locus-tag	class	description
AB849_000010	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AB849_000015	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AB849_000020	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AB849_000045	ENOG4105VJY	transcriptional regulator
AB849_000050	ENOG4105CHU	acetyl-coa acetyltransferase
AB849_000055	ENOG4105CEY	Amp-dependent synthetase and ligase
AB849_000070	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
AB849_000080	ENOG4105GVF	(ABC) transporter
AB849_000090	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AB849_000095	ENOG4105E2Y	ABC, transporter
AB849_000100	ENOG4107QJQ	Mate efflux family protein
AB849_000110	ENOG4105BZU	Histidine kinase
AB849_000115	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AB849_000135	ENOG4105NAE	bifunctional deaminase-reductase domain protein
AB849_000140	ENOG4105DVA	methyltransferase
AB849_000145	ENOG4108RAV	Conserved protein
AB849_000215	ENOG4105M59	Phosphodiesterase, mj0936 family
AB849_000220	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AB849_000225	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AB849_000235	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AB849_000240	ENOG41067TZ	transcriptional regulator, MarR family
AB849_000245	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AB849_000255	ENOG41067TZ	transcriptional regulator, MarR family
AB849_000260	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
AB849_000265	ENOG4107AYK	membrAne
AB849_000270	ENOG4107G43	radical SAM domain protein
AB849_000280	ENOG4108YM7	Gcn5-related n-acetyltransferase
AB849_000305	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AB849_000310	ENOG4105DEN	Luciferase family
AB849_000315	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
AB849_000335	ENOG4108JUB	Transcriptional regulator
AB849_000340	ENOG4105C8Y	Acetylornithine aminotransferase
AB849_000345	ENOG4108JUB	Transcriptional regulator
AB849_000350	ENOG4105C1G	acyl-Coa dehydrogenase
AB849_000355	ENOG4105C1G	acyl-Coa dehydrogenase
AB849_000360	ENOG4105CEY	Amp-dependent synthetase and ligase
AB849_000380	ENOG410900P	UPF0336 protein
AB849_000385	ENOG4105C1G	acyl-Coa dehydrogenase
AB849_000390	ENOG4105CHR	reductase
AB849_000435	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
AB849_000445	ENOG4108UV1	cellular component movement
AB849_000455	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AB849_000485	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
AB849_000495	ENOG4107HP6	Transcriptional regulator
AB849_000500	ENOG4105D7K	pfkb domain protein
AB849_000505	ENOG4108RTU	Aldolase
AB849_000510	ENOG4105CXK	mandelate racemase muconate lactonizing
AB849_000515	ENOG4105DJB	Major Facilitator Superfamily
AB849_000520	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AB849_000590	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AB849_000600	ENOG4107QNK	)-transporter
AB849_000605	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
AB849_000610	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
AB849_000615	ENOG4105CMD	Transcriptional regulator, GntR family
AB849_000625	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AB849_000630	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AB849_000645	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
AB849_000650	ENOG4108JUB	Transcriptional regulator
AB849_000665	ENOG4105C26	Dehydrogenase
AB849_000670	ENOG4105PFC	Transcriptional regulator
AB849_000675	ENOG4105DC7	peptidase M24
AB849_000690	ENOG4105KVH	Transcriptional regulator
AB849_000705	ENOG4105PTM	secreted protein
AB849_000710	ENOG4105E33	succinate dehydrogenase
AB849_000720	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
AB849_000725	ENOG4105DWV	Homoserine O-trans-acetylase
AB849_000735	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AB849_000740	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AB849_000750	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AB849_000755	ENOG4105EWK	phytoene
AB849_000770	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AB849_000780	ENOG4105K63	Thioredoxin
AB849_000785	ENOG4105C10	Electron transfer flavoprotein
AB849_000790	ENOG4105BZJ	Electron transfer flavoprotein
AB849_000795	ENOG4107Z3H	Transcriptional regulator, TetR family
AB849_000800	ENOG4105CEY	Amp-dependent synthetase and ligase
AB849_000820	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AB849_000830	ENOG4108QEG	Membrane
AB849_000845	ENOG4105C98	muts2 protein
AB849_000855	ENOG4105DCG	PHP domain protein
AB849_000865	ENOG410687F	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
AB849_000870	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AB849_000875	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AB849_000880	ENOG4108RWN	rrna methyltransferase
AB849_000885	ENOG4107ZYR	domain protein
AB849_000905	ENOG4108R9S	DSBA oxidoreductase
AB849_000910	ENOG4105DWF	phosphomethylpyrimidine kinase
AB849_000915	ENOG4107U6I	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AB849_000930	ENOG4105F32	YngK protein
AB849_000935	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AB849_000940	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AB849_000945	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AB849_000950	ENOG4108ZP8	Acetolactate synthase small subunit
AB849_000955	ENOG4105C7K	acetolactate synthase
AB849_000970	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AB849_000975	ENOG4105VJV	50s ribosomal protein L35
AB849_000980	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AB849_000985	ENOG4108SJC	Membrane
AB849_000990	ENOG4105C22	threonyL-tRNA synthetase
AB849_001005	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
AB849_001025	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AB849_001030	ENOG4108V06	Glutathione peroxidase
AB849_001035	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AB849_001055	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AB849_001060	ENOG4105C2M	dna polymerase I
AB849_001065	ENOG4105ETE	Transcriptional regulator (LacI family
AB849_001070	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
AB849_001080	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
AB849_001085	ENOG4105C26	Dehydrogenase
AB849_001095	ENOG4105DH8	myo-inositol catabolism
AB849_001100	ENOG4105CK5	oxidoreductase
AB849_001105	ENOG4107RUZ	Sss sodium solute transporter superfamily
AB849_001145	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AB849_001150	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AB849_001155	ENOG4105E2Z	phosphate ABC transporter (Permease
AB849_001160	ENOG4105C8U	phosphate abc transporter
AB849_001165	ENOG4105CVA	phosphate
AB849_001170	ENOG4105BZU	Histidine kinase
AB849_001175	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AB849_001190	ENOG4108HMX	isocitrate dehydrogenase (NADP)
AB849_001195	ENOG4105BZN	citrate synthase
AB849_001200	ENOG4108REF	Sporulation integral membrane protein ytvi
AB849_001220	ENOG4105CTQ	phosphohexokinase
AB849_001225	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AB849_001230	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AB849_001235	ENOG41073TP	transcriptional regulator
AB849_001240	ENOG4105C6K	Malic enzyme
AB849_001260	ENOG4105C0B	DNA polymerase III (alpha subunit)
AB849_001265	ENOG4105VV2	
AB849_001290	ENOG4105E8R	UPF0173 metal-dependent hydrolase
AB849_001305	ENOG410839P	
AB849_001310	ENOG410839P	
AB849_001320	ENOG4108QBX	(LipO)protein
AB849_001330	ENOG4105ED1	spovr family
AB849_001335	ENOG4105CJW	magnesium transporter
AB849_001350	ENOG4108Q8B	Spore germination protein
AB849_001365	ENOG4106IPI	cyclase, family
AB849_001370	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
AB849_001395	ENOG4108WS4	fmn reductase
AB849_001405	ENOG4105CEY	Amp-dependent synthetase and ligase
AB849_001440	ENOG4105DY8	decarboxylase
AB849_001455	ENOG4105DCF	alanine dehydrogenase
AB849_001460	ENOG4105G9B	Transcriptional regulator
AB849_001465	ENOG4105FA2	dna polymerase iii
AB849_001475	ENOG4105EPR	degv family
AB849_001480	ENOG4105EWU	Squalene--hopene cyclase
AB849_001515	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
AB849_001520	ENOG4108TU7	Inherit from COG: (ABC) transporter
AB849_001525	ENOG4105CJ1	ABC, transporter
AB849_001530	ENOG4105D6E	homoserine dehydrogenase
AB849_001540	ENOG4105C37	(CBS) domain
AB849_001545	ENOG4105D0M	Protease HtpX homolog
AB849_001570	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AB849_001575	ENOG4105EXW	epimerase dehydratase
AB849_001585	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AB849_001590	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AB849_001600	ENOG4105PGM	cation diffusion facilitator family transporter
AB849_001610	ENOG4108SV8	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity)
AB849_001615	ENOG4108ZJ4	polysaccharide deacetylase
AB849_001620	ENOG4108VXD	carboxy-peptidase
AB849_001635	ENOG4105CH6	catalase
AB849_001640	ENOG4107T5V	SNARE associated Golgi
AB849_001645	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AB849_001660	ENOG4105F8D	glycoside hydrolase family 4
AB849_001745	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AB849_001765	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AB849_001790	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
AB849_001805	ENOG4105CYN	Serine protein kinase
AB849_001815	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AB849_001830	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AB849_001835	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AB849_001840	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AB849_001850	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
AB849_001855	ENOG410667J	hydrolase
AB849_001905	ENOG4108RZE	Tetr family transcriptional regulator
AB849_001915	ENOG4105DF9	Lipoate-protein, ligase
AB849_001920	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AB849_001930	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AB849_001940	ENOG4108ISG	Major Facilitator
AB849_001945	ENOG4105D8X	mechanosensitive ion channel
AB849_001955	ENOG4108CHM	Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases
AB849_001965	ENOG4105C7Z	Conserved Protein
AB849_001975	ENOG4107T8T	UPF0173 metal-dependent hydrolase
AB849_002010	ENOG4105ETD	TRANSCRIPTIONal
AB849_002030	ENOG4108N5C	SNARE associated Golgi protein-related protein
AB849_002040	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AB849_002045	ENOG4105C26	Dehydrogenase
AB849_002055	ENOG4105K4I	Scp-like extracellular
AB849_002090	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
AB849_002095	ENOG4106ZEE	Diacylglycerol kinase
AB849_002105	ENOG4105CEP	NADH dehydrogenase
AB849_002120	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AB849_002130	ENOG4105DVY	radical SAM domain protein
AB849_002135	ENOG4105ZKE	UPF0349 protein
AB849_002155	ENOG4105PNM	synthesis protein
AB849_002165	ENOG4105N98	Capsule biosynthesis protein capB
AB849_002175	ENOG4105C28	cystathionine
AB849_002185	ENOG41083MR	nifu domain-containing protein
AB849_002195	ENOG4108JQ7	(ABC) transporter
AB849_002205	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AB849_002210	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AB849_002235	ENOG4105EPD	Oligopeptide transporter, Opt family
AB849_002240	ENOG4105CQB	FAD linked oxidase domain protein
AB849_002245	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AB849_002265	ENOG4108W5N	phosphatidylglycerophosphatase a
AB849_002275	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
AB849_002280	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AB849_002320	ENOG4105MMD	transcriptional regulator
AB849_002330	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AB849_002335	ENOG4108IHU	transport system permease protein
AB849_002340	ENOG4105DQ5	transport system permease protein
AB849_002345	ENOG4108MES	Periplasmic binding protein
AB849_002350	ENOG4105FAA	peptidase M23
AB849_002355	ENOG4105CUB	amino acid
AB849_002360	ENOG41067VN	Glutaredoxin
AB849_002365	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
AB849_002370	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AB849_002375	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AB849_002380	ENOG4105DEF	Extracellular solute-binding protein, family 5
AB849_002385	ENOG4108JQ7	(ABC) transporter
AB849_002390	ENOG4105C3U	ABC transporter
AB849_002395	ENOG4105DWF	phosphomethylpyrimidine kinase
AB849_002425	ENOG41065KQ	synthase
AB849_002440	ENOG4105DR5	peptidase
AB849_002500	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
AB849_002515	ENOG4105VEQ	Cold shock protein
AB849_002520	ENOG4105KZD	Domain of unknown function (DUF1805)
AB849_002530	ENOG4107R8B	5'-nucleotidase
AB849_002535	ENOG4105I3N	Conserved Protein
AB849_002545	ENOG4105DAP	Nicotinate phosphoribosyltransferase
AB849_002555	ENOG4107QP3	malate synthase g
AB849_002560	ENOG4105C02	permease
AB849_002565	ENOG4107U9T	Pfam:Ribonuclease_BN
AB849_002585	ENOG4105C8Y	Acetylornithine aminotransferase
AB849_002590	ENOG4105CH2	amidohydrolase
AB849_002630	ENOG4105DIW	FeS assembly protein SUFB
AB849_002635	ENOG4108UNV	SUF system FeS assembly protein, NifU family
AB849_002645	ENOG4105JRK	feS assembly protein SufD
AB849_002650	ENOG4105C3K	feS assembly ATPase SufC
AB849_002690	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AB849_002695	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
AB849_002700	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
AB849_002705	ENOG4107V49	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
AB849_002710	ENOG4105JAS	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity)
AB849_002715	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
AB849_002735	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AB849_002740	ENOG4105TUA	UPF0295 protein
AB849_002755	ENOG4105G5W	regulator Fur family
AB849_002765	ENOG4105CSM	endonuclease III
AB849_002775	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AB849_002800	ENOG4105WMR	Protein CrcB homolog
AB849_002805	ENOG4105CI1	PTS System
AB849_002810	ENOG4105F8D	glycoside hydrolase family 4
AB849_002815	ENOG4108Q3X	Transcriptional regulator
AB849_002820	ENOG4108N23	SpoOM-related protein
AB849_002840	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AB849_002845	ENOG4108Z18	K06886 hemoglobin
AB849_002855	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
AB849_002875	ENOG4105CCU	oxidase (Subunit III)
AB849_002885	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
AB849_002890	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AB849_002900	ENOG4105BZ1	(ABC) transporter
AB849_002905	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
AB849_002910	ENOG4105C3F	Signal peptidase i
AB849_002920	ENOG4105II7	pyrroline-5-carboxylate reductase
AB849_002935	ENOG41073R8	VanW family
AB849_002945	ENOG41067AE	Membrane-bound metal-dependent hydrolase
AB849_002950	ENOG4105D8X	mechanosensitive ion channel
AB849_002960	ENOG41069ER	domain protein
AB849_002970	ENOG4105E0A	ABC, transporter
AB849_002990	ENOG4105C12	Phosphoribosylglycinamide synthetase
AB849_003000	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AB849_003005	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AB849_003010	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AB849_003020	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AB849_003025	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
AB849_003030	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
AB849_003035	ENOG4105C8V	SAICAR synthetase
AB849_003040	ENOG4105C83	adenylosuccinate lyase
AB849_003045	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AB849_003050	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AB849_003080	ENOG4105C7N	Xanthine uracil vitamin C permease
AB849_003085	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AB849_003090	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AB849_003110	ENOG4105BZW	Glycerate kinase
AB849_003115	ENOG4107QQ0	gntp family
AB849_003130	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
AB849_003180	ENOG4108IBT	Inherit from COG: transposase
AB849_003210	ENOG4108MA7	Inherit from COG: YD repeat protein
AB849_003215	ENOG4105CZ9	Domain of unknown function (DU1801)
AB849_003220	ENOG4105CK7	Sodium proline symporter
AB849_003245	ENOG4105DR5	peptidase
AB849_003250	ENOG4105CND	Glycosyl transferase, family 2
AB849_003255	ENOG4107QNK	)-transporter
AB849_003260	ENOG4105C93	Xylose Isomerase
AB849_003265	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AB849_003270	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AB849_003280	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AB849_003285	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
AB849_003290	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AB849_003295	ENOG4105C5H	ABC transporter
AB849_003305	ENOG4105E7W	lamb ycsf family protein
AB849_003310	ENOG4105P4J	Allophanate hydrolase, subunit 1
AB849_003315	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AB849_003320	ENOG410801F	ribosomal-protein-alanine acetyltransferase
AB849_003325	ENOG41072GX	Peptidase M22 Glycoprotease
AB849_003330	ENOG4105K8N	protein family UPF0079, ATPase
AB849_003335	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AB849_003400	ENOG4105HFZ	Membrane
AB849_003410	ENOG4105D06	uba thif-type nad fad binding protein
AB849_003415	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AB849_003450	ENOG4105D82	Glutamate dehydrogenase
AB849_003460	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
AB849_003470	ENOG4107SGM	protein serine threonine phosphatase
AB849_003475	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
AB849_003485	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AB849_003495	ENOG4108SGW	outer membrane lipoprotein-sorting protein-like protein
AB849_003500	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AB849_003530	ENOG4108IQI	permease
AB849_003550	ENOG4105BZU	Histidine kinase
AB849_003555	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AB849_003570	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AB849_003575	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AB849_003585	ENOG4105C8B	TIGR00159 family
AB849_003725	ENOG4108NMV	polysaccharide deacetylase
AB849_003740	ENOG4105D1F	ATP-binding protein
AB849_003765	ENOG4105CH6	catalase
AB849_003780	ENOG4108UJD	30S ribosomal protein S9
AB849_003785	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AB849_003790	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AB849_003795	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
AB849_003800	ENOG4108JJB	ABC transporter
AB849_003810	ENOG4108ZT0	50S ribosomal protein l17
AB849_003815	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AB849_003820	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AB849_003825	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AB849_003830	ENOG41067V7	50S ribosomal protein L36
AB849_003835	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AB849_003845	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AB849_003855	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AB849_003865	ENOG4105VPB	50S ribosomal protein L30
AB849_003870	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AB849_003875	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AB849_003880	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AB849_003885	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AB849_003895	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AB849_003900	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AB849_003905	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AB849_003910	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AB849_003915	ENOG41082SA	50s ribosomal protein l29
AB849_003920	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AB849_003925	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AB849_003930	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AB849_003935	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AB849_003940	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AB849_003945	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AB849_003955	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AB849_003960	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AB849_003965	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AB849_003970	ENOG4105FF2	Type I DHQase
AB849_003975	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AB849_003980	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AB849_003985	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AB849_003990	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AB849_003995	ENOG4105XPM	ribosomal protein
AB849_004000	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AB849_004005	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AB849_004010	ENOG4107Y49	methyltransferase
AB849_004015	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AB849_004020	ENOG4108VZM	50s ribosomal protein L10
AB849_004025	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AB849_004030	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AB849_004035	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AB849_004045	ENOG4105WDJ	50S ribosomal protein L33
AB849_004050	ENOG4105QIV	RNA polymerase
AB849_004060	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AB849_004065	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AB849_004070	ENOG4105C8N	cysteinyl-tRNA synthetase
AB849_004075	ENOG4105D7W	serine acetyltransferase
AB849_004080	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AB849_004085	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AB849_004090	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AB849_004095	ENOG4105CTP	PilT protein domain protein
AB849_004100	ENOG4108VJ1	Transcriptional regulator (CarD family
AB849_004110	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AB849_004115	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
AB849_004120	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AB849_004130	ENOG41066A3	ATP guanido phosphotransferase
AB849_004135	ENOG4108Z0C	Uvrb UvrC protein
AB849_004145	ENOG4105KT7	mgtC SapB transporter
AB849_004155	ENOG4105ENE	Histidine kinase
AB849_004200	ENOG4105CFG	Acts as a chaperone (By similarity)
AB849_004215	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AB849_004220	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AB849_004225	ENOG4105KRF	dihydroneopterin aldolase
AB849_004230	ENOG4105EEI	dihydropteroate synthase
AB849_004235	ENOG4105C6T	cysteine synthase
AB849_004245	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
AB849_004250	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AB849_004255	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AB849_004260	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AB849_004285	ENOG4105EHZ	conserved protein UCP016719
AB849_004300	ENOG4105VYY	sporulation protein yabp
AB849_004305	ENOG41082I2	s4 domain protein
AB849_004310	ENOG4108IY2	MazG family
AB849_004320	ENOG4108M14	stage v sporulation protein t
AB849_004330	ENOG4108JA2	transcriptioN-repair coupling factor
AB849_004340	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AB849_004345	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AB849_004350	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AB849_004355	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AB849_004360	ENOG4105K4W	Could be involved in septation (By similarity)
AB849_004365	ENOG4105KME	endoribonuclease L-psp
AB849_004370	ENOG4105DFT	pur operon repressor
AB849_004375	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AB849_004380	ENOG4105XEW	small acid-soluble spore protein
AB849_004385	ENOG4105W42	Veg protein
AB849_004395	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AB849_004400	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
AB849_004405	ENOG4105F8V	Hydrolase, tatD family
AB849_004415	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AB849_004430	ENOG4105KRN	Transcriptional regulator, abrb family
AB849_004435	ENOG4105CI1	PTS System
AB849_004440	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AB849_004445	ENOG41082IR	Excinuclease ABC C subunit domain protein
AB849_004450	ENOG4105QD5	Involved in initiation control of chromosome replication (By similarity)
AB849_004455	ENOG4105MA4	psp1 domain protein
AB849_004460	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AB849_004465	ENOG4105CXN	decarboxylase
AB849_004505	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AB849_004510	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AB849_004515	ENOG4105C6E	dna polymerase iii
AB849_004520	ENOG4105BZU	Histidine kinase
AB849_004530	ENOG4105CI1	PTS System
AB849_004535	ENOG4105CG3	alpha amylase, catalytic region
AB849_004540	ENOG4107414	GntR family transcriptional regulator
AB849_004545	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
AB849_004555	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AB849_004560	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AB849_004565	ENOG4105CW7	secretion protein, HlyD family
AB849_004570	ENOG4105Y49	secretion protein, HlyD family
AB849_004575	ENOG41067TZ	transcriptional regulator, MarR family
AB849_004580	ENOG4108JYZ	YitT family
AB849_004590	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
AB849_004610	ENOG4105CT4	transporter
AB849_004615	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AB849_004620	ENOG4105CMG	Carbohydrate kinase
AB849_004655	ENOG4105CMG	Carbohydrate kinase
AB849_004660	ENOG4105C6Z	Gluconate
AB849_004665	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
AB849_004670	ENOG41065RQ	ADP-ribosylation crystallin J1
AB849_004700	ENOG4108Z6B	deaminase
AB849_004705	ENOG4105N80	Ferric uptake regulator, Fur family
AB849_004715	ENOG4105FDK	ABC transporter
AB849_004725	ENOG4105K7W	phage-related replication protein
AB849_004730	ENOG4105ECB	domain protein
AB849_004735	ENOG41062JF	Transcriptional regulator
AB849_004740	ENOG4105C3M	thioredoxin reductase
AB849_004745	ENOG4108RMU	ferritin dps family protein
AB849_004755	ENOG4105CZM	Major Facilitator
AB849_004760	ENOG4107R7I	amino acid
AB849_004765	ENOG4105CAQ	asparagine synthetase
AB849_004775	ENOG4105C37	(CBS) domain
AB849_004780	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AB849_004785	ENOG4105BZU	Histidine kinase
AB849_004800	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AB849_004810	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
AB849_004820	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AB849_004835	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AB849_004840	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AB849_004860	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AB849_004865	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AB849_004870	ENOG4105VG0	50S ribosomal protein l34
AB849_004885	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AB849_004890	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
AB849_004895	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AB849_004900	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AB849_004905	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AB849_004920	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
AB849_004925	ENOG4107QJE	Chromosome Partitioning Protein
AB849_004930	ENOG4105FA0	parb-like partition protein
AB849_004935	ENOG4105C3J	Cysteine desulfurase
AB849_004940	ENOG4108ZDA	Sporulation protein YyaC
AB849_004945	ENOG4105VDK	protein, conserved in bacteria
AB849_004950	ENOG4105C3G	gtp-binding protein
AB849_004955	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AB849_004960	ENOG4108UUM	single-stranded DNA-binding protein
AB849_004965	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AB849_004980	ENOG4105BZR	domain protein
AB849_004985	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AB849_004990	ENOG4105CDU	Replicative dna helicase
AB849_004995	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AB849_005005	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AB849_005015	ENOG4105C0H	protease
AB849_005030	ENOG4105Q2H	domain protein
AB849_005045	ENOG4105BZU	Histidine kinase
AB849_005050	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AB849_005065	ENOG4105BZU	Histidine kinase
AB849_005070	ENOG4108XFG	YwhD family
AB849_005080	ENOG4105BZ4	penicillin-binding protein
AB849_005085	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AB849_005090	ENOG4105CYW	agmatinase
AB849_005100	ENOG4105C75	arginyL-tRNA synthetase
AB849_005105	ENOG4105D9P	serine threonine protein kinase
AB849_005115	ENOG4105FRY	Dehydrogenase
AB849_005120	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
AB849_005130	ENOG4105C98	muts2 protein
AB849_005135	ENOG4105EQ5	D-Lysine 5,6-aminomutase alpha subunit
AB849_005140	ENOG4107CHF	5,6-aminomutase beta subunit
AB849_005160	ENOG4105DF6	Fe-S oxidoreductase
AB849_005165	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AB849_005170	ENOG4105BZU	Histidine kinase
AB849_005180	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AB849_005185	ENOG4105C1G	acyl-Coa dehydrogenase
AB849_005190	ENOG4105C1G	acyl-Coa dehydrogenase
AB849_005200	ENOG4107Z3H	Transcriptional regulator, TetR family
AB849_005205	ENOG4105D5P	Methylmalonyl-coA mutase
AB849_005210	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
AB849_005215	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AB849_005220	ENOG41064X9	cytochrome C oxidase subunit IV
AB849_005230	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AB849_005240	ENOG410812K	response regulator receiver protein
AB849_005245	ENOG4108UYI	beta-alanyl-CoA ammonia lyase
AB849_005250	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
AB849_005255	ENOG4105D2N	Aldolase
AB849_005260	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AB849_005265	ENOG4105CBT	Fructose-1,6-bisphosphatase
AB849_005270	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AB849_005275	ENOG4105FRN	stage II sporulation protein
AB849_005280	ENOG41082DI	50s ribosomal protein l31
AB849_005285	ENOG4107UGU	thymidine kinase
AB849_005295	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AB849_005300	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AB849_005305	ENOG4108ZXQ	stage ii sporulation protein r
AB849_005315	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AB849_005320	ENOG4107RN3	metallophosphoesterase
AB849_005325	ENOG410815N	Probably functions as a manganese efflux pump (By similarity)
AB849_005330	ENOG4107WAU	Protein tyrosine phosphatase
AB849_005335	ENOG4108YZG	isomerase
AB849_005340	ENOG4108UIC	UPF0340 protein
AB849_005345	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AB849_005350	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AB849_005380	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AB849_005385	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AB849_005390	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AB849_005395	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AB849_005400	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AB849_005405	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AB849_005410	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AB849_005415	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AB849_005420	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AB849_005425	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AB849_005430	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AB849_005445	ENOG4105D65	subunit l
AB849_005450	ENOG4105C8S	subunit m
AB849_005455	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AB849_005470	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AB849_005485	ENOG4105FRN	stage II sporulation protein
AB849_005490	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
AB849_005500	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AB849_005510	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AB849_005515	ENOG4107RA4	Glycosyl transferase (Group 1
AB849_005530	ENOG4107QQG	Dehydrogenase
AB849_005555	ENOG4108KGH	TRANSCRIPTIONal
AB849_005560	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AB849_005570	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AB849_005575	ENOG4108UMI	ABC transporter, permease
AB849_005580	ENOG4105D01	(LipO)protein
AB849_005585	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AB849_005590	ENOG4108KGH	TRANSCRIPTIONal
AB849_005600	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AB849_005605	ENOG4105WH1	Two component transcriptional regulator luxr family
AB849_005620	ENOG41081UC	Inherit from COG: Competence protein
AB849_005630	ENOG4106PMH	Extracellular solute-binding protein family 3
AB849_005635	ENOG4105E5Q	amino acid AbC transporter
AB849_005645	ENOG4105VEQ	Cold shock protein
AB849_005650	ENOG4105MS2	ribosomal subunit Interface protein
AB849_005655	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AB849_005665	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AB849_005675	ENOG4105E39	Enoyl-CoA hydratase
AB849_005690	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AB849_005695	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AB849_005700	ENOG4105CAS	nag kinase
AB849_005710	ENOG4105DBV	ornithine carbamoyltransferase
AB849_005730	ENOG4108ZCF	integral membrane protein
AB849_005750	ENOG4105CDH	Citrulline--aspartate ligase
AB849_005755	ENOG4105CH7	arginosuccinase
AB849_005760	ENOG4105CAK	Cell division ATP-binding protein ftsE
AB849_005765	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AB849_005770	ENOG41063SB	peptidase
AB849_005775	ENOG41063SB	peptidase
AB849_005785	ENOG4105CN1	protease
AB849_005795	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AB849_005800	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AB849_005820	ENOG41086DT	Membrane protein of unknown function
AB849_005835	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
AB849_005855	ENOG4107XGZ	Hydrolase
AB849_005860	ENOG4108S4C	acetyltransferase
AB849_005885	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AB849_005895	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AB849_005900	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
AB849_005905	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AB849_005910	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AB849_005915	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AB849_005920	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AB849_005925	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AB849_005930	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AB849_005935	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AB849_005950	ENOG4105DKQ	ROK family
AB849_005955	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AB849_005960	ENOG4105CHW	UPF0052 protein
AB849_005965	ENOG4105CIE	May be required for sporulation (By similarity)
AB849_005970	ENOG4105KRI	phosphocarrier protein (HPr
AB849_005985	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AB849_006000	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AB849_006015	ENOG4105BZA	Phosphoglycerate kinase
AB849_006020	ENOG4105CP7	Triose-phosphate isomerase
AB849_006030	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AB849_006035	ENOG4105XZU	Preprotein translocase, subunit SecG
AB849_006055	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AB849_006060	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AB849_006095	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
AB849_006100	ENOG4108UT2	hemolysin iii
AB849_006115	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AB849_006125	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AB849_006135	ENOG4105K78	MarR family Transcriptional regulator
AB849_006160	ENOG4105EC2	ftsk spoIIIe
AB849_006175	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AB849_006210	ENOG4107RWR	Sodium hydrogen exchanger
AB849_006265	ENOG4108UIH	futalosine nucleosidase
AB849_006270	ENOG4105E63	Pfam:DUF178
AB849_006280	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
AB849_006290	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AB849_006305	ENOG4105CPC	Aldo Keto reductase
AB849_006310	ENOG4105C28	cystathionine
AB849_006320	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AB849_006325	ENOG4105DM4	PTS System
AB849_006330	ENOG4105DE4	1-phosphofructokinase
AB849_006335	ENOG4105E98	transcriptional regulator DeoR family
AB849_006360	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AB849_006390	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
AB849_006400	ENOG4105KRI	phosphocarrier protein (HPr
AB849_006405	ENOG4105VZJ	PTS System
AB849_006410	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AB849_006415	ENOG4105CTD	carboxy-peptidase
AB849_006420	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AB849_006425	ENOG4108N23	SpoOM-related protein
AB849_006445	ENOG4105CHU	acetyl-coa acetyltransferase
AB849_006450	ENOG4105C1G	acyl-Coa dehydrogenase
AB849_006470	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AB849_006480	ENOG4105D22	carbon starvation protein
AB849_006485	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AB849_006490	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AB849_006495	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AB849_006520	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
AB849_006525	ENOG4105C7N	Xanthine uracil vitamin C permease
AB849_006530	ENOG4105CBD	Diacylglycerol kinase
AB849_006535	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AB849_006555	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AB849_006560	ENOG4107S9D	Alpha beta hydrolase
AB849_006570	ENOG4105D3R	alkyl hydroperoxide reductase
AB849_006575	ENOG4107TXC	Transcriptional regulator
AB849_006585	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AB849_006625	ENOG4105DZR	Type I site-specific deoxyribonuclease
AB849_006670	ENOG4106MCE	EamA-like transporter family
AB849_006675	ENOG4108KN0	Choline kinase
AB849_006680	ENOG4105KPE	licD family
AB849_006690	ENOG4105G6Z	alkaline phosphatase
AB849_006695	ENOG4105EPR	degv family
AB849_006705	ENOG4105E0A	ABC, transporter
AB849_006715	ENOG4105DQ5	transport system permease protein
AB849_006720	ENOG4105EHG	Permease protein
AB849_006735	ENOG4107VFR	oxidoreductase
AB849_006760	ENOG4107ZE5	PPIases accelerate the folding of proteins
AB849_006775	ENOG41067MG	lrgb family
AB849_006780	ENOG4105D94	Major Facilitator Superfamily
AB849_006785	ENOG4107RSM	transcriptional regulator
AB849_006790	ENOG4108R5T	secreted protein
AB849_006795	ENOG4105KGF	protein, YerC YecD
AB849_006805	ENOG4105C4R	Atp-dependent dna helicase
AB849_006810	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AB849_006825	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AB849_006840	ENOG4105EMS	pseudouridine synthase
AB849_006855	ENOG4105BZ4	penicillin-binding protein
AB849_006860	ENOG4108K88	Membrane
AB849_006885	ENOG4105VPX	protein, conserved in bacteria
AB849_006895	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
AB849_006900	ENOG4105EHG	Permease protein
AB849_006905	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
AB849_006910	ENOG4108WBT	adenosyltransferase
AB849_006915	ENOG41080E8	Transcriptional regulator, Spx MgsR family
AB849_006920	ENOG4107R19	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AB849_006925	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AB849_006935	ENOG4105DBI	uridine monophosphokinase
AB849_006940	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
AB849_006945	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AB849_006955	ENOG4105N5T	Radical SAM Protein
AB849_006960	ENOG4105J7I	hydrolase
AB849_006965	ENOG4105C37	(CBS) domain
AB849_006995	ENOG4108TGP	Thioesterase superfamily protein
AB849_007025	ENOG4105CI2	imidazolone-5-propionate hydrolase
AB849_007030	ENOG4108903	Formimidoylglutamase
AB849_007035	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
AB849_007045	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AB849_007050	ENOG4108JJB	ABC transporter
AB849_007055	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AB849_007065	ENOG4108I0Z	Aconitate hydratase
AB849_007070	ENOG4107258	Transcriptional regulator
AB849_007075	ENOG4105E98	transcriptional regulator DeoR family
AB849_007080	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AB849_007085	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AB849_007095	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AB849_007100	ENOG4108Y6J	UPF0403 protein
AB849_007115	ENOG4105DWD	nucleoside recognition domain protein
AB849_007120	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AB849_007125	ENOG4108WZW	RNA polymerase sigma
AB849_007135	ENOG4105KRN	Transcriptional regulator, abrb family
AB849_007140	ENOG4105E39	Enoyl-CoA hydratase
AB849_007190	ENOG4105CK2	sodium dicarboxylate symporter
AB849_007235	ENOG4105DG4	malate L-lactate dehydrogenase
AB849_007305	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AB849_007310	ENOG4105CZN	Potassium uptake protein
AB849_007325	ENOG4107GRR	phosphate transport regulator
AB849_007330	ENOG4105CJ3	phosphate transporter
AB849_007335	ENOG4107QSE	Dipeptidase
AB849_007345	ENOG4107QI6	Cysteine desulfurase
AB849_007350	ENOG4108IYU	L-aspartate oxidase
AB849_007355	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AB849_007360	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AB849_007365	ENOG4108QQZ	ErfK YbiS YcfS YnhG family protein
AB849_007370	ENOG4108VZI	ErfK ybiS ycfS ynhG family protein
AB849_007375	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AB849_007385	ENOG4105F0V	Cell wall hydrolase
AB849_007395	ENOG4105ERH	Fumarylacetoacetate hydrolase
AB849_007400	ENOG4105D6E	homoserine dehydrogenase
AB849_007405	ENOG41067QW	Transcriptional regulator
AB849_007410	ENOG4105HKU	nucleoside recognition domain-containing protein
AB849_007420	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AB849_007425	ENOG4105EFZ	amidohydrolase
AB849_007435	ENOG4105C26	Dehydrogenase
AB849_007445	ENOG4105D4T	Citrate transporter
AB849_007455	ENOG4105D7K	pfkb domain protein
AB849_007475	ENOG4108VA3	3-hexulose-6-phosphate synthase
AB849_007480	ENOG41080HJ	6-phospho 3-hexuloisomerase
AB849_007485	ENOG4105C26	Dehydrogenase
AB849_007500	ENOG4108VKI	Cell wall hydrolase
AB849_007510	ENOG4108V0E	nucleoside 2-deoxyribosyltransferase YtoQ
AB849_007515	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AB849_007525	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AB849_007530	ENOG4107RIQ	Sulfate adenylate transferase
AB849_007535	ENOG410635A	Membrane
AB849_007540	ENOG4105C0H	protease
AB849_007545	ENOG4107ZYJ	bioY protein
AB849_007560	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AB849_007565	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AB849_007570	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
AB849_007575	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AB849_007585	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
AB849_007590	ENOG4105CVJ	phosphoglycerate mutase
AB849_007600	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AB849_007610	ENOG4105K4P	CoA-binding domain protein
AB849_007635	ENOG4108VCI	transcription factor, rsfa family
AB849_007655	ENOG4105D17	glycoside hydrolase, family 3 domain protein
AB849_007675	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AB849_007685	ENOG4105ETE	Transcriptional regulator (LacI family
AB849_007690	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AB849_007705	ENOG4105BZ4	penicillin-binding protein
AB849_007710	ENOG4105BZ4	penicillin-binding protein
AB849_007715	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AB849_007725	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AB849_007730	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AB849_007735	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AB849_007750	ENOG4107TB6	phosphoglycerate mutase
AB849_007760	ENOG4108JUA	Transcriptional regulator
AB849_007770	ENOG4105DTD	Dehydrogenase
AB849_007790	ENOG4106PMH	Extracellular solute-binding protein family 3
AB849_007795	ENOG4105E5Q	amino acid AbC transporter
AB849_007800	ENOG4105CDA	abc transporter atp-binding protein
AB849_007810	ENOG4105C88	aminopeptidase
AB849_007815	ENOG4105C5Y	PTS System
AB849_007820	ENOG4105DER	m42 family
AB849_007835	ENOG4105CSV	Glutaminase
AB849_007840	ENOG4105ZPI	UPF0358 protein
AB849_007845	ENOG4105UPD	Calcium Proton
AB849_007855	ENOG4105VBF	alkaline shock protein
AB849_007870	ENOG41080XP	Cbs domain
AB849_007875	ENOG41090VF	Stage v sporulation protein ac
AB849_007880	ENOG4105CZ3	stage V sporulation protein ad
AB849_007900	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AB849_007905	ENOG4105CJW	magnesium transporter
AB849_007930	ENOG4105WUC	UPF0298 protein
AB849_007950	ENOG4107QMS	site-determining protein
AB849_007975	ENOG4105DFD	Na H antiporter
AB849_007990	ENOG4108VUY	thioesterase Superfamily protein
AB849_007995	ENOG4105E39	Enoyl-CoA hydratase
AB849_008005	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AB849_008010	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AB849_008015	ENOG4105CHU	acetyl-coa acetyltransferase
AB849_008025	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
AB849_008040	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
AB849_008045	ENOG4105C26	Dehydrogenase
AB849_008050	ENOG4105EA8	2-Nitropropane dioxygenase
AB849_008055	ENOG4105JQZ	Methyltransferase
AB849_008060	ENOG41068WN	
AB849_008080	ENOG4105WEF	catalase
AB849_008100	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AB849_008120	ENOG4105CJN	penicillin-binding protein
AB849_008130	ENOG4105DJ4	phosphatidylserine decarboxylase
AB849_008150	ENOG4105C26	Dehydrogenase
AB849_008155	ENOG4105D9R	oxidoreductase
AB849_008160	ENOG4105EUF	amidase EC 3.5.1.4
AB849_008170	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AB849_008185	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AB849_008190	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AB849_008195	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AB849_008200	ENOG4105M08	Membrane
AB849_008205	ENOG4105CUT	histidyl-tRNA synthetase
AB849_008210	ENOG4105C9M	aspartyl-trna synthetase
AB849_008220	ENOG4108UX3	'-nucleotidase
AB849_008250	ENOG4105C3J	Cysteine desulfurase
AB849_008260	ENOG4105C7H	Helicase, RecD TraA family
AB849_008270	ENOG41060CR	
AB849_008280	ENOG4105C02	permease
AB849_008285	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AB849_008290	ENOG4105VBH	UPF0297 protein
AB849_008305	ENOG41085AS	UPF0473 protein
AB849_008315	ENOG4107XRG	penicillin-binding protein
AB849_008330	ENOG4105C94	Transporter
AB849_008335	ENOG4105C5A	transporter
AB849_008340	ENOG4105CIY	formyltetrahydrofolate deformylase
AB849_008350	ENOG4105EEM	helicase
AB849_008355	ENOG4105ETE	Transcriptional regulator (LacI family
AB849_008360	ENOG4108RVA	ribokinase
AB849_008365	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
AB849_008370	ENOG4105C2J	ABC transporter
AB849_008375	ENOG4105CNN	ABC, transporter
AB849_008380	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
AB849_008385	ENOG4108UZX	fmn reductase
AB849_008395	ENOG4105FBW	Monooxygenase
AB849_008410	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AB849_008425	ENOG4105C3F	Signal peptidase i
AB849_008460	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
AB849_008470	ENOG4105GFG	DUF218 domain
AB849_008480	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AB849_008485	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AB849_008490	ENOG4108JJ9	ABC, transporter
AB849_008495	ENOG4108JJ8	(ABC) transporter
AB849_008505	ENOG4108UMN	azlc family
AB849_008515	ENOG4105DUX	Transporter
AB849_008530	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AB849_008535	ENOG4105E2S	oxidase) subunit II
AB849_008540	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AB849_008550	ENOG41060D1	Quinol oxidase
AB849_008560	ENOG4108RE7	deoxyribonuclease
AB849_008565	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
AB849_008580	ENOG4105DC7	peptidase M24
AB849_008585	ENOG4108X3M	OsmC Ohr family protein
AB849_008605	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
AB849_008610	ENOG4105CQW	ribosome biogenesis GTPase YqeH
AB849_008615	ENOG4105E2X	shikimate dehydrogenase
AB849_008620	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AB849_008625	ENOG4108WF2	Metal Dependent Phosphohydrolase
AB849_008635	ENOG4105C8T	Leucyl-tRNA synthetase
AB849_008640	ENOG4105KQC	Competence protein
AB849_008645	ENOG4105C28	cystathionine
AB849_008650	ENOG4105C28	cystathionine
AB849_008655	ENOG4105DHP	deoxycytidine triphosphate deaminase
AB849_008665	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
AB849_008670	ENOG4105EMN	RNA polymerase sigma factor
AB849_008680	ENOG4105TQK	DNA polymerase iii, delta' subunit
AB849_008705	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AB849_008710	ENOG4105CEF	Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity)
AB849_008715	ENOG4108ZRV	stage ii sporulation protein p
AB849_008725	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AB849_008730	ENOG4105CSA	Coproporphyrinogen iii oxidase
AB849_008735	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AB849_008740	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AB849_008760	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AB849_008765	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AB849_008770	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AB849_008775	ENOG41062IR	nudix hydrolase
AB849_008790	ENOG4107YU2	histidine triad (hIT) protein
AB849_008795	ENOG4105VCC	30S ribosomal protein S21
AB849_008800	ENOG4105KTH	gatB Yqey
AB849_008805	ENOG4105F7J	membrane-bound serine protease
AB849_008810	ENOG4105DI5	UPF0365 protein
AB849_008835	ENOG4105C9A	Phoh family
AB849_008840	ENOG4105CTJ	Metal Dependent Phosphohydrolase
AB849_008845	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AB849_008850	ENOG4107YR5	Diacylglycerol kinase
AB849_008855	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AB849_008865	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
AB849_008870	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
AB849_008875	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AB849_008890	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AB849_008895	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AB849_008900	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AB849_008905	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AB849_008910	ENOG4105C1G	acyl-Coa dehydrogenase
AB849_008915	ENOG4105CEY	Amp-dependent synthetase and ligase
AB849_008925	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
AB849_008940	ENOG4105EGD	dinuclear metal center protein, YbgI family
AB849_008955	ENOG4105CN9	Peptidase m42 family protein
AB849_008960	ENOG4107ZTW	SNARE associated Golgi
AB849_008965	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
AB849_008970	ENOG4108VEU	Thiamine monophosphate synthase
AB849_008985	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AB849_008990	ENOG4105CNI	cell division protein FtsW
AB849_008995	ENOG4105CNI	cell division protein FtsW
AB849_009005	ENOG4107RWR	Sodium hydrogen exchanger
AB849_009020	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
AB849_009030	ENOG41063Y9	
AB849_009050	ENOG4108V2W	Carbonate dehydratase
AB849_009055	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AB849_009070	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
AB849_009080	ENOG4108ZCF	integral membrane protein
AB849_009090	ENOG4107QHF	type ii secretion system protein e
AB849_009095	ENOG4105D7Q	type ii secretion system
AB849_009130	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AB849_009135	ENOG4105WG9	Conserved Protein
AB849_009150	ENOG41073R8	VanW family
AB849_009155	ENOG41069ER	domain protein
AB849_009175	ENOG4105DB7	PHP domain protein
AB849_009180	ENOG41082BV	acetyltransferase
AB849_009185	ENOG4108ZMI	UPF0477 protein
AB849_009230	ENOG4107RHR	regulatoR
AB849_009240	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
AB849_009255	ENOG4105JHY	Membrane
AB849_009260	ENOG4107QSV	RmuC domain protein
AB849_009270	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AB849_009295	ENOG4105CXN	decarboxylase
AB849_009300	ENOG4108WQ8	UPF0637 protein
AB849_009310	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AB849_009315	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
AB849_009320	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
AB849_009325	ENOG4105QA2	
AB849_009345	ENOG4105C5X	domain protein
AB849_009350	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AB849_009355	ENOG4107QIV	Cytochrome c biogenesis protein
AB849_009365	ENOG4107YZP	Rhodanese domain protein
AB849_009370	ENOG4105C6T	cysteine synthase
AB849_009380	ENOG4105RKW	reductase (By
AB849_009390	ENOG4105E39	Enoyl-CoA hydratase
AB849_009400	ENOG4108YG3	N-acetyltransferase
AB849_009405	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AB849_009410	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
AB849_009415	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
AB849_009420	ENOG4105E39	Enoyl-CoA hydratase
AB849_009425	ENOG4107QX3	carboxylase
AB849_009430	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AB849_009440	ENOG41074B2	UPF0747 protein
AB849_009445	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AB849_009450	ENOG4108V6E	Cell division protein mraZ
AB849_009455	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AB849_009465	ENOG4105CJN	penicillin-binding protein
AB849_009470	ENOG4105CJN	penicillin-binding protein
AB849_009475	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AB849_009480	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
AB849_009485	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AB849_009490	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AB849_009495	ENOG4105CNI	cell division protein FtsW
AB849_009500	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AB849_009505	ENOG4105D4A	Cell wall formation (By similarity)
AB849_009510	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AB849_009520	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AB849_009525	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AB849_009530	ENOG4108AWX	Sporulation factor SpoIIGA 
AB849_009535	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AB849_009545	ENOG4105WR5	sporulation protein, YlmC YmxH family
AB849_009550	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AB849_009555	ENOG4105DFA	alanine racemase domain protein
AB849_009560	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
AB849_009570	ENOG4105DBK	s4 domain protein
AB849_009580	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AB849_009590	ENOG4105SCY	DNAK suppressor
AB849_009595	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AB849_009600	ENOG4105C34	Pseudouridine synthase
AB849_009605	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
AB849_009620	ENOG4105CD3	dihydroorotase
AB849_009630	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AB849_009635	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AB849_009640	ENOG4107XPQ	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AB849_009645	ENOG4105F23	Fibronectin-binding protein
AB849_009655	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AB849_009665	ENOG4107QYV	phosphohexose isomerase
AB849_009670	ENOG4105CN9	Peptidase m42 family protein
AB849_009675	ENOG4105CUB	amino acid
AB849_009685	ENOG4105DSJ	YicC domain protein
AB849_009690	ENOG4105KC4	UPF0296 protein
AB849_009695	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AB849_009700	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AB849_009705	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AB849_009710	ENOG4105C25	Primosomal protein n'
AB849_009715	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AB849_009720	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AB849_009725	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AB849_009730	ENOG4105E1K	spore germination protein
AB849_009745	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AB849_009750	ENOG4108ZF3	Phosphatase
AB849_009755	ENOG4105D9P	serine threonine protein kinase
AB849_009760	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AB849_009765	ENOG4105DJV	ribulose-phosphate 3-epimerase
AB849_009770	ENOG4105N67	Proton-coupled thiamine transporter YuaJ
AB849_009785	ENOG4105VB9	50S ribosomal protein l28
AB849_009790	ENOG4108ZAA	Alkaline-shock protein
AB849_009795	ENOG4105DP4	dak2 domain fusion protein ylov
AB849_009810	ENOG4105EJQ	L-serine dehydratase
AB849_009815	ENOG4105CB5	ATP-dependent DNA helicase recG
AB849_009830	ENOG4106H78	methyltransferase
AB849_009840	ENOG4105H20	Sporulation integral membrane protein YlbJ
AB849_009845	ENOG4105D78	K07001 NTE family protein
AB849_009850	ENOG41063PX	domain protein
AB849_009855	ENOG4105KNH	Nucleic acid-binding protein
AB849_009860	ENOG41067VY	50S ribosomal protein L32
AB849_009865	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
AB849_009870	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AB849_009880	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AB849_009885	ENOG4105CHR	reductase
AB849_009890	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AB849_009895	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AB849_009920	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AB849_009925	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AB849_009930	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
AB849_009940	ENOG4105K5M	30s ribosomal protein S16
AB849_009950	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AB849_009955	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AB849_009960	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AB849_009965	ENOG4105C3F	Signal peptidase i
AB849_009970	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
AB849_009975	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AB849_009980	ENOG4105VFF	UPF0102 protein
AB849_009985	ENOG4105C7B	Threonine dehydratase
AB849_009995	ENOG4105C0P	Mg chelatase subunit ChlI
AB849_010020	ENOG4107Y9E	nuclease
AB849_010030	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AB849_010035	ENOG4107QJT	sodium dicarboxylate symporter
AB849_010040	ENOG4108CCU	Ribonucleotide-diphosphate reductase subunit beta
AB849_010045	ENOG4105C0A	alcohol dehydrogenase
AB849_010050	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
AB849_010055	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AB849_010060	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AB849_010070	ENOG4105C85	amino acid
AB849_010080	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
AB849_010090	ENOG4105D4P	Coproporphyrinogen iii oxidase
AB849_010100	ENOG4105DFD	Na H antiporter
AB849_010125	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AB849_010130	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AB849_010135	ENOG4105C79	DNA protecting protein DprA
AB849_010140	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AB849_010145	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
AB849_010150	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AB849_010160	ENOG4105CE9	30S ribosomal protein S2
AB849_010165	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AB849_010170	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AB849_010175	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AB849_010180	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AB849_010185	ENOG4105KNE	Phosphatidate cytidylyltransferase
AB849_010190	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AB849_010195	ENOG4105DZP	Membrane-associated zinc metalloprotease
AB849_010200	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AB849_010245	ENOG4108IJ7	Glycine betaine
AB849_010255	ENOG4105CK1	PTS System
AB849_010260	ENOG4105VZJ	PTS System
AB849_010265	ENOG4105VCP	PTS System
AB849_010275	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
AB849_010285	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AB849_010290	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AB849_010300	ENOG4105E0X	reductase
AB849_010305	ENOG4105DPN	Oligoendopeptidase f
AB849_010320	ENOG4105CBC	glutamate synthase
AB849_010325	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AB849_010330	ENOG4105CHV	Transcription elongation factor NusA
AB849_010335	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
AB849_010340	ENOG4105VHM	ribosomal protein
AB849_010345	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AB849_010355	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AB849_010360	ENOG4105SFS	phosphoesterase RecJ domain protein
AB849_010365	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AB849_010375	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AB849_010380	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AB849_010390	ENOG4105C1V	Peptidase, M16
AB849_010395	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AB849_010410	ENOG4105E35	Dipicolinate synthase subunit A
AB849_010415	ENOG4108S0H	Dipicolinic acid synthetase, b subunit
AB849_010420	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AB849_010430	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AB849_010435	ENOG4105CN5	Metallo-Beta-Lactamase
AB849_010445	ENOG41068JE	domain protein
AB849_010460	ENOG4105KPY	Small multidrug resistance protein
AB849_010480	ENOG4105CMT	Dihydroxyacetone kinase
AB849_010485	ENOG4108UTZ	Dihydroxyacetone kinase
AB849_010490	ENOG4105VDH	Dihydroxyacetone kinase
AB849_010495	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
AB849_010505	ENOG4105CNU	cell division protein FtsK
AB849_010520	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
AB849_010525	ENOG4105XZV	Protein of unknown function (DUF3243)
AB849_010555	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AB849_010560	ENOG4105CEV	competence damage-inducible protein
AB849_010565	ENOG4105C1J	atp-dependent rna helicase
AB849_010570	ENOG4105VG1	fes assembly suf system protein
AB849_010575	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AB849_010580	ENOG410691R	Modulates RecA activity (By similarity)
AB849_010605	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
AB849_010610	ENOG4105D48	metallophosphoesterase
AB849_010615	ENOG4105MCT	stage V sporulation protein S
AB849_010620	ENOG4108IGT	Dipeptidase
AB849_010625	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
AB849_010630	ENOG4105DQU	oxidoreductase, subunit beta
AB849_010635	ENOG4108RQ5	Beta-lactamase domain-containing protein
AB849_010640	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
AB849_010645	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AB849_010665	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AB849_010670	ENOG4105EKQ	RNA-directed DNA polymerase
AB849_010675	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AB849_010680	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AB849_010685	ENOG4107YX5	Pfam:DUF548
AB849_010690	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AB849_010695	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AB849_010700	ENOG4106F1P	AAA ATPase, central domain protein
AB849_010705	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AB849_010710	ENOG4105CXI	aluminum resistance protein
AB849_010720	ENOG4105KV4	Transcriptional regulator
AB849_010725	ENOG4105C5F	glutamine synthetase
AB849_010735	ENOG4108Q3X	Transcriptional regulator
AB849_010750	ENOG4108K4B	hydrolase
AB849_010760	ENOG4107V6Q	Cyclic nucleotide-binding domain
AB849_010770	ENOG4105E2S	oxidase) subunit II
AB849_010775	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AB849_010780	ENOG4105CCU	oxidase (Subunit III)
AB849_010785	ENOG41060D1	Quinol oxidase
AB849_010790	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AB849_010800	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
AB849_010805	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AB849_010810	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
AB849_010820	ENOG4105VG1	fes assembly suf system protein
AB849_010850	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AB849_010855	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AB849_010860	ENOG4105C1Q	protoporphyrinogen oxidase
AB849_010865	ENOG4107JTW	chlorite dismutase
AB849_010885	ENOG4105C5S	asparaginyl-tRNA synthetase
AB849_010895	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AB849_010910	ENOG4108QY0	Membrane
AB849_010915	ENOG4107QW4	alcohol dehydrogenase
AB849_010925	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
AB849_010950	ENOG4105C59	p-type ATPase
AB849_010955	ENOG4105CGU	Enoyl-CoA hydratase
AB849_010965	ENOG4108IXY	short-chain dehydrogenase reductase
AB849_010985	ENOG4105TRT	Transcriptional regulator
AB849_010990	ENOG4105C26	Dehydrogenase
AB849_010995	ENOG4108JB8	alcohol dehydrogenase
AB849_011005	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
AB849_011010	ENOG4108DBC	nitroreductase
AB849_011015	ENOG4108U7W	acetyltransferase
AB849_011040	ENOG4105CE1	Ferrous iron transport protein b
AB849_011045	ENOG4105CE1	Ferrous iron transport protein b
AB849_011075	ENOG4105C72	UPF0176 protein
AB849_011090	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AB849_011095	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
AB849_011150	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
AB849_011170	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AB849_011185	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AB849_011225	ENOG4108IG5	Transcriptional regulator
AB849_011255	ENOG4105DVE	abc transporter atp-binding protein
AB849_011260	ENOG4105CMD	Transcriptional regulator, GntR family
AB849_011335	ENOG4105E7U	AraC family transcriptional regulator
AB849_011340	ENOG4105CAQ	asparagine synthetase
AB849_011385	ENOG4107TXC	Transcriptional regulator
AB849_011390	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AB849_011395	ENOG41076HS	cation diffusion facilitator family transporter
AB849_011420	ENOG4108SVB	resolvase
AB849_011430	ENOG41069ZX	
AB849_011445	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
AB849_011450	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
AB849_011455	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
AB849_011460	ENOG4108QCI	YvbH-like oligomerisation region
AB849_011480	ENOG41087NI	Sulfite exporter TauE/SafE
AB849_011505	ENOG4105PGM	cation diffusion facilitator family transporter
AB849_011510	ENOG4105CHR	reductase
AB849_011515	ENOG4105EU0	Major facilitator Superfamily
AB849_011520	ENOG4105EQN	UPF0261 protein
AB849_011540	ENOG4105C72	UPF0176 protein
AB849_011550	ENOG41060WC	Enoyl-CoA hydratase
AB849_011555	ENOG4105CHU	acetyl-coa acetyltransferase
AB849_011560	ENOG4105CHR	reductase
AB849_011565	ENOG4108IQE	Amp-dependent synthetase and ligase
AB849_011575	ENOG4105C1G	acyl-Coa dehydrogenase
AB849_011590	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AB849_011595	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AB849_011605	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AB849_011610	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AB849_011615	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AB849_011635	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AB849_011655	ENOG4107T0X	DNA ligase
AB849_011660	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AB849_011665	ENOG4105CE4	GlcNAc 6-P deacetylase
AB849_011670	ENOG4105DJ2	Major Facilitator Superfamily
AB849_011675	ENOG4107R7I	amino acid
AB849_011685	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AB849_011690	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AB849_011710	ENOG4107ZXU	DSBA oxidoreductase
AB849_011720	ENOG4105C85	amino acid
AB849_011735	ENOG41066VF	YeeE YedE family protein
AB849_011750	ENOG4105FDF	Could be involved in DNA repair (By similarity)
AB849_011765	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AB849_011770	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AB849_011775	ENOG4105D9N	nucleoside
AB849_011820	ENOG4105CPK	Glycosyl transferase (Group 1
AB849_011825	ENOG4105FJR	Lmbe family
AB849_011830	ENOG4105K6H	D-cysteine desulfhydrase
AB849_011840	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
AB849_011845	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
AB849_011870	ENOG4105PE6	Menaquinol-cytochrome c reductase, cytochrome b c subunit
AB849_011875	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AB849_011890	ENOG4108SXZ	UPF0302 protein
AB849_011905	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AB849_011915	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AB849_011920	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AB849_011925	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AB849_011930	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AB849_011935	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AB849_011940	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AB849_011945	ENOG4105CRQ	synthase (Component I)
AB849_011950	ENOG4105D49	3-dehydroquinate synthase
AB849_011955	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AB849_011960	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AB849_011980	ENOG4105XXQ	heptaprenyl diphosphate synthase component I
AB849_011990	ENOG4105WP2	Tryptophan RNA-binding attenuator protein
AB849_012000	ENOG4105EUJ	GTP cyclohydrolase i
AB849_012005	ENOG4105K70	DNA-binding protein
AB849_012010	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
AB849_012030	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AB849_012035	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AB849_012040	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AB849_012055	ENOG4105E9Q	Acyl-transferase
AB849_012060	ENOG4105CAT	Cytidine monophosphate kinase
AB849_012065	ENOG4105MSI	germination protein ypeb
AB849_012075	ENOG4107RB3	L-asparaginase
AB849_012080	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
AB849_012090	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
AB849_012110	ENOG4105C72	UPF0176 protein
AB849_012120	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
AB849_012130	ENOG4105ENA	helicase
AB849_012135	ENOG4105C5R	Aminotransferase
AB849_012140	ENOG4108JQ1	Dehydrogenase
AB849_012145	ENOG4105EMU	Dehydrogenase
AB849_012150	ENOG4105BZU	Histidine kinase
AB849_012155	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AB849_012160	ENOG4105CRE	cytochrome C
AB849_012165	ENOG4107TWT	Cytochrome c biogenesis protein
AB849_012170	ENOG4105FE9	pseudouridine synthase
AB849_012180	ENOG4108JIC	nucleoside recognition domain protein
AB849_012185	ENOG4105DZ1	carboxypeptidase
AB849_012190	ENOG4105KBJ	sporulation protein ytfj
AB849_012200	ENOG4105CTS	PTS system mannitol-specific
AB849_012205	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AB849_012210	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AB849_012215	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AB849_012220	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AB849_012225	ENOG4108R6K	riboflavin synthase, subunit alpha
AB849_012230	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AB849_012235	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
AB849_012255	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AB849_012260	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
AB849_012270	ENOG4105DZ1	carboxypeptidase
AB849_012285	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
AB849_012295	ENOG4105DCF	alanine dehydrogenase
AB849_012300	ENOG4105I3K	Ferric uptake regulator, Fur family
AB849_012305	ENOG4105MZ9	stage II sporulation protein m
AB849_012325	ENOG4105WEF	catalase
AB849_012345	ENOG4105EU9	
AB849_012350	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
AB849_012355	ENOG4108HNZ	carboxyl transferase
AB849_012360	ENOG4108ZVT	methylmalonyl-coA epimerase
AB849_012365	ENOG4105D5P	Methylmalonyl-coA mutase
AB849_012370	ENOG4105D5P	Methylmalonyl-coA mutase
AB849_012375	ENOG4105C7S	Dehydrogenase
AB849_012380	ENOG4105CPP	Dehydrogenase, E1 component
AB849_012395	ENOG4105CKM	Branched-chain carboxylic acid kinase
AB849_012405	ENOG4107RE7	phosphate butyryltransferase
AB849_012410	ENOG4108JUB	Transcriptional regulator
AB849_012415	ENOG4106CCJ	Protein of unknown function (DUF2627)
AB849_012420	ENOG4105EYF	MMPL domain protein
AB849_012430	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AB849_012440	ENOG4107QQR	Sporulation
AB849_012470	ENOG4105S1Z	Stage IV sporulation protein B
AB849_012475	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AB849_012480	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
AB849_012485	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AB849_012495	ENOG4105DX0	Hemolysin A
AB849_012500	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AB849_012505	ENOG4105CTB	Polyprenyl synthetase
AB849_012510	ENOG41084YM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AB849_012515	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AB849_012520	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AB849_012525	ENOG4105M7K	Involved in the transcription termination process (By similarity)
AB849_012530	ENOG4108ZSR	alkaline shock protein
AB849_012535	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AB849_012555	ENOG410644B	Stage III sporulation protein af
AB849_012565	ENOG4105KQ4	Stage iii sporulation protein ad
AB849_012570	ENOG4108CQH	stage III sporulation protein AC
AB849_012575	ENOG4105KR5	Stage iii sporulation protein
AB849_012580	ENOG4105CD2	stage iii sporulation protein aa
AB849_012590	ENOG4107RCC	Major Facilitator Superfamily
AB849_012600	ENOG4108VMM	UPF0756 membrane protein
AB849_012615	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AB849_012620	ENOG4105DC7	peptidase M24
AB849_012630	ENOG4105CBJ	Metal-dependent enzyme
AB849_012645	ENOG4105KST	dependent repressor
AB849_012650	ENOG4107YFT	Nadph-dependent fmn reductase
AB849_012660	ENOG4105C84	Histidine ammonia-lyase
AB849_012670	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AB849_012685	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
AB849_012700	ENOG4105CID	antiterminator
AB849_012710	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AB849_012715	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AB849_012720	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AB849_012725	ENOG4105C0D	helicase
AB849_012740	ENOG4105CDA	abc transporter atp-binding protein
AB849_012745	ENOG4105E5Q	amino acid AbC transporter
AB849_012750	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
AB849_012755	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AB849_012770	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
AB849_012775	ENOG41069DP	small acid-soluble spore protein
AB849_012780	ENOG4105BZ1	(ABC) transporter
AB849_012785	ENOG4105BZ1	(ABC) transporter
AB849_012790	ENOG4105CI3	gtp-binding protein typa
AB849_012795	ENOG4107XWI	flavin reductase domain protein, FMN-binding
AB849_012805	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
AB849_012815	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AB849_012820	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AB849_012835	ENOG4105CKP	Polysaccharide Biosynthesis Protein
AB849_012840	ENOG4108QY0	Membrane
AB849_012850	ENOG4105VIE	preprotein translocase, subunit YajC
AB849_012855	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AB849_012860	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AB849_012865	ENOG41061AI	Protein of unknown function (DUF2905)
AB849_012870	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AB849_012875	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AB849_012880	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AB849_012885	ENOG4105CDY	transcriptional regulatory protein
AB849_012890	ENOG4105C4K	Nad synthetase
AB849_012895	ENOG4105C4K	Nad synthetase
AB849_012915	ENOG4105CJ1	ABC, transporter
AB849_012925	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AB849_012930	ENOG4105CQC	Prephenate dehydratase
AB849_012935	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AB849_012940	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
AB849_012945	ENOG41090I5	UPF0735 ACT domain-containing protein
AB849_012950	ENOG4105KJF	protein tyrosine phosphatase
AB849_012960	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AB849_012970	ENOG4105K46	50S ribosomal protein l27
AB849_012975	ENOG4105X36	(ribosomal) protein
AB849_012980	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AB849_012995	ENOG4107QMS	site-determining protein
AB849_013000	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AB849_013020	ENOG4105DFF	Rod shape-determining protein mreb
AB849_013025	ENOG4105W5Q	DNA repair protein (RadC
AB849_013030	ENOG4108Z03	MAF-like protein
AB849_013040	ENOG4106A3R	peptidase
AB849_013050	ENOG4105CZX	twitching motility protein
AB849_013070	ENOG4105DFU	Cell wall formation (By similarity)
AB849_013075	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AB849_013080	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AB849_013090	ENOG41068KH	stage VI sporulation protein D
AB849_013095	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AB849_013100	ENOG4105D52	delta-aminolevulinic acid dehydratase
AB849_013110	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AB849_013115	ENOG4108Z73	Siroheme synthase
AB849_013125	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AB849_013130	ENOG4105D2X	ABC transporter substrate-binding protein
AB849_013140	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
AB849_013150	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AB849_013155	ENOG4105CPF	Cell wall formation (By similarity)
AB849_013160	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AB849_013170	ENOG4108IUQ	atp-dependent protease
AB849_013180	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AB849_013185	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AB849_013190	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation