locus-tag	class	description
FA954_00010	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FA954_00015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FA954_00025	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FA954_00165	COG0726	polysaccharide deacetylase
FA954_00180	COG0489	protein tyrosine kinase activity
FA954_00185	COG0860	N-Acetylmuramoyl-L-alanine amidase
FA954_00205	COG0753	catalase activity
FA954_00220	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FA954_00225	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FA954_00230	COG0101	tRNA pseudouridine synthase activity
FA954_00235	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FA954_00240	COG1122	ATPase activity
FA954_00250	COG0203	ribosomal protein L17
FA954_00255	COG0202	RNA polymerase activity
FA954_00260	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FA954_00265	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FA954_00270	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FA954_00275	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FA954_00285	COG0024	Methionine aminopeptidase
FA954_00290	COG0563	adenylate kinase activity
FA954_00295	COG0201	protein transport
FA954_00305	COG1841	ribosomal large subunit assembly
FA954_00310	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FA954_00315	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FA954_00320	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FA954_00325	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FA954_00335	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FA954_00340	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FA954_00345	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FA954_00350	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FA954_00355	COG0255	Belongs to the universal ribosomal protein uL29 family
FA954_00360	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FA954_00365	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FA954_00370	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FA954_00375	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FA954_00380	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FA954_00385	COG0089	rRNA binding
FA954_00395	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FA954_00400	COG0051	transcription antitermination factor activity, RNA binding
FA954_00405	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FA954_00410	COG0710	3-dehydroquinate dehydratase activity
FA954_00415	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FA954_00420	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FA954_00425	COG0049	tRNA binding
FA954_00430	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FA954_00435	COG1358	cellular component organization or biogenesis
FA954_00440	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FA954_00445	COG0085	RNA polymerase activity
FA954_00450	COG2813	Specifically methylates the guanine in position
FA954_00455	COG0222	ribosome binding
FA954_00460	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FA954_00465	COG0081	regulation of translation
FA954_00470	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FA954_00475	COG0250	Participates in transcription elongation, termination and antitermination
FA954_00485	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FA954_00500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FA954_00505	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FA954_00510	COG0215	cysteine-tRNA ligase activity
FA954_00515	COG1045	serine acetyltransferase
FA954_00520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FA954_00525	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FA954_00530	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FA954_00535	COG4956	integral membrane protein (PIN domain superfamily)
FA954_00540	COG1329	Transcriptional regulator
FA954_00550	COG1183	phosphatidylcholine synthase activity
FA954_00555	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FA954_00560	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FA954_00565	COG0542	response to heat
FA954_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
FA954_00575	COG3880	PFAM UvrB UvrC protein
FA954_00585	COG1285	pathogenesis
FA954_00595	COG4585	Histidine kinase
FA954_00640	COG0443	Heat shock 70 kDa protein
FA954_00655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FA954_00660	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FA954_00665	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FA954_00670	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FA954_00675	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FA954_00685	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FA954_00690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FA954_00705	COG2208	phosphoserine phosphatase activity
FA954_00725	COG3876	Protein conserved in bacteria
FA954_00745	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FA954_00750	COG3956	TIGRFAM MazG family protein
FA954_00755	COG2244	polysaccharide biosynthetic process
FA954_00760	COG2002	toxin-antitoxin pair type II binding
FA954_00765	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FA954_00770	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FA954_00780	COG0193	aminoacyl-tRNA hydrolase activity
FA954_00785	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FA954_00790	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FA954_00795	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FA954_00800	COG2088	sporulation resulting in formation of a cellular spore
FA954_00805	COG0251	oxidation-reduction process
FA954_00810	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FA954_00815	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FA954_00825	COG4466	Protein conserved in bacteria
FA954_00835	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FA954_00845	COG0084	hydrolase, TatD family'
FA954_00855	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FA954_00855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FA954_00870	COG2002	toxin-antitoxin pair type II binding
FA954_00875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FA954_00875	COG1263	PTS System
FA954_00875	COG2190	(PTS) system
FA954_00880	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FA954_00885	COG2827	Endonuclease containing a URI domain
FA954_00890	COG4467	Involved in initiation control of chromosome replication
FA954_00895	COG1774	PSP1 C-terminal conserved region
FA954_00900	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FA954_00905	COG1982	Orn Lys Arg decarboxylase major
FA954_00950	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FA954_00955	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FA954_00960	COG3852	Histidine kinase
FA954_00970	COG2190	(PTS) system
FA954_00970	COG1263	PTS System
FA954_00970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FA954_00975	COG0366	Alpha amylase catalytic
FA954_00980	COG2188	Transcriptional regulator
FA954_00985	COG0095	Lipoate-protein ligase
FA954_00995	COG0655	NAD(P)H dehydrogenase (quinone) activity
FA954_01000	COG2814	Major facilitator Superfamily
FA954_01005	COG1566	PFAM secretion protein HlyD family protein
FA954_01010	COG1566	PFAM secretion protein HlyD family protein
FA954_01015	COG1846	Transcriptional regulator
FA954_01020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FA954_01030	COG0584	glycerophosphoryl diester phosphodiesterase
FA954_01050	COG2211	Major facilitator Superfamily
FA954_01060	COG1070	Carbohydrate kinase
FA954_01085	COG1070	Carbohydrate kinase
FA954_01090	COG2610	gluconate transmembrane transporter activity
FA954_01095	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FA954_01130	COG0590	tRNA wobble adenosine to inosine editing
FA954_01135	COG0735	belongs to the Fur family
FA954_01140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FA954_01145	COG1121	(ABC) transporter
FA954_01155	COG4195	phage-related replication protein
FA954_01160	COG1511	domain protein
FA954_01175	COG0783	Belongs to the Dps family
FA954_01185	COG2814	Major facilitator Superfamily
FA954_01190	COG0531	amino acid
FA954_01195	COG0367	asparagine synthase
FA954_01205	COG1253	flavin adenine dinucleotide binding
FA954_01210	COG0745	RESPONSE REGULATOR receiver
FA954_01215	COG5002	protein histidine kinase activity
FA954_01230	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FA954_01240	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FA954_01245	COG1686	Belongs to the peptidase S11 family
FA954_01250	COG0516	GMP reductase activity
FA954_01250	COG0517	IMP dehydrogenase activity
FA954_01265	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FA954_01270	COG0187	DNA topoisomerase II activity
FA954_01280	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FA954_01290	COG0592	DNA-directed DNA polymerase activity
FA954_01300	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FA954_01320	COG1847	R3H domain protein
FA954_01325	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FA954_01330	COG0445	tRNA wobble uridine modification
FA954_01335	COG0357	Ribosomal RNA small subunit methyltransferase G
FA954_01350	COG1475	DNA binding
FA954_01355	COG1192	Involved in chromosome partitioning
FA954_01360	COG1475	DNA binding
FA954_01365	COG1104	cysteine desulfurase activity
FA954_01375	COG4481	Protein conserved in bacteria
FA954_01380	COG0012	GTP binding
FA954_01385	COG0360	Binds together with S18 to 16S ribosomal RNA
FA954_01390	COG0629	single-stranded DNA binding
FA954_01395	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FA954_01410	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FA954_01415	COG0359	binds to the 23S rRNA
FA954_01420	COG0305	Participates in initiation and elongation during chromosome replication
FA954_01425	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FA954_01435	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FA954_01445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FA954_01460	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FA954_01475	COG5002	protein histidine kinase activity
FA954_01480	COG0745	RESPONSE REGULATOR receiver
FA954_01485	COG0189	ligase activity
FA954_01495	COG3852	Histidine kinase
FA954_01510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FA954_01515	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FA954_01520	COG0010	Belongs to the arginase family
FA954_01530	COG0018	arginyl-trna synthetase
FA954_01535	COG2815	serine threonine protein kinase
FA954_01535	COG0515	serine threonine protein kinase
FA954_01540	COG3829	transcription factor binding
FA954_01545	COG0604	alcohol dehydrogenase
FA954_01550	COG1509	lysine 2,3-aminomutase activity
FA954_01560	COG1193	negative regulation of DNA recombination
FA954_01565	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FA954_01570	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FA954_01590	COG0247	lactate metabolic process
FA954_01590	COG2181	nitrate reductase activity
FA954_01595	COG0745	RESPONSE REGULATOR receiver
FA954_01600	COG5002	protein histidine kinase activity
FA954_01605	COG0183	Belongs to the thiolase family
FA954_01610	COG1250	3-hydroxyacyl-CoA dehydrogenase
FA954_01615	COG1960	acyl-CoA dehydrogenase activity
FA954_01620	COG1960	acyl-CoA dehydrogenase activity
FA954_01630	COG1309	transcriptional regulator
FA954_01635	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FA954_01635	COG1703	isobutyryl-CoA mutase activity
FA954_01635	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FA954_01640	COG3343	RNA polymerase activity
FA954_01645	COG0504	CTP synthase activity
FA954_01650	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FA954_01660	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FA954_01670	COG2204	response regulator
FA954_01675	COG1607	acyl-coa hydrolase
FA954_01680	COG3246	L-lysine catabolic process to acetate
FA954_01685	COG0191	fructose-bisphosphate aldolase activity
FA954_01690	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FA954_01695	COG1494	fructose-1,6-bisphosphatase
FA954_01700	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FA954_01705	COG0739	heme binding
FA954_01710	COG0254	rRNA binding
FA954_01715	COG1435	thymidine kinase activity
FA954_01725	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FA954_01745	COG0009	L-threonylcarbamoyladenylate synthase
FA954_01750	COG1408	metallophosphoesterase
FA954_01755	COG1971	Probably functions as a manganese efflux pump
FA954_01760	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FA954_01765	COG0698	ribose 5-phosphate isomerase
FA954_01770	COG4475	Protein of unknown function (DUF436)
FA954_01775	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FA954_01780	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FA954_01800	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FA954_01810	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FA954_01815	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FA954_01820	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FA954_01825	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FA954_01835	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA954_01840	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA954_01845	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA954_01855	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FA954_01860	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA954_01875	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FA954_01885	COG1007	ATP synthesis coupled electron transport
FA954_01900	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FA954_01905	COG2385	sporulation resulting in formation of a cellular spore
FA954_01915	COG0739	heme binding
FA954_01920	COG1609	Transcriptional regulator
FA954_01930	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FA954_01935	COG0281	malic enzyme
FA954_01940	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FA954_01945	COG0297	glycogen (starch) synthase activity
FA954_01945	COG0438	transferase activity, transferring glycosyl groups
FA954_01985	COG1316	TRANSCRIPTIONal
FA954_01990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FA954_01995	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FA954_02000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FA954_02005	COG2011	ABC-type metal ion transport system permease component
FA954_02010	COG1464	Belongs to the NlpA lipoprotein family
FA954_02015	COG1739	Uncharacterized protein family UPF0029
FA954_02020	COG1316	TRANSCRIPTIONal
FA954_02030	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FA954_02035	COG2197	response regulator
FA954_02045	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FA954_02050	COG1040	competence protein
FA954_02065	COG0765	amino acid transport
FA954_02075	COG1278	Cold shock
FA954_02080	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FA954_02095	COG0653	protein targeting
FA954_02105	COG1024	Enoyl-CoA hydratase
FA954_02120	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FA954_02125	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FA954_02130	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FA954_02140	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FA954_02160	COG0861	Integral membrane protein TerC family
FA954_02180	COG0137	argininosuccinate synthase activity
FA954_02185	COG0165	Argininosuccinate lyase
FA954_02190	COG2884	Cell division ATP-binding protein ftsE
FA954_02195	COG2177	Part of the ABC transporter FtsEX involved in
FA954_02200	COG4942	peptidase
FA954_02205	COG4942	peptidase
FA954_02215	COG3409	Peptidoglycan-binding domain 1 protein
FA954_02215	COG0793	Belongs to the peptidase S41A family
FA954_02220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FA954_02225	COG0556	nucleotide-excision repair
FA954_02230	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FA954_02250	COG1950	PFAM Membrane protein of
FA954_02255	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FA954_02260	COG3764	Sortase (surface protein transpeptidase)
FA954_02265	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FA954_02270	COG2233	PERMEase
FA954_02285	COG0546	phosphoglycolate phosphatase activity
FA954_02290	COG0110	maltose O-acetyltransferase activity
FA954_02295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FA954_02315	COG0167	dihydroorotate dehydrogenase activity
FA954_02325	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FA954_02330	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FA954_02335	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FA954_02340	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FA954_02345	COG0131	Imidazoleglycerol-phosphate dehydratase
FA954_02350	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FA954_02355	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FA954_02360	COG0107	imidazoleglycerol-phosphate synthase activity
FA954_02365	COG0140	phosphoribosyl-ATP diphosphatase activity
FA954_02365	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FA954_02370	COG0457	Tetratricopeptide repeat
FA954_02375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FA954_02380	COG1940	carbohydrate kinase activity
FA954_02390	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FA954_02395	COG1481	regulation of sporulation
FA954_02400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FA954_02415	COG0740	serine-type endopeptidase activity
FA954_02430	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FA954_02440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FA954_02445	COG0126	phosphoglycerate kinase activity
FA954_02450	COG0149	triose-phosphate isomerase activity
FA954_02460	COG0148	phosphopyruvate hydratase activity
FA954_02465	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FA954_02480	COG1647	Serine aminopeptidase, S33
FA954_02485	COG0557	exoribonuclease II activity
FA954_02490	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FA954_02505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FA954_02505	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FA954_02525	COG0163	prenyltransferase activity
FA954_02530	COG1272	protein, Hemolysin III
FA954_02535	COG0318	PFAM AMP-dependent synthetase and ligase
FA954_02545	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FA954_02555	COG0039	L-malate dehydrogenase activity
FA954_02560	COG1620	l-lactate permease
FA954_02565	COG3189	MarR family transcriptional regulator
FA954_02570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FA954_02570	COG3711	transcriptional antiterminator
FA954_02590	COG1674	ftsk spoiiie
FA954_02605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FA954_02630	COG2091	lysine biosynthetic process via aminoadipic acid
FA954_02640	COG0475	glutathione-regulated potassium exporter activity
FA954_02645	COG3162	membrane
FA954_02650	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FA954_02695	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FA954_02700	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FA954_02720	COG1556	Lactate utilization protein
FA954_02730	COG0247	lactate metabolic process
FA954_02735	COG2186	Transcriptional regulator
FA954_02745	COG0667	Aldo Keto reductase
FA954_02760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FA954_02765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FA954_02765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FA954_02765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FA954_02770	COG1105	Belongs to the carbohydrate kinase PfkB family
FA954_02775	COG1349	DNA-binding transcription factor activity
FA954_02785	COG0646	methionine synthase
FA954_02785	COG1410	methionine synthase
FA954_02790	COG0646	methionine synthase
FA954_02790	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FA954_02800	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FA954_02830	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FA954_02840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FA954_02845	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FA954_02850	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FA954_02850	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FA954_02855	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FA954_02860	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FA954_02865	COG4326	sporulation control protein
FA954_02880	COG1024	Enoyl-CoA hydratase
FA954_02880	COG1250	3-hydroxyacyl-CoA dehydrogenase
FA954_02885	COG0183	Belongs to the thiolase family
FA954_02890	COG1960	acyl-CoA dehydrogenase activity
FA954_02910	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FA954_02920	COG1966	Carbon starvation protein
FA954_02925	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FA954_02930	COG0154	amidase activity
FA954_02935	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FA954_02960	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FA954_02965	COG2252	PERMEase
FA954_02970	COG1597	lipid kinase activity
FA954_02975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FA954_02995	COG0477	Major facilitator Superfamily
FA954_03000	COG2267	carboxylic ester hydrolase activity
FA954_03010	COG0450	alkyl hydroperoxide reductase
FA954_03015	COG0789	Transcriptional regulator
FA954_03020	COG2207	Transcriptional regulator
FA954_03020	COG3708	Transcriptional regulator
FA954_03030	COG2226	methyltransferase
FA954_03050	COG5444	nuclease activity
FA954_03055	COG4750	Nucleotidyl transferase
FA954_03060	COG0697	spore germination
FA954_03070	COG3475	LICD family
FA954_03080	COG1785	Belongs to the alkaline phosphatase family
FA954_03085	COG1307	EDD domain protein, DegV family
FA954_03095	COG1120	ATPase activity
FA954_03100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FA954_03105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FA954_03110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FA954_03120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FA954_03125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FA954_03140	COG0778	Nitroreductase
FA954_03145	COG0860	N-Acetylmuramoyl-L-alanine amidase
FA954_03150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FA954_03160	COG1380	Effector of murein hydrolase LrgA
FA954_03165	COG1346	cytolysis
FA954_03170	COG2814	Major facilitator Superfamily
FA954_03175	COG0583	DNA-binding transcription factor activity
FA954_03180	COG1470	cell adhesion involved in biofilm formation
FA954_03185	COG4496	protein, YerC YecD
FA954_03195	COG0210	DNA helicase
FA954_03200	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FA954_03205	COG1305	Transglutaminase-like
FA954_03210	COG1116	anion transmembrane transporter activity
FA954_03215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FA954_03225	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FA954_03230	COG0564	pseudouridine synthase activity
FA954_03240	COG1028	Short-chain dehydrogenase reductase Sdr
FA954_03245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FA954_03245	COG4499	WXG100 protein secretion system (Wss), protein YukC
FA954_03250	COG3949	Membrane
FA954_03255	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FA954_03275	COG1937	Protein conserved in bacteria
FA954_03285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FA954_03290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FA954_03295	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FA954_03300	COG2096	Adenosyltransferase
FA954_03305	COG1393	Belongs to the ArsC family
FA954_03310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FA954_03315	COG0509	glycine decarboxylation via glycine cleavage system
FA954_03325	COG0572	uridine kinase
FA954_03330	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FA954_03340	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FA954_03345	COG1242	4 iron, 4 sulfur cluster binding
FA954_03350	COG0561	phosphatase activity
FA954_03355	COG1253	flavin adenine dinucleotide binding
FA954_03385	COG0824	Thioesterase
FA954_03415	COG1228	amidohydrolase
FA954_03420	COG0010	Belongs to the arginase family
FA954_03425	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FA954_03435	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FA954_03445	COG1185	polyribonucleotide nucleotidyltransferase activity
FA954_03455	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FA954_03460	COG1414	Transcriptional regulator
FA954_03465	COG1349	DNA-binding transcription factor activity
FA954_03470	COG0602	queuosine metabolic process
FA954_03475	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FA954_03485	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FA954_03500	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FA954_03505	COG4605	iron ion homeostasis
FA954_03510	COG4604	ABC transporter, ATP-binding protein
FA954_03515	COG4607	ABC-type enterochelin transport system periplasmic component
FA954_03530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FA954_03545	COG2002	toxin-antitoxin pair type II binding
FA954_03550	COG1024	Enoyl-CoA hydratase
FA954_03575	COG1271	oxidase subunit
FA954_03580	COG1294	oxidase, subunit
FA954_03600	COG1301	dicarboxylic acid transport
FA954_03645	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FA954_03715	COG0482	sulfurtransferase activity
FA954_03720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FA954_03735	COG1392	Phosphate transport regulator
FA954_03740	COG0306	phosphate transporter
FA954_03745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FA954_03755	COG1104	cysteine desulfurase activity
FA954_03760	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FA954_03770	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FA954_03775	COG1376	ErfK ybiS ycfS ynhG family protein
FA954_03780	COG1376	ErfK ybiS ycfS ynhG family protein
FA954_03795	COG3409	Peptidoglycan-binding domain 1 protein
FA954_03795	COG3773	Cell wall hydrolase
FA954_03805	COG0179	Fumarylacetoacetate (FAA) hydrolase
FA954_03810	COG0460	homoserine dehydrogenase
FA954_03815	COG3620	sequence-specific DNA binding
FA954_03820	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FA954_03830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FA954_03835	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FA954_03840	COG0506	proline dehydrogenase activity
FA954_03845	COG1012	belongs to the aldehyde dehydrogenase family
FA954_03855	COG2851	Citrate transporter
FA954_03875	COG1012	belongs to the aldehyde dehydrogenase family
FA954_03890	COG3773	Cell wall hydrolase
FA954_03905	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FA954_03915	COG0175	sulfate reduction
FA954_03920	COG2046	Belongs to the sulfate adenylyltransferase family
FA954_03925	COG0730	response to heat
FA954_03930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FA954_03935	COG1268	BioY protein
FA954_03950	COG0066	3-isopropylmalate dehydratase activity
FA954_03955	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FA954_03965	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FA954_03975	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FA954_03980	COG0406	alpha-ribazole phosphatase activity
FA954_03990	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FA954_03995	COG2112	serine threonine protein kinase
FA954_04000	COG1832	CoA-binding protein
FA954_04040	COG0538	isocitrate dehydrogenase activity
FA954_04045	COG1472	Belongs to the glycosyl hydrolase 3 family
FA954_04065	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FA954_04065	COG1605	Chorismate mutase
FA954_04080	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FA954_04090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FA954_04095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FA954_04100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FA954_04105	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FA954_04115	COG0574	Belongs to the PEP-utilizing enzyme family
FA954_04115	COG3848	Pyruvate phosphate dikinase
FA954_04120	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FA954_04125	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FA954_04140	COG0406	alpha-ribazole phosphatase activity
FA954_04160	COG1028	Short-chain dehydrogenase reductase Sdr
FA954_04180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FA954_04190	COG1126	abc transporter atp-binding protein
FA954_04195	COG1956	GAF domain-containing protein
FA954_04205	COG2190	(PTS) system
FA954_04210	COG1363	Peptidase, m42
FA954_04220	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FA954_04225	COG2066	Belongs to the glutaminase family
FA954_04230	COG4838	Belongs to the UPF0358 family
FA954_04235	COG0387	Pfam Sodium calcium exchanger
FA954_04245	COG1302	Protein conserved in bacteria
FA954_04255	COG1473	amidohydrolase
FA954_04260	COG0517	IMP dehydrogenase activity
FA954_04270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FA954_04295	COG2239	Acts as a magnesium transporter
FA954_04315	COG3679	Belongs to the UPF0342 family
FA954_04320	COG4471	UPF0298 protein
FA954_04335	COG3339	Conserved Protein
FA954_04340	COG2894	cell division
FA954_04365	COG1757	Na H antiporter
FA954_04380	COG2050	protein possibly involved in aromatic compounds catabolism
FA954_04385	COG1024	Enoyl-CoA hydratase
FA954_04395	COG1250	3-hydroxyacyl-CoA dehydrogenase
FA954_04400	COG1250	3-hydroxyacyl-CoA dehydrogenase
FA954_04405	COG0183	Belongs to the thiolase family
FA954_04415	COG3396	Phenylacetate-CoA oxygenase
FA954_04430	COG2151	metal-sulfur cluster biosynthetic enzyme
FA954_04435	COG1012	belongs to the aldehyde dehydrogenase family
FA954_04440	COG2070	2-Nitropropane dioxygenase
FA954_04445	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FA954_04450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FA954_04470	COG3546	catalase activity
FA954_04490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FA954_04510	COG0768	penicillin binding
FA954_04520	COG0688	phosphatidylethanolamine metabolic process
FA954_04525	COG0705	Rhomboid family
FA954_04530	COG0477	Major facilitator Superfamily
FA954_04540	COG1012	belongs to the aldehyde dehydrogenase family
FA954_04545	COG0673	inositol 2-dehydrogenase activity
FA954_04550	COG0154	amidase activity
FA954_04575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FA954_04580	COG1490	D-aminoacyl-tRNA deacylase activity
FA954_04585	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FA954_04590	COG2363	Small membrane protein
FA954_04600	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FA954_04615	COG5577	PFAM Coat F domain
FA954_04635	COG1959	2 iron, 2 sulfur cluster binding
FA954_04640	COG1104	cysteine desulfurase activity
FA954_04650	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FA954_04670	COG0628	permease
FA954_04675	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FA954_04680	COG4472	Bacterial protein of unknown function (DUF965)
FA954_04690	COG3906	Belongs to the UPF0473 family
FA954_04695	COG3906	Belongs to the UPF0473 family
FA954_04700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FA954_04705	COG0768	penicillin binding
FA954_04720	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FA954_04725	COG1914	H( )-stimulated, divalent metal cation uptake system
FA954_04730	COG0788	formyltetrahydrofolate deformylase activity
FA954_04735	COG0569	domain protein
FA954_04735	COG0475	glutathione-regulated potassium exporter activity
FA954_04740	COG3973	AAA domain
FA954_04745	COG1609	Transcriptional regulator
FA954_04750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FA954_04755	COG1869	D-ribose catabolic process
FA954_04760	COG1129	ABC transporter
FA954_04765	COG1172	Belongs to the binding-protein-dependent transport system permease family
FA954_04770	COG1879	ABC-type sugar transport system periplasmic component
FA954_04775	COG0431	NADPH-dependent FMN reductase
FA954_04780	COG0196	riboflavin kinase activity
FA954_04790	COG1960	acyl-CoA dehydrogenase activity
FA954_04800	COG1191	sigma factor activity
FA954_04815	COG0681	Belongs to the peptidase S26 family
FA954_04850	COG2337	Toxic component of a toxin-antitoxin (TA) module
FA954_04860	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FA954_04870	COG1271	oxidase subunit
FA954_04875	COG1294	oxidase, subunit
FA954_04880	COG4988	ABC transporter
FA954_04885	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FA954_04895	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FA954_04905	COG3104	oligopeptide transport
FA954_04920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FA954_04930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FA954_04940	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FA954_04945	COG0656	L-ascorbic acid biosynthetic process
FA954_04950	COG0084	hydrolase, TatD family'
FA954_04955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FA954_04960	COG0436	Aminotransferase
FA954_04970	COG0006	proline dipeptidase activity
FA954_04975	COG1764	response to oxidative stress
FA954_04985	COG2211	Major facilitator Superfamily
FA954_04995	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FA954_05000	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FA954_05005	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FA954_05010	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FA954_05015	COG1713	HD superfamily hydrolase involved in NAD metabolism
FA954_05020	COG0799	negative regulation of ribosome biogenesis
FA954_05025	COG0495	leucyl-tRNA aminoacylation
FA954_05030	COG1596	polysaccharide export
FA954_05030	COG1555	photosystem II stabilization
FA954_05035	COG0626	cystathionine gamma-synthase activity
FA954_05040	COG0626	cystathionine gamma-synthase activity
FA954_05045	COG0717	Belongs to the dCTP deaminase family
FA954_05055	COG2333	competence protein COMEC
FA954_05055	COG0658	competence protein
FA954_05060	COG1595	DNA-templated transcription, initiation
FA954_05070	COG1466	dna polymerase III delta subunit
FA954_05085	COG4846	Membrane protein involved in cytochrome C biogenesis
FA954_05095	COG0268	Binds directly to 16S ribosomal RNA
FA954_05105	COG0860	N-Acetylmuramoyl-L-alanine amidase
FA954_05115	COG0481	GTPase activity
FA954_05120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FA954_05125	COG1420	regulation of RNA biosynthetic process
FA954_05130	COG0459	protein refolding
FA954_05150	COG2264	protein methyltransferase activity
FA954_05155	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FA954_05160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FA954_05170	COG1283	sodium-dependent phosphate transmembrane transporter activity
FA954_05180	COG0537	adenosine 5'-monophosphoramidase activity
FA954_05190	COG1610	YqeY-like protein
FA954_05195	COG1030	water channel activity
FA954_05200	COG4864	UPF0365 protein
FA954_05225	COG1702	phosphate starvation-inducible protein PhoH
FA954_05230	COG1480	7TM receptor with intracellular HD hydrolase
FA954_05240	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FA954_05245	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FA954_05255	COG1381	Involved in DNA repair and RecF pathway recombination
FA954_05260	COG0752	glycyl-tRNA synthetase alpha subunit
FA954_05265	COG0751	glycine-tRNA ligase activity
FA954_05275	COG0517	IMP dehydrogenase activity
FA954_05280	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FA954_05285	COG0574	Belongs to the PEP-utilizing enzyme family
FA954_05285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FA954_05290	COG0358	DNA primase activity
FA954_05295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FA954_05300	COG1960	acyl-CoA dehydrogenase activity
FA954_05305	COG0318	PFAM AMP-dependent synthetase and ligase
FA954_05315	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FA954_05325	COG2384	SAM-dependent methyltransferase
FA954_05330	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FA954_05345	COG1363	Peptidase, m42
FA954_05350	COG0586	Pfam SNARE associated Golgi protein
FA954_05355	COG0456	acetyltransferase
FA954_05360	COG0352	thiamine-phosphate diphosphorylase activity
FA954_05375	COG2022	thiamine diphosphate biosynthetic process
FA954_05380	COG0772	Belongs to the SEDS family
FA954_05385	COG0772	Belongs to the SEDS family
FA954_05395	COG0475	glutathione-regulated potassium exporter activity
FA954_05400	COG2738	Putative neutral zinc metallopeptidase
FA954_05410	COG3599	regulation of cell shape
FA954_05415	COG4166	transmembrane transport
FA954_05420	COG4709	membrane
FA954_05440	COG0288	reversible hydration of carbon dioxide
FA954_05445	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FA954_05455	COG1104	cysteine desulfurase activity
FA954_05460	COG0301	tRNA thio-modification
FA954_05465	COG4187	Peptidase family M20/M25/M40
FA954_05470	COG0861	Integral membrane protein TerC family
FA954_05490	COG4537	Required for transformation and DNA binding
FA954_05520	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FA954_05525	COG2155	Conserved Protein
FA954_05530	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FA954_05540	COG2720	vancomycin resistance protein
FA954_05545	COG3583	domain protein
FA954_05545	COG3584	3D domain protein
FA954_05565	COG0613	PHP domain protein
FA954_05570	COG2153	protein acetylation
FA954_05575	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FA954_05625	COG2390	Transcriptional regulator
FA954_05635	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FA954_05650	COG5505	Protein of unknown function (DUF819)
FA954_05655	COG1322	Protein conserved in bacteria
FA954_05665	COG0671	phosphoesterase, PA-phosphatase related
FA954_05690	COG1982	Orn Lys Arg decarboxylase major
FA954_05695	COG4493	Belongs to the UPF0637 family
FA954_05705	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FA954_05710	COG0584	glycerophosphoryl diester phosphodiesterase
FA954_05715	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FA954_05740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FA954_05745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FA954_05750	COG0785	Cytochrome C biogenesis protein
FA954_05760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FA954_05765	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FA954_05785	COG1024	Enoyl-CoA hydratase
FA954_05795	COG0454	-acetyltransferase
FA954_05800	COG0439	Biotin carboxylase
FA954_05805	COG0511	ligase activity, forming carbon-carbon bonds
FA954_05810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FA954_05815	COG1024	Enoyl-CoA hydratase
FA954_05820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FA954_05825	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FA954_05835	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FA954_05840	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FA954_05845	COG2001	Belongs to the MraZ family
FA954_05850	COG0275	rRNA processing
FA954_05860	COG0768	penicillin binding
FA954_05865	COG0768	penicillin binding
FA954_05870	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FA954_05875	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FA954_05880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FA954_05885	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FA954_05890	COG0772	Belongs to the SEDS family
FA954_05895	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FA954_05900	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FA954_05905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FA954_05915	COG0849	cell division
FA954_05920	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FA954_05930	COG1191	sigma factor activity
FA954_05935	COG1191	sigma factor activity
FA954_05940	COG1873	PFAM PRC-barrel domain
FA954_05950	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FA954_05955	COG1799	cell septum assembly
FA954_05965	COG2302	S4 RNA-binding domain
FA954_05970	COG3599	regulation of cell shape
FA954_05975	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FA954_05980	COG1113	amino acid transport
FA954_05985	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FA954_05990	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FA954_05995	COG0564	pseudouridine synthase activity
FA954_06000	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FA954_06005	COG2233	PERMEase
FA954_06015	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FA954_06030	COG0284	orotidine-5'-phosphate decarboxylase activity
FA954_06035	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FA954_06045	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FA954_06065	COG1363	Peptidase, m42
FA954_06070	COG0531	amino acid
FA954_06075	COG2244	polysaccharide biosynthetic process
FA954_06080	COG1561	YicC-like family, N-terminal region
FA954_06085	COG2052	Domain of unknown function (DUF370)
FA954_06090	COG0194	GDP metabolic process
FA954_06095	COG1758	RNA polymerase activity
FA954_06100	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FA954_06105	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FA954_06110	COG0242	peptide deformylase activity
FA954_06120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FA954_06120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FA954_06125	COG0697	spore germination
FA954_06130	COG0531	amino acid
FA954_06140	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FA954_06145	COG0631	protein serine/threonine phosphatase activity
FA954_06150	COG2815	serine threonine protein kinase
FA954_06150	COG0515	serine threonine protein kinase
FA954_06155	COG1162	GTPase activity
FA954_06160	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FA954_06165	COG3859	Proton-coupled thiamine transporter YuaJ
FA954_06180	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FA954_06185	COG1302	Protein conserved in bacteria
FA954_06190	COG1461	Dihydroxyacetone kinase
FA954_06200	COG1760	l-serine dehydratase
FA954_06205	COG1760	l-serine dehydratase
FA954_06210	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FA954_06225	COG0742	ribosomal rna small subunit methyltransferase
FA954_06235	COG3314	Sporulation integral membrane protein YlbJ
FA954_06240	COG1752	Esterase of the alpha-beta hydrolase superfamily
FA954_06245	COG3480	Lon protease (S16) C-terminal proteolytic domain
FA954_06250	COG1399	metal-binding, possibly nucleic acid-binding protein
FA954_06255	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FA954_06260	COG1349	DNA-binding transcription factor activity
FA954_06265	COG0416	fatty acid biosynthetic process
FA954_06275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FA954_06280	COG1028	Short-chain dehydrogenase reductase Sdr
FA954_06285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FA954_06290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FA954_06315	COG1196	nuclear chromosome segregation
FA954_06320	COG0552	protein localization to endoplasmic reticulum
FA954_06325	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FA954_06330	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FA954_06335	COG0228	four-way junction DNA binding
FA954_06345	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FA954_06350	COG0336	Belongs to the RNA methyltransferase TrmD family
FA954_06355	COG0335	large ribosomal subunit rRNA binding
FA954_06360	COG0681	Belongs to the peptidase S26 family
FA954_06365	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FA954_06370	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FA954_06375	COG0792	nuclease activity
FA954_06380	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FA954_06390	COG0606	chelatase, subunit chli
FA954_06445	COG0606	chelatase, subunit chli
FA954_06470	COG1525	nuclease
FA954_06480	COG0860	N-Acetylmuramoyl-L-alanine amidase
FA954_06485	COG1301	dicarboxylic acid transport
FA954_06490	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FA954_06500	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FA954_06505	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FA954_06510	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FA954_06520	COG1113	amino acid transport
FA954_06530	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FA954_06540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FA954_06580	COG0045	succinate-CoA ligase (ADP-forming) activity
FA954_06585	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FA954_06590	COG0758	DNA mediated transformation
FA954_06595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FA954_06600	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FA954_06605	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FA954_06610	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FA954_06615	COG0052	Belongs to the universal ribosomal protein uS2 family
FA954_06620	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FA954_06625	COG0528	UMP kinase activity
FA954_06630	COG0233	cytoplasmic translational termination
FA954_06640	COG4589	Belongs to the CDS family
FA954_06645	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FA954_06650	COG0750	zinc metalloprotease
FA954_06655	COG0442	prolyl-tRNA aminoacylation
FA954_06700	COG0517	IMP dehydrogenase activity
FA954_06700	COG4175	Glycine betaine
FA954_06710	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FA954_06715	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FA954_06720	COG1447	Phosphotransferase system cellobiose-specific component IIA
FA954_06730	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FA954_06735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FA954_06740	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FA954_06745	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FA954_06755	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FA954_06760	COG1164	Oligoendopeptidase f
FA954_06775	COG0069	glutamate synthase activity
FA954_06780	COG0779	Required for maturation of 30S ribosomal subunits
FA954_06785	COG0195	Participates in both transcription termination and antitermination
FA954_06790	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FA954_06795	COG1358	cellular component organization or biogenesis
FA954_06800	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FA954_06810	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FA954_06815	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FA954_06820	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FA954_06825	COG0196	riboflavin kinase activity
FA954_06830	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FA954_06835	COG1185	polyribonucleotide nucleotidyltransferase activity
FA954_06840	COG0726	polysaccharide deacetylase
FA954_06845	COG0612	Peptidase, M16
FA954_06850	COG0756	dUTP diphosphatase activity
FA954_06865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FA954_06870	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FA954_06875	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FA954_06880	COG0527	aspartate kinase activity
FA954_06885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FA954_06890	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FA954_06900	COG3757	hydrolase, family 25
FA954_06910	COG2076	Multidrug Resistance protein
FA954_06930	COG2376	Dihydroxyacetone kinase
FA954_06935	COG1461	Dihydroxyacetone kinase
FA954_06940	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FA954_06945	COG0740	serine-type endopeptidase activity
FA954_06955	COG1674	ftsk spoiiie
FA954_06960	COG0612	Peptidase, M16
FA954_06965	COG0612	Peptidase, M16
FA954_06970	COG0300	oxidoreductase activity
FA954_06985	COG1426	Protein conserved in bacteria
FA954_06995	COG1426	Protein conserved in bacteria
FA954_07000	COG1426	Protein conserved in bacteria
FA954_07005	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FA954_07010	COG1058	Belongs to the CinA family
FA954_07010	COG1546	Belongs to the CinA family
FA954_07015	COG0513	Belongs to the DEAD box helicase family
FA954_07020	COG2151	metal-sulfur cluster biosynthetic enzyme
FA954_07025	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FA954_07030	COG2137	regulation of response to DNA damage stimulus
FA954_07055	COG1418	mRNA catabolic process
FA954_07060	COG1692	metallophosphoesterase
FA954_07065	COG2359	stage V sporulation protein S
FA954_07075	COG0674	pyruvate-flavodoxin oxidoreductase activity
FA954_07075	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FA954_07080	COG1013	pyruvate-flavodoxin oxidoreductase activity
FA954_07085	COG1234	tRNA 3'-trailer cleavage
FA954_07090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FA954_07095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FA954_07100	COG4550	Control of competence regulator ComK, YlbF/YmcA
FA954_07115	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FA954_07125	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FA954_07130	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FA954_07135	COG2136	Putative SAM-dependent methyltransferase
FA954_07135	COG2521	methyltransferase
FA954_07140	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FA954_07145	COG1923	regulation of RNA biosynthetic process
FA954_07150	COG0464	growth
FA954_07155	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FA954_07160	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FA954_07170	COG0789	Transcriptional regulator
FA954_07175	COG0174	glutamine synthetase
FA954_07185	COG1737	Transcriptional regulator
FA954_07190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FA954_07190	COG1263	PTS System
FA954_07200	COG0561	phosphatase activity
FA954_07210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FA954_07220	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FA954_07225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FA954_07230	COG1845	cytochrome c oxidase, subunit III
FA954_07235	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FA954_07240	COG0109	protoheme IX farnesyltransferase activity
FA954_07250	COG0662	Cupin 2, conserved barrel domain protein
FA954_07255	COG2226	methyltransferase
FA954_07260	COG0535	radical SAM domain protein
FA954_07270	COG2151	metal-sulfur cluster biosynthetic enzyme
FA954_07300	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FA954_07325	COG2318	DinB family
FA954_07335	COG0017	Asparaginyl-tRNA synthetase
FA954_07340	COG3935	DnaD domain protein
FA954_07345	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FA954_07350	COG1737	Transcriptional regulator
FA954_07355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FA954_07355	COG1263	PTS System
FA954_07360	COG2323	membrane
FA954_07365	COG1979	alcohol dehydrogenase
FA954_07370	COG1114	Component of the transport system for branched-chain amino acids
FA954_07375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FA954_07380	COG2814	Major facilitator Superfamily
FA954_07395	COG2608	mercury ion transmembrane transporter activity
FA954_07400	COG2217	Heavy metal translocating P-type atpase
FA954_07405	COG1024	Enoyl-CoA hydratase
FA954_07415	COG0300	oxidoreductase activity
FA954_07435	COG1510	regulation of RNA biosynthetic process
FA954_07445	COG1454	alcohol dehydrogenase
FA954_07455	COG0813	purine-nucleoside phosphorylase activity
FA954_07460	COG0778	Nitroreductase
FA954_07465	COG0456	acetyltransferase
FA954_07490	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FA954_07495	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FA954_07505	COG3336	cytochrome c oxidase
FA954_07540	COG1028	Short-chain dehydrogenase reductase Sdr
FA954_07545	COG2226	methyltransferase
FA954_07600	COG0346	lactoylglutathione lyase activity
FA954_07620	COG2032	superoxide dismutase activity
FA954_07635	COG1741	Belongs to the pirin family
FA954_07640	COG0655	NAD(P)H dehydrogenase (quinone) activity
FA954_07665	COG0456	acetyltransferase
FA954_07680	COG1309	transcriptional regulator
FA954_07695	COG2272	Belongs to the type-B carboxylesterase lipase family
FA954_07710	COG1131	(ABC) transporter
FA954_07715	COG1609	Transcriptional regulator
FA954_07755	COG1280	lysine exporter protein (LysE YggA)
FA954_07795	COG1917	Cupin 2, conserved barrel domain protein
FA954_07795	COG4977	sequence-specific DNA binding
FA954_07800	COG0367	asparagine synthase
FA954_07805	COG0789	Transcriptional regulator
FA954_07845	COG0789	Transcriptional regulator
FA954_07850	COG0019	diaminopimelate decarboxylase activity
FA954_07855	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FA954_07870	COG0697	spore germination
FA954_07880	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FA954_07885	COG1363	Peptidase, m42
FA954_07905	COG1619	proteins homologs of microcin C7 resistance protein MccF
FA954_07910	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FA954_07915	COG0604	alcohol dehydrogenase
FA954_07940	COG0730	response to heat
FA954_07960	COG1028	Short-chain dehydrogenase reductase Sdr
FA954_07970	COG2223	nitrite transmembrane transporter activity
FA954_07980	COG5564	TIM-barrel signal transduction protein
FA954_07990	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FA954_08005	COG1024	Enoyl-CoA hydratase
FA954_08010	COG0183	Belongs to the thiolase family
FA954_08015	COG1028	Short-chain dehydrogenase reductase Sdr
FA954_08020	COG1022	Amp-dependent synthetase and ligase
FA954_08030	COG1960	acyl-CoA dehydrogenase activity
FA954_08045	COG4974	Belongs to the 'phage' integrase family
FA954_08050	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FA954_08060	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FA954_08065	COG1250	3-hydroxyacyl-CoA dehydrogenase
FA954_08070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FA954_08090	COG0402	S-adenosylhomocysteine deaminase activity
FA954_08105	COG1793	dna ligase
FA954_08110	COG0363	glucosamine-6-phosphate deaminase activity
FA954_08115	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FA954_08120	COG2807	transmembrane transport
FA954_08125	COG0531	amino acid
FA954_08135	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FA954_08140	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FA954_08160	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FA954_08165	COG1187	pseudouridine synthase activity
FA954_08170	COG1113	amino acid transport
FA954_08185	COG2391	methyltransferase activity
FA954_08200	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FA954_08215	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FA954_08220	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FA954_08225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FA954_08270	COG0438	transferase activity, transferring glycosyl groups
FA954_08275	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FA954_08280	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FA954_08290	COG1694	Mazg nucleotide pyrophosphohydrolase
FA954_08295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FA954_08305	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FA954_08310	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FA954_08320	COG4347	Protein of unknown function (DUF1405)
FA954_08335	COG0723	plastoquinol--plastocyanin reductase activity
FA954_08345	COG5582	Belongs to the UPF0302 family
FA954_08360	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FA954_08365	COG0287	Prephenate dehydrogenase
FA954_08370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FA954_08375	COG0159	tryptophan synthase activity
FA954_08380	COG0133	tryptophan synthase activity
FA954_08385	COG0135	phosphoribosylanthranilate isomerase activity
FA954_08390	COG0134	indole-3-glycerol-phosphate synthase activity
FA954_08395	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FA954_08405	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FA954_08410	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FA954_08415	COG0105	UTP biosynthetic process
FA954_08435	COG0142	geranyltranstransferase activity
FA954_08455	COG0302	gtp cyclohydrolase
FA954_08460	COG0776	regulation of translation
FA954_08465	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FA954_08485	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FA954_08490	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FA954_08495	COG1160	GTP binding
FA954_08515	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FA954_08520	COG2959	enzyme of heme biosynthesis
FA954_08530	COG0252	asparaginase activity
FA954_08535	COG0492	ferredoxin-NADP+ reductase activity
FA954_08540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FA954_08545	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FA954_08550	COG4862	establishment of competence for transformation
FA954_08575	COG1725	Transcriptional regulator
FA954_08585	COG0210	DNA helicase
FA954_08590	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FA954_08595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FA954_08600	COG4221	oxidoreductase activity
FA954_08605	COG5002	protein histidine kinase activity
FA954_08610	COG0745	RESPONSE REGULATOR receiver
FA954_08615	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FA954_08620	COG1333	cytochrome c biogenesis protein
FA954_08625	COG1187	pseudouridine synthase activity
FA954_08630	COG0700	Nucleoside recognition
FA954_08635	COG2715	membrane protein required for spore maturation
FA954_08640	COG1686	Belongs to the peptidase S11 family
FA954_08645	COG3874	Sporulation protein YtfJ
FA954_08655	COG2213	PTS system mannitol-specific
FA954_08655	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FA954_08660	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FA954_08665	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FA954_08670	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FA954_08675	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FA954_08675	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FA954_08685	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FA954_08685	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FA954_08715	COG2172	sigma factor antagonist activity
FA954_08720	COG1366	Belongs to the anti-sigma-factor antagonist family
FA954_08725	COG1686	Belongs to the peptidase S11 family
FA954_08740	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FA954_08750	COG0686	Belongs to the AlaDH PNT family
FA954_08755	COG0735	belongs to the Fur family
FA954_08760	COG1300	Membrane
FA954_08770	COG1379	DNA repair
FA954_08775	COG0494	nUDIX hydrolase
FA954_08780	COG3546	catalase activity
FA954_08800	COG2217	Heavy metal translocating P-type atpase
FA954_08805	COG2195	Cleaves the N-terminal amino acid of tripeptides
FA954_08810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FA954_08815	COG0346	lactoylglutathione lyase activity
FA954_08820	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FA954_08820	COG1703	isobutyryl-CoA mutase activity
FA954_08820	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FA954_08825	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FA954_08825	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FA954_08830	COG0508	dehydrogenase complex catalyzes the overall conversion of
FA954_08835	COG0022	dehydrogenase e1 component
FA954_08840	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FA954_08845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FA954_08850	COG3426	butyrate kinase activity
FA954_08860	COG0280	phosphate acetyltransferase
FA954_08865	COG3290	protein histidine kinase activity
FA954_08865	COG3829	transcription factor binding
FA954_08885	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FA954_08895	COG0745	RESPONSE REGULATOR receiver
FA954_08925	COG0750	zinc metalloprotease
FA954_08930	COG0497	DNA recombination
FA954_08935	COG1438	arginine binding
FA954_08940	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FA954_08950	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FA954_08955	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FA954_08960	COG0142	geranyltranstransferase activity
FA954_08965	COG1722	exodeoxyribonuclease VII activity
FA954_08970	COG1570	exodeoxyribonuclease VII activity
FA954_08975	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FA954_08985	COG1302	Protein conserved in bacteria
FA954_08990	COG0439	Biotin carboxylase
FA954_08995	COG0511	ligase activity, forming carbon-carbon bonds
FA954_09035	COG3854	ATPases associated with a variety of cellular activities
FA954_09045	COG2814	Major facilitator Superfamily
FA954_09050	COG1809	phosphosulfolactate synthase activity
FA954_09055	COG2707	UPF0756 membrane protein
FA954_09065	COG1413	lyase activity
FA954_09070	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FA954_09075	COG0006	proline dipeptidase activity
FA954_09090	COG3872	metal-dependent enzyme
FA954_09100	COG1752	Esterase of the alpha-beta hydrolase superfamily
FA954_09105	COG1321	iron dependent repressor
FA954_09110	COG0431	NADPH-dependent FMN reductase
FA954_09120	COG2986	histidine ammonia-lyase
FA954_09145	COG0095	Lipoate-protein ligase
FA954_09150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FA954_09155	COG2190	(PTS) system
FA954_09155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FA954_09155	COG1263	PTS System
FA954_09160	COG3711	transcriptional antiterminator
FA954_09170	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FA954_09175	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FA954_09180	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FA954_09185	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FA954_09200	COG1126	abc transporter atp-binding protein
FA954_09205	COG0765	amino acid transport
FA954_09210	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FA954_09215	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FA954_09220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FA954_09240	COG1132	(ABC) transporter
FA954_09245	COG1132	(ABC) transporter
FA954_09255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FA954_09265	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FA954_09270	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FA954_09275	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FA954_09280	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FA954_09280	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FA954_09295	COG2244	polysaccharide biosynthetic process
FA954_09300	COG2323	membrane
FA954_09310	COG1862	Preprotein translocase
FA954_09315	COG0343	queuine tRNA-ribosyltransferase activity
FA954_09320	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FA954_09330	COG2255	four-way junction helicase activity
FA954_09335	COG0632	four-way junction helicase activity
FA954_09340	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FA954_09345	COG0217	transcriptional regulatory protein
FA954_09355	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FA954_09355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FA954_09375	COG1131	(ABC) transporter
FA954_09390	COG0077	Prephenate dehydratase
FA954_09395	COG0083	homoserine kinase activity
FA954_09400	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FA954_09405	COG4492	Belongs to the UPF0735 family
FA954_09410	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FA954_09420	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FA954_09430	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FA954_09435	COG2868	ribosomal protein
FA954_09440	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FA954_09445	COG1994	Peptidase M50
FA954_09455	COG2894	cell division
FA954_09460	COG0850	regulation of cytokinetic process
FA954_09475	COG1077	Cell shape determining protein MreB Mrl
FA954_09480	COG2003	Belongs to the UPF0758 family
FA954_09485	COG0424	maF-like protein
FA954_09495	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FA954_09500	COG2805	Type II/IV secretion system protein
FA954_09505	COG1131	(ABC) transporter
FA954_09520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FA954_09525	COG0285	dihydrofolate synthase activity
FA954_09530	COG0525	valine-tRNA ligase activity
FA954_09540	COG1388	LysM domain
FA954_09545	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FA954_09550	COG0113	porphobilinogen synthase activity
FA954_09560	COG0181	hydroxymethylbilane synthase activity
FA954_09570	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FA954_09575	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FA954_09580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FA954_09585	COG1116	anion transmembrane transporter activity
FA954_09590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FA954_09600	COG0024	Methionine aminopeptidase
FA954_09610	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FA954_09620	COG0470	DNA polymerase III
FA954_09620	COG1067	ATP-dependent peptidase activity
FA954_09630	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FA954_09635	COG0740	serine-type endopeptidase activity
FA954_09640	COG0544	peptidyl-prolyl cis-trans isomerase activity
FA954_09670	COG0183	Belongs to the thiolase family
FA954_09675	COG0318	PFAM AMP-dependent synthetase and ligase
FA954_09680	COG0318	PFAM AMP-dependent synthetase and ligase
FA954_09690	COG1959	2 iron, 2 sulfur cluster binding
FA954_09695	COG5583	Uncharacterized small protein (DUF2292)
FA954_09700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FA954_09710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FA954_09720	COG0534	Mate efflux family protein
FA954_09730	COG5002	protein histidine kinase activity
FA954_09735	COG0745	RESPONSE REGULATOR receiver
FA954_09755	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FA954_09760	COG2226	methyltransferase
FA954_09765	COG2135	peptidase activity
FA954_09850	COG0622	Phosphoesterase
FA954_09855	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FA954_09860	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FA954_09870	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FA954_09875	COG1846	Transcriptional regulator
FA954_09880	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FA954_09890	COG1846	Transcriptional regulator
FA954_09895	COG1304	FMN binding
FA954_09900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FA954_09905	COG1032	radical SAM domain protein
FA954_09915	COG0456	acetyltransferase
FA954_09940	COG2032	superoxide dismutase activity
FA954_09945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FA954_09950	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FA954_09965	COG0010	Belongs to the arginase family
FA954_09970	COG3829	transcription factor binding
FA954_09975	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FA954_09980	COG3829	transcription factor binding
FA954_09980	COG3290	protein histidine kinase activity
FA954_09985	COG1960	acyl-CoA dehydrogenase activity
FA954_09990	COG1960	acyl-CoA dehydrogenase activity
FA954_09995	COG0318	PFAM AMP-dependent synthetase and ligase
FA954_10015	COG2030	dehydratase
FA954_10020	COG1960	acyl-CoA dehydrogenase activity
FA954_10025	COG1028	Short-chain dehydrogenase reductase Sdr
FA954_10060	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FA954_10070	COG2226	methyltransferase
FA954_10080	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FA954_10115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FA954_10120	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FA954_10145	COG3848	Pyruvate phosphate dikinase
FA954_10145	COG0574	Belongs to the PEP-utilizing enzyme family
FA954_10260	COG1492	cobalamin metabolic process
FA954_10275	COG2160	L-arabinose isomerase activity
FA954_10280	COG0235	Class ii aldolase
FA954_10285	COG1609	Transcriptional regulator
FA954_10295	COG1797	cobyrinic acid a,c-diamide synthase activity
FA954_10300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FA954_10305	COG2814	Major facilitator Superfamily
FA954_10345	COG2197	response regulator
FA954_10350	COG0006	proline dipeptidase activity
FA954_10365	COG1733	regulation of RNA biosynthetic process
FA954_10380	COG4086	secreted protein
FA954_10385	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FA954_10390	COG1053	succinate dehydrogenase
FA954_10395	COG2009	succinate dehydrogenase
FA954_10400	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FA954_10405	COG0444	Belongs to the ABC transporter superfamily
FA954_10410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FA954_10415	COG0601	transmembrane transport
FA954_10425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FA954_10430	COG1233	COG1233 Phytoene dehydrogenase and related
FA954_10445	COG0322	excinuclease ABC activity
FA954_10455	COG3118	belongs to the thioredoxin family
FA954_10460	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FA954_10465	COG2086	electron transfer activity
FA954_10470	COG1309	transcriptional regulator
FA954_10475	COG0318	PFAM AMP-dependent synthetase and ligase
FA954_10480	COG0697	spore germination
FA954_10495	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FA954_10495	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FA954_10505	COG4129	membrane
FA954_10520	COG1193	negative regulation of DNA recombination
FA954_10525	COG3773	Cell wall hydrolase
FA954_10525	COG3409	Peptidoglycan-binding domain 1 protein
FA954_10530	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FA954_10530	COG1796	DNA polymerase
FA954_10540	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FA954_10545	COG0072	phenylalanine-tRNA ligase activity
FA954_10545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FA954_10550	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FA954_10555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FA954_10560	COG0569	domain protein
FA954_10575	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FA954_10585	COG0351	phosphomethylpyrimidine kinase
FA954_10590	COG0352	thiamine-phosphate diphosphorylase activity
FA954_10605	COG1649	PFAM Uncharacterised BCR, COG1649
FA954_10610	COG0473	3-isopropylmalate dehydrogenase activity
FA954_10615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FA954_10620	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FA954_10625	COG0440	acetolactate synthase activity
FA954_10630	COG0028	Belongs to the TPP enzyme family
FA954_10645	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FA954_10650	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FA954_10655	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FA954_10660	COG2322	membrane
FA954_10665	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FA954_10680	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FA954_10700	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FA954_10705	COG0386	Belongs to the glutathione peroxidase family
FA954_10710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FA954_10725	COG1971	Probably functions as a manganese efflux pump
FA954_10730	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FA954_10735	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FA954_10735	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FA954_10740	COG1609	Transcriptional regulator
FA954_10785	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FA954_10790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FA954_10795	COG0581	inorganic phosphate transmembrane transporter activity
FA954_10800	COG0573	inorganic phosphate transmembrane transporter activity
FA954_10805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FA954_10810	COG5002	protein histidine kinase activity
FA954_10815	COG0745	RESPONSE REGULATOR receiver
FA954_10830	COG0538	isocitrate dehydrogenase activity
FA954_10835	COG0372	Belongs to the citrate synthase family
FA954_10840	COG0628	permease
FA954_10850	COG0824	Thioesterase
FA954_10860	COG0205	6-phosphofructokinase activity
FA954_10865	COG0825	malonyl-CoA metabolic process
FA954_10870	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FA954_10875	COG2186	Transcriptional regulator
FA954_10880	COG0281	malic enzyme
FA954_10895	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FA954_10920	COG4109	DRTGG domain
FA954_10935	COG0189	ligase activity
FA954_10940	COG0189	ligase activity
FA954_10945	COG0189	ligase activity
FA954_10950	COG0189	ligase activity
FA954_10960	COG0791	NLP P60 protein
FA954_10970	COG2719	SpoVR family
FA954_10975	COG2239	Acts as a magnesium transporter
FA954_10985	COG0697	spore germination
FA954_10990	COG0531	amino acid
FA954_11005	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FA954_11010	COG3844	kynureninase activity
FA954_11030	COG0028	Belongs to the TPP enzyme family
FA954_11035	COG0655	NAD(P)H dehydrogenase (quinone) activity
FA954_11045	COG0318	PFAM AMP-dependent synthetase and ligase
FA954_11050	COG0318	PFAM AMP-dependent synthetase and ligase
FA954_11080	COG0076	glutamate decarboxylase activity
FA954_11095	COG0686	Belongs to the AlaDH PNT family
FA954_11100	COG2508	Transcriptional regulator
FA954_11105	COG0470	DNA polymerase III
FA954_11115	COG1307	EDD domain protein, DegV family
FA954_11120	COG1657	PFAM Prenyltransferase squalene oxidase
FA954_11125	COG1484	DNA-dependent DNA replication
FA954_11155	COG2130	NADP-dependent
FA954_11160	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FA954_11165	COG1131	(ABC) transporter
FA954_11170	COG0460	homoserine dehydrogenase
FA954_11180	COG1253	flavin adenine dinucleotide binding
FA954_11185	COG0501	Belongs to the peptidase M48B family
FA954_11215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FA954_11220	COG1115	amino acid carrier protein
FA954_11225	COG1968	undecaprenyl-diphosphatase activity
FA954_11230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FA954_11250	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FA954_11250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FA954_11260	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FA954_11265	COG0726	polysaccharide deacetylase
FA954_11270	COG1876	peptidase activity
FA954_11280	COG0753	catalase activity
FA954_11285	COG0586	Pfam SNARE associated Golgi protein
FA954_11290	COG4974	Belongs to the 'phage' integrase family
FA954_11295	COG2364	Membrane
FA954_11300	COG3209	COG3209 Rhs family protein
FA954_11305	COG1486	melibiose metabolic process
FA954_11370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FA954_11370	COG0551	DNA topoisomerase type I activity
FA954_11375	COG1231	oxidoreductase activity
FA954_11390	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FA954_11415	COG1279	arginine transmembrane transporter activity
FA954_11425	COG2718	Belongs to the UPF0229 family
FA954_11430	COG2766	serine protein kinase
FA954_11440	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FA954_11455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FA954_11465	COG0328	RNA-DNA hybrid ribonuclease activity
FA954_11475	COG1573	uracil-dna glycosylase
FA954_11480	COG0561	phosphatase activity
FA954_11535	COG1309	transcriptional regulator
FA954_11545	COG0095	Lipoate-protein ligase
FA954_11550	COG0514	ATP-dependent DNA helicase (RecQ)
FA954_11560	COG1234	tRNA 3'-trailer cleavage
FA954_11570	COG0477	Major facilitator Superfamily
FA954_11575	COG0668	transmembrane transport
FA954_11585	COG3591	Belongs to the peptidase S1B family
FA954_11595	COG1331	Highly conserved protein containing a thioredoxin domain
FA954_11605	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FA954_11640	COG3711	transcriptional antiterminator
FA954_11660	COG0398	Pfam SNARE associated Golgi protein
FA954_11670	COG2176	DNA-directed DNA polymerase activity
FA954_11675	COG1012	belongs to the aldehyde dehydrogenase family
FA954_11685	COG2340	Cysteine-rich secretory protein family
FA954_11715	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FA954_11720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FA954_11725	COG1597	lipid kinase activity
FA954_11735	COG1252	NADH dehydrogenase
FA954_11740	COG0492	ferredoxin-NADP+ reductase activity
FA954_11750	COG0316	Belongs to the HesB IscA family
FA954_11760	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FA954_11765	COG4844	belongs to the
FA954_11785	COG2843	Capsule synthesis protein
FA954_11795	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FA954_11800	COG4837	Protein of unknown function (DUF1462)
FA954_11805	COG0626	cystathionine gamma-synthase activity
FA954_11810	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FA954_11815	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FA954_11825	COG1695	Transcriptional regulator
FA954_11855	COG0860	N-Acetylmuramoyl-L-alanine amidase
FA954_11935	COG0740	serine-type endopeptidase activity
FA954_11995	COG1695	Transcriptional regulator
FA954_12015	COG0270	DNA (cytosine-5-)-methyltransferase activity
FA954_12035	COG1396	sequence-specific DNA binding
FA954_12070	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FA954_12080	COG4608	Belongs to the ABC transporter superfamily
FA954_12085	COG0444	Belongs to the ABC transporter superfamily
FA954_12090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FA954_12095	COG0601	transmembrane transport
FA954_12100	COG4166	transmembrane transport
FA954_12105	COG4166	transmembrane transport
FA954_12120	COG1297	OPT oligopeptide transporter protein
FA954_12125	COG0277	FAD linked oxidase domain protein
FA954_12130	COG0247	lactate metabolic process
FA954_12145	COG1028	Short-chain dehydrogenase reductase Sdr
FA954_12150	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FA954_12160	COG0647	UMP catabolic process
FA954_12165	COG2226	methyltransferase
FA954_12175	COG2445	Protein of unknown function DUF86
FA954_12185	COG5577	PFAM Coat F domain
FA954_12205	COG4470	Protein conserved in bacteria
FA954_12215	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FA954_12220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FA954_12225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FA954_12230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FA954_12235	COG0739	heme binding
FA954_12240	COG0531	amino acid
FA954_12245	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FA954_12250	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FA954_12265	COG0747	negative chemotaxis
FA954_12270	COG4608	Belongs to the ABC transporter superfamily
FA954_12275	COG0444	Belongs to the ABC transporter superfamily
FA954_12280	COG0351	phosphomethylpyrimidine kinase
FA954_12300	COG1115	amino acid carrier protein
FA954_12305	COG1755	Isoprenylcysteine carboxyl methyltransferase
FA954_12310	COG3424	synthase
FA954_12325	COG0739	heme binding
FA954_12340	COG0433	COG0433 Predicted ATPase
FA954_12360	COG3764	Sortase (surface protein transpeptidase)
FA954_12385	COG0778	Nitroreductase
FA954_12390	COG0535	radical SAM domain protein
FA954_12400	COG1278	Cold shock
FA954_12405	COG3377	Domain of unknown function (DUF1805)
FA954_12415	COG0737	Belongs to the 5'-nucleotidase family
FA954_12420	COG1801	Protein of unknown function DUF72
FA954_12430	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FA954_12435	COG2224	Isocitrate lyase
FA954_12440	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FA954_12445	COG0628	permease
FA954_12450	COG1295	ribonuclease BN
FA954_12465	COG2171	N-acyltransferase activity
FA954_12470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FA954_12475	COG1473	amidohydrolase
FA954_12505	COG0582	viral genome integration into host DNA
FA954_12515	COG0719	Fe-S assembly protein
FA954_12520	COG0822	iron-sulfur transferase activity
FA954_12525	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FA954_12530	COG0719	Fe-S assembly protein
FA954_12535	COG0396	ATPase activity
FA954_12550	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FA954_12575	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FA954_12580	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FA954_12585	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FA954_12590	COG0235	Class ii aldolase
FA954_12595	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
FA954_12600	COG1850	ribulose-bisphosphate carboxylase activity
FA954_12605	COG0702	epimerase
FA954_12620	COG0477	Major facilitator Superfamily
FA954_12640	COG0735	belongs to the Fur family
FA954_12650	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FA954_12660	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FA954_12680	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FA954_12685	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FA954_12690	COG1263	PTS System
FA954_12690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FA954_12695	COG1486	melibiose metabolic process
FA954_12700	COG1737	Transcriptional regulator
FA954_12705	COG4326	sporulation control protein
FA954_12720	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FA954_12725	COG2346	COG2346, Truncated hemoglobins
FA954_12735	COG0596	Alpha beta hydrolase
FA954_12755	COG1845	cytochrome c oxidase, subunit III
FA954_12780	COG1132	(ABC) transporter
FA954_12785	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FA954_12800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FA954_12815	COG2720	vancomycin resistance protein
FA954_12820	COG1194	a g-specific adenine glycosylase
FA954_12825	COG1988	membrane-bound metal-dependent
FA954_12830	COG0668	transmembrane transport
FA954_12835	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FA954_12840	COG3584	3D domain protein
FA954_12840	COG1388	LysM domain
FA954_12855	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FA954_12870	COG0151	Belongs to the GarS family
FA954_12880	COG0138	bifunctional purine biosynthesis protein purh
FA954_12885	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FA954_12890	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FA954_12895	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FA954_12900	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FA954_12905	COG0047	phosphoribosylformylglycinamidine synthase activity
FA954_12910	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FA954_12915	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FA954_12920	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FA954_12925	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FA954_12930	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FA954_12960	COG2252	PERMEase
FA954_12965	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FA954_12965	COG0519	Catalyzes the synthesis of GMP from XMP
FA954_12970	COG1902	pentaerythritol trinitrate reductase activity
FA954_12990	COG1929	Belongs to the glycerate kinase type-1 family
FA954_12995	COG2610	gluconate transmembrane transporter activity
FA954_13010	COG1028	Short-chain dehydrogenase reductase Sdr
FA954_13100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FA954_13105	COG0028	Belongs to the TPP enzyme family
FA954_13110	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FA954_13120	COG0739	heme binding
FA954_13125	COG0726	polysaccharide deacetylase
FA954_13130	COG1215	transferase activity, transferring glycosyl groups
FA954_13135	COG2814	Major facilitator Superfamily
FA954_13135	COG0477	Major facilitator Superfamily
FA954_13140	COG2115	Belongs to the xylose isomerase family
FA954_13145	COG0459	protein refolding
FA954_13150	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FA954_13160	COG0805	protein transport
FA954_13165	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FA954_13170	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FA954_13175	COG0488	(ABC) transporter
FA954_13180	COG1984	allophanate hydrolase subunit 2
FA954_13185	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FA954_13190	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FA954_13200	COG0456	acetyltransferase
FA954_13205	COG1214	PFAM Peptidase M22, glycoprotease
FA954_13210	COG0802	atpase or kinase
FA954_13215	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FA954_13290	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FA954_13295	COG2084	Dehydrogenase
FA954_13305	COG2183	response to ionizing radiation
FA954_13315	COG3850	Histidine kinase
FA954_13315	COG5002	protein histidine kinase activity
FA954_13325	COG3963	phosphatidate phosphatase activity
FA954_13330	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FA954_13335	COG1191	sigma factor activity
FA954_13340	COG2172	sigma factor antagonist activity
FA954_13350	COG2208	phosphoserine phosphatase activity
FA954_13355	COG2337	Toxic component of a toxin-antitoxin (TA) module
FA954_13360	COG0864	Transcriptional regulator
FA954_13365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FA954_13375	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FA954_13380	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FA954_13380	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FA954_13410	COG0833	amino acid
FA954_13430	COG2205	protein histidine kinase activity
FA954_13435	COG0745	RESPONSE REGULATOR receiver
FA954_13455	COG1396	sequence-specific DNA binding
FA954_13480	COG3173	Aminoglycoside phosphotransferase
FA954_13505	COG1192	Involved in chromosome partitioning
FA954_13545	COG2186	Transcriptional regulator