 e88f4c9ce442b60d9e84c21164050cac 722 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 588 717 1.1E-57 T 14-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Tharo_2795 e88f4c9ce442b60d9e84c21164050cac 722 Pfam PF02310 B12 binding domain 591 701 5.6E-14 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 Tharo_2795 e88f4c9ce442b60d9e84c21164050cac 722 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 35 556 7.0E-271 T 14-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Tharo_2795 e88f4c9ce442b60d9e84c21164050cac 722 SUPERFAMILY SSF52242 557 715 2.22E-56 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 Tharo_1826 a120c4d4af600ff5a4c116a618d17e37 437 Pfam PF13458 Periplasmic binding protein 36 394 4.6E-46 T 14-10-2018 IPR028081 Leucine-binding protein domain Tharo_1826 a120c4d4af600ff5a4c116a618d17e37 437 SUPERFAMILY SSF53822 36 419 3.53E-57 T 14-10-2018 IPR028082 Periplasmic binding protein-like I Tharo_1826 a120c4d4af600ff5a4c116a618d17e37 437 Gene3D G3DSA:3.40.50.2300 164 394 4.5E-89 T 14-10-2018 Tharo_1826 a120c4d4af600ff5a4c116a618d17e37 437 Gene3D G3DSA:3.40.50.2300 57 386 4.5E-89 T 14-10-2018 Tharo_1995 056b396e459d868fc5c202ff4c71ab60 428 Pfam PF02308 MgtC family 20 137 1.9E-20 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 Tharo_1995 056b396e459d868fc5c202ff4c71ab60 428 Pfam PF13194 Domain of unknown function (DUF4010) 186 395 7.0E-59 T 14-10-2018 IPR025105 Domain of unknown function DUF4010 Tharo_1954 f039cd0337913fa6546b606b8b1801e5 185 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 15 182 2.4E-35 T 14-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 Tharo_1954 f039cd0337913fa6546b606b8b1801e5 185 Gene3D G3DSA:3.90.1140.10 12 183 5.6E-46 T 14-10-2018 Tharo_1954 f039cd0337913fa6546b606b8b1801e5 185 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 14 182 20.679 T 14-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 Tharo_1954 f039cd0337913fa6546b606b8b1801e5 185 SUPERFAMILY SSF55144 15 184 1.27E-39 T 14-10-2018 IPR009097 Cyclic phosphodiesterase Tharo_1954 f039cd0337913fa6546b606b8b1801e5 185 Pfam PF02834 LigT like Phosphoesterase 100 144 1.5E-6 T 14-10-2018 IPR014051 Phosphoesterase, HXTX Tharo_1954 f039cd0337913fa6546b606b8b1801e5 185 Pfam PF02834 LigT like Phosphoesterase 22 98 8.2E-14 T 14-10-2018 IPR014051 Phosphoesterase, HXTX Tharo_1902 ac958051e280bddf085cd59cf062d6ad 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 308 7.2E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Tharo_1902 ac958051e280bddf085cd59cf062d6ad 310 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 26 305 4.3E-82 T 14-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 Tharo_1902 ac958051e280bddf085cd59cf062d6ad 310 Gene3D G3DSA:1.10.3720.10 71 308 4.1E-28 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_1902 ac958051e280bddf085cd59cf062d6ad 310 SUPERFAMILY SSF161098 36 295 2.09E-32 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_1455 80fa066fbd25a8e881ec846390a1d6c4 306 PRINTS PR00111 Alpha/beta hydrolase fold signature 250 264 1.3E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_1455 80fa066fbd25a8e881ec846390a1d6c4 306 PRINTS PR00111 Alpha/beta hydrolase fold signature 77 92 1.3E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_1455 80fa066fbd25a8e881ec846390a1d6c4 306 PRINTS PR00111 Alpha/beta hydrolase fold signature 123 136 1.3E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_1455 80fa066fbd25a8e881ec846390a1d6c4 306 Pfam PF12697 Alpha/beta hydrolase family 54 294 2.6E-17 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_1455 80fa066fbd25a8e881ec846390a1d6c4 306 SUPERFAMILY SSF53474 38 292 2.91E-47 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_1455 80fa066fbd25a8e881ec846390a1d6c4 306 Gene3D G3DSA:3.40.50.1820 34 304 1.4E-77 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_0629 1b706e37acd8b8a80ad7492242250611 298 SMART SM00382 30 210 2.1E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0629 1b706e37acd8b8a80ad7492242250611 298 Gene3D G3DSA:3.40.50.300 2 236 1.3E-65 T 14-10-2018 Tharo_0629 1b706e37acd8b8a80ad7492242250611 298 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_0629 1b706e37acd8b8a80ad7492242250611 298 SUPERFAMILY SSF52540 4 231 1.91E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0629 1b706e37acd8b8a80ad7492242250611 298 Pfam PF00005 ABC transporter 23 163 5.2E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_1666 830e3113b03e6a7a18bed09896c917ae 66 Pfam PF04102 SlyX 1 66 1.3E-21 T 14-10-2018 IPR007236 SlyX Tharo_1666 830e3113b03e6a7a18bed09896c917ae 66 Gene3D G3DSA:1.20.5.170 1 55 1.2E-5 T 14-10-2018 Tharo_1093 aa4ac2161b7e3544269154845017d7c5 79 PIRSF PIRSF037031 1 78 1.9E-29 T 14-10-2018 IPR005243 Redox-active disulphide protein 2 Tharo_1093 aa4ac2161b7e3544269154845017d7c5 79 TIGRFAM TIGR00412 redox_disulf_2: redox-active disulfide protein 2 1 76 2.4E-23 T 14-10-2018 IPR005243 Redox-active disulphide protein 2 Tharo_1093 aa4ac2161b7e3544269154845017d7c5 79 Gene3D G3DSA:3.40.30.10 1 76 2.2E-26 T 14-10-2018 Tharo_1093 aa4ac2161b7e3544269154845017d7c5 79 Pfam PF13192 Thioredoxin domain 3 76 1.5E-24 T 14-10-2018 IPR012336 Thioredoxin-like fold Tharo_1093 aa4ac2161b7e3544269154845017d7c5 79 SUPERFAMILY SSF52833 2 76 3.83E-17 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_0114 b0e57e0e74c86a9400be3a21b456bb15 177 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 175 8.4E-51 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0114 b0e57e0e74c86a9400be3a21b456bb15 177 SUPERFAMILY SSF47928 3 106 1.57E-24 T 14-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0114 b0e57e0e74c86a9400be3a21b456bb15 177 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 175 4.0E-42 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0114 b0e57e0e74c86a9400be3a21b456bb15 177 Gene3D G3DSA:1.10.520.20 2 106 3.5E-30 T 14-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0114 b0e57e0e74c86a9400be3a21b456bb15 177 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 177 18.853 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0114 b0e57e0e74c86a9400be3a21b456bb15 177 PRINTS PR00125 ATP synthase delta subunit signature 74 85 1.6E-24 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0114 b0e57e0e74c86a9400be3a21b456bb15 177 PRINTS PR00125 ATP synthase delta subunit signature 150 168 1.6E-24 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0114 b0e57e0e74c86a9400be3a21b456bb15 177 PRINTS PR00125 ATP synthase delta subunit signature 85 99 1.6E-24 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0114 b0e57e0e74c86a9400be3a21b456bb15 177 PRINTS PR00125 ATP synthase delta subunit signature 135 150 1.6E-24 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0114 b0e57e0e74c86a9400be3a21b456bb15 177 PRINTS PR00125 ATP synthase delta subunit signature 7 26 1.6E-24 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Tharo_0592 34e5b115a7361153f8e78a4bf46b86f1 272 Gene3D G3DSA:3.40.50.410 63 242 8.3E-29 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Tharo_0592 34e5b115a7361153f8e78a4bf46b86f1 272 SUPERFAMILY SSF53300 60 237 8.21E-26 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Tharo_0592 34e5b115a7361153f8e78a4bf46b86f1 272 SMART SM00327 61 243 5.1E-17 T 14-10-2018 IPR002035 von Willebrand factor, type A Tharo_0592 34e5b115a7361153f8e78a4bf46b86f1 272 Pfam PF00092 von Willebrand factor type A domain 64 235 8.1E-15 T 14-10-2018 IPR002035 von Willebrand factor, type A Tharo_3235 8ab1511b0e7dfeb6e235c77f953fbb42 694 Pfam PF03050 Transposase IS66 family 201 431 2.0E-57 T 14-10-2018 IPR004291 Transposase, IS66 Tharo_3235 8ab1511b0e7dfeb6e235c77f953fbb42 694 Pfam PF13007 Transposase C of IS166 homeodomain 59 112 2.1E-8 T 14-10-2018 IPR024463 Transposase TnpC, homeodomain Tharo_0946 1299b27168b7580e3cddcf15a79fa263 942 PRINTS PR00313 NodO calcium binding signature 791 799 1.1E-5 T 14-10-2018 Tharo_0946 1299b27168b7580e3cddcf15a79fa263 942 PRINTS PR00313 NodO calcium binding signature 208 219 1.1E-5 T 14-10-2018 Tharo_0946 1299b27168b7580e3cddcf15a79fa263 942 PRINTS PR00313 NodO calcium binding signature 800 809 1.1E-5 T 14-10-2018 Tharo_0946 1299b27168b7580e3cddcf15a79fa263 942 PRINTS PR00313 NodO calcium binding signature 514 522 1.1E-5 T 14-10-2018 Tharo_0946 1299b27168b7580e3cddcf15a79fa263 942 Gene3D G3DSA:2.150.10.10 725 873 8.4E-10 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal Tharo_0946 1299b27168b7580e3cddcf15a79fa263 942 Pfam PF13946 Domain of unknown function (DUF4214) 48 88 1.8E-5 T 14-10-2018 IPR025282 Domain of unknown function DUF4214 Tharo_0946 1299b27168b7580e3cddcf15a79fa263 942 SUPERFAMILY SSF51120 711 865 3.66E-9 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal Tharo_0946 1299b27168b7580e3cddcf15a79fa263 942 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 787 805 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site Tharo_0957 1c45e6ed99a592e818324ec742ec9d59 92 Gene3D G3DSA:3.30.2310.20 8 91 3.9E-38 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_0957 1c45e6ed99a592e818324ec742ec9d59 92 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 12 91 6.0E-39 T 14-10-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 Tharo_0957 1c45e6ed99a592e818324ec742ec9d59 92 SUPERFAMILY SSF143011 9 90 4.58E-26 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_0957 1c45e6ed99a592e818324ec742ec9d59 92 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 12 91 3.0E-32 T 14-10-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 Tharo_2537 4efcd8fa9658b66ab60bfb4ac01c1d23 615 Gene3D G3DSA:3.60.9.10 1 209 3.4E-86 T 14-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily Tharo_2537 4efcd8fa9658b66ab60bfb4ac01c1d23 615 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 222 615 4.9E-128 T 14-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 Tharo_2537 4efcd8fa9658b66ab60bfb4ac01c1d23 615 SUPERFAMILY SSF56228 1 208 2.49E-74 T 14-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily Tharo_2537 4efcd8fa9658b66ab60bfb4ac01c1d23 615 SUPERFAMILY SSF48310 216 615 3.4E-127 T 14-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 Tharo_2537 4efcd8fa9658b66ab60bfb4ac01c1d23 615 Gene3D G3DSA:1.10.599.10 240 615 1.6E-126 T 14-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 Tharo_2537 4efcd8fa9658b66ab60bfb4ac01c1d23 615 Gene3D G3DSA:1.10.569.10 242 443 1.6E-126 T 14-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 Tharo_2537 4efcd8fa9658b66ab60bfb4ac01c1d23 615 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 205 4.9E-79 T 14-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 Tharo_2537 4efcd8fa9658b66ab60bfb4ac01c1d23 615 SMART SM00790 3 206 1.4E-120 T 14-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 Tharo_1816 1c5415563eb32fb960d7f0bf40815322 249 Gene3D G3DSA:3.40.50.300 5 249 8.8E-58 T 14-10-2018 Tharo_1816 1c5415563eb32fb960d7f0bf40815322 249 Pfam PF00005 ABC transporter 20 175 2.1E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_1816 1c5415563eb32fb960d7f0bf40815322 249 SMART SM00382 28 222 6.1E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1816 1c5415563eb32fb960d7f0bf40815322 249 SUPERFAMILY SSF52540 6 244 5.62E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1816 1c5415563eb32fb960d7f0bf40815322 249 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 222 244 1.5E-6 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal Tharo_1234 00ae6dfa35eed39d749c6b5c6e35f013 311 Gene3D G3DSA:1.10.10.10 227 304 1.2E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1234 00ae6dfa35eed39d749c6b5c6e35f013 311 SUPERFAMILY SSF88659 208 305 5.61E-21 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Tharo_1234 00ae6dfa35eed39d749c6b5c6e35f013 311 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 73 299 4.0E-36 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Tharo_1234 00ae6dfa35eed39d749c6b5c6e35f013 311 Gene3D G3DSA:1.10.10.10 150 225 1.3E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1234 00ae6dfa35eed39d749c6b5c6e35f013 311 SUPERFAMILY SSF88946 39 147 4.58E-45 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Tharo_1234 00ae6dfa35eed39d749c6b5c6e35f013 311 SUPERFAMILY SSF88659 150 224 4.14E-9 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Tharo_1234 00ae6dfa35eed39d749c6b5c6e35f013 311 Gene3D G3DSA:1.10.601.10 28 146 2.1E-46 T 14-10-2018 Tharo_1234 00ae6dfa35eed39d749c6b5c6e35f013 311 TIGRFAM TIGR02394 rpoS_proteo: RNA polymerase sigma factor RpoS 31 311 2.4E-128 T 14-10-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Tharo_1234 00ae6dfa35eed39d749c6b5c6e35f013 311 Pfam PF00140 Sigma-70 factor, region 1.2 39 71 6.3E-13 T 14-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Tharo_1234 00ae6dfa35eed39d749c6b5c6e35f013 311 Pfam PF04539 Sigma-70 region 3 157 230 1.8E-10 T 14-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 Tharo_1234 00ae6dfa35eed39d749c6b5c6e35f013 311 Pfam PF04542 Sigma-70 region 2 77 146 3.3E-20 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Tharo_1234 00ae6dfa35eed39d749c6b5c6e35f013 311 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 101 114 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_1234 00ae6dfa35eed39d749c6b5c6e35f013 311 PRINTS PR00046 Major sigma-70 factor signature 270 285 1.6E-22 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_1234 00ae6dfa35eed39d749c6b5c6e35f013 311 PRINTS PR00046 Major sigma-70 factor signature 285 296 1.6E-22 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_1234 00ae6dfa35eed39d749c6b5c6e35f013 311 PRINTS PR00046 Major sigma-70 factor signature 249 261 1.6E-22 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_1234 00ae6dfa35eed39d749c6b5c6e35f013 311 PRINTS PR00046 Major sigma-70 factor signature 101 114 1.6E-22 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_1234 00ae6dfa35eed39d749c6b5c6e35f013 311 PRINTS PR00046 Major sigma-70 factor signature 125 133 1.6E-22 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_1234 00ae6dfa35eed39d749c6b5c6e35f013 311 Pfam PF04545 Sigma-70, region 4 246 298 4.2E-12 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 Tharo_1234 00ae6dfa35eed39d749c6b5c6e35f013 311 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 270 296 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Tharo_1234 00ae6dfa35eed39d749c6b5c6e35f013 311 Hamap MF_00959 RNA polymerase sigma factor RpoS [rpoS]. 2 311 37.356 T 14-10-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Tharo_2130 4f593dc81cb8137cf2ecd3db7f96bec0 91 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 5 81 3.0E-18 T 14-10-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system Tharo_2130 4f593dc81cb8137cf2ecd3db7f96bec0 91 Gene3D G3DSA:3.10.450.530 1 85 3.3E-5 T 14-10-2018 IPR038573 Ribonuclease toxin BrnT superfamily Tharo_0180 7688a2448c74b301808e5d38b6978e5a 320 SMART SM00421 251 308 3.5E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_0180 7688a2448c74b301808e5d38b6978e5a 320 Gene3D G3DSA:1.10.10.10 172 318 1.4E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0180 7688a2448c74b301808e5d38b6978e5a 320 ProSitePatterns PS00622 LuxR-type HTH domain signature. 268 295 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_0180 7688a2448c74b301808e5d38b6978e5a 320 Pfam PF00196 Bacterial regulatory proteins, luxR family 253 308 2.4E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_0180 7688a2448c74b301808e5d38b6978e5a 320 SUPERFAMILY SSF46894 237 311 6.46E-17 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_0180 7688a2448c74b301808e5d38b6978e5a 320 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 254 268 5.9E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_0180 7688a2448c74b301808e5d38b6978e5a 320 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 284 296 5.9E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_0180 7688a2448c74b301808e5d38b6978e5a 320 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 268 284 5.9E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_3417 bbd4fe47339b1a7c113ae5955b001f0c 256 TIGRFAM TIGR02780 TrbJ_Ti: P-type conjugative transfer protein TrbJ 6 254 3.9E-58 T 14-10-2018 IPR014147 Type IV conjugative transfer protein TrbJ Tharo_3417 bbd4fe47339b1a7c113ae5955b001f0c 256 SUPERFAMILY SSF101082 29 232 1.83E-35 T 14-10-2018 Tharo_1215 602b09789f6a0ff7010ae0a6555f49c1 296 TIGRFAM TIGR01138 cysM: cysteine synthase B 5 294 1.7E-139 T 14-10-2018 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 Tharo_1215 602b09789f6a0ff7010ae0a6555f49c1 296 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 294 3.9E-120 T 14-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 Tharo_1215 602b09789f6a0ff7010ae0a6555f49c1 296 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 283 2.3E-66 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Tharo_1215 602b09789f6a0ff7010ae0a6555f49c1 296 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 14-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 Tharo_1215 602b09789f6a0ff7010ae0a6555f49c1 296 Gene3D G3DSA:3.40.50.1100 10 290 6.0E-110 T 14-10-2018 Tharo_1215 602b09789f6a0ff7010ae0a6555f49c1 296 Gene3D G3DSA:3.40.50.1100 37 142 6.0E-110 T 14-10-2018 Tharo_1215 602b09789f6a0ff7010ae0a6555f49c1 296 SUPERFAMILY SSF53686 3 291 9.17E-93 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Tharo_0442 a7f51a9f2688021354e6fd018f60a03c 284 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 10 281 44.998 T 14-10-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 Tharo_0442 a7f51a9f2688021354e6fd018f60a03c 284 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 49 279 2.9E-73 T 14-10-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 Tharo_0442 a7f51a9f2688021354e6fd018f60a03c 284 Pfam PF02666 Phosphatidylserine decarboxylase 63 278 1.2E-60 T 14-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 Tharo_1732 7293a224e158de6832df7f4e27716a62 241 SUPERFAMILY SSF52172 5 137 1.39E-35 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1732 7293a224e158de6832df7f4e27716a62 241 Pfam PF00072 Response regulator receiver domain 8 120 5.5E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1732 7293a224e158de6832df7f4e27716a62 241 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 206 218 3.2E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_1732 7293a224e158de6832df7f4e27716a62 241 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 190 3.2E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_1732 7293a224e158de6832df7f4e27716a62 241 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 206 3.2E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_1732 7293a224e158de6832df7f4e27716a62 241 SMART SM00421 173 230 2.3E-26 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_1732 7293a224e158de6832df7f4e27716a62 241 Pfam PF00196 Bacterial regulatory proteins, luxR family 175 230 4.3E-24 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_1732 7293a224e158de6832df7f4e27716a62 241 ProSitePatterns PS00622 LuxR-type HTH domain signature. 190 217 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_1732 7293a224e158de6832df7f4e27716a62 241 SMART SM00448 6 119 4.5E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1732 7293a224e158de6832df7f4e27716a62 241 Gene3D G3DSA:3.40.50.12740 6 236 4.2E-70 T 14-10-2018 Tharo_1732 7293a224e158de6832df7f4e27716a62 241 SUPERFAMILY SSF46894 167 237 1.29E-23 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_0187 cf405b3bc99ab8583cf041a0189e9e47 303 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 1.4E-83 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_0187 cf405b3bc99ab8583cf041a0189e9e47 303 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 1.4E-83 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_0187 cf405b3bc99ab8583cf041a0189e9e47 303 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 1.4E-83 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_0187 cf405b3bc99ab8583cf041a0189e9e47 303 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 1.4E-83 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_0187 cf405b3bc99ab8583cf041a0189e9e47 303 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 1.4E-83 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_0187 cf405b3bc99ab8583cf041a0189e9e47 303 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 1.4E-83 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_0187 cf405b3bc99ab8583cf041a0189e9e47 303 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 1.4E-83 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_0187 cf405b3bc99ab8583cf041a0189e9e47 303 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 5.6E-38 T 14-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_0187 cf405b3bc99ab8583cf041a0189e9e47 303 Gene3D G3DSA:3.40.50.720 6 258 2.3E-108 T 14-10-2018 Tharo_0187 cf405b3bc99ab8583cf041a0189e9e47 303 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 14-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_0187 cf405b3bc99ab8583cf041a0189e9e47 303 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 280 4.2E-68 T 14-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_0187 cf405b3bc99ab8583cf041a0189e9e47 303 SUPERFAMILY SSF53223 1 121 1.82E-38 T 14-10-2018 Tharo_0187 cf405b3bc99ab8583cf041a0189e9e47 303 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 37.756 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Tharo_0187 cf405b3bc99ab8583cf041a0189e9e47 303 SUPERFAMILY SSF51735 122 280 5.82E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_0187 cf405b3bc99ab8583cf041a0189e9e47 303 Gene3D G3DSA:3.40.50.10860 8 275 2.3E-108 T 14-10-2018 Tharo_3468 b448e41c6f91aad649a6f83e7618d7ef 84 ProDom PD028710 PLASMID KORC REPRESSOR TRANSCRIPTIONAL TRANSCRIPTION DNA-BINDING REGULATION KLCC 19 83 2.0E-16 T 14-10-2018 IPR020136 Transcriptional repressor KorC Tharo_1935 1c910afeb36a7b9d83c797841639c3f6 220 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 43 204 1.6E-42 T 14-10-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like Tharo_1935 1c910afeb36a7b9d83c797841639c3f6 220 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 18 214 29.388 T 14-10-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 Tharo_1935 1c910afeb36a7b9d83c797841639c3f6 220 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 21 209 7.7E-18 T 14-10-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 Tharo_1935 1c910afeb36a7b9d83c797841639c3f6 220 SUPERFAMILY SSF89392 33 213 9.81E-44 T 14-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX Tharo_1935 1c910afeb36a7b9d83c797841639c3f6 220 Gene3D G3DSA:2.50.20.10 28 213 9.7E-53 T 14-10-2018 Tharo_2693 6623bbe933eed6adcd5b55b005f91ef6 320 SUPERFAMILY SSF56281 7 261 1.7E-51 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_2693 6623bbe933eed6adcd5b55b005f91ef6 320 Gene3D G3DSA:3.60.15.10 7 269 1.5E-60 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_2693 6623bbe933eed6adcd5b55b005f91ef6 320 SMART SM00849 23 228 4.0E-29 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_2693 6623bbe933eed6adcd5b55b005f91ef6 320 Pfam PF00753 Metallo-beta-lactamase superfamily 25 219 2.7E-22 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_1044 983a79bc235ad520a0a02e97d9aa53d0 829 Gene3D G3DSA:3.40.50.300 247 455 1.8E-55 T 14-10-2018 Tharo_1044 983a79bc235ad520a0a02e97d9aa53d0 829 Gene3D G3DSA:3.40.50.300 11 180 7.4E-22 T 14-10-2018 Tharo_1044 983a79bc235ad520a0a02e97d9aa53d0 829 SUPERFAMILY SSF54211 571 763 1.71E-36 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Tharo_1044 983a79bc235ad520a0a02e97d9aa53d0 829 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 653 672 2.8E-10 T 14-10-2018 Tharo_1044 983a79bc235ad520a0a02e97d9aa53d0 829 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 572 588 2.8E-10 T 14-10-2018 Tharo_1044 983a79bc235ad520a0a02e97d9aa53d0 829 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 713 731 2.8E-10 T 14-10-2018 Tharo_1044 983a79bc235ad520a0a02e97d9aa53d0 829 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 683 702 2.8E-10 T 14-10-2018 Tharo_1044 983a79bc235ad520a0a02e97d9aa53d0 829 Pfam PF13654 AAA domain 30 546 5.7E-178 T 14-10-2018 Tharo_1044 983a79bc235ad520a0a02e97d9aa53d0 829 SUPERFAMILY SSF52540 42 545 7.22E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1044 983a79bc235ad520a0a02e97d9aa53d0 829 Gene3D G3DSA:3.30.230.10 549 783 1.5E-93 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Tharo_1044 983a79bc235ad520a0a02e97d9aa53d0 829 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 656 760 3.0E-8 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 Tharo_1044 983a79bc235ad520a0a02e97d9aa53d0 829 Gene3D G3DSA:1.10.8.60 456 543 4.1E-8 T 14-10-2018 Tharo_1268 151d411fb8eddce487a366b127a33872 226 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 7 206 2.2E-79 T 14-10-2018 IPR010968 Ion-translocating oxidoreductase complex subunit E GO:0016020|GO:0022900 Tharo_1268 151d411fb8eddce487a366b127a33872 226 Hamap MF_00478 Ion-translocating oxidoreductase complex subunit E [rsxE]. 1 210 26.651 T 14-10-2018 IPR010968 Ion-translocating oxidoreductase complex subunit E GO:0016020|GO:0022900 Tharo_1268 151d411fb8eddce487a366b127a33872 226 Pfam PF02508 Rnf-Nqr subunit, membrane protein 7 199 2.0E-63 T 14-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 Tharo_1268 151d411fb8eddce487a366b127a33872 226 PIRSF PIRSF006102 1 219 2.3E-73 T 14-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 Tharo_3113 2ad5affa6a37a832ebc68516872449a3 647 Pfam PF01292 Prokaryotic cytochrome b561 330 453 1.6E-7 T 14-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 Tharo_3113 2ad5affa6a37a832ebc68516872449a3 647 SUPERFAMILY SSF48695 16 505 7.95E-44 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily Tharo_3113 2ad5affa6a37a832ebc68516872449a3 647 Gene3D G3DSA:1.20.950.20 377 608 5.7E-39 T 14-10-2018 Tharo_3113 2ad5affa6a37a832ebc68516872449a3 647 Gene3D G3DSA:3.90.10.10 38 183 5.0E-5 T 14-10-2018 Tharo_0947 718f594d3f5cb03dad394765fbc96e3f 366 SMART SM01321 12 189 5.2E-4 T 14-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 Tharo_0947 718f594d3f5cb03dad394765fbc96e3f 366 SUPERFAMILY SSF143422 16 195 2.75E-17 T 14-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 Tharo_1180 25dde97dc0c1392626c077c96171b6f5 469 Gene3D G3DSA:3.30.499.20 5 288 5.4E-97 T 14-10-2018 Tharo_1180 25dde97dc0c1392626c077c96171b6f5 469 SUPERFAMILY SSF53732 3 468 1.44E-161 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 Tharo_1180 25dde97dc0c1392626c077c96171b6f5 469 ProSitePatterns PS01244 Aconitase family signature 2. 402 415 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Tharo_1180 25dde97dc0c1392626c077c96171b6f5 469 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 3 467 5.8E-234 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 Tharo_1180 25dde97dc0c1392626c077c96171b6f5 469 Pfam PF00330 Aconitase family (aconitate hydratase) 8 460 1.6E-155 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Tharo_1180 25dde97dc0c1392626c077c96171b6f5 469 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 469 59.347 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 Tharo_1180 25dde97dc0c1392626c077c96171b6f5 469 PRINTS PR00415 Aconitase family signature 211 224 8.3E-43 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Tharo_1180 25dde97dc0c1392626c077c96171b6f5 469 PRINTS PR00415 Aconitase family signature 402 415 8.3E-43 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Tharo_1180 25dde97dc0c1392626c077c96171b6f5 469 PRINTS PR00415 Aconitase family signature 135 150 8.3E-43 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Tharo_1180 25dde97dc0c1392626c077c96171b6f5 469 PRINTS PR00415 Aconitase family signature 121 134 8.3E-43 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Tharo_1180 25dde97dc0c1392626c077c96171b6f5 469 PRINTS PR00415 Aconitase family signature 345 356 8.3E-43 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Tharo_1180 25dde97dc0c1392626c077c96171b6f5 469 PRINTS PR00415 Aconitase family signature 110 118 8.3E-43 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Tharo_1180 25dde97dc0c1392626c077c96171b6f5 469 PRINTS PR00415 Aconitase family signature 197 210 8.3E-43 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Tharo_1180 25dde97dc0c1392626c077c96171b6f5 469 PRINTS PR00415 Aconitase family signature 288 302 8.3E-43 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Tharo_1180 25dde97dc0c1392626c077c96171b6f5 469 Gene3D G3DSA:3.30.499.10 328 469 1.2E-48 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 Tharo_1180 25dde97dc0c1392626c077c96171b6f5 469 ProSitePatterns PS00450 Aconitase family signature 1. 341 357 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Tharo_0882 787c363c9042696d39cb1603293f24c8 299 Gene3D G3DSA:3.40.91.100 131 291 2.0E-10 T 14-10-2018 Tharo_0882 787c363c9042696d39cb1603293f24c8 299 Pfam PF04471 Restriction endonuclease 157 272 3.9E-34 T 14-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 Tharo_0882 787c363c9042696d39cb1603293f24c8 299 Pfam PF14338 Mrr N-terminal domain 6 89 5.2E-25 T 14-10-2018 IPR025745 Restriction system protein Mrr-like N-terminal domain Tharo_0882 787c363c9042696d39cb1603293f24c8 299 SUPERFAMILY SSF52980 162 277 4.24E-17 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Tharo_2298 32777b3ae8a775d2a5fae06ed63c7d4e 476 SUPERFAMILY SSF81442 6 465 1.44E-126 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_2298 32777b3ae8a775d2a5fae06ed63c7d4e 476 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 6 467 2.7E-238 T 14-10-2018 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 Tharo_2298 32777b3ae8a775d2a5fae06ed63c7d4e 476 Gene3D G3DSA:1.20.210.10 1 470 1.3E-205 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_2298 32777b3ae8a775d2a5fae06ed63c7d4e 476 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 202 257 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_2298 32777b3ae8a775d2a5fae06ed63c7d4e 476 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 10 442 9.8E-117 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_2367 b38a8b7afa185b15dfadf789754936f0 83 Pfam PF01402 Ribbon-helix-helix protein, copG family 3 40 4.6E-9 T 14-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 Tharo_2367 b38a8b7afa185b15dfadf789754936f0 83 SUPERFAMILY SSF47598 2 40 4.73E-8 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Tharo_0339 a432f4aa833eeac85fffcc010feba83d 546 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 499 542 4.7E-9 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain Tharo_0339 a432f4aa833eeac85fffcc010feba83d 546 SUPERFAMILY SSF64518 123 543 1.7E-41 T 14-10-2018 Tharo_0339 a432f4aa833eeac85fffcc010feba83d 546 PRINTS PR01005 Flagellar hook-associated protein signature 10 33 1.1E-38 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 Tharo_0339 a432f4aa833eeac85fffcc010feba83d 546 PRINTS PR01005 Flagellar hook-associated protein signature 205 223 1.1E-38 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 Tharo_0339 a432f4aa833eeac85fffcc010feba83d 546 PRINTS PR01005 Flagellar hook-associated protein signature 249 271 1.1E-38 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 Tharo_0339 a432f4aa833eeac85fffcc010feba83d 546 PRINTS PR01005 Flagellar hook-associated protein signature 146 170 1.1E-38 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 Tharo_0339 a432f4aa833eeac85fffcc010feba83d 546 PRINTS PR01005 Flagellar hook-associated protein signature 464 485 1.1E-38 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 Tharo_0339 a432f4aa833eeac85fffcc010feba83d 546 PRINTS PR01005 Flagellar hook-associated protein signature 439 458 1.1E-38 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 Tharo_0339 a432f4aa833eeac85fffcc010feba83d 546 PRINTS PR01005 Flagellar hook-associated protein signature 511 535 1.1E-38 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 Tharo_0339 a432f4aa833eeac85fffcc010feba83d 546 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 6 325 1.6E-64 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 Tharo_0530 21eae56b1851450958967ba945d43759 249 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 8 238 3.5E-15 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase Tharo_0530 21eae56b1851450958967ba945d43759 249 SUPERFAMILY SSF56219 1 245 6.94E-47 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Tharo_0530 21eae56b1851450958967ba945d43759 249 Gene3D G3DSA:3.60.10.10 1 247 3.9E-41 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Tharo_0297 fff5abe1c40e2b6eaff6e69beb3e7763 205 SUPERFAMILY SSF53335 25 191 1.17E-39 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_0297 fff5abe1c40e2b6eaff6e69beb3e7763 205 Gene3D G3DSA:3.40.50.150 3 197 3.4E-39 T 14-10-2018 Tharo_0297 fff5abe1c40e2b6eaff6e69beb3e7763 205 Pfam PF08241 Methyltransferase domain 50 147 2.6E-22 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 Tharo_0075 ab60d2fe8bd01e54357deaa089564e4f 320 Pfam PF03741 Integral membrane protein TerC family 80 282 4.1E-56 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 Tharo_0075 ab60d2fe8bd01e54357deaa089564e4f 320 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 6 312 1.1E-122 T 14-10-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 Tharo_1512 38c9f63a80018d228c302808cba81cb2 408 Pfam PF07690 Major Facilitator Superfamily 32 352 3.3E-17 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_1512 38c9f63a80018d228c302808cba81cb2 408 Gene3D G3DSA:1.20.1250.20 209 396 3.6E-19 T 14-10-2018 Tharo_1512 38c9f63a80018d228c302808cba81cb2 408 SUPERFAMILY SSF103473 11 397 1.29E-41 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_1512 38c9f63a80018d228c302808cba81cb2 408 Gene3D G3DSA:1.20.1250.20 10 197 4.9E-13 T 14-10-2018 Tharo_0852 c94e9df2a05afe914a024fd547c59502 345 Pfam PF04794 YdjC-like protein 44 307 5.9E-47 T 14-10-2018 IPR006879 Carbohydrate deacetylase YdjC-like Tharo_0852 c94e9df2a05afe914a024fd547c59502 345 Gene3D G3DSA:3.20.20.370 42 321 8.3E-34 T 14-10-2018 Tharo_0852 c94e9df2a05afe914a024fd547c59502 345 SUPERFAMILY SSF88713 42 319 1.0E-58 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Tharo_2866 c8c45bd9f67f2ef039ac3a94ebabb076 148 SUPERFAMILY SSF143880 6 84 7.45E-16 T 14-10-2018 IPR036782 NE0471-like, N-terminal Tharo_2866 c8c45bd9f67f2ef039ac3a94ebabb076 148 Gene3D G3DSA:1.10.260.40 86 148 9.9E-23 T 14-10-2018 Tharo_2866 c8c45bd9f67f2ef039ac3a94ebabb076 148 Pfam PF10387 Protein of unknown function (DUF2442) 9 79 1.1E-7 T 14-10-2018 IPR018841 Protein of unknown function DUF2442 Tharo_2866 c8c45bd9f67f2ef039ac3a94ebabb076 148 SUPERFAMILY SSF47413 91 144 1.63E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_2866 c8c45bd9f67f2ef039ac3a94ebabb076 148 Gene3D G3DSA:3.30.2020.10 3 85 3.4E-18 T 14-10-2018 IPR036782 NE0471-like, N-terminal Tharo_0274 2e51fe30298c981cc3c372a0bb569e08 197 Gene3D G3DSA:3.40.190.10 8 176 3.9E-15 T 14-10-2018 Tharo_0274 2e51fe30298c981cc3c372a0bb569e08 197 SUPERFAMILY SSF53850 9 190 1.57E-16 T 14-10-2018 Tharo_0274 2e51fe30298c981cc3c372a0bb569e08 197 Gene3D G3DSA:3.40.190.10 69 172 3.9E-15 T 14-10-2018 Tharo_0274 2e51fe30298c981cc3c372a0bb569e08 197 Pfam PF03466 LysR substrate binding domain 11 190 2.7E-16 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_2067 d473ff364f8531fd8a5f1d9e9d462dcc 244 Gene3D G3DSA:1.10.287.610 95 142 5.2E-86 T 14-10-2018 Tharo_2067 d473ff364f8531fd8a5f1d9e9d462dcc 244 Gene3D G3DSA:3.40.50.10490 1 211 5.2E-86 T 14-10-2018 Tharo_2067 d473ff364f8531fd8a5f1d9e9d462dcc 244 PRINTS PR00395 Ribosomal protein S2 signature 188 202 2.1E-24 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2067 d473ff364f8531fd8a5f1d9e9d462dcc 244 PRINTS PR00395 Ribosomal protein S2 signature 29 38 2.1E-24 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2067 d473ff364f8531fd8a5f1d9e9d462dcc 244 PRINTS PR00395 Ribosomal protein S2 signature 79 96 2.1E-24 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2067 d473ff364f8531fd8a5f1d9e9d462dcc 244 PRINTS PR00395 Ribosomal protein S2 signature 167 178 2.1E-24 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2067 d473ff364f8531fd8a5f1d9e9d462dcc 244 PRINTS PR00395 Ribosomal protein S2 signature 150 167 2.1E-24 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2067 d473ff364f8531fd8a5f1d9e9d462dcc 244 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 1 218 3.5E-97 T 14-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2067 d473ff364f8531fd8a5f1d9e9d462dcc 244 SUPERFAMILY SSF52313 1 223 1.19E-90 T 14-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily Tharo_2067 d473ff364f8531fd8a5f1d9e9d462dcc 244 Pfam PF00318 Ribosomal protein S2 1 216 9.0E-92 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2067 d473ff364f8531fd8a5f1d9e9d462dcc 244 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 1 217 37.83 T 14-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1800 a7e9a8ca656bee806916d458540e973a 359 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 7 349 2.0E-142 T 14-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 Tharo_1800 a7e9a8ca656bee806916d458540e973a 359 SUPERFAMILY SSF51569 8 349 2.56E-129 T 14-10-2018 Tharo_1800 a7e9a8ca656bee806916d458540e973a 359 Gene3D G3DSA:3.20.20.70 3 352 2.9E-145 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_1800 a7e9a8ca656bee806916d458540e973a 359 PIRSF PIRSF001361 2 355 6.6E-155 T 14-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 Tharo_1800 a7e9a8ca656bee806916d458540e973a 359 Pfam PF00793 DAHP synthetase I family 45 340 8.2E-87 T 14-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 Tharo_0351 171d51f54607790a9b4df39d872d5ee6 472 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 21 467 4.1E-175 T 14-10-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Tharo_0351 171d51f54607790a9b4df39d872d5ee6 472 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 378 387 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Tharo_0351 171d51f54607790a9b4df39d872d5ee6 472 SUPERFAMILY SSF52540 124 392 5.12E-93 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0351 171d51f54607790a9b4df39d872d5ee6 472 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 176 387 8.9E-72 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Tharo_0351 171d51f54607790a9b4df39d872d5ee6 472 TIGRFAM TIGR03496 FliI_clade1: flagellar protein export ATPase FliI 42 465 6.2E-192 T 14-10-2018 IPR020005 Flagellar export ATPase FliI, clade 1 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Tharo_0351 171d51f54607790a9b4df39d872d5ee6 472 Gene3D G3DSA:3.40.50.12240 33 470 9.3E-158 T 14-10-2018 Tharo_0351 171d51f54607790a9b4df39d872d5ee6 472 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 44 109 6.2E-4 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Tharo_0351 171d51f54607790a9b4df39d872d5ee6 472 SMART SM00382 188 371 1.3E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2430 18b27784656e882c953f92f902594b9b 394 SUPERFAMILY SSF53748 4 390 2.36E-141 T 14-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2430 18b27784656e882c953f92f902594b9b 394 Pfam PF00162 Phosphoglycerate kinase 7 380 4.2E-139 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2430 18b27784656e882c953f92f902594b9b 394 Gene3D G3DSA:3.40.50.1260 167 380 2.7E-145 T 14-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2430 18b27784656e882c953f92f902594b9b 394 PRINTS PR00477 Phosphoglycerate kinase family signature 188 207 1.3E-83 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2430 18b27784656e882c953f92f902594b9b 394 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 1.3E-83 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2430 18b27784656e882c953f92f902594b9b 394 PRINTS PR00477 Phosphoglycerate kinase family signature 32 54 1.3E-83 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2430 18b27784656e882c953f92f902594b9b 394 PRINTS PR00477 Phosphoglycerate kinase family signature 343 354 1.3E-83 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2430 18b27784656e882c953f92f902594b9b 394 PRINTS PR00477 Phosphoglycerate kinase family signature 310 335 1.3E-83 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2430 18b27784656e882c953f92f902594b9b 394 PRINTS PR00477 Phosphoglycerate kinase family signature 366 383 1.3E-83 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2430 18b27784656e882c953f92f902594b9b 394 PRINTS PR00477 Phosphoglycerate kinase family signature 106 121 1.3E-83 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2430 18b27784656e882c953f92f902594b9b 394 PRINTS PR00477 Phosphoglycerate kinase family signature 134 156 1.3E-83 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2430 18b27784656e882c953f92f902594b9b 394 PRINTS PR00477 Phosphoglycerate kinase family signature 165 187 1.3E-83 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2430 18b27784656e882c953f92f902594b9b 394 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 390 38.666 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2430 18b27784656e882c953f92f902594b9b 394 Gene3D G3DSA:3.40.50.1260 8 388 2.7E-145 T 14-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2430 18b27784656e882c953f92f902594b9b 394 PIRSF PIRSF000724 1 394 7.4E-137 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_2430 18b27784656e882c953f92f902594b9b 394 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 14-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1702 4774367401a7523bf2deea398f6da240 309 Pfam PF03186 CobD/Cbib protein 28 286 8.1E-14 T 14-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 Tharo_1702 4774367401a7523bf2deea398f6da240 309 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 309 49.548 T 14-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 Tharo_0265 8021fb70d3f99a0485e435b194dc5183 147 Gene3D G3DSA:2.40.50.140 29 135 5.7E-40 T 14-10-2018 Tharo_0265 8021fb70d3f99a0485e435b194dc5183 147 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 1 139 33.07 T 14-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 Tharo_0265 8021fb70d3f99a0485e435b194dc5183 147 Pfam PF03100 CcmE 4 129 2.3E-48 T 14-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 Tharo_0265 8021fb70d3f99a0485e435b194dc5183 147 SUPERFAMILY SSF82093 29 134 5.36E-40 T 14-10-2018 IPR036127 CcmE-like superfamily GO:0005886|GO:0017003|GO:0017004 Tharo_1090 25239aced3f3ffd7809d1f79c6ded785 123 SUPERFAMILY SSF88723 1 119 2.05E-16 T 14-10-2018 IPR029060 PIN-like domain superfamily Tharo_1090 25239aced3f3ffd7809d1f79c6ded785 123 Pfam PF01850 PIN domain 2 109 1.9E-6 T 14-10-2018 IPR002716 PIN domain Tharo_1090 25239aced3f3ffd7809d1f79c6ded785 123 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 119 10.345 T 14-10-2018 IPR022907 VapC family GO:0004540 Tharo_1090 25239aced3f3ffd7809d1f79c6ded785 123 Gene3D G3DSA:3.40.50.1010 1 119 5.6E-11 T 14-10-2018 Tharo_0094 b89d757d3e6fbb63c1c37358d24182e0 276 SUPERFAMILY SSF53850 36 262 1.83E-34 T 14-10-2018 Tharo_0094 b89d757d3e6fbb63c1c37358d24182e0 276 Gene3D G3DSA:3.40.190.10 112 223 3.1E-91 T 14-10-2018 Tharo_0094 b89d757d3e6fbb63c1c37358d24182e0 276 Gene3D G3DSA:3.40.190.10 37 260 3.1E-91 T 14-10-2018 Tharo_0094 b89d757d3e6fbb63c1c37358d24182e0 276 Pfam PF12849 PBP superfamily domain 31 254 1.7E-29 T 14-10-2018 IPR024370 PBP domain Tharo_3072 00cb768d0d59838a562a4dbbf7b14a3e 286 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 191 253 8.2E-5 T 14-10-2018 IPR013615 CbbQ/NirQ/NorQ, C-terminal Tharo_3072 00cb768d0d59838a562a4dbbf7b14a3e 286 Pfam PF07728 AAA domain (dynein-related subfamily) 42 178 1.1E-19 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 Tharo_3072 00cb768d0d59838a562a4dbbf7b14a3e 286 Gene3D G3DSA:3.40.50.300 27 196 7.8E-21 T 14-10-2018 Tharo_3072 00cb768d0d59838a562a4dbbf7b14a3e 286 SUPERFAMILY SSF52540 14 211 7.34E-27 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3303 b392366825a886c8385aa311d4995008 142 Pfam PF13279 Thioesterase-like superfamily 24 137 1.2E-17 T 14-10-2018 Tharo_3303 b392366825a886c8385aa311d4995008 142 SUPERFAMILY SSF54637 2 137 1.44E-23 T 14-10-2018 IPR029069 HotDog domain superfamily Tharo_3303 b392366825a886c8385aa311d4995008 142 Gene3D G3DSA:3.10.129.10 2 141 5.5E-23 T 14-10-2018 Tharo_1629 7d5de6c0d10550d9a7fec7b3754ac3a7 296 SMART SM00729 10 240 9.0E-34 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Tharo_1629 7d5de6c0d10550d9a7fec7b3754ac3a7 296 SUPERFAMILY SSF102114 3 247 3.79E-44 T 14-10-2018 Tharo_1629 7d5de6c0d10550d9a7fec7b3754ac3a7 296 Pfam PF16199 Radical_SAM C-terminal domain 201 279 1.8E-16 T 14-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 Tharo_1629 7d5de6c0d10550d9a7fec7b3754ac3a7 296 Gene3D G3DSA:3.80.30.20 84 252 1.1E-13 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Tharo_1629 7d5de6c0d10550d9a7fec7b3754ac3a7 296 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 1 293 2.2E-89 T 14-10-2018 IPR005911 Protein YhcC-like GO:0051536 Tharo_1629 7d5de6c0d10550d9a7fec7b3754ac3a7 296 Pfam PF04055 Radical SAM superfamily 30 189 4.5E-15 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_3210 d945b885b55e3a79f7f599694b599291 226 SUPERFAMILY SSF63965 9 216 5.62E-64 T 14-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 Tharo_3210 d945b885b55e3a79f7f599694b599291 226 Gene3D G3DSA:3.40.50.10230 5 225 1.2E-76 T 14-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 Tharo_3210 d945b885b55e3a79f7f599694b599291 226 Pfam PF02570 Precorrin-8X methylmutase 17 213 7.1E-71 T 14-10-2018 IPR003722 Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC GO:0009236|GO:0016993 Tharo_0126 53e1f6039d91c411faaf078274ff785e 280 SUPERFAMILY SSF56235 2 249 1.03E-47 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Tharo_0126 53e1f6039d91c411faaf078274ff785e 280 Gene3D G3DSA:3.60.20.10 1 257 4.5E-98 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Tharo_0126 53e1f6039d91c411faaf078274ff785e 280 Pfam PF13230 Glutamine amidotransferases class-II 1 267 2.2E-126 T 14-10-2018 IPR026869 Putative glutamine amidotransferase type 2 Tharo_0142 fbd93a17547387a8812410e7761c856b 375 Gene3D G3DSA:2.60.410.10 267 356 1.6E-27 T 14-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Tharo_0142 fbd93a17547387a8812410e7761c856b 375 SUPERFAMILY SSF56601 3 267 1.17E-83 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Tharo_0142 fbd93a17547387a8812410e7761c856b 375 SMART SM00936 267 357 6.0E-29 T 14-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Tharo_0142 fbd93a17547387a8812410e7761c856b 375 Gene3D G3DSA:3.40.710.10 17 266 2.1E-89 T 14-10-2018 Tharo_0142 fbd93a17547387a8812410e7761c856b 375 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 107 124 7.0E-18 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 Tharo_0142 fbd93a17547387a8812410e7761c856b 375 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 54 65 7.0E-18 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 Tharo_0142 fbd93a17547387a8812410e7761c856b 375 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 134 147 7.0E-18 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 Tharo_0142 fbd93a17547387a8812410e7761c856b 375 SUPERFAMILY SSF69189 267 359 1.77E-23 T 14-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Tharo_0142 fbd93a17547387a8812410e7761c856b 375 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 267 356 5.9E-22 T 14-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Tharo_0142 fbd93a17547387a8812410e7761c856b 375 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 22 247 2.7E-81 T 14-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 Tharo_1002 85108cde6b74a1e17432fd34272929b5 436 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 432 9.2E-167 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Tharo_1002 85108cde6b74a1e17432fd34272929b5 436 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 436 204.043 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Tharo_1002 85108cde6b74a1e17432fd34272929b5 436 Pfam PF00709 Adenylosuccinate synthetase 5 428 2.9E-171 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Tharo_1002 85108cde6b74a1e17432fd34272929b5 436 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 134 145 - T 14-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Tharo_1002 85108cde6b74a1e17432fd34272929b5 436 Gene3D G3DSA:1.10.300.10 102 202 3.4E-92 T 14-10-2018 Tharo_1002 85108cde6b74a1e17432fd34272929b5 436 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 11 18 - T 14-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Tharo_1002 85108cde6b74a1e17432fd34272929b5 436 SMART SM00788 4 429 1.4E-282 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Tharo_1002 85108cde6b74a1e17432fd34272929b5 436 SUPERFAMILY SSF52540 3 434 5.31E-169 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1002 85108cde6b74a1e17432fd34272929b5 436 Gene3D G3DSA:3.40.440.10 6 250 3.4E-92 T 14-10-2018 Tharo_1002 85108cde6b74a1e17432fd34272929b5 436 Gene3D G3DSA:3.90.170.10 268 436 3.7E-67 T 14-10-2018 Tharo_1904 c20e4169f31867cec685dd71f32597a9 313 Pfam PF01545 Cation efflux family 29 217 1.8E-36 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Tharo_1904 c20e4169f31867cec685dd71f32597a9 313 Gene3D G3DSA:1.20.1510.10 23 218 5.7E-39 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Tharo_1904 c20e4169f31867cec685dd71f32597a9 313 SUPERFAMILY SSF161111 23 219 9.55E-49 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Tharo_1904 c20e4169f31867cec685dd71f32597a9 313 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 25 297 1.6E-77 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Tharo_1904 c20e4169f31867cec685dd71f32597a9 313 SUPERFAMILY SSF160240 225 298 3.92E-8 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 Tharo_2184 9ba46f3edc989b6ee5046b4ff608f439 363 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 5 358 1.1E-123 T 14-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 Tharo_2184 9ba46f3edc989b6ee5046b4ff608f439 363 Hamap MF_00259 Aminomethyltransferase [gcvT]. 4 358 44.625 T 14-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 Tharo_2184 9ba46f3edc989b6ee5046b4ff608f439 363 PIRSF PIRSF006487 1 361 4.6E-84 T 14-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 Tharo_2184 9ba46f3edc989b6ee5046b4ff608f439 363 Gene3D G3DSA:3.30.1360.120 9 235 2.8E-85 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 Tharo_2184 9ba46f3edc989b6ee5046b4ff608f439 363 Gene3D G3DSA:3.30.70.1400 54 141 2.8E-85 T 14-10-2018 Tharo_2184 9ba46f3edc989b6ee5046b4ff608f439 363 Gene3D G3DSA:4.10.1250.10 236 278 8.9E-21 T 14-10-2018 Tharo_2184 9ba46f3edc989b6ee5046b4ff608f439 363 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 267 353 4.5E-17 T 14-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 Tharo_2184 9ba46f3edc989b6ee5046b4ff608f439 363 Pfam PF01571 Aminomethyltransferase folate-binding domain 10 258 5.9E-88 T 14-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain Tharo_2184 9ba46f3edc989b6ee5046b4ff608f439 363 SUPERFAMILY SSF103025 4 275 7.96E-93 T 14-10-2018 Tharo_2184 9ba46f3edc989b6ee5046b4ff608f439 363 Gene3D G3DSA:2.40.30.110 279 363 1.8E-27 T 14-10-2018 Tharo_2184 9ba46f3edc989b6ee5046b4ff608f439 363 SUPERFAMILY SSF101790 275 359 9.48E-23 T 14-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal Tharo_0800 8ab7a66fd1fefdd2e84bb14efadbfe52 262 PIRSF PIRSF009437 1 262 5.0E-98 T 14-10-2018 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0010181|GO:0016021|GO:0016655 Tharo_0800 8ab7a66fd1fefdd2e84bb14efadbfe52 262 Hamap MF_00427 Na(+)-translocating NADH-quinone reductase subunit C [nqrC]. 6 262 34.511 T 14-10-2018 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0010181|GO:0016021|GO:0016655 Tharo_0800 8ab7a66fd1fefdd2e84bb14efadbfe52 262 Pfam PF04205 FMN-binding domain 147 245 1.7E-13 T 14-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 Tharo_0800 8ab7a66fd1fefdd2e84bb14efadbfe52 262 SMART SM00900 147 248 3.6E-31 T 14-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 Tharo_0800 8ab7a66fd1fefdd2e84bb14efadbfe52 262 TIGRFAM TIGR01938 nqrC: NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit 6 255 3.5E-85 T 14-10-2018 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0010181|GO:0016021|GO:0016655 Tharo_0495 c2fd88496adf798b254cd5f929c93ac9 196 Gene3D G3DSA:3.40.50.1820 1 195 5.7E-55 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_0495 c2fd88496adf798b254cd5f929c93ac9 196 SUPERFAMILY SSF53474 1 187 2.39E-18 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_0495 c2fd88496adf798b254cd5f929c93ac9 196 Pfam PF05728 Uncharacterised protein family (UPF0227) 1 188 8.9E-58 T 14-10-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA Tharo_3411 f8d66b12e6056c5ae6a0a6b685496aa3 103 PIRSF PIRSF017854 1 89 1.8E-32 T 14-10-2018 IPR016704 Conjugal transfer, TrbD Tharo_3411 f8d66b12e6056c5ae6a0a6b685496aa3 103 Pfam PF05101 Type IV secretory pathway, VirB3-like protein 6 85 8.9E-17 T 14-10-2018 IPR007792 Type IV secretion system, VirB3 / TrbD / AvhB Tharo_3411 f8d66b12e6056c5ae6a0a6b685496aa3 103 ProDom PD012561 TRBD PLASMID CONJUGAL TRANSFER PRECURSOR SIGNAL MATING FORMATION PROBABLE PAIR 13 93 4.0E-39 T 14-10-2018 Tharo_0886 47ff995d273b153ea4853b5bdac9419e 127 TIGRFAM TIGR00494 crcB: protein CrcB 8 121 1.6E-26 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Tharo_0886 47ff995d273b153ea4853b5bdac9419e 127 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 8 118 1.9E-22 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Tharo_0886 47ff995d273b153ea4853b5bdac9419e 127 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 6 123 18.161 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Tharo_2409 4ab00725670edcdebc6164df3d1e644f 240 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 17 239 9.9E-57 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 Tharo_2409 4ab00725670edcdebc6164df3d1e644f 240 SUPERFAMILY SSF88697 2 63 2.32E-13 T 14-10-2018 IPR015947 PUA-like superfamily Tharo_2409 4ab00725670edcdebc6164df3d1e644f 240 PIRSF PIRSF015601 1 239 7.3E-56 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 Tharo_2409 4ab00725670edcdebc6164df3d1e644f 240 Gene3D G3DSA:2.40.240.20 1 68 6.1E-17 T 14-10-2018 Tharo_2409 4ab00725670edcdebc6164df3d1e644f 240 SUPERFAMILY SSF75217 72 239 5.23E-53 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases Tharo_2409 4ab00725670edcdebc6164df3d1e644f 240 Pfam PF04452 RNA methyltransferase 19 235 3.4E-69 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 Tharo_2409 4ab00725670edcdebc6164df3d1e644f 240 Gene3D G3DSA:3.40.1280.10 72 240 4.8E-63 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Tharo_2570 41666295bf5ce676d6df7747f5714b07 80 SUPERFAMILY SSF47598 3 50 8.89E-6 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Tharo_0480 eafe9411764e143c2953819bce073f40 168 Gene3D G3DSA:3.40.50.2020 1 166 1.7E-39 T 14-10-2018 Tharo_0480 eafe9411764e143c2953819bce073f40 168 Pfam PF00156 Phosphoribosyl transferase domain 7 132 6.4E-16 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Tharo_0480 eafe9411764e143c2953819bce073f40 168 SUPERFAMILY SSF53271 7 140 1.84E-33 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Tharo_0766 8cfec46066bd74e8488d4d4158ca2675 346 PRINTS PR00184 Neisseria sp. porin signature 90 109 3.6E-12 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 Tharo_0766 8cfec46066bd74e8488d4d4158ca2675 346 PRINTS PR00184 Neisseria sp. porin signature 335 346 3.6E-12 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 Tharo_0766 8cfec46066bd74e8488d4d4158ca2675 346 PRINTS PR00184 Neisseria sp. porin signature 52 77 3.6E-12 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 Tharo_0766 8cfec46066bd74e8488d4d4158ca2675 346 Pfam PF13609 Gram-negative porin 7 311 1.4E-58 T 14-10-2018 Tharo_0766 8cfec46066bd74e8488d4d4158ca2675 346 Gene3D G3DSA:2.40.160.10 21 346 2.3E-72 T 14-10-2018 IPR023614 Porin domain superfamily Tharo_0766 8cfec46066bd74e8488d4d4158ca2675 346 SUPERFAMILY SSF56935 21 346 2.29E-66 T 14-10-2018 Tharo_0766 8cfec46066bd74e8488d4d4158ca2675 346 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 186 198 1.8E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 Tharo_0766 8cfec46066bd74e8488d4d4158ca2675 346 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 288 305 1.8E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 Tharo_0766 8cfec46066bd74e8488d4d4158ca2675 346 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 156 167 1.8E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 Tharo_0766 8cfec46066bd74e8488d4d4158ca2675 346 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 50 61 1.8E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 Tharo_1446 294054e73bba05524ae1f3f7bcc211e4 723 SUPERFAMILY SSF54862 502 674 2.22E-9 T 14-10-2018 Tharo_1446 294054e73bba05524ae1f3f7bcc211e4 723 SMART SM00900 95 189 1.1E-10 T 14-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 Tharo_1446 294054e73bba05524ae1f3f7bcc211e4 723 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 642 653 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_1446 294054e73bba05524ae1f3f7bcc211e4 723 Pfam PF12801 4Fe-4S binding domain 598 626 1.4E-4 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_1446 294054e73bba05524ae1f3f7bcc211e4 723 Pfam PF12801 4Fe-4S binding domain 490 535 2.3E-14 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_1446 294054e73bba05524ae1f3f7bcc211e4 723 PIRSF PIRSF036354 2 721 1.5E-167 T 14-10-2018 IPR011399 Nitrous oxide reductase expression regulator NosR GO:0003677|GO:0016020|GO:0045893 Tharo_2536 b9ac668528a9c7da87a33cadc96e0cd0 429 SUPERFAMILY SSF51905 143 312 8.52E-27 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_2536 b9ac668528a9c7da87a33cadc96e0cd0 429 SUPERFAMILY SSF51905 2 187 1.23E-38 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_2536 b9ac668528a9c7da87a33cadc96e0cd0 429 Gene3D G3DSA:3.50.50.60 111 240 6.1E-82 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_2536 b9ac668528a9c7da87a33cadc96e0cd0 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 4.0E-23 T 14-10-2018 Tharo_2536 b9ac668528a9c7da87a33cadc96e0cd0 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 4.0E-23 T 14-10-2018 Tharo_2536 b9ac668528a9c7da87a33cadc96e0cd0 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 4.0E-23 T 14-10-2018 Tharo_2536 b9ac668528a9c7da87a33cadc96e0cd0 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 4.0E-23 T 14-10-2018 Tharo_2536 b9ac668528a9c7da87a33cadc96e0cd0 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 4.0E-23 T 14-10-2018 Tharo_2536 b9ac668528a9c7da87a33cadc96e0cd0 429 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 290 5.9E-48 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Tharo_2536 b9ac668528a9c7da87a33cadc96e0cd0 429 Gene3D G3DSA:3.50.50.60 4 304 6.1E-82 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_2536 b9ac668528a9c7da87a33cadc96e0cd0 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 1.5E-10 T 14-10-2018 Tharo_2536 b9ac668528a9c7da87a33cadc96e0cd0 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 273 280 1.5E-10 T 14-10-2018 Tharo_2536 b9ac668528a9c7da87a33cadc96e0cd0 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 234 248 1.5E-10 T 14-10-2018 Tharo_2536 b9ac668528a9c7da87a33cadc96e0cd0 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 168 1.5E-10 T 14-10-2018 Tharo_0641 933fb3e4ed75e08eefe7045c54f724a5 131 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 7 111 32.583 T 14-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 Tharo_0641 933fb3e4ed75e08eefe7045c54f724a5 131 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 56 111 4.0E-24 T 14-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 Tharo_0641 933fb3e4ed75e08eefe7045c54f724a5 131 Gene3D G3DSA:3.10.20.400 2 98 1.8E-39 T 14-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 Tharo_0641 933fb3e4ed75e08eefe7045c54f724a5 131 SUPERFAMILY SSF141734 6 120 1.83E-49 T 14-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 Tharo_0641 933fb3e4ed75e08eefe7045c54f724a5 131 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 33 107 1.0E-35 T 14-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 Tharo_2663 1c37a5f0b8e2669a2e857843dc211b14 435 PIRSF PIRSF003095 1 435 1.1E-115 T 14-10-2018 IPR005215 Trigger factor GO:0015031 Tharo_2663 1c37a5f0b8e2669a2e857843dc211b14 435 Gene3D G3DSA:1.10.3120.10 116 418 1.2E-91 T 14-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 Tharo_2663 1c37a5f0b8e2669a2e857843dc211b14 435 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 156 237 2.0E-14 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain Tharo_2663 1c37a5f0b8e2669a2e857843dc211b14 435 Gene3D G3DSA:3.30.70.1050 1 115 1.9E-31 T 14-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 Tharo_2663 1c37a5f0b8e2669a2e857843dc211b14 435 Pfam PF05697 Bacterial trigger factor protein (TF) 1 142 1.8E-32 T 14-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 Tharo_2663 1c37a5f0b8e2669a2e857843dc211b14 435 Gene3D G3DSA:3.10.50.40 150 246 1.2E-91 T 14-10-2018 Tharo_2663 1c37a5f0b8e2669a2e857843dc211b14 435 Hamap MF_00303 Trigger factor [tig]. 1 420 19.481 T 14-10-2018 IPR005215 Trigger factor GO:0015031 Tharo_2663 1c37a5f0b8e2669a2e857843dc211b14 435 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 263 413 5.5E-30 T 14-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 Tharo_2663 1c37a5f0b8e2669a2e857843dc211b14 435 SUPERFAMILY SSF109998 248 431 2.88E-44 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily Tharo_2663 1c37a5f0b8e2669a2e857843dc211b14 435 TIGRFAM TIGR00115 tig: trigger factor 11 413 4.1E-130 T 14-10-2018 IPR005215 Trigger factor GO:0015031 Tharo_2663 1c37a5f0b8e2669a2e857843dc211b14 435 SUPERFAMILY SSF102735 1 129 3.27E-32 T 14-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 Tharo_2663 1c37a5f0b8e2669a2e857843dc211b14 435 SUPERFAMILY SSF54534 88 242 3.54E-33 T 14-10-2018 Tharo_0037 9e40cc6d8349bcf71afaa99c378c93c4 192 Pfam PF00924 Mechanosensitive ion channel 71 184 1.4E-13 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 Tharo_0037 9e40cc6d8349bcf71afaa99c378c93c4 192 SUPERFAMILY SSF50182 113 184 1.08E-9 T 14-10-2018 IPR010920 LSM domain superfamily Tharo_1771 940bef9bfb9c79a08c62c0cd7c41fd6a 337 Gene3D G3DSA:3.40.190.10 122 335 3.0E-121 T 14-10-2018 Tharo_1771 940bef9bfb9c79a08c62c0cd7c41fd6a 337 PIRSF PIRSF002825 5 337 1.7E-81 T 14-10-2018 IPR026045 Ferric binding protein Tharo_1771 940bef9bfb9c79a08c62c0cd7c41fd6a 337 SUPERFAMILY SSF53850 24 333 2.26E-77 T 14-10-2018 Tharo_1771 940bef9bfb9c79a08c62c0cd7c41fd6a 337 Gene3D G3DSA:3.40.190.10 26 299 3.0E-121 T 14-10-2018 Tharo_1771 940bef9bfb9c79a08c62c0cd7c41fd6a 337 Pfam PF13343 Bacterial extracellular solute-binding protein 71 304 2.2E-24 T 14-10-2018 Tharo_3151 f968defe21ca0a76d9bd41e8f35a072b 145 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 9 131 27.252 T 14-10-2018 IPR023006 Uncharacterised protein family UPF0225 Tharo_3151 f968defe21ca0a76d9bd41e8f35a072b 145 Gene3D G3DSA:3.10.450.50 11 133 1.1E-35 T 14-10-2018 Tharo_3151 f968defe21ca0a76d9bd41e8f35a072b 145 SUPERFAMILY SSF54427 32 132 3.07E-33 T 14-10-2018 IPR032710 NTF2-like domain superfamily Tharo_2939 2749eab9b2b4fc7ac7734cc0859f1aa4 391 SUPERFAMILY SSF54826 3 128 4.34E-27 T 14-10-2018 Tharo_2939 2749eab9b2b4fc7ac7734cc0859f1aa4 391 SMART SM00922 145 242 2.1E-27 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal Tharo_2939 2749eab9b2b4fc7ac7734cc0859f1aa4 391 Gene3D G3DSA:3.30.390.10 6 375 6.3E-119 T 14-10-2018 IPR029017 Enolase-like, N-terminal Tharo_2939 2749eab9b2b4fc7ac7734cc0859f1aa4 391 SUPERFAMILY SSF51604 115 376 4.19E-64 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Tharo_2939 2749eab9b2b4fc7ac7734cc0859f1aa4 391 Gene3D G3DSA:3.20.20.120 122 363 6.3E-119 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Tharo_2939 2749eab9b2b4fc7ac7734cc0859f1aa4 391 Pfam PF13378 Enolase C-terminal domain-like 149 374 1.3E-44 T 14-10-2018 IPR029065 Enolase C-terminal domain-like Tharo_2939 2749eab9b2b4fc7ac7734cc0859f1aa4 391 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 6 127 1.4E-18 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain Tharo_2939 2749eab9b2b4fc7ac7734cc0859f1aa4 391 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 192 223 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 Tharo_0056 786029d833b70903d2e9747b4849d092 348 SUPERFAMILY SSF54106 35 83 2.22E-6 T 14-10-2018 Tharo_0056 786029d833b70903d2e9747b4849d092 348 SMART SM00257 35 84 3.2E-4 T 14-10-2018 IPR018392 LysM domain Tharo_0056 786029d833b70903d2e9747b4849d092 348 Pfam PF01476 LysM domain 36 82 1.5E-12 T 14-10-2018 IPR018392 LysM domain Tharo_0056 786029d833b70903d2e9747b4849d092 348 Gene3D G3DSA:3.10.350.10 34 81 1.1E-14 T 14-10-2018 IPR036779 LysM domain superfamily Tharo_0336 a532f883f863c9b10525495b424dd90f 230 Hamap MF_00415 Flagellar L-ring protein [flgH]. 9 228 26.334 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 Tharo_0336 a532f883f863c9b10525495b424dd90f 230 Pfam PF02107 Flagellar L-ring protein 51 229 2.1E-60 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 Tharo_0336 a532f883f863c9b10525495b424dd90f 230 PRINTS PR01008 Flagellar L-ring protein signature 207 221 6.2E-28 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 Tharo_0336 a532f883f863c9b10525495b424dd90f 230 PRINTS PR01008 Flagellar L-ring protein signature 74 86 6.2E-28 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 Tharo_0336 a532f883f863c9b10525495b424dd90f 230 PRINTS PR01008 Flagellar L-ring protein signature 191 205 6.2E-28 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 Tharo_0336 a532f883f863c9b10525495b424dd90f 230 PRINTS PR01008 Flagellar L-ring protein signature 170 186 6.2E-28 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 Tharo_0336 a532f883f863c9b10525495b424dd90f 230 PRINTS PR01008 Flagellar L-ring protein signature 144 159 6.2E-28 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 Tharo_2465 2dc5685588b6572b0ea1dfe1436cb0c4 534 SMART SM00421 1 58 2.1E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2465 2dc5685588b6572b0ea1dfe1436cb0c4 534 SUPERFAMILY SSF46894 2 57 1.36E-15 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_2465 2dc5685588b6572b0ea1dfe1436cb0c4 534 SUPERFAMILY SSF52540 240 441 6.67E-14 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2465 2dc5685588b6572b0ea1dfe1436cb0c4 534 ProSitePatterns PS00622 LuxR-type HTH domain signature. 18 45 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2465 2dc5685588b6572b0ea1dfe1436cb0c4 534 Pfam PF00196 Bacterial regulatory proteins, luxR family 4 55 9.0E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2465 2dc5685588b6572b0ea1dfe1436cb0c4 534 Gene3D G3DSA:3.40.50.300 249 404 6.3E-6 T 14-10-2018 Tharo_2465 2dc5685588b6572b0ea1dfe1436cb0c4 534 Gene3D G3DSA:1.10.10.10 2 69 3.4E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2465 2dc5685588b6572b0ea1dfe1436cb0c4 534 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 4 18 1.5E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2465 2dc5685588b6572b0ea1dfe1436cb0c4 534 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 34 46 1.5E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2465 2dc5685588b6572b0ea1dfe1436cb0c4 534 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 18 34 1.5E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_1106 ca8df05b79476fb5502b0e8f43e09264 340 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 28 312 1.5E-57 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 Tharo_1106 ca8df05b79476fb5502b0e8f43e09264 340 SUPERFAMILY SSF53850 18 257 1.11E-5 T 14-10-2018 Tharo_1106 ca8df05b79476fb5502b0e8f43e09264 340 Gene3D G3DSA:3.40.190.170 22 340 9.0E-109 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily Tharo_0693 9db56c7823f54bbd352b12e5af63c710 315 TIGRFAM TIGR03756 conj_TIGR03756: integrating conjugative element protein, PFL_4710 family 29 313 4.6E-131 T 14-10-2018 IPR026331 Integrating conjugative element protein PFL_4710 Tharo_0693 9db56c7823f54bbd352b12e5af63c710 315 Pfam PF06834 TraU protein 37 303 1.9E-73 T 14-10-2018 IPR009649 TraU Tharo_3163 52731df3d4e03669e88a4736835539cf 178 SUPERFAMILY SSF49503 70 175 6.63E-25 T 14-10-2018 IPR008972 Cupredoxin Tharo_3163 52731df3d4e03669e88a4736835539cf 178 Gene3D G3DSA:2.60.40.420 66 175 7.6E-28 T 14-10-2018 IPR008972 Cupredoxin Tharo_3163 52731df3d4e03669e88a4736835539cf 178 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 105 168 2.9E-5 T 14-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_2961 c0e0d017df6c15772b082ae375ab253f 298 Pfam PF01136 Peptidase family U32 92 267 5.4E-13 T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 Tharo_1646 2b3321d2cb44c35416af1ac0c27a4862 465 Pfam PF05940 NnrS protein 41 437 3.6E-78 T 14-10-2018 IPR010266 NnrS Tharo_1068 b7919e0515f99506871bf1442989e603 249 SUPERFAMILY SSF53218 1 197 2.75E-30 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily Tharo_1068 b7919e0515f99506871bf1442989e603 249 Gene3D G3DSA:3.40.980.10 2 161 1.0E-36 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily Tharo_1068 b7919e0515f99506871bf1442989e603 249 Pfam PF00994 Probable molybdopterin binding domain 5 157 2.3E-24 T 14-10-2018 IPR001453 MoaB/Mog domain Tharo_1068 b7919e0515f99506871bf1442989e603 249 SMART SM00852 4 164 7.5E-27 T 14-10-2018 IPR001453 MoaB/Mog domain Tharo_0845 c17d29a42d32649d174693bd75722527 612 Pfam PF13522 Glutamine amidotransferase domain 63 182 2.6E-19 T 14-10-2018 Tharo_0845 c17d29a42d32649d174693bd75722527 612 Gene3D G3DSA:3.40.50.10490 251 611 8.0E-143 T 14-10-2018 Tharo_0845 c17d29a42d32649d174693bd75722527 612 Gene3D G3DSA:3.40.50.10490 450 597 8.0E-143 T 14-10-2018 Tharo_0845 c17d29a42d32649d174693bd75722527 612 SUPERFAMILY SSF56235 2 234 2.66E-66 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Tharo_0845 c17d29a42d32649d174693bd75722527 612 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 612 3.4E-245 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 Tharo_0845 c17d29a42d32649d174693bd75722527 612 Gene3D G3DSA:3.60.20.10 2 242 2.8E-71 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Tharo_0845 c17d29a42d32649d174693bd75722527 612 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 612 39.179 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 Tharo_0845 c17d29a42d32649d174693bd75722527 612 Pfam PF01380 SIS domain 465 594 4.6E-27 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Tharo_0845 c17d29a42d32649d174693bd75722527 612 Pfam PF01380 SIS domain 296 420 6.8E-33 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Tharo_0845 c17d29a42d32649d174693bd75722527 612 SUPERFAMILY SSF53697 247 612 2.41E-111 T 14-10-2018 Tharo_1722 66bd5d22c03836d878788abdb87ee445 496 Gene3D G3DSA:1.10.3720.10 264 493 2.2E-20 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_1722 66bd5d22c03836d878788abdb87ee445 496 SUPERFAMILY SSF161098 276 476 1.19E-16 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_1722 66bd5d22c03836d878788abdb87ee445 496 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 294 495 1.8E-23 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Tharo_1463 0702830d325fe5d47bcfdd088441ccc4 252 Pfam PF03695 Uncharacterised protein family (UPF0149) 25 202 6.5E-27 T 14-10-2018 IPR011978 Uncharacterised protein family UPF0149 Tharo_1463 0702830d325fe5d47bcfdd088441ccc4 252 Pfam PF02810 SEC-C motif 227 244 6.9E-11 T 14-10-2018 IPR004027 SEC-C motif Tharo_1463 0702830d325fe5d47bcfdd088441ccc4 252 SUPERFAMILY SSF103642 225 244 8.83E-8 T 14-10-2018 Tharo_1463 0702830d325fe5d47bcfdd088441ccc4 252 TIGRFAM TIGR02292 ygfB_yecA: yecA family protein 25 201 4.2E-28 T 14-10-2018 IPR011978 Uncharacterised protein family UPF0149 Tharo_1463 0702830d325fe5d47bcfdd088441ccc4 252 SUPERFAMILY SSF101327 23 154 7.72E-18 T 14-10-2018 IPR036255 YgfB-like superfamily Tharo_1463 0702830d325fe5d47bcfdd088441ccc4 252 Gene3D G3DSA:3.10.450.50 201 246 1.4E-9 T 14-10-2018 Tharo_0587 d83dea2754fbbe55fcd9c8fb43677359 804 Pfam PF07728 AAA domain (dynein-related subfamily) 497 650 3.1E-5 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 Tharo_0587 d83dea2754fbbe55fcd9c8fb43677359 804 SUPERFAMILY SSF52540 490 657 1.99E-14 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0587 d83dea2754fbbe55fcd9c8fb43677359 804 Gene3D G3DSA:3.40.50.300 480 665 1.7E-19 T 14-10-2018 Tharo_0494 13d5240e7592c7d77386651ca09f4579 635 Pfam PF00773 RNB domain 242 467 2.5E-32 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 Tharo_0494 13d5240e7592c7d77386651ca09f4579 635 Pfam PF00773 RNB domain 474 513 1.0E-7 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 Tharo_0494 13d5240e7592c7d77386651ca09f4579 635 SUPERFAMILY SSF50249 215 559 5.48E-75 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_0494 13d5240e7592c7d77386651ca09f4579 635 SMART SM00955 235 514 5.1E-63 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 Tharo_0628 206f8d2a8a14236df7c4b15bc9b7f5be 97 Pfam PF13466 STAS domain 14 88 3.2E-19 T 14-10-2018 IPR002645 STAS domain Tharo_0628 206f8d2a8a14236df7c4b15bc9b7f5be 97 SUPERFAMILY SSF52091 10 92 5.69E-14 T 14-10-2018 IPR036513 STAS domain superfamily Tharo_0628 206f8d2a8a14236df7c4b15bc9b7f5be 97 Gene3D G3DSA:3.30.750.24 4 97 2.4E-14 T 14-10-2018 IPR036513 STAS domain superfamily Tharo_2421 19ab4148abda616ed0ec64696ecc67b1 115 Pfam PF11604 Copper binding periplasmic protein CusF 47 112 3.3E-27 T 14-10-2018 IPR021647 Copper binding periplasmic protein CusF Tharo_2421 19ab4148abda616ed0ec64696ecc67b1 115 Gene3D G3DSA:2.40.50.320 43 115 2.9E-24 T 14-10-2018 Tharo_3357 bbc92e790ce8721a57b79ba3155c4d32 162 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 37 128 7.6E-16 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 Tharo_3357 bbc92e790ce8721a57b79ba3155c4d32 162 Gene3D G3DSA:2.30.110.10 28 148 6.2E-26 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 Tharo_3357 bbc92e790ce8721a57b79ba3155c4d32 162 SUPERFAMILY SSF50475 27 138 2.36E-16 T 14-10-2018 Tharo_0932 76b8d3c5ff93510352dd1d83e04b8147 609 Gene3D G3DSA:3.40.50.2000 1 181 4.9E-28 T 14-10-2018 Tharo_0932 76b8d3c5ff93510352dd1d83e04b8147 609 Pfam PF13579 Glycosyl transferase 4-like domain 15 155 1.7E-17 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Tharo_0932 76b8d3c5ff93510352dd1d83e04b8147 609 Gene3D G3DSA:3.40.50.2000 184 356 3.2E-36 T 14-10-2018 Tharo_0932 76b8d3c5ff93510352dd1d83e04b8147 609 Gene3D G3DSA:3.90.550.10 387 601 5.4E-33 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_0932 76b8d3c5ff93510352dd1d83e04b8147 609 SUPERFAMILY SSF53756 1 375 2.55E-66 T 14-10-2018 Tharo_0932 76b8d3c5ff93510352dd1d83e04b8147 609 Pfam PF00535 Glycosyl transferase family 2 388 520 4.4E-17 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Tharo_0932 76b8d3c5ff93510352dd1d83e04b8147 609 Pfam PF00534 Glycosyl transferases group 1 191 353 1.8E-23 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 Tharo_0932 76b8d3c5ff93510352dd1d83e04b8147 609 SUPERFAMILY SSF53448 388 605 1.37E-30 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_1675 74df47bb618b6595ae291c9ccff34b4e 572 Pfam PF01471 Putative peptidoglycan binding domain 237 291 8.6E-9 T 14-10-2018 IPR002477 Peptidoglycan binding-like Tharo_1675 74df47bb618b6595ae291c9ccff34b4e 572 Pfam PF03734 L,D-transpeptidase catalytic domain 324 484 5.3E-24 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 Tharo_1675 74df47bb618b6595ae291c9ccff34b4e 572 SUPERFAMILY SSF47090 219 298 1.8E-14 T 14-10-2018 IPR036365 PGBD-like superfamily Tharo_1675 74df47bb618b6595ae291c9ccff34b4e 572 SUPERFAMILY SSF141523 319 475 1.7E-13 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like Tharo_1441 a67be2334d2aa4f05f53ca8ecbb66450 337 Pfam PF01136 Peptidase family U32 82 336 2.1E-64 T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 Tharo_1187 e49b3150d912f67bf18eb043ab854ee0 265 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 244 34.444 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_1187 e49b3150d912f67bf18eb043ab854ee0 265 Gene3D G3DSA:3.30.70.580 1 105 6.2E-36 T 14-10-2018 Tharo_1187 e49b3150d912f67bf18eb043ab854ee0 265 PIRSF PIRSF001430 1 255 8.6E-76 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_1187 e49b3150d912f67bf18eb043ab854ee0 265 Gene3D G3DSA:3.30.70.660 106 243 5.0E-48 T 14-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 Tharo_1187 e49b3150d912f67bf18eb043ab854ee0 265 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 3 239 3.7E-64 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_1187 e49b3150d912f67bf18eb043ab854ee0 265 SUPERFAMILY SSF55120 1 251 1.87E-89 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_1187 e49b3150d912f67bf18eb043ab854ee0 265 Pfam PF01416 tRNA pseudouridine synthase 9 103 2.4E-8 T 14-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_1187 e49b3150d912f67bf18eb043ab854ee0 265 Pfam PF01416 tRNA pseudouridine synthase 143 245 7.4E-30 T 14-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_0883 ff598c420370db76394faf21f84885d5 139 SMART SM00748 12 118 9.9E-4 T 14-10-2018 IPR007842 HEPN domain Tharo_0883 ff598c420370db76394faf21f84885d5 139 Gene3D G3DSA:1.20.120.330 7 133 9.5E-21 T 14-10-2018 Tharo_0883 ff598c420370db76394faf21f84885d5 139 SUPERFAMILY SSF81593 37 128 3.81E-14 T 14-10-2018 Tharo_0883 ff598c420370db76394faf21f84885d5 139 Pfam PF05168 HEPN domain 37 127 5.2E-17 T 14-10-2018 IPR007842 HEPN domain Tharo_1668 9d5002fb0e71b2f5a7309754ad9d1900 482 Pfam PF01212 Beta-eliminating lyase 55 426 3.1E-55 T 14-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 Tharo_1668 9d5002fb0e71b2f5a7309754ad9d1900 482 PIRSF PIRSF001386 9 464 1.7E-187 T 14-10-2018 IPR011166 Beta-eliminating lyase family GO:0009072|GO:0016830 KEGG: 00380+4.1.99.1 Tharo_1668 9d5002fb0e71b2f5a7309754ad9d1900 482 Gene3D G3DSA:3.40.640.10 67 318 3.2E-162 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_1668 9d5002fb0e71b2f5a7309754ad9d1900 482 SUPERFAMILY SSF53383 12 463 1.46E-113 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_1668 9d5002fb0e71b2f5a7309754ad9d1900 482 Gene3D G3DSA:3.90.1150.10 15 457 3.2E-162 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_2561 45c271a4668763ec8afdeb9f750a75f7 130 SUPERFAMILY SSF55298 4 129 1.21E-32 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 Tharo_2561 45c271a4668763ec8afdeb9f750a75f7 130 Pfam PF01042 Endoribonuclease L-PSP 13 127 8.1E-23 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 Tharo_2561 45c271a4668763ec8afdeb9f750a75f7 130 Gene3D G3DSA:3.30.1330.40 9 130 1.2E-29 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 Tharo_2920 16915c8625a91acd0f108d8363c3cc22 495 Gene3D G3DSA:3.20.20.70 2 468 2.5E-102 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_2920 16915c8625a91acd0f108d8363c3cc22 495 SUPERFAMILY SSF51569 3 302 8.61E-50 T 14-10-2018 Tharo_2920 16915c8625a91acd0f108d8363c3cc22 495 Pfam PF02436 Conserved carboxylase domain 297 437 4.2E-24 T 14-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 Tharo_2920 16915c8625a91acd0f108d8363c3cc22 495 SUPERFAMILY SSF89000 302 439 7.06E-31 T 14-10-2018 Tharo_2920 16915c8625a91acd0f108d8363c3cc22 495 Pfam PF00682 HMGL-like 4 272 5.9E-20 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Tharo_2583 41c890336a8d0e2ae599088f49e24bb2 488 SUPERFAMILY SSF52540 78 360 7.54E-76 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2583 41c890336a8d0e2ae599088f49e24bb2 488 SMART SM00490 261 342 8.5E-34 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_2583 41c890336a8d0e2ae599088f49e24bb2 488 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 156 164 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site Tharo_2583 41c890336a8d0e2ae599088f49e24bb2 488 SMART SM00487 20 225 2.1E-65 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Tharo_2583 41c890336a8d0e2ae599088f49e24bb2 488 Pfam PF00270 DEAD/DEAH box helicase 25 199 8.6E-52 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Tharo_2583 41c890336a8d0e2ae599088f49e24bb2 488 Pfam PF00271 Helicase conserved C-terminal domain 236 342 5.3E-29 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_2583 41c890336a8d0e2ae599088f49e24bb2 488 Gene3D G3DSA:3.40.50.300 1 213 1.3E-81 T 14-10-2018 Tharo_2583 41c890336a8d0e2ae599088f49e24bb2 488 Gene3D G3DSA:3.40.50.300 219 396 3.3E-51 T 14-10-2018 Tharo_2763 9453429f2aa640cac6e281574b439634 144 Pfam PF00072 Response regulator receiver domain 11 123 7.9E-13 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2763 9453429f2aa640cac6e281574b439634 144 SUPERFAMILY SSF52172 7 129 8.54E-19 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_2763 9453429f2aa640cac6e281574b439634 144 SMART SM00448 9 123 1.4E-14 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2763 9453429f2aa640cac6e281574b439634 144 Gene3D G3DSA:3.40.50.12740 9 137 2.1E-18 T 14-10-2018 Tharo_3291 e343190a72a3119193ba8f09773fc065 400 Gene3D G3DSA:1.10.645.10 212 378 8.0E-15 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_3291 e343190a72a3119193ba8f09773fc065 400 SUPERFAMILY SSF56762 58 350 2.22E-22 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_3400 687763b0e22aa27c8db3fe504f492994 451 SUPERFAMILY SSF52540 77 372 4.67E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3400 687763b0e22aa27c8db3fe504f492994 451 Gene3D G3DSA:3.30.1360.120 2 125 1.6E-43 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 Tharo_3400 687763b0e22aa27c8db3fe504f492994 451 PRINTS PR00449 Transforming protein P21 ras signature 221 242 4.7E-5 T 14-10-2018 Tharo_3400 687763b0e22aa27c8db3fe504f492994 451 PRINTS PR00449 Transforming protein P21 ras signature 326 339 4.7E-5 T 14-10-2018 Tharo_3400 687763b0e22aa27c8db3fe504f492994 451 PRINTS PR00449 Transforming protein P21 ras signature 261 283 4.7E-5 T 14-10-2018 Tharo_3400 687763b0e22aa27c8db3fe504f492994 451 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 10 451 33.364 T 14-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 Tharo_3400 687763b0e22aa27c8db3fe504f492994 451 SUPERFAMILY SSF116878 125 451 3.79E-48 T 14-10-2018 Tharo_3400 687763b0e22aa27c8db3fe504f492994 451 Gene3D G3DSA:3.40.50.300 221 382 1.2E-99 T 14-10-2018 Tharo_3400 687763b0e22aa27c8db3fe504f492994 451 Pfam PF01926 50S ribosome-binding GTPase 222 313 6.1E-23 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_3400 687763b0e22aa27c8db3fe504f492994 451 Gene3D G3DSA:1.20.120.430 126 451 1.2E-99 T 14-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 Tharo_3400 687763b0e22aa27c8db3fe504f492994 451 Pfam PF10396 GTP-binding protein TrmE N-terminus 11 124 9.6E-39 T 14-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 Tharo_3400 687763b0e22aa27c8db3fe504f492994 451 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 16 451 1.4E-103 T 14-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 Tharo_3400 687763b0e22aa27c8db3fe504f492994 451 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 221 351 7.3E-22 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Tharo_3400 687763b0e22aa27c8db3fe504f492994 451 Pfam PF12631 MnmE helical domain 127 448 8.5E-57 T 14-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 Tharo_1756 13f98ca732d44fb997e9a7c24e34d4de 637 SUPERFAMILY SSF53300 452 628 3.24E-18 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Tharo_1756 13f98ca732d44fb997e9a7c24e34d4de 637 Gene3D G3DSA:3.40.50.410 448 606 2.4E-13 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Tharo_1756 13f98ca732d44fb997e9a7c24e34d4de 637 SMART SM00327 446 629 1.2E-14 T 14-10-2018 IPR002035 von Willebrand factor, type A Tharo_0513 e62eaf6bafbb0ab1477a3d93bb2ed562 354 Gene3D G3DSA:2.40.40.10 12 347 5.3E-126 T 14-10-2018 IPR036908 RlpA-like domain superfamily Tharo_0513 e62eaf6bafbb0ab1477a3d93bb2ed562 354 Gene3D G3DSA:2.40.240.50 92 257 5.3E-126 T 14-10-2018 Tharo_0513 e62eaf6bafbb0ab1477a3d93bb2ed562 354 SMART SM00925 93 250 6.7E-84 T 14-10-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 Tharo_0513 e62eaf6bafbb0ab1477a3d93bb2ed562 354 Pfam PF03562 MltA specific insert domain 18 250 2.4E-84 T 14-10-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 Tharo_0513 e62eaf6bafbb0ab1477a3d93bb2ed562 354 SUPERFAMILY SSF50685 4 351 3.17E-135 T 14-10-2018 IPR036908 RlpA-like domain superfamily Tharo_0513 e62eaf6bafbb0ab1477a3d93bb2ed562 354 PIRSF PIRSF019422 2 353 1.2E-136 T 14-10-2018 IPR026044 Membrane-bound lytic murein transglycosylase A Tharo_0513 e62eaf6bafbb0ab1477a3d93bb2ed562 354 Pfam PF06725 3D domain 271 344 7.0E-26 T 14-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 Tharo_1375 a5f2dcbf9633839afb56503b45f7670b 166 SUPERFAMILY SSF46785 3 134 3.96E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_1375 a5f2dcbf9633839afb56503b45f7670b 166 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 3 132 1.5E-25 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type Tharo_1375 a5f2dcbf9633839afb56503b45f7670b 166 Gene3D G3DSA:1.10.10.10 1 143 1.7E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1375 a5f2dcbf9633839afb56503b45f7670b 166 TIGRFAM TIGR02944 suf_reg_Xantho: FeS assembly SUF system regulator 1 131 4.8E-44 T 14-10-2018 IPR014290 SUF system FeS cluster assembly regulator Tharo_1375 a5f2dcbf9633839afb56503b45f7670b 166 Pfam PF02082 Transcriptional regulator 3 83 8.9E-20 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type Tharo_1302 df60e931be74d7ce8cacd8730ced9832 368 Gene3D G3DSA:3.90.180.10 34 358 1.2E-70 T 14-10-2018 Tharo_1302 df60e931be74d7ce8cacd8730ced9832 368 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 43 149 8.5E-27 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Tharo_1302 df60e931be74d7ce8cacd8730ced9832 368 TIGRFAM TIGR03201 dearomat_had: 6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase 20 368 9.4E-205 T 14-10-2018 IPR017614 6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase KEGG: 00362+1.1.1.368|MetaCyc: PWY-7401 Tharo_1302 df60e931be74d7ce8cacd8730ced9832 368 SUPERFAMILY SSF50129 23 193 1.89E-32 T 14-10-2018 IPR011032 GroES-like superfamily Tharo_1302 df60e931be74d7ce8cacd8730ced9832 368 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 77 91 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 Tharo_1302 df60e931be74d7ce8cacd8730ced9832 368 Pfam PF00107 Zinc-binding dehydrogenase 196 330 4.6E-22 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Tharo_1302 df60e931be74d7ce8cacd8730ced9832 368 SUPERFAMILY SSF51735 160 335 8.12E-27 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1302 df60e931be74d7ce8cacd8730ced9832 368 Gene3D G3DSA:3.40.50.720 170 315 1.2E-70 T 14-10-2018 Tharo_0984 d61e8c5efa9a868f428c02b9d99f28e1 236 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 21 174 9.7E-21 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ Tharo_0802 0131ec99c18db3046c51e7078b1e9a7d 202 PIRSF PIRSF006102 1 202 8.7E-59 T 14-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 Tharo_0802 0131ec99c18db3046c51e7078b1e9a7d 202 Hamap MF_00429 Na(+)-translocating NADH-quinone reductase subunit E [nqrE]. 1 202 28.574 T 14-10-2018 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 Tharo_0802 0131ec99c18db3046c51e7078b1e9a7d 202 TIGRFAM TIGR01940 nqrE: NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit 2 201 9.6E-104 T 14-10-2018 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 Tharo_0802 0131ec99c18db3046c51e7078b1e9a7d 202 Pfam PF02508 Rnf-Nqr subunit, membrane protein 4 200 9.7E-56 T 14-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 Tharo_1113 b64c3270686008c513aca99c3ac0f6de 402 SUPERFAMILY SSF51905 10 365 2.94E-60 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1113 b64c3270686008c513aca99c3ac0f6de 402 Gene3D G3DSA:3.30.9.30 44 363 5.3E-111 T 14-10-2018 Tharo_1113 b64c3270686008c513aca99c3ac0f6de 402 SUPERFAMILY SSF54373 184 283 8.04E-14 T 14-10-2018 Tharo_1113 b64c3270686008c513aca99c3ac0f6de 402 Pfam PF01494 FAD binding domain 11 350 3.7E-27 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 Tharo_1113 b64c3270686008c513aca99c3ac0f6de 402 Gene3D G3DSA:3.50.50.60 12 355 5.3E-111 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1113 b64c3270686008c513aca99c3ac0f6de 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 305 1.4E-14 T 14-10-2018 Tharo_1113 b64c3270686008c513aca99c3ac0f6de 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 159 174 1.4E-14 T 14-10-2018 Tharo_1113 b64c3270686008c513aca99c3ac0f6de 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 305 321 1.4E-14 T 14-10-2018 Tharo_1113 b64c3270686008c513aca99c3ac0f6de 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 11 33 1.4E-14 T 14-10-2018 Tharo_1069 81b3ac9df96fcc0ba880cfba4caadf19 257 Gene3D G3DSA:3.30.2010.10 149 238 7.9E-17 T 14-10-2018 Tharo_1069 81b3ac9df96fcc0ba880cfba4caadf19 257 Pfam PF01863 Protein of unknown function DUF45 35 235 3.7E-51 T 14-10-2018 IPR002725 Protein of unknown function DUF45 Tharo_0331 5c97b14bedd8123afc2fb09766e309fd 134 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 132 1.4E-52 T 14-10-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 Tharo_0331 5c97b14bedd8123afc2fb09766e309fd 134 Pfam PF00460 Flagella basal body rod protein 7 37 1.3E-9 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 Tharo_0331 5c97b14bedd8123afc2fb09766e309fd 134 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 14-10-2018 IPR019776 Flagellar basal body rod protein, conserved site Tharo_0331 5c97b14bedd8123afc2fb09766e309fd 134 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 87 130 4.5E-14 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain Tharo_0290 df5e05d2f6f338aff61d5fd8637e8bbc 421 Gene3D G3DSA:3.40.640.10 37 290 3.4E-179 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_0290 df5e05d2f6f338aff61d5fd8637e8bbc 421 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 421 51.269 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Tharo_0290 df5e05d2f6f338aff61d5fd8637e8bbc 421 PIRSF PIRSF000412 1 421 1.7E-162 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Tharo_0290 df5e05d2f6f338aff61d5fd8637e8bbc 421 Pfam PF00464 Serine hydroxymethyltransferase 8 386 2.9E-169 T 14-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Tharo_0290 df5e05d2f6f338aff61d5fd8637e8bbc 421 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 222 238 - T 14-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Tharo_0290 df5e05d2f6f338aff61d5fd8637e8bbc 421 SUPERFAMILY SSF53383 6 420 4.96E-172 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_0290 df5e05d2f6f338aff61d5fd8637e8bbc 421 Gene3D G3DSA:3.90.1150.10 10 396 3.4E-179 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_2312 7c001b0cce4e05be6c1b3a89e26a84a6 141 ProSitePatterns PS00893 Nudix box signature. 40 61 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Tharo_2312 7c001b0cce4e05be6c1b3a89e26a84a6 141 Gene3D G3DSA:3.90.79.10 7 130 3.3E-29 T 14-10-2018 Tharo_2312 7c001b0cce4e05be6c1b3a89e26a84a6 141 SUPERFAMILY SSF55811 6 128 2.84E-27 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Tharo_2312 7c001b0cce4e05be6c1b3a89e26a84a6 141 Pfam PF00293 NUDIX domain 12 119 2.0E-19 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Tharo_0162 84355415f57e650f85ce7896ef171eae 163 SUPERFAMILY SSF88659 77 136 4.58E-11 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Tharo_0162 84355415f57e650f85ce7896ef171eae 163 SUPERFAMILY SSF88946 1 69 9.42E-10 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Tharo_0162 84355415f57e650f85ce7896ef171eae 163 Pfam PF04542 Sigma-70 region 2 1 51 1.4E-9 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Tharo_0162 84355415f57e650f85ce7896ef171eae 163 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 2 131 3.2E-18 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Tharo_0162 84355415f57e650f85ce7896ef171eae 163 Gene3D G3DSA:1.10.10.10 53 139 2.4E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_0162 84355415f57e650f85ce7896ef171eae 163 Pfam PF08281 Sigma-70, region 4 83 134 6.0E-13 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Tharo_2625 49a1a734fada0550485b1caed6aafcfe 217 Gene3D G3DSA:3.40.50.2300 11 142 1.0E-47 T 14-10-2018 Tharo_2625 49a1a734fada0550485b1caed6aafcfe 217 Pfam PF00072 Response regulator receiver domain 17 126 7.0E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2625 49a1a734fada0550485b1caed6aafcfe 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2625 49a1a734fada0550485b1caed6aafcfe 217 Gene3D G3DSA:1.10.10.10 144 208 1.1E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2625 49a1a734fada0550485b1caed6aafcfe 217 SUPERFAMILY SSF46894 146 206 8.5E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_2625 49a1a734fada0550485b1caed6aafcfe 217 SMART SM00421 150 207 4.9E-23 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2625 49a1a734fada0550485b1caed6aafcfe 217 SUPERFAMILY SSF52172 17 166 6.12E-34 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_2625 49a1a734fada0550485b1caed6aafcfe 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 3.4E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2625 49a1a734fada0550485b1caed6aafcfe 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 3.4E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2625 49a1a734fada0550485b1caed6aafcfe 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 3.4E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2625 49a1a734fada0550485b1caed6aafcfe 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 206 4.9E-23 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2625 49a1a734fada0550485b1caed6aafcfe 217 SMART SM00448 15 126 3.7E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1120 efd79f5a89c83c6718ead45dd8e8304d 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 229 1.7E-37 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Tharo_1120 efd79f5a89c83c6718ead45dd8e8304d 258 SUPERFAMILY SSF52096 1 254 2.26E-65 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_1120 efd79f5a89c83c6718ead45dd8e8304d 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 100 120 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 Tharo_1120 efd79f5a89c83c6718ead45dd8e8304d 258 Gene3D G3DSA:3.90.226.10 1 201 1.9E-61 T 14-10-2018 Tharo_1120 efd79f5a89c83c6718ead45dd8e8304d 258 Gene3D G3DSA:1.10.12.10 202 256 2.6E-21 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal Tharo_2267 3a76f23984680c75ca42a10097fe9fbc 178 SUPERFAMILY SSF64438 10 163 5.31E-44 T 14-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic Tharo_2267 3a76f23984680c75ca42a10097fe9fbc 178 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 4 164 25.659 T 14-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 Tharo_2267 3a76f23984680c75ca42a10097fe9fbc 178 Pfam PF03975 CheD chemotactic sensory transduction 52 159 2.7E-28 T 14-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 Tharo_2267 3a76f23984680c75ca42a10097fe9fbc 178 Gene3D G3DSA:3.30.1330.200 7 167 1.1E-48 T 14-10-2018 IPR038592 CheD-like superfamily Tharo_1374 f5a96aefafab324147151e0ff14c854c 488 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 21 479 4.2E-194 T 14-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 Tharo_1374 f5a96aefafab324147151e0ff14c854c 488 Pfam PF01458 Uncharacterized protein family (UPF0051) 226 459 1.8E-68 T 14-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 Tharo_1374 f5a96aefafab324147151e0ff14c854c 488 SUPERFAMILY SSF101960 42 485 5.36E-138 T 14-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily Tharo_1752 c1e7f689fdb23b40e59f3b9610b69d32 402 Pfam PF13353 4Fe-4S single cluster domain 29 116 9.3E-9 T 14-10-2018 Tharo_1752 c1e7f689fdb23b40e59f3b9610b69d32 402 TIGRFAM TIGR04051 rSAM_NirJ: heme d1 biosynthesis radical SAM protein NirJ 25 378 7.9E-187 T 14-10-2018 IPR023992 Heme D1 biosynthesis, radical SAM protein NirJ Tharo_1752 c1e7f689fdb23b40e59f3b9610b69d32 402 PIRSF PIRSF037420 18 391 9.9E-133 T 14-10-2018 IPR017200 Coenzyme PQQ synthesis protein E Tharo_1752 c1e7f689fdb23b40e59f3b9610b69d32 402 SMART SM00729 26 228 0.008 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Tharo_1752 c1e7f689fdb23b40e59f3b9610b69d32 402 Pfam PF04055 Radical SAM superfamily 32 185 9.2E-20 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_1752 c1e7f689fdb23b40e59f3b9610b69d32 402 SUPERFAMILY SSF102114 23 350 7.06E-64 T 14-10-2018 Tharo_1752 c1e7f689fdb23b40e59f3b9610b69d32 402 Gene3D G3DSA:3.20.20.70 27 253 1.5E-46 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_0512 d27e3b5b8a2d7db2571f836d5b6ce911 244 SUPERFAMILY SSF54423 43 86 1.24E-6 T 14-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 Tharo_0512 d27e3b5b8a2d7db2571f836d5b6ce911 244 Pfam PF10411 Disulfide bond isomerase protein N-terminus 35 87 1.1E-14 T 14-10-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal Tharo_0512 d27e3b5b8a2d7db2571f836d5b6ce911 244 SUPERFAMILY SSF52833 95 241 1.02E-31 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_0512 d27e3b5b8a2d7db2571f836d5b6ce911 244 Pfam PF13098 Thioredoxin-like domain 116 239 4.7E-31 T 14-10-2018 IPR012336 Thioredoxin-like fold Tharo_0512 d27e3b5b8a2d7db2571f836d5b6ce911 244 Gene3D G3DSA:3.40.30.10 107 243 7.7E-34 T 14-10-2018 Tharo_0023 81454a9e71d136a4f7f0866f323dc518 334 SUPERFAMILY SSF56281 35 322 2.88E-55 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_0023 81454a9e71d136a4f7f0866f323dc518 334 Pfam PF00753 Metallo-beta-lactamase superfamily 92 299 6.0E-21 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_0023 81454a9e71d136a4f7f0866f323dc518 334 SMART SM00849 93 299 1.1E-24 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_0023 81454a9e71d136a4f7f0866f323dc518 334 Gene3D G3DSA:3.60.15.10 32 326 4.2E-103 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_2441 9b14f7784532383db7edc359443121f6 702 SUPERFAMILY SSF55486 19 697 5.25E-193 T 14-10-2018 Tharo_2441 9b14f7784532383db7edc359443121f6 702 Pfam PF01432 Peptidase family M3 238 697 2.5E-134 T 14-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 Tharo_2441 9b14f7784532383db7edc359443121f6 702 Gene3D G3DSA:1.10.1370.10 156 625 6.5E-252 T 14-10-2018 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 Tharo_2441 9b14f7784532383db7edc359443121f6 702 Gene3D G3DSA:1.10.1370.40 29 696 6.5E-252 T 14-10-2018 Tharo_2912 bf61d5a641fd66c245944c458b2aedf1 798 SUPERFAMILY SSF82866 208 398 1.7E-25 T 14-10-2018 Tharo_2912 bf61d5a641fd66c245944c458b2aedf1 798 Gene3D G3DSA:1.20.1640.10 593 798 6.4E-11 T 14-10-2018 Tharo_2912 bf61d5a641fd66c245944c458b2aedf1 798 Pfam PF03176 MMPL family 586 788 1.4E-12 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 Tharo_2912 bf61d5a641fd66c245944c458b2aedf1 798 Pfam PF03176 MMPL family 180 424 7.7E-8 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 Tharo_2912 bf61d5a641fd66c245944c458b2aedf1 798 SUPERFAMILY SSF82866 597 793 1.57E-30 T 14-10-2018 Tharo_1827 cb49283bda96a07890fab2603097f2ca 299 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 283 8.9E-34 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Tharo_1838 e8f27250164afaa0a74ef2f038558a70 142 Pfam PF08905 Domain of unknown function (DUF1850) 20 98 1.4E-23 T 14-10-2018 IPR015001 Protein of unknown function DUF1850 Tharo_3266 3ec05cbfcf792262a5b78531ab194a88 315 SUPERFAMILY SSF51735 4 309 1.48E-59 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_3266 3ec05cbfcf792262a5b78531ab194a88 315 Gene3D G3DSA:3.40.50.720 1 312 3.0E-56 T 14-10-2018 Tharo_3266 3ec05cbfcf792262a5b78531ab194a88 315 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 223 1.5E-27 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 Tharo_0113 b8fdde0cb8290ea34f9d462572904d59 145 Pfam PF00430 ATP synthase B/B' CF(0) 2 124 3.4E-25 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 Tharo_0113 b8fdde0cb8290ea34f9d462572904d59 145 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 126 9.839 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 Tharo_0113 b8fdde0cb8290ea34f9d462572904d59 145 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 2 143 1.3E-34 T 14-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 Tharo_1952 d30cabd1d7f3ef6ae384458701aedc83 233 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 10 229 3.0E-70 T 14-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 Tharo_1952 d30cabd1d7f3ef6ae384458701aedc83 233 Gene3D G3DSA:3.90.550.10 3 232 2.8E-76 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_1952 d30cabd1d7f3ef6ae384458701aedc83 233 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 108 115 - T 14-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 Tharo_1952 d30cabd1d7f3ef6ae384458701aedc83 233 SUPERFAMILY SSF53448 9 229 2.08E-60 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_1952 d30cabd1d7f3ef6ae384458701aedc83 233 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 10 227 9.0E-71 T 14-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 Tharo_1952 d30cabd1d7f3ef6ae384458701aedc83 233 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 7 228 42.381 T 14-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 Tharo_1377 04461e99f0cc2bcefa7e2dfbe72dc144 180 Pfam PF04116 Fatty acid hydroxylase superfamily 45 176 1.8E-18 T 14-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 Tharo_0560 1fc220ff6d50e2a26ee953b4dc0acf98 179 PIRSF PIRSF004553 3 178 5.0E-43 T 14-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 Tharo_0560 1fc220ff6d50e2a26ee953b4dc0acf98 179 Pfam PF03602 Conserved hypothetical protein 95 4 174 4.4E-48 T 14-10-2018 Tharo_0560 1fc220ff6d50e2a26ee953b4dc0acf98 179 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 3 176 2.2E-41 T 14-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 Tharo_0560 1fc220ff6d50e2a26ee953b4dc0acf98 179 Gene3D G3DSA:3.40.50.150 1 179 1.9E-54 T 14-10-2018 Tharo_0560 1fc220ff6d50e2a26ee953b4dc0acf98 179 SUPERFAMILY SSF53335 4 176 4.99E-46 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_1592 1312aec683cb71cac42570899eed536c 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 124 139 1.8E-20 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 Tharo_1592 1312aec683cb71cac42570899eed536c 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 81 96 1.8E-20 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 Tharo_1592 1312aec683cb71cac42570899eed536c 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 1.8E-20 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 Tharo_1592 1312aec683cb71cac42570899eed536c 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 47 63 1.8E-20 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 Tharo_1592 1312aec683cb71cac42570899eed536c 157 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 150 2.8E-36 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I Tharo_1592 1312aec683cb71cac42570899eed536c 157 Gene3D G3DSA:3.40.50.2300 1 156 9.1E-52 T 14-10-2018 Tharo_1592 1312aec683cb71cac42570899eed536c 157 SUPERFAMILY SSF52788 1 152 2.88E-47 T 14-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily Tharo_1592 1312aec683cb71cac42570899eed536c 157 SMART SM00226 2 152 1.4E-47 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I Tharo_3392 74e24ca11b1ad73ebb6cc5c0a55e3cd3 427 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 317 329 3.1E-24 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Tharo_3392 74e24ca11b1ad73ebb6cc5c0a55e3cd3 427 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 252 262 3.1E-24 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Tharo_3392 74e24ca11b1ad73ebb6cc5c0a55e3cd3 427 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 367 383 3.1E-24 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Tharo_3392 74e24ca11b1ad73ebb6cc5c0a55e3cd3 427 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 223 237 3.1E-24 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Tharo_3392 74e24ca11b1ad73ebb6cc5c0a55e3cd3 427 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 408 425 3.1E-24 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Tharo_3392 74e24ca11b1ad73ebb6cc5c0a55e3cd3 427 Gene3D G3DSA:1.10.940.10 10 145 5.3E-17 T 14-10-2018 IPR035926 NusB-like superfamily Tharo_3392 74e24ca11b1ad73ebb6cc5c0a55e3cd3 427 Gene3D G3DSA:3.40.50.150 232 426 8.4E-57 T 14-10-2018 Tharo_3392 74e24ca11b1ad73ebb6cc5c0a55e3cd3 427 Pfam PF01029 NusB family 43 129 5.2E-7 T 14-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 Tharo_3392 74e24ca11b1ad73ebb6cc5c0a55e3cd3 427 Gene3D G3DSA:3.30.70.1170 176 231 8.0E-11 T 14-10-2018 Tharo_3392 74e24ca11b1ad73ebb6cc5c0a55e3cd3 427 SUPERFAMILY SSF48013 18 152 4.09E-18 T 14-10-2018 IPR035926 NusB-like superfamily Tharo_3392 74e24ca11b1ad73ebb6cc5c0a55e3cd3 427 SUPERFAMILY SSF53335 144 425 1.02E-60 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_3392 74e24ca11b1ad73ebb6cc5c0a55e3cd3 427 Pfam PF01189 16S rRNA methyltransferase RsmB/F 242 424 3.7E-49 T 14-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 Tharo_3392 74e24ca11b1ad73ebb6cc5c0a55e3cd3 427 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 46 425 2.5E-89 T 14-10-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 Tharo_0674 ee6e43fffe75690d6784a6e0d63c9b52 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 186 1.2E-5 T 14-10-2018 Tharo_0674 ee6e43fffe75690d6784a6e0d63c9b52 248 SUPERFAMILY SSF51735 5 247 1.33E-76 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_0674 ee6e43fffe75690d6784a6e0d63c9b52 248 Gene3D G3DSA:3.40.50.720 2 247 7.3E-78 T 14-10-2018 Tharo_0674 ee6e43fffe75690d6784a6e0d63c9b52 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.1E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0674 ee6e43fffe75690d6784a6e0d63c9b52 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.1E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0674 ee6e43fffe75690d6784a6e0d63c9b52 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.1E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0674 ee6e43fffe75690d6784a6e0d63c9b52 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.1E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0674 ee6e43fffe75690d6784a6e0d63c9b52 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.1E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0674 ee6e43fffe75690d6784a6e0d63c9b52 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.1E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0674 ee6e43fffe75690d6784a6e0d63c9b52 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 246 1.8E-56 T 14-10-2018 Tharo_0674 ee6e43fffe75690d6784a6e0d63c9b52 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.7E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0674 ee6e43fffe75690d6784a6e0d63c9b52 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.7E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0674 ee6e43fffe75690d6784a6e0d63c9b52 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.7E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0674 ee6e43fffe75690d6784a6e0d63c9b52 248 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 6 247 2.6E-105 T 14-10-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216|MetaCyc: PWY-7948 Tharo_0674 ee6e43fffe75690d6784a6e0d63c9b52 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Tharo_1596 8aca17568aa26c24a0a153d8f7860368 246 Gene3D G3DSA:3.30.950.10 133 246 7.7E-44 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 Tharo_1596 8aca17568aa26c24a0a153d8f7860368 246 SUPERFAMILY SSF53790 11 244 4.19E-60 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Tharo_1596 8aca17568aa26c24a0a153d8f7860368 246 Gene3D G3DSA:3.40.1010.10 10 132 3.9E-37 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Tharo_1596 8aca17568aa26c24a0a153d8f7860368 246 PIRSF PIRSF005917 1 244 3.7E-45 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 Tharo_0864 77ace2a70afdea1a43eb8e4b018e3afa 302 SUPERFAMILY SSF53098 142 272 1.74E-7 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_0864 77ace2a70afdea1a43eb8e4b018e3afa 302 Pfam PF13358 DDE superfamily endonuclease 110 255 3.7E-24 T 14-10-2018 IPR038717 Tc1-like transposase, DDE domain Tharo_2676 9c6ab1ca464a82be0bb50c4cf4826653 356 Gene3D G3DSA:3.40.50.10470 187 350 9.3E-48 T 14-10-2018 Tharo_2676 9c6ab1ca464a82be0bb50c4cf4826653 356 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 12 343 1.9E-115 T 14-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 Tharo_2676 9c6ab1ca464a82be0bb50c4cf4826653 356 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 35 343 4.3E-83 T 14-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 Tharo_2676 9c6ab1ca464a82be0bb50c4cf4826653 356 Pfam PF01008 Initiation factor 2 subunit family 47 344 3.2E-55 T 14-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 Tharo_2676 9c6ab1ca464a82be0bb50c4cf4826653 356 Gene3D G3DSA:1.20.120.1840 6 186 8.6E-48 T 14-10-2018 Tharo_2676 9c6ab1ca464a82be0bb50c4cf4826653 356 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 5 354 35.088 T 14-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 Tharo_2676 9c6ab1ca464a82be0bb50c4cf4826653 356 SUPERFAMILY SSF100950 4 351 4.54E-101 T 14-10-2018 IPR037171 NagB/RpiA transferase-like Tharo_2373 096f099485cf21b70c3b47a2d2f1c9fe 357 Gene3D G3DSA:3.40.50.150 159 340 7.2E-27 T 14-10-2018 Tharo_2373 096f099485cf21b70c3b47a2d2f1c9fe 357 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 240 246 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Tharo_2373 096f099485cf21b70c3b47a2d2f1c9fe 357 Pfam PF05175 Methyltransferase small domain 175 288 2.2E-10 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 Tharo_2373 096f099485cf21b70c3b47a2d2f1c9fe 357 SUPERFAMILY SSF53335 135 289 4.93E-30 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_3081 da59b4ba2a5d33d524b783a397698aed 84 SUPERFAMILY SSF143011 1 83 1.05E-27 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_3081 da59b4ba2a5d33d524b783a397698aed 84 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 5 84 8.6E-40 T 14-10-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 Tharo_3081 da59b4ba2a5d33d524b783a397698aed 84 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 5 84 4.0E-35 T 14-10-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 Tharo_3081 da59b4ba2a5d33d524b783a397698aed 84 Gene3D G3DSA:3.30.2310.20 1 84 3.0E-40 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_3382 20b273795ba1ad4db4813ca94e96abb1 205 SUPERFAMILY SSF81452 17 204 1.18E-38 T 14-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_3382 20b273795ba1ad4db4813ca94e96abb1 205 Gene3D G3DSA:1.20.120.80 25 205 4.4E-35 T 14-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0255 e13b6b72aa68e53f1cab17cac535317d 62 Pfam PF11943 Protein of unknown function (DUF3460) 3 59 1.2E-27 T 14-10-2018 IPR021853 Protein of unknown function DUF3460 Tharo_2538 658609ca8911b72faffd45e4fdd41ea3 159 SUPERFAMILY SSF54862 3 137 8.37E-40 T 14-10-2018 Tharo_2538 658609ca8911b72faffd45e4fdd41ea3 159 Gene3D G3DSA:3.30.70.20 4 148 1.5E-24 T 14-10-2018 Tharo_2538 658609ca8911b72faffd45e4fdd41ea3 159 Pfam PF13247 4Fe-4S dicluster domain 49 134 7.1E-13 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_2538 658609ca8911b72faffd45e4fdd41ea3 159 Pfam PF00037 4Fe-4S binding domain 6 22 5.0E-5 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_2538 658609ca8911b72faffd45e4fdd41ea3 159 Gene3D G3DSA:3.30.70.20 59 112 1.5E-24 T 14-10-2018 Tharo_2538 658609ca8911b72faffd45e4fdd41ea3 159 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 86 97 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_3173 4efe02d2f29ccaa47a7c13672eb5bfb4 465 Pfam PF01926 50S ribosome-binding GTPase 9 155 8.9E-15 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 Tharo_3173 4efe02d2f29ccaa47a7c13672eb5bfb4 465 Pfam PF11981 Domain of unknown function (DUF3482) 168 461 3.2E-98 T 14-10-2018 IPR021871 Protein of unknown function DUF3482 Tharo_3173 4efe02d2f29ccaa47a7c13672eb5bfb4 465 SUPERFAMILY SSF52540 6 159 6.95E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3173 4efe02d2f29ccaa47a7c13672eb5bfb4 465 Gene3D G3DSA:3.40.50.300 5 199 3.8E-24 T 14-10-2018 Tharo_0354 67b360fb400b99ae5ae51c3100298ab1 555 Gene3D G3DSA:3.30.300.30 121 224 7.5E-12 T 14-10-2018 Tharo_0354 67b360fb400b99ae5ae51c3100298ab1 555 Pfam PF01514 Secretory protein of YscJ/FliF family 32 221 1.9E-68 T 14-10-2018 IPR006182 Secretory protein YscJ/FliF Tharo_0354 67b360fb400b99ae5ae51c3100298ab1 555 PRINTS PR01009 Flagellar M-ring protein signature 122 140 4.7E-34 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 Tharo_0354 67b360fb400b99ae5ae51c3100298ab1 555 PRINTS PR01009 Flagellar M-ring protein signature 266 284 4.7E-34 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 Tharo_0354 67b360fb400b99ae5ae51c3100298ab1 555 PRINTS PR01009 Flagellar M-ring protein signature 197 215 4.7E-34 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 Tharo_0354 67b360fb400b99ae5ae51c3100298ab1 555 PRINTS PR01009 Flagellar M-ring protein signature 154 168 4.7E-34 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 Tharo_0354 67b360fb400b99ae5ae51c3100298ab1 555 PRINTS PR01009 Flagellar M-ring protein signature 354 378 4.7E-34 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 Tharo_0354 67b360fb400b99ae5ae51c3100298ab1 555 PIRSF PIRSF004862 2 555 7.5E-149 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 Tharo_0354 67b360fb400b99ae5ae51c3100298ab1 555 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 16 553 8.1E-121 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 Tharo_0354 67b360fb400b99ae5ae51c3100298ab1 555 Pfam PF08345 Flagellar M-ring protein C-terminal 253 430 1.2E-43 T 14-10-2018 IPR013556 Flagellar M-ring C-terminal Tharo_1941 3917fc779f957532db4e95ca0003c494 95 Pfam PF08681 Protein of unknown function (DUF1778) 13 87 8.7E-27 T 14-10-2018 IPR014795 Vibrio phage ICP1, Orf50 Tharo_1941 3917fc779f957532db4e95ca0003c494 95 Gene3D G3DSA:1.20.5.780 8 89 1.9E-15 T 14-10-2018 Tharo_1941 3917fc779f957532db4e95ca0003c494 95 SUPERFAMILY SSF47598 9 86 5.34E-23 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Tharo_0568 599bd7960e2f4837ca20ab1a613ab75c 625 Pfam PF00664 ABC transporter transmembrane region 43 301 8.2E-10 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Tharo_0568 599bd7960e2f4837ca20ab1a613ab75c 625 SMART SM00382 390 581 1.7E-20 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0568 599bd7960e2f4837ca20ab1a613ab75c 625 Gene3D G3DSA:1.20.1560.10 33 349 1.4E-21 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Tharo_0568 599bd7960e2f4837ca20ab1a613ab75c 625 SUPERFAMILY SSF52540 351 605 1.09E-86 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0568 599bd7960e2f4837ca20ab1a613ab75c 625 ProSitePatterns PS00211 ABC transporters family signature. 507 521 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_0568 599bd7960e2f4837ca20ab1a613ab75c 625 Gene3D G3DSA:3.40.50.300 351 608 2.1E-89 T 14-10-2018 Tharo_0568 599bd7960e2f4837ca20ab1a613ab75c 625 SUPERFAMILY SSF90123 23 342 3.79E-46 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Tharo_0568 599bd7960e2f4837ca20ab1a613ab75c 625 Pfam PF00005 ABC transporter 382 535 2.1E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_2100 e9411014b5a729a71ce45504530e2aea 137 SUPERFAMILY SSF55729 17 126 1.02E-6 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Tharo_2774 55d0485a7a562f825f20595f9224ad6d 612 Pfam PF00391 PEP-utilising enzyme, mobile domain 534 605 7.3E-23 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 Tharo_2774 55d0485a7a562f825f20595f9224ad6d 612 Gene3D G3DSA:3.50.30.10 507 610 5.1E-32 T 14-10-2018 Tharo_2774 55d0485a7a562f825f20595f9224ad6d 612 SUPERFAMILY SSF52009 508 608 4.19E-29 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 Tharo_2337 55358ba1058b97f827f655a0066f3afa 206 Gene3D G3DSA:1.20.1260.10 38 196 8.6E-7 T 14-10-2018 IPR012347 Ferritin-like Tharo_2337 55358ba1058b97f827f655a0066f3afa 206 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 45 205 1.8E-41 T 14-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 Tharo_2337 55358ba1058b97f827f655a0066f3afa 206 SUPERFAMILY SSF47240 44 175 2.87E-18 T 14-10-2018 IPR009078 Ferritin-like superfamily Tharo_2337 55358ba1058b97f827f655a0066f3afa 206 Hamap MF_01658 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [coq7]. 6 206 30.317 T 14-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 Tharo_1500 1ac36406fdd000df70aecded530553aa 154 Gene3D G3DSA:3.40.140.10 1 152 4.3E-62 T 14-10-2018 Tharo_1500 1ac36406fdd000df70aecded530553aa 154 Pfam PF14437 MafB19-like deaminase 1 148 1.1E-32 T 14-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 Tharo_1500 1ac36406fdd000df70aecded530553aa 154 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 7 148 48.174 T 14-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 Tharo_1500 1ac36406fdd000df70aecded530553aa 154 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 52 89 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 Tharo_1500 1ac36406fdd000df70aecded530553aa 154 SUPERFAMILY SSF53927 2 148 1.09E-57 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Tharo_1856 e832f51a8963866f9ed1e2af1e2ce4b9 421 Pfam PF02321 Outer membrane efflux protein 247 417 8.7E-16 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Tharo_1856 e832f51a8963866f9ed1e2af1e2ce4b9 421 Pfam PF02321 Outer membrane efflux protein 41 217 2.2E-10 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Tharo_1856 e832f51a8963866f9ed1e2af1e2ce4b9 421 SUPERFAMILY SSF56954 7 420 7.85E-52 T 14-10-2018 Tharo_1856 e832f51a8963866f9ed1e2af1e2ce4b9 421 Gene3D G3DSA:1.20.1600.10 17 419 7.0E-51 T 14-10-2018 Tharo_1043 25204167c8388e90f1957a228ae9c829 226 Pfam PF01841 Transglutaminase-like superfamily 27 141 7.3E-14 T 14-10-2018 IPR002931 Transglutaminase-like Tharo_1043 25204167c8388e90f1957a228ae9c829 226 Gene3D G3DSA:3.10.620.30 1 165 2.1E-11 T 14-10-2018 Tharo_1043 25204167c8388e90f1957a228ae9c829 226 SUPERFAMILY SSF54001 16 172 4.91E-19 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily Tharo_2293 f28e1128a8452b0d457008085ca5206e 165 Pfam PF05751 FixH 11 150 1.5E-35 T 14-10-2018 IPR008620 Nitrogen fixation protein FixH Tharo_2931 acb3276261d358f10393816ecaa97668 254 Gene3D G3DSA:3.40.50.200 12 250 1.5E-26 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 Tharo_2931 acb3276261d358f10393816ecaa97668 254 Pfam PF00082 Subtilase family 65 148 1.1E-4 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Tharo_2931 acb3276261d358f10393816ecaa97668 254 SUPERFAMILY SSF52743 20 245 5.37E-26 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 Tharo_0788 715f27f9be50d218c781140b1ea6477c 259 Pfam PF01925 Sulfite exporter TauE/SafE 6 256 2.9E-44 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 Tharo_0218 58922c046148125686c02bd11e60fad5 83 SMART SM00966 9 54 4.5E-8 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Tharo_0218 58922c046148125686c02bd11e60fad5 83 SUPERFAMILY SSF89447 6 65 8.89E-14 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily Tharo_0218 58922c046148125686c02bd11e60fad5 83 Gene3D G3DSA:2.10.260.10 3 83 3.7E-20 T 14-10-2018 Tharo_0218 58922c046148125686c02bd11e60fad5 83 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 11 51 5.0E-8 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Tharo_0438 ad2eeb7050ea6fc92bc745a1facaf9d9 501 Gene3D G3DSA:3.40.50.300 4 141 3.6E-12 T 14-10-2018 Tharo_0438 ad2eeb7050ea6fc92bc745a1facaf9d9 501 Gene3D G3DSA:3.40.50.300 205 372 2.1E-21 T 14-10-2018 Tharo_0438 ad2eeb7050ea6fc92bc745a1facaf9d9 501 Pfam PF05872 Bacterial protein of unknown function (DUF853) 12 500 7.9E-238 T 14-10-2018 IPR033186 Helicase HerA-like C-terminal Tharo_0438 ad2eeb7050ea6fc92bc745a1facaf9d9 501 SMART SM00382 26 330 0.0047 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0438 ad2eeb7050ea6fc92bc745a1facaf9d9 501 SUPERFAMILY SSF52540 22 373 1.71E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1153 be31acac2865477487a3a0b63d5a66aa 250 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 36 248 2.0E-54 T 14-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase Tharo_1153 be31acac2865477487a3a0b63d5a66aa 250 Gene3D G3DSA:3.60.140.10 3 250 1.8E-91 T 14-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily Tharo_1153 be31acac2865477487a3a0b63d5a66aa 250 SUPERFAMILY SSF64438 6 249 4.76E-82 T 14-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic Tharo_1153 be31acac2865477487a3a0b63d5a66aa 250 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 27 247 3.8E-78 T 14-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase Tharo_1762 e04bcb0fdfe6fb216ddf994640e3c60c 365 SUPERFAMILY SSF51735 19 188 1.85E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1762 e04bcb0fdfe6fb216ddf994640e3c60c 365 SMART SM00846 18 172 4.1E-62 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1762 e04bcb0fdfe6fb216ddf994640e3c60c 365 Gene3D G3DSA:3.40.50.720 19 346 7.1E-114 T 14-10-2018 Tharo_1762 e04bcb0fdfe6fb216ddf994640e3c60c 365 PIRSF PIRSF000149 16 356 1.8E-121 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1762 e04bcb0fdfe6fb216ddf994640e3c60c 365 SUPERFAMILY SSF55347 172 335 8.33E-55 T 14-10-2018 Tharo_1762 e04bcb0fdfe6fb216ddf994640e3c60c 365 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 19 119 4.1E-28 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1762 e04bcb0fdfe6fb216ddf994640e3c60c 365 Gene3D G3DSA:3.30.360.10 171 336 7.1E-114 T 14-10-2018 Tharo_1762 e04bcb0fdfe6fb216ddf994640e3c60c 365 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 178 333 1.4E-46 T 14-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1762 e04bcb0fdfe6fb216ddf994640e3c60c 365 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 166 184 3.6E-19 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1762 e04bcb0fdfe6fb216ddf994640e3c60c 365 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 290 305 3.6E-19 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1762 e04bcb0fdfe6fb216ddf994640e3c60c 365 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 127 140 3.6E-19 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1762 e04bcb0fdfe6fb216ddf994640e3c60c 365 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 193 209 3.6E-19 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1762 e04bcb0fdfe6fb216ddf994640e3c60c 365 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 250 267 3.6E-19 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Tharo_1951 e1c273ddc071ec6ebc73ea53a1c5f0a6 274 Gene3D G3DSA:3.40.830.10 4 264 3.9E-59 T 14-10-2018 Tharo_1951 e1c273ddc071ec6ebc73ea53a1c5f0a6 274 Hamap MF_00055 MEMO1 family protein . 5 264 48.929 T 14-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 Tharo_1951 e1c273ddc071ec6ebc73ea53a1c5f0a6 274 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 7 263 1.1E-80 T 14-10-2018 Tharo_1951 e1c273ddc071ec6ebc73ea53a1c5f0a6 274 Pfam PF01875 Memo-like protein 9 261 4.8E-47 T 14-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 Tharo_0576 434d79c411297fbd58be486220b99a6d 92 Pfam PF14076 Domain of unknown function (DUF4258) 6 76 7.7E-18 T 14-10-2018 IPR025354 Protein of unknown function DUF4258 Tharo_2959 c7e9f97b23ab61b0c4a9fa1995c45a40 486 Gene3D G3DSA:1.20.1730.10 18 469 5.6E-67 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily Tharo_2959 c7e9f97b23ab61b0c4a9fa1995c45a40 486 Pfam PF00474 Sodium:solute symporter family 30 426 2.6E-33 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 Tharo_2959 c7e9f97b23ab61b0c4a9fa1995c45a40 486 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 408 428 - T 14-10-2018 IPR018212 Sodium/solute symporter, conserved site Tharo_1630 2bf1922f677fbf36b7155683bf5d2eb0 391 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 12 390 6.4E-117 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Tharo_1630 2bf1922f677fbf36b7155683bf5d2eb0 391 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 201 215 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Tharo_1630 2bf1922f677fbf36b7155683bf5d2eb0 391 Gene3D G3DSA:3.40.640.10 10 257 8.1E-73 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_1630 2bf1922f677fbf36b7155683bf5d2eb0 391 SUPERFAMILY SSF53383 25 390 3.81E-99 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_1630 2bf1922f677fbf36b7155683bf5d2eb0 391 PIRSF PIRSF001434 1 391 2.3E-130 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Tharo_1630 2bf1922f677fbf36b7155683bf5d2eb0 391 Gene3D G3DSA:3.90.1150.10 258 391 6.1E-53 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_1110 77cb13439f83f59437c5532acb8bcb5b 341 SUPERFAMILY SSF53850 125 269 1.26E-5 T 14-10-2018 Tharo_1110 77cb13439f83f59437c5532acb8bcb5b 341 Gene3D G3DSA:3.40.190.170 25 341 9.5E-107 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily Tharo_1110 77cb13439f83f59437c5532acb8bcb5b 341 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 30 316 2.8E-54 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 Tharo_3339 7681ed4f29705b05ffde82c4f4fa3af8 196 TIGRFAM TIGR02081 metW: methionine biosynthesis protein MetW 5 192 6.5E-73 T 14-10-2018 IPR010743 Methionine biosynthesis MetW KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 Tharo_3339 7681ed4f29705b05ffde82c4f4fa3af8 196 Pfam PF07021 Methionine biosynthesis protein MetW 5 192 1.2E-68 T 14-10-2018 IPR010743 Methionine biosynthesis MetW KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 Tharo_3339 7681ed4f29705b05ffde82c4f4fa3af8 196 Gene3D G3DSA:3.40.50.150 7 173 1.1E-21 T 14-10-2018 Tharo_3339 7681ed4f29705b05ffde82c4f4fa3af8 196 SUPERFAMILY SSF53335 7 166 4.8E-26 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_2851 8257606e65a8dede33fde83d7a3d7f06 107 Pfam PF11804 Protein of unknown function (DUF3325) 8 101 9.6E-14 T 14-10-2018 IPR021762 Protein of unknown function DUF3325 Tharo_0520 1e17dfafcc97ebdedba980507b12d8d8 454 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 21 429 38.724 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Tharo_0520 1e17dfafcc97ebdedba980507b12d8d8 454 SUPERFAMILY SSF53686 31 427 4.58E-109 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Tharo_0520 1e17dfafcc97ebdedba980507b12d8d8 454 PIRSF PIRSF001413 9 435 2.0E-112 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Tharo_0520 1e17dfafcc97ebdedba980507b12d8d8 454 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 76 416 1.0E-45 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Tharo_0520 1e17dfafcc97ebdedba980507b12d8d8 454 Gene3D G3DSA:3.40.50.1100 14 237 3.1E-168 T 14-10-2018 Tharo_0520 1e17dfafcc97ebdedba980507b12d8d8 454 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 104 118 - T 14-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Tharo_0520 1e17dfafcc97ebdedba980507b12d8d8 454 PIRSF PIRSF500824 1 438 2.9E-199 T 14-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Tharo_0520 1e17dfafcc97ebdedba980507b12d8d8 454 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 13 430 5.9E-190 T 14-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Tharo_0520 1e17dfafcc97ebdedba980507b12d8d8 454 Gene3D G3DSA:3.40.50.1100 13 422 3.1E-168 T 14-10-2018 Tharo_0900 1b2fcdcf9c2db205d9023dd710c7a87e 311 Gene3D G3DSA:3.40.1190.20 1 311 1.3E-112 T 14-10-2018 IPR029056 Ribokinase-like Tharo_0900 1b2fcdcf9c2db205d9023dd710c7a87e 311 Pfam PF00294 pfkB family carbohydrate kinase 33 292 1.3E-36 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB Tharo_0900 1b2fcdcf9c2db205d9023dd710c7a87e 311 SUPERFAMILY SSF53613 1 297 2.81E-65 T 14-10-2018 IPR029056 Ribokinase-like Tharo_0900 1b2fcdcf9c2db205d9023dd710c7a87e 311 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 47 71 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 Tharo_1178 1ddb491c4e2d37ff61d43f2c356c1c3f 386 Gene3D G3DSA:1.20.1250.20 188 378 2.3E-44 T 14-10-2018 Tharo_1178 1ddb491c4e2d37ff61d43f2c356c1c3f 386 SUPERFAMILY SSF103473 4 381 2.88E-49 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_1178 1ddb491c4e2d37ff61d43f2c356c1c3f 386 Pfam PF12832 MFS_1 like family 4 357 1.5E-80 T 14-10-2018 IPR024989 Major facilitator superfamily associated domain Tharo_1178 1ddb491c4e2d37ff61d43f2c356c1c3f 386 PIRSF PIRSF004925 1 386 9.8E-107 T 14-10-2018 IPR026032 Probable 3-phenylpropionic acid transporter Tharo_1178 1ddb491c4e2d37ff61d43f2c356c1c3f 386 Gene3D G3DSA:1.20.1250.20 3 185 4.4E-24 T 14-10-2018 Tharo_2068 91e9b411fbc829bf13f513bf7d0b0baa 273 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 175 193 - T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 Tharo_2068 91e9b411fbc829bf13f513bf7d0b0baa 273 SUPERFAMILY SSF55920 3 258 6.28E-89 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like Tharo_2068 91e9b411fbc829bf13f513bf7d0b0baa 273 Pfam PF00557 Metallopeptidase family M24 12 248 4.6E-52 T 14-10-2018 IPR000994 Peptidase M24 Tharo_2068 91e9b411fbc829bf13f513bf7d0b0baa 273 Hamap MF_01974 Methionine aminopeptidase [map]. 3 258 40.988 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 Tharo_2068 91e9b411fbc829bf13f513bf7d0b0baa 273 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 257 1.3E-93 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 Tharo_2068 91e9b411fbc829bf13f513bf7d0b0baa 273 Gene3D G3DSA:3.90.230.10 1 262 1.9E-109 T 14-10-2018 Tharo_2068 91e9b411fbc829bf13f513bf7d0b0baa 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 200 212 5.1E-23 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Tharo_2068 91e9b411fbc829bf13f513bf7d0b0baa 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 169 181 5.1E-23 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Tharo_2068 91e9b411fbc829bf13f513bf7d0b0baa 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 74 87 5.1E-23 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Tharo_2068 91e9b411fbc829bf13f513bf7d0b0baa 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 96 112 5.1E-23 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Tharo_2521 de970698edf55d033b82134de5315ccd 76 Pfam PF01206 Sulfurtransferase TusA 6 74 5.7E-23 T 14-10-2018 IPR001455 TusA-like domain Tharo_2521 de970698edf55d033b82134de5315ccd 76 Gene3D G3DSA:3.30.110.40 1 76 5.2E-28 T 14-10-2018 IPR036868 TusA-like domain superfamily Tharo_2521 de970698edf55d033b82134de5315ccd 76 SUPERFAMILY SSF64307 3 75 1.05E-22 T 14-10-2018 IPR036868 TusA-like domain superfamily Tharo_2521 de970698edf55d033b82134de5315ccd 76 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 7 31 - T 14-10-2018 IPR001455 TusA-like domain Tharo_1548 afa14692635c3f94499bfe039d033362 300 PRINTS PR00474 Glutamate 5-kinase family signature 199 226 1.6E-5 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Tharo_1548 afa14692635c3f94499bfe039d033362 300 PRINTS PR00474 Glutamate 5-kinase family signature 249 269 1.6E-5 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Tharo_1548 afa14692635c3f94499bfe039d033362 300 Pfam PF00696 Amino acid kinase family 32 276 9.0E-46 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Tharo_1548 afa14692635c3f94499bfe039d033362 300 PIRSF PIRSF000728 17 299 3.6E-106 T 14-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Tharo_1548 afa14692635c3f94499bfe039d033362 300 Hamap MF_00082 Acetylglutamate kinase [argB]. 31 292 51.359 T 14-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Tharo_1548 afa14692635c3f94499bfe039d033362 300 Gene3D G3DSA:3.40.1160.10 10 299 2.3E-99 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Tharo_1548 afa14692635c3f94499bfe039d033362 300 TIGRFAM TIGR00761 argB: acetylglutamate kinase 33 274 1.3E-75 T 14-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Tharo_1548 afa14692635c3f94499bfe039d033362 300 SUPERFAMILY SSF53633 12 299 1.44E-93 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Tharo_0359 ab8d35f416dc5b644327d309dd8ae35f 76 Gene3D G3DSA:3.40.1620.10 1 39 1.5E-10 T 14-10-2018 Tharo_0359 ab8d35f416dc5b644327d309dd8ae35f 76 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 40 9.0E-7 T 14-10-2018 Tharo_0359 ab8d35f416dc5b644327d309dd8ae35f 76 SUPERFAMILY SSF143120 1 40 7.06E-9 T 14-10-2018 IPR036165 YefM-like superfamily Tharo_0359 ab8d35f416dc5b644327d309dd8ae35f 76 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 40 1.9E-10 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Tharo_1797 d983c6c2f34bcf1cffeecfc2aa09407b 188 SUPERFAMILY SSF52266 1 176 1.53E-47 T 14-10-2018 Tharo_1797 d983c6c2f34bcf1cffeecfc2aa09407b 188 Gene3D G3DSA:3.40.50.1110 1 181 1.0E-67 T 14-10-2018 IPR036514 SGNH hydrolase superfamily Tharo_1797 d983c6c2f34bcf1cffeecfc2aa09407b 188 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 3 162 3.0E-27 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain Tharo_2532 b88ed479028ac2c4b9190d5d655fd682 259 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 143 216 3.6E-18 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Tharo_2532 b88ed479028ac2c4b9190d5d655fd682 259 SUPERFAMILY SSF58104 64 248 8.76E-25 T 14-10-2018 Tharo_2532 b88ed479028ac2c4b9190d5d655fd682 259 Gene3D G3DSA:1.10.287.950 45 259 2.6E-25 T 14-10-2018 Tharo_1112 6a895e6ee18d2ab3256aedd4144cc530 212 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 2 211 1.7E-85 T 14-10-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-204174|Reactome: R-HSA-71182 Tharo_1112 6a895e6ee18d2ab3256aedd4144cc530 212 Pfam PF13410 Glutathione S-transferase, C-terminal domain 134 177 2.3E-6 T 14-10-2018 Tharo_1112 6a895e6ee18d2ab3256aedd4144cc530 212 Gene3D G3DSA:3.40.30.10 1 87 2.6E-27 T 14-10-2018 Tharo_1112 6a895e6ee18d2ab3256aedd4144cc530 212 Gene3D G3DSA:1.20.1050.10 88 212 1.5E-50 T 14-10-2018 Tharo_1112 6a895e6ee18d2ab3256aedd4144cc530 212 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 80 1.7E-15 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 Tharo_1112 6a895e6ee18d2ab3256aedd4144cc530 212 SUPERFAMILY SSF47616 80 210 4.26E-30 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily Tharo_1112 6a895e6ee18d2ab3256aedd4144cc530 212 SUPERFAMILY SSF52833 1 84 2.5E-24 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_1780 3673e310a5b0d1deea3255fdb56e61b8 451 Gene3D G3DSA:3.90.1150.10 64 441 1.6E-138 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_1780 3673e310a5b0d1deea3255fdb56e61b8 451 Gene3D G3DSA:3.40.640.10 96 337 1.6E-138 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_1780 3673e310a5b0d1deea3255fdb56e61b8 451 Pfam PF00155 Aminotransferase class I and II 78 438 2.1E-46 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Tharo_1780 3673e310a5b0d1deea3255fdb56e61b8 451 SUPERFAMILY SSF53383 47 445 1.2E-96 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_2515 5b3ef597e7464dcc9974133044cf0bb1 358 Pfam PF03739 Predicted permease YjgP/YjgQ family 7 353 2.0E-75 T 14-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 Tharo_2515 5b3ef597e7464dcc9974133044cf0bb1 358 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 5 354 4.3E-124 T 14-10-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 Tharo_0292 bc224c29c5ddcbe5e9a560e1d221a6ba 198 SUPERFAMILY SSF81343 3 181 4.84E-6 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_3416 1ca3296757b187936a1ec6e284dd35fc 467 Gene3D G3DSA:2.40.128.260 278 456 4.0E-65 T 14-10-2018 Tharo_3416 1ca3296757b187936a1ec6e284dd35fc 467 Pfam PF03743 Bacterial conjugation TrbI-like protein 275 458 8.2E-61 T 14-10-2018 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI Tharo_3416 1ca3296757b187936a1ec6e284dd35fc 467 Gene3D G3DSA:1.10.1200.160 399 437 4.0E-65 T 14-10-2018 Tharo_2680 3b17154b5eb4c5cf87c683c0546ce74c 123 Gene3D G3DSA:1.10.260.40 53 121 8.3E-6 T 14-10-2018 Tharo_2680 3b17154b5eb4c5cf87c683c0546ce74c 123 SUPERFAMILY SSF47413 59 117 4.82E-5 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_2090 7057b028ae2b0b8979f7d034ddc54804 251 Gene3D G3DSA:2.160.10.10 67 189 8.7E-36 T 14-10-2018 Tharo_2090 7057b028ae2b0b8979f7d034ddc54804 251 Gene3D G3DSA:1.10.3130.10 1 66 2.7E-22 T 14-10-2018 Tharo_2090 7057b028ae2b0b8979f7d034ddc54804 251 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 71 107 6.4E-5 T 14-10-2018 IPR001451 Hexapeptide repeat Tharo_2090 7057b028ae2b0b8979f7d034ddc54804 251 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 118 151 6.6E-7 T 14-10-2018 IPR001451 Hexapeptide repeat Tharo_2090 7057b028ae2b0b8979f7d034ddc54804 251 SUPERFAMILY SSF51161 3 170 3.74E-57 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily Tharo_2090 7057b028ae2b0b8979f7d034ddc54804 251 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 6 167 6.2E-73 T 14-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 Tharo_2371 5a25f93093fede191f0e5a627ed53ee5 310 SUPERFAMILY SSF56524 62 306 3.01E-88 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 Tharo_2371 5a25f93093fede191f0e5a627ed53ee5 310 Hamap MF_01206 Protein-methionine-sulfoxide reductase catalytic subunit MsrP [msrP]. 7 310 54.377 T 14-10-2018 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 Tharo_2371 5a25f93093fede191f0e5a627ed53ee5 310 Pfam PF00174 Oxidoreductase molybdopterin binding domain 94 248 1.9E-29 T 14-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 Tharo_2371 5a25f93093fede191f0e5a627ed53ee5 310 Gene3D G3DSA:3.90.420.10 54 310 4.0E-103 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 Tharo_3049 9ca33a2c6d0533f445ddef095e004eeb 275 SUPERFAMILY SSF82861 19 103 3.27E-17 T 14-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 Tharo_3049 9ca33a2c6d0533f445ddef095e004eeb 275 Pfam PF00924 Mechanosensitive ion channel 63 259 2.3E-53 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 Tharo_3049 9ca33a2c6d0533f445ddef095e004eeb 275 Gene3D G3DSA:3.30.70.100 171 264 2.2E-29 T 14-10-2018 Tharo_3049 9ca33a2c6d0533f445ddef095e004eeb 275 SUPERFAMILY SSF82689 173 268 2.09E-32 T 14-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 Tharo_3049 9ca33a2c6d0533f445ddef095e004eeb 275 Gene3D G3DSA:2.30.30.60 120 169 8.4E-20 T 14-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily Tharo_3049 9ca33a2c6d0533f445ddef095e004eeb 275 SUPERFAMILY SSF50182 104 170 8.5E-18 T 14-10-2018 IPR010920 LSM domain superfamily Tharo_2610 218a75def42abe53d4e480b7d5c98913 740 Gene3D G3DSA:3.40.50.300 459 639 4.7E-25 T 14-10-2018 Tharo_2610 218a75def42abe53d4e480b7d5c98913 740 Pfam PF07728 AAA domain (dynein-related subfamily) 475 632 7.9E-29 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 Tharo_2610 218a75def42abe53d4e480b7d5c98913 740 SUPERFAMILY SSF52540 453 635 1.38E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2610 218a75def42abe53d4e480b7d5c98913 740 SMART SM00382 472 638 3.3E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_3215 25300ede180975a105781c7f26a71210 159 SUPERFAMILY SSF159664 6 139 2.49E-34 T 14-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 Tharo_3215 25300ede180975a105781c7f26a71210 159 Pfam PF01890 Cobalamin synthesis G C-terminus 8 136 1.1E-34 T 14-10-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 Tharo_3215 25300ede180975a105781c7f26a71210 159 Gene3D G3DSA:3.30.420.180 4 140 1.2E-39 T 14-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 Tharo_0371 f5dee1b18889c38b24449f274d8dc601 94 SUPERFAMILY SSF47413 22 79 3.75E-6 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_0371 f5dee1b18889c38b24449f274d8dc601 94 TIGRFAM TIGR02684 dnstrm_HI1420: probable addiction module antidote protein 6 81 2.6E-15 T 14-10-2018 IPR014057 Uncharacterized protein HI1420 Tharo_0371 f5dee1b18889c38b24449f274d8dc601 94 Gene3D G3DSA:1.10.260.40 25 81 2.1E-5 T 14-10-2018 Tharo_1747 ff73ff589720a556860edc1a3f728b4f 127 SUPERFAMILY SSF46626 6 116 2.56E-16 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_1747 ff73ff589720a556860edc1a3f728b4f 127 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 40 108 1.5E-9 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_1747 ff73ff589720a556860edc1a3f728b4f 127 Gene3D G3DSA:1.10.760.10 14 115 2.8E-12 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_0084 33d63a5d38670881c3574d0a3b6c0703 735 SUPERFAMILY SSF53474 200 322 5.06E-6 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_1825 7c3bfb4c78da5eab78f59e88856e768d 421 Gene3D G3DSA:3.40.50.2300 144 376 1.5E-82 T 14-10-2018 Tharo_1825 7c3bfb4c78da5eab78f59e88856e768d 421 Pfam PF13458 Periplasmic binding protein 25 376 3.7E-60 T 14-10-2018 IPR028081 Leucine-binding protein domain Tharo_1825 7c3bfb4c78da5eab78f59e88856e768d 421 Gene3D G3DSA:3.40.50.2300 48 368 1.5E-82 T 14-10-2018 Tharo_1825 7c3bfb4c78da5eab78f59e88856e768d 421 SUPERFAMILY SSF53822 25 382 1.07E-67 T 14-10-2018 IPR028082 Periplasmic binding protein-like I Tharo_1238 70c5b2a414bc6804af55e75109a037f5 292 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 38 55 - T 14-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Tharo_1238 70c5b2a414bc6804af55e75109a037f5 292 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 163 - T 14-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 Tharo_1238 70c5b2a414bc6804af55e75109a037f5 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 1.1E-35 T 14-10-2018 IPR002220 DapA-like GO:0016829 Tharo_1238 70c5b2a414bc6804af55e75109a037f5 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 1.1E-35 T 14-10-2018 IPR002220 DapA-like GO:0016829 Tharo_1238 70c5b2a414bc6804af55e75109a037f5 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 1.1E-35 T 14-10-2018 IPR002220 DapA-like GO:0016829 Tharo_1238 70c5b2a414bc6804af55e75109a037f5 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 1.1E-35 T 14-10-2018 IPR002220 DapA-like GO:0016829 Tharo_1238 70c5b2a414bc6804af55e75109a037f5 292 Pfam PF00701 Dihydrodipicolinate synthetase family 2 285 4.3E-99 T 14-10-2018 IPR002220 DapA-like GO:0016829 Tharo_1238 70c5b2a414bc6804af55e75109a037f5 292 SUPERFAMILY SSF51569 1 289 4.81E-104 T 14-10-2018 Tharo_1238 70c5b2a414bc6804af55e75109a037f5 292 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 5 286 1.9E-107 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Tharo_1238 70c5b2a414bc6804af55e75109a037f5 292 Gene3D G3DSA:3.20.20.70 2 292 1.2E-109 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_1238 70c5b2a414bc6804af55e75109a037f5 292 PIRSF PIRSF001365 1 292 2.5E-88 T 14-10-2018 IPR002220 DapA-like GO:0016829 Tharo_1238 70c5b2a414bc6804af55e75109a037f5 292 SMART SM01130 1 289 3.2E-142 T 14-10-2018 IPR002220 DapA-like GO:0016829 Tharo_1238 70c5b2a414bc6804af55e75109a037f5 292 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 287 66.37 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Tharo_0638 acd35a39b7135038537aa8bad8a72908 212 Gene3D G3DSA:3.40.50.880 1 211 2.7E-73 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Tharo_0638 acd35a39b7135038537aa8bad8a72908 212 PIRSF PIRSF000495 2 212 1.1E-67 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 Tharo_0638 acd35a39b7135038537aa8bad8a72908 212 Pfam PF00117 Glutamine amidotransferase class-I 6 207 1.7E-16 T 14-10-2018 IPR017926 Glutamine amidotransferase Tharo_0638 acd35a39b7135038537aa8bad8a72908 212 SUPERFAMILY SSF52317 2 210 2.72E-54 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Tharo_0638 acd35a39b7135038537aa8bad8a72908 212 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 210 36.059 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 Tharo_0638 acd35a39b7135038537aa8bad8a72908 212 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 210 9.0E-63 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 Tharo_2175 591d4b6090643ac6fdc0e05ae2264deb 298 SMART SM00471 101 238 0.003 T 14-10-2018 IPR003607 HD/PDEase domain Tharo_2175 591d4b6090643ac6fdc0e05ae2264deb 298 SUPERFAMILY SSF109604 92 267 5.14E-34 T 14-10-2018 Tharo_2175 591d4b6090643ac6fdc0e05ae2264deb 298 Gene3D G3DSA:1.10.3210.10 81 280 4.3E-59 T 14-10-2018 Tharo_2175 591d4b6090643ac6fdc0e05ae2264deb 298 Pfam PF01966 HD domain 107 227 4.4E-16 T 14-10-2018 IPR006674 HD domain Tharo_1067 36eb8dc214d343a6e5f0597e620e16af 260 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 10 221 1.4E-25 T 14-10-2018 Tharo_3322 54f4a79e15e403bc7ac83f1b358aa612 950 SUPERFAMILY SSF56935 263 948 1.79E-109 T 14-10-2018 Tharo_3322 54f4a79e15e403bc7ac83f1b358aa612 950 Pfam PF00593 TonB dependent receptor 473 946 4.1E-48 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Tharo_3322 54f4a79e15e403bc7ac83f1b358aa612 950 Pfam PF07715 TonB-dependent Receptor Plug Domain 289 397 6.1E-16 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain Tharo_3322 54f4a79e15e403bc7ac83f1b358aa612 950 Gene3D G3DSA:2.40.170.20 420 950 2.1E-84 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Tharo_3322 54f4a79e15e403bc7ac83f1b358aa612 950 Gene3D G3DSA:2.170.130.10 273 400 2.6E-18 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Tharo_1371 27641e4a8ccb239ca480a6b7c7d0da33 428 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 25 422 3.0E-179 T 14-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 Tharo_1371 27641e4a8ccb239ca480a6b7c7d0da33 428 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 234 253 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site Tharo_1371 27641e4a8ccb239ca480a6b7c7d0da33 428 Gene3D G3DSA:3.40.640.10 53 313 2.1E-174 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_1371 27641e4a8ccb239ca480a6b7c7d0da33 428 Gene3D G3DSA:3.90.1150.10 27 415 2.1E-174 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_1371 27641e4a8ccb239ca480a6b7c7d0da33 428 SUPERFAMILY SSF53383 27 418 4.27E-127 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_1371 27641e4a8ccb239ca480a6b7c7d0da33 428 Pfam PF00266 Aminotransferase class-V 42 411 6.1E-149 T 14-10-2018 IPR000192 Aminotransferase class V domain Tharo_1371 27641e4a8ccb239ca480a6b7c7d0da33 428 PIRSF PIRSF005572 39 419 2.6E-48 T 14-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 Tharo_1100 f98fe7a9829214fab8176bd3d32b439f 229 Gene3D G3DSA:3.50.30.100 2 199 4.6E-54 T 14-10-2018 Tharo_1100 f98fe7a9829214fab8176bd3d32b439f 229 Pfam PF03737 Aldolase/RraA 30 177 6.5E-41 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein Tharo_1100 f98fe7a9829214fab8176bd3d32b439f 229 SUPERFAMILY SSF89562 26 188 1.83E-48 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily Tharo_1100 f98fe7a9829214fab8176bd3d32b439f 229 TIGRFAM TIGR02798 ligK_PcmE: 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase 7 228 3.5E-120 T 14-10-2018 IPR014165 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase KEGG: 00362+4.1.3.17|KEGG: 00660+4.1.3.17|MetaCyc: PWY-7701 Tharo_3185 28ae6b4d52d9716fca894a45729399f9 107 Gene3D G3DSA:2.20.130.30 34 107 6.1E-28 T 14-10-2018 Tharo_3185 28ae6b4d52d9716fca894a45729399f9 107 Pfam PF11191 Protein of unknown function (DUF2782) 24 107 2.8E-32 T 14-10-2018 IPR021357 Protein of unknown function DUF2782 Tharo_1790 448dde2c796170823a2447e368a9bbec 120 SUPERFAMILY SSF52833 4 115 7.16E-29 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_1790 448dde2c796170823a2447e368a9bbec 120 Gene3D G3DSA:3.40.30.10 2 116 3.9E-38 T 14-10-2018 Tharo_1790 448dde2c796170823a2447e368a9bbec 120 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 6 111 8.0E-26 T 14-10-2018 IPR006504 Transcriptional regulator Spx/MgsR Tharo_1790 448dde2c796170823a2447e368a9bbec 120 Pfam PF03960 ArsC family 10 113 1.2E-14 T 14-10-2018 IPR006660 Arsenate reductase-like Tharo_2340 4dae69345b0195d86c18e51b8d58fcb2 451 Pfam PF02754 Cysteine-rich domain 336 412 2.8E-4 T 14-10-2018 IPR004017 Cysteine-rich domain Tharo_2340 4dae69345b0195d86c18e51b8d58fcb2 451 Pfam PF02754 Cysteine-rich domain 204 289 1.2E-5 T 14-10-2018 IPR004017 Cysteine-rich domain Tharo_2340 4dae69345b0195d86c18e51b8d58fcb2 451 SUPERFAMILY SSF54862 37 95 4.89E-5 T 14-10-2018 Tharo_3305 884353a624ad2a8c44f86d51f24e619b 414 Pfam PF07690 Major Facilitator Superfamily 26 265 2.9E-28 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_3305 884353a624ad2a8c44f86d51f24e619b 414 Gene3D G3DSA:1.20.1250.20 16 398 1.8E-50 T 14-10-2018 Tharo_3305 884353a624ad2a8c44f86d51f24e619b 414 SUPERFAMILY SSF103473 15 397 1.96E-62 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_0279 f0b1d3f8b55933e8fc78b7c90c6a99cf 123 Pfam PF12553 Protein of unknown function (DUF3742) 1 120 4.3E-43 T 14-10-2018 IPR022213 Protein of unknown function DUF3742 Tharo_0025 36f038d8fb7cc06ed3ce223eb549e04f 210 Pfam PF01810 LysE type translocator 16 205 2.3E-28 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 Tharo_0892 13107627630202335eed3c286ab32bfe 289 Gene3D G3DSA:3.40.1190.20 1 288 4.8E-94 T 14-10-2018 IPR029056 Ribokinase-like Tharo_0892 13107627630202335eed3c286ab32bfe 289 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 19 283 1.0E-85 T 14-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Tharo_0892 13107627630202335eed3c286ab32bfe 289 Pfam PF08543 Phosphomethylpyrimidine kinase 26 281 2.4E-83 T 14-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 Tharo_0892 13107627630202335eed3c286ab32bfe 289 SUPERFAMILY SSF53613 15 287 2.34E-71 T 14-10-2018 IPR029056 Ribokinase-like Tharo_2750 2208fa18f0b78adf58826d59acbed86e 327 Pfam PF00482 Type II secretion system (T2SS), protein F 160 284 2.1E-17 T 14-10-2018 IPR018076 Type II secretion system F domain Tharo_2750 2208fa18f0b78adf58826d59acbed86e 327 Gene3D G3DSA:1.20.81.30 153 262 1.4E-5 T 14-10-2018 Tharo_2328 bc96f874eeac854eed7440e17c9bd93e 284 Gene3D G3DSA:3.40.250.10 2 154 1.4E-42 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Tharo_2328 bc96f874eeac854eed7440e17c9bd93e 284 SUPERFAMILY SSF52821 4 155 1.06E-38 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Tharo_2328 bc96f874eeac854eed7440e17c9bd93e 284 SUPERFAMILY SSF52821 160 283 3.14E-33 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Tharo_2328 bc96f874eeac854eed7440e17c9bd93e 284 Gene3D G3DSA:3.40.250.10 162 282 2.5E-32 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Tharo_2328 bc96f874eeac854eed7440e17c9bd93e 284 Pfam PF00581 Rhodanese-like domain 11 130 3.9E-12 T 14-10-2018 IPR001763 Rhodanese-like domain Tharo_2328 bc96f874eeac854eed7440e17c9bd93e 284 Pfam PF00581 Rhodanese-like domain 160 272 1.4E-8 T 14-10-2018 IPR001763 Rhodanese-like domain Tharo_2328 bc96f874eeac854eed7440e17c9bd93e 284 SMART SM00450 157 277 8.4E-14 T 14-10-2018 IPR001763 Rhodanese-like domain Tharo_2328 bc96f874eeac854eed7440e17c9bd93e 284 SMART SM00450 9 135 9.2E-15 T 14-10-2018 IPR001763 Rhodanese-like domain Tharo_1999 fc6e86605ec316964253f023c3a0700e 226 SMART SM01018 11 94 3.8E-9 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_1999 fc6e86605ec316964253f023c3a0700e 226 Pfam PF02310 B12 binding domain 103 214 1.2E-21 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 Tharo_1999 fc6e86605ec316964253f023c3a0700e 226 Gene3D G3DSA:3.40.50.280 94 223 7.3E-41 T 14-10-2018 Tharo_1999 fc6e86605ec316964253f023c3a0700e 226 SUPERFAMILY SSF52242 90 223 8.77E-37 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 Tharo_1999 fc6e86605ec316964253f023c3a0700e 226 Gene3D G3DSA:1.10.1240.10 13 88 6.0E-20 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_1999 fc6e86605ec316964253f023c3a0700e 226 SUPERFAMILY SSF47644 14 90 2.22E-12 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_1999 fc6e86605ec316964253f023c3a0700e 226 Pfam PF02607 B12 binding domain 15 82 8.1E-11 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_1213 efdecede92b4dd2998cc814f09f0e035 111 Pfam PF06305 Lipopolysaccharide assembly protein A domain 26 87 2.7E-18 T 14-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 Tharo_0445 9cda5d4bab6d74639d078f7baf438004 478 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 158 166 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site Tharo_0445 9cda5d4bab6d74639d078f7baf438004 478 SMART SM00490 263 344 6.7E-31 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_0445 9cda5d4bab6d74639d078f7baf438004 478 SMART SM00487 24 227 1.2E-61 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Tharo_0445 9cda5d4bab6d74639d078f7baf438004 478 Gene3D G3DSA:3.40.50.300 2 215 7.1E-76 T 14-10-2018 Tharo_0445 9cda5d4bab6d74639d078f7baf438004 478 Pfam PF00270 DEAD/DEAH box helicase 29 200 1.0E-49 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Tharo_0445 9cda5d4bab6d74639d078f7baf438004 478 Gene3D G3DSA:3.40.50.300 219 396 3.6E-47 T 14-10-2018 Tharo_0445 9cda5d4bab6d74639d078f7baf438004 478 SUPERFAMILY SSF52540 27 106 6.37E-6 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0445 9cda5d4bab6d74639d078f7baf438004 478 Hamap MF_00968 ATP-dependent RNA helicase RhlE [rhlE]. 5 477 48.359 T 14-10-2018 IPR028622 ATP-dependent RNA helicase RhlE GO:0004004|GO:0042255 Tharo_0445 9cda5d4bab6d74639d078f7baf438004 478 SUPERFAMILY SSF52540 79 365 1.8E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0445 9cda5d4bab6d74639d078f7baf438004 478 Pfam PF00271 Helicase conserved C-terminal domain 239 344 3.3E-26 T 14-10-2018 IPR001650 Helicase, C-terminal Tharo_2177 1fe10a5ea2e8916c402bc5d48fe0cfb5 191 Pfam PF06930 Protein of unknown function (DUF1282) 13 178 4.0E-10 T 14-10-2018 IPR009698 Protein of unknown function DUF1282 Tharo_0695 187df2dd2be2ef17dc2303a4805f93e0 164 Gene3D G3DSA:3.40.140.10 41 164 8.9E-39 T 14-10-2018 Tharo_0695 187df2dd2be2ef17dc2303a4805f93e0 164 Pfam PF04002 RadC-like JAB domain 44 162 9.2E-39 T 14-10-2018 IPR025657 RadC-like JAB domain Tharo_0695 187df2dd2be2ef17dc2303a4805f93e0 164 SUPERFAMILY SSF102712 61 134 9.29E-5 T 14-10-2018 Tharo_0695 187df2dd2be2ef17dc2303a4805f93e0 164 TIGRFAM TIGR00608 radc: DNA repair protein RadC 27 164 1.0E-39 T 14-10-2018 IPR001405 Uncharacterised protein family UPF0758 Tharo_0583 384aac3e03b8912c2b17ed7d1acf0f63 691 SUPERFAMILY SSF52540 326 466 2.59E-5 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0583 384aac3e03b8912c2b17ed7d1acf0f63 691 Pfam PF06048 Domain of unknown function (DUF927) 141 418 9.9E-104 T 14-10-2018 IPR009270 Domain of unknown function DUF927 Tharo_2426 4d2d18028a54853ba84ad943f1ceaf8f 92 Pfam PF02583 Metal-sensitive transcriptional repressor 8 88 2.1E-21 T 14-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 Tharo_2426 4d2d18028a54853ba84ad943f1ceaf8f 92 Gene3D G3DSA:1.20.58.1000 1 92 4.9E-29 T 14-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily Tharo_0248 fb94eddfc3e1d77828984070386704eb 182 Pfam PF02417 Chromate transporter 11 177 3.9E-31 T 14-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 Tharo_2671 58cea3d2e26490bbba85691c1c6f4cb4 113 Gene3D G3DSA:2.160.10.10 3 112 3.0E-26 T 14-10-2018 Tharo_2671 58cea3d2e26490bbba85691c1c6f4cb4 113 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 51 75 2.1E-5 T 14-10-2018 IPR001451 Hexapeptide repeat Tharo_2671 58cea3d2e26490bbba85691c1c6f4cb4 113 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 14 49 6.8E-8 T 14-10-2018 IPR001451 Hexapeptide repeat Tharo_2671 58cea3d2e26490bbba85691c1c6f4cb4 113 SUPERFAMILY SSF51161 3 85 8.87E-24 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily Tharo_1878 ebd3fedfb3e81743eab22833fa240131 252 SUPERFAMILY SSF52096 2 252 8.87E-64 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_1878 ebd3fedfb3e81743eab22833fa240131 252 Gene3D G3DSA:3.90.226.10 1 252 1.1E-64 T 14-10-2018 Tharo_1878 ebd3fedfb3e81743eab22833fa240131 252 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 218 4.6E-41 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Tharo_2893 3371e6c3e3c1c36c05311fcd33611ae1 93 Gene3D G3DSA:1.10.260.40 16 93 1.7E-16 T 14-10-2018 Tharo_2893 3371e6c3e3c1c36c05311fcd33611ae1 93 SMART SM00530 33 88 2.0E-13 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_2893 3371e6c3e3c1c36c05311fcd33611ae1 93 Pfam PF01381 Helix-turn-helix 36 82 3.8E-14 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_2893 3371e6c3e3c1c36c05311fcd33611ae1 93 SUPERFAMILY SSF47413 23 90 3.66E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_1725 5e3102927026aaabb06970033c4d5bf0 420 Gene3D G3DSA:1.20.1250.20 2 185 1.1E-45 T 14-10-2018 Tharo_1725 5e3102927026aaabb06970033c4d5bf0 420 Pfam PF07690 Major Facilitator Superfamily 18 289 7.2E-35 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_1725 5e3102927026aaabb06970033c4d5bf0 420 SUPERFAMILY SSF103473 5 400 6.02E-65 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_1725 5e3102927026aaabb06970033c4d5bf0 420 Gene3D G3DSA:1.20.1250.20 191 408 2.2E-57 T 14-10-2018 Tharo_1330 108f0e8bd02439eeafe2cc0b5ae70faf 183 Pfam PF00877 NlpC/P60 family 73 177 3.9E-23 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain Tharo_1330 108f0e8bd02439eeafe2cc0b5ae70faf 183 SUPERFAMILY SSF54001 57 179 4.9E-33 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily Tharo_1330 108f0e8bd02439eeafe2cc0b5ae70faf 183 Gene3D G3DSA:3.90.1720.10 21 174 5.6E-34 T 14-10-2018 Tharo_2874 4c441c19a12f2400d7670a9288c3539f 152 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 25 141 3.1E-36 T 14-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 Tharo_2874 4c441c19a12f2400d7670a9288c3539f 152 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 22 145 1.3E-52 T 14-10-2018 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 Tharo_2874 4c441c19a12f2400d7670a9288c3539f 152 PIRSF PIRSF003230 12 152 1.3E-46 T 14-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 Tharo_2874 4c441c19a12f2400d7670a9288c3539f 152 Gene3D G3DSA:3.10.129.10 16 151 4.8E-44 T 14-10-2018 Tharo_2874 4c441c19a12f2400d7670a9288c3539f 152 Pfam PF03061 Thioesterase superfamily 36 120 2.5E-19 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 Tharo_2874 4c441c19a12f2400d7670a9288c3539f 152 SUPERFAMILY SSF54637 20 149 9.68E-43 T 14-10-2018 IPR029069 HotDog domain superfamily Tharo_2803 5b4d5cb20c43494bacd42f0597dbad64 1056 TIGRFAM TIGR03661 T1SS_VCA0849: type I secretion C-terminal target domain (VC_A0849 subclass) 964 1055 8.1E-13 T 14-10-2018 IPR019960 Type I secretion C-terminal target domain, VC_A0849 subclass Tharo_2803 5b4d5cb20c43494bacd42f0597dbad64 1056 SUPERFAMILY SSF141072 288 382 6.41E-7 T 14-10-2018 IPR038081 CalX-like domain superfamily Tharo_2670 6be54f1cb19a3285eb0ae91ebe27607b 158 Gene3D G3DSA:3.40.50.720 105 128 2.6E-36 T 14-10-2018 Tharo_2670 6be54f1cb19a3285eb0ae91ebe27607b 158 Gene3D G3DSA:3.30.360.10 2 150 2.6E-36 T 14-10-2018 Tharo_2670 6be54f1cb19a3285eb0ae91ebe27607b 158 SUPERFAMILY SSF55347 3 96 5.07E-15 T 14-10-2018 Tharo_1713 6e79be5cc2ce50f3cf24ebcfaa84b51b 122 SUPERFAMILY SSF52172 2 121 2.42E-39 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1713 6e79be5cc2ce50f3cf24ebcfaa84b51b 122 Pfam PF00072 Response regulator receiver domain 5 116 5.2E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1713 6e79be5cc2ce50f3cf24ebcfaa84b51b 122 Gene3D G3DSA:3.40.50.12740 1 122 1.8E-45 T 14-10-2018 Tharo_1713 6e79be5cc2ce50f3cf24ebcfaa84b51b 122 SMART SM00448 3 116 1.2E-40 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_0305 9b1edd1e67cd08fed660ded7e11ee82f 301 TIGRFAM TIGR03749 conj_TIGR03749: integrating conjugative element protein, PFL_4704 family 14 272 5.3E-111 T 14-10-2018 IPR021844 Integrating conjugative element protein, PFL4704 Tharo_0305 9b1edd1e67cd08fed660ded7e11ee82f 301 Pfam PF11920 Protein of unknown function (DUF3438) 12 281 9.5E-123 T 14-10-2018 IPR021844 Integrating conjugative element protein, PFL4704 Tharo_0355 64edd83ee4010282a2f675384e6432cf 107 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 92 105 2.3E-14 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 Tharo_0355 64edd83ee4010282a2f675384e6432cf 107 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 71 87 2.3E-14 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 Tharo_0355 64edd83ee4010282a2f675384e6432cf 107 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 36 52 2.3E-14 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 Tharo_0355 64edd83ee4010282a2f675384e6432cf 107 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 3 107 17.335 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 Tharo_0355 64edd83ee4010282a2f675384e6432cf 107 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 25 107 1.6E-22 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 Tharo_0355 64edd83ee4010282a2f675384e6432cf 107 Pfam PF02049 Flagellar hook-basal body complex protein FliE 22 107 4.8E-28 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 Tharo_0923 15854a655b340df8485624d8c340c429 411 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 42 401 1.1E-128 T 14-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_0923 15854a655b340df8485624d8c340c429 411 Pfam PF01098 Cell cycle protein 44 403 2.6E-105 T 14-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_0923 15854a655b340df8485624d8c340c429 411 Hamap MF_00913 Probable peptidoglycan glycosyltransferase FtsW [ftsW]. 39 410 41.39 T 14-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_1757 f0b9bd7ad650c991b9b0df7242ed1659 338 SUPERFAMILY SSF54862 110 304 7.78E-5 T 14-10-2018 Tharo_1757 f0b9bd7ad650c991b9b0df7242ed1659 338 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 294 305 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_1757 f0b9bd7ad650c991b9b0df7242ed1659 338 Pfam PF12801 4Fe-4S binding domain 210 244 0.013 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_1757 f0b9bd7ad650c991b9b0df7242ed1659 338 Pfam PF12801 4Fe-4S binding domain 98 141 3.1E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_0622 a2d31a43f9af319d29a45b0aa3879d4f 545 Gene3D G3DSA:3.55.50.30 60 145 9.4E-6 T 14-10-2018 Tharo_0622 a2d31a43f9af319d29a45b0aa3879d4f 545 PRINTS PR00811 Bacterial general secretion pathway protein D signature 266 276 2.5E-15 T 14-10-2018 IPR001775 GspD/PilQ family Tharo_0622 a2d31a43f9af319d29a45b0aa3879d4f 545 PRINTS PR00811 Bacterial general secretion pathway protein D signature 492 506 2.5E-15 T 14-10-2018 IPR001775 GspD/PilQ family Tharo_0622 a2d31a43f9af319d29a45b0aa3879d4f 545 PRINTS PR00811 Bacterial general secretion pathway protein D signature 322 346 2.5E-15 T 14-10-2018 IPR001775 GspD/PilQ family Tharo_0622 a2d31a43f9af319d29a45b0aa3879d4f 545 PRINTS PR00811 Bacterial general secretion pathway protein D signature 469 487 2.5E-15 T 14-10-2018 IPR001775 GspD/PilQ family Tharo_0622 a2d31a43f9af319d29a45b0aa3879d4f 545 Pfam PF00263 Bacterial type II and III secretion system protein 327 504 2.5E-38 T 14-10-2018 IPR004846 Type II/III secretion system GO:0009306 Tharo_1704 71dc396d6fa321cee75b5db12177dea1 136 Pfam PF01641 SelR domain 11 129 6.8E-53 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 Tharo_1704 71dc396d6fa321cee75b5db12177dea1 136 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 8 131 34.988 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 Tharo_1704 71dc396d6fa321cee75b5db12177dea1 136 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 7 129 4.1E-55 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 Tharo_1704 71dc396d6fa321cee75b5db12177dea1 136 SUPERFAMILY SSF51316 6 132 8.37E-59 T 14-10-2018 IPR011057 Mss4-like superfamily Tharo_1704 71dc396d6fa321cee75b5db12177dea1 136 Gene3D G3DSA:2.170.150.20 1 133 5.6E-61 T 14-10-2018 Tharo_1372 0ffc34bbabb91ff134248941518eab5b 440 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 149 419 2.1E-81 T 14-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 Tharo_1372 0ffc34bbabb91ff134248941518eab5b 440 Pfam PF01458 Uncharacterized protein family (UPF0051) 181 405 2.5E-74 T 14-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 Tharo_1372 0ffc34bbabb91ff134248941518eab5b 440 SUPERFAMILY SSF101960 24 430 8.11E-100 T 14-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily Tharo_2945 da8a861f6ebf049de6d104f45c87f37a 261 SUPERFAMILY SSF52096 1 258 5.71E-73 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_2945 da8a861f6ebf049de6d104f45c87f37a 261 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 102 122 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 Tharo_2945 da8a861f6ebf049de6d104f45c87f37a 261 Gene3D G3DSA:3.90.226.10 1 201 1.5E-60 T 14-10-2018 Tharo_2945 da8a861f6ebf049de6d104f45c87f37a 261 Gene3D G3DSA:1.10.12.10 203 261 8.1E-18 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal Tharo_2945 da8a861f6ebf049de6d104f45c87f37a 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 258 1.5E-52 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Tharo_0817 29a77b6673aa47b945c089e353bddf4b 504 Gene3D G3DSA:3.50.80.20 101 193 3.5E-17 T 14-10-2018 Tharo_0817 29a77b6673aa47b945c089e353bddf4b 504 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 396 410 2.2E-18 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Tharo_0817 29a77b6673aa47b945c089e353bddf4b 504 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 381 395 2.2E-18 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Tharo_0817 29a77b6673aa47b945c089e353bddf4b 504 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 77 96 2.2E-18 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Tharo_0817 29a77b6673aa47b945c089e353bddf4b 504 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 458 471 2.2E-18 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Tharo_0817 29a77b6673aa47b945c089e353bddf4b 504 SUPERFAMILY SSF56601 36 501 4.83E-86 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Tharo_0817 29a77b6673aa47b945c089e353bddf4b 504 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 52 342 1.7E-45 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Tharo_0817 29a77b6673aa47b945c089e353bddf4b 504 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 365 497 3.4E-29 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Tharo_0817 29a77b6673aa47b945c089e353bddf4b 504 Gene3D G3DSA:3.40.710.10 291 499 3.1E-53 T 14-10-2018 Tharo_1617 c4042b17cc5098e87c12682348c2af89 223 Pfam PF14622 Ribonuclease-III-like 17 136 4.5E-32 T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 Tharo_1617 c4042b17cc5098e87c12682348c2af89 223 SUPERFAMILY SSF69065 4 154 1.05E-43 T 14-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 Tharo_1617 c4042b17cc5098e87c12682348c2af89 223 Hamap MF_00104 Ribonuclease 3 [rnc]. 6 217 27.393 T 14-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 Tharo_1617 c4042b17cc5098e87c12682348c2af89 223 Gene3D G3DSA:1.10.1520.10 1 144 1.8E-39 T 14-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 Tharo_1617 c4042b17cc5098e87c12682348c2af89 223 SMART SM00535 18 146 2.9E-46 T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 Tharo_1617 c4042b17cc5098e87c12682348c2af89 223 ProSitePatterns PS00517 Ribonuclease III family signature. 35 43 - T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 Tharo_1617 c4042b17cc5098e87c12682348c2af89 223 SUPERFAMILY SSF54768 106 220 1.18E-22 T 14-10-2018 Tharo_1617 c4042b17cc5098e87c12682348c2af89 223 Gene3D G3DSA:3.30.160.20 151 222 9.7E-16 T 14-10-2018 Tharo_1617 c4042b17cc5098e87c12682348c2af89 223 SMART SM00358 153 221 1.2E-13 T 14-10-2018 IPR014720 Double-stranded RNA-binding domain Tharo_1617 c4042b17cc5098e87c12682348c2af89 223 Pfam PF00035 Double-stranded RNA binding motif 153 217 8.1E-8 T 14-10-2018 IPR014720 Double-stranded RNA-binding domain Tharo_1617 c4042b17cc5098e87c12682348c2af89 223 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 6 218 5.7E-63 T 14-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 Tharo_1963 1c59d6ccdb1546f7df15d34abdacc1b4 212 SUPERFAMILY SSF159594 40 199 1.18E-30 T 14-10-2018 Tharo_1963 1c59d6ccdb1546f7df15d34abdacc1b4 212 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 62 191 5.5E-9 T 14-10-2018 IPR005586 ABC-type transport auxiliary lipoprotein component Tharo_1963 1c59d6ccdb1546f7df15d34abdacc1b4 212 Gene3D G3DSA:3.40.50.10610 35 201 8.5E-22 T 14-10-2018 Tharo_0045 900d43a1b8ac2826f63f84d8e9522be2 248 Gene3D G3DSA:3.30.70.580 71 236 8.8E-46 T 14-10-2018 Tharo_0045 900d43a1b8ac2826f63f84d8e9522be2 248 SUPERFAMILY SSF55174 4 100 9.27E-8 T 14-10-2018 Tharo_0045 900d43a1b8ac2826f63f84d8e9522be2 248 Gene3D G3DSA:3.10.290.10 2 64 1.3E-7 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Tharo_0045 900d43a1b8ac2826f63f84d8e9522be2 248 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 109 123 - T 14-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 Tharo_0045 900d43a1b8ac2826f63f84d8e9522be2 248 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 75 233 1.3E-36 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 Tharo_0045 900d43a1b8ac2826f63f84d8e9522be2 248 Pfam PF00849 RNA pseudouridylate synthase 71 200 1.1E-11 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_0045 900d43a1b8ac2826f63f84d8e9522be2 248 SUPERFAMILY SSF55120 70 236 2.7E-36 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Tharo_0045 900d43a1b8ac2826f63f84d8e9522be2 248 Gene3D G3DSA:3.30.70.1560 138 219 8.8E-46 T 14-10-2018 Tharo_2030 f3a5b5ffcc24b99f5b3dab4698413ece 298 SUPERFAMILY SSF48576 8 294 1.35E-70 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily Tharo_2030 f3a5b5ffcc24b99f5b3dab4698413ece 298 Gene3D G3DSA:1.10.600.10 4 273 5.8E-80 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily Tharo_2030 f3a5b5ffcc24b99f5b3dab4698413ece 298 Pfam PF00494 Squalene/phytoene synthase 9 281 9.9E-65 T 14-10-2018 Tharo_2030 f3a5b5ffcc24b99f5b3dab4698413ece 298 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 6 292 8.0E-106 T 14-10-2018 IPR017827 Hydroxysqualene synthase HpnC MetaCyc: PWY-7072 Tharo_1932 0d80325550290affc3f562e3d54ff380 316 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 135 155 - T 14-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 Tharo_1932 0d80325550290affc3f562e3d54ff380 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 198 214 2.6E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_1932 0d80325550290affc3f562e3d54ff380 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 40 55 2.6E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_1932 0d80325550290affc3f562e3d54ff380 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 140 2.6E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_1932 0d80325550290affc3f562e3d54ff380 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 167 2.6E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_1932 0d80325550290affc3f562e3d54ff380 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 106 114 2.6E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_1932 0d80325550290affc3f562e3d54ff380 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 275 293 2.6E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_1932 0d80325550290affc3f562e3d54ff380 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 237 258 2.6E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_1932 0d80325550290affc3f562e3d54ff380 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 2.6E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_1932 0d80325550290affc3f562e3d54ff380 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 2.6E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Tharo_1932 0d80325550290affc3f562e3d54ff380 316 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 7 312 4.8E-120 T 14-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 Tharo_1932 0d80325550290affc3f562e3d54ff380 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 2.3E-39 T 14-10-2018 Tharo_1932 0d80325550290affc3f562e3d54ff380 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 2.3E-39 T 14-10-2018 Tharo_1932 0d80325550290affc3f562e3d54ff380 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 2.3E-39 T 14-10-2018 Tharo_1932 0d80325550290affc3f562e3d54ff380 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 2.3E-39 T 14-10-2018 Tharo_1932 0d80325550290affc3f562e3d54ff380 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.3E-39 T 14-10-2018 Tharo_1932 0d80325550290affc3f562e3d54ff380 316 SUPERFAMILY SSF51905 1 312 1.3E-50 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1932 0d80325550290affc3f562e3d54ff380 316 Gene3D G3DSA:3.50.50.60 117 243 3.3E-122 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1932 0d80325550290affc3f562e3d54ff380 316 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 300 3.4E-46 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Tharo_1932 0d80325550290affc3f562e3d54ff380 316 Gene3D G3DSA:3.50.50.60 9 311 3.3E-122 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_0043 be426f5aae836e5b882b9302d11ff7db 322 Pfam PF04381 Putative exonuclease, RdgC 1 297 3.4E-127 T 14-10-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 Tharo_0043 be426f5aae836e5b882b9302d11ff7db 322 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 1 299 38.502 T 14-10-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 Tharo_0334 91bbb39d5d26a9147c7c872910c858a3 252 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 121 3.3E-35 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G Tharo_0334 91bbb39d5d26a9147c7c872910c858a3 252 Pfam PF00460 Flagella basal body rod protein 5 35 5.1E-9 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 Tharo_0334 91bbb39d5d26a9147c7c872910c858a3 252 SUPERFAMILY SSF117143 79 209 3.79E-15 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like Tharo_0334 91bbb39d5d26a9147c7c872910c858a3 252 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 170 247 3.6E-23 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain Tharo_1065 1655a2fabedb7d1ce6f0fc0669d848fa 276 Pfam PF01578 Cytochrome C assembly protein 49 270 2.1E-29 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 Tharo_3268 bdc0a2a412765e7647b2740020296d95 643 Gene3D G3DSA:3.40.50.720 141 264 7.1E-32 T 14-10-2018 Tharo_3268 bdc0a2a412765e7647b2740020296d95 643 Gene3D G3DSA:3.40.50.720 278 580 5.3E-112 T 14-10-2018 Tharo_3268 bdc0a2a412765e7647b2740020296d95 643 Pfam PF13727 CoA-binding domain 61 234 2.8E-11 T 14-10-2018 Tharo_3268 bdc0a2a412765e7647b2740020296d95 643 Pfam PF02719 Polysaccharide biosynthesis protein 284 567 3.8E-116 T 14-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain Tharo_3268 bdc0a2a412765e7647b2740020296d95 643 SUPERFAMILY SSF51735 143 270 3.94E-21 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_3268 bdc0a2a412765e7647b2740020296d95 643 SUPERFAMILY SSF51735 277 546 8.24E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_3043 930ef18fe1e8ca9dbb61ac75f1e8157e 106 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 7 44 8.1E-11 T 14-10-2018 Tharo_3043 930ef18fe1e8ca9dbb61ac75f1e8157e 106 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 3 50 1.2E-11 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Tharo_3043 930ef18fe1e8ca9dbb61ac75f1e8157e 106 SUPERFAMILY SSF143120 3 48 3.79E-11 T 14-10-2018 IPR036165 YefM-like superfamily Tharo_3043 930ef18fe1e8ca9dbb61ac75f1e8157e 106 Gene3D G3DSA:3.40.1620.10 1 40 1.2E-7 T 14-10-2018 Tharo_1681 3ffa6b90c3d3b2cc855963d619ebe5f1 279 SUPERFAMILY SSF159713 41 263 5.89E-41 T 14-10-2018 Tharo_1681 3ffa6b90c3d3b2cc855963d619ebe5f1 279 Gene3D G3DSA:3.40.50.11590 133 247 1.3E-23 T 14-10-2018 Tharo_1681 3ffa6b90c3d3b2cc855963d619ebe5f1 279 Pfam PF04016 Putative heavy-metal chelation 137 266 1.7E-30 T 14-10-2018 IPR007161 Putative heavy-metal chelation domain Tharo_0010 da8b54604597837ddd259e5d36a7f10a 80 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 53 6.9E-8 T 14-10-2018 Tharo_0010 da8b54604597837ddd259e5d36a7f10a 80 Gene3D G3DSA:3.40.1620.40 2 67 3.7E-23 T 14-10-2018 Tharo_0010 da8b54604597837ddd259e5d36a7f10a 80 SUPERFAMILY SSF143120 1 79 1.28E-20 T 14-10-2018 IPR036165 YefM-like superfamily Tharo_0010 da8b54604597837ddd259e5d36a7f10a 80 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 69 9.0E-19 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Tharo_3085 81de852159356c1878198048932a114f 397 SUPERFAMILY SSF89796 2 395 4.19E-107 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily Tharo_3085 81de852159356c1878198048932a114f 397 Gene3D G3DSA:3.40.50.10540 2 390 9.4E-119 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily Tharo_3085 81de852159356c1878198048932a114f 397 Gene3D G3DSA:3.30.1540.10 230 323 9.4E-119 T 14-10-2018 Tharo_3085 81de852159356c1878198048932a114f 397 Pfam PF02515 CoA-transferase family III 2 372 2.8E-112 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 Tharo_1651 8969ed2977328d784e0cd0301b3dc846 116 Pfam PF02627 Carboxymuconolactone decarboxylase family 24 106 9.7E-20 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Tharo_1651 8969ed2977328d784e0cd0301b3dc846 116 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 41 87 4.4E-14 T 14-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Tharo_1651 8969ed2977328d784e0cd0301b3dc846 116 SUPERFAMILY SSF69118 5 110 1.22E-28 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 Tharo_1651 8969ed2977328d784e0cd0301b3dc846 116 Gene3D G3DSA:1.20.1290.10 1 112 1.0E-34 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 Tharo_1435 aeb2d6bf962e5afc231c84eedb6aa8f6 228 Gene3D G3DSA:1.10.4070.10 75 156 6.4E-11 T 14-10-2018 Tharo_1435 aeb2d6bf962e5afc231c84eedb6aa8f6 228 Pfam PF02613 Nitrate reductase delta subunit 39 137 1.1E-9 T 14-10-2018 IPR020945 DMSO/Nitrate reductase chaperone Tharo_1435 aeb2d6bf962e5afc231c84eedb6aa8f6 228 SUPERFAMILY SSF89155 10 169 1.44E-29 T 14-10-2018 IPR036411 TorD-like superfamily Tharo_1435 aeb2d6bf962e5afc231c84eedb6aa8f6 228 Gene3D G3DSA:1.20.120.700 16 164 6.4E-11 T 14-10-2018 Tharo_1435 aeb2d6bf962e5afc231c84eedb6aa8f6 228 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 15 167 5.7E-34 T 14-10-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 Tharo_2840 919ae469a9f5ecb04f421a81648f4dce 176 Gene3D G3DSA:1.10.10.10 37 119 4.7E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2840 919ae469a9f5ecb04f421a81648f4dce 176 SUPERFAMILY SSF46785 42 164 2.94E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_2840 919ae469a9f5ecb04f421a81648f4dce 176 Pfam PF01475 Ferric uptake regulator family 49 162 3.2E-20 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 Tharo_2814 22f242afcb29e7cb171b6cde08ec6e7e 331 PRINTS PR00691 Adhesin B signature 263 280 1.6E-20 T 14-10-2018 IPR006129 Adhesin B GO:0007155 Tharo_2814 22f242afcb29e7cb171b6cde08ec6e7e 331 PRINTS PR00691 Adhesin B signature 214 231 1.6E-20 T 14-10-2018 IPR006129 Adhesin B GO:0007155 Tharo_2814 22f242afcb29e7cb171b6cde08ec6e7e 331 PRINTS PR00691 Adhesin B signature 306 324 1.6E-20 T 14-10-2018 IPR006129 Adhesin B GO:0007155 Tharo_2814 22f242afcb29e7cb171b6cde08ec6e7e 331 PRINTS PR00691 Adhesin B signature 44 65 1.6E-20 T 14-10-2018 IPR006129 Adhesin B GO:0007155 Tharo_2814 22f242afcb29e7cb171b6cde08ec6e7e 331 PRINTS PR00691 Adhesin B signature 285 303 1.6E-20 T 14-10-2018 IPR006129 Adhesin B GO:0007155 Tharo_2814 22f242afcb29e7cb171b6cde08ec6e7e 331 PRINTS PR00691 Adhesin B signature 69 87 1.6E-20 T 14-10-2018 IPR006129 Adhesin B GO:0007155 Tharo_2814 22f242afcb29e7cb171b6cde08ec6e7e 331 PRINTS PR00691 Adhesin B signature 88 107 1.6E-20 T 14-10-2018 IPR006129 Adhesin B GO:0007155 Tharo_2814 22f242afcb29e7cb171b6cde08ec6e7e 331 Gene3D G3DSA:3.40.50.1980 203 329 3.6E-43 T 14-10-2018 Tharo_2814 22f242afcb29e7cb171b6cde08ec6e7e 331 Gene3D G3DSA:3.40.50.1980 45 200 1.7E-47 T 14-10-2018 Tharo_2814 22f242afcb29e7cb171b6cde08ec6e7e 331 Pfam PF01297 Zinc-uptake complex component A periplasmic 47 326 3.5E-77 T 14-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 Tharo_2814 22f242afcb29e7cb171b6cde08ec6e7e 331 PRINTS PR00690 Adhesin family signature 293 312 9.4E-26 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 Tharo_2814 22f242afcb29e7cb171b6cde08ec6e7e 331 PRINTS PR00690 Adhesin family signature 88 105 9.4E-26 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 Tharo_2814 22f242afcb29e7cb171b6cde08ec6e7e 331 PRINTS PR00690 Adhesin family signature 214 235 9.4E-26 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 Tharo_2814 22f242afcb29e7cb171b6cde08ec6e7e 331 PRINTS PR00690 Adhesin family signature 44 62 9.4E-26 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 Tharo_2814 22f242afcb29e7cb171b6cde08ec6e7e 331 PRINTS PR00690 Adhesin family signature 75 88 9.4E-26 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 Tharo_2814 22f242afcb29e7cb171b6cde08ec6e7e 331 PRINTS PR00690 Adhesin family signature 267 285 9.4E-26 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 Tharo_2814 22f242afcb29e7cb171b6cde08ec6e7e 331 SUPERFAMILY SSF53807 40 327 1.47E-81 T 14-10-2018 Tharo_3006 cd15c6e5cd57911a15526f5f1842175e 345 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 33 317 7.0E-53 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 Tharo_3006 cd15c6e5cd57911a15526f5f1842175e 345 Gene3D G3DSA:3.40.190.170 27 345 1.5E-111 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily Tharo_3228 835713d3b7ccb958b1d4b8e15bc53759 86 SUPERFAMILY SSF47598 6 50 2.67E-6 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Tharo_3228 835713d3b7ccb958b1d4b8e15bc53759 86 Gene3D G3DSA:1.10.8.1250 16 85 1.4E-5 T 14-10-2018 IPR038296 Antitoxin ParD superfamily Tharo_2880 6ef06c76a0204c7a4ebb6639f4a16f3b 237 SUPERFAMILY SSF48452 118 233 3.35E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_2880 6ef06c76a0204c7a4ebb6639f4a16f3b 237 Pfam PF16331 TolA binding protein trimerisation 44 107 1.4E-18 T 14-10-2018 IPR032519 YbgF, trimerisation domain GO:0070206 Tharo_2880 6ef06c76a0204c7a4ebb6639f4a16f3b 237 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 117 234 7.3E-37 T 14-10-2018 IPR014162 Cell division coordinator CpoB, C-terminal Tharo_2880 6ef06c76a0204c7a4ebb6639f4a16f3b 237 Pfam PF13525 Outer membrane lipoprotein 118 235 6.4E-10 T 14-10-2018 IPR039565 Outer membrane lipoprotein BamD-like Tharo_2880 6ef06c76a0204c7a4ebb6639f4a16f3b 237 Gene3D G3DSA:1.25.40.10 117 237 3.6E-26 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_2880 6ef06c76a0204c7a4ebb6639f4a16f3b 237 Hamap MF_02066 Cell division coordinator CpoB [cpoB]. 1 237 18.668 T 14-10-2018 IPR034706 Cell division coordinator CpoB GO:0051301 Tharo_2794 dd860a93ba6fb2c22ce64e1ebe1c8e6c 327 Pfam PF03308 ArgK protein 23 293 5.3E-108 T 14-10-2018 Tharo_2794 dd860a93ba6fb2c22ce64e1ebe1c8e6c 327 Gene3D G3DSA:1.20.5.170 2 51 1.3E-11 T 14-10-2018 Tharo_2794 dd860a93ba6fb2c22ce64e1ebe1c8e6c 327 Gene3D G3DSA:1.10.287.130 263 324 6.7E-21 T 14-10-2018 Tharo_2794 dd860a93ba6fb2c22ce64e1ebe1c8e6c 327 SUPERFAMILY SSF52540 10 322 4.29E-94 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2794 dd860a93ba6fb2c22ce64e1ebe1c8e6c 327 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 20 318 1.2E-102 T 14-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Tharo_2794 dd860a93ba6fb2c22ce64e1ebe1c8e6c 327 Gene3D G3DSA:3.40.50.300 52 261 6.9E-82 T 14-10-2018 Tharo_0624 4bf5f42450d19c62a90e671101fd8d5c 263 Pfam PF02405 Permease MlaE 47 257 3.9E-73 T 14-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 Tharo_0624 4bf5f42450d19c62a90e671101fd8d5c 263 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 33 262 9.5E-84 T 14-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria Tharo_2528 aa1ebdb7f3ee9c1af4c96e2a9e775ba4 238 Gene3D G3DSA:1.10.3720.10 1 235 5.3E-27 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_2528 aa1ebdb7f3ee9c1af4c96e2a9e775ba4 238 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 48 235 2.7E-10 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Tharo_2528 aa1ebdb7f3ee9c1af4c96e2a9e775ba4 238 SUPERFAMILY SSF161098 22 226 1.28E-30 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_3029 a648b7bbb76ce9db617c9de48fe2136f 126 Pfam PF09345 Domain of unknown function (DUF1987) 6 122 2.9E-40 T 14-10-2018 IPR018530 Domain of unknown function DUF1987 Tharo_0868 a9e0a905424e05e4fae690904fd8b1b1 953 Pfam PF13244 Domain of unknown function (DUF4040) 609 673 1.9E-18 T 14-10-2018 IPR025383 Domain of unknown function DUF4040 Tharo_0868 a9e0a905424e05e4fae690904fd8b1b1 953 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 794 917 1.9E-34 T 14-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein Tharo_0868 a9e0a905424e05e4fae690904fd8b1b1 953 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 60 113 1.0E-8 T 14-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_0868 a9e0a905424e05e4fae690904fd8b1b1 953 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 2.7E-34 T 14-10-2018 Tharo_0868 a9e0a905424e05e4fae690904fd8b1b1 953 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 306 318 2.7E-34 T 14-10-2018 Tharo_0868 a9e0a905424e05e4fae690904fd8b1b1 953 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 103 123 2.7E-34 T 14-10-2018 Tharo_0868 a9e0a905424e05e4fae690904fd8b1b1 953 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 414 433 2.7E-34 T 14-10-2018 Tharo_0868 a9e0a905424e05e4fae690904fd8b1b1 953 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 75 100 2.7E-34 T 14-10-2018 Tharo_0868 a9e0a905424e05e4fae690904fd8b1b1 953 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 238 264 2.7E-34 T 14-10-2018 Tharo_0868 a9e0a905424e05e4fae690904fd8b1b1 953 Pfam PF00361 Proton-conducting membrane transporter 126 404 8.1E-65 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1418 d1a4b49a936805f0224eb0f8644698a1 193 Pfam PF00892 EamA-like transporter family 40 172 9.7E-13 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Tharo_1418 d1a4b49a936805f0224eb0f8644698a1 193 SUPERFAMILY SSF103481 45 177 1.44E-7 T 14-10-2018 Tharo_2941 a75eea4d70d9969260ef879fca105c47 383 SUPERFAMILY SSF56645 7 244 5.24E-71 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Tharo_2941 a75eea4d70d9969260ef879fca105c47 383 Gene3D G3DSA:1.20.140.10 239 383 4.8E-40 T 14-10-2018 Tharo_2941 a75eea4d70d9969260ef879fca105c47 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 221 2.2E-27 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Tharo_2941 a75eea4d70d9969260ef879fca105c47 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 382 6.7E-38 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Tharo_2941 a75eea4d70d9969260ef879fca105c47 383 SUPERFAMILY SSF47203 232 383 2.42E-43 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Tharo_2941 a75eea4d70d9969260ef879fca105c47 383 Gene3D G3DSA:1.10.540.10 5 124 3.0E-29 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Tharo_2941 a75eea4d70d9969260ef879fca105c47 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 121 3.2E-26 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Tharo_2941 a75eea4d70d9969260ef879fca105c47 383 Gene3D G3DSA:2.40.110.10 126 238 1.1E-38 T 14-10-2018 Tharo_2941 a75eea4d70d9969260ef879fca105c47 383 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 128 140 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Tharo_2922 7e57024f9d36774a2db69453c5705485 511 Gene3D G3DSA:3.40.462.10 228 464 7.9E-60 T 14-10-2018 IPR016170 Cytokinin dehydrogenase, C-terminal domain superfamily KEGG: 00908+1.5.99.12 Tharo_2922 7e57024f9d36774a2db69453c5705485 511 Gene3D G3DSA:3.30.465.10 100 227 6.4E-54 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Tharo_2922 7e57024f9d36774a2db69453c5705485 511 Gene3D G3DSA:3.30.43.10 2 99 5.6E-25 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 Tharo_2922 7e57024f9d36774a2db69453c5705485 511 Pfam PF02913 FAD linked oxidases, C-terminal domain 331 502 1.0E-9 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 Tharo_2922 7e57024f9d36774a2db69453c5705485 511 SUPERFAMILY SSF55103 232 505 5.23E-38 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 Tharo_2922 7e57024f9d36774a2db69453c5705485 511 SUPERFAMILY SSF56176 4 227 1.56E-54 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Tharo_2922 7e57024f9d36774a2db69453c5705485 511 Gene3D G3DSA:1.10.45.10 477 511 3.7E-8 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 Tharo_2922 7e57024f9d36774a2db69453c5705485 511 Pfam PF01565 FAD binding domain 43 183 7.1E-26 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Tharo_1094 7311369a374ce6a1d0d777868ec0f777 487 Pfam PF03773 Predicted permease 18 448 1.9E-70 T 14-10-2018 IPR005524 Predicted permease DUF318 Tharo_1123 65f58409dfcdb0c2e890d20971fbf5b3 614 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 40 158 3.5E-14 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Tharo_1123 65f58409dfcdb0c2e890d20971fbf5b3 614 SUPERFAMILY SSF56645 38 282 2.36E-55 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Tharo_1123 65f58409dfcdb0c2e890d20971fbf5b3 614 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 285 450 5.1E-28 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Tharo_1123 65f58409dfcdb0c2e890d20971fbf5b3 614 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 4.1E-13 T 14-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria Tharo_1123 65f58409dfcdb0c2e890d20971fbf5b3 614 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 163 271 5.7E-15 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Tharo_1123 65f58409dfcdb0c2e890d20971fbf5b3 614 SUPERFAMILY SSF47203 284 459 1.24E-45 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Tharo_1123 65f58409dfcdb0c2e890d20971fbf5b3 614 Gene3D G3DSA:1.10.540.10 26 159 5.3E-17 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Tharo_1123 65f58409dfcdb0c2e890d20971fbf5b3 614 Gene3D G3DSA:2.40.110.10 161 289 2.3E-25 T 14-10-2018 Tharo_1123 65f58409dfcdb0c2e890d20971fbf5b3 614 Gene3D G3DSA:1.20.140.10 290 457 2.3E-48 T 14-10-2018 Tharo_1123 65f58409dfcdb0c2e890d20971fbf5b3 614 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 466 607 3.3E-24 T 14-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain Tharo_2390 904c76c912a838244f0dc2687860286e 138 SUPERFAMILY SSF52821 27 135 6.16E-34 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Tharo_2390 904c76c912a838244f0dc2687860286e 138 Gene3D G3DSA:3.40.250.10 25 138 2.2E-30 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily Tharo_2390 904c76c912a838244f0dc2687860286e 138 Pfam PF00581 Rhodanese-like domain 39 129 1.5E-20 T 14-10-2018 IPR001763 Rhodanese-like domain Tharo_2390 904c76c912a838244f0dc2687860286e 138 SMART SM00450 35 132 2.2E-26 T 14-10-2018 IPR001763 Rhodanese-like domain Tharo_0916 dd5c737c304a18f84e724cc444b08ac8 312 Gene3D G3DSA:3.40.50.150 10 307 7.0E-103 T 14-10-2018 Tharo_0916 dd5c737c304a18f84e724cc444b08ac8 312 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 7 308 37.764 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 Tharo_0916 dd5c737c304a18f84e724cc444b08ac8 312 Gene3D G3DSA:1.10.150.170 111 213 7.0E-103 T 14-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 Tharo_0916 dd5c737c304a18f84e724cc444b08ac8 312 Pfam PF01795 MraW methylase family 6 307 5.7E-103 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 Tharo_0916 dd5c737c304a18f84e724cc444b08ac8 312 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 5 307 1.6E-105 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 Tharo_0916 dd5c737c304a18f84e724cc444b08ac8 312 SUPERFAMILY SSF53335 6 307 6.01E-47 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_0916 dd5c737c304a18f84e724cc444b08ac8 312 SUPERFAMILY SSF81799 113 212 3.14E-31 T 14-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 Tharo_0916 dd5c737c304a18f84e724cc444b08ac8 312 PIRSF PIRSF004486 1 309 1.7E-96 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 Tharo_1528 8a4d0a101d51987d29d8f421670c7504 214 Pfam PF09997 Predicted membrane protein (DUF2238) 45 185 4.3E-51 T 14-10-2018 IPR014509 Uncharacterised conserved protein UCP020606 Tharo_1528 8a4d0a101d51987d29d8f421670c7504 214 PIRSF PIRSF020606 7 207 6.3E-65 T 14-10-2018 IPR014509 Uncharacterised conserved protein UCP020606 Tharo_0286 cfb89031df9c01d2c4ed07586d765027 400 Pfam PF03594 Benzoate membrane transport protein 1 370 2.4E-129 T 14-10-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 Tharo_0286 cfb89031df9c01d2c4ed07586d765027 400 TIGRFAM TIGR00843 benE: benzoate transporter 2 371 1.3E-112 T 14-10-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 Tharo_3359 1133f8aa73712f1d9a486a83563b80f5 477 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 373 476 6.0E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_3359 1133f8aa73712f1d9a486a83563b80f5 477 Gene3D G3DSA:3.30.565.10 329 477 2.2E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_3359 1133f8aa73712f1d9a486a83563b80f5 477 SMART SM00387 371 477 2.0E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_3359 1133f8aa73712f1d9a486a83563b80f5 477 SUPERFAMILY SSF55874 333 475 1.44E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_3359 1133f8aa73712f1d9a486a83563b80f5 477 Gene3D G3DSA:1.10.287.130 202 307 2.7E-5 T 14-10-2018 Tharo_3359 1133f8aa73712f1d9a486a83563b80f5 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 456 6.5E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3359 1133f8aa73712f1d9a486a83563b80f5 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 421 6.5E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3014 0540d5f6973ff2c57f30d2563a96f963 383 SUPERFAMILY SSF51395 2 360 4.88E-82 T 14-10-2018 Tharo_3014 0540d5f6973ff2c57f30d2563a96f963 383 Pfam PF01070 FMN-dependent dehydrogenase 2 364 2.5E-122 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 Tharo_3014 0540d5f6973ff2c57f30d2563a96f963 383 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 262 268 - T 14-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 Tharo_3014 0540d5f6973ff2c57f30d2563a96f963 383 PIRSF PIRSF000138 1 370 1.1E-115 T 14-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 Tharo_3014 0540d5f6973ff2c57f30d2563a96f963 383 Gene3D G3DSA:3.20.20.70 1 369 3.2E-116 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_0613 cbbffd16001ccb1db1e31ec7660d1a73 191 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 12 182 2.1E-30 T 14-10-2018 IPR010664 Lipopolysaccharide assembly, LptC-related Tharo_0613 cbbffd16001ccb1db1e31ec7660d1a73 191 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 6 182 8.9E-40 T 14-10-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 Tharo_3383 e66b3b4438a619ab4d849ba1c957c154 468 Gene3D G3DSA:3.40.640.10 140 358 3.0E-103 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_3383 e66b3b4438a619ab4d849ba1c957c154 468 SUPERFAMILY SSF46785 2 70 6.57E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_3383 e66b3b4438a619ab4d849ba1c957c154 468 Gene3D G3DSA:3.90.1150.10 93 464 3.0E-103 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_3383 e66b3b4438a619ab4d849ba1c957c154 468 Gene3D G3DSA:1.10.10.10 1 92 4.1E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_3383 e66b3b4438a619ab4d849ba1c957c154 468 Pfam PF00155 Aminotransferase class I and II 144 458 6.9E-29 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Tharo_3383 e66b3b4438a619ab4d849ba1c957c154 468 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 3.2E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_3383 e66b3b4438a619ab4d849ba1c957c154 468 SMART SM00345 7 66 3.5E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Tharo_3383 e66b3b4438a619ab4d849ba1c957c154 468 SUPERFAMILY SSF53383 90 466 1.34E-93 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_2453 381add73f07e89eb718bb157b6d4c571 337 Gene3D G3DSA:3.40.718.10 7 335 7.0E-119 T 14-10-2018 Tharo_2453 381add73f07e89eb718bb157b6d4c571 337 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 38 328 3.0E-105 T 14-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 Tharo_2453 381add73f07e89eb718bb157b6d4c571 337 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 11 332 9.9E-124 T 14-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 Tharo_2453 381add73f07e89eb718bb157b6d4c571 337 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 9 335 36.16 T 14-10-2018 IPR037510 4-hydroxythreonine-4-phosphate dehydrogenase GO:0042823|GO:0050570 KEGG: 00750+1.1.1.262 Tharo_2453 381add73f07e89eb718bb157b6d4c571 337 SUPERFAMILY SSF53659 10 334 2.52E-108 T 14-10-2018 Tharo_1390 a1ad876538dc9bd52f7e4c6288f15643 401 SMART SM00052 129 379 3.8E-81 T 14-10-2018 IPR001633 EAL domain Tharo_1390 a1ad876538dc9bd52f7e4c6288f15643 401 SMART SM00448 1 120 4.1E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1390 a1ad876538dc9bd52f7e4c6288f15643 401 Gene3D G3DSA:3.20.20.450 139 396 2.6E-85 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_1390 a1ad876538dc9bd52f7e4c6288f15643 401 Pfam PF00563 EAL domain 140 373 2.5E-69 T 14-10-2018 IPR001633 EAL domain Tharo_1390 a1ad876538dc9bd52f7e4c6288f15643 401 SUPERFAMILY SSF52172 1 130 3.42E-25 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1390 a1ad876538dc9bd52f7e4c6288f15643 401 Gene3D G3DSA:3.40.50.2300 1 131 1.1E-26 T 14-10-2018 Tharo_1390 a1ad876538dc9bd52f7e4c6288f15643 401 SUPERFAMILY SSF141868 141 387 1.15E-77 T 14-10-2018 IPR035919 EAL domain superfamily Tharo_1390 a1ad876538dc9bd52f7e4c6288f15643 401 Pfam PF00072 Response regulator receiver domain 3 120 1.7E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1664 469358a455e15dbdc43279844a275b7f 176 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 19 150 3.6E-40 T 14-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 Tharo_1664 469358a455e15dbdc43279844a275b7f 176 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 21 141 8.8E-38 T 14-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 Tharo_1664 469358a455e15dbdc43279844a275b7f 176 SUPERFAMILY SSF52540 38 145 6.98E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1664 469358a455e15dbdc43279844a275b7f 176 Gene3D G3DSA:3.40.50.300 13 164 3.6E-42 T 14-10-2018 Tharo_2820 dca727f437a65519657dad30634e0e31 224 ProSitePatterns PS00622 LuxR-type HTH domain signature. 174 201 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2820 dca727f437a65519657dad30634e0e31 224 SMART SM00421 157 214 9.8E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2820 dca727f437a65519657dad30634e0e31 224 SUPERFAMILY SSF46894 150 212 3.74E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_2820 dca727f437a65519657dad30634e0e31 224 SUPERFAMILY SSF52172 6 124 5.29E-7 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_2820 dca727f437a65519657dad30634e0e31 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 211 8.8E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2820 dca727f437a65519657dad30634e0e31 224 Gene3D G3DSA:3.40.50.12740 9 215 2.0E-32 T 14-10-2018 Tharo_2820 dca727f437a65519657dad30634e0e31 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 1.6E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2820 dca727f437a65519657dad30634e0e31 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 1.6E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2820 dca727f437a65519657dad30634e0e31 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 1.6E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_0109 834cd078ff29b6402e153e7e798580da 437 Pfam PF07690 Major Facilitator Superfamily 17 315 7.7E-14 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_0109 834cd078ff29b6402e153e7e798580da 437 Gene3D G3DSA:1.20.1250.20 8 419 5.2E-29 T 14-10-2018 Tharo_0109 834cd078ff29b6402e153e7e798580da 437 SUPERFAMILY SSF103473 9 425 7.06E-31 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_1517 fc1f560986bf4228d2377055f6f2a14c 332 SMART SM00382 67 213 0.0076 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1517 fc1f560986bf4228d2377055f6f2a14c 332 Gene3D G3DSA:3.40.50.300 55 234 2.2E-25 T 14-10-2018 Tharo_1517 fc1f560986bf4228d2377055f6f2a14c 332 Pfam PF07728 AAA domain (dynein-related subfamily) 71 193 4.4E-12 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 Tharo_1517 fc1f560986bf4228d2377055f6f2a14c 332 SUPERFAMILY SSF52540 55 288 3.85E-31 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1517 fc1f560986bf4228d2377055f6f2a14c 332 Pfam PF12556 Cobaltochelatase CobS subunit N terminal 14 44 1.2E-15 T 14-10-2018 IPR025865 Cobaltochelatase subunit CobS N-terminal domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 Tharo_1517 fc1f560986bf4228d2377055f6f2a14c 332 TIGRFAM TIGR01650 PD_CobS: cobaltochelatase, CobS subunit 12 323 2.8E-178 T 14-10-2018 IPR006537 Cobaltochelatase subunit CobS KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 Tharo_0773 b82039edda9729db8a6d397d51f0125a 245 Gene3D G3DSA:3.40.50.720 3 196 2.1E-41 T 14-10-2018 Tharo_0773 b82039edda9729db8a6d397d51f0125a 245 Pfam PF00106 short chain dehydrogenase 4 193 4.2E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0773 b82039edda9729db8a6d397d51f0125a 245 SUPERFAMILY SSF51735 4 230 6.61E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_0773 b82039edda9729db8a6d397d51f0125a 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 1.2E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0773 b82039edda9729db8a6d397d51f0125a 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.2E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0773 b82039edda9729db8a6d397d51f0125a 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.2E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_0773 b82039edda9729db8a6d397d51f0125a 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.2E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Tharo_2327 6edb48a5363e35e8f2b9db6de8bf8089 122 Gene3D G3DSA:3.40.50.10600 1 113 1.2E-29 T 14-10-2018 IPR038396 SpoIIAA-like superfamily Tharo_2327 6edb48a5363e35e8f2b9db6de8bf8089 122 SUPERFAMILY SSF52091 5 113 5.49E-32 T 14-10-2018 IPR036513 STAS domain superfamily Tharo_2327 6edb48a5363e35e8f2b9db6de8bf8089 122 Pfam PF11964 SpoIIAA-like 12 112 1.4E-19 T 14-10-2018 IPR021866 SpoIIAA-like Tharo_0519 bae76ec5d45d68801102673da817efab 271 SUPERFAMILY SSF110997 126 185 1.44E-6 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 Tharo_0519 bae76ec5d45d68801102673da817efab 271 Pfam PF05036 Sporulation related domain 126 184 1.1E-5 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 Tharo_1667 979bcf89b1cc2faef754708800cc012d 158 Pfam PF05981 CreA protein 25 150 9.7E-55 T 14-10-2018 IPR010292 Uncharacterised protein family CreA Tharo_1667 979bcf89b1cc2faef754708800cc012d 158 PIRSF PIRSF003174 1 157 1.8E-65 T 14-10-2018 IPR010292 Uncharacterised protein family CreA Tharo_0311 445708fd35e9b9cefa9d969a9638d244 297 Gene3D G3DSA:3.30.460.10 16 156 1.7E-6 T 14-10-2018 Tharo_0311 445708fd35e9b9cefa9d969a9638d244 297 SUPERFAMILY SSF81301 16 110 1.18E-6 T 14-10-2018 Tharo_0496 d0d907cd52b4ba43db69907f0cabb4b3 274 Pfam PF02673 Bacitracin resistance protein BacA 9 258 1.8E-81 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 Tharo_0496 d0d907cd52b4ba43db69907f0cabb4b3 274 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 257 2.4E-78 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 Tharo_0496 d0d907cd52b4ba43db69907f0cabb4b3 274 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 264 17.442 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 Tharo_3348 d96f1cd6dde98ae56a99daaf2c39b7dd 200 SUPERFAMILY SSF48498 82 198 1.31E-21 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Tharo_3348 d96f1cd6dde98ae56a99daaf2c39b7dd 200 SUPERFAMILY SSF46689 4 85 6.16E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_3348 d96f1cd6dde98ae56a99daaf2c39b7dd 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 60 3.4E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_3348 d96f1cd6dde98ae56a99daaf2c39b7dd 200 Gene3D G3DSA:1.10.357.10 9 191 4.0E-40 T 14-10-2018 Tharo_3348 d96f1cd6dde98ae56a99daaf2c39b7dd 200 Pfam PF08359 YsiA-like protein, C-terminal region 68 174 2.6E-4 T 14-10-2018 IPR013570 Transcription regulator YsiA, C-terminal Tharo_1431 5bd22b775e1f3c30c98e620a0c8587b6 420 Gene3D G3DSA:1.20.1250.20 2 185 1.1E-45 T 14-10-2018 Tharo_1431 5bd22b775e1f3c30c98e620a0c8587b6 420 SUPERFAMILY SSF103473 5 400 1.44E-65 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_1431 5bd22b775e1f3c30c98e620a0c8587b6 420 Gene3D G3DSA:1.20.1250.20 191 407 4.2E-59 T 14-10-2018 Tharo_1431 5bd22b775e1f3c30c98e620a0c8587b6 420 Pfam PF07690 Major Facilitator Superfamily 16 366 2.7E-42 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_1870 ed0266e33e37a93048d4e19c2e28c16b 344 Gene3D G3DSA:3.40.190.170 27 344 1.4E-106 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily Tharo_1870 ed0266e33e37a93048d4e19c2e28c16b 344 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 32 315 7.6E-52 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 Tharo_2976 d77d5dd18db00f9c84ef41530ff7f283 318 Pfam PF13460 NAD(P)H-binding 10 206 3.4E-22 T 14-10-2018 IPR016040 NAD(P)-binding domain Tharo_2976 d77d5dd18db00f9c84ef41530ff7f283 318 SUPERFAMILY SSF51735 3 267 4.53E-56 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_2976 d77d5dd18db00f9c84ef41530ff7f283 318 Gene3D G3DSA:3.40.50.720 5 297 3.2E-55 T 14-10-2018 Tharo_0146 fcef636732842fdf2899db0868cf5302 315 PIRSF PIRSF005963 2 314 1.2E-129 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Tharo_0146 fcef636732842fdf2899db0868cf5302 315 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 24 67 1.0E-8 T 14-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Tharo_0146 fcef636732842fdf2899db0868cf5302 315 TIGRFAM TIGR00510 lipA: lipoyl synthase 25 308 1.8E-130 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Tharo_0146 fcef636732842fdf2899db0868cf5302 315 Hamap MF_00206 Lipoyl synthase [lipA]. 1 315 158.154 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Tharo_0146 fcef636732842fdf2899db0868cf5302 315 SUPERFAMILY SSF102114 44 310 2.35E-71 T 14-10-2018 Tharo_0146 fcef636732842fdf2899db0868cf5302 315 SMART SM00729 78 283 2.8E-14 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Tharo_0146 fcef636732842fdf2899db0868cf5302 315 Gene3D G3DSA:3.20.20.70 40 288 3.7E-21 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_0146 fcef636732842fdf2899db0868cf5302 315 Pfam PF04055 Radical SAM superfamily 85 245 4.2E-16 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_1421 2314d3d5b6c8b14d1c35e3ff983c75f9 201 SUPERFAMILY SSF81452 20 200 6.67E-41 T 14-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_1421 2314d3d5b6c8b14d1c35e3ff983c75f9 201 Pfam PF00510 Cytochrome c oxidase subunit III 68 199 2.0E-5 T 14-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_1421 2314d3d5b6c8b14d1c35e3ff983c75f9 201 Gene3D G3DSA:1.20.120.80 22 201 2.5E-37 T 14-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_1050 66c1f1c390c19f1056ffe54fac9a0e46 490 Gene3D G3DSA:1.10.287.130 209 323 3.8E-23 T 14-10-2018 Tharo_1050 66c1f1c390c19f1056ffe54fac9a0e46 490 SMART SM00388 258 323 1.4E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1050 66c1f1c390c19f1056ffe54fac9a0e46 490 Gene3D G3DSA:3.30.565.10 329 480 1.6E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1050 66c1f1c390c19f1056ffe54fac9a0e46 490 Pfam PF08521 Two-component sensor kinase N-terminal 36 180 3.5E-37 T 14-10-2018 IPR013727 Two-component sensor kinase, N-terminal Tharo_1050 66c1f1c390c19f1056ffe54fac9a0e46 490 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 370 476 2.3E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1050 66c1f1c390c19f1056ffe54fac9a0e46 490 Pfam PF00512 His Kinase A (phospho-acceptor) domain 259 322 1.2E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_1050 66c1f1c390c19f1056ffe54fac9a0e46 490 SMART SM00304 205 257 1.5E-4 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Tharo_1050 66c1f1c390c19f1056ffe54fac9a0e46 490 SMART SM00387 369 478 2.6E-32 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_1050 66c1f1c390c19f1056ffe54fac9a0e46 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 455 2.0E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1050 66c1f1c390c19f1056ffe54fac9a0e46 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 419 2.0E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1050 66c1f1c390c19f1056ffe54fac9a0e46 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 433 2.0E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1050 66c1f1c390c19f1056ffe54fac9a0e46 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 475 2.0E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_1050 66c1f1c390c19f1056ffe54fac9a0e46 490 SUPERFAMILY SSF55874 312 479 6.68E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_1050 66c1f1c390c19f1056ffe54fac9a0e46 490 SUPERFAMILY SSF47384 241 322 1.47E-19 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_0203 4344fc66cb6279bbbdc603a56f1edab9 216 SUPERFAMILY SSF53098 2 158 1.18E-36 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_0203 4344fc66cb6279bbbdc603a56f1edab9 216 Pfam PF00665 Integrase core domain 2 109 1.2E-17 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Tharo_0203 4344fc66cb6279bbbdc603a56f1edab9 216 Gene3D G3DSA:3.30.420.10 5 153 2.9E-9 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_0083 efd99d25972c420fb6ba5efa5d1e9e7d 309 Pfam PF05572 Pregnancy-associated plasma protein-A 217 299 8.2E-11 T 14-10-2018 IPR008754 Peptidase M43, pregnancy-associated plasma-A Reactome: R-HSA-381426 Tharo_0083 efd99d25972c420fb6ba5efa5d1e9e7d 309 Gene3D G3DSA:3.40.390.10 82 307 8.0E-69 T 14-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 Tharo_0083 efd99d25972c420fb6ba5efa5d1e9e7d 309 SUPERFAMILY SSF55486 104 288 1.72E-23 T 14-10-2018 Tharo_1270 121f9d85047958c3b136ad26d530cf51 334 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 1 317 2.6E-108 T 14-10-2018 IPR011303 Ion-translocating oxidoreductase complex Rnf, subunit D GO:0016021|GO:0022900 Tharo_1270 121f9d85047958c3b136ad26d530cf51 334 Pfam PF03116 NQR2, RnfD, RnfE family 1 316 5.7E-103 T 14-10-2018 IPR004338 Ion-translocating oxidoreductase NqrB/RnfD GO:0016020|GO:0055085 Tharo_1270 121f9d85047958c3b136ad26d530cf51 334 Hamap MF_00462 Ion-translocating oxidoreductase complex subunit D [rsxD]. 1 318 25.39 T 14-10-2018 IPR011303 Ion-translocating oxidoreductase complex Rnf, subunit D GO:0016021|GO:0022900 Tharo_2028 0256d4334cc23d04a7f6eb0c230a6fd0 848 Pfam PF12704 MacB-like periplasmic core domain 493 688 8.6E-8 T 14-10-2018 IPR025857 MacB-like periplasmic core domain Tharo_2028 0256d4334cc23d04a7f6eb0c230a6fd0 848 Pfam PF02687 FtsX-like permease family 746 837 1.8E-9 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Tharo_2028 0256d4334cc23d04a7f6eb0c230a6fd0 848 Pfam PF02687 FtsX-like permease family 293 393 6.9E-11 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Tharo_1126 bc040a186d214189c04765a7a1e41738 406 Gene3D G3DSA:3.40.630.10 25 351 4.5E-78 T 14-10-2018 Tharo_1126 bc040a186d214189c04765a7a1e41738 406 SUPERFAMILY SSF101821 84 196 6.11E-24 T 14-10-2018 Tharo_1126 bc040a186d214189c04765a7a1e41738 406 Gene3D G3DSA:2.40.30.40 87 181 4.5E-78 T 14-10-2018 IPR023367 Peptidase M42, domain 2 Tharo_1126 bc040a186d214189c04765a7a1e41738 406 SUPERFAMILY SSF53187 18 353 7.74E-47 T 14-10-2018 Tharo_1126 bc040a186d214189c04765a7a1e41738 406 Pfam PF05343 M42 glutamyl aminopeptidase 59 347 5.2E-66 T 14-10-2018 IPR008007 Peptidase M42 Tharo_1126 bc040a186d214189c04765a7a1e41738 406 TIGRFAM TIGR03106 trio_M42_hydro: hydrolase, peptidase M42 family 14 355 3.9E-176 T 14-10-2018 IPR017537 Peptidase M42, hydrolase Tharo_3144 98ee40239b8d65ebf21f91aee26af8fb 79 Gene3D G3DSA:3.40.1620.10 1 39 4.9E-11 T 14-10-2018 Tharo_3144 98ee40239b8d65ebf21f91aee26af8fb 79 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 42 3.2E-11 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Tharo_3144 98ee40239b8d65ebf21f91aee26af8fb 79 SUPERFAMILY SSF143120 1 46 3.66E-11 T 14-10-2018 IPR036165 YefM-like superfamily Tharo_3144 98ee40239b8d65ebf21f91aee26af8fb 79 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 44 1.3E-6 T 14-10-2018 Tharo_0811 ef4ad84151000b6b2093f8fd72afac72 134 Pfam PF01850 PIN domain 1 117 1.1E-11 T 14-10-2018 IPR002716 PIN domain Tharo_0811 ef4ad84151000b6b2093f8fd72afac72 134 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 1 131 9.515 T 14-10-2018 IPR022907 VapC family GO:0004540 Tharo_0811 ef4ad84151000b6b2093f8fd72afac72 134 SUPERFAMILY SSF88723 1 132 2.02E-25 T 14-10-2018 IPR029060 PIN-like domain superfamily Tharo_0811 ef4ad84151000b6b2093f8fd72afac72 134 Gene3D G3DSA:3.40.50.1010 1 133 3.6E-36 T 14-10-2018 Tharo_1261 7fe0a32c09df4ec8117c69f5c27208bd 250 Gene3D G3DSA:1.20.1260.10 1 250 1.2E-103 T 14-10-2018 IPR012347 Ferritin-like Tharo_1261 7fe0a32c09df4ec8117c69f5c27208bd 250 SUPERFAMILY SSF47240 4 244 2.43E-83 T 14-10-2018 IPR009078 Ferritin-like superfamily Tharo_1261 7fe0a32c09df4ec8117c69f5c27208bd 250 PIRSF PIRSF037834 1 250 5.1E-105 T 14-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 Tharo_1261 7fe0a32c09df4ec8117c69f5c27208bd 250 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 12 250 1.1E-101 T 14-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 Tharo_1261 7fe0a32c09df4ec8117c69f5c27208bd 250 Pfam PF05138 Phenylacetic acid catabolic protein 3 250 2.2E-100 T 14-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 Tharo_0395 29a5189d4850454a4a35bb7c2a147d45 290 TIGRFAM TIGR03818 MotA1: flagellar motor stator protein MotA 4 281 5.4E-112 T 14-10-2018 IPR022522 Flagellar motor stator, MotA Tharo_0395 29a5189d4850454a4a35bb7c2a147d45 290 Pfam PF01618 MotA/TolQ/ExbB proton channel family 138 238 4.6E-11 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel Tharo_0395 29a5189d4850454a4a35bb7c2a147d45 290 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 205 222 - T 14-10-2018 IPR000540 Flagellar motor protein MotA, conserved site Tharo_1317 491c4d610863625c09637810e29261d6 155 Pfam PF02643 Uncharacterized ACR, COG1430 45 146 3.5E-31 T 14-10-2018 IPR003795 Protein of unknown function DUF192 Tharo_1317 491c4d610863625c09637810e29261d6 155 Gene3D G3DSA:2.60.120.1140 33 151 1.3E-35 T 14-10-2018 IPR038695 Saro_0823-like superfamily Tharo_2378 dd9f804e06b654d3ffb5a33857ae7150 216 PIRSF PIRSF000709 1 164 4.8E-17 T 14-10-2018 Tharo_2378 dd9f804e06b654d3ffb5a33857ae7150 216 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 9 202 5.9E-67 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Tharo_2378 dd9f804e06b654d3ffb5a33857ae7150 216 SUPERFAMILY SSF53254 8 209 1.3E-61 T 14-10-2018 IPR029033 Histidine phosphatase superfamily Tharo_2378 dd9f804e06b654d3ffb5a33857ae7150 216 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 11 20 - T 14-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 Tharo_2378 dd9f804e06b654d3ffb5a33857ae7150 216 Gene3D G3DSA:3.40.50.1240 7 214 9.0E-66 T 14-10-2018 IPR029033 Histidine phosphatase superfamily Tharo_2378 dd9f804e06b654d3ffb5a33857ae7150 216 SMART SM00855 8 163 6.8E-23 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Tharo_0987 738eaae815e8a2ce732c54ea31cdf97c 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 2.5E-37 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Tharo_0987 738eaae815e8a2ce732c54ea31cdf97c 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 2.5E-37 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Tharo_0987 738eaae815e8a2ce732c54ea31cdf97c 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 2.5E-37 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Tharo_0987 738eaae815e8a2ce732c54ea31cdf97c 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 2.5E-37 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Tharo_0987 738eaae815e8a2ce732c54ea31cdf97c 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 2.5E-37 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Tharo_0987 738eaae815e8a2ce732c54ea31cdf97c 141 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 14-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Tharo_0987 738eaae815e8a2ce732c54ea31cdf97c 141 SMART SM00562 3 140 1.8E-79 T 14-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Tharo_0987 738eaae815e8a2ce732c54ea31cdf97c 141 Pfam PF00334 Nucleoside diphosphate kinase 4 135 8.6E-55 T 14-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Tharo_0987 738eaae815e8a2ce732c54ea31cdf97c 141 Gene3D G3DSA:3.30.70.141 1 141 1.8E-59 T 14-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Tharo_0987 738eaae815e8a2ce732c54ea31cdf97c 141 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 34.14 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Tharo_0987 738eaae815e8a2ce732c54ea31cdf97c 141 SUPERFAMILY SSF54919 1 139 1.57E-56 T 14-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Tharo_1679 015154f0dd184e15fa08b8a2f3d0f769 167 SUPERFAMILY SSF52172 36 163 2.42E-24 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1679 015154f0dd184e15fa08b8a2f3d0f769 167 Gene3D G3DSA:3.40.50.2300 30 166 3.5E-23 T 14-10-2018 Tharo_1679 015154f0dd184e15fa08b8a2f3d0f769 167 SMART SM00448 38 153 1.5E-12 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1679 015154f0dd184e15fa08b8a2f3d0f769 167 Pfam PF00072 Response regulator receiver domain 40 149 5.6E-16 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_3018 c7d2b1dab4941fb4dbbf1cc647940724 757 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 255 583 2.5E-32 T 14-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core Tharo_3018 c7d2b1dab4941fb4dbbf1cc647940724 757 Gene3D G3DSA:3.40.50.300 225 430 4.3E-15 T 14-10-2018 Tharo_3018 c7d2b1dab4941fb4dbbf1cc647940724 757 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 27 184 9.7E-29 T 14-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain Tharo_3018 c7d2b1dab4941fb4dbbf1cc647940724 757 Pfam PF01966 HD domain 30 109 6.2E-5 T 14-10-2018 IPR006674 HD domain Tharo_3018 c7d2b1dab4941fb4dbbf1cc647940724 757 Gene3D G3DSA:3.40.50.300 436 606 4.9E-11 T 14-10-2018 Tharo_3018 c7d2b1dab4941fb4dbbf1cc647940724 757 Pfam PF00270 DEAD/DEAH box helicase 255 419 3.1E-9 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Tharo_3018 c7d2b1dab4941fb4dbbf1cc647940724 757 SUPERFAMILY SSF52540 249 568 8.38E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3018 c7d2b1dab4941fb4dbbf1cc647940724 757 SMART SM00487 227 453 9.5E-4 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Tharo_3018 c7d2b1dab4941fb4dbbf1cc647940724 757 SUPERFAMILY SSF109604 23 183 4.54E-10 T 14-10-2018 Tharo_3018 c7d2b1dab4941fb4dbbf1cc647940724 757 Gene3D G3DSA:1.10.3210.30 19 127 2.9E-10 T 14-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily Tharo_0489 ce08c7af342aecd564be2c944c5720b1 427 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 4 426 104.963 T 14-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 Tharo_0489 ce08c7af342aecd564be2c944c5720b1 427 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 5 425 1.1E-185 T 14-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 Tharo_0489 ce08c7af342aecd564be2c944c5720b1 427 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 235 271 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Tharo_0489 ce08c7af342aecd564be2c944c5720b1 427 SUPERFAMILY SSF53383 3 425 1.99E-129 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_0489 ce08c7af342aecd564be2c944c5720b1 427 Gene3D G3DSA:3.90.1150.10 8 418 1.3E-174 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_0489 ce08c7af342aecd564be2c944c5720b1 427 Gene3D G3DSA:3.40.640.10 70 318 1.3E-174 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_0489 ce08c7af342aecd564be2c944c5720b1 427 Pfam PF00202 Aminotransferase class-III 33 390 3.4E-73 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Tharo_0832 ee942b0f8d10c0e5ebac47b69c554ee0 487 SUPERFAMILY SSF46548 2 154 2.62E-40 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Tharo_0832 ee942b0f8d10c0e5ebac47b69c554ee0 487 Gene3D G3DSA:3.40.50.720 143 263 1.3E-16 T 14-10-2018 Tharo_0832 ee942b0f8d10c0e5ebac47b69c554ee0 487 SUPERFAMILY SSF51971 142 410 2.35E-69 T 14-10-2018 Tharo_0832 ee942b0f8d10c0e5ebac47b69c554ee0 487 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 145 468 1.2E-27 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Tharo_0832 ee942b0f8d10c0e5ebac47b69c554ee0 487 Gene3D G3DSA:3.50.50.60 264 409 4.3E-38 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_0832 ee942b0f8d10c0e5ebac47b69c554ee0 487 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 2.7E-21 T 14-10-2018 Tharo_0832 ee942b0f8d10c0e5ebac47b69c554ee0 487 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 2.7E-21 T 14-10-2018 Tharo_0832 ee942b0f8d10c0e5ebac47b69c554ee0 487 PRINTS PR00419 Adrenodoxin reductase family signature 296 310 2.7E-21 T 14-10-2018 Tharo_0832 ee942b0f8d10c0e5ebac47b69c554ee0 487 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 486 1.7E-224 T 14-10-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 Tharo_0832 ee942b0f8d10c0e5ebac47b69c554ee0 487 Gene3D G3DSA:1.10.1060.10 9 142 2.1E-23 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Tharo_0832 ee942b0f8d10c0e5ebac47b69c554ee0 487 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 131 4.3E-25 T 14-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 Tharo_0832 ee942b0f8d10c0e5ebac47b69c554ee0 487 SUPERFAMILY SSF51971 362 481 8.36E-10 T 14-10-2018 Tharo_1647 2642aa5d685f2fe3aaa53a634442f087 400 Pfam PF07690 Major Facilitator Superfamily 37 293 2.3E-19 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_1647 2642aa5d685f2fe3aaa53a634442f087 400 ProSitePatterns PS00216 Sugar transport proteins signature 1. 60 77 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Tharo_1647 2642aa5d685f2fe3aaa53a634442f087 400 SUPERFAMILY SSF103473 9 395 1.57E-42 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_1647 2642aa5d685f2fe3aaa53a634442f087 400 Gene3D G3DSA:1.20.1250.20 5 192 2.0E-19 T 14-10-2018 Tharo_1647 2642aa5d685f2fe3aaa53a634442f087 400 Gene3D G3DSA:1.20.1250.20 207 396 2.3E-18 T 14-10-2018 Tharo_0616 b2904a0c57cb23736663be5603c55930 242 SUPERFAMILY SSF54523 30 156 5.23E-7 T 14-10-2018 Tharo_3056 063bb8dc48e14384f48c33b71ef8ac15 457 Gene3D G3DSA:3.40.50.1220 272 455 2.4E-78 T 14-10-2018 Tharo_3056 063bb8dc48e14384f48c33b71ef8ac15 457 Pfam PF02233 NAD(P) transhydrogenase beta subunit 6 449 1.0E-166 T 14-10-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 Tharo_3056 063bb8dc48e14384f48c33b71ef8ac15 457 PIRSF PIRSF000204 1 454 3.7E-152 T 14-10-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 Tharo_3056 063bb8dc48e14384f48c33b71ef8ac15 457 SUPERFAMILY SSF52467 280 453 2.37E-69 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Tharo_0215 d3c5d79d579b9c5efad71ebdad98347f 105 Gene3D G3DSA:2.30.30.110 1 105 1.7E-37 T 14-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor Tharo_0215 d3c5d79d579b9c5efad71ebdad98347f 105 ProDom PD012578 PLASMID TOXIN CCDB CYTOTOXIC LETB POST-SEGREGATION SYSTEM CCDB-LIKE GYRASE FUSED-CCDB 18 104 1.0E-10 T 14-10-2018 IPR002712 Toxin CcdB GO:0006276|GO:0008657 Tharo_0215 d3c5d79d579b9c5efad71ebdad98347f 105 SUPERFAMILY SSF50118 3 105 1.24E-28 T 14-10-2018 Tharo_0215 d3c5d79d579b9c5efad71ebdad98347f 105 Pfam PF01845 CcdB protein 3 104 2.4E-34 T 14-10-2018 IPR002712 Toxin CcdB GO:0006276|GO:0008657 Tharo_0941 39062324e9d313d3c3b750d995b8109c 466 PIRSF PIRSF016636 1 466 5.3E-129 T 14-10-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB Tharo_0941 39062324e9d313d3c3b750d995b8109c 466 PIRSF PIRSF500217 1 466 2.4E-127 T 14-10-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 Tharo_0941 39062324e9d313d3c3b750d995b8109c 466 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 135 345 9.8E-25 T 14-10-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT Tharo_2997 5137e8dc63411030939a39fa6f31baea 660 Gene3D G3DSA:3.30.300.30 530 656 1.8E-14 T 14-10-2018 Tharo_2997 5137e8dc63411030939a39fa6f31baea 660 ProSitePatterns PS00455 Putative AMP-binding domain signature. 274 285 - T 14-10-2018 IPR020845 AMP-binding, conserved site Tharo_2997 5137e8dc63411030939a39fa6f31baea 660 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 5 658 6.3E-290 T 14-10-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 Tharo_2997 5137e8dc63411030939a39fa6f31baea 660 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 38 97 1.7E-6 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 Tharo_2997 5137e8dc63411030939a39fa6f31baea 660 Pfam PF00501 AMP-binding enzyme 104 530 1.4E-46 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Tharo_2997 5137e8dc63411030939a39fa6f31baea 660 SUPERFAMILY SSF56801 24 650 2.49E-122 T 14-10-2018 Tharo_2997 5137e8dc63411030939a39fa6f31baea 660 Gene3D G3DSA:3.40.50.12780 77 526 1.3E-57 T 14-10-2018 Tharo_1115 430b64c08c9f7c709e3c104dc81d5de9 346 SUPERFAMILY SSF51182 7 344 3.63E-92 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily Tharo_1115 430b64c08c9f7c709e3c104dc81d5de9 346 Gene3D G3DSA:2.60.120.10 11 346 9.7E-98 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Tharo_1115 430b64c08c9f7c709e3c104dc81d5de9 346 Pfam PF07883 Cupin domain 96 164 3.4E-20 T 14-10-2018 IPR013096 Cupin 2, conserved barrel Tharo_1466 f34fb4476f7e3ff051a1c02b9852eaae 311 PIRSF PIRSF000846 22 310 8.4E-79 T 14-10-2018 IPR009163 ATP adenylyltransferase GO:0003877|GO:0005524|GO:0009117 KEGG: 00230+2.7.7.53|KEGG: 00920+2.7.7.5|MetaCyc: PWY-5279 Tharo_1466 f34fb4476f7e3ff051a1c02b9852eaae 311 Pfam PF09830 ATP adenylyltransferase 246 304 3.3E-17 T 14-10-2018 IPR019200 ATP adenylyltransferase, C-terminal GO:0003877 KEGG: 00230+2.7.7.53|KEGG: 00920+2.7.7.5|MetaCyc: PWY-5279 Tharo_1466 f34fb4476f7e3ff051a1c02b9852eaae 311 Gene3D G3DSA:3.30.428.70 20 311 2.0E-63 T 14-10-2018 Tharo_1466 f34fb4476f7e3ff051a1c02b9852eaae 311 SUPERFAMILY SSF54197 84 177 4.25E-18 T 14-10-2018 IPR036265 HIT-like superfamily Tharo_2185 77390fc964223bdee7024df2a6da29a4 128 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 4 125 9.0E-45 T 14-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 Tharo_2185 77390fc964223bdee7024df2a6da29a4 128 SUPERFAMILY SSF51230 4 124 2.83E-38 T 14-10-2018 IPR011053 Single hybrid motif Tharo_2185 77390fc964223bdee7024df2a6da29a4 128 Pfam PF01597 Glycine cleavage H-protein 8 125 2.1E-42 T 14-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate Tharo_2185 77390fc964223bdee7024df2a6da29a4 128 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 126 39.468 T 14-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 Tharo_2185 77390fc964223bdee7024df2a6da29a4 128 Gene3D G3DSA:2.40.50.100 2 127 9.8E-47 T 14-10-2018 Tharo_2185 77390fc964223bdee7024df2a6da29a4 128 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 Tharo_1786 9edbf7ae6a8c0fe86ee8f8fdcea2daa6 86 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 83 8.8E-27 T 14-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 Tharo_1786 9edbf7ae6a8c0fe86ee8f8fdcea2daa6 86 Gene3D G3DSA:3.30.1070.10 1 83 4.4E-26 T 14-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 Tharo_1786 9edbf7ae6a8c0fe86ee8f8fdcea2daa6 86 SUPERFAMILY SSF55229 35 84 3.01E-14 T 14-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 Tharo_1786 9edbf7ae6a8c0fe86ee8f8fdcea2daa6 86 Pfam PF03776 Septum formation topological specificity factor MinE 14 82 1.8E-23 T 14-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 Tharo_1786 9edbf7ae6a8c0fe86ee8f8fdcea2daa6 86 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 84 17.821 T 14-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 Tharo_1583 e93bc2309400fda9feea6c8a410b7dad 352 Pfam PF13808 DDE_Tnp_1-associated 5 91 3.8E-31 T 14-10-2018 IPR032806 H repeat-associated protein, N-terminal Tharo_1583 e93bc2309400fda9feea6c8a410b7dad 352 Pfam PF01609 Transposase DDE domain 100 337 1.3E-21 T 14-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 Tharo_2553 6e54f0a0893a71c212ee9332deec4830 408 Pfam PF05940 NnrS protein 12 388 1.2E-83 T 14-10-2018 IPR010266 NnrS Tharo_1549 021936f5e95d024f31b7122545b03e64 83 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 38 78 0.005 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 Tharo_1549 021936f5e95d024f31b7122545b03e64 83 Pfam PF00550 Phosphopantetheine attachment site 6 77 2.7E-8 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain Tharo_1549 021936f5e95d024f31b7122545b03e64 83 SUPERFAMILY SSF47336 3 80 1.83E-12 T 14-10-2018 IPR036736 ACP-like superfamily Tharo_1549 021936f5e95d024f31b7122545b03e64 83 Gene3D G3DSA:1.10.1200.10 1 82 1.0E-21 T 14-10-2018 IPR036736 ACP-like superfamily Tharo_0439 f11588af1067e473ef1ad571d0d015fd 277 Pfam PF02219 Methylenetetrahydrofolate reductase 3 274 6.8E-88 T 14-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 Tharo_0439 f11588af1067e473ef1ad571d0d015fd 277 Gene3D G3DSA:3.20.20.220 1 277 1.7E-98 T 14-10-2018 Tharo_0439 f11588af1067e473ef1ad571d0d015fd 277 SUPERFAMILY SSF51730 4 275 4.12E-97 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like Tharo_0439 f11588af1067e473ef1ad571d0d015fd 277 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 5 273 1.2E-98 T 14-10-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 Tharo_1644 1819b53d27d052f09e9dc28322883bde 263 SUPERFAMILY SSF161098 62 245 2.35E-20 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_1644 1819b53d27d052f09e9dc28322883bde 263 Gene3D G3DSA:1.10.3720.10 61 257 3.8E-17 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_1644 1819b53d27d052f09e9dc28322883bde 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 249 8.0E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Tharo_2186 9b91aee82644326001f33776d4d1e750 964 SUPERFAMILY SSF53383 21 443 8.47E-98 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_2186 9b91aee82644326001f33776d4d1e750 964 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 13 962 25.32 T 14-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 Tharo_2186 9b91aee82644326001f33776d4d1e750 964 Gene3D G3DSA:3.40.640.10 100 358 1.4E-103 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_2186 9b91aee82644326001f33776d4d1e750 964 Gene3D G3DSA:3.40.640.10 526 755 6.4E-59 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_2186 9b91aee82644326001f33776d4d1e750 964 Pfam PF02347 Glycine cleavage system P-protein 475 727 1.2E-8 T 14-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 Tharo_2186 9b91aee82644326001f33776d4d1e750 964 Pfam PF02347 Glycine cleavage system P-protein 21 444 4.3E-173 T 14-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 Tharo_2186 9b91aee82644326001f33776d4d1e750 964 SUPERFAMILY SSF53383 477 957 1.02E-97 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_2186 9b91aee82644326001f33776d4d1e750 964 ProSitePatterns PS00018 EF-hand calcium-binding domain. 624 636 - T 14-10-2018 IPR018247 EF-Hand 1, calcium-binding site Tharo_2186 9b91aee82644326001f33776d4d1e750 964 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 22 956 0.0 T 14-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 Tharo_2186 9b91aee82644326001f33776d4d1e750 964 Gene3D G3DSA:3.90.1150.10 771 909 1.9E-40 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_0379 24235a1039b1a7d8e15bf444037f6bbe 341 Pfam PF04754 Putative transposase, YhgA-like 5 173 1.9E-29 T 14-10-2018 IPR006842 Transposase (putative), YhgA-like Tharo_0379 24235a1039b1a7d8e15bf444037f6bbe 341 Pfam PF14261 Domain of unknown function (DUF4351) 270 323 6.0E-8 T 14-10-2018 IPR025587 Domain of unknown function DUF4351 Tharo_3218 9e83c5e91cff7e32dd213cb6d49e2b15 202 SUPERFAMILY SSF52540 13 202 5.54E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3218 9e83c5e91cff7e32dd213cb6d49e2b15 202 PIRSF PIRSF015617 6 202 3.4E-65 T 14-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 Tharo_3218 9e83c5e91cff7e32dd213cb6d49e2b15 202 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 29 202 4.4E-64 T 14-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 Tharo_3218 9e83c5e91cff7e32dd213cb6d49e2b15 202 Gene3D G3DSA:3.40.50.300 11 202 1.0E-61 T 14-10-2018 Tharo_3218 9e83c5e91cff7e32dd213cb6d49e2b15 202 Pfam PF12557 Cob(I)alamin adenosyltransferase N terminal 1 26 1.6E-7 T 14-10-2018 IPR025826 Cob(I)alamin adenosyltransferase N-terminal domain KEGG: 00860+2.5.1.17 Tharo_3218 9e83c5e91cff7e32dd213cb6d49e2b15 202 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 33 202 8.6E-56 T 14-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 Tharo_0414 c2f057a80d96991f716e8e3bbe5e5fb6 107 Gene3D G3DSA:3.40.30.10 4 106 1.3E-30 T 14-10-2018 Tharo_0414 c2f057a80d96991f716e8e3bbe5e5fb6 107 SUPERFAMILY SSF52833 4 103 1.57E-27 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_0414 c2f057a80d96991f716e8e3bbe5e5fb6 107 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 19 89 1.1E-6 T 14-10-2018 Tharo_3278 2704033fe25e98865a9c693c0c29ac3b 113 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 112 7.2E-28 T 14-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 Tharo_3278 2704033fe25e98865a9c693c0c29ac3b 113 PIRSF PIRSF004761 1 113 1.1E-29 T 14-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 Tharo_3278 2704033fe25e98865a9c693c0c29ac3b 113 Gene3D G3DSA:3.30.2320.50 2 109 1.7E-26 T 14-10-2018 Tharo_3278 2704033fe25e98865a9c693c0c29ac3b 113 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 113 19.799 T 14-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 Tharo_3278 2704033fe25e98865a9c693c0c29ac3b 113 Gene3D G3DSA:2.20.28.10 69 102 1.7E-26 T 14-10-2018 Tharo_3278 2704033fe25e98865a9c693c0c29ac3b 113 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 14-10-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site Tharo_0491 eac5b80ad9335749c49adf22d62c993f 247 Pfam PF00912 Transglycosylase 76 240 7.2E-55 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_0491 eac5b80ad9335749c49adf22d62c993f 247 Hamap MF_00766 Biosynthetic peptidoglycan transglycosylase [mtgA]. 24 247 40.097 T 14-10-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_0491 eac5b80ad9335749c49adf22d62c993f 247 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 34 246 1.7E-86 T 14-10-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_0491 eac5b80ad9335749c49adf22d62c993f 247 Gene3D G3DSA:1.10.3810.10 70 246 9.6E-57 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Tharo_0491 eac5b80ad9335749c49adf22d62c993f 247 SUPERFAMILY SSF53955 76 237 7.31E-59 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily Tharo_1566 53b03812c6e83a8a230ec5f33a57df89 78 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 41 58 2.9E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_1566 53b03812c6e83a8a230ec5f33a57df89 78 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 58 78 2.9E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_1566 53b03812c6e83a8a230ec5f33a57df89 78 SUPERFAMILY SSF46689 10 77 1.66E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_1566 53b03812c6e83a8a230ec5f33a57df89 78 PIRSF PIRSF002097 1 78 3.3E-30 T 14-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 Tharo_1566 53b03812c6e83a8a230ec5f33a57df89 78 Gene3D G3DSA:1.10.10.60 1 77 8.7E-24 T 14-10-2018 Tharo_1566 53b03812c6e83a8a230ec5f33a57df89 78 Pfam PF02954 Bacterial regulatory protein, Fis family 35 75 4.3E-14 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Tharo_3161 7d8beff372a7d2a2dbed8e3a68781282 204 Pfam PF02630 SCO1/SenC 52 132 1.4E-9 T 14-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_3161 7d8beff372a7d2a2dbed8e3a68781282 204 Gene3D G3DSA:3.40.30.10 45 198 3.2E-35 T 14-10-2018 Tharo_3161 7d8beff372a7d2a2dbed8e3a68781282 204 SUPERFAMILY SSF52833 46 187 4.26E-28 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_1055 455a98776098ca2884a63931d5ecc4e9 417 SUPERFAMILY SSF51735 158 311 1.23E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1055 455a98776098ca2884a63931d5ecc4e9 417 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 168 302 2.5E-42 T 14-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase Tharo_1055 455a98776098ca2884a63931d5ecc4e9 417 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 95 118 - T 14-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Tharo_1055 455a98776098ca2884a63931d5ecc4e9 417 Gene3D G3DSA:3.30.460.30 2 154 6.5E-57 T 14-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Tharo_1055 455a98776098ca2884a63931d5ecc4e9 417 SUPERFAMILY SSF69742 1 154 3.27E-48 T 14-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Tharo_1055 455a98776098ca2884a63931d5ecc4e9 417 PIRSF PIRSF000445 1 417 1.8E-151 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Tharo_1055 455a98776098ca2884a63931d5ecc4e9 417 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 316 413 2.7E-29 T 14-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Tharo_1055 455a98776098ca2884a63931d5ecc4e9 417 SUPERFAMILY SSF69075 313 413 2.88E-28 T 14-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Tharo_1055 455a98776098ca2884a63931d5ecc4e9 417 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 5 413 2.0E-130 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Tharo_1055 455a98776098ca2884a63931d5ecc4e9 417 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 152 1.3E-49 T 14-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Tharo_1055 455a98776098ca2884a63931d5ecc4e9 417 Gene3D G3DSA:3.40.50.720 157 309 2.1E-43 T 14-10-2018 Tharo_1055 455a98776098ca2884a63931d5ecc4e9 417 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 414 30.145 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 Tharo_0009 bfbd4f630e4bdfddcaa767ad09b8df17 396 Pfam PF09925 Predicted membrane protein (DUF2157) 71 180 7.4E-7 T 14-10-2018 IPR018677 Domain of unknown function DUF2157 Tharo_1490 8fc0412ace62ed845a68f45cf9c6a405 164 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 3 135 1.0E-55 T 14-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 Tharo_1490 8fc0412ace62ed845a68f45cf9c6a405 164 SUPERFAMILY SSF52540 1 162 4.32E-29 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1490 8fc0412ace62ed845a68f45cf9c6a405 164 Gene3D G3DSA:2.20.25.120 47 79 2.5E-62 T 14-10-2018 Tharo_1490 8fc0412ace62ed845a68f45cf9c6a405 164 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 3 158 1.1E-49 T 14-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 Tharo_1490 8fc0412ace62ed845a68f45cf9c6a405 164 Gene3D G3DSA:3.40.50.300 5 157 2.5E-62 T 14-10-2018 Tharo_0612 66a1101aa68ce37aab0546a49a1ef2cd 179 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 21 170 3.0E-46 T 14-10-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 Tharo_0612 66a1101aa68ce37aab0546a49a1ef2cd 179 Gene3D G3DSA:2.60.450.10 23 174 5.8E-48 T 14-10-2018 Tharo_0612 66a1101aa68ce37aab0546a49a1ef2cd 179 Pfam PF03968 OstA-like protein 31 143 2.7E-30 T 14-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal Tharo_0612 66a1101aa68ce37aab0546a49a1ef2cd 179 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 3 170 27.019 T 14-10-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 Tharo_2594 b044a066b201a7ad4afb182115d60864 65 SUPERFAMILY SSF110324 1 61 8.72E-24 T 14-10-2018 Tharo_2594 b044a066b201a7ad4afb182115d60864 65 Gene3D G3DSA:2.40.50.100 1 65 7.6E-29 T 14-10-2018 Tharo_2594 b044a066b201a7ad4afb182115d60864 65 ProSitePatterns PS00831 Ribosomal protein L27 signature. 12 26 - T 14-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2594 b044a066b201a7ad4afb182115d60864 65 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 61 2.3E-27 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2594 b044a066b201a7ad4afb182115d60864 65 PRINTS PR00063 Ribosomal protein L27 signature 32 56 1.5E-22 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2594 b044a066b201a7ad4afb182115d60864 65 PRINTS PR00063 Ribosomal protein L27 signature 7 31 1.5E-22 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2594 b044a066b201a7ad4afb182115d60864 65 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 6 49 3.0E-17 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2594 b044a066b201a7ad4afb182115d60864 65 Pfam PF01016 Ribosomal L27 protein 1 59 1.5E-25 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1130 c80862cc73a28ed57101569690bfa185 202 Pfam PF01814 Hemerythrin HHE cation binding domain 6 140 1.0E-13 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 Tharo_1130 c80862cc73a28ed57101569690bfa185 202 Gene3D G3DSA:1.20.120.520 2 160 8.2E-30 T 14-10-2018 Tharo_2214 296e828990c7ef1b4fb1ef73e1a087fa 348 PIRSF PIRSF006004 1 344 2.9E-88 T 14-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 Tharo_2214 296e828990c7ef1b4fb1ef73e1a087fa 348 Pfam PF04055 Radical SAM superfamily 100 266 2.8E-11 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Tharo_2214 296e828990c7ef1b4fb1ef73e1a087fa 348 SUPERFAMILY SSF102114 99 310 9.94E-15 T 14-10-2018 Tharo_2214 296e828990c7ef1b4fb1ef73e1a087fa 348 Gene3D G3DSA:3.20.20.70 63 317 4.4E-68 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_2159 cff25870bc3f9cc5fcbe9cb1a56474bb 431 Gene3D G3DSA:1.10.443.10 228 423 7.2E-12 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Tharo_2159 cff25870bc3f9cc5fcbe9cb1a56474bb 431 Gene3D G3DSA:1.10.150.130 107 216 5.3E-7 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Tharo_2159 cff25870bc3f9cc5fcbe9cb1a56474bb 431 SUPERFAMILY SSF56349 109 416 5.59E-30 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Tharo_2159 cff25870bc3f9cc5fcbe9cb1a56474bb 431 Pfam PF13356 Arm DNA-binding domain 6 87 4.4E-7 T 14-10-2018 IPR025166 Integrase, DNA-binding domain Tharo_2159 cff25870bc3f9cc5fcbe9cb1a56474bb 431 Gene3D G3DSA:3.30.160.390 7 106 1.5E-7 T 14-10-2018 IPR038488 Integrase, DNA-binding domain superfamily Tharo_0694 d728d17a2805f171117fe9f06ebb9146 148 Pfam PF07511 Protein of unknown function (DUF1525) 35 145 3.5E-42 T 14-10-2018 IPR011090 Integrating conjugative element protein, PFL4709 Tharo_0694 d728d17a2805f171117fe9f06ebb9146 148 TIGRFAM TIGR03757 conj_TIGR03757: integrating conjugative element protein, PFL_4709 family 35 144 2.4E-43 T 14-10-2018 IPR011090 Integrating conjugative element protein, PFL4709 Tharo_3257 c626f22a102e5c3a62f8bacc85641845 696 Pfam PF00884 Sulfatase 301 578 2.5E-46 T 14-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 Tharo_3257 c626f22a102e5c3a62f8bacc85641845 696 Gene3D G3DSA:3.40.720.10 299 580 8.4E-51 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 Tharo_3257 c626f22a102e5c3a62f8bacc85641845 696 PIRSF PIRSF005091 18 679 1.5E-114 T 14-10-2018 IPR012160 Lipoteichoic acid synthase-like Tharo_3257 c626f22a102e5c3a62f8bacc85641845 696 SUPERFAMILY SSF53649 301 662 1.07E-60 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 Tharo_1041 6e1e6167e51441ddca144c3aaae28086 222 Pfam PF00156 Phosphoribosyl transferase domain 7 186 7.5E-30 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Tharo_1041 6e1e6167e51441ddca144c3aaae28086 222 Gene3D G3DSA:3.30.1310.20 53 111 2.6E-63 T 14-10-2018 Tharo_1041 6e1e6167e51441ddca144c3aaae28086 222 Gene3D G3DSA:3.40.50.2020 3 199 2.6E-63 T 14-10-2018 Tharo_1041 6e1e6167e51441ddca144c3aaae28086 222 SUPERFAMILY SSF53271 1 204 2.05E-41 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like Tharo_2752 b663417dd8293fc7d2621bdc0efebe95 385 SUPERFAMILY SSF52540 128 366 2.26E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2752 b663417dd8293fc7d2621bdc0efebe95 385 Gene3D G3DSA:3.40.50.2300 1 123 3.1E-22 T 14-10-2018 Tharo_2752 b663417dd8293fc7d2621bdc0efebe95 385 SUPERFAMILY SSF52172 1 126 4.07E-9 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_2752 b663417dd8293fc7d2621bdc0efebe95 385 Pfam PF13614 AAA domain 129 276 2.7E-12 T 14-10-2018 IPR025669 AAA domain Tharo_2752 b663417dd8293fc7d2621bdc0efebe95 385 Gene3D G3DSA:3.40.50.300 127 367 1.9E-56 T 14-10-2018 Tharo_3082 abc28c334b0692eb51486b21dd2bc234 209 Gene3D G3DSA:3.90.280.10 2 204 5.6E-45 T 14-10-2018 IPR036610 PEBP-like superfamily Tharo_3082 abc28c334b0692eb51486b21dd2bc234 209 SUPERFAMILY SSF49777 6 202 2.75E-40 T 14-10-2018 IPR036610 PEBP-like superfamily Tharo_3082 abc28c334b0692eb51486b21dd2bc234 209 Pfam PF01161 Phosphatidylethanolamine-binding protein 30 200 4.6E-36 T 14-10-2018 IPR008914 Phosphatidylethanolamine-binding protein Tharo_3082 abc28c334b0692eb51486b21dd2bc234 209 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 31 198 3.3E-21 T 14-10-2018 IPR005247 YbhB/YbcL Tharo_1696 2548fb940b9040bffaee9a8be3d9aead 129 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 31 113 2.3E-20 T 14-10-2018 IPR031982 Type IV minor pilin ComP Tharo_1696 2548fb940b9040bffaee9a8be3d9aead 129 Pfam PF07963 Prokaryotic N-terminal methylation motif 5 30 6.6E-10 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Tharo_1696 2548fb940b9040bffaee9a8be3d9aead 129 Gene3D G3DSA:3.30.700.10 10 128 1.1E-25 T 14-10-2018 Tharo_1696 2548fb940b9040bffaee9a8be3d9aead 129 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 30 2.1E-9 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Tharo_1696 2548fb940b9040bffaee9a8be3d9aead 129 SUPERFAMILY SSF54523 10 122 2.2E-24 T 14-10-2018 Tharo_2291 4bba943311df289ff85138c98dbc5050 152 SUPERFAMILY SSF52402 6 152 1.4E-36 T 14-10-2018 Tharo_2291 4bba943311df289ff85138c98dbc5050 152 Pfam PF00582 Universal stress protein family 6 152 5.4E-32 T 14-10-2018 IPR006016 UspA Tharo_2291 4bba943311df289ff85138c98dbc5050 152 Gene3D G3DSA:3.40.50.620 4 152 7.0E-38 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_2291 4bba943311df289ff85138c98dbc5050 152 PRINTS PR01438 Universal stress protein signature 7 25 9.5E-16 T 14-10-2018 IPR006015 Universal stress protein A Tharo_2291 4bba943311df289ff85138c98dbc5050 152 PRINTS PR01438 Universal stress protein signature 112 124 9.5E-16 T 14-10-2018 IPR006015 Universal stress protein A Tharo_2291 4bba943311df289ff85138c98dbc5050 152 PRINTS PR01438 Universal stress protein signature 130 152 9.5E-16 T 14-10-2018 IPR006015 Universal stress protein A Tharo_3367 127f30c11b6f1d1632708255a38a59d4 393 Pfam PF13458 Periplasmic binding protein 32 370 2.3E-72 T 14-10-2018 IPR028081 Leucine-binding protein domain Tharo_3367 127f30c11b6f1d1632708255a38a59d4 393 Gene3D G3DSA:3.40.50.2300 34 361 1.2E-110 T 14-10-2018 Tharo_3367 127f30c11b6f1d1632708255a38a59d4 393 Gene3D G3DSA:3.40.50.2300 150 367 1.2E-110 T 14-10-2018 Tharo_3367 127f30c11b6f1d1632708255a38a59d4 393 SUPERFAMILY SSF53822 33 391 4.06E-91 T 14-10-2018 IPR028082 Periplasmic binding protein-like I Tharo_2332 e06eb614685efbe43e03570a17607d8e 116 Gene3D G3DSA:2.60.300.12 10 116 1.7E-35 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 Tharo_2332 e06eb614685efbe43e03570a17607d8e 116 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 97 114 - T 14-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 Tharo_2332 e06eb614685efbe43e03570a17607d8e 116 Pfam PF01521 Iron-sulphur cluster biosynthesis 11 111 2.7E-20 T 14-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 Tharo_2332 e06eb614685efbe43e03570a17607d8e 116 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 13 116 6.0E-40 T 14-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 Tharo_2332 e06eb614685efbe43e03570a17607d8e 116 SUPERFAMILY SSF89360 11 105 3.14E-33 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 Tharo_2332 e06eb614685efbe43e03570a17607d8e 116 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 116 37.755 T 14-10-2018 IPR023063 FeS cluster insertion protein ErpA GO:0097428 Tharo_3103 cb57f2d224ce7f6034157f396c753f57 236 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 5 236 8.9E-62 T 14-10-2018 IPR010239 Conserved hypothetical protein CHP02001 Tharo_3103 cb57f2d224ce7f6034157f396c753f57 236 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 27 220 2.6E-57 T 14-10-2018 IPR010239 Conserved hypothetical protein CHP02001 Tharo_3103 cb57f2d224ce7f6034157f396c753f57 236 SUPERFAMILY SSF56935 46 198 5.49E-5 T 14-10-2018 Tharo_0917 4b167e9ec68101e63bf0327d49921ba5 88 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 8 84 5.4E-21 T 14-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 Tharo_0917 4b167e9ec68101e63bf0327d49921ba5 88 Pfam PF04999 Cell division protein FtsL 6 85 1.5E-23 T 14-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 Tharo_0917 4b167e9ec68101e63bf0327d49921ba5 88 Hamap MF_00910 Cell division protein FtsL [ftsL]. 1 84 16.617 T 14-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 Tharo_1962 49b7df39c7bd7d531be90ff9b3471f67 314 Pfam PF02470 MlaD protein 45 113 2.5E-12 T 14-10-2018 IPR003399 Mce/MlaD Tharo_0561 2e374bd1f58fb3ae8e994d0555e6e8e4 472 Pfam PF05193 Peptidase M16 inactive domain 213 388 1.5E-35 T 14-10-2018 IPR007863 Peptidase M16, C-terminal Tharo_0561 2e374bd1f58fb3ae8e994d0555e6e8e4 472 SUPERFAMILY SSF63411 43 267 1.62E-41 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Tharo_0561 2e374bd1f58fb3ae8e994d0555e6e8e4 472 Gene3D G3DSA:3.30.830.10 263 457 1.1E-50 T 14-10-2018 Tharo_0561 2e374bd1f58fb3ae8e994d0555e6e8e4 472 Pfam PF00675 Insulinase (Peptidase family M16) 72 205 4.3E-7 T 14-10-2018 IPR011765 Peptidase M16, N-terminal Tharo_0561 2e374bd1f58fb3ae8e994d0555e6e8e4 472 Gene3D G3DSA:3.30.830.10 50 260 3.9E-45 T 14-10-2018 Tharo_0561 2e374bd1f58fb3ae8e994d0555e6e8e4 472 SUPERFAMILY SSF63411 272 453 2.5E-41 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Tharo_1599 fffdacb00cf391de1c8b9b5616dc1976 59 Pfam PF01783 Ribosomal L32p protein family 2 55 5.1E-19 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1599 fffdacb00cf391de1c8b9b5616dc1976 59 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 1.3E-19 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_1599 fffdacb00cf391de1c8b9b5616dc1976 59 SUPERFAMILY SSF57829 2 56 1.34E-17 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 Tharo_1599 fffdacb00cf391de1c8b9b5616dc1976 59 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 17.202 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_3025 105a6adadcf115245c878f1e48450dd1 254 SUPERFAMILY SSF56300 4 228 3.32E-29 T 14-10-2018 Tharo_3025 105a6adadcf115245c878f1e48450dd1 254 Gene3D G3DSA:3.60.21.10 3 239 5.1E-18 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like Tharo_3025 105a6adadcf115245c878f1e48450dd1 254 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 7 220 3.0E-12 T 14-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 Tharo_2876 67f37cf06a660179618efb4638ab81cf 142 Pfam PF02472 Biopolymer transport protein ExbD/TolR 4 136 1.9E-24 T 14-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 Tharo_2876 67f37cf06a660179618efb4638ab81cf 142 Gene3D G3DSA:3.30.420.270 77 133 1.3E-9 T 14-10-2018 Tharo_1829 06e3915d469d63e87ae64c51b4dc0de5 261 SMART SM00382 29 224 6.9E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_1829 06e3915d469d63e87ae64c51b4dc0de5 261 Gene3D G3DSA:3.40.50.300 2 249 3.8E-53 T 14-10-2018 Tharo_1829 06e3915d469d63e87ae64c51b4dc0de5 261 SUPERFAMILY SSF52540 4 244 1.31E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1829 06e3915d469d63e87ae64c51b4dc0de5 261 Pfam PF00005 ABC transporter 22 175 1.6E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_1035 a3224013d7464fa4d9a0d7fcb424768c 417 Gene3D G3DSA:3.50.50.60 103 402 5.2E-51 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1035 a3224013d7464fa4d9a0d7fcb424768c 417 SUPERFAMILY SSF54373 273 363 3.27E-16 T 14-10-2018 Tharo_1035 a3224013d7464fa4d9a0d7fcb424768c 417 Pfam PF01266 FAD dependent oxidoreductase 2 401 7.0E-63 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Tharo_1035 a3224013d7464fa4d9a0d7fcb424768c 417 SUPERFAMILY SSF51905 2 411 9.19E-45 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1035 a3224013d7464fa4d9a0d7fcb424768c 417 Gene3D G3DSA:3.30.9.10 131 362 5.2E-51 T 14-10-2018 Tharo_1035 a3224013d7464fa4d9a0d7fcb424768c 417 Gene3D G3DSA:3.50.50.60 1 66 2.7E-6 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_2440 fef602f907a86bffeeb8a5388e38e818 257 Pfam PF09955 Predicted integral membrane protein (DUF2189) 69 192 5.7E-38 T 14-10-2018 IPR018692 Predicted integral membrane protein DUF2189 Tharo_2302 45a2add056dbe5bf3b77278596cb30b1 260 Pfam PF01925 Sulfite exporter TauE/SafE 14 254 5.5E-36 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 Tharo_2256 b9e0101073bb3bca68443dc8e298ffca 365 Pfam PF03916 Polysulphide reductase, NrfD 10 309 3.1E-34 T 14-10-2018 IPR005614 NrfD family Tharo_2766 00a4fe42492ab839371f3ab4715ba498 227 SUPERFAMILY SSF46894 148 221 2.45E-14 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_2766 00a4fe42492ab839371f3ab4715ba498 227 SMART SM00421 158 217 7.3E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2766 00a4fe42492ab839371f3ab4715ba498 227 Pfam PF00072 Response regulator receiver domain 11 122 6.7E-12 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2766 00a4fe42492ab839371f3ab4715ba498 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 217 2.3E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Tharo_2766 00a4fe42492ab839371f3ab4715ba498 227 SUPERFAMILY SSF52172 9 136 1.08E-15 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_2766 00a4fe42492ab839371f3ab4715ba498 227 SMART SM00448 9 122 8.3E-6 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2766 00a4fe42492ab839371f3ab4715ba498 227 Gene3D G3DSA:3.40.50.12740 9 222 6.3E-37 T 14-10-2018 Tharo_2341 c649784fcc495302e9c0a332191fc048 150 SUPERFAMILY SSF47240 14 148 4.61E-40 T 14-10-2018 IPR009078 Ferritin-like superfamily Tharo_2341 c649784fcc495302e9c0a332191fc048 150 Gene3D G3DSA:1.20.1260.10 9 150 5.3E-54 T 14-10-2018 IPR012347 Ferritin-like Tharo_2341 c649784fcc495302e9c0a332191fc048 150 Pfam PF02915 Rubrerythrin 21 144 1.5E-28 T 14-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 Tharo_1259 ceb7025730a841809063abbf5a745186 330 SUPERFAMILY SSF47240 47 287 5.47E-83 T 14-10-2018 IPR009078 Ferritin-like superfamily Tharo_1259 ceb7025730a841809063abbf5a745186 330 Gene3D G3DSA:1.20.1260.10 21 328 1.3E-128 T 14-10-2018 IPR012347 Ferritin-like Tharo_1259 ceb7025730a841809063abbf5a745186 330 Pfam PF05138 Phenylacetic acid catabolic protein 37 310 6.1E-104 T 14-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 Tharo_1259 ceb7025730a841809063abbf5a745186 330 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 27 314 5.3E-164 T 14-10-2018 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.149 Tharo_0562 f83eaf6ad6a9e304b2db212c9d630851 462 Pfam PF00675 Insulinase (Peptidase family M16) 46 189 1.1E-28 T 14-10-2018 IPR011765 Peptidase M16, N-terminal Tharo_0562 f83eaf6ad6a9e304b2db212c9d630851 462 SUPERFAMILY SSF63411 259 446 2.67E-36 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Tharo_0562 f83eaf6ad6a9e304b2db212c9d630851 462 Gene3D G3DSA:3.30.830.10 252 448 1.8E-55 T 14-10-2018 Tharo_0562 f83eaf6ad6a9e304b2db212c9d630851 462 Pfam PF05193 Peptidase M16 inactive domain 199 379 4.0E-26 T 14-10-2018 IPR007863 Peptidase M16, C-terminal Tharo_0562 f83eaf6ad6a9e304b2db212c9d630851 462 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 64 87 - T 14-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 Tharo_0562 f83eaf6ad6a9e304b2db212c9d630851 462 SUPERFAMILY SSF63411 30 237 1.39E-61 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Tharo_0562 f83eaf6ad6a9e304b2db212c9d630851 462 Gene3D G3DSA:3.30.830.10 29 250 3.8E-83 T 14-10-2018 Tharo_1107 e53e873a81b35b96c78134bd6507bddd 341 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 30 314 2.2E-56 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 Tharo_1107 e53e873a81b35b96c78134bd6507bddd 341 Gene3D G3DSA:3.40.190.170 25 341 2.1E-105 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily Tharo_1107 e53e873a81b35b96c78134bd6507bddd 341 SUPERFAMILY SSF53850 134 274 2.71E-6 T 14-10-2018 Tharo_2708 0b494f839664ef1ea394360473725f3e 117 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 1 117 4.1E-40 T 14-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2708 0b494f839664ef1ea394360473725f3e 117 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 3 117 8.7E-39 T 14-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2708 0b494f839664ef1ea394360473725f3e 117 SUPERFAMILY SSF53137 3 115 6.32E-53 T 14-10-2018 Tharo_2708 0b494f839664ef1ea394360473725f3e 117 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 117 26.558 T 14-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2708 0b494f839664ef1ea394360473725f3e 117 Gene3D G3DSA:3.30.420.100 1 117 2.5E-43 T 14-10-2018 Tharo_2964 86620d6b41b7c81f6ac3eebb13653ff0 152 Pfam PF04608 Phosphatidylglycerophosphatase A 5 146 1.9E-47 T 14-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 Tharo_2964 86620d6b41b7c81f6ac3eebb13653ff0 152 SUPERFAMILY SSF101307 1 146 9.03E-34 T 14-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 Tharo_2964 86620d6b41b7c81f6ac3eebb13653ff0 152 PIRSF PIRSF006162 1 152 3.9E-42 T 14-10-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 Tharo_1334 653cc20121973c9646431d31680feded 526 Pfam PF01384 Phosphate transporter family 63 513 5.8E-108 T 14-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 Tharo_1406 8c0ce748fb3d40a36f289faab1cc2e77 514 Pfam PF00221 Aromatic amino acid lyase 10 473 5.8E-179 T 14-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 Tharo_1406 8c0ce748fb3d40a36f289faab1cc2e77 514 Gene3D G3DSA:1.10.275.10 1 196 1.2E-64 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal Tharo_1406 8c0ce748fb3d40a36f289faab1cc2e77 514 SUPERFAMILY SSF48557 3 505 3.22E-182 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 Tharo_1406 8c0ce748fb3d40a36f289faab1cc2e77 514 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 2 507 43.872 T 14-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 Tharo_1406 8c0ce748fb3d40a36f289faab1cc2e77 514 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 4 508 1.2E-213 T 14-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 Tharo_1406 8c0ce748fb3d40a36f289faab1cc2e77 514 Gene3D G3DSA:1.20.200.10 197 512 5.4E-120 T 14-10-2018 Tharo_1714 b23a5abed8ea863f1d1948822ae03ed6 738 Gene3D G3DSA:3.30.450.20 129 292 1.8E-5 T 14-10-2018 Tharo_1714 b23a5abed8ea863f1d1948822ae03ed6 738 Pfam PF00929 Exonuclease 550 706 5.4E-33 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Tharo_1714 b23a5abed8ea863f1d1948822ae03ed6 738 SMART SM00479 547 715 9.6E-50 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Tharo_1714 b23a5abed8ea863f1d1948822ae03ed6 738 Gene3D G3DSA:3.30.420.10 541 711 1.3E-48 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_1714 b23a5abed8ea863f1d1948822ae03ed6 738 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 541 713 1.1E-31 T 14-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Tharo_1714 b23a5abed8ea863f1d1948822ae03ed6 738 SUPERFAMILY SSF53098 543 724 1.12E-52 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_2053 483d0c7b74fe60b3ba43e4f0f7555c07 212 Gene3D G3DSA:3.30.420.10 11 209 4.8E-69 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_2053 483d0c7b74fe60b3ba43e4f0f7555c07 212 Hamap MF_00052_B Ribonuclease HII [rnhB]. 19 202 33.66 T 14-10-2018 IPR022898 Ribonuclease HII GO:0004523 Tharo_2053 483d0c7b74fe60b3ba43e4f0f7555c07 212 Pfam PF01351 Ribonuclease HII 21 201 8.5E-36 T 14-10-2018 IPR024567 Ribonuclease HII/HIII domain Tharo_2053 483d0c7b74fe60b3ba43e4f0f7555c07 212 SUPERFAMILY SSF53098 18 207 9.26E-65 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_1657 416496377bfcc7cc5bee6a046e7e9733 108 SUPERFAMILY SSF52833 4 102 2.46E-27 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_1657 416496377bfcc7cc5bee6a046e7e9733 108 Gene3D G3DSA:3.40.30.10 4 107 1.4E-31 T 14-10-2018 Tharo_1657 416496377bfcc7cc5bee6a046e7e9733 108 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 23 89 5.3E-8 T 14-10-2018 Tharo_0307 8c3c43e769e3225a4487fbdc4ef08e3f 136 TIGRFAM TIGR03750 conj_TIGR03750: conjugative transfer region protein, TIGR03750 family 14 129 2.3E-42 T 14-10-2018 IPR021877 Protein of unknown function DUF3487 Tharo_0307 8c3c43e769e3225a4487fbdc4ef08e3f 136 Pfam PF11990 Protein of unknown function (DUF3487) 13 130 1.3E-42 T 14-10-2018 IPR021877 Protein of unknown function DUF3487 Tharo_1127 01ea24888cce819c01de92346837fbc8 442 SUPERFAMILY SSF56935 92 442 3.51E-57 T 14-10-2018 Tharo_1127 01ea24888cce819c01de92346837fbc8 442 Pfam PF13609 Gram-negative porin 74 410 7.3E-32 T 14-10-2018 Tharo_1127 01ea24888cce819c01de92346837fbc8 442 Gene3D G3DSA:2.40.160.10 91 442 6.9E-56 T 14-10-2018 IPR023614 Porin domain superfamily Tharo_3255 962b37272d27c56057b3ebffd63231dc 222 SUPERFAMILY SSF46894 123 220 3.12E-16 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_3255 962b37272d27c56057b3ebffd63231dc 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 219 2.1E-12 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_3255 962b37272d27c56057b3ebffd63231dc 222 SUPERFAMILY SSF52172 1 124 2.13E-33 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_3255 962b37272d27c56057b3ebffd63231dc 222 SMART SM00448 1 112 6.3E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_3255 962b37272d27c56057b3ebffd63231dc 222 Gene3D G3DSA:3.40.50.2300 1 119 7.2E-33 T 14-10-2018 Tharo_3255 962b37272d27c56057b3ebffd63231dc 222 Gene3D G3DSA:1.10.10.10 120 221 1.3E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_3255 962b37272d27c56057b3ebffd63231dc 222 SMART SM00862 146 219 7.6E-15 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_3255 962b37272d27c56057b3ebffd63231dc 222 Pfam PF00072 Response regulator receiver domain 4 111 5.8E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_0623 50d981a9b65c5a7cb66e8cd1fb121070 282 Gene3D G3DSA:3.40.50.300 18 265 4.4E-67 T 14-10-2018 Tharo_0623 50d981a9b65c5a7cb66e8cd1fb121070 282 SMART SM00382 45 234 2.6E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_0623 50d981a9b65c5a7cb66e8cd1fb121070 282 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_0623 50d981a9b65c5a7cb66e8cd1fb121070 282 SUPERFAMILY SSF52540 19 249 1.27E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0623 50d981a9b65c5a7cb66e8cd1fb121070 282 Pfam PF00005 ABC transporter 36 185 6.5E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_2393 7241bc19d8f53e9b7028bc956f53e922 159 Gene3D G3DSA:2.30.30.40 96 156 1.1E-6 T 14-10-2018 Tharo_2393 7241bc19d8f53e9b7028bc956f53e922 159 Pfam PF06347 Bacterial SH3 domain 103 158 1.6E-6 T 14-10-2018 IPR010466 Protein of unknown function DUF1058 Tharo_2393 7241bc19d8f53e9b7028bc956f53e922 159 Pfam PF06347 Bacterial SH3 domain 44 94 4.8E-11 T 14-10-2018 IPR010466 Protein of unknown function DUF1058 Tharo_2393 7241bc19d8f53e9b7028bc956f53e922 159 Gene3D G3DSA:2.30.30.40 34 95 3.3E-5 T 14-10-2018 Tharo_1251 cd7e68cc4ecb0b76e65bba6b80f7d4ba 100 Pfam PF01910 Thiamine-binding protein 5 95 5.1E-35 T 14-10-2018 IPR002767 Thiamine-binding protein Tharo_1251 cd7e68cc4ecb0b76e65bba6b80f7d4ba 100 Gene3D G3DSA:3.30.70.930 1 99 2.6E-39 T 14-10-2018 IPR029756 MTH1187/YkoF-like Tharo_1251 cd7e68cc4ecb0b76e65bba6b80f7d4ba 100 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 3 95 5.6E-37 T 14-10-2018 IPR002767 Thiamine-binding protein Tharo_1251 cd7e68cc4ecb0b76e65bba6b80f7d4ba 100 SUPERFAMILY SSF89957 1 97 8.24E-36 T 14-10-2018 IPR029756 MTH1187/YkoF-like Tharo_1533 6dbb49a090eb0795446ccfeec8a3aab5 326 Pfam PF02661 Fic/DOC family 79 181 3.8E-16 T 14-10-2018 IPR003812 Fido domain Tharo_1533 6dbb49a090eb0795446ccfeec8a3aab5 326 Pfam PF13776 Domain of unknown function (DUF4172) 17 48 1.7E-11 T 14-10-2018 IPR025230 Domain of unknown function DUF4172 Tharo_1533 6dbb49a090eb0795446ccfeec8a3aab5 326 SUPERFAMILY SSF140931 60 252 2.75E-35 T 14-10-2018 IPR036597 Fido-like domain superfamily Tharo_1533 6dbb49a090eb0795446ccfeec8a3aab5 326 Gene3D G3DSA:1.10.3290.10 10 246 1.3E-39 T 14-10-2018 IPR036597 Fido-like domain superfamily Tharo_1384 c8ba8ce441d70c633520a4318e2e4804 423 Gene3D G3DSA:3.90.1150.10 289 423 8.3E-51 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_1384 c8ba8ce441d70c633520a4318e2e4804 423 Gene3D G3DSA:3.40.640.10 1 285 4.2E-104 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_1384 c8ba8ce441d70c633520a4318e2e4804 423 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 196 210 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Tharo_1384 c8ba8ce441d70c633520a4318e2e4804 423 PIRSF PIRSF001434 1 423 8.5E-132 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Tharo_1384 c8ba8ce441d70c633520a4318e2e4804 423 SUPERFAMILY SSF53383 1 421 1.46E-131 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_1384 c8ba8ce441d70c633520a4318e2e4804 423 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 420 5.7E-142 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Tharo_1384 c8ba8ce441d70c633520a4318e2e4804 423 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 2 421 3.3E-199 T 14-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 Tharo_0388 d19fdfe624fc2823a578541f1236ffb7 474 Pfam PF07196 Flagellin hook IN motif 124 183 3.1E-8 T 14-10-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 Tharo_0388 d19fdfe624fc2823a578541f1236ffb7 474 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 232 454 1.4E-49 T 14-10-2018 IPR010809 Flagellar hook-associated protein 2, C-terminal GO:0007155|GO:0009288 Tharo_0388 d19fdfe624fc2823a578541f1236ffb7 474 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 11 106 2.5E-22 T 14-10-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 Tharo_1287 3459256f891ba1ce9318fab26a2267dd 135 Gene3D G3DSA:3.10.129.10 1 130 1.0E-34 T 14-10-2018 Tharo_1287 3459256f891ba1ce9318fab26a2267dd 135 SUPERFAMILY SSF54637 4 131 1.37E-33 T 14-10-2018 IPR029069 HotDog domain superfamily Tharo_1287 3459256f891ba1ce9318fab26a2267dd 135 PIRSF PIRSF014972 2 134 1.5E-35 T 14-10-2018 IPR025540 Fluoroacetyl-CoA thioesterase Tharo_3331 8d09680bf7786dfbc15f73ead81e4028 195 Gene3D G3DSA:3.90.190.10 25 195 2.8E-28 T 14-10-2018 IPR029021 Protein-tyrosine phosphatase-like Tharo_3331 8d09680bf7786dfbc15f73ead81e4028 195 Pfam PF05706 Cyclin-dependent kinase inhibitor 3 (CDKN3) 68 166 1.5E-5 T 14-10-2018 IPR022778 CDKN3 domain GO:0004721|GO:0004725 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Tharo_3331 8d09680bf7786dfbc15f73ead81e4028 195 SUPERFAMILY SSF52799 58 192 3.67E-28 T 14-10-2018 IPR029021 Protein-tyrosine phosphatase-like Tharo_2951 eef23b8554ee1b1ae85a9f029a4da81c 167 Pfam PF13470 PIN domain 14 128 1.6E-22 T 14-10-2018 IPR002716 PIN domain Tharo_2951 eef23b8554ee1b1ae85a9f029a4da81c 167 SUPERFAMILY SSF88723 14 134 2.66E-11 T 14-10-2018 IPR029060 PIN-like domain superfamily Tharo_0714 4151f0f180fc449aa06e242ae2a9797d 479 Gene3D G3DSA:3.40.50.300 120 250 2.5E-5 T 14-10-2018 Tharo_0714 4151f0f180fc449aa06e242ae2a9797d 479 SUPERFAMILY SSF52540 158 248 4.33E-7 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0714 4151f0f180fc449aa06e242ae2a9797d 479 Pfam PF13175 AAA ATPase domain 160 228 3.7E-8 T 14-10-2018 Tharo_0283 0aac2ae4e38099d7e16936e216c0a01c 316 Pfam PF06834 TraU protein 35 304 4.8E-74 T 14-10-2018 IPR009649 TraU Tharo_0283 0aac2ae4e38099d7e16936e216c0a01c 316 TIGRFAM TIGR03756 conj_TIGR03756: integrating conjugative element protein, PFL_4710 family 30 314 2.5E-136 T 14-10-2018 IPR026331 Integrating conjugative element protein PFL_4710 Tharo_0296 81b168fe17e1b2c5fc83e0bacbc09d6a 432 Gene3D G3DSA:1.20.1250.20 12 407 2.3E-12 T 14-10-2018 Tharo_0296 81b168fe17e1b2c5fc83e0bacbc09d6a 432 SUPERFAMILY SSF103473 12 411 4.58E-18 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_0143 27e4eedb99db40aa675c5d7bbff6e07d 290 Gene3D G3DSA:3.30.470.10 2 123 3.8E-35 T 14-10-2018 Tharo_0143 27e4eedb99db40aa675c5d7bbff6e07d 290 Pfam PF01063 Amino-transferase class IV 33 255 2.7E-45 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 Tharo_0143 27e4eedb99db40aa675c5d7bbff6e07d 290 SUPERFAMILY SSF56752 5 281 2.22E-75 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 Tharo_0143 27e4eedb99db40aa675c5d7bbff6e07d 290 Gene3D G3DSA:3.20.10.10 125 287 1.5E-50 T 14-10-2018 Tharo_1778 890afc920a3060396f6da48f51221072 151 SUPERFAMILY SSF52833 4 151 9.42E-48 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_1778 890afc920a3060396f6da48f51221072 151 PIRSF PIRSF000239 3 151 9.4E-25 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Tharo_1778 890afc920a3060396f6da48f51221072 151 Pfam PF00578 AhpC/TSA family 5 129 3.5E-36 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Tharo_1778 890afc920a3060396f6da48f51221072 151 Gene3D G3DSA:3.40.30.10 2 150 3.0E-47 T 14-10-2018 Tharo_3299 81b4d29ec1c4880f8deb1b3d275492f9 210 Pfam PF03458 UPF0126 domain 17 86 1.0E-14 T 14-10-2018 IPR005115 Uncharacterised domain UPF0126 Tharo_3299 81b4d29ec1c4880f8deb1b3d275492f9 210 Pfam PF03458 UPF0126 domain 100 170 1.2E-20 T 14-10-2018 IPR005115 Uncharacterised domain UPF0126 Tharo_0517 77070af570cca8cffc874d511c1f144e 251 Gene3D G3DSA:2.60.440.10 4 249 2.8E-86 T 14-10-2018 IPR027462 Z ring-associated protein D, C-terminal Tharo_0517 77070af570cca8cffc874d511c1f144e 251 Hamap MF_01092 Cell division protein ZapD [zapD]. 1 249 33.988 T 14-10-2018 IPR009777 Cell division protein ZapD Tharo_0517 77070af570cca8cffc874d511c1f144e 251 Pfam PF07072 Cell division protein 16 225 8.9E-80 T 14-10-2018 IPR009777 Cell division protein ZapD Tharo_0517 77070af570cca8cffc874d511c1f144e 251 SUPERFAMILY SSF160950 2 249 1.44E-86 T 14-10-2018 IPR036268 ZapD domain superfamily Tharo_0517 77070af570cca8cffc874d511c1f144e 251 Gene3D G3DSA:1.10.3900.10 10 177 2.8E-86 T 14-10-2018 Tharo_2191 725f242b318f05eb2c3b32fd50cf0bd3 269 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 11 254 3.3E-86 T 14-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 Tharo_2191 725f242b318f05eb2c3b32fd50cf0bd3 269 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 9 261 42.8 T 14-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 Tharo_2191 725f242b318f05eb2c3b32fd50cf0bd3 269 Pfam PF02348 Cytidylyltransferase 13 231 3.9E-50 T 14-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 Tharo_2191 725f242b318f05eb2c3b32fd50cf0bd3 269 Gene3D G3DSA:3.90.550.10 10 261 3.9E-92 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_2191 725f242b318f05eb2c3b32fd50cf0bd3 269 SUPERFAMILY SSF53448 11 259 1.03E-58 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_3225 d72e76dbb834b0b3557b480ae559cb6a 348 Gene3D G3DSA:1.10.1610.10 19 344 2.7E-127 T 14-10-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 Tharo_3225 d72e76dbb834b0b3557b480ae559cb6a 348 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 9 344 1.5E-135 T 14-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 Tharo_3225 d72e76dbb834b0b3557b480ae559cb6a 348 Gene3D G3DSA:3.40.50.10210 51 327 2.7E-127 T 14-10-2018 Tharo_3225 d72e76dbb834b0b3557b480ae559cb6a 348 Pfam PF02277 Phosphoribosyltransferase 5 344 2.9E-130 T 14-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 Tharo_3225 d72e76dbb834b0b3557b480ae559cb6a 348 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 7 346 34.546 T 14-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 Tharo_3225 d72e76dbb834b0b3557b480ae559cb6a 348 SUPERFAMILY SSF52733 3 345 6.28E-116 T 14-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 Tharo_0419 c3e4a67a476298f370dcd1d968698e44 870 Pfam PF06048 Domain of unknown function (DUF927) 321 597 5.4E-99 T 14-10-2018 IPR009270 Domain of unknown function DUF927 Tharo_0419 c3e4a67a476298f370dcd1d968698e44 870 SUPERFAMILY SSF52540 505 704 3.22E-5 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0518 3f8da42b2e1b9ebd09213a25e09f338f 207 Pfam PF01121 Dephospho-CoA kinase 10 186 4.6E-60 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 Tharo_0518 3f8da42b2e1b9ebd09213a25e09f338f 207 Gene3D G3DSA:3.40.50.300 1 204 5.2E-67 T 14-10-2018 Tharo_0518 3f8da42b2e1b9ebd09213a25e09f338f 207 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 10 194 8.7E-48 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 Tharo_0518 3f8da42b2e1b9ebd09213a25e09f338f 207 SUPERFAMILY SSF52540 7 201 1.45E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0518 3f8da42b2e1b9ebd09213a25e09f338f 207 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 8 203 27.376 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 Tharo_0799 a1e64e1c00521eedb0d27b86e8a76cdc 404 TIGRFAM TIGR01937 nqrB: NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit 3 398 2.5E-183 T 14-10-2018 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0010181|GO:0016021|GO:0016655|GO:0022904 Tharo_0799 a1e64e1c00521eedb0d27b86e8a76cdc 404 PIRSF PIRSF016055 1 404 1.7E-198 T 14-10-2018 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0010181|GO:0016021|GO:0016655|GO:0022904 Tharo_0799 a1e64e1c00521eedb0d27b86e8a76cdc 404 Pfam PF03116 NQR2, RnfD, RnfE family 41 395 2.1E-110 T 14-10-2018 IPR004338 Ion-translocating oxidoreductase NqrB/RnfD GO:0016020|GO:0055085 Tharo_0799 a1e64e1c00521eedb0d27b86e8a76cdc 404 Hamap MF_00426 Na(+)-translocating NADH-quinone reductase subunit B [nqrB]. 2 402 37.119 T 14-10-2018 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0010181|GO:0016021|GO:0016655|GO:0022904 Tharo_2901 6b625623fae347a7c194a87d7930b2a1 118 Pfam PF07009 NusG domain II 13 108 1.1E-19 T 14-10-2018 IPR024045 NusG, domain 2 Tharo_2901 6b625623fae347a7c194a87d7930b2a1 118 Gene3D G3DSA:2.60.320.10 26 118 8.7E-20 T 14-10-2018 IPR038690 NusG, domain 2 superfamily Tharo_0805 d2f067f6c053878dedd7aa7bac60487c 126 Gene3D G3DSA:3.30.1330.40 3 126 9.3E-52 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 Tharo_0805 d2f067f6c053878dedd7aa7bac60487c 126 SUPERFAMILY SSF55298 2 125 2.36E-45 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 Tharo_0805 d2f067f6c053878dedd7aa7bac60487c 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 4 124 6.9E-50 T 14-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 Tharo_0805 d2f067f6c053878dedd7aa7bac60487c 126 Pfam PF01042 Endoribonuclease L-PSP 10 123 1.2E-39 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 Tharo_1231 9b6e1fff7f1653ecca3eb83098a3ed12 247 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 233 2.1E-70 T 14-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Tharo_1231 9b6e1fff7f1653ecca3eb83098a3ed12 247 SUPERFAMILY SSF64167 1 246 6.15E-87 T 14-10-2018 Tharo_1231 9b6e1fff7f1653ecca3eb83098a3ed12 247 Gene3D G3DSA:3.40.1210.10 1 247 3.2E-94 T 14-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Tharo_1231 9b6e1fff7f1653ecca3eb83098a3ed12 247 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 247 39.678 T 14-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Tharo_1231 9b6e1fff7f1653ecca3eb83098a3ed12 247 Pfam PF01975 Survival protein SurE 3 182 1.9E-61 T 14-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Tharo_2809 5810bf1c13051d3f967d13683045ef64 244 Pfam PF00005 ABC transporter 37 188 5.9E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_2809 5810bf1c13051d3f967d13683045ef64 244 Gene3D G3DSA:3.40.50.300 28 240 1.0E-47 T 14-10-2018 Tharo_2809 5810bf1c13051d3f967d13683045ef64 244 SMART SM00382 40 237 1.1E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2809 5810bf1c13051d3f967d13683045ef64 244 SUPERFAMILY SSF52540 12 233 1.43E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3022 da8539b7478c20784bcd1a7936f64b3c 210 Pfam PF01930 Domain of unknown function DUF83 9 188 1.7E-31 T 14-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 Tharo_3022 da8539b7478c20784bcd1a7936f64b3c 210 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 7 189 3.7E-41 T 14-10-2018 IPR013343 CRISPR-associated protein Cas4 Tharo_3022 da8539b7478c20784bcd1a7936f64b3c 210 Gene3D G3DSA:3.90.320.10 6 191 4.2E-14 T 14-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal Tharo_2414 b7d6fa896e73b2521664d637ed0672a0 112 Pfam PF13473 Cupredoxin-like domain 9 111 3.3E-21 T 14-10-2018 IPR028096 EfeO-type cupredoxin-like domain Tharo_2414 b7d6fa896e73b2521664d637ed0672a0 112 SUPERFAMILY SSF49503 10 110 7.46E-16 T 14-10-2018 IPR008972 Cupredoxin Tharo_2414 b7d6fa896e73b2521664d637ed0672a0 112 Gene3D G3DSA:2.60.40.420 16 112 4.9E-18 T 14-10-2018 IPR008972 Cupredoxin Tharo_1350 7e3ce88013c6015fe1dd95b0fbb4e5fd 154 Pfam PF17384 RimP C-terminal SH3 domain 89 154 1.1E-15 T 14-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal Tharo_1350 7e3ce88013c6015fe1dd95b0fbb4e5fd 154 Gene3D G3DSA:3.30.300.70 7 83 6.4E-15 T 14-10-2018 IPR035956 RimP, N-terminal domain superfamily Tharo_1350 7e3ce88013c6015fe1dd95b0fbb4e5fd 154 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 13 154 23.692 T 14-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 Tharo_1350 7e3ce88013c6015fe1dd95b0fbb4e5fd 154 Pfam PF02576 RimP N-terminal domain 18 86 3.7E-20 T 14-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal Tharo_1350 7e3ce88013c6015fe1dd95b0fbb4e5fd 154 SUPERFAMILY SSF75420 11 86 2.88E-18 T 14-10-2018 IPR035956 RimP, N-terminal domain superfamily Tharo_1350 7e3ce88013c6015fe1dd95b0fbb4e5fd 154 SUPERFAMILY SSF74942 87 154 7.59E-18 T 14-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily Tharo_1031 68738cdb8bf0e849ab405ed949df20b8 251 SUPERFAMILY SSF46626 27 215 1.82E-47 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_1031 68738cdb8bf0e849ab405ed949df20b8 251 Gene3D G3DSA:1.10.760.10 28 216 9.6E-16 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_1031 68738cdb8bf0e849ab405ed949df20b8 251 Pfam PF02167 Cytochrome C1 family 39 81 4.1E-5 T 14-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 Tharo_1031 68738cdb8bf0e849ab405ed949df20b8 251 Pfam PF02167 Cytochrome C1 family 108 249 2.3E-14 T 14-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 Tharo_3200 884aa7aa6ab367b631bbf1a9e8ee2c36 343 Gene3D G3DSA:1.10.443.10 115 294 3.1E-51 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Tharo_3200 884aa7aa6ab367b631bbf1a9e8ee2c36 343 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 13 300 53.617 T 14-10-2018 IPR023009 Tyrosine recombinase XerC/XerD Tharo_3200 884aa7aa6ab367b631bbf1a9e8ee2c36 343 Pfam PF00589 Phage integrase family 118 286 7.3E-39 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Tharo_3200 884aa7aa6ab367b631bbf1a9e8ee2c36 343 Gene3D G3DSA:1.10.150.130 11 103 1.6E-14 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Tharo_3200 884aa7aa6ab367b631bbf1a9e8ee2c36 343 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 15 94 4.5E-14 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 Tharo_3200 884aa7aa6ab367b631bbf1a9e8ee2c36 343 SUPERFAMILY SSF56349 14 293 4.71E-51 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Tharo_2675 76ac29b1989891ace879ccd7881a175c 303 SUPERFAMILY SSF53383 2 303 1.1E-82 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_2675 76ac29b1989891ace879ccd7881a175c 303 Gene3D G3DSA:3.40.640.10 2 201 1.0E-108 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_2675 76ac29b1989891ace879ccd7881a175c 303 Gene3D G3DSA:3.90.1150.10 202 300 1.0E-108 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_2675 76ac29b1989891ace879ccd7881a175c 303 Pfam PF00155 Aminotransferase class I and II 3 300 5.4E-52 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Tharo_0672 ee624779e663d520bef7b799f54636ce 473 Pfam PF01515 Phosphate acetyl/butaryl transferase 247 461 2.3E-42 T 14-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 Tharo_0672 ee624779e663d520bef7b799f54636ce 473 Pfam PF01575 MaoC like domain 34 121 6.4E-5 T 14-10-2018 IPR002539 MaoC-like dehydratase domain Tharo_0672 ee624779e663d520bef7b799f54636ce 473 SUPERFAMILY SSF53659 175 467 3.87E-68 T 14-10-2018 Tharo_0672 ee624779e663d520bef7b799f54636ce 473 Gene3D G3DSA:3.40.718.10 170 467 2.2E-96 T 14-10-2018 Tharo_0672 ee624779e663d520bef7b799f54636ce 473 Gene3D G3DSA:3.10.129.10 17 165 5.6E-25 T 14-10-2018 Tharo_0672 ee624779e663d520bef7b799f54636ce 473 SUPERFAMILY SSF54637 19 150 1.24E-20 T 14-10-2018 IPR029069 HotDog domain superfamily Tharo_1659 4bae068c4ab51875787a7abbd0aeaf35 144 Gene3D G3DSA:3.10.50.40 16 141 2.5E-35 T 14-10-2018 Tharo_1659 4bae068c4ab51875787a7abbd0aeaf35 144 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 7 81 1.4E-10 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain Tharo_1659 4bae068c4ab51875787a7abbd0aeaf35 144 Gene3D G3DSA:2.40.10.330 74 129 2.5E-35 T 14-10-2018 Tharo_1659 4bae068c4ab51875787a7abbd0aeaf35 144 SUPERFAMILY SSF54534 7 143 2.16E-31 T 14-10-2018 Tharo_0174 bb186a1ebdcbf4217216485b7f132573 356 Gene3D G3DSA:2.130.10.10 40 155 4.0E-7 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Tharo_0174 bb186a1ebdcbf4217216485b7f132573 356 SUPERFAMILY SSF110296 54 297 8.24E-39 T 14-10-2018 Tharo_0174 bb186a1ebdcbf4217216485b7f132573 356 Pfam PF14870 Photosynthesis system II assembly factor YCF48 160 280 1.4E-7 T 14-10-2018 IPR028203 Photosynthesis system II assembly factor Ycf48/Hcf136-like domain Tharo_0174 bb186a1ebdcbf4217216485b7f132573 356 Pfam PF14870 Photosynthesis system II assembly factor YCF48 79 126 1.7E-9 T 14-10-2018 IPR028203 Photosynthesis system II assembly factor Ycf48/Hcf136-like domain Tharo_0174 bb186a1ebdcbf4217216485b7f132573 356 Gene3D G3DSA:2.130.10.10 156 318 1.4E-11 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Tharo_0543 b122d2a81fc57edb15e0b74af369997c 731 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 650 661 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Tharo_0543 b122d2a81fc57edb15e0b74af369997c 731 PIRSF PIRSF036354 13 729 2.3E-167 T 14-10-2018 IPR011399 Nitrous oxide reductase expression regulator NosR GO:0003677|GO:0016020|GO:0045893 Tharo_0543 b122d2a81fc57edb15e0b74af369997c 731 SUPERFAMILY SSF54862 510 682 2.26E-9 T 14-10-2018 Tharo_0543 b122d2a81fc57edb15e0b74af369997c 731 SMART SM00900 103 197 1.1E-10 T 14-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 Tharo_0543 b122d2a81fc57edb15e0b74af369997c 731 Pfam PF12801 4Fe-4S binding domain 606 634 1.5E-4 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_0543 b122d2a81fc57edb15e0b74af369997c 731 Pfam PF12801 4Fe-4S binding domain 498 543 2.3E-14 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_0890 e4850655a367414bad62b1018af4e23d 96 SUPERFAMILY SSF81301 15 93 3.87E-15 T 14-10-2018 Tharo_0890 e4850655a367414bad62b1018af4e23d 96 Gene3D G3DSA:3.30.460.10 4 96 3.4E-21 T 14-10-2018 Tharo_0890 e4850655a367414bad62b1018af4e23d 96 Pfam PF01909 Nucleotidyltransferase domain 12 45 4.9E-8 T 14-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Tharo_2523 6cc733012bea7eddf44fdb2858a49f66 162 Pfam PF01967 MoaC family 20 155 1.4E-53 T 14-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Tharo_2523 6cc733012bea7eddf44fdb2858a49f66 162 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 7 162 34.497 T 14-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Tharo_2523 6cc733012bea7eddf44fdb2858a49f66 162 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 9 157 7.7E-62 T 14-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Tharo_2523 6cc733012bea7eddf44fdb2858a49f66 162 SUPERFAMILY SSF55040 16 160 1.96E-60 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Tharo_2523 6cc733012bea7eddf44fdb2858a49f66 162 Gene3D G3DSA:3.30.70.640 7 162 1.5E-67 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Tharo_2212 11e340af10b87e770a6d5d3484006d3f 296 Gene3D G3DSA:1.10.340.30 120 241 9.2E-44 T 14-10-2018 Tharo_2212 11e340af10b87e770a6d5d3484006d3f 296 SMART SM01009 6 122 3.2E-10 T 14-10-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal Tharo_2212 11e340af10b87e770a6d5d3484006d3f 296 SUPERFAMILY SSF48150 113 291 1.33E-35 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 Tharo_2212 11e340af10b87e770a6d5d3484006d3f 296 Gene3D G3DSA:1.10.1670.40 100 291 9.2E-44 T 14-10-2018 Tharo_2212 11e340af10b87e770a6d5d3484006d3f 296 SMART SM00478 132 294 1.7E-7 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Tharo_2212 11e340af10b87e770a6d5d3484006d3f 296 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 130 272 1.8E-6 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Tharo_2358 58b5daf0917fb49def5b7811cc7f9db7 150 Pfam PF00293 NUDIX domain 8 126 1.5E-14 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Tharo_2358 58b5daf0917fb49def5b7811cc7f9db7 150 Gene3D G3DSA:3.90.79.10 3 150 3.1E-41 T 14-10-2018 Tharo_2358 58b5daf0917fb49def5b7811cc7f9db7 150 SUPERFAMILY SSF55811 7 148 8.53E-27 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Tharo_3206 80be46b80ba85f2afd3a6ce1f41ed63e 357 Pfam PF01699 Sodium/calcium exchanger protein 175 315 7.1E-31 T 14-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 Tharo_3206 80be46b80ba85f2afd3a6ce1f41ed63e 357 Pfam PF01699 Sodium/calcium exchanger protein 5 144 1.8E-29 T 14-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 Tharo_3206 80be46b80ba85f2afd3a6ce1f41ed63e 357 Gene3D G3DSA:1.20.58.1130 8 206 9.5E-92 T 14-10-2018 Tharo_3206 80be46b80ba85f2afd3a6ce1f41ed63e 357 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 2 312 9.7E-83 T 14-10-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 Tharo_3206 80be46b80ba85f2afd3a6ce1f41ed63e 357 Gene3D G3DSA:1.20.1420.30 35 309 9.5E-92 T 14-10-2018 Tharo_2749 91a9e7fbccebc2ac449e4383d71d14a0 313 Pfam PF00482 Type II secretion system (T2SS), protein F 166 294 1.8E-19 T 14-10-2018 IPR018076 Type II secretion system F domain Tharo_3254 ed32d27de7e7036ea2e9399d4c0757b1 298 Gene3D G3DSA:1.20.1510.10 6 203 1.7E-57 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Tharo_3254 ed32d27de7e7036ea2e9399d4c0757b1 298 Pfam PF16916 Dimerisation domain of Zinc Transporter 209 284 3.2E-11 T 14-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain Tharo_3254 ed32d27de7e7036ea2e9399d4c0757b1 298 Pfam PF01545 Cation efflux family 10 204 2.4E-36 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Tharo_3254 ed32d27de7e7036ea2e9399d4c0757b1 298 SUPERFAMILY SSF161111 7 205 1.05E-51 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Tharo_3254 ed32d27de7e7036ea2e9399d4c0757b1 298 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 8 284 6.8E-59 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Tharo_3254 ed32d27de7e7036ea2e9399d4c0757b1 298 Gene3D G3DSA:3.30.70.1350 204 290 6.8E-15 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 Tharo_3254 ed32d27de7e7036ea2e9399d4c0757b1 298 SUPERFAMILY SSF160240 209 285 7.19E-10 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 Tharo_1511 ccc758241d7fc47eece7322de240788b 264 SUPERFAMILY SSF46689 212 258 1.16E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_1511 ccc758241d7fc47eece7322de240788b 264 SMART SM00342 174 256 7.8E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Tharo_1511 ccc758241d7fc47eece7322de240788b 264 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 211 252 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Tharo_1511 ccc758241d7fc47eece7322de240788b 264 SUPERFAMILY SSF51182 12 187 2.96E-13 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily Tharo_1511 ccc758241d7fc47eece7322de240788b 264 Pfam PF12833 Helix-turn-helix domain 180 257 2.2E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Tharo_1511 ccc758241d7fc47eece7322de240788b 264 Gene3D G3DSA:1.10.10.60 157 261 1.4E-18 T 14-10-2018 Tharo_2902 6e702ce7027ca5d8f5c567e52cfc96c1 299 Pfam PF03668 P-loop ATPase protein family 1 277 1.0E-92 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 Tharo_2902 6e702ce7027ca5d8f5c567e52cfc96c1 299 Gene3D G3DSA:3.40.50.300 1 157 1.8E-5 T 14-10-2018 Tharo_2902 6e702ce7027ca5d8f5c567e52cfc96c1 299 PIRSF PIRSF005052 1 283 1.5E-104 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 Tharo_2902 6e702ce7027ca5d8f5c567e52cfc96c1 299 SUPERFAMILY SSF52540 1 153 1.29E-9 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2902 6e702ce7027ca5d8f5c567e52cfc96c1 299 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 280 39.48 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 Tharo_0400 326a5ea88a5f0e441ed5ee0d9420cff9 314 PRINTS PR00996 Glutamate methyltransferase family signature 122 142 1.0E-44 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_0400 326a5ea88a5f0e441ed5ee0d9420cff9 314 PRINTS PR00996 Glutamate methyltransferase family signature 89 101 1.0E-44 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_0400 326a5ea88a5f0e441ed5ee0d9420cff9 314 PRINTS PR00996 Glutamate methyltransferase family signature 247 270 1.0E-44 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_0400 326a5ea88a5f0e441ed5ee0d9420cff9 314 PRINTS PR00996 Glutamate methyltransferase family signature 50 63 1.0E-44 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_0400 326a5ea88a5f0e441ed5ee0d9420cff9 314 PRINTS PR00996 Glutamate methyltransferase family signature 156 172 1.0E-44 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_0400 326a5ea88a5f0e441ed5ee0d9420cff9 314 PRINTS PR00996 Glutamate methyltransferase family signature 228 242 1.0E-44 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_0400 326a5ea88a5f0e441ed5ee0d9420cff9 314 PIRSF PIRSF000410 12 289 6.2E-97 T 14-10-2018 IPR026024 Chemotaxis protein methyltransferase CheR Tharo_0400 326a5ea88a5f0e441ed5ee0d9420cff9 314 Gene3D G3DSA:3.40.50.150 95 288 2.2E-69 T 14-10-2018 Tharo_0400 326a5ea88a5f0e441ed5ee0d9420cff9 314 Pfam PF03705 CheR methyltransferase, all-alpha domain 30 80 2.7E-19 T 14-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal Tharo_0400 326a5ea88a5f0e441ed5ee0d9420cff9 314 SUPERFAMILY SSF47757 21 95 7.98E-23 T 14-10-2018 Tharo_0400 326a5ea88a5f0e441ed5ee0d9420cff9 314 SUPERFAMILY SSF53335 96 285 8.53E-58 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_0400 326a5ea88a5f0e441ed5ee0d9420cff9 314 Pfam PF01739 CheR methyltransferase, SAM binding domain 96 285 1.2E-59 T 14-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal Tharo_0400 326a5ea88a5f0e441ed5ee0d9420cff9 314 SMART SM00138 28 288 1.7E-105 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Tharo_0400 326a5ea88a5f0e441ed5ee0d9420cff9 314 Gene3D G3DSA:1.10.155.10 18 94 6.9E-28 T 14-10-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily Tharo_2281 6e522932b184d9b15c72a55916c45ea2 70 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 Tharo_2281 6e522932b184d9b15c72a55916c45ea2 70 Pfam PF00403 Heavy-metal-associated domain 5 66 8.2E-19 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 Tharo_2281 6e522932b184d9b15c72a55916c45ea2 70 Gene3D G3DSA:3.30.70.100 1 67 5.5E-24 T 14-10-2018 Tharo_2281 6e522932b184d9b15c72a55916c45ea2 70 SUPERFAMILY SSF55008 2 66 3.4E-21 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 Tharo_2078 20314c25159fbd25aaa40febfe6d591d 392 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 4 342 1.4E-124 T 14-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 Tharo_2078 20314c25159fbd25aaa40febfe6d591d 392 Pfam PF00437 Type II/IV secretion system protein 8 270 3.0E-40 T 14-10-2018 IPR001482 Type II/IV secretion system protein Tharo_2078 20314c25159fbd25aaa40febfe6d591d 392 Gene3D G3DSA:3.30.450.90 2 100 2.5E-24 T 14-10-2018 Tharo_2078 20314c25159fbd25aaa40febfe6d591d 392 Gene3D G3DSA:3.40.50.300 101 356 2.2E-89 T 14-10-2018 Tharo_2078 20314c25159fbd25aaa40febfe6d591d 392 SUPERFAMILY SSF52540 3 335 2.0E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2078 20314c25159fbd25aaa40febfe6d591d 392 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 14-10-2018 IPR001482 Type II/IV secretion system protein Tharo_1176 db5f266babc3af7532f053f27acd9b84 105 Gene3D G3DSA:3.30.70.260 10 105 4.0E-33 T 14-10-2018 Tharo_1176 db5f266babc3af7532f053f27acd9b84 105 SUPERFAMILY SSF55021 17 90 2.11E-16 T 14-10-2018 Tharo_1176 db5f266babc3af7532f053f27acd9b84 105 Pfam PF01842 ACT domain 19 82 7.8E-11 T 14-10-2018 IPR002912 ACT domain Tharo_1176 db5f266babc3af7532f053f27acd9b84 105 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 24 87 3.0E-16 T 14-10-2018 Tharo_3220 1643c0d2b0164d96cc6dbe442b624db2 338 SUPERFAMILY SSF81345 17 335 1.57E-73 T 14-10-2018 IPR037294 ABC transporter, BtuC-like Tharo_3220 1643c0d2b0164d96cc6dbe442b624db2 338 Gene3D G3DSA:1.10.3470.10 16 338 1.8E-93 T 14-10-2018 IPR037294 ABC transporter, BtuC-like Tharo_3220 1643c0d2b0164d96cc6dbe442b624db2 338 Pfam PF01032 FecCD transport family 31 335 5.6E-87 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 Tharo_0470 c67b7bd1e9ca3475ddf3a4e102b7ebdc 338 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 131 331 8.7E-53 T 14-10-2018 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 Tharo_0470 c67b7bd1e9ca3475ddf3a4e102b7ebdc 338 Gene3D G3DSA:1.20.950.20 126 337 3.2E-63 T 14-10-2018 Tharo_0470 c67b7bd1e9ca3475ddf3a4e102b7ebdc 338 SUPERFAMILY SSF81342 127 334 1.88E-41 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 Tharo_0470 c67b7bd1e9ca3475ddf3a4e102b7ebdc 338 Pfam PF01292 Prokaryotic cytochrome b561 133 312 1.1E-19 T 14-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 Tharo_1553 e3e077531777ce2219ecc5f449f18c13 135 Pfam PF01337 Barstar (barnase inhibitor) 25 107 2.3E-26 T 14-10-2018 IPR000468 Barstar (barnase inhibitor) Tharo_1553 e3e077531777ce2219ecc5f449f18c13 135 SUPERFAMILY SSF52038 24 111 1.96E-23 T 14-10-2018 IPR035905 Barstar-like superfamily Tharo_1553 e3e077531777ce2219ecc5f449f18c13 135 Gene3D G3DSA:3.30.370.10 22 113 5.3E-13 T 14-10-2018 IPR035905 Barstar-like superfamily Tharo_1837 abb0644329e4d2bc5829e3de126b57f2 677 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 18 670 1.0E-216 T 14-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ Tharo_1837 abb0644329e4d2bc5829e3de126b57f2 677 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 113 594 2.5E-83 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit Tharo_1032 7713513624bcee55b4106dc126127ee8 198 Gene3D G3DSA:3.40.30.10 2 190 5.8E-74 T 14-10-2018 Tharo_1032 7713513624bcee55b4106dc126127ee8 198 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 72 9.6E-17 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 Tharo_1032 7713513624bcee55b4106dc126127ee8 198 Pfam PF00043 Glutathione S-transferase, C-terminal domain 106 182 2.5E-8 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal Tharo_1032 7713513624bcee55b4106dc126127ee8 198 SUPERFAMILY SSF52833 1 101 5.91E-25 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_1032 7713513624bcee55b4106dc126127ee8 198 SUPERFAMILY SSF47616 73 197 9.81E-26 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily Tharo_1032 7713513624bcee55b4106dc126127ee8 198 Gene3D G3DSA:1.20.1050.10 80 182 5.8E-74 T 14-10-2018 Tharo_1753 a2fff63112a6be3ed8f5e5f2edba532b 547 Gene3D G3DSA:1.10.760.10 19 124 6.4E-20 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_1753 a2fff63112a6be3ed8f5e5f2edba532b 547 SUPERFAMILY SSF51004 130 540 1.03E-71 T 14-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily Tharo_1753 a2fff63112a6be3ed8f5e5f2edba532b 547 SUPERFAMILY SSF46626 6 130 1.17E-21 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_1753 a2fff63112a6be3ed8f5e5f2edba532b 547 Pfam PF02239 Cytochrome D1 heme domain 157 538 2.4E-97 T 14-10-2018 Tharo_1753 a2fff63112a6be3ed8f5e5f2edba532b 547 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 47 120 5.2E-13 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_1753 a2fff63112a6be3ed8f5e5f2edba532b 547 Gene3D G3DSA:2.140.10.20 128 541 5.5E-104 T 14-10-2018 IPR003143 Cytochrome cd1-nitrite reductase, C-terminal domain superfamily Tharo_2412 24f54f38e66466efbb62940166125d44 469 Pfam PF12801 4Fe-4S binding domain 78 114 9.5E-8 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_2412 24f54f38e66466efbb62940166125d44 469 Pfam PF12801 4Fe-4S binding domain 163 195 2.3E-4 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Tharo_2384 bdcce3c13307d38e14685d5a7c7899be 355 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 2 93 1.1E-18 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain Tharo_2384 bdcce3c13307d38e14685d5a7c7899be 355 Gene3D G3DSA:3.40.140.10 1 129 5.4E-44 T 14-10-2018 Tharo_2384 bdcce3c13307d38e14685d5a7c7899be 355 PIRSF PIRSF006769 1 353 5.7E-122 T 14-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 Tharo_2384 bdcce3c13307d38e14685d5a7c7899be 355 Pfam PF01872 RibD C-terminal domain 141 345 4.3E-44 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 Tharo_2384 bdcce3c13307d38e14685d5a7c7899be 355 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 1 347 3.4E-117 T 14-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 Tharo_2384 bdcce3c13307d38e14685d5a7c7899be 355 Gene3D G3DSA:3.40.430.10 130 352 2.7E-66 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 Tharo_2384 bdcce3c13307d38e14685d5a7c7899be 355 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 140 350 9.8E-55 T 14-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 Tharo_2384 bdcce3c13307d38e14685d5a7c7899be 355 SUPERFAMILY SSF53597 139 349 4.14E-55 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 Tharo_2384 bdcce3c13307d38e14685d5a7c7899be 355 SUPERFAMILY SSF53927 1 138 4.33E-46 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Tharo_2384 bdcce3c13307d38e14685d5a7c7899be 355 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 44 82 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 Tharo_2076 d359ed5f6c59c1ea80aa067d32b5f772 397 Gene3D G3DSA:3.90.1150.10 13 382 1.2E-108 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Tharo_2076 d359ed5f6c59c1ea80aa067d32b5f772 397 SUPERFAMILY SSF53383 2 395 5.5E-85 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Tharo_2076 d359ed5f6c59c1ea80aa067d32b5f772 397 Pfam PF00155 Aminotransferase class I and II 32 390 3.4E-46 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Tharo_2076 d359ed5f6c59c1ea80aa067d32b5f772 397 Gene3D G3DSA:3.40.640.10 43 291 1.2E-108 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Tharo_2076 d359ed5f6c59c1ea80aa067d32b5f772 397 TIGRFAM TIGR03538 DapC_gpp: succinyldiaminopimelate transaminase 1 394 2.6E-188 T 14-10-2018 IPR019878 Succinyldiaminopimelate transaminase, DapC, beta/gammaproteobacteria GO:0009016|GO:0009089 Tharo_0676 05c29a2e60f2a13387891517d01d8a7e 376 Pfam PF12698 ABC-2 family transporter protein 28 365 3.8E-35 T 14-10-2018 Tharo_2872 b48a1d3d7c0fb8c8dbf215f61350e588 445 SUPERFAMILY SSF52540 3 440 3.8E-83 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2872 b48a1d3d7c0fb8c8dbf215f61350e588 445 Pfam PF07724 AAA domain (Cdc48 subfamily) 189 330 5.8E-40 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Tharo_2872 b48a1d3d7c0fb8c8dbf215f61350e588 445 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 1 445 41.805 T 14-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 Tharo_2872 b48a1d3d7c0fb8c8dbf215f61350e588 445 SMART SM00382 49 333 1.5E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2872 b48a1d3d7c0fb8c8dbf215f61350e588 445 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 53 99 4.3E-6 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Tharo_2872 b48a1d3d7c0fb8c8dbf215f61350e588 445 SMART SM01086 336 433 9.3E-17 T 14-10-2018 IPR019489 Clp ATPase, C-terminal Tharo_2872 b48a1d3d7c0fb8c8dbf215f61350e588 445 Gene3D G3DSA:1.10.8.60 336 442 2.1E-34 T 14-10-2018 Tharo_2872 b48a1d3d7c0fb8c8dbf215f61350e588 445 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 4 445 7.9E-201 T 14-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 Tharo_2955 f6a16ae69ab6d38a4f177ee9c875300b 201 SUPERFAMILY SSF110997 125 196 4.45E-16 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 Tharo_2955 f6a16ae69ab6d38a4f177ee9c875300b 201 Gene3D G3DSA:3.30.70.1070 119 200 1.4E-13 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 Tharo_2955 f6a16ae69ab6d38a4f177ee9c875300b 201 Pfam PF05036 Sporulation related domain 126 196 1.2E-14 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 Tharo_0639 bd2c1396fd56d7ef1dedfcf3103cd43f 249 Pfam PF00977 Histidine biosynthesis protein 3 232 8.9E-78 T 14-10-2018 IPR006062 Histidine biosynthesis GO:0000105 Tharo_0639 bd2c1396fd56d7ef1dedfcf3103cd43f 249 Gene3D G3DSA:3.20.20.70 1 242 6.4E-85 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_0639 bd2c1396fd56d7ef1dedfcf3103cd43f 249 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 240 35.63 T 14-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 Tharo_0639 bd2c1396fd56d7ef1dedfcf3103cd43f 249 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 235 4.0E-76 T 14-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 Tharo_0639 bd2c1396fd56d7ef1dedfcf3103cd43f 249 SUPERFAMILY SSF51366 1 238 2.67E-73 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Tharo_1734 fcbe5b49bf38690763e8ead5b18d4c00 190 Pfam PF06930 Protein of unknown function (DUF1282) 11 177 3.0E-16 T 14-10-2018 IPR009698 Protein of unknown function DUF1282 Tharo_1118 da89108c51e0b6eac209462b877ef641 381 Gene3D G3DSA:3.40.50.2300 28 364 2.2E-112 T 14-10-2018 Tharo_1118 da89108c51e0b6eac209462b877ef641 381 SUPERFAMILY SSF53822 25 380 2.59E-69 T 14-10-2018 IPR028082 Periplasmic binding protein-like I Tharo_1118 da89108c51e0b6eac209462b877ef641 381 Gene3D G3DSA:3.40.50.2300 137 374 2.2E-112 T 14-10-2018 Tharo_1118 da89108c51e0b6eac209462b877ef641 381 Pfam PF13458 Periplasmic binding protein 26 360 3.1E-50 T 14-10-2018 IPR028081 Leucine-binding protein domain Tharo_1082 655414000d68fed4f4988538519fa7e2 253 Pfam PF11306 Protein of unknown function (DUF3108) 23 227 4.5E-28 T 14-10-2018 IPR021457 Protein of unknown function DUF3108 Tharo_2463 e51fc5c8e93746c50706dd896a5d9521 461 Gene3D G3DSA:1.10.287.470 236 311 5.1E-16 T 14-10-2018 Tharo_2463 e51fc5c8e93746c50706dd896a5d9521 461 Gene3D G3DSA:2.40.50.100 312 348 5.1E-16 T 14-10-2018 Tharo_2463 e51fc5c8e93746c50706dd896a5d9521 461 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 48 461 2.8E-108 T 14-10-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 Tharo_2463 e51fc5c8e93746c50706dd896a5d9521 461 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 56 79 2.6E-40 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_2463 e51fc5c8e93746c50706dd896a5d9521 461 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 425 440 2.6E-40 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_2463 e51fc5c8e93746c50706dd896a5d9521 461 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 98 118 2.6E-40 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_2463 e51fc5c8e93746c50706dd896a5d9521 461 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 324 345 2.6E-40 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_2463 e51fc5c8e93746c50706dd896a5d9521 461 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 381 404 2.6E-40 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_2463 e51fc5c8e93746c50706dd896a5d9521 461 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 440 460 2.6E-40 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_2463 e51fc5c8e93746c50706dd896a5d9521 461 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 357 381 2.6E-40 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Tharo_2463 e51fc5c8e93746c50706dd896a5d9521 461 Gene3D G3DSA:2.40.30.170 349 438 5.1E-16 T 14-10-2018 Tharo_2463 e51fc5c8e93746c50706dd896a5d9521 461 Gene3D G3DSA:2.40.50.100 95 148 4.7E-5 T 14-10-2018 Tharo_2463 e51fc5c8e93746c50706dd896a5d9521 461 Pfam PF13437 HlyD family secretion protein 311 414 2.2E-16 T 14-10-2018 Tharo_2463 e51fc5c8e93746c50706dd896a5d9521 461 SUPERFAMILY SSF111369 77 165 5.75E-5 T 14-10-2018 Tharo_2463 e51fc5c8e93746c50706dd896a5d9521 461 Pfam PF13533 Biotin-lipoyl like 93 134 4.1E-5 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain Tharo_2379 d8efa0ac41a93cbb9adbba9dc4c06c90 349 Gene3D G3DSA:3.40.190.10 141 312 1.1E-125 T 14-10-2018 Tharo_2379 d8efa0ac41a93cbb9adbba9dc4c06c90 349 PIRSF PIRSF039026 1 346 6.2E-119 T 14-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like Tharo_2379 d8efa0ac41a93cbb9adbba9dc4c06c90 349 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 27 307 5.0E-61 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 Tharo_2379 d8efa0ac41a93cbb9adbba9dc4c06c90 349 SUPERFAMILY SSF53850 134 251 5.79E-6 T 14-10-2018 Tharo_2379 d8efa0ac41a93cbb9adbba9dc4c06c90 349 Gene3D G3DSA:3.40.190.170 21 325 1.1E-125 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily Tharo_0247 58fa7dd7cb6e57e231462a53335b9ab3 159 Gene3D G3DSA:1.20.120.520 2 151 3.9E-20 T 14-10-2018 Tharo_0247 58fa7dd7cb6e57e231462a53335b9ab3 159 Pfam PF01814 Hemerythrin HHE cation binding domain 5 128 3.0E-10 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 Tharo_0922 237adaa8f86a21b3b34e7bdecd2c4a30 465 SUPERFAMILY SSF51984 5 96 3.14E-16 T 14-10-2018 Tharo_0922 237adaa8f86a21b3b34e7bdecd2c4a30 465 Gene3D G3DSA:3.40.50.720 4 95 2.7E-22 T 14-10-2018 Tharo_0922 237adaa8f86a21b3b34e7bdecd2c4a30 465 Gene3D G3DSA:3.40.1190.10 103 319 2.9E-56 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Tharo_0922 237adaa8f86a21b3b34e7bdecd2c4a30 465 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 7 459 32.507 T 14-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Tharo_0922 237adaa8f86a21b3b34e7bdecd2c4a30 465 SUPERFAMILY SSF53623 114 317 4.58E-47 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Tharo_0922 237adaa8f86a21b3b34e7bdecd2c4a30 465 Pfam PF08245 Mur ligase middle domain 120 299 9.2E-31 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Tharo_0922 237adaa8f86a21b3b34e7bdecd2c4a30 465 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 8 457 1.8E-113 T 14-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Tharo_0922 237adaa8f86a21b3b34e7bdecd2c4a30 465 Gene3D G3DSA:3.90.190.20 320 455 2.0E-40 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Tharo_0922 237adaa8f86a21b3b34e7bdecd2c4a30 465 SUPERFAMILY SSF53244 319 459 2.38E-41 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Tharo_2411 d3798bb04d91668244c10d1b3f98f9bc 291 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 215 1.1E-71 T 14-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 Tharo_2411 d3798bb04d91668244c10d1b3f98f9bc 291 SUPERFAMILY SSF52540 4 287 5.32E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2411 d3798bb04d91668244c10d1b3f98f9bc 291 PRINTS PR00478 Phosphoribulokinase family signature 165 182 8.4E-31 T 14-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 Tharo_2411 d3798bb04d91668244c10d1b3f98f9bc 291 PRINTS PR00478 Phosphoribulokinase family signature 12 29 8.4E-31 T 14-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 Tharo_2411 d3798bb04d91668244c10d1b3f98f9bc 291 PRINTS PR00478 Phosphoribulokinase family signature 127 145 8.4E-31 T 14-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 Tharo_2411 d3798bb04d91668244c10d1b3f98f9bc 291 PRINTS PR00478 Phosphoribulokinase family signature 183 206 8.4E-31 T 14-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 Tharo_2411 d3798bb04d91668244c10d1b3f98f9bc 291 Gene3D G3DSA:3.40.50.300 1 290 2.3E-115 T 14-10-2018 Tharo_2411 d3798bb04d91668244c10d1b3f98f9bc 291 ProSitePatterns PS00567 Phosphoribulokinase signature. 165 178 - T 14-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 Tharo_1173 3c8bbc4716c5b52443c839d57fb74dec 141 SMART SM00116 66 113 7.2E-5 T 14-10-2018 IPR000644 CBS domain Tharo_1173 3c8bbc4716c5b52443c839d57fb74dec 141 SMART SM00116 1 48 0.0059 T 14-10-2018 IPR000644 CBS domain Tharo_1173 3c8bbc4716c5b52443c839d57fb74dec 141 Gene3D G3DSA:3.10.580.10 1 135 3.1E-33 T 14-10-2018 Tharo_1173 3c8bbc4716c5b52443c839d57fb74dec 141 SUPERFAMILY SSF54631 3 130 9.22E-29 T 14-10-2018 Tharo_1173 3c8bbc4716c5b52443c839d57fb74dec 141 Pfam PF00571 CBS domain 59 113 8.1E-10 T 14-10-2018 IPR000644 CBS domain Tharo_1173 3c8bbc4716c5b52443c839d57fb74dec 141 Pfam PF00571 CBS domain 3 47 2.3E-5 T 14-10-2018 IPR000644 CBS domain Tharo_2439 24f1e686f21d3ecb07fd0a0e67469edf 420 SUPERFAMILY SSF103473 6 409 1.57E-64 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_2439 24f1e686f21d3ecb07fd0a0e67469edf 420 Pfam PF07690 Major Facilitator Superfamily 16 357 1.4E-39 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_2439 24f1e686f21d3ecb07fd0a0e67469edf 420 ProSitePatterns PS00216 Sugar transport proteins signature 1. 271 288 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Tharo_2439 24f1e686f21d3ecb07fd0a0e67469edf 420 Gene3D G3DSA:1.20.1250.20 207 411 1.3E-26 T 14-10-2018 Tharo_2439 24f1e686f21d3ecb07fd0a0e67469edf 420 Gene3D G3DSA:1.20.1250.20 3 193 4.4E-32 T 14-10-2018 Tharo_0685 6fc771d5c56b22035c582eea501501f9 125 Pfam PF13521 AAA domain 3 114 1.3E-19 T 14-10-2018 IPR038727 NadR/Ttd14, AAA domain Tharo_1736 f023c4d5ac3eaab3b2fbc7a251e97a6f 145 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 134 2.7E-25 T 14-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 Tharo_1736 f023c4d5ac3eaab3b2fbc7a251e97a6f 145 Gene3D G3DSA:3.30.530.20 3 144 3.0E-30 T 14-10-2018 IPR023393 START-like domain superfamily Tharo_1736 f023c4d5ac3eaab3b2fbc7a251e97a6f 145 SUPERFAMILY SSF55961 1 143 3.76E-28 T 14-10-2018 Tharo_0424 8e9f0cfda233aa2e0075391a78c14ef3 285 Pfam PF04383 KilA-N domain 15 126 2.9E-23 T 14-10-2018 IPR018004 KilA, N-terminal/APSES-type HTH, DNA-binding Tharo_0424 8e9f0cfda233aa2e0075391a78c14ef3 285 SMART SM01252 18 127 2.5E-21 T 14-10-2018 IPR018004 KilA, N-terminal/APSES-type HTH, DNA-binding Tharo_0424 8e9f0cfda233aa2e0075391a78c14ef3 285 SUPERFAMILY SSF54616 10 128 2.09E-13 T 14-10-2018 IPR036887 HTH APSES-type DNA-binding domain superfamily GO:0003677 Tharo_1960 ee6effb0a2e577bffee854c4f14f9ba5 372 Pfam PF02405 Permease MlaE 155 363 3.4E-64 T 14-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 Tharo_1960 ee6effb0a2e577bffee854c4f14f9ba5 372 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 128 363 1.8E-64 T 14-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria Tharo_0137 4c060a6ac4baaee75dc53edd44cf196f 271 Gene3D G3DSA:2.40.10.340 109 254 6.1E-31 T 14-10-2018 Tharo_0137 4c060a6ac4baaee75dc53edd44cf196f 271 Pfam PF04085 rod shape-determining protein MreC 112 255 1.3E-35 T 14-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 Tharo_0137 4c060a6ac4baaee75dc53edd44cf196f 271 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 1 257 1.3E-48 T 14-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 Tharo_0137 4c060a6ac4baaee75dc53edd44cf196f 271 PIRSF PIRSF038471 1 270 1.7E-68 T 14-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 Tharo_0137 4c060a6ac4baaee75dc53edd44cf196f 271 Gene3D G3DSA:2.40.10.350 168 243 6.1E-31 T 14-10-2018 Tharo_0985 7ef4833f58fee986a67956592bf69751 427 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 421 1.3E-161 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 Tharo_0985 7ef4833f58fee986a67956592bf69751 427 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 416 2.0E-134 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit Tharo_0985 7ef4833f58fee986a67956592bf69751 427 PIRSF PIRSF006066 1 427 1.8E-157 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 Tharo_1061 0dc11a12dce78b1ec89df417ce893257 283 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 141 158 3.6E-29 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial Tharo_1061 0dc11a12dce78b1ec89df417ce893257 283 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 209 220 3.6E-29 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial Tharo_1061 0dc11a12dce78b1ec89df417ce893257 283 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 198 208 3.6E-29 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial Tharo_1061 0dc11a12dce78b1ec89df417ce893257 283 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 221 236 3.6E-29 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial Tharo_1061 0dc11a12dce78b1ec89df417ce893257 283 Pfam PF01478 Type IV leader peptidase family 134 241 2.4E-27 T 14-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 Tharo_1061 0dc11a12dce78b1ec89df417ce893257 283 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 17 122 6.4E-35 T 14-10-2018 IPR010627 Peptidase A24A, N-terminal Tharo_3052 47d16b081096d4fc7eb1a6b46a7d59fc 206 Gene3D G3DSA:2.60.40.1190 51 197 5.4E-9 T 14-10-2018 Tharo_0732 ceb039c65502ac5f0601eb9e4f7d225b 535 Gene3D G3DSA:3.40.50.150 10 218 2.1E-40 T 14-10-2018 Tharo_0732 ceb039c65502ac5f0601eb9e4f7d225b 535 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 83 95 - T 14-10-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-4655427|Reactome: R-HSA-5334118 Tharo_0732 ceb039c65502ac5f0601eb9e4f7d225b 535 Pfam PF00145 C-5 cytosine-specific DNA methylase 468 521 1.7E-6 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 Tharo_0732 ceb039c65502ac5f0601eb9e4f7d225b 535 Pfam PF00145 C-5 cytosine-specific DNA methylase 21 210 5.5E-29 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 Tharo_0732 ceb039c65502ac5f0601eb9e4f7d225b 535 SUPERFAMILY SSF53335 19 526 6.64E-55 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_0732 ceb039c65502ac5f0601eb9e4f7d225b 535 Gene3D G3DSA:3.90.120.10 463 513 2.7E-5 T 14-10-2018 Tharo_0454 17b80c0406d1a0cca558f86aa879c6b9 102 Pfam PF00034 Cytochrome c 23 102 4.6E-9 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0454 17b80c0406d1a0cca558f86aa879c6b9 102 SUPERFAMILY SSF46626 28 101 1.63E-18 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_0454 17b80c0406d1a0cca558f86aa879c6b9 102 PRINTS PR00606 Class ID cytochrome C signature 78 88 4.5E-25 T 14-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 Tharo_0454 17b80c0406d1a0cca558f86aa879c6b9 102 PRINTS PR00606 Class ID cytochrome C signature 90 100 4.5E-25 T 14-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 Tharo_0454 17b80c0406d1a0cca558f86aa879c6b9 102 PRINTS PR00606 Class ID cytochrome C signature 25 38 4.5E-25 T 14-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 Tharo_0454 17b80c0406d1a0cca558f86aa879c6b9 102 PRINTS PR00606 Class ID cytochrome C signature 40 53 4.5E-25 T 14-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 Tharo_0454 17b80c0406d1a0cca558f86aa879c6b9 102 PRINTS PR00606 Class ID cytochrome C signature 63 76 4.5E-25 T 14-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 Tharo_0454 17b80c0406d1a0cca558f86aa879c6b9 102 Gene3D G3DSA:1.10.760.10 22 102 2.1E-34 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_3122 b3ea83461897b6e78c1eafac72e85d96 294 SUPERFAMILY SSF103481 191 293 1.96E-13 T 14-10-2018 Tharo_3122 b3ea83461897b6e78c1eafac72e85d96 294 Pfam PF00892 EamA-like transporter family 155 291 1.0E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Tharo_3122 b3ea83461897b6e78c1eafac72e85d96 294 Pfam PF00892 EamA-like transporter family 11 142 2.9E-15 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Tharo_3122 b3ea83461897b6e78c1eafac72e85d96 294 SUPERFAMILY SSF103481 47 142 3.01E-10 T 14-10-2018 Tharo_0166 a41fb374c745abaa1021b5d0fb3fe4f2 55 SUPERFAMILY SSF51182 2 52 2.53E-8 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily Tharo_0166 a41fb374c745abaa1021b5d0fb3fe4f2 55 Gene3D G3DSA:2.60.120.10 1 55 2.4E-7 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Tharo_1481 72e453eebcfed8aa75971c82db747de5 597 SUPERFAMILY SSF51905 6 433 2.38E-78 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1481 72e453eebcfed8aa75971c82db747de5 597 SUPERFAMILY SSF56425 236 354 3.89E-44 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_1481 72e453eebcfed8aa75971c82db747de5 597 Pfam PF00890 FAD binding domain 9 404 8.5E-121 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_1481 72e453eebcfed8aa75971c82db747de5 597 Gene3D G3DSA:1.20.58.100 433 547 2.6E-36 T 14-10-2018 Tharo_1481 72e453eebcfed8aa75971c82db747de5 597 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 43 52 - T 14-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_1481 72e453eebcfed8aa75971c82db747de5 597 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 2.6E-5 T 14-10-2018 Tharo_1481 72e453eebcfed8aa75971c82db747de5 597 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 382 389 2.6E-5 T 14-10-2018 Tharo_1481 72e453eebcfed8aa75971c82db747de5 597 Pfam PF02910 Fumarate reductase flavoprotein C-term 462 597 3.4E-39 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_1481 72e453eebcfed8aa75971c82db747de5 597 Gene3D G3DSA:3.50.50.60 9 415 7.0E-166 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Tharo_1481 72e453eebcfed8aa75971c82db747de5 597 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 7 589 1.0E-286 T 14-10-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_1481 72e453eebcfed8aa75971c82db747de5 597 Gene3D G3DSA:3.90.700.10 246 349 7.0E-166 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_1481 72e453eebcfed8aa75971c82db747de5 597 PIRSF PIRSF000171 1 576 1.8E-42 T 14-10-2018 Tharo_1481 72e453eebcfed8aa75971c82db747de5 597 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 9 597 9.0E-240 T 14-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_1481 72e453eebcfed8aa75971c82db747de5 597 SUPERFAMILY SSF46977 451 597 3.27E-42 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Tharo_1481 72e453eebcfed8aa75971c82db747de5 597 Gene3D G3DSA:4.10.80.40 555 597 9.5E-6 T 14-10-2018 Tharo_0310 3999dd93b60a5d74f24c52d6ff469d13 117 TIGRFAM TIGR01690 ICE_RAQPRD: integrative conjugative element protein, RAQPRD family 15 107 8.0E-35 T 14-10-2018 IPR019110 Uncharacterised protein family, RAQPRD Tharo_0310 3999dd93b60a5d74f24c52d6ff469d13 117 Pfam PF09686 Plasmid protein of unknown function (Plasmid_RAQPRD) 32 106 8.1E-28 T 14-10-2018 IPR019110 Uncharacterised protein family, RAQPRD Tharo_0128 100762bf95a72d3677cc14a1cc8b648c 345 Pfam PF06250 Protein of unknown function (DUF1016) 20 331 1.5E-110 T 14-10-2018 IPR009362 Protein of unknown function DUF1016 Tharo_1370 4044113c35ffd62b958187ed0c655e64 154 Pfam PF01592 NifU-like N terminal domain 12 132 7.4E-23 T 14-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 Tharo_1370 4044113c35ffd62b958187ed0c655e64 154 Gene3D G3DSA:3.90.1010.10 3 151 8.2E-53 T 14-10-2018 Tharo_1370 4044113c35ffd62b958187ed0c655e64 154 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 8 144 7.5E-47 T 14-10-2018 Tharo_1370 4044113c35ffd62b958187ed0c655e64 154 SUPERFAMILY SSF82649 7 146 1.81E-47 T 14-10-2018 Tharo_0710 f78d1ab3c0ac1f23b2cfabe4719a268b 245 TIGRFAM TIGR03759 conj_TIGR03759: integrating conjugative element protein, PFL_4693 family 45 242 4.7E-83 T 14-10-2018 IPR022293 Integrating conjugative element protein, PFL4693 Tharo_2678 5056164c515d33d91dbf3240e56e4f78 223 Pfam PF01609 Transposase DDE domain 37 152 1.5E-6 T 14-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 Tharo_2678 5056164c515d33d91dbf3240e56e4f78 223 SUPERFAMILY SSF53098 88 163 3.03E-8 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_2494 0023ceed93e7635f13eea4e9c3472c5f 164 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 10 138 3.1E-33 T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 Tharo_2494 0023ceed93e7635f13eea4e9c3472c5f 164 Gene3D G3DSA:3.30.70.560 6 164 4.2E-50 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 Tharo_2494 0023ceed93e7635f13eea4e9c3472c5f 164 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 9 138 5.6E-40 T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 Tharo_2494 0023ceed93e7635f13eea4e9c3472c5f 164 SUPERFAMILY SSF55083 7 149 8.89E-49 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 Tharo_2210 c298ae76a6970196cbde084cc04fe6ae 208 PIRSF PIRSF006324 1 206 6.3E-54 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 Tharo_2210 c298ae76a6970196cbde084cc04fe6ae 208 Pfam PF01810 LysE type translocator 16 202 2.8E-28 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 Tharo_2911 a2e4be156cedf714a0ba37793c385a73 379 Gene3D G3DSA:2.130.10.10 29 161 1.4E-8 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Tharo_2911 a2e4be156cedf714a0ba37793c385a73 379 Gene3D G3DSA:2.130.10.10 177 364 1.6E-19 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Tharo_2911 a2e4be156cedf714a0ba37793c385a73 379 SUPERFAMILY SSF50939 60 364 1.43E-48 T 14-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 Tharo_2911 a2e4be156cedf714a0ba37793c385a73 379 Pfam PF14870 Photosynthesis system II assembly factor YCF48 74 134 5.7E-9 T 14-10-2018 IPR028203 Photosynthesis system II assembly factor Ycf48/Hcf136-like domain Tharo_2911 a2e4be156cedf714a0ba37793c385a73 379 Pfam PF14870 Photosynthesis system II assembly factor YCF48 175 301 2.5E-12 T 14-10-2018 IPR028203 Photosynthesis system II assembly factor Ycf48/Hcf136-like domain Tharo_2884 4574a8a807df04702700c7bb89db15ee 167 Gene3D G3DSA:3.30.420.10 5 162 1.4E-9 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Tharo_2884 4574a8a807df04702700c7bb89db15ee 167 SUPERFAMILY SSF53098 6 157 7.43E-6 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily Tharo_2778 b611e208df12a4177759e69cb6dd56a5 169 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 8 122 5.7E-22 T 14-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 Tharo_2778 b611e208df12a4177759e69cb6dd56a5 169 Gene3D G3DSA:3.40.50.1000 1 168 1.9E-54 T 14-10-2018 IPR023214 HAD superfamily Tharo_2778 b611e208df12a4177759e69cb6dd56a5 169 SUPERFAMILY SSF56784 4 166 1.12E-39 T 14-10-2018 IPR036412 HAD-like superfamily Tharo_2778 b611e208df12a4177759e69cb6dd56a5 169 TIGRFAM TIGR02726 phenyl_P_delta: phenylphosphate carboxylase, delta subunit 1 169 5.6E-115 T 14-10-2018 IPR014098 Phenylphosphate carboxylase, delta subunit Tharo_2778 b611e208df12a4177759e69cb6dd56a5 169 Pfam PF08282 haloacid dehalogenase-like hydrolase 83 141 1.7E-11 T 14-10-2018 Tharo_2778 b611e208df12a4177759e69cb6dd56a5 169 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 7 159 6.9E-48 T 14-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 Tharo_2778 b611e208df12a4177759e69cb6dd56a5 169 PIRSF PIRSF006118 1 169 2.8E-69 T 14-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 Tharo_1387 c392e1e511bcff2010ebfe4f3a8eb50f 396 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 175 349 1.8E-24 T 14-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 Tharo_1387 c392e1e511bcff2010ebfe4f3a8eb50f 396 SMART SM00359 2 87 2.1E-11 T 14-10-2018 IPR002478 PUA domain GO:0003723 Tharo_1387 c392e1e511bcff2010ebfe4f3a8eb50f 396 SUPERFAMILY SSF53335 86 392 2.26E-63 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_1387 c392e1e511bcff2010ebfe4f3a8eb50f 396 Gene3D G3DSA:3.30.750.80 72 180 3.4E-34 T 14-10-2018 Tharo_1387 c392e1e511bcff2010ebfe4f3a8eb50f 396 Gene3D G3DSA:3.40.50.150 182 395 4.8E-70 T 14-10-2018 Tharo_1387 c392e1e511bcff2010ebfe4f3a8eb50f 396 SUPERFAMILY SSF88697 1 68 6.84E-16 T 14-10-2018 IPR015947 PUA-like superfamily Tharo_1387 c392e1e511bcff2010ebfe4f3a8eb50f 396 Gene3D G3DSA:2.30.130.10 1 70 6.9E-27 T 14-10-2018 IPR036974 PUA domain superfamily GO:0003723 Tharo_0342 99de2f5f43a5deb6f0ee1dabd7862d59 89 Pfam PF01313 Bacterial export proteins, family 3 5 78 3.9E-29 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 Tharo_0342 99de2f5f43a5deb6f0ee1dabd7862d59 89 PIRSF PIRSF004669 1 89 3.1E-32 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 Tharo_0342 99de2f5f43a5deb6f0ee1dabd7862d59 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 1.0E-22 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 Tharo_0342 99de2f5f43a5deb6f0ee1dabd7862d59 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 1.0E-22 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 Tharo_0342 99de2f5f43a5deb6f0ee1dabd7862d59 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 1.0E-22 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 Tharo_0342 99de2f5f43a5deb6f0ee1dabd7862d59 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 2 87 5.3E-30 T 14-10-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 Tharo_1633 65fd6af9411e094cc661c7a2565e614d 192 PIRSF PIRSF000847 1 191 3.0E-46 T 14-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 Tharo_1633 65fd6af9411e094cc661c7a2565e614d 192 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4 182 1.4E-52 T 14-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 Tharo_1633 65fd6af9411e094cc661c7a2565e614d 192 Gene3D G3DSA:1.20.120.1760 4 178 1.9E-13 T 14-10-2018 Tharo_1633 65fd6af9411e094cc661c7a2565e614d 192 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 54 76 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Tharo_1633 65fd6af9411e094cc661c7a2565e614d 192 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 76 1.4E-16 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Tharo_1519 fa8c8fcf0fc66ac9af9e6c3a98bafb5b 117 SUPERFAMILY SSF57783 3 36 4.08E-14 T 14-10-2018 Tharo_1519 fa8c8fcf0fc66ac9af9e6c3a98bafb5b 117 SUPERFAMILY SSF82057 47 116 2.7E-29 T 14-10-2018 Tharo_1519 fa8c8fcf0fc66ac9af9e6c3a98bafb5b 117 Pfam PF03831 PhnA domain 51 116 3.8E-34 T 14-10-2018 IPR013988 PhnA protein, C-terminal Tharo_1519 fa8c8fcf0fc66ac9af9e6c3a98bafb5b 117 Gene3D G3DSA:2.30.30.40 47 117 2.7E-35 T 14-10-2018 Tharo_1519 fa8c8fcf0fc66ac9af9e6c3a98bafb5b 117 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 3 116 7.2E-47 T 14-10-2018 IPR004624 PhnA protein Tharo_1519 fa8c8fcf0fc66ac9af9e6c3a98bafb5b 117 Gene3D G3DSA:2.20.25.10 1 42 2.8E-19 T 14-10-2018 Tharo_1519 fa8c8fcf0fc66ac9af9e6c3a98bafb5b 117 Pfam PF08274 PhnA Zinc-Ribbon 3 32 4.2E-16 T 14-10-2018 IPR013987 PhnA protein, N-terminal Tharo_2719 4099ba20a67db9aadc2cb9b21d0288bb 109 Gene3D G3DSA:3.90.470.10 1 109 3.3E-42 T 14-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 Tharo_2719 4099ba20a67db9aadc2cb9b21d0288bb 109 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 14-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2719 4099ba20a67db9aadc2cb9b21d0288bb 109 SUPERFAMILY SSF54843 1 109 2.49E-40 T 14-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 Tharo_2719 4099ba20a67db9aadc2cb9b21d0288bb 109 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 109 24.942 T 14-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2719 4099ba20a67db9aadc2cb9b21d0288bb 109 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 1.3E-34 T 14-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 Tharo_2719 4099ba20a67db9aadc2cb9b21d0288bb 109 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 1.1E-43 T 14-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Tharo_2833 a549fa4b32cda4bf886136e1089b1688 152 SUPERFAMILY SSF53850 31 139 2.99E-5 T 14-10-2018 Tharo_2975 e806561686c971c8cf4abd3f46b3e29c 647 Pfam PF01464 Transglycosylase SLT domain 489 591 6.2E-20 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 Tharo_2975 e806561686c971c8cf4abd3f46b3e29c 647 SUPERFAMILY SSF48435 27 476 4.58E-101 T 14-10-2018 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 Tharo_2975 e806561686c971c8cf4abd3f46b3e29c 647 Gene3D G3DSA:1.10.530.10 474 637 5.1E-40 T 14-10-2018 Tharo_2975 e806561686c971c8cf4abd3f46b3e29c 647 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 501 529 - T 14-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 Tharo_2975 e806561686c971c8cf4abd3f46b3e29c 647 Gene3D G3DSA:1.25.20.10 31 387 1.6E-72 T 14-10-2018 Tharo_2975 e806561686c971c8cf4abd3f46b3e29c 647 Pfam PF14718 Soluble lytic murein transglycosylase L domain 407 462 3.7E-7 T 14-10-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 Tharo_2975 e806561686c971c8cf4abd3f46b3e29c 647 SUPERFAMILY SSF53955 479 637 1.0E-40 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily Tharo_1688 7c7ca0f70c56b17e7f110addd25d42c1 96 Gene3D G3DSA:3.30.70.2340 1 94 2.0E-34 T 14-10-2018 Tharo_1688 7c7ca0f70c56b17e7f110addd25d42c1 96 Pfam PF12112 Protein of unknown function (DUF3579) 5 88 1.8E-35 T 14-10-2018 IPR021969 Protein of unknown function DUF3579 Tharo_2666 16a1a817af175aee4592437d41ac0935 516 Pfam PF04293 SpoVR like protein 22 453 4.1E-175 T 14-10-2018 IPR007390 Sporulation stage V, protein R Tharo_1759 a2dfa1e8e3e99857110f7da242fe16f7 266 Pfam PF07728 AAA domain (dynein-related subfamily) 33 166 1.3E-34 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 Tharo_1759 a2dfa1e8e3e99857110f7da242fe16f7 266 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 179 262 4.9E-27 T 14-10-2018 IPR013615 CbbQ/NirQ/NorQ, C-terminal Tharo_1759 a2dfa1e8e3e99857110f7da242fe16f7 266 SUPERFAMILY SSF52540 23 217 1.22E-31 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_1759 a2dfa1e8e3e99857110f7da242fe16f7 266 Gene3D G3DSA:3.40.50.300 17 184 4.6E-29 T 14-10-2018 Tharo_1841 e7a0bb2cda789f500fdd38fa45f872cd 151 SUPERFAMILY SSF47240 8 149 3.64E-32 T 14-10-2018 IPR009078 Ferritin-like superfamily Tharo_1841 e7a0bb2cda789f500fdd38fa45f872cd 151 Gene3D G3DSA:1.20.1260.10 1 149 4.8E-54 T 14-10-2018 IPR012347 Ferritin-like Tharo_1841 e7a0bb2cda789f500fdd38fa45f872cd 151 Pfam PF02915 Rubrerythrin 8 144 1.3E-10 T 14-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 Tharo_1944 97bac3d5b1df558c250cddb4e71f7ebd 133 SUPERFAMILY SSF88723 1 131 1.68E-34 T 14-10-2018 IPR029060 PIN-like domain superfamily Tharo_1944 97bac3d5b1df558c250cddb4e71f7ebd 133 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 130 12.263 T 14-10-2018 IPR022907 VapC family GO:0004540 Tharo_1944 97bac3d5b1df558c250cddb4e71f7ebd 133 Gene3D G3DSA:3.40.50.1010 1 132 1.3E-37 T 14-10-2018 Tharo_1944 97bac3d5b1df558c250cddb4e71f7ebd 133 Pfam PF01850 PIN domain 4 123 9.8E-17 T 14-10-2018 IPR002716 PIN domain Tharo_3064 d606ed5a9bb64b099328d5120a9a317f 456 Pfam PF07044 Protein of unknown function (DUF1329) 87 450 5.5E-127 T 14-10-2018 IPR010752 Protein of unknown function DUF1329 Tharo_2313 490cec09bcced27a1b0d578199c699f6 144 SUPERFAMILY SSF51283 9 143 1.7E-49 T 14-10-2018 IPR036157 dUTPase-like superfamily Tharo_2313 490cec09bcced27a1b0d578199c699f6 144 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 1 143 32.758 T 14-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 Tharo_2313 490cec09bcced27a1b0d578199c699f6 144 Pfam PF00692 dUTPase 12 142 1.8E-37 T 14-10-2018 IPR029054 dUTPase-like Tharo_2313 490cec09bcced27a1b0d578199c699f6 144 TIGRFAM TIGR00576 dut: dUTP diphosphatase 9 143 9.0E-46 T 14-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 Tharo_2313 490cec09bcced27a1b0d578199c699f6 144 Gene3D G3DSA:2.70.40.10 1 144 2.3E-47 T 14-10-2018 IPR036157 dUTPase-like superfamily Tharo_2679 17ca991d85f7b9b432e00b4187648454 95 Pfam PF09907 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system 14 86 1.1E-32 T 14-10-2018 IPR018669 Toxin-antitoxin system, toxin component, HigB, putative GO:0016788 Tharo_1104 4e5437e2c17083aa42866fd1daaa7ed3 319 Gene3D G3DSA:3.30.360.10 125 303 3.1E-55 T 14-10-2018 Tharo_1104 4e5437e2c17083aa42866fd1daaa7ed3 319 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 124 6.8E-23 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 Tharo_1104 4e5437e2c17083aa42866fd1daaa7ed3 319 Gene3D G3DSA:3.40.50.720 5 297 3.1E-55 T 14-10-2018 Tharo_1104 4e5437e2c17083aa42866fd1daaa7ed3 319 SUPERFAMILY SSF51735 2 144 7.24E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1104 4e5437e2c17083aa42866fd1daaa7ed3 319 SUPERFAMILY SSF55347 129 261 3.05E-10 T 14-10-2018 Tharo_0830 834441e8f3aa5b503c20344b2ef7015a 374 Pfam PF13286 Phosphohydrolase-associated domain 281 366 5.4E-28 T 14-10-2018 IPR026875 Phosphohydrolase-associated domain Tharo_0830 834441e8f3aa5b503c20344b2ef7015a 374 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 27 369 3.0E-90 T 14-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 Tharo_0830 834441e8f3aa5b503c20344b2ef7015a 374 Pfam PF01966 HD domain 64 194 4.3E-15 T 14-10-2018 IPR006674 HD domain Tharo_0830 834441e8f3aa5b503c20344b2ef7015a 374 SMART SM00471 60 204 6.2E-11 T 14-10-2018 IPR003607 HD/PDEase domain Tharo_0830 834441e8f3aa5b503c20344b2ef7015a 374 SUPERFAMILY SSF109604 16 368 9.24E-88 T 14-10-2018 Tharo_0830 834441e8f3aa5b503c20344b2ef7015a 374 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 4 368 38.484 T 14-10-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 Tharo_0830 834441e8f3aa5b503c20344b2ef7015a 374 Gene3D G3DSA:1.10.3210.10 1 369 3.3E-131 T 14-10-2018 Tharo_2674 1b6e72f7501b747f954df5138f177b94 112 Pfam PF05717 IS66 Orf2 like protein 6 102 1.1E-36 T 14-10-2018 IPR008878 Transposase IS66, Orf2 Tharo_0224 1b6e72f7501b747f954df5138f177b94 112 Pfam PF05717 IS66 Orf2 like protein 6 102 1.1E-36 T 14-10-2018 IPR008878 Transposase IS66, Orf2 Tharo_0320 1b6e72f7501b747f954df5138f177b94 112 Pfam PF05717 IS66 Orf2 like protein 6 102 1.1E-36 T 14-10-2018 IPR008878 Transposase IS66, Orf2 Tharo_1622 17baf9e86950c81bda1c971ca8c234a0 381 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 249 266 - T 14-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 Tharo_1622 17baf9e86950c81bda1c971ca8c234a0 381 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 11 356 50.494 T 14-10-2018 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 Tharo_1622 17baf9e86950c81bda1c971ca8c234a0 381 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 13 298 6.2E-70 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Tharo_1622 17baf9e86950c81bda1c971ca8c234a0 381 SUPERFAMILY SSF51445 10 305 1.26E-79 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily Tharo_1622 17baf9e86950c81bda1c971ca8c234a0 381 Gene3D G3DSA:3.20.20.300 2 347 9.7E-112 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 Tharo_1366 c46860dd42e066414bd4d634900ec765 417 Gene3D G3DSA:1.20.1250.20 216 410 8.2E-7 T 14-10-2018 Tharo_1366 c46860dd42e066414bd4d634900ec765 417 Pfam PF07690 Major Facilitator Superfamily 23 363 4.3E-30 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_1366 c46860dd42e066414bd4d634900ec765 417 Gene3D G3DSA:1.20.1250.20 12 196 2.1E-31 T 14-10-2018 Tharo_1366 c46860dd42e066414bd4d634900ec765 417 SUPERFAMILY SSF103473 11 403 2.75E-47 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_0249 0b4799180f7709304efae3e10090d580 241 Pfam PF02417 Chromate transporter 25 189 9.3E-29 T 14-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 Tharo_3456 30b8025f95b9224b0a1ed55d6bb6c567 146 ProDom PD033334 TRAM PLASMID TRANSFER CONJUGATION ESSENTIAL SYSTEM SEQUENCING DIRECT DNA CONJUGAL 5 128 2.0E-48 T 14-10-2018 Tharo_3456 30b8025f95b9224b0a1ed55d6bb6c567 146 Pfam PF11657 Transcriptional activator TraM 5 144 4.1E-63 T 14-10-2018 IPR028140 Protein TraM GO:0009372 Tharo_2122 78e2396497d09fac22c7a6adee88b912 529 Gene3D G3DSA:3.40.50.300 2 223 1.6E-42 T 14-10-2018 Tharo_1967 c27d481aec128318b958dad047c1b4f8 200 Gene3D G3DSA:1.10.357.10 3 199 2.6E-16 T 14-10-2018 Tharo_1967 c27d481aec128318b958dad047c1b4f8 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.1E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_1967 c27d481aec128318b958dad047c1b4f8 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.1E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_1967 c27d481aec128318b958dad047c1b4f8 200 SUPERFAMILY SSF46689 8 74 3.28E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_1967 c27d481aec128318b958dad047c1b4f8 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 60 6.1E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_3421 2709e7a43ae187e20b60d858bd9a12c9 195 Pfam PF07424 TrbM 27 177 5.6E-60 T 14-10-2018 IPR009989 TrbM Tharo_3261 9ffe56366358089c8f51fbe729c69ff9 209 Gene3D G3DSA:1.10.510.10 94 178 3.2E-5 T 14-10-2018 Tharo_3261 9ffe56366358089c8f51fbe729c69ff9 209 SUPERFAMILY SSF56112 33 157 2.05E-14 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Tharo_0252 fb200381482fbccf4a28aebb865cc5a3 204 Gene3D G3DSA:3.40.50.300 7 180 4.9E-66 T 14-10-2018 Tharo_0252 fb200381482fbccf4a28aebb865cc5a3 204 Hamap MF_00328 Guanylate kinase [gmk]. 1 184 36.997 T 14-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 Tharo_0252 fb200381482fbccf4a28aebb865cc5a3 204 SMART SM00072 2 184 1.1E-61 T 14-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit Tharo_0252 fb200381482fbccf4a28aebb865cc5a3 204 Gene3D G3DSA:3.30.63.10 34 93 4.9E-66 T 14-10-2018 Tharo_0252 fb200381482fbccf4a28aebb865cc5a3 204 ProSitePatterns PS00856 Guanylate kinase-like signature. 37 54 - T 14-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 Tharo_0252 fb200381482fbccf4a28aebb865cc5a3 204 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 3 181 6.7E-71 T 14-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 Tharo_0252 fb200381482fbccf4a28aebb865cc5a3 204 Pfam PF00625 Guanylate kinase 5 181 1.7E-45 T 14-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit Tharo_0252 fb200381482fbccf4a28aebb865cc5a3 204 SUPERFAMILY SSF52540 2 186 2.03E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0999 43e6ef03f97a3c2835fe3a5f2cfa2cab 293 PIRSF PIRSF005651 1 293 2.7E-96 T 14-10-2018 IPR010200 HflC GO:0016021|GO:0052547 Tharo_0999 43e6ef03f97a3c2835fe3a5f2cfa2cab 293 SMART SM00244 21 185 4.6E-36 T 14-10-2018 IPR001107 Band 7 domain Tharo_0999 43e6ef03f97a3c2835fe3a5f2cfa2cab 293 SUPERFAMILY SSF117892 53 191 4.05E-32 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily Tharo_0999 43e6ef03f97a3c2835fe3a5f2cfa2cab 293 TIGRFAM TIGR01932 hflC: HflC protein 142 285 3.6E-48 T 14-10-2018 IPR010200 HflC GO:0016021|GO:0052547 Tharo_0999 43e6ef03f97a3c2835fe3a5f2cfa2cab 293 Pfam PF01145 SPFH domain / Band 7 family 25 196 3.8E-28 T 14-10-2018 IPR001107 Band 7 domain Tharo_0999 43e6ef03f97a3c2835fe3a5f2cfa2cab 293 PRINTS PR00721 Stomatin signature 77 98 1.8E-5 T 14-10-2018 IPR001972 Stomatin family GO:0016020 Tharo_0999 43e6ef03f97a3c2835fe3a5f2cfa2cab 293 PRINTS PR00721 Stomatin signature 28 50 1.8E-5 T 14-10-2018 IPR001972 Stomatin family GO:0016020 Tharo_0999 43e6ef03f97a3c2835fe3a5f2cfa2cab 293 PRINTS PR00721 Stomatin signature 161 179 1.8E-5 T 14-10-2018 IPR001972 Stomatin family GO:0016020 Tharo_0999 43e6ef03f97a3c2835fe3a5f2cfa2cab 293 PRINTS PR00721 Stomatin signature 180 201 1.8E-5 T 14-10-2018 IPR001972 Stomatin family GO:0016020 Tharo_0999 43e6ef03f97a3c2835fe3a5f2cfa2cab 293 Gene3D G3DSA:3.30.479.30 50 187 7.5E-27 T 14-10-2018 Tharo_2074 ba0b245fa5de4ba4531bd0e6ff442cb3 361 SMART SM00771 211 336 2.5E-32 T 14-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 Tharo_2074 ba0b245fa5de4ba4531bd0e6ff442cb3 361 Gene3D G3DSA:3.30.1400.10 212 343 6.8E-22 T 14-10-2018 IPR036765 ZipA, C-terminal FtsZ-binding domain superfamily GO:0090529 Tharo_2074 ba0b245fa5de4ba4531bd0e6ff442cb3 361 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 215 335 2.3E-27 T 14-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 Tharo_2074 ba0b245fa5de4ba4531bd0e6ff442cb3 361 SUPERFAMILY SSF64383 210 344 5.36E-31 T 14-10-2018 IPR036765 ZipA, C-terminal FtsZ-binding domain superfamily GO:0090529 Tharo_2074 ba0b245fa5de4ba4531bd0e6ff442cb3 361 ProDom PD035754 CELL DIVISION MEMBRANE ZIPA SEPTATION TRANSMEMBRANE HOMOLOG INNER CYCLE ZIPA 215 343 4.0E-35 T 14-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 Tharo_2329 1c52b4f3b28431eee401051777015336 264 TIGRFAM TIGR00067 glut_race: glutamate racemase 4 251 1.1E-70 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Tharo_2329 1c52b4f3b28431eee401051777015336 264 Gene3D G3DSA:3.40.50.1860 94 206 9.5E-89 T 14-10-2018 Tharo_2329 1c52b4f3b28431eee401051777015336 264 SUPERFAMILY SSF53681 3 104 2.13E-32 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Tharo_2329 1c52b4f3b28431eee401051777015336 264 Pfam PF01177 Asp/Glu/Hydantoin racemase 4 212 2.9E-34 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Tharo_2329 1c52b4f3b28431eee401051777015336 264 SUPERFAMILY SSF53681 109 262 2.62E-39 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Tharo_2329 1c52b4f3b28431eee401051777015336 264 Gene3D G3DSA:3.40.50.1860 2 251 9.5E-89 T 14-10-2018 Tharo_2329 1c52b4f3b28431eee401051777015336 264 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 179 189 - T 14-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Tharo_2329 1c52b4f3b28431eee401051777015336 264 Hamap MF_00258 Glutamate racemase [murI]. 2 255 36.462 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Tharo_0937 91bb4fcf450cc7c86f08212871354c2f 378 Pfam PF00534 Glycosyl transferases group 1 196 353 1.5E-27 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 Tharo_0937 91bb4fcf450cc7c86f08212871354c2f 378 Pfam PF13439 Glycosyltransferase Family 4 21 177 1.9E-16 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Tharo_0937 91bb4fcf450cc7c86f08212871354c2f 378 Gene3D G3DSA:3.40.50.2000 175 355 5.1E-59 T 14-10-2018 Tharo_0937 91bb4fcf450cc7c86f08212871354c2f 378 SUPERFAMILY SSF53756 20 375 2.15E-75 T 14-10-2018 Tharo_0937 91bb4fcf450cc7c86f08212871354c2f 378 Gene3D G3DSA:3.40.50.2000 21 371 5.1E-59 T 14-10-2018 Tharo_1764 2762077ec1c9621d3276cca4b3cf0c52 141 SUPERFAMILY SSF46626 46 137 6.76E-18 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_1764 2762077ec1c9621d3276cca4b3cf0c52 141 Pfam PF00034 Cytochrome c 49 126 2.4E-11 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_1764 2762077ec1c9621d3276cca4b3cf0c52 141 Gene3D G3DSA:1.10.760.10 1 141 1.6E-40 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Tharo_0263 128d17d2d7d9557a0faf0361fb547514 258 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 105 125 3.0E-42 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_0263 128d17d2d7d9557a0faf0361fb547514 258 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 161 187 3.0E-42 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_0263 128d17d2d7d9557a0faf0361fb547514 258 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 50 67 3.0E-42 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_0263 128d17d2d7d9557a0faf0361fb547514 258 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 126 146 3.0E-42 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_0263 128d17d2d7d9557a0faf0361fb547514 258 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 67 87 3.0E-42 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_0263 128d17d2d7d9557a0faf0361fb547514 258 Pfam PF01578 Cytochrome C assembly protein 37 189 6.2E-26 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 Tharo_0263 128d17d2d7d9557a0faf0361fb547514 258 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 50 232 3.6E-65 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_3243 794fa7b7a0def4a298d9f5080755ef3c 319 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 6 312 5.7E-117 T 14-10-2018 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 Tharo_3243 794fa7b7a0def4a298d9f5080755ef3c 319 Gene3D G3DSA:3.40.1190.20 3 309 3.9E-106 T 14-10-2018 IPR029056 Ribokinase-like Tharo_3243 794fa7b7a0def4a298d9f5080755ef3c 319 SUPERFAMILY SSF53613 12 310 1.56E-51 T 14-10-2018 IPR029056 Ribokinase-like Tharo_3243 794fa7b7a0def4a298d9f5080755ef3c 319 Pfam PF00294 pfkB family carbohydrate kinase 12 305 6.9E-40 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB Tharo_2753 7eafcff3011c41e9e2bc5d0696fd9a7b 114 Pfam PF07811 TadE-like protein 1 34 1.7E-7 T 14-10-2018 IPR012495 TadE-like Tharo_1914 365e986ee8b44e4c2c9a40d7136ed950 124 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 22 123 5.9E-35 T 14-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1914 365e986ee8b44e4c2c9a40d7136ed950 124 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 124 18.998 T 14-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 Tharo_1914 365e986ee8b44e4c2c9a40d7136ed950 124 Gene3D G3DSA:1.20.58.1610 1 124 2.6E-40 T 14-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_2000 523107aca2e5fcaa8a333bfc830bfa82 422 SUPERFAMILY SSF51726 18 420 5.58E-35 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 Tharo_2000 523107aca2e5fcaa8a333bfc830bfa82 422 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 219 420 2.2E-22 T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 Tharo_1141 8adb2392d1bdde3c4f23f700093a4ce4 323 Pfam PF02653 Branched-chain amino acid transport system / permease component 29 296 9.4E-40 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Tharo_3365 8adb2392d1bdde3c4f23f700093a4ce4 323 Pfam PF02653 Branched-chain amino acid transport system / permease component 29 296 9.4E-40 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Tharo_0465 9f103fce15ee660344561448c8716bbc 207 Gene3D G3DSA:1.10.3480.10 10 205 4.8E-34 T 14-10-2018 Tharo_0465 9f103fce15ee660344561448c8716bbc 207 Pfam PF02613 Nitrate reductase delta subunit 52 170 4.7E-22 T 14-10-2018 IPR020945 DMSO/Nitrate reductase chaperone Tharo_0465 9f103fce15ee660344561448c8716bbc 207 SUPERFAMILY SSF89155 12 202 2.62E-42 T 14-10-2018 IPR036411 TorD-like superfamily Tharo_3100 9b40127dea938cbc7b9283ed923f8a77 392 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 3 370 6.8E-65 T 14-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 Tharo_3100 9b40127dea938cbc7b9283ed923f8a77 392 Pfam PF07690 Major Facilitator Superfamily 9 337 2.2E-41 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_3100 9b40127dea938cbc7b9283ed923f8a77 392 Gene3D G3DSA:1.20.1720.10 3 385 1.4E-97 T 14-10-2018 Tharo_3100 9b40127dea938cbc7b9283ed923f8a77 392 SUPERFAMILY SSF103473 2 386 6.02E-58 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_3174 06d0439402918e9384848fc02b9c6cbe 491 Pfam PF11067 Protein of unknown function (DUF2868) 162 466 4.4E-76 T 14-10-2018 IPR021296 Protein of unknown function DUF2868 Tharo_2285 7ab84a677e7df894383b937105c2e2c9 235 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 8 215 7.9E-53 T 14-10-2018 IPR039447 Urease accessory protein UreH-like, transmembrane domain Tharo_2715 63194468ef5b7a525cbd6938133563ad 89 Pfam PF00366 Ribosomal protein S17 14 81 6.4E-31 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2715 63194468ef5b7a525cbd6938133563ad 89 Gene3D G3DSA:2.40.50.140 8 89 1.2E-33 T 14-10-2018 Tharo_2715 63194468ef5b7a525cbd6938133563ad 89 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 9 84 23.994 T 14-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2715 63194468ef5b7a525cbd6938133563ad 89 ProSitePatterns PS00056 Ribosomal protein S17 signature. 60 72 - T 14-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_2715 63194468ef5b7a525cbd6938133563ad 89 SUPERFAMILY SSF50249 9 86 3.04E-31 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold Tharo_2715 63194468ef5b7a525cbd6938133563ad 89 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 9 79 8.7E-35 T 14-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2715 63194468ef5b7a525cbd6938133563ad 89 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 9 79 4.0E-32 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2715 63194468ef5b7a525cbd6938133563ad 89 PRINTS PR00973 Ribosomal protein S17 family signature 70 77 1.6E-12 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2715 63194468ef5b7a525cbd6938133563ad 89 PRINTS PR00973 Ribosomal protein S17 family signature 28 51 1.6E-12 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2715 63194468ef5b7a525cbd6938133563ad 89 PRINTS PR00973 Ribosomal protein S17 family signature 60 70 1.6E-12 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2232 8c6b3b18750496da93ee083d0d9ac534 169 Pfam PF13518 Helix-turn-helix domain 63 116 7.6E-6 T 14-10-2018 Tharo_2949 d61ea6be4d561cb38c2e8ad95c742a45 350 Pfam PF00753 Metallo-beta-lactamase superfamily 49 262 6.7E-21 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_2949 d61ea6be4d561cb38c2e8ad95c742a45 350 Gene3D G3DSA:3.60.15.10 29 290 8.2E-60 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_2949 d61ea6be4d561cb38c2e8ad95c742a45 350 SMART SM00849 48 262 1.3E-22 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_2949 d61ea6be4d561cb38c2e8ad95c742a45 350 SUPERFAMILY SSF56281 13 345 7.99E-71 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_2949 d61ea6be4d561cb38c2e8ad95c742a45 350 Gene3D G3DSA:1.10.10.10 292 346 5.9E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2576 ed6a9c1965a1a06141b146f5c4523786 524 Pfam PF02661 Fic/DOC family 240 343 1.1E-11 T 14-10-2018 IPR003812 Fido domain Tharo_2576 ed6a9c1965a1a06141b146f5c4523786 524 SUPERFAMILY SSF140931 239 376 4.19E-13 T 14-10-2018 IPR036597 Fido-like domain superfamily Tharo_2576 ed6a9c1965a1a06141b146f5c4523786 524 Gene3D G3DSA:1.10.3290.10 183 395 1.7E-20 T 14-10-2018 IPR036597 Fido-like domain superfamily Tharo_2974 40ec4c1459b4124a4ebbfc63e7f507e9 189 Gene3D G3DSA:3.40.50.10420 1 187 3.4E-36 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily Tharo_2974 40ec4c1459b4124a4ebbfc63e7f507e9 189 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 1 172 1.5E-32 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase Tharo_2974 40ec4c1459b4124a4ebbfc63e7f507e9 189 PIRSF PIRSF006806 1 175 1.4E-20 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase Tharo_2974 40ec4c1459b4124a4ebbfc63e7f507e9 189 SUPERFAMILY SSF100950 2 180 2.93E-41 T 14-10-2018 IPR037171 NagB/RpiA transferase-like Tharo_2974 40ec4c1459b4124a4ebbfc63e7f507e9 189 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 2 172 2.7E-16 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase Tharo_1457 f7df2276d099a0f604b2610ffcee9d3a 423 Pfam PF01435 Peptidase family M48 209 410 2.6E-37 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 Tharo_1457 f7df2276d099a0f604b2610ffcee9d3a 423 Gene3D G3DSA:3.30.2010.10 204 286 1.4E-29 T 14-10-2018 Tharo_1457 f7df2276d099a0f604b2610ffcee9d3a 423 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 26 204 4.1E-46 T 14-10-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 Tharo_0681 4829e3e4bf11db4d2798b24721f7ece0 344 Pfam PF13387 Domain of unknown function (DUF4105) 128 280 2.4E-47 T 14-10-2018 IPR025178 Domain of unknown function DUF4105 Tharo_0870 02b7aa4c6bf11c5ece81327d0645eb62 506 Pfam PF00361 Proton-conducting membrane transporter 127 422 4.7E-41 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_0870 02b7aa4c6bf11c5ece81327d0645eb62 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 131 150 5.1E-13 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_0870 02b7aa4c6bf11c5ece81327d0645eb62 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 234 258 5.1E-13 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_0870 02b7aa4c6bf11c5ece81327d0645eb62 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 161 185 5.1E-13 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_0870 02b7aa4c6bf11c5ece81327d0645eb62 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 326 345 5.1E-13 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_0870 02b7aa4c6bf11c5ece81327d0645eb62 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 379 405 5.1E-13 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_0385 8acc03654900733974f2bcd558fb36b9 82 SUPERFAMILY SSF47598 1 41 6.3E-6 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Tharo_0385 8acc03654900733974f2bcd558fb36b9 82 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 41 2.8E-7 T 14-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 Tharo_1600 a13c3f3af9d55a9b1368ba85b8887d38 340 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 340 156.187 T 14-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 Tharo_1600 a13c3f3af9d55a9b1368ba85b8887d38 340 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 6 337 8.2E-114 T 14-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 Tharo_1600 a13c3f3af9d55a9b1368ba85b8887d38 340 PIRSF PIRSF002465 3 340 1.0E-131 T 14-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 Tharo_1600 a13c3f3af9d55a9b1368ba85b8887d38 340 Gene3D G3DSA:3.40.718.10 4 340 1.7E-131 T 14-10-2018 Tharo_1600 a13c3f3af9d55a9b1368ba85b8887d38 340 SUPERFAMILY SSF53659 5 335 1.48E-107 T 14-10-2018 Tharo_1600 a13c3f3af9d55a9b1368ba85b8887d38 340 Pfam PF02504 Fatty acid synthesis protein 5 327 4.1E-108 T 14-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 Tharo_1789 0d42920e09b875e0465d703dcb37b4cc 287 Gene3D G3DSA:3.90.1280.10 233 283 4.6E-8 T 14-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 Tharo_1789 0d42920e09b875e0465d703dcb37b4cc 287 SUPERFAMILY SSF64397 9 227 3.27E-57 T 14-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 Tharo_1789 0d42920e09b875e0465d703dcb37b4cc 287 SUPERFAMILY SSF118352 225 282 1.83E-9 T 14-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 Tharo_1789 0d42920e09b875e0465d703dcb37b4cc 287 Pfam PF01430 Hsp33 protein 9 273 2.1E-67 T 14-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 Tharo_1789 0d42920e09b875e0465d703dcb37b4cc 287 Gene3D G3DSA:3.55.30.10 7 175 5.6E-49 T 14-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 Tharo_1789 0d42920e09b875e0465d703dcb37b4cc 287 PIRSF PIRSF005261 2 283 2.6E-69 T 14-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 Tharo_1789 0d42920e09b875e0465d703dcb37b4cc 287 Gene3D G3DSA:1.10.287.480 177 226 1.0E-14 T 14-10-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain superfamily Tharo_0012 f3f3884ed81955f4f9a431eab1bbf019 89 SUPERFAMILY SSF47598 6 48 3.89E-9 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Tharo_0012 f3f3884ed81955f4f9a431eab1bbf019 89 Pfam PF01402 Ribbon-helix-helix protein, copG family 9 46 1.6E-10 T 14-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 Tharo_3419 1d9fc530b6e573fb4c870f5533166baf 71 TIGRFAM TIGR04359 TrbK_RP4: entry exclusion lipoprotein TrbK 9 70 1.8E-6 T 14-10-2018 IPR027584 Entry exclusion lipoprotein TrbK Tharo_1924 3edc16c859fc5127c2b7e799caa4fcff 101 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 2 101 20.386 T 14-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 Tharo_1924 3edc16c859fc5127c2b7e799caa4fcff 101 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7 96 2.7E-22 T 14-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like Tharo_0747 6d65340836bc5365492e3d07af4f924c 1329 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 978 1328 3.0E-45 T 14-10-2018 IPR007452 Translocation and assembly module TamB Tharo_1193 a6d6ff724a571867fdb87e32af5a5d49 229 Gene3D G3DSA:3.30.70.1070 160 228 3.3E-15 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 Tharo_1193 a6d6ff724a571867fdb87e32af5a5d49 229 SUPERFAMILY SSF110997 159 225 1.57E-17 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 Tharo_1193 a6d6ff724a571867fdb87e32af5a5d49 229 Pfam PF05036 Sporulation related domain 160 226 7.4E-17 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 Tharo_3431 62a3de5abc42eadbac30d10421eb8b49 83 SUPERFAMILY SSF89447 1 41 6.1E-6 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily Tharo_3431 62a3de5abc42eadbac30d10421eb8b49 83 SMART SM00966 4 50 6.5E-5 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Tharo_3431 62a3de5abc42eadbac30d10421eb8b49 83 Gene3D G3DSA:2.10.260.10 2 44 3.9E-6 T 14-10-2018 Tharo_2790 7100e9c2654cfdf90b4b172754debaf6 469 SUPERFAMILY SSF102114 170 394 3.34E-9 T 14-10-2018 Tharo_2790 7100e9c2654cfdf90b4b172754debaf6 469 Gene3D G3DSA:3.20.20.70 63 398 1.9E-70 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_0808 c287559d0dcf802a7902bdfe8f0765dd 74 SMART SM00966 3 46 0.0021 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Tharo_0808 c287559d0dcf802a7902bdfe8f0765dd 74 SUPERFAMILY SSF89447 2 56 1.12E-7 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily Tharo_1670 aabbed04dbc8ea08f74c772de6aeacb6 664 Pfam PF01136 Peptidase family U32 84 315 3.7E-71 T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 Tharo_1670 aabbed04dbc8ea08f74c772de6aeacb6 664 Pfam PF12392 Collagenase 402 529 4.2E-21 T 14-10-2018 IPR020988 Peptidase U32, collagenase Tharo_1670 aabbed04dbc8ea08f74c772de6aeacb6 664 ProSitePatterns PS01276 Peptidase family U32 signature. 167 185 - T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 Tharo_1404 ed99e2d0a35943fd9772a1c8353e5652 233 Pfam PF01988 VIT family 19 226 1.9E-51 T 14-10-2018 IPR008217 Ccc1 family Tharo_3251 5e3441451139816a091d4ac4998e3d4c 163 Pfam PF09626 Dihaem cytochrome c 43 160 6.7E-41 T 14-10-2018 IPR018588 Dihaem cytochrome c Tharo_2476 6c88b89df4ced7b616079356b72e8139 163 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 80 161 2.7E-27 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 Tharo_2476 6c88b89df4ced7b616079356b72e8139 163 SUPERFAMILY SSF53155 16 84 4.71E-5 T 14-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 Tharo_2476 6c88b89df4ced7b616079356b72e8139 163 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 79 160 1.3E-24 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 Tharo_2476 6c88b89df4ced7b616079356b72e8139 163 Gene3D G3DSA:1.10.10.10 78 163 5.3E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2476 6c88b89df4ced7b616079356b72e8139 163 SUPERFAMILY SSF46767 78 161 1.44E-24 T 14-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 Tharo_3190 293d6b27f5cfe49efda5a824087efa97 230 Pfam PF01467 Cytidylyltransferase-like 18 202 5.3E-27 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Tharo_3190 293d6b27f5cfe49efda5a824087efa97 230 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 18 229 7.5E-51 T 14-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 Tharo_3190 293d6b27f5cfe49efda5a824087efa97 230 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 14 230 30.175 T 14-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 Tharo_3190 293d6b27f5cfe49efda5a824087efa97 230 Gene3D G3DSA:3.40.50.620 15 230 2.3E-62 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_3190 293d6b27f5cfe49efda5a824087efa97 230 SUPERFAMILY SSF52374 15 230 3.38E-55 T 14-10-2018 Tharo_3190 293d6b27f5cfe49efda5a824087efa97 230 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 17 79 2.3E-11 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Tharo_3307 73051a61838db9c97b74d184b1be35a4 400 ProSitePatterns PS01219 Ammonium transporters signature. 156 181 - T 14-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 Tharo_3307 73051a61838db9c97b74d184b1be35a4 400 Gene3D G3DSA:1.10.3430.10 1 399 2.4E-96 T 14-10-2018 IPR029020 Ammonium/urea transporter Tharo_3307 73051a61838db9c97b74d184b1be35a4 400 Pfam PF00909 Ammonium Transporter Family 12 390 7.5E-86 T 14-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 Tharo_3307 73051a61838db9c97b74d184b1be35a4 400 SUPERFAMILY SSF111352 7 374 3.01E-92 T 14-10-2018 Tharo_1229 aed4393e058df850bd9e6f18e9b562fa 126 SMART SM00422 22 92 1.5E-4 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Tharo_1229 aed4393e058df850bd9e6f18e9b562fa 126 Gene3D G3DSA:1.10.1660.10 16 91 8.4E-21 T 14-10-2018 Tharo_1229 aed4393e058df850bd9e6f18e9b562fa 126 Pfam PF13411 MerR HTH family regulatory protein 22 89 5.3E-21 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Tharo_1229 aed4393e058df850bd9e6f18e9b562fa 126 SUPERFAMILY SSF46955 20 121 2.01E-18 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily Tharo_2056 046ae348ac208e97ea5850d248ca54d9 144 Pfam PF07977 FabA-like domain 10 135 6.9E-42 T 14-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Tharo_2056 046ae348ac208e97ea5850d248ca54d9 144 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 1 140 1.7E-63 T 14-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Tharo_2056 046ae348ac208e97ea5850d248ca54d9 144 Gene3D G3DSA:3.10.129.10 1 144 5.9E-63 T 14-10-2018 Tharo_2056 046ae348ac208e97ea5850d248ca54d9 144 SUPERFAMILY SSF54637 1 140 1.0E-50 T 14-10-2018 IPR029069 HotDog domain superfamily Tharo_2056 046ae348ac208e97ea5850d248ca54d9 144 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 1 143 37.049 T 14-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Tharo_2787 f05dedcb16f7096f33fdbb349f368db7 309 Pfam PF13557 Putative MetA-pathway of phenol degradation 60 305 4.3E-67 T 14-10-2018 IPR025737 MetA-pathway of phenol degradation, putative Tharo_0326 735cbe3586a8d35285007e6c1cd32f10 129 Gene3D G3DSA:3.40.50.510 1 129 1.5E-32 T 14-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 Tharo_0326 735cbe3586a8d35285007e6c1cd32f10 129 SUPERFAMILY SSF53062 1 127 4.58E-30 T 14-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 Tharo_0326 735cbe3586a8d35285007e6c1cd32f10 129 Pfam PF03610 PTS system fructose IIA component 3 107 1.1E-16 T 14-10-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 Tharo_1396 8b900825433d79ab9721a3c395757b27 306 Pfam PF05661 Protein of unknown function (DUF808) 5 290 1.7E-112 T 14-10-2018 IPR008526 Inner membrane protein YedI Tharo_1396 8b900825433d79ab9721a3c395757b27 306 PIRSF PIRSF016660 1 302 5.5E-120 T 14-10-2018 IPR008526 Inner membrane protein YedI Tharo_1049 ff0c9fe8d10a40a3a766df140a0fd787 228 Gene3D G3DSA:3.40.50.2300 1 121 5.3E-37 T 14-10-2018 Tharo_1049 ff0c9fe8d10a40a3a766df140a0fd787 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 217 1.6E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_1049 ff0c9fe8d10a40a3a766df140a0fd787 228 SUPERFAMILY SSF46894 118 218 2.27E-26 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Tharo_1049 ff0c9fe8d10a40a3a766df140a0fd787 228 SUPERFAMILY SSF52172 1 123 2.85E-37 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_1049 ff0c9fe8d10a40a3a766df140a0fd787 228 SMART SM00448 1 112 6.6E-40 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_1049 ff0c9fe8d10a40a3a766df140a0fd787 228 SMART SM00862 144 217 2.2E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Tharo_1049 ff0c9fe8d10a40a3a766df140a0fd787 228 Gene3D G3DSA:1.10.10.10 122 225 1.1E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1049 ff0c9fe8d10a40a3a766df140a0fd787 228 Pfam PF00072 Response regulator receiver domain 3 112 1.3E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_0462 489742e3b8f0ca00843ecec0b0dad23b 159 Pfam PF11749 Protein of unknown function (DUF3305) 5 143 2.7E-48 T 14-10-2018 IPR021736 Protein of unknown function DUF3305 Tharo_0605 69013daa8aa3cfc58b7b600f9e69006d 519 Pfam PF00795 Carbon-nitrogen hydrolase 228 478 5.3E-29 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 Tharo_0605 69013daa8aa3cfc58b7b600f9e69006d 519 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 1 490 22.056 T 14-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 Tharo_0605 69013daa8aa3cfc58b7b600f9e69006d 519 SUPERFAMILY SSF56317 224 483 3.79E-40 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Tharo_0605 69013daa8aa3cfc58b7b600f9e69006d 519 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 55 452 1.4E-86 T 14-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 Tharo_0605 69013daa8aa3cfc58b7b600f9e69006d 519 Gene3D G3DSA:3.60.110.10 224 476 1.0E-15 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Tharo_0972 4788fbb9c0ad17bb8be8f5228adc4fb3 354 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 4 343 4.0E-122 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 Tharo_0972 4788fbb9c0ad17bb8be8f5228adc4fb3 354 Pfam PF02547 Queuosine biosynthesis protein 5 343 4.2E-127 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 Tharo_0972 4788fbb9c0ad17bb8be8f5228adc4fb3 354 SUPERFAMILY SSF111337 4 343 1.06E-127 T 14-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 Tharo_0972 4788fbb9c0ad17bb8be8f5228adc4fb3 354 Gene3D G3DSA:2.40.10.240 69 166 2.0E-108 T 14-10-2018 Tharo_0972 4788fbb9c0ad17bb8be8f5228adc4fb3 354 Gene3D G3DSA:3.40.1780.10 17 342 2.0E-108 T 14-10-2018 Tharo_0972 4788fbb9c0ad17bb8be8f5228adc4fb3 354 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 344 45.168 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 Tharo_3105 59c40b9682d4f201279f989db06f0b4d 446 Pfam PF00909 Ammonium Transporter Family 45 444 4.3E-118 T 14-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 Tharo_3105 59c40b9682d4f201279f989db06f0b4d 446 TIGRFAM TIGR00836 amt: ammonium transporter 43 444 1.2E-130 T 14-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 Tharo_3105 59c40b9682d4f201279f989db06f0b4d 446 PRINTS PR00342 Rhesus blood group protein signature 240 258 9.0E-8 T 14-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 Tharo_3105 59c40b9682d4f201279f989db06f0b4d 446 PRINTS PR00342 Rhesus blood group protein signature 144 160 9.0E-8 T 14-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 Tharo_3105 59c40b9682d4f201279f989db06f0b4d 446 PRINTS PR00342 Rhesus blood group protein signature 326 344 9.0E-8 T 14-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 Tharo_3105 59c40b9682d4f201279f989db06f0b4d 446 PRINTS PR00342 Rhesus blood group protein signature 271 293 9.0E-8 T 14-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 Tharo_3105 59c40b9682d4f201279f989db06f0b4d 446 Gene3D G3DSA:1.10.3430.10 15 446 1.4E-134 T 14-10-2018 IPR029020 Ammonium/urea transporter Tharo_3105 59c40b9682d4f201279f989db06f0b4d 446 ProSitePatterns PS01219 Ammonium transporters signature. 201 226 - T 14-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 Tharo_3105 59c40b9682d4f201279f989db06f0b4d 446 SUPERFAMILY SSF111352 39 425 2.35E-124 T 14-10-2018 Tharo_2933 b3e6cd7387c13aa6a3b1d59161d2b9cd 306 Pfam PF00753 Metallo-beta-lactamase superfamily 16 205 1.1E-21 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_2933 b3e6cd7387c13aa6a3b1d59161d2b9cd 306 Gene3D G3DSA:3.60.15.10 10 230 5.9E-36 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_2933 b3e6cd7387c13aa6a3b1d59161d2b9cd 306 SMART SM00849 20 205 4.2E-25 T 14-10-2018 IPR001279 Metallo-beta-lactamase Tharo_2933 b3e6cd7387c13aa6a3b1d59161d2b9cd 306 SUPERFAMILY SSF56281 17 226 1.32E-40 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Tharo_1320 c9e581c33a1e3899fb86c84b94d5d1a0 83 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 40 1.7E-7 T 14-10-2018 Tharo_1320 c9e581c33a1e3899fb86c84b94d5d1a0 83 Gene3D G3DSA:3.40.1620.10 1 38 1.1E-6 T 14-10-2018 Tharo_1320 c9e581c33a1e3899fb86c84b94d5d1a0 83 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 41 6.3E-10 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Tharo_1320 c9e581c33a1e3899fb86c84b94d5d1a0 83 SUPERFAMILY SSF143120 1 41 6.41E-9 T 14-10-2018 IPR036165 YefM-like superfamily Tharo_3037 bb61bc46bbd4c85036c68dd6b78e618b 157 Pfam PF05232 Chlorhexidine efflux transporter 82 143 1.6E-20 T 14-10-2018 IPR007896 Chlorhexidine efflux transporter Tharo_3037 bb61bc46bbd4c85036c68dd6b78e618b 157 Pfam PF05232 Chlorhexidine efflux transporter 9 72 3.9E-19 T 14-10-2018 IPR007896 Chlorhexidine efflux transporter Tharo_3428 2b137897a23ffbdbc137f1d507aa5dab 87 Pfam PF02796 Helix-turn-helix domain of resolvase 36 76 9.7E-6 T 14-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 Tharo_2153 138a55ef364fd00be1294a429e4451dc 408 Gene3D G3DSA:3.40.50.620 12 279 1.1E-28 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Tharo_2153 138a55ef364fd00be1294a429e4451dc 408 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 38 221 3.1E-9 T 14-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 Tharo_2153 138a55ef364fd00be1294a429e4451dc 408 SUPERFAMILY SSF52402 21 222 1.4E-20 T 14-10-2018 Tharo_3308 2c116be62ba34f28e7d8eea106c6d7b4 190 Gene3D G3DSA:3.40.50.360 4 182 1.5E-44 T 14-10-2018 IPR029039 Flavoprotein-like superfamily Tharo_3308 2c116be62ba34f28e7d8eea106c6d7b4 190 SUPERFAMILY SSF52218 5 175 3.39E-43 T 14-10-2018 IPR029039 Flavoprotein-like superfamily Tharo_3308 2c116be62ba34f28e7d8eea106c6d7b4 190 Pfam PF03358 NADPH-dependent FMN reductase 5 148 9.4E-31 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Tharo_0210 1ca36e097112d118740a388404e17ff7 70 Pfam PF13711 Domain of unknown function (DUF4160) 2 63 1.4E-9 T 14-10-2018 IPR025427 Protein of unknown function DUF4160 Tharo_2555 f2295887f50b1dfa3d9e9d75616ab091 249 Gene3D G3DSA:3.40.50.720 81 228 6.5E-49 T 14-10-2018 Tharo_2555 f2295887f50b1dfa3d9e9d75616ab091 249 Pfam PF13478 XdhC Rossmann domain 82 222 4.6E-41 T 14-10-2018 IPR027051 XdhC Rossmann domain Tharo_2555 f2295887f50b1dfa3d9e9d75616ab091 249 SUPERFAMILY SSF51735 76 177 3.15E-5 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily Tharo_1052 fe6a800cd72e71e89b5bb9f419b78162 85 SUPERFAMILY SSF143120 13 71 4.97E-6 T 14-10-2018 IPR036165 YefM-like superfamily Tharo_1052 fe6a800cd72e71e89b5bb9f419b78162 85 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 12 75 2.5E-7 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Tharo_3424 513026fd3167ecf46020020e4675862d 227 Pfam PF05857 TraX protein 5 216 6.4E-55 T 14-10-2018 IPR008875 TraX Tharo_1197 b21a1f3172ec86470e8d16c84c61094b 251 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 251 100.313 T 14-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 Tharo_1197 b21a1f3172ec86470e8d16c84c61094b 251 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 11 242 5.3E-74 T 14-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 Tharo_1197 b21a1f3172ec86470e8d16c84c61094b 251 SUPERFAMILY SSF56300 12 224 8.46E-24 T 14-10-2018 Tharo_1197 b21a1f3172ec86470e8d16c84c61094b 251 Gene3D G3DSA:3.60.21.10 10 236 9.7E-10 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like Tharo_0082 d8c6169ed85cb0d49d55e04e08f1f29d 899 Gene3D G3DSA:3.40.50.300 641 886 1.0E-12 T 14-10-2018 Tharo_0082 d8c6169ed85cb0d49d55e04e08f1f29d 899 Gene3D G3DSA:3.40.50.300 1 458 2.5E-21 T 14-10-2018 Tharo_0082 d8c6169ed85cb0d49d55e04e08f1f29d 899 SUPERFAMILY SSF52540 1 880 1.28E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0082 d8c6169ed85cb0d49d55e04e08f1f29d 899 Pfam PF13476 AAA domain 5 65 8.2E-12 T 14-10-2018 IPR038729 Rad50/SbcC-type AAA domain Tharo_3295 9db358eda56f41a16f4b5678a821d545 383 Gene3D G3DSA:1.20.1090.10 186 383 1.6E-75 T 14-10-2018 Tharo_3295 9db358eda56f41a16f4b5678a821d545 383 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 14-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 Tharo_3295 9db358eda56f41a16f4b5678a821d545 383 SUPERFAMILY SSF56796 3 381 3.14E-132 T 14-10-2018 Tharo_3295 9db358eda56f41a16f4b5678a821d545 383 Gene3D G3DSA:3.40.50.1970 2 184 8.7E-56 T 14-10-2018 Tharo_3295 9db358eda56f41a16f4b5678a821d545 383 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 260 280 - T 14-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 Tharo_3295 9db358eda56f41a16f4b5678a821d545 383 Pfam PF00465 Iron-containing alcohol dehydrogenase 12 372 1.1E-126 T 14-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 Tharo_2095 4544cd08beff9f448e7db680ea0aeb7c 260 SMART SM01040 12 100 9.3E-42 T 14-10-2018 IPR003497 BRO N-terminal domain Tharo_2095 4544cd08beff9f448e7db680ea0aeb7c 260 Pfam PF02498 BRO family, N-terminal domain 13 100 9.6E-30 T 14-10-2018 IPR003497 BRO N-terminal domain Tharo_0440 c351c46dc545baaab439031d199df45e 285 Pfam PF01728 FtsJ-like methyltransferase 86 271 9.2E-21 T 14-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 Tharo_0440 c351c46dc545baaab439031d199df45e 285 Gene3D G3DSA:3.10.290.10 26 88 2.3E-18 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Tharo_0440 c351c46dc545baaab439031d199df45e 285 Pfam PF01479 S4 domain 29 72 4.5E-10 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_0440 c351c46dc545baaab439031d199df45e 285 PIRSF PIRSF005578 24 283 1.2E-91 T 14-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 Tharo_0440 c351c46dc545baaab439031d199df45e 285 SMART SM00363 29 95 2.0E-9 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_0440 c351c46dc545baaab439031d199df45e 285 SUPERFAMILY SSF55174 29 78 4.27E-10 T 14-10-2018 Tharo_0440 c351c46dc545baaab439031d199df45e 285 SUPERFAMILY SSF53335 86 274 2.74E-21 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_0440 c351c46dc545baaab439031d199df45e 285 Gene3D G3DSA:3.40.50.150 89 283 8.9E-66 T 14-10-2018 Tharo_1901 845c7f2040653640823cf6d8782547b2 316 SUPERFAMILY SSF161098 36 310 3.64E-37 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_1901 845c7f2040653640823cf6d8782547b2 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 313 1.7E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Tharo_1901 845c7f2040653640823cf6d8782547b2 316 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 31 312 6.1E-78 T 14-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 Tharo_1901 845c7f2040653640823cf6d8782547b2 316 Gene3D G3DSA:1.10.3720.10 87 315 8.9E-35 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_0408 4cc5c405bcb44dd14a431318febf08f3 126 Pfam PF06366 Flagellar protein FlhE 31 126 1.2E-21 T 14-10-2018 IPR009420 Flagellar protein FlhE Tharo_3221 bb0cfc963703c98bf1750c387897cd73 609 Pfam PF07715 TonB-dependent Receptor Plug Domain 44 148 1.2E-26 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain Tharo_3221 bb0cfc963703c98bf1750c387897cd73 609 Gene3D G3DSA:2.170.130.10 20 153 2.2E-33 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Tharo_3221 bb0cfc963703c98bf1750c387897cd73 609 SUPERFAMILY SSF56935 29 607 1.69E-115 T 14-10-2018 Tharo_3221 bb0cfc963703c98bf1750c387897cd73 609 Pfam PF00593 TonB dependent receptor 194 607 2.7E-47 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Tharo_3221 bb0cfc963703c98bf1750c387897cd73 609 Gene3D G3DSA:2.40.170.20 157 607 5.9E-109 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Tharo_0619 3c61645b237eb6ac7aca93411bf35b1f 69 Pfam PF00482 Type II secretion system (T2SS), protein F 1 57 6.2E-9 T 14-10-2018 IPR018076 Type II secretion system F domain Tharo_0918 f2d138aacb5f2e562e74d50f1642f01b 588 Pfam PF00905 Penicillin binding protein transpeptidase domain 254 550 3.7E-77 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Tharo_0918 f2d138aacb5f2e562e74d50f1642f01b 588 Gene3D G3DSA:3.40.710.10 290 473 1.0E-111 T 14-10-2018 Tharo_0918 f2d138aacb5f2e562e74d50f1642f01b 588 SUPERFAMILY SSF56601 229 559 2.9E-91 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Tharo_0918 f2d138aacb5f2e562e74d50f1642f01b 588 SUPERFAMILY SSF56519 63 228 4.84E-44 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 Tharo_0918 f2d138aacb5f2e562e74d50f1642f01b 588 Gene3D G3DSA:3.90.1310.30 60 229 9.9E-47 T 14-10-2018 Tharo_0918 f2d138aacb5f2e562e74d50f1642f01b 588 Hamap MF_02080 Peptidoglycan D,D-transpeptidase FtsI [ftsI]. 19 566 42.254 T 14-10-2018 IPR037532 Peptidoglycan D,D-transpeptidase FtsI GO:0005887|GO:0008658|GO:0008955|GO:0009252|GO:0051301 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Tharo_0918 f2d138aacb5f2e562e74d50f1642f01b 588 Gene3D G3DSA:3.30.450.330 230 555 1.0E-111 T 14-10-2018 Tharo_0918 f2d138aacb5f2e562e74d50f1642f01b 588 Pfam PF03717 Penicillin-binding Protein dimerisation domain 67 214 2.5E-21 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 Tharo_1628 37a1479c3197ac8052d0fed93d70f9ee 195 Gene3D G3DSA:1.20.1440.20 15 194 3.9E-60 T 14-10-2018 IPR023353 LemA-like domain superfamily Tharo_1628 37a1479c3197ac8052d0fed93d70f9ee 195 SUPERFAMILY SSF140478 24 181 3.53E-53 T 14-10-2018 IPR023353 LemA-like domain superfamily Tharo_1628 37a1479c3197ac8052d0fed93d70f9ee 195 Pfam PF04011 LemA family 5 194 2.4E-66 T 14-10-2018 IPR007156 LemA Tharo_1772 7e7c1acad24d57a3bf1f4cf0730c4ac6 108 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 3 91 4.1E-16 T 14-10-2018 IPR016772 Uncharacterised conserved protein UCP020408 Tharo_1772 7e7c1acad24d57a3bf1f4cf0730c4ac6 108 PIRSF PIRSF020408 1 105 1.1E-35 T 14-10-2018 IPR016772 Uncharacterised conserved protein UCP020408 Tharo_1770 7c6101f2c273d4b8a53b2c006bbb1a49 554 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 356 544 2.0E-7 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Tharo_1770 7c6101f2c273d4b8a53b2c006bbb1a49 554 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 264 2.0E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Tharo_1770 7c6101f2c273d4b8a53b2c006bbb1a49 554 Gene3D G3DSA:1.10.3720.10 293 552 1.8E-32 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_1770 7c6101f2c273d4b8a53b2c006bbb1a49 554 SUPERFAMILY SSF161098 295 545 1.28E-36 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_1770 7c6101f2c273d4b8a53b2c006bbb1a49 554 Gene3D G3DSA:1.10.3720.10 15 277 2.6E-49 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_1770 7c6101f2c273d4b8a53b2c006bbb1a49 554 SUPERFAMILY SSF161098 16 266 6.21E-40 T 14-10-2018 IPR035906 MetI-like superfamily Tharo_0516 f6d4f56fcdf89ede5f33e4aa582d0144 71 SUPERFAMILY SSF57716 5 61 8.55E-20 T 14-10-2018 Tharo_0516 f6d4f56fcdf89ede5f33e4aa582d0144 71 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 4 61 17.259 T 14-10-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 Tharo_0516 f6d4f56fcdf89ede5f33e4aa582d0144 71 Pfam PF03884 DNA gyrase inhibitor YacG 8 57 5.9E-24 T 14-10-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 Tharo_0516 f6d4f56fcdf89ede5f33e4aa582d0144 71 Gene3D G3DSA:3.30.50.10 1 64 1.4E-22 T 14-10-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 Reactome: R-HSA-383280 Tharo_0948 3b3d3c653b3d8f5243ab381c79d296ad 81 Pfam PF10387 Protein of unknown function (DUF2442) 6 70 1.0E-18 T 14-10-2018 IPR018841 Protein of unknown function DUF2442 Tharo_0948 3b3d3c653b3d8f5243ab381c79d296ad 81 Gene3D G3DSA:3.30.2020.20 2 66 1.9E-14 T 14-10-2018 Tharo_0240 a1132f5b73a1dce39ffd8ccb067647fb 336 SUPERFAMILY SSF56529 76 332 1.96E-58 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Tharo_0240 a1132f5b73a1dce39ffd8ccb067647fb 336 Gene3D G3DSA:3.90.850.10 1 335 2.4E-140 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Tharo_0240 a1132f5b73a1dce39ffd8ccb067647fb 336 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 81 332 8.0E-43 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 Tharo_1493 9fdc63ee908548a37160a1d3ec2bed2c 188 SUPERFAMILY SSF54690 7 152 9.68E-52 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 Tharo_1493 9fdc63ee908548a37160a1d3ec2bed2c 188 Pfam PF02391 MoaE protein 10 123 2.9E-35 T 14-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 Tharo_1493 9fdc63ee908548a37160a1d3ec2bed2c 188 Gene3D G3DSA:3.90.1170.40 3 152 4.0E-50 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 Tharo_0309 a1c375e411b405d232a2665b54e511c2 77 Pfam PF11660 Protein of unknown function (DUF3262) 1 76 1.3E-26 T 14-10-2018 IPR021676 Protein of unknown function DUF3262 Tharo_0309 a1c375e411b405d232a2665b54e511c2 77 TIGRFAM TIGR03758 conj_TIGR03758: integrating conjugative element protein, PFL_4701 family 2 77 1.2E-31 T 14-10-2018 IPR021676 Protein of unknown function DUF3262 Tharo_2035 5b0c8c106fa17ef01a2f4263f4c9bb4f 261 Pfam PF03883 Peroxide stress protein YaaA 1 247 3.9E-89 T 14-10-2018 IPR005583 Peroxide stress protein YaaA Tharo_2035 5b0c8c106fa17ef01a2f4263f4c9bb4f 261 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 259 35.884 T 14-10-2018 IPR005583 Peroxide stress protein YaaA Tharo_0906 55d402df1baed3d1ec88424acda2462b 183 ProSitePatterns PS00194 Thioredoxin family active site. 71 89 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 Tharo_0906 55d402df1baed3d1ec88424acda2462b 183 Pfam PF08534 Redoxin 49 175 4.3E-21 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 Tharo_0906 55d402df1baed3d1ec88424acda2462b 183 SUPERFAMILY SSF52833 3 181 3.67E-34 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_0906 55d402df1baed3d1ec88424acda2462b 183 Gene3D G3DSA:3.40.30.10 35 183 1.0E-36 T 14-10-2018 Tharo_3219 c92c73489d2f8d4ba75beaf273dbb274 267 Pfam PF00005 ABC transporter 32 178 3.3E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Tharo_3219 c92c73489d2f8d4ba75beaf273dbb274 267 Gene3D G3DSA:3.40.50.300 13 261 4.8E-58 T 14-10-2018 Tharo_3219 c92c73489d2f8d4ba75beaf273dbb274 267 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Tharo_3219 c92c73489d2f8d4ba75beaf273dbb274 267 SUPERFAMILY SSF52540 12 241 3.37E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3219 c92c73489d2f8d4ba75beaf273dbb274 267 SMART SM00382 38 228 7.0E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain Tharo_2208 5c5700260364c436643ae975c13a08ea 144 Pfam PF08897 Domain of unknown function (DUF1841) 5 138 6.9E-58 T 14-10-2018 IPR014993 Protein of unknown function DUF1841 Tharo_1347 a46f89eae6e48adc0dedc6c815c65195 276 Hamap MF_01805 Segregation and condensation protein A [scpA]. 41 270 20.951 T 14-10-2018 IPR003768 Segregation and condensation protein A Tharo_1347 a46f89eae6e48adc0dedc6c815c65195 276 Pfam PF02616 Segregation and condensation protein ScpA 58 268 2.6E-27 T 14-10-2018 IPR003768 Segregation and condensation protein A Tharo_1155 0b770d47d889941abe5c1bd27e33ca2c 581 Gene3D G3DSA:3.40.50.1820 233 512 6.0E-9 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_1155 0b770d47d889941abe5c1bd27e33ca2c 581 TIGRFAM TIGR01838 PHA_synth_I: poly(R)-hydroxyalkanoic acid synthase, class I 54 579 3.4E-209 T 14-10-2018 IPR010963 Poly(R)-hydroxyalkanoic acid synthase, class I GO:0005737|GO:0016746|GO:0042619 Tharo_1155 0b770d47d889941abe5c1bd27e33ca2c 581 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 94 261 7.3E-68 T 14-10-2018 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 Tharo_1155 0b770d47d889941abe5c1bd27e33ca2c 581 SUPERFAMILY SSF53474 219 503 2.14E-34 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_2525 a3d743b9b58c3f92ed99e51614d55def 124 SMART SM00448 3 116 7.8E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2525 a3d743b9b58c3f92ed99e51614d55def 124 SUPERFAMILY SSF52172 3 121 4.55E-37 T 14-10-2018 IPR011006 CheY-like superfamily Tharo_2525 a3d743b9b58c3f92ed99e51614d55def 124 Gene3D G3DSA:3.40.50.12740 1 123 1.2E-43 T 14-10-2018 Tharo_2525 a3d743b9b58c3f92ed99e51614d55def 124 Pfam PF00072 Response regulator receiver domain 5 113 3.6E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Tharo_2786 6a5e163d7c443e959a975a7f6360c605 433 Pfam PF14535 AMP-binding enzyme C-terminal domain 342 427 5.8E-15 T 14-10-2018 IPR028154 AMP-dependent ligase, C-terminal Tharo_2786 6a5e163d7c443e959a975a7f6360c605 433 Gene3D G3DSA:3.30.300.30 334 432 9.3E-22 T 14-10-2018 Tharo_2786 6a5e163d7c443e959a975a7f6360c605 433 SUPERFAMILY SSF56801 29 375 1.83E-46 T 14-10-2018 Tharo_2786 6a5e163d7c443e959a975a7f6360c605 433 Pfam PF00501 AMP-binding enzyme 96 292 1.3E-8 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Tharo_2786 6a5e163d7c443e959a975a7f6360c605 433 Gene3D G3DSA:3.40.50.12780 2 333 2.0E-100 T 14-10-2018 Tharo_3112 89a01616dc5f625973cc76b5c44e9fd6 271 Pfam PF01936 NYN domain 17 150 9.3E-30 T 14-10-2018 IPR021139 NYN domain, limkain-b1-type Tharo_3112 89a01616dc5f625973cc76b5c44e9fd6 271 Pfam PF12872 OST-HTH/LOTUS domain 195 253 2.8E-14 T 14-10-2018 IPR025605 OST-HTH/LOTUS domain Tharo_3112 89a01616dc5f625973cc76b5c44e9fd6 271 Gene3D G3DSA:1.10.10.1880 195 268 9.0E-27 T 14-10-2018 Tharo_3112 89a01616dc5f625973cc76b5c44e9fd6 271 Gene3D G3DSA:3.40.50.1010 8 154 3.4E-13 T 14-10-2018 Tharo_1745 8cb1b230f6745f7a2aba878f3a46e86b 289 Pfam PF09459 Ethylbenzene dehydrogenase 24 271 6.9E-50 T 14-10-2018 IPR019020 Cytochrome c-552/DMSO reductase-like, haem-binding domain GO:0020037 Tharo_1745 8cb1b230f6745f7a2aba878f3a46e86b 289 Gene3D G3DSA:2.60.40.1190 166 274 1.1E-7 T 14-10-2018 Tharo_1745 8cb1b230f6745f7a2aba878f3a46e86b 289 SMART SM00887 24 271 6.9E-83 T 14-10-2018 IPR019020 Cytochrome c-552/DMSO reductase-like, haem-binding domain GO:0020037 Tharo_2110 ae4ab472b96dee780723821b49d2d634 337 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 72 265 3.7E-16 T 14-10-2018 IPR000477 Reverse transcriptase domain Tharo_2110 ae4ab472b96dee780723821b49d2d634 337 SUPERFAMILY SSF56672 40 287 1.21E-26 T 14-10-2018 Tharo_0829 619be01adb51358adb7a7300b9d51060 360 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 359 73.512 T 14-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 Tharo_0829 619be01adb51358adb7a7300b9d51060 360 PIRSF PIRSF001455 4 359 2.6E-106 T 14-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 Tharo_0829 619be01adb51358adb7a7300b9d51060 360 Gene3D G3DSA:3.40.50.1970 1 172 5.9E-67 T 14-10-2018 Tharo_0829 619be01adb51358adb7a7300b9d51060 360 SUPERFAMILY SSF56796 4 356 2.22E-120 T 14-10-2018 Tharo_0829 619be01adb51358adb7a7300b9d51060 360 Pfam PF01761 3-dehydroquinate synthase 67 324 7.4E-108 T 14-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 Tharo_0829 619be01adb51358adb7a7300b9d51060 360 Gene3D G3DSA:1.20.1090.10 173 359 2.1E-63 T 14-10-2018 Tharo_0829 619be01adb51358adb7a7300b9d51060 360 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 347 3.4E-116 T 14-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 Tharo_2509 d994d5b17817559e3736a634171b3e05 117 Pfam PF09842 Predicted membrane protein (DUF2069) 10 108 1.6E-31 T 14-10-2018 IPR018643 Protein of unknown function DUF2069, membrane Tharo_0269 2700466032c3777d6fb61300544b9f30 406 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 4 122 5.8E-26 T 14-10-2018 IPR017560 Cytochrome c-type biogenesis protein CcmI Tharo_0269 2700466032c3777d6fb61300544b9f30 406 SUPERFAMILY SSF48452 146 255 1.3E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_0269 2700466032c3777d6fb61300544b9f30 406 Gene3D G3DSA:1.25.40.10 142 280 1.8E-23 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_0169 9590e44b5cf92f899b86b0f5e44d91a0 311 Pfam PF05853 beta-keto acid cleavage enzyme 7 303 3.8E-105 T 14-10-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247 Tharo_0169 9590e44b5cf92f899b86b0f5e44d91a0 311 Gene3D G3DSA:3.20.20.70 2 311 1.3E-122 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_1501 5963b363bb20594eb403f7f534d37b1f 164 Pfam PF03734 L,D-transpeptidase catalytic domain 7 162 1.9E-17 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 Tharo_1501 5963b363bb20594eb403f7f534d37b1f 164 SUPERFAMILY SSF141523 4 162 1.57E-23 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like Tharo_1501 5963b363bb20594eb403f7f534d37b1f 164 Gene3D G3DSA:2.40.440.10 2 164 1.0E-29 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like Tharo_0171 e5a717736ea13e5a2a880fd3f834eb94 569 Pfam PF06980 Protein of unknown function (DUF1302) 39 569 2.2E-113 T 14-10-2018 IPR010727 Protein of unknown function DUF1302 Tharo_0244 8274ea11ced242be867a0bd25411bec3 344 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 33 314 6.7E-51 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 Tharo_0244 8274ea11ced242be867a0bd25411bec3 344 SUPERFAMILY SSF53850 128 241 4.07E-5 T 14-10-2018 Tharo_0244 8274ea11ced242be867a0bd25411bec3 344 Gene3D G3DSA:3.40.190.170 29 343 1.9E-91 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily Tharo_2566 f19ed01bfbccc946ab518b5d6d400281 186 SUPERFAMILY SSF101874 26 183 1.24E-39 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily Tharo_2566 f19ed01bfbccc946ab518b5d6d400281 186 SMART SM00867 22 183 1.2E-40 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Tharo_2566 f19ed01bfbccc946ab518b5d6d400281 186 Pfam PF04264 YceI-like domain 26 182 2.1E-30 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Tharo_2566 f19ed01bfbccc946ab518b5d6d400281 186 Gene3D G3DSA:2.40.128.110 25 185 4.9E-38 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily Tharo_1367 ba0fa38f771a3a341ed796d5e30160ff 1221 Pfam PF05359 Domain of Unknown Function (DUF748) 590 743 4.7E-30 T 14-10-2018 IPR008023 Protein of unknown function DUF748 Tharo_1367 ba0fa38f771a3a341ed796d5e30160ff 1221 Pfam PF05359 Domain of Unknown Function (DUF748) 367 518 4.0E-24 T 14-10-2018 IPR008023 Protein of unknown function DUF748 Tharo_1367 ba0fa38f771a3a341ed796d5e30160ff 1221 Pfam PF05359 Domain of Unknown Function (DUF748) 831 977 4.4E-37 T 14-10-2018 IPR008023 Protein of unknown function DUF748 Tharo_1367 ba0fa38f771a3a341ed796d5e30160ff 1221 Pfam PF05359 Domain of Unknown Function (DUF748) 133 280 7.6E-19 T 14-10-2018 IPR008023 Protein of unknown function DUF748 Tharo_0899 9615fd64793cbdb60dde73f4747500d7 259 SUPERFAMILY SSF55729 27 230 1.65E-44 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Tharo_0899 9615fd64793cbdb60dde73f4747500d7 259 Pfam PF13444 Acetyltransferase (GNAT) domain 40 141 1.0E-33 T 14-10-2018 Tharo_0899 9615fd64793cbdb60dde73f4747500d7 259 Gene3D G3DSA:3.40.630.30 30 171 1.6E-27 T 14-10-2018 Tharo_0058 133d7b7cdad6894e8367767776150459 156 Hamap MF_00598 Protein Smg [smg]. 1 156 26.984 T 14-10-2018 IPR007456 Smg Tharo_0058 133d7b7cdad6894e8367767776150459 156 Pfam PF04361 Protein of unknown function (DUF494) 1 148 6.8E-54 T 14-10-2018 IPR007456 Smg Tharo_3398 5fe578ed3e53696c59c964e3237ca913 339 SUPERFAMILY SSF116734 124 330 5.23E-26 T 14-10-2018 Tharo_3398 5fe578ed3e53696c59c964e3237ca913 339 Gene3D G3DSA:3.90.220.20 1 96 1.9E-18 T 14-10-2018 Tharo_3398 5fe578ed3e53696c59c964e3237ca913 339 Gene3D G3DSA:3.90.220.20 126 325 3.9E-20 T 14-10-2018 Tharo_3398 5fe578ed3e53696c59c964e3237ca913 339 SUPERFAMILY SSF116734 2 101 6.05E-21 T 14-10-2018 Tharo_3398 5fe578ed3e53696c59c964e3237ca913 339 Pfam PF01420 Type I restriction modification DNA specificity domain 14 84 2.3E-8 T 14-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 Tharo_3398 5fe578ed3e53696c59c964e3237ca913 339 Pfam PF01420 Type I restriction modification DNA specificity domain 139 301 1.5E-5 T 14-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 Tharo_3391 6002024a5d8e3e67a3642204b2fbdafb 200 Pfam PF14334 Domain of unknown function (DUF4390) 35 190 3.2E-57 T 14-10-2018 IPR025500 Protein of unknown function DUF4390 Tharo_2381 29c606c9fa55ab86a156552b2ae38c49 560 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 14 524 2.5E-111 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit Tharo_0262 22ad5678e25f8e1285d6f41ce2a93774 222 PIRSF PIRSF002764 1 222 1.5E-74 T 14-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria Tharo_0262 22ad5678e25f8e1285d6f41ce2a93774 222 Pfam PF03379 CcmB protein 6 219 6.0E-70 T 14-10-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 Tharo_0262 22ad5678e25f8e1285d6f41ce2a93774 222 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 8 218 4.1E-69 T 14-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria Tharo_0262 22ad5678e25f8e1285d6f41ce2a93774 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 78 101 1.1E-60 T 14-10-2018 Tharo_0262 22ad5678e25f8e1285d6f41ce2a93774 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 29 50 1.1E-60 T 14-10-2018 Tharo_0262 22ad5678e25f8e1285d6f41ce2a93774 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 55 72 1.1E-60 T 14-10-2018 Tharo_0262 22ad5678e25f8e1285d6f41ce2a93774 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 134 157 1.1E-60 T 14-10-2018 Tharo_0262 22ad5678e25f8e1285d6f41ce2a93774 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 195 218 1.1E-60 T 14-10-2018 Tharo_0262 22ad5678e25f8e1285d6f41ce2a93774 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 157 176 1.1E-60 T 14-10-2018 Tharo_0262 22ad5678e25f8e1285d6f41ce2a93774 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 103 121 1.1E-60 T 14-10-2018 Tharo_3008 027920bf133db4b034e5096c8f23c4f7 74 Pfam PF10932 Protein of unknown function (DUF2783) 3 72 1.2E-30 T 14-10-2018 IPR021233 Protein of unknown function DUF2783 Tharo_1086 b7f78f480736e7ea72a40a08128d01e8 299 Gene3D G3DSA:3.20.20.70 50 292 1.1E-14 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_1086 b7f78f480736e7ea72a40a08128d01e8 299 SUPERFAMILY SSF102114 52 253 5.1E-13 T 14-10-2018 Tharo_2288 a37c473a77aa307349ec9876b762c2cd 126 Pfam PF04247 Invasion gene expression up-regulator, SirB 2 120 1.7E-44 T 14-10-2018 IPR007360 Invasion gene expression up-regulator, SirB Tharo_2288 a37c473a77aa307349ec9876b762c2cd 126 PIRSF PIRSF005610 1 119 1.4E-26 T 14-10-2018 IPR007360 Invasion gene expression up-regulator, SirB Tharo_2962 d080b07b1af4d6c0dd1eee9eac7a23fe 177 Gene3D G3DSA:3.30.1050.10 92 163 1.2E-6 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily Tharo_2962 d080b07b1af4d6c0dd1eee9eac7a23fe 177 Pfam PF02036 SCP-2 sterol transfer family 73 159 2.0E-15 T 14-10-2018 IPR003033 SCP2 sterol-binding domain Tharo_2962 d080b07b1af4d6c0dd1eee9eac7a23fe 177 SUPERFAMILY SSF55718 73 166 2.59E-18 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily Tharo_2657 e50fec0c723d3ffd72b27c1cf40d24a8 407 Gene3D G3DSA:1.10.150.130 101 204 4.6E-30 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal Tharo_2657 e50fec0c723d3ffd72b27c1cf40d24a8 407 Pfam PF13356 Arm DNA-binding domain 3 87 1.0E-19 T 14-10-2018 IPR025166 Integrase, DNA-binding domain Tharo_2657 e50fec0c723d3ffd72b27c1cf40d24a8 407 Pfam PF00589 Phage integrase family 212 372 1.1E-17 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Tharo_2657 e50fec0c723d3ffd72b27c1cf40d24a8 407 SUPERFAMILY SSF56349 100 384 1.72E-59 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Tharo_2657 e50fec0c723d3ffd72b27c1cf40d24a8 407 Gene3D G3DSA:1.10.443.10 205 389 2.7E-16 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Tharo_2657 e50fec0c723d3ffd72b27c1cf40d24a8 407 Gene3D G3DSA:3.30.160.390 1 100 4.4E-37 T 14-10-2018 IPR038488 Integrase, DNA-binding domain superfamily Tharo_0011 6a2952e2cd64db6883ffc038f6ae8573 87 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 24 86 4.9E-10 T 14-10-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 Tharo_0011 6a2952e2cd64db6883ffc038f6ae8573 87 SUPERFAMILY SSF143011 2 87 2.09E-19 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_0011 6a2952e2cd64db6883ffc038f6ae8573 87 Gene3D G3DSA:3.30.2310.20 2 86 5.4E-13 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_0011 6a2952e2cd64db6883ffc038f6ae8573 87 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 7 86 6.0E-28 T 14-10-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 Tharo_0360 26d4140c5e721c08e701d3dc4978377a 133 Gene3D G3DSA:3.40.50.1010 1 130 5.5E-39 T 14-10-2018 Tharo_0360 26d4140c5e721c08e701d3dc4978377a 133 Pfam PF01850 PIN domain 4 123 8.4E-16 T 14-10-2018 IPR002716 PIN domain Tharo_0360 26d4140c5e721c08e701d3dc4978377a 133 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 128 12.555 T 14-10-2018 IPR022907 VapC family GO:0004540 Tharo_0360 26d4140c5e721c08e701d3dc4978377a 133 SUPERFAMILY SSF88723 1 130 1.12E-33 T 14-10-2018 IPR029060 PIN-like domain superfamily Tharo_0735 a44c6e707b012fb11417398853766c4c 125 Pfam PF11358 Protein of unknown function (DUF3158) 1 115 5.5E-54 T 14-10-2018 IPR021502 Protein of unknown function DUF3158 Tharo_1715 4a23cd90b66ea25f17133f2aad84228c 681 Gene3D G3DSA:1.20.1730.10 350 665 4.2E-27 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily Tharo_1715 4a23cd90b66ea25f17133f2aad84228c 681 Gene3D G3DSA:1.20.1730.10 59 273 5.0E-35 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily Tharo_1715 4a23cd90b66ea25f17133f2aad84228c 681 Pfam PF00474 Sodium:solute symporter family 489 604 6.4E-23 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 Tharo_1715 4a23cd90b66ea25f17133f2aad84228c 681 Pfam PF00474 Sodium:solute symporter family 69 238 1.2E-32 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 Tharo_1715 4a23cd90b66ea25f17133f2aad84228c 681 TIGRFAM TIGR03648 Na_symport_lg: probable sodium:solute symporter, VC_2705 subfamily 45 671 9.1E-235 T 14-10-2018 IPR019899 Sodium/solute symporter, VC2705 subfamily Tharo_1715 4a23cd90b66ea25f17133f2aad84228c 681 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 586 606 - T 14-10-2018 IPR018212 Sodium/solute symporter, conserved site Tharo_2800 bebb180b138b5205cb15809455a34e8b 238 SUPERFAMILY SSF54001 76 204 1.07E-7 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily Tharo_2800 bebb180b138b5205cb15809455a34e8b 238 Gene3D G3DSA:3.10.620.30 40 238 1.2E-71 T 14-10-2018 Tharo_2800 bebb180b138b5205cb15809455a34e8b 238 Pfam PF06035 Bacterial transglutaminase-like cysteine proteinase BTLCP 73 188 1.4E-13 T 14-10-2018 IPR010319 Transglutaminase-like cysteine peptidase, predicted Tharo_1111 eaabba9987b76d4331ac5694c61a9866 185 Gene3D G3DSA:1.20.120.520 4 176 2.8E-26 T 14-10-2018 Tharo_1111 eaabba9987b76d4331ac5694c61a9866 185 Pfam PF01814 Hemerythrin HHE cation binding domain 14 153 8.4E-13 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 Tharo_2339 92455104f70e3640aa28747ef8eee2c2 194 Pfam PF12007 Protein of unknown function (DUF3501) 3 192 8.3E-71 T 14-10-2018 IPR021890 Protein of unknown function DUF3501 Tharo_1437 affa00b4aad57174481b3c4dbc5f4036 263 SUPERFAMILY SSF54534 100 210 4.06E-18 T 14-10-2018 Tharo_1437 affa00b4aad57174481b3c4dbc5f4036 263 Gene3D G3DSA:1.10.4030.30 83 210 5.6E-17 T 14-10-2018 Tharo_1437 affa00b4aad57174481b3c4dbc5f4036 263 Pfam PF00639 PPIC-type PPIASE domain 110 205 1.1E-13 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 Tharo_1437 affa00b4aad57174481b3c4dbc5f4036 263 Gene3D G3DSA:3.10.50.40 104 209 5.6E-17 T 14-10-2018 Tharo_0459 5f87d8f6be166d162afb9deee5052a87 163 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 3 135 2.6E-51 T 14-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 Tharo_0459 5f87d8f6be166d162afb9deee5052a87 163 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 3 158 1.7E-48 T 14-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 Tharo_0459 5f87d8f6be166d162afb9deee5052a87 163 SUPERFAMILY SSF52540 1 160 8.83E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0459 5f87d8f6be166d162afb9deee5052a87 163 Gene3D G3DSA:3.40.50.300 4 157 6.3E-60 T 14-10-2018 Tharo_0459 5f87d8f6be166d162afb9deee5052a87 163 Gene3D G3DSA:2.20.25.120 47 79 6.3E-60 T 14-10-2018 Tharo_1737 e1a314604f147e86036ddfe8210ba2ce 110 Gene3D G3DSA:3.10.20.280 1 92 7.6E-33 T 14-10-2018 IPR037021 RnfH superfamily Tharo_1737 e1a314604f147e86036ddfe8210ba2ce 110 SUPERFAMILY SSF54285 6 82 1.31E-24 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp Tharo_1737 e1a314604f147e86036ddfe8210ba2ce 110 Hamap MF_00460 Protein RnfH [rnfH]. 7 98 25.706 T 14-10-2018 IPR005346 RnfH protein Tharo_1737 e1a314604f147e86036ddfe8210ba2ce 110 Pfam PF03658 RnfH family Ubiquitin 7 90 1.0E-34 T 14-10-2018 IPR005346 RnfH protein Tharo_0615 8e8c160d57623b23678df7e00683da74 214 SUPERFAMILY SSF54523 8 104 4.63E-10 T 14-10-2018 Tharo_0615 8e8c160d57623b23678df7e00683da74 214 Pfam PF07963 Prokaryotic N-terminal methylation motif 4 28 4.7E-7 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Tharo_0615 8e8c160d57623b23678df7e00683da74 214 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 28 1.4E-5 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Tharo_0615 8e8c160d57623b23678df7e00683da74 214 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Tharo_3378 ff8578cfde3f098b516fdd5b8d62d9cd 375 SUPERFAMILY SSF55874 199 367 9.56E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_3378 ff8578cfde3f098b516fdd5b8d62d9cd 375 SUPERFAMILY SSF47384 128 209 6.67E-18 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Tharo_3378 ff8578cfde3f098b516fdd5b8d62d9cd 375 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 255 366 9.3E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_3378 ff8578cfde3f098b516fdd5b8d62d9cd 375 SMART SM00387 255 369 4.1E-33 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Tharo_3378 ff8578cfde3f098b516fdd5b8d62d9cd 375 SMART SM00388 145 210 2.1E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_3378 ff8578cfde3f098b516fdd5b8d62d9cd 375 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 366 6.6E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3378 ff8578cfde3f098b516fdd5b8d62d9cd 375 PRINTS PR00344 Bacterial sensor protein C-terminal signature 314 324 6.6E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3378 ff8578cfde3f098b516fdd5b8d62d9cd 375 PRINTS PR00344 Bacterial sensor protein C-terminal signature 296 310 6.6E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3378 ff8578cfde3f098b516fdd5b8d62d9cd 375 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 346 6.6E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Tharo_3378 ff8578cfde3f098b516fdd5b8d62d9cd 375 Gene3D G3DSA:3.30.565.10 213 367 2.0E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Tharo_3378 ff8578cfde3f098b516fdd5b8d62d9cd 375 Gene3D G3DSA:1.10.287.130 96 211 1.3E-20 T 14-10-2018 Tharo_3378 ff8578cfde3f098b516fdd5b8d62d9cd 375 Pfam PF00512 His Kinase A (phospho-acceptor) domain 147 208 9.5E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Tharo_3413 29a2a374065c6c9f019074cf724b30e6 257 Gene3D G3DSA:3.10.450.230 139 255 1.2E-8 T 14-10-2018 Tharo_3413 29a2a374065c6c9f019074cf724b30e6 257 SUPERFAMILY SSF54427 114 255 4.34E-26 T 14-10-2018 IPR032710 NTF2-like domain superfamily Tharo_3413 29a2a374065c6c9f019074cf724b30e6 257 Pfam PF04335 VirB8 protein 44 255 2.8E-58 T 14-10-2018 IPR007430 Bacterial virulence protein VirB8 GO:0016020 Tharo_3461 9281797caea60ecaee7634d41d175815 254 PIRSF PIRSF009320 1 107 5.0E-12 T 14-10-2018 Tharo_3461 9281797caea60ecaee7634d41d175815 254 PIRSF PIRSF009320 99 254 1.5E-8 T 14-10-2018 Tharo_3461 9281797caea60ecaee7634d41d175815 254 SUPERFAMILY SSF52540 1 251 1.29E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_3461 9281797caea60ecaee7634d41d175815 254 Gene3D G3DSA:3.40.50.300 1 254 5.5E-52 T 14-10-2018 Tharo_3461 9281797caea60ecaee7634d41d175815 254 Pfam PF13614 AAA domain 1 172 2.1E-28 T 14-10-2018 IPR025669 AAA domain Tharo_2575 a283a0ec4297df665618e22ee6280d45 438 SUPERFAMILY SSF53448 3 243 3.52E-49 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_2575 a283a0ec4297df665618e22ee6280d45 438 Pfam PF00535 Glycosyl transferase family 2 7 173 4.5E-25 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Tharo_2575 a283a0ec4297df665618e22ee6280d45 438 Gene3D G3DSA:3.90.550.10 1 231 1.2E-44 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Tharo_3438 05389f29e3a25048256efde8c2757bd8 115 Gene3D G3DSA:1.10.3730.20 1 106 2.0E-34 T 14-10-2018 Tharo_3438 05389f29e3a25048256efde8c2757bd8 115 Pfam PF00893 Small Multidrug Resistance protein 3 94 7.1E-32 T 14-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 Tharo_3438 05389f29e3a25048256efde8c2757bd8 115 SUPERFAMILY SSF103481 5 107 1.44E-19 T 14-10-2018 Tharo_0709 165aa4dcb26163d2a836f12994849d57 187 Gene3D G3DSA:1.10.530.10 22 178 4.3E-9 T 14-10-2018 Tharo_0709 165aa4dcb26163d2a836f12994849d57 187 Pfam PF01464 Transglycosylase SLT domain 27 148 7.5E-7 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 Tharo_0709 165aa4dcb26163d2a836f12994849d57 187 SUPERFAMILY SSF53955 24 168 1.58E-15 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily Tharo_2624 db77b185ad406772e67b8f6c5dd102cf 587 Gene3D G3DSA:1.20.1530.20 12 400 5.0E-17 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily Tharo_2624 db77b185ad406772e67b8f6c5dd102cf 587 SUPERFAMILY SSF116726 420 493 5.89E-5 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Tharo_2624 db77b185ad406772e67b8f6c5dd102cf 587 SMART SM01091 502 582 5.8E-4 T 14-10-2018 IPR005170 Transporter-associated domain Tharo_2624 db77b185ad406772e67b8f6c5dd102cf 587 Pfam PF00999 Sodium/hydrogen exchanger family 20 395 1.9E-46 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Tharo_0933 98412115ff180b4532ec1b5891b93384 120 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 5 108 3.6E-22 T 14-10-2018 IPR019277 Protein of unknown function DUF2304 Tharo_2008 1503a6af0a46de49b62759ab6ed553fb 60 Pfam PF16762 Ribbon-helix-helix domain 1 58 7.5E-27 T 14-10-2018 IPR031914 XACb0070, ribbon-helix-helix domain Tharo_2008 1503a6af0a46de49b62759ab6ed553fb 60 Gene3D G3DSA:1.10.1220.10 1 32 2.0E-16 T 14-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 Tharo_0449 3ec9a80ca646353d7043f0aa18c662ac 311 SUPERFAMILY SSF53807 26 291 2.0E-65 T 14-10-2018 Tharo_0449 3ec9a80ca646353d7043f0aa18c662ac 311 Pfam PF01497 Periplasmic binding protein 48 271 7.5E-29 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain Tharo_0449 3ec9a80ca646353d7043f0aa18c662ac 311 Gene3D G3DSA:3.40.50.1980 166 296 2.7E-30 T 14-10-2018 Tharo_0449 3ec9a80ca646353d7043f0aa18c662ac 311 Gene3D G3DSA:3.40.50.1980 44 162 1.3E-38 T 14-10-2018 Tharo_3230 e723332f77e8ac7b59b9495bd366af2d 85 SUPERFAMILY SSF143011 2 83 9.29E-19 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_3230 e723332f77e8ac7b59b9495bd366af2d 85 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 2 84 1.6E-8 T 14-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Tharo_3230 e723332f77e8ac7b59b9495bd366af2d 85 Gene3D G3DSA:3.30.2310.20 1 85 1.9E-25 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_0765 9cf6033a13d4a38c3c5630c3d4089607 137 Gene3D G3DSA:3.30.160.250 18 100 1.1E-15 T 14-10-2018 Tharo_0765 9cf6033a13d4a38c3c5630c3d4089607 137 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 27 126 9.1E-11 T 14-10-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system Tharo_0765 9cf6033a13d4a38c3c5630c3d4089607 137 SUPERFAMILY SSF143100 22 80 1.18E-14 T 14-10-2018 IPR035069 TTHA1013/TTHA0281-like Tharo_0765 9cf6033a13d4a38c3c5630c3d4089607 137 SUPERFAMILY SSF47598 92 134 6.67E-8 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Tharo_2762 0abad97411cb56a10fb5ce6d5bc464ce 63 Pfam PF04964 Flp/Fap pilin component 13 57 6.2E-12 T 14-10-2018 IPR007047 Flp/Fap pilin component Tharo_1098 50ec6d7f018e222b3db5d414d737b160 370 Gene3D G3DSA:3.10.310.10 11 358 3.3E-112 T 14-10-2018 Tharo_1098 50ec6d7f018e222b3db5d414d737b160 370 SUPERFAMILY SSF54506 178 364 2.51E-55 T 14-10-2018 Tharo_1098 50ec6d7f018e222b3db5d414d737b160 370 Pfam PF04303 PrpF protein 10 360 1.1E-112 T 14-10-2018 IPR007400 PrpF protein Tharo_1098 50ec6d7f018e222b3db5d414d737b160 370 SUPERFAMILY SSF54506 7 174 7.46E-62 T 14-10-2018 Tharo_1098 50ec6d7f018e222b3db5d414d737b160 370 Gene3D G3DSA:3.10.310.10 173 344 3.3E-112 T 14-10-2018 Tharo_0392 320d21e5fb3c88bbc4055c796774c938 103 Gene3D G3DSA:3.40.1690.10 8 87 1.9E-21 T 14-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal Tharo_0392 320d21e5fb3c88bbc4055c796774c938 103 SUPERFAMILY SSF160544 9 85 1.96E-20 T 14-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal Tharo_0392 320d21e5fb3c88bbc4055c796774c938 103 Pfam PF01312 FlhB HrpN YscU SpaS Family 11 82 4.2E-16 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 Tharo_1889 859b3c2229aa00e2eefd2714a3fd6d0d 136 Pfam PF04355 SmpA / OmlA family 37 102 4.3E-26 T 14-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 Tharo_1889 859b3c2229aa00e2eefd2714a3fd6d0d 136 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 1 117 27.721 T 14-10-2018 IPR026592 Outer membrane protein assembly factor BamE Tharo_1889 859b3c2229aa00e2eefd2714a3fd6d0d 136 Gene3D G3DSA:3.30.1450.10 36 117 8.4E-28 T 14-10-2018 IPR037873 BamE-like Tharo_1476 e11e582ca5ef706947e0c3936513626c 335 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 53 243 5.4E-10 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 Tharo_1476 e11e582ca5ef706947e0c3936513626c 335 PIRSF PIRSF015582 21 324 3.3E-44 T 14-10-2018 IPR011206 Citrate lyase beta subunit-like Tharo_1476 e11e582ca5ef706947e0c3936513626c 335 SUPERFAMILY SSF51621 30 264 1.38E-37 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Tharo_1476 e11e582ca5ef706947e0c3936513626c 335 Gene3D G3DSA:3.20.20.60 1 268 4.3E-103 T 14-10-2018 Tharo_0872 86592ebc63d3213a3833f80447d8e80a 89 PIRSF PIRSF028784 1 89 6.6E-26 T 14-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 Tharo_0872 86592ebc63d3213a3833f80447d8e80a 89 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 32 82 1.3E-19 T 14-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 Tharo_2828 66985d9a07a22a6a8c386eaaac383a91 237 SUPERFAMILY SSF46785 110 189 1.09E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_2828 66985d9a07a22a6a8c386eaaac383a91 237 SUPERFAMILY SSF46785 24 104 1.02E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_2828 66985d9a07a22a6a8c386eaaac383a91 237 Gene3D G3DSA:1.10.10.10 112 191 3.8E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2828 66985d9a07a22a6a8c386eaaac383a91 237 Gene3D G3DSA:1.10.10.10 7 111 3.6E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_2828 66985d9a07a22a6a8c386eaaac383a91 237 Pfam PF04337 Protein of unknown function, DUF480 26 173 2.2E-60 T 14-10-2018 IPR007432 Protein of unknown function DUF480 Tharo_2828 66985d9a07a22a6a8c386eaaac383a91 237 Hamap MF_01584 UPF0502 protein YceH [yceH]. 26 234 31.074 T 14-10-2018 IPR007432 Protein of unknown function DUF480 Tharo_2079 1a3beba70c48a3ed8d28e3428c1d9b2b 382 Pfam PF07687 Peptidase dimerisation domain 179 286 2.6E-24 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain Tharo_2079 1a3beba70c48a3ed8d28e3428c1d9b2b 382 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 6 379 52.526 T 14-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 Tharo_2079 1a3beba70c48a3ed8d28e3428c1d9b2b 382 SUPERFAMILY SSF55031 183 292 7.92E-30 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain Tharo_2079 1a3beba70c48a3ed8d28e3428c1d9b2b 382 Gene3D G3DSA:3.30.70.360 183 296 3.3E-130 T 14-10-2018 Tharo_2079 1a3beba70c48a3ed8d28e3428c1d9b2b 382 Gene3D G3DSA:3.40.630.10 11 365 3.3E-130 T 14-10-2018 Tharo_2079 1a3beba70c48a3ed8d28e3428c1d9b2b 382 SUPERFAMILY SSF53187 8 378 2.4E-64 T 14-10-2018 Tharo_2079 1a3beba70c48a3ed8d28e3428c1d9b2b 382 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 9 376 9.9E-164 T 14-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 Tharo_2079 1a3beba70c48a3ed8d28e3428c1d9b2b 382 Pfam PF01546 Peptidase family M20/M25/M40 66 375 4.7E-42 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 Tharo_1114 27b82dedddc80c46fca07cbe6490cff2 236 Gene3D G3DSA:3.90.850.10 3 235 4.3E-77 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Tharo_1114 27b82dedddc80c46fca07cbe6490cff2 236 SUPERFAMILY SSF56529 23 233 4.58E-63 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Tharo_1114 27b82dedddc80c46fca07cbe6490cff2 236 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 29 229 1.5E-48 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 Tharo_3147 7ea50389dadf35b48fe1f5ca4b828b36 547 Pfam PF01435 Peptidase family M48 85 337 5.3E-21 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 Tharo_0264 ac6999ea4a70dd5cdc7020bb2231c009 75 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 10 54 4.5E-14 T 14-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 Tharo_0264 ac6999ea4a70dd5cdc7020bb2231c009 75 Pfam PF04995 Heme exporter protein D (CcmD) 16 50 6.5E-8 T 14-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 Tharo_2240 5b209b5862f848fa8e976445681a08d8 222 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 28 2.1E-4 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Tharo_2240 5b209b5862f848fa8e976445681a08d8 222 Pfam PF07963 Prokaryotic N-terminal methylation motif 3 28 1.4E-7 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Tharo_2240 5b209b5862f848fa8e976445681a08d8 222 SUPERFAMILY SSF54523 142 201 7.14E-5 T 14-10-2018 Tharo_2240 5b209b5862f848fa8e976445681a08d8 222 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 7 27 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Tharo_0367 af2cc7cc67d883c47b350544a6ae6c06 95 PIRSF PIRSF039032 1 94 2.1E-33 T 14-10-2018 IPR009387 Toxin HigB-2 Tharo_1314 5390e9af7d4f3f51e0a14a04d28bf83c 345 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 330 1.9E-21 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Tharo_0165 c45978043bc426ee1635f54db7f7ac5d 280 Gene3D G3DSA:3.50.30.50 8 269 2.9E-49 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 Tharo_0165 c45978043bc426ee1635f54db7f7ac5d 280 Pfam PF04199 Putative cyclase 23 174 6.4E-34 T 14-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 Tharo_0165 c45978043bc426ee1635f54db7f7ac5d 280 SUPERFAMILY SSF102198 19 267 5.1E-57 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 Tharo_0956 53bc85d712b5c8892d83f09a7e80be71 70 SUPERFAMILY SSF143120 1 66 3.66E-17 T 14-10-2018 IPR036165 YefM-like superfamily Tharo_0956 53bc85d712b5c8892d83f09a7e80be71 70 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 58 4.8E-13 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Tharo_0956 53bc85d712b5c8892d83f09a7e80be71 70 Gene3D G3DSA:3.40.1620.40 1 53 3.6E-17 T 14-10-2018 Tharo_2457 7166a95bd381411212a485899ce50113 391 Gene3D G3DSA:2.40.230.10 156 391 9.2E-53 T 14-10-2018 IPR036541 Phospholipase A1 superfamily GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 Tharo_2457 7166a95bd381411212a485899ce50113 391 Pfam PF02253 Phospholipase A1 172 389 6.8E-36 T 14-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 Tharo_2457 7166a95bd381411212a485899ce50113 391 SUPERFAMILY SSF56931 154 390 6.8E-56 T 14-10-2018 IPR036541 Phospholipase A1 superfamily GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 Tharo_2457 7166a95bd381411212a485899ce50113 391 PRINTS PR01486 Bacterial phospholipase A1 protein signature 300 318 1.7E-17 T 14-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 Tharo_2457 7166a95bd381411212a485899ce50113 391 PRINTS PR01486 Bacterial phospholipase A1 protein signature 361 381 1.7E-17 T 14-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 Tharo_2457 7166a95bd381411212a485899ce50113 391 PRINTS PR01486 Bacterial phospholipase A1 protein signature 248 262 1.7E-17 T 14-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 Tharo_2457 7166a95bd381411212a485899ce50113 391 PRINTS PR01486 Bacterial phospholipase A1 protein signature 219 238 1.7E-17 T 14-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 Tharo_2457 7166a95bd381411212a485899ce50113 391 PRINTS PR01486 Bacterial phospholipase A1 protein signature 198 214 1.7E-17 T 14-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 Tharo_1414 6d6a893465193e809f34f8f754d089c2 223 SUPERFAMILY SSF56925 24 223 1.88E-31 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel Tharo_1414 6d6a893465193e809f34f8f754d089c2 223 Pfam PF03922 OmpW family 24 223 3.8E-63 T 14-10-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 Tharo_1414 6d6a893465193e809f34f8f754d089c2 223 Gene3D G3DSA:2.40.160.20 19 223 4.4E-73 T 14-10-2018 Tharo_1414 6d6a893465193e809f34f8f754d089c2 223 ProSitePatterns PS00695 Enterobacterial virulence outer membrane protein signature 2. 215 223 - T 14-10-2018 IPR000758 Virulence-related outer membrane protein GO:0009279 Tharo_0110 b53d79070719db32583daf0df5b8000d 113 Pfam PF03899 ATP synthase I chain 3 99 4.2E-17 T 14-10-2018 IPR005598 ATP synthase protein I Tharo_2309 7209cdd836fa538831809edc8464eeb1 601 TIGRFAM TIGR03648 Na_symport_lg: probable sodium:solute symporter, VC_2705 subfamily 7 591 2.2E-247 T 14-10-2018 IPR019899 Sodium/solute symporter, VC2705 subfamily Tharo_2309 7209cdd836fa538831809edc8464eeb1 601 Gene3D G3DSA:1.20.1730.10 364 551 5.3E-27 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily Tharo_2309 7209cdd836fa538831809edc8464eeb1 601 Gene3D G3DSA:1.20.1730.10 22 330 6.4E-35 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily Tharo_2309 7209cdd836fa538831809edc8464eeb1 601 Pfam PF00474 Sodium:solute symporter family 33 296 1.9E-31 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 Tharo_2309 7209cdd836fa538831809edc8464eeb1 601 Pfam PF00474 Sodium:solute symporter family 396 515 7.5E-17 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 Tharo_3337 06274d6a99ed5c6e7088e21ff1e37a2a 67 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 5 67 2.8E-20 T 14-10-2018 IPR010035 ThiS, thiamine-biosynthesis Tharo_3337 06274d6a99ed5c6e7088e21ff1e37a2a 67 Gene3D G3DSA:3.10.20.30 3 67 4.9E-19 T 14-10-2018 IPR012675 Beta-grasp domain superfamily Tharo_3337 06274d6a99ed5c6e7088e21ff1e37a2a 67 SUPERFAMILY SSF54285 3 66 5.72E-17 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp Tharo_3337 06274d6a99ed5c6e7088e21ff1e37a2a 67 Pfam PF02597 ThiS family 9 67 1.1E-11 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 Tharo_0873 30a1981da1c25d64bb060d1a172e890a 133 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 12 97 1.7E-25 T 14-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 Tharo_0873 30a1981da1c25d64bb060d1a172e890a 133 Pfam PF03334 Na+/H+ antiporter subunit 12 92 2.5E-26 T 14-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 Tharo_2154 9c3ac5cef888632eb3253a2fb3f3f19b 86 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 14 60 2.7E-10 T 14-10-2018 IPR010260 DNA-binding transcriptional activator AlpA Tharo_2154 9c3ac5cef888632eb3253a2fb3f3f19b 86 SUPERFAMILY SSF46955 16 64 4.58E-6 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily Tharo_2917 b351739fa41ac98c551c885088cc1f62 412 Pfam PF06792 Uncharacterised protein family (UPF0261) 5 400 3.8E-121 T 14-10-2018 IPR008322 Uncharacterised protein family UPF0261 Tharo_2917 b351739fa41ac98c551c885088cc1f62 412 Gene3D G3DSA:3.40.50.12030 187 404 7.3E-63 T 14-10-2018 Tharo_2917 b351739fa41ac98c551c885088cc1f62 412 PIRSF PIRSF033271 3 406 5.1E-94 T 14-10-2018 IPR008322 Uncharacterised protein family UPF0261 Tharo_2917 b351739fa41ac98c551c885088cc1f62 412 Gene3D G3DSA:3.40.50.12020 1 181 3.3E-50 T 14-10-2018 Tharo_1338 1f2edf305027434a20b7cf316d2f7398 188 SMART SM01322 1 175 5.2E-121 T 14-10-2018 IPR009822 YaeQ Tharo_1338 1f2edf305027434a20b7cf316d2f7398 188 Gene3D G3DSA:3.10.640.10 1 180 1.7E-77 T 14-10-2018 IPR038590 YaeQ superfamily Tharo_1338 1f2edf305027434a20b7cf316d2f7398 188 PIRSF PIRSF011484 1 179 2.0E-70 T 14-10-2018 IPR009822 YaeQ Tharo_1338 1f2edf305027434a20b7cf316d2f7398 188 SUPERFAMILY SSF52980 2 179 2.09E-71 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Tharo_1338 1f2edf305027434a20b7cf316d2f7398 188 Pfam PF07152 YaeQ protein 1 172 2.1E-77 T 14-10-2018 IPR009822 YaeQ Tharo_2262 81e4bcf5eace3dbf4f1aca1784090f96 496 SUPERFAMILY SSF81442 18 485 2.75E-59 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_2262 81e4bcf5eace3dbf4f1aca1784090f96 496 Gene3D G3DSA:1.20.210.10 17 492 1.5E-70 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_2262 81e4bcf5eace3dbf4f1aca1784090f96 496 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 18 459 6.0E-49 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_2617 f438558f9f57e1481d5dded90bc96310 350 Pfam PF13310 Virulence protein RhuM family 69 320 2.5E-113 T 14-10-2018 IPR011204 Virulence protein RhuM-like Tharo_2617 f438558f9f57e1481d5dded90bc96310 350 PIRSF PIRSF015268 2 348 7.3E-147 T 14-10-2018 IPR011204 Virulence protein RhuM-like Tharo_3466 7e2a61cc0640453f60ecb887a439260c 72 Pfam PF10892 Protein of unknown function (DUF2688) 10 58 5.7E-14 T 14-10-2018 IPR024392 Protein of unknown function DUF2688 Tharo_3466 7e2a61cc0640453f60ecb887a439260c 72 ProDom PD027691 KLEB PLASMID TRANSCRIPTION DNA-BINDING KCRA2 REGULATION 1 63 4.0E-16 T 14-10-2018 IPR024392 Protein of unknown function DUF2688 Tharo_2982 dea235528b55cf4ca70108a975b8b580 391 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 75 319 2.2E-47 T 14-10-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 Tharo_2982 dea235528b55cf4ca70108a975b8b580 391 SUPERFAMILY SSF53335 21 383 2.07E-93 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_2982 dea235528b55cf4ca70108a975b8b580 391 Gene3D G3DSA:3.40.50.12710 3 391 2.0E-128 T 14-10-2018 IPR038375 Protein arginine methyltransferase NDUFAF7 superfamily Reactome: R-HSA-6799198 Tharo_2009 52221e15e1a93ff9a6286a3682f2accf 400 Pfam PF02417 Chromate transporter 12 177 8.7E-33 T 14-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 Tharo_2009 52221e15e1a93ff9a6286a3682f2accf 400 Pfam PF02417 Chromate transporter 228 394 2.7E-39 T 14-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 Tharo_2009 52221e15e1a93ff9a6286a3682f2accf 400 TIGRFAM TIGR00937 2A51: chromate efflux transporter 18 394 1.4E-101 T 14-10-2018 IPR014047 Chromate transporter, long chain Tharo_2009 52221e15e1a93ff9a6286a3682f2accf 400 PIRSF PIRSF004810 2 400 1.1E-129 T 14-10-2018 IPR014047 Chromate transporter, long chain Tharo_0005 34a8fd8477be1edd98e93f5ff0ccb6b4 929 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 156 168 1.7E-13 T 14-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 Tharo_0005 34a8fd8477be1edd98e93f5ff0ccb6b4 929 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 453 467 1.7E-13 T 14-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 Tharo_0005 34a8fd8477be1edd98e93f5ff0ccb6b4 929 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 218 237 1.7E-13 T 14-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 Tharo_0005 34a8fd8477be1edd98e93f5ff0ccb6b4 929 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 430 452 1.7E-13 T 14-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 Tharo_0005 34a8fd8477be1edd98e93f5ff0ccb6b4 929 SUPERFAMILY SSF53335 128 498 1.69E-52 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_0005 34a8fd8477be1edd98e93f5ff0ccb6b4 929 Pfam PF01555 DNA methylase 156 483 3.1E-29 T 14-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 Tharo_0044 3df866d87c6b70ce4a80b753eb77cbd8 155 SUPERFAMILY SSF55961 2 149 5.71E-51 T 14-10-2018 Tharo_0044 3df866d87c6b70ce4a80b753eb77cbd8 155 Pfam PF08982 Domain of unknown function (DUF1857) 7 151 1.0E-34 T 14-10-2018 IPR015075 Acetylaranotin biosynthesis cluster protein L Tharo_0044 3df866d87c6b70ce4a80b753eb77cbd8 155 Gene3D G3DSA:3.30.530.20 1 154 1.8E-56 T 14-10-2018 IPR023393 START-like domain superfamily Tharo_1942 f35952b2bc1852ea7a5948d1e2c30842 164 Gene3D G3DSA:3.40.630.30 1 157 9.9E-47 T 14-10-2018 Tharo_1942 f35952b2bc1852ea7a5948d1e2c30842 164 SUPERFAMILY SSF55729 18 150 1.06E-16 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Tharo_1942 f35952b2bc1852ea7a5948d1e2c30842 164 Pfam PF13508 Acetyltransferase (GNAT) domain 43 143 2.1E-10 T 14-10-2018 IPR000182 GNAT domain Tharo_0170 d526253abec210dc2ee41a1d6ea4a31e 385 Gene3D G3DSA:1.20.1250.20 11 373 5.0E-22 T 14-10-2018 Tharo_0170 d526253abec210dc2ee41a1d6ea4a31e 385 Pfam PF07690 Major Facilitator Superfamily 28 300 4.3E-9 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Tharo_0170 d526253abec210dc2ee41a1d6ea4a31e 385 SUPERFAMILY SSF103473 6 371 4.58E-27 T 14-10-2018 IPR036259 MFS transporter superfamily Tharo_1774 c08da0c1ed11fc45510a394d36aa1549 181 Gene3D G3DSA:3.90.1720.10 11 161 5.1E-46 T 14-10-2018 Tharo_1774 c08da0c1ed11fc45510a394d36aa1549 181 Pfam PF00877 NlpC/P60 family 57 163 1.8E-29 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain Tharo_1774 c08da0c1ed11fc45510a394d36aa1549 181 SUPERFAMILY SSF54001 41 165 9.81E-44 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily Tharo_2692 a8bd353363c8a6db005ed7187d870ef2 266 Gene3D G3DSA:3.40.50.720 3 261 1.7E-93 T 14-10-2018 Tharo_2692 a8bd353363c8a6db005ed7187d870ef2 266 Pfam PF00899 ThiF family 25 257 1.7E-39 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 Tharo_2692 a8bd353363c8a6db005ed7187d870ef2 266 SUPERFAMILY SSF69572 7 263 1.96E-64 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 Tharo_0824 bdb11ec9346ffb82448e909891c325d3 196 Pfam PF05137 Fimbrial assembly protein (PilN) 100 173 1.5E-21 T 14-10-2018 IPR007813 Fimbrial assembly PilN Tharo_1323 2f6e2575173013bb14db576aff38b915 139 Gene3D G3DSA:3.10.129.10 2 137 7.4E-39 T 14-10-2018 Tharo_1323 2f6e2575173013bb14db576aff38b915 139 Pfam PF13279 Thioesterase-like superfamily 15 132 2.6E-14 T 14-10-2018 Tharo_1323 2f6e2575173013bb14db576aff38b915 139 SUPERFAMILY SSF54637 7 135 6.76E-36 T 14-10-2018 IPR029069 HotDog domain superfamily Tharo_0066 235e677b4eea9c4efc4c04db5fde647c 228 SUPERFAMILY SSF81342 2 185 4.32E-37 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 Tharo_0066 235e677b4eea9c4efc4c04db5fde647c 228 Gene3D G3DSA:1.20.950.20 1 167 1.5E-15 T 14-10-2018 Tharo_0066 235e677b4eea9c4efc4c04db5fde647c 228 Pfam PF01292 Prokaryotic cytochrome b561 8 178 2.6E-19 T 14-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 Tharo_2133 249a45f4f60ba6adcc00f41ef678ab93 153 SUPERFAMILY SSF47413 11 77 2.65E-7 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_2133 249a45f4f60ba6adcc00f41ef678ab93 153 Gene3D G3DSA:1.10.260.40 12 82 5.3E-11 T 14-10-2018 Tharo_2451 d187e2d4ab9356a132df8f4209ceaba8 815 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 8 784 19.462 T 14-10-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 Tharo_2451 d187e2d4ab9356a132df8f4209ceaba8 815 Pfam PF03968 OstA-like protein 124 239 8.3E-7 T 14-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal Tharo_2451 d187e2d4ab9356a132df8f4209ceaba8 815 Pfam PF04453 Organic solvent tolerance protein 346 724 1.8E-100 T 14-10-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 Tharo_1247 359c825a892f5a42fe89e2cfffd5f9d2 162 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 19 147 4.8E-25 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ Tharo_0704 a051dc35ad381cc8c9e6fd0b8327670a 77 TIGRFAM TIGR03758 conj_TIGR03758: integrating conjugative element protein, PFL_4701 family 2 77 1.8E-32 T 14-10-2018 IPR021676 Protein of unknown function DUF3262 Tharo_0704 a051dc35ad381cc8c9e6fd0b8327670a 77 Pfam PF11660 Protein of unknown function (DUF3262) 1 76 1.2E-26 T 14-10-2018 IPR021676 Protein of unknown function DUF3262 Tharo_1194 543e75f4c44fc40b499c521a8fd7739e 166 Pfam PF02674 Colicin V production protein 7 147 1.8E-31 T 14-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 Tharo_1483 82fb9a256196417c6c027779c317c39c 78 Pfam PF03937 Flavinator of succinate dehydrogenase 5 73 7.4E-20 T 14-10-2018 IPR005631 Flavinator of succinate dehydrogenase Tharo_1483 82fb9a256196417c6c027779c317c39c 78 SUPERFAMILY SSF109910 4 77 1.28E-19 T 14-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily Tharo_1483 82fb9a256196417c6c027779c317c39c 78 Gene3D G3DSA:1.10.150.250 1 78 4.2E-24 T 14-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily Tharo_3130 b3147264a1991fb25d68ebe0e2318cd4 79 Pfam PF11278 Protein of unknown function (DUF3079) 1 50 2.8E-33 T 14-10-2018 IPR021430 Protein of unknown function DUF3079 Tharo_0144 6a0818e02da63197840a7267adcce309 94 SUPERFAMILY SSF117991 10 94 2.22E-27 T 14-10-2018 IPR027471 YbeD-like domain superfamily Tharo_0144 6a0818e02da63197840a7267adcce309 94 Gene3D G3DSA:3.30.70.260 7 94 1.1E-31 T 14-10-2018 Tharo_0144 6a0818e02da63197840a7267adcce309 94 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 7 94 22.754 T 14-10-2018 IPR007454 Uncharacterised protein family UPF0250 Tharo_0144 6a0818e02da63197840a7267adcce309 94 Pfam PF04359 Protein of unknown function (DUF493) 12 94 1.1E-33 T 14-10-2018 IPR007454 Uncharacterised protein family UPF0250 Tharo_1552 403dc935dce43e96dddbaac5d7d467f1 146 Gene3D G3DSA:2.60.40.790 4 146 1.8E-34 T 14-10-2018 IPR008978 HSP20-like chaperone Tharo_1552 403dc935dce43e96dddbaac5d7d467f1 146 SUPERFAMILY SSF49764 19 145 1.92E-36 T 14-10-2018 IPR008978 HSP20-like chaperone Tharo_1552 403dc935dce43e96dddbaac5d7d467f1 146 Pfam PF00011 Hsp20/alpha crystallin family 45 145 3.6E-20 T 14-10-2018 IPR002068 Alpha crystallin/Hsp20 domain Tharo_2360 bf4ba31823ad4fd01f365b1121d9c978 66 Gene3D G3DSA:2.60.260.40 5 57 2.7E-10 T 14-10-2018 Tharo_2360 bf4ba31823ad4fd01f365b1121d9c978 66 Pfam PF10276 Zinc-finger domain 29 55 4.9E-8 T 14-10-2018 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_2864 ae7a0a6f8cd3073577553d28ac45ea80 358 Pfam PF03595 Voltage-dependent anion channel 16 337 1.8E-50 T 14-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 Tharo_2864 ae7a0a6f8cd3073577553d28ac45ea80 358 Gene3D G3DSA:1.50.10.150 11 346 3.9E-10 T 14-10-2018 IPR038665 Voltage-dependent anion channel superfamily Tharo_1306 eec1d39e068b8c58c488ae5373d99666 432 TIGRFAM TIGR02260 benz_CoA_red_B: benzoyl-CoA reductase, subunit B 8 420 3.1E-286 T 14-10-2018 IPR011955 Benzoyl-CoA reductase, subunit B KEGG: 00362+1.3.7.8 Tharo_1306 eec1d39e068b8c58c488ae5373d99666 432 Gene3D G3DSA:3.40.50.11900 276 428 5.3E-7 T 14-10-2018 Tharo_1306 eec1d39e068b8c58c488ae5373d99666 432 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 50 419 1.1E-47 T 14-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit Tharo_0669 0369253c0c47d3ad7c8d17b3ff6f7126 401 Pfam PF03616 Sodium/glutamate symporter 2 371 2.9E-93 T 14-10-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 Tharo_0669 0369253c0c47d3ad7c8d17b3ff6f7126 401 Hamap MF_02062 Sodium/glutamate symporter [gltS]. 1 401 21.081 T 14-10-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 Tharo_0669 0369253c0c47d3ad7c8d17b3ff6f7126 401 TIGRFAM TIGR00210 gltS: sodium/glutamate symporter 2 398 5.7E-108 T 14-10-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 Tharo_1686 fb7190609794c017398078c7874f0738 511 Pfam PF03023 MviN-like protein 28 470 1.4E-145 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Tharo_1686 fb7190609794c017398078c7874f0738 511 PIRSF PIRSF002869 1 510 1.4E-169 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Tharo_1686 fb7190609794c017398078c7874f0738 511 PRINTS PR01806 Virulence factor MviN signature 157 178 1.4E-83 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Tharo_1686 fb7190609794c017398078c7874f0738 511 PRINTS PR01806 Virulence factor MviN signature 259 285 1.4E-83 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Tharo_1686 fb7190609794c017398078c7874f0738 511 PRINTS PR01806 Virulence factor MviN signature 52 68 1.4E-83 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Tharo_1686 fb7190609794c017398078c7874f0738 511 PRINTS PR01806 Virulence factor MviN signature 357 376 1.4E-83 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Tharo_1686 fb7190609794c017398078c7874f0738 511 PRINTS PR01806 Virulence factor MviN signature 133 157 1.4E-83 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Tharo_1686 fb7190609794c017398078c7874f0738 511 PRINTS PR01806 Virulence factor MviN signature 409 426 1.4E-83 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Tharo_1686 fb7190609794c017398078c7874f0738 511 PRINTS PR01806 Virulence factor MviN signature 33 52 1.4E-83 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Tharo_1686 fb7190609794c017398078c7874f0738 511 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 3 502 2.4E-156 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Tharo_1686 fb7190609794c017398078c7874f0738 511 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 3 466 20.852 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Tharo_2193 743b4c1f2fcc3b2e51d291d4490c0d19 330 SUPERFAMILY SSF52540 42 162 2.77E-11 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2193 743b4c1f2fcc3b2e51d291d4490c0d19 330 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 2 324 38.308 T 14-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 Tharo_2193 743b4c1f2fcc3b2e51d291d4490c0d19 330 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 18 322 9.2E-99 T 14-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 Tharo_2193 743b4c1f2fcc3b2e51d291d4490c0d19 330 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 20 315 9.7E-66 T 14-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 Tharo_1084 5e02da619d9d3d9db772b1b76abd70ad 199 SUPERFAMILY SSF56024 47 192 6.5E-30 T 14-10-2018 Tharo_1084 5e02da619d9d3d9db772b1b76abd70ad 199 Pfam PF13091 PLD-like domain 59 182 3.6E-21 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 Tharo_1084 5e02da619d9d3d9db772b1b76abd70ad 199 Gene3D G3DSA:3.30.870.10 40 192 7.7E-36 T 14-10-2018 Tharo_0493 d405170143386fcc96eed98708ebb361 308 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 223 288 3.5E-12 T 14-10-2018 IPR037682 TonB, C-terminal GO:0055085 Tharo_0493 d405170143386fcc96eed98708ebb361 308 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 224 300 3.9E-13 T 14-10-2018 IPR006260 TonB/TolA, C-terminal Tharo_0493 d405170143386fcc96eed98708ebb361 308 SUPERFAMILY SSF74653 150 302 5.62E-21 T 14-10-2018 Tharo_1844 9486e12abdafffa51d56c387feeb38d7 270 Gene3D G3DSA:1.10.8.350 48 210 2.0E-66 T 14-10-2018 Tharo_1844 9486e12abdafffa51d56c387feeb38d7 270 Pfam PF13406 Transglycosylase SLT domain 35 268 1.8E-83 T 14-10-2018 IPR031304 Transglycosylase SLT domain 2 Tharo_1844 9486e12abdafffa51d56c387feeb38d7 270 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 35 268 1.8E-86 T 14-10-2018 IPR011970 Lytic murein transglycosylase Tharo_1844 9486e12abdafffa51d56c387feeb38d7 270 Gene3D G3DSA:1.10.530.10 77 264 2.0E-66 T 14-10-2018 Tharo_1844 9486e12abdafffa51d56c387feeb38d7 270 SUPERFAMILY SSF53955 21 268 3.0E-75 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily Tharo_0891 ccd71ff69bf3102a78a6c7b318966110 639 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 138 604 9.7E-216 T 14-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 Tharo_0891 ccd71ff69bf3102a78a6c7b318966110 639 Pfam PF13667 ThiC-associated domain 21 98 2.8E-34 T 14-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 Tharo_0891 ccd71ff69bf3102a78a6c7b318966110 639 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 138 605 99.334 T 14-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 Tharo_0891 ccd71ff69bf3102a78a6c7b318966110 639 Pfam PF01964 Radical SAM ThiC family 139 600 1.1E-197 T 14-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 Tharo_0891 ccd71ff69bf3102a78a6c7b318966110 639 Gene3D G3DSA:3.20.20.540 223 536 8.5E-152 T 14-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 Tharo_1179 f1f32b8029b891bb0a09d1bbb0fc0486 272 Pfam PF01435 Peptidase family M48 92 257 1.8E-32 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 Tharo_1669 66a556113140688e897c7cd65bc05c60 137 SUPERFAMILY SSF52833 27 111 6.85E-17 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_1669 66a556113140688e897c7cd65bc05c60 137 Gene3D G3DSA:3.40.30.10 14 113 4.0E-13 T 14-10-2018 Tharo_1669 66a556113140688e897c7cd65bc05c60 137 Pfam PF00085 Thioredoxin 27 94 1.1E-11 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 Tharo_1369 de16b836af7e83e73f0f9f3ed7e80070 188 TIGRFAM TIGR03406 FeS_long_SufT: probable FeS assembly SUF system protein SufT 12 187 1.1E-66 T 14-10-2018 IPR017776 FeS assembly SUF system protein SufT, putative Tharo_1369 de16b836af7e83e73f0f9f3ed7e80070 188 Gene3D G3DSA:3.30.300.130 80 188 7.2E-34 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Tharo_1369 de16b836af7e83e73f0f9f3ed7e80070 188 SUPERFAMILY SSF117916 87 186 4.9E-27 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Tharo_1369 de16b836af7e83e73f0f9f3ed7e80070 188 Pfam PF01883 Iron-sulfur cluster assembly protein 90 164 1.4E-14 T 14-10-2018 IPR002744 MIP18 family-like Tharo_3292 88043b1a18cfafd7453c27ed1ed4ebf8 165 Gene3D G3DSA:2.30.110.10 1 164 1.2E-46 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 Tharo_3292 88043b1a18cfafd7453c27ed1ed4ebf8 165 SUPERFAMILY SSF50475 12 163 1.42E-45 T 14-10-2018 Tharo_3292 88043b1a18cfafd7453c27ed1ed4ebf8 165 SMART SM00903 19 162 2.4E-59 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 Tharo_3292 88043b1a18cfafd7453c27ed1ed4ebf8 165 Pfam PF01613 Flavin reductase like domain 21 163 1.5E-32 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 Tharo_0630 634fea2ffae4b205d9d6c6961363068c 257 Pfam PF01061 ABC-2 type transporter 10 220 7.2E-34 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 Tharo_0630 634fea2ffae4b205d9d6c6961363068c 257 PRINTS PR00164 ABC-2 type transport system membrane protein signature 177 196 1.2E-8 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 Tharo_0630 634fea2ffae4b205d9d6c6961363068c 257 PRINTS PR00164 ABC-2 type transport system membrane protein signature 197 216 1.2E-8 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 Tharo_0630 634fea2ffae4b205d9d6c6961363068c 257 PRINTS PR00164 ABC-2 type transport system membrane protein signature 59 81 1.2E-8 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 Tharo_0630 634fea2ffae4b205d9d6c6961363068c 257 PIRSF PIRSF006648 4 255 8.0E-21 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 Tharo_2810 e446bf1a2c533f568d118320312f737f 125 Pfam PF01475 Ferric uptake regulator family 2 105 2.8E-10 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 Tharo_2810 e446bf1a2c533f568d118320312f737f 125 SUPERFAMILY SSF46785 2 113 2.38E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_2810 e446bf1a2c533f568d118320312f737f 125 Gene3D G3DSA:3.30.1490.190 68 119 1.1E-6 T 14-10-2018 Tharo_2810 e446bf1a2c533f568d118320312f737f 125 Gene3D G3DSA:1.10.10.10 2 56 2.0E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1613 093bf43213069ab6e98cc35d4f69f974 91 Pfam PF05768 Glutaredoxin-like domain (DUF836) 11 80 1.4E-10 T 14-10-2018 IPR008554 Glutaredoxin-like Tharo_1613 093bf43213069ab6e98cc35d4f69f974 91 SUPERFAMILY SSF52833 5 81 2.06E-13 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_1613 093bf43213069ab6e98cc35d4f69f974 91 Gene3D G3DSA:3.40.30.10 6 82 1.4E-17 T 14-10-2018 Tharo_1561 2b134f653e82322b4587e7c77c3f9cdb 396 TIGRFAM TIGR00540 TPR_hemY_coli: heme biosynthesis-associated TPR protein 2 387 9.1E-105 T 14-10-2018 IPR005254 Heme biosynthesis-associated TPR protein GO:0016020|GO:0042168 Tharo_1561 2b134f653e82322b4587e7c77c3f9cdb 396 Gene3D G3DSA:1.25.40.10 152 392 1.0E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_1561 2b134f653e82322b4587e7c77c3f9cdb 396 SUPERFAMILY SSF48452 91 384 9.7E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Tharo_1561 2b134f653e82322b4587e7c77c3f9cdb 396 Pfam PF07219 HemY protein N-terminus 26 130 1.3E-29 T 14-10-2018 IPR010817 HemY, N-terminal Tharo_1906 d81a3f9a51264ef2475840b0e14e5ce9 360 PIRSF PIRSF005508 5 358 1.9E-115 T 14-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 Tharo_1906 d81a3f9a51264ef2475840b0e14e5ce9 360 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 18 344 2.4E-115 T 14-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 Tharo_1906 d81a3f9a51264ef2475840b0e14e5ce9 360 Gene3D G3DSA:1.20.1530.20 19 350 7.1E-19 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily Tharo_1906 d81a3f9a51264ef2475840b0e14e5ce9 360 Pfam PF01758 Sodium Bile acid symporter family 63 257 1.4E-37 T 14-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 Tharo_3232 8c68ceb1cde0dff635cb0a89d0b98658 167 TIGRFAM TIGR02683 upstrm_HI1419: putative addiction module killer protein 1 79 7.5E-33 T 14-10-2018 IPR014056 Addiction module killer protein, predicted Tharo_3232 8c68ceb1cde0dff635cb0a89d0b98658 167 TIGRFAM TIGR02684 dnstrm_HI1420: probable addiction module antidote protein 68 131 1.3E-18 T 14-10-2018 IPR014057 Uncharacterized protein HI1420 Tharo_0736 9617d806ca20d7f91584670a7f70b8e8 266 Pfam PF08900 Domain of unknown function (DUF1845) 12 222 3.8E-79 T 14-10-2018 IPR014996 Integrating conjugative element protein, PFL4669 Tharo_0736 9617d806ca20d7f91584670a7f70b8e8 266 TIGRFAM TIGR03761 ICE_PFL4669: integrating conjugative element protein, PFL_4669 family 13 225 1.1E-88 T 14-10-2018 IPR014996 Integrating conjugative element protein, PFL4669 Tharo_0382 8ce183837fbc3ca60a052c26c6b443bc 141 Gene3D G3DSA:3.30.160.250 1 86 5.4E-23 T 14-10-2018 Tharo_0382 8ce183837fbc3ca60a052c26c6b443bc 141 SUPERFAMILY SSF143100 2 66 1.44E-15 T 14-10-2018 IPR035069 TTHA1013/TTHA0281-like Tharo_0382 8ce183837fbc3ca60a052c26c6b443bc 141 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 3 127 1.8E-51 T 14-10-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system Tharo_0280 6e3e07e186addc4ae41e7712b097f9c2 505 Pfam PF07916 TraG-like protein, N-terminal region 10 487 1.8E-98 T 14-10-2018 IPR012931 TraG-like, N-terminal Tharo_3248 9835b6876533f3b20e0f33597430a629 276 PIRSF PIRSF037318 7 271 1.8E-136 T 14-10-2018 IPR017172 Lipopolysaccharide core heptose(I) kinase rfaP GO:0009103|GO:0016301 Tharo_3248 9835b6876533f3b20e0f33597430a629 276 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 26 236 1.6E-61 T 14-10-2018 Tharo_3248 9835b6876533f3b20e0f33597430a629 276 SUPERFAMILY SSF56112 38 220 5.72E-9 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Tharo_1862 05b13afef02ee56d8c49cf94d7960d9c 185 SMART SM00248 79 108 2.5E-6 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 Tharo_1862 05b13afef02ee56d8c49cf94d7960d9c 185 SMART SM00248 112 141 0.033 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 Tharo_1862 05b13afef02ee56d8c49cf94d7960d9c 185 SMART SM00248 46 75 9.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 Tharo_1862 05b13afef02ee56d8c49cf94d7960d9c 185 Gene3D G3DSA:1.25.40.20 2 183 3.2E-42 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily Tharo_1862 05b13afef02ee56d8c49cf94d7960d9c 185 Pfam PF12796 Ankyrin repeats (3 copies) 20 110 4.1E-11 T 14-10-2018 IPR020683 Ankyrin repeat-containing domain Tharo_1862 05b13afef02ee56d8c49cf94d7960d9c 185 SUPERFAMILY SSF48403 18 166 1.03E-34 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily Tharo_2446 55e349455083680898d6d40f6e08745f 63 Pfam PF11127 Protein of unknown function (DUF2892) 1 60 3.0E-22 T 14-10-2018 IPR021309 Protein of unknown function DUF2892 Tharo_2834 25ff6910a2cb84f7e878e4891a20c9df 68 Gene3D G3DSA:2.10.70.10 29 68 2.6E-14 T 14-10-2018 Tharo_2834 25ff6910a2cb84f7e878e4891a20c9df 68 Pfam PF10636 Hemin uptake protein hemP 33 68 1.3E-17 T 14-10-2018 IPR019600 Hemin uptake protein HemP Tharo_0239 3988097a87c95f83725478d9add2b4e0 183 Gene3D G3DSA:3.10.180.10 3 171 7.1E-33 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Tharo_0239 3988097a87c95f83725478d9add2b4e0 183 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 136 3.9E-16 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Tharo_0239 3988097a87c95f83725478d9add2b4e0 183 SUPERFAMILY SSF54593 4 159 1.17E-33 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Tharo_0135 ab54b886557c28debb1c42ce41ffb294 95 SUPERFAMILY SSF141000 3 93 2.22E-27 T 14-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 Tharo_0135 ab54b886557c28debb1c42ce41ffb294 95 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 22.322 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 Tharo_0135 ab54b886557c28debb1c42ce41ffb294 95 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 3 95 6.9E-30 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 Tharo_0135 ab54b886557c28debb1c42ce41ffb294 95 Gene3D G3DSA:1.10.20.60 1 93 1.6E-24 T 14-10-2018 Tharo_0135 ab54b886557c28debb1c42ce41ffb294 95 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 90 2.8E-17 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 Tharo_0896 c8b2f830d8165c29ecadfb2c35321bef 453 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 55 232 1.3E-61 T 14-10-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 Tharo_0896 c8b2f830d8165c29ecadfb2c35321bef 453 Pfam PF00534 Glycosyl transferases group 1 266 417 7.2E-8 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 Tharo_0896 c8b2f830d8165c29ecadfb2c35321bef 453 Gene3D G3DSA:3.40.50.11720 55 230 2.7E-47 T 14-10-2018 IPR038107 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal domain superfamily KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 Tharo_0896 c8b2f830d8165c29ecadfb2c35321bef 453 SUPERFAMILY SSF53756 74 435 2.69E-15 T 14-10-2018 Tharo_0896 c8b2f830d8165c29ecadfb2c35321bef 453 Gene3D G3DSA:3.40.50.2000 240 420 4.3E-60 T 14-10-2018 Tharo_0007 785a019a27226685f662b00535682f20 703 SUPERFAMILY SSF143011 1 81 6.93E-7 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_0007 785a019a27226685f662b00535682f20 703 Pfam PF00580 UvrD/REP helicase N-terminal domain 239 310 4.2E-9 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 Tharo_0007 785a019a27226685f662b00535682f20 703 Gene3D G3DSA:3.40.50.300 508 701 7.0E-32 T 14-10-2018 Tharo_0007 785a019a27226685f662b00535682f20 703 Pfam PF13361 UvrD-like helicase C-terminal domain 619 687 3.4E-13 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Tharo_0007 785a019a27226685f662b00535682f20 703 SUPERFAMILY SSF52540 229 691 1.65E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0301 070a49b8a157cead7b091195ef43d7b6 246 Gene3D G3DSA:3.40.30.10 53 222 6.0E-35 T 14-10-2018 Tharo_0301 070a49b8a157cead7b091195ef43d7b6 246 Pfam PF13462 Thioredoxin 53 196 6.0E-18 T 14-10-2018 IPR012336 Thioredoxin-like fold Tharo_0301 070a49b8a157cead7b091195ef43d7b6 246 SUPERFAMILY SSF52833 39 218 4.41E-32 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_1765 c7a90a6085a902ab3d8d7b3b84530f5c 275 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 55 255 1.5E-28 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 Tharo_1765 c7a90a6085a902ab3d8d7b3b84530f5c 275 Gene3D G3DSA:3.40.630.40 53 260 6.6E-28 T 14-10-2018 Tharo_1765 c7a90a6085a902ab3d8d7b3b84530f5c 275 SUPERFAMILY SSF53187 55 258 1.03E-26 T 14-10-2018 Tharo_1765 c7a90a6085a902ab3d8d7b3b84530f5c 275 SMART SM00646 114 255 1.1E-4 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 Tharo_2785 0cf372786aea6cc51e5cbb57273af89a 157 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 20 95 1.1E-5 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 Tharo_2785 0cf372786aea6cc51e5cbb57273af89a 157 SUPERFAMILY SSF50475 13 95 1.59E-14 T 14-10-2018 Tharo_2785 0cf372786aea6cc51e5cbb57273af89a 157 Gene3D G3DSA:2.30.110.10 11 144 4.8E-8 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 Tharo_1495 2bd1576e6d7d0f7f5ee403b6cbf3bd9d 115 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 14 81 1.9E-24 T 14-10-2018 IPR018720 Domain of unknown function DUF2249 Tharo_0035 3773a5a2bda9774383b2dd9a85ea0ad0 72 Pfam PF05433 Glycine zipper 2TM domain 31 69 3.4E-7 T 14-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 Tharo_2241 715c94f69a46cffb61a784ac467799e3 141 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 32 1.1E-4 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Tharo_2241 715c94f69a46cffb61a784ac467799e3 141 Pfam PF07963 Prokaryotic N-terminal methylation motif 9 33 6.3E-8 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Tharo_1037 e0cc8fabd752fe1594e3b4f05a70ee88 584 Gene3D G3DSA:2.40.160.50 280 582 3.0E-66 T 14-10-2018 Tharo_1037 e0cc8fabd752fe1594e3b4f05a70ee88 584 Pfam PF01103 Surface antigen 391 583 6.4E-27 T 14-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 Tharo_1037 e0cc8fabd752fe1594e3b4f05a70ee88 584 Gene3D G3DSA:3.10.20.310 203 278 1.1E-10 T 14-10-2018 Tharo_1378 d7d31daa92e7b20935332b784d05d3ab 195 SUPERFAMILY SSF48613 4 188 1.89E-32 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 Tharo_1378 d7d31daa92e7b20935332b784d05d3ab 195 Gene3D G3DSA:1.20.910.10 1 193 1.3E-42 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 Tharo_1378 d7d31daa92e7b20935332b784d05d3ab 195 Pfam PF01126 Heme oxygenase 5 188 3.3E-6 T 14-10-2018 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 Tharo_2280 4a996fc359ce2d3081a5e5164b548963 175 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 Tharo_2280 4a996fc359ce2d3081a5e5164b548963 175 Pfam PF00719 Inorganic pyrophosphatase 18 169 1.0E-50 T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 Tharo_2280 4a996fc359ce2d3081a5e5164b548963 175 SUPERFAMILY SSF50324 6 174 1.7E-64 T 14-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 Tharo_2280 4a996fc359ce2d3081a5e5164b548963 175 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 35.597 T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 Tharo_2280 4a996fc359ce2d3081a5e5164b548963 175 Gene3D G3DSA:3.90.80.10 1 175 2.4E-66 T 14-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 Tharo_1814 c2277f3998357b33a911d1a6cb80941c 306 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 294 1.6E-36 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Tharo_3463 29458301e3e40f26708b90616b7fad2b 37 Pfam PF10959 Protein of unknown function (DUF2761) 1 32 8.4E-14 T 14-10-2018 IPR024249 Protein of unknown function DUF2761 Tharo_3463 29458301e3e40f26708b90616b7fad2b 37 ProDom PD029589 PLASMID KLEF KCRB4 STABLE INHERITANCE INITIATION ALTERNATIVE 1 29 5.0E-9 T 14-10-2018 IPR024249 Protein of unknown function DUF2761 Tharo_2953 f504493edb25257e51ab0e9811223f73 873 Pfam PF11874 Domain of unknown function (DUF3394) 682 862 1.7E-65 T 14-10-2018 IPR021814 Protein of unknown function DUF3394 Tharo_2953 f504493edb25257e51ab0e9811223f73 873 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 142 408 3.5E-50 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit Tharo_2953 f504493edb25257e51ab0e9811223f73 873 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 39 732 1.9E-207 T 14-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ Tharo_2780 458d19cd33889d55b7ac7d7f61347808 84 Pfam PF09662 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) 2 84 2.7E-49 T 14-10-2018 IPR014097 Phenylphosphate carboxylase, gamma subunit Tharo_2780 458d19cd33889d55b7ac7d7f61347808 84 TIGRFAM TIGR02725 phenyl_P_gamma: phenylphosphate carboxylase, gamma subunit 1 84 1.8E-58 T 14-10-2018 IPR014097 Phenylphosphate carboxylase, gamma subunit Tharo_1295 0b8629b4e522aede60bf2d4f21490ec6 293 Pfam PF04976 DMSO reductase anchor subunit (DmsC) 23 189 6.7E-5 T 14-10-2018 IPR007059 DMSO reductase anchor subunit (DmsC) GO:0016021|GO:0019645 Tharo_2711 c0532cecbd619f60a382fe9dd083b75c 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 1.2E-26 T 14-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Tharo_2711 c0532cecbd619f60a382fe9dd083b75c 101 Gene3D G3DSA:4.10.830.10 41 101 2.1E-23 T 14-10-2018 Tharo_2711 c0532cecbd619f60a382fe9dd083b75c 101 SUPERFAMILY SSF57716 2 101 7.84E-37 T 14-10-2018 Tharo_2711 c0532cecbd619f60a382fe9dd083b75c 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.881 T 14-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid Tharo_2711 c0532cecbd619f60a382fe9dd083b75c 101 ProSitePatterns PS00527 Ribosomal protein S14 signature. 63 85 - T 14-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Tharo_0288 0612213b41dbe0f0fbc01b84372bd464 239 SUPERFAMILY SSF52317 22 199 3.82E-40 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Tharo_0288 0612213b41dbe0f0fbc01b84372bd464 239 Gene3D G3DSA:3.40.50.880 1 229 1.6E-54 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like Tharo_0288 0612213b41dbe0f0fbc01b84372bd464 239 Pfam PF00117 Glutamine amidotransferase class-I 29 182 8.0E-14 T 14-10-2018 IPR017926 Glutamine amidotransferase Tharo_3171 baece55b298fd73114f925a710ce887e 97 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 23 81 2.9E-7 T 14-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 Tharo_2937 cf5ee49a130147cae058967758c00262 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 66 1.1E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_2937 cf5ee49a130147cae058967758c00262 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 74 97 1.1E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_2937 cf5ee49a130147cae058967758c00262 236 SUPERFAMILY SSF48498 120 232 2.43E-16 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Tharo_2937 cf5ee49a130147cae058967758c00262 236 Gene3D G3DSA:1.10.357.10 95 232 7.6E-27 T 14-10-2018 Tharo_2937 cf5ee49a130147cae058967758c00262 236 SUPERFAMILY SSF46689 40 123 8.98E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Tharo_2937 cf5ee49a130147cae058967758c00262 236 Pfam PF00440 Bacterial regulatory proteins, tetR family 53 97 7.5E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Tharo_2937 cf5ee49a130147cae058967758c00262 236 Gene3D G3DSA:1.10.10.60 31 94 1.6E-18 T 14-10-2018 Tharo_2491 c90838e190edb2a14033848eb132e1c4 230 SUPERFAMILY SSF52540 17 209 3.78E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_2491 c90838e190edb2a14033848eb132e1c4 230 Pfam PF00308 Bacterial dnaA protein 92 206 3.4E-9 T 14-10-2018 IPR013317 Chromosomal replication initiator protein DnaA Tharo_2491 c90838e190edb2a14033848eb132e1c4 230 Gene3D G3DSA:1.10.8.60 159 225 3.8E-21 T 14-10-2018 Tharo_2491 c90838e190edb2a14033848eb132e1c4 230 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 3 225 3.8E-66 T 14-10-2018 IPR017788 DnaA regulatory inactivator Hda GO:0032297 Tharo_2491 c90838e190edb2a14033848eb132e1c4 230 Gene3D G3DSA:3.40.50.300 38 157 4.4E-20 T 14-10-2018 Tharo_2307 22fedcfe1242a59838ab6891fc93d9ad 117 TIGRFAM TIGR03647 Na_symport_sm: putative solute:sodium symporter small subunit 40 115 4.2E-30 T 14-10-2018 IPR019886 Sodium symporter small subunit, predicted Tharo_2307 22fedcfe1242a59838ab6891fc93d9ad 117 Pfam PF13937 Domain of unknown function (DUF4212) 38 114 1.4E-28 T 14-10-2018 IPR019886 Sodium symporter small subunit, predicted Tharo_1103 a35df9064f4bf5ad7634ef5b3e2d113d 284 Gene3D G3DSA:3.40.830.10 1 284 1.0E-92 T 14-10-2018 Tharo_1103 a35df9064f4bf5ad7634ef5b3e2d113d 284 SUPERFAMILY SSF53213 2 283 4.84E-92 T 14-10-2018 Tharo_1103 a35df9064f4bf5ad7634ef5b3e2d113d 284 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 8 277 2.7E-87 T 14-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 Tharo_1332 f2a7164654d4f2263cd81a5879f26364 184 SUPERFAMILY SSF51161 3 167 5.68E-48 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily Tharo_1332 f2a7164654d4f2263cd81a5879f26364 184 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 14 45 2.0E-4 T 14-10-2018 IPR001451 Hexapeptide repeat Tharo_1332 f2a7164654d4f2263cd81a5879f26364 184 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 121 8.7E-10 T 14-10-2018 IPR001451 Hexapeptide repeat Tharo_1332 f2a7164654d4f2263cd81a5879f26364 184 Gene3D G3DSA:2.160.10.10 1 173 1.7E-63 T 14-10-2018 Tharo_1616 d883b542dbde0bb56a1cc3518e68536f 120 Pfam PF16137 Domain of unknown function (DUF4845) 30 112 2.0E-20 T 14-10-2018 IPR032314 Protein of unknown function DUF4845 Tharo_0758 8b3265b77910910dfb4b22160cf2f5c0 228 SUPERFAMILY SSF52833 64 195 6.58E-5 T 14-10-2018 IPR036249 Thioredoxin-like superfamily Tharo_2789 3dffe4f9aa8ecb3b3c5826ba00b2d204 117 Pfam PF04228 Putative neutral zinc metallopeptidase 1 112 2.4E-50 T 14-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative Tharo_2380 ca04653ce761e66bbdb1d4f28cd0c8cb 197 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 162 9.4E-24 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ Tharo_2200 edb27c9980eb2a8558031df68dc88505 182 Pfam PF14803 Nudix N-terminal 2 35 3.3E-17 T 14-10-2018 IPR029401 Nudix hydrolase, N-terminal KEGG: 00230+3.6.1.13|KEGG: 00740+3.6.1.18 Tharo_2200 edb27c9980eb2a8558031df68dc88505 182 Gene3D G3DSA:2.20.70.10 1 35 2.2E-18 T 14-10-2018 Tharo_2200 edb27c9980eb2a8558031df68dc88505 182 SUPERFAMILY SSF55811 2 164 1.9E-37 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Tharo_2200 edb27c9980eb2a8558031df68dc88505 182 Pfam PF00293 NUDIX domain 41 141 8.6E-11 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Tharo_2200 edb27c9980eb2a8558031df68dc88505 182 Gene3D G3DSA:3.90.79.10 36 176 8.7E-37 T 14-10-2018 Tharo_2345 8e0cd88d9bfafa3f881af659b2557f1e 201 Pfam PF04519 Polymer-forming cytoskeletal 77 172 3.7E-17 T 14-10-2018 IPR007607 Bactofilin A/B Tharo_1945 aa9ac4a929aa2e44bcf9a3189e9cd352 77 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 56 6.4E-9 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Tharo_1945 aa9ac4a929aa2e44bcf9a3189e9cd352 77 SUPERFAMILY SSF89447 4 63 1.2E-5 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily Tharo_1945 aa9ac4a929aa2e44bcf9a3189e9cd352 77 Gene3D G3DSA:2.10.260.10 1 77 2.8E-31 T 14-10-2018 Tharo_1854 35ebc6d67374590e1b88925c7a9dbde5 112 Pfam PF13663 Domain of unknown function (DUF4148) 7 71 2.3E-11 T 14-10-2018 IPR025421 Protein of unknown function DUF4148 Tharo_2861 87e61a6a34f40489b89d6ed706cb0375 552 SUPERFAMILY SSF141322 457 521 1.02E-9 T 14-10-2018 Tharo_2861 87e61a6a34f40489b89d6ed706cb0375 552 Gene3D G3DSA:2.40.50.140 460 525 4.8E-11 T 14-10-2018 Tharo_2861 87e61a6a34f40489b89d6ed706cb0375 552 SUPERFAMILY SSF52096 45 283 4.55E-23 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Tharo_2861 87e61a6a34f40489b89d6ed706cb0375 552 Pfam PF01957 NfeD-like C-terminal, partner-binding 384 522 1.8E-30 T 14-10-2018 IPR002810 NfeD-like, C-terminal domain Tharo_0975 90d3536f4115952af34960826281eaaa 79 Pfam PF13744 Helix-turn-helix domain 13 65 1.1E-8 T 14-10-2018 IPR039554 HigA2-like, helix-turn-helix domain Tharo_0975 90d3536f4115952af34960826281eaaa 79 Gene3D G3DSA:1.10.260.40 1 79 1.3E-12 T 14-10-2018 Tharo_0975 90d3536f4115952af34960826281eaaa 79 SMART SM00530 13 68 1.1E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Tharo_0975 90d3536f4115952af34960826281eaaa 79 SUPERFAMILY SSF47413 9 70 9.21E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Tharo_3361 3b4e36de73b407687e3cad560f6ea960 114 Gene3D G3DSA:3.10.450.40 37 104 4.3E-7 T 14-10-2018 Tharo_3361 3b4e36de73b407687e3cad560f6ea960 114 Pfam PF03413 Peptidase propeptide and YPEB domain 49 97 6.0E-7 T 14-10-2018 IPR025711 PepSY domain Tharo_0974 7a1878bd85b6638d06ae3e4d1e0c126d 442 Pfam PF13657 HipA N-terminal domain 10 111 2.0E-22 T 14-10-2018 IPR017508 HipA, N-terminal subdomain 1 Tharo_0974 7a1878bd85b6638d06ae3e4d1e0c126d 442 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 10 111 8.6E-28 T 14-10-2018 IPR017508 HipA, N-terminal subdomain 1 Tharo_0974 7a1878bd85b6638d06ae3e4d1e0c126d 442 Pfam PF07804 HipA-like C-terminal domain 160 408 2.0E-54 T 14-10-2018 IPR012893 HipA-like, C-terminal Tharo_3277 6a7938297e65ec8ff688a1c72a1f28ad 167 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 25 153 2.7E-37 T 14-10-2018 IPR011605 NusB antitermination factor GO:0006353 Tharo_3277 6a7938297e65ec8ff688a1c72a1f28ad 167 Gene3D G3DSA:1.10.940.10 19 159 1.2E-40 T 14-10-2018 IPR035926 NusB-like superfamily Tharo_3277 6a7938297e65ec8ff688a1c72a1f28ad 167 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 23 155 20.454 T 14-10-2018 IPR011605 NusB antitermination factor GO:0006353 Tharo_3277 6a7938297e65ec8ff688a1c72a1f28ad 167 SUPERFAMILY SSF48013 23 156 1.07E-37 T 14-10-2018 IPR035926 NusB-like superfamily Tharo_3277 6a7938297e65ec8ff688a1c72a1f28ad 167 Pfam PF01029 NusB family 26 151 7.8E-31 T 14-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 Tharo_0019 e56c5c5223434989097567483dd9601c 186 Gene3D G3DSA:3.30.2010.10 81 176 5.7E-7 T 14-10-2018 Tharo_0019 e56c5c5223434989097567483dd9601c 186 Pfam PF01863 Protein of unknown function DUF45 112 171 2.9E-11 T 14-10-2018 IPR002725 Protein of unknown function DUF45 Tharo_1803 2b9947b6803fb7c7d434fd5a5c79b62d 351 Pfam PF04332 Protein of unknown function (DUF475) 61 346 8.7E-113 T 14-10-2018 IPR007427 Protein of unknown function DUF475 Tharo_1072 462ac54fd627885a1c1b460cce9746d0 414 Pfam PF03060 Nitronate monooxygenase 164 306 2.2E-23 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 Tharo_1072 462ac54fd627885a1c1b460cce9746d0 414 SUPERFAMILY SSF51412 17 319 3.21E-34 T 14-10-2018 Tharo_2516 86b7121fe00bd571a0f3f33e065d5866 360 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 2 346 7.3E-112 T 14-10-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 Tharo_2516 86b7121fe00bd571a0f3f33e065d5866 360 Pfam PF03739 Predicted permease YjgP/YjgQ family 7 346 1.0E-53 T 14-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 Tharo_3314 5dd7f18025b51ee9b494d0a61965e106 403 SUPERFAMILY SSF50939 54 369 1.47E-16 T 14-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 Tharo_3314 5dd7f18025b51ee9b494d0a61965e106 403 Gene3D G3DSA:2.120.10.10 51 256 1.1E-6 T 14-10-2018 Tharo_0602 fc8a75815c4311e2552515a6705d7b73 342 Pfam PF02562 PhoH-like protein 108 311 3.9E-91 T 14-10-2018 IPR003714 PhoH-like protein GO:0005524 Tharo_0602 fc8a75815c4311e2552515a6705d7b73 342 Gene3D G3DSA:3.40.50.300 105 311 8.6E-70 T 14-10-2018 Tharo_0602 fc8a75815c4311e2552515a6705d7b73 342 SUPERFAMILY SSF52540 107 283 7.89E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0610 d8e415f119cc60aeb65bfacd7e3cf83c 188 TIGRFAM TIGR01841 phasin: phasin family protein 28 111 4.1E-21 T 14-10-2018 IPR010127 Phasin, subfamily 1 Tharo_0610 d8e415f119cc60aeb65bfacd7e3cf83c 188 Pfam PF09361 Phasin protein 8 107 6.0E-31 T 14-10-2018 IPR018968 Phasin Tharo_0476 ebb0a6ced3d64a0ca6e615e14dfa45c5 193 Pfam PF02325 YGGT family 112 179 1.8E-15 T 14-10-2018 IPR003425 CCB3/YggT GO:0016020 Tharo_0476 ebb0a6ced3d64a0ca6e615e14dfa45c5 193 Pfam PF02325 YGGT family 13 77 8.5E-15 T 14-10-2018 IPR003425 CCB3/YggT GO:0016020 Tharo_2050 4a39030f8c518942e141cb30c846567d 188 Pfam PF08747 Domain of unknown function (DUF1788) 100 173 3.6E-9 T 14-10-2018 IPR014858 Protein of unknown function DUF1788 Tharo_0573 66ec14b09c433b1318c6021be5ba64f6 135 SUPERFAMILY SSF88723 4 128 2.33E-18 T 14-10-2018 IPR029060 PIN-like domain superfamily Tharo_0573 66ec14b09c433b1318c6021be5ba64f6 135 Gene3D G3DSA:3.40.50.1010 3 132 9.7E-11 T 14-10-2018 Tharo_0573 66ec14b09c433b1318c6021be5ba64f6 135 Pfam PF01850 PIN domain 4 126 7.5E-13 T 14-10-2018 IPR002716 PIN domain Tharo_0573 66ec14b09c433b1318c6021be5ba64f6 135 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 132 9.605 T 14-10-2018 IPR022907 VapC family GO:0004540 Tharo_1927 a48b12d7dd3433cba6efb9d133aa35e4 489 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 6.5E-6 T 14-10-2018 Tharo_1927 a48b12d7dd3433cba6efb9d133aa35e4 489 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 308 320 6.5E-6 T 14-10-2018 Tharo_1927 a48b12d7dd3433cba6efb9d133aa35e4 489 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 73 98 6.5E-6 T 14-10-2018 Tharo_1927 a48b12d7dd3433cba6efb9d133aa35e4 489 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 421 440 6.5E-6 T 14-10-2018 Tharo_1927 a48b12d7dd3433cba6efb9d133aa35e4 489 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 13 478 7.0E-136 T 14-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 Tharo_1927 a48b12d7dd3433cba6efb9d133aa35e4 489 Pfam PF00361 Proton-conducting membrane transporter 125 428 8.0E-72 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1927 a48b12d7dd3433cba6efb9d133aa35e4 489 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 6 478 17.93 T 14-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 Tharo_2850 7d165658376702e58ca4c1bd01c65e34 519 Pfam PF03929 PepSY-associated TM region 12 367 3.6E-53 T 14-10-2018 IPR005625 PepSY-associated TM protein Tharo_2960 399c3fa30c58ab863a3f0ba6b1073f96 337 Pfam PF01136 Peptidase family U32 82 336 2.1E-64 T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 Tharo_1782 b9b1976d714374de4514f3b7aabdd898 220 Gene3D G3DSA:2.40.33.20 2 219 7.1E-72 T 14-10-2018 Tharo_1782 b9b1976d714374de4514f3b7aabdd898 220 Pfam PF03473 MOSC domain 48 163 1.6E-20 T 14-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 Tharo_1782 b9b1976d714374de4514f3b7aabdd898 220 SUPERFAMILY SSF50800 3 214 7.85E-67 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily Tharo_2129 320c2c6da3ab3656432e63cc683d8b6d 272 Pfam PF08346 AntA/AntB antirepressor 28 98 2.3E-27 T 14-10-2018 IPR013557 AntA/AntB antirepressor Tharo_1611 2c78e2e313210397fd84d9a70f87eac2 149 Pfam PF04246 Positive regulator of sigma(E), RseC/MucC 1 131 4.9E-19 T 14-10-2018 Tharo_0769 1ca2d5e82142a95e7f0274ac65bffb89 92 Pfam PF15781 ParE-like toxin of type II bacterial toxin-antitoxin system 4 88 6.8E-32 T 14-10-2018 IPR031552 Type II bacterial toxin-antitoxin system, ParE-like toxin Tharo_0769 1ca2d5e82142a95e7f0274ac65bffb89 92 Gene3D G3DSA:3.30.2310.20 1 87 2.5E-6 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_0769 1ca2d5e82142a95e7f0274ac65bffb89 92 SUPERFAMILY SSF143011 2 84 7.46E-5 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_0780 20f09c5b8ce57c07bd2538920d2e9f9f 191 Pfam PF01169 Uncharacterized protein family UPF0016 6 80 3.5E-20 T 14-10-2018 IPR001727 Gdt1 family Tharo_0780 20f09c5b8ce57c07bd2538920d2e9f9f 191 Pfam PF01169 Uncharacterized protein family UPF0016 104 178 2.3E-22 T 14-10-2018 IPR001727 Gdt1 family Tharo_2688 5e6f48634ad8ebb3adfabe4472f59519 73 Pfam PF11127 Protein of unknown function (DUF2892) 2 61 7.2E-14 T 14-10-2018 IPR021309 Protein of unknown function DUF2892 Tharo_1869 9b65add2f2ef3f24d71c081f787b52c2 151 Pfam PF03061 Thioesterase superfamily 22 105 5.0E-13 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 Tharo_1869 9b65add2f2ef3f24d71c081f787b52c2 151 Gene3D G3DSA:3.10.129.10 1 140 7.4E-30 T 14-10-2018 Tharo_1869 9b65add2f2ef3f24d71c081f787b52c2 151 SUPERFAMILY SSF54637 3 138 2.49E-35 T 14-10-2018 IPR029069 HotDog domain superfamily Tharo_2815 9233a2cd6e8b1f3b934aa349b37a9b4d 273 Pfam PF01925 Sulfite exporter TauE/SafE 17 267 2.8E-45 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 Tharo_2565 88543edb32ca9581a16dff45144a4975 178 SUPERFAMILY SSF81342 3 174 2.12E-34 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 Tharo_2565 88543edb32ca9581a16dff45144a4975 178 Pfam PF01292 Prokaryotic cytochrome b561 4 174 3.8E-29 T 14-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 Tharo_1699 a889555269b07c7a8cf9f91d68ab37d5 214 Pfam PF07963 Prokaryotic N-terminal methylation motif 20 42 4.8E-5 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Tharo_1699 a889555269b07c7a8cf9f91d68ab37d5 214 PIRSF PIRSF004525 14 161 1.7E-17 T 14-10-2018 IPR016419 Prepilin peptidase-dependent protein B, predicted Tharo_1699 a889555269b07c7a8cf9f91d68ab37d5 214 PIRSF PIRSF004525 171 213 97.0 T 14-10-2018 IPR016419 Prepilin peptidase-dependent protein B, predicted Tharo_1699 a889555269b07c7a8cf9f91d68ab37d5 214 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 21 42 2.8E-4 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Tharo_1699 a889555269b07c7a8cf9f91d68ab37d5 214 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 21 41 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site Tharo_3459 82388368c2de65673871a310ef158cca 313 Pfam PF11740 Plasmid replication region DNA-binding N-term 7 122 2.7E-18 T 14-10-2018 IPR021104 KfrA, N-terminal DNA-binding domain Tharo_1248 eccc9013e6a944fb0f66f6252480e934 341 Gene3D G3DSA:3.40.190.170 31 338 1.0E-83 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily Tharo_1248 eccc9013e6a944fb0f66f6252480e934 341 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 44 315 1.1E-42 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 Tharo_1248 eccc9013e6a944fb0f66f6252480e934 341 SUPERFAMILY SSF53850 55 251 1.85E-5 T 14-10-2018 Tharo_2760 fb82bec89e94205e7f4bf1e8b7e21238 189 Pfam PF01478 Type IV leader peptidase family 6 119 1.1E-13 T 14-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 Tharo_2503 e9bf1cee7cc6339bd183baad5a9677dc 165 Pfam PF06271 RDD family 26 153 1.2E-17 T 14-10-2018 IPR010432 RDD Tharo_2646 83227418224f962cf6eb641b3340b131 523 Pfam PF13148 Protein of unknown function (DUF3987) 77 440 1.3E-98 T 14-10-2018 IPR025048 Protein of unknown function DUF3987) Tharo_0901 481a45595bf5e290aab292efb32ab951 157 Pfam PF05433 Glycine zipper 2TM domain 65 105 6.0E-8 T 14-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 Tharo_1940 b5e9d188e0467fee06d293486f1db15b 131 Gene3D G3DSA:2.60.120.10 18 126 6.1E-20 T 14-10-2018 IPR014710 RmlC-like jelly roll fold Tharo_1940 b5e9d188e0467fee06d293486f1db15b 131 SUPERFAMILY SSF51182 4 131 2.28E-46 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily Tharo_1940 b5e9d188e0467fee06d293486f1db15b 131 Pfam PF01050 Mannose-6-phosphate isomerase 1 126 1.3E-63 T 14-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 Tharo_2495 e62148f6f0d0f6e4c9f327885f021a09 96 PIRSF PIRSF021239 1 96 1.6E-46 T 14-10-2018 IPR007437 Protein of unknown function DUF486 Tharo_2495 e62148f6f0d0f6e4c9f327885f021a09 96 Pfam PF04342 Putative member of DMT superfamily (DUF486) 1 94 7.2E-40 T 14-10-2018 IPR007437 Protein of unknown function DUF486 Tharo_3258 3dbdff29c2ec0d7bdef597c403424202 234 Gene3D G3DSA:3.40.50.150 6 230 5.4E-23 T 14-10-2018 Tharo_3258 3dbdff29c2ec0d7bdef597c403424202 234 Pfam PF13649 Methyltransferase domain 58 152 5.4E-14 T 14-10-2018 Tharo_3258 3dbdff29c2ec0d7bdef597c403424202 234 SUPERFAMILY SSF53335 13 227 1.88E-27 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_0278 b7d08e298b9aae86f8bd0c70f876fa29 154 Pfam PF11663 Toxin with endonuclease activity, of toxin-antitoxin system 8 144 2.3E-58 T 14-10-2018 IPR021679 Toxin endonuclease, YhaV GO:0004540|GO:0110001 Tharo_0447 4ea6273d47f65dea6d265b3c4665eefd 242 Pfam PF01435 Peptidase family M48 150 241 5.5E-7 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 Tharo_2807 47ea26dc432fad4e960bd63bade8340b 205 Gene3D G3DSA:2.40.50.870 51 202 1.8E-50 T 14-10-2018 Tharo_2807 47ea26dc432fad4e960bd63bade8340b 205 Pfam PF11736 Protein of unknown function (DUF3299) 58 197 1.0E-42 T 14-10-2018 IPR021727 Protein of unknown function DUF3299 Tharo_1977 7ae5701de3fb48d768431d6f71abab19 154 Gene3D G3DSA:3.40.630.30 6 154 1.3E-43 T 14-10-2018 Tharo_1977 7ae5701de3fb48d768431d6f71abab19 154 SUPERFAMILY SSF55729 7 154 1.72E-33 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Tharo_1977 7ae5701de3fb48d768431d6f71abab19 154 Pfam PF00583 Acetyltransferase (GNAT) family 20 128 1.8E-14 T 14-10-2018 IPR000182 GNAT domain Tharo_1977 7ae5701de3fb48d768431d6f71abab19 154 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 15 150 3.9E-36 T 14-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 Tharo_2228 8daf81472be8f1efc68ea432c5fd0592 245 Pfam PF09955 Predicted integral membrane protein (DUF2189) 53 175 2.3E-39 T 14-10-2018 IPR018692 Predicted integral membrane protein DUF2189 Tharo_0183 03d540048de8d83b7489e0f7b56075a2 224 SUPERFAMILY SSF56507 61 192 4.19E-15 T 14-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_0183 03d540048de8d83b7489e0f7b56075a2 224 Gene3D G3DSA:3.40.109.40 24 194 2.9E-13 T 14-10-2018 Tharo_2001 03d540048de8d83b7489e0f7b56075a2 224 SUPERFAMILY SSF56507 61 192 4.19E-15 T 14-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Tharo_2001 03d540048de8d83b7489e0f7b56075a2 224 Gene3D G3DSA:3.40.109.40 24 194 2.9E-13 T 14-10-2018 Tharo_0768 e9a57404ed1f9108697f17f38e80a9f6 69 Pfam PF11903 ParD-like antitoxin of type II bacterial toxin-antitoxin system 5 62 2.7E-18 T 14-10-2018 IPR021831 ParD-like antitoxin of type II bacterial toxin-antitoxin system Tharo_1843 d2bca3754f55068eb1ede93f21e42ad6 262 SUPERFAMILY SSF51695 21 255 8.37E-64 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 Tharo_1843 d2bca3754f55068eb1ede93f21e42ad6 262 Gene3D G3DSA:3.20.20.190 24 251 3.4E-71 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 Tharo_1843 d2bca3754f55068eb1ede93f21e42ad6 262 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 28 254 1.0E-36 T 14-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 Tharo_2600 d1940aef941617fc4bc7ae877a46851a 704 Pfam PF10136 Site-specific recombinase 15 660 3.8E-232 T 14-10-2018 IPR011385 Putative site-specific recombinase Gcr Tharo_2600 d1940aef941617fc4bc7ae877a46851a 704 PIRSF PIRSF015380 7 678 5.9E-168 T 14-10-2018 IPR011385 Putative site-specific recombinase Gcr Tharo_0538 04b1b23a5ca6fa5e913558f7a42e072c 179 Gene3D G3DSA:3.30.70.2060 61 120 1.9E-18 T 14-10-2018 Tharo_0538 04b1b23a5ca6fa5e913558f7a42e072c 179 Pfam PF05573 NosL 22 167 2.8E-55 T 14-10-2018 IPR008719 Nitrous oxide reductase accessory protein NosL Tharo_0538 04b1b23a5ca6fa5e913558f7a42e072c 179 Gene3D G3DSA:3.30.70.2050 121 178 4.7E-12 T 14-10-2018 Tharo_0538 04b1b23a5ca6fa5e913558f7a42e072c 179 SUPERFAMILY SSF160387 61 178 5.23E-38 T 14-10-2018 Tharo_2304 30a190a687ac6c70c092f4222d72a796 244 Pfam PF04172 LrgB-like family 23 236 5.3E-79 T 14-10-2018 IPR007300 CidB/LrgB family Tharo_2460 6c22936484f86d0b4bbc2a9db2003d15 629 SUPERFAMILY SSF48239 220 453 9.1E-7 T 14-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid Tharo_1989 5ab12b2214b215ca155c61de96c05c1e 563 Pfam PF03109 ABC1 family 118 236 6.2E-34 T 14-10-2018 IPR004147 UbiB domain Tharo_1989 5ab12b2214b215ca155c61de96c05c1e 563 SUPERFAMILY SSF56112 101 439 1.31E-28 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily Tharo_3395 b4f9dee7f00a7aa531b2a0adbbeaa90b 256 Pfam PF01925 Sulfite exporter TauE/SafE 12 249 1.3E-40 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 Tharo_0692 3f8981edf1f6bd91e99913c8298078d7 468 TIGRFAM TIGR03755 conj_TIGR03755: integrating conjugative element protein, PFL_4711 family 52 461 4.5E-177 T 14-10-2018 IPR021204 Integrating conjugative element protein, PFL4711 Tharo_0090 8c72e7bd6741a9cf83970ba666fb1494 409 SUPERFAMILY SSF56645 87 310 1.13E-32 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Tharo_0090 8c72e7bd6741a9cf83970ba666fb1494 409 Gene3D G3DSA:2.40.110.20 154 313 7.6E-51 T 14-10-2018 Tharo_0090 8c72e7bd6741a9cf83970ba666fb1494 409 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 204 303 1.4E-15 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Tharo_1560 b85d8805d22085a0e3ba9ff7727536ef 473 Pfam PF04375 HemX, putative uroporphyrinogen-III C-methyltransferase 56 387 8.0E-62 T 14-10-2018 IPR007470 Putative uroporphyrinogen-III C-methyltransferase HemX Tharo_2754 5556302ee33f371da1f507c631f98e5d 140 Pfam PF07811 TadE-like protein 7 49 1.5E-13 T 14-10-2018 IPR012495 TadE-like Tharo_3172 1178d465ab67602595a4290dfcb6345b 123 Pfam PF04134 Protein of unknown function, DUF393 10 122 6.8E-18 T 14-10-2018 IPR007263 Protein of unknown function DUF393 Tharo_1335 dabaa8337640178c3a58f09c863828b3 112 Pfam PF11743 Protein of unknown function (DUF3301) 6 98 4.4E-30 T 14-10-2018 IPR021732 Protein of unknown function DUF3301 Tharo_2871 6cf1dbf8d2c0f637bc1f5aa129f39526 291 Pfam PF03547 Membrane transport protein 151 284 5.6E-11 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 Tharo_2871 6cf1dbf8d2c0f637bc1f5aa129f39526 291 Pfam PF03547 Membrane transport protein 8 142 4.3E-7 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 Tharo_2910 486558ac5c0e62d174eb022d2f5b9e4d 456 Pfam PF07044 Protein of unknown function (DUF1329) 87 450 8.5E-128 T 14-10-2018 IPR010752 Protein of unknown function DUF1329 Tharo_1408 3af4a4710b1c859e4843b7a94131874c 442 Pfam PF07670 Nucleoside recognition 131 227 7.1E-7 T 14-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 Tharo_2119 7b0270cd13c6bf977ffcabf0fc1313f5 431 Pfam PF13252 Protein of unknown function (DUF4043) 61 426 1.0E-108 T 14-10-2018 IPR025267 Protein of unknown function DUF4043 Tharo_2119 7b0270cd13c6bf977ffcabf0fc1313f5 431 TIGRFAM TIGR04387 capsid_maj_N4: major capsid protein, N4-gp56 family 64 343 9.2E-22 T 14-10-2018 Tharo_0650 bfbd0ccb3c5f5f2beed654878fe87ebb 184 Pfam PF11136 Protein of unknown function (DUF2889) 14 137 3.2E-39 T 14-10-2018 IPR021312 Protein of unknown function DUF2889 Tharo_3124 ae51cb08bcff50086aff45d2fd30f9e1 351 Pfam PF02424 ApbE family 40 314 3.1E-68 T 14-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 Tharo_3124 ae51cb08bcff50086aff45d2fd30f9e1 351 Gene3D G3DSA:3.10.520.20 25 344 1.1E-79 T 14-10-2018 Tharo_3124 ae51cb08bcff50086aff45d2fd30f9e1 351 SUPERFAMILY SSF143631 32 339 1.7E-72 T 14-10-2018 IPR003374 ApbE-like superfamily Tharo_3124 ae51cb08bcff50086aff45d2fd30f9e1 351 PIRSF PIRSF006268 6 343 6.5E-80 T 14-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 Tharo_0539 d5e20613df5d53805e4a90589af3deb5 271 Pfam PF12679 ABC-2 family transporter protein 8 271 1.8E-39 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 Tharo_0701 ffd23f128af4d20f5c3aeff86585ed2e 230 TIGRFAM TIGR03746 conj_TIGR03746: integrating conjugative element protein, PFL_4703 family 4 207 4.8E-95 T 14-10-2018 IPR021548 Protein of unknown function DUF2895 Tharo_0701 ffd23f128af4d20f5c3aeff86585ed2e 230 Pfam PF11444 Protein of unknown function (DUF2895) 6 206 8.6E-90 T 14-10-2018 IPR021548 Protein of unknown function DUF2895 Tharo_2296 ec9f58bedfbc235ea245a354129dd549 62 Pfam PF05545 Cbb3-type cytochrome oxidase component FixQ 7 45 2.2E-9 T 14-10-2018 IPR008621 Cbb3-type cytochrome oxidase component Tharo_1364 07321a8ee17b2900a9234d623b9ca2c8 72 SUPERFAMILY SSF64307 5 69 5.23E-9 T 14-10-2018 IPR036868 TusA-like domain superfamily Tharo_1364 07321a8ee17b2900a9234d623b9ca2c8 72 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 6 69 5.9E-17 T 14-10-2018 IPR018720 Domain of unknown function DUF2249 Tharo_1128 104c98b7de7b08422e31b12d1711a277 343 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 30 315 2.7E-56 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 Tharo_1128 104c98b7de7b08422e31b12d1711a277 343 SUPERFAMILY SSF53850 135 273 1.72E-5 T 14-10-2018 Tharo_1128 104c98b7de7b08422e31b12d1711a277 343 Gene3D G3DSA:3.40.190.170 25 341 3.1E-98 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily Tharo_0048 8383606e18fa16cdd43dd292ce7a6e0a 396 PIRSF PIRSF015557 7 393 1.8E-146 T 14-10-2018 IPR016633 Uncharacterised conserved protein UCP015557 Tharo_0048 8383606e18fa16cdd43dd292ce7a6e0a 396 TIGRFAM TIGR03837 efp_adjacent_2: conserved hypothetical protein, PP_1857 family 12 388 2.9E-147 T 14-10-2018 IPR016633 Uncharacterised conserved protein UCP015557 Tharo_0048 8383606e18fa16cdd43dd292ce7a6e0a 396 Pfam PF10093 Uncharacterized protein conserved in bacteria (DUF2331) 12 388 8.3E-144 T 14-10-2018 IPR016633 Uncharacterised conserved protein UCP015557 Tharo_3467 89f39c8cc156ee2338917a103c4f915e 91 Pfam PF17383 Uncharacterized KorC regulated protein A 17 91 2.4E-31 T 14-10-2018 IPR035338 Protein KleA/KleC Tharo_3467 89f39c8cc156ee2338917a103c4f915e 91 ProDom PD019538 PLASMID KLEA KLEC KCRA1 STABLE INHERITANCE KCRB1 17 88 2.0E-23 T 14-10-2018 IPR035338 Protein KleA/KleC Tharo_2413 f2314cdfee818cfcdf4ac09cae190b2c 272 Pfam PF03239 Iron permease FTR1 family 4 256 3.3E-28 T 14-10-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0016020|GO:0033573|GO:0034755 Tharo_2218 f270d7a69d9320416c652ff655cd17fe 392 Pfam PF05762 VWA domain containing CoxE-like protein 184 271 2.1E-10 T 14-10-2018 IPR008912 Uncharacterised protein family CoxE-like Tharo_3111 44dd21ad272877f47fe0e9ed02d90db1 241 Gene3D G3DSA:3.90.1470.10 51 166 3.2E-77 T 14-10-2018 Tharo_3111 44dd21ad272877f47fe0e9ed02d90db1 241 Pfam PF12710 haloacid dehalogenase-like hydrolase 43 198 2.9E-9 T 14-10-2018 Tharo_3111 44dd21ad272877f47fe0e9ed02d90db1 241 Gene3D G3DSA:3.40.50.1000 41 229 3.2E-77 T 14-10-2018 IPR023214 HAD superfamily Tharo_3111 44dd21ad272877f47fe0e9ed02d90db1 241 TIGRFAM TIGR02137 HSK-PSP: phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein 40 236 1.7E-90 T 14-10-2018 IPR011863 Phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 Tharo_3111 44dd21ad272877f47fe0e9ed02d90db1 241 SUPERFAMILY SSF56784 39 236 1.19E-40 T 14-10-2018 IPR036412 HAD-like superfamily Tharo_2211 05c48885971db23515f17f6428bcf654 151 Pfam PF04214 Protein of unknown function, DUF 57 125 5.7E-32 T 14-10-2018 IPR007332 Protein of unknown function DUF411 Tharo_3135 6f9d4c7c04709628a7f82dad490c830a 189 SMART SM01321 20 167 2.1E-22 T 14-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 Tharo_3135 6f9d4c7c04709628a7f82dad490c830a 189 SUPERFAMILY SSF143422 19 172 7.06E-21 T 14-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 Tharo_3135 6f9d4c7c04709628a7f82dad490c830a 189 Gene3D G3DSA:3.30.70.1290 15 183 1.7E-33 T 14-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 Tharo_0871 7d5088cb54c51aa794a46acde296e599 175 PIRSF PIRSF019239 14 175 1.4E-42 T 14-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 Tharo_0871 7d5088cb54c51aa794a46acde296e599 175 Pfam PF01899 Na+/H+ ion antiporter subunit 25 173 8.4E-42 T 14-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 Tharo_0570 82e8dc2a4769313508e2a64e8163bbe3 201 Pfam PF06080 Protein of unknown function (DUF938) 6 200 9.1E-68 T 14-10-2018 IPR010342 Protein of unknown function DUF938 Tharo_0570 82e8dc2a4769313508e2a64e8163bbe3 201 SUPERFAMILY SSF53335 8 198 4.56E-29 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_0570 82e8dc2a4769313508e2a64e8163bbe3 201 Gene3D G3DSA:3.40.50.150 2 199 8.0E-19 T 14-10-2018 Tharo_3394 7e1ce64ebdf69fd7ee779fcfceda2d8c 137 Pfam PF02675 S-adenosylmethionine decarboxylase 14 131 3.8E-25 T 14-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 Tharo_3394 7e1ce64ebdf69fd7ee779fcfceda2d8c 137 SUPERFAMILY SSF56276 11 132 2.71E-25 T 14-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 Tharo_3394 7e1ce64ebdf69fd7ee779fcfceda2d8c 137 Gene3D G3DSA:3.60.90.10 1 136 3.2E-32 T 14-10-2018 Tharo_2272 ca9e3587307bf58dc6455b604bdfcade 113 SUPERFAMILY SSF52091 21 100 6.67E-12 T 14-10-2018 IPR036513 STAS domain superfamily Tharo_2272 ca9e3587307bf58dc6455b604bdfcade 113 Gene3D G3DSA:3.30.750.24 13 111 5.1E-12 T 14-10-2018 IPR036513 STAS domain superfamily Tharo_2272 ca9e3587307bf58dc6455b604bdfcade 113 Pfam PF13466 STAS domain 25 96 1.8E-15 T 14-10-2018 IPR002645 STAS domain Tharo_1381 83518e5291ee51a5af962faa6414fffc 139 SUPERFAMILY SSF88723 1 137 1.07E-29 T 14-10-2018 IPR029060 PIN-like domain superfamily Tharo_1381 83518e5291ee51a5af962faa6414fffc 139 Pfam PF01850 PIN domain 2 127 7.4E-17 T 14-10-2018 IPR002716 PIN domain Tharo_1381 83518e5291ee51a5af962faa6414fffc 139 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 136 12.425 T 14-10-2018 IPR022907 VapC family GO:0004540 Tharo_1381 83518e5291ee51a5af962faa6414fffc 139 Gene3D G3DSA:3.40.50.1010 1 139 1.6E-40 T 14-10-2018 Tharo_0820 84c685d017a4fc5cf4a126230c0d7e31 62 Pfam PF13627 Prokaryotic lipoprotein-attachment site 12 32 3.7E-8 T 14-10-2018 IPR032831 Prokaryotic lipoprotein-attachment site Tharo_3065 75ed135f6bc12d05c845afdde10bca9f 564 Pfam PF06980 Protein of unknown function (DUF1302) 45 564 1.5E-132 T 14-10-2018 IPR010727 Protein of unknown function DUF1302 Tharo_3451 912c8b68dbb70f84164b0e3e35a27f80 634 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 121 621 1.1E-161 T 14-10-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 Tharo_3451 912c8b68dbb70f84164b0e3e35a27f80 634 Gene3D G3DSA:3.40.50.300 356 604 9.5E-44 T 14-10-2018 Tharo_3451 912c8b68dbb70f84164b0e3e35a27f80 634 SUPERFAMILY SSF52540 134 610 2.34E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Tharo_0313 9c39b520f5f3bb4f53ef7788d2fdc2a0 304 Pfam PF13280 WYL domain 122 197 3.7E-11 T 14-10-2018 IPR026881 WYL domain Tharo_0313 9c39b520f5f3bb4f53ef7788d2fdc2a0 304 PIRSF PIRSF015558 1 289 1.1E-85 T 14-10-2018 IPR016634 WYL domain protein, s026 type Tharo_1039 ea7d29d1aef98ce3fdfd698b2a9eeac7 209 Pfam PF00857 Isochorismatase family 22 199 3.2E-35 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 Tharo_1039 ea7d29d1aef98ce3fdfd698b2a9eeac7 209 SUPERFAMILY SSF52499 20 203 1.83E-53 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 Tharo_1039 ea7d29d1aef98ce3fdfd698b2a9eeac7 209 Gene3D G3DSA:3.40.50.850 16 204 6.6E-63 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 Tharo_0723 5b3776185a9da016c73a7d9dda0092c7 275 Pfam PF06067 Domain of unknown function (DUF932) 37 264 1.2E-61 T 14-10-2018 IPR026325 Protein of unknown function DUF932 Tharo_2420 cf19bb65bca37bcea0bb5db8a100701d 166 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 64 165 2.5E-8 T 14-10-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 Tharo_2420 cf19bb65bca37bcea0bb5db8a100701d 166 SUPERFAMILY SSF49503 55 165 6.41E-31 T 14-10-2018 IPR008972 Cupredoxin Tharo_2420 cf19bb65bca37bcea0bb5db8a100701d 166 Gene3D G3DSA:2.60.40.420 27 166 2.7E-29 T 14-10-2018 IPR008972 Cupredoxin Tharo_1802 1a2b952e36dd0b07198d82ea00880e65 95 Gene3D G3DSA:3.30.70.100 2 92 6.7E-24 T 14-10-2018 Tharo_1802 1a2b952e36dd0b07198d82ea00880e65 95 Pfam PF07045 Domain of unknown function (DUF1330) 4 94 1.9E-25 T 14-10-2018 IPR010753 Domain of unknown function DUF1330 Tharo_1802 1a2b952e36dd0b07198d82ea00880e65 95 SUPERFAMILY SSF54909 1 92 3.65E-23 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel Tharo_0722 ceac4c7b54c62c4aceeba98fac234b8c 232 Pfam PF11679 Protein of unknown function (DUF3275) 14 225 4.4E-91 T 14-10-2018 IPR021693 Protein of unknown function DUF3275 Tharo_0384 0bfde435698926034567ad6cb56cd36b 352 Pfam PF14261 Domain of unknown function (DUF4351) 274 334 3.7E-7 T 14-10-2018 IPR025587 Domain of unknown function DUF4351 Tharo_0384 0bfde435698926034567ad6cb56cd36b 352 Pfam PF04754 Putative transposase, YhgA-like 5 173 2.1E-29 T 14-10-2018 IPR006842 Transposase (putative), YhgA-like Tharo_1527 341b9e243bb9b5b22af0e2c27ae6746d 198 Pfam PF06930 Protein of unknown function (DUF1282) 9 180 5.6E-28 T 14-10-2018 IPR009698 Protein of unknown function DUF1282 Tharo_2238 f5768558139fd73608057b17cd95dfea 341 SUPERFAMILY SSF53067 65 158 2.33E-5 T 14-10-2018 Tharo_2018 892e3eb37f2f35bc7d9499915d49e65d 435 Pfam PF13657 HipA N-terminal domain 8 107 3.6E-17 T 14-10-2018 IPR017508 HipA, N-terminal subdomain 1 Tharo_2018 892e3eb37f2f35bc7d9499915d49e65d 435 Pfam PF07804 HipA-like C-terminal domain 148 379 8.8E-54 T 14-10-2018 IPR012893 HipA-like, C-terminal Tharo_2018 892e3eb37f2f35bc7d9499915d49e65d 435 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 6 107 2.4E-16 T 14-10-2018 IPR017508 HipA, N-terminal subdomain 1 Tharo_3001 124f9357e8d06eca7be4bb48d02da703 455 Pfam PF07044 Protein of unknown function (DUF1329) 79 450 2.9E-121 T 14-10-2018 IPR010752 Protein of unknown function DUF1329 Tharo_2633 b842831b25a94b9b5de680d9a8a9f9ab 138 Pfam PF11162 Protein of unknown function (DUF2946) 10 135 2.3E-13 T 14-10-2018 IPR021333 Protein of unknown function DUF2946 Tharo_3332 0e0d3a2afe14857b702b2119dcd87180 341 Pfam PF13280 WYL domain 152 328 4.4E-28 T 14-10-2018 IPR026881 WYL domain Tharo_3464 fe434815c9984d4dc56a6d50d794d2db 80 Pfam PF10959 Protein of unknown function (DUF2761) 5 79 3.3E-35 T 14-10-2018 IPR024249 Protein of unknown function DUF2761 Tharo_3464 fe434815c9984d4dc56a6d50d794d2db 80 ProDom PD029589 PLASMID KLEF KCRB4 STABLE INHERITANCE INITIATION ALTERNATIVE 5 79 3.0E-26 T 14-10-2018 IPR024249 Protein of unknown function DUF2761 Tharo_0463 6156bbbce1f324ae44f60f21dd6a2fb0 188 Pfam PF11748 Protein of unknown function (DUF3306) 5 126 2.3E-32 T 14-10-2018 IPR021735 Protein of unknown function DUF3306 Tharo_2323 a61dbdd8326a7cfbc8f4d67028a7ae9f 179 Pfam PF07813 LTXXQ motif family protein 58 151 6.2E-14 T 14-10-2018 IPR012899 LTXXQ motif family protein GO:0042597 Tharo_1842 94fb464b41a07f721179827305d7802b 493 Pfam PF01936 NYN domain 10 153 1.6E-34 T 14-10-2018 IPR021139 NYN domain, limkain-b1-type Tharo_1842 94fb464b41a07f721179827305d7802b 493 Gene3D G3DSA:3.40.50.1010 4 157 8.1E-38 T 14-10-2018 Tharo_2085 e0b78dede8196ec4077ad21c9e195930 107 Gene3D G3DSA:2.60.300.12 2 107 9.8E-39 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 Tharo_2085 e0b78dede8196ec4077ad21c9e195930 107 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 14-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 Tharo_2085 e0b78dede8196ec4077ad21c9e195930 107 SUPERFAMILY SSF89360 1 96 3.66E-33 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 Tharo_2085 e0b78dede8196ec4077ad21c9e195930 107 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 107 2.1E-38 T 14-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 Tharo_2085 e0b78dede8196ec4077ad21c9e195930 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 5.2E-26 T 14-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 Tharo_2085 e0b78dede8196ec4077ad21c9e195930 107 TIGRFAM TIGR02011 IscA: iron-sulfur cluster assembly protein IscA 3 107 1.0E-57 T 14-10-2018 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0051536|GO:0097428 Tharo_2242 71b924607c5d1e1adaa1447663a961b4 123 Pfam PF12019 Type II transport protein GspH 18 110 4.4E-6 T 14-10-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 Tharo_0375 556973239edb55569d5048d12a1c5351 229 Pfam PF14261 Domain of unknown function (DUF4351) 158 211 3.0E-8 T 14-10-2018 IPR025587 Domain of unknown function DUF4351 Tharo_0348 838c376793d5612ae559399d5c532ed1 159 Gene3D G3DSA:3.30.750.140 13 122 6.6E-33 T 14-10-2018 IPR038610 FliK-like, C-terminal domain superfamily Tharo_0348 838c376793d5612ae559399d5c532ed1 159 Pfam PF02120 Flagellar hook-length control protein FliK 35 115 3.8E-22 T 14-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal Tharo_0348 838c376793d5612ae559399d5c532ed1 159 PRINTS PR01007 Flagellar hook-length control protein signature 48 66 7.9E-17 T 14-10-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 Tharo_0348 838c376793d5612ae559399d5c532ed1 159 PRINTS PR01007 Flagellar hook-length control protein signature 66 81 7.9E-17 T 14-10-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 Tharo_0348 838c376793d5612ae559399d5c532ed1 159 PRINTS PR01007 Flagellar hook-length control protein signature 23 45 7.9E-17 T 14-10-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 Tharo_0348 838c376793d5612ae559399d5c532ed1 159 PRINTS PR01007 Flagellar hook-length control protein signature 81 104 7.9E-17 T 14-10-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 Tharo_1723 edaff30774ccc9d9896b006bdf0cc63f 529 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 28 495 7.8E-138 T 14-10-2018 IPR003846 Uncharacterised protein family UPF0061 Tharo_1723 edaff30774ccc9d9896b006bdf0cc63f 529 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 2 511 43.466 T 14-10-2018 IPR003846 Uncharacterised protein family UPF0061 Tharo_0173 d970c855866f1d53b1071a860b1c3984 427 Pfam PF07044 Protein of unknown function (DUF1329) 59 421 3.1E-124 T 14-10-2018 IPR010752 Protein of unknown function DUF1329 Tharo_0855 9f3165a0e29b8ec9880aab571656c400 131 Pfam PF04138 GtrA-like protein 12 126 1.4E-20 T 14-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 Tharo_1908 44a982cabf017b180825e954cfb07595 120 Gene3D G3DSA:3.40.30.10 1 111 1.9E-41 T 14-10-2018 Tharo_1908 44a982cabf017b180825e954cfb07595 120 Pfam PF06953 Arsenical resistance operon trans-acting repressor ArsD 1 119 9.1E-44 T 14-10-2018 IPR010712 Arsenical-resistance operon trans-acting repressor ArsD GO:0003677|GO:0045892|GO:0046685 Tharo_1863 d83c95acc3397661ac7404d12416fb31 362 Pfam PF11740 Plasmid replication region DNA-binding N-term 8 119 1.9E-25 T 14-10-2018 IPR021104 KfrA, N-terminal DNA-binding domain Tharo_1440 62cdeab5aeffc834f5c8b309b72723c6 298 Pfam PF01136 Peptidase family U32 92 267 5.4E-13 T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 Tharo_1828 90d9bf667362caa2be07acadfc9d9b95 314 Pfam PF02653 Branched-chain amino acid transport system / permease component 29 294 9.7E-23 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Tharo_3142 60994e7b128599ccea05d7920de7035d 126 Pfam PF04343 Protein of unknown function, DUF488 5 115 4.9E-33 T 14-10-2018 IPR007438 Protein of unknown function DUF488 Tharo_0935 3837500246964c1c91f983e94b6a6385 247 Pfam PF01061 ABC-2 type transporter 2 206 1.1E-28 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 Tharo_0935 3837500246964c1c91f983e94b6a6385 247 PRINTS PR00164 ABC-2 type transport system membrane protein signature 128 152 5.2E-5 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 Tharo_0935 3837500246964c1c91f983e94b6a6385 247 PRINTS PR00164 ABC-2 type transport system membrane protein signature 16 37 5.2E-5 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 Tharo_0935 3837500246964c1c91f983e94b6a6385 247 PRINTS PR00164 ABC-2 type transport system membrane protein signature 165 184 5.2E-5 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 Tharo_1424 5bcc88ca330a44ae535c0d2f5767b920 183 Pfam PF06073 Bacterial protein of unknown function (DUF934) 57 149 9.3E-35 T 14-10-2018 IPR008318 Uncharacterised conserved protein UCP030820 Tharo_0426 a9d6db8943d78853c0412dcaaa50e30e 88 Gene3D G3DSA:1.10.260.40 1 64 7.0E-8 T 14-10-2018 Tharo_0837 a0aad9fb68a194a8bdffdb341f87e39c 90 Pfam PF01019 Gamma-glutamyltranspeptidase 45 86 2.6E-16 T 14-10-2018 Tharo_0837 a0aad9fb68a194a8bdffdb341f87e39c 90 SUPERFAMILY SSF56235 23 86 1.43E-20 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Tharo_3356 39d91fd4b900c84530406229a7f9f64f 234 SUPERFAMILY SSF55729 36 174 2.44E-8 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase Tharo_3356 39d91fd4b900c84530406229a7f9f64f 234 Pfam PF12261 Thermostable hemolysin 35 204 6.2E-62 T 14-10-2018 IPR022050 Thermostable hemolysin Tharo_3462 9071d9d5da1da950bf1556b7fb91f4b4 100 Pfam PF16509 TrfB plasmid transcriptional repressor 5 87 1.1E-32 T 14-10-2018 IPR032428 TrfB transcriptional repressor protein Tharo_3462 9071d9d5da1da950bf1556b7fb91f4b4 100 Gene3D G3DSA:1.10.10.2690 1 100 8.3E-36 T 14-10-2018 Tharo_0755 12ed14aa85435791c984a9b2d221cb93 75 Pfam PF11174 Protein of unknown function (DUF2970) 14 69 3.6E-18 T 14-10-2018 IPR021344 Protein of unknown function DUF2970 Tharo_2980 a4fe1108761cf047c99c15427ca15bbf 267 Pfam PF12697 Alpha/beta hydrolase family 25 256 1.2E-24 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Tharo_2980 a4fe1108761cf047c99c15427ca15bbf 267 SUPERFAMILY SSF53474 19 264 2.2E-41 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_2980 a4fe1108761cf047c99c15427ca15bbf 267 Gene3D G3DSA:3.40.50.1820 10 265 1.1E-39 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold Tharo_2665 4d99cf9ed2d8d05616d90c145775c26f 422 Pfam PF04285 Protein of unknown function (DUF444) 4 419 1.2E-177 T 14-10-2018 IPR006698 Uncharacterised protein family UPF0229 Tharo_2665 4d99cf9ed2d8d05616d90c145775c26f 422 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 1 422 38.378 T 14-10-2018 IPR006698 Uncharacterised protein family UPF0229 Tharo_2132 99379b553a88e854e266632ef92c7a3b 86 Pfam PF01402 Ribbon-helix-helix protein, copG family 24 56 3.7E-6 T 14-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 Tharo_3298 acea747fc2096242d974511f3c7655c0 324 Gene3D G3DSA:3.20.20.70 8 316 4.8E-64 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Tharo_3298 acea747fc2096242d974511f3c7655c0 324 SUPERFAMILY SSF51412 10 309 7.02E-51 T 14-10-2018 Tharo_3298 acea747fc2096242d974511f3c7655c0 324 Pfam PF03060 Nitronate monooxygenase 94 307 2.4E-21 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 Tharo_0688 9f141bdb66310632f874a91c88a95858 152 Pfam PF11663 Toxin with endonuclease activity, of toxin-antitoxin system 8 144 4.2E-58 T 14-10-2018 IPR021679 Toxin endonuclease, YhaV GO:0004540|GO:0110001 Tharo_3311 d698119c9b467b837034bd5dfe18bb17 266 Pfam PF12787 EcsC protein family 69 241 3.9E-33 T 14-10-2018 IPR024787 EcsC protein Tharo_2166 3b77c37a8215e2eb7391d61b6f24a7c4 242 SUPERFAMILY SSF53335 68 203 2.75E-15 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_2166 3b77c37a8215e2eb7391d61b6f24a7c4 242 Pfam PF08241 Methyltransferase domain 68 116 2.0E-7 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 Tharo_2166 3b77c37a8215e2eb7391d61b6f24a7c4 242 Gene3D G3DSA:3.40.50.150 14 183 1.0E-14 T 14-10-2018 Tharo_2867 ebed52a8ea20262986301b381d6199da 74 Pfam PF13711 Domain of unknown function (DUF4160) 6 62 4.6E-9 T 14-10-2018 IPR025427 Protein of unknown function DUF4160 Tharo_3074 eb48ac9c7b6ded5103d077e705fbd967 190 Pfam PF13526 Protein of unknown function (DUF4125) 4 182 1.0E-55 T 14-10-2018 IPR025191 Protein of unknown function DUF4125 Tharo_0833 618243d1052e72bde41fbd968efe703f 320 Pfam PF03547 Membrane transport protein 166 305 1.8E-7 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 Tharo_0833 618243d1052e72bde41fbd968efe703f 320 Pfam PF03547 Membrane transport protein 10 148 1.5E-15 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 Tharo_3042 d69f31e9d614802ec5f0a96636cc5d6c 94 Gene3D G3DSA:3.30.2310.20 1 93 3.6E-22 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_3042 d69f31e9d614802ec5f0a96636cc5d6c 94 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 92 3.1E-14 T 14-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Tharo_2131 99935255ea21953966902c3b3f90854b 96 Pfam PF14384 BrnA antitoxin of type II toxin-antitoxin system 13 77 2.1E-11 T 14-10-2018 IPR025528 BrnA antitoxin of type II toxin-antitoxin system Tharo_3465 69b4630b78b8982aa2b531bac6b5214c 110 ProDom PD030350 PLASMID KLEE KCRB3 STABLE INHERITANCE MEMBRANE TRANSMEMBRANE 1 110 1.0E-24 T 14-10-2018 IPR035362 Protein KleE Tharo_3465 69b4630b78b8982aa2b531bac6b5214c 110 Pfam PF17394 Uncharacterized KleE stable inheritance protein 1 110 1.7E-48 T 14-10-2018 IPR035362 Protein KleE Tharo_0466 6a781b1f493d8284bc774b7dffe2f59f 68 PIRSF PIRSF036704 1 68 2.2E-15 T 14-10-2018 IPR014177 Putative formate dehydrogenase, TAT signal-containing Tharo_0742 411337e76679e0fef019b5cda00a0ff1 70 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 12 62 2.3E-24 T 14-10-2018 IPR010260 DNA-binding transcriptional activator AlpA Tharo_2544 f6357de29cf06e2b549192150daa1087 568 Pfam PF02538 Hydantoinase B/oxoprolinase 11 534 7.6E-138 T 14-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 Tharo_0878 696fbcd691d1dfd9699ac7c2176ee3e6 399 Pfam PF12704 MacB-like periplasmic core domain 21 242 2.6E-33 T 14-10-2018 IPR025857 MacB-like periplasmic core domain Tharo_0878 696fbcd691d1dfd9699ac7c2176ee3e6 399 Pfam PF02687 FtsX-like permease family 304 391 1.3E-10 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Tharo_1220 90088393e563da8a06f6c967aa48eae8 80 Pfam PF04226 Transglycosylase associated protein 34 80 1.7E-12 T 14-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 Tharo_3069 cf075333e7cc341d7b63ab7cb71d9c1d 57 Gene3D G3DSA:2.30.30.1070 1 57 1.7E-28 T 14-10-2018 IPR038640 Benzylsuccinate synthase gamma subunit superfamily KEGG: 00623+4.1.99.11|MetaCyc: PWY-81 Tharo_3069 cf075333e7cc341d7b63ab7cb71d9c1d 57 Pfam PF08201 BssC/TutF protein 1 56 3.8E-30 T 14-10-2018 IPR013161 Benzylsuccinate synthase gamma subunit KEGG: 00623+4.1.99.11|MetaCyc: PWY-81 Tharo_1943 f8de1bb7b512e5ae14f24981ec1b237a 107 Pfam PF01934 Protein of unknown function DUF86 15 93 7.7E-17 T 14-10-2018 IPR008201 Protein of unknown function DUF86 Tharo_2581 27d0431ed1839ed4833b1723b56ae529 350 SUPERFAMILY SSF51430 6 344 1.96E-102 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Tharo_2581 27d0431ed1839ed4833b1723b56ae529 350 Gene3D G3DSA:3.20.20.100 6 350 1.1E-118 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Tharo_2581 27d0431ed1839ed4833b1723b56ae529 350 Pfam PF00248 Aldo/keto reductase family 21 340 6.3E-69 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain Tharo_0705 96da27c03b75aa4a7fc3420b47400dea 127 TIGRFAM TIGR01690 ICE_RAQPRD: integrative conjugative element protein, RAQPRD family 17 110 2.8E-33 T 14-10-2018 IPR019110 Uncharacterised protein family, RAQPRD Tharo_0705 96da27c03b75aa4a7fc3420b47400dea 127 Pfam PF09686 Plasmid protein of unknown function (Plasmid_RAQPRD) 35 109 3.5E-26 T 14-10-2018 IPR019110 Uncharacterised protein family, RAQPRD Tharo_1991 c5f77754d1881166a77a04dbc6f96fd7 102 Pfam PF04341 Protein of unknown function, DUF485 11 98 1.2E-35 T 14-10-2018 IPR007436 Protein of unknown function DUF485 Tharo_0268 9a2adfd42e898cb78b2d90ec9eaa804a 192 Gene3D G3DSA:1.10.8.640 47 130 1.4E-31 T 14-10-2018 IPR038297 CcmH/CycL/Ccl2/NrfF domain superfamily Tharo_0268 9a2adfd42e898cb78b2d90ec9eaa804a 192 Pfam PF03918 Cytochrome C biogenesis protein 48 175 5.2E-50 T 14-10-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family Tharo_1075 798fe71d94288487df1dd215db23159b 181 Pfam PF07209 Protein of unknown function (DUF1415) 4 171 3.7E-66 T 14-10-2018 IPR009858 Protein of unknown function DUF1415 Tharo_3162 c3116e7c217d94061071d8e3233fa6b2 501 SUPERFAMILY SSF81442 14 485 1.26E-61 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_3162 c3116e7c217d94061071d8e3233fa6b2 501 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 18 464 8.9E-51 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_3162 c3116e7c217d94061071d8e3233fa6b2 501 Gene3D G3DSA:1.20.210.10 11 497 4.2E-70 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Tharo_0377 e5ea50a6979246a24b7390e9c581a320 97 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 4 92 1.4E-24 T 14-10-2018 IPR009241 Toxin HigB-like Tharo_0383 b4f6dd6001f402bf21cac78a7b5c7181 60 Gene3D G3DSA:3.30.920.30 2 59 3.0E-19 T 14-10-2018 IPR038570 HicA superfamily Tharo_0383 b4f6dd6001f402bf21cac78a7b5c7181 60 SUPERFAMILY SSF54786 2 55 2.71E-11 T 14-10-2018 Tharo_0383 b4f6dd6001f402bf21cac78a7b5c7181 60 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 8 55 9.7E-13 T 14-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 Tharo_2195 c72d096f680ec7322adfa9be2cacfeee 202 Pfam PF01618 MotA/TolQ/ExbB proton channel family 68 186 1.6E-31 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel Tharo_0683 8efe2831c50a23d227fcfe9c1657db08 71 Pfam PF03050 Transposase IS66 family 14 59 5.1E-9 T 14-10-2018 IPR004291 Transposase, IS66 Tharo_0122 bf52de20313cdf83cc04930442f20d2f 140 Gene3D G3DSA:3.30.2020.30 4 103 8.5E-28 T 14-10-2018 IPR038492 GBBH-like, N-terminal domain superfamily Reactome: R-HSA-71262 Tharo_0122 bf52de20313cdf83cc04930442f20d2f 140 Pfam PF06155 Protein of unknown function (DUF971) 15 98 2.5E-28 T 14-10-2018 IPR010376 Gamma-butyrobetaine hydroxylase-like, N-terminal Reactome: R-HSA-71262 Tharo_2303 25107626aafcf5444702ded7c0b4b099 119 Pfam PF03788 LrgA family 12 104 1.3E-28 T 14-10-2018 IPR005538 LrgA/CidA family GO:0016021 Tharo_1083 e3cb2ddc89506676c681766d547b3f75 432 SUPERFAMILY SSF53335 124 428 2.37E-72 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Tharo_1083 e3cb2ddc89506676c681766d547b3f75 432 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 239 249 2.7E-28 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Tharo_1083 e3cb2ddc89506676c681766d547b3f75 432 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 411 428 2.7E-28 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Tharo_1083 e3cb2ddc89506676c681766d547b3f75 432 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 308 320 2.7E-28 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Tharo_1083 e3cb2ddc89506676c681766d547b3f75 432 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 210 224 2.7E-28 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Tharo_1083 e3cb2ddc89506676c681766d547b3f75 432 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 358 374 2.7E-28 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Tharo_1083 e3cb2ddc89506676c681766d547b3f75 432 Gene3D G3DSA:3.40.50.150 126 428 1.9E-81 T 14-10-2018 Tharo_1083 e3cb2ddc89506676c681766d547b3f75 432 Pfam PF01189 16S rRNA methyltransferase RsmB/F 229 426 2.9E-50 T 14-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 Tharo_0950 1c662c03dbc4a6ef62127840b7819fc9 54 Gene3D G3DSA:3.30.2310.20 1 54 2.1E-6 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_0950 1c662c03dbc4a6ef62127840b7819fc9 54 SUPERFAMILY SSF143011 2 51 4.51E-6 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_1749 1d64a5115eb2b73e030654b1816648d3 352 Gene3D G3DSA:3.30.70.3460 74 159 1.9E-16 T 14-10-2018 Tharo_1749 1d64a5115eb2b73e030654b1816648d3 352 Gene3D G3DSA:3.30.70.3460 216 351 3.5E-38 T 14-10-2018 Tharo_1855 01aa9ccabb772638fb214a35420044a7 115 ProDom PD074011 PRECURSOR SIGNAL RESISTANCE CZCI ZINC COBALT-ZINC-CADMIUM SYSTEM COBALT CATION CADMIUM 1 111 5.0E-20 T 14-10-2018 IPR020487 Cobalt/zinc/cadmium resistance protein CzcI Tharo_0070 5b3a48aa38b97b6f11a068467f40864c 113 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 107 1.8E-25 T 14-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like Tharo_3097 369f3e80ff93af6770c8b5101a300bd8 289 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 276 1.2E-40 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Tharo_3287 cbbbd6c1a34718385f5deaf9522d38ac 54 TIGRFAM TIGR04164 cobo_pep: modified peptide precursor CbpA 30 52 5.6E-15 T 14-10-2018 IPR026421 Modified peptide precursor CbpA Tharo_2603 3921fa83f3eff8ebcbafd11829c06148 92 Gene3D G3DSA:3.30.2310.20 1 92 2.7E-38 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_2603 3921fa83f3eff8ebcbafd11829c06148 92 Pfam PF05015 RelE-like toxin of type II toxin-antitoxin system HigB 3 92 1.6E-28 T 14-10-2018 IPR007711 Toxin HigB-1 Tharo_2603 3921fa83f3eff8ebcbafd11829c06148 92 SUPERFAMILY SSF143011 1 92 9.02E-16 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Tharo_1498 c80cb7bf28cf3fced321d71df79e13f7 192 Gene3D G3DSA:3.10.450.160 73 190 1.2E-8 T 14-10-2018 Tharo_1498 c80cb7bf28cf3fced321d71df79e13f7 192 Pfam PF11776 Nickel/cobalt transporter regulator 156 184 1.7E-5 T 14-10-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB Tharo_3405 0150502ddf115f3b002694647f5b37a6 407 Pfam PF07042 TrfA protein 130 407 2.7E-172 T 14-10-2018 IPR010751 Plasmid replication initiator protein TrfA Tharo_0660 613927228f05da6cce8b4fb9f44edafe 215 SUPERFAMILY SSF53850 12 211 1.09E-25 T 14-10-2018 Tharo_0660 613927228f05da6cce8b4fb9f44edafe 215 Gene3D G3DSA:3.40.190.10 83 183 1.1E-24 T 14-10-2018 Tharo_0660 613927228f05da6cce8b4fb9f44edafe 215 Gene3D G3DSA:3.40.190.10 14 82 1.1E-24 T 14-10-2018 Tharo_0660 613927228f05da6cce8b4fb9f44edafe 215 Pfam PF03466 LysR substrate binding domain 13 191 1.5E-24 T 14-10-2018 IPR005119 LysR, substrate-binding Tharo_1181 3b0488232913e56722ee36db8f7004f3 42 Pfam PF08085 Entericidin EcnA/B family 21 40 4.6E-11 T 14-10-2018 IPR012556 Entericidin A/B GO:0009636|GO:0016020 Tharo_0204 5fb2a53a388efe6e3d8ffb0fadcce09d 1016 Pfam PF00589 Phage integrase family 498 634 4.9E-6 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Tharo_0204 5fb2a53a388efe6e3d8ffb0fadcce09d 1016 SUPERFAMILY SSF56349 384 639 2.69E-13 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Tharo_1108 c3590a94ee2f0345dfd758d219130d8e 159 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 26 155 2.6E-22 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ Tharo_0751 4aafc51712aefb375364ed2cf314a90e 537 Pfam PF02690 Na+/Pi-cotransporter 1 136 1.2E-37 T 14-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 Tharo_0751 4aafc51712aefb375364ed2cf314a90e 537 Pfam PF02690 Na+/Pi-cotransporter 162 237 8.5E-8 T 14-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 Tharo_0316 518392a4d5981e9f32c086b32263b1ad 112 Pfam PF05717 IS66 Orf2 like protein 6 102 1.7E-35 T 14-10-2018 IPR008878 Transposase IS66, Orf2 Tharo_0724 b264ed2b9c16f9be21315e5c53d09a32 304 Pfam PF12101 Protein of unknown function (DUF3577) 132 257 3.2E-47 T 14-10-2018 IPR021960 Protein of unknown function DUF3577 Tharo_0724 b264ed2b9c16f9be21315e5c53d09a32 304 Pfam PF12101 Protein of unknown function (DUF3577) 5 120 4.0E-36 T 14-10-2018 IPR021960 Protein of unknown function DUF3577 Tharo_0978 16f7fc97275ee0f569336f9a5889fcb9 221 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 19 215 2.7E-42 T 14-10-2018 IPR006214 Bax inhibitor 1-related Tharo_0963 5814d845ab082f44464ad9383e4723f7 162 Pfam PF05258 Protein of unknown function (DUF721) 33 107 1.1E-13 T 14-10-2018 IPR007922 Protein of unknown function DUF721/UPF0232 Tharo_2136 d33dc4ce00360d611afdf393a6f47eb4 87 Pfam PF01402 Ribbon-helix-helix protein, copG family 25 54 9.4E-6 T 14-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 Tharo_0764 ea1f5b23822d0624a0c0e2e8b5f2e5c7 71 SUPERFAMILY SSF54786 12 60 5.49E-5 T 14-10-2018 Tharo_3077 b02d884b9af50e9a4a0a43311da336c1 307 Pfam PF13228 Domain of unknown function (DUF4037) 125 225 1.9E-36 T 14-10-2018 IPR025117 Domain of unknown function DUF4037 Tharo_0245 574ac7a650f8134d36d23763da607cea 145 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 10 135 1.8E-19 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ Tharo_0029 6527cdfa79132a8e12836d574fd18d48 130 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 51 92 1.3E-4 T 14-10-2018 IPR018660 C-type lysozyme inhibitor Tharo_2909 01b89ecb2e77610630ccf469e59604c2 561 Pfam PF06980 Protein of unknown function (DUF1302) 41 561 3.6E-132 T 14-10-2018 IPR010727 Protein of unknown function DUF1302 Tharo_1598 98163e487387efaa09c5b4a387279d44 165 Pfam PF02620 Uncharacterized ACR, COG1399 58 158 1.2E-14 T 14-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD Tharo_1522 739498b36bda7a0115286433ca7e9fb0 392 Pfam PF02646 RmuC family 102 378 1.1E-61 T 14-10-2018 IPR003798 DNA recombination RmuC Tharo_3448 5ff8aab01c413382b027c84b39ce042b 127 PIRSF PIRSF017849 1 127 1.8E-47 T 14-10-2018 IPR016703 Conjugal transfer, TraD, beta/gamma-type Tharo_1465 17613c6dc8a5212e6c3700ab04cff9c3 119 Pfam PF03692 Putative zinc- or iron-chelating domain 6 98 1.1E-8 T 14-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein Tharo_2107 fc59ba9f1543b3a9366b5bc11657be18 98 Pfam PF16080 Bacteriophage holin family HP1 3 56 1.8E-9 T 14-10-2018 IPR032118 Bacteriophage holin HP1 family Tharo_2761 2e427e17facc9e487fb064e93bce5bbc 53 Pfam PF04964 Flp/Fap pilin component 8 53 3.2E-19 T 14-10-2018 IPR007047 Flp/Fap pilin component Tharo_2585 bc55e8c317e66e40d8dc41b6baa7df46 101 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 7 91 3.6E-30 T 14-10-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 Tharo_0772 446e3bc8ac04b7f0a9a7dbed737a497b 153 Pfam PF05425 Copper resistance protein D 48 147 2.2E-12 T 14-10-2018 IPR008457 Copper resistance protein D GO:0016021 Tharo_3203 4dbab28153cd9bb8870e1cd34d5ce575 290 PIRSF PIRSF026649 1 290 2.2E-92 T 14-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 Tharo_3203 4dbab28153cd9bb8870e1cd34d5ce575 290 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 4 281 2.5E-64 T 14-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 Tharo_0759 3d1a7bed0cf937c1311384f938678687 402 Pfam PF02628 Cytochrome oxidase assembly protein 43 370 9.7E-76 T 14-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 Tharo_0699 b1a11e5f845f092b35e70c69cbc443e6 469 TIGRFAM TIGR03752 conj_TIGR03752: integrating conjugative element protein, PFL_4705 family 2 459 4.5E-184 T 14-10-2018 IPR021207 Integrating conjugative element protein, PFL4705 Tharo_0380 303df29eec13839b5ac8ec56ecfd8089 101 SUPERFAMILY SSF46785 31 81 4.05E-8 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Tharo_0380 303df29eec13839b5ac8ec56ecfd8089 101 Gene3D G3DSA:1.10.10.10 22 87 3.7E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Tharo_1494 669e89db97cfe80d8f3019aed1b7d590 168 TIGRFAM TIGR01841 phasin: phasin family protein 27 112 5.9E-15 T 14-10-2018 IPR010127 Phasin, subfamily 1 Tharo_1494 669e89db97cfe80d8f3019aed1b7d590 168 Pfam PF09361 Phasin protein 6 104 1.8E-25 T 14-10-2018 IPR018968 Phasin Tharo_0214 6b566acb94491586fb608e87fd882f77 81 Pfam PF07362 Post-segregation antitoxin CcdA 11 81 1.2E-29 T 14-10-2018 IPR009956 Post-segregation antitoxin CcdA Tharo_1746 866daf3db7489719af2b67c2cfccff18 108 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 34 107 3.1E-6 T 14-10-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 Tharo_1746 866daf3db7489719af2b67c2cfccff18 108 SUPERFAMILY SSF49503 9 107 3.88E-23 T 14-10-2018 IPR008972 Cupredoxin Tharo_1746 866daf3db7489719af2b67c2cfccff18 108 Gene3D G3DSA:2.60.40.420 16 107 7.2E-20 T 14-10-2018 IPR008972 Cupredoxin Tharo_2226 182109718cab83b98ca8ce88ec3799b0 71 Pfam PF04325 Protein of unknown function (DUF465) 16 62 2.7E-15 T 14-10-2018 IPR007420 Protein of unknown function DUF465 Tharo_2226 182109718cab83b98ca8ce88ec3799b0 71 Gene3D G3DSA:1.20.58.660 1 68 1.0E-7 T 14-10-2018 Tharo_3039 2e094776e9e05408444efad720c450a0 313 Pfam PF05982 Na+-dependent bicarbonate transporter superfamily 7 308 6.4E-105 T 14-10-2018 IPR010293 Na+-dependent bicarbonate transporter superfamily Tharo_1000 ac2ac8044e0982d65c6c526e02ee0e19 61 Pfam PF09838 Uncharacterized protein conserved in bacteria (DUF2065) 5 59 6.9E-22 T 14-10-2018 IPR019201 Protein of unknown function DUF2065 Tharo_1815 d75edc4549b1da1a7a85f093aa5f4fbd 346 Pfam PF02653 Branched-chain amino acid transport system / permease component 65 328 6.5E-33 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Tharo_3420 5360c3ab7b9af96d02df08db76b533d2 638 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 67 282 6.3E-43 T 14-10-2018 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 Tharo_3420 5360c3ab7b9af96d02df08db76b533d2 638 TIGRFAM TIGR02783 TrbL_P: P-type conjugative transfer protein TrbL 32 342 2.1E-76 T 14-10-2018 IPR014150 Conjugal transfer, TrbL Tharo_2995 83b565cdef08d605b526ab88ce3d5542 113 Pfam PF08895 Domain of unknown function (DUF1840) 1 111 1.6E-32 T 14-10-2018 IPR014991 Protein of unknown function DUF1840 Tharo_0036 233d9fdad7e010bf5ee1ba2dc85bff74 76 Pfam PF11391 Protein of unknown function (DUF2798) 11 68 2.7E-19 T 14-10-2018 IPR021529 Protein of unknown function DUF2798 Tharo_3096 ffe040048195218600350d776cf0dc28 315 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 289 1.6E-45 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Tharo_0304 bf60c941f21526e22bc35ea39377505e 485 TIGRFAM TIGR03752 conj_TIGR03752: integrating conjugative element protein, PFL_4705 family 2 475 1.4E-185 T 14-10-2018 IPR021207 Integrating conjugative element protein, PFL4705 Tharo_0131 23c2c8714f4423d5b952e8fd5259dd68 147 Gene3D G3DSA:1.20.120.330 21 140 4.8E-6 T 14-10-2018 Tharo_3452 d62a07c4b526d9e2a38b9dcc61d72692 733 Pfam PF03432 Relaxase/Mobilisation nuclease domain 5 244 1.2E-57 T 14-10-2018 IPR005094 Endonuclease relaxase, MobA/VirD2 Tharo_1137 307d8321978c9ca6621ba704eee7c3d8 155 Pfam PF16155 Domain of unknown function (DUF4863) 9 152 1.2E-56 T 14-10-2018 IPR032345 Protein of unknown function DUF4863 Tharo_1365 d74f9d28d4622894dd320aada5a3f778 152 Pfam PF01814 Hemerythrin HHE cation binding domain 4 126 6.4E-22 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 Tharo_1365 d74f9d28d4622894dd320aada5a3f778 152 Gene3D G3DSA:1.20.120.520 1 145 2.5E-22 T 14-10-2018 Tharo_3106 23fce2828f95df38cc2a0820665485bf 96 Pfam PF11854 Putative outer membrane beta-barrel porin, MtrB/PioB 30 95 2.0E-8 T 14-10-2018 IPR020016 Decahaem-associated outer membrane protein, MtrB/PioB Tharo_1923 01bfbc135d95ef240e8035e7bdc6d8fc 201 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 19 165 1.7E-40 T 14-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Tharo_1923 01bfbc135d95ef240e8035e7bdc6d8fc 201 Gene3D G3DSA:1.20.120.1200 4 167 9.1E-47 T 14-10-2018 Tharo_0689 e9ffa272bb654575ce432ecfa7af2673 127 Pfam PF12553 Protein of unknown function (DUF3742) 4 110 1.9E-40 T 14-10-2018 IPR022213 Protein of unknown function DUF3742 Tharo_3415 1ea6719f62064ac50c99bb5a8aed0be4 151 Pfam PF07283 Conjugal transfer protein TrbH 32 151 4.7E-54 T 14-10-2018 IPR010837 Conjugal transfer, TrbH Tharo_1955 ff1259e58cf614f8f9ffe1d6cf24133e 140 Pfam PF10116 Protein required for attachment to host cells 1 134 1.1E-38 T 14-10-2018 IPR019291 Host attachment protein Tharo_0854 3051d10acf83bf8077187f25bc56ac1f 523 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 86 222 2.3E-6 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like Tharo_2934 d371c1132d163a57ad1cfd2a92c6c374 64 Pfam PF06945 Protein of unknown function (DUF1289) 7 31 3.8E-9 T 14-10-2018 IPR010710 Protein of unknown function DUF1289 Tharo_0967 884d26d32435cb566f910afbeecd9a93 105 Pfam PF10084 Uncharacterized protein conserved in bacteria (DUF2322) 3 100 5.3E-43 T 14-10-2018 IPR016755 Uncharacterised conserved protein UCP019302 Tharo_0967 884d26d32435cb566f910afbeecd9a93 105 PIRSF PIRSF019302 1 105 2.4E-46 T 14-10-2018 IPR016755 Uncharacterised conserved protein UCP019302 Tharo_0986 8362ed8aa2ce1463bb4f19a1792190cd 217 Pfam PF09335 SNARE associated Golgi protein 49 174 1.2E-24 T 14-10-2018 IPR032816 SNARE associated Golgi protein Tharo_0675 ce0dee3802004cc16389ff5951e779e7 153 Pfam PF09361 Phasin protein 11 102 7.7E-8 T 14-10-2018 IPR018968 Phasin Tharo_0373 81a12b5122da943636932504614c8823 110 Pfam PF05717 IS66 Orf2 like protein 1 96 7.4E-33 T 14-10-2018 IPR008878 Transposase IS66, Orf2 Tharo_3236 81a12b5122da943636932504614c8823 110 Pfam PF05717 IS66 Orf2 like protein 1 96 7.4E-33 T 14-10-2018 IPR008878 Transposase IS66, Orf2 Tharo_1540 81a12b5122da943636932504614c8823 110 Pfam PF05717 IS66 Orf2 like protein 1 96 7.4E-33 T 14-10-2018 IPR008878 Transposase IS66, Orf2 Tharo_1754 1ec54e523585a1c8247bdef12790fd23 395 Pfam PF05940 NnrS protein 21 389 3.0E-111 T 14-10-2018 IPR010266 NnrS Tharo_1091 69142478b9da37fdaa11c83ccc4d981d 66 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 1 42 1.5E-16 T 14-10-2018 IPR019239 Bacterial antitoxin of type II TA system, VapB Tharo_0586 f7847ce0a6e13423828d243d517c941a 608 Pfam PF09823 Domain of unknown function (DUF2357) 126 226 6.2E-6 T 14-10-2018 IPR018633 Domain of unknown function DUF2357 Tharo_2062 0760afb4075fb7e29a50d7ad2f21881f 273 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 229 255 - T 14-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 Tharo_2062 0760afb4075fb7e29a50d7ad2f21881f 273 Pfam PF01148 Cytidylyltransferase family 3 267 1.8E-54 T 14-10-2018 Tharo_1864 e8460a9ec8e65d748d8b07775750fe96 338 Pfam PF02754 Cysteine-rich domain 220 304 5.9E-11 T 14-10-2018 IPR004017 Cysteine-rich domain Tharo_1864 e8460a9ec8e65d748d8b07775750fe96 338 Pfam PF02754 Cysteine-rich domain 93 172 3.8E-10 T 14-10-2018 IPR004017 Cysteine-rich domain Tharo_2838 031efe68ebb80b766c5396857892b66d 252 Pfam PF01618 MotA/TolQ/ExbB proton channel family 92 212 1.6E-36 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel Tharo_0273 287987853b1a9937ac83accc65923816 300 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 10 210 8.8E-41 T 14-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system Tharo_1429 64440c31984a29ad7c7980c1cd72af8d 97 Pfam PF05717 IS66 Orf2 like protein 6 95 1.8E-21 T 14-10-2018 IPR008878 Transposase IS66, Orf2 Tharo_3316 413cb99ea763388a450df488d62990f7 126 Pfam PF11162 Protein of unknown function (DUF2946) 10 123 7.7E-13 T 14-10-2018 IPR021333 Protein of unknown function DUF2946 Tharo_3325 6b2b88d0656f0b37e98011be1bef888e 225 SUPERFAMILY SSF48150 36 185 1.96E-7 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 Tharo_0282 1efb4e30b52272092a48a52d15c6ab31 442 TIGRFAM TIGR03755 conj_TIGR03755: integrating conjugative element protein, PFL_4711 family 27 437 2.1E-176 T 14-10-2018 IPR021204 Integrating conjugative element protein, PFL4711 Tharo_0525 97a459e2d96d5c0f109c9c3b9d72697b 157 Pfam PF13511 Domain of unknown function (DUF4124) 11 69 1.5E-11 T 14-10-2018 IPR025392 Domain of unknown function DUF4124 Tharo_2832 9ba08951eaca7ada4f2be2b61beb2bab 403 SUPERFAMILY SSF56935 23 403 1.04E-29 T 14-10-2018 Tharo_2832 9ba08951eaca7ada4f2be2b61beb2bab 403 Gene3D G3DSA:2.40.160.10 118 387 1.5E-8 T 14-10-2018 IPR023614 Porin domain superfamily Tharo_3265 762781afdc6f1464541ef0437a107d01 646 Pfam PF01757 Acyltransferase family 9 330 3.9E-25 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 Tharo_2755 a514bef0693e03567e2e7e3105984492 412 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 13 58 6.3E-14 T 14-10-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal Tharo_0497 37688feca47ed867a2cf9082d30e2946 173 Pfam PF10649 Protein of unknown function (DUF2478) 6 165 5.2E-53 T 14-10-2018 IPR018912 Protein of unknown function DUF2478 Tharo_0096 ca1b5d05953b2375d6416b7cfbe2aaf8 300 Pfam PF04976 DMSO reductase anchor subunit (DmsC) 28 147 3.2E-7 T 14-10-2018 IPR007059 DMSO reductase anchor subunit (DmsC) GO:0016021|GO:0019645 Tharo_0234 3c0420e6293437b236ed3c504c2e4694 67 Pfam PF14070 Putative motility protein 10 66 1.4E-10 T 14-10-2018 IPR025906 Putative motility protein