TOT_030000779 a40353a48bfcefa577b00adfbd218c27 859 Pfam PF03074 Glutamate-cysteine ligase 497 856 6.1E-94 T 01-11-2018 IPR004308 Glutamate-cysteine ligase catalytic subunit GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255|Reactome: R-HSA-174403|Reactome: R-HSA-5578999 TOT_030000779 a40353a48bfcefa577b00adfbd218c27 859 Gene3D G3DSA:3.30.590.50 648 745 1.6E-17 T 01-11-2018 TOT_030000779 a40353a48bfcefa577b00adfbd218c27 859 Gene3D G3DSA:3.30.590.50 376 585 2.3E-34 T 01-11-2018 TOT_030000779 a40353a48bfcefa577b00adfbd218c27 859 Gene3D G3DSA:3.30.590.50 42 290 6.3E-27 T 01-11-2018 TOT_030000779 a40353a48bfcefa577b00adfbd218c27 859 Gene3D G3DSA:1.10.8.960 822 858 1.0E-6 T 01-11-2018 TOT_030000779 a40353a48bfcefa577b00adfbd218c27 859 SUPERFAMILY SSF55931 42 849 1.47E-27 T 01-11-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TOT_040000814 1306791a8e5d75a0b67b367d4c26516a 1957 Pfam PF04385 Domain of unknown function, DUF529 1560 1633 1.8E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000814 1306791a8e5d75a0b67b367d4c26516a 1957 Pfam PF04385 Domain of unknown function, DUF529 1886 1942 5.4E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_030000131 adb7c97eb95d1e853c015fd766e8873f 946 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 179 246 1.3E-6 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_030000131 adb7c97eb95d1e853c015fd766e8873f 946 SMART SM00360 178 249 1.8E-8 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_030000131 adb7c97eb95d1e853c015fd766e8873f 946 SUPERFAMILY SSF54928 170 259 8.23E-16 T 01-11-2018 IPR035979 RNA-binding domain superfamily GO:0003676 TOT_030000131 adb7c97eb95d1e853c015fd766e8873f 946 Gene3D G3DSA:3.30.70.330 174 260 5.0E-15 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_040000416 7ee3fa8cc9b5b80f6f7a6a515046c3b2 1120 Pfam PF00271 Helicase conserved C-terminal domain 517 616 1.1E-15 T 01-11-2018 IPR001650 Helicase, C-terminal TOT_040000416 7ee3fa8cc9b5b80f6f7a6a515046c3b2 1120 Pfam PF00270 DEAD/DEAH box helicase 305 474 9.1E-17 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TOT_040000416 7ee3fa8cc9b5b80f6f7a6a515046c3b2 1120 Pfam PF09382 RQC domain 694 811 1.8E-16 T 01-11-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 TOT_040000416 7ee3fa8cc9b5b80f6f7a6a515046c3b2 1120 SUPERFAMILY SSF46785 693 805 2.45E-10 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily TOT_040000416 7ee3fa8cc9b5b80f6f7a6a515046c3b2 1120 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 292 745 1.2E-133 T 01-11-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 TOT_040000416 7ee3fa8cc9b5b80f6f7a6a515046c3b2 1120 Gene3D G3DSA:1.10.10.10 690 812 1.2E-10 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TOT_040000416 7ee3fa8cc9b5b80f6f7a6a515046c3b2 1120 SMART SM00487 298 504 7.3E-27 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOT_040000416 7ee3fa8cc9b5b80f6f7a6a515046c3b2 1120 Pfam PF16124 RecQ zinc-binding 630 686 4.9E-9 T 01-11-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain TOT_040000416 7ee3fa8cc9b5b80f6f7a6a515046c3b2 1120 SUPERFAMILY SSF52540 342 636 3.26E-53 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_040000416 7ee3fa8cc9b5b80f6f7a6a515046c3b2 1120 SMART SM00490 536 617 1.5E-24 T 01-11-2018 IPR001650 Helicase, C-terminal TOT_040000416 7ee3fa8cc9b5b80f6f7a6a515046c3b2 1120 Gene3D G3DSA:3.40.50.300 264 495 2.4E-78 T 01-11-2018 TOT_040000416 7ee3fa8cc9b5b80f6f7a6a515046c3b2 1120 Gene3D G3DSA:3.40.50.300 496 689 6.7E-57 T 01-11-2018 TOT_040000416 7ee3fa8cc9b5b80f6f7a6a515046c3b2 1120 SMART SM00956 696 809 1.3E-5 T 01-11-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 TOT_020000426 47ae6355850bf35a3e5e4812ff33ab17 254 Gene3D G3DSA:3.40.50.1580 7 254 6.0E-45 T 01-11-2018 TOT_020000426 47ae6355850bf35a3e5e4812ff33ab17 254 Pfam PF01048 Phosphorylase superfamily 25 246 2.0E-21 T 01-11-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TOT_020000426 47ae6355850bf35a3e5e4812ff33ab17 254 SUPERFAMILY SSF53167 13 250 3.93E-49 T 01-11-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TOT_030000439 4bcb0e33939550e9707c4d8dd7a48e29 667 Gene3D G3DSA:3.10.20.90 2 103 9.4E-19 T 01-11-2018 TOT_030000439 4bcb0e33939550e9707c4d8dd7a48e29 667 PRINTS PR00348 Ubiquitin signature 58 79 4.6E-6 T 01-11-2018 IPR019956 Ubiquitin TOT_030000439 4bcb0e33939550e9707c4d8dd7a48e29 667 PRINTS PR00348 Ubiquitin signature 16 36 4.6E-6 T 01-11-2018 IPR019956 Ubiquitin TOT_030000439 4bcb0e33939550e9707c4d8dd7a48e29 667 PRINTS PR00348 Ubiquitin signature 37 57 4.6E-6 T 01-11-2018 IPR019956 Ubiquitin TOT_030000439 4bcb0e33939550e9707c4d8dd7a48e29 667 Pfam PF00240 Ubiquitin family 8 78 1.1E-17 T 01-11-2018 IPR000626 Ubiquitin domain GO:0005515 TOT_030000439 4bcb0e33939550e9707c4d8dd7a48e29 667 SUPERFAMILY SSF54236 4 87 2.14E-19 T 01-11-2018 IPR029071 Ubiquitin-like domain superfamily TOT_030000439 4bcb0e33939550e9707c4d8dd7a48e29 667 SMART SM00213 6 77 1.4E-14 T 01-11-2018 IPR000626 Ubiquitin domain GO:0005515 TOT_040000657 7495795d9ff1aee94c037fe46658c9cf 1412 Gene3D G3DSA:1.25.40.180 874 1091 4.6E-36 T 01-11-2018 IPR016021 MIF4G-like domain superfamily TOT_040000657 7495795d9ff1aee94c037fe46658c9cf 1412 Gene3D G3DSA:1.25.40.180 615 762 9.6E-21 T 01-11-2018 IPR016021 MIF4G-like domain superfamily TOT_040000657 7495795d9ff1aee94c037fe46658c9cf 1412 SUPERFAMILY SSF48371 932 1090 5.9E-24 T 01-11-2018 IPR016024 Armadillo-type fold TOT_040000657 7495795d9ff1aee94c037fe46658c9cf 1412 SUPERFAMILY SSF48371 617 696 9.06E-18 T 01-11-2018 IPR016024 Armadillo-type fold TOT_040000657 7495795d9ff1aee94c037fe46658c9cf 1412 SMART SM00543 626 1089 7.5E-11 T 01-11-2018 IPR003890 MIF4G-like, type 3 GO:0003723|GO:0005515 TOT_040000657 7495795d9ff1aee94c037fe46658c9cf 1412 Pfam PF02854 MIF4G domain 930 1084 1.3E-11 T 01-11-2018 IPR003890 MIF4G-like, type 3 GO:0003723|GO:0005515 TOT_040000657 7495795d9ff1aee94c037fe46658c9cf 1412 Pfam PF02854 MIF4G domain 627 691 2.6E-10 T 01-11-2018 IPR003890 MIF4G-like, type 3 GO:0003723|GO:0005515 TOT_040000390 dab5200f59b18ed2dd4ffa4a8e8783dd 855 ProSitePatterns PS00842 XPG protein signature 2. 560 574 - T 01-11-2018 IPR019974 XPG conserved site GO:0016788 TOT_040000390 dab5200f59b18ed2dd4ffa4a8e8783dd 855 Gene3D G3DSA:3.40.50.1010 2 132 6.9E-18 T 01-11-2018 TOT_040000390 dab5200f59b18ed2dd4ffa4a8e8783dd 855 SUPERFAMILY SSF88723 2 640 3.64E-50 T 01-11-2018 IPR029060 PIN-like domain superfamily TOT_040000390 dab5200f59b18ed2dd4ffa4a8e8783dd 855 Pfam PF00867 XPG I-region 558 640 4.8E-25 T 01-11-2018 IPR006086 XPG-I domain GO:0004518 TOT_040000390 dab5200f59b18ed2dd4ffa4a8e8783dd 855 SMART SM00279 627 660 1.1E-8 T 01-11-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 TOT_040000390 dab5200f59b18ed2dd4ffa4a8e8783dd 855 ProSitePatterns PS00841 XPG protein signature 1. 67 81 - T 01-11-2018 IPR019974 XPG conserved site GO:0016788 TOT_040000390 dab5200f59b18ed2dd4ffa4a8e8783dd 855 SMART SM00485 1 95 1.5E-16 T 01-11-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 TOT_040000390 dab5200f59b18ed2dd4ffa4a8e8783dd 855 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 69 88 2.0E-29 T 01-11-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TOT_040000390 dab5200f59b18ed2dd4ffa4a8e8783dd 855 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 556 573 2.0E-29 T 01-11-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TOT_040000390 dab5200f59b18ed2dd4ffa4a8e8783dd 855 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 630 645 2.0E-29 T 01-11-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TOT_040000390 dab5200f59b18ed2dd4ffa4a8e8783dd 855 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 24 38 2.0E-29 T 01-11-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TOT_040000390 dab5200f59b18ed2dd4ffa4a8e8783dd 855 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 577 597 2.0E-29 T 01-11-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TOT_040000390 dab5200f59b18ed2dd4ffa4a8e8783dd 855 Gene3D G3DSA:3.40.50.1010 521 773 3.3E-54 T 01-11-2018 TOT_040000390 dab5200f59b18ed2dd4ffa4a8e8783dd 855 Pfam PF00752 XPG N-terminal domain 1 92 9.0E-16 T 01-11-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 TOT_040000390 dab5200f59b18ed2dd4ffa4a8e8783dd 855 SUPERFAMILY SSF47807 625 763 5.38E-22 T 01-11-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily TOT_040000390 dab5200f59b18ed2dd4ffa4a8e8783dd 855 SMART SM00484 557 625 1.4E-25 T 01-11-2018 IPR006086 XPG-I domain GO:0004518 TOT_010001279 beda3b518ac42bb215b944fb9805a885 1536 Pfam PF00689 Cation transporting ATPase, C-terminus 1213 1521 7.1E-32 T 01-11-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 TOT_010001279 beda3b518ac42bb215b944fb9805a885 1536 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 430 444 2.9E-17 T 01-11-2018 TOT_010001279 beda3b518ac42bb215b944fb9805a885 1536 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 259 273 2.9E-17 T 01-11-2018 TOT_010001279 beda3b518ac42bb215b944fb9805a885 1536 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 901 911 2.9E-17 T 01-11-2018 TOT_010001279 beda3b518ac42bb215b944fb9805a885 1536 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 879 890 2.9E-17 T 01-11-2018 TOT_010001279 beda3b518ac42bb215b944fb9805a885 1536 Gene3D G3DSA:3.40.50.1000 862 974 1.1E-13 T 01-11-2018 IPR023214 HAD superfamily TOT_010001279 beda3b518ac42bb215b944fb9805a885 1536 SUPERFAMILY SSF56784 876 1175 3.56E-41 T 01-11-2018 IPR036412 HAD-like superfamily TOT_010001279 beda3b518ac42bb215b944fb9805a885 1536 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 1097 1213 3.0E-33 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TOT_010001279 beda3b518ac42bb215b944fb9805a885 1536 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 180 455 6.3E-37 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TOT_010001279 beda3b518ac42bb215b944fb9805a885 1536 SUPERFAMILY SSF81660 604 721 2.4E-14 T 01-11-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TOT_010001279 beda3b518ac42bb215b944fb9805a885 1536 Pfam PF00702 haloacid dehalogenase-like hydrolase 1097 1141 1.2E-7 T 01-11-2018 TOT_010001279 beda3b518ac42bb215b944fb9805a885 1536 Gene3D G3DSA:1.20.1110.10 310 454 2.3E-28 T 01-11-2018 TOT_010001279 beda3b518ac42bb215b944fb9805a885 1536 Pfam PF00702 haloacid dehalogenase-like hydrolase 862 924 8.7E-7 T 01-11-2018 TOT_010001279 beda3b518ac42bb215b944fb9805a885 1536 Gene3D G3DSA:2.70.150.10 186 299 2.5E-26 T 01-11-2018 TOT_010001279 beda3b518ac42bb215b944fb9805a885 1536 Pfam PF13246 Cation transport ATPase (P-type) 618 717 5.5E-14 T 01-11-2018 TOT_010001279 beda3b518ac42bb215b944fb9805a885 1536 SUPERFAMILY SSF81653 211 318 6.15E-26 T 01-11-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TOT_010001279 beda3b518ac42bb215b944fb9805a885 1536 SMART SM00831 99 174 8.3E-9 T 01-11-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 TOT_010001279 beda3b518ac42bb215b944fb9805a885 1536 Pfam PF00122 E1-E2 ATPase 209 410 5.9E-48 T 01-11-2018 TOT_010001279 beda3b518ac42bb215b944fb9805a885 1536 Pfam PF00690 Cation transporter/ATPase, N-terminus 101 169 3.7E-15 T 01-11-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 TOT_010001279 beda3b518ac42bb215b944fb9805a885 1536 SUPERFAMILY SSF81665 100 1527 3.79E-97 T 01-11-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TOT_010001279 beda3b518ac42bb215b944fb9805a885 1536 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 432 438 - T 01-11-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TOT_040000423 0ae22f5a7af2401d76a37e5a2bd5a9a9 212 Gene3D G3DSA:2.30.30.30 42 123 4.0E-13 T 01-11-2018 IPR014722 Ribosomal protein L2, domain 2 TOT_040000423 0ae22f5a7af2401d76a37e5a2bd5a9a9 212 Pfam PF01159 Ribosomal protein L6e 81 212 1.1E-25 T 01-11-2018 IPR000915 60S ribosomal protein L6E GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_040000423 0ae22f5a7af2401d76a37e5a2bd5a9a9 212 SUPERFAMILY SSF50104 41 102 3.61E-17 T 01-11-2018 IPR008991 Translation protein SH3-like domain superfamily TOT_010000425 d7d8dbf3f2718740c9ee715b1aa5fedd 528 Gene3D G3DSA:2.130.10.10 433 521 3.2E-16 T 01-11-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TOT_010000425 d7d8dbf3f2718740c9ee715b1aa5fedd 528 SUPERFAMILY SSF50978 197 511 1.49E-61 T 01-11-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 TOT_010000425 d7d8dbf3f2718740c9ee715b1aa5fedd 528 Gene3D G3DSA:1.10.720.150 7 81 3.0E-6 T 01-11-2018 IPR036285 PRP4-like superfamily TOT_010000425 d7d8dbf3f2718740c9ee715b1aa5fedd 528 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 457 471 - T 01-11-2018 IPR019775 WD40 repeat, conserved site TOT_010000425 d7d8dbf3f2718740c9ee715b1aa5fedd 528 SUPERFAMILY SSF158230 16 72 4.58E-11 T 01-11-2018 IPR036285 PRP4-like superfamily TOT_010000425 d7d8dbf3f2718740c9ee715b1aa5fedd 528 Gene3D G3DSA:2.130.10.10 190 263 7.6E-6 T 01-11-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TOT_010000425 d7d8dbf3f2718740c9ee715b1aa5fedd 528 SMART SM00500 36 87 3.3E-8 T 01-11-2018 IPR014906 Pre-mRNA processing factor 4 (PRP4)-like TOT_010000425 d7d8dbf3f2718740c9ee715b1aa5fedd 528 Gene3D G3DSA:2.130.10.10 268 432 5.9E-36 T 01-11-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TOT_010000425 d7d8dbf3f2718740c9ee715b1aa5fedd 528 Pfam PF08799 pre-mRNA processing factor 4 (PRP4) like 41 69 5.1E-10 T 01-11-2018 IPR014906 Pre-mRNA processing factor 4 (PRP4)-like TOT_010000425 d7d8dbf3f2718740c9ee715b1aa5fedd 528 SMART SM00320 236 293 4.3 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_010000425 d7d8dbf3f2718740c9ee715b1aa5fedd 528 SMART SM00320 387 427 2.7E-5 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_010000425 d7d8dbf3f2718740c9ee715b1aa5fedd 528 SMART SM00320 190 231 0.71 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_010000425 d7d8dbf3f2718740c9ee715b1aa5fedd 528 SMART SM00320 345 384 2.1E-4 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_010000425 d7d8dbf3f2718740c9ee715b1aa5fedd 528 SMART SM00320 473 512 0.032 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_010000425 d7d8dbf3f2718740c9ee715b1aa5fedd 528 SMART SM00320 303 342 1.4E-4 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_010000425 d7d8dbf3f2718740c9ee715b1aa5fedd 528 SMART SM00320 430 470 3.9E-5 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_010000425 d7d8dbf3f2718740c9ee715b1aa5fedd 528 Pfam PF00400 WD domain, G-beta repeat 307 342 0.0032 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_010000425 d7d8dbf3f2718740c9ee715b1aa5fedd 528 Pfam PF00400 WD domain, G-beta repeat 433 470 0.01 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_010000425 d7d8dbf3f2718740c9ee715b1aa5fedd 528 Pfam PF00400 WD domain, G-beta repeat 350 383 0.087 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_010000425 d7d8dbf3f2718740c9ee715b1aa5fedd 528 Pfam PF00400 WD domain, G-beta repeat 396 427 0.042 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_020000403 5f554c38e0dea14a640eef2741ba7b02 685 Gene3D G3DSA:2.130.10.10 648 685 6.1E-8 T 01-11-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TOT_020000403 5f554c38e0dea14a640eef2741ba7b02 685 SMART SM00320 645 685 1.1E-7 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_020000403 5f554c38e0dea14a640eef2741ba7b02 685 SMART SM00320 512 551 3.9E-4 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_020000403 5f554c38e0dea14a640eef2741ba7b02 685 SMART SM00320 601 642 3.0 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_020000403 5f554c38e0dea14a640eef2741ba7b02 685 SMART SM00320 384 424 1.3E-7 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_020000403 5f554c38e0dea14a640eef2741ba7b02 685 SMART SM00320 470 509 110.0 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_020000403 5f554c38e0dea14a640eef2741ba7b02 685 SMART SM00320 428 467 7.6E-8 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_020000403 5f554c38e0dea14a640eef2741ba7b02 685 Pfam PF00400 WD domain, G-beta repeat 647 684 3.6E-6 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_020000403 5f554c38e0dea14a640eef2741ba7b02 685 Pfam PF00400 WD domain, G-beta repeat 386 424 9.7E-4 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_020000403 5f554c38e0dea14a640eef2741ba7b02 685 Pfam PF00400 WD domain, G-beta repeat 429 467 6.6E-4 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_020000403 5f554c38e0dea14a640eef2741ba7b02 685 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 411 425 - T 01-11-2018 IPR019775 WD40 repeat, conserved site TOT_020000403 5f554c38e0dea14a640eef2741ba7b02 685 SUPERFAMILY SSF50978 382 684 7.33E-65 T 01-11-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 TOT_020000403 5f554c38e0dea14a640eef2741ba7b02 685 Gene3D G3DSA:2.130.10.10 367 647 9.6E-77 T 01-11-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TOT_020000357 a789e9040eb2be517e6ecb2b0be52f82 170 Gene3D G3DSA:1.10.150.250 88 170 1.3E-10 T 01-11-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily TOT_020000357 a789e9040eb2be517e6ecb2b0be52f82 170 Pfam PF03937 Flavinator of succinate dehydrogenase 93 149 8.9E-10 T 01-11-2018 IPR005631 Flavinator of succinate dehydrogenase TOT_020000357 a789e9040eb2be517e6ecb2b0be52f82 170 SUPERFAMILY SSF109910 87 151 4.58E-11 T 01-11-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily TOT_040000599 66f15139331abd55267fb086fc0d2f65 481 Pfam PF01529 DHHC palmitoyltransferase 157 290 4.9E-35 T 01-11-2018 IPR001594 Palmitoyltransferase, DHHC domain TOT_030000780 d7a8cd5f603483a2c2b80d3090e570bc 440 Pfam PF12656 G-patch domain 245 295 1.6E-14 T 01-11-2018 IPR026822 Spp2/MOS2, G-patch domain Reactome: R-HSA-72163 TOT_010000468 f740146f6eea8bbd3bfaa34023c65203 308 Pfam PF04385 Domain of unknown function, DUF529 40 104 2.5E-8 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_030000774 276d623b5f9c7b4e2b9f38525a689576 218 Pfam PF01111 Cyclin-dependent kinase regulatory subunit 144 217 1.1E-18 T 01-11-2018 IPR000789 Cyclin-dependent kinase, regulatory subunit GO:0016538 TOT_030000774 276d623b5f9c7b4e2b9f38525a689576 218 Gene3D G3DSA:3.30.170.10 140 218 3.3E-22 T 01-11-2018 IPR036858 Cyclin-dependent kinase, regulatory subunit superfamily GO:0016538 TOT_030000774 276d623b5f9c7b4e2b9f38525a689576 218 SUPERFAMILY SSF55637 123 217 3.79E-27 T 01-11-2018 IPR036858 Cyclin-dependent kinase, regulatory subunit superfamily GO:0016538 TOT_030000774 276d623b5f9c7b4e2b9f38525a689576 218 SMART SM01084 143 218 8.5E-11 T 01-11-2018 IPR000789 Cyclin-dependent kinase, regulatory subunit GO:0016538 TOT_020000552 a90b18cd55985f5f4189938b3116d3a9 267 Pfam PF00227 Proteasome subunit 39 109 6.7E-17 T 01-11-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TOT_020000552 a90b18cd55985f5f4189938b3116d3a9 267 Pfam PF00227 Proteasome subunit 136 249 1.0E-19 T 01-11-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TOT_020000552 a90b18cd55985f5f4189938b3116d3a9 267 Gene3D G3DSA:3.60.20.10 34 123 1.3E-22 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TOT_020000552 a90b18cd55985f5f4189938b3116d3a9 267 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 45 92 - T 01-11-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TOT_020000552 a90b18cd55985f5f4189938b3116d3a9 267 SUPERFAMILY SSF56235 23 257 3.29E-48 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TOT_020000552 a90b18cd55985f5f4189938b3116d3a9 267 Gene3D G3DSA:3.60.20.10 124 266 3.3E-31 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TOT_020000720 ed1b989a8b4358c148f9ff26fb1e4199 1489 Pfam PF00664 ABC transporter transmembrane region 822 1093 9.2E-7 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TOT_020000720 ed1b989a8b4358c148f9ff26fb1e4199 1489 SUPERFAMILY SSF90123 814 1127 2.62E-23 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000720 ed1b989a8b4358c148f9ff26fb1e4199 1489 Pfam PF00005 ABC transporter 512 639 9.7E-11 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000720 ed1b989a8b4358c148f9ff26fb1e4199 1489 Gene3D G3DSA:3.40.50.300 462 709 2.2E-32 T 01-11-2018 TOT_020000720 ed1b989a8b4358c148f9ff26fb1e4199 1489 Gene3D G3DSA:3.40.50.300 1201 1484 7.4E-44 T 01-11-2018 TOT_020000720 ed1b989a8b4358c148f9ff26fb1e4199 1489 Pfam PF00005 ABC transporter 1230 1406 2.4E-18 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000720 ed1b989a8b4358c148f9ff26fb1e4199 1489 SUPERFAMILY SSF52540 505 698 1.41E-20 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000720 ed1b989a8b4358c148f9ff26fb1e4199 1489 SUPERFAMILY SSF52540 1219 1475 2.38E-26 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000720 ed1b989a8b4358c148f9ff26fb1e4199 1489 Gene3D G3DSA:1.20.1560.10 805 1132 5.3E-13 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000720 ed1b989a8b4358c148f9ff26fb1e4199 1489 SMART SM00382 1238 1407 0.18 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000720 ed1b989a8b4358c148f9ff26fb1e4199 1489 SMART SM00382 521 721 0.99 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000720 ed1b989a8b4358c148f9ff26fb1e4199 1489 SUPERFAMILY SSF90123 102 207 6.15E-7 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_030000511 cb25dc83878fa9539293005cd812378c 445 SMART SM00668 178 235 4.9E-7 T 01-11-2018 IPR006595 CTLH, C-terminal LisH motif TOT_030000511 cb25dc83878fa9539293005cd812378c 445 Pfam PF10607 CTLH/CRA C-terminal to LisH motif domain 180 348 5.3E-23 T 01-11-2018 IPR024964 CTLH/CRA C-terminal to LisH motif domain TOT_020000261 025f573718eaff387e9e82eb5982a61c 226 SMART SM00360 67 140 9.4E-21 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_020000261 025f573718eaff387e9e82eb5982a61c 226 Gene3D G3DSA:3.30.70.330 43 160 9.2E-22 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_020000261 025f573718eaff387e9e82eb5982a61c 226 SUPERFAMILY SSF54928 43 146 1.61E-24 T 01-11-2018 IPR035979 RNA-binding domain superfamily GO:0003676 TOT_020000261 025f573718eaff387e9e82eb5982a61c 226 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 68 138 5.8E-17 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_040000255 f92b615b90d15ee320ea64c99cdc0ae4 512 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 202 214 - T 01-11-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TOT_040000255 f92b615b90d15ee320ea64c99cdc0ae4 512 SMART SM00220 92 362 3.8E-43 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOT_040000255 f92b615b90d15ee320ea64c99cdc0ae4 512 SUPERFAMILY SSF56112 99 371 3.37E-55 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily TOT_040000255 f92b615b90d15ee320ea64c99cdc0ae4 512 Gene3D G3DSA:3.30.200.20 95 168 5.5E-6 T 01-11-2018 TOT_040000255 f92b615b90d15ee320ea64c99cdc0ae4 512 Pfam PF00069 Protein kinase domain 99 362 2.4E-45 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOT_040000255 f92b615b90d15ee320ea64c99cdc0ae4 512 Gene3D G3DSA:1.10.510.10 169 390 2.2E-46 T 01-11-2018 TOT_010000326 19bcea45f37d2090dce7dccb7fab6230 620 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 281 293 - T 01-11-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TOT_010000326 19bcea45f37d2090dce7dccb7fab6230 620 SUPERFAMILY SSF56112 152 569 6.3E-80 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily TOT_010000326 19bcea45f37d2090dce7dccb7fab6230 620 SMART SM00220 159 564 8.1E-79 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOT_010000326 19bcea45f37d2090dce7dccb7fab6230 620 Gene3D G3DSA:3.30.200.20 569 620 2.1E-5 T 01-11-2018 TOT_010000326 19bcea45f37d2090dce7dccb7fab6230 620 Pfam PF00069 Protein kinase domain 159 316 1.8E-37 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOT_010000326 19bcea45f37d2090dce7dccb7fab6230 620 Pfam PF00069 Protein kinase domain 407 446 6.6E-11 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOT_010000326 19bcea45f37d2090dce7dccb7fab6230 620 Gene3D G3DSA:3.30.200.20 134 243 2.4E-31 T 01-11-2018 TOT_010000326 19bcea45f37d2090dce7dccb7fab6230 620 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 165 188 - T 01-11-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TOT_010000326 19bcea45f37d2090dce7dccb7fab6230 620 ProSitePatterns PS01351 MAP kinase signature. 194 297 - T 01-11-2018 IPR003527 Mitogen-activated protein (MAP) kinase, conserved site GO:0004707|GO:0005524|GO:0006468 KEGG: 04150+2.7.11.24 TOT_020000010 950e892a86f8ed1b19469ed7dd32ad27 1191 Pfam PF04385 Domain of unknown function, DUF529 1001 1071 9.8E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000010 950e892a86f8ed1b19469ed7dd32ad27 1191 Pfam PF04385 Domain of unknown function, DUF529 540 610 9.8E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000894 880d4f493eaefcb85d50894a08805950 656 Gene3D G3DSA:1.10.1900.10 589 656 3.9E-25 T 01-11-2018 TOT_010000894 880d4f493eaefcb85d50894a08805950 656 Gene3D G3DSA:3.30.70.330 200 274 1.8E-15 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_010000894 880d4f493eaefcb85d50894a08805950 656 Pfam PF00658 Poly-adenylate binding protein, unique domain 596 652 4.7E-25 T 01-11-2018 IPR002004 Polyadenylate-binding protein/Hyperplastic disc protein GO:0003723 TOT_010000894 880d4f493eaefcb85d50894a08805950 656 Gene3D G3DSA:3.30.70.330 16 115 4.0E-23 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_010000894 880d4f493eaefcb85d50894a08805950 656 Gene3D G3DSA:3.30.70.330 275 398 3.7E-25 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_010000894 880d4f493eaefcb85d50894a08805950 656 SMART SM00360 28 101 2.7E-22 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_010000894 880d4f493eaefcb85d50894a08805950 656 SMART SM00360 116 188 1.8E-23 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_010000894 880d4f493eaefcb85d50894a08805950 656 SMART SM00360 204 276 1.7E-12 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_010000894 880d4f493eaefcb85d50894a08805950 656 SMART SM00360 307 379 7.8E-23 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_010000894 880d4f493eaefcb85d50894a08805950 656 SUPERFAMILY SSF54928 26 195 6.39E-48 T 01-11-2018 IPR035979 RNA-binding domain superfamily GO:0003676 TOT_010000894 880d4f493eaefcb85d50894a08805950 656 TIGRFAM TIGR01628 PABP-1234: polyadenylate binding protein, human types 1, 2, 3, 4 family 27 653 5.6E-203 T 01-11-2018 IPR006515 Polyadenylate binding protein, human types 1, 2, 3, 4 GO:0003723 TOT_010000894 880d4f493eaefcb85d50894a08805950 656 SUPERFAMILY SSF54928 199 286 2.28E-15 T 01-11-2018 IPR035979 RNA-binding domain superfamily GO:0003676 TOT_010000894 880d4f493eaefcb85d50894a08805950 656 SMART SM00517 592 655 2.8E-28 T 01-11-2018 IPR002004 Polyadenylate-binding protein/Hyperplastic disc protein GO:0003723 TOT_010000894 880d4f493eaefcb85d50894a08805950 656 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 308 376 2.8E-16 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_010000894 880d4f493eaefcb85d50894a08805950 656 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 29 97 1.7E-18 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_010000894 880d4f493eaefcb85d50894a08805950 656 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 205 267 2.6E-11 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_010000894 880d4f493eaefcb85d50894a08805950 656 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 117 185 1.7E-20 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_010000894 880d4f493eaefcb85d50894a08805950 656 SUPERFAMILY SSF54928 305 397 1.29E-25 T 01-11-2018 IPR035979 RNA-binding domain superfamily GO:0003676 TOT_010000894 880d4f493eaefcb85d50894a08805950 656 Gene3D G3DSA:3.30.70.330 116 199 1.6E-22 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_010000894 880d4f493eaefcb85d50894a08805950 656 SUPERFAMILY SSF63570 534 655 7.98E-30 T 01-11-2018 IPR036053 PABC (PABP) domain GO:0003723 TOT_040000897 6dc7d3a1e0202752c01313406a15629f 463 Pfam PF00375 Sodium:dicarboxylate symporter family 61 444 7.3E-17 T 01-11-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 TOT_040000897 6dc7d3a1e0202752c01313406a15629f 463 Gene3D G3DSA:1.10.3860.10 21 462 8.8E-21 T 01-11-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 TOT_040000897 6dc7d3a1e0202752c01313406a15629f 463 SUPERFAMILY SSF118215 42 445 7.72E-20 T 01-11-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 TOT_010001361 a8d0bd5b6d6770b1e377e69593ba1439 290 SUPERFAMILY SSF48371 52 263 5.13E-7 T 01-11-2018 IPR016024 Armadillo-type fold TOT_010001361 a8d0bd5b6d6770b1e377e69593ba1439 290 Gene3D G3DSA:1.25.10.10 46 288 1.2E-14 T 01-11-2018 IPR011989 Armadillo-like helical TOT_040000108 f5ddc9158c0bc420e4e6c3936254d921 751 Gene3D G3DSA:4.10.1060.10 295 331 1.6E-9 T 01-11-2018 TOT_040000108 f5ddc9158c0bc420e4e6c3936254d921 751 SUPERFAMILY SSF90209 299 326 8.83E-6 T 01-11-2018 IPR036443 Zinc finger, RanBP2-type superfamily TOT_040000108 f5ddc9158c0bc420e4e6c3936254d921 751 ProSitePatterns PS01358 Zinc finger RanBP2-type signature. 300 319 - T 01-11-2018 IPR001876 Zinc finger, RanBP2-type TOT_040000108 f5ddc9158c0bc420e4e6c3936254d921 751 Pfam PF00641 Zn-finger in Ran binding protein and others 299 325 4.7E-7 T 01-11-2018 IPR001876 Zinc finger, RanBP2-type TOT_040000108 f5ddc9158c0bc420e4e6c3936254d921 751 SMART SM00547 298 322 3.0E-7 T 01-11-2018 IPR001876 Zinc finger, RanBP2-type TOT_010001329 af2c3fc540023b5415134ac8d034ba1b 1377 SUPERFAMILY SSF56672 810 1019 5.34E-83 T 01-11-2018 TOT_010001329 af2c3fc540023b5415134ac8d034ba1b 1377 ProSitePatterns PS00489 Bacteriophage-type RNA polymerase family active site signature 2. 1146 1160 - T 01-11-2018 IPR002092 DNA-directed RNA polymerase, phage-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-163282|Reactome: R-HSA-2151201 TOT_010001329 af2c3fc540023b5415134ac8d034ba1b 1377 Pfam PF00940 DNA-dependent RNA polymerase 1130 1377 9.3E-72 T 01-11-2018 IPR002092 DNA-directed RNA polymerase, phage-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-163282|Reactome: R-HSA-2151201 TOT_010001329 af2c3fc540023b5415134ac8d034ba1b 1377 Pfam PF00940 DNA-dependent RNA polymerase 876 1018 1.3E-52 T 01-11-2018 IPR002092 DNA-directed RNA polymerase, phage-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-163282|Reactome: R-HSA-2151201 TOT_010001329 af2c3fc540023b5415134ac8d034ba1b 1377 Pfam PF14700 DNA-directed RNA polymerase N-terminal 600 674 5.4E-9 T 01-11-2018 IPR029262 DNA-directed RNA polymerase, N-terminal KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-163282|Reactome: R-HSA-2151201 TOT_010001329 af2c3fc540023b5415134ac8d034ba1b 1377 Pfam PF14700 DNA-directed RNA polymerase N-terminal 259 496 3.0E-8 T 01-11-2018 IPR029262 DNA-directed RNA polymerase, N-terminal KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-163282|Reactome: R-HSA-2151201 TOT_010001329 af2c3fc540023b5415134ac8d034ba1b 1377 Gene3D G3DSA:1.10.150.20 1100 1285 3.4E-40 T 01-11-2018 TOT_010001329 af2c3fc540023b5415134ac8d034ba1b 1377 ProSitePatterns PS00900 Bacteriophage-type RNA polymerase family active site signature 1. 964 975 - T 01-11-2018 IPR002092 DNA-directed RNA polymerase, phage-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-163282|Reactome: R-HSA-2151201 TOT_010001329 af2c3fc540023b5415134ac8d034ba1b 1377 Gene3D G3DSA:1.10.287.280 876 955 1.5E-24 T 01-11-2018 TOT_010001329 af2c3fc540023b5415134ac8d034ba1b 1377 SUPERFAMILY SSF56672 251 717 5.78E-28 T 01-11-2018 TOT_010001329 af2c3fc540023b5415134ac8d034ba1b 1377 SUPERFAMILY SSF56672 1126 1377 2.98E-80 T 01-11-2018 TOT_010001329 af2c3fc540023b5415134ac8d034ba1b 1377 SMART SM01311 258 693 4.1E-5 T 01-11-2018 IPR029262 DNA-directed RNA polymerase, N-terminal KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-163282|Reactome: R-HSA-2151201 TOT_010001241 abdf950d885a31522018f176dc4d3463 252 Pfam PF00466 Ribosomal protein L10 57 152 5.1E-12 T 01-11-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 TOT_010001241 abdf950d885a31522018f176dc4d3463 252 SUPERFAMILY SSF160369 58 226 8.11E-18 T 01-11-2018 TOT_010001241 abdf950d885a31522018f176dc4d3463 252 Gene3D G3DSA:3.30.70.1730 56 197 2.2E-22 T 01-11-2018 TOT_030000580 679e2f40e09be963c9b1611b40cabc63 1069 SUPERFAMILY SSF55637 967 1068 1.57E-23 T 01-11-2018 IPR036858 Cyclin-dependent kinase, regulatory subunit superfamily GO:0016538 TOT_030000580 679e2f40e09be963c9b1611b40cabc63 1069 SMART SM01084 985 1069 5.2E-10 T 01-11-2018 IPR000789 Cyclin-dependent kinase, regulatory subunit GO:0016538 TOT_030000580 679e2f40e09be963c9b1611b40cabc63 1069 Gene3D G3DSA:3.30.170.10 982 1069 3.5E-15 T 01-11-2018 IPR036858 Cyclin-dependent kinase, regulatory subunit superfamily GO:0016538 TOT_030000580 679e2f40e09be963c9b1611b40cabc63 1069 Pfam PF01111 Cyclin-dependent kinase regulatory subunit 986 1067 1.8E-17 T 01-11-2018 IPR000789 Cyclin-dependent kinase, regulatory subunit GO:0016538 TOT_020000985 33763a383c00f36252c31282bed1374d 1522 Gene3D G3DSA:3.40.50.300 502 762 1.1E-35 T 01-11-2018 TOT_020000985 33763a383c00f36252c31282bed1374d 1522 Pfam PF00005 ABC transporter 532 659 3.8E-13 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000985 33763a383c00f36252c31282bed1374d 1522 Gene3D G3DSA:3.40.50.300 1222 1516 1.7E-42 T 01-11-2018 TOT_020000985 33763a383c00f36252c31282bed1374d 1522 SUPERFAMILY SSF90123 122 465 2.06E-6 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000985 33763a383c00f36252c31282bed1374d 1522 SUPERFAMILY SSF52540 525 717 3.22E-24 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000985 33763a383c00f36252c31282bed1374d 1522 SUPERFAMILY SSF90123 834 1150 1.57E-24 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000985 33763a383c00f36252c31282bed1374d 1522 Pfam PF00664 ABC transporter transmembrane region 844 1107 1.1E-10 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TOT_020000985 33763a383c00f36252c31282bed1374d 1522 Pfam PF00005 ABC transporter 1253 1439 7.3E-18 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000985 33763a383c00f36252c31282bed1374d 1522 ProSitePatterns PS00211 ABC transporters family signature. 644 658 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_020000985 33763a383c00f36252c31282bed1374d 1522 Gene3D G3DSA:1.20.1560.10 814 1155 1.8E-14 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000985 33763a383c00f36252c31282bed1374d 1522 SMART SM00382 541 743 0.57 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000985 33763a383c00f36252c31282bed1374d 1522 SMART SM00382 1262 1440 0.0012 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000985 33763a383c00f36252c31282bed1374d 1522 SUPERFAMILY SSF52540 1196 1508 1.09E-24 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010000745 f7ad3dfa3afc11da32aa19d850934ea8 383 PRINTS PR00190 Actin signature 58 80 9.1E-18 T 01-11-2018 IPR004000 Actin family TOT_010000745 f7ad3dfa3afc11da32aa19d850934ea8 383 PRINTS PR00190 Actin signature 25 34 9.1E-18 T 01-11-2018 IPR004000 Actin family TOT_010000745 f7ad3dfa3afc11da32aa19d850934ea8 383 PRINTS PR00190 Actin signature 228 244 9.1E-18 T 01-11-2018 IPR004000 Actin family TOT_010000745 f7ad3dfa3afc11da32aa19d850934ea8 383 PRINTS PR00190 Actin signature 111 124 9.1E-18 T 01-11-2018 IPR004000 Actin family TOT_010000745 f7ad3dfa3afc11da32aa19d850934ea8 383 PRINTS PR00190 Actin signature 136 155 9.1E-18 T 01-11-2018 IPR004000 Actin family TOT_010000745 f7ad3dfa3afc11da32aa19d850934ea8 383 SUPERFAMILY SSF53067 3 149 4.53E-35 T 01-11-2018 TOT_010000745 f7ad3dfa3afc11da32aa19d850934ea8 383 SUPERFAMILY SSF53067 142 379 4.49E-63 T 01-11-2018 TOT_010000745 f7ad3dfa3afc11da32aa19d850934ea8 383 Pfam PF00022 Actin 3 379 8.8E-82 T 01-11-2018 IPR004000 Actin family TOT_010000745 f7ad3dfa3afc11da32aa19d850934ea8 383 Gene3D G3DSA:3.90.640.10 176 272 1.2E-113 T 01-11-2018 TOT_010000745 f7ad3dfa3afc11da32aa19d850934ea8 383 Gene3D G3DSA:3.30.420.40 7 375 1.2E-113 T 01-11-2018 TOT_010000745 f7ad3dfa3afc11da32aa19d850934ea8 383 SMART SM00268 4 380 8.8E-104 T 01-11-2018 IPR004000 Actin family TOT_010000745 f7ad3dfa3afc11da32aa19d850934ea8 383 Gene3D G3DSA:3.30.420.40 134 340 1.2E-113 T 01-11-2018 TOT_020000973 a82bad14e7fc600f718971c31d613a6e 763 SUPERFAMILY SSF56784 283 446 9.71E-26 T 01-11-2018 IPR036412 HAD-like superfamily TOT_020000973 a82bad14e7fc600f718971c31d613a6e 763 SUPERFAMILY SSF52113 547 648 6.35E-7 T 01-11-2018 IPR036420 BRCT domain superfamily TOT_020000973 a82bad14e7fc600f718971c31d613a6e 763 SMART SM00577 288 449 8.8E-17 T 01-11-2018 IPR004274 FCP1 homology domain TOT_020000973 a82bad14e7fc600f718971c31d613a6e 763 Pfam PF03031 NLI interacting factor-like phosphatase 291 442 3.6E-22 T 01-11-2018 IPR004274 FCP1 homology domain TOT_020000973 a82bad14e7fc600f718971c31d613a6e 763 Gene3D G3DSA:3.40.50.10190 545 650 1.2E-7 T 01-11-2018 IPR036420 BRCT domain superfamily TOT_020000441 8859bc04f1733996203519839c7d73a1 325 Pfam PF00153 Mitochondrial carrier protein 18 107 3.1E-15 T 01-11-2018 IPR018108 Mitochondrial substrate/solute carrier TOT_020000441 8859bc04f1733996203519839c7d73a1 325 Pfam PF00153 Mitochondrial carrier protein 113 209 3.5E-18 T 01-11-2018 IPR018108 Mitochondrial substrate/solute carrier TOT_020000441 8859bc04f1733996203519839c7d73a1 325 Pfam PF00153 Mitochondrial carrier protein 214 302 3.4E-15 T 01-11-2018 IPR018108 Mitochondrial substrate/solute carrier TOT_020000441 8859bc04f1733996203519839c7d73a1 325 PRINTS PR00926 Mitochondrial carrier protein signature 35 49 6.0E-5 T 01-11-2018 IPR002067 Mitochondrial carrier protein GO:0022857|GO:0055085 TOT_020000441 8859bc04f1733996203519839c7d73a1 325 PRINTS PR00926 Mitochondrial carrier protein signature 129 147 6.0E-5 T 01-11-2018 IPR002067 Mitochondrial carrier protein GO:0022857|GO:0055085 TOT_020000441 8859bc04f1733996203519839c7d73a1 325 PRINTS PR00926 Mitochondrial carrier protein signature 22 35 6.0E-5 T 01-11-2018 IPR002067 Mitochondrial carrier protein GO:0022857|GO:0055085 TOT_020000441 8859bc04f1733996203519839c7d73a1 325 PRINTS PR00926 Mitochondrial carrier protein signature 222 244 6.0E-5 T 01-11-2018 IPR002067 Mitochondrial carrier protein GO:0022857|GO:0055085 TOT_020000441 8859bc04f1733996203519839c7d73a1 325 SUPERFAMILY SSF103506 15 296 4.05E-66 T 01-11-2018 IPR023395 Mitochondrial carrier domain superfamily TOT_020000441 8859bc04f1733996203519839c7d73a1 325 Gene3D G3DSA:1.50.40.10 20 309 1.4E-65 T 01-11-2018 IPR023395 Mitochondrial carrier domain superfamily TOT_020000293 b5f6bca016e873c1a5a02e5a657d3352 174 SUPERFAMILY SSF64356 19 173 8.61E-31 T 01-11-2018 IPR011012 Longin-like domain superfamily TOT_020000293 b5f6bca016e873c1a5a02e5a657d3352 174 Pfam PF04628 Sedlin, N-terminal conserved region 25 171 1.2E-36 T 01-11-2018 IPR006722 Trafficking protein particle complex subunit 2 GO:0005622|GO:0006888 TOT_020000293 b5f6bca016e873c1a5a02e5a657d3352 174 Gene3D G3DSA:3.30.450.70 17 174 2.3E-35 T 01-11-2018 TOT_020000108 9ffbbe5e0b3a078b97a571d2ca83ca20 270 Gene3D G3DSA:4.10.1000.10 70 135 1.7E-5 T 01-11-2018 TOT_020000108 9ffbbe5e0b3a078b97a571d2ca83ca20 270 SMART SM00356 100 125 7.3 T 01-11-2018 IPR000571 Zinc finger, CCCH-type GO:0046872 TOT_020000108 9ffbbe5e0b3a078b97a571d2ca83ca20 270 SMART SM00356 71 91 8.0 T 01-11-2018 IPR000571 Zinc finger, CCCH-type GO:0046872 TOT_020000108 9ffbbe5e0b3a078b97a571d2ca83ca20 270 SMART SM00356 15 40 2.0 T 01-11-2018 IPR000571 Zinc finger, CCCH-type GO:0046872 TOT_040000821 8af096f79a588555152b49656537f1f7 1156 SMART SM00249 556 602 7.5E-11 T 01-11-2018 IPR001965 Zinc finger, PHD-type TOT_040000821 8af096f79a588555152b49656537f1f7 1156 SUPERFAMILY SSF57903 552 604 6.87E-16 T 01-11-2018 IPR011011 Zinc finger, FYVE/PHD-type TOT_040000821 8af096f79a588555152b49656537f1f7 1156 SMART SM00184 395 438 8.4E-6 T 01-11-2018 IPR001841 Zinc finger, RING-type TOT_040000821 8af096f79a588555152b49656537f1f7 1156 SMART SM00184 557 601 1.1 T 01-11-2018 IPR001841 Zinc finger, RING-type TOT_040000821 8af096f79a588555152b49656537f1f7 1156 ProSitePatterns PS01359 Zinc finger PHD-type signature. 557 601 - T 01-11-2018 IPR019786 Zinc finger, PHD-type, conserved site TOT_040000821 8af096f79a588555152b49656537f1f7 1156 Gene3D G3DSA:3.30.40.10 354 444 2.4E-14 T 01-11-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type TOT_040000821 8af096f79a588555152b49656537f1f7 1156 Pfam PF00628 PHD-finger 557 602 1.5E-11 T 01-11-2018 IPR019787 Zinc finger, PHD-finger TOT_040000821 8af096f79a588555152b49656537f1f7 1156 Gene3D G3DSA:3.30.40.10 496 609 3.0E-20 T 01-11-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type TOT_040000821 8af096f79a588555152b49656537f1f7 1156 SUPERFAMILY SSF57850 389 445 1.95E-15 T 01-11-2018 TOT_040000821 8af096f79a588555152b49656537f1f7 1156 ProSitePatterns PS00518 Zinc finger RING-type signature. 416 425 - T 01-11-2018 IPR017907 Zinc finger, RING-type, conserved site TOT_040000821 8af096f79a588555152b49656537f1f7 1156 Pfam PF13639 Ring finger domain 393 439 5.0E-8 T 01-11-2018 IPR001841 Zinc finger, RING-type TOT_020000413 f0da66d889d4b9781bfa627398e30278 150 Gene3D G3DSA:3.30.70.141 1 150 1.2E-56 T 01-11-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOT_020000413 f0da66d889d4b9781bfa627398e30278 150 SUPERFAMILY SSF54919 1 149 5.63E-54 T 01-11-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOT_020000413 f0da66d889d4b9781bfa627398e30278 150 SMART SM00562 3 140 8.3E-70 T 01-11-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOT_020000413 f0da66d889d4b9781bfa627398e30278 150 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 8.1E-44 T 01-11-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOT_020000413 f0da66d889d4b9781bfa627398e30278 150 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 8.1E-44 T 01-11-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOT_020000413 f0da66d889d4b9781bfa627398e30278 150 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 8.1E-44 T 01-11-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOT_020000413 f0da66d889d4b9781bfa627398e30278 150 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 8.1E-44 T 01-11-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOT_020000413 f0da66d889d4b9781bfa627398e30278 150 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 8.1E-44 T 01-11-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOT_020000413 f0da66d889d4b9781bfa627398e30278 150 Pfam PF00334 Nucleoside diphosphate kinase 4 137 8.4E-51 T 01-11-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOT_020000413 f0da66d889d4b9781bfa627398e30278 150 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 31.605 T 01-11-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOT_040000473 667b8008ba7b1dff1e340e4c41bf78f5 491 TIGRFAM TIGR01040 V-ATPase_V1_B: V-type ATPase, B subunit 30 490 7.1E-257 T 01-11-2018 IPR005723 ATPase, V1 complex, subunit B GO:0015991|GO:0033180 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TOT_040000473 667b8008ba7b1dff1e340e4c41bf78f5 491 SUPERFAMILY SSF52540 104 387 2.34E-81 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_040000473 667b8008ba7b1dff1e340e4c41bf78f5 491 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 373 382 - T 01-11-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TOT_040000473 667b8008ba7b1dff1e340e4c41bf78f5 491 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 34 100 5.4E-12 T 01-11-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TOT_040000473 667b8008ba7b1dff1e340e4c41bf78f5 491 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 28 491 55.073 T 01-11-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TOT_040000473 667b8008ba7b1dff1e340e4c41bf78f5 491 Gene3D G3DSA:3.40.50.12240 26 491 2.1E-184 T 01-11-2018 TOT_040000473 667b8008ba7b1dff1e340e4c41bf78f5 491 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 157 382 4.9E-65 T 01-11-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TOT_040000473 667b8008ba7b1dff1e340e4c41bf78f5 491 PIRSF PIRSF039114 22 491 5.1E-240 T 01-11-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TOT_010000898 c145d0f9ce8e06b3cb3eb6d17f49ed64 125 SMART SM00651 5 76 7.9E-15 T 01-11-2018 IPR001163 LSM domain, eukaryotic/archaea-type TOT_010000898 c145d0f9ce8e06b3cb3eb6d17f49ed64 125 Pfam PF01423 LSM domain 5 75 4.8E-17 T 01-11-2018 IPR001163 LSM domain, eukaryotic/archaea-type TOT_010000898 c145d0f9ce8e06b3cb3eb6d17f49ed64 125 Gene3D G3DSA:2.30.30.100 1 91 2.1E-31 T 01-11-2018 TOT_010000898 c145d0f9ce8e06b3cb3eb6d17f49ed64 125 SUPERFAMILY SSF50182 4 122 1.24E-26 T 01-11-2018 IPR010920 LSM domain superfamily TOT_040000517 b100ad55625222a600cd845b8650de28 136 ProSitePatterns PS00322 Histone H3 signature 1. 15 21 - T 01-11-2018 IPR000164 Histone H3/CENP-A GO:0000786|GO:0003677 TOT_040000517 b100ad55625222a600cd845b8650de28 136 ProSitePatterns PS00959 Histone H3 signature 2. 67 75 - T 01-11-2018 IPR000164 Histone H3/CENP-A GO:0000786|GO:0003677 TOT_040000517 b100ad55625222a600cd845b8650de28 136 PRINTS PR00622 Histone H3 signature 34 55 6.5E-84 T 01-11-2018 IPR000164 Histone H3/CENP-A GO:0000786|GO:0003677 TOT_040000517 b100ad55625222a600cd845b8650de28 136 PRINTS PR00622 Histone H3 signature 17 31 6.5E-84 T 01-11-2018 IPR000164 Histone H3/CENP-A GO:0000786|GO:0003677 TOT_040000517 b100ad55625222a600cd845b8650de28 136 PRINTS PR00622 Histone H3 signature 80 98 6.5E-84 T 01-11-2018 IPR000164 Histone H3/CENP-A GO:0000786|GO:0003677 TOT_040000517 b100ad55625222a600cd845b8650de28 136 PRINTS PR00622 Histone H3 signature 98 114 6.5E-84 T 01-11-2018 IPR000164 Histone H3/CENP-A GO:0000786|GO:0003677 TOT_040000517 b100ad55625222a600cd845b8650de28 136 PRINTS PR00622 Histone H3 signature 58 75 6.5E-84 T 01-11-2018 IPR000164 Histone H3/CENP-A GO:0000786|GO:0003677 TOT_040000517 b100ad55625222a600cd845b8650de28 136 PRINTS PR00622 Histone H3 signature 3 17 6.5E-84 T 01-11-2018 IPR000164 Histone H3/CENP-A GO:0000786|GO:0003677 TOT_040000517 b100ad55625222a600cd845b8650de28 136 PRINTS PR00622 Histone H3 signature 114 135 6.5E-84 T 01-11-2018 IPR000164 Histone H3/CENP-A GO:0000786|GO:0003677 TOT_040000517 b100ad55625222a600cd845b8650de28 136 Pfam PF00125 Core histone H2A/H2B/H3/H4 1 132 1.0E-52 T 01-11-2018 IPR007125 Histone H2A/H2B/H3 GO:0000786|GO:0003677 TOT_040000517 b100ad55625222a600cd845b8650de28 136 Gene3D G3DSA:1.10.20.10 2 136 7.6E-78 T 01-11-2018 IPR009072 Histone-fold GO:0046982 TOT_040000517 b100ad55625222a600cd845b8650de28 136 SMART SM00428 34 136 6.3E-72 T 01-11-2018 IPR000164 Histone H3/CENP-A GO:0000786|GO:0003677 TOT_040000517 b100ad55625222a600cd845b8650de28 136 SUPERFAMILY SSF47113 2 133 8.38E-55 T 01-11-2018 IPR009072 Histone-fold GO:0046982 TOT_040000079 30d078f58235c38321aa764cbb9cee63 229 SMART SM00952 132 189 3.1E-20 T 01-11-2018 IPR013584 RAP domain TOT_040000079 30d078f58235c38321aa764cbb9cee63 229 Pfam PF08373 RAP domain 132 189 9.0E-23 T 01-11-2018 IPR013584 RAP domain TOT_020000067 2671a01858745138e7d2c2a058bfa6c2 268 ProSitePatterns PS01082 Ribosomal protein L7Ae signature. 173 190 - T 01-11-2018 IPR004037 Ribosomal protein L7Ae conserved site GO:0042254|GO:1990904 Reactome: R-HSA-6791226 TOT_020000067 2671a01858745138e7d2c2a058bfa6c2 268 PRINTS PR00882 Ribosomal protein L7A family signature 96 109 6.1E-49 T 01-11-2018 IPR001921 Ribosomal protein L7A/L8 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_020000067 2671a01858745138e7d2c2a058bfa6c2 268 PRINTS PR00882 Ribosomal protein L7A family signature 35 52 6.1E-49 T 01-11-2018 IPR001921 Ribosomal protein L7A/L8 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_020000067 2671a01858745138e7d2c2a058bfa6c2 268 PRINTS PR00882 Ribosomal protein L7A family signature 72 91 6.1E-49 T 01-11-2018 IPR001921 Ribosomal protein L7A/L8 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_020000067 2671a01858745138e7d2c2a058bfa6c2 268 PRINTS PR00882 Ribosomal protein L7A family signature 131 151 6.1E-49 T 01-11-2018 IPR001921 Ribosomal protein L7A/L8 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_020000067 2671a01858745138e7d2c2a058bfa6c2 268 PRINTS PR00882 Ribosomal protein L7A family signature 192 216 6.1E-49 T 01-11-2018 IPR001921 Ribosomal protein L7A/L8 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_020000067 2671a01858745138e7d2c2a058bfa6c2 268 PRINTS PR00882 Ribosomal protein L7A family signature 52 69 6.1E-49 T 01-11-2018 IPR001921 Ribosomal protein L7A/L8 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_020000067 2671a01858745138e7d2c2a058bfa6c2 268 SUPERFAMILY SSF55315 94 217 2.19E-31 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like TOT_020000067 2671a01858745138e7d2c2a058bfa6c2 268 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 180 194 4.1E-22 T 01-11-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TOT_020000067 2671a01858745138e7d2c2a058bfa6c2 268 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 135 149 4.1E-22 T 01-11-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TOT_020000067 2671a01858745138e7d2c2a058bfa6c2 268 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 170 180 4.1E-22 T 01-11-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TOT_020000067 2671a01858745138e7d2c2a058bfa6c2 268 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 154 167 4.1E-22 T 01-11-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TOT_020000067 2671a01858745138e7d2c2a058bfa6c2 268 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 126 207 3.5E-22 T 01-11-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 TOT_020000067 2671a01858745138e7d2c2a058bfa6c2 268 Gene3D G3DSA:3.30.1330.210 56 239 8.8E-78 T 01-11-2018 IPR038524 Ribosomal protein L7A/L8 superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_010000615 36af1367acad9eb0140744845178969f 507 Gene3D G3DSA:3.30.450.60 1 137 3.0E-29 T 01-11-2018 TOT_010000615 36af1367acad9eb0140744845178969f 507 SUPERFAMILY SSF64356 1 134 5.04E-27 T 01-11-2018 IPR011012 Longin-like domain superfamily TOT_010000615 36af1367acad9eb0140744845178969f 507 Gene3D G3DSA:2.60.40.1170 355 503 6.3E-52 T 01-11-2018 TOT_010000615 36af1367acad9eb0140744845178969f 507 PRINTS PR00314 Clathrin coat assembly protein signature 97 124 1.4E-9 T 01-11-2018 IPR001392 Clathrin adaptor, mu subunit GO:0006886|GO:0016192|GO:0030131 TOT_010000615 36af1367acad9eb0140744845178969f 507 PRINTS PR00314 Clathrin coat assembly protein signature 12 32 1.4E-9 T 01-11-2018 IPR001392 Clathrin adaptor, mu subunit GO:0006886|GO:0016192|GO:0030131 TOT_010000615 36af1367acad9eb0140744845178969f 507 Gene3D G3DSA:2.60.40.1170 211 499 6.3E-52 T 01-11-2018 TOT_010000615 36af1367acad9eb0140744845178969f 507 Pfam PF00928 Adaptor complexes medium subunit family 200 504 1.9E-50 T 01-11-2018 IPR028565 Mu homology domain TOT_010000615 36af1367acad9eb0140744845178969f 507 ProSitePatterns PS00991 Clathrin adaptor complexes medium chain signature 2. 333 347 - T 01-11-2018 IPR018240 Clathrin adaptor, mu subunit, conserved site GO:0006886|GO:0016192|GO:0030131 TOT_010000615 36af1367acad9eb0140744845178969f 507 PIRSF PIRSF005992 1 505 1.2E-80 T 01-11-2018 IPR001392 Clathrin adaptor, mu subunit GO:0006886|GO:0016192|GO:0030131 TOT_010000615 36af1367acad9eb0140744845178969f 507 SUPERFAMILY SSF49447 201 503 9.42E-58 T 01-11-2018 IPR036168 AP-2 complex subunit mu, C-terminal superfamily TOT_020000398 2c48ae66a905b6810eba59c7ad90ee03 699 Pfam PF00249 Myb-like DNA-binding domain 617 663 9.2E-7 T 01-11-2018 IPR001005 SANT/Myb domain TOT_020000398 2c48ae66a905b6810eba59c7ad90ee03 699 Gene3D G3DSA:1.10.10.60 608 672 2.6E-11 T 01-11-2018 TOT_020000398 2c48ae66a905b6810eba59c7ad90ee03 699 SUPERFAMILY SSF46689 617 671 1.72E-10 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TOT_020000398 2c48ae66a905b6810eba59c7ad90ee03 699 SMART SM00717 615 666 4.5E-8 T 01-11-2018 IPR001005 SANT/Myb domain TOT_020000970 8879cab51cd26e086805c6592242c8ad 1512 SUPERFAMILY SSF90123 123 425 1.57E-5 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000970 8879cab51cd26e086805c6592242c8ad 1512 SUPERFAMILY SSF52540 1114 1501 5.32E-29 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000970 8879cab51cd26e086805c6592242c8ad 1512 Gene3D G3DSA:3.40.50.300 1216 1510 2.3E-42 T 01-11-2018 TOT_020000970 8879cab51cd26e086805c6592242c8ad 1512 SMART SM00382 1258 1429 0.014 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000970 8879cab51cd26e086805c6592242c8ad 1512 SMART SM00382 542 740 0.47 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000970 8879cab51cd26e086805c6592242c8ad 1512 Pfam PF00664 ABC transporter transmembrane region 886 1096 4.6E-10 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TOT_020000970 8879cab51cd26e086805c6592242c8ad 1512 ProSitePatterns PS00211 ABC transporters family signature. 645 659 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_020000970 8879cab51cd26e086805c6592242c8ad 1512 SUPERFAMILY SSF90123 826 1096 2.62E-15 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000970 8879cab51cd26e086805c6592242c8ad 1512 Pfam PF00005 ABC transporter 533 659 4.8E-13 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000970 8879cab51cd26e086805c6592242c8ad 1512 SUPERFAMILY SSF52540 526 718 1.33E-23 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000970 8879cab51cd26e086805c6592242c8ad 1512 Gene3D G3DSA:3.40.50.300 503 726 5.1E-35 T 01-11-2018 TOT_020000970 8879cab51cd26e086805c6592242c8ad 1512 Pfam PF00005 ABC transporter 1249 1427 1.5E-18 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_010000631 1e71577f4eaf5e1ada565395de2af5fe 441 Gene3D G3DSA:2.60.40.1170 291 439 2.5E-92 T 01-11-2018 TOT_010000631 1e71577f4eaf5e1ada565395de2af5fe 441 Pfam PF00928 Adaptor complexes medium subunit family 157 439 7.8E-78 T 01-11-2018 IPR028565 Mu homology domain TOT_010000631 1e71577f4eaf5e1ada565395de2af5fe 441 PRINTS PR00314 Clathrin coat assembly protein signature 159 187 5.8E-57 T 01-11-2018 IPR001392 Clathrin adaptor, mu subunit GO:0006886|GO:0016192|GO:0030131 TOT_010000631 1e71577f4eaf5e1ada565395de2af5fe 441 PRINTS PR00314 Clathrin coat assembly protein signature 358 369 5.8E-57 T 01-11-2018 IPR001392 Clathrin adaptor, mu subunit GO:0006886|GO:0016192|GO:0030131 TOT_010000631 1e71577f4eaf5e1ada565395de2af5fe 441 PRINTS PR00314 Clathrin coat assembly protein signature 249 276 5.8E-57 T 01-11-2018 IPR001392 Clathrin adaptor, mu subunit GO:0006886|GO:0016192|GO:0030131 TOT_010000631 1e71577f4eaf5e1ada565395de2af5fe 441 PRINTS PR00314 Clathrin coat assembly protein signature 318 333 5.8E-57 T 01-11-2018 IPR001392 Clathrin adaptor, mu subunit GO:0006886|GO:0016192|GO:0030131 TOT_010000631 1e71577f4eaf5e1ada565395de2af5fe 441 PRINTS PR00314 Clathrin coat assembly protein signature 14 34 5.8E-57 T 01-11-2018 IPR001392 Clathrin adaptor, mu subunit GO:0006886|GO:0016192|GO:0030131 TOT_010000631 1e71577f4eaf5e1ada565395de2af5fe 441 PRINTS PR00314 Clathrin coat assembly protein signature 100 127 5.8E-57 T 01-11-2018 IPR001392 Clathrin adaptor, mu subunit GO:0006886|GO:0016192|GO:0030131 TOT_010000631 1e71577f4eaf5e1ada565395de2af5fe 441 ProSitePatterns PS00991 Clathrin adaptor complexes medium chain signature 2. 269 283 - T 01-11-2018 IPR018240 Clathrin adaptor, mu subunit, conserved site GO:0006886|GO:0016192|GO:0030131 TOT_010000631 1e71577f4eaf5e1ada565395de2af5fe 441 PIRSF PIRSF005992 3 441 6.0E-126 T 01-11-2018 IPR001392 Clathrin adaptor, mu subunit GO:0006886|GO:0016192|GO:0030131 TOT_010000631 1e71577f4eaf5e1ada565395de2af5fe 441 Gene3D G3DSA:2.60.40.1170 164 435 2.5E-92 T 01-11-2018 TOT_010000631 1e71577f4eaf5e1ada565395de2af5fe 441 ProSitePatterns PS00990 Clathrin adaptor complexes medium chain signature 1. 157 177 - T 01-11-2018 IPR018240 Clathrin adaptor, mu subunit, conserved site GO:0006886|GO:0016192|GO:0030131 TOT_010000631 1e71577f4eaf5e1ada565395de2af5fe 441 Pfam PF01217 Clathrin adaptor complex small chain 62 123 8.4E-6 T 01-11-2018 IPR022775 AP complex, mu/sigma subunit TOT_010000631 1e71577f4eaf5e1ada565395de2af5fe 441 SUPERFAMILY SSF64356 4 139 9.39E-39 T 01-11-2018 IPR011012 Longin-like domain superfamily TOT_010000631 1e71577f4eaf5e1ada565395de2af5fe 441 SUPERFAMILY SSF49447 157 439 4.71E-88 T 01-11-2018 IPR036168 AP-2 complex subunit mu, C-terminal superfamily TOT_010000631 1e71577f4eaf5e1ada565395de2af5fe 441 Gene3D G3DSA:3.30.450.60 3 142 1.1E-47 T 01-11-2018 TOT_040000745 e33d8e98e9bcd48c2e080bed947de925 145 Pfam PF04178 Got1/Sft2-like family 16 118 1.4E-6 T 01-11-2018 IPR007305 Vesicle transport protein, Got1/SFT2-like GO:0016192 TOT_040000034 225ce4f5c68199fa7ea109e40ce761a4 1160 Gene3D G3DSA:3.30.70.330 799 883 6.5E-6 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_040000034 225ce4f5c68199fa7ea109e40ce761a4 1160 Gene3D G3DSA:1.25.40.10 248 551 5.1E-17 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TOT_040000034 225ce4f5c68199fa7ea109e40ce761a4 1160 SMART SM00360 1033 1104 2.1E-12 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_040000034 225ce4f5c68199fa7ea109e40ce761a4 1160 SMART SM00360 807 873 0.038 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_040000034 225ce4f5c68199fa7ea109e40ce761a4 1160 SUPERFAMILY SSF54928 802 879 7.06E-8 T 01-11-2018 IPR035979 RNA-binding domain superfamily GO:0003676 TOT_040000034 225ce4f5c68199fa7ea109e40ce761a4 1160 SUPERFAMILY SSF48452 25 444 3.22E-31 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TOT_040000034 225ce4f5c68199fa7ea109e40ce761a4 1160 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 1034 1085 6.8E-11 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_040000034 225ce4f5c68199fa7ea109e40ce761a4 1160 SMART SM00386 261 294 42.0 T 01-11-2018 IPR003107 HAT (Half-A-TPR) repeat GO:0006396 TOT_040000034 225ce4f5c68199fa7ea109e40ce761a4 1160 SMART SM00386 167 200 160.0 T 01-11-2018 IPR003107 HAT (Half-A-TPR) repeat GO:0006396 TOT_040000034 225ce4f5c68199fa7ea109e40ce761a4 1160 SMART SM00386 82 113 26.0 T 01-11-2018 IPR003107 HAT (Half-A-TPR) repeat GO:0006396 TOT_040000034 225ce4f5c68199fa7ea109e40ce761a4 1160 SMART SM00386 119 155 40.0 T 01-11-2018 IPR003107 HAT (Half-A-TPR) repeat GO:0006396 TOT_040000034 225ce4f5c68199fa7ea109e40ce761a4 1160 SMART SM00386 295 327 130.0 T 01-11-2018 IPR003107 HAT (Half-A-TPR) repeat GO:0006396 TOT_040000034 225ce4f5c68199fa7ea109e40ce761a4 1160 Gene3D G3DSA:3.30.70.330 1003 1120 2.3E-15 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_040000034 225ce4f5c68199fa7ea109e40ce761a4 1160 SUPERFAMILY SSF54928 1013 1118 4.34E-17 T 01-11-2018 IPR035979 RNA-binding domain superfamily GO:0003676 TOT_040000034 225ce4f5c68199fa7ea109e40ce761a4 1160 Gene3D G3DSA:1.25.40.10 24 207 4.9E-27 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TOT_010000605 e6a95497864b1741bef12c2555af7bc3 1309 Pfam PF17405 Nrap protein nucleotidyltransferase domain 4 739 835 1.9E-10 T 01-11-2018 IPR035369 Nrap protein, domain 4 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TOT_030000475 a02d092bb287cd08e5f9a75aa5eb1f89 520 Pfam PF00382 Transcription factor TFIIB repeat 181 253 1.0E-9 T 01-11-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 TOT_030000475 a02d092bb287cd08e5f9a75aa5eb1f89 520 Pfam PF00382 Transcription factor TFIIB repeat 86 156 1.9E-12 T 01-11-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 TOT_030000475 a02d092bb287cd08e5f9a75aa5eb1f89 520 SUPERFAMILY SSF47954 82 172 3.29E-24 T 01-11-2018 IPR036915 Cyclin-like superfamily TOT_030000475 a02d092bb287cd08e5f9a75aa5eb1f89 520 Pfam PF07741 Brf1-like TBP-binding domain 417 516 3.6E-12 T 01-11-2018 IPR011665 Brf1, TBP-binding domain Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066 TOT_030000475 a02d092bb287cd08e5f9a75aa5eb1f89 520 Gene3D G3DSA:2.20.25.10 1 43 5.1E-7 T 01-11-2018 TOT_030000475 a02d092bb287cd08e5f9a75aa5eb1f89 520 Gene3D G3DSA:1.10.472.10 71 174 6.9E-28 T 01-11-2018 TOT_030000475 a02d092bb287cd08e5f9a75aa5eb1f89 520 SMART SM00385 178 262 1.1 T 01-11-2018 IPR013763 Cyclin-like TOT_030000475 a02d092bb287cd08e5f9a75aa5eb1f89 520 SMART SM00385 84 165 1.0E-4 T 01-11-2018 IPR013763 Cyclin-like TOT_030000475 a02d092bb287cd08e5f9a75aa5eb1f89 520 SUPERFAMILY SSF47954 174 283 1.79E-21 T 01-11-2018 IPR036915 Cyclin-like superfamily TOT_030000475 a02d092bb287cd08e5f9a75aa5eb1f89 520 SUPERFAMILY SSF57783 3 47 8.5E-9 T 01-11-2018 TOT_030000475 a02d092bb287cd08e5f9a75aa5eb1f89 520 PRINTS PR00685 Transcription initiation factor IIB signature 126 145 1.1E-10 T 01-11-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TOT_030000475 a02d092bb287cd08e5f9a75aa5eb1f89 520 PRINTS PR00685 Transcription initiation factor IIB signature 216 232 1.1E-10 T 01-11-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TOT_030000475 a02d092bb287cd08e5f9a75aa5eb1f89 520 PRINTS PR00685 Transcription initiation factor IIB signature 18 38 1.1E-10 T 01-11-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TOT_030000475 a02d092bb287cd08e5f9a75aa5eb1f89 520 PRINTS PR00685 Transcription initiation factor IIB signature 152 167 1.1E-10 T 01-11-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TOT_030000475 a02d092bb287cd08e5f9a75aa5eb1f89 520 Gene3D G3DSA:1.10.472.10 177 283 5.7E-21 T 01-11-2018 TOT_010001264 d1b3a62842185849a7fe0cfa5d10090f 1162 ProSitePatterns PS00916 Phosphatidylinositol 3- and 4-kinases signature 2. 1014 1034 - T 01-11-2018 IPR018936 Phosphatidylinositol 3/4-kinase, conserved site GO:0016301 TOT_010001264 d1b3a62842185849a7fe0cfa5d10090f 1162 Gene3D G3DSA:3.30.1010.10 658 838 2.6E-5 T 01-11-2018 TOT_010001264 d1b3a62842185849a7fe0cfa5d10090f 1162 Pfam PF00454 Phosphatidylinositol 3- and 4-kinase 1006 1105 5.9E-13 T 01-11-2018 IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain TOT_010001264 d1b3a62842185849a7fe0cfa5d10090f 1162 Gene3D G3DSA:1.10.1070.11 982 1162 5.6E-30 T 01-11-2018 IPR036940 Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily GO:0016301 TOT_010001264 d1b3a62842185849a7fe0cfa5d10090f 1162 SMART SM00146 788 1160 1.6E-9 T 01-11-2018 IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain TOT_010001264 d1b3a62842185849a7fe0cfa5d10090f 1162 SUPERFAMILY SSF56112 713 1154 7.04E-27 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily TOT_040000254 206cd682c7585e4e9ce8bcbfb84df718 103 Gene3D G3DSA:1.10.20.10 2 103 5.2E-58 T 01-11-2018 IPR009072 Histone-fold GO:0046982 TOT_040000254 206cd682c7585e4e9ce8bcbfb84df718 103 PRINTS PR00623 Histone H4 signature 5 16 3.1E-61 T 01-11-2018 IPR001951 Histone H4 GO:0000786|GO:0003677|GO:0005634 TOT_040000254 206cd682c7585e4e9ce8bcbfb84df718 103 PRINTS PR00623 Histone H4 signature 89 100 3.1E-61 T 01-11-2018 IPR001951 Histone H4 GO:0000786|GO:0003677|GO:0005634 TOT_040000254 206cd682c7585e4e9ce8bcbfb84df718 103 PRINTS PR00623 Histone H4 signature 40 60 3.1E-61 T 01-11-2018 IPR001951 Histone H4 GO:0000786|GO:0003677|GO:0005634 TOT_040000254 206cd682c7585e4e9ce8bcbfb84df718 103 PRINTS PR00623 Histone H4 signature 62 76 3.1E-61 T 01-11-2018 IPR001951 Histone H4 GO:0000786|GO:0003677|GO:0005634 TOT_040000254 206cd682c7585e4e9ce8bcbfb84df718 103 PRINTS PR00623 Histone H4 signature 20 39 3.1E-61 T 01-11-2018 IPR001951 Histone H4 GO:0000786|GO:0003677|GO:0005634 TOT_040000254 206cd682c7585e4e9ce8bcbfb84df718 103 PRINTS PR00623 Histone H4 signature 77 89 3.1E-61 T 01-11-2018 IPR001951 Histone H4 GO:0000786|GO:0003677|GO:0005634 TOT_040000254 206cd682c7585e4e9ce8bcbfb84df718 103 SMART SM00417 16 90 7.4E-27 T 01-11-2018 IPR001951 Histone H4 GO:0000786|GO:0003677|GO:0005634 TOT_040000254 206cd682c7585e4e9ce8bcbfb84df718 103 SUPERFAMILY SSF47113 3 102 4.37E-30 T 01-11-2018 IPR009072 Histone-fold GO:0046982 TOT_040000254 206cd682c7585e4e9ce8bcbfb84df718 103 Pfam PF15511 Centromere kinetochore component CENP-T histone fold 32 96 2.0E-9 T 01-11-2018 IPR035425 CENP-T/Histone H4, histone fold Reactome: R-HSA-606279 TOT_040000254 206cd682c7585e4e9ce8bcbfb84df718 103 ProSitePatterns PS00047 Histone H4 signature. 15 19 - T 01-11-2018 IPR019809 Histone H4, conserved site GO:0000786|GO:0003677|GO:0005634|GO:0006334 Reactome: R-HSA-1221632|Reactome: R-HSA-171306|Reactome: R-HSA-1912408|Reactome: R-HSA-201722|Reactome: R-HSA-212300|Reactome: R-HSA-2299718|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559586|Reactome: R-HSA-3214815|Reactome: R-HSA-3214841|Reactome: R-HSA-3214842|Reactome: R-HSA-3214847|Reactome: R-HSA-3214858|Reactome: R-HSA-427359|Reactome: R-HSA-427389|Reactome: R-HSA-427413|Reactome: R-HSA-4551638|Reactome: R-HSA-5250924|Reactome: R-HSA-5334118|Reactome: R-HSA-5578749|Reactome: R-HSA-5617472|Reactome: R-HSA-5625886|Reactome: R-HSA-5693565|Reactome: R-HSA-5693571|Reactome: R-HSA-5693607|Reactome: R-HSA-606279|Reactome: R-HSA-69473|Reactome: R-HSA-73728|Reactome: R-HSA-73777|Reactome: R-HSA-8936459|Reactome: R-HSA-8939236|Reactome: R-HSA-9018519|Reactome: R-HSA-912446|Reactome: R-HSA-977225 TOT_040000891 f7d986da45229e4f667ca305bc46429b 826 Pfam PF04385 Domain of unknown function, DUF529 624 681 3.7E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000687 2a63922c32002802f72bbb03ee41a25a 1785 Pfam PF08514 STAG domain 256 339 3.0E-9 T 01-11-2018 IPR013721 STAG TOT_020000006 c07344d3348acfc5610ca560a6555e85 1527 Pfam PF00005 ABC transporter 1254 1441 1.0E-17 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000006 c07344d3348acfc5610ca560a6555e85 1527 Gene3D G3DSA:1.20.1560.10 819 1157 1.4E-11 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000006 c07344d3348acfc5610ca560a6555e85 1527 Gene3D G3DSA:3.40.50.300 494 768 3.1E-35 T 01-11-2018 TOT_020000006 c07344d3348acfc5610ca560a6555e85 1527 SUPERFAMILY SSF90123 837 1155 5.76E-21 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000006 c07344d3348acfc5610ca560a6555e85 1527 Pfam PF00005 ABC transporter 532 658 6.6E-13 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000006 c07344d3348acfc5610ca560a6555e85 1527 SMART SM00382 541 741 0.04 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000006 c07344d3348acfc5610ca560a6555e85 1527 SMART SM00382 1263 1517 0.12 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000006 c07344d3348acfc5610ca560a6555e85 1527 SUPERFAMILY SSF52540 1217 1514 3.29E-26 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000006 c07344d3348acfc5610ca560a6555e85 1527 ProSitePatterns PS00211 ABC transporters family signature. 644 658 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_020000006 c07344d3348acfc5610ca560a6555e85 1527 SUPERFAMILY SSF52540 530 707 5.5E-23 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_040000929 6c2ebd0caebc8610adde82cad2990498 421 SUPERFAMILY SSF56112 101 417 1.48E-78 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily TOT_040000929 6c2ebd0caebc8610adde82cad2990498 421 SMART SM00220 127 412 2.9E-73 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOT_040000929 6c2ebd0caebc8610adde82cad2990498 421 Gene3D G3DSA:3.30.200.20 127 203 8.3E-105 T 01-11-2018 TOT_040000929 6c2ebd0caebc8610adde82cad2990498 421 Gene3D G3DSA:1.10.510.10 204 412 8.3E-105 T 01-11-2018 TOT_040000929 6c2ebd0caebc8610adde82cad2990498 421 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 133 156 - T 01-11-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TOT_040000929 6c2ebd0caebc8610adde82cad2990498 421 Pfam PF00069 Protein kinase domain 127 412 5.5E-65 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOT_040000929 6c2ebd0caebc8610adde82cad2990498 421 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 240 252 - T 01-11-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TOT_020000656 4685778ce2d446f5683a93c96037b89e 1516 Gene3D G3DSA:3.40.50.300 1221 1511 1.0E-43 T 01-11-2018 TOT_020000656 4685778ce2d446f5683a93c96037b89e 1516 SMART SM00382 542 742 0.03 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000656 4685778ce2d446f5683a93c96037b89e 1516 SMART SM00382 1261 1432 0.36 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000656 4685778ce2d446f5683a93c96037b89e 1516 SUPERFAMILY SSF52540 526 716 1.45E-24 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000656 4685778ce2d446f5683a93c96037b89e 1516 Pfam PF00005 ABC transporter 533 660 3.2E-12 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000656 4685778ce2d446f5683a93c96037b89e 1516 Pfam PF00005 ABC transporter 1252 1430 3.7E-17 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000656 4685778ce2d446f5683a93c96037b89e 1516 SUPERFAMILY SSF90123 833 1145 2.88E-22 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000656 4685778ce2d446f5683a93c96037b89e 1516 Gene3D G3DSA:3.40.50.300 488 780 9.2E-38 T 01-11-2018 TOT_020000656 4685778ce2d446f5683a93c96037b89e 1516 ProSitePatterns PS00211 ABC transporters family signature. 645 659 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_020000656 4685778ce2d446f5683a93c96037b89e 1516 Gene3D G3DSA:1.20.1560.10 818 1156 6.5E-11 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000656 4685778ce2d446f5683a93c96037b89e 1516 SUPERFAMILY SSF52540 1228 1501 4.95E-27 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_030000330 4ad5a3561687d7cc05cec5a070a2ce1c 1251 SMART SM00248 1045 1074 0.0014 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 TOT_030000330 4ad5a3561687d7cc05cec5a070a2ce1c 1251 SMART SM00248 1012 1041 2.4E-5 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 TOT_030000330 4ad5a3561687d7cc05cec5a070a2ce1c 1251 SMART SM00248 1220 1251 3900.0 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 TOT_030000330 4ad5a3561687d7cc05cec5a070a2ce1c 1251 SMART SM00248 979 1008 8.2E-5 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 TOT_030000330 4ad5a3561687d7cc05cec5a070a2ce1c 1251 SUPERFAMILY SSF82199 387 435 6.54E-5 T 01-11-2018 TOT_030000330 4ad5a3561687d7cc05cec5a070a2ce1c 1251 Gene3D G3DSA:2.170.270.10 169 435 6.3E-10 T 01-11-2018 TOT_030000330 4ad5a3561687d7cc05cec5a070a2ce1c 1251 Gene3D G3DSA:3.30.60.180 208 273 6.3E-10 T 01-11-2018 TOT_030000330 4ad5a3561687d7cc05cec5a070a2ce1c 1251 Pfam PF13637 Ankyrin repeats (many copies) 982 1033 4.3E-12 T 01-11-2018 TOT_030000330 4ad5a3561687d7cc05cec5a070a2ce1c 1251 SUPERFAMILY SSF48403 955 1085 4.04E-28 T 01-11-2018 IPR036770 Ankyrin repeat-containing domain superfamily TOT_030000330 4ad5a3561687d7cc05cec5a070a2ce1c 1251 Gene3D G3DSA:1.25.40.20 947 1089 6.5E-31 T 01-11-2018 IPR036770 Ankyrin repeat-containing domain superfamily TOT_030000330 4ad5a3561687d7cc05cec5a070a2ce1c 1251 Gene3D G3DSA:3.30.70.3410 274 372 6.3E-10 T 01-11-2018 TOT_010001295 2abac82956176e319d0b23607d032576 1172 Pfam PF00613 Phosphoinositide 3-kinase family, accessory domain (PIK domain) 112 197 3.1E-9 T 01-11-2018 IPR001263 Phosphoinositide 3-kinase, accessory (PIK) domain TOT_010001295 2abac82956176e319d0b23607d032576 1172 ProSitePatterns PS00916 Phosphatidylinositol 3- and 4-kinases signature 2. 1009 1029 - T 01-11-2018 IPR018936 Phosphatidylinositol 3/4-kinase, conserved site GO:0016301 TOT_010001295 2abac82956176e319d0b23607d032576 1172 SUPERFAMILY SSF56112 420 1166 2.3E-70 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily TOT_010001295 2abac82956176e319d0b23607d032576 1172 Gene3D G3DSA:1.25.40.70 82 196 7.2E-8 T 01-11-2018 TOT_010001295 2abac82956176e319d0b23607d032576 1172 ProSitePatterns PS00915 Phosphatidylinositol 3- and 4-kinases signature 1. 919 933 - T 01-11-2018 IPR018936 Phosphatidylinositol 3/4-kinase, conserved site GO:0016301 TOT_010001295 2abac82956176e319d0b23607d032576 1172 Gene3D G3DSA:1.10.1070.11 976 1171 7.4E-58 T 01-11-2018 IPR036940 Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily GO:0016301 TOT_010001295 2abac82956176e319d0b23607d032576 1172 Gene3D G3DSA:3.30.1010.10 879 969 2.9E-9 T 01-11-2018 TOT_010001295 2abac82956176e319d0b23607d032576 1172 Pfam PF00454 Phosphatidylinositol 3- and 4-kinase 998 1111 3.3E-24 T 01-11-2018 IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain TOT_010001295 2abac82956176e319d0b23607d032576 1172 SMART SM00146 916 1170 3.9E-77 T 01-11-2018 IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain TOT_010001295 2abac82956176e319d0b23607d032576 1172 SUPERFAMILY SSF48371 98 183 6.33E-12 T 01-11-2018 IPR016024 Armadillo-type fold TOT_030000512 8e0546d44c2718c58d6e658d23105d6d 566 Pfam PF07690 Major Facilitator Superfamily 69 505 1.3E-21 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOT_030000512 8e0546d44c2718c58d6e658d23105d6d 566 Gene3D G3DSA:1.20.1250.20 349 555 4.9E-10 T 01-11-2018 TOT_030000512 8e0546d44c2718c58d6e658d23105d6d 566 Gene3D G3DSA:1.20.1250.20 40 237 1.1E-19 T 01-11-2018 TOT_030000512 8e0546d44c2718c58d6e658d23105d6d 566 SUPERFAMILY SSF103473 41 550 1.96E-45 T 01-11-2018 IPR036259 MFS transporter superfamily TOT_010000004 ec97135b1d5fbbb76a6c84ca42fe38e8 1521 Gene3D G3DSA:1.20.1560.10 812 1157 4.6E-9 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_010000004 ec97135b1d5fbbb76a6c84ca42fe38e8 1521 Pfam PF00005 ABC transporter 534 660 4.5E-12 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_010000004 ec97135b1d5fbbb76a6c84ca42fe38e8 1521 SUPERFAMILY SSF52540 528 719 6.48E-22 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010000004 ec97135b1d5fbbb76a6c84ca42fe38e8 1521 SUPERFAMILY SSF90123 834 1139 2.22E-20 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_010000004 ec97135b1d5fbbb76a6c84ca42fe38e8 1521 SUPERFAMILY SSF52540 1177 1511 1.85E-26 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010000004 ec97135b1d5fbbb76a6c84ca42fe38e8 1521 Pfam PF00664 ABC transporter transmembrane region 863 1115 2.1E-7 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TOT_010000004 ec97135b1d5fbbb76a6c84ca42fe38e8 1521 Pfam PF00005 ABC transporter 1255 1439 8.4E-16 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_010000004 ec97135b1d5fbbb76a6c84ca42fe38e8 1521 Gene3D G3DSA:3.40.50.300 488 779 2.0E-33 T 01-11-2018 TOT_010000004 ec97135b1d5fbbb76a6c84ca42fe38e8 1521 SMART SM00382 543 750 0.46 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_010000004 ec97135b1d5fbbb76a6c84ca42fe38e8 1521 SMART SM00382 1264 1440 0.04 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_010000004 ec97135b1d5fbbb76a6c84ca42fe38e8 1521 ProSitePatterns PS00211 ABC transporters family signature. 646 660 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_030000544 4f1482cd15c6a249e198f56f913a7755 377 Pfam PF04161 Arv1-like family 3 327 7.8E-21 T 01-11-2018 IPR007290 Arv1 protein Reactome: R-HSA-191273 TOT_030000324 dd5b58516e3943a299733164b490d6d5 877 PRINTS PR01183 Ribonucleotide reductase large chain signature 509 532 1.2E-57 T 01-11-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TOT_030000324 dd5b58516e3943a299733164b490d6d5 877 PRINTS PR01183 Ribonucleotide reductase large chain signature 547 569 1.2E-57 T 01-11-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TOT_030000324 dd5b58516e3943a299733164b490d6d5 877 PRINTS PR01183 Ribonucleotide reductase large chain signature 340 359 1.2E-57 T 01-11-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TOT_030000324 dd5b58516e3943a299733164b490d6d5 877 PRINTS PR01183 Ribonucleotide reductase large chain signature 575 598 1.2E-57 T 01-11-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TOT_030000324 dd5b58516e3943a299733164b490d6d5 877 PRINTS PR01183 Ribonucleotide reductase large chain signature 470 481 1.2E-57 T 01-11-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TOT_030000324 dd5b58516e3943a299733164b490d6d5 877 PRINTS PR01183 Ribonucleotide reductase large chain signature 641 668 1.2E-57 T 01-11-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TOT_030000324 dd5b58516e3943a299733164b490d6d5 877 Gene3D G3DSA:3.20.70.20 122 798 9.6E-295 T 01-11-2018 TOT_030000324 dd5b58516e3943a299733164b490d6d5 877 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 630 652 - T 01-11-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TOT_030000324 dd5b58516e3943a299733164b490d6d5 877 SUPERFAMILY SSF51998 262 800 1.65E-192 T 01-11-2018 TOT_030000324 dd5b58516e3943a299733164b490d6d5 877 Pfam PF02867 Ribonucleotide reductase, barrel domain 263 787 3.1E-187 T 01-11-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TOT_030000324 dd5b58516e3943a299733164b490d6d5 877 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 189 259 1.1E-22 T 01-11-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TOT_030000324 dd5b58516e3943a299733164b490d6d5 877 SUPERFAMILY SSF48168 55 261 3.66E-62 T 01-11-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TOT_030000324 dd5b58516e3943a299733164b490d6d5 877 Pfam PF03477 ATP cone domain 50 137 1.8E-10 T 01-11-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 TOT_030000324 dd5b58516e3943a299733164b490d6d5 877 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 192 791 8.8E-216 T 01-11-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TOT_040000816 edafcf66ca0a0981af309b9af90efbff 1102 SUPERFAMILY SSF51905 1 229 1.04E-8 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TOT_040000816 edafcf66ca0a0981af309b9af90efbff 1102 PRINTS PR00891 Rab GDI/REP protein family signature 214 230 1.4E-11 T 01-11-2018 IPR018203 GDP dissociation inhibitor GO:0005092|GO:0007264 Reactome: R-HSA-8876198 TOT_040000816 edafcf66ca0a0981af309b9af90efbff 1102 PRINTS PR00891 Rab GDI/REP protein family signature 25 42 1.4E-11 T 01-11-2018 IPR018203 GDP dissociation inhibitor GO:0005092|GO:0007264 Reactome: R-HSA-8876198 TOT_040000816 edafcf66ca0a0981af309b9af90efbff 1102 PRINTS PR00891 Rab GDI/REP protein family signature 7 25 1.4E-11 T 01-11-2018 IPR018203 GDP dissociation inhibitor GO:0005092|GO:0007264 Reactome: R-HSA-8876198 TOT_040000816 edafcf66ca0a0981af309b9af90efbff 1102 PRINTS PR00891 Rab GDI/REP protein family signature 197 214 1.4E-11 T 01-11-2018 IPR018203 GDP dissociation inhibitor GO:0005092|GO:0007264 Reactome: R-HSA-8876198 TOT_040000816 edafcf66ca0a0981af309b9af90efbff 1102 Gene3D G3DSA:3.50.50.60 1 95 6.1E-14 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TOT_040000816 edafcf66ca0a0981af309b9af90efbff 1102 Gene3D G3DSA:3.50.50.60 509 660 1.4E-8 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TOT_040000816 edafcf66ca0a0981af309b9af90efbff 1102 Pfam PF00996 GDP dissociation inhibitor 5 54 2.2E-9 T 01-11-2018 IPR018203 GDP dissociation inhibitor GO:0005092|GO:0007264 Reactome: R-HSA-8876198 TOT_040000816 edafcf66ca0a0981af309b9af90efbff 1102 SUPERFAMILY SSF51905 188 588 2.85E-5 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TOT_020001087 cb6addc14b7e990368fa7511e66e5de0 188 Hamap MF_00273 50S ribosomal protein L18Ae [rpl18a]. 40 140 36.768 T 01-11-2018 IPR028877 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_020001087 cb6addc14b7e990368fa7511e66e5de0 188 Gene3D G3DSA:3.10.20.10 84 157 2.5E-36 T 01-11-2018 TOT_020001087 cb6addc14b7e990368fa7511e66e5de0 188 SUPERFAMILY SSF160374 84 157 4.05E-25 T 01-11-2018 TOT_020001087 cb6addc14b7e990368fa7511e66e5de0 188 PIRSF PIRSF002190 13 188 3.9E-75 T 01-11-2018 IPR021138 60S ribosomal protein L18a/ L20, eukaryotes GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_020001087 cb6addc14b7e990368fa7511e66e5de0 188 Pfam PF01775 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A 18 139 7.6E-53 T 01-11-2018 IPR023573 Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_020001087 cb6addc14b7e990368fa7511e66e5de0 188 Gene3D G3DSA:3.10.20.10 6 82 2.9E-30 T 01-11-2018 TOT_020000240 ba420dad17bb6a1caecca202e8fc5eeb 1184 SUPERFAMILY SSF63411 996 1165 1.95E-20 T 01-11-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TOT_020000240 ba420dad17bb6a1caecca202e8fc5eeb 1184 Gene3D G3DSA:3.30.830.10 703 991 4.6E-75 T 01-11-2018 TOT_020000240 ba420dad17bb6a1caecca202e8fc5eeb 1184 SUPERFAMILY SSF63411 457 692 1.01E-42 T 01-11-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TOT_020000240 ba420dad17bb6a1caecca202e8fc5eeb 1184 SMART SM01264 637 908 8.4E-41 T 01-11-2018 IPR013578 Peptidase M16C associated GO:0006508 Reactome: R-HSA-1268020 TOT_020000240 ba420dad17bb6a1caecca202e8fc5eeb 1184 Gene3D G3DSA:3.30.830.10 116 388 1.8E-60 T 01-11-2018 TOT_020000240 ba420dad17bb6a1caecca202e8fc5eeb 1184 Gene3D G3DSA:3.30.830.10 692 1152 4.6E-75 T 01-11-2018 TOT_020000240 ba420dad17bb6a1caecca202e8fc5eeb 1184 Pfam PF00675 Insulinase (Peptidase family M16) 187 265 4.6E-6 T 01-11-2018 IPR011765 Peptidase M16, N-terminal TOT_020000240 ba420dad17bb6a1caecca202e8fc5eeb 1184 Pfam PF05193 Peptidase M16 inactive domain 344 554 8.1E-17 T 01-11-2018 IPR007863 Peptidase M16, C-terminal TOT_020000240 ba420dad17bb6a1caecca202e8fc5eeb 1184 SUPERFAMILY SSF63411 140 386 1.05E-28 T 01-11-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TOT_020000240 ba420dad17bb6a1caecca202e8fc5eeb 1184 Pfam PF08367 Peptidase M16C associated 639 907 1.3E-36 T 01-11-2018 IPR013578 Peptidase M16C associated GO:0006508 Reactome: R-HSA-1268020 TOT_020000240 ba420dad17bb6a1caecca202e8fc5eeb 1184 Gene3D G3DSA:3.30.830.10 408 657 1.3E-65 T 01-11-2018 TOT_020000240 ba420dad17bb6a1caecca202e8fc5eeb 1184 SUPERFAMILY SSF63411 695 968 2.85E-51 T 01-11-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TOT_010000908 7503350950b2dc9028f97b98f8e4f19a 400 ProSitePatterns PS01186 EGF-like domain signature 2. 121 135 - T 01-11-2018 IPR013032 EGF-like, conserved site TOT_030000154 2eb4b58e1ba378ae94c41bfc374cd89e 142 Gene3D G3DSA:3.30.1330.30 7 139 1.1E-49 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like TOT_030000154 2eb4b58e1ba378ae94c41bfc374cd89e 142 ProSitePatterns PS01189 Ribosomal protein S12e signature. 25 43 - T 01-11-2018 IPR000530 Ribosomal protein S12e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_030000154 2eb4b58e1ba378ae94c41bfc374cd89e 142 PRINTS PR00972 Ribosomal protein S12E family signature 29 42 5.7E-17 T 01-11-2018 IPR000530 Ribosomal protein S12e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_030000154 2eb4b58e1ba378ae94c41bfc374cd89e 142 PRINTS PR00972 Ribosomal protein S12E family signature 43 59 5.7E-17 T 01-11-2018 IPR000530 Ribosomal protein S12e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_030000154 2eb4b58e1ba378ae94c41bfc374cd89e 142 PRINTS PR00972 Ribosomal protein S12E family signature 110 123 5.7E-17 T 01-11-2018 IPR000530 Ribosomal protein S12e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_030000154 2eb4b58e1ba378ae94c41bfc374cd89e 142 PRINTS PR00972 Ribosomal protein S12E family signature 85 106 5.7E-17 T 01-11-2018 IPR000530 Ribosomal protein S12e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_030000154 2eb4b58e1ba378ae94c41bfc374cd89e 142 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 25 115 7.3E-22 T 01-11-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 TOT_030000154 2eb4b58e1ba378ae94c41bfc374cd89e 142 SUPERFAMILY SSF55315 16 140 8.64E-25 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like TOT_020000280 1a71eaf66c759480b620035b29e349a5 476 Gene3D G3DSA:3.30.1370.10 303 392 1.7E-8 T 01-11-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TOT_020000280 1a71eaf66c759480b620035b29e349a5 476 SUPERFAMILY SSF54791 306 387 2.28E-6 T 01-11-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TOT_020000280 1a71eaf66c759480b620035b29e349a5 476 SUPERFAMILY SSF54928 146 217 1.56E-6 T 01-11-2018 IPR035979 RNA-binding domain superfamily GO:0003676 TOT_020000655 8c808c68c6461fdb52c732f01f4edb27 1545 SMART SM00382 573 792 0.75 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000655 8c808c68c6461fdb52c732f01f4edb27 1545 SMART SM00382 1292 1526 0.0094 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000655 8c808c68c6461fdb52c732f01f4edb27 1545 Pfam PF00005 ABC transporter 564 691 3.3E-12 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000655 8c808c68c6461fdb52c732f01f4edb27 1545 ProSitePatterns PS00211 ABC transporters family signature. 676 690 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_020000655 8c808c68c6461fdb52c732f01f4edb27 1545 SUPERFAMILY SSF90123 154 440 1.53E-7 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000655 8c808c68c6461fdb52c732f01f4edb27 1545 SUPERFAMILY SSF52540 1275 1535 8.44E-27 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000655 8c808c68c6461fdb52c732f01f4edb27 1545 Gene3D G3DSA:1.20.1560.10 852 1165 5.0E-10 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000655 8c808c68c6461fdb52c732f01f4edb27 1545 Pfam PF00664 ABC transporter transmembrane region 929 1127 1.3E-8 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TOT_020000655 8c808c68c6461fdb52c732f01f4edb27 1545 SUPERFAMILY SSF52540 558 740 3.16E-23 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000655 8c808c68c6461fdb52c732f01f4edb27 1545 Pfam PF00005 ABC transporter 1283 1461 8.2E-18 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000655 8c808c68c6461fdb52c732f01f4edb27 1545 Gene3D G3DSA:3.40.50.300 1248 1543 8.2E-42 T 01-11-2018 TOT_020000655 8c808c68c6461fdb52c732f01f4edb27 1545 Gene3D G3DSA:3.40.50.300 518 762 4.6E-35 T 01-11-2018 TOT_020000655 8c808c68c6461fdb52c732f01f4edb27 1545 SUPERFAMILY SSF90123 853 1127 4.84E-17 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000891 523a14bbb8e98b741231d77e4f1fc0ce 514 Pfam PF00083 Sugar (and other) transporter 57 497 3.9E-50 T 01-11-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 TOT_020000891 523a14bbb8e98b741231d77e4f1fc0ce 514 SUPERFAMILY SSF103473 17 497 1.83E-34 T 01-11-2018 IPR036259 MFS transporter superfamily TOT_020000948 c1d9f82216bf1b6d7f7c5a55c9a3203e 926 PIRSF PIRSF037016 212 559 8.5E-50 T 01-11-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOT_020000948 c1d9f82216bf1b6d7f7c5a55c9a3203e 926 PIRSF PIRSF037016 2 179 7.0E-7 T 01-11-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOT_020000948 c1d9f82216bf1b6d7f7c5a55c9a3203e 926 PIRSF PIRSF037016 620 925 2.4E-52 T 01-11-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOT_020000948 c1d9f82216bf1b6d7f7c5a55c9a3203e 926 SUPERFAMILY SSF55120 31 917 2.01E-78 T 01-11-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOT_020000948 c1d9f82216bf1b6d7f7c5a55c9a3203e 926 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 352 531 1.9E-32 T 01-11-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOT_020000948 c1d9f82216bf1b6d7f7c5a55c9a3203e 926 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 644 849 7.4E-24 T 01-11-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOT_020000948 c1d9f82216bf1b6d7f7c5a55c9a3203e 926 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 406 419 - T 01-11-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 TOT_020000948 c1d9f82216bf1b6d7f7c5a55c9a3203e 926 Gene3D G3DSA:3.30.2350.20 339 518 1.8E-40 T 01-11-2018 TOT_020000948 c1d9f82216bf1b6d7f7c5a55c9a3203e 926 Gene3D G3DSA:3.30.2350.20 672 861 7.4E-18 T 01-11-2018 TOT_020000504 cd04114399c70dde9310f49877964ded 173 SUPERFAMILY SSF53756 11 114 3.53E-9 T 01-11-2018 TOT_020000504 cd04114399c70dde9310f49877964ded 173 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 12 115 3.2E-18 T 01-11-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 TOT_020000504 cd04114399c70dde9310f49877964ded 173 Gene3D G3DSA:3.40.50.2000 7 143 4.4E-25 T 01-11-2018 TOT_010000955 818bbdea0dc256db39472c04d1a689bb 400 Gene3D G3DSA:3.40.50.1000 195 373 6.7E-40 T 01-11-2018 IPR023214 HAD superfamily TOT_010000955 818bbdea0dc256db39472c04d1a689bb 400 SMART SM00577 209 335 8.1E-19 T 01-11-2018 IPR004274 FCP1 homology domain TOT_010000955 818bbdea0dc256db39472c04d1a689bb 400 SUPERFAMILY SSF56784 207 358 2.71E-33 T 01-11-2018 IPR036412 HAD-like superfamily TOT_010000955 818bbdea0dc256db39472c04d1a689bb 400 Pfam PF03031 NLI interacting factor-like phosphatase 212 354 8.5E-33 T 01-11-2018 IPR004274 FCP1 homology domain TOT_010001016 fcdefe66c104f80984ac18dadf339e97 131 SUPERFAMILY SSF57829 76 129 6.23E-17 T 01-11-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TOT_010001016 fcdefe66c104f80984ac18dadf339e97 131 SMART SM01377 77 128 2.1E-30 T 01-11-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TOT_010001016 fcdefe66c104f80984ac18dadf339e97 131 Pfam PF01020 Ribosomal L40e family 78 127 6.4E-30 T 01-11-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TOT_010001016 fcdefe66c104f80984ac18dadf339e97 131 ProSitePatterns PS00299 Ubiquitin domain signature. 27 52 - T 01-11-2018 IPR019954 Ubiquitin conserved site TOT_010001016 fcdefe66c104f80984ac18dadf339e97 131 PRINTS PR00348 Ubiquitin signature 11 31 4.2E-39 T 01-11-2018 IPR019956 Ubiquitin TOT_010001016 fcdefe66c104f80984ac18dadf339e97 131 PRINTS PR00348 Ubiquitin signature 32 52 4.2E-39 T 01-11-2018 IPR019956 Ubiquitin TOT_010001016 fcdefe66c104f80984ac18dadf339e97 131 PRINTS PR00348 Ubiquitin signature 53 74 4.2E-39 T 01-11-2018 IPR019956 Ubiquitin TOT_010001016 fcdefe66c104f80984ac18dadf339e97 131 Gene3D G3DSA:3.10.20.90 1 77 6.0E-45 T 01-11-2018 TOT_010001016 fcdefe66c104f80984ac18dadf339e97 131 SUPERFAMILY SSF54236 1 76 3.32E-35 T 01-11-2018 IPR029071 Ubiquitin-like domain superfamily TOT_010001016 fcdefe66c104f80984ac18dadf339e97 131 Pfam PF00240 Ubiquitin family 3 74 8.9E-35 T 01-11-2018 IPR000626 Ubiquitin domain GO:0005515 TOT_010001016 fcdefe66c104f80984ac18dadf339e97 131 SMART SM00213 1 72 2.9E-36 T 01-11-2018 IPR000626 Ubiquitin domain GO:0005515 TOT_010001016 fcdefe66c104f80984ac18dadf339e97 131 Gene3D G3DSA:2.20.28.70 78 128 6.1E-30 T 01-11-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TOT_010000093 7b8f9411bf8f33d3036f94622456d594 380 Pfam PF00274 Fructose-bisphosphate aldolase class-I 6 380 6.0E-141 T 01-11-2018 IPR000741 Fructose-bisphosphate aldolase, class-I GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TOT_010000093 7b8f9411bf8f33d3036f94622456d594 380 Gene3D G3DSA:3.20.20.70 1 380 6.6E-142 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TOT_010000093 7b8f9411bf8f33d3036f94622456d594 380 SUPERFAMILY SSF51569 2 361 4.81E-116 T 01-11-2018 TOT_030000436 b60deb7613b267108124248dc4cacb9e 1136 SUPERFAMILY SSF47323 1007 1131 6.35E-14 T 01-11-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TOT_030000436 b60deb7613b267108124248dc4cacb9e 1136 Pfam PF08264 Anticodon-binding domain of tRNA 1018 1132 2.0E-9 T 01-11-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TOT_030000436 b60deb7613b267108124248dc4cacb9e 1136 Gene3D G3DSA:1.10.730.10 865 972 1.3E-22 T 01-11-2018 TOT_030000436 b60deb7613b267108124248dc4cacb9e 1136 Gene3D G3DSA:3.40.50.620 555 755 2.9E-40 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOT_030000436 b60deb7613b267108124248dc4cacb9e 1136 Gene3D G3DSA:3.40.50.620 236 438 1.6E-68 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOT_030000436 b60deb7613b267108124248dc4cacb9e 1136 Gene3D G3DSA:1.10.730.10 987 1102 8.4E-15 T 01-11-2018 TOT_030000436 b60deb7613b267108124248dc4cacb9e 1136 SUPERFAMILY SSF52374 230 934 1.27E-89 T 01-11-2018 TOT_030000436 b60deb7613b267108124248dc4cacb9e 1136 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 248 258 - T 01-11-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TOT_030000436 b60deb7613b267108124248dc4cacb9e 1136 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 231 378 9.1E-20 T 01-11-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TOT_030000436 b60deb7613b267108124248dc4cacb9e 1136 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 588 752 8.5E-6 T 01-11-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TOT_030000436 b60deb7613b267108124248dc4cacb9e 1136 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 885 923 4.0E-7 T 01-11-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TOT_030000436 b60deb7613b267108124248dc4cacb9e 1136 PRINTS PR00985 Leucyl-tRNA synthetase signature 419 438 3.9E-36 T 01-11-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TOT_030000436 b60deb7613b267108124248dc4cacb9e 1136 PRINTS PR00985 Leucyl-tRNA synthetase signature 358 374 3.9E-36 T 01-11-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TOT_030000436 b60deb7613b267108124248dc4cacb9e 1136 PRINTS PR00985 Leucyl-tRNA synthetase signature 332 349 3.9E-36 T 01-11-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TOT_030000436 b60deb7613b267108124248dc4cacb9e 1136 PRINTS PR00985 Leucyl-tRNA synthetase signature 667 685 3.9E-36 T 01-11-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TOT_030000436 b60deb7613b267108124248dc4cacb9e 1136 PRINTS PR00985 Leucyl-tRNA synthetase signature 706 728 3.9E-36 T 01-11-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TOT_030000436 b60deb7613b267108124248dc4cacb9e 1136 PRINTS PR00985 Leucyl-tRNA synthetase signature 739 749 3.9E-36 T 01-11-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TOT_030000436 b60deb7613b267108124248dc4cacb9e 1136 PRINTS PR00985 Leucyl-tRNA synthetase signature 390 403 3.9E-36 T 01-11-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TOT_020000677 ac7fdb1159c87604b2e23677a4531bdf 490 SUPERFAMILY SSF53067 171 489 4.32E-45 T 01-11-2018 TOT_020000677 ac7fdb1159c87604b2e23677a4531bdf 490 Gene3D G3DSA:3.30.420.40 163 204 9.5E-31 T 01-11-2018 TOT_020000677 ac7fdb1159c87604b2e23677a4531bdf 490 SMART SM00268 13 490 4.9E-40 T 01-11-2018 IPR004000 Actin family TOT_020000677 ac7fdb1159c87604b2e23677a4531bdf 490 Gene3D G3DSA:3.90.640.10 346 382 4.3E-33 T 01-11-2018 TOT_020000677 ac7fdb1159c87604b2e23677a4531bdf 490 Gene3D G3DSA:3.30.420.40 454 481 4.3E-33 T 01-11-2018 TOT_020000677 ac7fdb1159c87604b2e23677a4531bdf 490 Gene3D G3DSA:3.30.420.40 16 162 9.5E-31 T 01-11-2018 TOT_020000677 ac7fdb1159c87604b2e23677a4531bdf 490 Gene3D G3DSA:3.30.420.40 383 453 4.3E-33 T 01-11-2018 TOT_020000677 ac7fdb1159c87604b2e23677a4531bdf 490 Gene3D G3DSA:3.90.640.10 205 267 9.5E-31 T 01-11-2018 TOT_020000677 ac7fdb1159c87604b2e23677a4531bdf 490 Pfam PF00022 Actin 10 489 2.2E-72 T 01-11-2018 IPR004000 Actin family TOT_020000677 ac7fdb1159c87604b2e23677a4531bdf 490 SUPERFAMILY SSF53067 11 178 2.3E-20 T 01-11-2018 TOT_030000292 d43086bd54bd0872e36d6a147a8ba77b 250 Pfam PF13019 Telomere stability and silencing 85 176 7.3E-15 T 01-11-2018 IPR024974 Sde2 N-terminal domain TOT_040000157 fd612af33efaa2782776118815c44eb6 164 Pfam PF16906 Ribosomal proteins L26 eukaryotic, L24P archaeal 35 148 1.6E-35 T 01-11-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_040000157 fd612af33efaa2782776118815c44eb6 164 Pfam PF00467 KOW motif 78 109 1.8E-7 T 01-11-2018 IPR005824 KOW TOT_040000157 fd612af33efaa2782776118815c44eb6 164 SMART SM00739 75 102 2.7E-5 T 01-11-2018 IPR005824 KOW TOT_040000157 fd612af33efaa2782776118815c44eb6 164 TIGRFAM TIGR01080 rplX_A_E: ribosomal protein uL24 35 149 1.5E-45 T 01-11-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_040000157 fd612af33efaa2782776118815c44eb6 164 Gene3D G3DSA:2.30.30.30 28 164 4.2E-51 T 01-11-2018 IPR014722 Ribosomal protein L2, domain 2 TOT_040000157 fd612af33efaa2782776118815c44eb6 164 SUPERFAMILY SSF50104 35 150 6.52E-35 T 01-11-2018 IPR008991 Translation protein SH3-like domain superfamily TOT_040000178 932e2ff149636b085a90b5431d4305c7 164 SUPERFAMILY SSF57829 111 162 1.41E-17 T 01-11-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TOT_040000178 932e2ff149636b085a90b5431d4305c7 164 SUPERFAMILY SSF54236 6 68 8.01E-6 T 01-11-2018 IPR029071 Ubiquitin-like domain superfamily TOT_040000178 932e2ff149636b085a90b5431d4305c7 164 SMART SM01402 113 157 1.1E-22 T 01-11-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TOT_040000178 932e2ff149636b085a90b5431d4305c7 164 Gene3D G3DSA:2.20.25.660 90 164 1.3E-33 T 01-11-2018 IPR038582 S27a-like superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TOT_040000178 932e2ff149636b085a90b5431d4305c7 164 Pfam PF01599 Ribosomal protein S27a 113 157 1.4E-21 T 01-11-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TOT_030000539 361be115bb96d0cec3ffd25701580d4c 265 Pfam PF04385 Domain of unknown function, DUF529 46 95 6.1E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000494 69cc263e0f800c12c52288168e9dbaef 2558 Gene3D G3DSA:1.25.40.180 1066 1296 1.0E-32 T 01-11-2018 IPR016021 MIF4G-like domain superfamily TOT_020000494 69cc263e0f800c12c52288168e9dbaef 2558 Gene3D G3DSA:1.25.40.800 2348 2551 4.6E-17 T 01-11-2018 TOT_020000494 69cc263e0f800c12c52288168e9dbaef 2558 Pfam PF16415 CCR4-NOT transcription complex subunit 1 CAF1-binding domain 1109 1288 1.0E-27 T 01-11-2018 IPR032191 CCR4-NOT transcription complex subunit 1, CAF1-binding domain Reactome: R-HSA-429947|Reactome: R-HSA-6804115 TOT_020000494 69cc263e0f800c12c52288168e9dbaef 2558 Pfam PF04054 CCR4-Not complex component, Not1 2218 2552 1.9E-30 T 01-11-2018 IPR007196 CCR4-Not complex component, Not1, C-terminal Reactome: R-HSA-429947|Reactome: R-HSA-6804115 TOT_020000494 69cc263e0f800c12c52288168e9dbaef 2558 Gene3D G3DSA:1.25.40.790 2180 2347 1.5E-8 T 01-11-2018 TOT_020000494 69cc263e0f800c12c52288168e9dbaef 2558 Pfam PF12842 Domain of unknown function (DUF3819) 1427 1517 6.4E-18 T 01-11-2018 IPR024557 CCR4-Not complex, Not1 subunit, domain of unknown function DUF3819 Reactome: R-HSA-429947|Reactome: R-HSA-6804115 TOT_040000616 2988c095d86ce9fd745ec048fd3d5d0b 1517 Pfam PF00005 ABC transporter 1256 1434 1.4E-17 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_040000616 2988c095d86ce9fd745ec048fd3d5d0b 1517 SUPERFAMILY SSF52540 527 721 4.16E-24 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_040000616 2988c095d86ce9fd745ec048fd3d5d0b 1517 Gene3D G3DSA:3.40.50.300 1228 1512 1.9E-40 T 01-11-2018 TOT_040000616 2988c095d86ce9fd745ec048fd3d5d0b 1517 Gene3D G3DSA:1.20.1560.10 820 1162 7.2E-12 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_040000616 2988c095d86ce9fd745ec048fd3d5d0b 1517 SUPERFAMILY SSF52540 1229 1504 2.39E-24 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_040000616 2988c095d86ce9fd745ec048fd3d5d0b 1517 SUPERFAMILY SSF90123 836 1154 1.02E-20 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_040000616 2988c095d86ce9fd745ec048fd3d5d0b 1517 SMART SM00382 1265 1489 0.55 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_040000616 2988c095d86ce9fd745ec048fd3d5d0b 1517 SMART SM00382 543 744 1.2 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_040000616 2988c095d86ce9fd745ec048fd3d5d0b 1517 ProSitePatterns PS00211 ABC transporters family signature. 646 660 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_040000616 2988c095d86ce9fd745ec048fd3d5d0b 1517 Gene3D G3DSA:3.40.50.300 490 739 3.1E-36 T 01-11-2018 TOT_040000616 2988c095d86ce9fd745ec048fd3d5d0b 1517 Pfam PF00005 ABC transporter 534 661 4.8E-13 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_040000617 c6f204002d04fbdddd141af82f92d14a 1512 Gene3D G3DSA:3.40.50.300 500 736 2.0E-35 T 01-11-2018 TOT_040000617 c6f204002d04fbdddd141af82f92d14a 1512 SUPERFAMILY SSF52540 525 704 2.42E-23 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_040000617 c6f204002d04fbdddd141af82f92d14a 1512 SUPERFAMILY SSF90123 820 1132 2.35E-19 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_040000617 c6f204002d04fbdddd141af82f92d14a 1512 Pfam PF00005 ABC transporter 532 659 4.8E-13 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_040000617 c6f204002d04fbdddd141af82f92d14a 1512 Pfam PF00664 ABC transporter transmembrane region 897 1094 7.6E-11 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TOT_040000617 c6f204002d04fbdddd141af82f92d14a 1512 Gene3D G3DSA:3.40.50.300 1221 1511 9.6E-45 T 01-11-2018 TOT_040000617 c6f204002d04fbdddd141af82f92d14a 1512 SUPERFAMILY SSF52540 1118 1501 1.09E-27 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_040000617 c6f204002d04fbdddd141af82f92d14a 1512 ProSitePatterns PS00211 ABC transporters family signature. 644 658 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_040000617 c6f204002d04fbdddd141af82f92d14a 1512 Pfam PF00005 ABC transporter 1250 1428 6.5E-19 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_040000617 c6f204002d04fbdddd141af82f92d14a 1512 Gene3D G3DSA:1.20.1560.10 822 1137 1.1E-8 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_040000617 c6f204002d04fbdddd141af82f92d14a 1512 SMART SM00382 541 739 0.66 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_040000617 c6f204002d04fbdddd141af82f92d14a 1512 SMART SM00382 1259 1493 0.028 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000214 5c06fbd30a60c4c47d7606e8f12238d6 604 SUPERFAMILY SSF103473 63 448 5.75E-8 T 01-11-2018 IPR036259 MFS transporter superfamily TOT_040000213 74e19e37449e7aa7f4e3153531264361 116 Hamap MF_01478 50S ribosomal protein L12 [rpl12]. 17 116 13.142 T 01-11-2018 IPR027534 Ribosomal protein L12 family GO:0003735|GO:0005622|GO:0005840|GO:0006414 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_040000213 74e19e37449e7aa7f4e3153531264361 116 Pfam PF00428 60s Acidic ribosomal protein 33 115 8.0E-22 T 01-11-2018 TOT_040000213 74e19e37449e7aa7f4e3153531264361 116 Gene3D G3DSA:1.10.10.1410 13 74 1.0E-20 T 01-11-2018 IPR038716 Ribosomal protein P1/P2, N-terminal domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_020000153 dd9a6a8209db736c40146979e82c15a0 1472 Gene3D G3DSA:3.30.110.100 589 701 2.8E-16 T 01-11-2018 TOT_020000153 dd9a6a8209db736c40146979e82c15a0 1472 Pfam PF03159 XRN 5'-3' exonuclease N-terminus 1 281 3.9E-84 T 01-11-2018 IPR004859 Putative 5-3 exonuclease GO:0003676|GO:0004527 TOT_020000153 dd9a6a8209db736c40146979e82c15a0 1472 Gene3D G3DSA:3.40.50.12390 172 351 5.8E-48 T 01-11-2018 TOT_020000153 dd9a6a8209db736c40146979e82c15a0 1472 Gene3D G3DSA:3.40.50.12390 1 152 4.9E-31 T 01-11-2018 TOT_030000644 b03b1704983f530ebdc1e40b218cc67b 1535 Gene3D G3DSA:1.20.1560.10 818 1154 4.7E-11 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_030000644 b03b1704983f530ebdc1e40b218cc67b 1535 Pfam PF00005 ABC transporter 1252 1451 1.1E-17 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_030000644 b03b1704983f530ebdc1e40b218cc67b 1535 Gene3D G3DSA:3.40.50.300 485 778 2.0E-33 T 01-11-2018 TOT_030000644 b03b1704983f530ebdc1e40b218cc67b 1535 SUPERFAMILY SSF90123 905 1150 1.7E-20 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_030000644 b03b1704983f530ebdc1e40b218cc67b 1535 ProSitePatterns PS00211 ABC transporters family signature. 643 657 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_030000644 b03b1704983f530ebdc1e40b218cc67b 1535 SUPERFAMILY SSF52540 1215 1521 5.92E-24 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_030000644 b03b1704983f530ebdc1e40b218cc67b 1535 SUPERFAMILY SSF52540 500 718 4.82E-22 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_030000644 b03b1704983f530ebdc1e40b218cc67b 1535 Pfam PF00005 ABC transporter 531 657 9.1E-12 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_030000644 b03b1704983f530ebdc1e40b218cc67b 1535 SMART SM00382 540 740 1.2 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_030000644 b03b1704983f530ebdc1e40b218cc67b 1535 SMART SM00382 1261 1508 0.39 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_040000017 4c9affb2bf97cb7e2afc65a7ea70fd7e 1499 Gene3D G3DSA:3.40.50.300 473 713 1.8E-33 T 01-11-2018 TOT_040000017 4c9affb2bf97cb7e2afc65a7ea70fd7e 1499 Pfam PF00005 ABC transporter 521 647 1.9E-11 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_040000017 4c9affb2bf97cb7e2afc65a7ea70fd7e 1499 SUPERFAMILY SSF52540 514 707 2.23E-22 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_040000017 4c9affb2bf97cb7e2afc65a7ea70fd7e 1499 Pfam PF00005 ABC transporter 1240 1417 2.9E-18 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_040000017 4c9affb2bf97cb7e2afc65a7ea70fd7e 1499 SUPERFAMILY SSF52540 1217 1482 1.89E-25 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_040000017 4c9affb2bf97cb7e2afc65a7ea70fd7e 1499 Gene3D G3DSA:1.20.1560.10 800 1145 3.3E-10 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_040000017 4c9affb2bf97cb7e2afc65a7ea70fd7e 1499 ProSitePatterns PS00211 ABC transporters family signature. 633 647 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_040000017 4c9affb2bf97cb7e2afc65a7ea70fd7e 1499 Gene3D G3DSA:3.40.50.300 1212 1498 1.6E-42 T 01-11-2018 TOT_040000017 4c9affb2bf97cb7e2afc65a7ea70fd7e 1499 SUPERFAMILY SSF90123 816 1139 3.53E-22 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_040000017 4c9affb2bf97cb7e2afc65a7ea70fd7e 1499 SMART SM00382 1249 1418 0.28 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_040000017 4c9affb2bf97cb7e2afc65a7ea70fd7e 1499 SMART SM00382 530 730 0.58 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_010000965 e2d6c227c49d724ada855533f33f0e46 758 SUPERFAMILY SSF46565 385 488 2.36E-5 T 01-11-2018 IPR036869 Chaperone J-domain superfamily TOT_030000513 145eee66fdd16744d52097d1d3d81d35 476 Gene3D G3DSA:1.20.1250.20 264 468 4.8E-11 T 01-11-2018 TOT_030000513 145eee66fdd16744d52097d1d3d81d35 476 Gene3D G3DSA:1.20.1250.20 1 144 1.9E-17 T 01-11-2018 TOT_030000513 145eee66fdd16744d52097d1d3d81d35 476 SUPERFAMILY SSF103473 2 465 5.1E-37 T 01-11-2018 IPR036259 MFS transporter superfamily TOT_030000513 145eee66fdd16744d52097d1d3d81d35 476 Pfam PF07690 Major Facilitator Superfamily 2 331 1.4E-19 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOT_010000685 b584d208105cb573c113e92e4a3f3891 448 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 61 76 - T 01-11-2018 IPR031157 Tr-type G domain, conserved site TOT_010000685 b584d208105cb573c113e92e4a3f3891 448 Gene3D G3DSA:3.40.50.300 1 223 1.7E-90 T 01-11-2018 TOT_010000685 b584d208105cb573c113e92e4a3f3891 448 Pfam PF00009 Elongation factor Tu GTP binding domain 5 200 1.9E-53 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOT_010000685 b584d208105cb573c113e92e4a3f3891 448 SUPERFAMILY SSF50447 224 319 8.84E-26 T 01-11-2018 IPR009000 Translation protein, beta-barrel domain superfamily TOT_010000685 b584d208105cb573c113e92e4a3f3891 448 SUPERFAMILY SSF52540 3 247 1.15E-79 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010000685 b584d208105cb573c113e92e4a3f3891 448 Pfam PF03144 Elongation factor Tu domain 2 246 311 8.0E-12 T 01-11-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TOT_010000685 b584d208105cb573c113e92e4a3f3891 448 Hamap MF_00118_A Elongation factor Tu [tuf]. 2 430 51.548 T 01-11-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 TOT_010000685 b584d208105cb573c113e92e4a3f3891 448 Gene3D G3DSA:2.40.30.10 321 428 1.3E-48 T 01-11-2018 TOT_010000685 b584d208105cb573c113e92e4a3f3891 448 Gene3D G3DSA:2.40.30.10 226 318 4.1E-38 T 01-11-2018 TOT_010000685 b584d208105cb573c113e92e4a3f3891 448 Pfam PF03143 Elongation factor Tu C-terminal domain 320 427 6.9E-39 T 01-11-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal TOT_010000685 b584d208105cb573c113e92e4a3f3891 448 PRINTS PR00315 GTP-binding elongation factor signature 148 157 2.7E-22 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOT_010000685 b584d208105cb573c113e92e4a3f3891 448 PRINTS PR00315 GTP-binding elongation factor signature 9 22 2.7E-22 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOT_010000685 b584d208105cb573c113e92e4a3f3891 448 PRINTS PR00315 GTP-binding elongation factor signature 68 76 2.7E-22 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOT_010000685 b584d208105cb573c113e92e4a3f3891 448 PRINTS PR00315 GTP-binding elongation factor signature 88 98 2.7E-22 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOT_010000685 b584d208105cb573c113e92e4a3f3891 448 PRINTS PR00315 GTP-binding elongation factor signature 104 115 2.7E-22 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOT_010000685 b584d208105cb573c113e92e4a3f3891 448 TIGRFAM TIGR00483 EF-1_alpha: translation elongation factor EF-1, subunit alpha 1 431 3.2E-209 T 01-11-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 TOT_010000685 b584d208105cb573c113e92e4a3f3891 448 SUPERFAMILY SSF50465 325 427 1.87E-41 T 01-11-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TOT_040000953 5331355265642bdb75b9b41f50e225b4 85 Pfam PF03143 Elongation factor Tu C-terminal domain 2 81 6.2E-18 T 01-11-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal TOT_040000953 5331355265642bdb75b9b41f50e225b4 85 Gene3D G3DSA:2.40.30.10 1 82 4.9E-23 T 01-11-2018 TOT_040000953 5331355265642bdb75b9b41f50e225b4 85 SUPERFAMILY SSF50465 1 82 1.91E-19 T 01-11-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TOT_010000107 779f4a7214dd80c9cbbbaa8defe4ffc4 116 Gene3D G3DSA:3.10.50.40 1 116 7.8E-39 T 01-11-2018 TOT_010000107 779f4a7214dd80c9cbbbaa8defe4ffc4 116 SUPERFAMILY SSF54534 2 114 7.2E-26 T 01-11-2018 TOT_010000107 779f4a7214dd80c9cbbbaa8defe4ffc4 116 Pfam PF00639 PPIC-type PPIASE domain 8 115 1.4E-20 T 01-11-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 TOT_040000950 e7d0aaee51fc0d365cff9d6456be5e39 409 Pfam PF04857 CAF1 family ribonuclease 10 124 8.3E-10 T 01-11-2018 IPR006941 Ribonuclease CAF1 TOT_040000950 e7d0aaee51fc0d365cff9d6456be5e39 409 SUPERFAMILY SSF53098 7 257 4.77E-84 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily TOT_040000950 e7d0aaee51fc0d365cff9d6456be5e39 409 Gene3D G3DSA:3.30.420.10 1 260 5.3E-110 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TOT_040000950 e7d0aaee51fc0d365cff9d6456be5e39 409 Pfam PF04857 CAF1 family ribonuclease 142 230 6.8E-8 T 01-11-2018 IPR006941 Ribonuclease CAF1 TOT_020000963 ebe3d215961f006d933bf5c6d17dc778 615 Pfam PF12763 Cytoskeletal-regulatory complex EF hand 7 76 1.6E-9 T 01-11-2018 IPR000261 EH domain GO:0005515 TOT_020000963 ebe3d215961f006d933bf5c6d17dc778 615 Pfam PF12763 Cytoskeletal-regulatory complex EF hand 136 215 6.3E-9 T 01-11-2018 IPR000261 EH domain GO:0005515 TOT_020000963 ebe3d215961f006d933bf5c6d17dc778 615 Gene3D G3DSA:1.10.238.10 115 219 2.1E-15 T 01-11-2018 TOT_020000963 ebe3d215961f006d933bf5c6d17dc778 615 SMART SM00054 48 76 2.5 T 01-11-2018 IPR002048 EF-hand domain GO:0005509 TOT_020000963 ebe3d215961f006d933bf5c6d17dc778 615 SMART SM00054 170 198 0.64 T 01-11-2018 IPR002048 EF-hand domain GO:0005509 TOT_020000963 ebe3d215961f006d933bf5c6d17dc778 615 ProSitePatterns PS00018 EF-hand calcium-binding domain. 179 191 - T 01-11-2018 IPR018247 EF-Hand 1, calcium-binding site TOT_020000963 ebe3d215961f006d933bf5c6d17dc778 615 SUPERFAMILY SSF47473 6 201 7.8E-22 T 01-11-2018 IPR011992 EF-hand domain pair TOT_020000963 ebe3d215961f006d933bf5c6d17dc778 615 Gene3D G3DSA:1.10.238.10 5 89 5.0E-18 T 01-11-2018 TOT_020000963 ebe3d215961f006d933bf5c6d17dc778 615 SMART SM00027 125 221 4.8E-13 T 01-11-2018 IPR000261 EH domain GO:0005515 TOT_020000963 ebe3d215961f006d933bf5c6d17dc778 615 SMART SM00027 4 92 1.5E-7 T 01-11-2018 IPR000261 EH domain GO:0005515 TOT_040000139 a9136e05d18bd28ab2b8bda3bd2a95c5 401 Pfam PF00847 AP2 domain 212 262 8.8E-18 T 01-11-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 TOT_040000139 a9136e05d18bd28ab2b8bda3bd2a95c5 401 Pfam PF14733 AP2-coincident C-terminal 308 398 2.7E-22 T 01-11-2018 IPR028078 AP2-coincident, C-terminal domain TOT_030000011 1253efc23967f013439f264cda26f500 1518 Gene3D G3DSA:3.40.50.300 482 771 4.3E-33 T 01-11-2018 TOT_030000011 1253efc23967f013439f264cda26f500 1518 Pfam PF00005 ABC transporter 531 657 5.1E-12 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_030000011 1253efc23967f013439f264cda26f500 1518 Gene3D G3DSA:1.20.1560.10 813 1155 1.1E-9 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_030000011 1253efc23967f013439f264cda26f500 1518 SUPERFAMILY SSF90123 831 1152 1.7E-22 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_030000011 1253efc23967f013439f264cda26f500 1518 SUPERFAMILY SSF52540 1167 1504 6.69E-24 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_030000011 1253efc23967f013439f264cda26f500 1518 SUPERFAMILY SSF52540 525 706 1.52E-21 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_030000011 1253efc23967f013439f264cda26f500 1518 ProSitePatterns PS00211 ABC transporters family signature. 643 657 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_030000011 1253efc23967f013439f264cda26f500 1518 Pfam PF00005 ABC transporter 1251 1436 2.4E-17 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_030000011 1253efc23967f013439f264cda26f500 1518 SUPERFAMILY SSF90123 115 464 3.63E-5 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_010000611 1954c7e1af7b0750c845c5e64ebd7bdf 1311 SUPERFAMILY SSF90123 626 945 9.29E-19 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_010000611 1954c7e1af7b0750c845c5e64ebd7bdf 1311 SUPERFAMILY SSF52540 1026 1291 5.22E-24 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010000611 1954c7e1af7b0750c845c5e64ebd7bdf 1311 SUPERFAMILY SSF52540 320 513 1.72E-23 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010000611 1954c7e1af7b0750c845c5e64ebd7bdf 1311 Pfam PF00005 ABC transporter 1048 1228 2.4E-17 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_010000611 1954c7e1af7b0750c845c5e64ebd7bdf 1311 Gene3D G3DSA:3.40.50.300 290 553 3.6E-34 T 01-11-2018 TOT_010000611 1954c7e1af7b0750c845c5e64ebd7bdf 1311 Gene3D G3DSA:3.40.50.300 1017 1308 1.7E-40 T 01-11-2018 TOT_010000611 1954c7e1af7b0750c845c5e64ebd7bdf 1311 SMART SM00382 1057 1300 0.47 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_010000611 1954c7e1af7b0750c845c5e64ebd7bdf 1311 SMART SM00382 336 539 0.69 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_010000611 1954c7e1af7b0750c845c5e64ebd7bdf 1311 Pfam PF00005 ABC transporter 327 454 8.8E-13 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_010000611 1954c7e1af7b0750c845c5e64ebd7bdf 1311 ProSitePatterns PS00211 ABC transporters family signature. 439 453 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_030000067 be5d18523def3c58f6e0a9f0a4d021bc 682 SUPERFAMILY SSF48371 11 590 7.68E-6 T 01-11-2018 IPR016024 Armadillo-type fold TOT_020000241 5c174cc56c31aa99485d65d59934f898 528 SUPERFAMILY SSF57903 11 65 2.02E-5 T 01-11-2018 IPR011011 Zinc finger, FYVE/PHD-type TOT_020000241 5c174cc56c31aa99485d65d59934f898 528 Pfam PF02891 MIZ/SP-RING zinc finger 236 285 1.6E-18 T 01-11-2018 IPR004181 Zinc finger, MIZ-type GO:0008270 TOT_020000241 5c174cc56c31aa99485d65d59934f898 528 Gene3D G3DSA:3.30.40.10 188 321 5.0E-26 T 01-11-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type TOT_040000192 3354eb2b0105b3b292b2a2c8201bd5f0 1117 Pfam PF04096 Nucleoporin autopeptidase 958 1089 1.2E-27 T 01-11-2018 IPR007230 Peptidase S59, nucleoporin GO:0005643|GO:0006913|GO:0017056 Reactome: R-HSA-1169408|Reactome: R-HSA-141444|Reactome: R-HSA-159227|Reactome: R-HSA-159230|Reactome: R-HSA-159231|Reactome: R-HSA-159236|Reactome: R-HSA-165054|Reactome: R-HSA-168271|Reactome: R-HSA-168276|Reactome: R-HSA-168325|Reactome: R-HSA-168333|Reactome: R-HSA-170822|Reactome: R-HSA-180746|Reactome: R-HSA-180910|Reactome: R-HSA-191859|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3108214|Reactome: R-HSA-3232142|Reactome: R-HSA-3301854|Reactome: R-HSA-3371453|Reactome: R-HSA-4085377|Reactome: R-HSA-4551638|Reactome: R-HSA-4570464|Reactome: R-HSA-4615885|Reactome: R-HSA-5578749|Reactome: R-HSA-5663220|Reactome: R-HSA-6784531|Reactome: R-HSA-68877 TOT_040000192 3354eb2b0105b3b292b2a2c8201bd5f0 1117 Gene3D G3DSA:3.30.1610.10 947 1091 1.8E-31 T 01-11-2018 IPR036903 Peptidase S59, nucleoporin superfamily Reactome: R-HSA-1169408|Reactome: R-HSA-141444|Reactome: R-HSA-159227|Reactome: R-HSA-159230|Reactome: R-HSA-159231|Reactome: R-HSA-159236|Reactome: R-HSA-165054|Reactome: R-HSA-168271|Reactome: R-HSA-168276|Reactome: R-HSA-168325|Reactome: R-HSA-168333|Reactome: R-HSA-170822|Reactome: R-HSA-180746|Reactome: R-HSA-180910|Reactome: R-HSA-191859|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3108214|Reactome: R-HSA-3232142|Reactome: R-HSA-3301854|Reactome: R-HSA-3371453|Reactome: R-HSA-4085377|Reactome: R-HSA-4551638|Reactome: R-HSA-4570464|Reactome: R-HSA-4615885|Reactome: R-HSA-5578749|Reactome: R-HSA-5663220|Reactome: R-HSA-6784531|Reactome: R-HSA-68877 TOT_040000192 3354eb2b0105b3b292b2a2c8201bd5f0 1117 SUPERFAMILY SSF82215 949 1091 5.1E-34 T 01-11-2018 IPR036903 Peptidase S59, nucleoporin superfamily Reactome: R-HSA-1169408|Reactome: R-HSA-141444|Reactome: R-HSA-159227|Reactome: R-HSA-159230|Reactome: R-HSA-159231|Reactome: R-HSA-159236|Reactome: R-HSA-165054|Reactome: R-HSA-168271|Reactome: R-HSA-168276|Reactome: R-HSA-168325|Reactome: R-HSA-168333|Reactome: R-HSA-170822|Reactome: R-HSA-180746|Reactome: R-HSA-180910|Reactome: R-HSA-191859|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3108214|Reactome: R-HSA-3232142|Reactome: R-HSA-3301854|Reactome: R-HSA-3371453|Reactome: R-HSA-4085377|Reactome: R-HSA-4551638|Reactome: R-HSA-4570464|Reactome: R-HSA-4615885|Reactome: R-HSA-5578749|Reactome: R-HSA-5663220|Reactome: R-HSA-6784531|Reactome: R-HSA-68877 TOT_020000529 8226df92b72d30d5cf8c237496e2a7c2 222 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 109 177 1.2E-17 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_020000529 8226df92b72d30d5cf8c237496e2a7c2 222 Pfam PF12220 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal 6 89 6.0E-19 T 01-11-2018 IPR022023 U1 small nuclear ribonucleoprotein of 70kDa N-terminal Reactome: R-HSA-72163 TOT_020000529 8226df92b72d30d5cf8c237496e2a7c2 222 SUPERFAMILY SSF54928 103 205 3.09E-27 T 01-11-2018 IPR035979 RNA-binding domain superfamily GO:0003676 TOT_020000529 8226df92b72d30d5cf8c237496e2a7c2 222 Gene3D G3DSA:3.30.70.330 101 208 1.4E-30 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_020000529 8226df92b72d30d5cf8c237496e2a7c2 222 SMART SM00360 108 180 1.9E-23 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_020000122 ae498a6ac775f12458c52a07c6a355c6 699 Pfam PF00224 Pyruvate kinase, barrel domain 120 351 2.4E-36 T 01-11-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TOT_020000122 ae498a6ac775f12458c52a07c6a355c6 699 Pfam PF00224 Pyruvate kinase, barrel domain 408 536 2.0E-49 T 01-11-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TOT_020000122 ae498a6ac775f12458c52a07c6a355c6 699 SUPERFAMILY SSF51621 116 541 2.83E-75 T 01-11-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TOT_020000122 ae498a6ac775f12458c52a07c6a355c6 699 SUPERFAMILY SSF52935 522 673 5.31E-9 T 01-11-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TOT_020000122 ae498a6ac775f12458c52a07c6a355c6 699 Gene3D G3DSA:3.40.1380.20 581 675 1.1E-7 T 01-11-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TOT_020000122 ae498a6ac775f12458c52a07c6a355c6 699 Gene3D G3DSA:2.40.33.10 217 308 5.0E-21 T 01-11-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TOT_020000122 ae498a6ac775f12458c52a07c6a355c6 699 SUPERFAMILY SSF50800 218 308 3.31E-18 T 01-11-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily TOT_020000965 752e5bb12f0851c12c8b32ad0e779e1c 292 Gene3D G3DSA:1.10.3580.10 158 292 2.0E-16 T 01-11-2018 IPR023335 ATP12 orthogonal Bundle domain superfamily TOT_020000965 752e5bb12f0851c12c8b32ad0e779e1c 292 SUPERFAMILY SSF160909 45 289 8.37E-38 T 01-11-2018 TOT_020000965 752e5bb12f0851c12c8b32ad0e779e1c 292 Pfam PF07542 ATP12 chaperone protein 50 137 5.2E-9 T 01-11-2018 IPR011419 ATP12, ATP synthase F1-assembly protein GO:0043461 TOT_040000275 153e8a935c10ef489d8fb0245fce7960 1515 SMART SM00382 1266 1489 5.1E-4 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_040000275 153e8a935c10ef489d8fb0245fce7960 1515 SMART SM00382 546 746 0.42 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_040000275 153e8a935c10ef489d8fb0245fce7960 1515 SUPERFAMILY SSF90123 127 471 6.99E-7 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_040000275 153e8a935c10ef489d8fb0245fce7960 1515 Pfam PF00005 ABC transporter 537 664 3.6E-12 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_040000275 153e8a935c10ef489d8fb0245fce7960 1515 ProSitePatterns PS00211 ABC transporters family signature. 649 663 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_040000275 153e8a935c10ef489d8fb0245fce7960 1515 SUPERFAMILY SSF90123 835 1154 1.44E-16 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_040000275 153e8a935c10ef489d8fb0245fce7960 1515 SUPERFAMILY SSF52540 1243 1495 1.7E-27 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_040000275 153e8a935c10ef489d8fb0245fce7960 1515 Gene3D G3DSA:3.40.50.300 490 776 1.6E-35 T 01-11-2018 TOT_040000275 153e8a935c10ef489d8fb0245fce7960 1515 Pfam PF00005 ABC transporter 1257 1434 7.8E-18 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_040000275 153e8a935c10ef489d8fb0245fce7960 1515 SUPERFAMILY SSF52540 528 725 2.57E-24 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_040000275 153e8a935c10ef489d8fb0245fce7960 1515 Gene3D G3DSA:3.40.50.300 1226 1510 4.6E-43 T 01-11-2018 TOT_040000678 bb78b96dd2f2aa76385bfb4c35b2f5af 766 SUPERFAMILY SSF50998 81 684 5.1E-14 T 01-11-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TOT_010000356 aff2f67ba7a54cfa91b02adc709905de 1030 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 597 690 8.6E-23 T 01-11-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold TOT_010000356 aff2f67ba7a54cfa91b02adc709905de 1030 Gene3D G3DSA:1.10.1740.60 349 432 5.0E-32 T 01-11-2018 TOT_010000356 aff2f67ba7a54cfa91b02adc709905de 1030 SUPERFAMILY SSF55486 356 603 9.16E-71 T 01-11-2018 TOT_010000356 aff2f67ba7a54cfa91b02adc709905de 1030 Gene3D G3DSA:2.60.40.1840 597 690 1.6E-24 T 01-11-2018 IPR038438 Alanyl aminopeptidase, Ig-like domain superfamily TOT_010000356 aff2f67ba7a54cfa91b02adc709905de 1030 Pfam PF01433 Peptidase family M1 domain 361 592 2.3E-54 T 01-11-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TOT_010000356 aff2f67ba7a54cfa91b02adc709905de 1030 Gene3D G3DSA:1.10.390.10 433 596 6.9E-63 T 01-11-2018 IPR027268 Peptidase M4/M1, CTD superfamily TOT_010000356 aff2f67ba7a54cfa91b02adc709905de 1030 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 411 421 2.1E-10 T 01-11-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TOT_010000356 aff2f67ba7a54cfa91b02adc709905de 1030 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 329 344 2.1E-10 T 01-11-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TOT_010000356 aff2f67ba7a54cfa91b02adc709905de 1030 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 280 295 2.1E-10 T 01-11-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TOT_010000356 aff2f67ba7a54cfa91b02adc709905de 1030 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 447 462 2.1E-10 T 01-11-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TOT_010000356 aff2f67ba7a54cfa91b02adc709905de 1030 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 466 478 2.1E-10 T 01-11-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TOT_010000356 aff2f67ba7a54cfa91b02adc709905de 1030 SUPERFAMILY SSF63737 150 346 2.62E-37 T 01-11-2018 TOT_010000356 aff2f67ba7a54cfa91b02adc709905de 1030 Gene3D G3DSA:1.25.50.10 693 1028 4.7E-91 T 01-11-2018 IPR037144 Peptidase M1, alanyl aminopeptidase, C-terminal domain superfamily TOT_010000356 aff2f67ba7a54cfa91b02adc709905de 1030 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 694 1027 4.5E-84 T 01-11-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal TOT_010000356 aff2f67ba7a54cfa91b02adc709905de 1030 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 153 1026 0.0 T 01-11-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 TOT_010000356 aff2f67ba7a54cfa91b02adc709905de 1030 Gene3D G3DSA:2.60.40.1730 156 347 1.6E-68 T 01-11-2018 TOT_010000037 72b4ca34306530584ec630b9d2276a4b 487 SUPERFAMILY SSF53067 260 485 1.81E-53 T 01-11-2018 TOT_010000037 72b4ca34306530584ec630b9d2276a4b 487 PRINTS PR00475 Hexokinase family signature 235 251 8.8E-51 T 01-11-2018 TOT_010000037 72b4ca34306530584ec630b9d2276a4b 487 PRINTS PR00475 Hexokinase family signature 178 203 8.8E-51 T 01-11-2018 TOT_010000037 72b4ca34306530584ec630b9d2276a4b 487 PRINTS PR00475 Hexokinase family signature 319 341 8.8E-51 T 01-11-2018 TOT_010000037 72b4ca34306530584ec630b9d2276a4b 487 PRINTS PR00475 Hexokinase family signature 467 483 8.8E-51 T 01-11-2018 TOT_010000037 72b4ca34306530584ec630b9d2276a4b 487 PRINTS PR00475 Hexokinase family signature 262 276 8.8E-51 T 01-11-2018 TOT_010000037 72b4ca34306530584ec630b9d2276a4b 487 PRINTS PR00475 Hexokinase family signature 395 417 8.8E-51 T 01-11-2018 TOT_010000037 72b4ca34306530584ec630b9d2276a4b 487 PRINTS PR00475 Hexokinase family signature 99 115 8.8E-51 T 01-11-2018 TOT_010000037 72b4ca34306530584ec630b9d2276a4b 487 Gene3D G3DSA:3.40.367.20 38 470 3.7E-106 T 01-11-2018 TOT_010000037 72b4ca34306530584ec630b9d2276a4b 487 Pfam PF00349 Hexokinase 33 251 4.3E-50 T 01-11-2018 IPR022672 Hexokinase, N-terminal GO:0005524|GO:0005975|GO:0016773 KEGG: 00010+2.7.1.1|KEGG: 00051+2.7.1.1|KEGG: 00052+2.7.1.1|KEGG: 00500+2.7.1.1|KEGG: 00520+2.7.1.1|KEGG: 00521+2.7.1.1|KEGG: 00524+2.7.1.1|Reactome: R-HSA-70171 TOT_010000037 72b4ca34306530584ec630b9d2276a4b 487 SUPERFAMILY SSF53067 32 253 4.21E-49 T 01-11-2018 TOT_010000037 72b4ca34306530584ec630b9d2276a4b 487 Pfam PF03727 Hexokinase 261 483 2.8E-47 T 01-11-2018 IPR022673 Hexokinase, C-terminal GO:0005524|GO:0005975|GO:0016773 KEGG: 00010+2.7.1.1|KEGG: 00051+2.7.1.1|KEGG: 00052+2.7.1.1|KEGG: 00500+2.7.1.1|KEGG: 00520+2.7.1.1|KEGG: 00521+2.7.1.1|KEGG: 00524+2.7.1.1|Reactome: R-HSA-70171 TOT_010000037 72b4ca34306530584ec630b9d2276a4b 487 Gene3D G3DSA:3.30.420.40 84 480 3.7E-106 T 01-11-2018 TOT_020000882 7c6d6913f79da128c71a4fedc75dd338 1096 Pfam PF04385 Domain of unknown function, DUF529 723 780 3.2E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000551 09b9dbfefe043fecc6c751c6d1013164 570 SMART SM00220 73 566 3.1E-12 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOT_010000551 09b9dbfefe043fecc6c751c6d1013164 570 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 221 233 - T 01-11-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TOT_010000551 09b9dbfefe043fecc6c751c6d1013164 570 Gene3D G3DSA:1.10.510.10 55 249 6.5E-15 T 01-11-2018 TOT_010000551 09b9dbfefe043fecc6c751c6d1013164 570 Pfam PF00069 Protein kinase domain 446 566 8.7E-17 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOT_010000551 09b9dbfefe043fecc6c751c6d1013164 570 Pfam PF00069 Protein kinase domain 92 239 7.0E-12 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOT_010000551 09b9dbfefe043fecc6c751c6d1013164 570 Gene3D G3DSA:1.10.510.10 430 570 3.5E-23 T 01-11-2018 TOT_010000551 09b9dbfefe043fecc6c751c6d1013164 570 SUPERFAMILY SSF56112 67 568 3.71E-42 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily TOT_010000406 4a161a20b392568aea48e03c89dd03f5 630 Gene3D G3DSA:1.20.920.10 506 630 1.7E-31 T 01-11-2018 IPR036427 Bromodomain-like superfamily GO:0005515 TOT_010000406 4a161a20b392568aea48e03c89dd03f5 630 Pfam PF00583 Acetyltransferase (GNAT) family 334 418 1.9E-11 T 01-11-2018 IPR000182 GNAT domain TOT_010000406 4a161a20b392568aea48e03c89dd03f5 630 SUPERFAMILY SSF55729 316 452 2.48E-22 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase TOT_010000406 4a161a20b392568aea48e03c89dd03f5 630 Pfam PF00439 Bromodomain 536 615 1.7E-20 T 01-11-2018 IPR001487 Bromodomain GO:0005515 TOT_010000406 4a161a20b392568aea48e03c89dd03f5 630 PRINTS PR00503 Bromodomain signature 558 574 5.8E-14 T 01-11-2018 IPR001487 Bromodomain GO:0005515 TOT_010000406 4a161a20b392568aea48e03c89dd03f5 630 PRINTS PR00503 Bromodomain signature 574 592 5.8E-14 T 01-11-2018 IPR001487 Bromodomain GO:0005515 TOT_010000406 4a161a20b392568aea48e03c89dd03f5 630 PRINTS PR00503 Bromodomain signature 592 611 5.8E-14 T 01-11-2018 IPR001487 Bromodomain GO:0005515 TOT_010000406 4a161a20b392568aea48e03c89dd03f5 630 PRINTS PR00503 Bromodomain signature 544 557 5.8E-14 T 01-11-2018 IPR001487 Bromodomain GO:0005515 TOT_010000406 4a161a20b392568aea48e03c89dd03f5 630 SMART SM00297 522 630 1.2E-28 T 01-11-2018 IPR001487 Bromodomain GO:0005515 TOT_010000406 4a161a20b392568aea48e03c89dd03f5 630 SUPERFAMILY SSF47370 518 628 6.54E-33 T 01-11-2018 IPR036427 Bromodomain-like superfamily GO:0005515 TOT_010000406 4a161a20b392568aea48e03c89dd03f5 630 Gene3D G3DSA:3.40.630.30 293 454 2.6E-71 T 01-11-2018 TOT_040000579 b3c8cf797c8b105d714e1023d3b965c0 123 SUPERFAMILY SSF50193 5 116 3.92E-29 T 01-11-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 TOT_040000579 b3c8cf797c8b105d714e1023d3b965c0 123 ProSitePatterns PS00049 Ribosomal protein L14 signature. 66 92 - T 01-11-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_040000579 b3c8cf797c8b105d714e1023d3b965c0 123 Pfam PF00238 Ribosomal protein L14p/L23e 10 114 4.0E-23 T 01-11-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TOT_040000579 b3c8cf797c8b105d714e1023d3b965c0 123 SMART SM01374 9 123 5.8E-31 T 01-11-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TOT_040000579 b3c8cf797c8b105d714e1023d3b965c0 123 Gene3D G3DSA:2.40.150.20 2 122 1.3E-29 T 01-11-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 TOT_040000579 b3c8cf797c8b105d714e1023d3b965c0 123 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 9 123 17.965 T 01-11-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TOT_010000085 ee05a2cc6308fc3fddb286ec0c494fcb 269 PRINTS PR01166 Cytochrome c oxidase subunit II signature 222 242 5.0E-10 T 01-11-2018 TOT_010000085 ee05a2cc6308fc3fddb286ec0c494fcb 269 PRINTS PR01166 Cytochrome c oxidase subunit II signature 244 263 5.0E-10 T 01-11-2018 TOT_010000085 ee05a2cc6308fc3fddb286ec0c494fcb 269 Gene3D G3DSA:2.60.40.420 244 264 5.0E-8 T 01-11-2018 IPR008972 Cupredoxin TOT_010000085 ee05a2cc6308fc3fddb286ec0c494fcb 269 Gene3D G3DSA:1.10.287.90 207 243 5.0E-8 T 01-11-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TOT_010001316 ced9eb159c310f52cad56ab7e293a8a5 1096 SUPERFAMILY SSF110942 731 813 6.54E-15 T 01-11-2018 IPR037196 HSP90, C-terminal domain TOT_010001316 ced9eb159c310f52cad56ab7e293a8a5 1096 SUPERFAMILY SSF54211 582 706 2.43E-27 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TOT_010001316 ced9eb159c310f52cad56ab7e293a8a5 1096 Pfam PF00183 Hsp90 protein 585 815 1.9E-63 T 01-11-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 TOT_010001316 ced9eb159c310f52cad56ab7e293a8a5 1096 Pfam PF00183 Hsp90 protein 349 525 4.1E-51 T 01-11-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 TOT_010001316 ced9eb159c310f52cad56ab7e293a8a5 1096 Gene3D G3DSA:3.40.50.12450 591 705 8.2E-34 T 01-11-2018 TOT_010001316 ced9eb159c310f52cad56ab7e293a8a5 1096 SUPERFAMILY SSF54211 361 513 2.05E-45 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TOT_010001316 ced9eb159c310f52cad56ab7e293a8a5 1096 Gene3D G3DSA:3.30.230.80 362 528 4.7E-48 T 01-11-2018 TOT_010001316 ced9eb159c310f52cad56ab7e293a8a5 1096 PRINTS PR00775 90kDa heat shock protein signature 139 159 4.8E-61 T 01-11-2018 IPR020575 Heat shock protein Hsp90, N-terminal TOT_010001316 ced9eb159c310f52cad56ab7e293a8a5 1096 PRINTS PR00775 90kDa heat shock protein signature 160 182 4.8E-61 T 01-11-2018 IPR020575 Heat shock protein Hsp90, N-terminal TOT_010001316 ced9eb159c310f52cad56ab7e293a8a5 1096 PRINTS PR00775 90kDa heat shock protein signature 253 275 4.8E-61 T 01-11-2018 IPR020575 Heat shock protein Hsp90, N-terminal TOT_010001316 ced9eb159c310f52cad56ab7e293a8a5 1096 PRINTS PR00775 90kDa heat shock protein signature 227 244 4.8E-61 T 01-11-2018 IPR020575 Heat shock protein Hsp90, N-terminal TOT_010001316 ced9eb159c310f52cad56ab7e293a8a5 1096 PRINTS PR00775 90kDa heat shock protein signature 305 322 4.8E-61 T 01-11-2018 IPR020575 Heat shock protein Hsp90, N-terminal TOT_010001316 ced9eb159c310f52cad56ab7e293a8a5 1096 PRINTS PR00775 90kDa heat shock protein signature 323 341 4.8E-61 T 01-11-2018 IPR020575 Heat shock protein Hsp90, N-terminal TOT_010001316 ced9eb159c310f52cad56ab7e293a8a5 1096 PRINTS PR00775 90kDa heat shock protein signature 209 226 4.8E-61 T 01-11-2018 IPR020575 Heat shock protein Hsp90, N-terminal TOT_010001316 ced9eb159c310f52cad56ab7e293a8a5 1096 Gene3D G3DSA:3.30.565.10 124 356 5.2E-74 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TOT_010001316 ced9eb159c310f52cad56ab7e293a8a5 1096 SUPERFAMILY SSF55874 138 346 1.47E-58 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TOT_010001316 ced9eb159c310f52cad56ab7e293a8a5 1096 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 163 315 2.8E-6 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase TOT_010001316 ced9eb159c310f52cad56ab7e293a8a5 1096 Hamap MF_00505 Chaperone protein HtpG [htpG]. 136 935 22.632 T 01-11-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 TOT_010001316 ced9eb159c310f52cad56ab7e293a8a5 1096 Gene3D G3DSA:1.20.120.790 706 848 2.3E-24 T 01-11-2018 IPR037196 HSP90, C-terminal domain TOT_040000244 f153869086d4cd57e9bd0892d53d54e4 521 SMART SM00320 198 237 3.5E-7 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_040000244 f153869086d4cd57e9bd0892d53d54e4 521 SMART SM00320 324 363 2.1E-7 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_040000244 f153869086d4cd57e9bd0892d53d54e4 521 SMART SM00320 240 279 2.5E-7 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_040000244 f153869086d4cd57e9bd0892d53d54e4 521 SMART SM00320 460 498 0.14 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_040000244 f153869086d4cd57e9bd0892d53d54e4 521 SMART SM00320 366 404 3.8E-4 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_040000244 f153869086d4cd57e9bd0892d53d54e4 521 SMART SM00320 282 321 2.2E-7 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_040000244 f153869086d4cd57e9bd0892d53d54e4 521 SMART SM00320 407 448 4.2E-6 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_040000244 f153869086d4cd57e9bd0892d53d54e4 521 PRINTS PR00320 G protein beta WD-40 repeat signature 224 238 2.8E-8 T 01-11-2018 IPR020472 G-protein beta WD-40 repeat TOT_040000244 f153869086d4cd57e9bd0892d53d54e4 521 PRINTS PR00320 G protein beta WD-40 repeat signature 350 364 2.8E-8 T 01-11-2018 IPR020472 G-protein beta WD-40 repeat TOT_040000244 f153869086d4cd57e9bd0892d53d54e4 521 PRINTS PR00320 G protein beta WD-40 repeat signature 266 280 2.8E-8 T 01-11-2018 IPR020472 G-protein beta WD-40 repeat TOT_040000244 f153869086d4cd57e9bd0892d53d54e4 521 SUPERFAMILY SSF50978 194 497 4.28E-79 T 01-11-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 TOT_040000244 f153869086d4cd57e9bd0892d53d54e4 521 Gene3D G3DSA:2.130.10.10 202 500 3.7E-106 T 01-11-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TOT_040000244 f153869086d4cd57e9bd0892d53d54e4 521 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 308 322 - T 01-11-2018 IPR019775 WD40 repeat, conserved site TOT_040000244 f153869086d4cd57e9bd0892d53d54e4 521 Pfam PF00400 WD domain, G-beta repeat 245 279 2.0E-6 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_040000244 f153869086d4cd57e9bd0892d53d54e4 521 Pfam PF00400 WD domain, G-beta repeat 326 363 4.1E-6 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_040000244 f153869086d4cd57e9bd0892d53d54e4 521 Pfam PF00400 WD domain, G-beta repeat 200 237 1.8E-6 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_040000244 f153869086d4cd57e9bd0892d53d54e4 521 Pfam PF00400 WD domain, G-beta repeat 408 448 5.1E-5 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_040000244 f153869086d4cd57e9bd0892d53d54e4 521 Pfam PF00400 WD domain, G-beta repeat 284 321 1.2E-5 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_040000244 f153869086d4cd57e9bd0892d53d54e4 521 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 350 364 - T 01-11-2018 IPR019775 WD40 repeat, conserved site TOT_040000822 1726d14e93fe13cf894bd0ec9392e65e 123 Gene3D G3DSA:1.10.20.10 1 121 6.8E-54 T 01-11-2018 IPR009072 Histone-fold GO:0046982 TOT_040000822 1726d14e93fe13cf894bd0ec9392e65e 123 PRINTS PR00621 Histone H2B signature 92 105 4.9E-46 T 01-11-2018 IPR000558 Histone H2B GO:0000786|GO:0003677 TOT_040000822 1726d14e93fe13cf894bd0ec9392e65e 123 PRINTS PR00621 Histone H2B signature 34 52 4.9E-46 T 01-11-2018 IPR000558 Histone H2B GO:0000786|GO:0003677 TOT_040000822 1726d14e93fe13cf894bd0ec9392e65e 123 PRINTS PR00621 Histone H2B signature 105 118 4.9E-46 T 01-11-2018 IPR000558 Histone H2B GO:0000786|GO:0003677 TOT_040000822 1726d14e93fe13cf894bd0ec9392e65e 123 PRINTS PR00621 Histone H2B signature 53 73 4.9E-46 T 01-11-2018 IPR000558 Histone H2B GO:0000786|GO:0003677 TOT_040000822 1726d14e93fe13cf894bd0ec9392e65e 123 PRINTS PR00621 Histone H2B signature 75 92 4.9E-46 T 01-11-2018 IPR000558 Histone H2B GO:0000786|GO:0003677 TOT_040000822 1726d14e93fe13cf894bd0ec9392e65e 123 Pfam PF00125 Core histone H2A/H2B/H3/H4 4 97 1.6E-17 T 01-11-2018 IPR007125 Histone H2A/H2B/H3 GO:0000786|GO:0003677 TOT_040000822 1726d14e93fe13cf894bd0ec9392e65e 123 SMART SM00427 24 120 6.2E-66 T 01-11-2018 IPR000558 Histone H2B GO:0000786|GO:0003677 TOT_040000822 1726d14e93fe13cf894bd0ec9392e65e 123 SUPERFAMILY SSF47113 13 121 1.46E-47 T 01-11-2018 IPR009072 Histone-fold GO:0046982 TOT_040000822 1726d14e93fe13cf894bd0ec9392e65e 123 ProSitePatterns PS00357 Histone H2B signature. 89 111 - T 01-11-2018 IPR000558 Histone H2B GO:0000786|GO:0003677 TOT_020000759 20c618a8d757e217288b10b3dd1f868a 414 SUPERFAMILY SSF52402 39 308 2.65E-50 T 01-11-2018 TOT_020000759 20c618a8d757e217288b10b3dd1f868a 414 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 238 338 1.3E-18 T 01-11-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 TOT_020000759 20c618a8d757e217288b10b3dd1f868a 414 Hamap MF_03053 Cytoplasmic tRNA 2-thiolation protein 1 [CTU1]. 2 350 47.847 T 01-11-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 TOT_020000759 20c618a8d757e217288b10b3dd1f868a 414 Pfam PF01171 PP-loop family 52 197 5.9E-16 T 01-11-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 TOT_020000759 20c618a8d757e217288b10b3dd1f868a 414 ProSitePatterns PS01263 Uncharacterized protein family UPF0021 signature. 24 61 - T 01-11-2018 IPR020554 Uncharacterised protein family UPF0021, conserved site TOT_040000291 bd2d159a32a7782168f98e30d7eb913e 748 Gene3D G3DSA:1.25.40.850 492 602 2.8E-75 T 01-11-2018 TOT_040000291 bd2d159a32a7782168f98e30d7eb913e 748 Gene3D G3DSA:3.90.830.10 361 491 2.8E-75 T 01-11-2018 TOT_040000291 bd2d159a32a7782168f98e30d7eb913e 748 Gene3D G3DSA:3.40.50.1910 336 742 2.8E-75 T 01-11-2018 IPR027482 Sec1-like, domain 2 TOT_040000291 bd2d159a32a7782168f98e30d7eb913e 748 Pfam PF00995 Sec1 family 85 747 8.7E-68 T 01-11-2018 IPR001619 Sec1-like protein GO:0006904|GO:0016192 TOT_040000291 bd2d159a32a7782168f98e30d7eb913e 748 SUPERFAMILY SSF56815 80 747 1.7E-70 T 01-11-2018 IPR036045 Sec1-like superfamily GO:0006904|GO:0016192 TOT_030000878 1d5d57f7a85b4ea0139f525f7ac2ff9a 241 Pfam PF04385 Domain of unknown function, DUF529 159 218 9.1E-8 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000551 e52bfee7a52a2f080d5550c7fb8f89fd 293 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 58 225 6.0E-17 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TOT_020000551 e52bfee7a52a2f080d5550c7fb8f89fd 293 SMART SM00175 59 233 3.8E-53 T 01-11-2018 TOT_020000551 e52bfee7a52a2f080d5550c7fb8f89fd 293 PRINTS PR00449 Transforming protein P21 ras signature 152 165 4.0E-24 T 01-11-2018 TOT_020000551 e52bfee7a52a2f080d5550c7fb8f89fd 293 PRINTS PR00449 Transforming protein P21 ras signature 90 112 4.0E-24 T 01-11-2018 TOT_020000551 e52bfee7a52a2f080d5550c7fb8f89fd 293 PRINTS PR00449 Transforming protein P21 ras signature 10 31 4.0E-24 T 01-11-2018 TOT_020000551 e52bfee7a52a2f080d5550c7fb8f89fd 293 PRINTS PR00449 Transforming protein P21 ras signature 208 230 4.0E-24 T 01-11-2018 TOT_020000551 e52bfee7a52a2f080d5550c7fb8f89fd 293 SMART SM00174 59 233 1.8E-6 T 01-11-2018 TOT_020000551 e52bfee7a52a2f080d5550c7fb8f89fd 293 SUPERFAMILY SSF52540 57 239 2.18E-45 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000551 e52bfee7a52a2f080d5550c7fb8f89fd 293 Gene3D G3DSA:3.40.50.300 55 271 3.0E-49 T 01-11-2018 TOT_020000551 e52bfee7a52a2f080d5550c7fb8f89fd 293 SMART SM00176 57 275 0.0052 T 01-11-2018 TOT_020000551 e52bfee7a52a2f080d5550c7fb8f89fd 293 Pfam PF00071 Ras family 58 231 2.6E-42 T 01-11-2018 IPR001806 Small GTPase GO:0003924|GO:0005525 TOT_020000551 e52bfee7a52a2f080d5550c7fb8f89fd 293 SMART SM00173 59 233 4.5E-7 T 01-11-2018 TOT_020000385 7a05f0a3a430deb13ae9da03a0a0b701 1553 Gene3D G3DSA:1.20.1560.10 853 1151 1.6E-10 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000385 7a05f0a3a430deb13ae9da03a0a0b701 1553 SUPERFAMILY SSF90123 845 1162 6.67E-22 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000385 7a05f0a3a430deb13ae9da03a0a0b701 1553 SUPERFAMILY SSF52540 1145 1538 1.4E-28 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000385 7a05f0a3a430deb13ae9da03a0a0b701 1553 Pfam PF00005 ABC transporter 1275 1465 1.8E-17 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000385 7a05f0a3a430deb13ae9da03a0a0b701 1553 ProSitePatterns PS00211 ABC transporters family signature. 655 669 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_020000385 7a05f0a3a430deb13ae9da03a0a0b701 1553 Gene3D G3DSA:3.40.50.300 1240 1544 3.1E-44 T 01-11-2018 TOT_020000385 7a05f0a3a430deb13ae9da03a0a0b701 1553 Gene3D G3DSA:3.40.50.300 513 741 1.5E-36 T 01-11-2018 TOT_020000385 7a05f0a3a430deb13ae9da03a0a0b701 1553 Pfam PF00664 ABC transporter transmembrane region 898 1113 3.1E-10 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TOT_020000385 7a05f0a3a430deb13ae9da03a0a0b701 1553 SMART SM00382 552 752 0.0029 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000385 7a05f0a3a430deb13ae9da03a0a0b701 1553 SMART SM00382 1284 1521 0.43 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000385 7a05f0a3a430deb13ae9da03a0a0b701 1553 Pfam PF00005 ABC transporter 543 670 1.3E-12 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000385 7a05f0a3a430deb13ae9da03a0a0b701 1553 SUPERFAMILY SSF52540 540 728 2.31E-24 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000384 179f27eff24c83051a064b6d24db2653 1535 Gene3D G3DSA:3.40.50.300 1231 1530 2.8E-40 T 01-11-2018 TOT_020000384 179f27eff24c83051a064b6d24db2653 1535 SMART SM00382 552 757 0.23 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000384 179f27eff24c83051a064b6d24db2653 1535 SMART SM00382 1272 1509 0.073 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000384 179f27eff24c83051a064b6d24db2653 1535 Pfam PF00664 ABC transporter transmembrane region 860 1126 7.7E-8 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TOT_020000384 179f27eff24c83051a064b6d24db2653 1535 ProSitePatterns PS00211 ABC transporters family signature. 655 669 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_020000384 179f27eff24c83051a064b6d24db2653 1535 Pfam PF00005 ABC transporter 1263 1453 1.3E-16 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000384 179f27eff24c83051a064b6d24db2653 1535 Pfam PF00005 ABC transporter 543 670 1.2E-12 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000384 179f27eff24c83051a064b6d24db2653 1535 SUPERFAMILY SSF90123 133 477 1.96E-8 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000384 179f27eff24c83051a064b6d24db2653 1535 SUPERFAMILY SSF52540 1225 1523 1.25E-24 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000384 179f27eff24c83051a064b6d24db2653 1535 SUPERFAMILY SSF90123 841 1160 4.45E-21 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000384 179f27eff24c83051a064b6d24db2653 1535 Gene3D G3DSA:3.40.50.300 500 737 9.4E-37 T 01-11-2018 TOT_020000384 179f27eff24c83051a064b6d24db2653 1535 SUPERFAMILY SSF52540 540 731 1.7E-24 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000384 179f27eff24c83051a064b6d24db2653 1535 Gene3D G3DSA:1.20.1560.10 829 1166 1.2E-8 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_040000518 35ce5176efe3418adeeb95f26c709570 127 ProSitePatterns PS00046 Histone H2A signature. 23 29 - T 01-11-2018 IPR032458 Histone H2A conserved site Reactome: R-HSA-3214858 TOT_040000518 35ce5176efe3418adeeb95f26c709570 127 SMART SM00414 4 124 4.3E-75 T 01-11-2018 IPR002119 Histone H2A GO:0000786|GO:0003677|GO:0005634 Reactome: R-HSA-3214858 TOT_040000518 35ce5176efe3418adeeb95f26c709570 127 SUPERFAMILY SSF47113 18 121 1.8E-42 T 01-11-2018 IPR009072 Histone-fold GO:0046982 TOT_040000518 35ce5176efe3418adeeb95f26c709570 127 Pfam PF00125 Core histone H2A/H2B/H3/H4 10 90 1.4E-14 T 01-11-2018 IPR007125 Histone H2A/H2B/H3 GO:0000786|GO:0003677 TOT_040000518 35ce5176efe3418adeeb95f26c709570 127 Pfam PF16211 C-terminus of histone H2A 93 124 4.7E-17 T 01-11-2018 IPR032454 Histone H2A, C-terminal domain Reactome: R-HSA-3214858 TOT_040000518 35ce5176efe3418adeeb95f26c709570 127 PRINTS PR00620 Histone H2A signature 59 72 2.0E-52 T 01-11-2018 IPR002119 Histone H2A GO:0000786|GO:0003677|GO:0005634 Reactome: R-HSA-3214858 TOT_040000518 35ce5176efe3418adeeb95f26c709570 127 PRINTS PR00620 Histone H2A signature 73 87 2.0E-52 T 01-11-2018 IPR002119 Histone H2A GO:0000786|GO:0003677|GO:0005634 Reactome: R-HSA-3214858 TOT_040000518 35ce5176efe3418adeeb95f26c709570 127 PRINTS PR00620 Histone H2A signature 101 119 2.0E-52 T 01-11-2018 IPR002119 Histone H2A GO:0000786|GO:0003677|GO:0005634 Reactome: R-HSA-3214858 TOT_040000518 35ce5176efe3418adeeb95f26c709570 127 PRINTS PR00620 Histone H2A signature 15 37 2.0E-52 T 01-11-2018 IPR002119 Histone H2A GO:0000786|GO:0003677|GO:0005634 Reactome: R-HSA-3214858 TOT_040000518 35ce5176efe3418adeeb95f26c709570 127 PRINTS PR00620 Histone H2A signature 44 59 2.0E-52 T 01-11-2018 IPR002119 Histone H2A GO:0000786|GO:0003677|GO:0005634 Reactome: R-HSA-3214858 TOT_040000518 35ce5176efe3418adeeb95f26c709570 127 Gene3D G3DSA:1.10.20.10 5 127 1.6E-60 T 01-11-2018 IPR009072 Histone-fold GO:0046982 TOT_040000720 09066561304161c9197b1e43a50f7726 179 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 68 82 2.6E-12 T 01-11-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TOT_040000720 09066561304161c9197b1e43a50f7726 179 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 113 127 2.6E-12 T 01-11-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TOT_040000720 09066561304161c9197b1e43a50f7726 179 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 87 100 2.6E-12 T 01-11-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TOT_040000720 09066561304161c9197b1e43a50f7726 179 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 103 113 2.6E-12 T 01-11-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TOT_040000720 09066561304161c9197b1e43a50f7726 179 Gene3D G3DSA:3.30.1330.30 15 159 4.1E-28 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like TOT_040000720 09066561304161c9197b1e43a50f7726 179 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 66 140 1.2E-16 T 01-11-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 TOT_040000720 09066561304161c9197b1e43a50f7726 179 SUPERFAMILY SSF55315 64 149 4.71E-23 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like TOT_030000012 45023df2e6e74a036cc369e2feb4cc21 1761 Pfam PF04385 Domain of unknown function, DUF529 1416 1448 3.1E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_030000012 45023df2e6e74a036cc369e2feb4cc21 1761 Pfam PF04385 Domain of unknown function, DUF529 551 600 6.5E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_030000012 45023df2e6e74a036cc369e2feb4cc21 1761 Pfam PF04385 Domain of unknown function, DUF529 900 965 2.1E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000275 e13ec48cf543087743badc0b769d4fe6 132 SUPERFAMILY SSF47473 6 128 2.29E-10 T 01-11-2018 IPR011992 EF-hand domain pair TOT_010000275 e13ec48cf543087743badc0b769d4fe6 132 Gene3D G3DSA:1.10.238.10 2 132 3.4E-8 T 01-11-2018 TOT_020000951 e40ec93e16868352adfc84d52a1ab65f 619 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 575 609 4.5E-8 T 01-11-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOT_020000951 e40ec93e16868352adfc84d52a1ab65f 619 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 72 104 3.1E-6 T 01-11-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOT_020000951 e40ec93e16868352adfc84d52a1ab65f 619 Gene3D G3DSA:1.10.490.170 6 173 1.1E-34 T 01-11-2018 TOT_020000951 e40ec93e16868352adfc84d52a1ab65f 619 SUPERFAMILY SSF53738 231 322 1.18E-7 T 01-11-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOT_020000951 e40ec93e16868352adfc84d52a1ab65f 619 Gene3D G3DSA:3.30.310.50 532 618 2.7E-18 T 01-11-2018 TOT_020000951 e40ec93e16868352adfc84d52a1ab65f 619 SUPERFAMILY SSF55957 523 615 2.88E-16 T 01-11-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOT_020000951 e40ec93e16868352adfc84d52a1ab65f 619 Gene3D G3DSA:3.40.120.10 227 347 4.1E-5 T 01-11-2018 TOT_020000951 e40ec93e16868352adfc84d52a1ab65f 619 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 76 85 - T 01-11-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOT_020000951 e40ec93e16868352adfc84d52a1ab65f 619 SUPERFAMILY SSF53738 17 117 1.41E-13 T 01-11-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOT_020000839 26ca334b45bcaf875d723b8b57284f72 928 Gene3D G3DSA:3.30.450.40 251 389 1.7E-11 T 01-11-2018 IPR029016 GAF-like domain superfamily TOT_020000839 26ca334b45bcaf875d723b8b57284f72 928 SUPERFAMILY SSF55781 257 385 6.13E-11 T 01-11-2018 TOT_020000839 26ca334b45bcaf875d723b8b57284f72 928 SUPERFAMILY SSF55781 661 880 5.61E-15 T 01-11-2018 TOT_020000839 26ca334b45bcaf875d723b8b57284f72 928 SMART SM00065 675 889 0.0027 T 01-11-2018 IPR003018 GAF domain GO:0005515 TOT_030000565 e2989d642bad75ea7a14c22da1f352ad 476 SUPERFAMILY SSF54001 121 438 2.47E-66 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily TOT_030000565 e2989d642bad75ea7a14c22da1f352ad 476 SMART SM00848 128 183 2.9E-6 T 01-11-2018 IPR013201 Cathepsin propeptide inhibitor domain (I29) Reactome: R-HSA-2132295 TOT_030000565 e2989d642bad75ea7a14c22da1f352ad 476 SMART SM00645 234 445 4.3E-55 T 01-11-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 TOT_030000565 e2989d642bad75ea7a14c22da1f352ad 476 Gene3D G3DSA:3.90.70.10 105 445 1.5E-69 T 01-11-2018 TOT_030000565 e2989d642bad75ea7a14c22da1f352ad 476 Pfam PF00112 Papain family cysteine protease 236 439 1.0E-48 T 01-11-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 TOT_030000565 e2989d642bad75ea7a14c22da1f352ad 476 Pfam PF08246 Cathepsin propeptide inhibitor domain (I29) 128 182 5.6E-6 T 01-11-2018 IPR013201 Cathepsin propeptide inhibitor domain (I29) Reactome: R-HSA-2132295 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 ProSitePatterns PS00115 Eukaryotic RNA polymerase II heptapeptide repeat. 1621 1627 - T 01-11-2018 IPR000684 RNA polymerase II, heptapeptide repeat, eukaryotic GO:0003677|GO:0005665|GO:0006366 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Pfam PF04992 RNA polymerase Rpb1, domain 6 886 1074 1.9E-49 T 01-11-2018 IPR007075 RNA polymerase Rpb1, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-203927|Reactome: R-HSA-452723|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 ProSitePatterns PS00115 Eukaryotic RNA polymerase II heptapeptide repeat. 1672 1678 - T 01-11-2018 IPR000684 RNA polymerase II, heptapeptide repeat, eukaryotic GO:0003677|GO:0005665|GO:0006366 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 ProSitePatterns PS00115 Eukaryotic RNA polymerase II heptapeptide repeat. 1614 1620 - T 01-11-2018 IPR000684 RNA polymerase II, heptapeptide repeat, eukaryotic GO:0003677|GO:0005665|GO:0006366 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Pfam PF04998 RNA polymerase Rpb1, domain 5 820 1416 1.9E-99 T 01-11-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 ProSitePatterns PS00115 Eukaryotic RNA polymerase II heptapeptide repeat. 1665 1671 - T 01-11-2018 IPR000684 RNA polymerase II, heptapeptide repeat, eukaryotic GO:0003677|GO:0005665|GO:0006366 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Pfam PF05001 RNA polymerase Rpb1 C-terminal repeat 1680 1691 0.054 T 01-11-2018 IPR000684 RNA polymerase II, heptapeptide repeat, eukaryotic GO:0003677|GO:0005665|GO:0006366 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Pfam PF05001 RNA polymerase Rpb1 C-terminal repeat 1650 1665 0.017 T 01-11-2018 IPR000684 RNA polymerase II, heptapeptide repeat, eukaryotic GO:0003677|GO:0005665|GO:0006366 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Pfam PF05001 RNA polymerase Rpb1 C-terminal repeat 1594 1607 0.0056 T 01-11-2018 IPR000684 RNA polymerase II, heptapeptide repeat, eukaryotic GO:0003677|GO:0005665|GO:0006366 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Pfam PF05001 RNA polymerase Rpb1 C-terminal repeat 1608 1621 0.033 T 01-11-2018 IPR000684 RNA polymerase II, heptapeptide repeat, eukaryotic GO:0003677|GO:0005665|GO:0006366 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Pfam PF05001 RNA polymerase Rpb1 C-terminal repeat 1622 1635 0.0052 T 01-11-2018 IPR000684 RNA polymerase II, heptapeptide repeat, eukaryotic GO:0003677|GO:0005665|GO:0006366 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Pfam PF05001 RNA polymerase Rpb1 C-terminal repeat 1565 1578 0.026 T 01-11-2018 IPR000684 RNA polymerase II, heptapeptide repeat, eukaryotic GO:0003677|GO:0005665|GO:0006366 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Pfam PF05001 RNA polymerase Rpb1 C-terminal repeat 1636 1649 0.0053 T 01-11-2018 IPR000684 RNA polymerase II, heptapeptide repeat, eukaryotic GO:0003677|GO:0005665|GO:0006366 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Pfam PF05001 RNA polymerase Rpb1 C-terminal repeat 1666 1679 0.0043 T 01-11-2018 IPR000684 RNA polymerase II, heptapeptide repeat, eukaryotic GO:0003677|GO:0005665|GO:0006366 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Pfam PF05001 RNA polymerase Rpb1 C-terminal repeat 1601 1614 0.0056 T 01-11-2018 IPR000684 RNA polymerase II, heptapeptide repeat, eukaryotic GO:0003677|GO:0005665|GO:0006366 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 ProSitePatterns PS00115 Eukaryotic RNA polymerase II heptapeptide repeat. 1679 1685 - T 01-11-2018 IPR000684 RNA polymerase II, heptapeptide repeat, eukaryotic GO:0003677|GO:0005665|GO:0006366 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Gene3D G3DSA:3.30.1360.140 1159 1296 5.5E-33 T 01-11-2018 IPR038593 RNA polymerase Rpb1, domain 7 superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-203927|Reactome: R-HSA-452723|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Gene3D G3DSA:2.40.40.20 333 503 2.3E-72 T 01-11-2018 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Gene3D G3DSA:1.10.132.30 678 822 2.0E-50 T 01-11-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 ProSitePatterns PS00115 Eukaryotic RNA polymerase II heptapeptide repeat. 1607 1613 - T 01-11-2018 IPR000684 RNA polymerase II, heptapeptide repeat, eukaryotic GO:0003677|GO:0005665|GO:0006366 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 ProSitePatterns PS00115 Eukaryotic RNA polymerase II heptapeptide repeat. 1686 1692 - T 01-11-2018 IPR000684 RNA polymerase II, heptapeptide repeat, eukaryotic GO:0003677|GO:0005665|GO:0006366 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Gene3D G3DSA:1.10.274.100 512 676 9.7E-50 T 01-11-2018 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Pfam PF04983 RNA polymerase Rpb1, domain 3 511 682 2.2E-45 T 01-11-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Gene3D G3DSA:1.20.120.1280 7 122 1.5E-29 T 01-11-2018 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Gene3D G3DSA:1.20.120.1280 256 306 8.2E-8 T 01-11-2018 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Gene3D G3DSA:3.30.1490.180 376 439 2.3E-72 T 01-11-2018 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Pfam PF04990 RNA polymerase Rpb1, domain 7 1159 1295 2.6E-37 T 01-11-2018 IPR007073 RNA polymerase Rpb1, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-203927|Reactome: R-HSA-452723|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Gene3D G3DSA:1.10.150.390 1419 1463 4.6E-15 T 01-11-2018 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 SUPERFAMILY SSF64484 10 1468 0.0 T 01-11-2018 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Pfam PF00623 RNA polymerase Rpb1, domain 2 343 508 7.1E-73 T 01-11-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Gene3D G3DSA:2.20.25.410 859 901 2.9E-8 T 01-11-2018 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 SMART SM00663 234 536 9.4E-184 T 01-11-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Pfam PF05000 RNA polymerase Rpb1, domain 4 711 813 1.6E-36 T 01-11-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 Pfam PF04997 RNA polymerase Rpb1, domain 1 17 341 2.5E-98 T 01-11-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_030000665 6b83e554f494e9007461b1b804d51151 1712 ProSitePatterns PS00115 Eukaryotic RNA polymerase II heptapeptide repeat. 1628 1634 - T 01-11-2018 IPR000684 RNA polymerase II, heptapeptide repeat, eukaryotic GO:0003677|GO:0005665|GO:0006366 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_010000404 82a15e1f19e1426848a9b083dffae5a0 728 SUPERFAMILY SSF55681 104 616 1.23E-110 T 01-11-2018 TOT_010000404 82a15e1f19e1426848a9b083dffae5a0 728 SUPERFAMILY SSF52954 600 721 2.87E-32 T 01-11-2018 TOT_010000404 82a15e1f19e1426848a9b083dffae5a0 728 Pfam PF03129 Anticodon binding domain 613 704 1.7E-21 T 01-11-2018 IPR004154 Anticodon-binding TOT_010000404 82a15e1f19e1426848a9b083dffae5a0 728 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 285 360 5.0E-8 T 01-11-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TOT_010000404 82a15e1f19e1426848a9b083dffae5a0 728 Gene3D G3DSA:1.10.30.30 479 558 3.1E-195 T 01-11-2018 TOT_010000404 82a15e1f19e1426848a9b083dffae5a0 728 Gene3D G3DSA:3.30.930.10 106 594 3.1E-195 T 01-11-2018 TOT_010000404 82a15e1f19e1426848a9b083dffae5a0 728 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 102 704 1.8E-201 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TOT_010000404 82a15e1f19e1426848a9b083dffae5a0 728 PRINTS PR01043 Glycyl-tRNA synthetase signature 287 304 1.4E-49 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TOT_010000404 82a15e1f19e1426848a9b083dffae5a0 728 PRINTS PR01043 Glycyl-tRNA synthetase signature 319 336 1.4E-49 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TOT_010000404 82a15e1f19e1426848a9b083dffae5a0 728 PRINTS PR01043 Glycyl-tRNA synthetase signature 336 346 1.4E-49 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TOT_010000404 82a15e1f19e1426848a9b083dffae5a0 728 PRINTS PR01043 Glycyl-tRNA synthetase signature 652 671 1.4E-49 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TOT_010000404 82a15e1f19e1426848a9b083dffae5a0 728 PRINTS PR01043 Glycyl-tRNA synthetase signature 119 133 1.4E-49 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TOT_010000404 82a15e1f19e1426848a9b083dffae5a0 728 PRINTS PR01043 Glycyl-tRNA synthetase signature 566 578 1.4E-49 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TOT_010000404 82a15e1f19e1426848a9b083dffae5a0 728 Gene3D G3DSA:1.20.1430.20 177 269 3.1E-195 T 01-11-2018 TOT_010000404 82a15e1f19e1426848a9b083dffae5a0 728 Gene3D G3DSA:3.40.50.800 611 726 2.5E-40 T 01-11-2018 IPR036621 Anticodon-binding domain superfamily TOT_020000496 19bc8c1f2fb9de1166b6807781a63881 887 Pfam PF00270 DEAD/DEAH box helicase 189 373 8.1E-20 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TOT_020000496 19bc8c1f2fb9de1166b6807781a63881 887 Pfam PF00271 Helicase conserved C-terminal domain 412 515 6.6E-14 T 01-11-2018 IPR001650 Helicase, C-terminal TOT_020000496 19bc8c1f2fb9de1166b6807781a63881 887 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 324 333 - T 01-11-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site TOT_020000496 19bc8c1f2fb9de1166b6807781a63881 887 SUPERFAMILY SSF52540 229 536 5.4E-52 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000496 19bc8c1f2fb9de1166b6807781a63881 887 SMART SM00490 437 517 1.4E-20 T 01-11-2018 IPR001650 Helicase, C-terminal TOT_020000496 19bc8c1f2fb9de1166b6807781a63881 887 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 176 622 1.6E-128 T 01-11-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 TOT_020000496 19bc8c1f2fb9de1166b6807781a63881 887 Gene3D G3DSA:3.40.50.300 393 526 2.6E-35 T 01-11-2018 TOT_020000496 19bc8c1f2fb9de1166b6807781a63881 887 Pfam PF16124 RecQ zinc-binding 530 601 5.9E-11 T 01-11-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain TOT_020000496 19bc8c1f2fb9de1166b6807781a63881 887 SMART SM00487 181 402 5.3E-27 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOT_020000496 19bc8c1f2fb9de1166b6807781a63881 887 Gene3D G3DSA:3.40.50.300 148 392 3.7E-76 T 01-11-2018 TOT_010000195 d31c798cdc59319dfea49c326e596ba3 706 Pfam PF00439 Bromodomain 184 267 6.0E-16 T 01-11-2018 IPR001487 Bromodomain GO:0005515 TOT_010000195 d31c798cdc59319dfea49c326e596ba3 706 Gene3D G3DSA:1.20.920.10 124 287 1.8E-28 T 01-11-2018 IPR036427 Bromodomain-like superfamily GO:0005515 TOT_010000195 d31c798cdc59319dfea49c326e596ba3 706 SMART SM00297 176 282 2.2E-12 T 01-11-2018 IPR001487 Bromodomain GO:0005515 TOT_010000195 d31c798cdc59319dfea49c326e596ba3 706 PRINTS PR00503 Bromodomain signature 210 226 2.2E-7 T 01-11-2018 IPR001487 Bromodomain GO:0005515 TOT_010000195 d31c798cdc59319dfea49c326e596ba3 706 PRINTS PR00503 Bromodomain signature 244 263 2.2E-7 T 01-11-2018 IPR001487 Bromodomain GO:0005515 TOT_010000195 d31c798cdc59319dfea49c326e596ba3 706 PRINTS PR00503 Bromodomain signature 226 244 2.2E-7 T 01-11-2018 IPR001487 Bromodomain GO:0005515 TOT_010000195 d31c798cdc59319dfea49c326e596ba3 706 SUPERFAMILY SSF47370 169 278 2.49E-28 T 01-11-2018 IPR036427 Bromodomain-like superfamily GO:0005515 TOT_030000803 03fd9e1c1e0d63d966cf556dc8049972 469 SUPERFAMILY SSF103473 17 464 3.66E-42 T 01-11-2018 IPR036259 MFS transporter superfamily TOT_030000803 03fd9e1c1e0d63d966cf556dc8049972 469 PRINTS PR00171 Sugar transporter signature 373 394 7.5E-11 T 01-11-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TOT_030000803 03fd9e1c1e0d63d966cf556dc8049972 469 PRINTS PR00171 Sugar transporter signature 284 294 7.5E-11 T 01-11-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TOT_030000803 03fd9e1c1e0d63d966cf556dc8049972 469 PRINTS PR00171 Sugar transporter signature 114 133 7.5E-11 T 01-11-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TOT_030000803 03fd9e1c1e0d63d966cf556dc8049972 469 PRINTS PR00171 Sugar transporter signature 396 408 7.5E-11 T 01-11-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TOT_030000803 03fd9e1c1e0d63d966cf556dc8049972 469 Gene3D G3DSA:1.20.1250.20 2 467 1.2E-87 T 01-11-2018 TOT_030000803 03fd9e1c1e0d63d966cf556dc8049972 469 Pfam PF00083 Sugar (and other) transporter 51 464 2.5E-70 T 01-11-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 TOT_010000506 6250ec2e186a5c4f5d9ec8a152268b21 375 Pfam PF01633 Choline/ethanolamine kinase 83 315 2.5E-36 T 01-11-2018 TOT_010000506 6250ec2e186a5c4f5d9ec8a152268b21 375 SUPERFAMILY SSF56112 33 375 1.9E-53 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily TOT_030000818 92a3c8efc65ce20ca25a55f892cc17ff 363 SUPERFAMILY SSF140586 9 97 8.11E-26 T 01-11-2018 IPR036189 mRNA decapping protein 2, Box A domain superfamily GO:0003723|GO:0016787|GO:0030145 Reactome: R-HSA-380994|Reactome: R-HSA-430039|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604 TOT_030000818 92a3c8efc65ce20ca25a55f892cc17ff 363 SUPERFAMILY SSF55811 71 210 2.3E-21 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TOT_030000818 92a3c8efc65ce20ca25a55f892cc17ff 363 SMART SM01125 12 98 8.4E-19 T 01-11-2018 IPR007722 mRNA decapping protein 2, Box A domain GO:0003723|GO:0016787|GO:0030145 Reactome: R-HSA-380994|Reactome: R-HSA-430039|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604 TOT_030000818 92a3c8efc65ce20ca25a55f892cc17ff 363 ProSitePatterns PS00893 Nudix box signature. 132 153 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TOT_030000818 92a3c8efc65ce20ca25a55f892cc17ff 363 Pfam PF05026 Dcp2, box A domain 14 97 3.3E-21 T 01-11-2018 IPR007722 mRNA decapping protein 2, Box A domain GO:0003723|GO:0016787|GO:0030145 Reactome: R-HSA-380994|Reactome: R-HSA-430039|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604 TOT_030000818 92a3c8efc65ce20ca25a55f892cc17ff 363 Pfam PF00293 NUDIX domain 104 210 1.5E-12 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TOT_030000818 92a3c8efc65ce20ca25a55f892cc17ff 363 Gene3D G3DSA:3.90.79.10 100 231 1.8E-57 T 01-11-2018 TOT_030000818 92a3c8efc65ce20ca25a55f892cc17ff 363 Gene3D G3DSA:1.10.10.1050 15 99 1.8E-57 T 01-11-2018 IPR036189 mRNA decapping protein 2, Box A domain superfamily GO:0003723|GO:0016787|GO:0030145 Reactome: R-HSA-380994|Reactome: R-HSA-430039|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604 TOT_020000949 7e472e44573dfa1dcd094a840c5f88a2 201 Pfam PF00957 Synaptobrevin 140 199 5.4E-8 T 01-11-2018 IPR001388 Synaptobrevin GO:0016021|GO:0016192 TOT_020000949 7e472e44573dfa1dcd094a840c5f88a2 201 Gene3D G3DSA:1.20.5.110 143 201 3.5E-12 T 01-11-2018 TOT_020000949 7e472e44573dfa1dcd094a840c5f88a2 201 SUPERFAMILY SSF64356 5 138 5.04E-27 T 01-11-2018 IPR011012 Longin-like domain superfamily TOT_020000949 7e472e44573dfa1dcd094a840c5f88a2 201 Gene3D G3DSA:3.30.450.50 2 138 6.7E-27 T 01-11-2018 TOT_020000949 7e472e44573dfa1dcd094a840c5f88a2 201 SMART SM01270 45 127 4.3E-7 T 01-11-2018 IPR010908 Longin domain Reactome: R-HSA-204005 TOT_020000949 7e472e44573dfa1dcd094a840c5f88a2 201 SUPERFAMILY SSF58038 134 197 1.47E-9 T 01-11-2018 TOT_020000499 15b29a0349d1c590dd23b72149c53fdc 1338 Pfam PF02263 Guanylate-binding protein, N-terminal domain 138 231 1.3E-9 T 01-11-2018 IPR015894 Guanylate-binding protein, N-terminal GO:0003924|GO:0005525 TOT_020000499 15b29a0349d1c590dd23b72149c53fdc 1338 SUPERFAMILY SSF52540 124 400 4.83E-19 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010001314 570c709210248b4d49ee46589c64f2ca 210 Gene3D G3DSA:1.10.520.20 29 127 2.2E-11 T 01-11-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TOT_010001314 570c709210248b4d49ee46589c64f2ca 210 PRINTS PR00125 ATP synthase delta subunit signature 30 49 1.7E-16 T 01-11-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TOT_010001314 570c709210248b4d49ee46589c64f2ca 210 PRINTS PR00125 ATP synthase delta subunit signature 103 114 1.7E-16 T 01-11-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TOT_010001314 570c709210248b4d49ee46589c64f2ca 210 PRINTS PR00125 ATP synthase delta subunit signature 181 199 1.7E-16 T 01-11-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TOT_010001314 570c709210248b4d49ee46589c64f2ca 210 PRINTS PR00125 ATP synthase delta subunit signature 166 181 1.7E-16 T 01-11-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TOT_010001314 570c709210248b4d49ee46589c64f2ca 210 PRINTS PR00125 ATP synthase delta subunit signature 114 128 1.7E-16 T 01-11-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TOT_010001314 570c709210248b4d49ee46589c64f2ca 210 SUPERFAMILY SSF47928 28 134 1.23E-12 T 01-11-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TOT_010001314 570c709210248b4d49ee46589c64f2ca 210 Hamap MF_01416 ATP synthase subunit delta [atpD]. 26 208 15.81 T 01-11-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TOT_010001314 570c709210248b4d49ee46589c64f2ca 210 Pfam PF00213 ATP synthase delta (OSCP) subunit 30 206 3.1E-41 T 01-11-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TOT_010001314 570c709210248b4d49ee46589c64f2ca 210 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 33 206 2.1E-27 T 01-11-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TOT_030000321 256bacbb6a1f473613472bdd78fe21c0 612 Pfam PF00847 AP2 domain 266 314 4.1E-14 T 01-11-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 TOT_030000321 256bacbb6a1f473613472bdd78fe21c0 612 Pfam PF00847 AP2 domain 337 385 4.2E-13 T 01-11-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 TOT_020000487 125775175a9c7e7e42bddf816e657ac7 751 Pfam PF01384 Phosphate transporter family 26 732 3.6E-92 T 01-11-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 TOT_030000203 17b5e63afdd99395e6622b402d929461 2274 SMART SM00490 1678 1760 1.2E-4 T 01-11-2018 IPR001650 Helicase, C-terminal TOT_030000203 17b5e63afdd99395e6622b402d929461 2274 Gene3D G3DSA:3.40.50.300 1028 1228 3.6E-42 T 01-11-2018 TOT_030000203 17b5e63afdd99395e6622b402d929461 2274 Pfam PF00270 DEAD/DEAH box helicase 1049 1210 3.5E-17 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TOT_030000203 17b5e63afdd99395e6622b402d929461 2274 SMART SM00487 1041 1243 3.7E-20 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOT_030000203 17b5e63afdd99395e6622b402d929461 2274 SUPERFAMILY SSF52540 1059 1770 7.65E-30 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010000218 b4898a0722d049a632161dafc6a78ce6 1101 Gene3D G3DSA:1.25.40.860 283 376 4.5E-10 T 01-11-2018 TOT_010000218 b4898a0722d049a632161dafc6a78ce6 1101 Pfam PF01399 PCI domain 459 538 2.1E-6 T 01-11-2018 IPR000717 Proteasome component (PCI) domain TOT_010000218 b4898a0722d049a632161dafc6a78ce6 1101 Hamap MF_03000 Eukaryotic translation initiation factor 3 subunit A [EIF3A]. 1 1016 25.953 T 01-11-2018 IPR027512 Eukaryotic translation initiation factor 3 subunit A GO:0005852 Reactome: R-HSA-156827|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706 TOT_010000218 b4898a0722d049a632161dafc6a78ce6 1101 Gene3D G3DSA:4.10.860.10 224 263 1.0E-8 T 01-11-2018 TOT_030000610 188e48fb4c58631b6468e1ea447ca1d5 1265 Pfam PF04385 Domain of unknown function, DUF529 1049 1113 2.9E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000832 d340e44786428758b0f29a41fedc71e6 159 Pfam PF01287 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 82 156 8.1E-26 T 01-11-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 TOT_010000832 d340e44786428758b0f29a41fedc71e6 159 PIRSF PIRSF003025 1 159 7.8E-65 T 01-11-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 TOT_010000832 d340e44786428758b0f29a41fedc71e6 159 SUPERFAMILY SSF50249 83 158 3.31E-20 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold TOT_010000832 d340e44786428758b0f29a41fedc71e6 159 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 21 69 2.4E-5 T 01-11-2018 IPR013185 Translation elongation factor, KOW-like TOT_010000832 d340e44786428758b0f29a41fedc71e6 159 ProSitePatterns PS00302 Eukaryotic initiation factor 5A hypusine signature. 47 54 - T 01-11-2018 IPR019769 Translation elongation factor, IF5A, hypusine site GO:0003723|GO:0003746|GO:0043022|GO:0045901|GO:0045905 TOT_010000832 d340e44786428758b0f29a41fedc71e6 159 SMART SM01376 82 156 6.9E-28 T 01-11-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 TOT_010000832 d340e44786428758b0f29a41fedc71e6 159 SUPERFAMILY SSF50104 12 90 1.96E-28 T 01-11-2018 IPR008991 Translation protein SH3-like domain superfamily TOT_010000832 d340e44786428758b0f29a41fedc71e6 159 TIGRFAM TIGR00037 eIF_5A: translation elongation factor IF5A 14 155 2.1E-37 T 01-11-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 TOT_010000832 d340e44786428758b0f29a41fedc71e6 159 Gene3D G3DSA:2.40.50.140 83 159 1.1E-25 T 01-11-2018 TOT_010000832 d340e44786428758b0f29a41fedc71e6 159 Gene3D G3DSA:2.30.30.30 1 82 8.0E-42 T 01-11-2018 IPR014722 Ribosomal protein L2, domain 2 TOT_010000589 547ef0da0ee214c687c28ad3a8d082b1 255 Pfam PF16046 FAM76 protein 44 188 1.5E-21 T 01-11-2018 IPR032017 FAM76 protein TOT_030000601 b8c563e9a6f49a5810b815ba22e07549 1627 SUPERFAMILY SSF55073 115 367 4.55E-18 T 01-11-2018 IPR029787 Nucleotide cyclase TOT_030000601 b8c563e9a6f49a5810b815ba22e07549 1627 SUPERFAMILY SSF55073 667 783 2.2E-17 T 01-11-2018 IPR029787 Nucleotide cyclase TOT_030000601 b8c563e9a6f49a5810b815ba22e07549 1627 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 734 784 6.2E-7 T 01-11-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 TOT_030000601 b8c563e9a6f49a5810b815ba22e07549 1627 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 115 364 1.0E-6 T 01-11-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 TOT_030000601 b8c563e9a6f49a5810b815ba22e07549 1627 Gene3D G3DSA:3.30.70.1230 657 815 1.0E-22 T 01-11-2018 IPR029787 Nucleotide cyclase TOT_020000562 ca2a7c6f15a84edea6ce6f8c4d54aeb9 1092 Pfam PF08389 Exportin 1-like protein 1 120 1.0E-5 T 01-11-2018 IPR013598 Exportin-1/Importin-beta-like TOT_020000562 ca2a7c6f15a84edea6ce6f8c4d54aeb9 1092 SUPERFAMILY SSF48371 540 984 1.68E-11 T 01-11-2018 IPR016024 Armadillo-type fold TOT_020000562 ca2a7c6f15a84edea6ce6f8c4d54aeb9 1092 Gene3D G3DSA:1.25.10.10 1 285 4.3E-16 T 01-11-2018 IPR011989 Armadillo-like helical TOT_020000562 ca2a7c6f15a84edea6ce6f8c4d54aeb9 1092 Gene3D G3DSA:1.25.10.10 541 853 1.3E-16 T 01-11-2018 IPR011989 Armadillo-like helical TOT_020000004 ba7b9f6562b4e367cfbbc16a49f87418 2396 Pfam PF04385 Domain of unknown function, DUF529 258 326 6.7E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000004 ba7b9f6562b4e367cfbbc16a49f87418 2396 Pfam PF04385 Domain of unknown function, DUF529 52 114 1.1E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000004 ba7b9f6562b4e367cfbbc16a49f87418 2396 Pfam PF04385 Domain of unknown function, DUF529 879 938 1.7E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 Pfam PF00012 Hsp70 protein 5 613 2.7E-255 T 01-11-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 335 349 - T 01-11-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 Gene3D G3DSA:1.20.1270.10 511 614 5.4E-33 T 01-11-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 Gene3D G3DSA:2.60.34.10 382 510 1.0E-61 T 01-11-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 Gene3D G3DSA:3.30.420.40 188 361 3.9E-176 T 01-11-2018 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 SUPERFAMILY SSF53067 191 383 3.83E-64 T 01-11-2018 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 SUPERFAMILY SSF53067 4 187 1.61E-72 T 01-11-2018 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 SUPERFAMILY SSF100934 538 619 1.02E-24 T 01-11-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 Gene3D G3DSA:3.30.30.30 67 122 3.9E-176 T 01-11-2018 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 8 15 - T 01-11-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 197 210 - T 01-11-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 PRINTS PR00301 70kDa heat shock protein signature 32 44 1.7E-86 T 01-11-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 PRINTS PR00301 70kDa heat shock protein signature 332 348 1.7E-86 T 01-11-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 PRINTS PR00301 70kDa heat shock protein signature 142 162 1.7E-86 T 01-11-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 PRINTS PR00301 70kDa heat shock protein signature 203 213 1.7E-86 T 01-11-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 PRINTS PR00301 70kDa heat shock protein signature 364 384 1.7E-86 T 01-11-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 PRINTS PR00301 70kDa heat shock protein signature 472 488 1.7E-86 T 01-11-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 PRINTS PR00301 70kDa heat shock protein signature 54 62 1.7E-86 T 01-11-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 PRINTS PR00301 70kDa heat shock protein signature 4 17 1.7E-86 T 01-11-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 PRINTS PR00301 70kDa heat shock protein signature 391 410 1.7E-86 T 01-11-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 Gene3D G3DSA:3.30.420.40 6 378 3.9E-176 T 01-11-2018 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 Gene3D G3DSA:3.90.640.10 229 313 3.9E-176 T 01-11-2018 TOT_020000137 c8b84cf4389fddbb7a104c28179a716f 648 SUPERFAMILY SSF100920 387 544 1.31E-61 T 01-11-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 TOT_030000479 0a2fe7b9f8b1fcaa74344db37b833909 232 Pfam PF06201 PITH domain 155 226 2.4E-8 T 01-11-2018 IPR010400 PITH domain TOT_030000479 0a2fe7b9f8b1fcaa74344db37b833909 232 Pfam PF06201 PITH domain 39 115 7.8E-10 T 01-11-2018 IPR010400 PITH domain TOT_030000479 0a2fe7b9f8b1fcaa74344db37b833909 232 Gene3D G3DSA:2.60.120.470 27 117 1.3E-7 T 01-11-2018 IPR037047 PITH domain superfamily TOT_030000479 0a2fe7b9f8b1fcaa74344db37b833909 232 Gene3D G3DSA:2.60.120.470 138 232 7.2E-13 T 01-11-2018 IPR037047 PITH domain superfamily TOT_030000479 0a2fe7b9f8b1fcaa74344db37b833909 232 SUPERFAMILY SSF49785 156 226 8.5E-10 T 01-11-2018 IPR008979 Galactose-binding-like domain superfamily TOT_030000479 0a2fe7b9f8b1fcaa74344db37b833909 232 SUPERFAMILY SSF49785 38 114 5.7E-7 T 01-11-2018 IPR008979 Galactose-binding-like domain superfamily TOT_020000025 36c25946ceab5543b1377181e38e97a2 445 PIRSF PIRSF037913 1 440 7.6E-204 T 01-11-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 TOT_020000025 36c25946ceab5543b1377181e38e97a2 445 SUPERFAMILY SSF52768 3 371 1.34E-116 T 01-11-2018 IPR023696 Ureohydrolase domain superfamily TOT_020000025 36c25946ceab5543b1377181e38e97a2 445 Pfam PF00850 Histone deacetylase domain 22 313 2.5E-79 T 01-11-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TOT_020000025 36c25946ceab5543b1377181e38e97a2 445 PRINTS PR01270 Histone deacetylase superfamily signature 133 156 2.7E-23 T 01-11-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TOT_020000025 36c25946ceab5543b1377181e38e97a2 445 PRINTS PR01270 Histone deacetylase superfamily signature 165 180 2.7E-23 T 01-11-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TOT_020000025 36c25946ceab5543b1377181e38e97a2 445 PRINTS PR01270 Histone deacetylase superfamily signature 250 260 2.7E-23 T 01-11-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TOT_020000025 36c25946ceab5543b1377181e38e97a2 445 Gene3D G3DSA:3.40.800.20 1 378 1.6E-152 T 01-11-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TOT_020000025 36c25946ceab5543b1377181e38e97a2 445 PRINTS PR01271 Histone deacetylase signature 152 168 4.1E-48 T 01-11-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 TOT_020000025 36c25946ceab5543b1377181e38e97a2 445 PRINTS PR01271 Histone deacetylase signature 90 107 4.1E-48 T 01-11-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 TOT_020000025 36c25946ceab5543b1377181e38e97a2 445 PRINTS PR01271 Histone deacetylase signature 24 41 4.1E-48 T 01-11-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 TOT_020000025 36c25946ceab5543b1377181e38e97a2 445 PRINTS PR01271 Histone deacetylase signature 57 75 4.1E-48 T 01-11-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 TOT_020000025 36c25946ceab5543b1377181e38e97a2 445 PRINTS PR01271 Histone deacetylase signature 111 131 4.1E-48 T 01-11-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 TOT_020000025 36c25946ceab5543b1377181e38e97a2 445 PRINTS PR01271 Histone deacetylase signature 228 246 4.1E-48 T 01-11-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 TOT_020000025 36c25946ceab5543b1377181e38e97a2 445 PRINTS PR01271 Histone deacetylase signature 211 224 4.1E-48 T 01-11-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 TOT_030000492 eb83e715b65c3b3893108538611ff378 207 Gene3D G3DSA:1.50.40.10 11 190 3.3E-36 T 01-11-2018 IPR023395 Mitochondrial carrier domain superfamily TOT_030000492 eb83e715b65c3b3893108538611ff378 207 Pfam PF00153 Mitochondrial carrier protein 17 112 2.7E-18 T 01-11-2018 IPR018108 Mitochondrial substrate/solute carrier TOT_030000492 eb83e715b65c3b3893108538611ff378 207 Pfam PF00153 Mitochondrial carrier protein 136 179 5.5E-6 T 01-11-2018 IPR018108 Mitochondrial substrate/solute carrier TOT_030000492 eb83e715b65c3b3893108538611ff378 207 SUPERFAMILY SSF103506 10 173 3.4E-29 T 01-11-2018 IPR023395 Mitochondrial carrier domain superfamily TOT_030000492 eb83e715b65c3b3893108538611ff378 207 PRINTS PR00926 Mitochondrial carrier protein signature 16 29 5.8E-7 T 01-11-2018 IPR002067 Mitochondrial carrier protein GO:0022857|GO:0055085 TOT_030000492 eb83e715b65c3b3893108538611ff378 207 PRINTS PR00926 Mitochondrial carrier protein signature 29 43 5.8E-7 T 01-11-2018 IPR002067 Mitochondrial carrier protein GO:0022857|GO:0055085 TOT_030000492 eb83e715b65c3b3893108538611ff378 207 PRINTS PR00926 Mitochondrial carrier protein signature 83 103 5.8E-7 T 01-11-2018 IPR002067 Mitochondrial carrier protein GO:0022857|GO:0055085 TOT_010001304 72128ed8e158ea512a992b8c0862e66d 233 Gene3D G3DSA:3.30.1370.10 137 233 7.4E-26 T 01-11-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TOT_010001304 72128ed8e158ea512a992b8c0862e66d 233 SUPERFAMILY SSF54791 138 229 1.61E-19 T 01-11-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TOT_010001304 72128ed8e158ea512a992b8c0862e66d 233 Pfam PF00013 KH domain 159 206 7.0E-5 T 01-11-2018 IPR004088 K Homology domain, type 1 GO:0003723 TOT_010001304 72128ed8e158ea512a992b8c0862e66d 233 SMART SM00322 138 211 1.2E-5 T 01-11-2018 IPR004087 K Homology domain GO:0003676 TOT_020000204 99815e3d021125ef1fb2c13072f1d2e5 561 SMART SM00271 213 274 1.5E-22 T 01-11-2018 IPR001623 DnaJ domain TOT_020000204 99815e3d021125ef1fb2c13072f1d2e5 561 SUPERFAMILY SSF46565 213 310 3.01E-26 T 01-11-2018 IPR036869 Chaperone J-domain superfamily TOT_020000204 99815e3d021125ef1fb2c13072f1d2e5 561 Gene3D G3DSA:1.10.287.110 211 312 5.6E-25 T 01-11-2018 IPR036869 Chaperone J-domain superfamily TOT_020000204 99815e3d021125ef1fb2c13072f1d2e5 561 ProSitePatterns PS00636 Nt-dnaJ domain signature. 259 278 - T 01-11-2018 IPR018253 DnaJ domain, conserved site TOT_020000204 99815e3d021125ef1fb2c13072f1d2e5 561 Pfam PF00226 DnaJ domain 215 279 1.1E-21 T 01-11-2018 IPR001623 DnaJ domain TOT_020000204 99815e3d021125ef1fb2c13072f1d2e5 561 Pfam PF14308 X-domain of DnaJ-containing 339 523 2.9E-46 T 01-11-2018 IPR026894 DNAJ-containing protein, X-domain TOT_020000204 99815e3d021125ef1fb2c13072f1d2e5 561 PRINTS PR00625 DnaJ domain signature 254 274 7.0E-17 T 01-11-2018 IPR001623 DnaJ domain TOT_020000204 99815e3d021125ef1fb2c13072f1d2e5 561 PRINTS PR00625 DnaJ domain signature 234 249 7.0E-17 T 01-11-2018 IPR001623 DnaJ domain TOT_020000204 99815e3d021125ef1fb2c13072f1d2e5 561 PRINTS PR00625 DnaJ domain signature 216 234 7.0E-17 T 01-11-2018 IPR001623 DnaJ domain TOT_020000204 99815e3d021125ef1fb2c13072f1d2e5 561 PRINTS PR00625 DnaJ domain signature 274 293 7.0E-17 T 01-11-2018 IPR001623 DnaJ domain TOT_020000071 60caea26e6877b65a21d7230726f8252 579 SUPERFAMILY SSF90229 519 549 4.58E-7 T 01-11-2018 IPR036855 Zinc finger, CCCH-type superfamily GO:0046872 TOT_020000071 60caea26e6877b65a21d7230726f8252 579 SUPERFAMILY SSF90229 485 514 3.61E-5 T 01-11-2018 IPR036855 Zinc finger, CCCH-type superfamily GO:0046872 TOT_020000071 60caea26e6877b65a21d7230726f8252 579 Pfam PF00642 Zinc finger C-x8-C-x5-C-x3-H type (and similar) 486 510 1.3E-6 T 01-11-2018 IPR000571 Zinc finger, CCCH-type GO:0046872 TOT_020000071 60caea26e6877b65a21d7230726f8252 579 SMART SM00356 519 545 0.0059 T 01-11-2018 IPR000571 Zinc finger, CCCH-type GO:0046872 TOT_020000071 60caea26e6877b65a21d7230726f8252 579 SMART SM00356 485 510 0.0012 T 01-11-2018 IPR000571 Zinc finger, CCCH-type GO:0046872 TOT_020000071 60caea26e6877b65a21d7230726f8252 579 Gene3D G3DSA:4.10.1000.10 518 552 2.5E-9 T 01-11-2018 TOT_020000071 60caea26e6877b65a21d7230726f8252 579 Gene3D G3DSA:4.10.1000.10 484 516 2.0E-7 T 01-11-2018 TOT_030000806 99004ed5d6e6bfa4cb7e4eafbb4034ca 1558 Pfam PF07496 CW-type Zinc Finger 431 476 4.3E-16 T 01-11-2018 IPR011124 Zinc finger, CW-type GO:0008270 TOT_030000806 99004ed5d6e6bfa4cb7e4eafbb4034ca 1558 Gene3D G3DSA:3.30.40.100 419 481 1.1E-17 T 01-11-2018 TOT_010000746 96f2c67d993849cbd8e8a0b41e3fae9e 469 Pfam PF09751 Nuclear protein Es2 186 430 1.0E-8 T 01-11-2018 IPR019148 Nuclear protein DGCR14/ESS-2 GO:0005634 TOT_010000746 96f2c67d993849cbd8e8a0b41e3fae9e 469 Pfam PF09751 Nuclear protein Es2 108 157 1.8E-8 T 01-11-2018 IPR019148 Nuclear protein DGCR14/ESS-2 GO:0005634 TOT_030000257 1f51ba3864da8d6cdd75d944fa932616 110 PRINTS PR00050 Cold shock protein signature 6 21 7.8E-12 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TOT_030000257 1f51ba3864da8d6cdd75d944fa932616 110 PRINTS PR00050 Cold shock protein signature 41 59 7.8E-12 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TOT_030000257 1f51ba3864da8d6cdd75d944fa932616 110 PRINTS PR00050 Cold shock protein signature 26 35 7.8E-12 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TOT_030000257 1f51ba3864da8d6cdd75d944fa932616 110 Gene3D G3DSA:2.40.50.140 1 79 1.4E-27 T 01-11-2018 TOT_030000257 1f51ba3864da8d6cdd75d944fa932616 110 SMART SM00357 5 68 2.2E-22 T 01-11-2018 IPR011129 Cold shock domain GO:0003676 TOT_030000257 1f51ba3864da8d6cdd75d944fa932616 110 Pfam PF00313 'Cold-shock' DNA-binding domain 5 67 4.5E-23 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TOT_030000257 1f51ba3864da8d6cdd75d944fa932616 110 ProSitePatterns PS00352 'Cold-shock' domain signature. 17 35 - T 01-11-2018 IPR019844 Cold-shock conserved site TOT_030000257 1f51ba3864da8d6cdd75d944fa932616 110 SUPERFAMILY SSF50249 3 67 9.19E-20 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold TOT_030000929 18834c5ebe6f3a6eaf415d67a20c37f0 269 SMART SM00948 8 30 7.0E-10 T 01-11-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TOT_030000929 18834c5ebe6f3a6eaf415d67a20c37f0 269 Gene3D G3DSA:3.60.20.10 1 269 3.2E-64 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TOT_030000929 18834c5ebe6f3a6eaf415d67a20c37f0 269 SUPERFAMILY SSF56235 4 259 2.85E-57 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TOT_030000929 18834c5ebe6f3a6eaf415d67a20c37f0 269 Pfam PF00227 Proteasome subunit 32 236 2.5E-32 T 01-11-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TOT_030000929 18834c5ebe6f3a6eaf415d67a20c37f0 269 ProSitePatterns PS00388 Proteasome alpha-type subunits signature. 8 30 - T 01-11-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TOT_030000929 18834c5ebe6f3a6eaf415d67a20c37f0 269 Pfam PF10584 Proteasome subunit A N-terminal signature 8 30 8.5E-14 T 01-11-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TOT_030000252 232617ab89732b6b77809e770e39ab31 174 Pfam PF04042 DNA polymerase alpha/epsilon subunit B 2 110 1.5E-7 T 01-11-2018 IPR007185 DNA polymerase alpha/epsilon, subunit B GO:0003677|GO:0003887|GO:0006260 TOT_010000408 8614ea9c547c285b93748beaf7a43f5a 3059 SUPERFAMILY SSF48371 67 943 3.32E-9 T 01-11-2018 IPR016024 Armadillo-type fold TOT_010000408 8614ea9c547c285b93748beaf7a43f5a 3059 Pfam PF04118 Dopey, N-terminal 18 303 6.1E-89 T 01-11-2018 IPR007249 Dopey, N-terminal TOT_030000147 193e3d91825c631be99b233cc0f4dc8c 550 Gene3D G3DSA:3.50.7.10 234 386 5.1E-177 T 01-11-2018 IPR027409 GroEL-like apical domain superfamily TOT_030000147 193e3d91825c631be99b233cc0f4dc8c 550 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 40 56 6.9E-23 T 01-11-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TOT_030000147 193e3d91825c631be99b233cc0f4dc8c 550 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 98 117 6.9E-23 T 01-11-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TOT_030000147 193e3d91825c631be99b233cc0f4dc8c 550 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 424 436 6.9E-23 T 01-11-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TOT_030000147 193e3d91825c631be99b233cc0f4dc8c 550 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 390 412 6.9E-23 T 01-11-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TOT_030000147 193e3d91825c631be99b233cc0f4dc8c 550 SUPERFAMILY SSF54849 164 423 7.32E-25 T 01-11-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TOT_030000147 193e3d91825c631be99b233cc0f4dc8c 550 TIGRFAM TIGR02341 chap_CCT_beta: T-complex protein 1, beta subunit 14 546 6.3E-229 T 01-11-2018 IPR012716 T-complex protein 1, beta subunit GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-5620922|Reactome: R-HSA-6798695|Reactome: R-HSA-6814122 TOT_030000147 193e3d91825c631be99b233cc0f4dc8c 550 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 70 86 - T 01-11-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TOT_030000147 193e3d91825c631be99b233cc0f4dc8c 550 Gene3D G3DSA:3.30.260.10 154 422 5.1E-177 T 01-11-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TOT_030000147 193e3d91825c631be99b233cc0f4dc8c 550 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 43 55 - T 01-11-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TOT_030000147 193e3d91825c631be99b233cc0f4dc8c 550 Pfam PF00118 TCP-1/cpn60 chaperonin family 40 541 4.2E-147 T 01-11-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 TOT_030000147 193e3d91825c631be99b233cc0f4dc8c 550 SUPERFAMILY SSF48592 21 542 1.7E-75 T 01-11-2018 IPR027413 GroEL-like equatorial domain superfamily TOT_030000147 193e3d91825c631be99b233cc0f4dc8c 550 Gene3D G3DSA:1.10.560.10 37 539 5.1E-177 T 01-11-2018 IPR027413 GroEL-like equatorial domain superfamily TOT_030000147 193e3d91825c631be99b233cc0f4dc8c 550 SUPERFAMILY SSF52029 229 395 2.01E-43 T 01-11-2018 IPR027409 GroEL-like apical domain superfamily TOT_030000152 d15e1cf9b4490feb11754e3a8eeceabe 374 SUPERFAMILY SSF75689 97 128 1.44E-5 T 01-11-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TOT_030000152 d15e1cf9b4490feb11754e3a8eeceabe 374 SUPERFAMILY SSF100966 4 100 9.81E-24 T 01-11-2018 IPR016189 Translation initiation factor IF2/IF5, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TOT_030000152 d15e1cf9b4490feb11754e3a8eeceabe 374 Gene3D G3DSA:3.30.30.50 24 99 1.4E-28 T 01-11-2018 TOT_030000152 d15e1cf9b4490feb11754e3a8eeceabe 374 Pfam PF01873 Domain found in IF2B/IF5 9 127 1.4E-34 T 01-11-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TOT_030000152 d15e1cf9b4490feb11754e3a8eeceabe 374 SUPERFAMILY SSF48371 237 374 6.91E-6 T 01-11-2018 IPR016024 Armadillo-type fold TOT_030000152 d15e1cf9b4490feb11754e3a8eeceabe 374 Gene3D G3DSA:2.20.25.350 100 143 8.6E-15 T 01-11-2018 TOT_030000152 d15e1cf9b4490feb11754e3a8eeceabe 374 Gene3D G3DSA:1.25.40.180 225 374 6.8E-11 T 01-11-2018 IPR016021 MIF4G-like domain superfamily TOT_030000152 d15e1cf9b4490feb11754e3a8eeceabe 374 SMART SM00653 14 127 3.0E-41 T 01-11-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TOT_010000571 70db42133a4f556f813b17b0abbb4c81 1145 Pfam PF04385 Domain of unknown function, DUF529 1042 1090 2.4E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000317 7dfc4c9cf7ab551bb57fee4f4a8a4ede 613 Gene3D G3DSA:3.30.40.10 8 82 1.2E-22 T 01-11-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type TOT_010000317 7dfc4c9cf7ab551bb57fee4f4a8a4ede 613 Pfam PF14570 RING/Ubox like zinc-binding domain 19 66 1.0E-19 T 01-11-2018 TOT_010000317 7dfc4c9cf7ab551bb57fee4f4a8a4ede 613 SUPERFAMILY SSF54928 129 215 1.49E-13 T 01-11-2018 IPR035979 RNA-binding domain superfamily GO:0003676 TOT_010000317 7dfc4c9cf7ab551bb57fee4f4a8a4ede 613 SMART SM00361 136 216 8.5E-11 T 01-11-2018 IPR003954 RNA recognition motif domain, eukaryote GO:0003676 TOT_010000317 7dfc4c9cf7ab551bb57fee4f4a8a4ede 613 Gene3D G3DSA:3.30.70.330 136 217 8.6E-25 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_010000317 7dfc4c9cf7ab551bb57fee4f4a8a4ede 613 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 155 214 5.7E-5 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_010000317 7dfc4c9cf7ab551bb57fee4f4a8a4ede 613 SUPERFAMILY SSF57850 14 75 5.44E-17 T 01-11-2018 TOT_030000085 8c3c356f1d251bf2b49209a7de37b2a2 915 SUPERFAMILY SSF56104 519 912 6.54E-39 T 01-11-2018 TOT_030000085 8c3c356f1d251bf2b49209a7de37b2a2 915 SUPERFAMILY SSF52768 25 444 2.3E-91 T 01-11-2018 IPR023696 Ureohydrolase domain superfamily TOT_030000085 8c3c356f1d251bf2b49209a7de37b2a2 915 Gene3D G3DSA:3.40.800.20 11 155 3.0E-9 T 01-11-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TOT_030000085 8c3c356f1d251bf2b49209a7de37b2a2 915 Gene3D G3DSA:1.10.510.50 675 915 6.0E-36 T 01-11-2018 IPR038286 Inositol polyphosphate kinase superfamily TOT_030000085 8c3c356f1d251bf2b49209a7de37b2a2 915 Gene3D G3DSA:3.40.800.20 178 468 6.4E-98 T 01-11-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TOT_030000085 8c3c356f1d251bf2b49209a7de37b2a2 915 Pfam PF03770 Inositol polyphosphate kinase 734 910 2.7E-34 T 01-11-2018 IPR005522 Inositol polyphosphate kinase GO:0016301|GO:0032958 TOT_030000085 8c3c356f1d251bf2b49209a7de37b2a2 915 PRINTS PR01270 Histone deacetylase superfamily signature 236 259 2.6E-15 T 01-11-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TOT_030000085 8c3c356f1d251bf2b49209a7de37b2a2 915 PRINTS PR01270 Histone deacetylase superfamily signature 270 285 2.6E-15 T 01-11-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TOT_030000085 8c3c356f1d251bf2b49209a7de37b2a2 915 PRINTS PR01270 Histone deacetylase superfamily signature 359 369 2.6E-15 T 01-11-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TOT_030000085 8c3c356f1d251bf2b49209a7de37b2a2 915 Pfam PF00850 Histone deacetylase domain 32 429 3.0E-98 T 01-11-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TOT_030000117 9d7890f540b6771cd68275900d657d00 411 Gene3D G3DSA:1.20.1540.10 138 246 1.2E-14 T 01-11-2018 IPR035952 Rhomboid-like superfamily TOT_030000117 9d7890f540b6771cd68275900d657d00 411 SUPERFAMILY SSF144091 140 407 1.83E-21 T 01-11-2018 TOT_030000117 9d7890f540b6771cd68275900d657d00 411 Gene3D G3DSA:1.20.1540.10 325 411 1.5E-5 T 01-11-2018 IPR035952 Rhomboid-like superfamily TOT_030000117 9d7890f540b6771cd68275900d657d00 411 Pfam PF01694 Rhomboid family 337 410 5.2E-5 T 01-11-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 TOT_030000117 9d7890f540b6771cd68275900d657d00 411 Pfam PF01694 Rhomboid family 174 237 3.8E-11 T 01-11-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 TOT_010000559 034ad761ab80ed9e906ef3733de87b39 463 Gene3D G3DSA:3.30.70.330 226 333 4.3E-18 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_010000559 034ad761ab80ed9e906ef3733de87b39 463 SUPERFAMILY SSF54928 231 440 7.51E-14 T 01-11-2018 IPR035979 RNA-binding domain superfamily GO:0003676 TOT_010000559 034ad761ab80ed9e906ef3733de87b39 463 SMART SM00360 232 313 0.0033 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_010000559 034ad761ab80ed9e906ef3733de87b39 463 Gene3D G3DSA:3.30.70.330 348 448 3.5E-14 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_020000073 4af81779dfdb02577bd8464f491d154c 160 Pfam PF01157 Ribosomal protein L21e 3 99 2.3E-39 T 01-11-2018 IPR001147 Ribosomal protein L21e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_020000073 4af81779dfdb02577bd8464f491d154c 160 Gene3D G3DSA:2.30.30.70 1 98 3.5E-39 T 01-11-2018 IPR036948 Ribosomal protein L21 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_020000073 4af81779dfdb02577bd8464f491d154c 160 ProSitePatterns PS01171 Ribosomal protein L21e signature. 37 62 - T 01-11-2018 IPR018259 Ribosomal protein L21e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_020000073 4af81779dfdb02577bd8464f491d154c 160 SUPERFAMILY SSF50104 2 99 2.38E-32 T 01-11-2018 IPR008991 Translation protein SH3-like domain superfamily TOT_030000949 9beba35857f12907163bfc0a000d070a 128 SUPERFAMILY SSF49764 2 108 1.57E-16 T 01-11-2018 IPR008978 HSP20-like chaperone TOT_030000949 9beba35857f12907163bfc0a000d070a 128 Gene3D G3DSA:2.60.40.790 1 107 3.0E-19 T 01-11-2018 IPR008978 HSP20-like chaperone TOT_030000949 9beba35857f12907163bfc0a000d070a 128 Pfam PF04969 CS domain 2 66 6.6E-9 T 01-11-2018 IPR007052 CS domain TOT_040000603 7d7b43739fdc3fba61cdf5d276cac97c 921 Pfam PF16381 Coatomer subunit gamma-1 C-terminal appendage platform 811 918 4.6E-13 T 01-11-2018 IPR032154 Coatomer subunit gamma, C-terminal Reactome: R-HSA-6807878|Reactome: R-HSA-6811434 TOT_040000603 7d7b43739fdc3fba61cdf5d276cac97c 921 PIRSF PIRSF037093 9 921 1.4E-182 T 01-11-2018 IPR017106 Coatomer gamma subunit Reactome: R-HSA-6807878|Reactome: R-HSA-6811434 TOT_040000603 7d7b43739fdc3fba61cdf5d276cac97c 921 Pfam PF08752 Coatomer gamma subunit appendage platform subdomain 685 806 4.9E-15 T 01-11-2018 IPR013040 Coatomer, gamma subunit, appendage, Ig-like subdomain GO:0005198|GO:0006886|GO:0016192|GO:0030126 Reactome: R-HSA-6807878|Reactome: R-HSA-6811434 TOT_040000603 7d7b43739fdc3fba61cdf5d276cac97c 921 Pfam PF01602 Adaptin N terminal region 25 532 5.3E-62 T 01-11-2018 IPR002553 Clathrin/coatomer adaptor, adaptin-like, N-terminal GO:0006886|GO:0016192|GO:0030117 TOT_040000603 7d7b43739fdc3fba61cdf5d276cac97c 921 SUPERFAMILY SSF48371 20 535 1.09E-61 T 01-11-2018 IPR016024 Armadillo-type fold TOT_040000603 7d7b43739fdc3fba61cdf5d276cac97c 921 SUPERFAMILY SSF49348 684 808 1.41E-19 T 01-11-2018 IPR013041 Clathrin adaptor, appendage, Ig-like subdomain superfamily TOT_040000603 7d7b43739fdc3fba61cdf5d276cac97c 921 Gene3D G3DSA:2.60.40.1480 672 807 5.9E-16 T 01-11-2018 IPR037067 Coatomer, gamma subunit, appendage domain superfamily GO:0005198|GO:0006886|GO:0016192|GO:0030126 Reactome: R-HSA-6807878|Reactome: R-HSA-6811434 TOT_040000603 7d7b43739fdc3fba61cdf5d276cac97c 921 Gene3D G3DSA:3.30.310.10 810 920 1.5E-8 T 01-11-2018 IPR012295 TBP domain superfamily TOT_040000603 7d7b43739fdc3fba61cdf5d276cac97c 921 SUPERFAMILY SSF55711 821 919 2.35E-10 T 01-11-2018 IPR009028 Coatomer/calthrin adaptor appendage, C-terminal subdomain GO:0006886|GO:0016192|GO:0030117 TOT_040000603 7d7b43739fdc3fba61cdf5d276cac97c 921 Gene3D G3DSA:1.25.10.10 21 312 1.7E-63 T 01-11-2018 IPR011989 Armadillo-like helical TOT_020000721 09d83bf6523ab6542bc01318c744e352 1518 Gene3D G3DSA:3.40.50.300 497 724 7.6E-33 T 01-11-2018 TOT_020000721 09d83bf6523ab6542bc01318c744e352 1518 Gene3D G3DSA:3.40.50.300 1222 1513 2.9E-42 T 01-11-2018 TOT_020000721 09d83bf6523ab6542bc01318c744e352 1518 SUPERFAMILY SSF52540 1167 1505 1.54E-26 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000721 09d83bf6523ab6542bc01318c744e352 1518 Gene3D G3DSA:1.20.1560.10 818 1156 1.7E-12 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000721 09d83bf6523ab6542bc01318c744e352 1518 SUPERFAMILY SSF90123 831 1152 1.11E-24 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000721 09d83bf6523ab6542bc01318c744e352 1518 ProSitePatterns PS00211 ABC transporters family signature. 643 657 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_020000721 09d83bf6523ab6542bc01318c744e352 1518 Pfam PF00664 ABC transporter transmembrane region 858 1116 1.3E-6 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TOT_020000721 09d83bf6523ab6542bc01318c744e352 1518 Pfam PF00005 ABC transporter 531 658 1.3E-12 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000721 09d83bf6523ab6542bc01318c744e352 1518 Pfam PF00005 ABC transporter 1251 1435 1.4E-16 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000721 09d83bf6523ab6542bc01318c744e352 1518 SUPERFAMILY SSF52540 524 713 5.32E-22 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_050000010 308b9d321c1cb9a4bb0aa1e8a323a4b0 162 Pfam PF07724 AAA domain (Cdc48 subfamily) 1 65 8.5E-9 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TOT_050000010 308b9d321c1cb9a4bb0aa1e8a323a4b0 162 SUPERFAMILY SSF52540 1 127 5.76E-9 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_050000010 308b9d321c1cb9a4bb0aa1e8a323a4b0 162 Gene3D G3DSA:3.40.50.300 1 71 1.4E-13 T 01-11-2018 TOT_020000188 ab0907cf931741fabc1117b8d0c9b223 182 SUPERFAMILY SSF52540 7 173 3.82E-17 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000188 ab0907cf931741fabc1117b8d0c9b223 182 Pfam PF13238 AAA domain 9 142 1.5E-23 T 01-11-2018 TOT_020000188 ab0907cf931741fabc1117b8d0c9b223 182 Gene3D G3DSA:3.40.50.300 1 179 1.2E-45 T 01-11-2018 TOT_020000188 ab0907cf931741fabc1117b8d0c9b223 182 Hamap MF_00039 Putative adenylate kinase. 7 181 21.796 T 01-11-2018 IPR020618 Adenylate kinase isoenzyme 6 GO:0004017|GO:0005524 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TOT_010001145 599e72082441023d3200a247872a6942 212 SMART SM00173 8 175 5.5E-21 T 01-11-2018 TOT_010001145 599e72082441023d3200a247872a6942 212 SUPERFAMILY SSF52540 6 180 6.47E-58 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010001145 599e72082441023d3200a247872a6942 212 SMART SM00175 11 175 7.9E-96 T 01-11-2018 TOT_010001145 599e72082441023d3200a247872a6942 212 SMART SM00176 16 208 9.2E-5 T 01-11-2018 TOT_010001145 599e72082441023d3200a247872a6942 212 SMART SM00174 13 175 3.6E-9 T 01-11-2018 TOT_010001145 599e72082441023d3200a247872a6942 212 Gene3D G3DSA:3.40.50.300 4 212 7.6E-67 T 01-11-2018 TOT_010001145 599e72082441023d3200a247872a6942 212 PRINTS PR00449 Transforming protein P21 ras signature 34 50 9.6E-37 T 01-11-2018 TOT_010001145 599e72082441023d3200a247872a6942 212 PRINTS PR00449 Transforming protein P21 ras signature 53 75 9.6E-37 T 01-11-2018 TOT_010001145 599e72082441023d3200a247872a6942 212 PRINTS PR00449 Transforming protein P21 ras signature 115 128 9.6E-37 T 01-11-2018 TOT_010001145 599e72082441023d3200a247872a6942 212 PRINTS PR00449 Transforming protein P21 ras signature 150 172 9.6E-37 T 01-11-2018 TOT_010001145 599e72082441023d3200a247872a6942 212 PRINTS PR00449 Transforming protein P21 ras signature 11 32 9.6E-37 T 01-11-2018 TOT_010001145 599e72082441023d3200a247872a6942 212 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 167 1.5E-34 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TOT_010001145 599e72082441023d3200a247872a6942 212 Pfam PF00071 Ras family 12 172 2.6E-57 T 01-11-2018 IPR001806 Small GTPase GO:0003924|GO:0005525 TOT_010000024 9b35e854b9212cded6767ee052f22cf5 354 ProSitePatterns PS00446 RNA polymerases D / 30 to 40 Kd subunits signature. 35 75 - T 01-11-2018 IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 TOT_010000024 9b35e854b9212cded6767ee052f22cf5 354 SMART SM00662 21 320 3.8E-52 T 01-11-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_010000024 9b35e854b9212cded6767ee052f22cf5 354 Gene3D G3DSA:2.170.120.12 47 182 1.4E-66 T 01-11-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_010000024 9b35e854b9212cded6767ee052f22cf5 354 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 53 184 1.8E-22 T 01-11-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_010000024 9b35e854b9212cded6767ee052f22cf5 354 Gene3D G3DSA:3.30.1360.270 11 313 1.4E-66 T 01-11-2018 TOT_010000024 9b35e854b9212cded6767ee052f22cf5 354 SUPERFAMILY SSF56553 46 185 2.62E-36 T 01-11-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_010000024 9b35e854b9212cded6767ee052f22cf5 354 SUPERFAMILY SSF55257 10 321 1.0E-29 T 01-11-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_010000024 9b35e854b9212cded6767ee052f22cf5 354 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 314 9.9E-18 T 01-11-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOT_010000465 8d5b082e961cf66a354d125b8a86e49c 1526 SUPERFAMILY SSF52540 527 719 1.05E-21 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010000465 8d5b082e961cf66a354d125b8a86e49c 1526 SUPERFAMILY SSF90123 835 1152 1.05E-17 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_010000465 8d5b082e961cf66a354d125b8a86e49c 1526 Pfam PF00005 ABC transporter 534 661 8.0E-13 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_010000465 8d5b082e961cf66a354d125b8a86e49c 1526 SMART SM00382 1264 1438 0.0023 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_010000465 8d5b082e961cf66a354d125b8a86e49c 1526 SMART SM00382 543 743 1.5 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_010000465 8d5b082e961cf66a354d125b8a86e49c 1526 SUPERFAMILY SSF52540 1214 1506 2.44E-27 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010000465 8d5b082e961cf66a354d125b8a86e49c 1526 SUPERFAMILY SSF90123 124 468 8.24E-9 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_010000465 8d5b082e961cf66a354d125b8a86e49c 1526 Gene3D G3DSA:3.40.50.300 502 781 1.7E-33 T 01-11-2018 TOT_010000465 8d5b082e961cf66a354d125b8a86e49c 1526 ProSitePatterns PS00211 ABC transporters family signature. 646 660 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_010000465 8d5b082e961cf66a354d125b8a86e49c 1526 Pfam PF00005 ABC transporter 1255 1361 1.7E-17 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_040000734 264c923822ec7c802583a0016b17b478 780 Pfam PF12246 Temperature dependent protein affecting M2 dsRNA replication 521 764 8.6E-33 T 01-11-2018 IPR022039 Temperature dependent protein affecting M2 dsRNA replication, C-terminal TOT_040000734 264c923822ec7c802583a0016b17b478 780 Pfam PF12247 Temperature dependent protein affecting M2 dsRNA replication 343 428 7.4E-20 T 01-11-2018 IPR022040 Temperature dependent protein affecting M2 dsRNA replication, N-terminal TOT_040000734 264c923822ec7c802583a0016b17b478 780 Pfam PF00867 XPG I-region 153 233 3.0E-7 T 01-11-2018 IPR006086 XPG-I domain GO:0004518 TOT_040000734 264c923822ec7c802583a0016b17b478 780 Gene3D G3DSA:3.40.50.1010 3 287 8.5E-18 T 01-11-2018 TOT_040000734 264c923822ec7c802583a0016b17b478 780 SMART SM00484 151 219 0.0027 T 01-11-2018 IPR006086 XPG-I domain GO:0004518 TOT_040000734 264c923822ec7c802583a0016b17b478 780 SUPERFAMILY SSF88723 4 234 2.98E-24 T 01-11-2018 IPR029060 PIN-like domain superfamily TOT_030000020 653c539707133cf7d05569d75ec4d616 1300 Pfam PF04385 Domain of unknown function, DUF529 673 724 5.1E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000815 d619c4081e69cbead8601fea4ed9718f 1967 SMART SM00487 837 1037 4.8E-35 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOT_010000815 d619c4081e69cbead8601fea4ed9718f 1967 Pfam PF00385 Chromo (CHRromatin Organisation MOdifier) domain 460 512 2.3E-9 T 01-11-2018 IPR023780 Chromo domain TOT_010000815 d619c4081e69cbead8601fea4ed9718f 1967 Pfam PF00385 Chromo (CHRromatin Organisation MOdifier) domain 546 596 1.4E-11 T 01-11-2018 IPR023780 Chromo domain TOT_010000815 d619c4081e69cbead8601fea4ed9718f 1967 Gene3D G3DSA:2.40.50.40 537 596 1.7E-13 T 01-11-2018 TOT_010000815 d619c4081e69cbead8601fea4ed9718f 1967 Gene3D G3DSA:2.40.50.40 437 513 2.9E-16 T 01-11-2018 TOT_010000815 d619c4081e69cbead8601fea4ed9718f 1967 Gene3D G3DSA:3.40.50.10810 837 1081 3.0E-179 T 01-11-2018 IPR038718 SNF2-like, N-terminal domain superfamily TOT_010000815 d619c4081e69cbead8601fea4ed9718f 1967 SUPERFAMILY SSF52540 1074 1340 3.73E-72 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010000815 d619c4081e69cbead8601fea4ed9718f 1967 Pfam PF00176 SNF2 family N-terminal domain 838 1139 3.8E-60 T 01-11-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 TOT_010000815 d619c4081e69cbead8601fea4ed9718f 1967 SUPERFAMILY SSF54160 523 596 4.95E-14 T 01-11-2018 IPR016197 Chromo-like domain superfamily TOT_010000815 d619c4081e69cbead8601fea4ed9718f 1967 Pfam PF00271 Helicase conserved C-terminal domain 1162 1272 1.2E-20 T 01-11-2018 IPR001650 Helicase, C-terminal TOT_010000815 d619c4081e69cbead8601fea4ed9718f 1967 SMART SM00298 543 600 6.3E-9 T 01-11-2018 IPR000953 Chromo/chromo shadow domain TOT_010000815 d619c4081e69cbead8601fea4ed9718f 1967 SMART SM00298 457 513 1.3E-11 T 01-11-2018 IPR000953 Chromo/chromo shadow domain TOT_010000815 d619c4081e69cbead8601fea4ed9718f 1967 SUPERFAMILY SSF54160 459 513 5.68E-17 T 01-11-2018 IPR016197 Chromo-like domain superfamily TOT_010000815 d619c4081e69cbead8601fea4ed9718f 1967 Gene3D G3DSA:3.40.50.300 1082 1303 3.0E-179 T 01-11-2018 TOT_010000815 d619c4081e69cbead8601fea4ed9718f 1967 SMART SM00490 1188 1272 3.6E-26 T 01-11-2018 IPR001650 Helicase, C-terminal TOT_010000815 d619c4081e69cbead8601fea4ed9718f 1967 Gene3D G3DSA:1.10.10.60 1577 1688 4.0E-8 T 01-11-2018 TOT_010000815 d619c4081e69cbead8601fea4ed9718f 1967 SUPERFAMILY SSF52540 840 1072 5.69E-52 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000129 576cd51ce1b7e3459c84862edfa07bd3 301 PRINTS PR00926 Mitochondrial carrier protein signature 74 94 3.6E-66 T 01-11-2018 IPR002067 Mitochondrial carrier protein GO:0022857|GO:0055085 TOT_020000129 576cd51ce1b7e3459c84862edfa07bd3 301 PRINTS PR00926 Mitochondrial carrier protein signature 23 37 3.6E-66 T 01-11-2018 IPR002067 Mitochondrial carrier protein GO:0022857|GO:0055085 TOT_020000129 576cd51ce1b7e3459c84862edfa07bd3 301 PRINTS PR00926 Mitochondrial carrier protein signature 10 23 3.6E-66 T 01-11-2018 IPR002067 Mitochondrial carrier protein GO:0022857|GO:0055085 TOT_020000129 576cd51ce1b7e3459c84862edfa07bd3 301 PRINTS PR00926 Mitochondrial carrier protein signature 173 191 3.6E-66 T 01-11-2018 IPR002067 Mitochondrial carrier protein GO:0022857|GO:0055085 TOT_020000129 576cd51ce1b7e3459c84862edfa07bd3 301 PRINTS PR00926 Mitochondrial carrier protein signature 218 240 3.6E-66 T 01-11-2018 IPR002067 Mitochondrial carrier protein GO:0022857|GO:0055085 TOT_020000129 576cd51ce1b7e3459c84862edfa07bd3 301 PRINTS PR00926 Mitochondrial carrier protein signature 126 144 3.6E-66 T 01-11-2018 IPR002067 Mitochondrial carrier protein GO:0022857|GO:0055085 TOT_020000129 576cd51ce1b7e3459c84862edfa07bd3 301 SUPERFAMILY SSF103506 5 295 7.85E-76 T 01-11-2018 IPR023395 Mitochondrial carrier domain superfamily TOT_020000129 576cd51ce1b7e3459c84862edfa07bd3 301 PRINTS PR00927 Adenine nucleotide translocator signature 7 19 6.7E-36 T 01-11-2018 IPR002113 Adenine nucleotide translocator 1 GO:0005743|GO:0022857|GO:0055085 TOT_020000129 576cd51ce1b7e3459c84862edfa07bd3 301 PRINTS PR00927 Adenine nucleotide translocator signature 214 230 6.7E-36 T 01-11-2018 IPR002113 Adenine nucleotide translocator 1 GO:0005743|GO:0022857|GO:0055085 TOT_020000129 576cd51ce1b7e3459c84862edfa07bd3 301 PRINTS PR00927 Adenine nucleotide translocator signature 52 73 6.7E-36 T 01-11-2018 IPR002113 Adenine nucleotide translocator 1 GO:0005743|GO:0022857|GO:0055085 TOT_020000129 576cd51ce1b7e3459c84862edfa07bd3 301 PRINTS PR00927 Adenine nucleotide translocator signature 111 124 6.7E-36 T 01-11-2018 IPR002113 Adenine nucleotide translocator 1 GO:0005743|GO:0022857|GO:0055085 TOT_020000129 576cd51ce1b7e3459c84862edfa07bd3 301 PRINTS PR00927 Adenine nucleotide translocator signature 85 97 6.7E-36 T 01-11-2018 IPR002113 Adenine nucleotide translocator 1 GO:0005743|GO:0022857|GO:0055085 TOT_020000129 576cd51ce1b7e3459c84862edfa07bd3 301 Pfam PF00153 Mitochondrial carrier protein 111 203 2.0E-24 T 01-11-2018 IPR018108 Mitochondrial substrate/solute carrier TOT_020000129 576cd51ce1b7e3459c84862edfa07bd3 301 Pfam PF00153 Mitochondrial carrier protein 5 103 5.4E-23 T 01-11-2018 IPR018108 Mitochondrial substrate/solute carrier TOT_020000129 576cd51ce1b7e3459c84862edfa07bd3 301 Pfam PF00153 Mitochondrial carrier protein 218 300 1.5E-16 T 01-11-2018 IPR018108 Mitochondrial substrate/solute carrier TOT_020000129 576cd51ce1b7e3459c84862edfa07bd3 301 Gene3D G3DSA:1.50.40.10 2 300 1.1E-97 T 01-11-2018 IPR023395 Mitochondrial carrier domain superfamily TOT_030000124 67649de5a48c027cbf14a8373641fce9 329 SUPERFAMILY SSF47576 1 123 2.23E-34 T 01-11-2018 IPR036872 CH domain superfamily TOT_030000124 67649de5a48c027cbf14a8373641fce9 329 Gene3D G3DSA:1.10.418.10 2 124 9.3E-40 T 01-11-2018 IPR036872 CH domain superfamily TOT_030000124 67649de5a48c027cbf14a8373641fce9 329 Pfam PF03271 EB1-like C-terminal motif 294 327 9.0E-9 T 01-11-2018 IPR004953 EB1, C-terminal GO:0008017 TOT_030000124 67649de5a48c027cbf14a8373641fce9 329 SUPERFAMILY SSF140612 272 328 5.1E-13 T 01-11-2018 IPR036133 EB1, C-terminal domain superfamily GO:0008017 TOT_030000124 67649de5a48c027cbf14a8373641fce9 329 Pfam PF00307 Calponin homology (CH) domain 8 100 6.9E-9 T 01-11-2018 IPR001715 Calponin homology domain GO:0005515 TOT_040000571 c9a71fd2146e8d24c99ab2b934eb3419 339 Gene3D G3DSA:3.40.50.720 5 329 1.2E-145 T 01-11-2018 TOT_040000571 c9a71fd2146e8d24c99ab2b934eb3419 339 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 01-11-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TOT_040000571 c9a71fd2146e8d24c99ab2b934eb3419 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 1.1E-44 T 01-11-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TOT_040000571 c9a71fd2146e8d24c99ab2b934eb3419 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 272 287 1.1E-44 T 01-11-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TOT_040000571 c9a71fd2146e8d24c99ab2b934eb3419 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 1.1E-44 T 01-11-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TOT_040000571 c9a71fd2146e8d24c99ab2b934eb3419 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 232 249 1.1E-44 T 01-11-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TOT_040000571 c9a71fd2146e8d24c99ab2b934eb3419 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 1.1E-44 T 01-11-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TOT_040000571 c9a71fd2146e8d24c99ab2b934eb3419 339 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 328 6.6E-125 T 01-11-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TOT_040000571 c9a71fd2146e8d24c99ab2b934eb3419 339 SUPERFAMILY SSF55347 151 316 1.47E-73 T 01-11-2018 TOT_040000571 c9a71fd2146e8d24c99ab2b934eb3419 339 SMART SM00846 3 152 1.7E-79 T 01-11-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TOT_040000571 c9a71fd2146e8d24c99ab2b934eb3419 339 Gene3D G3DSA:3.30.360.10 150 318 1.2E-145 T 01-11-2018 TOT_040000571 c9a71fd2146e8d24c99ab2b934eb3419 339 SUPERFAMILY SSF51735 3 168 3.11E-61 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily TOT_040000571 c9a71fd2146e8d24c99ab2b934eb3419 339 PIRSF PIRSF000149 1 338 3.1E-120 T 01-11-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TOT_040000571 c9a71fd2146e8d24c99ab2b934eb3419 339 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 103 1.6E-34 T 01-11-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TOT_040000571 c9a71fd2146e8d24c99ab2b934eb3419 339 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 316 6.1E-66 T 01-11-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TOT_040000006 e4070ef15563b2d1304bacfd20d8f84d 1526 Gene3D G3DSA:1.20.1560.10 815 1154 7.0E-13 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_040000006 e4070ef15563b2d1304bacfd20d8f84d 1526 Gene3D G3DSA:3.40.50.300 493 765 5.3E-32 T 01-11-2018 TOT_040000006 e4070ef15563b2d1304bacfd20d8f84d 1526 SUPERFAMILY SSF52540 1213 1504 7.99E-26 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_040000006 e4070ef15563b2d1304bacfd20d8f84d 1526 Pfam PF00005 ABC transporter 531 658 1.7E-10 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_040000006 e4070ef15563b2d1304bacfd20d8f84d 1526 ProSitePatterns PS00211 ABC transporters family signature. 643 657 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_040000006 e4070ef15563b2d1304bacfd20d8f84d 1526 Pfam PF00005 ABC transporter 1250 1435 1.2E-17 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_040000006 e4070ef15563b2d1304bacfd20d8f84d 1526 SUPERFAMILY SSF90123 832 1151 1.96E-25 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_040000006 e4070ef15563b2d1304bacfd20d8f84d 1526 SUPERFAMILY SSF52540 524 717 1.06E-21 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000374 e786c09ff253ccc32feb2e4c4e9af083 1237 SMART SM00156 856 1142 8.5E-4 T 01-11-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TOT_020000374 e786c09ff253ccc32feb2e4c4e9af083 1237 Gene3D G3DSA:1.10.238.10 171 371 9.9E-11 T 01-11-2018 TOT_020000374 e786c09ff253ccc32feb2e4c4e9af083 1237 SUPERFAMILY SSF47473 200 342 5.25E-11 T 01-11-2018 IPR011992 EF-hand domain pair TOT_020000374 e786c09ff253ccc32feb2e4c4e9af083 1237 SUPERFAMILY SSF56300 852 1074 1.21E-18 T 01-11-2018 TOT_020000313 a4b243e0b74e751beff60444d794b63a 212 Pfam PF01105 emp24/gp25L/p24 family/GOLD 32 207 1.5E-20 T 01-11-2018 IPR009038 GOLD domain TOT_020000313 a4b243e0b74e751beff60444d794b63a 212 SMART SM01190 30 207 5.5E-16 T 01-11-2018 IPR009038 GOLD domain TOT_010001043 ba148ed012ac1a0ef65a0b73a5f2d038 593 SUPERFAMILY SSF57863 22 118 5.62E-30 T 01-11-2018 IPR037278 ARFGAP/RecO-like zinc finger TOT_010001043 ba148ed012ac1a0ef65a0b73a5f2d038 593 Pfam PF01412 Putative GTPase activating protein for Arf 24 110 4.8E-27 T 01-11-2018 IPR001164 Arf GTPase activating protein GO:0005096 TOT_010001043 ba148ed012ac1a0ef65a0b73a5f2d038 593 Gene3D G3DSA:3.30.40.160 10 150 2.3E-33 T 01-11-2018 IPR038508 ArfGAP domain superfamily TOT_010001043 ba148ed012ac1a0ef65a0b73a5f2d038 593 SMART SM00105 21 147 1.9E-22 T 01-11-2018 IPR001164 Arf GTPase activating protein GO:0005096 TOT_010001043 ba148ed012ac1a0ef65a0b73a5f2d038 593 PRINTS PR00405 HIV Rev interacting protein signature 33 52 3.2E-15 T 01-11-2018 IPR001164 Arf GTPase activating protein GO:0005096 TOT_010001043 ba148ed012ac1a0ef65a0b73a5f2d038 593 PRINTS PR00405 HIV Rev interacting protein signature 73 94 3.2E-15 T 01-11-2018 IPR001164 Arf GTPase activating protein GO:0005096 TOT_010001043 ba148ed012ac1a0ef65a0b73a5f2d038 593 PRINTS PR00405 HIV Rev interacting protein signature 52 69 3.2E-15 T 01-11-2018 IPR001164 Arf GTPase activating protein GO:0005096 TOT_020000534 06b95ff2dd9dbad3ba7a21d10ab023a9 234 Pfam PF04938 Survival motor neuron (SMN) interacting protein 1 (SIP1) 2 233 4.8E-14 T 01-11-2018 IPR035426 Gemin2/Brr1 Reactome: R-HSA-191859 TOT_020000534 06b95ff2dd9dbad3ba7a21d10ab023a9 234 Gene3D G3DSA:1.20.58.1070 142 234 5.5E-5 T 01-11-2018 TOT_030000606 2bcfea80719d75db2869a7e4cae1b68e 2291 Pfam PF02181 Formin Homology 2 Domain 1825 2206 1.0E-20 T 01-11-2018 IPR015425 Formin, FH2 domain TOT_030000606 2bcfea80719d75db2869a7e4cae1b68e 2291 Gene3D G3DSA:3.90.190.10 272 459 1.2E-6 T 01-11-2018 IPR029021 Protein-tyrosine phosphatase-like TOT_030000606 2bcfea80719d75db2869a7e4cae1b68e 2291 SMART SM01326 668 855 0.002 T 01-11-2018 IPR014020 Tensin phosphatase, C2 domain TOT_030000606 2bcfea80719d75db2869a7e4cae1b68e 2291 Gene3D G3DSA:1.20.58.2220 1456 1583 2.1E-8 T 01-11-2018 TOT_030000606 2bcfea80719d75db2869a7e4cae1b68e 2291 SUPERFAMILY SSF101447 1468 1579 6.8E-8 T 01-11-2018 TOT_030000606 2bcfea80719d75db2869a7e4cae1b68e 2291 SUPERFAMILY SSF101447 1547 2253 1.7E-33 T 01-11-2018 TOT_030000606 2bcfea80719d75db2869a7e4cae1b68e 2291 Gene3D G3DSA:1.20.58.2220 1818 1975 3.2E-19 T 01-11-2018 TOT_040000666 154f9f6228e81f48f9547cb33e1ae98a 333 Pfam PF08711 TFIIS helical bundle-like domain 214 254 2.0E-5 T 01-11-2018 IPR017923 Transcription factor IIS, N-terminal GO:0005634 TOT_040000666 154f9f6228e81f48f9547cb33e1ae98a 333 Gene3D G3DSA:1.20.930.10 120 260 1.2E-35 T 01-11-2018 IPR035441 TFIIS/LEDGF domain superfamily TOT_010000450 3229537cf78c83e860f062890dadfa52 322 Gene3D G3DSA:2.40.50.140 132 259 2.3E-45 T 01-11-2018 TOT_010000450 3229537cf78c83e860f062890dadfa52 322 SUPERFAMILY SSF50249 136 251 1.54E-39 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold TOT_010000450 3229537cf78c83e860f062890dadfa52 322 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 141 248 1.4E-40 T 01-11-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TOT_010000450 3229537cf78c83e860f062890dadfa52 322 PRINTS PR01034 Ribosomal protein S12 signature 186 205 4.1E-36 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOT_010000450 3229537cf78c83e860f062890dadfa52 322 PRINTS PR01034 Ribosomal protein S12 signature 170 185 4.1E-36 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOT_010000450 3229537cf78c83e860f062890dadfa52 322 PRINTS PR01034 Ribosomal protein S12 signature 205 222 4.1E-36 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOT_010000450 3229537cf78c83e860f062890dadfa52 322 PRINTS PR01034 Ribosomal protein S12 signature 238 250 4.1E-36 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOT_010000450 3229537cf78c83e860f062890dadfa52 322 PRINTS PR01034 Ribosomal protein S12 signature 155 170 4.1E-36 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOT_010000450 3229537cf78c83e860f062890dadfa52 322 PRINTS PR01034 Ribosomal protein S12 signature 222 238 4.1E-36 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOT_010000450 3229537cf78c83e860f062890dadfa52 322 Pfam PF00164 Ribosomal protein S12/S23 144 246 1.2E-25 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOT_010001206 091cd0c5f3f6d7f41dacdae9f1275200 90 Gene3D G3DSA:3.40.50.2020 3 84 1.1E-15 T 01-11-2018 TOT_010001206 091cd0c5f3f6d7f41dacdae9f1275200 90 SUPERFAMILY SSF53271 14 81 5.83E-8 T 01-11-2018 IPR029057 Phosphoribosyltransferase-like TOT_030000547 cba1a224b5495295defe24e5919e7718 199 SUPERFAMILY SSF102848 36 102 2.35E-18 T 01-11-2018 IPR036241 NSFL1 cofactor p47, SEP domain superfamily TOT_030000547 cba1a224b5495295defe24e5919e7718 199 Pfam PF00789 UBX domain 124 195 2.9E-5 T 01-11-2018 IPR001012 UBX domain GO:0005515 TOT_030000547 cba1a224b5495295defe24e5919e7718 199 SUPERFAMILY SSF54236 123 196 7.84E-12 T 01-11-2018 IPR029071 Ubiquitin-like domain superfamily TOT_030000547 cba1a224b5495295defe24e5919e7718 199 Gene3D G3DSA:3.10.20.90 119 198 1.3E-10 T 01-11-2018 TOT_030000547 cba1a224b5495295defe24e5919e7718 199 Gene3D G3DSA:3.30.420.210 35 93 4.9E-17 T 01-11-2018 IPR036241 NSFL1 cofactor p47, SEP domain superfamily TOT_030000547 cba1a224b5495295defe24e5919e7718 199 Pfam PF08059 SEP domain 39 101 2.7E-18 T 01-11-2018 IPR012989 SEP domain TOT_030000547 cba1a224b5495295defe24e5919e7718 199 SMART SM00553 29 118 0.0013 T 01-11-2018 IPR012989 SEP domain TOT_020001041 9fa07cb7ed9c5afa2541b6ea9758d499 609 SUPERFAMILY SSF52540 201 485 2.6E-53 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020001041 9fa07cb7ed9c5afa2541b6ea9758d499 609 Pfam PF00270 DEAD/DEAH box helicase 147 321 1.3E-33 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TOT_020001041 9fa07cb7ed9c5afa2541b6ea9758d499 609 SMART SM00487 142 349 7.5E-38 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOT_020001041 9fa07cb7ed9c5afa2541b6ea9758d499 609 Pfam PF00271 Helicase conserved C-terminal domain 372 471 1.2E-23 T 01-11-2018 IPR001650 Helicase, C-terminal TOT_020001041 9fa07cb7ed9c5afa2541b6ea9758d499 609 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 279 287 - T 01-11-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site TOT_020001041 9fa07cb7ed9c5afa2541b6ea9758d499 609 Gene3D G3DSA:3.40.50.300 339 575 1.2E-40 T 01-11-2018 TOT_020001041 9fa07cb7ed9c5afa2541b6ea9758d499 609 SMART SM00490 390 471 4.6E-22 T 01-11-2018 IPR001650 Helicase, C-terminal TOT_020001041 9fa07cb7ed9c5afa2541b6ea9758d499 609 Gene3D G3DSA:3.40.50.300 83 337 9.7E-64 T 01-11-2018 TOT_040000506 59ce68ea4c972718453392ed8b670812 760 SUPERFAMILY SSF54928 8 100 1.48E-9 T 01-11-2018 IPR035979 RNA-binding domain superfamily GO:0003676 TOT_040000506 59ce68ea4c972718453392ed8b670812 760 SUPERFAMILY SSF54928 206 478 6.66E-27 T 01-11-2018 IPR035979 RNA-binding domain superfamily GO:0003676 TOT_040000506 59ce68ea4c972718453392ed8b670812 760 Gene3D G3DSA:3.30.70.330 561 671 4.1E-13 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_040000506 59ce68ea4c972718453392ed8b670812 760 SMART SM00360 408 475 1.1E-7 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_040000506 59ce68ea4c972718453392ed8b670812 760 SMART SM00360 209 291 8.0E-15 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_040000506 59ce68ea4c972718453392ed8b670812 760 SMART SM00360 11 95 3.1E-5 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_040000506 59ce68ea4c972718453392ed8b670812 760 SMART SM00360 575 657 7.0E-10 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_040000506 59ce68ea4c972718453392ed8b670812 760 SMART SM00360 682 754 7.0E-20 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_040000506 59ce68ea4c972718453392ed8b670812 760 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 409 472 2.1E-7 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_040000506 59ce68ea4c972718453392ed8b670812 760 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 210 288 5.7E-9 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_040000506 59ce68ea4c972718453392ed8b670812 760 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 683 751 5.0E-17 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_040000506 59ce68ea4c972718453392ed8b670812 760 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 576 654 4.2E-6 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_040000506 59ce68ea4c972718453392ed8b670812 760 Gene3D G3DSA:3.30.70.330 140 330 4.7E-20 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_040000506 59ce68ea4c972718453392ed8b670812 760 Gene3D G3DSA:3.30.70.330 399 503 1.9E-13 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_040000506 59ce68ea4c972718453392ed8b670812 760 Gene3D G3DSA:3.30.70.330 675 760 1.2E-22 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_040000506 59ce68ea4c972718453392ed8b670812 760 SUPERFAMILY SSF54928 575 757 1.83E-32 T 01-11-2018 IPR035979 RNA-binding domain superfamily GO:0003676 TOT_040000506 59ce68ea4c972718453392ed8b670812 760 Gene3D G3DSA:3.30.70.330 6 112 1.7E-10 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_030000699 a754f535c567ac0f31a7d6df54568e70 194 Pfam PF04385 Domain of unknown function, DUF529 38 82 1.9E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000918 bd72bb3b1bea032aafd51a0c11cdb922 1861 Pfam PF11262 Transcription factor/nuclear export subunit protein 2 1315 1848 4.1E-79 T 01-11-2018 IPR021418 THO complex, subunitTHOC2, C-terminal Reactome: R-HSA-109688|Reactome: R-HSA-159236|Reactome: R-HSA-72187 TOT_020000918 bd72bb3b1bea032aafd51a0c11cdb922 1861 Pfam PF16134 THO complex subunit 2 N-terminus 223 496 3.7E-14 T 01-11-2018 IPR032302 THO complex subunit 2, N-terminal domain Reactome: R-HSA-109688|Reactome: R-HSA-159236|Reactome: R-HSA-72187 TOT_020000918 bd72bb3b1bea032aafd51a0c11cdb922 1861 Pfam PF11732 Transcription- and export-related complex subunit 912 961 3.7E-5 T 01-11-2018 IPR021726 THO complex, subunitTHOC2, N-terminal Reactome: R-HSA-109688|Reactome: R-HSA-159236|Reactome: R-HSA-72187 TOT_020000187 c48b0830ad036816384d0f6b60453f06 339 Pfam PF08271 TFIIB zinc-binding 15 56 5.1E-9 T 01-11-2018 IPR013137 Zinc finger, TFIIB-type TOT_020000187 c48b0830ad036816384d0f6b60453f06 339 PRINTS PR00685 Transcription initiation factor IIB signature 185 200 1.7E-24 T 01-11-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TOT_020000187 c48b0830ad036816384d0f6b60453f06 339 PRINTS PR00685 Transcription initiation factor IIB signature 214 232 1.7E-24 T 01-11-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TOT_020000187 c48b0830ad036816384d0f6b60453f06 339 PRINTS PR00685 Transcription initiation factor IIB signature 28 48 1.7E-24 T 01-11-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TOT_020000187 c48b0830ad036816384d0f6b60453f06 339 PRINTS PR00685 Transcription initiation factor IIB signature 247 263 1.7E-24 T 01-11-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TOT_020000187 c48b0830ad036816384d0f6b60453f06 339 PRINTS PR00685 Transcription initiation factor IIB signature 158 177 1.7E-24 T 01-11-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TOT_020000187 c48b0830ad036816384d0f6b60453f06 339 PRINTS PR00685 Transcription initiation factor IIB signature 50 63 1.7E-24 T 01-11-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TOT_020000187 c48b0830ad036816384d0f6b60453f06 339 PRINTS PR00685 Transcription initiation factor IIB signature 67 88 1.7E-24 T 01-11-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TOT_020000187 c48b0830ad036816384d0f6b60453f06 339 SUPERFAMILY SSF47954 117 201 1.96E-9 T 01-11-2018 IPR036915 Cyclin-like superfamily TOT_020000187 c48b0830ad036816384d0f6b60453f06 339 SUPERFAMILY SSF57783 8 59 8.42E-11 T 01-11-2018 TOT_020000187 c48b0830ad036816384d0f6b60453f06 339 Pfam PF00382 Transcription factor TFIIB repeat 120 177 4.6E-5 T 01-11-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 TOT_020000187 c48b0830ad036816384d0f6b60453f06 339 Gene3D G3DSA:1.10.472.170 13 200 5.4E-39 T 01-11-2018 TOT_020000187 c48b0830ad036816384d0f6b60453f06 339 Gene3D G3DSA:1.10.472.10 210 312 3.5E-14 T 01-11-2018 TOT_020000187 c48b0830ad036816384d0f6b60453f06 339 SUPERFAMILY SSF47954 210 307 7.74E-14 T 01-11-2018 IPR036915 Cyclin-like superfamily TOT_040000743 580f2275ed602f158b5adac1a3c9da53 547 Pfam PF03941 Inner centromere protein, ARK binding region 307 345 3.7E-5 T 01-11-2018 IPR005635 Inner centromere protein, ARK-binding domain Reactome: R-HSA-141444|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-4615885|Reactome: R-HSA-5663220|Reactome: R-HSA-68877 TOT_010001288 2a7afd8bcfdbe97b50eb493ab13d6a10 575 SMART SM00931 167 219 9.7E-25 T 01-11-2018 IPR012976 NOSIC TOT_010001288 2a7afd8bcfdbe97b50eb493ab13d6a10 575 Pfam PF08156 NOP5NT (NUC127) domain 5 69 3.6E-18 T 01-11-2018 IPR012974 NOP5, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TOT_010001288 2a7afd8bcfdbe97b50eb493ab13d6a10 575 Pfam PF01798 snoRNA binding domain, fibrillarin 174 408 2.8E-79 T 01-11-2018 IPR002687 Nop domain TOT_010001288 2a7afd8bcfdbe97b50eb493ab13d6a10 575 Gene3D G3DSA:1.10.287.660 168 285 4.5E-40 T 01-11-2018 IPR029012 Helix hairpin bin domain superfamily TOT_010001288 2a7afd8bcfdbe97b50eb493ab13d6a10 575 Gene3D G3DSA:1.10.246.90 286 411 9.4E-47 T 01-11-2018 TOT_010001288 2a7afd8bcfdbe97b50eb493ab13d6a10 575 SUPERFAMILY SSF89124 161 410 1.18E-81 T 01-11-2018 IPR036070 Nop domain superfamily TOT_010001288 2a7afd8bcfdbe97b50eb493ab13d6a10 575 Gene3D G3DSA:1.10.150.460 198 254 4.5E-40 T 01-11-2018 TOT_010001084 e20417cf4b13068bad296b0dec3de442 168 SUPERFAMILY SSF52799 13 158 1.29E-30 T 01-11-2018 IPR029021 Protein-tyrosine phosphatase-like TOT_010001084 e20417cf4b13068bad296b0dec3de442 168 Pfam PF00782 Dual specificity phosphatase, catalytic domain 87 146 3.4E-7 T 01-11-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 TOT_010001084 e20417cf4b13068bad296b0dec3de442 168 Gene3D G3DSA:3.90.190.10 4 162 4.5E-40 T 01-11-2018 IPR029021 Protein-tyrosine phosphatase-like TOT_040000500 9b206279d6dbd3ea0d41d6f1bb358993 1314 Pfam PF02463 RecF/RecN/SMC N terminal domain 792 1239 3.6E-20 T 01-11-2018 IPR003395 RecF/RecN/SMC, N-terminal TOT_040000500 9b206279d6dbd3ea0d41d6f1bb358993 1314 Gene3D G3DSA:3.40.50.300 1100 1259 3.1E-42 T 01-11-2018 TOT_040000500 9b206279d6dbd3ea0d41d6f1bb358993 1314 SUPERFAMILY SSF75553 466 687 2.88E-25 T 01-11-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 TOT_040000500 9b206279d6dbd3ea0d41d6f1bb358993 1314 SUPERFAMILY SSF52540 1 1237 9.87E-39 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_040000500 9b206279d6dbd3ea0d41d6f1bb358993 1314 PIRSF PIRSF005719 1 1237 3.6E-142 T 01-11-2018 IPR024704 Structural maintenance of chromosomes protein TOT_040000500 9b206279d6dbd3ea0d41d6f1bb358993 1314 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 397 6.0E-26 T 01-11-2018 IPR003395 RecF/RecN/SMC, N-terminal TOT_040000500 9b206279d6dbd3ea0d41d6f1bb358993 1314 Gene3D G3DSA:3.40.50.300 1 246 5.3E-45 T 01-11-2018 TOT_040000500 9b206279d6dbd3ea0d41d6f1bb358993 1314 Pfam PF06470 SMC proteins Flexible Hinge Domain 506 635 8.9E-8 T 01-11-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 TOT_040000500 9b206279d6dbd3ea0d41d6f1bb358993 1314 Gene3D G3DSA:1.20.1060.20 505 670 2.4E-13 T 01-11-2018 TOT_040000500 9b206279d6dbd3ea0d41d6f1bb358993 1314 Gene3D G3DSA:3.30.70.1620 569 667 2.4E-13 T 01-11-2018 TOT_020000566 13aa8edbc18a717bdfcb69d0ee44ffd1 203 ProSitePatterns PS00856 Guanylate kinase-like signature. 45 62 - T 01-11-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 TOT_020000566 13aa8edbc18a717bdfcb69d0ee44ffd1 203 Pfam PF00625 Guanylate kinase 13 190 5.9E-49 T 01-11-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit TOT_020000566 13aa8edbc18a717bdfcb69d0ee44ffd1 203 Gene3D G3DSA:3.30.63.10 42 101 3.7E-58 T 01-11-2018 TOT_020000566 13aa8edbc18a717bdfcb69d0ee44ffd1 203 SUPERFAMILY SSF52540 10 192 1.37E-53 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000566 13aa8edbc18a717bdfcb69d0ee44ffd1 203 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 12 188 2.8E-55 T 01-11-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 TOT_020000566 13aa8edbc18a717bdfcb69d0ee44ffd1 203 SMART SM00072 9 194 2.0E-45 T 01-11-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit TOT_020000566 13aa8edbc18a717bdfcb69d0ee44ffd1 203 Gene3D G3DSA:3.40.50.300 13 185 3.7E-58 T 01-11-2018 TOT_020001063 e8bb0afa7bb9cdb9fe3edcf7bec3a448 3445 Pfam PF00027 Cyclic nucleotide-binding domain 3331 3411 1.3E-6 T 01-11-2018 IPR000595 Cyclic nucleotide-binding domain TOT_020001063 e8bb0afa7bb9cdb9fe3edcf7bec3a448 3445 SUPERFAMILY SSF51206 3300 3418 4.19E-14 T 01-11-2018 IPR018490 Cyclic nucleotide-binding-like TOT_020001063 e8bb0afa7bb9cdb9fe3edcf7bec3a448 3445 SMART SM00100 3312 3426 0.17 T 01-11-2018 IPR000595 Cyclic nucleotide-binding domain TOT_020001063 e8bb0afa7bb9cdb9fe3edcf7bec3a448 3445 SMART SM00100 398 517 0.015 T 01-11-2018 IPR000595 Cyclic nucleotide-binding domain TOT_020001063 e8bb0afa7bb9cdb9fe3edcf7bec3a448 3445 SUPERFAMILY SSF47473 2843 2985 1.41E-6 T 01-11-2018 IPR011992 EF-hand domain pair TOT_020001063 e8bb0afa7bb9cdb9fe3edcf7bec3a448 3445 SUPERFAMILY SSF51206 385 511 2.23E-16 T 01-11-2018 IPR018490 Cyclic nucleotide-binding-like TOT_020001063 e8bb0afa7bb9cdb9fe3edcf7bec3a448 3445 Gene3D G3DSA:2.60.120.10 366 523 1.3E-16 T 01-11-2018 IPR014710 RmlC-like jelly roll fold TOT_020001063 e8bb0afa7bb9cdb9fe3edcf7bec3a448 3445 Gene3D G3DSA:2.60.120.10 3293 3420 4.7E-15 T 01-11-2018 IPR014710 RmlC-like jelly roll fold TOT_020000323 a00ab6cf4cb56cfb4e4586494b2da4f5 1233 Pfam PF04385 Domain of unknown function, DUF529 1127 1194 6.8E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000323 a00ab6cf4cb56cfb4e4586494b2da4f5 1233 Pfam PF04385 Domain of unknown function, DUF529 77 146 2.1E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020001024 8437cb2a4991461e8ceabfbc39b769e3 707 Gene3D G3DSA:3.30.40.10 636 707 1.8E-17 T 01-11-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type TOT_020001024 8437cb2a4991461e8ceabfbc39b769e3 707 Pfam PF00097 Zinc finger, C3HC4 type (RING finger) 654 692 7.3E-9 T 01-11-2018 IPR018957 Zinc finger, C3HC4 RING-type GO:0046872 TOT_020001024 8437cb2a4991461e8ceabfbc39b769e3 707 SMART SM00184 654 692 4.7E-5 T 01-11-2018 IPR001841 Zinc finger, RING-type TOT_020001024 8437cb2a4991461e8ceabfbc39b769e3 707 ProSitePatterns PS00518 Zinc finger RING-type signature. 669 678 - T 01-11-2018 IPR017907 Zinc finger, RING-type, conserved site TOT_020001024 8437cb2a4991461e8ceabfbc39b769e3 707 SUPERFAMILY SSF57850 642 698 5.89E-14 T 01-11-2018 TOT_010001176 0e94cf75b5af7f783a19d5ee11c4004a 1506 SUPERFAMILY SSF90123 825 1149 6.02E-22 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_010001176 0e94cf75b5af7f783a19d5ee11c4004a 1506 Pfam PF00005 ABC transporter 1247 1424 4.1E-17 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_010001176 0e94cf75b5af7f783a19d5ee11c4004a 1506 SUPERFAMILY SSF52540 1210 1493 2.57E-25 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010001176 0e94cf75b5af7f783a19d5ee11c4004a 1506 Pfam PF00005 ABC transporter 528 654 1.5E-8 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_010001176 0e94cf75b5af7f783a19d5ee11c4004a 1506 SMART SM00382 537 737 2.4 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_010001176 0e94cf75b5af7f783a19d5ee11c4004a 1506 SMART SM00382 1256 1469 0.21 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_010001176 0e94cf75b5af7f783a19d5ee11c4004a 1506 SUPERFAMILY SSF52540 521 706 5.14E-19 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010001176 0e94cf75b5af7f783a19d5ee11c4004a 1506 Gene3D G3DSA:3.40.50.300 485 729 3.1E-29 T 01-11-2018 TOT_010001176 0e94cf75b5af7f783a19d5ee11c4004a 1506 Gene3D G3DSA:1.20.1560.10 813 1150 5.6E-10 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_010001176 0e94cf75b5af7f783a19d5ee11c4004a 1506 Gene3D G3DSA:3.40.50.300 1217 1505 1.1E-41 T 01-11-2018 TOT_010001176 0e94cf75b5af7f783a19d5ee11c4004a 1506 ProSitePatterns PS00211 ABC transporters family signature. 640 654 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_030000808 1db25850d3d23c2724a14e815e591232 399 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 229 391 7.9E-31 T 01-11-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TOT_030000808 1db25850d3d23c2724a14e815e591232 399 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 261 268 - T 01-11-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TOT_030000808 1db25850d3d23c2724a14e815e591232 399 SUPERFAMILY SSF53448 92 391 1.55E-37 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases TOT_020000412 8de58ccbb8e72dd4edfb5d4ccade53b7 512 Pfam PF04417 Protein of unknown function (DUF501) 334 376 2.0E-9 T 01-11-2018 IPR007511 Protein of unknown function DUF501 TOT_050000011 afb76c9c68d815d1d6468a88c145b2d7 122 PIRSF PIRSF002133 1 121 2.6E-39 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOT_050000011 afb76c9c68d815d1d6468a88c145b2d7 122 ProSitePatterns PS00055 Ribosomal protein S12 signature. 40 47 - T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOT_050000011 afb76c9c68d815d1d6468a88c145b2d7 122 Pfam PF00164 Ribosomal protein S12/S23 9 117 3.3E-25 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOT_050000011 afb76c9c68d815d1d6468a88c145b2d7 122 PRINTS PR01034 Ribosomal protein S12 signature 24 39 7.1E-27 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOT_050000011 afb76c9c68d815d1d6468a88c145b2d7 122 PRINTS PR01034 Ribosomal protein S12 signature 91 107 7.1E-27 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOT_050000011 afb76c9c68d815d1d6468a88c145b2d7 122 PRINTS PR01034 Ribosomal protein S12 signature 74 91 7.1E-27 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOT_050000011 afb76c9c68d815d1d6468a88c145b2d7 122 PRINTS PR01034 Ribosomal protein S12 signature 107 119 7.1E-27 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOT_050000011 afb76c9c68d815d1d6468a88c145b2d7 122 PRINTS PR01034 Ribosomal protein S12 signature 55 74 7.1E-27 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOT_050000011 afb76c9c68d815d1d6468a88c145b2d7 122 PRINTS PR01034 Ribosomal protein S12 signature 39 54 7.1E-27 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOT_050000011 afb76c9c68d815d1d6468a88c145b2d7 122 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 120 3.4E-35 T 01-11-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TOT_050000011 afb76c9c68d815d1d6468a88c145b2d7 122 SUPERFAMILY SSF50249 4 120 1.29E-36 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold TOT_050000011 afb76c9c68d815d1d6468a88c145b2d7 122 Gene3D G3DSA:2.40.50.140 1 122 2.2E-40 T 01-11-2018 TOT_010000187 2ded632f077b223c6418f87d0f8c2740 199 ProSitePatterns PS01104 Ribosomal protein L13e signature. 63 77 - T 01-11-2018 IPR018256 Ribosomal protein L13e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_010000187 2ded632f077b223c6418f87d0f8c2740 199 Hamap MF_00499 50S ribosomal protein L13e [rpl13e]. 38 121 20.267 T 01-11-2018 IPR001380 Ribosomal protein L13e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_010000187 2ded632f077b223c6418f87d0f8c2740 199 Pfam PF01294 Ribosomal protein L13e 2 186 5.7E-62 T 01-11-2018 IPR001380 Ribosomal protein L13e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_010001371 8333889008bf8b474ec5f0d1a91a0fda 227 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 5 212 30.92 T 01-11-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 TOT_010001371 8333889008bf8b474ec5f0d1a91a0fda 227 Pfam PF02666 Phosphatidylserine decarboxylase 41 208 1.1E-27 T 01-11-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 TOT_010001371 8333889008bf8b474ec5f0d1a91a0fda 227 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 20 211 1.6E-45 T 01-11-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 TOT_030000911 7590953113915b3951dd4e53ae9ceaa0 1018 PRINTS PR01365 Telomere reverse transcriptase signature 700 716 4.1E-7 T 01-11-2018 IPR003545 Telomerase reverse transcriptase GO:0003677|GO:0003721 Reactome: R-HSA-171319|Reactome: R-HSA-201722 TOT_030000911 7590953113915b3951dd4e53ae9ceaa0 1018 PRINTS PR01365 Telomere reverse transcriptase signature 748 760 4.1E-7 T 01-11-2018 IPR003545 Telomerase reverse transcriptase GO:0003677|GO:0003721 Reactome: R-HSA-171319|Reactome: R-HSA-201722 TOT_030000911 7590953113915b3951dd4e53ae9ceaa0 1018 PRINTS PR01365 Telomere reverse transcriptase signature 420 434 4.1E-7 T 01-11-2018 IPR003545 Telomerase reverse transcriptase GO:0003677|GO:0003721 Reactome: R-HSA-171319|Reactome: R-HSA-201722 TOT_030000911 7590953113915b3951dd4e53ae9ceaa0 1018 Gene3D G3DSA:1.10.132.70 254 453 1.5E-22 T 01-11-2018 TOT_030000911 7590953113915b3951dd4e53ae9ceaa0 1018 SMART SM00975 322 453 3.1E-16 T 01-11-2018 IPR021891 Telomerase ribonucleoprotein complex - RNA-binding domain GO:0003964 Reactome: R-HSA-171319|Reactome: R-HSA-201722 TOT_030000911 7590953113915b3951dd4e53ae9ceaa0 1018 SUPERFAMILY SSF56672 682 787 4.6E-5 T 01-11-2018 TOT_030000911 7590953113915b3951dd4e53ae9ceaa0 1018 Pfam PF12009 Telomerase ribonucleoprotein complex - RNA binding domain 323 447 5.8E-25 T 01-11-2018 IPR021891 Telomerase ribonucleoprotein complex - RNA-binding domain GO:0003964 Reactome: R-HSA-171319|Reactome: R-HSA-201722 TOT_030000911 7590953113915b3951dd4e53ae9ceaa0 1018 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 688 775 2.4E-7 T 01-11-2018 IPR000477 Reverse transcriptase domain TOT_010000420 ca7df509028b740a95041f653182d00b 927 SMART SM00744 307 360 2.4E-5 T 01-11-2018 IPR011016 Zinc finger, RING-CH-type GO:0008270 MetaCyc: PWY-7511 TOT_010000420 ca7df509028b740a95041f653182d00b 927 Pfam PF00498 FHA domain 412 461 5.6E-12 T 01-11-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TOT_010000420 ca7df509028b740a95041f653182d00b 927 Gene3D G3DSA:2.60.200.20 387 484 5.6E-16 T 01-11-2018 TOT_010000420 ca7df509028b740a95041f653182d00b 927 SUPERFAMILY SSF49879 384 459 6.7E-16 T 01-11-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 TOT_010000420 ca7df509028b740a95041f653182d00b 927 SUPERFAMILY SSF57850 308 364 6.18E-10 T 01-11-2018 TOT_010000420 ca7df509028b740a95041f653182d00b 927 SMART SM00240 410 460 2.8E-9 T 01-11-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TOT_010000420 ca7df509028b740a95041f653182d00b 927 Pfam PF12906 RING-variant domain 308 359 1.4E-8 T 01-11-2018 IPR011016 Zinc finger, RING-CH-type GO:0008270 MetaCyc: PWY-7511 TOT_010000420 ca7df509028b740a95041f653182d00b 927 Gene3D G3DSA:3.30.40.10 302 366 1.7E-11 T 01-11-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type TOT_010001080 adfc0d05bbdb04a19a9623484c263332 351 SUPERFAMILY SSF103481 246 341 3.4E-7 T 01-11-2018 TOT_010001080 adfc0d05bbdb04a19a9623484c263332 351 Pfam PF08449 UAA transporter family 17 338 9.1E-37 T 01-11-2018 IPR013657 UAA transporter GO:0055085 TOT_010000624 730ccbe10d9693bd1e7d071a7f3bef41 155 ProSitePatterns PS00299 Ubiquitin domain signature. 27 52 - T 01-11-2018 IPR019954 Ubiquitin conserved site TOT_010000624 730ccbe10d9693bd1e7d071a7f3bef41 155 PRINTS PR00348 Ubiquitin signature 11 31 5.4E-39 T 01-11-2018 IPR019956 Ubiquitin TOT_010000624 730ccbe10d9693bd1e7d071a7f3bef41 155 PRINTS PR00348 Ubiquitin signature 53 74 5.4E-39 T 01-11-2018 IPR019956 Ubiquitin TOT_010000624 730ccbe10d9693bd1e7d071a7f3bef41 155 PRINTS PR00348 Ubiquitin signature 32 52 5.4E-39 T 01-11-2018 IPR019956 Ubiquitin TOT_010000624 730ccbe10d9693bd1e7d071a7f3bef41 155 Pfam PF00240 Ubiquitin family 3 74 1.4E-34 T 01-11-2018 IPR000626 Ubiquitin domain GO:0005515 TOT_010000624 730ccbe10d9693bd1e7d071a7f3bef41 155 Pfam PF00240 Ubiquitin family 79 150 1.4E-34 T 01-11-2018 IPR000626 Ubiquitin domain GO:0005515 TOT_010000624 730ccbe10d9693bd1e7d071a7f3bef41 155 SMART SM00213 1 72 2.9E-36 T 01-11-2018 IPR000626 Ubiquitin domain GO:0005515 TOT_010000624 730ccbe10d9693bd1e7d071a7f3bef41 155 SMART SM00213 77 148 2.9E-36 T 01-11-2018 IPR000626 Ubiquitin domain GO:0005515 TOT_010000624 730ccbe10d9693bd1e7d071a7f3bef41 155 SUPERFAMILY SSF54236 76 152 1.43E-35 T 01-11-2018 IPR029071 Ubiquitin-like domain superfamily TOT_010000624 730ccbe10d9693bd1e7d071a7f3bef41 155 Gene3D G3DSA:3.10.20.90 78 155 2.4E-46 T 01-11-2018 TOT_010000624 730ccbe10d9693bd1e7d071a7f3bef41 155 Gene3D G3DSA:3.10.20.90 1 77 2.1E-46 T 01-11-2018 TOT_010000624 730ccbe10d9693bd1e7d071a7f3bef41 155 ProSitePatterns PS00299 Ubiquitin domain signature. 103 128 - T 01-11-2018 IPR019954 Ubiquitin conserved site TOT_010000624 730ccbe10d9693bd1e7d071a7f3bef41 155 SUPERFAMILY SSF54236 1 76 4.77E-35 T 01-11-2018 IPR029071 Ubiquitin-like domain superfamily TOT_030000155 ce6eb995ab386261a568ed67003a981f 168 ProSitePatterns PS00628 Ribosomal protein S19e signature. 110 129 - T 01-11-2018 IPR018277 Ribosomal protein S19e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_030000155 ce6eb995ab386261a568ed67003a981f 168 Gene3D G3DSA:1.10.10.2700 2 168 4.4E-61 T 01-11-2018 IPR038111 Ribosomal protein S19e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_030000155 ce6eb995ab386261a568ed67003a981f 168 SMART SM01413 26 163 2.2E-68 T 01-11-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_030000155 ce6eb995ab386261a568ed67003a981f 168 SUPERFAMILY SSF46785 26 165 3.4E-48 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily TOT_030000155 ce6eb995ab386261a568ed67003a981f 168 ProDom PD003854 RIBOSOMAL 40S RIBONUCLEOPROTEIN S19 S19E 30S MULTIGENE FAMILY S19 SSU 26 137 1.0E-59 T 01-11-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_030000155 ce6eb995ab386261a568ed67003a981f 168 Pfam PF01090 Ribosomal protein S19e 27 162 9.9E-50 T 01-11-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_020000332 8ebfe4247645bab79b6766414d37e0c1 986 SUPERFAMILY SSF54001 75 480 3.27E-60 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily TOT_020000332 8ebfe4247645bab79b6766414d37e0c1 986 Pfam PF00443 Ubiquitin carboxyl-terminal hydrolase 79 479 5.4E-33 T 01-11-2018 IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase GO:0016579|GO:0036459 TOT_020000332 8ebfe4247645bab79b6766414d37e0c1 986 Gene3D G3DSA:3.90.70.10 380 483 1.1E-21 T 01-11-2018 TOT_020000332 8ebfe4247645bab79b6766414d37e0c1 986 Gene3D G3DSA:3.90.70.10 71 365 3.0E-44 T 01-11-2018 TOT_040000054 0c416d85f6b17d173f3dda30fef6b9af 905 Gene3D G3DSA:3.40.50.10810 279 590 1.1E-41 T 01-11-2018 IPR038718 SNF2-like, N-terminal domain superfamily TOT_040000054 0c416d85f6b17d173f3dda30fef6b9af 905 Pfam PF00271 Helicase conserved C-terminal domain 701 853 1.1E-7 T 01-11-2018 IPR001650 Helicase, C-terminal TOT_040000054 0c416d85f6b17d173f3dda30fef6b9af 905 Pfam PF00176 SNF2 family N-terminal domain 332 589 7.5E-25 T 01-11-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 TOT_040000054 0c416d85f6b17d173f3dda30fef6b9af 905 SMART SM00487 309 531 3.4E-23 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOT_040000054 0c416d85f6b17d173f3dda30fef6b9af 905 SMART SM00490 723 853 3.3E-9 T 01-11-2018 IPR001650 Helicase, C-terminal TOT_040000054 0c416d85f6b17d173f3dda30fef6b9af 905 SUPERFAMILY SSF52540 283 567 6.52E-33 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_040000054 0c416d85f6b17d173f3dda30fef6b9af 905 SUPERFAMILY SSF52540 462 896 8.45E-40 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010001364 61888d9e6d6b271f00614f3b928b2327 541 Pfam PF02847 MA3 domain 349 455 9.2E-21 T 01-11-2018 IPR003891 Initiation factor eIF-4 gamma, MA3 TOT_010001364 61888d9e6d6b271f00614f3b928b2327 541 SUPERFAMILY SSF48371 46 283 4.48E-58 T 01-11-2018 IPR016024 Armadillo-type fold TOT_010001364 61888d9e6d6b271f00614f3b928b2327 541 Pfam PF02854 MIF4G domain 57 239 7.2E-13 T 01-11-2018 IPR003890 MIF4G-like, type 3 GO:0003723|GO:0005515 TOT_010001364 61888d9e6d6b271f00614f3b928b2327 541 SMART SM00544 349 455 3.3E-24 T 01-11-2018 IPR003891 Initiation factor eIF-4 gamma, MA3 TOT_010001364 61888d9e6d6b271f00614f3b928b2327 541 Gene3D G3DSA:1.25.40.180 12 302 2.7E-78 T 01-11-2018 IPR016021 MIF4G-like domain superfamily TOT_010001364 61888d9e6d6b271f00614f3b928b2327 541 SMART SM00543 56 239 2.0E-32 T 01-11-2018 IPR003890 MIF4G-like, type 3 GO:0003723|GO:0005515 TOT_010001238 3d589a5cdf698f4df3c4bf8102dbca2a 148 Pfam PF01448 ELM2 domain 17 82 1.2E-5 T 01-11-2018 IPR000949 ELM2 domain TOT_040000679 8af27239a7d4fd3eaae176fd4b61ba12 358 Gene3D G3DSA:3.30.530.20 136 340 6.8E-23 T 01-11-2018 IPR023393 START-like domain superfamily TOT_040000679 8af27239a7d4fd3eaae176fd4b61ba12 358 Pfam PF01852 START domain 155 316 1.8E-5 T 01-11-2018 IPR002913 START domain GO:0008289 TOT_040000679 8af27239a7d4fd3eaae176fd4b61ba12 358 SUPERFAMILY SSF55961 160 332 6.46E-20 T 01-11-2018 TOT_020000401 fb084ff73f779ecd8817433211a818a6 375 Pfam PF04677 Protein similar to CwfJ C-terminus 1 82 172 4.4E-11 T 01-11-2018 IPR006768 Cwf19-like, C-terminal domain-1 TOT_020000401 fb084ff73f779ecd8817433211a818a6 375 Pfam PF04676 Protein similar to CwfJ C-terminus 2 281 372 3.2E-15 T 01-11-2018 IPR006767 Cwf19-like protein, C-terminal domain-2 TOT_010000006 8006132decdb19bd9e55d8b069901dc4 1504 Pfam PF00005 ABC transporter 521 647 3.9E-12 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_010000006 8006132decdb19bd9e55d8b069901dc4 1504 Gene3D G3DSA:3.40.50.300 1207 1502 3.1E-42 T 01-11-2018 TOT_010000006 8006132decdb19bd9e55d8b069901dc4 1504 SUPERFAMILY SSF52540 514 699 4.18E-22 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010000006 8006132decdb19bd9e55d8b069901dc4 1504 SMART SM00382 530 730 0.98 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_010000006 8006132decdb19bd9e55d8b069901dc4 1504 SMART SM00382 1249 1467 0.073 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_010000006 8006132decdb19bd9e55d8b069901dc4 1504 Pfam PF00005 ABC transporter 1240 1422 1.8E-17 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_010000006 8006132decdb19bd9e55d8b069901dc4 1504 Gene3D G3DSA:3.40.50.300 475 722 4.9E-34 T 01-11-2018 TOT_010000006 8006132decdb19bd9e55d8b069901dc4 1504 ProSitePatterns PS00211 ABC transporters family signature. 633 647 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_010000006 8006132decdb19bd9e55d8b069901dc4 1504 SUPERFAMILY SSF52540 1201 1491 6.52E-26 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010000006 8006132decdb19bd9e55d8b069901dc4 1504 Gene3D G3DSA:1.20.1560.10 804 1143 1.5E-9 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_010000006 8006132decdb19bd9e55d8b069901dc4 1504 SUPERFAMILY SSF90123 818 1142 1.31E-20 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000576 d1ced1cb261249e57bd316f43be57d27 269 Gene3D G3DSA:3.30.2350.10 5 255 1.7E-5 T 01-11-2018 TOT_010001152 3687bedbe0b0c1de64d1b2d13aeb5c32 570 SUPERFAMILY SSF52374 71 407 6.19E-73 T 01-11-2018 TOT_010001152 3687bedbe0b0c1de64d1b2d13aeb5c32 570 SUPERFAMILY SSF47323 410 548 4.36E-11 T 01-11-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TOT_010001152 3687bedbe0b0c1de64d1b2d13aeb5c32 570 Gene3D G3DSA:3.40.50.620 74 393 5.3E-94 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOT_010001152 3687bedbe0b0c1de64d1b2d13aeb5c32 570 Pfam PF09334 tRNA synthetases class I (M) 220 419 3.0E-37 T 01-11-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 TOT_010001152 3687bedbe0b0c1de64d1b2d13aeb5c32 570 Pfam PF09334 tRNA synthetases class I (M) 74 214 2.7E-30 T 01-11-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 TOT_010001152 3687bedbe0b0c1de64d1b2d13aeb5c32 570 PRINTS PR01041 Methionyl-tRNA synthetase signature 407 418 8.9E-23 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TOT_010001152 3687bedbe0b0c1de64d1b2d13aeb5c32 570 PRINTS PR01041 Methionyl-tRNA synthetase signature 318 333 8.9E-23 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TOT_010001152 3687bedbe0b0c1de64d1b2d13aeb5c32 570 PRINTS PR01041 Methionyl-tRNA synthetase signature 108 122 8.9E-23 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TOT_010001152 3687bedbe0b0c1de64d1b2d13aeb5c32 570 PRINTS PR01041 Methionyl-tRNA synthetase signature 76 89 8.9E-23 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TOT_010001152 3687bedbe0b0c1de64d1b2d13aeb5c32 570 PRINTS PR01041 Methionyl-tRNA synthetase signature 288 299 8.9E-23 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TOT_010001152 3687bedbe0b0c1de64d1b2d13aeb5c32 570 Gene3D G3DSA:1.10.730.10 400 551 2.7E-12 T 01-11-2018 TOT_010001152 3687bedbe0b0c1de64d1b2d13aeb5c32 570 Gene3D G3DSA:2.170.220.10 185 290 5.3E-94 T 01-11-2018 TOT_030000660 c0414345fe993cbc7736899324fe74ba 238 TIGRFAM TIGR00061 L21: ribosomal protein bL21 62 162 2.2E-13 T 01-11-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TOT_030000660 c0414345fe993cbc7736899324fe74ba 238 Pfam PF00829 Ribosomal prokaryotic L21 protein 62 160 6.4E-22 T 01-11-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TOT_030000660 c0414345fe993cbc7736899324fe74ba 238 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 61 164 16.41 T 01-11-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TOT_030000660 c0414345fe993cbc7736899324fe74ba 238 SUPERFAMILY SSF141091 62 162 1.11E-24 T 01-11-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TOT_010000614 bafb83679abb09e864eb6f838c42bad5 391 Gene3D G3DSA:3.20.20.190 2 203 1.8E-24 T 01-11-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TOT_010000614 bafb83679abb09e864eb6f838c42bad5 391 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 9 189 3.1E-14 T 01-11-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 TOT_010000614 bafb83679abb09e864eb6f838c42bad5 391 SUPERFAMILY SSF51695 5 382 1.47E-25 T 01-11-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TOT_040000166 e471d0cc4e71b0f8dfccf9ccf18f9b29 588 SUPERFAMILY SSF46785 482 559 8.98E-16 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily TOT_040000166 e471d0cc4e71b0f8dfccf9ccf18f9b29 588 Gene3D G3DSA:1.25.40.570 396 587 3.3E-54 T 01-11-2018 TOT_040000166 e471d0cc4e71b0f8dfccf9ccf18f9b29 588 SMART SM00088 487 570 1.5E-15 T 01-11-2018 IPR000717 Proteasome component (PCI) domain TOT_040000166 e471d0cc4e71b0f8dfccf9ccf18f9b29 588 Gene3D G3DSA:1.25.40.570 73 289 5.2E-47 T 01-11-2018 TOT_040000166 e471d0cc4e71b0f8dfccf9ccf18f9b29 588 SMART SM00753 motif in proteasome subunits, Int-6, Nip-1 and TRIP-15 487 570 1.5E-15 T 01-11-2018 TOT_040000166 e471d0cc4e71b0f8dfccf9ccf18f9b29 588 Pfam PF01399 PCI domain 458 553 5.2E-18 T 01-11-2018 IPR000717 Proteasome component (PCI) domain TOT_020000712 5c79bf955107ceaa5d7a1cf894c62604 598 Gene3D G3DSA:1.20.1250.20 370 581 2.0E-6 T 01-11-2018 TOT_020000712 5c79bf955107ceaa5d7a1cf894c62604 598 Gene3D G3DSA:1.20.1250.20 59 248 3.0E-10 T 01-11-2018 TOT_020000712 5c79bf955107ceaa5d7a1cf894c62604 598 SUPERFAMILY SSF103473 65 584 3.92E-23 T 01-11-2018 IPR036259 MFS transporter superfamily TOT_020000712 5c79bf955107ceaa5d7a1cf894c62604 598 Pfam PF07690 Major Facilitator Superfamily 75 545 2.4E-8 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOT_030000928 619a68e333c5767bd98aa9870944c4b4 290 Gene3D G3DSA:2.30.30.30 114 172 7.6E-7 T 01-11-2018 IPR014722 Ribosomal protein L2, domain 2 TOT_030000928 619a68e333c5767bd98aa9870944c4b4 290 SUPERFAMILY SSF50249 248 286 1.64E-5 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold TOT_030000928 619a68e333c5767bd98aa9870944c4b4 290 Gene3D G3DSA:2.40.50.140 243 288 4.0E-8 T 01-11-2018 TOT_030000928 619a68e333c5767bd98aa9870944c4b4 290 SUPERFAMILY SSF50104 114 172 2.35E-6 T 01-11-2018 IPR008991 Translation protein SH3-like domain superfamily TOT_030000928 619a68e333c5767bd98aa9870944c4b4 290 SMART SM00841 240 286 9.5E-6 T 01-11-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 TOT_030000928 619a68e333c5767bd98aa9870944c4b4 290 Pfam PF09285 Elongation factor P, C-terminal 252 286 6.9E-8 T 01-11-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 TOT_030000528 caeb6fc3a90bcdcf71ca96a0feb92676 200 Gene3D G3DSA:2.60.40.790 61 185 2.8E-15 T 01-11-2018 IPR008978 HSP20-like chaperone TOT_030000528 caeb6fc3a90bcdcf71ca96a0feb92676 200 Pfam PF04969 CS domain 76 164 3.2E-8 T 01-11-2018 IPR007052 CS domain TOT_030000528 caeb6fc3a90bcdcf71ca96a0feb92676 200 SUPERFAMILY SSF49764 72 180 3.35E-11 T 01-11-2018 IPR008978 HSP20-like chaperone TOT_030000710 d204a15087fbce11f28b7742545c9caa 640 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 191 214 - T 01-11-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TOT_030000710 d204a15087fbce11f28b7742545c9caa 640 SUPERFAMILY SSF56112 175 590 2.33E-77 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily TOT_030000710 d204a15087fbce11f28b7742545c9caa 640 SMART SM00220 185 580 5.6E-61 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOT_030000710 d204a15087fbce11f28b7742545c9caa 640 Pfam PF00069 Protein kinase domain 186 255 5.5E-11 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOT_030000710 d204a15087fbce11f28b7742545c9caa 640 Pfam PF00069 Protein kinase domain 368 580 5.6E-44 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOT_030000710 d204a15087fbce11f28b7742545c9caa 640 Gene3D G3DSA:1.10.510.10 372 622 6.3E-61 T 01-11-2018 TOT_030000710 d204a15087fbce11f28b7742545c9caa 640 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 403 415 - T 01-11-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TOT_030000710 d204a15087fbce11f28b7742545c9caa 640 Gene3D G3DSA:3.30.200.20 172 265 2.2E-21 T 01-11-2018 TOT_040000853 3d7aef2aaa1341fd41fc1cb29315443f 1047 Pfam PF04385 Domain of unknown function, DUF529 550 612 1.0E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000853 3d7aef2aaa1341fd41fc1cb29315443f 1047 Pfam PF04385 Domain of unknown function, DUF529 768 820 3.6E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000853 3d7aef2aaa1341fd41fc1cb29315443f 1047 Pfam PF04385 Domain of unknown function, DUF529 393 461 2.3E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000708 d9c686fc2db10a524f3cad53eacb030c 667 SUPERFAMILY SSF82708 246 303 1.83E-6 T 01-11-2018 IPR036867 R3H domain superfamily GO:0003676 TOT_020000708 d9c686fc2db10a524f3cad53eacb030c 667 Gene3D G3DSA:3.30.70.330 574 666 1.6E-15 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_020000708 d9c686fc2db10a524f3cad53eacb030c 667 Pfam PF08675 RNA binding domain 586 656 2.7E-7 T 01-11-2018 IPR014789 Poly(A)-specific ribonuclease, RNA-binding GO:0003723|GO:0004535|GO:0005634|GO:0005737|GO:0006402|GO:0046872 Reactome: R-HSA-380994|Reactome: R-HSA-429947|Reactome: R-HSA-450604 TOT_020000708 d9c686fc2db10a524f3cad53eacb030c 667 Gene3D G3DSA:3.30.1370.50 238 312 4.3E-71 T 01-11-2018 IPR036867 R3H domain superfamily GO:0003676 TOT_020000708 d9c686fc2db10a524f3cad53eacb030c 667 Pfam PF04857 CAF1 family ribonuclease 85 477 8.4E-76 T 01-11-2018 IPR006941 Ribonuclease CAF1 TOT_020000708 d9c686fc2db10a524f3cad53eacb030c 667 SUPERFAMILY SSF53098 86 488 9.76E-53 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily TOT_020000708 d9c686fc2db10a524f3cad53eacb030c 667 Gene3D G3DSA:3.30.420.10 84 479 4.3E-71 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TOT_010000355 e1f69dabf90dfd2b473013f64fb0d684 1152 Pfam PF00773 RNB domain 374 908 8.6E-98 T 01-11-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 TOT_010000355 e1f69dabf90dfd2b473013f64fb0d684 1152 SUPERFAMILY SSF50249 127 328 4.97E-7 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold TOT_010000355 e1f69dabf90dfd2b473013f64fb0d684 1152 Gene3D G3DSA:2.40.50.700 257 332 2.8E-5 T 01-11-2018 TOT_010000355 e1f69dabf90dfd2b473013f64fb0d684 1152 SMART SM00955 374 908 1.0E-81 T 01-11-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 TOT_010000355 e1f69dabf90dfd2b473013f64fb0d684 1152 SUPERFAMILY SSF50249 303 949 1.13E-86 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold TOT_010000062 ea5fd7025da70a6c5a1a4e3daaa1514f 93 SUPERFAMILY SSF47027 3 87 2.75E-29 T 01-11-2018 IPR035984 Acyl-CoA binding protein superfamily GO:0000062 TOT_010000062 ea5fd7025da70a6c5a1a4e3daaa1514f 93 Pfam PF00887 Acyl CoA binding protein 3 82 1.3E-29 T 01-11-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 TOT_010000062 ea5fd7025da70a6c5a1a4e3daaa1514f 93 PRINTS PR00689 Acyl-coA-binding protein signature 44 59 1.4E-19 T 01-11-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 TOT_010000062 ea5fd7025da70a6c5a1a4e3daaa1514f 93 PRINTS PR00689 Acyl-coA-binding protein signature 3 18 1.4E-19 T 01-11-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 TOT_010000062 ea5fd7025da70a6c5a1a4e3daaa1514f 93 PRINTS PR00689 Acyl-coA-binding protein signature 21 39 1.4E-19 T 01-11-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 TOT_010000062 ea5fd7025da70a6c5a1a4e3daaa1514f 93 PRINTS PR00689 Acyl-coA-binding protein signature 65 82 1.4E-19 T 01-11-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 TOT_010000062 ea5fd7025da70a6c5a1a4e3daaa1514f 93 Gene3D G3DSA:1.20.80.10 1 88 3.5E-35 T 01-11-2018 IPR014352 FERM/acyl-CoA-binding protein superfamily TOT_010000517 07cb14143a886c56827ca5b75933bbb3 738 Gene3D G3DSA:1.25.40.90 19 163 2.1E-22 T 01-11-2018 IPR008942 ENTH/VHS TOT_010000517 07cb14143a886c56827ca5b75933bbb3 738 SUPERFAMILY SSF48464 21 163 2.4E-25 T 01-11-2018 IPR008942 ENTH/VHS TOT_010000517 07cb14143a886c56827ca5b75933bbb3 738 Pfam PF01417 ENTH domain 24 145 5.4E-19 T 01-11-2018 IPR013809 ENTH domain TOT_010000517 07cb14143a886c56827ca5b75933bbb3 738 SMART SM00273 24 149 0.0022 T 01-11-2018 IPR013809 ENTH domain TOT_020000410 99f8ba522fadda3530ab17016f48fcbc 715 SUPERFAMILY SSF47954 249 409 4.35E-6 T 01-11-2018 IPR036915 Cyclin-like superfamily TOT_020000410 99f8ba522fadda3530ab17016f48fcbc 715 Gene3D G3DSA:1.10.472.10 272 410 7.9E-7 T 01-11-2018 TOT_020000914 0b5ced291535baac21d3a752d697673c 212 Pfam PF04385 Domain of unknown function, DUF529 118 172 2.4E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_030000433 8a0d18ed06f3be73e41861b2aa4ad817 276 Gene3D G3DSA:2.60.120.620 57 269 2.5E-42 T 01-11-2018 TOT_030000433 8a0d18ed06f3be73e41861b2aa4ad817 276 SMART SM00702 74 269 1.8E-18 T 01-11-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 TOT_030000433 8a0d18ed06f3be73e41861b2aa4ad817 276 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 172 268 4.3E-9 T 01-11-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 TOT_030000927 61b3b96e1155014c0bdcb897a2bd2dc5 207 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 141 207 1.0E-6 T 01-11-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TOT_030000927 61b3b96e1155014c0bdcb897a2bd2dc5 207 Gene3D G3DSA:3.30.1390.10 133 207 2.4E-6 T 01-11-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TOT_030000927 61b3b96e1155014c0bdcb897a2bd2dc5 207 SUPERFAMILY SSF54736 139 207 4.88E-9 T 01-11-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TOT_030000927 61b3b96e1155014c0bdcb897a2bd2dc5 207 SUPERFAMILY SSF48300 67 105 4.32E-10 T 01-11-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TOT_030000927 61b3b96e1155014c0bdcb897a2bd2dc5 207 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 68 104 3.7E-13 T 01-11-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TOT_030000927 61b3b96e1155014c0bdcb897a2bd2dc5 207 Gene3D G3DSA:1.20.5.710 68 127 2.4E-10 T 01-11-2018 TOT_020000557 31aad9db7bd375dec129a493ed7b0071 223 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 67 81 - T 01-11-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 TOT_020000557 31aad9db7bd375dec129a493ed7b0071 223 SUPERFAMILY SSF51419 5 222 1.29E-56 T 01-11-2018 IPR029066 PLP-binding barrel TOT_020000557 31aad9db7bd375dec129a493ed7b0071 223 PIRSF PIRSF004848 3 223 2.0E-54 T 01-11-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 TOT_020000557 31aad9db7bd375dec129a493ed7b0071 223 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 19 222 1.4E-43 T 01-11-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 TOT_020000557 31aad9db7bd375dec129a493ed7b0071 223 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 6 223 23.337 T 01-11-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 TOT_020000557 31aad9db7bd375dec129a493ed7b0071 223 Gene3D G3DSA:3.20.20.10 5 223 4.3E-62 T 01-11-2018 IPR029066 PLP-binding barrel TOT_020000557 31aad9db7bd375dec129a493ed7b0071 223 Pfam PF01168 Alanine racemase, N-terminal domain 8 222 4.4E-8 T 01-11-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TOT_010000092 5e94d9b5a39573976849d3bd32cfc633 716 Pfam PF17286 PRMT5 oligomerisation domain 529 712 7.6E-45 T 01-11-2018 IPR035248 PRMT5, oligomerisation domain Reactome: R-HSA-191859|Reactome: R-HSA-3214858|Reactome: R-HSA-6804760 TOT_010000092 5e94d9b5a39573976849d3bd32cfc633 716 SUPERFAMILY SSF53335 407 713 3.32E-17 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOT_010000092 5e94d9b5a39573976849d3bd32cfc633 716 Gene3D G3DSA:3.40.50.150 305 528 7.8E-51 T 01-11-2018 TOT_010000092 5e94d9b5a39573976849d3bd32cfc633 716 Pfam PF17285 PRMT5 TIM barrel domain 38 309 2.5E-35 T 01-11-2018 IPR035247 PRMT5, TIM barrel domain Reactome: R-HSA-191859|Reactome: R-HSA-3214858|Reactome: R-HSA-6804760 TOT_010000092 5e94d9b5a39573976849d3bd32cfc633 716 PIRSF PIRSF015894 88 715 2.1E-95 T 01-11-2018 IPR007857 Protein arginine N-methyltransferase PRMT5 GO:0006479|GO:0008168|GO:0035246 Reactome: R-HSA-191859|Reactome: R-HSA-3214858|Reactome: R-HSA-6804760 TOT_010000092 5e94d9b5a39573976849d3bd32cfc633 716 Gene3D G3DSA:2.70.160.11 529 715 5.7E-48 T 01-11-2018 TOT_010000092 5e94d9b5a39573976849d3bd32cfc633 716 Gene3D G3DSA:3.20.20.150 24 274 5.2E-13 T 01-11-2018 TOT_010000092 5e94d9b5a39573976849d3bd32cfc633 716 Pfam PF05185 PRMT5 arginine-N-methyltransferase 317 517 8.2E-52 T 01-11-2018 IPR035075 PRMT5 arginine-N-methyltransferase Reactome: R-HSA-191859|Reactome: R-HSA-3214858|Reactome: R-HSA-6804760 TOT_030000450 656f970911c6c27f6c5b8500a64d9890 1768 Pfam PF12854 PPR repeat 1415 1446 3.7E-8 T 01-11-2018 IPR002885 Pentatricopeptide repeat TOT_030000450 656f970911c6c27f6c5b8500a64d9890 1768 Pfam PF13041 PPR repeat family 1452 1500 6.7E-15 T 01-11-2018 IPR002885 Pentatricopeptide repeat TOT_030000450 656f970911c6c27f6c5b8500a64d9890 1768 Pfam PF13041 PPR repeat family 1594 1641 1.0E-12 T 01-11-2018 IPR002885 Pentatricopeptide repeat TOT_030000450 656f970911c6c27f6c5b8500a64d9890 1768 Pfam PF13041 PPR repeat family 1522 1569 1.3E-9 T 01-11-2018 IPR002885 Pentatricopeptide repeat TOT_030000450 656f970911c6c27f6c5b8500a64d9890 1768 TIGRFAM TIGR00756 PPR: pentatricopeptide repeat domain 1420 1454 1.5E-8 T 01-11-2018 IPR002885 Pentatricopeptide repeat TOT_030000450 656f970911c6c27f6c5b8500a64d9890 1768 TIGRFAM TIGR00756 PPR: pentatricopeptide repeat domain 1597 1630 1.8E-6 T 01-11-2018 IPR002885 Pentatricopeptide repeat TOT_030000450 656f970911c6c27f6c5b8500a64d9890 1768 TIGRFAM TIGR00756 PPR: pentatricopeptide repeat domain 1526 1558 2.4E-4 T 01-11-2018 IPR002885 Pentatricopeptide repeat TOT_030000450 656f970911c6c27f6c5b8500a64d9890 1768 TIGRFAM TIGR00756 PPR: pentatricopeptide repeat domain 1455 1488 1.1E-7 T 01-11-2018 IPR002885 Pentatricopeptide repeat TOT_030000450 656f970911c6c27f6c5b8500a64d9890 1768 TIGRFAM TIGR00756 PPR: pentatricopeptide repeat domain 1385 1418 1.0E-5 T 01-11-2018 IPR002885 Pentatricopeptide repeat TOT_030000450 656f970911c6c27f6c5b8500a64d9890 1768 TIGRFAM TIGR00756 PPR: pentatricopeptide repeat domain 1490 1524 2.1E-5 T 01-11-2018 IPR002885 Pentatricopeptide repeat TOT_030000450 656f970911c6c27f6c5b8500a64d9890 1768 Gene3D G3DSA:1.25.40.10 1510 1728 1.9E-36 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TOT_030000450 656f970911c6c27f6c5b8500a64d9890 1768 Pfam PF13812 Pentatricopeptide repeat domain 1222 1273 0.0045 T 01-11-2018 IPR002885 Pentatricopeptide repeat TOT_030000450 656f970911c6c27f6c5b8500a64d9890 1768 Gene3D G3DSA:1.25.40.10 1179 1323 7.1E-6 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TOT_030000450 656f970911c6c27f6c5b8500a64d9890 1768 Gene3D G3DSA:1.25.40.10 1353 1509 1.3E-39 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TOT_030000450 656f970911c6c27f6c5b8500a64d9890 1768 Pfam PF01535 PPR repeat 1385 1413 8.2E-5 T 01-11-2018 IPR002885 Pentatricopeptide repeat TOT_030000381 f4dd2ea5e870c0d47ff0a04caf5c06c3 93 Gene3D G3DSA:1.10.30.10 17 93 1.8E-30 T 01-11-2018 IPR036910 High mobility group box domain superfamily TOT_030000381 f4dd2ea5e870c0d47ff0a04caf5c06c3 93 SUPERFAMILY SSF47095 7 91 1.19E-25 T 01-11-2018 IPR036910 High mobility group box domain superfamily TOT_030000381 f4dd2ea5e870c0d47ff0a04caf5c06c3 93 SMART SM00398 21 93 1.1E-24 T 01-11-2018 IPR009071 High mobility group box domain TOT_030000381 f4dd2ea5e870c0d47ff0a04caf5c06c3 93 Pfam PF00505 HMG (high mobility group) box 22 91 1.8E-22 T 01-11-2018 IPR009071 High mobility group box domain TOT_020000782 e150dd7706d5bfbed6efd4cae88e55fe 1515 Gene3D G3DSA:3.40.50.300 488 773 1.1E-34 T 01-11-2018 TOT_020000782 e150dd7706d5bfbed6efd4cae88e55fe 1515 Pfam PF00005 ABC transporter 1253 1433 4.5E-17 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000782 e150dd7706d5bfbed6efd4cae88e55fe 1515 Pfam PF00005 ABC transporter 534 661 4.4E-13 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000782 e150dd7706d5bfbed6efd4cae88e55fe 1515 SUPERFAMILY SSF52540 527 729 1.08E-23 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000782 e150dd7706d5bfbed6efd4cae88e55fe 1515 Gene3D G3DSA:3.40.50.300 1221 1510 1.9E-42 T 01-11-2018 TOT_020000782 e150dd7706d5bfbed6efd4cae88e55fe 1515 SUPERFAMILY SSF90123 124 236 4.97E-5 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000782 e150dd7706d5bfbed6efd4cae88e55fe 1515 SMART SM00382 543 746 0.46 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000782 e150dd7706d5bfbed6efd4cae88e55fe 1515 SMART SM00382 1262 1502 0.56 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000782 e150dd7706d5bfbed6efd4cae88e55fe 1515 SUPERFAMILY SSF52540 1213 1502 1.63E-26 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000782 e150dd7706d5bfbed6efd4cae88e55fe 1515 ProSitePatterns PS00211 ABC transporters family signature. 646 660 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_020000782 e150dd7706d5bfbed6efd4cae88e55fe 1515 SUPERFAMILY SSF90123 835 1153 3.14E-17 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_030000173 989bee9a20bc30834c3a245486343334 262 ProSitePatterns PS01191 Ribosomal protein S3Ae signature. 61 73 - T 01-11-2018 IPR018281 Ribosomal protein S3Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_030000173 989bee9a20bc30834c3a245486343334 262 Pfam PF01015 Ribosomal S3Ae family 15 221 1.6E-89 T 01-11-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_030000173 989bee9a20bc30834c3a245486343334 262 Hamap MF_03122 40S ribosomal protein S1 [RPS3A]. 1 254 38.69 T 01-11-2018 IPR027500 40S ribosomal protein S1/3, eukaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_030000173 989bee9a20bc30834c3a245486343334 262 SMART SM01397 15 221 2.5E-125 T 01-11-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_040000468 13301f00392eae46167a899a72244362 252 Pfam PF00642 Zinc finger C-x8-C-x5-C-x3-H type (and similar) 75 96 3.3E-6 T 01-11-2018 IPR000571 Zinc finger, CCCH-type GO:0046872 TOT_040000468 13301f00392eae46167a899a72244362 252 Gene3D G3DSA:4.10.1000.10 48 102 1.5E-5 T 01-11-2018 TOT_040000468 13301f00392eae46167a899a72244362 252 Gene3D G3DSA:4.10.1000.10 103 177 1.5E-8 T 01-11-2018 TOT_040000468 13301f00392eae46167a899a72244362 252 SMART SM00356 103 130 2.2 T 01-11-2018 IPR000571 Zinc finger, CCCH-type GO:0046872 TOT_040000468 13301f00392eae46167a899a72244362 252 SMART SM00356 132 156 1.7 T 01-11-2018 IPR000571 Zinc finger, CCCH-type GO:0046872 TOT_040000468 13301f00392eae46167a899a72244362 252 SMART SM00356 70 97 0.014 T 01-11-2018 IPR000571 Zinc finger, CCCH-type GO:0046872 TOT_040000468 13301f00392eae46167a899a72244362 252 SUPERFAMILY SSF90229 75 100 4.32E-6 T 01-11-2018 IPR036855 Zinc finger, CCCH-type superfamily GO:0046872 TOT_030000356 f936447f068018693ed220d1840c0934 950 Pfam PF08700 Vps51/Vps67 64 147 3.0E-14 T 01-11-2018 TOT_020000284 15bf03bf72bc9db9dc73893fbabf8a01 243 Pfam PF10075 CSN8/PSMD8/EIF3K family 65 196 3.5E-17 T 01-11-2018 IPR033464 CSN8/PSMD8/EIF3K TOT_020000284 15bf03bf72bc9db9dc73893fbabf8a01 243 Hamap MF_03010 Eukaryotic translation initiation factor 3 subunit K [EIF3K]. 6 237 20.028 T 01-11-2018 IPR009374 Eukaryotic translation initiation factor 3 subunit K GO:0003743|GO:0005737|GO:0005852 Reactome: R-HSA-156827|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706 TOT_020000284 15bf03bf72bc9db9dc73893fbabf8a01 243 Gene3D G3DSA:1.25.40.250 8 124 2.5E-26 T 01-11-2018 IPR016020 Translation initiation factor 3, subunit 12, N-terminal, eukaryotic GO:0003743|GO:0005852|GO:0006446|GO:0043022 Reactome: R-HSA-156827|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706 TOT_020000284 15bf03bf72bc9db9dc73893fbabf8a01 243 SUPERFAMILY SSF46785 141 212 1.6E-5 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily TOT_020000284 15bf03bf72bc9db9dc73893fbabf8a01 243 SUPERFAMILY SSF48371 22 129 5.75E-27 T 01-11-2018 IPR016024 Armadillo-type fold TOT_010001225 ba1a654e45725ee0fe37afff865ec5ba 663 Gene3D G3DSA:2.40.50.140 436 526 6.4E-8 T 01-11-2018 TOT_010001225 ba1a654e45725ee0fe37afff865ec5ba 663 Gene3D G3DSA:2.40.50.140 54 143 2.9E-8 T 01-11-2018 TOT_010001225 ba1a654e45725ee0fe37afff865ec5ba 663 Gene3D G3DSA:2.40.50.140 154 228 1.6E-6 T 01-11-2018 TOT_010001225 ba1a654e45725ee0fe37afff865ec5ba 663 SUPERFAMILY SSF50249 443 550 7.55E-11 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold TOT_010001225 ba1a654e45725ee0fe37afff865ec5ba 663 SUPERFAMILY SSF50249 58 147 1.04E-8 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold TOT_010001225 ba1a654e45725ee0fe37afff865ec5ba 663 SMART SM00316 453 524 8.4E-4 T 01-11-2018 IPR022967 RNA-binding domain, S1 TOT_010001225 ba1a654e45725ee0fe37afff865ec5ba 663 SMART SM00316 358 438 61.0 T 01-11-2018 IPR022967 RNA-binding domain, S1 TOT_010001225 ba1a654e45725ee0fe37afff865ec5ba 663 SMART SM00316 65 141 8.4E-6 T 01-11-2018 IPR022967 RNA-binding domain, S1 TOT_010001225 ba1a654e45725ee0fe37afff865ec5ba 663 SUPERFAMILY SSF50249 137 226 8.32E-5 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold TOT_010000319 55b4c15cbe6ab45b16a167789f27e998 292 Pfam PF12998 Inhibitor of growth proteins N-terminal histone-binding 4 67 1.3E-4 T 01-11-2018 IPR024610 Inhibitor of growth protein, N-terminal histone-binding TOT_010000319 55b4c15cbe6ab45b16a167789f27e998 292 SMART SM01408 3 192 1.0E-9 T 01-11-2018 IPR024610 Inhibitor of growth protein, N-terminal histone-binding TOT_040000070 57bc0fc52e6e38109f2bd101d4665e48 1568 SUPERFAMILY SSF48371 227 461 1.82E-10 T 01-11-2018 IPR016024 Armadillo-type fold TOT_040000070 57bc0fc52e6e38109f2bd101d4665e48 1568 SUPERFAMILY SSF48371 403 1562 1.61E-29 T 01-11-2018 IPR016024 Armadillo-type fold TOT_010000664 81077782b64f0da5d421201c6c28b7ce 166 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 95 143 - T 01-11-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TOT_010000664 81077782b64f0da5d421201c6c28b7ce 166 Gene3D G3DSA:2.60.40.420 35 163 9.5E-39 T 01-11-2018 IPR008972 Cupredoxin TOT_010000664 81077782b64f0da5d421201c6c28b7ce 166 SUPERFAMILY SSF49503 35 163 2.32E-40 T 01-11-2018 IPR008972 Cupredoxin TOT_010000664 81077782b64f0da5d421201c6c28b7ce 166 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 52 150 2.3E-41 T 01-11-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TOT_010000664 81077782b64f0da5d421201c6c28b7ce 166 PRINTS PR01166 Cytochrome c oxidase subunit II signature 70 91 5.4E-33 T 01-11-2018 TOT_010000664 81077782b64f0da5d421201c6c28b7ce 166 PRINTS PR01166 Cytochrome c oxidase subunit II signature 114 131 5.4E-33 T 01-11-2018 TOT_010000664 81077782b64f0da5d421201c6c28b7ce 166 PRINTS PR01166 Cytochrome c oxidase subunit II signature 94 114 5.4E-33 T 01-11-2018 TOT_010000664 81077782b64f0da5d421201c6c28b7ce 166 PRINTS PR01166 Cytochrome c oxidase subunit II signature 132 149 5.4E-33 T 01-11-2018 TOT_020000238 ca37802cd9363fa602eccf1f2a9b7bef 1191 Gene3D G3DSA:3.30.830.10 728 991 1.6E-78 T 01-11-2018 TOT_020000238 ca37802cd9363fa602eccf1f2a9b7bef 1191 SMART SM01264 643 917 1.5E-29 T 01-11-2018 IPR013578 Peptidase M16C associated GO:0006508 Reactome: R-HSA-1268020 TOT_020000238 ca37802cd9363fa602eccf1f2a9b7bef 1191 Pfam PF05193 Peptidase M16 inactive domain 344 555 2.7E-15 T 01-11-2018 IPR007863 Peptidase M16, C-terminal TOT_020000238 ca37802cd9363fa602eccf1f2a9b7bef 1191 SUPERFAMILY SSF63411 144 386 2.32E-23 T 01-11-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TOT_020000238 ca37802cd9363fa602eccf1f2a9b7bef 1191 SUPERFAMILY SSF63411 415 698 4.25E-33 T 01-11-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TOT_020000238 ca37802cd9363fa602eccf1f2a9b7bef 1191 Gene3D G3DSA:3.30.830.10 715 1164 1.6E-78 T 01-11-2018 TOT_020000238 ca37802cd9363fa602eccf1f2a9b7bef 1191 SUPERFAMILY SSF63411 739 977 5.62E-48 T 01-11-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TOT_020000238 ca37802cd9363fa602eccf1f2a9b7bef 1191 SUPERFAMILY SSF63411 1005 1160 4.23E-21 T 01-11-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TOT_020000238 ca37802cd9363fa602eccf1f2a9b7bef 1191 Gene3D G3DSA:3.30.830.10 411 662 1.0E-56 T 01-11-2018 TOT_020000238 ca37802cd9363fa602eccf1f2a9b7bef 1191 Gene3D G3DSA:3.30.830.10 109 388 3.3E-48 T 01-11-2018 TOT_020000238 ca37802cd9363fa602eccf1f2a9b7bef 1191 Pfam PF08367 Peptidase M16C associated 645 916 4.7E-35 T 01-11-2018 IPR013578 Peptidase M16C associated GO:0006508 Reactome: R-HSA-1268020 TOT_030000481 51731ae0eba0215dc5bbf8883bee890b 82 TIGRFAM TIGR00327 secE_euk_arch: protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic 21 78 7.7E-16 T 01-11-2018 IPR008158 Protein translocase SEC61 complex, gamma subunit GO:0015031|GO:0015450|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TOT_030000481 51731ae0eba0215dc5bbf8883bee890b 82 Hamap MF_00422 Protein translocase subunit SecE [secE]. 21 76 10.768 T 01-11-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TOT_030000481 51731ae0eba0215dc5bbf8883bee890b 82 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 25 77 2.1E-11 T 01-11-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TOT_030000481 51731ae0eba0215dc5bbf8883bee890b 82 SUPERFAMILY SSF103456 18 76 3.27E-12 T 01-11-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TOT_030000481 51731ae0eba0215dc5bbf8883bee890b 82 Gene3D G3DSA:1.20.5.820 19 80 7.1E-28 T 01-11-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TOT_040000022 4eb91f3e3a9788cb89d0e629790082a0 1513 Gene3D G3DSA:3.40.50.300 1227 1510 5.1E-39 T 01-11-2018 TOT_040000022 4eb91f3e3a9788cb89d0e629790082a0 1513 SUPERFAMILY SSF52540 1229 1499 2.72E-22 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_040000022 4eb91f3e3a9788cb89d0e629790082a0 1513 SUPERFAMILY SSF90123 831 1149 3.79E-20 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_040000022 4eb91f3e3a9788cb89d0e629790082a0 1513 Gene3D G3DSA:3.40.50.300 493 737 4.0E-32 T 01-11-2018 TOT_040000022 4eb91f3e3a9788cb89d0e629790082a0 1513 Pfam PF00005 ABC transporter 533 659 9.5E-11 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_040000022 4eb91f3e3a9788cb89d0e629790082a0 1513 SUPERFAMILY SSF90123 124 468 1.67E-8 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_040000022 4eb91f3e3a9788cb89d0e629790082a0 1513 Pfam PF00005 ABC transporter 1252 1430 3.3E-15 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_040000022 4eb91f3e3a9788cb89d0e629790082a0 1513 SUPERFAMILY SSF52540 526 719 1.1E-20 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_040000022 4eb91f3e3a9788cb89d0e629790082a0 1513 ProSitePatterns PS00211 ABC transporters family signature. 645 659 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_040000435 74156a07936196d36acd2c03119fb032 126 Pfam PF01250 Ribosomal protein S6 4 108 4.0E-8 T 01-11-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TOT_040000435 74156a07936196d36acd2c03119fb032 126 SUPERFAMILY SSF54995 1 109 1.14E-11 T 01-11-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TOT_040000435 74156a07936196d36acd2c03119fb032 126 Gene3D G3DSA:3.30.70.60 1 120 4.0E-10 T 01-11-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 TOT_010000284 4595f72ca0ced2b6afb2ba0e98b24080 314 Gene3D G3DSA:3.30.70.330 17 173 6.3E-9 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_010000284 4595f72ca0ced2b6afb2ba0e98b24080 314 SUPERFAMILY SSF54928 81 168 1.48E-9 T 01-11-2018 IPR035979 RNA-binding domain superfamily GO:0003676 TOT_010000329 ce90c4c1dfe24a96141552cc6bce19f8 319 Gene3D G3DSA:3.20.20.70 1 319 8.4E-84 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TOT_010000329 ce90c4c1dfe24a96141552cc6bce19f8 319 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 5 313 7.0E-59 T 01-11-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 TOT_010000329 ce90c4c1dfe24a96141552cc6bce19f8 319 SMART SM01240 3 315 2.8E-67 T 01-11-2018 TOT_010000329 ce90c4c1dfe24a96141552cc6bce19f8 319 PIRSF PIRSF036500 1 319 5.7E-122 T 01-11-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 TOT_010000329 ce90c4c1dfe24a96141552cc6bce19f8 319 SUPERFAMILY SSF51412 4 312 1.96E-72 T 01-11-2018 TOT_020000100 9d27ad30e794342289a9ffbb087bd6d5 757 Pfam PF08320 PIG-X / PBN1 430 736 4.6E-7 T 01-11-2018 IPR013233 Glycosylphosphatidylinositol-mannosyltransferase I, PIG-X/PBN1 GO:0005789|GO:0006506 Reactome: R-HSA-162710 TOT_030000558 32fc737e6ae01dce21f251802f1ed5c0 777 Gene3D G3DSA:3.30.300.20 675 757 3.0E-18 T 01-11-2018 IPR015946 K homology domain-like, alpha/beta TOT_030000558 32fc737e6ae01dce21f251802f1ed5c0 777 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 676 755 1.8E-19 T 01-11-2018 IPR032859 GTPase Der, C-terminal KH-domain-like TOT_030000558 32fc737e6ae01dce21f251802f1ed5c0 777 SUPERFAMILY SSF82653 676 750 6.93E-7 T 01-11-2018 TOT_030000558 32fc737e6ae01dce21f251802f1ed5c0 777 SUPERFAMILY SSF52540 2 269 7.61E-20 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_030000558 32fc737e6ae01dce21f251802f1ed5c0 777 Pfam PF01926 50S ribosome-binding GTPase 3 222 4.1E-16 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 TOT_040000076 393e38268b2bdeffe79b058423b9b2e1 200 SMART SM01407 57 113 4.1E-23 T 01-11-2018 IPR002715 Nascent polypeptide-associated complex NAC domain TOT_040000076 393e38268b2bdeffe79b058423b9b2e1 200 Pfam PF01849 NAC domain 57 112 2.6E-20 T 01-11-2018 IPR002715 Nascent polypeptide-associated complex NAC domain TOT_040000076 393e38268b2bdeffe79b058423b9b2e1 200 Gene3D G3DSA:1.10.8.10 161 198 7.1E-8 T 01-11-2018 TOT_040000076 393e38268b2bdeffe79b058423b9b2e1 200 PIRSF PIRSF015901 16 199 1.1E-45 T 01-11-2018 IPR016641 Nascent polypeptide-associated complex subunit alpha GO:0005854 TOT_040000076 393e38268b2bdeffe79b058423b9b2e1 200 Gene3D G3DSA:2.20.70.30 63 116 3.0E-27 T 01-11-2018 IPR038187 NAC A/B domain superfamily TOT_010001312 f099295742ad197c9f9b3217f34cc84a 131 Gene3D G3DSA:3.40.20.10 1 129 2.6E-22 T 01-11-2018 IPR029006 ADF-H/Gelsolin-like domain superfamily TOT_010001312 f099295742ad197c9f9b3217f34cc84a 131 Pfam PF00241 Cofilin/tropomyosin-type actin-binding protein 13 128 3.1E-13 T 01-11-2018 IPR002108 Actin-depolymerising factor homology domain GO:0003779|GO:0005622 TOT_010001312 f099295742ad197c9f9b3217f34cc84a 131 SUPERFAMILY SSF55753 1 126 1.04E-19 T 01-11-2018 TOT_010001312 f099295742ad197c9f9b3217f34cc84a 131 SMART SM00102 9 131 1.4E-4 T 01-11-2018 IPR002108 Actin-depolymerising factor homology domain GO:0003779|GO:0005622 TOT_010001248 24e13f9d4077529b79a17b6400f3dbd8 130 ProSitePatterns PS00936 Ribosomal protein L35 signature. 69 95 - T 01-11-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOT_010001248 24e13f9d4077529b79a17b6400f3dbd8 130 PRINTS PR00064 Ribosomal protein L35 signature 85 99 8.7E-5 T 01-11-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TOT_010001248 24e13f9d4077529b79a17b6400f3dbd8 130 PRINTS PR00064 Ribosomal protein L35 signature 67 84 8.7E-5 T 01-11-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TOT_010001248 24e13f9d4077529b79a17b6400f3dbd8 130 SUPERFAMILY SSF143034 67 121 1.7E-11 T 01-11-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TOT_010001248 24e13f9d4077529b79a17b6400f3dbd8 130 Pfam PF01632 Ribosomal protein L35 67 115 4.1E-9 T 01-11-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TOT_010001248 24e13f9d4077529b79a17b6400f3dbd8 130 Gene3D G3DSA:2.40.50.530 66 128 2.4E-10 T 01-11-2018 TOT_040000740 72610b070009045f5fd9ef69b8a0bd7d 872 SUPERFAMILY SSF52540 362 626 1.38E-31 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_040000740 72610b070009045f5fd9ef69b8a0bd7d 872 Pfam PF01926 50S ribosome-binding GTPase 495 625 1.8E-14 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 TOT_030000426 84f72f7637480b589682c669e6da6cb1 67 ProSitePatterns PS00961 Ribosomal protein S28e signature. 58 66 - T 01-11-2018 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_030000426 84f72f7637480b589682c669e6da6cb1 67 Gene3D G3DSA:2.40.50.140 1 67 2.8E-34 T 01-11-2018 TOT_030000426 84f72f7637480b589682c669e6da6cb1 67 Pfam PF01200 Ribosomal protein S28e 2 66 1.1E-32 T 01-11-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_030000426 84f72f7637480b589682c669e6da6cb1 67 SUPERFAMILY SSF50249 1 67 4.03E-24 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold TOT_030000426 84f72f7637480b589682c669e6da6cb1 67 ProDom PD005541 RIBOSOMAL RIBONUCLEOPROTEIN 40S S28 S28E 30S ACETYLATION S33 S33 CG15527 1 48 1.0E-20 T 01-11-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_030000426 84f72f7637480b589682c669e6da6cb1 67 Hamap MF_00292 30S ribosomal protein S28e [rps28e]. 1 67 20.443 T 01-11-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_020000722 98d6c43a4e37e86d78af7a7c872cb73b 1516 SUPERFAMILY SSF52540 1204 1503 1.07E-25 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000722 98d6c43a4e37e86d78af7a7c872cb73b 1516 SMART SM00382 543 743 2.8 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000722 98d6c43a4e37e86d78af7a7c872cb73b 1516 SMART SM00382 1262 1488 0.31 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000722 98d6c43a4e37e86d78af7a7c872cb73b 1516 SUPERFAMILY SSF52540 509 720 1.36E-22 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000722 98d6c43a4e37e86d78af7a7c872cb73b 1516 SUPERFAMILY SSF90123 833 1143 2.75E-14 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000722 98d6c43a4e37e86d78af7a7c872cb73b 1516 Gene3D G3DSA:3.40.50.300 1224 1511 5.5E-42 T 01-11-2018 TOT_020000722 98d6c43a4e37e86d78af7a7c872cb73b 1516 Pfam PF00005 ABC transporter 534 661 4.7E-13 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000722 98d6c43a4e37e86d78af7a7c872cb73b 1516 Gene3D G3DSA:3.40.50.300 488 737 7.7E-34 T 01-11-2018 TOT_020000722 98d6c43a4e37e86d78af7a7c872cb73b 1516 Pfam PF00005 ABC transporter 1254 1433 1.1E-16 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000722 98d6c43a4e37e86d78af7a7c872cb73b 1516 ProSitePatterns PS00211 ABC transporters family signature. 646 660 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_010001171 24a04d0b49897bc16789391b32da3d0a 1612 Pfam PF04385 Domain of unknown function, DUF529 706 752 2.4E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010001171 24a04d0b49897bc16789391b32da3d0a 1612 Pfam PF04385 Domain of unknown function, DUF529 53 107 5.3E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000606 de90bffdcc80d34fcb601e44c35e9320 355 Pfam PF12572 Protein of unknown function (DUF3752) 277 345 2.4E-5 T 01-11-2018 IPR022226 Protein of unknown function DUF3752 TOT_030000384 3d96c0f2951a9cc69154126c1a6d135c 1932 Pfam PF12234 RAVE protein 1 C terminal 1283 1428 6.3E-22 T 01-11-2018 IPR022033 RAVE complex protein Rav1 C-terminal TOT_040000915 771a916583eac90947854b915dde64e9 288 Gene3D G3DSA:1.10.287.110 2 79 1.1E-7 T 01-11-2018 IPR036869 Chaperone J-domain superfamily TOT_040000915 771a916583eac90947854b915dde64e9 288 SUPERFAMILY SSF46565 25 77 2.88E-7 T 01-11-2018 IPR036869 Chaperone J-domain superfamily TOT_040000915 771a916583eac90947854b915dde64e9 288 Pfam PF00226 DnaJ domain 25 77 9.5E-7 T 01-11-2018 IPR001623 DnaJ domain TOT_010000104 1077f41fb6ca46c361e16a9d79066a57 1510 Gene3D G3DSA:3.40.50.300 1229 1508 9.1E-43 T 01-11-2018 TOT_010000104 1077f41fb6ca46c361e16a9d79066a57 1510 SUPERFAMILY SSF90123 844 1155 1.23E-22 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_010000104 1077f41fb6ca46c361e16a9d79066a57 1510 SUPERFAMILY SSF52540 1226 1496 2.43E-26 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010000104 1077f41fb6ca46c361e16a9d79066a57 1510 SUPERFAMILY SSF52540 526 708 1.17E-23 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010000104 1077f41fb6ca46c361e16a9d79066a57 1510 Pfam PF00005 ABC transporter 533 659 4.4E-13 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_010000104 1077f41fb6ca46c361e16a9d79066a57 1510 Pfam PF00005 ABC transporter 1255 1428 3.6E-18 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_010000104 1077f41fb6ca46c361e16a9d79066a57 1510 ProSitePatterns PS00211 ABC transporters family signature. 645 659 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_010000104 1077f41fb6ca46c361e16a9d79066a57 1510 Gene3D G3DSA:3.40.50.300 499 740 1.7E-35 T 01-11-2018 TOT_010000104 1077f41fb6ca46c361e16a9d79066a57 1510 Gene3D G3DSA:1.20.1560.10 811 1158 1.3E-11 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_010000104 1077f41fb6ca46c361e16a9d79066a57 1510 SMART SM00382 1264 1482 0.12 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_010000104 1077f41fb6ca46c361e16a9d79066a57 1510 SMART SM00382 542 742 3.1 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_030000563 e2f463a2aab3c210317e0ae1e5b5837d 438 ProSitePatterns PS00640 Eukaryotic thiol (cysteine) proteases asparagine active site. 397 416 - T 01-11-2018 IPR025661 Cysteine peptidase, asparagine active site TOT_030000563 e2f463a2aab3c210317e0ae1e5b5837d 438 Pfam PF00112 Papain family cysteine protease 228 430 1.0E-57 T 01-11-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 TOT_030000563 e2f463a2aab3c210317e0ae1e5b5837d 438 SMART SM00645 226 436 5.4E-73 T 01-11-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 TOT_030000563 e2f463a2aab3c210317e0ae1e5b5837d 438 SUPERFAMILY SSF54001 115 436 2.88E-81 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily TOT_030000563 e2f463a2aab3c210317e0ae1e5b5837d 438 Pfam PF08246 Cathepsin propeptide inhibitor domain (I29) 118 173 2.5E-11 T 01-11-2018 IPR013201 Cathepsin propeptide inhibitor domain (I29) Reactome: R-HSA-2132295 TOT_030000563 e2f463a2aab3c210317e0ae1e5b5837d 438 Gene3D G3DSA:3.90.70.10 90 437 1.0E-82 T 01-11-2018 TOT_030000563 e2f463a2aab3c210317e0ae1e5b5837d 438 SMART SM00848 118 173 1.4E-15 T 01-11-2018 IPR013201 Cathepsin propeptide inhibitor domain (I29) Reactome: R-HSA-2132295 TOT_030000563 e2f463a2aab3c210317e0ae1e5b5837d 438 PRINTS PR00705 Papain cysteine protease (C1) family signature 397 403 3.6E-7 T 01-11-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 TOT_030000563 e2f463a2aab3c210317e0ae1e5b5837d 438 PRINTS PR00705 Papain cysteine protease (C1) family signature 245 260 3.6E-7 T 01-11-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 TOT_030000563 e2f463a2aab3c210317e0ae1e5b5837d 438 PRINTS PR00705 Papain cysteine protease (C1) family signature 380 390 3.6E-7 T 01-11-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 TOT_030000578 f6d9e0860e5d752cc66b2a05d1f43cb1 1563 Pfam PF07422 Sexual stage antigen s48/45 domain 1437 1549 1.1E-14 T 01-11-2018 IPR010884 6-Cysteine (6-Cys) domain TOT_030000578 f6d9e0860e5d752cc66b2a05d1f43cb1 1563 Gene3D G3DSA:2.60.40.2860 1436 1563 6.0E-20 T 01-11-2018 IPR038160 6-Cysteine (6-Cys) domain superfamily TOT_030000578 f6d9e0860e5d752cc66b2a05d1f43cb1 1563 SUPERFAMILY SSF81995 953 1080 5.49E-7 T 01-11-2018 TOT_020000105 411b0a12aa74e37683850782d5f1ad50 1432 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 630 732 3.2E-10 T 01-11-2018 TOT_020000105 411b0a12aa74e37683850782d5f1ad50 1432 Gene3D G3DSA:2.120.10.80 311 414 2.1E-6 T 01-11-2018 IPR015915 Kelch-type beta propeller GO:0005515 TOT_020000105 411b0a12aa74e37683850782d5f1ad50 1432 SUPERFAMILY SSF55874 626 736 4.45E-11 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TOT_020000105 411b0a12aa74e37683850782d5f1ad50 1432 Gene3D G3DSA:2.120.10.80 150 292 3.9E-12 T 01-11-2018 IPR015915 Kelch-type beta propeller GO:0005515 TOT_020000105 411b0a12aa74e37683850782d5f1ad50 1432 Gene3D G3DSA:3.30.565.10 611 746 7.7E-9 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TOT_020000105 411b0a12aa74e37683850782d5f1ad50 1432 SUPERFAMILY SSF117281 160 411 5.23E-27 T 01-11-2018 IPR015915 Kelch-type beta propeller GO:0005515 TOT_020000105 411b0a12aa74e37683850782d5f1ad50 1432 Pfam PF13415 Galactose oxidase, central domain 324 367 5.1E-5 T 01-11-2018 TOT_020000105 411b0a12aa74e37683850782d5f1ad50 1432 Pfam PF13418 Galactose oxidase, central domain 236 278 4.3E-6 T 01-11-2018 TOT_030000506 bb85a51150ce32912d4cc5479339d60e 554 Gene3D G3DSA:3.40.50.1820 131 286 1.0E-10 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold TOT_030000506 bb85a51150ce32912d4cc5479339d60e 554 SUPERFAMILY SSF53474 126 318 5.85E-14 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold TOT_030000506 bb85a51150ce32912d4cc5479339d60e 554 Pfam PF05057 Putative serine esterase (DUF676) 129 313 1.1E-10 T 01-11-2018 IPR007751 Domain of unknown function DUF676, lipase-like TOT_020000328 c03a62531e8c75e2a3d8bb9eac4f2981 1517 Gene3D G3DSA:1.20.1560.10 817 1152 4.7E-13 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000328 c03a62531e8c75e2a3d8bb9eac4f2981 1517 Pfam PF00005 ABC transporter 531 658 1.3E-10 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000328 c03a62531e8c75e2a3d8bb9eac4f2981 1517 Gene3D G3DSA:3.40.50.300 490 775 3.6E-35 T 01-11-2018 TOT_020000328 c03a62531e8c75e2a3d8bb9eac4f2981 1517 SUPERFAMILY SSF90123 829 1152 8.37E-26 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000328 c03a62531e8c75e2a3d8bb9eac4f2981 1517 ProSitePatterns PS00211 ABC transporters family signature. 643 657 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_020000328 c03a62531e8c75e2a3d8bb9eac4f2981 1517 SMART SM00382 540 740 5.3E-4 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000328 c03a62531e8c75e2a3d8bb9eac4f2981 1517 SMART SM00382 1259 1480 0.53 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000328 c03a62531e8c75e2a3d8bb9eac4f2981 1517 SUPERFAMILY SSF52540 1220 1505 3.24E-27 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000328 c03a62531e8c75e2a3d8bb9eac4f2981 1517 Gene3D G3DSA:3.40.50.300 1221 1513 3.8E-43 T 01-11-2018 TOT_020000328 c03a62531e8c75e2a3d8bb9eac4f2981 1517 Pfam PF00005 ABC transporter 1250 1435 1.1E-16 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000328 c03a62531e8c75e2a3d8bb9eac4f2981 1517 SUPERFAMILY SSF52540 524 709 7.79E-23 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_040000827 f87b44fe08a8e7ee9db6d6e94ea36c90 747 Pfam PF04385 Domain of unknown function, DUF529 631 689 1.9E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000503 bd38b88c9ec8a9b835bd9d73917060d4 497 PRINTS PR00625 DnaJ domain signature 107 125 2.5E-15 T 01-11-2018 IPR001623 DnaJ domain TOT_020000503 bd38b88c9ec8a9b835bd9d73917060d4 497 PRINTS PR00625 DnaJ domain signature 125 140 2.5E-15 T 01-11-2018 IPR001623 DnaJ domain TOT_020000503 bd38b88c9ec8a9b835bd9d73917060d4 497 PRINTS PR00625 DnaJ domain signature 141 161 2.5E-15 T 01-11-2018 IPR001623 DnaJ domain TOT_020000503 bd38b88c9ec8a9b835bd9d73917060d4 497 Pfam PF14308 X-domain of DnaJ-containing 258 476 6.7E-34 T 01-11-2018 IPR026894 DNAJ-containing protein, X-domain TOT_020000503 bd38b88c9ec8a9b835bd9d73917060d4 497 ProSitePatterns PS00636 Nt-dnaJ domain signature. 146 165 - T 01-11-2018 IPR018253 DnaJ domain, conserved site TOT_020000503 bd38b88c9ec8a9b835bd9d73917060d4 497 Gene3D G3DSA:1.10.287.110 103 198 5.6E-25 T 01-11-2018 IPR036869 Chaperone J-domain superfamily TOT_020000503 bd38b88c9ec8a9b835bd9d73917060d4 497 Pfam PF00226 DnaJ domain 106 166 5.2E-23 T 01-11-2018 IPR001623 DnaJ domain TOT_020000503 bd38b88c9ec8a9b835bd9d73917060d4 497 SUPERFAMILY SSF46565 106 193 5.89E-24 T 01-11-2018 IPR036869 Chaperone J-domain superfamily TOT_020000503 bd38b88c9ec8a9b835bd9d73917060d4 497 SMART SM00271 104 161 1.2E-22 T 01-11-2018 IPR001623 DnaJ domain TOT_030000841 7da922311a0015c51e09dd2534631eff 1981 Pfam PF04385 Domain of unknown function, DUF529 1858 1936 5.1E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010001184 359af778c0005beaac56f6eb1b775006 98 Pfam PF01221 Dynein light chain type 1 15 96 1.7E-36 T 01-11-2018 IPR001372 Dynein light chain, type 1/2 GO:0007017|GO:0030286 TOT_010001184 359af778c0005beaac56f6eb1b775006 98 Gene3D G3DSA:3.30.740.10 5 97 3.8E-39 T 01-11-2018 IPR037177 Dynein light chain superfamily GO:0007017|GO:0030286 TOT_010001184 359af778c0005beaac56f6eb1b775006 98 SUPERFAMILY SSF54648 8 98 2.75E-36 T 01-11-2018 IPR037177 Dynein light chain superfamily GO:0007017|GO:0030286 TOT_010001184 359af778c0005beaac56f6eb1b775006 98 SMART SM01375 10 97 7.0E-48 T 01-11-2018 IPR001372 Dynein light chain, type 1/2 GO:0007017|GO:0030286 TOT_010001184 359af778c0005beaac56f6eb1b775006 98 ProSitePatterns PS01239 Dynein light chain type 1 signature. 64 78 - T 01-11-2018 IPR019763 Dynein light chain, type 1/2, conserved site GO:0005875|GO:0007017 Reactome: R-HSA-141444|Reactome: R-HSA-1632852|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-5620924|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811436|Reactome: R-HSA-68877 TOT_010000595 1b03e415ced1488347af542180db581c 165 Pfam PF04385 Domain of unknown function, DUF529 67 126 6.6E-8 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000690 e940fc78768e697cb97a8eca6c62931a 3062 SMART SM00220 1902 2603 0.0036 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOT_010000690 e940fc78768e697cb97a8eca6c62931a 3062 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 2017 2029 - T 01-11-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TOT_010000690 e940fc78768e697cb97a8eca6c62931a 3062 SUPERFAMILY SSF56112 1779 2142 2.69E-11 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily TOT_010000690 e940fc78768e697cb97a8eca6c62931a 3062 SUPERFAMILY SSF56112 2411 2612 6.18E-9 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily TOT_010000008 ae930a7fd5c4f5ce3d212c1330553948 1522 SUPERFAMILY SSF90123 832 1142 9.16E-24 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_010000008 ae930a7fd5c4f5ce3d212c1330553948 1522 Pfam PF00005 ABC transporter 533 659 2.0E-12 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_010000008 ae930a7fd5c4f5ce3d212c1330553948 1522 Gene3D G3DSA:3.40.50.300 1221 1517 6.6E-42 T 01-11-2018 TOT_010000008 ae930a7fd5c4f5ce3d212c1330553948 1522 Gene3D G3DSA:1.20.1560.10 828 1155 5.8E-6 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_010000008 ae930a7fd5c4f5ce3d212c1330553948 1522 ProSitePatterns PS00211 ABC transporters family signature. 645 659 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_010000008 ae930a7fd5c4f5ce3d212c1330553948 1522 Pfam PF00005 ABC transporter 1253 1440 2.4E-17 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_010000008 ae930a7fd5c4f5ce3d212c1330553948 1522 SMART SM00382 542 742 0.59 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_010000008 ae930a7fd5c4f5ce3d212c1330553948 1522 SMART SM00382 1262 1512 0.026 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_010000008 ae930a7fd5c4f5ce3d212c1330553948 1522 Gene3D G3DSA:3.40.50.300 487 736 1.0E-34 T 01-11-2018 TOT_010000008 ae930a7fd5c4f5ce3d212c1330553948 1522 SUPERFAMILY SSF52540 1226 1509 3.86E-25 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010000008 ae930a7fd5c4f5ce3d212c1330553948 1522 SUPERFAMILY SSF52540 507 723 1.66E-23 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010000008 ae930a7fd5c4f5ce3d212c1330553948 1522 SUPERFAMILY SSF90123 123 475 1.28E-5 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_030000697 bae0ab49f9f34543da55190144784256 136 ProSitePatterns PS00322 Histone H3 signature 1. 15 21 - T 01-11-2018 IPR000164 Histone H3/CENP-A GO:0000786|GO:0003677 TOT_030000697 bae0ab49f9f34543da55190144784256 136 PRINTS PR00622 Histone H3 signature 114 135 2.6E-83 T 01-11-2018 IPR000164 Histone H3/CENP-A GO:0000786|GO:0003677 TOT_030000697 bae0ab49f9f34543da55190144784256 136 PRINTS PR00622 Histone H3 signature 34 55 2.6E-83 T 01-11-2018 IPR000164 Histone H3/CENP-A GO:0000786|GO:0003677 TOT_030000697 bae0ab49f9f34543da55190144784256 136 PRINTS PR00622 Histone H3 signature 80 98 2.6E-83 T 01-11-2018 IPR000164 Histone H3/CENP-A GO:0000786|GO:0003677 TOT_030000697 bae0ab49f9f34543da55190144784256 136 PRINTS PR00622 Histone H3 signature 98 114 2.6E-83 T 01-11-2018 IPR000164 Histone H3/CENP-A GO:0000786|GO:0003677 TOT_030000697 bae0ab49f9f34543da55190144784256 136 PRINTS PR00622 Histone H3 signature 3 17 2.6E-83 T 01-11-2018 IPR000164 Histone H3/CENP-A GO:0000786|GO:0003677 TOT_030000697 bae0ab49f9f34543da55190144784256 136 PRINTS PR00622 Histone H3 signature 17 31 2.6E-83 T 01-11-2018 IPR000164 Histone H3/CENP-A GO:0000786|GO:0003677 TOT_030000697 bae0ab49f9f34543da55190144784256 136 PRINTS PR00622 Histone H3 signature 58 75 2.6E-83 T 01-11-2018 IPR000164 Histone H3/CENP-A GO:0000786|GO:0003677 TOT_030000697 bae0ab49f9f34543da55190144784256 136 ProSitePatterns PS00959 Histone H3 signature 2. 67 75 - T 01-11-2018 IPR000164 Histone H3/CENP-A GO:0000786|GO:0003677 TOT_030000697 bae0ab49f9f34543da55190144784256 136 SMART SM00428 34 136 8.5E-71 T 01-11-2018 IPR000164 Histone H3/CENP-A GO:0000786|GO:0003677 TOT_030000697 bae0ab49f9f34543da55190144784256 136 Pfam PF00125 Core histone H2A/H2B/H3/H4 1 132 5.1E-51 T 01-11-2018 IPR007125 Histone H2A/H2B/H3 GO:0000786|GO:0003677 TOT_030000697 bae0ab49f9f34543da55190144784256 136 Gene3D G3DSA:1.10.20.10 2 136 2.5E-76 T 01-11-2018 IPR009072 Histone-fold GO:0046982 TOT_030000697 bae0ab49f9f34543da55190144784256 136 SUPERFAMILY SSF47113 2 133 9.39E-54 T 01-11-2018 IPR009072 Histone-fold GO:0046982 TOT_040000826 36e71f10b84ed1b7d4c157f93a49c05b 647 Pfam PF04385 Domain of unknown function, DUF529 88 158 2.5E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000826 36e71f10b84ed1b7d4c157f93a49c05b 647 Pfam PF04385 Domain of unknown function, DUF529 558 617 9.5E-7 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000783 a94913d4ccad3be021d12c218b112fd6 373 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 5 346 27.712 T 01-11-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 TOT_010000783 a94913d4ccad3be021d12c218b112fd6 373 Pfam PF01728 FtsJ-like methyltransferase 21 345 3.5E-54 T 01-11-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 TOT_010000783 a94913d4ccad3be021d12c218b112fd6 373 SUPERFAMILY SSF53335 122 347 3.11E-19 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOT_020001008 9b1bb8e4d76eefedd053d32087627305 226 SMART SM01405 1 126 3.1E-80 T 01-11-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_020001008 9b1bb8e4d76eefedd053d32087627305 226 Pfam PF01092 Ribosomal protein S6e 1 126 4.5E-57 T 01-11-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_020001008 9b1bb8e4d76eefedd053d32087627305 226 ProSitePatterns PS00578 Ribosomal protein S6e signature. 52 63 - T 01-11-2018 IPR018282 Ribosomal protein S6e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_020001008 9b1bb8e4d76eefedd053d32087627305 226 PIRSF PIRSF002129 1 225 2.7E-102 T 01-11-2018 IPR014401 Ribosomal protein S6, eukaryotic GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_040000502 f5d2e33c3008f5666007b6c139f97c19 107 PRINTS PR00621 Histone H2B signature 59 76 1.7E-43 T 01-11-2018 IPR000558 Histone H2B GO:0000786|GO:0003677 TOT_040000502 f5d2e33c3008f5666007b6c139f97c19 107 PRINTS PR00621 Histone H2B signature 76 89 1.7E-43 T 01-11-2018 IPR000558 Histone H2B GO:0000786|GO:0003677 TOT_040000502 f5d2e33c3008f5666007b6c139f97c19 107 PRINTS PR00621 Histone H2B signature 18 36 1.7E-43 T 01-11-2018 IPR000558 Histone H2B GO:0000786|GO:0003677 TOT_040000502 f5d2e33c3008f5666007b6c139f97c19 107 PRINTS PR00621 Histone H2B signature 37 57 1.7E-43 T 01-11-2018 IPR000558 Histone H2B GO:0000786|GO:0003677 TOT_040000502 f5d2e33c3008f5666007b6c139f97c19 107 PRINTS PR00621 Histone H2B signature 89 102 1.7E-43 T 01-11-2018 IPR000558 Histone H2B GO:0000786|GO:0003677 TOT_040000502 f5d2e33c3008f5666007b6c139f97c19 107 SUPERFAMILY SSF47113 6 103 1.71E-44 T 01-11-2018 IPR009072 Histone-fold GO:0046982 TOT_040000502 f5d2e33c3008f5666007b6c139f97c19 107 SMART SM00427 8 104 2.6E-63 T 01-11-2018 IPR000558 Histone H2B GO:0000786|GO:0003677 TOT_040000502 f5d2e33c3008f5666007b6c139f97c19 107 Gene3D G3DSA:1.10.20.10 1 106 3.5E-51 T 01-11-2018 IPR009072 Histone-fold GO:0046982 TOT_040000502 f5d2e33c3008f5666007b6c139f97c19 107 Pfam PF00125 Core histone H2A/H2B/H3/H4 8 81 1.7E-15 T 01-11-2018 IPR007125 Histone H2A/H2B/H3 GO:0000786|GO:0003677 TOT_040000502 f5d2e33c3008f5666007b6c139f97c19 107 ProSitePatterns PS00357 Histone H2B signature. 73 95 - T 01-11-2018 IPR000558 Histone H2B GO:0000786|GO:0003677 TOT_020000299 3b8bc217418a1373c50245ab7e58dee1 1048 Pfam PF13634 Nucleoporin FG repeat region 770 844 2.2E-4 T 01-11-2018 IPR025574 Nucleoporin FG repeat TOT_020000299 3b8bc217418a1373c50245ab7e58dee1 1048 Pfam PF13634 Nucleoporin FG repeat region 628 719 6.8 T 01-11-2018 IPR025574 Nucleoporin FG repeat TOT_020000299 3b8bc217418a1373c50245ab7e58dee1 1048 Pfam PF13634 Nucleoporin FG repeat region 960 1025 2.2 T 01-11-2018 IPR025574 Nucleoporin FG repeat TOT_020000299 3b8bc217418a1373c50245ab7e58dee1 1048 Pfam PF13634 Nucleoporin FG repeat region 429 514 0.0025 T 01-11-2018 IPR025574 Nucleoporin FG repeat TOT_010000787 f91164745fd802357d47f1c4837d459c 1046 SMART SM00355 429 455 10.0 T 01-11-2018 IPR013087 Zinc finger C2H2-type GO:0003676 TOT_010000787 f91164745fd802357d47f1c4837d459c 1046 SMART SM00355 399 428 8.3 T 01-11-2018 IPR013087 Zinc finger C2H2-type GO:0003676 TOT_010000787 f91164745fd802357d47f1c4837d459c 1046 SMART SM00355 375 398 220.0 T 01-11-2018 IPR013087 Zinc finger C2H2-type GO:0003676 TOT_020000497 d35d923c870093bc99cc3e5722ed2041 346 SUPERFAMILY SSF57850 153 221 1.57E-13 T 01-11-2018 TOT_020000497 d35d923c870093bc99cc3e5722ed2041 346 Gene3D G3DSA:3.30.390.130 208 343 1.6E-34 T 01-11-2018 IPR039399 Deltex, C-terminal domain superfamily MetaCyc: PWY-7511 TOT_020000497 d35d923c870093bc99cc3e5722ed2041 346 Gene3D G3DSA:3.30.40.10 123 205 5.5E-9 T 01-11-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type TOT_020000497 d35d923c870093bc99cc3e5722ed2041 346 SMART SM00184 158 201 1.1E-5 T 01-11-2018 IPR001841 Zinc finger, RING-type TOT_020000497 d35d923c870093bc99cc3e5722ed2041 346 Pfam PF13639 Ring finger domain 157 202 5.2E-8 T 01-11-2018 IPR001841 Zinc finger, RING-type TOT_040000057 d18a53321c13e5fce59b39064efd7da7 1141 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 410 645 1.9E-14 T 01-11-2018 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 TOT_040000057 d18a53321c13e5fce59b39064efd7da7 1141 SMART SM00839 704 1010 1.0E-72 T 01-11-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TOT_040000057 d18a53321c13e5fce59b39064efd7da7 1141 SUPERFAMILY SSF53223 515 715 8.96E-21 T 01-11-2018 TOT_040000057 d18a53321c13e5fce59b39064efd7da7 1141 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 703 1010 5.0E-42 T 01-11-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TOT_040000057 d18a53321c13e5fce59b39064efd7da7 1141 SUPERFAMILY SSF51735 707 1021 5.12E-30 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily TOT_020000088 6e39fce277c386c122cd51b0cfacd891 364 SUPERFAMILY SSF57667 21 57 3.18E-5 T 01-11-2018 IPR036236 Zinc finger C2H2 superfamily TOT_020000088 6e39fce277c386c122cd51b0cfacd891 364 SMART SM00451 21 55 0.003 T 01-11-2018 IPR003604 Matrin/U1-C-like, C2H2-type zinc finger GO:0003676|GO:0008270 TOT_020000088 6e39fce277c386c122cd51b0cfacd891 364 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 176 198 - T 01-11-2018 IPR013087 Zinc finger C2H2-type GO:0003676 TOT_020000088 6e39fce277c386c122cd51b0cfacd891 364 Pfam PF12756 C2H2 type zinc-finger (2 copies) 125 217 2.6E-22 T 01-11-2018 TOT_010000041 5c0b27c72c367200bd887c9d03764a0e 489 SUPERFAMILY SSF53067 31 253 2.96E-47 T 01-11-2018 TOT_010000041 5c0b27c72c367200bd887c9d03764a0e 489 PRINTS PR00475 Hexokinase family signature 178 203 6.0E-49 T 01-11-2018 TOT_010000041 5c0b27c72c367200bd887c9d03764a0e 489 PRINTS PR00475 Hexokinase family signature 395 417 6.0E-49 T 01-11-2018 TOT_010000041 5c0b27c72c367200bd887c9d03764a0e 489 PRINTS PR00475 Hexokinase family signature 467 483 6.0E-49 T 01-11-2018 TOT_010000041 5c0b27c72c367200bd887c9d03764a0e 489 PRINTS PR00475 Hexokinase family signature 235 251 6.0E-49 T 01-11-2018 TOT_010000041 5c0b27c72c367200bd887c9d03764a0e 489 PRINTS PR00475 Hexokinase family signature 262 276 6.0E-49 T 01-11-2018 TOT_010000041 5c0b27c72c367200bd887c9d03764a0e 489 PRINTS PR00475 Hexokinase family signature 99 115 6.0E-49 T 01-11-2018 TOT_010000041 5c0b27c72c367200bd887c9d03764a0e 489 PRINTS PR00475 Hexokinase family signature 319 341 6.0E-49 T 01-11-2018 TOT_010000041 5c0b27c72c367200bd887c9d03764a0e 489 SUPERFAMILY SSF53067 260 484 9.93E-52 T 01-11-2018 TOT_010000041 5c0b27c72c367200bd887c9d03764a0e 489 Gene3D G3DSA:3.40.367.20 49 470 2.4E-101 T 01-11-2018 TOT_010000041 5c0b27c72c367200bd887c9d03764a0e 489 Pfam PF03727 Hexokinase 261 483 8.5E-45 T 01-11-2018 IPR022673 Hexokinase, C-terminal GO:0005524|GO:0005975|GO:0016773 KEGG: 00010+2.7.1.1|KEGG: 00051+2.7.1.1|KEGG: 00052+2.7.1.1|KEGG: 00500+2.7.1.1|KEGG: 00520+2.7.1.1|KEGG: 00521+2.7.1.1|KEGG: 00524+2.7.1.1|Reactome: R-HSA-70171 TOT_010000041 5c0b27c72c367200bd887c9d03764a0e 489 Gene3D G3DSA:3.30.420.40 65 482 2.4E-101 T 01-11-2018 TOT_010000041 5c0b27c72c367200bd887c9d03764a0e 489 Pfam PF00349 Hexokinase 33 251 8.6E-48 T 01-11-2018 IPR022672 Hexokinase, N-terminal GO:0005524|GO:0005975|GO:0016773 KEGG: 00010+2.7.1.1|KEGG: 00051+2.7.1.1|KEGG: 00052+2.7.1.1|KEGG: 00500+2.7.1.1|KEGG: 00520+2.7.1.1|KEGG: 00521+2.7.1.1|KEGG: 00524+2.7.1.1|Reactome: R-HSA-70171 TOT_020000667 240006bed335f075a969ec472c9ee3a5 438 Pfam PF12400 STIMATE family 356 432 5.0E-15 T 01-11-2018 IPR022127 Store-operated calcium entry regulator STIMATE/YPL162C TOT_020001043 b129d5591734eab2d25942a9afddcb90 369 Hamap MF_03007 Eukaryotic translation initiation factor 3 subunit H [EIF3H]. 12 368 38.656 T 01-11-2018 IPR027524 Eukaryotic translation initiation factor 3 subunit H GO:0003743|GO:0005737|GO:0005852 Reactome: R-HSA-156827|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706 TOT_020001043 b129d5591734eab2d25942a9afddcb90 369 Gene3D G3DSA:3.40.140.10 11 244 3.2E-31 T 01-11-2018 TOT_020001043 b129d5591734eab2d25942a9afddcb90 369 Pfam PF01398 JAB1/Mov34/MPN/PAD-1 ubiquitin protease 38 143 1.3E-5 T 01-11-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 TOT_030000702 91ae04f7c5c46ef3aa4a77925aa03ff4 1345 Pfam PF04385 Domain of unknown function, DUF529 284 349 9.3E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010001282 721f9448b467047b50016be30e192886 627 Pfam PF03085 Rhoptry-associated protein 1 (RAP-1) 287 450 5.3E-23 T 01-11-2018 IPR004318 Rhoptry-associated protein 1 TOT_010001282 721f9448b467047b50016be30e192886 627 Pfam PF03085 Rhoptry-associated protein 1 (RAP-1) 45 283 1.8E-66 T 01-11-2018 IPR004318 Rhoptry-associated protein 1 TOT_010001215 5ea19b5f1c9655157c0fd2f58ce59ad7 1180 Gene3D G3DSA:1.10.150.60 1 103 1.9E-6 T 01-11-2018 IPR036431 ARID DNA-binding domain superfamily GO:0003677 TOT_010001215 5ea19b5f1c9655157c0fd2f58ce59ad7 1180 SUPERFAMILY SSF46774 2 69 1.16E-5 T 01-11-2018 IPR036431 ARID DNA-binding domain superfamily GO:0003677 TOT_010001215 5ea19b5f1c9655157c0fd2f58ce59ad7 1180 Pfam PF01388 ARID/BRIGHT DNA binding domain 3 68 6.2E-6 T 01-11-2018 IPR001606 ARID DNA-binding domain GO:0003677 TOT_010000271 c73044b0efc11e28b683602a0d202751 78 ProDom PD010361 RIBOSOMAL RIBONUCLEOPROTEIN L38 60S L38 L38E FAMILY STRAIN MULTIGENE NRRL 1 69 9.0E-21 T 01-11-2018 IPR002675 Ribosomal protein L38e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_010000271 c73044b0efc11e28b683602a0d202751 78 Gene3D G3DSA:3.30.720.90 1 78 4.4E-23 T 01-11-2018 IPR038464 Ribosomal protein L38e superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_010000271 c73044b0efc11e28b683602a0d202751 78 Pfam PF01781 Ribosomal L38e protein family 2 73 7.2E-23 T 01-11-2018 IPR002675 Ribosomal protein L38e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_040000350 883c0721dba56bc1ed2afe8db43d9dbe 272 Pfam PF00071 Ras family 114 233 5.2E-30 T 01-11-2018 IPR001806 Small GTPase GO:0003924|GO:0005525 TOT_040000350 883c0721dba56bc1ed2afe8db43d9dbe 272 Pfam PF00071 Ras family 7 60 1.9E-9 T 01-11-2018 IPR001806 Small GTPase GO:0003924|GO:0005525 TOT_040000350 883c0721dba56bc1ed2afe8db43d9dbe 272 SMART SM00174 8 230 5.0E-9 T 01-11-2018 TOT_040000350 883c0721dba56bc1ed2afe8db43d9dbe 272 SMART SM00173 3 235 1.1E-7 T 01-11-2018 TOT_040000350 883c0721dba56bc1ed2afe8db43d9dbe 272 SMART SM00175 6 235 7.6E-42 T 01-11-2018 TOT_040000350 883c0721dba56bc1ed2afe8db43d9dbe 272 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 228 6.5E-21 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TOT_040000350 883c0721dba56bc1ed2afe8db43d9dbe 272 PRINTS PR00449 Transforming protein P21 ras signature 6 27 7.2E-18 T 01-11-2018 TOT_040000350 883c0721dba56bc1ed2afe8db43d9dbe 272 PRINTS PR00449 Transforming protein P21 ras signature 172 185 7.2E-18 T 01-11-2018 TOT_040000350 883c0721dba56bc1ed2afe8db43d9dbe 272 PRINTS PR00449 Transforming protein P21 ras signature 210 232 7.2E-18 T 01-11-2018 TOT_040000350 883c0721dba56bc1ed2afe8db43d9dbe 272 SUPERFAMILY SSF52540 3 248 1.4E-44 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020001102 7788083c0973a4d09150d950c60f53bb 376 SMART SM00268 6 376 4.1E-228 T 01-11-2018 IPR004000 Actin family TOT_020001102 7788083c0973a4d09150d950c60f53bb 376 Pfam PF00022 Actin 4 376 4.7E-143 T 01-11-2018 IPR004000 Actin family TOT_020001102 7788083c0973a4d09150d950c60f53bb 376 ProSitePatterns PS01132 Actins and actin-related proteins signature. 105 117 - T 01-11-2018 IPR020902 Actin/actin-like conserved site TOT_020001102 7788083c0973a4d09150d950c60f53bb 376 Gene3D G3DSA:3.30.420.40 139 339 3.2E-183 T 01-11-2018 TOT_020001102 7788083c0973a4d09150d950c60f53bb 376 SUPERFAMILY SSF53067 148 376 2.51E-95 T 01-11-2018 TOT_020001102 7788083c0973a4d09150d950c60f53bb 376 ProSitePatterns PS00406 Actins signature 1. 54 64 - T 01-11-2018 IPR004001 Actin, conserved site TOT_020001102 7788083c0973a4d09150d950c60f53bb 376 Gene3D G3DSA:3.30.420.40 9 372 3.2E-183 T 01-11-2018 TOT_020001102 7788083c0973a4d09150d950c60f53bb 376 SUPERFAMILY SSF53067 5 154 8.64E-65 T 01-11-2018 TOT_020001102 7788083c0973a4d09150d950c60f53bb 376 Gene3D G3DSA:3.90.640.10 181 273 3.2E-183 T 01-11-2018 TOT_020001102 7788083c0973a4d09150d950c60f53bb 376 PRINTS PR00190 Actin signature 116 129 7.5E-53 T 01-11-2018 IPR004000 Actin family TOT_020001102 7788083c0973a4d09150d950c60f53bb 376 PRINTS PR00190 Actin signature 237 253 7.5E-53 T 01-11-2018 IPR004000 Actin family TOT_020001102 7788083c0973a4d09150d950c60f53bb 376 PRINTS PR00190 Actin signature 50 61 7.5E-53 T 01-11-2018 IPR004000 Actin family TOT_020001102 7788083c0973a4d09150d950c60f53bb 376 PRINTS PR00190 Actin signature 62 84 7.5E-53 T 01-11-2018 IPR004000 Actin family TOT_020001102 7788083c0973a4d09150d950c60f53bb 376 PRINTS PR00190 Actin signature 141 160 7.5E-53 T 01-11-2018 IPR004000 Actin family TOT_020001102 7788083c0973a4d09150d950c60f53bb 376 PRINTS PR00190 Actin signature 27 36 7.5E-53 T 01-11-2018 IPR004000 Actin family TOT_030000654 379c4398a82280a68348984ee3b30b4b 703 Pfam PF04385 Domain of unknown function, DUF529 428 500 2.7E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000392 a8276521a156370d6032e61e41a2c382 363 Gene3D G3DSA:1.10.8.10 287 360 2.6E-9 T 01-11-2018 TOT_020000392 a8276521a156370d6032e61e41a2c382 363 SUPERFAMILY SSF46934 314 355 8.27E-7 T 01-11-2018 IPR009060 UBA-like superfamily GO:0005515 TOT_030000867 14dc2d6f29a8e4879ceb845a284029f2 166 SUPERFAMILY SSF64263 51 165 2.88E-28 T 01-11-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TOT_030000867 14dc2d6f29a8e4879ceb845a284029f2 166 Pfam PF01196 Ribosomal protein L17 66 163 1.0E-21 T 01-11-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TOT_030000867 14dc2d6f29a8e4879ceb845a284029f2 166 Gene3D G3DSA:3.90.1030.10 49 165 2.2E-27 T 01-11-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TOT_030000867 14dc2d6f29a8e4879ceb845a284029f2 166 TIGRFAM TIGR00059 L17: ribosomal protein bL17 54 164 1.3E-25 T 01-11-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TOT_030000487 6ad41a7991fe77ef862d8af0fb67c570 212 SUPERFAMILY SSF69765 50 210 6.93E-47 T 01-11-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TOT_030000487 6ad41a7991fe77ef862d8af0fb67c570 212 Gene3D G3DSA:3.30.1330.50 49 212 2.0E-53 T 01-11-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TOT_030000487 6ad41a7991fe77ef862d8af0fb67c570 212 Pfam PF02542 YgbB family 52 208 8.9E-50 T 01-11-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TOT_030000487 6ad41a7991fe77ef862d8af0fb67c570 212 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 52 208 2.4E-48 T 01-11-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TOT_030000487 6ad41a7991fe77ef862d8af0fb67c570 212 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 51 210 30.123 T 01-11-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TOT_030000487 6ad41a7991fe77ef862d8af0fb67c570 212 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 90 105 - T 01-11-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TOT_020000880 1e07e26fa11e53203943e37ec5cbdf82 222 Pfam PF06644 ATP11 protein 141 206 4.4E-5 T 01-11-2018 IPR010591 ATP11 GO:0005739|GO:0065003 TOT_020000880 1e07e26fa11e53203943e37ec5cbdf82 222 Pfam PF06644 ATP11 protein 13 106 2.4E-10 T 01-11-2018 IPR010591 ATP11 GO:0005739|GO:0065003 TOT_020000936 60df4c566e9841a0efd0e1d23bc574ff 285 SUPERFAMILY SSF89550 88 238 1.1E-19 T 01-11-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TOT_020000936 60df4c566e9841a0efd0e1d23bc574ff 285 Gene3D G3DSA:3.20.20.140 66 260 1.9E-12 T 01-11-2018 TOT_020000936 60df4c566e9841a0efd0e1d23bc574ff 285 Pfam PF01876 RNase P subunit p30 67 225 1.5E-15 T 01-11-2018 IPR002738 RNase P subunit p30 GO:0004540|GO:0008033 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TOT_010000422 00b3899dbb5fa13cd32698341c3e0598 985 SUPERFAMILY SSF103473 140 471 1.7E-6 T 01-11-2018 IPR036259 MFS transporter superfamily TOT_030000359 624bf5bf8b78bdcb986208548fc20312 1649 Gene3D G3DSA:3.90.70.10 193 292 5.6E-11 T 01-11-2018 TOT_030000359 624bf5bf8b78bdcb986208548fc20312 1649 Gene3D G3DSA:3.90.70.10 302 604 9.1E-63 T 01-11-2018 TOT_030000359 624bf5bf8b78bdcb986208548fc20312 1649 ProSitePatterns PS00972 Ubiquitin specific protease (USP) domain signature 1. 197 212 - T 01-11-2018 IPR018200 Ubiquitin specific protease, conserved site GO:0006511|GO:0036459 TOT_030000359 624bf5bf8b78bdcb986208548fc20312 1649 SUPERFAMILY SSF49599 53 175 1.57E-7 T 01-11-2018 IPR008974 TRAF-like GO:0005515 TOT_030000359 624bf5bf8b78bdcb986208548fc20312 1649 SUPERFAMILY SSF54001 192 651 3.92E-84 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily TOT_030000359 624bf5bf8b78bdcb986208548fc20312 1649 Pfam PF00443 Ubiquitin carboxyl-terminal hydrolase 196 627 1.1E-43 T 01-11-2018 IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase GO:0016579|GO:0036459 TOT_030000359 624bf5bf8b78bdcb986208548fc20312 1649 ProSitePatterns PS00973 Ubiquitin specific protease (USP) domain signature 2. 539 556 - T 01-11-2018 IPR018200 Ubiquitin specific protease, conserved site GO:0006511|GO:0036459 TOT_030000359 624bf5bf8b78bdcb986208548fc20312 1649 Gene3D G3DSA:2.60.210.10 41 192 2.1E-17 T 01-11-2018 IPR008974 TRAF-like GO:0005515 TOT_010000641 8c1243f76e7ed80abddf1fc555adcee7 653 Pfam PF03085 Rhoptry-associated protein 1 (RAP-1) 61 184 3.7E-25 T 01-11-2018 IPR004318 Rhoptry-associated protein 1 TOT_010000641 8c1243f76e7ed80abddf1fc555adcee7 653 Pfam PF03085 Rhoptry-associated protein 1 (RAP-1) 255 360 1.3E-18 T 01-11-2018 IPR004318 Rhoptry-associated protein 1 TOT_010000641 8c1243f76e7ed80abddf1fc555adcee7 653 Pfam PF03085 Rhoptry-associated protein 1 (RAP-1) 365 575 9.2E-24 T 01-11-2018 IPR004318 Rhoptry-associated protein 1 TOT_010001158 483b9803184c3468ce27d03b3aa6d22f 168 Pfam PF04385 Domain of unknown function, DUF529 24 94 5.1E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000188 be06a7c3d434cd09ca1857af6ae78f3f 955 Gene3D G3DSA:1.25.40.570 766 898 1.1E-5 T 01-11-2018 TOT_040000188 be06a7c3d434cd09ca1857af6ae78f3f 955 SUPERFAMILY SSF46785 802 872 6.49E-8 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily TOT_040000188 be06a7c3d434cd09ca1857af6ae78f3f 955 Pfam PF05470 Eukaryotic translation initiation factor 3 subunit 8 N-terminus 40 725 1.9E-97 T 01-11-2018 IPR008905 Eukaryotic translation initiation factor 3 subunit C, N-terminal domain GO:0003743|GO:0005852|GO:0006413|GO:0031369 TOT_040000188 be06a7c3d434cd09ca1857af6ae78f3f 955 SMART SM00753 motif in proteasome subunits, Int-6, Nip-1 and TRIP-15 801 889 8.0E-6 T 01-11-2018 TOT_040000188 be06a7c3d434cd09ca1857af6ae78f3f 955 SMART SM00088 801 889 8.0E-6 T 01-11-2018 IPR000717 Proteasome component (PCI) domain TOT_040000188 be06a7c3d434cd09ca1857af6ae78f3f 955 Pfam PF01399 PCI domain 769 868 1.8E-9 T 01-11-2018 IPR000717 Proteasome component (PCI) domain TOT_040000188 be06a7c3d434cd09ca1857af6ae78f3f 955 Hamap MF_03002 Eukaryotic translation initiation factor 3 subunit C [EIF3C]. 3 948 43.442 T 01-11-2018 IPR027516 Eukaryotic translation initiation factor 3 subunit C GO:0003723|GO:0003743|GO:0005852|GO:0006413|GO:0031369 TOT_020000272 8fc96cd89979699ddd75f2f011a519e5 486 SUPERFAMILY SSF103473 99 480 1.1E-18 T 01-11-2018 IPR036259 MFS transporter superfamily TOT_020000272 8fc96cd89979699ddd75f2f011a519e5 486 Pfam PF07690 Major Facilitator Superfamily 107 438 7.8E-9 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOT_020000272 8fc96cd89979699ddd75f2f011a519e5 486 Gene3D G3DSA:1.20.1250.20 35 476 4.1E-19 T 01-11-2018 TOT_040000976 b9d8408e61895f5cb03c5f1642e52690 66 Pfam PF00462 Glutaredoxin 2 47 4.4E-9 T 01-11-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 TOT_040000976 b9d8408e61895f5cb03c5f1642e52690 66 Gene3D G3DSA:3.40.30.10 1 66 6.3E-19 T 01-11-2018 TOT_040000976 b9d8408e61895f5cb03c5f1642e52690 66 SUPERFAMILY SSF52833 2 66 2.24E-17 T 01-11-2018 IPR036249 Thioredoxin-like superfamily TOT_010000243 bfda066d4e954f82e6cdbb6c9b979c16 2959 Gene3D G3DSA:2.60.210.10 67 213 4.5E-16 T 01-11-2018 IPR008974 TRAF-like GO:0005515 TOT_010000243 bfda066d4e954f82e6cdbb6c9b979c16 2959 SUPERFAMILY SSF49599 72 196 3.27E-11 T 01-11-2018 IPR008974 TRAF-like GO:0005515 TOT_020000856 72df6a160d0e8d5acd5a851b68d3074b 835 Pfam PF04385 Domain of unknown function, DUF529 260 308 6.8E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000762 b35bdbbaaf6a4bd36576c14cc1cd6e27 107 SUPERFAMILY SSF55159 18 106 1.44E-30 T 01-11-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 TOT_040000762 b35bdbbaaf6a4bd36576c14cc1cd6e27 107 Pfam PF01253 Translation initiation factor SUI1 23 94 1.4E-23 T 01-11-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 TOT_040000762 b35bdbbaaf6a4bd36576c14cc1cd6e27 107 PIRSF PIRSF004499 2 107 3.8E-44 T 01-11-2018 IPR005874 Eukaryotic translation initiation factor SUI1 GO:0003743 TOT_040000762 b35bdbbaaf6a4bd36576c14cc1cd6e27 107 Gene3D G3DSA:3.30.780.10 6 107 1.4E-35 T 01-11-2018 TOT_010001128 03d4494cadeeb6a430a083197a3ee3da 778 SMART SM00233 484 597 6.9E-5 T 01-11-2018 IPR001849 Pleckstrin homology domain TOT_010001128 03d4494cadeeb6a430a083197a3ee3da 778 SUPERFAMILY SSF50729 487 599 1.17E-7 T 01-11-2018 TOT_010001128 03d4494cadeeb6a430a083197a3ee3da 778 Pfam PF00643 B-box zinc finger 219 263 6.0E-6 T 01-11-2018 IPR000315 B-box-type zinc finger GO:0005622|GO:0008270 TOT_010001128 03d4494cadeeb6a430a083197a3ee3da 778 SUPERFAMILY SSF57845 216 280 4.35E-8 T 01-11-2018 TOT_010001128 03d4494cadeeb6a430a083197a3ee3da 778 Gene3D G3DSA:3.30.40.200 143 264 1.2E-7 T 01-11-2018 TOT_030000593 05a1250464a00eea57a8d6d314aefbb1 741 Pfam PF00270 DEAD/DEAH box helicase 125 290 5.2E-14 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TOT_030000593 05a1250464a00eea57a8d6d314aefbb1 741 SUPERFAMILY SSF52540 134 555 3.84E-23 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_030000593 05a1250464a00eea57a8d6d314aefbb1 741 SMART SM00487 118 329 1.0E-8 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOT_030000593 05a1250464a00eea57a8d6d314aefbb1 741 Gene3D G3DSA:3.40.50.300 446 566 2.7E-11 T 01-11-2018 TOT_030000593 05a1250464a00eea57a8d6d314aefbb1 741 Gene3D G3DSA:3.40.50.300 111 318 1.0E-20 T 01-11-2018 TOT_030000593 05a1250464a00eea57a8d6d314aefbb1 741 Pfam PF00271 Helicase conserved C-terminal domain 454 558 3.6E-6 T 01-11-2018 IPR001650 Helicase, C-terminal TOT_040000060 d588844907015fb2ba3899c780954240 691 Gene3D G3DSA:1.10.510.10 284 505 6.8E-73 T 01-11-2018 TOT_040000060 d588844907015fb2ba3899c780954240 691 Gene3D G3DSA:1.10.510.10 592 691 5.7E-8 T 01-11-2018 TOT_040000060 d588844907015fb2ba3899c780954240 691 SMART SM00220 232 683 1.3E-58 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOT_040000060 d588844907015fb2ba3899c780954240 691 Gene3D G3DSA:3.30.200.20 225 311 6.8E-73 T 01-11-2018 TOT_040000060 d588844907015fb2ba3899c780954240 691 SUPERFAMILY SSF56112 221 685 1.08E-69 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily TOT_040000060 d588844907015fb2ba3899c780954240 691 Pfam PF00069 Protein kinase domain 232 478 6.5E-40 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOT_010001273 5259ae0ef11b835d01bcec19a397ef1c 469 PRINTS PR00171 Sugar transporter signature 373 394 7.5E-11 T 01-11-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TOT_010001273 5259ae0ef11b835d01bcec19a397ef1c 469 PRINTS PR00171 Sugar transporter signature 284 294 7.5E-11 T 01-11-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TOT_010001273 5259ae0ef11b835d01bcec19a397ef1c 469 PRINTS PR00171 Sugar transporter signature 114 133 7.5E-11 T 01-11-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TOT_010001273 5259ae0ef11b835d01bcec19a397ef1c 469 PRINTS PR00171 Sugar transporter signature 396 408 7.5E-11 T 01-11-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TOT_010001273 5259ae0ef11b835d01bcec19a397ef1c 469 Gene3D G3DSA:1.20.1250.20 2 467 6.8E-87 T 01-11-2018 TOT_010001273 5259ae0ef11b835d01bcec19a397ef1c 469 Pfam PF00083 Sugar (and other) transporter 52 464 3.4E-71 T 01-11-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 TOT_010001273 5259ae0ef11b835d01bcec19a397ef1c 469 SUPERFAMILY SSF103473 52 464 2.22E-41 T 01-11-2018 IPR036259 MFS transporter superfamily TOT_010001073 643c580afc8f3dc17ae99109253ea169 725 Pfam PF13091 PLD-like domain 29 168 1.0E-6 T 01-11-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 TOT_010001073 643c580afc8f3dc17ae99109253ea169 725 Gene3D G3DSA:3.30.870.10 477 724 7.3E-34 T 01-11-2018 TOT_010001073 643c580afc8f3dc17ae99109253ea169 725 Gene3D G3DSA:3.30.870.10 14 197 1.6E-48 T 01-11-2018 TOT_010001073 643c580afc8f3dc17ae99109253ea169 725 SUPERFAMILY SSF56024 10 169 1.92E-19 T 01-11-2018 TOT_040000855 b38f2aaf11e552c74df77f2a3d6a2752 453 Pfam PF04385 Domain of unknown function, DUF529 77 141 1.4E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000855 b38f2aaf11e552c74df77f2a3d6a2752 453 Pfam PF04385 Domain of unknown function, DUF529 314 377 3.3E-9 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000573 f50d2e154b293ee4b356e6ef74439976 259 SUPERFAMILY SSF57667 105 144 1.27E-7 T 01-11-2018 IPR036236 Zinc finger C2H2 superfamily TOT_040000573 f50d2e154b293ee4b356e6ef74439976 259 Pfam PF12171 Zinc-finger double-stranded RNA-binding 110 134 1.7E-5 T 01-11-2018 IPR022755 Zinc finger, double-stranded RNA binding TOT_040000573 f50d2e154b293ee4b356e6ef74439976 259 Gene3D G3DSA:3.30.160.60 103 142 1.5E-5 T 01-11-2018 TOT_040000573 f50d2e154b293ee4b356e6ef74439976 259 SMART SM00451 107 141 8.1E-9 T 01-11-2018 IPR003604 Matrin/U1-C-like, C2H2-type zinc finger GO:0003676|GO:0008270 TOT_010001085 f582eb9ef4391ef600f6f8e57e8f8a0c 97 Gene3D G3DSA:3.30.70.100 1 97 3.8E-28 T 01-11-2018 TOT_010001085 f582eb9ef4391ef600f6f8e57e8f8a0c 97 Pfam PF00708 Acylphosphatase 8 95 1.4E-22 T 01-11-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TOT_010001085 f582eb9ef4391ef600f6f8e57e8f8a0c 97 SUPERFAMILY SSF54975 3 95 2.4E-21 T 01-11-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TOT_010001085 f582eb9ef4391ef600f6f8e57e8f8a0c 97 ProSitePatterns PS00150 Acylphosphatase signature 1. 11 21 - T 01-11-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TOT_010001085 f582eb9ef4391ef600f6f8e57e8f8a0c 97 PRINTS PR00112 Acylphosphatase signature 6 21 9.4E-7 T 01-11-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TOT_010001085 f582eb9ef4391ef600f6f8e57e8f8a0c 97 PRINTS PR00112 Acylphosphatase signature 27 52 9.4E-7 T 01-11-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TOT_020000366 a0f745e819500eee1c749ec1b4f719d6 133 Pfam PF05348 Proteasome maturation factor UMP1 31 131 6.3E-16 T 01-11-2018 TOT_010000063 3e5b57be8314c063b20d70417b1c2bd6 782 Pfam PF00847 AP2 domain 354 405 5.4E-15 T 01-11-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 TOT_010000670 0486296d04eaf9fa6843188227bb58d2 438 Pfam PF00549 CoA-ligase 313 430 1.2E-17 T 01-11-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TOT_010000670 0486296d04eaf9fa6843188227bb58d2 438 Pfam PF08442 ATP-grasp domain 45 254 5.9E-54 T 01-11-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TOT_010000670 0486296d04eaf9fa6843188227bb58d2 438 Gene3D G3DSA:3.30.1490.20 64 163 5.7E-74 T 01-11-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TOT_010000670 0486296d04eaf9fa6843188227bb58d2 438 SUPERFAMILY SSF52210 293 436 3.01E-44 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TOT_010000670 0486296d04eaf9fa6843188227bb58d2 438 PIRSF PIRSF001554 44 438 3.3E-128 T 01-11-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TOT_010000670 0486296d04eaf9fa6843188227bb58d2 438 Gene3D G3DSA:3.40.50.261 291 438 7.7E-49 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TOT_010000670 0486296d04eaf9fa6843188227bb58d2 438 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 308 332 - T 01-11-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TOT_010000670 0486296d04eaf9fa6843188227bb58d2 438 Gene3D G3DSA:3.30.470.20 44 283 5.7E-74 T 01-11-2018 TOT_010000670 0486296d04eaf9fa6843188227bb58d2 438 SUPERFAMILY SSF56059 44 283 4.18E-55 T 01-11-2018 TOT_040000799 176af2d731526edd1cae5acf9dd487f8 1730 Pfam PF04385 Domain of unknown function, DUF529 1136 1203 2.9E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000799 176af2d731526edd1cae5acf9dd487f8 1730 Pfam PF04385 Domain of unknown function, DUF529 1454 1528 5.3E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000008 56982a5761e7687bbff14da8f771d489 1507 SUPERFAMILY SSF52540 511 692 4.26E-21 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_040000008 56982a5761e7687bbff14da8f771d489 1507 SMART SM00382 527 727 3.7 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_040000008 56982a5761e7687bbff14da8f771d489 1507 SMART SM00382 1247 1470 0.29 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_040000008 56982a5761e7687bbff14da8f771d489 1507 Gene3D G3DSA:1.20.1560.10 806 1141 9.1E-12 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_040000008 56982a5761e7687bbff14da8f771d489 1507 ProSitePatterns PS00211 ABC transporters family signature. 630 644 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_040000008 56982a5761e7687bbff14da8f771d489 1507 Gene3D G3DSA:3.40.50.300 476 759 9.5E-33 T 01-11-2018 TOT_040000008 56982a5761e7687bbff14da8f771d489 1507 SUPERFAMILY SSF52540 1196 1496 1.7E-24 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_040000008 56982a5761e7687bbff14da8f771d489 1507 Gene3D G3DSA:3.40.50.300 1208 1503 9.6E-40 T 01-11-2018 TOT_040000008 56982a5761e7687bbff14da8f771d489 1507 SUPERFAMILY SSF90123 817 1140 4.45E-25 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_040000008 56982a5761e7687bbff14da8f771d489 1507 Pfam PF00005 ABC transporter 518 645 1.7E-10 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_040000008 56982a5761e7687bbff14da8f771d489 1507 Pfam PF00005 ABC transporter 1238 1425 7.4E-17 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000763 794048936b1551df3be3388fba77d207 661 Gene3D G3DSA:4.10.1000.10 237 301 8.2E-6 T 01-11-2018 TOT_020000763 794048936b1551df3be3388fba77d207 661 SMART SM00356 268 291 1.4 T 01-11-2018 IPR000571 Zinc finger, CCCH-type GO:0046872 TOT_020000763 794048936b1551df3be3388fba77d207 661 SMART SM00356 225 259 2.4 T 01-11-2018 IPR000571 Zinc finger, CCCH-type GO:0046872 TOT_020000763 794048936b1551df3be3388fba77d207 661 SMART SM00356 186 212 0.76 T 01-11-2018 IPR000571 Zinc finger, CCCH-type GO:0046872 TOT_030000242 3db250cb67dd808d40fde45f8ca9751b 400 Gene3D G3DSA:3.20.20.105 178 400 3.4E-25 T 01-11-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TOT_030000242 3db250cb67dd808d40fde45f8ca9751b 400 Pfam PF01702 Queuine tRNA-ribosyltransferase 178 392 2.2E-25 T 01-11-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TOT_030000242 3db250cb67dd808d40fde45f8ca9751b 400 SUPERFAMILY SSF51713 11 396 4.19E-38 T 01-11-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TOT_040000409 0de2f3d59eb4b5b39a03c17d1f042d9d 1804 SMART SM00717 1747 1797 2.7E-5 T 01-11-2018 IPR001005 SANT/Myb domain TOT_040000409 0de2f3d59eb4b5b39a03c17d1f042d9d 1804 SMART SM00717 1421 1469 0.0017 T 01-11-2018 IPR001005 SANT/Myb domain TOT_040000409 0de2f3d59eb4b5b39a03c17d1f042d9d 1804 Gene3D G3DSA:1.20.58.1880 1713 1803 7.1E-11 T 01-11-2018 TOT_040000409 0de2f3d59eb4b5b39a03c17d1f042d9d 1804 SUPERFAMILY SSF46689 1424 1474 4.57E-11 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TOT_040000409 0de2f3d59eb4b5b39a03c17d1f042d9d 1804 Gene3D G3DSA:1.10.10.60 1401 1473 1.5E-16 T 01-11-2018 TOT_040000409 0de2f3d59eb4b5b39a03c17d1f042d9d 1804 SUPERFAMILY SSF46689 1744 1794 1.05E-6 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TOT_010000609 d327d3c5a19ef6395a82c77771508955 1120 Gene3D G3DSA:3.40.50.300 42 441 8.2E-28 T 01-11-2018 TOT_010000609 d327d3c5a19ef6395a82c77771508955 1120 SUPERFAMILY SSF52540 52 272 1.94E-17 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010000609 d327d3c5a19ef6395a82c77771508955 1120 Pfam PF00350 Dynamin family 59 233 8.8E-12 T 01-11-2018 IPR022812 Dynamin superfamily TOT_020000038 bdc4f3a50de8c86035d4936b11af8167 372 TIGRFAM TIGR00321 dhys: deoxyhypusine synthase 34 364 2.1E-106 T 01-11-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 TOT_020000038 bdc4f3a50de8c86035d4936b11af8167 372 Gene3D G3DSA:3.40.910.10 32 372 8.5E-149 T 01-11-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 TOT_020000038 bdc4f3a50de8c86035d4936b11af8167 372 SUPERFAMILY SSF52467 13 370 1.21E-134 T 01-11-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TOT_020000038 bdc4f3a50de8c86035d4936b11af8167 372 Pfam PF01916 Deoxyhypusine synthase 48 361 6.5E-128 T 01-11-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 TOT_040000634 caf5f3c1f8defe19308c0e572f7b3588 135 SUPERFAMILY SSF54189 8 103 3.45E-31 T 01-11-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOT_040000634 caf5f3c1f8defe19308c0e572f7b3588 135 ProSitePatterns PS00529 Ribosomal protein S24e signature. 67 89 - T 01-11-2018 IPR018098 Ribosomal S24e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_040000634 caf5f3c1f8defe19308c0e572f7b3588 135 Gene3D G3DSA:3.30.70.3370 3 135 2.2E-52 T 01-11-2018 TOT_040000634 caf5f3c1f8defe19308c0e572f7b3588 135 ProDom PD006052 RIBOSOMAL S24 40S RIBONUCLEOPROTEIN S24E 30S S24 CDNA RIKEN ACETYLATION 15 87 2.0E-33 T 01-11-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_040000634 caf5f3c1f8defe19308c0e572f7b3588 135 Pfam PF01282 Ribosomal protein S24e 27 104 2.4E-31 T 01-11-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_040000634 caf5f3c1f8defe19308c0e572f7b3588 135 Hamap MF_00545 30S ribosomal protein S24e [rps24e]. 5 108 17.443 T 01-11-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_010000772 4f223a90a8455fc1d7fa66bdfff6171a 514 Pfam PF01925 Sulfite exporter TauE/SafE 400 503 6.7E-10 T 01-11-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TOT_030000328 18278c6ff57298360fd27bd82d44e9e2 350 Pfam PF03151 Triose-phosphate Transporter family 49 347 2.6E-80 T 01-11-2018 IPR004853 Sugar phosphate transporter domain TOT_010000039 15c1b17e7a00114817ecb1b04f59121e 486 SUPERFAMILY SSF53067 31 252 1.58E-46 T 01-11-2018 TOT_010000039 15c1b17e7a00114817ecb1b04f59121e 486 Gene3D G3DSA:3.30.420.40 83 480 7.4E-104 T 01-11-2018 TOT_010000039 15c1b17e7a00114817ecb1b04f59121e 486 SUPERFAMILY SSF53067 259 484 3.02E-53 T 01-11-2018 TOT_010000039 15c1b17e7a00114817ecb1b04f59121e 486 Pfam PF00349 Hexokinase 32 250 8.5E-47 T 01-11-2018 IPR022672 Hexokinase, N-terminal GO:0005524|GO:0005975|GO:0016773 KEGG: 00010+2.7.1.1|KEGG: 00051+2.7.1.1|KEGG: 00052+2.7.1.1|KEGG: 00500+2.7.1.1|KEGG: 00520+2.7.1.1|KEGG: 00521+2.7.1.1|KEGG: 00524+2.7.1.1|Reactome: R-HSA-70171 TOT_010000039 15c1b17e7a00114817ecb1b04f59121e 486 Gene3D G3DSA:3.40.367.20 74 469 7.4E-104 T 01-11-2018 TOT_010000039 15c1b17e7a00114817ecb1b04f59121e 486 PRINTS PR00475 Hexokinase family signature 98 114 2.4E-51 T 01-11-2018 TOT_010000039 15c1b17e7a00114817ecb1b04f59121e 486 PRINTS PR00475 Hexokinase family signature 177 202 2.4E-51 T 01-11-2018 TOT_010000039 15c1b17e7a00114817ecb1b04f59121e 486 PRINTS PR00475 Hexokinase family signature 234 250 2.4E-51 T 01-11-2018 TOT_010000039 15c1b17e7a00114817ecb1b04f59121e 486 PRINTS PR00475 Hexokinase family signature 261 275 2.4E-51 T 01-11-2018 TOT_010000039 15c1b17e7a00114817ecb1b04f59121e 486 PRINTS PR00475 Hexokinase family signature 394 416 2.4E-51 T 01-11-2018 TOT_010000039 15c1b17e7a00114817ecb1b04f59121e 486 PRINTS PR00475 Hexokinase family signature 466 482 2.4E-51 T 01-11-2018 TOT_010000039 15c1b17e7a00114817ecb1b04f59121e 486 PRINTS PR00475 Hexokinase family signature 318 340 2.4E-51 T 01-11-2018 TOT_010000039 15c1b17e7a00114817ecb1b04f59121e 486 Pfam PF03727 Hexokinase 260 482 2.7E-47 T 01-11-2018 IPR022673 Hexokinase, C-terminal GO:0005524|GO:0005975|GO:0016773 KEGG: 00010+2.7.1.1|KEGG: 00051+2.7.1.1|KEGG: 00052+2.7.1.1|KEGG: 00500+2.7.1.1|KEGG: 00520+2.7.1.1|KEGG: 00521+2.7.1.1|KEGG: 00524+2.7.1.1|Reactome: R-HSA-70171 TOT_040000300 3d3200c54ba3c1ef14749a166801d696 390 Pfam PF14360 PAP2 superfamily C-terminal 198 266 1.3E-10 T 01-11-2018 IPR025749 Sphingomyelin synthase-like domain Reactome: R-HSA-1660661 TOT_010000188 cf1e42c0a39634176c60a85b4365fca5 147 Gene3D G3DSA:3.30.230.10 3 147 1.8E-59 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TOT_010000188 cf1e42c0a39634176c60a85b4365fca5 147 Pfam PF00380 Ribosomal protein S9/S16 15 147 2.0E-29 T 01-11-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 TOT_010000188 cf1e42c0a39634176c60a85b4365fca5 147 SUPERFAMILY SSF54211 10 147 2.2E-35 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TOT_010000188 cf1e42c0a39634176c60a85b4365fca5 147 ProSitePatterns PS00360 Ribosomal protein S9 signature. 75 93 - T 01-11-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 TOT_030000641 7e216f7be59b699ef0f4964354a91574 359 Pfam PF04502 Family of unknown function (DUF572) 11 344 9.2E-34 T 01-11-2018 IPR007590 CWC16 protein TOT_030000208 724c5ab6eabfa0f3194ea589d762996a 519 Gene3D G3DSA:3.40.50.150 92 327 1.3E-7 T 01-11-2018 TOT_020001029 c2958488ce61dda1f72da13ebc123cbd 961 SUPERFAMILY SSF55277 448 514 1.07E-17 T 01-11-2018 IPR035445 GYF-like domain superfamily TOT_020001029 c2958488ce61dda1f72da13ebc123cbd 961 Gene3D G3DSA:3.30.1490.40 452 530 1.5E-14 T 01-11-2018 IPR035445 GYF-like domain superfamily TOT_020001029 c2958488ce61dda1f72da13ebc123cbd 961 SMART SM00444 463 521 4.5E-7 T 01-11-2018 IPR003169 GYF domain GO:0005515 TOT_020001029 c2958488ce61dda1f72da13ebc123cbd 961 Pfam PF02213 GYF domain 464 503 3.9E-11 T 01-11-2018 IPR003169 GYF domain GO:0005515 TOT_020000821 20d6e38a0215fe6c01dd7b42e673edd5 3236 Pfam PF04385 Domain of unknown function, DUF529 244 312 3.4E-7 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000579 efeae79bdc777edb7c4cf49470cf677f 446 Pfam PF07534 TLD 309 442 1.2E-32 T 01-11-2018 IPR006571 TLDc domain TOT_020000579 efeae79bdc777edb7c4cf49470cf677f 446 SMART SM00584 282 442 2.1E-31 T 01-11-2018 IPR006571 TLDc domain TOT_030000357 9b4ddfebc895ee95aab20742ca9627a1 368 Pfam PF01189 16S rRNA methyltransferase RsmB/F 112 364 2.7E-23 T 01-11-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TOT_030000357 9b4ddfebc895ee95aab20742ca9627a1 368 SUPERFAMILY SSF53335 72 366 1.34E-28 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOT_030000357 9b4ddfebc895ee95aab20742ca9627a1 368 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 349 366 1.7E-15 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase TOT_030000357 9b4ddfebc895ee95aab20742ca9627a1 368 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 257 273 1.7E-15 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase TOT_030000357 9b4ddfebc895ee95aab20742ca9627a1 368 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 118 128 1.7E-15 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase TOT_030000357 9b4ddfebc895ee95aab20742ca9627a1 368 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 198 210 1.7E-15 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase TOT_010000699 3d10c989b86d5b7db03515c5554506d4 988 Gene3D G3DSA:2.60.40.10 27 163 6.8E-7 T 01-11-2018 IPR013783 Immunoglobulin-like fold TOT_010000699 3d10c989b86d5b7db03515c5554506d4 988 Pfam PF00630 Filamin/ABP280 repeat 30 154 4.5E-9 T 01-11-2018 IPR017868 Filamin/ABP280 repeat-like TOT_010000699 3d10c989b86d5b7db03515c5554506d4 988 SUPERFAMILY SSF81296 28 160 9.75E-9 T 01-11-2018 IPR014756 Immunoglobulin E-set TOT_010000086 fb18624ce180db07c5962521ac115eb6 152 Pfam PF04384 Iron-sulphur cluster assembly 85 149 5.0E-19 T 01-11-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 TOT_010000086 fb18624ce180db07c5962521ac115eb6 152 SUPERFAMILY SSF140319 84 147 4.84E-15 T 01-11-2018 IPR036762 IscX-like superfamily TOT_010000086 fb18624ce180db07c5962521ac115eb6 152 TIGRFAM TIGR03412 iscX_yfhJ: FeS assembly protein IscX 85 147 4.3E-12 T 01-11-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 TOT_010000086 fb18624ce180db07c5962521ac115eb6 152 Gene3D G3DSA:1.10.10.600 75 150 1.2E-11 T 01-11-2018 IPR036762 IscX-like superfamily TOT_010001008 a7ad7f020d6429e4b5c893789cf41050 942 Pfam PF12842 Domain of unknown function (DUF3819) 669 808 1.2E-36 T 01-11-2018 IPR024557 CCR4-Not complex, Not1 subunit, domain of unknown function DUF3819 Reactome: R-HSA-429947|Reactome: R-HSA-6804115 TOT_010001008 a7ad7f020d6429e4b5c893789cf41050 942 Gene3D G3DSA:1.25.40.840 20 186 4.0E-45 T 01-11-2018 IPR038535 CCR4-NOT subunit 1, TTP binding domain superfamily Reactome: R-HSA-429947|Reactome: R-HSA-6804115 TOT_010001008 a7ad7f020d6429e4b5c893789cf41050 942 Gene3D G3DSA:1.25.40.180 227 469 4.5E-77 T 01-11-2018 IPR016021 MIF4G-like domain superfamily TOT_010001008 a7ad7f020d6429e4b5c893789cf41050 942 Pfam PF16415 CCR4-NOT transcription complex subunit 1 CAF1-binding domain 249 464 6.7E-73 T 01-11-2018 IPR032191 CCR4-NOT transcription complex subunit 1, CAF1-binding domain Reactome: R-HSA-429947|Reactome: R-HSA-6804115 TOT_010001008 a7ad7f020d6429e4b5c893789cf41050 942 Pfam PF16417 CCR4-NOT transcription complex subunit 1 TTP binding domain 30 179 1.2E-40 T 01-11-2018 IPR032193 CCR4-NOT transcription complex subunit 1, TTP binding domain Reactome: R-HSA-429947|Reactome: R-HSA-6804115 TOT_010000532 cbc6fce3436e6c099e81fcd0e683e607 819 Gene3D G3DSA:1.10.150.840 289 351 2.3E-5 T 01-11-2018 TOT_020001069 f8f5b46145af101aec16fd866326074d 358 Pfam PF00573 Ribosomal protein L4/L1 family 22 254 3.0E-40 T 01-11-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 TOT_020001069 f8f5b46145af101aec16fd866326074d 358 SUPERFAMILY SSF52166 9 255 2.75E-66 T 01-11-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 TOT_020001069 f8f5b46145af101aec16fd866326074d 358 Gene3D G3DSA:3.40.1370.10 1 290 1.9E-101 T 01-11-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 TOT_040000809 b01e18d47a226d820aa7b230c324675b 279 Pfam PF04385 Domain of unknown function, DUF529 164 204 4.0E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_030000873 8f7487bb081f9d0484a53172890466e8 165 Pfam PF04385 Domain of unknown function, DUF529 45 105 1.7E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000272 2f1801b8c393af568fc72acf4ac832d3 313 Gene3D G3DSA:3.30.70.1730 17 209 2.1E-71 T 01-11-2018 TOT_010000272 2f1801b8c393af568fc72acf4ac832d3 313 Pfam PF00466 Ribosomal protein L10 6 105 2.6E-18 T 01-11-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 TOT_010000272 2f1801b8c393af568fc72acf4ac832d3 313 Gene3D G3DSA:3.90.105.20 107 185 2.1E-71 T 01-11-2018 TOT_010000272 2f1801b8c393af568fc72acf4ac832d3 313 PIRSF PIRSF039087 1 313 8.5E-138 T 01-11-2018 IPR030670 60S acidic ribosomal protein P0 GO:0042254 TOT_010000272 2f1801b8c393af568fc72acf4ac832d3 313 SUPERFAMILY SSF160369 7 130 1.02E-18 T 01-11-2018 TOT_010000272 2f1801b8c393af568fc72acf4ac832d3 313 Pfam PF00428 60s Acidic ribosomal protein 231 312 2.5E-14 T 01-11-2018 TOT_020000750 6ba15194e44d3b667bd5c9d378269bf0 266 Pfam PF08698 Fcf2 pre-rRNA processing 128 234 4.8E-18 T 01-11-2018 IPR014810 Fcf2 pre-rRNA processing, C-terminal TOT_020001032 a786079ac7b06955f5a03240c7d34a3e 314 Pfam PF13489 Methyltransferase domain 106 275 1.8E-24 T 01-11-2018 TOT_020001032 a786079ac7b06955f5a03240c7d34a3e 314 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 23 306 31.861 T 01-11-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 TOT_020001032 a786079ac7b06955f5a03240c7d34a3e 314 SUPERFAMILY SSF53335 15 291 1.36E-35 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOT_020001032 a786079ac7b06955f5a03240c7d34a3e 314 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 27 300 5.5E-57 T 01-11-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 TOT_020000643 254eb28b7abe1339acbfcbb155e2e2dc 328 SUPERFAMILY SSF56112 14 327 1.27E-64 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily TOT_020000643 254eb28b7abe1339acbfcbb155e2e2dc 328 Pfam PF01633 Choline/ethanolamine kinase 78 276 2.1E-31 T 01-11-2018 TOT_020000643 254eb28b7abe1339acbfcbb155e2e2dc 328 Gene3D G3DSA:3.30.200.20 22 115 3.8E-77 T 01-11-2018 TOT_020000643 254eb28b7abe1339acbfcbb155e2e2dc 328 Gene3D G3DSA:3.90.1200.10 75 327 3.8E-77 T 01-11-2018 TOT_040000551 e8695056557b6bced74a03494bbbe2b1 564 Gene3D G3DSA:2.130.10.10 2 199 1.6E-15 T 01-11-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TOT_040000551 e8695056557b6bced74a03494bbbe2b1 564 Gene3D G3DSA:2.130.10.10 200 423 6.5E-10 T 01-11-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TOT_040000551 e8695056557b6bced74a03494bbbe2b1 564 Pfam PF00400 WD domain, G-beta repeat 149 182 2.9E-5 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_040000551 e8695056557b6bced74a03494bbbe2b1 564 SUPERFAMILY SSF50998 57 389 2.67E-28 T 01-11-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TOT_040000551 e8695056557b6bced74a03494bbbe2b1 564 SMART SM00320 137 182 6.5E-4 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_040000551 e8695056557b6bced74a03494bbbe2b1 564 SMART SM00320 48 82 28.0 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_040000551 e8695056557b6bced74a03494bbbe2b1 564 SMART SM00320 203 254 110.0 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_040000551 e8695056557b6bced74a03494bbbe2b1 564 SMART SM00320 257 294 320.0 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_010001065 d279723acba92a1a30104856127d11c7 1000 Gene3D G3DSA:1.10.150.780 695 951 4.7E-22 T 01-11-2018 IPR038132 Vps16, C-terminal domain superfamily TOT_010001065 d279723acba92a1a30104856127d11c7 1000 Pfam PF04840 Vps16, C-terminal region 679 942 3.8E-15 T 01-11-2018 IPR006925 Vps16, C-terminal GO:0005737|GO:0006886 TOT_010001065 d279723acba92a1a30104856127d11c7 1000 Pfam PF04841 Vps16, N-terminal region 379 465 2.7E-7 T 01-11-2018 IPR006926 Vps16, N-terminal GO:0005737|GO:0006886 TOT_010000827 1e20b082355732dacfcd01f0cfd1d00d 326 SMART SM00360 148 218 8.9E-13 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_010000827 1e20b082355732dacfcd01f0cfd1d00d 326 SMART SM00360 57 128 2.0E-17 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_010000827 1e20b082355732dacfcd01f0cfd1d00d 326 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 149 205 3.6E-13 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_010000827 1e20b082355732dacfcd01f0cfd1d00d 326 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 58 116 7.5E-14 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_010000827 1e20b082355732dacfcd01f0cfd1d00d 326 Gene3D G3DSA:3.30.70.330 139 233 1.0E-18 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_010000827 1e20b082355732dacfcd01f0cfd1d00d 326 Gene3D G3DSA:3.30.70.330 47 138 7.9E-24 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_010000827 1e20b082355732dacfcd01f0cfd1d00d 326 SUPERFAMILY SSF54928 141 229 3.09E-20 T 01-11-2018 IPR035979 RNA-binding domain superfamily GO:0003676 TOT_010000827 1e20b082355732dacfcd01f0cfd1d00d 326 SUPERFAMILY SSF54928 25 136 6.99E-23 T 01-11-2018 IPR035979 RNA-binding domain superfamily GO:0003676 TOT_010001242 eb17b093a8fba42a9f5122e09a4a15c1 1280 SUPERFAMILY SSF81301 337 513 3.47E-12 T 01-11-2018 TOT_010001242 eb17b093a8fba42a9f5122e09a4a15c1 1280 Gene3D G3DSA:3.30.460.10 355 498 6.4E-11 T 01-11-2018 TOT_040000835 16ddd24856e904eb11bd8fcefb9a167b 1139 Pfam PF04385 Domain of unknown function, DUF529 798 870 6.0E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000835 16ddd24856e904eb11bd8fcefb9a167b 1139 Pfam PF04385 Domain of unknown function, DUF529 613 685 1.0E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000880 d9286917ce6df0b489eb2de24cae6dfb 505 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 429 455 - T 01-11-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 TOT_040000880 d9286917ce6df0b489eb2de24cae6dfb 505 Pfam PF01148 Cytidylyltransferase family 200 471 9.3E-54 T 01-11-2018 TOT_030000535 19890cd35bd8d794624916ca9d382d79 338 SUPERFAMILY SSF56112 11 295 2.02E-85 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily TOT_030000535 19890cd35bd8d794624916ca9d382d79 338 Pfam PF00069 Protein kinase domain 14 232 1.4E-28 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOT_030000535 19890cd35bd8d794624916ca9d382d79 338 SMART SM00220 14 283 5.3E-16 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOT_030000535 19890cd35bd8d794624916ca9d382d79 338 Gene3D G3DSA:1.10.510.10 2 337 3.5E-107 T 01-11-2018 TOT_030000535 19890cd35bd8d794624916ca9d382d79 338 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 01-11-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TOT_030000535 19890cd35bd8d794624916ca9d382d79 338 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 20 43 - T 01-11-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TOT_040000560 3a400d0dc373157d041ae74eb228c0d6 1871 SUPERFAMILY SSF48371 547 1568 1.11E-13 T 01-11-2018 IPR016024 Armadillo-type fold TOT_040000560 3a400d0dc373157d041ae74eb228c0d6 1871 Pfam PF12717 non-SMC mitotic condensation complex subunit 1 1400 1571 1.1E-26 T 01-11-2018 IPR032682 Condensin complex subunit 1, C-terminal TOT_030000847 6a410afde1a527aa9188d4424036f055 1710 Pfam PF04385 Domain of unknown function, DUF529 618 686 2.2E-7 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_030000847 6a410afde1a527aa9188d4424036f055 1710 Pfam PF04385 Domain of unknown function, DUF529 1222 1275 1.9E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000323 0c33278e3361b88dde4073a079a84b6a 917 SUPERFAMILY SSF48403 560 895 9.95E-46 T 01-11-2018 IPR036770 Ankyrin repeat-containing domain superfamily TOT_040000323 0c33278e3361b88dde4073a079a84b6a 917 SMART SM00248 791 820 7.2E-4 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 TOT_040000323 0c33278e3361b88dde4073a079a84b6a 917 SMART SM00248 858 888 39.0 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 TOT_040000323 0c33278e3361b88dde4073a079a84b6a 917 SMART SM00248 658 687 1.2E-4 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 TOT_040000323 0c33278e3361b88dde4073a079a84b6a 917 SMART SM00248 622 651 0.39 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 TOT_040000323 0c33278e3361b88dde4073a079a84b6a 917 SMART SM00248 724 753 1300.0 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 TOT_040000323 0c33278e3361b88dde4073a079a84b6a 917 SMART SM00248 758 787 390.0 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 TOT_040000323 0c33278e3361b88dde4073a079a84b6a 917 SMART SM00248 556 585 800.0 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 TOT_040000323 0c33278e3361b88dde4073a079a84b6a 917 SMART SM00248 824 853 1.4E-4 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 TOT_040000323 0c33278e3361b88dde4073a079a84b6a 917 SMART SM00248 589 619 2600.0 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 TOT_040000323 0c33278e3361b88dde4073a079a84b6a 917 Pfam PF12796 Ankyrin repeats (3 copies) 765 854 1.3E-16 T 01-11-2018 IPR020683 Ankyrin repeat-containing domain TOT_040000323 0c33278e3361b88dde4073a079a84b6a 917 Pfam PF12796 Ankyrin repeats (3 copies) 569 651 3.6E-8 T 01-11-2018 IPR020683 Ankyrin repeat-containing domain TOT_040000323 0c33278e3361b88dde4073a079a84b6a 917 PRINTS PR01415 Ankyrin repeat signature 792 807 2.4E-5 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 TOT_040000323 0c33278e3361b88dde4073a079a84b6a 917 PRINTS PR01415 Ankyrin repeat signature 840 854 2.4E-5 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 TOT_040000323 0c33278e3361b88dde4073a079a84b6a 917 Gene3D G3DSA:3.80.10.10 267 367 2.5E-5 T 01-11-2018 IPR032675 Leucine-rich repeat domain superfamily TOT_010000167 c4d1306fdc980eca71e414ae59ae5145 243 Pfam PF00411 Ribosomal protein S11 136 242 8.4E-5 T 01-11-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TOT_010000167 c4d1306fdc980eca71e414ae59ae5145 243 SUPERFAMILY SSF53137 127 243 4.49E-20 T 01-11-2018 TOT_010000167 c4d1306fdc980eca71e414ae59ae5145 243 Gene3D G3DSA:3.30.420.80 119 243 1.4E-13 T 01-11-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 TOT_040000301 a90fa719b4d07683b27b9a7ca129bbd4 394 Gene3D G3DSA:1.20.144.10 207 305 8.4E-8 T 01-11-2018 TOT_040000301 a90fa719b4d07683b27b9a7ca129bbd4 394 Pfam PF14360 PAP2 superfamily C-terminal 201 271 1.2E-16 T 01-11-2018 IPR025749 Sphingomyelin synthase-like domain Reactome: R-HSA-1660661 TOT_020000074 1a26f13718750df893b2ab06031c8d14 164 SMART SM01407 55 111 3.2E-18 T 01-11-2018 IPR002715 Nascent polypeptide-associated complex NAC domain TOT_020000074 1a26f13718750df893b2ab06031c8d14 164 Pfam PF01849 NAC domain 55 111 7.7E-19 T 01-11-2018 IPR002715 Nascent polypeptide-associated complex NAC domain TOT_020000074 1a26f13718750df893b2ab06031c8d14 164 Gene3D G3DSA:2.20.70.30 68 122 1.8E-20 T 01-11-2018 IPR038187 NAC A/B domain superfamily TOT_040000912 855b18cd8e96c500b08464e032cad11d 520 SMART SM00320 9 47 76.0 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_040000912 855b18cd8e96c500b08464e032cad11d 520 SMART SM00320 359 401 450.0 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_040000912 855b18cd8e96c500b08464e032cad11d 520 SMART SM00320 286 328 13.0 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_040000912 855b18cd8e96c500b08464e032cad11d 520 SMART SM00320 241 278 45.0 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_040000912 855b18cd8e96c500b08464e032cad11d 520 SMART SM00320 107 153 6.5E-4 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_040000912 855b18cd8e96c500b08464e032cad11d 520 SUPERFAMILY SSF50978 19 409 1.41E-24 T 01-11-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 TOT_020000151 450e2e446cbeff37bc6cdbcebc1afaea 780 Pfam PF00847 AP2 domain 264 309 6.2E-5 T 01-11-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 TOT_020000995 96e6681932dfe53356954f8dd663652c 140 SUPERFAMILY SSF52833 24 115 2.62E-25 T 01-11-2018 IPR036249 Thioredoxin-like superfamily TOT_020000995 96e6681932dfe53356954f8dd663652c 140 Gene3D G3DSA:3.40.30.10 17 138 4.4E-26 T 01-11-2018 TOT_020000995 96e6681932dfe53356954f8dd663652c 140 Pfam PF00085 Thioredoxin 29 120 7.5E-21 T 01-11-2018 IPR013766 Thioredoxin domain GO:0045454 TOT_010000920 cb41a502fb1b1a5c6679a7afc9d51435 272 Pfam PF00847 AP2 domain 212 259 2.0E-11 T 01-11-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 TOT_020000045 001ca982b65fc592101f93ec99e6f45d 130 SUPERFAMILY SSF56047 3 130 4.71E-41 T 01-11-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_020000045 001ca982b65fc592101f93ec99e6f45d 130 Gene3D G3DSA:3.30.1370.30 1 69 1.5E-37 T 01-11-2018 TOT_020000045 001ca982b65fc592101f93ec99e6f45d 130 Pfam PF00410 Ribosomal protein S8 7 129 5.7E-20 T 01-11-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_020000045 001ca982b65fc592101f93ec99e6f45d 130 Gene3D G3DSA:3.30.1490.10 70 128 1.3E-29 T 01-11-2018 TOT_040000810 1bdf673211eab865311d066305d247fc 655 Pfam PF04385 Domain of unknown function, DUF529 548 615 6.0E-10 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000810 1bdf673211eab865311d066305d247fc 655 Pfam PF04385 Domain of unknown function, DUF529 448 510 1.7E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000802 ee36d39252e7f77c9091747c77d89fd2 8811 Pfam PF04385 Domain of unknown function, DUF529 409 468 3.9E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_030000008 536f2de7381bb080eaa2829df0f4cb10 844 Pfam PF04385 Domain of unknown function, DUF529 656 713 3.2E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010001339 44659e4c0b6d9664f055afd4f64d157a 362 SUPERFAMILY SSF46689 65 113 1.09E-5 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TOT_010001339 44659e4c0b6d9664f055afd4f64d157a 362 Pfam PF13921 Myb-like DNA-binding domain 67 113 5.4E-6 T 01-11-2018 TOT_010001339 44659e4c0b6d9664f055afd4f64d157a 362 SMART SM00717 63 114 7.4E-4 T 01-11-2018 IPR001005 SANT/Myb domain TOT_010001014 26f9573960637b89f30d4b0f57a2e6ef 370 Gene3D G3DSA:1.20.1250.20 1 366 9.3E-66 T 01-11-2018 TOT_010001014 26f9573960637b89f30d4b0f57a2e6ef 370 SUPERFAMILY SSF103473 3 364 2.88E-31 T 01-11-2018 IPR036259 MFS transporter superfamily TOT_010001014 26f9573960637b89f30d4b0f57a2e6ef 370 PRINTS PR00171 Sugar transporter signature 185 195 3.5E-8 T 01-11-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TOT_010001014 26f9573960637b89f30d4b0f57a2e6ef 370 PRINTS PR00171 Sugar transporter signature 297 309 3.5E-8 T 01-11-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TOT_010001014 26f9573960637b89f30d4b0f57a2e6ef 370 PRINTS PR00171 Sugar transporter signature 10 29 3.5E-8 T 01-11-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TOT_010001014 26f9573960637b89f30d4b0f57a2e6ef 370 PRINTS PR00171 Sugar transporter signature 274 295 3.5E-8 T 01-11-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TOT_010001014 26f9573960637b89f30d4b0f57a2e6ef 370 Pfam PF00083 Sugar (and other) transporter 5 363 5.2E-49 T 01-11-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 TOT_010001281 0e3bc9d0950bfee2e115df2d41095662 800 Pfam PF03085 Rhoptry-associated protein 1 (RAP-1) 556 766 3.2E-25 T 01-11-2018 IPR004318 Rhoptry-associated protein 1 TOT_010001281 0e3bc9d0950bfee2e115df2d41095662 800 Pfam PF03085 Rhoptry-associated protein 1 (RAP-1) 97 322 3.2E-44 T 01-11-2018 IPR004318 Rhoptry-associated protein 1 TOT_010001281 0e3bc9d0950bfee2e115df2d41095662 800 Pfam PF03085 Rhoptry-associated protein 1 (RAP-1) 331 551 1.7E-38 T 01-11-2018 IPR004318 Rhoptry-associated protein 1 TOT_030000778 8617ef83416b5190c422eb6c86a00224 826 Pfam PF03074 Glutamate-cysteine ligase 394 592 9.9E-31 T 01-11-2018 IPR004308 Glutamate-cysteine ligase catalytic subunit GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255|Reactome: R-HSA-174403|Reactome: R-HSA-5578999 TOT_030000778 8617ef83416b5190c422eb6c86a00224 826 Pfam PF03074 Glutamate-cysteine ligase 655 823 1.3E-37 T 01-11-2018 IPR004308 Glutamate-cysteine ligase catalytic subunit GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255|Reactome: R-HSA-174403|Reactome: R-HSA-5578999 TOT_030000778 8617ef83416b5190c422eb6c86a00224 826 SUPERFAMILY SSF55931 42 816 6.28E-26 T 01-11-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TOT_030000778 8617ef83416b5190c422eb6c86a00224 826 Gene3D G3DSA:3.30.590.50 346 476 2.6E-20 T 01-11-2018 TOT_030000778 8617ef83416b5190c422eb6c86a00224 826 Gene3D G3DSA:3.30.590.50 623 712 8.2E-15 T 01-11-2018 TOT_030000778 8617ef83416b5190c422eb6c86a00224 826 Gene3D G3DSA:1.10.8.960 789 825 9.8E-7 T 01-11-2018 TOT_040000437 0bdc85d2c702e8e4743b6c7c897124d9 1273 Gene3D G3DSA:3.40.50.12660 664 867 1.8E-23 T 01-11-2018 TOT_040000437 0bdc85d2c702e8e4743b6c7c897124d9 1273 Gene3D G3DSA:3.40.50.12660 493 618 2.4E-10 T 01-11-2018 TOT_040000437 0bdc85d2c702e8e4743b6c7c897124d9 1273 Pfam PF00656 Caspase domain 555 851 5.1E-24 T 01-11-2018 TOT_020000855 3707869b069af8cf33fa5be44fee9c55 958 Pfam PF04385 Domain of unknown function, DUF529 38 86 1.7E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000764 8b33fbb49ec04574045818b32438a0a1 1293 SMART SM00504 1221 1284 7.5E-18 T 01-11-2018 IPR003613 U box domain GO:0004842|GO:0016567 MetaCyc: PWY-7511 TOT_010000764 8b33fbb49ec04574045818b32438a0a1 1293 Pfam PF10408 Ubiquitin elongating factor core 281 1198 1.3E-129 T 01-11-2018 IPR019474 Ubiquitin conjugation factor E4, core GO:0000151|GO:0006511|GO:0016567|GO:0034450 MetaCyc: PWY-7511 TOT_010000764 8b33fbb49ec04574045818b32438a0a1 1293 Pfam PF04564 U-box domain 1218 1287 6.1E-23 T 01-11-2018 IPR003613 U box domain GO:0004842|GO:0016567 MetaCyc: PWY-7511 TOT_010000764 8b33fbb49ec04574045818b32438a0a1 1293 SUPERFAMILY SSF57850 1213 1287 2.3E-21 T 01-11-2018 TOT_010000764 8b33fbb49ec04574045818b32438a0a1 1293 Gene3D G3DSA:3.30.40.10 1217 1292 6.1E-22 T 01-11-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type TOT_040000145 ad0150b7684e3080de3306f769480284 1620 SUPERFAMILY SSF48452 1150 1212 5.52E-6 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TOT_020000749 0c852eafb19efec7c0659cf604dcf8ea 1466 Gene3D G3DSA:3.40.50.150 583 703 2.4E-12 T 01-11-2018 TOT_020000749 0c852eafb19efec7c0659cf604dcf8ea 1466 SUPERFAMILY SSF53335 620 1035 4.57E-5 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOT_020000749 0c852eafb19efec7c0659cf604dcf8ea 1466 SUPERFAMILY SSF53335 620 685 9.74E-8 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOT_010000648 eebc844b00eea251ba067e6411434bd0 269 Pfam PF04385 Domain of unknown function, DUF529 119 164 5.8E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000524 4060626f33decf305006635627916eb5 215 SUPERFAMILY SSF47473 4 137 5.11E-5 T 01-11-2018 IPR011992 EF-hand domain pair TOT_030000826 b21e551e923b9bf4f7981cf6204edc08 371 Pfam PF00400 WD domain, G-beta repeat 195 234 0.0026 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_030000826 b21e551e923b9bf4f7981cf6204edc08 371 Gene3D G3DSA:2.130.10.10 28 365 6.4E-16 T 01-11-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TOT_030000826 b21e551e923b9bf4f7981cf6204edc08 371 SUPERFAMILY SSF50978 26 308 2.26E-14 T 01-11-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 TOT_030000826 b21e551e923b9bf4f7981cf6204edc08 371 SMART SM00320 252 298 37.0 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_030000826 b21e551e923b9bf4f7981cf6204edc08 371 SMART SM00320 190 235 9.2E-4 T 01-11-2018 IPR001680 WD40 repeat GO:0005515 TOT_030000792 707f28d0429d1076fa0ae9b94a6c8451 202 Gene3D G3DSA:3.10.129.10 47 199 6.9E-19 T 01-11-2018 TOT_030000792 707f28d0429d1076fa0ae9b94a6c8451 202 Pfam PF03061 Thioesterase superfamily 110 157 9.2E-6 T 01-11-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TOT_030000792 707f28d0429d1076fa0ae9b94a6c8451 202 SUPERFAMILY SSF54637 94 191 8.07E-18 T 01-11-2018 IPR029069 HotDog domain superfamily TOT_030000701 7c155227af96b919bd42b9dd41384e99 664 Pfam PF04385 Domain of unknown function, DUF529 61 127 1.7E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000612 68dde4d9a508587b884d76ae0c89d87c 1517 SUPERFAMILY SSF52540 1232 1497 6.56E-24 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010000612 68dde4d9a508587b884d76ae0c89d87c 1517 SUPERFAMILY SSF52540 526 719 1.89E-23 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_010000612 68dde4d9a508587b884d76ae0c89d87c 1517 Gene3D G3DSA:3.40.50.300 496 756 2.9E-34 T 01-11-2018 TOT_010000612 68dde4d9a508587b884d76ae0c89d87c 1517 SUPERFAMILY SSF90123 832 1151 7.06E-21 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_010000612 68dde4d9a508587b884d76ae0c89d87c 1517 SMART SM00382 542 745 0.69 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_010000612 68dde4d9a508587b884d76ae0c89d87c 1517 SMART SM00382 1263 1506 0.47 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_010000612 68dde4d9a508587b884d76ae0c89d87c 1517 ProSitePatterns PS00211 ABC transporters family signature. 645 659 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_010000612 68dde4d9a508587b884d76ae0c89d87c 1517 Gene3D G3DSA:1.20.1560.10 810 1156 1.2E-8 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_010000612 68dde4d9a508587b884d76ae0c89d87c 1517 Pfam PF00005 ABC transporter 533 660 1.1E-12 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_010000612 68dde4d9a508587b884d76ae0c89d87c 1517 Pfam PF00005 ABC transporter 1254 1434 3.0E-17 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_010000612 68dde4d9a508587b884d76ae0c89d87c 1517 Gene3D G3DSA:3.40.50.300 1224 1514 2.2E-40 T 01-11-2018 TOT_020000382 48ead9720a4c760b99e4011b30f1f97a 1550 SUPERFAMILY SSF90123 851 1169 2.49E-21 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000382 48ead9720a4c760b99e4011b30f1f97a 1550 SUPERFAMILY SSF52540 1222 1532 1.82E-26 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000382 48ead9720a4c760b99e4011b30f1f97a 1550 Pfam PF00005 ABC transporter 553 680 1.2E-12 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000382 48ead9720a4c760b99e4011b30f1f97a 1550 ProSitePatterns PS00211 ABC transporters family signature. 665 679 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOT_020000382 48ead9720a4c760b99e4011b30f1f97a 1550 SUPERFAMILY SSF52540 550 741 1.72E-24 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOT_020000382 48ead9720a4c760b99e4011b30f1f97a 1550 Gene3D G3DSA:3.40.50.300 510 747 9.5E-37 T 01-11-2018 TOT_020000382 48ead9720a4c760b99e4011b30f1f97a 1550 Pfam PF00005 ABC transporter 1272 1465 2.3E-15 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOT_020000382 48ead9720a4c760b99e4011b30f1f97a 1550 SMART SM00382 562 750 0.24 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000382 48ead9720a4c760b99e4011b30f1f97a 1550 SMART SM00382 1281 1521 0.02 T 01-11-2018 IPR003593 AAA+ ATPase domain TOT_020000382 48ead9720a4c760b99e4011b30f1f97a 1550 Gene3D G3DSA:1.20.1560.10 839 1175 7.5E-11 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TOT_020000113 f5b5cdf471825968eaf7ad41a5b5e87e 425 Pfam PF12872 OST-HTH/LOTUS domain 311 369 8.5E-7 T 01-11-2018 IPR025605 OST-HTH/LOTUS domain TOT_020000113 f5b5cdf471825968eaf7ad41a5b5e87e 425 Pfam PF14418 OST-HTH Associated domain 233 299 6.6E-18 T 01-11-2018 IPR025677 OST-HTH associated domain TOT_030000320 7e96a9e5897eb987750ebc636e7234a4 218 Pfam PF03937 Flavinator of succinate dehydrogenase 142 204 9.3E-5 T 01-11-2018 IPR005631 Flavinator of succinate dehydrogenase TOT_030000320 7e96a9e5897eb987750ebc636e7234a4 218 Gene3D G3DSA:1.10.150.250 140 213 4.6E-5 T 01-11-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily TOT_010000463 2ecb24976bd0b675439f3d4b6335b544 1069 Pfam PF02383 SacI homology domain 83 436 7.3E-54 T 01-11-2018 IPR002013 SAC domain GO:0042578 TOT_010001366 636ffbc37c46ad98e28e8efb30c2eb7c 458 Gene3D G3DSA:3.30.70.330 239 327 5.6E-20 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_010001366 636ffbc37c46ad98e28e8efb30c2eb7c 458 SMART SM00360 247 312 3.9E-16 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_010001366 636ffbc37c46ad98e28e8efb30c2eb7c 458 SMART SM00360 331 400 1.1E-10 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_010001366 636ffbc37c46ad98e28e8efb30c2eb7c 458 SUPERFAMILY SSF54928 246 393 4.89E-34 T 01-11-2018 IPR035979 RNA-binding domain superfamily GO:0003676 TOT_010001366 636ffbc37c46ad98e28e8efb30c2eb7c 458 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 248 304 1.7E-13 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_010001366 636ffbc37c46ad98e28e8efb30c2eb7c 458 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 332 397 1.7E-14 T 01-11-2018 IPR000504 RNA recognition motif domain GO:0003676 TOT_010001366 636ffbc37c46ad98e28e8efb30c2eb7c 458 Gene3D G3DSA:3.30.70.330 329 406 4.9E-18 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_040000578 da928778ef22622a83b17fb67e6d5309 181 Gene3D G3DSA:1.10.8.1120 1 73 2.7E-13 T 01-11-2018 IPR038294 SLBP, RNA-binding domain superfamily Reactome: R-HSA-109688|Reactome: R-HSA-159230|Reactome: R-HSA-77588 TOT_040000578 da928778ef22622a83b17fb67e6d5309 181 Pfam PF15247 Histone RNA hairpin-binding protein RNA-binding domain 2 72 1.9E-18 T 01-11-2018 IPR029344 Histone RNA hairpin-binding protein, RNA-binding domain GO:0003723 Reactome: R-HSA-109688|Reactome: R-HSA-159230|Reactome: R-HSA-77588 TOT_030000759 7a17d51d83d27adf8d1e99ad1d27e6dd 416 Gene3D G3DSA:1.10.472.30 26 174 7.7E-10 T 01-11-2018 IPR036575 Transcription elongation factor S-II, central domain superfamily GO:0006351 TOT_030000759 7a17d51d83d27adf8d1e99ad1d27e6dd 416 Pfam PF07500 Transcription factor S-II (TFIIS), central domain 61 163 6.6E-13 T 01-11-2018 IPR003618 Transcription elongation factor S-II, central domain GO:0006351 TOT_030000759 7a17d51d83d27adf8d1e99ad1d27e6dd 416 SUPERFAMILY SSF46942 75 152 2.62E-12 T 01-11-2018 IPR036575 Transcription elongation factor S-II, central domain superfamily GO:0006351 TOT_010000368 71d00000b77dfa5974c1f39de3fcf7f5 1269 Pfam PF04385 Domain of unknown function, DUF529 632 702 3.6E-8 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000368 71d00000b77dfa5974c1f39de3fcf7f5 1269 Pfam PF04385 Domain of unknown function, DUF529 168 221 4.7E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000837 18bb7e7a27d7c8f1b9cffa38f4130e78 391 Pfam PF04385 Domain of unknown function, DUF529 247 309 6.6E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000837 18bb7e7a27d7c8f1b9cffa38f4130e78 391 Pfam PF04385 Domain of unknown function, DUF529 64 110 3.0E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010001050 b0cb7ef2c1d0429086d494c990bf5605 827 SUPERFAMILY SSF50978 431 818 5.23E-5 T 01-11-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 TOT_030000445 e805f20989c142de8e317d8ae16dd501 273 SMART SM00244 25 187 2.8E-35 T 01-11-2018 IPR001107 Band 7 domain TOT_030000445 e805f20989c142de8e317d8ae16dd501 273 PRINTS PR00679 Prohibitin signature 134 150 2.1E-60 T 01-11-2018 IPR000163 Prohibitin GO:0016020 Reactome: R-HSA-8949664 TOT_030000445 e805f20989c142de8e317d8ae16dd501 273 PRINTS PR00679 Prohibitin signature 88 107 2.1E-60 T 01-11-2018 IPR000163 Prohibitin GO:0016020 Reactome: R-HSA-8949664 TOT_030000445 e805f20989c142de8e317d8ae16dd501 273 PRINTS PR00679 Prohibitin signature 205 221 2.1E-60 T 01-11-2018 IPR000163 Prohibitin GO:0016020 Reactome: R-HSA-8949664 TOT_030000445 e805f20989c142de8e317d8ae16dd501 273 PRINTS PR00679 Prohibitin signature 182 205 2.1E-60 T 01-11-2018 IPR000163 Prohibitin GO:0016020 Reactome: R-HSA-8949664 TOT_030000445 e805f20989c142de8e317d8ae16dd501 273 PRINTS PR00679 Prohibitin signature 157 176 2.1E-60 T 01-11-2018 IPR000163 Prohibitin GO:0016020 Reactome: R-HSA-8949664 TOT_030000445 e805f20989c142de8e317d8ae16dd501 273 PRINTS PR00679 Prohibitin signature 111 129 2.1E-60 T 01-11-2018 IPR000163 Prohibitin GO:0016020 Reactome: R-HSA-8949664 TOT_030000445 e805f20989c142de8e317d8ae16dd501 273 PRINTS PR00679 Prohibitin signature 70 86 2.1E-60 T 01-11-2018 IPR000163 Prohibitin GO:0016020 Reactome: R-HSA-8949664 TOT_030000445 e805f20989c142de8e317d8ae16dd501 273 SUPERFAMILY SSF117892 58 193 2.62E-15 T 01-11-2018 IPR036013 Band 7/SPFH domain superfamily TOT_030000445 e805f20989c142de8e317d8ae16dd501 273 Pfam PF01145 SPFH domain / Band 7 family 28 204 2.0E-24 T 01-11-2018 IPR001107 Band 7 domain TOT_010000756 f52e6a9032b9336e4f9bc57f5fd67c93 91 SUPERFAMILY SSF144122 30 89 2.62E-18 T 01-11-2018 IPR035427 Tim10-like domain superfamily Reactome: R-HSA-1268020 TOT_010000756 f52e6a9032b9336e4f9bc57f5fd67c93 91 Gene3D G3DSA:1.10.287.810 9 91 4.4E-25 T 01-11-2018 IPR035427 Tim10-like domain superfamily Reactome: R-HSA-1268020 TOT_010000756 f52e6a9032b9336e4f9bc57f5fd67c93 91 Pfam PF02953 Tim10/DDP family zinc finger 27 85 1.3E-18 T 01-11-2018 IPR004217 Tim10-like Reactome: R-HSA-1268020 TOT_010001165 15a21aeb0e1a26179332fbf24b7b4d9c 590 Pfam PF04385 Domain of unknown function, DUF529 500 570 1.2E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010001165 15a21aeb0e1a26179332fbf24b7b4d9c 590 Pfam PF04385 Domain of unknown function, DUF529 302 355 2.8E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_030000686 72b32882417e8e28abae7147dca01759 178 SMART SM01416 1 144 3.5E-89 T 01-11-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_030000686 72b32882417e8e28abae7147dca01759 178 ProSitePatterns PS00526 Ribosomal protein L19e signature. 5 24 - T 01-11-2018 IPR023638 Ribosomal protein L19/L19e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_030000686 72b32882417e8e28abae7147dca01759 178 Gene3D G3DSA:1.10.1200.240 55 178 1.7E-46 T 01-11-2018 TOT_030000686 72b32882417e8e28abae7147dca01759 178 Pfam PF01280 Ribosomal protein L19e 2 144 1.6E-59 T 01-11-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_030000686 72b32882417e8e28abae7147dca01759 178 Gene3D G3DSA:1.10.1650.10 1 53 4.7E-28 T 01-11-2018 IPR015972 Ribosomal protein L19/L19e, domain 1 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_030000686 72b32882417e8e28abae7147dca01759 178 SUPERFAMILY SSF48140 1 141 1.19E-58 T 01-11-2018 IPR035970 Ribosomal protein L19/L19e superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TOT_030000934 8e760484b2f772705a39e3a76999ac4f 606 Pfam PF04188 Mannosyltransferase (PIG-V) 112 606 9.7E-17 T 01-11-2018 IPR007315 GPI mannosyltransferase 2 GO:0004584|GO:0006506 Reactome: R-HSA-162710 TOT_040000277 c08330353394abc3548c88c82b922666 80 Pfam PF01428 AN1-like Zinc finger 30 66 3.6E-10 T 01-11-2018 IPR000058 Zinc finger, AN1-type GO:0008270 TOT_040000277 c08330353394abc3548c88c82b922666 80 SMART SM00154 22 68 9.3E-4 T 01-11-2018 IPR000058 Zinc finger, AN1-type GO:0008270 TOT_040000277 c08330353394abc3548c88c82b922666 80 SUPERFAMILY SSF118310 11 66 3.27E-13 T 01-11-2018 IPR035896 AN1-like Zinc finger TOT_040000277 c08330353394abc3548c88c82b922666 80 Gene3D G3DSA:4.10.1110.10 17 77 1.9E-9 T 01-11-2018 IPR035896 AN1-like Zinc finger TOT_010000851 8e7ea5d3c880d21eb24b1a0e796429b5 943 Pfam PF02383 SacI homology domain 57 346 5.2E-61 T 01-11-2018 IPR002013 SAC domain GO:0042578 TOT_020001037 80566bd80e2b1e0c25ca7efa65c20d87 394 SUPERFAMILY SSF52058 10 222 1.7E-12 T 01-11-2018 TOT_020001037 80566bd80e2b1e0c25ca7efa65c20d87 394 Gene3D G3DSA:3.80.10.10 120 255 1.2E-9 T 01-11-2018 IPR032675 Leucine-rich repeat domain superfamily TOT_020001037 80566bd80e2b1e0c25ca7efa65c20d87 394 Pfam PF13855 Leucine rich repeat 131 186 3.7E-7 T 01-11-2018 IPR001611 Leucine-rich repeat GO:0005515 TOT_020001037 80566bd80e2b1e0c25ca7efa65c20d87 394 Gene3D G3DSA:3.80.10.10 3 103 2.2E-6 T 01-11-2018 IPR032675 Leucine-rich repeat domain superfamily TOT_010001077 3eaf15a14c29af0abc4613f868cae0d7 891 Pfam PF16953 Protein-only RNase P 450 607 6.3E-9 T 01-11-2018 IPR031595 Protein-only RNase P, C-terminal Reactome: R-HSA-6785470|Reactome: R-HSA-6787450|Reactome: R-HSA-8868766 TOT_030000209 07a504e40ded118df1a0aedefe1bc124 178 ProSitePatterns PS01358 Zinc finger RanBP2-type signature. 150 169 - T 01-11-2018 IPR001876 Zinc finger, RanBP2-type TOT_010000717 7fc809803df49f9284a0590b00f797ae 198 Gene3D G3DSA:3.30.450.60 43 198 2.1E-50 T 01-11-2018 TOT_010000717 7fc809803df49f9284a0590b00f797ae 198 Pfam PF01217 Clathrin adaptor complex small chain 43 191 2.1E-33 T 01-11-2018 IPR022775 AP complex, mu/sigma subunit TOT_010000717 7fc809803df49f9284a0590b00f797ae 198 PIRSF PIRSF015588 43 197 1.9E-42 T 01-11-2018 IPR016635 Adaptor protein complex, sigma subunit GO:0015031 TOT_010000717 7fc809803df49f9284a0590b00f797ae 198 SUPERFAMILY SSF64356 43 188 3.62E-34 T 01-11-2018 IPR011012 Longin-like domain superfamily TOT_020000820 e74633c39ce60c9536d1a163a9844707 199 Pfam PF04385 Domain of unknown function, DUF529 36 104 5.5E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000013 6381438e8d7b03109f72dbf2de6fc22d 1709 Pfam PF04385 Domain of unknown function, DUF529 28 97 3.1E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000386 0728aa5bac386dfbd08107f09fe55e7b 471 Pfam PF02104 SURF1 family 152 449 9.8E-32 T 01-11-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TOT_040000688 9647e06343bf07d5973bab754ca21237 1052 SUPERFAMILY SSF48371 19 854 1.08E-63 T 01-11-2018 IPR016024 Armadillo-type fold TOT_040000688 9647e06343bf07d5973bab754ca21237 1052 Pfam PF01602 Adaptin N terminal region 24 550 1.8E-69 T 01-11-2018 IPR002553 Clathrin/coatomer adaptor, adaptin-like, N-terminal GO:0006886|GO:0016192|GO:0030117 TOT_040000688 9647e06343bf07d5973bab754ca21237 1052 PIRSF PIRSF037094 756 1047 1.0E-10 T 01-11-2018 IPR017107 Adaptor protein complex AP-1, gamma subunit GO:0005794|GO:0016192|GO:0030121 Reactome: R-HSA-432720 TOT_040000688 9647e06343bf07d5973bab754ca21237 1052 PIRSF PIRSF037094 610 703 23.0 T 01-11-2018 IPR017107 Adaptor protein complex AP-1, gamma subunit GO:0005794|GO:0016192|GO:0030121 Reactome: R-HSA-432720 TOT_040000688 9647e06343bf07d5973bab754ca21237 1052 PIRSF PIRSF037094 1 558 3.9E-110 T 01-11-2018 IPR017107 Adaptor protein complex AP-1, gamma subunit GO:0005794|GO:0016192|GO:0030121 Reactome: R-HSA-432720 TOT_040000688 9647e06343bf07d5973bab754ca21237 1052 Gene3D G3DSA:1.25.10.10 1 560 1.1E-114 T 01-11-2018 IPR011989 Armadillo-like helical TOT_040000688 9647e06343bf07d5973bab754ca21237 1052 Gene3D G3DSA:1.25.10.10 760 855 6.1E-8 T 01-11-2018 IPR011989 Armadillo-like helical TOT_030000197 ea4d9e7a9b1d3398d7c57ef9e1d088c9 1543 Pfam PF00443 Ubiquitin carboxyl-terminal hydrolase 1235 1532 2.7E-30 T 01-11-2018 IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase GO:0016579|GO:0036459 TOT_030000197 ea4d9e7a9b1d3398d7c57ef9e1d088c9 1543 Gene3D G3DSA:3.90.70.10 1216 1535 1.9E-60 T 01-11-2018 TOT_030000197 ea4d9e7a9b1d3398d7c57ef9e1d088c9 1543 SUPERFAMILY SSF54001 1231 1535 6.08E-64 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily TOT_030000197 ea4d9e7a9b1d3398d7c57ef9e1d088c9 1543 ProSitePatterns PS00972 Ubiquitin specific protease (USP) domain signature 1. 1236 1251 - T 01-11-2018 IPR018200 Ubiquitin specific protease, conserved site GO:0006511|GO:0036459 TOT_010000836 d10485cddecc8c6f18083cd643310e75 179 Gene3D G3DSA:2.30.30.1190 51 101 2.3E-5 T 01-11-2018 TOT_010000836 d10485cddecc8c6f18083cd643310e75 179 SUPERFAMILY SSF90229 61 93 4.71E-6 T 01-11-2018 IPR036855 Zinc finger, CCCH-type superfamily GO:0046872 TOT_010001280 2968a4deb647152af50ed44311117918 1298 SUPERFAMILY SSF48371 619 1131 1.15E-12 T 01-11-2018 IPR016024 Armadillo-type fold TOT_010001280 2968a4deb647152af50ed44311117918 1298 Gene3D G3DSA:1.25.10.10 781 866 2.6E-7 T 01-11-2018 IPR011989 Armadillo-like helical TOT_010001280 2968a4deb647152af50ed44311117918 1298 Gene3D G3DSA:1.25.10.10 995 1202 8.9E-19 T 01-11-2018 IPR011989 Armadillo-like helical TOT_010001280 2968a4deb647152af50ed44311117918 1298 Gene3D G3DSA:1.25.10.10 570 765 2.3E-39 T 01-11-2018 IPR011989 Armadillo-like helical TOT_010001122 775db4cf1ebed2a6f8f891d73ed9cfdd 140 Pfam PF00583 Acetyltransferase (GNAT) family 39 128 3.3E-9 T 01-11-2018 IPR000182 GNAT domain TOT_010001122 775db4cf1ebed2a6f8f891d73ed9cfdd 140 SUPERFAMILY SSF55729 16 134 1.5E-16 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase TOT_010001122 775db4cf1ebed2a6f8f891d73ed9cfdd 140 Gene3D G3DSA:3.40.630.30 2 135 6.1E-14 T 01-11-2018 TOT_030000014 65d37da546bfed7050d5b0f4a391280a 982 Pfam PF04385 Domain of unknown function, DUF529 391 435 2.9E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000164 fe0acdef2f04bbc51dccbbd7f2bddd8e 243 PIRSF PIRSF000239 45 243 5.5E-56 T 01-11-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TOT_010000164 fe0acdef2f04bbc51dccbbd7f2bddd8e 243 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 204 238 3.3E-9 T 01-11-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TOT_010000164 fe0acdef2f04bbc51dccbbd7f2bddd8e 243 Pfam PF00578 AhpC/TSA family 52 183 4.9E-29 T 01-11-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TOT_010000164 fe0acdef2f04bbc51dccbbd7f2bddd8e 243 SUPERFAMILY SSF52833 50 238 9.53E-58 T 01-11-2018 IPR036249 Thioredoxin-like superfamily TOT_010000164 fe0acdef2f04bbc51dccbbd7f2bddd8e 243 Gene3D G3DSA:3.40.30.10 44 241 6.8E-67 T 01-11-2018 TOT_040000866 27b00e69d395ea404ff409d7dc5d9387 192 Pfam PF04385 Domain of unknown function, DUF529 43 92 2.2E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000832 6519b8f1d33fd9f7ea1a4f78c95de0ec 197 Gene3D G3DSA:3.40.1280.30 2 196 4.6E-56 T 01-11-2018 IPR038459 tRNA methyltransferase TRM10-type domain superfamily TOT_040000832 6519b8f1d33fd9f7ea1a4f78c95de0ec 197 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 31 196 1.9E-22 T 01-11-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TOT_040000548 6f01e99f75ecdb8179938228304594b2 1137 Pfam PF10154 Uncharacterized conserved protein (DUF2362) 878 1033 1.5E-10 T 01-11-2018 IPR019311 Protein of unknown function DUF2362 TOT_030000109 9c22b8aba2669a6029b82ecb734c753b 2391 SUPERFAMILY SSF48371 1763 2195 5.37E-5 T 01-11-2018 IPR016024 Armadillo-type fold TOT_040000066 fe63f5733c627a81b626819a03503351 590 Pfam PF00847 AP2 domain 532 582 1.1E-12 T 01-11-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 TOT_030000605 bb6c0743af8217bb1067c2360af02b08 171 Pfam PF07368 Protein of unknown function (DUF1487) 28 150 2.8E-4 T 01-11-2018 IPR009961 Protein of unknown function DUF1487 TOT_040000887 d971e5afa52428ac9133ec47effbf28e 652 Pfam PF03914 CBF/Mak21 family 474 640 2.7E-8 T 01-11-2018 IPR005612 CCAAT-binding factor TOT_010000543 30bc02a8656486a5e6df2d40c6b12077 3138 Pfam PF04385 Domain of unknown function, DUF529 2188 2251 1.7E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000939 aae8cb0a1c9598827201365c9bdaa763 392 Pfam PF14360 PAP2 superfamily C-terminal 199 269 7.3E-16 T 01-11-2018 IPR025749 Sphingomyelin synthase-like domain Reactome: R-HSA-1660661 TOT_040000939 aae8cb0a1c9598827201365c9bdaa763 392 Gene3D G3DSA:1.20.144.10 205 303 4.7E-7 T 01-11-2018 TOT_010000424 8ae53b97375187ec83106dd6659ae47a 994 SUPERFAMILY SSF103473 90 420 9.02E-15 T 01-11-2018 IPR036259 MFS transporter superfamily TOT_010000424 8ae53b97375187ec83106dd6659ae47a 994 Gene3D G3DSA:1.20.1250.20 85 417 5.1E-13 T 01-11-2018 TOT_010000443 0aa849b70f2cce86ce950097d3aff80c 472 Pfam PF04385 Domain of unknown function, DUF529 270 339 1.2E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000679 9ae784ee349a1a2b51328390c1fea9d0 358 Pfam PF04385 Domain of unknown function, DUF529 147 220 8.2E-12 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000679 9ae784ee349a1a2b51328390c1fea9d0 358 Pfam PF04385 Domain of unknown function, DUF529 29 102 4.1E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000777 0b1a81cf0563e583624391d211950a34 192 Gene3D G3DSA:1.10.287.660 39 96 1.1E-22 T 01-11-2018 IPR029012 Helix hairpin bin domain superfamily TOT_020000777 0b1a81cf0563e583624391d211950a34 192 Pfam PF06246 Isy1-like splicing family 1 189 3.8E-66 T 01-11-2018 IPR009360 Pre-mRNA-splicing factor Isy1 GO:0000350 Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-72163 TOT_020000777 0b1a81cf0563e583624391d211950a34 192 SUPERFAMILY SSF140102 27 102 8.63E-28 T 01-11-2018 IPR037200 Pre-mRNA-splicing factor Isy1 superfamily GO:0000350 Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-72163 TOT_030000461 c4adf496521ab8b1edf440b80bb7892b 412 Gene3D G3DSA:1.25.40.90 151 294 5.7E-15 T 01-11-2018 IPR008942 ENTH/VHS TOT_020000197 ff3d5ead2a4c31a62256da083f90584a 252 Pfam PF04385 Domain of unknown function, DUF529 139 215 1.8E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000454 9b2552668473632129fcf1f7ca631036 320 SMART SM00240 79 130 5.9E-8 T 01-11-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TOT_020000454 9b2552668473632129fcf1f7ca631036 320 Pfam PF00498 FHA domain 80 147 5.6E-15 T 01-11-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TOT_020000454 9b2552668473632129fcf1f7ca631036 320 Gene3D G3DSA:2.60.200.20 26 160 3.5E-26 T 01-11-2018 TOT_020000454 9b2552668473632129fcf1f7ca631036 320 SUPERFAMILY SSF49879 39 158 1.01E-22 T 01-11-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 TOT_020000630 5504047519bbf5ac03a7a4658abc1b49 211 SUPERFAMILY SSF110324 44 125 3.84E-11 T 01-11-2018 TOT_020000630 5504047519bbf5ac03a7a4658abc1b49 211 Pfam PF01016 Ribosomal L27 protein 44 124 8.2E-10 T 01-11-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TOT_020000630 5504047519bbf5ac03a7a4658abc1b49 211 Gene3D G3DSA:2.40.50.100 49 128 3.3E-8 T 01-11-2018 TOT_030000280 8fd80d8ec96ba8aa150c64ba1d3d125b 719 Pfam PF09743 E3 UFM1-protein ligase 1 4 264 2.6E-66 T 01-11-2018 IPR018611 E3 UFM1-protein ligase 1 Reactome: R-HSA-983168 TOT_010000907 e29a84743b17499b18ee41570e27a5c2 470 SUPERFAMILY SSF57184 93 232 9.81E-7 T 01-11-2018 IPR009030 Growth factor receptor cysteine-rich domain superfamily TOT_020001086 9aee893552f4513dcfaeecdc9c82fdfc 534 ProSitePatterns PS00018 EF-hand calcium-binding domain. 507 519 - T 01-11-2018 IPR018247 EF-Hand 1, calcium-binding site TOT_020001086 9aee893552f4513dcfaeecdc9c82fdfc 534 ProSitePatterns PS00018 EF-hand calcium-binding domain. 433 445 - T 01-11-2018 IPR018247 EF-Hand 1, calcium-binding site TOT_020001086 9aee893552f4513dcfaeecdc9c82fdfc 534 SUPERFAMILY SSF47473 423 525 2.13E-6 T 01-11-2018 IPR011992 EF-hand domain pair TOT_020000492 b4e5d8be4c6db4e968f65a5a4ab3a5d9 1098 Pfam PF07529 HSA 65 108 1.7E-4 T 01-11-2018 IPR014012 Helicase/SANT-associated domain TOT_020000077 c3fbf8f229ebc19fcb4d8ae9f7dd327d 341 Pfam PF04385 Domain of unknown function, DUF529 65 132 1.1E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000334 0b3c0ad5806360591b68fd14c5d0f3e9 127 Pfam PF01521 Iron-sulphur cluster biosynthesis 6 120 5.0E-10 T 01-11-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 TOT_040000334 0b3c0ad5806360591b68fd14c5d0f3e9 127 Gene3D G3DSA:2.60.300.12 3 126 2.3E-21 T 01-11-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 TOT_040000334 0b3c0ad5806360591b68fd14c5d0f3e9 127 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 7 123 6.2E-18 T 01-11-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 TOT_040000334 0b3c0ad5806360591b68fd14c5d0f3e9 127 SUPERFAMILY SSF89360 4 107 5.36E-16 T 01-11-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 TOT_040000231 2a249359c39b8f2eb9b79ba48dfbe617 350 SUPERFAMILY SSF55729 206 301 7.15E-13 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase TOT_040000231 2a249359c39b8f2eb9b79ba48dfbe617 350 Pfam PF00583 Acetyltransferase (GNAT) family 205 277 5.2E-9 T 01-11-2018 IPR000182 GNAT domain TOT_010000805 e6be51fb97529a36f8f51e0e93dc1d9f 370 Gene3D G3DSA:3.30.70.330 269 361 6.3E-6 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TOT_010000805 e6be51fb97529a36f8f51e0e93dc1d9f 370 SMART SM00443 190 236 1.8E-12 T 01-11-2018 IPR000467 G-patch domain GO:0003676 TOT_010000805 e6be51fb97529a36f8f51e0e93dc1d9f 370 SUPERFAMILY SSF54928 277 360 2.01E-5 T 01-11-2018 IPR035979 RNA-binding domain superfamily GO:0003676 TOT_010000805 e6be51fb97529a36f8f51e0e93dc1d9f 370 Pfam PF01585 G-patch domain 193 233 1.1E-14 T 01-11-2018 IPR000467 G-patch domain GO:0003676 TOT_010000120 9fe1d4b618fa8cb303608b48a10fd35f 396 Pfam PF05542 Protein of unknown function (DUF760) 300 393 4.4E-9 T 01-11-2018 IPR008479 Protein of unknown function DUF760 TOT_010000120 9fe1d4b618fa8cb303608b48a10fd35f 396 Pfam PF05542 Protein of unknown function (DUF760) 189 259 4.7E-10 T 01-11-2018 IPR008479 Protein of unknown function DUF760 TOT_040000486 8edc881c33adc0002b442dd4cf086fda 818 Pfam PF04385 Domain of unknown function, DUF529 26 98 1.2E-7 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000862 e1946bcb503ef73577e7f37c69764986 137 Pfam PF04032 RNAse P Rpr2/Rpp21/SNM1 subunit domain 33 127 2.7E-14 T 01-11-2018 IPR007175 RNAse P, Rpr2/Rpp21 subunit Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TOT_010001160 21497483539bb4ff42d97516a3a28a62 182 Pfam PF04385 Domain of unknown function, DUF529 103 152 1.6E-7 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000049 734ef4fe5b2ca5c76e027a6315c7a0b0 273 SUPERFAMILY SSF57903 3 64 1.39E-8 T 01-11-2018 IPR011011 Zinc finger, FYVE/PHD-type TOT_020000049 734ef4fe5b2ca5c76e027a6315c7a0b0 273 Gene3D G3DSA:3.30.40.10 1 74 1.1E-5 T 01-11-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type TOT_040000581 cf20ff15ef508b69f2c21c12cfaf6585 401 Pfam PF08613 Cyclin 34 137 4.9E-30 T 01-11-2018 IPR013922 Cyclin PHO80-like GO:0000079|GO:0019901 TOT_040000581 cf20ff15ef508b69f2c21c12cfaf6585 401 Gene3D G3DSA:1.10.472.10 6 187 2.2E-47 T 01-11-2018 TOT_040000581 cf20ff15ef508b69f2c21c12cfaf6585 401 SUPERFAMILY SSF47954 47 137 2.55E-13 T 01-11-2018 IPR036915 Cyclin-like superfamily TOT_040000081 6670e11992b84db4411e8135cadfc553 227 Pfam PF06102 rRNA biogenesis protein RRP36 16 217 1.3E-28 T 01-11-2018 IPR009292 rRNA biogenesis protein RRP36 GO:0000469 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TOT_040000834 4aa18b10c7844fa23302abf6b1aa45a1 805 Pfam PF04385 Domain of unknown function, DUF529 617 658 1.2E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000484 5983b4154c9f7f6cee28a864c1b1e3a5 655 Pfam PF00847 AP2 domain 447 494 1.6E-6 T 01-11-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 TOT_040000043 48340660846727a5680e3d450f37142f 808 SUPERFAMILY SSF52151 220 474 1.86E-11 T 01-11-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TOT_020000671 3b616ceca4d21419b9f6b0bf05948690 170 SUPERFAMILY SSF141678 1 166 4.58E-36 T 01-11-2018 TOT_020000671 3b616ceca4d21419b9f6b0bf05948690 170 Pfam PF05907 Eukaryotic protein of unknown function (DUF866) 6 140 9.2E-24 T 01-11-2018 IPR008584 Protein of unknown function DUF866, eukaryotic TOT_040000627 7c4a2f699df7499e815fd1c516704cf6 83 SUPERFAMILY SSF82657 3 81 5.75E-29 T 01-11-2018 IPR036065 BolA-like superfamily TOT_040000627 7c4a2f699df7499e815fd1c516704cf6 83 Pfam PF01722 BolA-like protein 15 75 4.2E-18 T 01-11-2018 IPR002634 BolA protein TOT_040000627 7c4a2f699df7499e815fd1c516704cf6 83 PIRSF PIRSF003113 1 83 3.0E-29 T 01-11-2018 IPR002634 BolA protein TOT_040000627 7c4a2f699df7499e815fd1c516704cf6 83 Gene3D G3DSA:3.30.300.90 1 82 1.5E-33 T 01-11-2018 TOT_010001044 83446dcafa34d3a23b4e4b58103ceaf0 488 SUPERFAMILY SSF56112 264 441 2.38E-9 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily TOT_010001334 7d233a9c0cd2baa25fe074d1f635e4b8 571 Pfam PF08783 DWNN domain 8 88 1.8E-8 T 01-11-2018 IPR014891 DWNN domain GO:0005634|GO:0008270 Reactome: R-HSA-983168 TOT_010001334 7d233a9c0cd2baa25fe074d1f635e4b8 571 SMART SM01180 8 89 2.1E-8 T 01-11-2018 IPR014891 DWNN domain GO:0005634|GO:0008270 Reactome: R-HSA-983168 TOT_010001334 7d233a9c0cd2baa25fe074d1f635e4b8 571 Gene3D G3DSA:3.30.40.10 109 246 2.3E-6 T 01-11-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type TOT_020000425 2d3e13da1c5260985b68480db644c25a 839 SUPERFAMILY SSF50978 50 457 2.93E-13 T 01-11-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 TOT_020000425 2d3e13da1c5260985b68480db644c25a 839 Pfam PF08662 Eukaryotic translation initiation factor eIF2A 278 467 1.0E-51 T 01-11-2018 IPR013979 Translation initiation factor, beta propellor-like domain TOT_010000819 89827f1fb60f96ba9945a75867350b46 924 Pfam PF00013 KH domain 779 814 2.1E-4 T 01-11-2018 IPR004088 K Homology domain, type 1 GO:0003723 TOT_010000819 89827f1fb60f96ba9945a75867350b46 924 Gene3D G3DSA:3.30.310.210 701 870 2.1E-7 T 01-11-2018 TOT_010000819 89827f1fb60f96ba9945a75867350b46 924 SUPERFAMILY SSF54791 768 867 6.01E-6 T 01-11-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TOT_010000521 9403e4cc83dc31ff87b01f3f3c56f15d 475 Pfam PF04385 Domain of unknown function, DUF529 236 281 5.0E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_030000874 073ad06855bc40770d02770984323bbc 638 Pfam PF04385 Domain of unknown function, DUF529 49 108 8.5E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_030000874 073ad06855bc40770d02770984323bbc 638 Pfam PF04385 Domain of unknown function, DUF529 370 418 2.6E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_030000874 073ad06855bc40770d02770984323bbc 638 Pfam PF04385 Domain of unknown function, DUF529 253 315 1.3E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_030000874 073ad06855bc40770d02770984323bbc 638 Pfam PF04385 Domain of unknown function, DUF529 161 201 1.1E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000549 a4b08e8148fe33f943ab54b0d9918d06 275 Pfam PF04385 Domain of unknown function, DUF529 111 159 1.1E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_030000636 37db182d44a7214dd7172bdf96321a0e 444 Pfam PF04385 Domain of unknown function, DUF529 87 146 2.8E-9 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000343 98e4765e4d9c6863e8a87384ec4b4203 482 Pfam PF04385 Domain of unknown function, DUF529 177 238 4.3E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000343 98e4765e4d9c6863e8a87384ec4b4203 482 Pfam PF04385 Domain of unknown function, DUF529 277 327 1.2E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000343 98e4765e4d9c6863e8a87384ec4b4203 482 Pfam PF04385 Domain of unknown function, DUF529 386 427 2.4E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000311 fdf1132bc332a6303df841a9e75ae777 451 SMART SM00297 32 140 3.4E-24 T 01-11-2018 IPR001487 Bromodomain GO:0005515 TOT_020000311 fdf1132bc332a6303df841a9e75ae777 451 Gene3D G3DSA:1.20.920.10 29 145 9.3E-28 T 01-11-2018 IPR036427 Bromodomain-like superfamily GO:0005515 TOT_020000311 fdf1132bc332a6303df841a9e75ae777 451 SUPERFAMILY SSF47370 29 139 9.68E-29 T 01-11-2018 IPR036427 Bromodomain-like superfamily GO:0005515 TOT_020000311 fdf1132bc332a6303df841a9e75ae777 451 Pfam PF00439 Bromodomain 44 125 6.2E-17 T 01-11-2018 IPR001487 Bromodomain GO:0005515 TOT_020000311 fdf1132bc332a6303df841a9e75ae777 451 PRINTS PR00503 Bromodomain signature 102 121 4.5E-8 T 01-11-2018 IPR001487 Bromodomain GO:0005515 TOT_020000311 fdf1132bc332a6303df841a9e75ae777 451 PRINTS PR00503 Bromodomain signature 67 83 4.5E-8 T 01-11-2018 IPR001487 Bromodomain GO:0005515 TOT_040000623 aaf2341375f1ab0c2d70e25eaf5511c3 281 SUPERFAMILY SSF52833 10 149 5.7E-9 T 01-11-2018 IPR036249 Thioredoxin-like superfamily TOT_040000623 aaf2341375f1ab0c2d70e25eaf5511c3 281 Gene3D G3DSA:3.40.30.10 61 209 1.7E-8 T 01-11-2018 TOT_020001033 85da9f72618b7a7997fd8791023c3fbe 427 Pfam PF08627 CRT-like, chloroquine-resistance transporter-like 57 382 9.6E-50 T 01-11-2018 IPR013936 Chloroquine-resistance transporter-like TOT_040000432 2d2daa8acf5db3ee88b597a7ee09774a 705 Pfam PF14418 OST-HTH Associated domain 594 658 4.2E-19 T 01-11-2018 IPR025677 OST-HTH associated domain TOT_010000721 57a18595a4e6bc118518e94f12e93bda 909 SUPERFAMILY SSF81383 13 61 3.05E-5 T 01-11-2018 IPR036047 F-box-like domain superfamily GO:0005515 TOT_010000721 57a18595a4e6bc118518e94f12e93bda 909 Pfam PF00646 F-box domain 13 47 0.0025 T 01-11-2018 IPR001810 F-box domain GO:0005515 TOT_020000742 65b81a067118a232e54d0d0ed8c785ce 227 Pfam PF04385 Domain of unknown function, DUF529 92 147 2.9E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000981 60eec662c8364408fa50a25cda6591d5 696 Pfam PF04385 Domain of unknown function, DUF529 216 263 7.5E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000981 60eec662c8364408fa50a25cda6591d5 696 Pfam PF04385 Domain of unknown function, DUF529 310 375 3.0E-7 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000579 0bb119964ea60ae8000665a651c33b50 866 Pfam PF04385 Domain of unknown function, DUF529 43 101 8.7E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000217 1fc98c09bd3797337e824953556113df 170 Pfam PF01597 Glycine cleavage H-protein 68 143 9.6E-9 T 01-11-2018 IPR033753 Glycine cleavage system H-protein/Simiate TOT_020000217 1fc98c09bd3797337e824953556113df 170 SUPERFAMILY SSF51230 64 142 1.41E-12 T 01-11-2018 IPR011053 Single hybrid motif TOT_020000217 1fc98c09bd3797337e824953556113df 170 Gene3D G3DSA:2.40.50.100 64 170 3.1E-19 T 01-11-2018 TOT_020000208 d64eabef6d841f486edb5ae78e3e93bf 240 Pfam PF00847 AP2 domain 51 101 1.1E-10 T 01-11-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 TOT_020000342 62191d9ef5f2a93e37bb844651e6284f 950 Pfam PF04385 Domain of unknown function, DUF529 190 240 5.5E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000342 62191d9ef5f2a93e37bb844651e6284f 950 Pfam PF04385 Domain of unknown function, DUF529 68 124 7.5E-7 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000983 4ca50d3a852aeba2e4e9aa1470a8a7bd 553 Pfam PF04385 Domain of unknown function, DUF529 149 203 1.3E-7 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010001169 36f2758ceacdfc97db6ad02f36504b86 430 Pfam PF04385 Domain of unknown function, DUF529 267 321 1.4E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000971 83d35989ce69b93977ca1539c51dbaad 295 Pfam PF13634 Nucleoporin FG repeat region 166 251 1.1E-4 T 01-11-2018 IPR025574 Nucleoporin FG repeat TOT_040000971 83d35989ce69b93977ca1539c51dbaad 295 Pfam PF13634 Nucleoporin FG repeat region 55 141 3.5E-8 T 01-11-2018 IPR025574 Nucleoporin FG repeat TOT_010000578 5eedbbf5233fe17fa960d8087f08c4c9 918 Gene3D G3DSA:3.60.15.10 9 281 6.2E-9 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TOT_010000578 5eedbbf5233fe17fa960d8087f08c4c9 918 SUPERFAMILY SSF56281 12 495 5.0E-23 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TOT_020000489 64f9c8339bc9964ac95112b98f55e2ac 761 Pfam PF01384 Phosphate transporter family 28 745 1.8E-99 T 01-11-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 TOT_010001164 18ba5cfb0b8117bd546f726009977e28 1702 Pfam PF04385 Domain of unknown function, DUF529 319 390 2.1E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010001164 18ba5cfb0b8117bd546f726009977e28 1702 Pfam PF04385 Domain of unknown function, DUF529 916 972 7.2E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000771 5ffaba84933d4f73944a361c3ee939e6 247 SUPERFAMILY SSF57845 21 74 8.24E-10 T 01-11-2018 TOT_020000771 5ffaba84933d4f73944a361c3ee939e6 247 Gene3D G3DSA:3.30.40.200 11 91 3.6E-8 T 01-11-2018 TOT_030000724 9cb0c69b1603970aa9bef08415bab88a 746 Pfam PF04385 Domain of unknown function, DUF529 661 721 1.3E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_030000724 9cb0c69b1603970aa9bef08415bab88a 746 Pfam PF04385 Domain of unknown function, DUF529 282 328 1.0E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010001078 a57dac370e5021ca6b7e4c508ea76181 1332 SUPERFAMILY SSF50978 10 167 9.16E-5 T 01-11-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 TOT_040000940 c1ae9ff970e76d21e58c427f39e2010f 341 SUPERFAMILY SSF103506 78 233 4.18E-7 T 01-11-2018 IPR023395 Mitochondrial carrier domain superfamily TOT_030000940 122eb20c241c6cc4625d1aa5361c9f0b 829 Pfam PF04385 Domain of unknown function, DUF529 57 131 6.8E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000427 7e456c17c0a891626cd6b9eff0f7f7ad 254 SUPERFAMILY SSF53167 19 248 3.34E-23 T 01-11-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TOT_020000427 7e456c17c0a891626cd6b9eff0f7f7ad 254 Gene3D G3DSA:3.40.50.1580 20 253 1.8E-19 T 01-11-2018 TOT_010001267 8df789c5307df7542e8f039a8c014375 147 SUPERFAMILY SSF57667 16 121 8.21E-6 T 01-11-2018 IPR036236 Zinc finger C2H2 superfamily TOT_010001161 0ca294a7900e2b26d8d7f8c3c093dd5f 1107 Pfam PF04385 Domain of unknown function, DUF529 1020 1054 1.1E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000002 ea600648280d575d470f1883850b5808 355 Pfam PF04385 Domain of unknown function, DUF529 264 311 1.6E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000002 ea600648280d575d470f1883850b5808 355 Pfam PF04385 Domain of unknown function, DUF529 164 225 2.2E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000818 6d2840b2ee201c5efef9ce54007ab4c9 2670 Pfam PF04385 Domain of unknown function, DUF529 1769 1836 3.5E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000818 6d2840b2ee201c5efef9ce54007ab4c9 2670 Pfam PF04385 Domain of unknown function, DUF529 1664 1726 3.6E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000731 bd7b6f4365f56564554114f3066c6247 506 Pfam PF00847 AP2 domain 456 500 1.5E-7 T 01-11-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 TOT_010001070 2e1437b9cc074de019d5d3ea9e3c84be 660 Pfam PF14733 AP2-coincident C-terminal 564 647 6.1E-14 T 01-11-2018 IPR028078 AP2-coincident, C-terminal domain TOT_010001070 2e1437b9cc074de019d5d3ea9e3c84be 660 Pfam PF00847 AP2 domain 340 391 2.2E-11 T 01-11-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 TOT_020000808 239e153c09ce69ba806315f791396958 112 SUPERFAMILY SSF57716 21 101 2.28E-7 T 01-11-2018 TOT_030000749 53db875a04a36248e43ad03a310ca12c 364 Pfam PF04385 Domain of unknown function, DUF529 145 194 1.0E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_030000749 53db875a04a36248e43ad03a310ca12c 364 Pfam PF04385 Domain of unknown function, DUF529 46 95 8.3E-7 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_030000749 53db875a04a36248e43ad03a310ca12c 364 Pfam PF04385 Domain of unknown function, DUF529 246 301 4.2E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000885 a82b23655b134758900c0f13a4664a4b 334 Pfam PF07985 SRR1 87 141 9.2E-7 T 01-11-2018 IPR012942 SRR1-like domain TOT_020000841 398f7daff618ed61021be068780300e4 1757 Pfam PF04385 Domain of unknown function, DUF529 79 149 2.7E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000841 398f7daff618ed61021be068780300e4 1757 Pfam PF04385 Domain of unknown function, DUF529 255 304 2.0E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000841 398f7daff618ed61021be068780300e4 1757 Pfam PF04385 Domain of unknown function, DUF529 761 812 2.8E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000196 baed521bd93391b9f2497a71e212a0e7 935 Pfam PF01496 V-type ATPase 116kDa subunit family 28 921 1.7E-244 T 01-11-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TOT_040000196 baed521bd93391b9f2497a71e212a0e7 935 PIRSF PIRSF001293 1 932 3.3E-244 T 01-11-2018 IPR026028 ATPase, V0 complex, subunit 116kDa, eukaryotic GO:0000220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TOT_010001047 f579d1a1a19a0b3d687df4c1276f7a43 994 Pfam PF04403 Paraquat-inducible protein A 129 290 4.8E-7 T 01-11-2018 IPR007498 Intermembrane transport protein PqiA-like TOT_010000430 b346cbe9b1189bcbb6629bbf35246ca7 713 Pfam PF00847 AP2 domain 352 394 8.9E-5 T 01-11-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 TOT_040000030 929ba8cf30f6dd51dbe0cb3c378b12c0 237 Pfam PF09745 Coiled-coil domain-containing protein 55 (DUF2040) 94 211 1.7E-14 T 01-11-2018 IPR018612 Domain of unknown function DUF2040 TOT_030000642 6e844febd46b9724dd67ef0fa1cd1ca6 992 SUPERFAMILY SSF50978 223 529 1.65E-7 T 01-11-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 TOT_010001204 424ec01892322adbebb6e968ab1eca44 153 Pfam PF07047 Optic atrophy 3 protein (OPA3) 2 126 1.1E-31 T 01-11-2018 IPR010754 Optic atrophy 3-like TOT_040000021 14b328ebbd384f60f577209717446a0d 477 Pfam PF04385 Domain of unknown function, DUF529 405 465 5.8E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000021 14b328ebbd384f60f577209717446a0d 477 Pfam PF04385 Domain of unknown function, DUF529 283 365 1.5E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000048 93ca7ea988c56d82ab6383c865f245ab 577 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 225 245 - T 01-11-2018 IPR013087 Zinc finger C2H2-type GO:0003676 TOT_020000196 ab2a1169b1eb1827ae1de069c293735f 261 Pfam PF04385 Domain of unknown function, DUF529 147 217 5.3E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000602 3c0c1649d285cc6a05e21a592158991c 238 Gene3D G3DSA:3.40.50.790 164 238 4.1E-15 T 01-11-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich TOT_010000602 3c0c1649d285cc6a05e21a592158991c 238 SUPERFAMILY SSF56808 136 238 3.4E-20 T 01-11-2018 IPR023674 Ribosomal protein L1-like TOT_010000999 86af49aadc628bd7637b0bb01d469f23 283 Pfam PF02488 Merozoite Antigen 32 281 1.3E-91 T 01-11-2018 IPR003407 Merozoite antigen TOT_020000014 ad2ec9a2280567c10847d89060107cef 494 Pfam PF04385 Domain of unknown function, DUF529 389 463 4.4E-7 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000014 ad2ec9a2280567c10847d89060107cef 494 Pfam PF04385 Domain of unknown function, DUF529 156 203 3.9E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000939 680b119ecce6ff9c097b1896a77b1950 1077 Pfam PF04385 Domain of unknown function, DUF529 254 327 2.1E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000170 53826e0b254014a961c214c43c83f788 267 Pfam PF03998 Utp11 protein 12 265 3.4E-27 T 01-11-2018 IPR007144 Small-subunit processome, Utp11 GO:0006364|GO:0032040 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TOT_030000233 c8bf989a264871708da89590bf3e7b92 305 Pfam PF09468 Ydr279p protein family (RNase H2 complex component) 41 262 3.8E-19 T 01-11-2018 IPR019024 Ribonuclease H2, subunit B GO:0005634 TOT_030000842 819c0724c0caa8b506a32ecb27dbe994 388 Pfam PF04385 Domain of unknown function, DUF529 183 254 2.9E-7 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_030000842 819c0724c0caa8b506a32ecb27dbe994 388 Pfam PF04385 Domain of unknown function, DUF529 81 148 7.5E-8 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010001007 d9026986fdc117e04ef98630319e84a2 772 Gene3D G3DSA:1.25.40.790 423 576 1.5E-7 T 01-11-2018 TOT_010000409 3c4c46cacdda63008f20b216477ad0f8 441 Pfam PF12314 Inner membrane complex protein 105 177 9.7E-11 T 01-11-2018 IPR022086 Inner membrane complex protein TOT_040000796 b3caf12e5576fd0d64c13da788abb063 441 Pfam PF04385 Domain of unknown function, DUF529 147 195 1.8E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_030000100 b4f8bf5b005413fa07791f1cdd6dabd3 486 Pfam PF02517 CAAX protease self-immunity 393 476 7.1E-12 T 01-11-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 TOT_020000547 3dd3fe84b9f764c1803d07b68eb006f7 245 Pfam PF08648 Protein of unknown function (DUF1777) 67 241 3.7E-28 T 01-11-2018 IPR013957 U4/U6.U5 small nuclear ribonucleoprotein 27kDa protein GO:0008380 Reactome: R-HSA-72163 TOT_010000627 4e292553493cf06042cdb258f9579f77 727 Pfam PF01585 G-patch domain 125 154 2.8E-5 T 01-11-2018 IPR000467 G-patch domain GO:0003676 TOT_040000812 aa40d38e63cb568edea45c74a822f64e 865 Pfam PF04385 Domain of unknown function, DUF529 538 570 1.5E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010001300 14754f2303dfb24d6f908b9b7e358f55 346 SUPERFAMILY SSF54791 248 319 5.26E-6 T 01-11-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TOT_040000478 abc3a1c7d8f63df42ee8d95fe976f2a0 815 Pfam PF04385 Domain of unknown function, DUF529 153 225 1.8E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000478 abc3a1c7d8f63df42ee8d95fe976f2a0 815 Pfam PF04385 Domain of unknown function, DUF529 388 457 1.2E-4 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000478 abc3a1c7d8f63df42ee8d95fe976f2a0 815 Pfam PF04385 Domain of unknown function, DUF529 271 329 1.5E-8 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000924 fa832c49c83d98cf188a9c83538b3c49 330 Pfam PF04385 Domain of unknown function, DUF529 27 93 1.7E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_010000924 fa832c49c83d98cf188a9c83538b3c49 330 Pfam PF04385 Domain of unknown function, DUF529 194 249 3.8E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000968 e5d87074994863ab54e7db68720e4cea 521 Pfam PF00847 AP2 domain 423 476 4.5E-7 T 01-11-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 TOT_030000274 ae29fb35681c21ca915d9abbdbb0abab 290 Pfam PF01529 DHHC palmitoyltransferase 105 234 1.8E-31 T 01-11-2018 IPR001594 Palmitoyltransferase, DHHC domain TOT_030000036 eb5f867bd4dd833b3d46b13b490dbdd6 1696 Pfam PF04385 Domain of unknown function, DUF529 345 395 7.3E-5 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_030000036 eb5f867bd4dd833b3d46b13b490dbdd6 1696 Pfam PF04385 Domain of unknown function, DUF529 227 299 3.4E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_020000198 2bf31f02373739b108c01fbaa8d7acfa 269 Pfam PF04385 Domain of unknown function, DUF529 149 225 2.0E-6 T 01-11-2018 IPR007480 Protein of unknown function DUF529 TOT_040000722 0597d64c8ca8fd5007acb4dca4ce8572 1438 Pfam PF00847 AP2 domain 1338 1388 3.8E-15 T 01-11-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 TOT_010000147 ecc9bc753eea65f7a5b29cf6379aef4e 726 Pfam PF04006 Mpp10 protein 455 697 3.4E-17 T 01-11-2018 IPR012173 U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 GO:0005634|GO:0005732|GO:0006364|GO:0034457 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TOT_010000147 ecc9bc753eea65f7a5b29cf6379aef4e 726 Pfam PF04006 Mpp10 protein 82 416 2.8E-15 T 01-11-2018 IPR012173 U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 GO:0005634|GO:0005732|GO:0006364|GO:0034457 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TOT_030000732 19a180fbf3454b3983acbcdc9972c2be 1039 Pfam PF06762 Lipase maturation factor 170 943 5.5E-86 T 01-11-2018 IPR009613 Lipase maturation factor Reactome: R-HSA-8963889