locus-tag	class	description
LQF09_00035	COG0515	serine threonine protein kinase
LQF09_00035	COG2815	serine threonine protein kinase
LQF09_00050	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LQF09_00120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LQF09_00165	COG5002	protein histidine kinase activity
LQF09_00180	COG1742	UPF0060 membrane protein
LQF09_00190	COG5002	protein histidine kinase activity
LQF09_00215	COG2132	Multicopper oxidase
LQF09_00235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQF09_00240	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQF09_00345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LQF09_00350	COG0501	Belongs to the peptidase M48B family
LQF09_00365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LQF09_00375	COG0542	response to heat
LQF09_00380	COG0071	Belongs to the small heat shock protein (HSP20) family
LQF09_00465	COG2433	Pfam Transposase IS66
LQF09_00485	COG0655	NAD(P)H dehydrogenase (quinone) activity
LQF09_00510	COG4942	peptidase
LQF09_00530	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LQF09_00540	COG0564	pseudouridine synthase activity
LQF09_00550	COG1451	nucleotide metabolic process
LQF09_00580	COG1192	Involved in chromosome partitioning
LQF09_00630	COG0700	Nucleoside recognition
LQF09_00640	COG0477	Major facilitator Superfamily
LQF09_00645	COG3264	Mechanosensitive ion channel
LQF09_00645	COG1196	nuclear chromosome segregation
LQF09_00675	COG0642	Histidine kinase
LQF09_00685	COG0045	succinate-CoA ligase (ADP-forming) activity
LQF09_00695	COG1607	acyl-coa hydrolase
LQF09_00725	COG3179	chitinase
LQF09_00740	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LQF09_00745	COG1929	Belongs to the glycerate kinase type-1 family
LQF09_00750	COG3835	regulator
LQF09_00760	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LQF09_00775	COG0840	transmembrane signaling receptor activity
LQF09_00780	COG2974	May be involved in recombination
LQF09_00790	COG1187	pseudouridine synthase activity
LQF09_00805	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LQF09_00820	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LQF09_00830	COG3909	cytochrome
LQF09_00840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LQF09_00845	COG4206	TonB-dependent receptor
LQF09_00855	COG0783	Belongs to the Dps family
LQF09_00860	COG1522	sequence-specific DNA binding
LQF09_00875	COG2922	Belongs to the Smg family
LQF09_00880	COG0758	DNA mediated transformation
LQF09_00885	COG1652	LysM domain
LQF09_00890	COG0242	peptide deformylase activity
LQF09_00895	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LQF09_00900	COG0501	Belongs to the peptidase M48B family
LQF09_00905	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LQF09_00915	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LQF09_00920	COG3639	organic phosphonate transmembrane transporter activity
LQF09_00925	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LQF09_00940	COG0252	asparaginase activity
LQF09_00950	COG1115	amino acid carrier protein
LQF09_00960	COG1024	Enoyl-CoA hydratase
LQF09_00980	COG1132	(ABC) transporter
LQF09_00985	COG1793	dna ligase
LQF09_01025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LQF09_01055	COG2201	protein-glutamate methylesterase activity
LQF09_01065	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
LQF09_01070	COG0840	transmembrane signaling receptor activity
LQF09_01075	COG0835	chemotaxis
LQF09_01080	COG0840	transmembrane signaling receptor activity
LQF09_01085	COG2198	Histidine kinase
LQF09_01085	COG0643	Histidine kinase
LQF09_01100	COG0745	RESPONSE REGULATOR receiver
LQF09_01105	COG0445	tRNA wobble uridine modification
LQF09_01110	COG0357	Ribosomal RNA small subunit methyltransferase G
LQF09_01115	COG1192	Involved in chromosome partitioning
LQF09_01120	COG1475	DNA binding
LQF09_01135	COG0356	it plays a direct role in the translocation of protons across the membrane
LQF09_01145	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LQF09_01150	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LQF09_01155	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LQF09_01160	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LQF09_01165	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LQF09_01170	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LQF09_01185	COG2226	methyltransferase
LQF09_01195	COG0745	RESPONSE REGULATOR receiver
LQF09_01215	COG0121	glutamine amidotransferase
LQF09_01220	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LQF09_01230	COG0154	amidase activity
LQF09_01235	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LQF09_01240	COG1077	Cell shape determining protein MreB Mrl
LQF09_01255	COG0768	penicillin binding
LQF09_01260	COG0772	Belongs to the SEDS family
LQF09_01270	COG1686	Belongs to the peptidase S11 family
LQF09_01280	COG2921	Belongs to the UPF0250 family
LQF09_01285	COG0321	lipoyl(octanoyl) transferase activity
LQF09_01290	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LQF09_01305	COG0210	DNA helicase
LQF09_01325	COG2194	sulfuric ester hydrolase activity
LQF09_01330	COG5002	protein histidine kinase activity
LQF09_01340	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LQF09_01355	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LQF09_01360	COG4569	acetaldehyde dehydrogenase (acetylating) activity
LQF09_01375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LQF09_01380	COG1012	belongs to the aldehyde dehydrogenase family
LQF09_01420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQF09_01425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQF09_01440	COG0300	oxidoreductase activity
LQF09_01450	COG1028	Short-chain dehydrogenase reductase Sdr
LQF09_01505	COG2433	Pfam Transposase IS66
LQF09_01530	COG4372	Transposase
LQF09_01535	COG3436	PFAM IS66 Orf2 family protein
LQF09_01545	COG2814	Major facilitator Superfamily
LQF09_01555	COG1960	acyl-CoA dehydrogenase activity
LQF09_01570	COG1960	acyl-CoA dehydrogenase activity
LQF09_01575	COG1960	acyl-CoA dehydrogenase activity
LQF09_01580	COG1960	acyl-CoA dehydrogenase activity
LQF09_01585	COG2814	Major facilitator Superfamily
LQF09_01610	COG1028	Short-chain dehydrogenase reductase Sdr
LQF09_01625	COG0628	permease
LQF09_01635	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LQF09_01715	COG0318	PFAM AMP-dependent synthetase and ligase
LQF09_01720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LQF09_01725	COG1960	acyl-CoA dehydrogenase activity
LQF09_01735	COG1250	3-hydroxyacyl-CoA dehydrogenase
LQF09_01735	COG1024	Enoyl-CoA hydratase
LQF09_01740	COG0183	Belongs to the thiolase family
LQF09_01745	COG1309	transcriptional regulator
LQF09_01760	COG1960	acyl-CoA dehydrogenase activity
LQF09_01770	COG0633	Ferredoxin
LQF09_01800	COG2086	electron transfer activity
LQF09_01825	COG0300	oxidoreductase activity
LQF09_01845	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LQF09_01850	COG0583	DNA-binding transcription factor activity
LQF09_01855	COG2095	MarC family integral membrane protein
LQF09_01890	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
LQF09_01895	COG0415	Belongs to the DNA photolyase family
LQF09_01905	COG0415	Belongs to the DNA photolyase family
LQF09_01910	COG0697	spore germination
LQF09_01920	COG0322	excinuclease ABC activity
LQF09_01930	COG0438	transferase activity, transferring glycosyl groups
LQF09_01945	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LQF09_01950	COG0826	peptidase U32
LQF09_01975	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LQF09_01980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LQF09_01990	COG0559	Belongs to the binding-protein-dependent transport system permease family
LQF09_02020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LQF09_02035	COG0513	Belongs to the DEAD box helicase family
LQF09_02060	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
LQF09_02070	COG2204	response regulator
LQF09_02075	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LQF09_02075	COG1024	Enoyl-CoA hydratase
LQF09_02080	COG0309	Hydrogenase expression formation protein (HypE)
LQF09_02085	COG0409	Hydrogenase expression formation protein
LQF09_02090	COG0298	carbon dioxide binding
LQF09_02095	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LQF09_02105	COG0375	protein maturation
LQF09_02110	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
LQF09_02125	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LQF09_02130	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
LQF09_02135	COG5557	Pfam Polysulphide reductase, NrfD
LQF09_02140	COG0437	4 iron, 4 sulfur cluster binding
LQF09_02145	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
LQF09_02160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LQF09_02165	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LQF09_02190	COG4232	protein-disulfide reductase activity
LQF09_02235	COG2026	Addiction module toxin, RelE StbE family
LQF09_02250	COG1487	ribonuclease activity
LQF09_02285	COG1487	ribonuclease activity
LQF09_02305	COG0625	glutathione transferase activity
LQF09_02345	COG2308	Evidence 4 Homologs of previously reported genes of
LQF09_02370	COG0582	viral genome integration into host DNA
LQF09_02380	COG3093	addiction module antidote protein HigA
LQF09_02435	COG1525	nuclease
LQF09_02465	COG0583	DNA-binding transcription factor activity
LQF09_02475	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LQF09_02480	COG0583	DNA-binding transcription factor activity
LQF09_02485	COG4974	Belongs to the 'phage' integrase family
LQF09_02490	COG4974	Belongs to the 'phage' integrase family
LQF09_02495	COG4974	Belongs to the 'phage' integrase family
LQF09_02525	COG4453	Protein conserved in bacteria
LQF09_02540	COG3209	COG3209 Rhs family protein
LQF09_02565	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LQF09_02600	COG3436	PFAM IS66 Orf2 family protein
LQF09_02610	COG4974	Belongs to the 'phage' integrase family
LQF09_02640	COG4372	Transposase
LQF09_02680	COG2433	Pfam Transposase IS66
LQF09_02730	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LQF09_02740	COG0217	transcriptional regulatory protein
LQF09_02745	COG0433	COG0433 Predicted ATPase
LQF09_02790	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LQF09_02800	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LQF09_02805	COG0530	calcium, potassium:sodium antiporter activity
LQF09_02810	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LQF09_02820	COG1560	Kdo2-lipid A biosynthetic process
LQF09_02825	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LQF09_02835	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LQF09_02850	COG2255	four-way junction helicase activity
LQF09_02855	COG0632	four-way junction helicase activity
LQF09_02875	COG1530	ribonuclease E activity
LQF09_02880	COG0424	maF-like protein
LQF09_02885	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LQF09_02890	COG0799	negative regulation of ribosome biogenesis
LQF09_02895	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LQF09_02910	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LQF09_02930	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LQF09_02930	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LQF09_02935	COG1132	(ABC) transporter
LQF09_02940	COG4636	protein conserved in cyanobacteria
LQF09_02955	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LQF09_02995	COG0482	sulfurtransferase activity
LQF09_03000	COG0463	Glycosyl transferase, family 2
LQF09_03000	COG1216	Glycosyl transferase, family 2
LQF09_03030	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LQF09_03040	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LQF09_03045	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LQF09_03060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LQF09_03115	COG0406	alpha-ribazole phosphatase activity
LQF09_03130	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LQF09_03135	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LQF09_03145	COG4206	TonB-dependent receptor
LQF09_03150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LQF09_03155	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LQF09_03160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LQF09_03160	COG1648	precorrin-2 dehydrogenase activity
LQF09_03180	COG0688	phosphatidylethanolamine metabolic process
LQF09_03185	COG0516	GMP reductase activity
LQF09_03185	COG0517	IMP dehydrogenase activity
LQF09_03190	COG0427	acetyl-CoA hydrolase
LQF09_03195	COG4191	Histidine kinase
LQF09_03195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LQF09_03210	COG0513	Belongs to the DEAD box helicase family
LQF09_03220	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LQF09_03230	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LQF09_03235	COG1492	cobalamin metabolic process
LQF09_03240	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LQF09_03240	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LQF09_03255	COG5002	protein histidine kinase activity
LQF09_03260	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LQF09_03265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LQF09_03265	COG0543	2 iron, 2 sulfur cluster binding
LQF09_03275	COG1981	membrane
LQF09_03285	COG3852	Histidine kinase
LQF09_03290	COG1763	Mo-molybdopterin cofactor biosynthetic process
LQF09_03300	COG0746	molybdenum cofactor guanylyltransferase activity
LQF09_03340	COG0437	4 iron, 4 sulfur cluster binding
LQF09_03390	COG0762	integral membrane protein
LQF09_03400	COG0540	Belongs to the ATCase OTCase family
LQF09_03405	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LQF09_03410	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LQF09_03415	COG1678	Uncharacterized ACR, COG1678
LQF09_03425	COG0415	Belongs to the DNA photolyase family
LQF09_03430	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LQF09_03435	COG2198	Histidine kinase
LQF09_03435	COG0643	Histidine kinase
LQF09_03440	COG0840	transmembrane signaling receptor activity
LQF09_03460	COG1773	rubredoxin
LQF09_03470	COG0352	thiamine-phosphate diphosphorylase activity
LQF09_03475	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LQF09_03480	COG2239	Acts as a magnesium transporter
LQF09_03485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LQF09_03490	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LQF09_03500	COG0557	exoribonuclease II activity
LQF09_03510	COG2226	methyltransferase
LQF09_03515	COG3150	esterase
LQF09_03520	COG1968	undecaprenyl-diphosphatase activity
LQF09_03530	COG1618	nucleotide phosphatase activity, acting on free nucleotides
LQF09_03530	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LQF09_03535	COG1643	Atp-dependent helicase
LQF09_03545	COG0360	Binds together with S18 to 16S ribosomal RNA
LQF09_03550	COG2965	DNA replication, synthesis of RNA primer
LQF09_03555	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LQF09_03560	COG0359	binds to the 23S rRNA
LQF09_03565	COG0305	Participates in initiation and elongation during chromosome replication
LQF09_03595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LQF09_03600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LQF09_03610	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LQF09_03620	COG0352	thiamine-phosphate diphosphorylase activity
LQF09_03625	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LQF09_03630	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
LQF09_03635	COG0237	dephospho-CoA kinase activity
LQF09_03645	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LQF09_03650	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LQF09_03655	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LQF09_03655	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LQF09_03665	COG3852	Histidine kinase
LQF09_03675	COG0174	glutamine synthetase
LQF09_03680	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LQF09_03690	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LQF09_03695	COG3568	Endonuclease Exonuclease Phosphatase
LQF09_03700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LQF09_03705	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LQF09_03710	COG3245	cytochrome
LQF09_03765	COG4263	nitrous-oxide reductase activity
LQF09_03775	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LQF09_03785	COG0668	transmembrane transport
LQF09_03800	COG0012	GTP binding
LQF09_03810	COG0193	aminoacyl-tRNA hydrolase activity
LQF09_03815	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LQF09_03820	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LQF09_03830	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LQF09_03835	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LQF09_03845	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LQF09_03850	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LQF09_03855	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LQF09_03860	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LQF09_03865	COG0742	ribosomal rna small subunit methyltransferase
LQF09_03870	COG0612	Peptidase, M16
LQF09_03875	COG0612	Peptidase, M16
LQF09_03885	COG2884	Cell division ATP-binding protein ftsE
LQF09_03890	COG2177	Part of the ABC transporter FtsEX involved in
LQF09_03900	COG3634	alkyl hydroperoxide reductase activity
LQF09_03905	COG1132	(ABC) transporter
LQF09_03910	COG5001	Diguanylate cyclase
LQF09_03910	COG3300	MHYT domain
LQF09_03935	COG0583	DNA-binding transcription factor activity
LQF09_03965	COG0625	glutathione transferase activity
LQF09_03970	COG2814	Major facilitator Superfamily
LQF09_03975	COG1024	Enoyl-CoA hydratase
LQF09_03980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LQF09_03995	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LQF09_04005	COG0583	DNA-binding transcription factor activity
LQF09_04010	COG3959	Transketolase, thiamine diphosphate binding domain
LQF09_04015	COG3958	Transketolase
LQF09_04020	COG1028	Short-chain dehydrogenase reductase Sdr
LQF09_04025	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LQF09_04030	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LQF09_04035	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LQF09_04045	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LQF09_04120	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LQF09_04125	COG1702	phosphate starvation-inducible protein PhoH
LQF09_04130	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LQF09_04135	COG4535	Mg2 and Co2 transporter CorC
LQF09_04140	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LQF09_04145	COG0752	glycyl-tRNA synthetase alpha subunit
LQF09_04150	COG0751	glycine-tRNA ligase activity
LQF09_04155	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LQF09_04160	COG0204	Acyl-transferase
LQF09_04165	COG2154	pterin-4-alpha-carbinolamine dehydratase
LQF09_04175	COG1024	Enoyl-CoA hydratase
LQF09_04180	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LQF09_04215	COG1459	type II secretion system
LQF09_04220	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LQF09_04225	COG1450	Type ii and iii secretion system protein
LQF09_04230	COG1127	ABC transporter
LQF09_04235	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LQF09_04240	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LQF09_04260	COG1131	(ABC) transporter
LQF09_04265	COG0842	Transport permease protein
LQF09_04270	COG0271	Belongs to the BolA IbaG family
LQF09_04275	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LQF09_04280	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LQF09_04285	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LQF09_04290	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LQF09_04295	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LQF09_04300	COG0131	Imidazoleglycerol-phosphate dehydratase
LQF09_04305	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LQF09_04310	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LQF09_04315	COG0107	imidazoleglycerol-phosphate synthase activity
LQF09_04320	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LQF09_04325	COG0140	phosphoribosyl-ATP diphosphatase activity
LQF09_04335	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LQF09_04340	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LQF09_04345	COG0805	protein transport
LQF09_04355	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LQF09_04370	COG0045	succinate-CoA ligase (ADP-forming) activity
LQF09_04375	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LQF09_04380	COG1716	ATPase activity
LQF09_04385	COG1234	tRNA 3'-trailer cleavage
LQF09_04390	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LQF09_04395	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LQF09_04400	COG0546	phosphoglycolate phosphatase activity
LQF09_04415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LQF09_04420	COG0134	indole-3-glycerol-phosphate synthase activity
LQF09_04430	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LQF09_04440	COG1522	sequence-specific DNA binding
LQF09_04445	COG0733	neurotransmitter:sodium symporter activity
LQF09_04475	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LQF09_04480	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LQF09_04485	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
LQF09_04515	COG0109	protoheme IX farnesyltransferase activity
LQF09_04520	COG0514	ATP-dependent DNA helicase (RecQ)
LQF09_04540	COG1469	GTP cyclohydrolase I activity
LQF09_04555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LQF09_04575	COG4221	oxidoreductase activity
LQF09_04585	COG1999	signal sequence binding
LQF09_04665	COG0741	lytic transglycosylase activity
LQF09_04670	COG0436	Aminotransferase
LQF09_04675	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LQF09_04680	COG0280	phosphate acetyltransferase
LQF09_04680	COG0281	malic enzyme
LQF09_04700	COG2111	Na H antiporter
LQF09_04700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LQF09_04705	COG1006	Multisubunit Na H antiporter MnhC subunit
LQF09_04710	COG0651	ATP synthesis coupled electron transport
LQF09_04715	COG1863	multisubunit Na H antiporter MnhE subunit
LQF09_04720	COG2212	antiporter activity
LQF09_04725	COG1320	monovalent cation:proton antiporter activity
LQF09_04730	COG1187	pseudouridine synthase activity
LQF09_04735	COG1320	monovalent cation:proton antiporter activity
LQF09_04740	COG2212	antiporter activity
LQF09_04745	COG1863	multisubunit Na H antiporter MnhE subunit
LQF09_04750	COG0651	ATP synthesis coupled electron transport
LQF09_04755	COG1006	Multisubunit Na H antiporter MnhC subunit
LQF09_04760	COG2111	Na H antiporter
LQF09_04760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LQF09_04770	COG0577	efflux transmembrane transporter activity
LQF09_04770	COG1136	(ABC) transporter
LQF09_04775	COG0577	efflux transmembrane transporter activity
LQF09_04775	COG1136	(ABC) transporter
LQF09_04780	COG0577	efflux transmembrane transporter activity
LQF09_04780	COG1136	(ABC) transporter
LQF09_04805	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LQF09_04810	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LQF09_04815	COG3047	cAMP biosynthetic process
LQF09_04815	COG2885	chlorophyll binding
LQF09_04820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LQF09_04825	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LQF09_04830	COG0351	phosphomethylpyrimidine kinase
LQF09_04840	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LQF09_04865	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LQF09_04880	COG0537	adenosine 5'-monophosphoramidase activity
LQF09_04885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LQF09_04900	COG2264	protein methyltransferase activity
LQF09_04905	COG0439	Biotin carboxylase
LQF09_04910	COG0511	ligase activity, forming carbon-carbon bonds
LQF09_04915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LQF09_04925	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LQF09_04930	COG2823	Periplasmic or secreted lipoprotein
LQF09_04935	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LQF09_04940	COG0792	nuclease activity
LQF09_04950	COG0418	dihydroorotase activity
LQF09_04965	COG2001	Belongs to the MraZ family
LQF09_04970	COG0275	rRNA processing
LQF09_04975	COG3116	cell division
LQF09_04985	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LQF09_04990	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LQF09_04995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LQF09_05000	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LQF09_05005	COG0772	Belongs to the SEDS family
LQF09_05010	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LQF09_05015	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LQF09_05020	COG1181	Belongs to the D-alanine--D-alanine ligase family
LQF09_05025	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LQF09_05040	COG0235	Class ii aldolase
LQF09_05045	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LQF09_05050	COG0436	Aminotransferase
LQF09_05070	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LQF09_05080	COG1136	(ABC) transporter
LQF09_05080	COG0577	efflux transmembrane transporter activity
LQF09_05105	COG0489	protein tyrosine kinase activity
LQF09_05115	COG3267	Type II secretory pathway component ExeA
LQF09_05115	COG3409	Peptidoglycan-binding domain 1 protein
LQF09_05140	COG0438	transferase activity, transferring glycosyl groups
LQF09_05145	COG0367	asparagine synthase
LQF09_05150	COG0438	transferase activity, transferring glycosyl groups
LQF09_05155	COG0438	transferase activity, transferring glycosyl groups
LQF09_05185	COG0367	asparagine synthase
LQF09_05205	COG0297	glycogen (starch) synthase activity
LQF09_05215	COG0463	Glycosyl transferase, family 2
LQF09_05230	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LQF09_05240	COG3119	arylsulfatase activity
LQF09_05245	COG1216	Glycosyl transferase, family 2
LQF09_05255	COG1215	transferase activity, transferring glycosyl groups
LQF09_05270	COG1215	transferase activity, transferring glycosyl groups
LQF09_05275	COG0367	asparagine synthase
LQF09_05280	COG3754	Rhamnan synthesis protein F
LQF09_05295	COG0297	glycogen (starch) synthase activity
LQF09_05305	COG2151	metal-sulfur cluster biosynthetic enzyme
LQF09_05310	COG5652	VanZ like family
LQF09_05320	COG0019	diaminopimelate decarboxylase activity
LQF09_05325	COG0318	PFAM AMP-dependent synthetase and ligase
LQF09_05335	COG3273	potassium ion transport
LQF09_05335	COG0471	metal ion transport
LQF09_05345	COG0175	sulfate reduction
LQF09_05360	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LQF09_05365	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LQF09_05370	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LQF09_05375	COG0723	plastoquinol--plastocyanin reductase activity
LQF09_05380	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LQF09_05385	COG2857	Cytochrome c1
LQF09_05390	COG0625	glutathione transferase activity
LQF09_05395	COG2969	positive regulation of protein catabolic process
LQF09_05400	COG2703	oxygen carrier activity
LQF09_05405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LQF09_05410	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LQF09_05420	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LQF09_05425	COG1984	allophanate hydrolase subunit 2
LQF09_05430	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LQF09_05440	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LQF09_05455	COG1760	l-serine dehydratase
LQF09_05460	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LQF09_05465	COG0459	protein refolding
LQF09_05475	COG0642	Histidine kinase
LQF09_05485	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LQF09_05490	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LQF09_05495	COG2890	protein-(glutamine-N5) methyltransferase activity
LQF09_05500	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LQF09_05525	COG3001	Fructosamine kinase
LQF09_05530	COG2815	serine threonine protein kinase
LQF09_05530	COG0515	serine threonine protein kinase
LQF09_05535	COG0165	Argininosuccinate lyase
LQF09_05540	COG3275	phosphorelay sensor kinase activity
LQF09_05550	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LQF09_05555	COG0181	hydroxymethylbilane synthase activity
LQF09_05570	COG0408	coproporphyrinogen oxidase activity
LQF09_05575	COG0151	Belongs to the GarS family
LQF09_05585	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LQF09_05605	COG2011	ABC-type metal ion transport system permease component
LQF09_05615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LQF09_05620	COG0006	proline dipeptidase activity
LQF09_05625	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LQF09_05635	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LQF09_05640	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LQF09_05645	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LQF09_05650	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LQF09_05680	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LQF09_05720	COG0126	phosphoglycerate kinase activity
LQF09_05725	COG3954	Phosphoribulokinase
LQF09_05730	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LQF09_05750	COG0583	DNA-binding transcription factor activity
LQF09_05765	COG0126	phosphoglycerate kinase activity
LQF09_05770	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LQF09_05775	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LQF09_05780	COG0840	transmembrane signaling receptor activity
LQF09_05790	COG0483	inositol monophosphate 1-phosphatase activity
LQF09_05795	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LQF09_05805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LQF09_05805	COG1042	CoA-binding domain protein
LQF09_05805	COG0045	succinate-CoA ligase (ADP-forming) activity
LQF09_05810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LQF09_05815	COG2151	metal-sulfur cluster biosynthetic enzyme
LQF09_05820	COG3396	Phenylacetate-CoA oxygenase
LQF09_05825	COG3460	Phenylacetate-CoA oxygenase
LQF09_05830	COG3396	Phenylacetate-CoA oxygenase
LQF09_05840	COG0183	Belongs to the thiolase family
LQF09_05850	COG2050	protein possibly involved in aromatic compounds catabolism
LQF09_05855	COG1250	3-hydroxyacyl-CoA dehydrogenase
LQF09_05860	COG1024	Enoyl-CoA hydratase
LQF09_05870	COG3327	negative regulation of DNA-templated transcription, initiation
LQF09_05910	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LQF09_05910	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LQF09_05915	COG5002	protein histidine kinase activity
LQF09_05915	COG3447	MASE1 domain protein
LQF09_05915	COG5001	Diguanylate cyclase
LQF09_05920	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LQF09_05925	COG0704	Plays a role in the regulation of phosphate uptake
LQF09_05930	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LQF09_05945	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LQF09_05965	COG2226	methyltransferase
LQF09_05970	COG1040	competence protein
LQF09_05975	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LQF09_05980	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LQF09_05990	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LQF09_06000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LQF09_06005	COG0640	Transcriptional regulator
LQF09_06010	COG4942	peptidase
LQF09_06015	COG0793	Belongs to the peptidase S41A family
LQF09_06025	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LQF09_06030	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LQF09_06030	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LQF09_06035	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LQF09_06040	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LQF09_06060	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LQF09_06065	COG0312	modulator of DNA gyrase
LQF09_06070	COG3028	Belongs to the UPF0307 family
LQF09_06075	COG0521	Mo-molybdopterin cofactor biosynthetic process
LQF09_06085	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
LQF09_06090	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LQF09_06095	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LQF09_06100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LQF09_06105	COG2096	Adenosyltransferase
LQF09_06120	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LQF09_06125	COG1192	Involved in chromosome partitioning
LQF09_06130	COG0280	phosphate acetyltransferase
LQF09_06130	COG0281	malic enzyme
LQF09_06150	COG0659	secondary active sulfate transmembrane transporter activity
LQF09_06155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LQF09_06155	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LQF09_06165	COG0489	protein tyrosine kinase activity
LQF09_06170	COG0717	Belongs to the dCTP deaminase family
LQF09_06185	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LQF09_06220	COG2030	dehydratase
LQF09_06225	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LQF09_06230	COG3852	Histidine kinase
LQF09_06235	COG2204	response regulator
LQF09_06245	COG0741	lytic transglycosylase activity
LQF09_06245	COG1196	nuclear chromosome segregation
LQF09_06245	COG0739	heme binding
LQF09_06270	COG0488	(ABC) transporter
LQF09_06280	COG1704	LemA family
LQF09_06290	COG0604	alcohol dehydrogenase
LQF09_06300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LQF09_06320	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LQF09_06345	COG0457	Tetratricopeptide repeat
LQF09_06345	COG3118	belongs to the thioredoxin family
LQF09_06350	COG1819	glycosyl
LQF09_06355	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LQF09_06360	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LQF09_06365	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LQF09_06370	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LQF09_06385	COG0277	FAD linked oxidase domain protein
LQF09_06390	COG0277	FAD linked oxidase domain protein
LQF09_06395	COG0247	lactate metabolic process
LQF09_06400	COG0631	protein serine/threonine phosphatase activity
LQF09_06410	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LQF09_06425	COG5001	Diguanylate cyclase
LQF09_06430	COG0513	Belongs to the DEAD box helicase family
LQF09_06435	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
LQF09_06440	COG0667	Aldo Keto reductase
LQF09_06450	COG1653	transport
LQF09_06455	COG0142	geranyltranstransferase activity
LQF09_06550	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LQF09_06560	COG1012	belongs to the aldehyde dehydrogenase family
LQF09_06570	COG3284	Transcriptional regulator
LQF09_06575	COG0501	Belongs to the peptidase M48B family
LQF09_06580	COG1704	LemA family
LQF09_06585	COG4772	TonB-dependent receptor
LQF09_06605	COG0583	DNA-binding transcription factor activity
LQF09_06615	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LQF09_06620	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
LQF09_06630	COG0535	radical SAM domain protein
LQF09_06645	COG3851	Histidine kinase
LQF09_06665	COG1116	anion transmembrane transporter activity
LQF09_06670	COG1131	(ABC) transporter
LQF09_06740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LQF09_06755	COG0702	epimerase
LQF09_06760	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
LQF09_06765	COG0189	ligase activity
LQF09_06770	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
LQF09_06900	COG1229	Formylmethanofuran dehydrogenase subunit A
LQF09_06905	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
LQF09_06930	COG2831	hemolysin activation secretion protein
LQF09_06940	COG3383	formate dehydrogenase (NAD+) activity
LQF09_06955	COG3284	Transcriptional regulator
LQF09_07005	COG3851	Histidine kinase
LQF09_07030	COG3284	Transcriptional regulator
LQF09_07040	COG2414	aldehyde ferredoxin oxidoreductase
LQF09_07045	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LQF09_07065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LQF09_07080	COG2204	response regulator
LQF09_07110	COG2204	response regulator
LQF09_07115	COG0315	cyclic pyranopterin monophosphate synthase activity
LQF09_07120	COG4783	chaperone-mediated protein folding
LQF09_07125	COG0425	Belongs to the sulfur carrier protein TusA family
LQF09_07130	COG0525	valine-tRNA ligase activity
LQF09_07145	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LQF09_07150	COG0795	lipopolysaccharide-transporting ATPase activity
LQF09_07155	COG0795	lipopolysaccharide-transporting ATPase activity
LQF09_07160	COG0335	large ribosomal subunit rRNA binding
LQF09_07165	COG0336	Belongs to the RNA methyltransferase TrmD family
LQF09_07170	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LQF09_07175	COG0228	four-way junction DNA binding
LQF09_07195	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LQF09_07200	COG1183	phosphatidylcholine synthase activity
LQF09_07205	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LQF09_07210	COG0440	acetolactate synthase activity
LQF09_07215	COG0028	Belongs to the TPP enzyme family
LQF09_07225	COG0308	aminopeptidase N
LQF09_07230	COG0517	IMP dehydrogenase activity
LQF09_07230	COG0516	GMP reductase activity
LQF09_07235	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LQF09_07240	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LQF09_07245	COG1428	Deoxynucleoside kinase
LQF09_07260	COG0617	tRNA 3'-terminal CCA addition
LQF09_07275	COG0628	permease
LQF09_07280	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LQF09_07290	COG0475	glutathione-regulated potassium exporter activity
LQF09_07290	COG0589	response to stress
LQF09_07310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQF09_07315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQF09_07320	COG2841	Protein conserved in bacteria
LQF09_07330	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LQF09_07335	COG5001	Diguanylate cyclase
LQF09_07340	COG1238	metal cluster binding
LQF09_07345	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LQF09_07355	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LQF09_07365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LQF09_07365	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LQF09_07380	COG0720	synthase
LQF09_07410	COG1294	oxidase, subunit
LQF09_07450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LQF09_07450	COG4191	Histidine kinase
LQF09_07460	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LQF09_07470	COG0564	pseudouridine synthase activity
LQF09_07485	COG3243	poly(R)-hydroxyalkanoic acid synthase
LQF09_07490	COG1028	Short-chain dehydrogenase reductase Sdr
LQF09_07505	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LQF09_07510	COG1752	Esterase of the alpha-beta hydrolase superfamily
LQF09_07515	COG0277	FAD linked oxidase domain protein
LQF09_07550	COG1250	3-hydroxyacyl-CoA dehydrogenase
LQF09_07555	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LQF09_07570	COG0517	IMP dehydrogenase activity
LQF09_07570	COG0617	tRNA 3'-terminal CCA addition
LQF09_07570	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LQF09_07575	COG0318	PFAM AMP-dependent synthetase and ligase
LQF09_07580	COG0028	Belongs to the TPP enzyme family
LQF09_07585	COG0440	acetolactate synthase activity
LQF09_07590	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LQF09_07595	COG2814	Major facilitator Superfamily
LQF09_07605	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LQF09_07615	COG0066	3-isopropylmalate dehydratase activity
LQF09_07620	COG0473	3-isopropylmalate dehydrogenase activity
LQF09_07640	COG0101	tRNA pseudouridine synthase activity
LQF09_07645	COG0135	phosphoribosylanthranilate isomerase activity
LQF09_07650	COG0133	tryptophan synthase activity
LQF09_07655	COG0159	tryptophan synthase activity
LQF09_07660	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LQF09_07665	COG0285	dihydrofolate synthase activity
LQF09_07670	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LQF09_07690	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LQF09_07695	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LQF09_07700	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LQF09_07705	COG0215	cysteine-tRNA ligase activity
LQF09_07710	COG0484	heat shock protein binding
LQF09_07715	COG0443	Heat shock 70 kDa protein
LQF09_07720	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LQF09_07735	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LQF09_07745	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LQF09_07750	COG0287	Prephenate dehydrogenase
LQF09_07755	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LQF09_07765	COG0776	regulation of translation
LQF09_07775	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LQF09_07805	COG2261	transglycosylase associated protein
LQF09_07815	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LQF09_07820	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LQF09_07825	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LQF09_07830	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LQF09_07835	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LQF09_07840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LQF09_07840	COG0072	phenylalanine-tRNA ligase activity
LQF09_07845	COG0776	regulation of translation
LQF09_07860	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LQF09_07865	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LQF09_07875	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LQF09_07885	COG2951	lytic endotransglycosylase activity
LQF09_07900	COG0714	Associated with various cellular activities
LQF09_07905	COG0123	including yeast histone deacetylase and acetoin utilization protein
LQF09_07910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LQF09_07915	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LQF09_07925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LQF09_07935	COG0156	8-amino-7-oxononanoate synthase activity
LQF09_07940	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LQF09_07945	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LQF09_07980	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LQF09_08000	COG1191	sigma factor activity
LQF09_08005	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LQF09_08010	COG1360	Flagellar Motor Protein
LQF09_08020	COG3290	protein histidine kinase activity
LQF09_08020	COG0840	transmembrane signaling receptor activity
LQF09_08050	COG2747	anti-sigma28 factor FlgM
LQF09_08060	COG1815	bacterial-type flagellum-dependent cell motility
LQF09_08065	COG1558	bacterial-type flagellum-dependent cell motility
LQF09_08070	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LQF09_08080	COG4787	bacterial-type flagellum-dependent cell motility
LQF09_08085	COG4786	Flagellar basal body rod
LQF09_08090	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LQF09_08095	COG1706	bacterial-type flagellum-dependent cell motility
LQF09_08100	COG3951	Flagellar rod assembly protein muramidase FlgJ
LQF09_08100	COG1705	Flagellar rod assembly protein muramidase FlgJ
LQF09_08140	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LQF09_08145	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LQF09_08165	COG1157	protein secretion by the type III secretion system
LQF09_08180	COG1766	The M ring may be actively involved in energy transduction
LQF09_08195	COG1677	Flagellar hook-basal body complex protein FliE
LQF09_08200	COG0582	viral genome integration into host DNA
LQF09_08255	COG3311	Transcriptional regulator
LQF09_08305	COG4191	Histidine kinase
LQF09_08350	COG4774	siderophore transport
LQF09_08355	COG0019	diaminopimelate decarboxylase activity
LQF09_08365	COG4264	IucA IucC family
LQF09_08370	COG4264	IucA IucC family
LQF09_08375	COG2814	Major facilitator Superfamily
LQF09_08380	COG4264	IucA IucC family
LQF09_08385	COG2423	ornithine cyclodeaminase activity
LQF09_08390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LQF09_08410	COG3655	Transcriptional regulator
LQF09_08430	COG2890	protein-(glutamine-N5) methyltransferase activity
LQF09_08445	COG1063	alcohol dehydrogenase
LQF09_08450	COG0215	cysteine-tRNA ligase activity
LQF09_08455	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LQF09_08460	COG0735	belongs to the Fur family
LQF09_08465	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LQF09_08470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LQF09_08475	COG0505	Belongs to the CarA family
LQF09_08485	COG3135	benzoate transporter
LQF09_08495	COG0114	fumarate hydratase activity
LQF09_08500	COG1230	cation diffusion facilitator family transporter
LQF09_08505	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
LQF09_08510	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
LQF09_08515	COG2257	FlhB HrpN YscU SpaS Family
LQF09_08530	COG1516	flagellar protein fliS
LQF09_08555	COG1216	Glycosyl transferase, family 2
LQF09_08560	COG3551	Protein conserved in bacteria
LQF09_08570	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LQF09_08600	COG0651	ATP synthesis coupled electron transport
LQF09_08605	COG0651	ATP synthesis coupled electron transport
LQF09_08610	COG0651	ATP synthesis coupled electron transport
LQF09_08620	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LQF09_08620	COG2111	Na H antiporter
LQF09_08630	COG1320	monovalent cation:proton antiporter activity
LQF09_08650	COG2032	superoxide dismutase activity
LQF09_08660	COG0584	glycerophosphoryl diester phosphodiesterase
LQF09_08665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LQF09_08675	COG2951	lytic endotransglycosylase activity
LQF09_08680	COG2186	Transcriptional regulator
LQF09_08685	COG1620	l-lactate permease
LQF09_08690	COG0247	lactate metabolic process
LQF09_08705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LQF09_08715	COG0402	S-adenosylhomocysteine deaminase activity
LQF09_08720	COG2815	serine threonine protein kinase
LQF09_08720	COG0515	serine threonine protein kinase
LQF09_08725	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LQF09_08730	COG1420	regulation of RNA biosynthetic process
LQF09_08735	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LQF09_08740	COG0497	DNA recombination
LQF09_08750	COG0735	belongs to the Fur family
LQF09_08755	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LQF09_08760	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LQF09_08765	COG0784	Response regulator, receiver
LQF09_08765	COG2205	protein histidine kinase activity
LQF09_08765	COG5002	protein histidine kinase activity
LQF09_08770	COG0505	Belongs to the CarA family
LQF09_08775	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LQF09_08780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LQF09_08785	COG1534	Rna-binding protein
LQF09_08790	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LQF09_08795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LQF09_08800	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LQF09_08805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LQF09_08815	COG0573	inorganic phosphate transmembrane transporter activity
LQF09_08825	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LQF09_08835	COG0656	L-ascorbic acid biosynthetic process
LQF09_08845	COG1879	ABC-type sugar transport system periplasmic component
LQF09_08855	COG0861	Integral membrane protein TerC family
LQF09_08865	COG0166	Belongs to the GPI family
LQF09_08870	COG0625	glutathione transferase activity
LQF09_08895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LQF09_08900	COG1595	DNA-templated transcription, initiation
LQF09_08910	COG1252	NADH dehydrogenase
LQF09_08930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LQF09_08945	COG0659	secondary active sulfate transmembrane transporter activity
LQF09_08965	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LQF09_08975	COG0640	Transcriptional regulator
LQF09_08980	COG0798	PFAM Bile acid sodium symporter
LQF09_08990	COG0431	NADPH-dependent FMN reductase
LQF09_09000	COG4628	conserved protein (DUF2132)
LQF09_09030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LQF09_09080	COG2081	HI0933 family
LQF09_09100	COG0822	iron-sulfur transferase activity
LQF09_09105	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LQF09_09110	COG0719	Fe-S assembly protein
LQF09_09115	COG0396	ATPase activity
LQF09_09120	COG0719	Fe-S assembly protein
LQF09_09125	COG1959	2 iron, 2 sulfur cluster binding
LQF09_09135	COG0625	glutathione transferase activity
LQF09_09140	COG0534	Mate efflux family protein
LQF09_09145	COG1490	D-aminoacyl-tRNA deacylase activity
LQF09_09155	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LQF09_09175	COG1902	pentaerythritol trinitrate reductase activity
LQF09_09180	COG1979	alcohol dehydrogenase
LQF09_09185	COG1309	transcriptional regulator
LQF09_09190	COG2814	Major facilitator Superfamily
LQF09_09195	COG0587	DNA-directed DNA polymerase activity
LQF09_09205	COG4120	Belongs to the binding-protein-dependent transport system permease family
LQF09_09210	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LQF09_09215	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LQF09_09240	COG2197	response regulator
LQF09_09245	COG4585	Histidine kinase
LQF09_09250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LQF09_09250	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LQF09_09260	COG2226	methyltransferase
LQF09_09265	COG1968	undecaprenyl-diphosphatase activity
LQF09_09270	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LQF09_09330	COG2099	Precorrin-6x reductase
LQF09_09345	COG2875	Belongs to the precorrin methyltransferase family
LQF09_09360	COG1196	nuclear chromosome segregation
LQF09_09365	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LQF09_09460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LQF09_09495	COG1595	DNA-templated transcription, initiation
LQF09_09510	COG4372	Transposase
LQF09_09515	COG3436	PFAM IS66 Orf2 family protein
LQF09_09530	COG2433	Pfam Transposase IS66
LQF09_09570	COG3712	iron ion homeostasis
LQF09_09575	COG1595	DNA-templated transcription, initiation
LQF09_09585	COG3712	iron ion homeostasis
LQF09_09590	COG1595	DNA-templated transcription, initiation
LQF09_09645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQF09_09650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQF09_09670	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LQF09_09680	COG0850	regulation of cytokinetic process
LQF09_09685	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LQF09_09690	COG1393	Belongs to the ArsC family
LQF09_09695	COG2183	response to ionizing radiation
LQF09_09700	COG1032	radical SAM domain protein
LQF09_09715	COG1136	(ABC) transporter
LQF09_09725	COG0658	competence protein
LQF09_09725	COG2333	competence protein COMEC
LQF09_09735	COG1162	GTPase activity
LQF09_09740	COG0501	Belongs to the peptidase M48B family
LQF09_09745	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LQF09_09755	COG0254	rRNA binding
LQF09_09760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LQF09_09770	COG3012	SEC-C Motif Domain Protein
LQF09_09770	COG3318	Belongs to the UPF0149 family
LQF09_09775	COG0727	PFAM Uncharacterised protein family (UPF0153)
LQF09_09785	COG0579	oxidoreductase
LQF09_09790	COG0523	cobalamin synthesis protein
LQF09_09810	COG3012	SEC-C Motif Domain Protein
LQF09_09835	COG1061	Type III restriction enzyme res subunit
LQF09_09845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LQF09_09865	COG0583	DNA-binding transcription factor activity
LQF09_09870	COG0473	3-isopropylmalate dehydrogenase activity
LQF09_09890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LQF09_09895	COG0189	ligase activity
LQF09_09900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LQF09_09905	COG4215	(ABC) transporter
LQF09_09910	COG4160	amino acid transport
LQF09_09920	COG2814	Major facilitator Superfamily
LQF09_09925	COG0583	DNA-binding transcription factor activity
LQF09_09935	COG0039	L-malate dehydrogenase activity
LQF09_09940	COG2188	Transcriptional regulator
LQF09_09955	COG1053	succinate dehydrogenase
LQF09_09960	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LQF09_09965	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LQF09_09970	COG0372	Belongs to the citrate synthase family
LQF09_09975	COG0567	Dehydrogenase, E1 component
LQF09_09980	COG0508	dehydrogenase complex catalyzes the overall conversion of
LQF09_09985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LQF09_09990	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LQF09_10060	COG0668	transmembrane transport
LQF09_10065	COG1199	ATP-dependent helicase activity
LQF09_10070	COG1763	Mo-molybdopterin cofactor biosynthetic process
LQF09_10075	COG0303	'Molybdopterin
LQF09_10080	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LQF09_10085	COG0314	molybdopterin synthase activity
LQF09_10110	COG0471	metal ion transport
LQF09_10110	COG3273	potassium ion transport
LQF09_10130	COG0657	acetylesterase activity
LQF09_10140	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LQF09_10150	COG1376	ErfK ybiS ycfS ynhG family protein
LQF09_10170	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LQF09_10175	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LQF09_10190	COG0084	hydrolase, TatD family'
LQF09_10290	COG0534	Mate efflux family protein
LQF09_10310	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LQF09_10320	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LQF09_10325	COG1047	Peptidyl-prolyl cis-trans
LQF09_10335	COG1388	LysM domain
LQF09_10335	COG0741	lytic transglycosylase activity
LQF09_10340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LQF09_10350	COG0328	RNA-DNA hybrid ribonuclease activity
LQF09_10360	COG4109	DRTGG domain
LQF09_10375	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LQF09_10385	COG0483	inositol monophosphate 1-phosphatase activity
LQF09_10395	COG1045	serine acetyltransferase
LQF09_10405	COG1104	cysteine desulfurase activity
LQF09_10410	COG1104	cysteine desulfurase activity
LQF09_10415	COG0822	iron-sulfur transferase activity
LQF09_10425	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LQF09_10430	COG0443	Heat shock 70 kDa protein
LQF09_10435	COG0633	Ferredoxin
LQF09_10445	COG0745	RESPONSE REGULATOR receiver
LQF09_10455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LQF09_10465	COG2171	N-acyltransferase activity
LQF09_10470	COG0436	Aminotransferase
LQF09_10475	COG1196	nuclear chromosome segregation
LQF09_10485	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LQF09_10505	COG2862	Uncharacterized protein family, UPF0114
LQF09_10510	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LQF09_10515	COG0024	Methionine aminopeptidase
LQF09_10520	COG0052	Belongs to the universal ribosomal protein uS2 family
LQF09_10525	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LQF09_10530	COG0528	UMP kinase activity
LQF09_10535	COG0233	cytoplasmic translational termination
LQF09_10540	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LQF09_10545	COG0575	Belongs to the CDS family
LQF09_10550	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LQF09_10570	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LQF09_10575	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LQF09_10580	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LQF09_10585	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LQF09_10590	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LQF09_10595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LQF09_10605	COG3022	response to hydroperoxide
LQF09_10610	COG2866	Carboxypeptidase
LQF09_10615	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LQF09_10625	COG1562	ergosterol biosynthetic process
LQF09_10630	COG1136	(ABC) transporter
LQF09_10665	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LQF09_10670	COG3383	formate dehydrogenase (NAD+) activity
LQF09_10675	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
LQF09_10680	COG3259	Nickel-dependent hydrogenase
LQF09_10705	COG1573	uracil-dna glycosylase
LQF09_10710	COG0456	acetyltransferase
LQF09_10730	COG2205	protein histidine kinase activity
LQF09_10735	COG2917	probably involved in intracellular septation
LQF09_10740	COG2350	Protein conserved in bacteria
LQF09_10750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LQF09_10755	COG1960	acyl-CoA dehydrogenase activity
LQF09_10780	COG0084	hydrolase, TatD family'
LQF09_10790	COG0318	PFAM AMP-dependent synthetase and ligase
LQF09_10805	COG1127	ABC transporter
LQF09_10810	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LQF09_10815	COG0248	Ppx GppA phosphatase
LQF09_10820	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LQF09_10825	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LQF09_10830	COG3228	Belongs to the MtfA family
LQF09_10850	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LQF09_10855	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LQF09_10860	COG1355	regulation of microtubule-based process
LQF09_10865	COG2078	PFAM AMMECR1 domain protein
LQF09_10885	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LQF09_10895	COG0598	Magnesium transport protein CorA
LQF09_10905	COG2433	Pfam Transposase IS66
LQF09_10925	COG0583	DNA-binding transcription factor activity
LQF09_10935	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LQF09_10965	COG1484	DNA-dependent DNA replication
LQF09_10985	COG2818	Glycosylase
LQF09_11035	COG1278	Cold shock
LQF09_11040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LQF09_11045	COG0560	Phosphoserine phosphatase
LQF09_11050	COG4181	ATPase activity
LQF09_11060	COG0709	Synthesizes selenophosphate from selenide and ATP
LQF09_11065	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
LQF09_11075	COG4251	negative regulation of phosphorylation
LQF09_11080	COG0045	succinate-CoA ligase (ADP-forming) activity
LQF09_11080	COG1042	CoA-binding domain protein
LQF09_11080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LQF09_11125	COG2204	response regulator
LQF09_11130	COG0446	pyridine nucleotide-disulphide oxidoreductase
LQF09_11145	COG1242	4 iron, 4 sulfur cluster binding
LQF09_11150	COG0322	excinuclease ABC activity
LQF09_11155	COG1472	Belongs to the glycosyl hydrolase 3 family
LQF09_11160	COG0736	holo-[acyl-carrier-protein] synthase activity
LQF09_11165	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LQF09_11170	COG1381	Involved in DNA repair and RecF pathway recombination
LQF09_11175	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LQF09_11180	COG0571	ribonuclease III activity
LQF09_11190	COG0681	Belongs to the peptidase S26 family
LQF09_11195	COG0481	GTPase activity
LQF09_11205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LQF09_11230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LQF09_11240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LQF09_11245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LQF09_11255	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LQF09_11260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LQF09_11265	COG0416	fatty acid biosynthetic process
LQF09_11270	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LQF09_11280	COG0424	maF-like protein
LQF09_11285	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LQF09_11295	COG0564	pseudouridine synthase activity
LQF09_11300	COG1530	ribonuclease E activity
LQF09_11305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LQF09_11310	COG0556	nucleotide-excision repair
LQF09_11330	COG1067	ATP-dependent peptidase activity
LQF09_11335	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LQF09_11360	COG0438	transferase activity, transferring glycosyl groups
LQF09_11395	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LQF09_11410	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LQF09_11415	COG1473	amidohydrolase
LQF09_11420	COG0513	Belongs to the DEAD box helicase family
LQF09_11445	COG1024	Enoyl-CoA hydratase
LQF09_11460	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LQF09_11465	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LQF09_11470	COG0740	serine-type endopeptidase activity
LQF09_11475	COG0544	peptidyl-prolyl cis-trans isomerase activity
LQF09_11480	COG2766	serine protein kinase
LQF09_11485	COG2718	Belongs to the UPF0229 family
LQF09_11490	COG2719	SpoVR family
LQF09_11495	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LQF09_11495	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LQF09_11520	COG3384	dioxygenase
LQF09_11525	COG3038	cytochrome b561
LQF09_11530	COG2353	YceI-like domain
LQF09_11535	COG2353	YceI-like domain
LQF09_11545	COG3360	Dodecin
LQF09_11555	COG2258	MOSC domain
LQF09_11565	COG0436	Aminotransferase
LQF09_11575	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LQF09_11580	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LQF09_11595	COG0791	NLP P60 protein
LQF09_11605	COG1840	ABC-type Fe3 transport system, periplasmic component
LQF09_11615	COG1178	ABC-type Fe3 transport system permease component
LQF09_11620	COG3842	ATPase activity
LQF09_11625	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LQF09_11630	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LQF09_11635	COG0167	dihydroorotate dehydrogenase activity
LQF09_11650	COG2010	Cytochrome c
LQF09_11660	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LQF09_11700	COG2200	EAL domain
LQF09_11715	COG0535	radical SAM domain protein
LQF09_11730	COG1522	sequence-specific DNA binding
LQF09_11735	COG3391	amine dehydrogenase activity
LQF09_11760	COG2010	Cytochrome c
LQF09_11765	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LQF09_11765	COG1648	precorrin-2 dehydrogenase activity
LQF09_11795	COG2358	TRAP transporter, solute receptor (TAXI family
LQF09_11800	COG4251	negative regulation of phosphorylation
LQF09_11805	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LQF09_11805	COG0519	Catalyzes the synthesis of GMP from XMP
LQF09_11820	COG2914	Belongs to the UPF0125 (RnfH) family
LQF09_11830	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LQF09_11835	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LQF09_11840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LQF09_11845	COG0601	transmembrane transport
LQF09_11860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LQF09_11870	COG0542	response to heat
LQF09_11875	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LQF09_11880	COG2176	DNA-directed DNA polymerase activity
LQF09_11880	COG5002	protein histidine kinase activity
LQF09_11885	COG0745	RESPONSE REGULATOR receiver
LQF09_11890	COG5002	protein histidine kinase activity
LQF09_11900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LQF09_11920	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LQF09_11930	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LQF09_11940	COG0183	Belongs to the thiolase family
LQF09_11945	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LQF09_11950	COG0494	nUDIX hydrolase
LQF09_11970	COG4966	pilus assembly protein PilW
LQF09_12005	COG1666	GTP binding
LQF09_12010	COG3123	guanosine phosphorylase activity
LQF09_12020	COG0137	argininosuccinate synthase activity
LQF09_12025	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LQF09_12030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LQF09_12040	COG0268	Binds directly to 16S ribosomal RNA
LQF09_12045	COG0728	peptidoglycan biosynthetic process
LQF09_12050	COG0583	DNA-binding transcription factor activity
LQF09_12065	COG0386	Belongs to the glutathione peroxidase family
LQF09_12070	COG0488	(ABC) transporter
LQF09_12075	COG0501	Belongs to the peptidase M48B family
LQF09_12080	COG4269	membrane
LQF09_12120	COG4796	Type ii and iii secretion system protein
LQF09_12180	COG0697	spore germination
LQF09_12215	COG2205	protein histidine kinase activity
LQF09_12215	COG0784	Response regulator, receiver
LQF09_12230	COG3530	Putative quorum-sensing-regulated virulence factor
LQF09_12240	COG1204	response to ionizing radiation
LQF09_12270	COG1127	ABC transporter
LQF09_12275	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LQF09_12280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQF09_12285	COG1129	ABC transporter
LQF09_12285	COG0842	Transport permease protein
LQF09_12290	COG0842	Transport permease protein
LQF09_12310	COG0438	transferase activity, transferring glycosyl groups
LQF09_12315	COG2989	Protein conserved in bacteria
LQF09_12320	COG3108	Peptidase M15
LQF09_12335	COG2133	pyrroloquinoline quinone binding
LQF09_12345	COG0826	peptidase U32
LQF09_12375	COG3045	CreA protein
LQF09_12400	COG0802	atpase or kinase
LQF09_12405	COG0860	N-Acetylmuramoyl-L-alanine amidase
LQF09_12410	COG0196	riboflavin kinase activity
LQF09_12415	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LQF09_12420	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LQF09_12425	COG1047	Peptidyl-prolyl cis-trans
LQF09_12430	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LQF09_12440	COG1722	exodeoxyribonuclease VII activity
LQF09_12445	COG0142	geranyltranstransferase activity
LQF09_12450	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LQF09_12455	COG1469	GTP cyclohydrolase I activity
LQF09_12460	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LQF09_12480	COG0484	heat shock protein binding
LQF09_12495	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LQF09_12505	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LQF09_12510	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LQF09_12515	COG1674	ftsk spoiiie
LQF09_12525	COG0492	ferredoxin-NADP+ reductase activity
LQF09_12530	COG2840	Smr protein MutS2
LQF09_12540	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LQF09_12540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LQF09_12550	COG0494	nUDIX hydrolase
LQF09_12555	COG1007	ATP synthesis coupled electron transport
LQF09_12570	COG0713	ATP synthesis coupled electron transport
LQF09_12580	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LQF09_12585	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LQF09_12590	COG1034	ATP synthesis coupled electron transport
LQF09_12600	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LQF09_12605	COG0649	NAD binding
LQF09_12610	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LQF09_12615	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LQF09_12620	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LQF09_12635	COG0149	triose-phosphate isomerase activity
LQF09_12640	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LQF09_12645	COG1185	polyribonucleotide nucleotidyltransferase activity
LQF09_12650	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LQF09_12655	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LQF09_12660	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LQF09_12665	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LQF09_12670	COG0195	Participates in both transcription termination and antitermination
LQF09_12670	COG2251	uridine kinase activity
LQF09_12675	COG0779	Required for maturation of 30S ribosomal subunits
LQF09_12680	COG1187	pseudouridine synthase activity
LQF09_12685	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LQF09_12690	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LQF09_12695	COG0180	Tryptophanyl-tRNA synthetase
LQF09_12700	COG1994	Peptidase M50
LQF09_12705	COG0009	L-threonylcarbamoyladenylate synthase
LQF09_12710	COG0613	PHP domain protein
LQF09_12720	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LQF09_12725	COG1278	Cold shock
LQF09_12740	COG3706	GGDEF domain
LQF09_12740	COG4251	negative regulation of phosphorylation
LQF09_12740	COG2203	Gaf domain
LQF09_12740	COG5001	Diguanylate cyclase
LQF09_12745	COG4681	YaeQ
LQF09_12760	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LQF09_12770	COG0302	gtp cyclohydrolase
LQF09_12780	COG0306	phosphate transporter
LQF09_12790	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LQF09_12805	COG0791	NLP P60 protein
LQF09_12810	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LQF09_12815	COG0148	phosphopyruvate hydratase activity
LQF09_12820	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LQF09_12825	COG0504	CTP synthase activity
LQF09_12830	COG2902	Dehydrogenase
LQF09_12855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LQF09_12870	COG0456	acetyltransferase
LQF09_12870	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LQF09_12875	COG1238	metal cluster binding
LQF09_12920	COG0697	spore germination
LQF09_12940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LQF09_12940	COG1199	ATP-dependent helicase activity
LQF09_12950	COG0456	acetyltransferase
LQF09_12955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LQF09_12960	COG1917	Cupin 2, conserved barrel domain protein
LQF09_12965	COG5285	phytanoyl-CoA dioxygenase
LQF09_12990	COG4691	Plasmid stability protein
LQF09_13000	COG0009	L-threonylcarbamoyladenylate synthase
LQF09_13005	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LQF09_13010	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LQF09_13015	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LQF09_13025	COG4566	intracellular signal transduction
LQF09_13040	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LQF09_13045	COG0508	dehydrogenase complex catalyzes the overall conversion of
LQF09_13050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LQF09_13055	COG4771	TonB-dependent receptor
LQF09_13080	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LQF09_13080	COG0047	phosphoribosylformylglycinamidine synthase activity
LQF09_13145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LQF09_13150	COG4569	acetaldehyde dehydrogenase (acetylating) activity
LQF09_13235	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LQF09_13240	COG0509	glycine decarboxylation via glycine cleavage system
LQF09_13245	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LQF09_13245	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LQF09_13260	COG1215	transferase activity, transferring glycosyl groups
LQF09_13265	COG0471	metal ion transport
LQF09_13270	COG0205	6-phosphofructokinase activity
LQF09_13275	COG0563	adenylate kinase activity
LQF09_13280	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LQF09_13285	COG2835	tetraacyldisaccharide 4'-kinase activity
LQF09_13290	COG1663	tetraacyldisaccharide 4'-kinase activity
LQF09_13295	COG0848	biopolymer transport protein
LQF09_13300	COG0811	peptide transport
LQF09_13305	COG1570	exodeoxyribonuclease VII activity
LQF09_13310	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LQF09_13315	COG0564	pseudouridine synthase activity
LQF09_13325	COG0784	Response regulator, receiver
LQF09_13325	COG2198	Histidine kinase
LQF09_13325	COG0643	Histidine kinase
LQF09_13330	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LQF09_13335	COG0745	RESPONSE REGULATOR receiver
LQF09_13340	COG0784	Response regulator, receiver
LQF09_13340	COG0835	chemotaxis
LQF09_13345	COG0784	Response regulator, receiver
LQF09_13345	COG0835	chemotaxis
LQF09_13355	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LQF09_13385	COG4657	Part of a membrane complex involved in electron transport
LQF09_13390	COG2878	Part of a membrane complex involved in electron transport
LQF09_13405	COG4659	FMN binding
LQF09_13410	COG4660	Part of a membrane complex involved in electron transport
LQF09_13415	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LQF09_13435	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LQF09_13465	COG2217	Heavy metal translocating P-type atpase
LQF09_13485	COG2132	Multicopper oxidase
LQF09_13510	COG5654	RES domain protein
LQF09_13520	COG4974	Belongs to the 'phage' integrase family
LQF09_13525	COG0517	IMP dehydrogenase activity
LQF09_13530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LQF09_13535	COG1518	maintenance of DNA repeat elements
LQF09_13565	COG1857	crispr-associated protein
LQF09_13580	COG1203	CRISPR-associated helicase, Cas3
LQF09_13590	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQF09_13595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQF09_13615	COG5002	protein histidine kinase activity
LQF09_13625	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LQF09_13630	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LQF09_13655	COG0326	Molecular chaperone. Has ATPase activity
LQF09_13660	COG0840	transmembrane signaling receptor activity
LQF09_13685	COG0840	transmembrane signaling receptor activity
LQF09_13730	COG3845	ABC transporter
LQF09_13735	COG4603	Belongs to the binding-protein-dependent transport system permease family
LQF09_13740	COG1079	Belongs to the binding-protein-dependent transport system permease family
LQF09_13785	COG4266	Belongs to the allantoicase family
LQF09_13805	COG0604	alcohol dehydrogenase
LQF09_13810	COG1309	transcriptional regulator
LQF09_13815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LQF09_13830	COG0348	domain, Protein
LQF09_13835	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LQF09_13845	COG0842	Transport permease protein
LQF09_13850	COG1131	(ABC) transporter
LQF09_13870	COG2252	PERMEase
LQF09_13885	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LQF09_13895	COG0402	S-adenosylhomocysteine deaminase activity
LQF09_13900	COG0697	spore germination
LQF09_13905	COG1953	Uracil, thiamine, allantoin
LQF09_13925	COG4266	Belongs to the allantoicase family
LQF09_13930	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
LQF09_13935	COG0747	negative chemotaxis
LQF09_13940	COG0601	transmembrane transport
LQF09_13945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LQF09_13950	COG4608	Belongs to the ABC transporter superfamily
LQF09_13970	COG0583	DNA-binding transcription factor activity
LQF09_13975	COG3960	tartronate-semialdehyde synthase activity
LQF09_13980	COG3622	Belongs to the hyi family
LQF09_13985	COG2084	Dehydrogenase
LQF09_14000	COG0469	pyruvate kinase activity
LQF09_14005	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LQF09_14020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LQF09_14025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LQF09_14040	COG3243	poly(R)-hydroxyalkanoic acid synthase
LQF09_14045	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LQF09_14090	COG3278	Belongs to the heme-copper respiratory oxidase family
LQF09_14100	COG2217	Heavy metal translocating P-type atpase
LQF09_14140	COG1346	cytolysis
LQF09_14150	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LQF09_14165	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LQF09_14190	COG0446	pyridine nucleotide-disulphide oxidoreductase
LQF09_14205	COG0756	dUTP diphosphatase activity
LQF09_14210	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LQF09_14215	COG2003	Belongs to the UPF0758 family
LQF09_14220	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LQF09_14225	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LQF09_14230	COG1278	Cold shock
LQF09_14235	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LQF09_14240	COG0542	response to heat
LQF09_14245	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LQF09_14265	COG2205	protein histidine kinase activity
LQF09_14270	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LQF09_14275	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LQF09_14280	COG0697	spore germination
LQF09_14295	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LQF09_14300	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LQF09_14305	COG0739	heme binding
LQF09_14310	COG0316	Belongs to the HesB IscA family
LQF09_14315	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LQF09_14320	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LQF09_14325	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LQF09_14330	COG1765	OsmC-like protein
LQF09_14335	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
LQF09_14345	COG0494	nUDIX hydrolase
LQF09_14350	COG0442	prolyl-tRNA aminoacylation
LQF09_14355	COG0741	lytic transglycosylase activity
LQF09_14365	COG2205	protein histidine kinase activity
LQF09_14375	COG2204	response regulator
LQF09_14385	COG0312	modulator of DNA gyrase
LQF09_14390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LQF09_14400	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LQF09_14425	COG0482	sulfurtransferase activity
LQF09_14480	COG0210	DNA helicase
LQF09_14490	COG0495	leucyl-tRNA aminoacylation
LQF09_14500	COG1466	dna polymerase III delta subunit
LQF09_14505	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LQF09_14510	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LQF09_14515	COG4974	Belongs to the 'phage' integrase family
LQF09_14535	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LQF09_14540	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LQF09_14545	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LQF09_14570	COG2070	2-Nitropropane dioxygenase
LQF09_14590	COG1058	Belongs to the CinA family
LQF09_14590	COG1546	Belongs to the CinA family
LQF09_14600	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LQF09_14610	COG4536	flavin adenine dinucleotide binding
LQF09_14625	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LQF09_14640	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LQF09_14645	COG2204	response regulator
LQF09_14670	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LQF09_14685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LQF09_14710	COG0243	molybdopterin cofactor binding
LQF09_14720	COG2223	nitrite transmembrane transporter activity
LQF09_14730	COG1116	anion transmembrane transporter activity
LQF09_14735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LQF09_14740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LQF09_14745	COG3707	response regulator
LQF09_14750	COG0167	dihydroorotate dehydrogenase activity
LQF09_14755	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LQF09_14765	COG0535	radical SAM domain protein
LQF09_14775	COG0778	Nitroreductase
LQF09_14780	COG2146	nitrite reductase [NAD(P)H] activity
LQF09_14780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LQF09_14790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LQF09_14795	COG0557	exoribonuclease II activity
LQF09_14810	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LQF09_14815	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LQF09_14820	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LQF09_14825	COG0330	HflC and HflK could
LQF09_14830	COG0330	HflC and HflK could
LQF09_14835	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LQF09_14840	COG1923	regulation of RNA biosynthetic process
LQF09_14845	COG1160	GTP binding
LQF09_14850	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LQF09_14860	COG0124	histidyl-tRNA synthetase
LQF09_14865	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LQF09_14870	COG1426	Protein conserved in bacteria
LQF09_14880	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LQF09_14885	COG0105	UTP biosynthetic process
LQF09_14905	COG0037	tRNA processing
LQF09_14910	COG0825	malonyl-CoA metabolic process
LQF09_14915	COG0670	Belongs to the BI1 family
LQF09_14925	COG0583	DNA-binding transcription factor activity
LQF09_14935	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LQF09_14940	COG0343	queuine tRNA-ribosyltransferase activity
LQF09_14945	COG1862	Preprotein translocase
LQF09_14950	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LQF09_14955	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LQF09_14970	COG2967	ApaG domain
LQF09_14980	COG3447	MASE1 domain protein
LQF09_14980	COG5001	Diguanylate cyclase
LQF09_14980	COG5002	protein histidine kinase activity
LQF09_14995	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LQF09_15000	COG0653	protein targeting
LQF09_15015	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LQF09_15020	COG2084	Dehydrogenase
LQF09_15025	COG2084	Dehydrogenase
LQF09_15030	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LQF09_15045	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LQF09_15055	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LQF09_15080	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LQF09_15090	COG0629	single-stranded DNA binding
LQF09_15095	COG2814	Major facilitator Superfamily
LQF09_15105	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LQF09_15110	COG0203	ribosomal protein L17
LQF09_15115	COG0202	RNA polymerase activity
LQF09_15120	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LQF09_15125	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LQF09_15130	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LQF09_15135	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LQF09_15140	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LQF09_15145	COG0201	protein transport
LQF09_15150	COG0200	Binds to the 23S rRNA
LQF09_15155	COG1841	ribosomal large subunit assembly
LQF09_15160	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LQF09_15165	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LQF09_15170	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LQF09_15175	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LQF09_15180	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LQF09_15185	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LQF09_15190	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LQF09_15195	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LQF09_15200	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LQF09_15205	COG0255	Belongs to the universal ribosomal protein uL29 family
LQF09_15210	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LQF09_15215	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LQF09_15220	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LQF09_15225	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LQF09_15230	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LQF09_15235	COG0089	rRNA binding
LQF09_15240	COG0088	Forms part of the polypeptide exit tunnel
LQF09_15245	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LQF09_15250	COG0051	transcription antitermination factor activity, RNA binding
LQF09_15255	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LQF09_15260	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LQF09_15265	COG0049	tRNA binding
LQF09_15270	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LQF09_15275	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LQF09_15280	COG0085	RNA polymerase activity
LQF09_15285	COG0222	ribosome binding
LQF09_15290	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LQF09_15295	COG0081	regulation of translation
LQF09_15300	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LQF09_15310	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LQF09_15320	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LQF09_15340	COG2226	methyltransferase
LQF09_15350	COG2197	response regulator
LQF09_15360	COG4999	Histidine kinase
LQF09_15360	COG2205	protein histidine kinase activity
LQF09_15360	COG3437	response regulator, receiver
LQF09_15360	COG3850	Histidine kinase
LQF09_15370	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LQF09_15405	COG1022	Amp-dependent synthetase and ligase
LQF09_15410	COG5001	Diguanylate cyclase
LQF09_15445	COG1703	isobutyryl-CoA mutase activity
LQF09_15445	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LQF09_15445	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LQF09_15470	COG0840	transmembrane signaling receptor activity
LQF09_15495	COG1125	glycine betaine transport
LQF09_15495	COG0517	IMP dehydrogenase activity
LQF09_15500	COG0737	Belongs to the 5'-nucleotidase family
LQF09_15545	COG0438	transferase activity, transferring glycosyl groups
LQF09_15560	COG0438	transferase activity, transferring glycosyl groups
LQF09_15585	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LQF09_15590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LQF09_15595	COG0489	protein tyrosine kinase activity
LQF09_15595	COG3206	protein involved in exopolysaccharide biosynthesis
LQF09_15620	COG1509	lysine 2,3-aminomutase activity
LQF09_15625	COG4770	biotin carboxylase activity
LQF09_15630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LQF09_15635	COG1703	isobutyryl-CoA mutase activity
LQF09_15640	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LQF09_15640	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LQF09_15645	COG1802	Transcriptional regulator
LQF09_15665	COG1253	flavin adenine dinucleotide binding
LQF09_15670	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LQF09_15675	COG3162	membrane
LQF09_15680	COG1024	Enoyl-CoA hydratase
LQF09_15685	COG1538	Outer membrane efflux protein
LQF09_15695	COG5001	Diguanylate cyclase
LQF09_15710	COG2197	response regulator
LQF09_15715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQF09_15735	COG1136	(ABC) transporter
LQF09_15745	COG0735	belongs to the Fur family
LQF09_15755	COG1121	(ABC) transporter
LQF09_15765	COG0803	Belongs to the bacterial solute-binding protein 9 family
LQF09_15780	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LQF09_15790	COG0129	dihydroxy-acid dehydratase activity
LQF09_15795	COG3132	Protein of unknown function, DUF480
LQF09_15800	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LQF09_15815	COG5001	Diguanylate cyclase
LQF09_15865	COG1858	cytochrome C peroxidase
LQF09_15870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQF09_15875	COG0577	efflux transmembrane transporter activity
LQF09_15875	COG1136	(ABC) transporter
LQF09_15880	COG1538	Outer membrane efflux protein
LQF09_15885	COG4774	siderophore transport
LQF09_15905	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LQF09_15925	COG4206	TonB-dependent receptor
LQF09_15930	COG1429	ligase activity, forming nitrogen-metal bonds
LQF09_15935	COG4771	TonB-dependent receptor
LQF09_15955	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LQF09_15960	COG1918	ferrous iron import across plasma membrane
LQF09_16010	COG1116	anion transmembrane transporter activity
LQF09_16025	COG4771	TonB-dependent receptor
LQF09_16035	COG0784	Response regulator, receiver
LQF09_16035	COG4191	Histidine kinase
LQF09_16040	COG0318	PFAM AMP-dependent synthetase and ligase
LQF09_16045	COG0659	secondary active sulfate transmembrane transporter activity
LQF09_16060	COG2119	membrane
LQF09_16065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQF09_16130	COG3501	Rhs element vgr protein
LQF09_16170	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LQF09_16185	COG1028	Short-chain dehydrogenase reductase Sdr
LQF09_16205	COG0183	Belongs to the thiolase family
LQF09_16210	COG1960	acyl-CoA dehydrogenase activity
LQF09_16215	COG1024	Enoyl-CoA hydratase
LQF09_16220	COG1022	Amp-dependent synthetase and ligase
LQF09_16235	COG1172	Belongs to the binding-protein-dependent transport system permease family
LQF09_16325	COG0723	plastoquinol--plastocyanin reductase activity
LQF09_16355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LQF09_16365	COG0514	ATP-dependent DNA helicase (RecQ)
LQF09_16370	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LQF09_16425	COG0583	DNA-binding transcription factor activity
LQF09_16465	COG4372	Transposase
LQF09_16480	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LQF09_16495	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
LQF09_16500	COG2204	response regulator
LQF09_16520	COG2135	peptidase activity
LQF09_16525	COG0464	growth
LQF09_16535	COG2433	Pfam Transposase IS66
LQF09_16560	COG0517	IMP dehydrogenase activity
LQF09_16565	COG4974	Belongs to the 'phage' integrase family
LQF09_16585	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LQF09_16595	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LQF09_16600	COG0405	Gamma-glutamyltransferase
LQF09_16610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LQF09_16620	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LQF09_16620	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LQF09_16625	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LQF09_16630	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LQF09_16635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LQF09_16645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LQF09_16650	COG2022	thiamine diphosphate biosynthetic process
LQF09_16660	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LQF09_16665	COG2855	membrane
LQF09_16720	COG1414	Transcriptional regulator
LQF09_16725	COG0730	response to heat
LQF09_16745	COG1414	Transcriptional regulator
LQF09_16750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LQF09_16760	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LQF09_16770	COG0067	glutamate synthase
LQF09_16770	COG0069	glutamate synthase activity
LQF09_16770	COG0070	glutamate synthase
LQF09_16775	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LQF09_16780	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LQF09_16785	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LQF09_16820	COG1965	Belongs to the frataxin family
LQF09_16850	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LQF09_16855	COG0284	orotidine-5'-phosphate decarboxylase activity
LQF09_16860	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LQF09_16865	COG3161	chorismate lyase activity
LQF09_16870	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LQF09_16880	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LQF09_16905	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LQF09_16920	COG1805	sodium ion transport
LQF09_16930	COG0183	Belongs to the thiolase family
LQF09_16935	COG1250	3-hydroxyacyl-CoA dehydrogenase
LQF09_16935	COG1024	Enoyl-CoA hydratase
LQF09_16940	COG1607	acyl-coa hydrolase
LQF09_16945	COG1024	Enoyl-CoA hydratase
LQF09_16945	COG1250	3-hydroxyacyl-CoA dehydrogenase
LQF09_16955	COG1960	acyl-CoA dehydrogenase activity
LQF09_16960	COG1309	transcriptional regulator
LQF09_16985	COG5265	(ABC) transporter
LQF09_17000	COG0252	asparaginase activity
LQF09_17005	COG0583	DNA-binding transcription factor activity
LQF09_17020	COG0175	sulfate reduction
LQF09_17030	COG0175	sulfate reduction
LQF09_17035	COG2895	sulfate adenylyltransferase (ATP) activity
LQF09_17045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LQF09_17055	COG0330	HflC and HflK could
LQF09_17065	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LQF09_17070	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LQF09_17080	COG0824	Thioesterase
LQF09_17090	COG0848	biopolymer transport protein
LQF09_17100	COG0823	Involved in the tonB-independent uptake of proteins
LQF09_17115	COG0602	queuosine metabolic process
LQF09_17120	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LQF09_17135	COG1671	Belongs to the UPF0178 family
LQF09_17140	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LQF09_17145	COG0412	Dienelactone hydrolase
LQF09_17160	COG1660	Displays ATPase and GTPase activities
LQF09_17165	COG1115	amino acid carrier protein
LQF09_17185	COG1012	belongs to the aldehyde dehydrogenase family
LQF09_17230	COG1132	(ABC) transporter
LQF09_17235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LQF09_17255	COG0318	PFAM AMP-dependent synthetase and ligase
LQF09_17270	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LQF09_17275	COG1960	acyl-CoA dehydrogenase activity
LQF09_17285	COG1607	acyl-coa hydrolase
LQF09_17330	COG3284	Transcriptional regulator
LQF09_17360	COG2197	response regulator
LQF09_17375	COG1960	acyl-CoA dehydrogenase activity
LQF09_17380	COG0183	Belongs to the thiolase family
LQF09_17385	COG0288	reversible hydration of carbon dioxide
LQF09_17405	COG3243	poly(R)-hydroxyalkanoic acid synthase
LQF09_17415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LQF09_17445	COG0018	arginyl-trna synthetase
LQF09_17450	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LQF09_17460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LQF09_17475	COG1360	Flagellar Motor Protein
LQF09_17480	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LQF09_17485	COG0826	peptidase U32
LQF09_17490	COG0826	peptidase U32
LQF09_17495	COG3154	lipid carrier protein
LQF09_17500	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LQF09_17505	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LQF09_17510	COG1546	Belongs to the CinA family
LQF09_17515	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LQF09_17520	COG2137	regulation of response to DNA damage stimulus
LQF09_17525	COG1137	ATPase activity
LQF09_17530	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LQF09_17535	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LQF09_17545	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LQF09_17555	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LQF09_17560	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LQF09_17580	COG0617	tRNA 3'-terminal CCA addition
LQF09_17585	COG2267	carboxylic ester hydrolase activity
LQF09_17600	COG0037	tRNA processing
LQF09_17630	COG0243	molybdopterin cofactor binding
LQF09_17640	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LQF09_17645	COG0708	Exodeoxyribonuclease III
LQF09_17655	COG4575	ribosome binding
LQF09_17670	COG2233	PERMEase
LQF09_17675	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LQF09_17680	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LQF09_17705	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
LQF09_17725	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LQF09_17730	COG0830	nickel cation binding
LQF09_17735	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
LQF09_17740	COG0804	urea catabolic process
LQF09_17745	COG0832	Belongs to the urease beta subunit family
LQF09_17750	COG0831	urea catabolic process
LQF09_17755	COG0829	nickel cation binding
LQF09_17785	COG1024	Enoyl-CoA hydratase
LQF09_17790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LQF09_17855	COG3609	addiction module antidote protein, CC2985 family
LQF09_17885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LQF09_17905	COG0277	FAD linked oxidase domain protein
LQF09_17910	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LQF09_17930	COG0583	DNA-binding transcription factor activity
LQF09_17940	COG0180	Tryptophanyl-tRNA synthetase
LQF09_17965	COG3876	Protein conserved in bacteria
LQF09_17970	COG0659	secondary active sulfate transmembrane transporter activity
LQF09_17975	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LQF09_17990	COG0583	DNA-binding transcription factor activity
LQF09_17995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LQF09_18020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LQF09_18025	COG4597	amino acid ABC transporter
LQF09_18030	COG0765	amino acid transport
LQF09_18035	COG1126	abc transporter atp-binding protein
LQF09_18050	COG0559	Belongs to the binding-protein-dependent transport system permease family
LQF09_18080	COG2814	Major facilitator Superfamily
LQF09_18085	COG0606	chelatase, subunit chli
LQF09_18100	COG0347	Belongs to the P(II) protein family
LQF09_18105	COG0004	ammonium transporteR
LQF09_18110	COG0347	Belongs to the P(II) protein family
LQF09_18115	COG0004	ammonium transporteR
LQF09_18130	COG1960	acyl-CoA dehydrogenase activity
LQF09_18135	COG0527	aspartate kinase activity
LQF09_18140	COG0788	formyltetrahydrofolate deformylase activity
LQF09_18155	COG0488	(ABC) transporter
LQF09_18170	COG0697	spore germination
LQF09_18190	COG0189	ligase activity
LQF09_18200	COG1522	sequence-specific DNA binding
LQF09_18210	COG0683	leucine binding
LQF09_18245	COG0840	transmembrane signaling receptor activity
LQF09_18265	COG0827	DNA restriction-modification system
LQF09_18265	COG0732	type I restriction modification DNA specificity domain
LQF09_18270	COG2226	methyltransferase
LQF09_18275	COG2267	carboxylic ester hydrolase activity
LQF09_18280	COG0318	PFAM AMP-dependent synthetase and ligase
LQF09_18310	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LQF09_18310	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LQF09_18315	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LQF09_18315	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LQF09_18320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LQF09_18330	COG1944	ATP diphosphatase activity
LQF09_18345	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LQF09_18350	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LQF09_18355	COG1074	ATP-dependent DNA helicase activity
LQF09_18360	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LQF09_18365	COG1832	CoA-binding protein
LQF09_18380	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LQF09_18385	COG4208	sulfate ABC transporter
LQF09_18390	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LQF09_18395	COG0583	DNA-binding transcription factor activity
LQF09_18405	COG0574	Belongs to the PEP-utilizing enzyme family
LQF09_18405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LQF09_18415	COG3243	poly(R)-hydroxyalkanoic acid synthase
LQF09_18465	COG3046	protein related to deoxyribodipyrimidine photolyase
LQF09_18470	COG1739	Uncharacterized protein family UPF0029
LQF09_18475	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LQF09_18485	COG4993	Dehydrogenase
LQF09_18500	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LQF09_18505	COG0022	dehydrogenase e1 component
LQF09_18510	COG0509	glycine decarboxylation via glycine cleavage system
LQF09_18540	COG3284	Transcriptional regulator
LQF09_18555	COG1013	pyruvate-flavodoxin oxidoreductase activity
LQF09_18555	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LQF09_18555	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LQF09_18555	COG0674	pyruvate-flavodoxin oxidoreductase activity
LQF09_18565	COG1160	GTP binding
LQF09_18575	COG2703	oxygen carrier activity
LQF09_18590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQF09_18615	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LQF09_18640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LQF09_18660	COG4804	nuclease activity
LQF09_18695	COG4181	ATPase activity
LQF09_18700	COG1253	flavin adenine dinucleotide binding
LQF09_18705	COG1253	flavin adenine dinucleotide binding
LQF09_18710	COG0628	permease
LQF09_18715	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LQF09_18720	COG0583	DNA-binding transcription factor activity
LQF09_18725	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LQF09_18730	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LQF09_18775	COG0419	ATPase involved in DNA repair
LQF09_18780	COG0420	3'-5' exonuclease activity
LQF09_18790	COG4585	Histidine kinase
LQF09_18810	COG3237	CsbD-like
LQF09_18815	COG0488	(ABC) transporter
LQF09_18830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LQF09_18835	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LQF09_18835	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LQF09_18840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LQF09_18845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LQF09_18855	COG0318	PFAM AMP-dependent synthetase and ligase
LQF09_18875	COG0582	viral genome integration into host DNA
LQF09_18980	COG0583	DNA-binding transcription factor activity
LQF09_19010	COG3300	MHYT domain
LQF09_19010	COG5001	Diguanylate cyclase
LQF09_19025	COG0501	Belongs to the peptidase M48B family
LQF09_19030	COG0517	IMP dehydrogenase activity
LQF09_19030	COG0617	tRNA 3'-terminal CCA addition
LQF09_19030	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LQF09_19060	COG0318	PFAM AMP-dependent synthetase and ligase
LQF09_19070	COG0318	PFAM AMP-dependent synthetase and ligase
LQF09_19075	COG0671	phosphoesterase, PA-phosphatase related
LQF09_19080	COG3328	transposase activity
LQF09_19215	COG0154	amidase activity
LQF09_19230	COG2197	response regulator
LQF09_19245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LQF09_19250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LQF09_19255	COG4235	cytochrome complex assembly
LQF09_19265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LQF09_19275	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LQF09_19290	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LQF09_19295	COG4133	protoheme IX ABC transporter activity
LQF09_19300	COG3005	denitrification pathway
LQF09_19310	COG0348	domain, Protein
LQF09_19315	COG0437	4 iron, 4 sulfur cluster binding
LQF09_19320	COG0243	molybdopterin cofactor binding
LQF09_19330	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
LQF09_19330	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LQF09_19335	COG2197	response regulator
LQF09_19340	COG3850	Histidine kinase
LQF09_19360	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LQF09_19365	COG1758	RNA polymerase activity
LQF09_19370	COG0194	GDP metabolic process
LQF09_19375	COG1561	YicC-like family, N-terminal region
LQF09_19380	COG0515	serine threonine protein kinase
LQF09_19380	COG1357	PFAM Pentapeptide repeats (8 copies)
LQF09_19385	COG0631	protein serine/threonine phosphatase activity
LQF09_19390	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LQF09_19395	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LQF09_19400	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LQF09_19425	COG0569	domain protein
LQF09_19430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LQF09_19435	COG1028	Short-chain dehydrogenase reductase Sdr
LQF09_19440	COG0596	Alpha beta hydrolase
LQF09_19455	COG1881	PFAM PEBP family protein
LQF09_19460	COG0616	signal peptide processing
LQF09_19465	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LQF09_19470	COG2022	thiamine diphosphate biosynthetic process
LQF09_19480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LQF09_19485	COG2813	Specifically methylates the guanine in position
LQF09_19485	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LQF09_19500	COG2814	Major facilitator Superfamily
LQF09_19540	COG1940	carbohydrate kinase activity
LQF09_19545	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LQF09_19550	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LQF09_19555	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LQF09_19565	COG0569	domain protein
LQF09_19570	COG2204	response regulator
LQF09_19575	COG5000	phosphorelay sensor kinase activity
LQF09_19585	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LQF09_19585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LQF09_19590	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LQF09_19595	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LQF09_19605	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LQF09_19610	COG0706	membrane insertase activity
LQF09_19615	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LQF09_19620	COG0594	ribonuclease P activity
LQF09_19625	COG0230	Belongs to the bacterial ribosomal protein bL34 family