locus-tag	class	description
TherJR_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
TherJR_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
TherJR_0004	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
TherJR_0008	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TherJR_0009	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TherJR_0010	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
TherJR_0011	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
TherJR_0012	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
TherJR_0014	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
TherJR_0015	ENOG4108Z6B	deaminase
TherJR_0016	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
TherJR_0017	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
TherJR_0018	ENOG4105DVE	abc transporter atp-binding protein
TherJR_0020	ENOG4105CN1	protease
TherJR_0022	ENOG4108KN0	Choline kinase
TherJR_0024	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
TherJR_0025	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
TherJR_0027	ENOG4108Q52	Methyltransferase cognate corrinoid protein
TherJR_0031	ENOG4108IA2	Sodium pantothenate symporter
TherJR_0032	ENOG4108VJN	May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place
TherJR_0034	ENOG4105CPD	ethanolamine ammonia-lyase
TherJR_0035	ENOG4107FQ9	ethanolamine ammonia-lyase
TherJR_0036	ENOG4105DYY	Reactivating factor for ethanolamine ammonia lyase
TherJR_0037	ENOG4106D67	ethanolamine utilization protein
TherJR_0038	ENOG4108PFF	ethanolamine utilization cobalamin adenosyltransferase
TherJR_0039	ENOG4107RWI	ethanolamine utilization protein eutJ
TherJR_0041	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
TherJR_0042	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
TherJR_0044	ENOG4105NDK	ethanolamine utilization protein
TherJR_0045	ENOG4105KNY	Microcompartments protein
TherJR_0046	ENOG4105KNY	Microcompartments protein
TherJR_0047	ENOG4108EKI	Dehydrogenase
TherJR_0048	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
TherJR_0050	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
TherJR_0052	ENOG4108Q52	Methyltransferase cognate corrinoid protein
TherJR_0054	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
TherJR_0058	ENOG4108Q52	Methyltransferase cognate corrinoid protein
TherJR_0059	ENOG4107VP5	methyltetrahydrofolate corrinoid iron-sulfur protein methyltransferase
TherJR_0060	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
TherJR_0063	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
TherJR_0064	ENOG4107XKF	NMT1 THI5 Like Domain Protein
TherJR_0066	ENOG4105FJ0	thiamine
TherJR_0068	ENOG4105C6E	dna polymerase iii
TherJR_0069	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
TherJR_0070	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
TherJR_0071	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
TherJR_0082	ENOG4105E4C	Lytic transglycosylase catalytic
TherJR_0084	ENOG4105CXN	decarboxylase
TherJR_0085	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
TherJR_0087	ENOG4105FA2	dna polymerase iii
TherJR_0088	ENOG4105MA4	psp1 domain protein
TherJR_0089	ENOG4105QD5	Involved in initiation control of chromosome replication (By similarity)
TherJR_0090	ENOG41060K3	Methyltransferase
TherJR_0091	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
TherJR_0092	ENOG4105KRN	Transcriptional regulator, abrb family
TherJR_0094	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
TherJR_0095	ENOG4105F8V	Hydrolase, tatD family
TherJR_0101	ENOG41069ER	domain protein
TherJR_0102	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
TherJR_0104	ENOG4105XFA	sporulation peptidase YabG
TherJR_0105	ENOG4105CMR	udp-glucose 4-epimerase
TherJR_0109	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
TherJR_0110	ENOG4108V3W	Chemotaxis protein, CheW
TherJR_0111	ENOG4105CBS	Chea signal transduction histidine kinase
TherJR_0112	ENOG4107YTP	response regulator receiver protein
TherJR_0113	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
TherJR_0116	ENOG4107SDU	Methyl-accepting chemotaxis
TherJR_0123	ENOG4105C8Q	Methyl-accepting chemotaxis
TherJR_0124	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
TherJR_0125	ENOG4105DDG	Cyanophycinase
TherJR_0127	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
TherJR_0128	ENOG4105DRR	Transcriptional regulator, GntR family
TherJR_0130	ENOG4105K4W	Could be involved in septation (By similarity)
TherJR_0131	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
TherJR_0132	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
TherJR_0133	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
TherJR_0139	ENOG4108UIH	futalosine nucleosidase
TherJR_0140	ENOG4105E63	Pfam:DUF178
TherJR_0148	ENOG4105GXZ	Ferredoxin-type protein NapH
TherJR_0150	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TherJR_0152	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
TherJR_0154	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TherJR_0156	ENOG4105HEE	Binding Domain protein
TherJR_0157	ENOG4105XEA	Tetr family transcriptional regulator
TherJR_0158	ENOG4105DR5	peptidase
TherJR_0162	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
TherJR_0165	ENOG4105Q2H	domain protein
TherJR_0171	ENOG4107SDU	Methyl-accepting chemotaxis
TherJR_0173	ENOG4105C0H	protease
TherJR_0175	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
TherJR_0176	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
TherJR_0178	ENOG4108JA2	transcriptioN-repair coupling factor
TherJR_0179	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
TherJR_0180	ENOG4108M14	stage v sporulation protein t
TherJR_0181	ENOG4105CKP	Polysaccharide Biosynthesis Protein
TherJR_0182	ENOG4108IY2	MazG family
TherJR_0183	ENOG4105K70	DNA-binding protein
TherJR_0184	ENOG4105C8Q	Methyl-accepting chemotaxis
TherJR_0185	ENOG41082I2	s4 domain protein
TherJR_0186	ENOG4105JFG	SpoIID LytB domain protein
TherJR_0187	ENOG4105VYY	sporulation protein yabp
TherJR_0191	ENOG41060GV	RNA binding s1 domain protein
TherJR_0193	ENOG4107Z3H	Transcriptional regulator, TetR family
TherJR_0196	ENOG4107R33	ppx gppa phosphatase
TherJR_0198	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
TherJR_0204	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
TherJR_0205	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TherJR_0206	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
TherJR_0208	ENOG4105CKU	formyltetrahydrofolate synthetase
TherJR_0209	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
TherJR_0210	ENOG4105EEI	dihydropteroate synthase
TherJR_0211	ENOG4105KRF	dihydroneopterin aldolase
TherJR_0212	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TherJR_0213	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
TherJR_0214	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
TherJR_0215	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
TherJR_0216	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
TherJR_0217	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
TherJR_0218	ENOG4108IYU	L-aspartate oxidase
TherJR_0219	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
TherJR_0224	ENOG4108W5Z	CheC domain protein
TherJR_0225	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
TherJR_0226	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
TherJR_0229	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
TherJR_0230	ENOG4105CRK	lysyL-tRNA synthetase
TherJR_0234	ENOG4107EFR	Flavocytochrome c
TherJR_0235	ENOG4107YHD	transcriptional regulator
TherJR_0236	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
TherJR_0241	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
TherJR_0242	ENOG41066A3	ATP guanido phosphotransferase
TherJR_0245	ENOG4105EKQ	RNA-directed DNA polymerase
TherJR_0247	ENOG4107SGM	protein serine threonine phosphatase
TherJR_0248	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
TherJR_0249	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
TherJR_0251	ENOG4108VJ1	Transcriptional regulator (CarD family
TherJR_0252	ENOG4105CTP	PilT protein domain protein
TherJR_0253	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
TherJR_0254	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
TherJR_0257	ENOG4105E3S	small subunit
TherJR_0258	ENOG4105DPX	Hydrogenase, large subunit
TherJR_0260	ENOG4108USZ	hydrogenase
TherJR_0261	ENOG41067SE	Tetr family transcriptional regulator
TherJR_0263	ENOG4107KET	secretion protein, HlyD family
TherJR_0266	ENOG4105PTM	secreted protein
TherJR_0268	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
TherJR_0269	ENOG4105D7W	serine acetyltransferase
TherJR_0270	ENOG4105C8N	cysteinyl-tRNA synthetase
TherJR_0271	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
TherJR_0273	ENOG4105C2N	RNA methyltransferase TrmH family group 3
TherJR_0274	ENOG4105M0M	Tetracycline resistance protein
TherJR_0275	ENOG4105QIV	RNA polymerase
TherJR_0276	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TherJR_0280	ENOG4105WDJ	50S ribosomal protein L33
TherJR_0282	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
TherJR_0283	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
TherJR_0284	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
TherJR_0285	ENOG4108VZM	50s ribosomal protein L10
TherJR_0286	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
TherJR_0288	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TherJR_0289	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TherJR_0290	ENOG4105XPM	ribosomal protein
TherJR_0291	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
TherJR_0292	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
TherJR_0293	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TherJR_0294	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TherJR_0295	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
TherJR_0296	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
TherJR_0297	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
TherJR_0298	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
TherJR_0299	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TherJR_0300	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
TherJR_0301	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
TherJR_0302	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
TherJR_0303	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
TherJR_0304	ENOG41082SA	50s ribosomal protein l29
TherJR_0305	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
TherJR_0306	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
TherJR_0307	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
TherJR_0309	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
TherJR_0310	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
TherJR_0311	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
TherJR_0312	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
TherJR_0313	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
TherJR_0314	ENOG4105VPB	50S ribosomal protein L30
TherJR_0315	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
TherJR_0316	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
TherJR_0317	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
TherJR_0319	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
TherJR_0320	ENOG41067V7	50S ribosomal protein L36
TherJR_0321	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TherJR_0322	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
TherJR_0323	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
TherJR_0324	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TherJR_0325	ENOG4108ZT0	50S ribosomal protein l17
TherJR_0327	ENOG4108JJB	ABC transporter
TherJR_0328	ENOG4108JJB	ABC transporter
TherJR_0329	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
TherJR_0330	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
TherJR_0331	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
TherJR_0336	ENOG4105NBF	ammecr1 domain protein
TherJR_0341	ENOG4108Q5Y	Membrane
TherJR_0343	ENOG4105E3S	small subunit
TherJR_0344	ENOG4105DPX	Hydrogenase, large subunit
TherJR_0346	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
TherJR_0347	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
TherJR_0350	ENOG4105CAS	nag kinase
TherJR_0351	ENOG4105C8Y	Acetylornithine aminotransferase
TherJR_0352	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
TherJR_0353	ENOG4105DBV	ornithine carbamoyltransferase
TherJR_0356	ENOG4105CH7	arginosuccinase
TherJR_0358	ENOG4105CM2	brancheD-chain amino acid aminotransferase
TherJR_0359	ENOG4105C01	Dihydroxy-acid dehydratase
TherJR_0360	ENOG4105C7K	acetolactate synthase
TherJR_0362	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
TherJR_0363	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
TherJR_0364	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TherJR_0365	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TherJR_0366	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
TherJR_0367	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
TherJR_0368	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
TherJR_0370	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
TherJR_0372	ENOG4105E4C	Lytic transglycosylase catalytic
TherJR_0374	ENOG4105K67	small basic protein
TherJR_0376	ENOG4105C8B	TIGR00159 family
TherJR_0378	ENOG4105DZ0	fad dependent oxidoreductase
TherJR_0379	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
TherJR_0380	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TherJR_0401	ENOG4105RYY	domain protein
TherJR_0412	ENOG4105BZU	Histidine kinase
TherJR_0419	ENOG4105E89	ABC transporter
TherJR_0421	ENOG4108QG2	Membrane
TherJR_0422	ENOG4105E2V	Glycosyltransferase 36
TherJR_0423	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
TherJR_0424	ENOG4106TD9	Diguanylate cyclase
TherJR_0431	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
TherJR_0437	ENOG4107YU2	histidine triad (hIT) protein
TherJR_0440	ENOG4108RAC	Rubrerythrin
TherJR_0441	ENOG4105MAX	Superoxide reductase
TherJR_0452	ENOG4107RM6	sulfurtransferase
TherJR_0453	ENOG4105C2C	drug resistance transporter, Bcr CflA
TherJR_0454	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
TherJR_0455	ENOG4105PGM	cation diffusion facilitator family transporter
TherJR_0465	ENOG410904A	RNA polymerase
TherJR_0471	ENOG41082YX	Transcriptional regulator, arsr family
TherJR_0472	ENOG4105D6J	arsenicaL-resistance protein
TherJR_0474	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
TherJR_0476	ENOG4105DQR	SNARE associated Golgi
TherJR_0482	ENOG4105CJR	Integral membrane protein (MviN
TherJR_0483	ENOG4105EMN	RNA polymerase sigma factor
TherJR_0486	ENOG4107ZTW	SNARE associated Golgi
TherJR_0494	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
TherJR_0495	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
TherJR_0497	ENOG4105KHC	sulfurtransferase
TherJR_0498	ENOG4105CKK	Glycosyl transferase, family 2
TherJR_0500	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
TherJR_0503	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
TherJR_0505	ENOG4105DUM	transcriptional regulator, lysR family
TherJR_0506	ENOG41066VF	YeeE YedE family protein
TherJR_0508	ENOG41066VF	YeeE YedE family protein
TherJR_0515	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TherJR_0516	ENOG4105BZU	Histidine kinase
TherJR_0518	ENOG410841Q	phosphoesterase PA-phosphatase related protein
TherJR_0520	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TherJR_0522	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TherJR_0525	ENOG4105CYC	Transferase
TherJR_0526	ENOG4105DUM	transcriptional regulator, lysR family
TherJR_0528	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
TherJR_0537	ENOG4105C7H	Helicase, RecD TraA family
TherJR_0542	ENOG4108IG5	Transcriptional regulator
TherJR_0543	ENOG4105WH1	Two component transcriptional regulator luxr family
TherJR_0544	ENOG4105DF6	Fe-S oxidoreductase
TherJR_0545	ENOG4105EPH	radical SAM domain protein
TherJR_0547	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
TherJR_0548	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
TherJR_0549	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
TherJR_0550	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
TherJR_0551	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
TherJR_0552	ENOG4105ETS	cytosine purines uracil thiamine allantoin
TherJR_0554	ENOG4105D0M	Protease HtpX homolog
TherJR_0555	ENOG4106S2D	Transcriptional regulator
TherJR_0556	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TherJR_0562	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TherJR_0569	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TherJR_0579	ENOG4105C7Z	Conserved Protein
TherJR_0581	ENOG4107RDB	Major Facilitator
TherJR_0585	ENOG4105WMR	Protein CrcB homolog
TherJR_0586	ENOG4105WMR	Protein CrcB homolog
TherJR_0587	ENOG4105KJJ	Uncharacterized ACR, COG1993
TherJR_0590	ENOG4105C0D	helicase
TherJR_0597	ENOG41062MS	nucleotidyltransferase substrate binding protein
TherJR_0600	ENOG4107UWC	ABC, transporter
TherJR_0601	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
TherJR_0605	ENOG4108YZ9	Urea amidohydrolase subunit gamma
TherJR_0606	ENOG4105KI2	Urea amidohydrolase subunit beta
TherJR_0607	ENOG4105CQM	Urea amidohydrolase subunit alpha
TherJR_0609	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
TherJR_0610	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
TherJR_0611	ENOG4105ICD	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
TherJR_0612	ENOG4108UQ5	membrane protein YcdZ
TherJR_0613	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
TherJR_0614	ENOG4105C2F	Histidine kinase
TherJR_0615	ENOG4108VAC	response regulator
TherJR_0616	ENOG4105KNY	Microcompartments protein
TherJR_0617	ENOG4105EHR	propanediol utilization protein pduB
TherJR_0619	ENOG4105YCI	dehydratase medium subunit
TherJR_0620	ENOG4108ZFT	Dehydratase small subunit
TherJR_0621	ENOG41084PW	diol glycerol dehydratase reactivating factor large subunit
TherJR_0623	ENOG4105KNY	Microcompartments protein
TherJR_0624	ENOG4105KNY	Microcompartments protein
TherJR_0625	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
TherJR_0626	ENOG4107RWI	ethanolamine utilization protein eutJ
TherJR_0630	ENOG4108EKI	Dehydrogenase
TherJR_0631	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
TherJR_0633	ENOG4105DCT	glycerol dehydrogenase
TherJR_0635	ENOG41067MG	lrgb family
TherJR_0636	ENOG4105IJJ	transcriptional regulator, crp fnr family
TherJR_0645	ENOG4105VRS	hydrolase family 18
TherJR_0648	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
TherJR_0651	ENOG4108HRK	Histidine kinase
TherJR_0652	ENOG4108NEV	two component transcriptional regulator, LytTR family
TherJR_0653	ENOG4108V3W	Chemotaxis protein, CheW
TherJR_0654	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
TherJR_0655	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
TherJR_0657	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
TherJR_0665	ENOG4105CAQ	asparagine synthetase
TherJR_0672	ENOG4107SHJ	sulfite reductase subunit b
TherJR_0675	ENOG41071TK	Uncharacterised protein family (UPF0150)
TherJR_0688	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
TherJR_0689	ENOG4108YZA	Nitrogen regulatory protein pii
TherJR_0690	ENOG4108YZA	Nitrogen regulatory protein pii
TherJR_0695	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
TherJR_0698	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
TherJR_0699	ENOG4105E0C	molybdate abc transporter
TherJR_0700	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
TherJR_0701	ENOG4107SDT	Homocitrate synthase
TherJR_0702	ENOG4105BZU	Histidine kinase
TherJR_0703	ENOG4108YZA	Nitrogen regulatory protein pii
TherJR_0706	ENOG4108YZA	Nitrogen regulatory protein pii
TherJR_0711	ENOG4105EYU	Glutamine amido-transferase
TherJR_0712	ENOG4105CBC	glutamate synthase
TherJR_0713	ENOG4108RC0	Electron transport protein
TherJR_0714	ENOG4108IFG	nitrite reductase, (NAD(P)H)
TherJR_0717	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
TherJR_0718	ENOG4108Z86	Glutamine amidotransferase
TherJR_0722	ENOG4105CI2	imidazolone-5-propionate hydrolase
TherJR_0724	ENOG4105DWF	phosphomethylpyrimidine kinase
TherJR_0725	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
TherJR_0726	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
TherJR_0727	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
TherJR_0728	ENOG4105K8N	protein family UPF0079, ATPase
TherJR_0729	ENOG41072GX	Peptidase M22 Glycoprotease
TherJR_0730	ENOG410801F	ribosomal-protein-alanine acetyltransferase
TherJR_0733	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
TherJR_0735	ENOG4105DZS	Phenylacetate-CoA ligase
TherJR_0739	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
TherJR_0740	ENOG4105GKE	subunit e
TherJR_0741	ENOG4107QIZ	NADH dehydrogenase
TherJR_0743	ENOG4108HIZ	formate dehydrogenase alpha subunit
TherJR_0744	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
TherJR_0746	ENOG4105DHT	Metal Dependent Phosphohydrolase
TherJR_0747	ENOG4108ZDA	Sporulation protein YyaC
TherJR_0749	ENOG4108ESY	Metal dependent phosphohydrolase
TherJR_0751	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
TherJR_0752	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
TherJR_0753	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
TherJR_0754	ENOG41074B2	UPF0747 protein
TherJR_0755	ENOG4108IAB	Phoh family
TherJR_0757	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
TherJR_0758	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
TherJR_0759	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TherJR_0760	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TherJR_0762	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
TherJR_0763	ENOG4108JUA	Transcriptional regulator
TherJR_0764	ENOG4105E3S	small subunit
TherJR_0765	ENOG4105DPX	Hydrogenase, large subunit
TherJR_0766	ENOG4108USZ	hydrogenase
TherJR_0767	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
TherJR_0769	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
TherJR_0771	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
TherJR_0772	ENOG4105DVI	reductase, NrfD
TherJR_0774	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
TherJR_0775	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
TherJR_0777	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TherJR_0779	ENOG4105RYY	domain protein
TherJR_0781	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
TherJR_0783	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
TherJR_0786	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
TherJR_0787	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TherJR_0789	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TherJR_0794	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TherJR_0797	ENOG4105BZU	Histidine kinase
TherJR_0798	ENOG4108MRH	transcriptional regulatory protein
TherJR_0799	ENOG4105C3U	ABC transporter
TherJR_0800	ENOG4108JQ7	(ABC) transporter
TherJR_0801	ENOG4105DEF	Extracellular solute-binding protein, family 5
TherJR_0802	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
TherJR_0803	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TherJR_0813	ENOG4108EHY	type IV secretion system
TherJR_0819	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
TherJR_0821	ENOG4105DND	Transcriptional regulator
TherJR_0822	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
TherJR_0823	ENOG4105C7N	Xanthine uracil vitamin C permease
TherJR_0824	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
TherJR_0825	ENOG4105C83	adenylosuccinate lyase
TherJR_0826	ENOG4105C8V	SAICAR synthetase
TherJR_0827	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
TherJR_0828	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
TherJR_0829	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
TherJR_0830	ENOG4105DC1	bifunctional purine biosynthesis protein purh
TherJR_0831	ENOG4105C12	Phosphoribosylglycinamide synthetase
TherJR_0832	ENOG4105KGF	protein, YerC YecD
TherJR_0833	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
TherJR_0834	ENOG4108IQ6	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
TherJR_0837	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TherJR_0838	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
TherJR_0840	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
TherJR_0841	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
TherJR_0842	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
TherJR_0843	ENOG4105C8Q	Methyl-accepting chemotaxis
TherJR_0845	ENOG4108VCT	Sulfite exporter TauE/SafE
TherJR_0848	ENOG4105C4R	Atp-dependent dna helicase
TherJR_0850	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
TherJR_0851	ENOG4105UFH	BadM Rrf2 family transcriptional regulator
TherJR_0852	ENOG4105C4M	(Ubiquinol oxidase) subunit I
TherJR_0853	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
TherJR_0854	ENOG4105KY8	Rubrerythrin
TherJR_0855	ENOG4105C0A	alcohol dehydrogenase
TherJR_0857	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TherJR_0858	ENOG4105CIZ	coA-substrate-specific enzyme activase
TherJR_0859	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
TherJR_0861	ENOG4106TNF	Periplasmic binding protein
TherJR_0862	ENOG4105E5Q	amino acid AbC transporter
TherJR_0870	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TherJR_0871	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
TherJR_0872	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TherJR_0874	ENOG4107SDT	Homocitrate synthase
TherJR_0875	ENOG4108HMX	isocitrate dehydrogenase (NADP)
TherJR_0876	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
TherJR_0878	ENOG4105UIB	(ABC) transporter
TherJR_0879	ENOG4108JQ9	ABC transporter
TherJR_0885	ENOG4107RFW	hydrolase family 57
TherJR_0890	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TherJR_0899	ENOG4105CVR	type I restriction-modification system
TherJR_0900	ENOG4105EKX	Restriction modification system DNA (Specificity
TherJR_0901	ENOG4105DZR	Type I site-specific deoxyribonuclease
TherJR_0906	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
TherJR_0909	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
TherJR_0910	ENOG4107Y70	Heat shock protein
TherJR_0911	ENOG4107YZX	Universal stress protein
TherJR_0913	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TherJR_0916	ENOG4105CW7	secretion protein, HlyD family
TherJR_0917	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TherJR_0918	ENOG41067TZ	transcriptional regulator, MarR family
TherJR_0923	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
TherJR_0924	ENOG4105DIW	FeS assembly protein SUFB
TherJR_0925	ENOG4105CFG	Acts as a chaperone (By similarity)
TherJR_0928	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TherJR_0929	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
TherJR_0931	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
TherJR_0932	ENOG4108SGK	Tetr family transcriptional regulator
TherJR_0934	ENOG4107QID	Threonine synthase
TherJR_0937	ENOG4105CVN	desaturase
TherJR_0941	ENOG4107SHJ	sulfite reductase subunit b
TherJR_0942	ENOG4108IEG	Formate dehydrogenase Alpha subunit
TherJR_0943	ENOG4105DUM	transcriptional regulator, lysR family
TherJR_0944	ENOG4108S4H	thioesterase Superfamily protein
TherJR_0947	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
TherJR_0948	ENOG4107STQ	Multicopper oxidase
TherJR_0949	ENOG4108V9Q	carbonic anhydrase
TherJR_0950	ENOG4105EMN	RNA polymerase sigma factor
TherJR_0954	ENOG4107TVC	Glycosyl transferase, family 2
TherJR_0955	ENOG4107TVC	Glycosyl transferase, family 2
TherJR_0956	ENOG4107TVC	Glycosyl transferase, family 2
TherJR_0958	ENOG4108MIC	Mg-protoporphyrin IX methyl transferase
TherJR_0960	ENOG4107TVC	Glycosyl transferase, family 2
TherJR_0964	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
TherJR_0966	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
TherJR_0967	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
TherJR_0968	ENOG4108J59	Extracellular solute-binding protein, family 5
TherJR_0969	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
TherJR_0970	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TherJR_0971	ENOG4105C3U	ABC transporter
TherJR_0972	ENOG4108JQ7	(ABC) transporter
TherJR_0978	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
TherJR_0983	ENOG4108Q52	Methyltransferase cognate corrinoid protein
TherJR_0984	ENOG4108Q52	Methyltransferase cognate corrinoid protein
TherJR_0989	ENOG4105CKI	cobalamin synthesis protein
TherJR_0991	ENOG4105CBC	glutamate synthase
TherJR_0994	ENOG4105BZU	Histidine kinase
TherJR_0997	ENOG4105BZU	Histidine kinase
TherJR_1002	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
TherJR_1003	ENOG4108IY8	ABC, transporter
TherJR_1005	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
TherJR_1006	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
TherJR_1014	ENOG4108UB4	uncharacterized protein ygjQ
TherJR_1015	ENOG4107QHI	-hydrogenase
TherJR_1016	ENOG4107QIZ	NADH dehydrogenase
TherJR_1017	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
TherJR_1018	ENOG41065RQ	ADP-ribosylation crystallin J1
TherJR_1027	ENOG4105CRE	cytochrome C
TherJR_1036	ENOG4105C0B	DNA polymerase III (alpha subunit)
TherJR_1040	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
TherJR_1041	ENOG4105FCD	Major Facilitator
TherJR_1043	ENOG4105CUW	cytochrome C-TYPE protein
TherJR_1046	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TherJR_1050	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
TherJR_1056	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
TherJR_1057	ENOG4105CYW	agmatinase
TherJR_1060	ENOG4105WJF	
TherJR_1061	ENOG4108SHJ	s-layer protein
TherJR_1065	ENOG4108I5C	dEAD DEAH box helicase
TherJR_1066	ENOG4108I5C	dEAD DEAH box helicase
TherJR_1070	ENOG4105C0D	helicase
TherJR_1080	ENOG4105ESI	atpase involved in dna repair
TherJR_1081	ENOG4105CB5	ATP-dependent DNA helicase recG
TherJR_1084	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
TherJR_1090	ENOG4108TVJ	Nitroreductase
TherJR_1091	ENOG4105EN6	Membrane
TherJR_1092	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TherJR_1093	ENOG4105C3U	ABC transporter
TherJR_1094	ENOG4108JQ7	(ABC) transporter
TherJR_1095	ENOG4105DEF	Extracellular solute-binding protein, family 5
TherJR_1096	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
TherJR_1097	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TherJR_1101	ENOG410839P	
TherJR_1103	ENOG410839P	
TherJR_1104	ENOG410839P	
TherJR_1108	ENOG4105CJ1	ABC, transporter
TherJR_1111	ENOG4108EKI	Dehydrogenase
TherJR_1115	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
TherJR_1118	ENOG4108W6G	cytochrome C
TherJR_1126	ENOG4105CRE	cytochrome C
TherJR_1127	ENOG4105EPH	radical SAM domain protein
TherJR_1131	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
TherJR_1132	ENOG4105CRE	cytochrome C
TherJR_1133	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
TherJR_1134	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
TherJR_1135	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
TherJR_1140	ENOG4108UMR	transcriptional regulator AsnC family
TherJR_1142	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
TherJR_1144	ENOG4105BZU	Histidine kinase
TherJR_1145	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
TherJR_1147	ENOG4105CPI	Metal Dependent Phosphohydrolase
TherJR_1153	ENOG4108DWA	Nad synthetase
TherJR_1156	ENOG41080XS	Cobyrinic acid ac-diamide synthase
TherJR_1157	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
TherJR_1158	ENOG4105E8X	CO dehydrogenase acetyl-CoA synthase complex beta subunit
TherJR_1159	ENOG4105EYX	Acetyl-CoA decarbonylase synthase complex subunit gamma
TherJR_1160	ENOG4106HYN	CO dehydrogenase acetyl-CoA synthase delta subunit
TherJR_1161	ENOG4107VP5	methyltetrahydrofolate corrinoid iron-sulfur protein methyltransferase
TherJR_1170	ENOG41069DP	small acid-soluble spore protein
TherJR_1171	ENOG4107T5V	SNARE associated Golgi
TherJR_1176	ENOG4105CPF	Cell wall formation (By similarity)
TherJR_1177	ENOG4105CDY	transcriptional regulatory protein
TherJR_1180	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
TherJR_1181	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
TherJR_1182	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
TherJR_1183	ENOG4105WPN	DNA integration recombination invertion protein
TherJR_1185	ENOG4108WZW	RNA polymerase sigma
TherJR_1186	ENOG4105WJF	
TherJR_1187	ENOG4105JFG	SpoIID LytB domain protein
TherJR_1189	ENOG4108IPJ	Membrane
TherJR_1190	ENOG4105SX7	Transporter
TherJR_1191	ENOG4106PMH	Extracellular solute-binding protein family 3
TherJR_1192	ENOG4105EAD	ABC transporter
TherJR_1194	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
TherJR_1195	ENOG4105BZU	Histidine kinase
TherJR_1196	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
TherJR_1198	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
TherJR_1200	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
TherJR_1203	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TherJR_1204	ENOG4107SBW	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TherJR_1205	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
TherJR_1206	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
TherJR_1207	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
TherJR_1208	ENOG4105C5X	domain protein
TherJR_1211	ENOG4105DB7	PHP domain protein
TherJR_1212	ENOG4107ZYR	domain protein
TherJR_1216	ENOG4106678	morphogenetic protein associated with SpoVID
TherJR_1220	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TherJR_1221	ENOG4105BZU	Histidine kinase
TherJR_1222	ENOG4105DF6	Fe-S oxidoreductase
TherJR_1232	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TherJR_1233	ENOG4105C3U	ABC transporter
TherJR_1234	ENOG4108JQ7	(ABC) transporter
TherJR_1235	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TherJR_1237	ENOG4107RBS	Methyltransferase
TherJR_1241	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TherJR_1242	ENOG4108JQ6	ABC transporter
TherJR_1243	ENOG4108BSC	Methyltransferase
TherJR_1246	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
TherJR_1255	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
TherJR_1262	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
TherJR_1264	ENOG4108V4M	Cobalt abc transporter
TherJR_1265	ENOG4108JJB	ABC transporter
TherJR_1266	ENOG4108JTQ	reductase
TherJR_1268	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
TherJR_1270	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
TherJR_1274	ENOG4105D7N	magnesium and cobalt transport protein CorA
TherJR_1277	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
TherJR_1278	ENOG4105KC9	Modulates RecA activity (By similarity)
TherJR_1279	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
TherJR_1281	ENOG4105D48	metallophosphoesterase
TherJR_1282	ENOG4105MCT	stage V sporulation protein S
TherJR_1283	ENOG4108IGT	Dipeptidase
TherJR_1284	ENOG4105CHM	Aminotransferase
TherJR_1286	ENOG4105K4H	Nlp p60 protein
TherJR_1291	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
TherJR_1298	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TherJR_1299	ENOG4105C19	ABC transporter
TherJR_1302	ENOG4105CQS	hydrogenase expression formation protein HypD
TherJR_1303	ENOG4105C45	hydrogenase expression formation protein (HypE)
TherJR_1308	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
TherJR_1309	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
TherJR_1310	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
TherJR_1311	ENOG4105JZC	GHMP kinase
TherJR_1312	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TherJR_1313	ENOG4108TGR	phosphatase
TherJR_1315	ENOG4105CPN	adenine deaminase
TherJR_1319	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TherJR_1321	ENOG4106JDQ	ATP-dependent Clp protease, Hsp 100, ATP-binding subunit ClpB
TherJR_1325	ENOG4105CE1	Ferrous iron transport protein b
TherJR_1326	ENOG4105I3K	Ferric uptake regulator, Fur family
TherJR_1329	ENOG4108VCT	Sulfite exporter TauE/SafE
TherJR_1330	ENOG4108VCT	Sulfite exporter TauE/SafE
TherJR_1334	ENOG4105CNI	cell division protein FtsW
TherJR_1336	ENOG4108YZ4	nudix hydrolase
TherJR_1339	ENOG4105XEW	small acid-soluble spore protein
TherJR_1341	ENOG4105Z5G	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
TherJR_1342	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
TherJR_1343	ENOG4105BZU	Histidine kinase
TherJR_1349	ENOG4105BZU	Histidine kinase
TherJR_1351	ENOG4105DYB	Isoaspartyl dipeptidase
TherJR_1355	ENOG4108VMM	UPF0756 membrane protein
TherJR_1356	ENOG4105CE9	30S ribosomal protein S2
TherJR_1357	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
TherJR_1358	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
TherJR_1359	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
TherJR_1363	ENOG4105KNE	Phosphatidate cytidylyltransferase
TherJR_1364	ENOG4108REF	Sporulation integral membrane protein ytvi
TherJR_1365	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
TherJR_1366	ENOG4105DZP	Membrane-associated zinc metalloprotease
TherJR_1367	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
TherJR_1368	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
TherJR_1370	ENOG4105KT7	mgtC SapB transporter
TherJR_1373	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
TherJR_1374	ENOG4105CHV	Transcription elongation factor NusA
TherJR_1375	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
TherJR_1377	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
TherJR_1377	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
TherJR_1378	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
TherJR_1379	ENOG4105SFS	phosphoesterase RecJ domain protein
TherJR_1380	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
TherJR_1381	ENOG4105DTN	riboflavin biosynthesis protein ribF
TherJR_1384	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
TherJR_1385	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TherJR_1386	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
TherJR_1387	ENOG4105F0V	Cell wall hydrolase
TherJR_1388	ENOG4105K4H	Nlp p60 protein
TherJR_1389	ENOG4105VRS	hydrolase family 18
TherJR_1391	ENOG4105DZ1	carboxypeptidase
TherJR_1392	ENOG4105C1V	Peptidase, M16
TherJR_1393	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
TherJR_1396	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
TherJR_1397	ENOG4105E35	Dipicolinate synthase subunit A
TherJR_1398	ENOG4108S0H	Dipicolinic acid synthetase, b subunit
TherJR_1399	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
TherJR_1401	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
TherJR_1402	ENOG4105CN5	Metallo-Beta-Lactamase
TherJR_1403	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
TherJR_1405	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
TherJR_1406	ENOG4105CNU	cell division protein FtsK
TherJR_1407	ENOG4107TFB	basic membrane
TherJR_1411	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
TherJR_1412	ENOG4105E0M	Sulfatase
TherJR_1414	ENOG4108K88	Membrane
TherJR_1417	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
TherJR_1427	ENOG4105CRE	cytochrome C
TherJR_1429	ENOG4108VPT	UPF0234 protein
TherJR_1433	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
TherJR_1434	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
TherJR_1436	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TherJR_1437	ENOG4105CEV	competence damage-inducible protein
TherJR_1439	ENOG4105C1J	atp-dependent rna helicase
TherJR_1440	ENOG4105CPI	Metal Dependent Phosphohydrolase
TherJR_1441	ENOG4105WCA	Ferredoxin
TherJR_1442	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
TherJR_1443	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
TherJR_1446	ENOG4105CJ1	ABC, transporter
TherJR_1448	ENOG4105EPR	degv family
TherJR_1449	ENOG4107RZH	Nitrite and sulphite reductase 4Fe-4S region
TherJR_1462	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TherJR_1469	ENOG4108N5B	2-phosphosulfolactate phosphatase
TherJR_1471	ENOG4107RIQ	Sulfate adenylate transferase
TherJR_1474	ENOG4107UWC	ABC, transporter
TherJR_1478	ENOG4107RCC	Major Facilitator Superfamily
TherJR_1483	ENOG4105DU1	integral membrane protein, terc
TherJR_1485	ENOG4108QY0	Membrane
TherJR_1487	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TherJR_1488	ENOG4105WZB	UPF0342 protein
TherJR_1489	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
TherJR_1491	ENOG4105DGU	Histone deacetylase
TherJR_1492	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
TherJR_1493	ENOG4107YX5	Pfam:DUF548
TherJR_1494	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
TherJR_1495	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
TherJR_1496	ENOG4105K70	DNA-binding protein
TherJR_1497	ENOG4106F1P	AAA ATPase, central domain protein
TherJR_1498	ENOG4105CXI	aluminum resistance protein
TherJR_1499	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TherJR_1505	ENOG4107GFK	fumarate
TherJR_1506	ENOG4105C6K	Malic enzyme
TherJR_1512	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TherJR_1514	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
TherJR_1515	ENOG4107PHP	CheC --inhibitor of MCP methylation
TherJR_1516	ENOG4108V3W	Chemotaxis protein, CheW
TherJR_1517	ENOG4105CBS	Chea signal transduction histidine kinase
TherJR_1518	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
TherJR_1521	ENOG4105FZW	flagellar biosynthesis regulator FlhF
TherJR_1522	ENOG4105D7B	Flagellar biosynthesis protein flha
TherJR_1523	ENOG4105D00	flagellar biosynthetic protein flhB
TherJR_1524	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
TherJR_1525	ENOG4105VS8	Flagellar biosynthetic protein fliq
TherJR_1526	ENOG4105CN7	Flagellar biosynthetic protein FliP
TherJR_1528	ENOG4107YTP	response regulator receiver protein
TherJR_1529	ENOG4105DD5	Flagellar motor switch protein
TherJR_1530	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
TherJR_1532	ENOG41068WV	flagellar FlbD family protein
TherJR_1533	ENOG4105BZE	flagellar hook protein, FlgE
TherJR_1535	ENOG410822I	Flagellar hook capping protein
TherJR_1540	ENOG4105W2B	Flagellar assembly protein
TherJR_1541	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
TherJR_1542	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
TherJR_1543	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
TherJR_1544	ENOG4108ZC9	flagellar basal-body rod protein flgc
TherJR_1545	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
TherJR_1547	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
TherJR_1548	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
TherJR_1549	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TherJR_1550	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
TherJR_1551	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
TherJR_1553	ENOG4105DQE	DNA ligase
TherJR_1554	ENOG4108J9Q	DNA ligase
TherJR_1555	ENOG4105FDF	Could be involved in DNA repair (By similarity)
TherJR_1559	ENOG4105F0V	Cell wall hydrolase
TherJR_1561	ENOG410667J	hydrolase
TherJR_1562	ENOG41081F0	Precorrin-8x methylmutase
TherJR_1563	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
TherJR_1565	ENOG4105E4R	Precorrin-3B C17-methyltransferase
TherJR_1566	ENOG4108P62	biosynthesis protein (CbiG)
TherJR_1567	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
TherJR_1568	ENOG4105DVK	Precorrin-2 c20-methyltransferase
TherJR_1569	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
TherJR_1571	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
TherJR_1574	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TherJR_1576	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
TherJR_1579	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
TherJR_1580	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
TherJR_1581	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
TherJR_1583	ENOG4105C0H	protease
TherJR_1587	ENOG4105S2F	
TherJR_1590	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
TherJR_1591	ENOG4105F6E	Acyl-transferase
TherJR_1592	ENOG4105CAT	Cytidine monophosphate kinase
TherJR_1595	ENOG4105C8Q	Methyl-accepting chemotaxis
TherJR_1596	ENOG4108V3W	Chemotaxis protein, CheW
TherJR_1597	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
TherJR_1599	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
TherJR_1600	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
TherJR_1602	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
TherJR_1603	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
TherJR_1604	ENOG4105DK0	Indole-3-glycerol phosphate synthase
TherJR_1605	ENOG4108I0Q	anthranilate phosphoribosyltransferase
TherJR_1606	ENOG4105DDQ	anthranilate synthase
TherJR_1607	ENOG4105CRQ	synthase (Component I)
TherJR_1608	ENOG4105KHN	chorismate mutase
TherJR_1611	ENOG4105CBX	hi0933 family
TherJR_1612	ENOG41067MG	lrgb family
TherJR_1613	ENOG4105VAW	lrga family
TherJR_1615	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
TherJR_1623	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
TherJR_1627	ENOG4105FE9	pseudouridine synthase
TherJR_1629	ENOG4108JIC	nucleoside recognition domain protein
TherJR_1630	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
TherJR_1631	ENOG4105KBJ	sporulation protein ytfj
TherJR_1634	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
TherJR_1636	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
TherJR_1637	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
TherJR_1638	ENOG4105C31	Tryptophanyl-tRNA synthetase
TherJR_1639	ENOG4108Z4T	Peptidase M50
TherJR_1640	ENOG4105DJ0	Poly(A) Polymerase
TherJR_1641	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
TherJR_1642	ENOG4105K8R	UPF0145 protein
TherJR_1643	ENOG4105K4I	Scp-like extracellular
TherJR_1645	ENOG4105M6F	mutator MutT protein
TherJR_1647	ENOG4105CIZ	coA-substrate-specific enzyme activase
TherJR_1651	ENOG4105G6R	Stage v sporulation protein ae
TherJR_1653	ENOG4105CZ3	stage V sporulation protein ad
TherJR_1654	ENOG41090VF	Stage v sporulation protein ac
TherJR_1656	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TherJR_1657	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
TherJR_1658	ENOG41082AN	stage II sporulation protein
TherJR_1659	ENOG4105DZ1	carboxypeptidase
TherJR_1660	ENOG4105C0X	amino acid
TherJR_1664	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
TherJR_1665	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
TherJR_1666	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TherJR_1673	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
TherJR_1681	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
TherJR_1683	ENOG4107RE7	phosphate butyryltransferase
TherJR_1684	ENOG4108JUB	Transcriptional regulator
TherJR_1689	ENOG4107QQR	Sporulation
TherJR_1690	ENOG4105S1Z	Stage IV sporulation protein B
TherJR_1691	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
TherJR_1694	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
TherJR_1698	ENOG4105DX0	Hemolysin A
TherJR_1699	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
TherJR_1701	ENOG4105CTB	Polyprenyl synthetase
TherJR_1702	ENOG41084YM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
TherJR_1703	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
TherJR_1704	ENOG4105C6T	cysteine synthase
TherJR_1706	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
TherJR_1707	ENOG4105BZ8	glutamate synthase
TherJR_1708	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
TherJR_1709	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
TherJR_1710	ENOG4106678	morphogenetic protein associated with SpoVID
TherJR_1712	ENOG41076HS	cation diffusion facilitator family transporter
TherJR_1714	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TherJR_1715	ENOG4105M7K	Involved in the transcription termination process (By similarity)
TherJR_1718	ENOG4108ZSR	alkaline shock protein
TherJR_1719	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
TherJR_1720	ENOG4107QSA	Oxaloacetate decarboxylase
TherJR_1723	ENOG410644B	Stage III sporulation protein af
TherJR_1725	ENOG4105KQ4	Stage iii sporulation protein ad
TherJR_1726	ENOG4108CQH	stage III sporulation protein AC
TherJR_1727	ENOG4105KR5	Stage iii sporulation protein
TherJR_1728	ENOG4105CD2	stage iii sporulation protein aa
TherJR_1729	ENOG4105BZU	Histidine kinase
TherJR_1731	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
TherJR_1732	ENOG4105DC7	peptidase M24
TherJR_1733	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
TherJR_1734	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
TherJR_1738	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TherJR_1739	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
TherJR_1740	ENOG4105D49	3-dehydroquinate synthase
TherJR_1741	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
TherJR_1742	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
TherJR_1749	ENOG4105WMT	general secretion pathway protein h
TherJR_1750	ENOG4106A3R	peptidase
TherJR_1751	ENOG4108VAU	general secretion pathway protein G
TherJR_1752	ENOG4105D7Q	type ii secretion system
TherJR_1753	ENOG4105CZX	twitching motility protein
TherJR_1754	ENOG4107QHF	type ii secretion system protein e
TherJR_1756	ENOG4105E2X	shikimate dehydrogenase
TherJR_1758	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
TherJR_1759	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
TherJR_1762	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
TherJR_1765	ENOG4105BZU	Histidine kinase
TherJR_1766	ENOG4105VFE	sira family
TherJR_1767	ENOG4105EM7	Selenocysteine-specific translation elongation factor
TherJR_1768	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
TherJR_1769	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
TherJR_1770	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
TherJR_1771	ENOG4105EV6	Pfam:DUF178
TherJR_1772	ENOG4105DVY	radical SAM domain protein
TherJR_1773	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
TherJR_1774	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TherJR_1778	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
TherJR_1780	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
TherJR_1781	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
TherJR_1782	ENOG4108R6K	riboflavin synthase, subunit alpha
TherJR_1783	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
TherJR_1784	ENOG4105WG9	Conserved Protein
TherJR_1785	ENOG4105DJV	ribulose-phosphate 3-epimerase
TherJR_1786	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
TherJR_1787	ENOG4105D9P	serine threonine protein kinase
TherJR_1788	ENOG4105CJN	penicillin-binding protein
TherJR_1790	ENOG4108ZF3	Phosphatase
TherJR_1793	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
TherJR_1794	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TherJR_1796	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
TherJR_1797	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
TherJR_1798	ENOG4105C25	Primosomal protein n'
TherJR_1799	ENOG4105IH7	synthase
TherJR_1802	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
TherJR_1806	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
TherJR_1807	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
TherJR_1808	ENOG41084KE	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
TherJR_1809	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
TherJR_1810	ENOG4105KC4	UPF0296 protein
TherJR_1811	ENOG4105DSJ	YicC domain protein
TherJR_1812	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
TherJR_1813	ENOG4105CHM	Aminotransferase
TherJR_1814	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
TherJR_1815	ENOG4105F23	Fibronectin-binding protein
TherJR_1816	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
TherJR_1819	ENOG4107WHI	formate dehydrogenase, beta subunit
TherJR_1822	ENOG4105C8Q	Methyl-accepting chemotaxis
TherJR_1823	ENOG4105CI3	gtp-binding protein typa
TherJR_1824	ENOG4105EWC	Purine nucleoside phosphorylase
TherJR_1826	ENOG4107XPQ	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
TherJR_1827	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
TherJR_1828	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
TherJR_1829	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
TherJR_1830	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
TherJR_1831	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
TherJR_1832	ENOG4105CD3	dihydroorotase
TherJR_1833	ENOG4105CXT	aspartate transcarbamylase
TherJR_1834	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
TherJR_1837	ENOG4105C34	Pseudouridine synthase
TherJR_1838	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
TherJR_1840	ENOG4108TVJ	Nitroreductase
TherJR_1847	ENOG4108W6G	cytochrome C
TherJR_1848	ENOG4105WH1	Two component transcriptional regulator luxr family
TherJR_1850	ENOG4105CAG	UPF0210 protein
TherJR_1851	ENOG4105VUC	UPF0237 protein
TherJR_1853	ENOG4108U7W	acetyltransferase
TherJR_1854	ENOG41082AN	stage II sporulation protein
TherJR_1856	ENOG4108ESY	Metal dependent phosphohydrolase
TherJR_1858	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
TherJR_1860	ENOG4105VZ9	UPF0235 protein
TherJR_1862	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
TherJR_1863	ENOG4105BZ4	penicillin-binding protein
TherJR_1865	ENOG4105C98	muts2 protein
TherJR_1866	ENOG4105CFP	Peptidase U32
TherJR_1868	ENOG4105DCG	PHP domain protein
TherJR_1869	ENOG410687F	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
TherJR_1870	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
TherJR_1871	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
TherJR_1872	ENOG4108RWN	rrna methyltransferase
TherJR_1873	ENOG4107ZYR	domain protein
TherJR_1874	ENOG4105CZN	Potassium uptake protein
TherJR_1875	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
TherJR_1876	ENOG4105VJV	50s ribosomal protein L35
TherJR_1877	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
TherJR_1878	ENOG4105C22	threonyL-tRNA synthetase
TherJR_1879	ENOG4108UH6	UPF0754 membrane protein
TherJR_1885	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
TherJR_1889	ENOG4105FB9	CRISPR-associated protein
TherJR_1891	ENOG4107XRG	penicillin-binding protein
TherJR_1894	ENOG4105CFP	Peptidase U32
TherJR_1896	ENOG4105HHA	aminodeoxychorismate lyase
TherJR_1898	ENOG41073R8	VanW family
TherJR_1899	ENOG41085AS	UPF0473 protein
TherJR_1900	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
TherJR_1901	ENOG4107SET	aldo keto reductase
TherJR_1902	ENOG4105VBH	UPF0297 protein
TherJR_1904	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TherJR_1906	ENOG4105C02	permease
TherJR_1908	ENOG41060CR	
TherJR_1911	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
TherJR_1912	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
TherJR_1919	ENOG4105N80	Ferric uptake regulator, Fur family
TherJR_1921	ENOG4105VPX	protein, conserved in bacteria
TherJR_1922	ENOG4105CUZ	uba thif-type nad fad binding protein
TherJR_1923	ENOG4105C9M	aspartyl-trna synthetase
TherJR_1924	ENOG4105CUT	histidyl-tRNA synthetase
TherJR_1926	ENOG4105D4P	Coproporphyrinogen iii oxidase
TherJR_1928	ENOG4105CKP	Polysaccharide Biosynthesis Protein
TherJR_1929	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
TherJR_1930	ENOG4105YAC	
TherJR_1931	ENOG4105EUJ	GTP cyclohydrolase i
TherJR_1934	ENOG4105BZU	Histidine kinase
TherJR_1937	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
TherJR_1938	ENOG4108RC0	Electron transport protein
TherJR_1941	ENOG4107QWP	ABC-2 type transporter
TherJR_1942	ENOG4105CJ1	ABC, transporter
TherJR_1947	ENOG4105BZU	Histidine kinase
TherJR_1949	ENOG4107SHJ	sulfite reductase subunit b
TherJR_1957	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
TherJR_1958	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
TherJR_1959	ENOG4105DVT	helicase
TherJR_1960	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
TherJR_1962	ENOG4105C3M	thioredoxin reductase
TherJR_1964	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
TherJR_1965	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
TherJR_1976	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
TherJR_1977	ENOG4105D9P	serine threonine protein kinase
TherJR_1984	ENOG4105DUM	transcriptional regulator, lysR family
TherJR_1985	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
TherJR_1986	ENOG4105VCQ	rubredoxin
TherJR_1989	ENOG4107RH8	nuclease SbcCD subunit D
TherJR_1990	ENOG4105ED1	spovr family
TherJR_1992	ENOG4105CYN	Serine protein kinase
TherJR_2010	ENOG4105EQI	Metal Dependent Phosphohydrolase
TherJR_2012	ENOG4105RYY	domain protein
TherJR_2014	ENOG41084EC	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
TherJR_2016	ENOG4108QA2	CRISPR-associated protein, Csm6
TherJR_2018	ENOG4105G15	CRISPR-associated RAMP protein, Csm5 family
TherJR_2019	ENOG4108T47	CRISPR-associated RAMP protein, Csm4 family
TherJR_2020	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
TherJR_2022	ENOG410695F	Crispr-associated protein, Csm1 family
TherJR_2024	ENOG4108JUB	Transcriptional regulator
TherJR_2026	ENOG4105C0P	Mg chelatase subunit ChlI
TherJR_2027	ENOG4105VFF	UPF0102 protein
TherJR_2028	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TherJR_2029	ENOG4105C8S	subunit m
TherJR_2030	ENOG4105D65	subunit l
TherJR_2033	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TherJR_2034	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
TherJR_2035	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TherJR_2036	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TherJR_2037	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TherJR_2038	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TherJR_2039	ENOG4105CPI	Metal Dependent Phosphohydrolase
TherJR_2041	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
TherJR_2043	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
TherJR_2045	ENOG4108WTY	tRNA (Guanine-N(1)-)-methyltransferase
TherJR_2046	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
TherJR_2047	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
TherJR_2049	ENOG4105VB6	UPF0109 protein
TherJR_2050	ENOG4105K5M	30s ribosomal protein S16
TherJR_2052	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
TherJR_2054	ENOG4105CJ3	phosphate transporter
TherJR_2056	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
TherJR_2058	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
TherJR_2059	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
TherJR_2060	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
TherJR_2061	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
TherJR_2063	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
TherJR_2064	ENOG4105BZU	Histidine kinase
TherJR_2065	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
TherJR_2068	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TherJR_2070	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
TherJR_2073	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
TherJR_2074	ENOG4105CHR	reductase
TherJR_2075	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
TherJR_2077	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
TherJR_2078	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
TherJR_2079	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
TherJR_2080	ENOG41067VY	50S ribosomal protein L32
TherJR_2081	ENOG4105KNH	Nucleic acid-binding protein
TherJR_2082	ENOG4108IJ2	phosphate acetyltransferase
TherJR_2083	ENOG4105CDE	UPF0348 protein
TherJR_2084	ENOG4105H20	Sporulation integral membrane protein YlbJ
TherJR_2086	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
TherJR_2087	ENOG4106H78	methyltransferase
TherJR_2089	ENOG4107EF8	Glycosyl transferase (Group 1
TherJR_2092	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
TherJR_2093	ENOG4105CEF	Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity)
TherJR_2095	ENOG4107QHI	-hydrogenase
TherJR_2099	ENOG4105CB5	ATP-dependent DNA helicase recG
TherJR_2100	ENOG4105EPR	degv family
TherJR_2101	ENOG4105DP4	dak2 domain fusion protein ylov
TherJR_2102	ENOG4108ZAA	Alkaline-shock protein
TherJR_2104	ENOG4105VB9	50S ribosomal protein l28
TherJR_2105	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
TherJR_2106	ENOG4108RE9	Phosphodiesterase
TherJR_2109	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
TherJR_2111	ENOG4108HU6	Metal dependent phosphohydrolase
TherJR_2112	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TherJR_2113	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
TherJR_2114	ENOG4105D6E	homoserine dehydrogenase
TherJR_2115	ENOG41090I5	UPF0735 ACT domain-containing protein
TherJR_2120	ENOG4105DBK	s4 domain protein
TherJR_2121	ENOG4108VIA	integral membrane protein
TherJR_2123	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
TherJR_2124	ENOG4105DFA	alanine racemase domain protein
TherJR_2126	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
TherJR_2127	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
TherJR_2128	ENOG4105BZU	Histidine kinase
TherJR_2129	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
TherJR_2130	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
TherJR_2131	ENOG4105F0V	Cell wall hydrolase
TherJR_2139	ENOG4105F1A	Pyruvate formate-lyase
TherJR_2141	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
TherJR_2142	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
TherJR_2145	ENOG4105WR5	sporulation protein, YlmC YmxH family
TherJR_2147	ENOG4108ZXQ	stage ii sporulation protein r
TherJR_2148	ENOG4105E65	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TherJR_2149	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TherJR_2150	ENOG4108AWX	Sporulation factor SpoIIGA 
TherJR_2152	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
TherJR_2153	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
TherJR_2154	ENOG4105K67	small basic protein
TherJR_2156	ENOG4108Z36	domain protein, FtsQ-type
TherJR_2157	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
TherJR_2158	ENOG4105D4A	Cell wall formation (By similarity)
TherJR_2159	ENOG4105DFU	Cell wall formation (By similarity)
TherJR_2160	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
TherJR_2161	ENOG4105CNI	cell division protein FtsW
TherJR_2162	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
TherJR_2163	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
TherJR_2164	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
TherJR_2165	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
TherJR_2166	ENOG4105CJN	penicillin-binding protein
TherJR_2168	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
TherJR_2169	ENOG4108V6E	Cell division protein mraZ
TherJR_2172	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
TherJR_2178	ENOG4105CE4	GlcNAc 6-P deacetylase
TherJR_2179	ENOG4105PW4	Sugar fermentation stimulation protein homolog
TherJR_2188	ENOG4108V2W	Carbonate dehydratase
TherJR_2189	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TherJR_2190	ENOG4105C19	ABC transporter
TherJR_2191	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TherJR_2194	ENOG4105D0M	Protease HtpX homolog
TherJR_2197	ENOG4105C8Q	Methyl-accepting chemotaxis
TherJR_2200	ENOG4105DZ1	carboxypeptidase
TherJR_2202	ENOG4105F6S	Spore photoproduct lyase
TherJR_2204	ENOG41080XS	Cobyrinic acid ac-diamide synthase
TherJR_2206	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TherJR_2209	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
TherJR_2210	ENOG4105C8Q	Methyl-accepting chemotaxis
TherJR_2224	ENOG4108K88	Membrane
TherJR_2225	ENOG4108XRC	Protein of unknown function (DUF458) 
TherJR_2227	ENOG4105CVG	Homoserine O-transsuccinylase
TherJR_2229	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
TherJR_2230	ENOG4105CEV	competence damage-inducible protein
TherJR_2231	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
TherJR_2232	ENOG4105E0C	molybdate abc transporter
TherJR_2233	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
TherJR_2235	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
TherJR_2238	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
TherJR_2241	ENOG4105C59	p-type ATPase
TherJR_2242	ENOG4105D06	uba thif-type nad fad binding protein
TherJR_2243	ENOG4105C6T	cysteine synthase
TherJR_2245	ENOG4105KSU	Redox protein
TherJR_2246	ENOG410810Y	Sulfite reductase
TherJR_2247	ENOG4107RIQ	Sulfate adenylate transferase
TherJR_2249	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
TherJR_2250	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
TherJR_2251	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
TherJR_2253	ENOG4107UWC	ABC, transporter
TherJR_2254	ENOG4105D7K	pfkb domain protein
TherJR_2255	ENOG4108UHU	Aldolase
TherJR_2257	ENOG4108IJ9	(ABC) transporter
TherJR_2258	ENOG4105DTQ	mandelate racemase muconate lactonizing
TherJR_2261	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
TherJR_2262	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
TherJR_2263	ENOG4105WEM	extracellular solute-binding protein
TherJR_2264	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
TherJR_2265	ENOG4107258	Transcriptional regulator
TherJR_2267	ENOG4105D01	(LipO)protein
TherJR_2268	ENOG4108UMI	ABC transporter, permease
TherJR_2269	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
TherJR_2272	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
TherJR_2276	ENOG41060IM	Heme exporter protein
TherJR_2278	ENOG4108IUW	ABC transporter
TherJR_2282	ENOG4105DA4	cytochrome c-type biogenesis protein
TherJR_2288	ENOG4108Z1Z	gCN5-related N-acetyltransferase
TherJR_2291	ENOG4105VPX	protein, conserved in bacteria
TherJR_2297	ENOG4105EGD	dinuclear metal center protein, YbgI family
TherJR_2302	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TherJR_2303	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
TherJR_2304	ENOG41082VT	Uncharacterized BCR, YaiI/YqxD family COG1671
TherJR_2305	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
TherJR_2307	ENOG4105M7V	2'-5' rna ligase
TherJR_2308	ENOG4108JJB	ABC transporter
TherJR_2311	ENOG4105E2Z	phosphate ABC transporter (Permease
TherJR_2312	ENOG4105C8U	phosphate abc transporter
TherJR_2313	ENOG4105CVA	phosphate
TherJR_2315	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
TherJR_2316	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TherJR_2321	ENOG4107XGZ	Hydrolase
TherJR_2323	ENOG4105BZU	Histidine kinase
TherJR_2326	ENOG4105CTQ	phosphohexokinase
TherJR_2327	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
TherJR_2328	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
TherJR_2330	ENOG4105WP2	Tryptophan RNA-binding attenuator protein
TherJR_2331	ENOG4105C0B	DNA polymerase III (alpha subunit)
TherJR_2333	ENOG4105D58	Diguanylate phosphodiesterase
TherJR_2337	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
TherJR_2338	ENOG4105G5W	regulator Fur family
TherJR_2339	ENOG4105CPK	Glycosyl transferase (Group 1
TherJR_2340	ENOG4105FJR	Lmbe family
TherJR_2342	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
TherJR_2343	ENOG4105IJJ	transcriptional regulator, crp fnr family
TherJR_2344	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
TherJR_2345	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
TherJR_2347	ENOG4107BJW	polysaccharide deacetylase
TherJR_2348	ENOG4105DXX	methyltransferase
TherJR_2350	ENOG4105W87	Cbs domain
TherJR_2353	ENOG4107XM9	(LipO)protein
TherJR_2355	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TherJR_2357	ENOG41073R8	VanW family
TherJR_2362	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
TherJR_2367	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
TherJR_2372	ENOG410867B	UPF0291 protein
TherJR_2383	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TherJR_2384	ENOG4105BZU	Histidine kinase
TherJR_2386	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
TherJR_2387	ENOG4105CHM	Aminotransferase
TherJR_2388	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
TherJR_2393	ENOG4105WEF	catalase
TherJR_2400	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
TherJR_2401	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
TherJR_2403	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
TherJR_2404	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
TherJR_2406	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
TherJR_2408	ENOG4105DZS	Phenylacetate-CoA ligase
TherJR_2411	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
TherJR_2413	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
TherJR_2415	ENOG4105RD8	TRAP dicarboxylate transporter
TherJR_2416	ENOG4105C5W	Aldolase
TherJR_2417	ENOG4105CJW	magnesium transporter
TherJR_2418	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
TherJR_2419	ENOG4105KG3	cytidine deaminase
TherJR_2420	ENOG4108R5T	secreted protein
TherJR_2421	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
TherJR_2422	ENOG4105CTJ	Metal Dependent Phosphohydrolase
TherJR_2423	ENOG4105C9A	Phoh family
TherJR_2425	ENOG41068P3	sporulation protein YqfC
TherJR_2427	ENOG4105DI5	UPF0365 protein
TherJR_2428	ENOG4105F7J	membrane-bound serine protease
TherJR_2430	ENOG4108V0P	LemA family
TherJR_2431	ENOG4108ZF3	Phosphatase
TherJR_2445	ENOG4107YU2	histidine triad (hIT) protein
TherJR_2446	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TherJR_2447	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
TherJR_2448	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
TherJR_2449	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
TherJR_2450	ENOG4105CFG	Acts as a chaperone (By similarity)
TherJR_2451	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TherJR_2453	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
TherJR_2454	ENOG4105CSA	Coproporphyrinogen iii oxidase
TherJR_2455	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
TherJR_2457	ENOG4105CJR	Integral membrane protein (MviN
TherJR_2461	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
TherJR_2462	ENOG4105TQK	DNA polymerase iii, delta' subunit
TherJR_2463	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
TherJR_2464	ENOG4105KQC	Competence protein
TherJR_2465	ENOG4105C0X	amino acid
TherJR_2467	ENOG4108VZI	ErfK ybiS ycfS ynhG family protein
TherJR_2469	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
TherJR_2482	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
TherJR_2488	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
TherJR_2489	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
TherJR_2498	ENOG4107RRM	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
TherJR_2503	ENOG4107RZH	Nitrite and sulphite reductase 4Fe-4S region
TherJR_2505	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
TherJR_2509	ENOG4105C8T	Leucyl-tRNA synthetase
TherJR_2510	ENOG4105CEY	Amp-dependent synthetase and ligase
TherJR_2511	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TherJR_2513	ENOG4108WF2	Metal Dependent Phosphohydrolase
TherJR_2514	ENOG4105VFU	Rna-binding protein
TherJR_2515	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
TherJR_2517	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
TherJR_2518	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
TherJR_2519	ENOG410812S	Rna-binding protein
TherJR_2521	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TherJR_2525	ENOG4105E1K	spore germination protein
TherJR_2526	ENOG4105E1K	spore germination protein
TherJR_2527	ENOG4108Q8B	Spore germination protein
TherJR_2528	ENOG4108NHD	germination protein
TherJR_2529	ENOG4105K46	50S ribosomal protein l27
TherJR_2531	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
TherJR_2534	ENOG4105C03	ribonuclease
TherJR_2536	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TherJR_2539	ENOG4105CNI	cell division protein FtsW
TherJR_2540	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
TherJR_2541	ENOG4107QMS	site-determining protein
TherJR_2542	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
TherJR_2543	ENOG4105CJN	penicillin-binding protein
TherJR_2546	ENOG4105DFF	Rod shape-determining protein mreb
TherJR_2547	ENOG4105W5Q	DNA repair protein (RadC
TherJR_2548	ENOG4108Z03	MAF-like protein
TherJR_2551	ENOG4107QIZ	NADH dehydrogenase
TherJR_2552	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
TherJR_2553	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
TherJR_2555	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
TherJR_2557	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
TherJR_2559	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
TherJR_2560	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
TherJR_2561	ENOG4108IUQ	atp-dependent protease
TherJR_2562	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
TherJR_2563	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
TherJR_2564	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
TherJR_2566	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
TherJR_2567	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
TherJR_2568	ENOG4108RQ5	Beta-lactamase domain-containing protein
TherJR_2569	ENOG4105CIZ	coA-substrate-specific enzyme activase
TherJR_2572	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
TherJR_2574	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
TherJR_2583	ENOG4108WZW	RNA polymerase sigma
TherJR_2584	ENOG4105WJF	
TherJR_2586	ENOG4105D5T	phosphonate abc transporter
TherJR_2588	ENOG4105EKQ	RNA-directed DNA polymerase
TherJR_2591	ENOG41084CE	UPF0342 protein
TherJR_2593	ENOG4105DB7	PHP domain protein
TherJR_2603	ENOG4105N5T	Radical SAM Protein
TherJR_2604	ENOG4105C0D	helicase
TherJR_2607	ENOG4105C4B	ABC transporter, permease
TherJR_2608	ENOG4108T5I	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
TherJR_2611	ENOG4108R6W	Transcriptional regulator, ARAC family
TherJR_2612	ENOG4105C2C	drug resistance transporter, Bcr CflA
TherJR_2614	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
TherJR_2615	ENOG4105CT4	transporter
TherJR_2616	ENOG4105CT4	transporter
TherJR_2619	ENOG4108Q52	Methyltransferase cognate corrinoid protein
TherJR_2622	ENOG4105FDP	GntR family transcriptional regulator
TherJR_2623	ENOG4108Q52	Methyltransferase cognate corrinoid protein
TherJR_2625	ENOG4105DJB	Major Facilitator Superfamily
TherJR_2628	ENOG4108Q52	Methyltransferase cognate corrinoid protein
TherJR_2630	ENOG4105C8Q	Methyl-accepting chemotaxis
TherJR_2632	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TherJR_2633	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
TherJR_2634	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
TherJR_2636	ENOG4105CJ1	ABC, transporter
TherJR_2638	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
TherJR_2639	ENOG4105BZU	Histidine kinase
TherJR_2640	ENOG4105BZU	Histidine kinase
TherJR_2641	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TherJR_2646	ENOG4105KVH	Transcriptional regulator
TherJR_2648	ENOG4108DBC	nitroreductase
TherJR_2650	ENOG41066VF	YeeE YedE family protein
TherJR_2660	ENOG4105BZU	Histidine kinase
TherJR_2661	ENOG4105SYT	Methylenetetrahydrofolate reductase
TherJR_2665	ENOG4108IV0	ABC, transporter
TherJR_2666	ENOG4105C0Z	ABC transporter
TherJR_2667	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
TherJR_2668	ENOG4105C32	Amino acid ABC transporter (Permease)
TherJR_2669	ENOG4105CP9	extracellular ligand-binding receptor
TherJR_2670	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
TherJR_2671	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
TherJR_2672	ENOG41088YS	Glycosyl transferase (Group 1
TherJR_2677	ENOG4105KNI	merR family transcriptional Regulator
TherJR_2681	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TherJR_2683	ENOG4105GR3	Histidine kinase
TherJR_2684	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TherJR_2686	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TherJR_2687	ENOG4105C7J	ABC transporter, permease
TherJR_2690	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
TherJR_2691	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
TherJR_2693	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
TherJR_2695	ENOG4105CEY	Amp-dependent synthetase and ligase
TherJR_2696	ENOG4105CEY	Amp-dependent synthetase and ligase
TherJR_2697	ENOG4105XZU	Preprotein translocase, subunit SecG
TherJR_2700	ENOG4105DVE	abc transporter atp-binding protein
TherJR_2701	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
TherJR_2703	ENOG4105DVE	abc transporter atp-binding protein
TherJR_2704	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
TherJR_2706	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
TherJR_2707	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
TherJR_2708	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
TherJR_2709	ENOG4105CP7	Triose-phosphate isomerase
TherJR_2710	ENOG4105BZA	Phosphoglycerate kinase
TherJR_2713	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TherJR_2715	ENOG4105CIE	May be required for sporulation (By similarity)
TherJR_2718	ENOG4105CHW	UPF0052 protein
TherJR_2719	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
TherJR_2720	ENOG4105DCG	PHP domain protein
TherJR_2721	ENOG4105DKQ	ROK family
TherJR_2722	ENOG4105DCG	PHP domain protein
TherJR_2723	ENOG41086CI	Bifunctional phosphoglucose phosphomannose isomerase
TherJR_2727	ENOG4108KP7	hydrolase
TherJR_2728	ENOG41082T9	Membrane
TherJR_2731	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
TherJR_2732	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
TherJR_2733	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
TherJR_2735	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
TherJR_2739	ENOG41063SB	peptidase
TherJR_2740	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
TherJR_2741	ENOG4105CAK	Cell division ATP-binding protein ftsE
TherJR_2748	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TherJR_2752	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TherJR_2760	ENOG4108NEV	two component transcriptional regulator, LytTR family
TherJR_2764	ENOG4108IUS	Transketolase
TherJR_2765	ENOG4108HHA	Transketolase
TherJR_2766	ENOG4108JYZ	YitT family
TherJR_2769	ENOG4106VK6	Flagellar motor protein
TherJR_2770	ENOG4105E14	MotA TolQ exbB proton channel
TherJR_2771	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
TherJR_2773	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TherJR_2774	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TherJR_2776	ENOG4105MS2	ribosomal subunit Interface protein
TherJR_2777	ENOG4105VEQ	Cold shock protein
TherJR_2779	ENOG4105MQ3	flagellar protein FliS
TherJR_2780	ENOG4105D2T	synthase
TherJR_2782	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
TherJR_2783	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
TherJR_2784	ENOG4105F0R	Cytidylyltransferase
TherJR_2786	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
TherJR_2791	ENOG4107RT6	flagellar hook-associated
TherJR_2792	ENOG41063QE	flagellar protein FlaG
TherJR_2793	ENOG4105I03	Flagellin
TherJR_2794	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
TherJR_2795	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
TherJR_2797	ENOG4105DTJ	flagellar hook-associated protein
TherJR_2798	ENOG4105E1Q	flagellar hook-associated protein
TherJR_2801	ENOG4105RU3	
TherJR_2802	ENOG4105MJ2	Competence protein
TherJR_2804	ENOG4108K0B	C-di-gmp phosphodiesterase
TherJR_2805	ENOG4105BZU	Histidine kinase
TherJR_2810	ENOG4105WH1	Two component transcriptional regulator luxr family
TherJR_2820	ENOG4105H67	Protein of unknown function (DUF421)
TherJR_2821	ENOG4105ESV	Glycosyl transferase, family 4
TherJR_2822	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
TherJR_2823	ENOG4105CJR	Integral membrane protein (MviN
TherJR_2828	ENOG4108KGH	TRANSCRIPTIONal
TherJR_2833	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
TherJR_2840	ENOG4105D3Q	Sugar transferase
TherJR_2842	ENOG4107STW	synthase
TherJR_2843	ENOG4108TJN	glycosyl transferase group 1
TherJR_2846	ENOG4106WTF	Glycosyl transferase, family 2
TherJR_2847	ENOG4107EF8	Glycosyl transferase (Group 1
TherJR_2848	ENOG4108MIC	Mg-protoporphyrin IX methyl transferase
TherJR_2850	ENOG4105E0M	Sulfatase
TherJR_2854	ENOG4108IUZ	ABC transporter
TherJR_2855	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TherJR_2861	ENOG4105CRE	cytochrome C
TherJR_2863	ENOG4105CYP	glycoside hydrolase, family
TherJR_2869	ENOG4105DIN	metallophosphoesterase
TherJR_2870	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
TherJR_2871	ENOG4105T09	s-layer domain-containing protein
TherJR_2876	ENOG4108KGH	TRANSCRIPTIONal
TherJR_2881	ENOG4105CGA	flagellar basal-body rod protein FlgG
TherJR_2882	ENOG4105CGA	flagellar basal-body rod protein FlgG
TherJR_2884	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
TherJR_2886	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TherJR_2887	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
TherJR_2888	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
TherJR_2889	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
TherJR_2890	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
TherJR_2891	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
TherJR_2892	ENOG41085H9	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
TherJR_2893	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
TherJR_2896	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
TherJR_2897	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
TherJR_2898	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
TherJR_2899	ENOG4108YZG	isomerase
TherJR_2901	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
TherJR_2902	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TherJR_2903	ENOG4107RWR	Sodium hydrogen exchanger
TherJR_2904	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
TherJR_2905	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
TherJR_2906	ENOG4105CBJ	Metal-dependent enzyme
TherJR_2907	ENOG41082DI	50s ribosomal protein l31
TherJR_2909	ENOG4105DR5	peptidase
TherJR_2912	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
TherJR_2914	ENOG4105CBT	Fructose-1,6-bisphosphatase
TherJR_2915	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
TherJR_2919	ENOG410812K	response regulator receiver protein
TherJR_2921	ENOG4105D07	Signal peptide peptidase, SppA
TherJR_2922	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
TherJR_2923	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
TherJR_2924	ENOG4105C75	arginyL-tRNA synthetase
TherJR_2930	ENOG4105CHM	Aminotransferase
TherJR_2931	ENOG4108ZB6	transcriptional regulator AsnC family
TherJR_2935	ENOG4105BZU	Histidine kinase
TherJR_2936	ENOG4105BZ4	penicillin-binding protein
TherJR_2937	ENOG4105MSI	germination protein ypeb
TherJR_2939	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
TherJR_2940	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
TherJR_2944	ENOG4108Q52	Methyltransferase cognate corrinoid protein
TherJR_2945	ENOG4105F5V	trimethylamine methyltransferase
TherJR_2946	ENOG4105C94	Transporter
TherJR_2947	ENOG4108QZ0	Tetrahydromethanopterin S-methyltransferase (EC 2.1.1.86)
TherJR_2948	ENOG4105C94	Transporter
TherJR_2950	ENOG4108Q52	Methyltransferase cognate corrinoid protein
TherJR_2951	ENOG4106HBX	Transcriptional Regulator AraC Family
TherJR_2952	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
TherJR_2957	ENOG4105CQS	hydrogenase expression formation protein HypD
TherJR_2958	ENOG41080XS	Cobyrinic acid ac-diamide synthase
TherJR_2959	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
TherJR_2960	ENOG4108RC0	Electron transport protein
TherJR_2962	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
TherJR_2965	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TherJR_2966	ENOG4107TDF	Formate hydrogenlyase subunit 4
TherJR_2967	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TherJR_2969	ENOG41082R7	4-amino-4-deoxychorismate lyase EC 4.1.3.38
TherJR_2970	ENOG4105CRQ	synthase (Component I)
TherJR_2971	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
TherJR_2972	ENOG4105CDU	Replicative dna helicase
TherJR_2973	ENOG4108IUQ	atp-dependent protease
TherJR_2974	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
TherJR_2977	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
TherJR_2978	ENOG4108UUM	single-stranded DNA-binding protein
TherJR_2979	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
TherJR_2980	ENOG4105C3G	gtp-binding protein
TherJR_2982	ENOG4105D8X	mechanosensitive ion channel
TherJR_2984	ENOG4105DFM	M18 family aminopeptidase
TherJR_2986	ENOG4107RSS	Hydrogenase accessory protein HypB
TherJR_2988	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
TherJR_2989	ENOG4105E3S	small subunit
TherJR_2991	ENOG4105E3S	small subunit
TherJR_2992	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TherJR_2993	ENOG4108ZDA	Sporulation protein YyaC
TherJR_3000	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
TherJR_3003	ENOG4105C9B	Cysteine desulfurase
TherJR_3004	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
TherJR_3005	ENOG4107QW8	radical SAM domain protein
TherJR_3006	ENOG4105D41	biosynthesis protein thiH
TherJR_3008	ENOG4105FA0	parb-like partition protein
TherJR_3009	ENOG4107QJE	Chromosome Partitioning Protein
TherJR_3010	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
TherJR_3011	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
TherJR_3012	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
TherJR_3013	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
TherJR_3014	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
TherJR_3015	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
TherJR_3016	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
TherJR_3017	ENOG41086RW	50S ribosomal protein l34