locus-tag	class	description
CCZ27_00005	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
CCZ27_00010	ENOG4105T95	Thiol disulfide interChange protein
CCZ27_00015	ENOG4105CA3	membrane-bound lytic murein transglycosylase
CCZ27_00025	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CCZ27_00030	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
CCZ27_00035	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
CCZ27_00040	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CCZ27_00050	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CCZ27_00055	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
CCZ27_00060	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CCZ27_00065	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CCZ27_00070	ENOG4105CUX	Signal transduction histidine kinase
CCZ27_00080	ENOG4105C5F	glutamine synthetase
CCZ27_00100	ENOG4105X23	Endonuclease Exonuclease phosphatase
CCZ27_00105	ENOG4105DZQ	phospholipase D Transphosphatidylase
CCZ27_00110	ENOG4105K4P	CoA-binding domain protein
CCZ27_00115	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
CCZ27_00165	ENOG4108T0W	nitrous oxide maturation protein NosY
CCZ27_00170	ENOG4105CIG	ABC transporter
CCZ27_00175	ENOG4105DH4	Periplasmic copper-binding protein
CCZ27_00185	ENOG4105HEE	Binding Domain protein
CCZ27_00195	ENOG4105TX3	Histidine kinase
CCZ27_00245	ENOG4105C3G	gtp-binding protein
CCZ27_00255	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CCZ27_00260	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
CCZ27_00265	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CCZ27_00275	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CCZ27_00280	ENOG41081V9	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
CCZ27_00290	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
CCZ27_00295	ENOG410890F	Dynamin family
CCZ27_00300	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
CCZ27_00305	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CCZ27_00310	ENOG4106H78	methyltransferase
CCZ27_00315	ENOG4105C1V	Peptidase, M16
CCZ27_00330	ENOG4105CAK	Cell division ATP-binding protein ftsE
CCZ27_00335	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
CCZ27_00340	ENOG4105D3R	alkyl hydroperoxide reductase
CCZ27_00345	ENOG4108JU3	Alkyl hydroperoxide reductase
CCZ27_00350	ENOG4105BZU	Histidine kinase
CCZ27_00355	ENOG4105BZ1	(ABC) transporter
CCZ27_00375	ENOG4108YF6	methylamine dehydrogenase accessory protein MauD
CCZ27_00390	ENOG4105D25	secreted protein
CCZ27_00400	ENOG4107R13	MMPL domain protein
CCZ27_00415	ENOG4105C26	Dehydrogenase
CCZ27_00450	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
CCZ27_00455	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CCZ27_00475	ENOG4105DJB	Major Facilitator Superfamily
CCZ27_00490	ENOG4105ERH	Fumarylacetoacetate hydrolase
CCZ27_00495	ENOG4108VKG	metal-dependent hydrolase
CCZ27_00505	ENOG4105EA8	2-Nitropropane dioxygenase
CCZ27_00520	ENOG4105FVZ	flavin reductase domain protein, FMN-binding
CCZ27_00525	ENOG4105EFA	4-hydroxyphenylacetate
CCZ27_00540	ENOG4105D25	secreted protein
CCZ27_00555	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CCZ27_00565	ENOG4105CV8	reductase
CCZ27_00570	ENOG4105BZU	Histidine kinase
CCZ27_00575	ENOG4107Z6W	Protein CrcB homolog
CCZ27_00580	ENOG4105KJJ	Uncharacterized ACR, COG1993
CCZ27_00605	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CCZ27_00610	ENOG4105C9A	Phoh family
CCZ27_00615	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CCZ27_00620	ENOG4108JU5	Magnesium and cobalt efflux protein
CCZ27_00625	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
CCZ27_00645	ENOG4105C3K	feS assembly ATPase SufC
CCZ27_00650	ENOG4105JRK	feS assembly protein SufD
CCZ27_00655	ENOG4105C9B	Cysteine desulfurase
CCZ27_00660	ENOG4108UNV	SUF system FeS assembly protein, NifU family
CCZ27_00670	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
CCZ27_00680	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
CCZ27_00685	ENOG4105E9Q	Acyl-transferase
CCZ27_00700	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
CCZ27_00710	ENOG4105C2X	Arabinose 5-phosphate isomerase
CCZ27_00755	ENOG4107QHF	type ii secretion system protein e
CCZ27_00760	ENOG4105GVR	general secretion pathway protein D
CCZ27_00765	ENOG4105DHJ	ABC, transporter
CCZ27_00770	ENOG4105CY3	ABC transporter, permease
CCZ27_00775	ENOG4107PE3	Mammalian cell entry related domain protein
CCZ27_00795	ENOG4105DA5	(ABC) transporter
CCZ27_00800	ENOG4105E3A	(ABC) transporter
CCZ27_00810	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CCZ27_00820	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CCZ27_00825	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CCZ27_00830	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CCZ27_00835	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CCZ27_00840	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CCZ27_00845	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
CCZ27_00850	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CCZ27_00855	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CCZ27_00860	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
CCZ27_00865	ENOG4105K59	histidine triad (HIT) protein
CCZ27_00870	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
CCZ27_00875	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
CCZ27_00885	ENOG4105C0H	protease
CCZ27_00890	ENOG4107QNR	UPF0135 protein
CCZ27_00905	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
CCZ27_00910	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
CCZ27_00920	ENOG4107RF4	Phosphodiesterase
CCZ27_00925	ENOG4107QHF	type ii secretion system protein e
CCZ27_00930	ENOG4105DJV	ribulose-phosphate 3-epimerase
CCZ27_00935	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CCZ27_00960	ENOG4105DFP	Integrase
CCZ27_01040	ENOG4105W5Q	DNA repair protein (RadC
CCZ27_01160	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
CCZ27_01195	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
CCZ27_01220	ENOG4105CEY	Amp-dependent synthetase and ligase
CCZ27_01240	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
CCZ27_01245	ENOG4105CGU	Enoyl-CoA hydratase
CCZ27_01250	ENOG4105BZJ	Electron transfer flavoprotein
CCZ27_01255	ENOG4105C10	Electron transfer flavoprotein
CCZ27_01260	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CCZ27_01265	ENOG4105W8H	transhydrogenase (subunit alpha
CCZ27_01270	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CCZ27_01285	ENOG4106NZI	LysR family Transcriptional regulator
CCZ27_01300	ENOG4105DDQ	anthranilate synthase
CCZ27_01305	ENOG4107QYG	anthranilate phosphoribosyltransferase
CCZ27_01310	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CCZ27_01320	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CCZ27_01325	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CCZ27_01335	ENOG4108IV0	ABC, transporter
CCZ27_01340	ENOG4105C0Z	ABC transporter
CCZ27_01345	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
CCZ27_01350	ENOG4105C32	Amino acid ABC transporter (Permease)
CCZ27_01420	ENOG4105C1G	acyl-Coa dehydrogenase
CCZ27_01425	ENOG4105CSU	acyl-Coa dehydrogenase
CCZ27_01430	ENOG41061H0	Monooxygenase
CCZ27_01440	ENOG4105C26	Dehydrogenase
CCZ27_01445	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CCZ27_01465	ENOG4107Z67	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
CCZ27_01470	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
CCZ27_01475	ENOG4105BZ9	Cytochrome C oxidase, subunit I
CCZ27_01480	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
CCZ27_01490	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
CCZ27_01515	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
CCZ27_01525	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CCZ27_01530	ENOG4108Z9W	Outer membrane porin
CCZ27_01535	ENOG4105E2X	shikimate dehydrogenase
CCZ27_01545	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
CCZ27_01550	ENOG4105CHM	Aminotransferase
CCZ27_01555	ENOG4105MYN	Zinc uptake regulation protein
CCZ27_01570	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CCZ27_01590	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
CCZ27_01595	ENOG4105C6K	Malic enzyme
CCZ27_01605	ENOG41061WM	D-Alanyl-D-Alanine
CCZ27_01615	ENOG4105D65	subunit l
CCZ27_01620	ENOG4108ZE9	Monovalent cation H antiporter subunit C
CCZ27_01625	ENOG4107R4Z	monovalent cation h antiporter subunit d
CCZ27_01645	ENOG4105FE9	pseudouridine synthase
CCZ27_01665	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CCZ27_01670	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CCZ27_01675	ENOG4105EFX	secretion protein, HlyD family
CCZ27_01680	ENOG4105CX6	glutaminyL-tRNA synthetase
CCZ27_01685	ENOG4108ZG0	Ompa motb domain protein
CCZ27_01690	ENOG4105C0D	helicase
CCZ27_01695	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
CCZ27_01700	ENOG4107TYC	hydantoinase B oxoprolinase
CCZ27_01705	ENOG4105HKX	acetone carboxylase, gamma subunit
CCZ27_01710	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CCZ27_01730	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CCZ27_01735	ENOG4105DWF	phosphomethylpyrimidine kinase
CCZ27_01740	ENOG4108UHE	carbonic anhydrase
CCZ27_01745	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CCZ27_01755	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CCZ27_01765	ENOG4105DFG	type I secretion outer membrane protein
CCZ27_01770	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
CCZ27_01810	ENOG4105DA5	(ABC) transporter
CCZ27_01830	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
CCZ27_01840	ENOG4108Z20	Acyl-transferase
CCZ27_01850	ENOG4105K59	histidine triad (HIT) protein
CCZ27_01870	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CCZ27_01875	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CCZ27_01880	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
CCZ27_01885	ENOG4107ZT5	Thiol disulfide interchange protein
CCZ27_01895	ENOG4105DFU	Cell wall formation (By similarity)
CCZ27_01900	ENOG4105W4M	Transport-associated protein
CCZ27_01905	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
CCZ27_01910	ENOG41082RQ	UPF0102 protein
CCZ27_01915	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
CCZ27_01920	ENOG4105EKE	dihydroorotase
CCZ27_01935	ENOG4108V6E	Cell division protein mraZ
CCZ27_01940	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CCZ27_01945	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CCZ27_01950	ENOG4105CJN	penicillin-binding protein
CCZ27_01955	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CCZ27_01960	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
CCZ27_01965	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CCZ27_01970	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CCZ27_01975	ENOG4105CNI	cell division protein FtsW
CCZ27_01980	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CCZ27_01985	ENOG4105DFU	Cell wall formation (By similarity)
CCZ27_01990	ENOG4105CPF	Cell wall formation (By similarity)
CCZ27_01995	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
CCZ27_02000	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CCZ27_02005	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CCZ27_02010	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CCZ27_02025	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CCZ27_02030	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CCZ27_02065	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
CCZ27_02070	ENOG4105NWN	ApaG protein
CCZ27_02075	ENOG4107QTF	adenylosuccinate lyase
CCZ27_02085	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CCZ27_02090	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CCZ27_02095	ENOG4105VIE	preprotein translocase, subunit YajC
CCZ27_02100	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CCZ27_02105	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CCZ27_02115	ENOG41063Z6	transcriptional regulator, lysR family
CCZ27_02125	ENOG4108MN8	Membrane
CCZ27_02130	ENOG4105KJM	monovalent cation h antiporter subunit g
CCZ27_02135	ENOG4105W4C	monovalent cation H antiporter subunit F
CCZ27_02140	ENOG4105SC1	monovalent cation H antiporter subunit E
CCZ27_02145	ENOG4107R4Z	monovalent cation h antiporter subunit d
CCZ27_02150	ENOG4108ZE9	Monovalent cation H antiporter subunit C
CCZ27_02155	ENOG4105D65	subunit l
CCZ27_02165	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
CCZ27_02170	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CCZ27_02175	ENOG4108ZXC	Two component transcriptional regulator, luxr family
CCZ27_02180	ENOG4105BZU	Histidine kinase
CCZ27_02185	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CCZ27_02190	ENOG4108RA0	tripartite ATP-independent periplasmic transporter, DctQ component
CCZ27_02195	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CCZ27_02200	ENOG4105DQR	SNARE associated Golgi
CCZ27_02205	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
CCZ27_02210	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CCZ27_02220	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
CCZ27_02225	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CCZ27_02230	ENOG4105CUT	histidyl-tRNA synthetase
CCZ27_02240	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CCZ27_02245	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CCZ27_02250	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
CCZ27_02255	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CCZ27_02260	ENOG4107QJR	hflk protein
CCZ27_02265	ENOG4105EPW	hflc protein
CCZ27_02275	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
CCZ27_02280	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CCZ27_02295	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CCZ27_02300	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CCZ27_02310	ENOG4105D7T	ABC transporter
CCZ27_02315	ENOG4108IFG	nitrite reductase, (NAD(P)H)
CCZ27_02340	ENOG4108DBC	nitroreductase
CCZ27_02355	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CCZ27_02360	ENOG4105CH6	catalase
CCZ27_02365	ENOG4107QMP	dna polymerase iii subunits gamma and tau
CCZ27_02370	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CCZ27_02375	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CCZ27_02380	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CCZ27_02385	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CCZ27_02390	ENOG4105EIX	cytochrome c1
CCZ27_02395	ENOG4107MKT	Stringent starvation protein a
CCZ27_02400	ENOG4105KB2	stringent starvation protein b
CCZ27_02405	ENOG4105Y3Q	hemerythrin-like, metal-binding protein
CCZ27_02410	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CCZ27_02415	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CCZ27_02435	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
CCZ27_02440	ENOG4105CV8	reductase
CCZ27_02450	ENOG4105DAN	ATP-dependent protease
CCZ27_02460	ENOG41080ZE	Adenylate cyclase
CCZ27_02470	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CCZ27_02475	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CCZ27_02480	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CCZ27_02485	ENOG4105DHQ	Histidine kinase
CCZ27_02490	ENOG41062QD	Membrane
CCZ27_02495	ENOG4107QN1	sodium solute
CCZ27_02530	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CCZ27_02695	ENOG41067CV	Integrase
CCZ27_02700	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CCZ27_02705	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CCZ27_02710	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CCZ27_02740	ENOG4105D9P	serine threonine protein kinase
CCZ27_02745	ENOG4105CH7	arginosuccinase
CCZ27_02750	ENOG4108HRK	Histidine kinase
CCZ27_02755	ENOG4108NEV	two component transcriptional regulator, LytTR family
CCZ27_02760	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
CCZ27_02765	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CCZ27_02770	ENOG41076E6	Uroporphyrinogen-III Synthase
CCZ27_02775	ENOG4105ECF	c-methyltransferase
CCZ27_02785	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
CCZ27_02790	ENOG4105C12	Phosphoribosylglycinamide synthetase
CCZ27_02795	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CCZ27_02800	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
CCZ27_02805	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CCZ27_02815	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CCZ27_02820	ENOG4108UMI	ABC transporter, permease
CCZ27_02825	ENOG4105D01	(LipO)protein
CCZ27_02830	ENOG4105D0A	hydroxylase
CCZ27_02835	ENOG4107RAQ	aminopeptidase
CCZ27_02840	ENOG4108S0S	Nucleotidyl transferase
CCZ27_02845	ENOG4105EHM	Aminoglycoside phosphotransferase
CCZ27_02850	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
CCZ27_02860	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
CCZ27_02865	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CCZ27_02870	ENOG4105VN1	Heat shock protein
CCZ27_02885	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CCZ27_02890	ENOG4105C9M	aspartyl-trna synthetase
CCZ27_02905	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
CCZ27_02935	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CCZ27_02955	ENOG4108UYE	Lactoylglutathione lyase
CCZ27_02980	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CCZ27_02990	ENOG4105VCC	30S ribosomal protein S21
CCZ27_02995	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CCZ27_03000	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
CCZ27_03015	ENOG4108Z66	YbaK ebsC protein
CCZ27_03020	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CCZ27_03030	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CCZ27_03035	ENOG4105DJF	DNA polymerase III, delta' subunit
CCZ27_03045	ENOG4105C8T	Leucyl-tRNA synthetase
CCZ27_03055	ENOG4105C4R	Atp-dependent dna helicase
CCZ27_03060	ENOG4107QJE	Chromosome Partitioning Protein
CCZ27_03065	ENOG4105C6K	Malic enzyme
CCZ27_03070	ENOG4105HDD	phospholipase
CCZ27_03075	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
CCZ27_03080	ENOG4105C0B	DNA polymerase III (alpha subunit)
CCZ27_03085	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
CCZ27_03090	ENOG4105CHH	sulfate transporter
CCZ27_03095	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CCZ27_03115	ENOG4105DHP	deoxycytidine triphosphate deaminase
CCZ27_03120	ENOG4105CXN	decarboxylase
CCZ27_03130	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
CCZ27_03160	ENOG4108Z7G	MaoC domain protein dehydratase
CCZ27_03175	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CCZ27_03190	ENOG4105E4C	Lytic transglycosylase catalytic
CCZ27_03245	ENOG4105MVF	Transcriptional regulator
CCZ27_03275	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
CCZ27_03285	ENOG4105C5H	ABC transporter
CCZ27_03295	ENOG4108V0P	LemA family
CCZ27_03305	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
CCZ27_03315	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CCZ27_03330	ENOG4105D60	lipoprotein releasing system transmembrane protein
CCZ27_03335	ENOG4105CUZ	uba thif-type nad fad binding protein
CCZ27_03365	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CCZ27_03370	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CCZ27_03375	ENOG4105K46	50S ribosomal protein l27
CCZ27_03380	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CCZ27_03385	ENOG4105CQB	FAD linked oxidase domain protein
CCZ27_03395	ENOG4105EU8	FAD linked oxidase domain protein
CCZ27_03400	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
CCZ27_03405	ENOG4108ZF3	Phosphatase
CCZ27_03410	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CCZ27_03415	ENOG4105W8H	transhydrogenase (subunit alpha
CCZ27_03420	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CCZ27_03440	ENOG4105C1J	atp-dependent rna helicase
CCZ27_03445	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
CCZ27_03450	ENOG4105CPC	Aldo Keto reductase
CCZ27_03460	ENOG4105BZ7	extracellular solute-binding protein family 1
CCZ27_03465	ENOG4105EAH	synthase
CCZ27_03475	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CCZ27_03490	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CCZ27_03495	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CCZ27_03510	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
CCZ27_03525	ENOG4108Z4U	Ferredoxin
CCZ27_03540	ENOG4105CHB	tonB-dependent Receptor
CCZ27_03550	ENOG4105SG9	biopolymer transport protein, ExbD
CCZ27_03565	ENOG4105CPU	Monooxygenase
CCZ27_03580	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
CCZ27_03585	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
CCZ27_03590	ENOG4108JQ5	ABC transporter
CCZ27_03595	ENOG4105E43	Extracellular solute-binding protein, family 5
CCZ27_03600	ENOG4105BZ1	(ABC) transporter
CCZ27_03610	ENOG4105BZS	acriflavin resistance protein
CCZ27_03620	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CCZ27_03635	ENOG4105BZ1	(ABC) transporter
CCZ27_03640	ENOG4105BZ1	(ABC) transporter
CCZ27_03650	ENOG4107SM7	Transcriptional regulator
CCZ27_03655	ENOG4108UZX	fmn reductase
CCZ27_03665	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
CCZ27_03670	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
CCZ27_03690	ENOG4105BZ1	(ABC) transporter
CCZ27_03695	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
CCZ27_03700	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
CCZ27_03715	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CCZ27_03720	ENOG4105ERG	peptidase m48, ste24p
CCZ27_03725	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
CCZ27_03745	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CCZ27_03750	ENOG4108M8S	permease YjgP YjgQ family protein
CCZ27_03760	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CCZ27_03765	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CCZ27_03770	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CCZ27_03775	ENOG4105K5M	30s ribosomal protein S16
CCZ27_03785	ENOG4107S2Z	UPF0761 membrane protein
CCZ27_03790	ENOG4105CS1	NAD(P)H quinone oxidoreductase
CCZ27_03800	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CCZ27_03805	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
CCZ27_03810	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CCZ27_03815	ENOG4108ZP8	Acetolactate synthase small subunit
CCZ27_03820	ENOG4105C7K	acetolactate synthase
CCZ27_03840	ENOG4105CD8	aminopeptidase N
CCZ27_03860	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CCZ27_03865	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
CCZ27_03870	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CCZ27_03885	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CCZ27_03890	ENOG4105DJ0	Poly(A) Polymerase
CCZ27_03895	ENOG4108RXW	HAD-superfamily subfamily IB hydrolase
CCZ27_03900	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CCZ27_03905	ENOG4105C02	permease
CCZ27_03910	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CCZ27_03945	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
CCZ27_03955	ENOG410624X	efflux transporter, rnd family, mfp subunit
CCZ27_03960	ENOG4105BZS	acriflavin resistance protein
CCZ27_03975	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CCZ27_03985	ENOG4105CSU	acyl-Coa dehydrogenase
CCZ27_03995	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CCZ27_04005	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CCZ27_04020	ENOG4105N82	Endonuclease
CCZ27_04025	ENOG4105EGS	Mechanosensitive ion channel
CCZ27_04050	ENOG4105CFH	Aspartokinase
CCZ27_04060	ENOG4107RB3	L-asparaginase
CCZ27_04075	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CCZ27_04100	ENOG4105C34	Pseudouridine synthase
CCZ27_04105	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
CCZ27_04115	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
CCZ27_04120	ENOG4105CHR	reductase
CCZ27_04135	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
CCZ27_04140	ENOG4105D78	K07001 NTE family protein
CCZ27_04145	ENOG4105CQB	FAD linked oxidase domain protein
CCZ27_04195	ENOG4105WQT	MbtH domain protein
CCZ27_04210	ENOG4108VTW	Thioesterase
CCZ27_04240	ENOG4105CEY	Amp-dependent synthetase and ligase
CCZ27_04290	ENOG4105CTK	cobaltochelatase, cobn subunit
CCZ27_04295	ENOG4107QRP	cobalamin biosynthesis protein CobW
CCZ27_04305	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
CCZ27_04310	ENOG4105EHG	Permease protein
CCZ27_04320	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
CCZ27_04325	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CCZ27_04330	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CCZ27_04335	ENOG4105K63	Thioredoxin
CCZ27_04340	ENOG4108Z4U	Ferredoxin
CCZ27_04350	ENOG4105CEY	Amp-dependent synthetase and ligase
CCZ27_04355	ENOG4105C7K	acetolactate synthase
CCZ27_04360	ENOG4105M71	acetolactate synthase 1 regulatory subunit
CCZ27_04365	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CCZ27_04370	ENOG4105D8G	Major Facilitator superfamily
CCZ27_04375	ENOG4108K0D	peptidase, M48
CCZ27_04380	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CCZ27_04390	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CCZ27_04395	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CCZ27_04400	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CCZ27_04410	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
CCZ27_04415	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CCZ27_04420	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
CCZ27_04425	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CCZ27_04430	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CCZ27_04435	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
CCZ27_04440	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CCZ27_04455	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
CCZ27_04460	ENOG4105C28	cystathionine
CCZ27_04475	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
CCZ27_04480	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CCZ27_04485	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CCZ27_04490	ENOG4105C8N	cysteinyl-tRNA synthetase
CCZ27_04495	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CCZ27_04500	ENOG4105CFG	Acts as a chaperone (By similarity)
CCZ27_04505	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CCZ27_04565	ENOG4108RYK	Nad-dependent epimerase dehydratase
CCZ27_04570	ENOG4108ZHJ	Organic hydroperoxide resistance protein
CCZ27_04580	ENOG4105KVH	Transcriptional regulator
CCZ27_04585	ENOG4108PVQ	transcriptional regulator
CCZ27_04600	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
CCZ27_04605	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
CCZ27_04620	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
CCZ27_04625	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CCZ27_04645	ENOG4105C26	Dehydrogenase
CCZ27_04655	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
CCZ27_04660	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CCZ27_04665	ENOG4105CAF	HipA N-terminal domain protein
CCZ27_04680	ENOG4105WH1	Two component transcriptional regulator luxr family
CCZ27_04690	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
CCZ27_04695	ENOG4105CKW	Inner membrane protein yedI
CCZ27_04705	ENOG4105DZP	Membrane-associated zinc metalloprotease
CCZ27_04710	ENOG4105BZU	Histidine kinase
CCZ27_04715	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CCZ27_04730	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CCZ27_04740	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CCZ27_04745	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CCZ27_04750	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CCZ27_04760	ENOG4105CFV	Tetratricopeptide repeat protein
CCZ27_04765	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CCZ27_04770	ENOG4105C6T	cysteine synthase
CCZ27_04795	ENOG4105Y3U	Transglycosylase-associated protein
CCZ27_04805	ENOG4105C22	threonyL-tRNA synthetase
CCZ27_04810	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CCZ27_04815	ENOG4105VJV	50s ribosomal protein L35
CCZ27_04820	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CCZ27_04825	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CCZ27_04830	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CCZ27_04835	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CCZ27_04840	ENOG4108XDN	Transcriptional regulator
CCZ27_04880	ENOG4108Z86	Glutamine amidotransferase
CCZ27_04885	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
CCZ27_04895	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
CCZ27_04900	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CCZ27_04905	ENOG4108K5P	(LipO)protein
CCZ27_04910	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CCZ27_04920	ENOG4105CVE	Lytic murein transglycosylase
CCZ27_04925	ENOG4105F8C	transglutaminase domain-containing protein
CCZ27_04935	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CCZ27_04945	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CCZ27_04950	ENOG4105GJM	(LipO)protein
CCZ27_04965	ENOG4105EZE	Cupin 4 family protein
CCZ27_04970	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CCZ27_04980	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CCZ27_04985	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
CCZ27_04990	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
CCZ27_05020	ENOG4108R99	pseudouridine synthase
CCZ27_05030	ENOG4105D00	flagellar biosynthetic protein flhB
CCZ27_05035	ENOG4105D7B	Flagellar biosynthesis protein flha
CCZ27_05040	ENOG4105FZW	flagellar biosynthesis regulator FlhF
CCZ27_05050	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CCZ27_05055	ENOG4105E14	MotA TolQ exbB proton channel
CCZ27_05060	ENOG4106VK6	Flagellar motor protein
CCZ27_05065	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CCZ27_05075	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
CCZ27_05080	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
CCZ27_05085	ENOG4105XMH	SpoVT AbrB domain protein
CCZ27_05090	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CCZ27_05110	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
CCZ27_05115	ENOG4108ZC9	flagellar basal-body rod protein flgc
CCZ27_05125	ENOG4105BZE	flagellar hook protein, FlgE
CCZ27_05130	ENOG4108KPB	Flagellar basal-body rod protein FlgF
CCZ27_05135	ENOG4105CGA	flagellar basal-body rod protein FlgG
CCZ27_05140	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CCZ27_05145	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CCZ27_05150	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
CCZ27_05160	ENOG4105DTJ	flagellar hook-associated protein
CCZ27_05170	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
CCZ27_05175	ENOG4105VS8	Flagellar biosynthetic protein fliq
CCZ27_05180	ENOG4105CN7	Flagellar biosynthetic protein FliP
CCZ27_05185	ENOG4105VTB	flagellar biosynthesis protein fliO
CCZ27_05190	ENOG4105DD5	Flagellar motor switch protein
CCZ27_05195	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CCZ27_05215	ENOG4108JIR	Flagellum-specific ATP synthase
CCZ27_05225	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CCZ27_05230	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
CCZ27_05235	ENOG4105BZU	Histidine kinase
CCZ27_05245	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
CCZ27_05255	ENOG4108T7K	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity)
CCZ27_05260	ENOG4108T7K	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity)
CCZ27_05265	ENOG4105D00	flagellar biosynthetic protein flhB
CCZ27_05280	ENOG4105MQ3	flagellar protein FliS
CCZ27_05285	ENOG4105DTS	flagellar hook-associated
CCZ27_05295	ENOG4105I03	Flagellin
CCZ27_05310	ENOG4105D5D	udp-galactopyranose mutase
CCZ27_05330	ENOG4108JQ7	(ABC) transporter
CCZ27_05335	ENOG4105C3U	ABC transporter
CCZ27_05345	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CCZ27_05370	ENOG4105DEF	Extracellular solute-binding protein, family 5
CCZ27_05375	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
CCZ27_05395	ENOG4105C6T	cysteine synthase
CCZ27_05400	ENOG4105D7W	serine acetyltransferase
CCZ27_05410	ENOG4105ESN	nucleotide-binding protein
CCZ27_05415	ENOG4105C9B	Cysteine desulfurase
CCZ27_05440	ENOG4108JU7	Transcriptional regulator
CCZ27_05445	ENOG4107T8P	acyl-Coa dehydrogenase
CCZ27_05455	ENOG4105C0Z	ABC transporter
CCZ27_05490	ENOG4107T8P	acyl-Coa dehydrogenase
CCZ27_05500	ENOG4108IV0	ABC, transporter
CCZ27_05520	ENOG4105NX3	Membrane
CCZ27_05530	ENOG4105GVF	(ABC) transporter
CCZ27_05535	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
CCZ27_05550	ENOG4108UZX	fmn reductase
CCZ27_05555	ENOG4105FBW	Monooxygenase
CCZ27_05560	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
CCZ27_05595	ENOG4105M6W	Crispr-associated protein, Csy3 family
CCZ27_05605	ENOG4107SV5	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
CCZ27_05610	ENOG4105EAD	ABC transporter
CCZ27_05615	ENOG4105EAD	ABC transporter
CCZ27_05620	ENOG4105EAB	amino acid AbC transporter
CCZ27_05625	ENOG4105CNA	YD repeat protein
CCZ27_05650	ENOG4107TV1	YD repeat protein
CCZ27_05660	ENOG4105CNA	YD repeat protein
CCZ27_05675	ENOG4105CNA	YD repeat protein
CCZ27_05680	ENOG4105CNA	YD repeat protein
CCZ27_05685	ENOG4105CNA	YD repeat protein
CCZ27_05695	ENOG4105CHP	RNA polymerase
CCZ27_05710	ENOG4105GRZ	Ycii-related protein
CCZ27_05725	ENOG4105EPM	Diguanylate phosphodiesterase
CCZ27_05740	ENOG4105CA9	Pyruvate kinase
CCZ27_05765	ENOG4105F1A	Pyruvate formate-lyase
CCZ27_05770	ENOG4105TMB	Formate nitrite transporter
CCZ27_05775	ENOG4108HRK	Histidine kinase
CCZ27_05780	ENOG4108NEV	two component transcriptional regulator, LytTR family
CCZ27_05790	ENOG4107QPK	)-transporter
CCZ27_05800	ENOG4105CUC	YeeE YedE family protein
CCZ27_05805	ENOG4105KHC	sulfurtransferase
CCZ27_05815	ENOG4105E2Y	ABC, transporter
CCZ27_05820	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
CCZ27_05825	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
CCZ27_05830	ENOG4105GVF	(ABC) transporter
CCZ27_05835	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
CCZ27_05840	ENOG4107Z6A	sulfate abc transporter permease
CCZ27_05850	ENOG4108IJ6	ABC transporter
CCZ27_05855	ENOG4107R11	Transcriptional regulator
CCZ27_05885	ENOG4105WH1	Two component transcriptional regulator luxr family
CCZ27_05895	ENOG4105DZG	Dehydrogenase
CCZ27_05915	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CCZ27_05920	ENOG4105CS6	Rhs element vgr protein
CCZ27_05925	ENOG4105CNA	YD repeat protein
CCZ27_05950	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
CCZ27_05960	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CCZ27_05970	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CCZ27_05975	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
CCZ27_05980	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CCZ27_05985	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CCZ27_05995	ENOG4105K4H	Nlp p60 protein
CCZ27_06010	ENOG4108Z0R	Transferase
CCZ27_06015	ENOG4105D6S	protein involved in catabolism of external DNA
CCZ27_06025	ENOG4105CJ3	phosphate transporter
CCZ27_06035	ENOG4105EUJ	GTP cyclohydrolase i
CCZ27_06045	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
CCZ27_06060	ENOG4108VWS	Yaeq family
CCZ27_06075	ENOG4105C1J	atp-dependent rna helicase
CCZ27_06080	ENOG4105VEQ	Cold shock protein
CCZ27_06085	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
CCZ27_06105	ENOG4105DB7	PHP domain protein
CCZ27_06110	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
CCZ27_06115	ENOG4108Z4T	Peptidase M50
CCZ27_06120	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
CCZ27_06125	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
CCZ27_06130	ENOG4105FE9	pseudouridine synthase
CCZ27_06135	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
CCZ27_06140	ENOG4105CHV	Transcription elongation factor NusA
CCZ27_06145	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CCZ27_06150	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CCZ27_06155	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CCZ27_06160	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CCZ27_06165	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CCZ27_06170	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CCZ27_06190	ENOG4105FQT	
CCZ27_06210	ENOG4105CBX	hi0933 family
CCZ27_06220	ENOG4105IH7	synthase
CCZ27_06235	ENOG4105C0B	DNA polymerase III (alpha subunit)
CCZ27_06240	ENOG4105D60	lipoprotein releasing system transmembrane protein
CCZ27_06245	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CCZ27_06255	ENOG4108EC8	DNA internalization-related competence protein ComEC
CCZ27_06270	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CCZ27_06275	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
CCZ27_06280	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
CCZ27_06290	ENOG4105VFB	Binds the 23S rRNA (By similarity)
CCZ27_06295	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
CCZ27_06300	ENOG4108MIC	Mg-protoporphyrin IX methyl transferase
CCZ27_06305	ENOG4106RHG	Yeca family
CCZ27_06325	ENOG4105WQ3	Rna-binding protein
CCZ27_06330	ENOG4108K3A	Glutathione S-transferase
CCZ27_06345	ENOG4105K5B	UPF0225 protein
CCZ27_06350	ENOG4107QIJ	Aconitate hydratase 2
CCZ27_06395	ENOG4105CY0	Metallo-Beta-Lactamase
CCZ27_06400	ENOG4105DEN	Luciferase family
CCZ27_06410	ENOG4105D94	Major Facilitator Superfamily
CCZ27_06420	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CCZ27_06425	ENOG4105FDP	GntR family transcriptional regulator
CCZ27_06445	ENOG4105E33	succinate dehydrogenase
CCZ27_06450	ENOG4105Y75	tpr repeat protein
CCZ27_06455	ENOG4105BZN	citrate synthase
CCZ27_06460	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
CCZ27_06465	ENOG4105C7S	Dehydrogenase
CCZ27_06470	ENOG4107QN2	dihydrolipoyl dehydrogenase
CCZ27_06475	ENOG4105D6Z	AFG1 family ATPase
CCZ27_06480	ENOG4105DVT	helicase
CCZ27_06485	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
CCZ27_06490	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CCZ27_06495	ENOG4105M00	molybdopterin converting factor, subunit 1
CCZ27_06500	ENOG4108ZAF	Molybdopterin
CCZ27_06520	ENOG4108V0P	LemA family
CCZ27_06530	ENOG4105C5H	ABC transporter
CCZ27_06535	ENOG4105DP0	ferredoxin-NADP reductase
CCZ27_06540	ENOG4105DUM	transcriptional regulator, lysR family
CCZ27_06545	ENOG4105CJR	Integral membrane protein (MviN
CCZ27_06550	ENOG4108SF5	RNA Polymerase
CCZ27_06555	ENOG4108S3W	Anti-feci sigma factor, fecr
CCZ27_06585	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CCZ27_06600	ENOG4108SF5	RNA Polymerase
CCZ27_06635	ENOG4108IJ0	Aspartate ammonia-lyase
CCZ27_06640	ENOG4105CK2	sodium dicarboxylate symporter
CCZ27_06655	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CCZ27_06695	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CCZ27_06705	ENOG4105CUW	cytochrome C-TYPE protein
CCZ27_06720	ENOG4105Y7H	Cytochrome
CCZ27_06730	ENOG4108UMR	transcriptional regulator AsnC family
CCZ27_06740	ENOG4108UMR	transcriptional regulator AsnC family
CCZ27_06775	ENOG4105CUJ	penicillin amidase
CCZ27_06810	ENOG4105FAE	von Willebrand factor, type A
CCZ27_06825	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
CCZ27_06845	ENOG4105DSQ	Nitric oxide reductase
CCZ27_06850	ENOG4108VKQ	nitriC oxide reductase
CCZ27_06860	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
CCZ27_06865	ENOG4105CKK	Glycosyl transferase, family 2
CCZ27_06890	ENOG4108W2P	Methyl-accepting chemotaxis
CCZ27_06895	ENOG4107QUY	Guanine deaminase
CCZ27_06905	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CCZ27_06910	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
CCZ27_06915	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
CCZ27_06920	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CCZ27_06925	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
CCZ27_06945	ENOG4108YS0	lipoprotein YafL
CCZ27_06960	ENOG4108IAB	Phoh family
CCZ27_06965	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CCZ27_06975	ENOG4105CHM	Aminotransferase
CCZ27_06980	ENOG4105D6E	homoserine dehydrogenase
CCZ27_06990	ENOG4108RPX	mosc domain containing protein
CCZ27_07005	ENOG4105WKW	Pfam:DUF1458
CCZ27_07010	ENOG4105DAA	L-lactate
CCZ27_07025	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
CCZ27_07030	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
CCZ27_07035	ENOG41073TP	transcriptional regulator
CCZ27_07065	ENOG4105DGU	Histone deacetylase
CCZ27_07070	ENOG4105CH2	amidohydrolase
CCZ27_07075	ENOG4105CV6	ABC transporter, permease
CCZ27_07095	ENOG4105C0H	protease
CCZ27_07100	ENOG4105DHQ	Histidine kinase
CCZ27_07105	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CCZ27_07120	ENOG4105DCF	alanine dehydrogenase
CCZ27_07125	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CCZ27_07130	ENOG4105DAN	ATP-dependent protease
CCZ27_07145	ENOG4105CGF	Aromatic amino acid aminotransferase
CCZ27_07150	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CCZ27_07160	ENOG4105C03	ribonuclease
CCZ27_07170	ENOG4105EI2	Pseudouridine synthase
CCZ27_07175	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CCZ27_07180	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
CCZ27_07185	ENOG4108UHJ	MAF-like protein
CCZ27_07190	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
CCZ27_07195	ENOG4105VGS	50s ribosomal protein l32
CCZ27_07200	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
CCZ27_07205	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CCZ27_07210	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CCZ27_07215	ENOG4105CHR	reductase
CCZ27_07220	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CCZ27_07225	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CCZ27_07235	ENOG4108IYU	L-aspartate oxidase
CCZ27_07240	ENOG4105EMN	RNA polymerase sigma factor
CCZ27_07250	ENOG4105VQK	sigma E regulatory protein, MucB RseB
CCZ27_07260	ENOG4105C0H	protease
CCZ27_07270	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CCZ27_07275	ENOG4105C3F	Signal peptidase i
CCZ27_07285	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CCZ27_07290	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CCZ27_07295	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
CCZ27_07300	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
CCZ27_07305	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
CCZ27_07315	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
CCZ27_07320	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CCZ27_07350	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
CCZ27_07355	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CCZ27_07360	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
CCZ27_07365	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
CCZ27_07375	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CCZ27_07390	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
CCZ27_07410	ENOG4105CFF	transcriptional regulator
CCZ27_07415	ENOG4105BZN	citrate synthase
CCZ27_07420	ENOG4108I0Z	Aconitate hydratase
CCZ27_07425	ENOG4105C7F	AcnD-accessory protein PrpF
CCZ27_07435	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
CCZ27_07460	ENOG4105CFF	transcriptional regulator
CCZ27_07465	ENOG4105C26	Dehydrogenase
CCZ27_07470	ENOG4105C1G	acyl-Coa dehydrogenase
CCZ27_07475	ENOG4105E39	Enoyl-CoA hydratase
CCZ27_07480	ENOG4105CGU	Enoyl-CoA hydratase
CCZ27_07485	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
CCZ27_07490	ENOG4105WPN	DNA integration recombination invertion protein
CCZ27_07495	ENOG4105ECQ	AraC Family Transcriptional Regulator
CCZ27_07505	ENOG4105DZ2	Transcriptional regulator
CCZ27_07555	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
CCZ27_07560	ENOG4105EHG	Permease protein
CCZ27_07575	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CCZ27_07595	ENOG4105DHU	Bile acid
CCZ27_07600	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CCZ27_07610	ENOG4105GBT	ABC transporter
CCZ27_07615	ENOG4105E5Q	amino acid AbC transporter
CCZ27_07630	ENOG4107SQD	Transcriptional regulator, GntR family
CCZ27_07655	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
CCZ27_07660	ENOG4107QMS	site-determining protein
CCZ27_07665	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
CCZ27_07670	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
CCZ27_07675	ENOG4105KUZ	arsenate reductase
CCZ27_07680	ENOG4105BZM	domain protein
CCZ27_07700	ENOG4105CD5	CoA-binding domain protein
CCZ27_07715	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
CCZ27_07720	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
CCZ27_07725	ENOG4108UJV	acyl-CoA thioesterase i
CCZ27_07730	ENOG4108I0Y	(ABC) transporter
CCZ27_07735	ENOG4105EAC	phosphoserine phosphatase
CCZ27_07740	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CCZ27_07745	ENOG4108R3E	Dna-3-methyladenine glycosylase i
CCZ27_07750	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
CCZ27_07760	ENOG4105CFP	Peptidase U32
CCZ27_07780	ENOG41080IJ	Diacylglycerol kinase
CCZ27_07805	ENOG4107STF	Involved in phosphonate degradation (By similarity)
CCZ27_07810	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
CCZ27_07920	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CCZ27_07945	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CCZ27_07960	ENOG4105C2C	drug resistance transporter, Bcr CflA
CCZ27_07990	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CCZ27_08005	ENOG4105DFH	Transport of potassium into the cell (By similarity)
CCZ27_08010	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
CCZ27_08025	ENOG4108JJA	ABC, transporter
CCZ27_08040	ENOG4108Z6B	deaminase
CCZ27_08045	ENOG4108QQZ	ErfK YbiS YcfS YnhG family protein
CCZ27_08050	ENOG41082BV	acetyltransferase
CCZ27_08065	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
CCZ27_08070	ENOG4105HHA	aminodeoxychorismate lyase
CCZ27_08075	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CCZ27_08080	ENOG4107QRG	dna polymerase iii
CCZ27_08090	ENOG4105F8V	Hydrolase, tatD family
CCZ27_08100	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
CCZ27_08105	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CCZ27_08110	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
CCZ27_08115	ENOG4105ED1	spovr family
CCZ27_08120	ENOG4106AKX	UPF0229 protein
CCZ27_08125	ENOG4105CYN	Serine protein kinase
CCZ27_08130	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CCZ27_08135	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CCZ27_08140	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CCZ27_08145	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CCZ27_08150	ENOG4105K70	DNA-binding protein
CCZ27_08160	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CCZ27_08270	ENOG4108QMY	dioxygenase
CCZ27_08275	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CCZ27_08300	ENOG4108ZMQ	domain protein
CCZ27_08310	ENOG4107QI1	Mate efflux family protein
CCZ27_08325	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CCZ27_08340	ENOG4108YZY	peptidylprolyl cis-trans isomerase
CCZ27_08350	ENOG4105E9H	Lytic Murein transglycosylase
CCZ27_08355	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CCZ27_08360	ENOG4105D1A	Methyltransferase
CCZ27_08365	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CCZ27_08370	ENOG4108JDX	DNA polymerase iii, epsilon subunit
CCZ27_08380	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CCZ27_08385	ENOG4105ECY	inositol monophosphatase
CCZ27_08395	ENOG4105D7W	serine acetyltransferase
CCZ27_08405	ENOG4105C3J	Cysteine desulfurase
CCZ27_08410	ENOG4105C3J	Cysteine desulfurase
CCZ27_08415	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
CCZ27_08420	ENOG4108Z4V	iron-sulfur cluster assembly
CCZ27_08425	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
CCZ27_08430	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
CCZ27_08435	ENOG4108ZIT	Ferredoxin, 2FE-2S
CCZ27_08440	ENOG4105WVQ	Fe-S assembly protein IscX
CCZ27_08450	ENOG4107QQR	Sporulation
CCZ27_08460	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CCZ27_08465	ENOG4105CZX	twitching motility protein
CCZ27_08470	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
CCZ27_08480	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
CCZ27_08490	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CCZ27_08495	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CCZ27_08505	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
CCZ27_08515	ENOG4108TEB	UPF0114 protein
CCZ27_08520	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
CCZ27_08525	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CCZ27_08530	ENOG4105CE9	30S ribosomal protein S2
CCZ27_08535	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CCZ27_08540	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CCZ27_08545	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CCZ27_08550	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CCZ27_08555	ENOG4105KNE	Phosphatidate cytidylyltransferase
CCZ27_08560	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CCZ27_08565	ENOG4105DZP	Membrane-associated zinc metalloprotease
CCZ27_08570	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCZ27_08580	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CCZ27_08585	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CCZ27_08590	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CCZ27_08595	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CCZ27_08600	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CCZ27_08610	ENOG4105D1Q	UPF0246 protein
CCZ27_08620	ENOG4107S11	squalene-associated FAD-dependent desaturase
CCZ27_08635	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CCZ27_08640	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CCZ27_08650	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
CCZ27_08670	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CCZ27_08805	ENOG4105C10	Electron transfer flavoprotein
CCZ27_08810	ENOG4105BZJ	Electron transfer flavoprotein
CCZ27_08820	ENOG4105DND	Transcriptional regulator
CCZ27_08830	ENOG4105EUJ	GTP cyclohydrolase i
CCZ27_08840	ENOG4105E39	Enoyl-CoA hydratase
CCZ27_08845	ENOG4105D2B	acyl-CoA dehydrogenase
CCZ27_08850	ENOG4105CC9	acyl-Coa dehydrogenase
CCZ27_08860	ENOG4106A3M	Cytochrome p-450
CCZ27_08865	ENOG4105CHR	reductase
CCZ27_08885	ENOG4105CHR	reductase
CCZ27_08890	ENOG4108MXC	l-carnitine dehydratase bile acid-inducible protein F
CCZ27_08920	ENOG4105EWK	phytoene
CCZ27_08940	ENOG4105CYC	Transferase
CCZ27_08945	ENOG4105KT5	UmuD protein
CCZ27_08950	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
CCZ27_08980	ENOG4108ZQS	transposase
CCZ27_09050	ENOG4108UPT	UPF0178 protein
CCZ27_09200	ENOG4105YAJ	CopG Arc MetJ
CCZ27_09225	ENOG4105CHC	glucokinase (EC 2.7.1.2)
CCZ27_09230	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
CCZ27_09235	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
CCZ27_09240	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
CCZ27_09245	ENOG4105C08	Histidine kinase
CCZ27_09250	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
CCZ27_09255	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
CCZ27_09260	ENOG4105XMH	SpoVT AbrB domain protein
CCZ27_09305	ENOG4107QP8	phosphohexose isomerase
CCZ27_09315	ENOG4107QJN	gtp cyclohydrolase ii
CCZ27_09345	ENOG4108JJ6	Type I secretion system ATPase
CCZ27_09385	ENOG4105EMU	Dehydrogenase
CCZ27_09395	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
CCZ27_09435	ENOG4105IKI	host-nuclease inhibitor protein
CCZ27_09670	ENOG4107QM5	aconitate hydratase
CCZ27_09675	ENOG4108YS2	small subunit
CCZ27_09680	ENOG4108Q89	anthranilate 1,2-dioxygenase large subunit
CCZ27_09695	ENOG410814C	multidrug resistance protein
CCZ27_09700	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
CCZ27_09705	ENOG4108MK9	spermidine N(1)-acetyltransferase
CCZ27_09710	ENOG4108RW8	Universal stress protein F
CCZ27_09720	ENOG4105VT2	5-hydroxyisourate hydrolase
CCZ27_09740	ENOG4105DHG	Allantoate amidinohydrolase
CCZ27_09745	ENOG4108Z2U	ureidoglycolate hydrolase
CCZ27_09750	ENOG4105E3A	(ABC) transporter
CCZ27_09755	ENOG4105DA5	(ABC) transporter
CCZ27_09765	ENOG4108NSC	Pfam:DUF88
CCZ27_09775	ENOG4105BZU	Histidine kinase
CCZ27_09780	ENOG4108NIW	Leucine export protein LeuE
CCZ27_09785	ENOG4108Q5Y	Membrane
CCZ27_09795	ENOG4105CK2	sodium dicarboxylate symporter
CCZ27_09800	ENOG4105DHG	Allantoate amidinohydrolase
CCZ27_09805	ENOG4108Z2U	ureidoglycolate hydrolase
CCZ27_09810	ENOG4105IW1	AmiS UreI transporter
CCZ27_09815	ENOG4105C2W	permease
CCZ27_09830	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CCZ27_09835	ENOG4105DUM	transcriptional regulator, lysR family
CCZ27_09845	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
CCZ27_09850	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
CCZ27_09855	ENOG41072GX	Peptidase M22 Glycoprotease
CCZ27_09865	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CCZ27_09870	ENOG4105E0F	Histidine kinase
CCZ27_09875	ENOG4107QPB	Beta-lactamase domain protein
CCZ27_09885	ENOG4107835	probably involved in intracellular septation (By similarity)
CCZ27_09890	ENOG4105K9H	YciI-like protein
CCZ27_09900	ENOG4107TF3	peptidylprolyl cis-trans isomerase
CCZ27_09905	ENOG4105CSU	acyl-Coa dehydrogenase
CCZ27_09915	ENOG4105C10	Electron transfer flavoprotein
CCZ27_09920	ENOG4105BZJ	Electron transfer flavoprotein
CCZ27_09925	ENOG4108IG5	Transcriptional regulator
CCZ27_09930	ENOG4105EYA	deoxyribonuclease
CCZ27_09935	ENOG4105E39	Enoyl-CoA hydratase
CCZ27_09940	ENOG4105CEY	Amp-dependent synthetase and ligase
CCZ27_09955	ENOG4105DHJ	ABC, transporter
CCZ27_09965	ENOG4105C9X	ppx gppa phosphatase
CCZ27_09970	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
CCZ27_09975	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CCZ27_09995	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CCZ27_10000	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
CCZ27_10005	ENOG4107PU6	Membrane
CCZ27_10010	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
CCZ27_10015	ENOG4105NBF	ammecr1 domain protein
CCZ27_10030	ENOG4108JA2	transcriptioN-repair coupling factor
CCZ27_10035	ENOG4105D7N	magnesium and cobalt transport protein CorA
CCZ27_10050	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
CCZ27_10055	ENOG4105K8N	protein family UPF0079, ATPase
CCZ27_10060	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CCZ27_10065	ENOG4105DTN	riboflavin biosynthesis protein ribF
CCZ27_10070	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CCZ27_10075	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CCZ27_10080	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
CCZ27_10085	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CCZ27_10095	ENOG41082UU	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CCZ27_10100	ENOG4105CTB	Polyprenyl synthetase
CCZ27_10105	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CCZ27_10110	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
CCZ27_10170	ENOG4106T14	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CCZ27_10175	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CCZ27_10185	ENOG4105D1H	recombination factor protein RarA
CCZ27_10190	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
CCZ27_10195	ENOG4105CNU	cell division protein FtsK
CCZ27_10200	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
CCZ27_10205	ENOG4105C3M	thioredoxin reductase
CCZ27_10210	ENOG4108DG9	Smr protein MutS2
CCZ27_10215	ENOG4108YZA	Nitrogen regulatory protein pii
CCZ27_10220	ENOG4105C4K	Nad synthetase
CCZ27_10235	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CCZ27_10240	ENOG4105C8S	subunit m
CCZ27_10250	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CCZ27_10255	ENOG4105DF2	NADH dehydrogenase subunit j
CCZ27_10260	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CCZ27_10265	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
CCZ27_10270	ENOG4108IEH	NADH dehydrogenase subunit g
CCZ27_10270	ENOG4108IEH	NADH dehydrogenase subunit g
CCZ27_10280	ENOG4105GKE	subunit e
CCZ27_10285	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CCZ27_10290	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CCZ27_10295	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CCZ27_10300	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CCZ27_10310	ENOG4107EJC	Preprotein translocase subunit SecG
CCZ27_10315	ENOG4105CP7	Triose-phosphate isomerase
CCZ27_10320	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
CCZ27_10330	ENOG4105C4R	Atp-dependent dna helicase
CCZ27_10335	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CCZ27_10345	ENOG4105C8U	phosphate abc transporter
CCZ27_10360	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
CCZ27_10365	ENOG41080ET	plasmid maintenance system killer protein
CCZ27_10505	ENOG4105T95	Thiol disulfide interChange protein
CCZ27_10610	ENOG4107QRT	dEAD DEAH box helicase
CCZ27_10620	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
CCZ27_10690	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
CCZ27_10750	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
CCZ27_10755	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
CCZ27_10835	ENOG4105D25	secreted protein
CCZ27_10855	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
CCZ27_10875	ENOG4105W5Q	DNA repair protein (RadC
CCZ27_10915	ENOG4107QJE	Chromosome Partitioning Protein
CCZ27_10930	ENOG4105KT5	UmuD protein
CCZ27_10950	ENOG4105DFP	Integrase
CCZ27_10955	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CCZ27_10960	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CCZ27_10970	ENOG4105VDB	UPF0125 protein
CCZ27_10975	ENOG4108Z1B	Cyclase dehydrase
CCZ27_10980	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CCZ27_10985	ENOG4105CNG	UPF0061 protein
CCZ27_10990	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CCZ27_11005	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
CCZ27_11010	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
CCZ27_11015	ENOG4105BZU	Histidine kinase
CCZ27_11020	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CCZ27_11025	ENOG4107QN1	sodium solute
CCZ27_11030	ENOG4108IRC	dna polymerase iii
CCZ27_11035	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CCZ27_11040	ENOG4105BZU	Histidine kinase
CCZ27_11050	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CCZ27_11060	ENOG4105BZU	Histidine kinase
CCZ27_11070	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
CCZ27_11080	ENOG4105E0X	reductase
CCZ27_11085	ENOG4105CHU	acetyl-coa acetyltransferase
CCZ27_11135	ENOG4108VPT	UPF0234 protein
CCZ27_11140	ENOG4105NBK	UPF0345 protein
CCZ27_11150	ENOG4105CDH	Citrulline--aspartate ligase
CCZ27_11155	ENOG4105DBV	ornithine carbamoyltransferase
CCZ27_11160	ENOG4105C8Y	Acetylornithine aminotransferase
CCZ27_11170	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CCZ27_11175	ENOG4105E2Z	phosphate ABC transporter (Permease
CCZ27_11180	ENOG4105C8U	phosphate abc transporter
CCZ27_11185	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
CCZ27_11190	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CCZ27_11195	ENOG4105EEI	dihydropteroate synthase
CCZ27_11200	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CCZ27_11205	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
CCZ27_11210	ENOG4105HBR	Rna-binding protein
CCZ27_11220	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CCZ27_11225	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CCZ27_11230	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CCZ27_11235	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CCZ27_11240	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CCZ27_11245	ENOG41090R7	Ferric uptake
CCZ27_11250	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CCZ27_11255	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CCZ27_11260	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
CCZ27_11265	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CCZ27_11270	ENOG4105D9P	serine threonine protein kinase
CCZ27_11275	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CCZ27_11280	ENOG4105UYK	outer membrane protein a
CCZ27_11285	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CCZ27_11295	ENOG4105CVE	Lytic murein transglycosylase
CCZ27_11300	ENOG4105BZF	Glycosyl transferase (Group 1
CCZ27_11315	ENOG4105CFG	Acts as a chaperone (By similarity)
CCZ27_11345	ENOG4105CCT	upf0313 protein
CCZ27_11350	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
CCZ27_11355	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CCZ27_11365	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CCZ27_11370	ENOG4105CYN	Serine protein kinase
CCZ27_11375	ENOG4106AKX	UPF0229 protein
CCZ27_11380	ENOG4105ED1	spovr family
CCZ27_11430	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CCZ27_11440	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
CCZ27_11445	ENOG4105KWI	UPF0339 protein
CCZ27_11455	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
CCZ27_11475	ENOG4105FB9	CRISPR-associated protein
CCZ27_11485	ENOG4105C8Q	Methyl-accepting chemotaxis
CCZ27_11490	ENOG4105CRK	lysyL-tRNA synthetase
CCZ27_11505	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
CCZ27_11525	ENOG4105E4G	Type IV pilus
CCZ27_11550	ENOG4107QHF	type ii secretion system protein e
CCZ27_11555	ENOG4105D7Q	type ii secretion system
CCZ27_11560	ENOG4108VAU	general secretion pathway protein G
CCZ27_11565	ENOG4105E4C	Lytic transglycosylase catalytic
CCZ27_11585	ENOG4105SG9	biopolymer transport protein, ExbD
CCZ27_11595	ENOG4105E02	MotA TolQ exbB proton channel
CCZ27_11625	ENOG4105VJY	transcriptional regulator
CCZ27_11690	ENOG4105BZU	Histidine kinase
CCZ27_11695	ENOG4105DR5	peptidase
CCZ27_11720	ENOG4105FGF	GDP-mannose mannosyl hydrolase
CCZ27_11730	ENOG4105E2K	Glycosyl transferase (Group 1
CCZ27_11745	ENOG4108I69	Glycosyl transferases group 1
CCZ27_11750	ENOG4107T8Q	Glycosyl transferase (Group 1
CCZ27_11785	ENOG4105C30	Nad-dependent epimerase dehydratase
CCZ27_11790	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
CCZ27_11815	ENOG4105DAY	polysaccharide export protein
CCZ27_11830	ENOG4105D3Q	Sugar transferase
CCZ27_11840	ENOG4107QUT	magnesium and cobalt transport protein CorA
CCZ27_11845	ENOG4105CSR	polyphosphate kinase 2
CCZ27_11865	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
CCZ27_11870	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
CCZ27_11885	ENOG4105DHT	Metal Dependent Phosphohydrolase
CCZ27_11895	ENOG4105CC0	LysR family Transcriptional regulator
CCZ27_11900	ENOG4105C2I	pirin domain protein
CCZ27_11905	ENOG4105CHJ	isochorismatase hydrolase
CCZ27_11915	ENOG4105EFZ	amidohydrolase
CCZ27_11950	ENOG4107MBT	Plasmid stabilisation system protein
CCZ27_11970	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CCZ27_11975	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
CCZ27_11980	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
CCZ27_11985	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CCZ27_12000	ENOG4108ZXC	Two component transcriptional regulator, luxr family
CCZ27_12010	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
CCZ27_12015	ENOG4107QSN	dihydrolipoamide acetyltransferase
CCZ27_12020	ENOG4107QN2	dihydrolipoyl dehydrogenase
CCZ27_12050	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CCZ27_12055	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CCZ27_12070	ENOG4107QZ7	Cellulose synthase catalytic subunit
CCZ27_12075	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CCZ27_12080	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
CCZ27_12085	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CCZ27_12090	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
CCZ27_12095	ENOG4105W49	UPF0434 protein
CCZ27_12100	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
CCZ27_12105	ENOG4109015	Biopolymer transport protein exbD tolR
CCZ27_12115	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CCZ27_12120	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CCZ27_12150	ENOG4105E0Y	RtcB Protein
CCZ27_12210	ENOG4105ESI	atpase involved in dna repair
CCZ27_12230	ENOG4105CFG	Acts as a chaperone (By similarity)
CCZ27_12275	ENOG4108RAV	Conserved protein
CCZ27_12310	ENOG4105CHJ	isochorismatase hydrolase
CCZ27_12340	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CCZ27_12345	ENOG4105JQN	Transcriptional regulator
CCZ27_12350	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CCZ27_12355	ENOG4105BZU	Histidine kinase
CCZ27_12360	ENOG4105DR9	pseudouridine synthase
CCZ27_12365	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CCZ27_12370	ENOG4105CBS	Chea signal transduction histidine kinase
CCZ27_12375	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
CCZ27_12380	ENOG4108VYJ	response regulator receiver protein
CCZ27_12385	ENOG4107R88	Chemotaxis protein (CheV)
CCZ27_12390	ENOG4107R88	Chemotaxis protein (CheV)
CCZ27_12395	ENOG4105ER2	Ompa motb domain protein
CCZ27_12400	ENOG4107RD7	Flagellar Motor Protein, MotA
CCZ27_12405	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
CCZ27_12410	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
CCZ27_12415	ENOG4105BZU	Histidine kinase
CCZ27_12425	ENOG4105DGN	Electron transport complex
CCZ27_12430	ENOG4108R3D	Electron transport complex
CCZ27_12435	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
CCZ27_12445	ENOG4108UQQ	Electron transport complex
CCZ27_12455	ENOG4105CSM	endonuclease III
CCZ27_12465	ENOG4105E7A	Glutamine amidotransferase
CCZ27_12470	ENOG4105C6T	cysteine synthase
CCZ27_12475	ENOG4105C28	cystathionine
CCZ27_12480	ENOG4106RE7	Cytochrome
CCZ27_12485	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CCZ27_12500	ENOG4105PX9	Transcriptional regulator, MarR family
CCZ27_12510	ENOG4105EA8	2-Nitropropane dioxygenase
CCZ27_12545	ENOG4105BZU	Histidine kinase
CCZ27_12555	ENOG4108YYC	ycei family
CCZ27_12560	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CCZ27_12565	ENOG4108RRZ	Transcription elongation factor GreB
CCZ27_12590	ENOG4105PGM	cation diffusion facilitator family transporter
CCZ27_12630	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CCZ27_12650	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
CCZ27_12665	ENOG4105F0N	pyrophosphate phospho-hydrolase
CCZ27_12670	ENOG4105CA0	peroxidase
CCZ27_12675	ENOG4105PE1	Receptor
CCZ27_12680	ENOG4108S3W	Anti-feci sigma factor, fecr
CCZ27_12685	ENOG4108SF5	RNA Polymerase
CCZ27_12695	ENOG4105C59	p-type ATPase
CCZ27_12700	ENOG4105W1Y	Transcriptional regulator
CCZ27_12710	ENOG4105D4P	Coproporphyrinogen iii oxidase
CCZ27_12715	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
CCZ27_12720	ENOG4108YY7	Invasion gene expression up-regulator SirB
CCZ27_12735	ENOG4105DUM	transcriptional regulator, lysR family
CCZ27_12740	ENOG4105E2Y	ABC, transporter
CCZ27_12750	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
CCZ27_12755	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
CCZ27_12760	ENOG4108UZX	fmn reductase
CCZ27_12765	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
CCZ27_12770	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CCZ27_12775	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
CCZ27_12795	ENOG4105CPU	Monooxygenase
CCZ27_12825	ENOG4105SG9	biopolymer transport protein, ExbD
CCZ27_12835	ENOG4105MP9	class II Aldolase
CCZ27_12840	ENOG4108T2C	cysteine dioxygenase type I
CCZ27_12845	ENOG4105CY0	Metallo-Beta-Lactamase
CCZ27_12875	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
CCZ27_12890	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
CCZ27_12900	ENOG4105C59	p-type ATPase
CCZ27_12925	ENOG4105EJC	lysr family transcriptional regulator
CCZ27_12935	ENOG4107QP3	malate synthase g
CCZ27_12940	ENOG4105DXC	membrane
CCZ27_12955	ENOG41067MG	lrgb family
CCZ27_12995	ENOG4108HMX	isocitrate dehydrogenase (NADP)
CCZ27_13000	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
CCZ27_13015	ENOG410692J	cytochrome C, class I
CCZ27_13020	ENOG4107S7U	Sulfide dehydrogenase
CCZ27_13030	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
CCZ27_13035	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CCZ27_13040	ENOG4105W5Q	DNA repair protein (RadC
CCZ27_13045	ENOG4105KDC	50s ribosomal protein l28
CCZ27_13050	ENOG4105W0E	50S ribosomal protein L33
CCZ27_13055	ENOG4105VEQ	Cold shock protein
CCZ27_13060	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
CCZ27_13065	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CCZ27_13070	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
CCZ27_13075	ENOG4108I9X	Isocitrate lyase
CCZ27_13085	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CCZ27_13090	ENOG4105E0F	Histidine kinase
CCZ27_13095	ENOG4105ETT	transcriptional Regulator, LysR family
CCZ27_13110	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
CCZ27_13125	ENOG4105KHC	sulfurtransferase
CCZ27_13130	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CCZ27_13135	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CCZ27_13140	ENOG4105DR5	peptidase
CCZ27_13145	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
CCZ27_13150	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
CCZ27_13155	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
CCZ27_13180	ENOG4105FIE	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) (By similarity)
CCZ27_13185	ENOG4105DCC	Formylmethanofuran dehydrogenase subunit A
CCZ27_13240	ENOG4108P4C	Formaldehyde-activating enzyme
CCZ27_13245	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CCZ27_13250	ENOG41068T5	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT (By similarity)
CCZ27_13255	ENOG4108M6X	Dehydrogenase
CCZ27_13270	ENOG4105KZX	Pterin carbinolamine dehydratase
CCZ27_13285	ENOG4105DZG	Dehydrogenase
CCZ27_13330	ENOG4105BZU	Histidine kinase
CCZ27_13355	ENOG4105CJ1	ABC, transporter
CCZ27_13380	ENOG4105BZU	Histidine kinase
CCZ27_13385	ENOG4105WH1	Two component transcriptional regulator luxr family
CCZ27_13390	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
CCZ27_13395	ENOG4105WF7	pyrroloquinoline quinone biosynthesis protein d
CCZ27_13400	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
CCZ27_13405	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
CCZ27_13420	ENOG4108UJD	30S ribosomal protein S9
CCZ27_13425	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CCZ27_13430	ENOG4108UKZ	OsmC family
CCZ27_13435	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
CCZ27_13450	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
CCZ27_13465	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CCZ27_13470	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CCZ27_13475	ENOG4105E4C	Lytic transglycosylase catalytic
CCZ27_13485	ENOG4107WP9	Histidine kinase
CCZ27_13495	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CCZ27_13510	ENOG4105DHT	Metal Dependent Phosphohydrolase
CCZ27_13515	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
CCZ27_13530	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
CCZ27_13550	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CCZ27_13565	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CCZ27_13580	ENOG4105DNZ	Alpha Beta Hydrolase
CCZ27_13590	ENOG4105NAU	thioesterase Superfamily protein
CCZ27_13595	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CCZ27_13600	ENOG4108WBT	adenosyltransferase
CCZ27_13605	ENOG4108Z9W	Outer membrane porin
CCZ27_13615	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CCZ27_13620	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CCZ27_13640	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
CCZ27_13645	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
CCZ27_13650	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
CCZ27_13655	ENOG4105N42	UPF0307 protein
CCZ27_13660	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
CCZ27_13670	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CCZ27_13675	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CCZ27_13680	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CCZ27_13685	ENOG4105D06	uba thif-type nad fad binding protein
CCZ27_13695	ENOG4105CN1	protease
CCZ27_13705	ENOG41080HT	Transcriptional regulator, arsr family
CCZ27_13710	ENOG4107YZP	Rhodanese domain protein
CCZ27_13715	ENOG4105VW4	glutaredoxin 3
CCZ27_13720	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
CCZ27_13730	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CCZ27_13735	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
CCZ27_13740	ENOG4105MJ2	Competence protein
CCZ27_13745	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CCZ27_13760	ENOG4105D52	delta-aminolevulinic acid dehydratase
CCZ27_13775	ENOG4105ED9	Protein of unknown function (DUF455)
CCZ27_13780	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CCZ27_13785	ENOG4105E66	phosphoriboisomerase A
CCZ27_13790	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
CCZ27_13795	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
CCZ27_13800	ENOG4105BZU	Histidine kinase
CCZ27_13805	ENOG4108EKC	n-acetylglutamate synthase
CCZ27_13810	ENOG4105CSR	polyphosphate kinase 2
CCZ27_13815	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
CCZ27_13825	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
CCZ27_13835	ENOG4105CV1	Transketolase (EC 2.2.1.1)
CCZ27_13840	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CCZ27_13845	ENOG4105BZA	Phosphoglycerate kinase
CCZ27_13870	ENOG4105DUM	transcriptional regulator, lysR family
CCZ27_13880	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
CCZ27_13890	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CCZ27_13895	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
CCZ27_13915	ENOG4105CK2	sodium dicarboxylate symporter
CCZ27_13925	ENOG4105C8V	SAICAR synthetase
CCZ27_13940	ENOG4105DGW	oligopeptidase A
CCZ27_13955	ENOG4108VCT	Sulfite exporter TauE/SafE
CCZ27_13965	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
CCZ27_13975	ENOG4105CAS	nag kinase
CCZ27_13985	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CCZ27_13995	ENOG4105C11	sulfate adenylyltransferase), subunit 2
CCZ27_14000	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
CCZ27_14005	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CCZ27_14010	ENOG4105CEY	Amp-dependent synthetase and ligase
CCZ27_14040	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
CCZ27_14045	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
CCZ27_14050	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
CCZ27_14055	ENOG4107T8Q	Glycosyl transferase (Group 1
CCZ27_14070	ENOG4105K64	Glycosyl transferase, family 2
CCZ27_14080	ENOG4108IAJ	Nad-dependent epimerase dehydratase
CCZ27_14100	ENOG4105CKK	Glycosyl transferase, family 2
CCZ27_14120	ENOG4107R8N	Glycosyl transferase, family 2
CCZ27_14130	ENOG4107QPH	glycogen) synthase
CCZ27_14140	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CCZ27_14150	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CCZ27_14160	ENOG4105CAQ	asparagine synthetase
CCZ27_14170	ENOG4105DZS	Phenylacetate-CoA ligase
CCZ27_14180	ENOG4107T8Q	Glycosyl transferase (Group 1
CCZ27_14200	ENOG4105CAQ	asparagine synthetase
CCZ27_14205	ENOG4108KMV	Glycosyl transferase (Group 1
CCZ27_14225	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CCZ27_14240	ENOG4108QV3	biosynthesis protein
CCZ27_14265	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CCZ27_14275	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CCZ27_14280	ENOG4107TUY	Histidine kinase
CCZ27_14290	ENOG4105CHM	Aminotransferase
CCZ27_14295	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
CCZ27_14300	ENOG4107W7X	Aldolase
CCZ27_14310	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
CCZ27_14315	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
CCZ27_14320	ENOG4108MTB	glycosyl transferase family
CCZ27_14325	ENOG4105EUB	pirin domain protein
CCZ27_14330	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
CCZ27_14340	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
CCZ27_14355	ENOG4105BZS	acriflavin resistance protein
CCZ27_14365	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CCZ27_14370	ENOG4105CUZ	uba thif-type nad fad binding protein
CCZ27_14390	ENOG4107RDB	Major Facilitator
CCZ27_14395	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CCZ27_14400	ENOG4105CMR	udp-glucose 4-epimerase
CCZ27_14405	ENOG4108ZT0	50S ribosomal protein l17
CCZ27_14410	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CCZ27_14415	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CCZ27_14420	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CCZ27_14425	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CCZ27_14430	ENOG41067V7	50S ribosomal protein L36
CCZ27_14435	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CCZ27_14440	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CCZ27_14445	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CCZ27_14450	ENOG4105VPB	50S ribosomal protein L30
CCZ27_14455	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CCZ27_14460	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CCZ27_14465	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CCZ27_14470	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CCZ27_14475	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CCZ27_14480	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CCZ27_14485	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CCZ27_14490	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CCZ27_14495	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CCZ27_14500	ENOG41084PQ	50s ribosomal protein l29
CCZ27_14505	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CCZ27_14510	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CCZ27_14515	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CCZ27_14520	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CCZ27_14525	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CCZ27_14530	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CCZ27_14535	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CCZ27_14540	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CCZ27_14545	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CCZ27_14550	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CCZ27_14555	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CCZ27_14560	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CCZ27_14565	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CCZ27_14570	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CCZ27_14575	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CCZ27_14580	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CCZ27_14585	ENOG4108VZM	50s ribosomal protein L10
CCZ27_14590	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CCZ27_14605	ENOG4105PM1	preprotein translocase subunit SecE
CCZ27_14615	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CCZ27_14635	ENOG4105CQB	FAD linked oxidase domain protein
CCZ27_14655	ENOG4105WH1	Two component transcriptional regulator luxr family
CCZ27_14665	ENOG4105BZU	Histidine kinase
CCZ27_14685	ENOG4108IV0	ABC, transporter
CCZ27_14705	ENOG4105C0Z	ABC transporter
CCZ27_14710	ENOG4108IQE	Amp-dependent synthetase and ligase
CCZ27_14715	ENOG4106HB6	Alpha beta hydrolase
CCZ27_14725	ENOG4108IV0	ABC, transporter
CCZ27_14745	ENOG4105MI0	Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity)
CCZ27_14750	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
CCZ27_14755	ENOG4108K2P	TRANSCRIPTIONal
CCZ27_14765	ENOG4107R3N	Filamentation induced by cAMP protein fic
CCZ27_14770	ENOG4105D5P	Methylmalonyl-coA mutase
CCZ27_14780	ENOG4105CQZ	Histidine kinase
CCZ27_14785	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CCZ27_14795	ENOG4105CGZ	zinc metallopeptidase
CCZ27_14800	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CCZ27_14805	ENOG4107QX3	carboxylase
CCZ27_14810	ENOG4105DJT	lAO AO transport system ATPase
CCZ27_14815	ENOG4105D5P	Methylmalonyl-coA mutase
CCZ27_14820	ENOG4105DRR	Transcriptional regulator, GntR family
CCZ27_14825	ENOG4105C37	(CBS) domain
CCZ27_14830	ENOG4105C9Q	fumarate hydratase class II
CCZ27_14835	ENOG4107QN1	sodium solute
CCZ27_14840	ENOG41062QD	Membrane
CCZ27_14845	ENOG4105E39	Enoyl-CoA hydratase
CCZ27_14855	ENOG4105DIK	(ABC) transporter
CCZ27_14860	ENOG4105CC5	ABC transporter
CCZ27_14940	ENOG4105C01	Dihydroxy-acid dehydratase
CCZ27_14945	ENOG4108YXG	UPF0502 protein
CCZ27_14950	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CCZ27_14985	ENOG4108UQY	Iron-storage protein
CCZ27_15005	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CCZ27_15010	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CCZ27_15015	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CCZ27_15020	ENOG4108ESX	Receptor
CCZ27_15030	ENOG4107E2E	PKHD-type hydroxylase
CCZ27_15035	ENOG4105CA0	peroxidase
CCZ27_15060	ENOG4107ENK	receptor
CCZ27_15080	ENOG4105CE1	Ferrous iron transport protein b
CCZ27_15155	ENOG4108S2J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CCZ27_15200	ENOG4105GR3	Histidine kinase
CCZ27_15210	ENOG4108JJA	ABC, transporter
CCZ27_15215	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
CCZ27_15245	ENOG4108IJF	Heavy metal efflux pump, CzcA
CCZ27_15260	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CCZ27_15265	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
CCZ27_15270	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
CCZ27_15275	ENOG4105E09	nadh pyrophosphatase
CCZ27_15280	ENOG4107YZX	Universal stress protein
CCZ27_15320	ENOG4105DS1	cytochrome b561
CCZ27_15330	ENOG4105C8Q	Methyl-accepting chemotaxis
CCZ27_15340	ENOG4105CDA	abc transporter atp-binding protein
CCZ27_15345	ENOG4105E5Q	amino acid AbC transporter
CCZ27_15350	ENOG4105E89	ABC transporter
CCZ27_15365	ENOG4105EJC	lysr family transcriptional regulator
CCZ27_15370	ENOG41060W2	glyoxylate carboligase
CCZ27_15375	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
CCZ27_15380	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
CCZ27_15400	ENOG4105CA9	Pyruvate kinase
CCZ27_15475	ENOG4105CMU	LysR family (Transcriptional regulator
CCZ27_15485	ENOG4105BZU	Histidine kinase
CCZ27_15490	ENOG4107QS8	(LipO)protein
CCZ27_15530	ENOG4105K56	Transcriptional regulator
CCZ27_15535	ENOG4105E5M	Multidrug resistance protein D
CCZ27_15540	ENOG4105CC0	LysR family Transcriptional regulator
CCZ27_15555	ENOG4105D2S	major facilitator superfamily
CCZ27_15560	ENOG4105EN6	Membrane
CCZ27_15570	ENOG4108ZCF	integral membrane protein
CCZ27_15575	ENOG4105C10	Electron transfer flavoprotein
CCZ27_15580	ENOG4105BZJ	Electron transfer flavoprotein
CCZ27_15585	ENOG4106YT9	Enoyl-CoA hydratase
CCZ27_15590	ENOG4105JSC	dimethylmenaquinone methyltransferase
CCZ27_15595	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CCZ27_15610	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
CCZ27_15630	ENOG4105C1G	acyl-Coa dehydrogenase
CCZ27_15635	ENOG4105CC9	acyl-Coa dehydrogenase
CCZ27_15640	ENOG4105CD5	CoA-binding domain protein
CCZ27_15650	ENOG4108Z9W	Outer membrane porin
CCZ27_15660	ENOG4105KHM	amidohydrolase 2
CCZ27_15680	ENOG4105E9F	Enoyl-CoA hydratase
CCZ27_15710	ENOG4107SFI	Major Facilitator superfamily
CCZ27_15725	ENOG4105BZU	Histidine kinase
CCZ27_15730	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CCZ27_15735	ENOG4105EUB	pirin domain protein
CCZ27_15750	ENOG4105D6J	arsenicaL-resistance protein
CCZ27_15755	ENOG4108UXE	Protein tyrosine phosphatase
CCZ27_15770	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CCZ27_15775	ENOG4105FUY	alpha subunit
CCZ27_15810	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CCZ27_15830	ENOG4105ER2	Ompa motb domain protein
CCZ27_15845	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CCZ27_15850	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CCZ27_15855	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CCZ27_15860	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CCZ27_15865	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CCZ27_15875	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CCZ27_15890	ENOG4105CEP	NADH dehydrogenase
CCZ27_15920	ENOG4105CHU	acetyl-coa acetyltransferase
CCZ27_15935	ENOG4107U7N	hydantoinase B oxoprolinase
CCZ27_15940	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
CCZ27_15950	ENOG4105RQI	acetone carboxylase gamma subunit
CCZ27_15955	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
CCZ27_15960	ENOG4108RZE	Tetr family transcriptional regulator
CCZ27_15990	ENOG4105D25	secreted protein
CCZ27_16000	ENOG4108KC1	acyl-Coa dehydrogenase
CCZ27_16005	ENOG4108VQN	4-hydroxyphenylacetate 3-monooxygenase reductase
CCZ27_16015	ENOG4108KHK	Glyoxalase Bleomycin resistance protein (Dioxygenase
CCZ27_16025	ENOG4105C7B	Threonine dehydratase
CCZ27_16055	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CCZ27_16060	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CCZ27_16090	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
CCZ27_16095	ENOG4105D49	3-dehydroquinate synthase
CCZ27_16100	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CCZ27_16105	ENOG4105E4G	Type IV pilus
CCZ27_16130	ENOG4108JQC	penicillin-binding protein 1A
CCZ27_16135	ENOG4105XQ6	frataxin-like protein
CCZ27_16145	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CCZ27_16165	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
CCZ27_16170	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
CCZ27_16180	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
CCZ27_16185	ENOG4105RUM	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
CCZ27_16190	ENOG4105CB5	ATP-dependent DNA helicase recG
CCZ27_16195	ENOG4105KME	endoribonuclease L-psp
CCZ27_16210	ENOG4105CGU	Enoyl-CoA hydratase
CCZ27_16215	ENOG4105CHU	acetyl-coa acetyltransferase
CCZ27_16225	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
CCZ27_16235	ENOG4105D2S	major facilitator superfamily
CCZ27_16255	ENOG4105FUY	alpha subunit
CCZ27_16290	ENOG4108JJ7	ABC transporter
CCZ27_16305	ENOG4107RP9	extracellular solute-binding protein, family 3
CCZ27_16310	ENOG4105EAD	ABC transporter
CCZ27_16315	ENOG4105DRP	amino acid AbC transporter
CCZ27_16320	ENOG4105CDA	abc transporter atp-binding protein
CCZ27_16325	ENOG4105HDK	L-asparaginase
CCZ27_16330	ENOG4107R11	Transcriptional regulator
CCZ27_16335	ENOG4107TSN	permease
CCZ27_16355	ENOG4105C11	sulfate adenylyltransferase), subunit 2
CCZ27_16360	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
CCZ27_16365	ENOG4105VEJ	Heat shock protein
CCZ27_16385	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
CCZ27_16390	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
CCZ27_16400	ENOG4107YD3	Thioesterase
CCZ27_16405	ENOG4105E02	MotA TolQ exbB proton channel
CCZ27_16410	ENOG4105M8F	Biopolymer transport protein exbD tolR
CCZ27_16420	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
CCZ27_16425	ENOG4105KCK	Peptidoglycan-associated lipoprotein
CCZ27_16435	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
CCZ27_16440	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
CCZ27_16460	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CCZ27_16475	ENOG4105BZU	Histidine kinase
CCZ27_16480	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CCZ27_16485	ENOG4105BZU	Histidine kinase
CCZ27_16495	ENOG4107RCI	amp-dependent synthetase and ligase
CCZ27_16505	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
CCZ27_16520	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
CCZ27_16540	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
CCZ27_16545	ENOG4105CEY	Amp-dependent synthetase and ligase
CCZ27_16565	ENOG4107QX3	carboxylase
CCZ27_16570	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CCZ27_16605	ENOG4105RD8	TRAP dicarboxylate transporter
CCZ27_16610	ENOG4105CEY	Amp-dependent synthetase and ligase
CCZ27_16615	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CCZ27_16665	ENOG4105C1G	acyl-Coa dehydrogenase
CCZ27_16700	ENOG4105C1G	acyl-Coa dehydrogenase
CCZ27_16705	ENOG4105CHU	acetyl-coa acetyltransferase
CCZ27_16710	ENOG41077A9	carbonic anhydrase
CCZ27_16720	ENOG4108Z6Z	Transcriptional regulator
CCZ27_16730	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
CCZ27_16740	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
CCZ27_16750	ENOG4108Z33	Thiol disulfide Interchange Protein
CCZ27_16760	ENOG4105C75	arginyL-tRNA synthetase
CCZ27_16770	ENOG4105UGU	tonB-dependent Receptor
CCZ27_16785	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
CCZ27_16800	ENOG4105CFP	Peptidase U32
CCZ27_16805	ENOG4106RZ4	Peptidase U32
CCZ27_16810	ENOG4105XPQ	lipid carrier protein
CCZ27_16815	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
CCZ27_16820	ENOG4108ZAI	phosphatidylglycerophosphatase a
CCZ27_16825	ENOG4107TH8	cina domain protein
CCZ27_16830	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CCZ27_16835	ENOG4108004	Modulates RecA activity (By similarity)
CCZ27_16840	ENOG4108IUZ	ABC transporter
CCZ27_16845	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CCZ27_16850	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
CCZ27_16855	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
CCZ27_16860	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
CCZ27_16865	ENOG4105C7B	Threonine dehydratase
CCZ27_16870	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
CCZ27_16875	ENOG4107SC1	transglycosylase
CCZ27_16890	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CCZ27_16900	ENOG4105CYM	Glutathione S-transferase
CCZ27_16905	ENOG410832A	alpha/beta hydrolase fold
CCZ27_16925	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
CCZ27_16935	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
CCZ27_16945	ENOG4105VIF	phosphate starvation-inducible protein
CCZ27_16955	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
CCZ27_16960	ENOG4108J2R	molybdopterin oxidoreductase
CCZ27_16970	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CCZ27_16975	ENOG4105CGK	Exodeoxyribonuclease III
CCZ27_16985	ENOG4108IV0	ABC, transporter
CCZ27_16990	ENOG4105C0Z	ABC transporter
CCZ27_17000	ENOG4105C32	Amino acid ABC transporter (Permease)
CCZ27_17010	ENOG4105TNS	Conserved Protein
CCZ27_17025	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CCZ27_17050	ENOG4108M0I	Transcriptional regulator
CCZ27_17060	ENOG4108ESX	Receptor
CCZ27_17100	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CCZ27_17120	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
CCZ27_17125	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
CCZ27_17130	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
CCZ27_17135	ENOG4105CQM	Urea amidohydrolase subunit alpha
CCZ27_17140	ENOG4105KI2	Urea amidohydrolase subunit beta
CCZ27_17145	ENOG4108YZ9	Urea amidohydrolase subunit gamma
CCZ27_17150	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
CCZ27_17170	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
CCZ27_17175	ENOG4105E0C	molybdate abc transporter
CCZ27_17180	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
CCZ27_17185	ENOG4105F4R	Transcriptional regulator mode
CCZ27_17190	ENOG4105F4R	Transcriptional regulator mode
CCZ27_17195	ENOG4108IV0	ABC, transporter
CCZ27_17200	ENOG4105C0Z	ABC transporter
CCZ27_17205	ENOG4105CNN	ABC, transporter
CCZ27_17210	ENOG4105C32	Amino acid ABC transporter (Permease)
CCZ27_17215	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
CCZ27_17230	ENOG4105CND	Glycosyl transferase, family 2
CCZ27_17240	ENOG4105D4A	Cell wall formation (By similarity)
CCZ27_17245	ENOG4105D64	Mechanosensitive ion channel
CCZ27_17255	ENOG4108UQ8	endoribonuclease L-psp
CCZ27_17265	ENOG4105C31	Tryptophanyl-tRNA synthetase
CCZ27_17280	ENOG4105EHZ	conserved protein UCP016719
CCZ27_17285	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CCZ27_17290	ENOG4105FFC	UPF0187 protein
CCZ27_17295	ENOG4105D22	carbon starvation protein
CCZ27_17300	ENOG4105VCD	cytoplasmic protein
CCZ27_17305	ENOG41080RH	Thioredoxin
CCZ27_17325	ENOG4105DTA	methyltransferase
CCZ27_17345	ENOG4105VEQ	Cold shock protein
CCZ27_17360	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CCZ27_17365	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CCZ27_17380	ENOG4105C3R	Methionine synthase
CCZ27_17405	ENOG4105C32	Amino acid ABC transporter (Permease)
CCZ27_17410	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
CCZ27_17415	ENOG4105C0Z	ABC transporter
CCZ27_17420	ENOG4108IV0	ABC, transporter
CCZ27_17425	ENOG4105C0P	Mg chelatase subunit ChlI
CCZ27_17430	ENOG4105W0Z	cytoplasmic protein
CCZ27_17440	ENOG4108YZA	Nitrogen regulatory protein pii
CCZ27_17445	ENOG4105BZU	Histidine kinase
CCZ27_17455	ENOG4105CIY	formyltetrahydrofolate deformylase
CCZ27_17460	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
CCZ27_17465	ENOG4105CPI	Metal Dependent Phosphohydrolase
CCZ27_17470	ENOG4105C5H	ABC transporter
CCZ27_17500	ENOG4108IEG	Formate dehydrogenase Alpha subunit
CCZ27_17505	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
CCZ27_17520	ENOG4107RT3	EamA-like transporter family
CCZ27_17525	ENOG4105DKK	Benzoate
CCZ27_17535	ENOG41081YB	ApbE family
CCZ27_17540	ENOG4105D7Z	glutathione synthase
CCZ27_17550	ENOG4105C26	Dehydrogenase
CCZ27_17555	ENOG4108UJV	acyl-CoA thioesterase i
CCZ27_17560	ENOG4105XEZ	This methylase recognizes the double-stranded sequence TCGA, causes specific methylation on A-4 on both strands and protects the DNA from cleavage by the
CCZ27_17565	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
CCZ27_17570	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CCZ27_17625	ENOG4105C7J	ABC transporter, permease
CCZ27_17630	ENOG4105D5T	phosphonate abc transporter
CCZ27_17655	ENOG4107QYX	exodeoxyribonuclease v alpha
CCZ27_17660	ENOG4107QKA	exodeoxyribonuclease V beta
CCZ27_17720	ENOG4108U78	Glutathione S-transferase
CCZ27_17725	ENOG4108ZCF	integral membrane protein
CCZ27_17745	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
CCZ27_17760	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CCZ27_17765	ENOG4107YIM	Involved in the transcription termination process (By similarity)
CCZ27_17780	ENOG4105C1J	atp-dependent rna helicase
CCZ27_17785	ENOG4105K70	DNA-binding protein
CCZ27_17795	ENOG4108IV0	ABC, transporter
CCZ27_17800	ENOG4105C0Z	ABC transporter
CCZ27_17810	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
CCZ27_17815	ENOG4105CSU	acyl-Coa dehydrogenase
CCZ27_17830	ENOG4105CHU	acetyl-coa acetyltransferase
CCZ27_17835	ENOG4105E9F	Enoyl-CoA hydratase
CCZ27_17870	ENOG4105C0Z	ABC transporter
CCZ27_17890	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
CCZ27_17900	ENOG4108UKI	Enoyl-CoA hydratase
CCZ27_17905	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CCZ27_17910	ENOG4108ZJI	phenylacetic acid degradation protein
CCZ27_17920	ENOG4105CHU	acetyl-coa acetyltransferase
CCZ27_17930	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
CCZ27_17935	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
CCZ27_17940	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
CCZ27_17945	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
CCZ27_17950	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
CCZ27_17955	ENOG4105CD5	CoA-binding domain protein
CCZ27_17965	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CCZ27_18000	ENOG4108Z0R	Transferase
CCZ27_18010	ENOG4105DR4	Methyltransferase
CCZ27_18020	ENOG4105CEN	a g-specific adenine glycosylase
CCZ27_18030	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
CCZ27_18050	ENOG4105C32	Amino acid ABC transporter (Permease)
CCZ27_18060	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
CCZ27_18065	ENOG4105C5X	domain protein
CCZ27_18070	ENOG4105D82	Glutamate dehydrogenase
CCZ27_18080	ENOG4109066	lysm domain bon superfamily protein
CCZ27_18095	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
CCZ27_18105	ENOG4108JU3	Alkyl hydroperoxide reductase
CCZ27_18110	ENOG4105D3R	alkyl hydroperoxide reductase
CCZ27_18115	ENOG4105DHI	Methyltransferase
CCZ27_18125	ENOG4105DU1	integral membrane protein, terc
CCZ27_18130	ENOG4105VBA	Cytochrome
CCZ27_18140	ENOG4105E3J	oxidoreductase
CCZ27_18145	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CCZ27_18150	ENOG4105E7U	AraC family transcriptional regulator
CCZ27_18180	ENOG4105CS6	Rhs element vgr protein
CCZ27_18200	ENOG4105CS6	Rhs element vgr protein
CCZ27_18205	ENOG4105CNA	YD repeat protein
CCZ27_18245	ENOG4105CFP	Peptidase U32
CCZ27_18250	ENOG4105C5H	ABC transporter
CCZ27_18260	ENOG4108YYC	ycei family
CCZ27_18290	ENOG4105CHU	acetyl-coa acetyltransferase
CCZ27_18295	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
CCZ27_18305	ENOG4108IV0	ABC, transporter
CCZ27_18310	ENOG4105C0Z	ABC transporter
CCZ27_18325	ENOG4107QNJ	CoA-transferase subunit B
CCZ27_18335	ENOG4105C26	Dehydrogenase
CCZ27_18350	ENOG4105JQN	Transcriptional regulator
CCZ27_18360	ENOG4105CS1	NAD(P)H quinone oxidoreductase
CCZ27_18370	ENOG4108YTN	IIa component
CCZ27_18375	ENOG41080Z8	PHOSPHOCARRIER protein
CCZ27_18380	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CCZ27_18390	ENOG4105DFP	Integrase
CCZ27_18425	ENOG4108R8Z	these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression
CCZ27_18625	ENOG41085FC	arsR family transcriptional regulator
CCZ27_18630	ENOG4108YZ3	Glyoxalase Bleomycin resistance protein (Dioxygenase
CCZ27_18640	ENOG4105D6J	arsenicaL-resistance protein
CCZ27_18655	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CCZ27_18695	ENOG4107QJE	Chromosome Partitioning Protein
CCZ27_18710	ENOG4106NZI	LysR family Transcriptional regulator
CCZ27_18715	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CCZ27_18725	ENOG4107QN2	dihydrolipoyl dehydrogenase
CCZ27_18750	ENOG41080HT	Transcriptional regulator, arsr family
CCZ27_18765	ENOG4105DXI	Major Facilitator superfamily
CCZ27_18775	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CCZ27_18780	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CCZ27_18785	ENOG4108JJ8	(ABC) transporter
CCZ27_18790	ENOG4108JJ9	ABC, transporter
CCZ27_18800	ENOG41080HT	Transcriptional regulator, arsr family
CCZ27_18820	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
CCZ27_18835	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CCZ27_18875	ENOG4107SJW	iron permease, FTR1
CCZ27_18890	ENOG4105VUF	Transcriptional regulator
CCZ27_18920	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CCZ27_18925	ENOG4105D3R	alkyl hydroperoxide reductase
CCZ27_18955	ENOG4105DFG	type I secretion outer membrane protein
CCZ27_18960	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
CCZ27_18965	ENOG4106NZI	LysR family Transcriptional regulator
CCZ27_18990	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CCZ27_18995	ENOG4106FI7	cytochrome c-type biogenesis protein
CCZ27_19000	ENOG4105KWW	Biogenesis protein
CCZ27_19005	ENOG4107QX9	Thiol disulfide interChange protein
CCZ27_19010	ENOG4105DA4	cytochrome c-type biogenesis protein
CCZ27_19015	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
CCZ27_19025	ENOG41060IM	Heme exporter protein
CCZ27_19030	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
CCZ27_19035	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
CCZ27_19045	ENOG4105CUW	cytochrome C-TYPE protein
CCZ27_19055	ENOG4105GXZ	Ferredoxin-type protein NapH
CCZ27_19060	ENOG4108BGM	Quinol dehydrogenase periplasmic component
CCZ27_19065	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CCZ27_19075	ENOG4108ZNS	ferredoxin-type protein NapF
CCZ27_19080	ENOG4105WH1	Two component transcriptional regulator luxr family
CCZ27_19085	ENOG4105BZU	Histidine kinase
CCZ27_19095	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
CCZ27_19105	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CCZ27_19110	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CCZ27_19115	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CCZ27_19125	ENOG4105Q26	Siderophore-interacting protein
CCZ27_19130	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CCZ27_19135	ENOG4105BZS	acriflavin resistance protein
CCZ27_19140	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CCZ27_19145	ENOG4105RJZ	Transcriptional regulator
CCZ27_19180	ENOG4107RNH	Outer membrane receptor FepA
CCZ27_19190	ENOG410804D	Sensor Signal Transduction Histidine Kinase
CCZ27_19200	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CCZ27_19205	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CCZ27_19210	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CCZ27_19245	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
CCZ27_19255	ENOG4105DEG	Vwa containing coxe family protein
CCZ27_19270	ENOG4107R7Y	intracellular protease Pfpi family
CCZ27_19280	ENOG4105EQ2	LysR family Transcriptional regulator
CCZ27_19295	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
CCZ27_19305	ENOG4108MEJ	flavin reductase domain protein
CCZ27_19310	ENOG4105EE5	Membrane protein terC
CCZ27_19315	ENOG4105EGI	Transcriptional regulator
CCZ27_19320	ENOG4105CBP	Major Facilitator
CCZ27_19340	ENOG4105D25	secreted protein
CCZ27_19375	ENOG4105E7U	AraC family transcriptional regulator
CCZ27_19385	ENOG4105E7W	lamb ycsf family protein
CCZ27_19390	ENOG4107R7A	Allophanate hydrolase subunit 2
CCZ27_19395	ENOG4105P4J	Allophanate hydrolase, subunit 1
CCZ27_19400	ENOG4105EDV	vault protein
CCZ27_19405	ENOG4105EDV	vault protein
CCZ27_19410	ENOG41081SK	signal peptide protein
CCZ27_19420	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
CCZ27_19430	ENOG4107S52	alpha-2-macroglobulin domain protein
CCZ27_19435	ENOG4108QJJ	Protein of unknown function (DUF1175)
CCZ27_19440	ENOG4107FKF	Uncharacterized protein conserved in bacteria (DUF2138)
CCZ27_19485	ENOG4107QTH	restriction modification system DNA specificity domain
CCZ27_19490	ENOG4105DFS	Conserved Protein
CCZ27_19510	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CCZ27_19590	ENOG4105D70	Integrase catalytic subunit
CCZ27_19595	ENOG4105F5W	AtP-binding protein
CCZ27_19600	ENOG4105CVR	type I restriction-modification system
CCZ27_19605	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
CCZ27_19660	ENOG410829K	Lysine exporter protein (Lyse ygga)
CCZ27_19715	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
CCZ27_19725	ENOG4105DSJ	YicC domain protein
CCZ27_19730	ENOG4107WDG	serine threonine protein kinase
CCZ27_19735	ENOG4108ZF3	Phosphatase
CCZ27_19740	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
CCZ27_19745	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CCZ27_19750	ENOG4105CSA	Coproporphyrinogen iii oxidase
CCZ27_19755	ENOG4105WQ5	TonB family
CCZ27_19760	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
CCZ27_19765	ENOG4105EHG	Permease protein
CCZ27_19770	ENOG4107R4I	Periplasmic binding protein
CCZ27_19780	ENOG4105D05	Receptor
CCZ27_19785	ENOG4105BZU	Histidine kinase
CCZ27_19790	ENOG4108V1U	phospholipid-binding protein
CCZ27_19795	ENOG4105D07	Signal peptide peptidase, SppA
CCZ27_19800	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CCZ27_19805	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CCZ27_19810	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CCZ27_19815	ENOG4105DWV	Homoserine O-trans-acetylase
CCZ27_19820	ENOG4105DWV	Homoserine O-trans-acetylase
CCZ27_19835	ENOG4105EYM	Major Facilitator superfamily
CCZ27_19855	ENOG41077A9	carbonic anhydrase
CCZ27_19860	ENOG4105C25	Primosomal protein n'
CCZ27_19865	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CCZ27_19870	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
CCZ27_19875	ENOG4105C1A	potassium transporter peripheral membrane
CCZ27_19880	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CCZ27_19895	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CCZ27_19900	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
CCZ27_19925	ENOG41082EK	Restriction modification system DNA (Specificity
CCZ27_19940	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CCZ27_19950	ENOG4105DFP	Integrase
CCZ27_19995	ENOG4105DFP	Integrase
CCZ27_20000	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CCZ27_20005	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CCZ27_20010	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CCZ27_20015	ENOG4105X5M	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CCZ27_20025	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CCZ27_20030	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CCZ27_20050	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CCZ27_20055	ENOG4105F2I	Transposase
CCZ27_20095	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CCZ27_20105	ENOG4105UKP	Protein of unknown function (DUF1778)
CCZ27_20115	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CCZ27_20125	ENOG4105W3S	hemerythrin-like, metal-binding protein
CCZ27_20135	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CCZ27_20140	ENOG4105D3G	Pseudouridine synthase
CCZ27_20145	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CCZ27_20165	ENOG4108N3W	hemolysin secretion protein
CCZ27_20180	ENOG4105DHJ	ABC, transporter
CCZ27_20195	ENOG4105D0S	secretion protein (HlyD
CCZ27_20200	ENOG4105CJ1	ABC, transporter
CCZ27_20205	ENOG4105CMI	transporter
CCZ27_20210	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
CCZ27_20240	ENOG4105E9K	Isocitrate dehydrogenase
CCZ27_20250	ENOG4105BZU	Histidine kinase
CCZ27_20275	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
CCZ27_20280	ENOG4105DH7	May be involved in recombination (By similarity)
CCZ27_20290	ENOG4105I08	Pseudouridine synthase
CCZ27_20300	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CCZ27_20315	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CCZ27_20325	ENOG4105KA7	cytochrome C
CCZ27_20330	ENOG4105C8Q	Methyl-accepting chemotaxis
CCZ27_20335	ENOG4105C0H	protease
CCZ27_20340	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CCZ27_20355	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CCZ27_20360	ENOG4108RPN	Protein smg homolog
CCZ27_20365	ENOG4105C79	DNA protecting protein DprA
CCZ27_20375	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CCZ27_20380	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CCZ27_20390	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CCZ27_20395	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CCZ27_20400	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
CCZ27_20405	ENOG4108MG3	formate dehydrogenase
CCZ27_20410	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
CCZ27_20435	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CCZ27_20465	ENOG4108RZE	Tetr family transcriptional regulator
CCZ27_20470	ENOG4108IV0	ABC, transporter
CCZ27_20475	ENOG4105C0Z	ABC transporter
CCZ27_20480	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
CCZ27_20485	ENOG4105C32	Amino acid ABC transporter (Permease)
CCZ27_20500	ENOG4105CEY	Amp-dependent synthetase and ligase
CCZ27_20510	ENOG4108TKH	Nitroreductase
CCZ27_20525	ENOG4105FUY	alpha subunit
CCZ27_20535	ENOG4105DP0	ferredoxin-NADP reductase
CCZ27_20545	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CCZ27_20565	ENOG4108Q89	anthranilate 1,2-dioxygenase large subunit
CCZ27_20575	ENOG4105CHR	reductase
CCZ27_20585	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
CCZ27_20605	ENOG4105C0Z	ABC transporter
CCZ27_20610	ENOG4108IV0	ABC, transporter
CCZ27_20660	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
CCZ27_20670	ENOG4105D5K	Hemolysin activator protein
CCZ27_20760	ENOG4105W1Y	Transcriptional regulator
CCZ27_20805	ENOG4105CHR	reductase
CCZ27_20870	ENOG4105CPQ	Dehydrogenase
CCZ27_20885	ENOG4107QHF	type ii secretion system protein e
CCZ27_20890	ENOG4105EM7	Selenocysteine-specific translation elongation factor
CCZ27_20900	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
CCZ27_20910	ENOG4105CBN	LysR family transcriptional regulator
CCZ27_20915	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
CCZ27_20920	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
CCZ27_20925	ENOG4105CQ0	ABC transporter
CCZ27_20940	ENOG4105CKT	filamentous hemagglutinin
CCZ27_20965	ENOG4105FYV	Amp nucleosidase
CCZ27_20970	ENOG4105E39	Enoyl-CoA hydratase
CCZ27_21000	ENOG4105BZ1	(ABC) transporter
CCZ27_21010	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CCZ27_21015	ENOG4105J0Q	Transcriptional regulator
CCZ27_21020	ENOG4105C0Z	ABC transporter
CCZ27_21025	ENOG4108IV0	ABC, transporter
CCZ27_21035	ENOG4105C32	Amino acid ABC transporter (Permease)
CCZ27_21045	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CCZ27_21050	ENOG4105CY2	Citrate transporter
CCZ27_21055	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
CCZ27_21060	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CCZ27_21065	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CCZ27_21070	ENOG4107QJE	Chromosome Partitioning Protein
CCZ27_21085	ENOG4105FA0	parb-like partition protein
CCZ27_21095	ENOG4107S74	Lysophospholipid transporter LplT
CCZ27_21110	ENOG41082BM	Transcriptional regulator, arsr family
CCZ27_21120	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
CCZ27_21125	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CCZ27_21130	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CCZ27_21135	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CCZ27_21140	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CCZ27_21145	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CCZ27_21150	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CCZ27_21155	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CCZ27_21170	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CCZ27_21180	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CCZ27_21185	ENOG4105BZU	Histidine kinase
CCZ27_21200	ENOG4105E7A	Glutamine amidotransferase
CCZ27_21205	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CCZ27_21215	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CCZ27_21220	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CCZ27_21225	ENOG4105DFF	Rod shape-determining protein mreb
CCZ27_21240	ENOG4105CJN	penicillin-binding protein
CCZ27_21245	ENOG4105CNI	cell division protein FtsW
CCZ27_21250	ENOG4105K6T	rare lipoprotein A
CCZ27_21255	ENOG4105DZ1	carboxypeptidase
CCZ27_21260	ENOG4105F0I	Aminotransferase
CCZ27_21265	ENOG4108Z43	UPF0250 protein
CCZ27_21270	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CCZ27_21275	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CCZ27_21295	ENOG4105C4R	Atp-dependent dna helicase
CCZ27_21310	ENOG4105DXI	Major Facilitator superfamily
CCZ27_21315	ENOG4105K78	MarR family Transcriptional regulator
CCZ27_21340	ENOG4107RSS	Hydrogenase accessory protein HypB
CCZ27_21375	ENOG4108HM4	ABC transporter
CCZ27_21380	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CCZ27_21385	ENOG4105F38	ABC transporter, permease
CCZ27_21390	ENOG4105D38	putrescine abc transporter
CCZ27_21400	ENOG4108RH0	Crea protein
CCZ27_21415	ENOG4105F0V	Cell wall hydrolase
CCZ27_21440	ENOG4105BZU	Histidine kinase
CCZ27_21450	ENOG4107ZXU	DSBA oxidoreductase
CCZ27_21470	ENOG4105BZU	Histidine kinase
CCZ27_21485	ENOG4105EYH	Exonuclease
CCZ27_21520	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
CCZ27_21525	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CCZ27_21530	ENOG4105BZS	acriflavin resistance protein
CCZ27_21535	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CCZ27_21540	ENOG4105CKI	cobalamin synthesis protein
CCZ27_21550	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
CCZ27_21575	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
CCZ27_21585	ENOG4105C7I	Dehydrogenase
CCZ27_21595	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
CCZ27_21600	ENOG4107RNH	Outer membrane receptor FepA
CCZ27_21610	ENOG4105BZU	Histidine kinase
CCZ27_21615	ENOG4105DSY	exodeoxyribonuclease V, gamma
CCZ27_21625	ENOG4108JJ6	Type I secretion system ATPase
CCZ27_21630	ENOG4108JJ6	Type I secretion system ATPase
CCZ27_21635	ENOG4107QZV	Type I secretion membrane fusion protein
CCZ27_21655	ENOG4105WD1	Membrane
CCZ27_21660	ENOG4105IPI	Membrane
CCZ27_21685	ENOG4105CA0	peroxidase
CCZ27_21690	ENOG4105HEI	LysR family (Transcriptional regulator
CCZ27_21700	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
CCZ27_21705	ENOG4105VTW	prevent-host-death family
CCZ27_21715	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
CCZ27_21730	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CCZ27_21735	ENOG4105K8R	UPF0145 protein
CCZ27_21740	ENOG4105CDY	transcriptional regulatory protein
CCZ27_21745	ENOG4105D7A	ATP-binding protein
CCZ27_21755	ENOG4105BZU	Histidine kinase
CCZ27_21760	ENOG4105SYT	Methylenetetrahydrofolate reductase
CCZ27_21765	ENOG4105DX0	Hemolysin A
CCZ27_21770	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
CCZ27_21775	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CCZ27_21785	ENOG4105D1S	lipid A biosynthesis
CCZ27_21790	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CCZ27_21800	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CCZ27_21815	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CCZ27_21820	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CCZ27_21830	ENOG4105C03	ribonuclease
CCZ27_21835	ENOG4108Z03	MAF-like protein
CCZ27_21840	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
CCZ27_21845	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
CCZ27_21850	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CCZ27_21865	ENOG4105CUV	Homoserine Kinase
CCZ27_21880	ENOG4108URH	decarboxylase
CCZ27_21885	ENOG4105C2M	dna polymerase I
CCZ27_21925	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CCZ27_21935	ENOG4105D3Q	Sugar transferase
CCZ27_21940	ENOG4107WZ3	Transferase
CCZ27_21970	ENOG4107TYR	Glycosyl Transferase
CCZ27_21985	ENOG4107EF8	Glycosyl transferase (Group 1
CCZ27_21995	ENOG4105CG5	Glycosyl transferase (Group 1
CCZ27_22000	ENOG4105CG5	Glycosyl transferase (Group 1
CCZ27_22005	ENOG4107XU6	Glycosyl transferase (Group 1
CCZ27_22020	ENOG4105BZ1	(ABC) transporter
CCZ27_22030	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
CCZ27_22045	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
CCZ27_22050	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
CCZ27_22055	ENOG4108M3P	Membrane
CCZ27_22060	ENOG4105D0M	Protease HtpX homolog
CCZ27_22065	ENOG4105DC8	reductase
CCZ27_22070	ENOG4108YZT	Adenosylcobinamide kinase
CCZ27_22085	ENOG4105EHG	Permease protein
CCZ27_22090	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
CCZ27_22095	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CCZ27_22100	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
CCZ27_22105	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CCZ27_22140	ENOG4105DJ4	phosphatidylserine decarboxylase
CCZ27_22150	ENOG4105CYC	Transferase
CCZ27_22155	ENOG4105C1J	atp-dependent rna helicase
CCZ27_22165	ENOG4105EFT	decarboxylase
CCZ27_22170	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
CCZ27_22175	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CCZ27_22180	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
CCZ27_22185	ENOG4105BZU	Histidine kinase
CCZ27_22190	ENOG4105W2Z	cytochrome C, class I
CCZ27_22195	ENOG4105BZU	Histidine kinase
CCZ27_22200	ENOG4105BZU	Histidine kinase
CCZ27_22205	ENOG4105D58	Diguanylate phosphodiesterase
CCZ27_22210	ENOG4108EX3	reductase
CCZ27_22220	ENOG4108YXA	Membrane
CCZ27_22225	ENOG4105BZU	Histidine kinase
CCZ27_22235	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
CCZ27_22240	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
CCZ27_22245	ENOG4105CZX	twitching motility protein
CCZ27_22250	ENOG4105CZX	twitching motility protein
CCZ27_22255	ENOG4105DFA	alanine racemase domain protein
CCZ27_22260	ENOG4105II7	pyrroline-5-carboxylate reductase
CCZ27_22265	ENOG4108VIA	integral membrane protein
CCZ27_22270	ENOG4105VZ9	UPF0235 protein
CCZ27_22275	ENOG4105CD3	dihydroorotase
CCZ27_22280	ENOG4105CXT	aspartate transcarbamylase
CCZ27_22285	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
CCZ27_22290	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CCZ27_22295	ENOG4108UJU	UPF0301 protein
CCZ27_22300	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CCZ27_22305	ENOG4105CBS	Chea signal transduction histidine kinase
CCZ27_22310	ENOG4105C8Q	Methyl-accepting chemotaxis
CCZ27_22320	ENOG4105M3Z	response regulator
CCZ27_22325	ENOG4108UNF	response regulator
CCZ27_22330	ENOG4105VCQ	rubredoxin
CCZ27_22340	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CCZ27_22345	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CCZ27_22350	ENOG4105BZU	Histidine kinase
CCZ27_22355	ENOG4107ZHV	Transcriptional regulator
CCZ27_22365	ENOG4105CJW	magnesium transporter
CCZ27_22370	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
CCZ27_22385	ENOG4105FR1	rard protein
CCZ27_22395	ENOG4105IPS	esterase
CCZ27_22400	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CCZ27_22405	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
CCZ27_22410	ENOG4105CQ7	ATP-dependent helicase
CCZ27_22420	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
CCZ27_22430	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CCZ27_22435	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CCZ27_22440	ENOG4105CDU	Replicative dna helicase
CCZ27_22470	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CCZ27_22495	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CCZ27_22500	ENOG4105JQN	Transcriptional regulator
CCZ27_22505	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CCZ27_22535	ENOG4105CHJ	isochorismatase hydrolase
CCZ27_22600	ENOG4105W5Q	DNA repair protein (RadC
CCZ27_22630	ENOG4105F5W	AtP-binding protein
CCZ27_22690	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
CCZ27_22695	ENOG4106TD9	Diguanylate cyclase
CCZ27_22700	ENOG4105BZU	Histidine kinase
CCZ27_22765	ENOG4108ZQS	transposase
CCZ27_22770	ENOG4108YXQ	IS66 Orf2 family protein
CCZ27_22775	ENOG4105E5H	Transposase
CCZ27_22795	ENOG4108RAV	Conserved protein
CCZ27_22825	ENOG4108WIW	Aspartyl protease
CCZ27_22835	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
CCZ27_22930	ENOG4105W1Y	Transcriptional regulator
CCZ27_22945	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CCZ27_22970	ENOG4105EWK	phytoene
CCZ27_22985	ENOG4105E5H	Transposase
CCZ27_23115	ENOG4105RWS	endonuclease I
CCZ27_23120	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
CCZ27_23125	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CCZ27_23160	ENOG4105UKP	Protein of unknown function (DUF1778)
CCZ27_23175	ENOG4105CAF	HipA N-terminal domain protein