locus-tag	class	description
TKV_c00010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
TKV_c00020	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
TKV_c00060	ENOG4105F1K	Glutamine amidotransferase
TKV_c00080	ENOG4108Z7R	Chaperone CsaA
TKV_c00090	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TKV_c00100	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TKV_c00110	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
TKV_c00120	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
TKV_c00130	ENOG4108ZP8	Acetolactate synthase small subunit
TKV_c00150	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
TKV_c00170	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TKV_c00180	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
TKV_c00190	ENOG4105C01	Dihydroxy-acid dehydratase
TKV_c00200	ENOG4105C7K	acetolactate synthase
TKV_c00210	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
TKV_c00220	ENOG4108R6K	riboflavin synthase, subunit alpha
TKV_c00240	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
TKV_c00250	ENOG4108REF	Sporulation integral membrane protein ytvi
TKV_c00270	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
TKV_c00300	ENOG4108KGH	TRANSCRIPTIONal
TKV_c00310	ENOG4105DJZ	UPF0182 protein
TKV_c00370	ENOG4105G6Z	alkaline phosphatase
TKV_c00390	ENOG4108Z6B	deaminase
TKV_c00460	ENOG4108K9K	Uncharacterised protein family (UPF0236)
TKV_c00470	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TKV_c00480	ENOG4105C6E	dna polymerase iii
TKV_c00490	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
TKV_c00500	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
TKV_c00510	ENOG4105WMR	Protein CrcB homolog
TKV_c00520	ENOG4105WMR	Protein CrcB homolog
TKV_c00530	ENOG4105DHT	Metal Dependent Phosphohydrolase
TKV_c00610	ENOG4105CHR	reductase
TKV_c00630	ENOG4105ETE	Transcriptional regulator (LacI family
TKV_c00640	ENOG4105XN3	extracellular solute-binding protein family 1
TKV_c00660	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
TKV_c00680	ENOG4105CKB	glycosidase
TKV_c00690	ENOG4105CKB	glycosidase
TKV_c00740	ENOG4108IG5	Transcriptional regulator
TKV_c00750	ENOG4105ECB	domain protein
TKV_c00760	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
TKV_c00770	ENOG4106DSS	Tartrate dehydratase subunit alpha
TKV_c00790	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
TKV_c00850	ENOG41084XP	SirA-like domain-containing protein
TKV_c00860	ENOG4105CUC	YeeE YedE family protein
TKV_c00900	ENOG4107QN2	dihydrolipoyl dehydrogenase
TKV_c00920	ENOG4105DKQ	ROK family
TKV_c00930	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TKV_c00950	ENOG4105CXN	decarboxylase
TKV_c00960	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
TKV_c00970	ENOG4105X0R	protein from nitrogen regulatory protein P-II
TKV_c00990	ENOG4107XK4	dna polymerase iii subunits gamma and tau
TKV_c01000	ENOG4105MA4	psp1 domain protein
TKV_c01040	ENOG4105CEU	Arginine dihydrolase
TKV_c01050	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
TKV_c01060	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
TKV_c01080	ENOG4105KRN	Transcriptional regulator, abrb family
TKV_c01090	ENOG4108JIC	nucleoside recognition domain protein
TKV_c01110	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
TKV_c01120	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
TKV_c01130	ENOG4105F8V	Hydrolase, tatD family
TKV_c01140	ENOG41069ER	domain protein
TKV_c01150	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
TKV_c01180	ENOG4105WJF	
TKV_c01190	ENOG4108WZW	RNA polymerase sigma
TKV_c01200	ENOG4105D1F	ATP-binding protein
TKV_c01220	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TKV_c01230	ENOG4105D65	subunit l
TKV_c01240	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
TKV_c01250	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
TKV_c01260	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TKV_c01270	ENOG4108XIB	electron transport protein ysaA
TKV_c01310	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
TKV_c01330	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
TKV_c01340	ENOG4107T0V	hydrogenase nickel incorporation protein HypB
TKV_c01380	ENOG4105CQS	hydrogenase expression formation protein HypD
TKV_c01420	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TKV_c01440	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
TKV_c01450	ENOG41082DI	50s ribosomal protein l31
TKV_c01460	ENOG4107104	thymidine kinase
TKV_c01470	ENOG4105CBJ	Metal-dependent enzyme
TKV_c01480	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
TKV_c01510	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TKV_c01520	ENOG4107WAU	Protein tyrosine phosphatase
TKV_c01530	ENOG4108YZG	isomerase
TKV_c01540	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
TKV_c01560	ENOG4105ESV	Glycosyl transferase, family 4
TKV_c01570	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
TKV_c01600	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
TKV_c01670	ENOG4108SHJ	s-layer protein
TKV_c01700	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
TKV_c01720	ENOG4108JQA	flagellar
TKV_c01730	ENOG4105CGA	flagellar basal-body rod protein FlgG
TKV_c01750	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
TKV_c01790	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
TKV_c01840	ENOG4105CZN	Potassium uptake protein
TKV_c01850	ENOG4107ZYR	domain protein
TKV_c01880	ENOG4105CNN	ABC, transporter
TKV_c01890	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
TKV_c01910	ENOG4105HEE	Binding Domain protein
TKV_c01920	ENOG4105CE4	GlcNAc 6-P deacetylase
TKV_c01930	ENOG4105CHM	Aminotransferase
TKV_c01940	ENOG4108ZB6	transcriptional regulator AsnC family
TKV_c01960	ENOG4105CE1	Ferrous iron transport protein b
TKV_c01970	ENOG4108JJB	ABC transporter
TKV_c01980	ENOG4108YZP	cobalt ABC transporter, inner membrane subunit CbiQ
TKV_c01990	ENOG4105G01	cobalamin (vitamin B12) biosynthesis CbiM protein
TKV_c02000	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
TKV_c02010	ENOG4105MRR	Transcriptional regulator (By similarity)
TKV_c02030	ENOG4105D9Q	decarboxylase (Beta subunit)
TKV_c02060	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
TKV_c02080	ENOG410624X	efflux transporter, rnd family, mfp subunit
TKV_c02090	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TKV_c02100	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TKV_c02120	ENOG4105ERH	Fumarylacetoacetate hydrolase
TKV_c02150	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
TKV_c02160	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
TKV_c02180	ENOG4105EYH	Exonuclease
TKV_c02200	ENOG4105C87	Aminotransferase class I and II
TKV_c02210	ENOG4105D3R	alkyl hydroperoxide reductase
TKV_c02250	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
TKV_c02260	ENOG4107QPH	glycogen) synthase
TKV_c02270	ENOG4107ZTW	SNARE associated Golgi
TKV_c02310	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
TKV_c02380	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
TKV_c02390	ENOG4107NFR	Fructose-1,6-bisphosphatase
TKV_c02400	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TKV_c02410	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TKV_c02430	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
TKV_c02440	ENOG4108K9K	Uncharacterised protein family (UPF0236)
TKV_c02450	ENOG4105DF9	Lipoate-protein, ligase
TKV_c02460	ENOG4107QN2	dihydrolipoyl dehydrogenase
TKV_c02490	ENOG4105CHM	Aminotransferase
TKV_c02600	ENOG4107QW4	alcohol dehydrogenase
TKV_c02640	ENOG4105MKU	Transcriptional regulator
TKV_c02670	ENOG4105CIZ	coA-substrate-specific enzyme activase
TKV_c02680	ENOG4105PGM	cation diffusion facilitator family transporter
TKV_c02700	ENOG4108T5I	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
TKV_c02710	ENOG4105C4B	ABC transporter, permease
TKV_c02720	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
TKV_c02740	ENOG4105C8T	Leucyl-tRNA synthetase
TKV_c02750	ENOG4108UMN	azlc family
TKV_c02770	ENOG4105DD7	kinase (PfkB family
TKV_c02780	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
TKV_c02790	ENOG41089WN	small, acid-soluble spore protein tlp
TKV_c02800	ENOG4105CJ3	phosphate transporter
TKV_c02820	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TKV_c02830	ENOG4105CTS	PTS system mannitol-specific
TKV_c02840	ENOG4105EMD	TRANSCRIPTIONal
TKV_c02870	ENOG4105CGH	5'-nucleotidase
TKV_c02880	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
TKV_c02910	ENOG4105FDK	ABC transporter
TKV_c02920	ENOG4105DSE	periplasmic solute binding protein
TKV_c02930	ENOG4105N80	Ferric uptake regulator, Fur family
TKV_c02940	ENOG4108V0P	LemA family
TKV_c02950	ENOG4105DUM	transcriptional regulator, lysR family
TKV_c02960	ENOG4105D5B	Sulfite reductase, subunit A
TKV_c02970	ENOG4107SHJ	sulfite reductase subunit b
TKV_c02980	ENOG410810Y	Sulfite reductase
TKV_c03010	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
TKV_c03090	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
TKV_c03100	ENOG4105EHG	Permease protein
TKV_c03110	ENOG4105E0A	ABC, transporter
TKV_c03120	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
TKV_c03130	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
TKV_c03170	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TKV_c03180	ENOG4108YZT	Adenosylcobinamide kinase
TKV_c03210	ENOG41081F0	Precorrin-8x methylmutase
TKV_c03240	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
TKV_c03250	ENOG4105DVK	Precorrin-2 c20-methyltransferase
TKV_c03260	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
TKV_c03270	ENOG4108P62	biosynthesis protein (CbiG)
TKV_c03280	ENOG4105E4R	Precorrin-3B C17-methyltransferase
TKV_c03290	ENOG4108JTQ	reductase
TKV_c03300	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
TKV_c03310	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
TKV_c03330	ENOG4105D52	delta-aminolevulinic acid dehydratase
TKV_c03340	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
TKV_c03370	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
TKV_c03380	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
TKV_c03410	ENOG4108JJB	ABC transporter
TKV_c03470	ENOG4108IUW	ABC transporter
TKV_c03540	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TKV_c03560	ENOG4105CJ1	ABC, transporter
TKV_c03590	ENOG4105DA5	(ABC) transporter
TKV_c03740	ENOG4105VJY	transcriptional regulator
TKV_c03810	ENOG4105CJ1	ABC, transporter
TKV_c03860	ENOG4108K9K	Uncharacterised protein family (UPF0236)
TKV_c03900	ENOG4107RBB	ABC transporter, permease
TKV_c03930	ENOG4105BZ1	(ABC) transporter
TKV_c03950	ENOG4107XWN	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
TKV_c03990	ENOG4108IUW	ABC transporter
TKV_c04000	ENOG4108SDH	ABC, transporter
TKV_c04080	ENOG4105WYW	fructose-bisphosphate aldolase
TKV_c04100	ENOG4107R39	(ABC) transporter
TKV_c04180	ENOG4105DA5	(ABC) transporter
TKV_c04220	ENOG4105CN9	Peptidase m42 family protein
TKV_c04230	ENOG4105CN9	Peptidase m42 family protein
TKV_c04240	ENOG4105CN9	Peptidase m42 family protein
TKV_c04290	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
TKV_c04350	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TKV_c04380	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
TKV_c04390	ENOG4105CI2	imidazolone-5-propionate hydrolase
TKV_c04400	ENOG4107TFB	basic membrane
TKV_c04410	ENOG4108JQ9	ABC transporter
TKV_c04420	ENOG4105UIB	(ABC) transporter
TKV_c04440	ENOG4105FDP	GntR family transcriptional regulator
TKV_c04460	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
TKV_c04510	ENOG4105C5Y	PTS System
TKV_c04530	ENOG4107SDT	Homocitrate synthase
TKV_c04550	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
TKV_c04570	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
TKV_c04590	ENOG41066UU	tRNA (Adenine-N1-)-methyltransferase
TKV_c04610	ENOG4105H67	Protein of unknown function (DUF421)
TKV_c04620	ENOG410667J	hydrolase
TKV_c04640	ENOG4105ETE	Transcriptional regulator (LacI family
TKV_c04650	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TKV_c04660	ENOG4105BZU	Histidine kinase
TKV_c04740	ENOG4108RAC	Rubrerythrin
TKV_c04750	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
TKV_c04760	ENOG4105C7H	Helicase, RecD TraA family
TKV_c04770	ENOG4105MJ2	Competence protein
TKV_c04810	ENOG4105E1Q	flagellar hook-associated protein
TKV_c04820	ENOG4105DTJ	flagellar hook-associated protein
TKV_c04840	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
TKV_c04850	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
TKV_c04900	ENOG4105CAQ	asparagine synthetase
TKV_c04930	ENOG4107RT6	flagellar hook-associated
TKV_c04940	ENOG4105MQ3	flagellar protein FliS
TKV_c04960	ENOG4105C8Q	Methyl-accepting chemotaxis
TKV_c04980	ENOG4108HW3	(ABC) transporter
TKV_c04990	ENOG4105E5Q	amino acid AbC transporter
TKV_c05030	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TKV_c05050	ENOG4108Z3G	3H domain protein
TKV_c05070	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
TKV_c05080	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
TKV_c05110	ENOG4105CTK	cobaltochelatase, cobn subunit
TKV_c05160	ENOG4105EET	magnesium chelatase
TKV_c05180	ENOG4105CJ1	ABC, transporter
TKV_c05200	ENOG4105E3A	(ABC) transporter
TKV_c05210	ENOG4105S10	periplasmic binding protein
TKV_c05230	ENOG4105EW6	flavin reductase domain protein, FMN-binding
TKV_c05240	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
TKV_c05260	ENOG4108U1V	ABC transporter, permease
TKV_c05270	ENOG4105E0A	ABC, transporter
TKV_c05290	ENOG4105CD3	dihydroorotase
TKV_c05310	ENOG4105DBV	ornithine carbamoyltransferase
TKV_c05320	ENOG4105C5B	carbamate kinase
TKV_c05330	ENOG4108SAX	Membrane
TKV_c05340	ENOG4105K8N	protein family UPF0079, ATPase
TKV_c05350	ENOG41072GX	Peptidase M22 Glycoprotease
TKV_c05370	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TKV_c05390	ENOG4105C5H	ABC transporter
TKV_c05400	ENOG4105E14	MotA TolQ exbB proton channel
TKV_c05410	ENOG4106VK6	Flagellar motor protein
TKV_c05440	ENOG4105DY9	regulatoR
TKV_c05450	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
TKV_c05490	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
TKV_c05520	ENOG4108Z03	MAF-like protein
TKV_c05530	ENOG4108UQV	Membrane
TKV_c05550	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TKV_c05610	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
TKV_c05640	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TKV_c05650	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TKV_c05660	ENOG4105C7N	Xanthine uracil vitamin C permease
TKV_c05670	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
TKV_c05680	ENOG4105C8V	SAICAR synthetase
TKV_c05690	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
TKV_c05700	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
TKV_c05710	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
TKV_c05730	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
TKV_c05740	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
TKV_c05760	ENOG4107QNG	Phosphoribosylglycinamide synthetase
TKV_c05770	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
TKV_c05780	ENOG4105CH2	amidohydrolase
TKV_c05800	ENOG4105CKP	Polysaccharide Biosynthesis Protein
TKV_c05820	ENOG4105ETD	TRANSCRIPTIONal
TKV_c05840	ENOG4105VZJ	PTS System
TKV_c05850	ENOG4105CK1	PTS System
TKV_c05860	ENOG4105VCP	PTS System
TKV_c05870	ENOG4105KGF	protein, YerC YecD
TKV_c05880	ENOG4105C4R	Atp-dependent dna helicase
TKV_c05900	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TKV_c05920	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TKV_c05930	ENOG4108J59	Extracellular solute-binding protein, family 5
TKV_c05940	ENOG4108J59	Extracellular solute-binding protein, family 5
TKV_c05950	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
TKV_c05960	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TKV_c05980	ENOG4108JQ7	(ABC) transporter
TKV_c06040	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
TKV_c06050	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
TKV_c06180	ENOG4105DM4	PTS System
TKV_c06190	ENOG4105DM4	PTS System
TKV_c06190	ENOG4105DM4	PTS System
TKV_c06200	ENOG4108YRF	PTS System
TKV_c06210	ENOG4108RE9	Phosphodiesterase
TKV_c06220	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
TKV_c06250	ENOG4105CP9	extracellular ligand-binding receptor
TKV_c06260	ENOG4105C32	Amino acid ABC transporter (Permease)
TKV_c06280	ENOG4105C0Z	ABC transporter
TKV_c06290	ENOG4108IV0	ABC, transporter
TKV_c06300	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
TKV_c06310	ENOG4108K9K	Uncharacterised protein family (UPF0236)
TKV_c06320	ENOG4108K9K	Uncharacterised protein family (UPF0236)
TKV_c06330	ENOG4108K9K	Uncharacterised protein family (UPF0236)
TKV_c06350	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
TKV_c06360	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
TKV_c06370	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
TKV_c06380	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
TKV_c06390	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
TKV_c06410	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
TKV_c06420	ENOG41082I9	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
TKV_c06430	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
TKV_c06440	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
TKV_c06450	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
TKV_c06460	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
TKV_c06470	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
TKV_c06480	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TKV_c06490	ENOG4105DWP	Membrane
TKV_c06510	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
TKV_c06630	ENOG4107QQG	Dehydrogenase
TKV_c06640	ENOG4105EPC	oxidoreductase
TKV_c06650	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
TKV_c06680	ENOG4108SHN	Glycosyl transferase, family 2
TKV_c06710	ENOG4108PQP	glycosyl transferase group 1
TKV_c06720	ENOG4105D3Q	Sugar transferase
TKV_c06740	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
TKV_c06760	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
TKV_c06790	ENOG4107QRT	dEAD DEAH box helicase
TKV_c06870	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
TKV_c06890	ENOG4105YB8	TM2 domain containing protein
TKV_c06940	ENOG4108V0P	LemA family
TKV_c06950	ENOG4108RE9	Phosphodiesterase
TKV_c07120	ENOG4105CY0	Metallo-Beta-Lactamase
TKV_c07130	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
TKV_c07140	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
TKV_c07150	ENOG4105CUB	amino acid
TKV_c07180	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
TKV_c07210	ENOG4107YJ4	chain length determinant protein
TKV_c07230	ENOG4108KGH	TRANSCRIPTIONal
TKV_c07240	ENOG4108K88	Membrane
TKV_c07280	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
TKV_c07290	ENOG41080V3	Major Facilitator superfamily
TKV_c07320	ENOG410841Q	phosphoesterase PA-phosphatase related protein
TKV_c07340	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
TKV_c07350	ENOG4108W8G	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP (By similarity)
TKV_c07360	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
TKV_c07370	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
TKV_c07380	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
TKV_c07400	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
TKV_c07450	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
TKV_c07460	ENOG4105C8M	UPF0272 protein
TKV_c07470	ENOG4105C8M	UPF0272 protein
TKV_c07480	ENOG4105BZU	Histidine kinase
TKV_c07490	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TKV_c07530	ENOG4105VKD	bioY protein
TKV_c07660	ENOG4105BZ8	glutamate synthase
TKV_c07730	ENOG4105D07	Signal peptide peptidase, SppA
TKV_c07770	ENOG4108IUW	ABC transporter
TKV_c07820	ENOG4105C84	Histidine ammonia-lyase
TKV_c07910	ENOG4108TYN	CAAX amino terminal protease family protein
TKV_c08020	ENOG4108MBX	Secretion Protein
TKV_c08040	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
TKV_c08060	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
TKV_c08080	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
TKV_c08090	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
TKV_c08240	ENOG4108IUZ	ABC transporter
TKV_c08280	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
TKV_c08290	ENOG4107KJX	Transcriptional regulator
TKV_c08320	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
TKV_c08330	ENOG4105DRS	transport system, permease
TKV_c08340	ENOG4107URF	beta-phospho-glucomutase
TKV_c08360	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
TKV_c08380	ENOG4105D06	uba thif-type nad fad binding protein
TKV_c08390	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
TKV_c08400	ENOG4105ETE	Transcriptional regulator (LacI family
TKV_c08460	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TKV_c08470	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TKV_c08510	ENOG4105F0V	Cell wall hydrolase
TKV_c08560	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
TKV_c08570	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
TKV_c08580	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
TKV_c08630	ENOG4105M3Z	response regulator
TKV_c08640	ENOG4105DYB	Isoaspartyl dipeptidase
TKV_c08650	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
TKV_c08670	ENOG4105DR5	peptidase
TKV_c08730	ENOG4105CJ1	ABC, transporter
TKV_c08750	ENOG4105D07	Signal peptide peptidase, SppA
TKV_c08800	ENOG4108UIC	UPF0340 protein
TKV_c08840	ENOG41067S9	phage shock protein C, PspC
TKV_c08850	ENOG4108ZJ4	polysaccharide deacetylase
TKV_c08860	ENOG4105C85	amino acid
TKV_c08900	ENOG4105DY9	regulatoR
TKV_c08910	ENOG4108HRK	Histidine kinase
TKV_c08920	ENOG4105EMN	RNA polymerase sigma factor
TKV_c08940	ENOG4105C2M	dna polymerase I
TKV_c08950	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
TKV_c08960	ENOG4105E4C	Lytic transglycosylase catalytic
TKV_c08990	ENOG4108VEU	Thiamine monophosphate synthase
TKV_c09020	ENOG4105K4H	Nlp p60 protein
TKV_c09040	ENOG4105E4C	Lytic transglycosylase catalytic
TKV_c09070	ENOG4108Z03	MAF-like protein
TKV_c09080	ENOG4105W5Q	DNA repair protein (RadC
TKV_c09090	ENOG4105DFF	Rod shape-determining protein mreb
TKV_c09130	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
TKV_c09140	ENOG4107QMS	site-determining protein
TKV_c09150	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
TKV_c09160	ENOG4105CNI	cell division protein FtsW
TKV_c09170	ENOG4108Z5K	methylglyoxal synthase
TKV_c09180	ENOG4105DR5	peptidase
TKV_c09220	ENOG4105C03	ribonuclease
TKV_c09230	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
TKV_c09240	ENOG410807C	QueT transporter
TKV_c09250	ENOG41067VP	Protein of unknown function (DUF1049)
TKV_c09260	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
TKV_c09280	ENOG4105K46	50S ribosomal protein l27
TKV_c09300	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TKV_c09310	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
TKV_c09320	ENOG4108WF2	Metal Dependent Phosphohydrolase
TKV_c09330	ENOG4108KGH	TRANSCRIPTIONal
TKV_c09340	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
TKV_c09380	ENOG4105CAQ	asparagine synthetase
TKV_c09390	ENOG4105DZ1	carboxypeptidase
TKV_c09400	ENOG4105KQC	Competence protein
TKV_c09420	ENOG4108W5N	phosphatidylglycerophosphatase a
TKV_c09480	ENOG4105CEY	Amp-dependent synthetase and ligase
TKV_c09520	ENOG4105DZS	Phenylacetate-CoA ligase
TKV_c09560	ENOG4105F8V	Hydrolase, tatD family
TKV_c09630	ENOG4105CM2	brancheD-chain amino acid aminotransferase
TKV_c09690	ENOG4105CTK	cobaltochelatase, cobn subunit
TKV_c09700	ENOG4105G01	cobalamin (vitamin B12) biosynthesis CbiM protein
TKV_c09720	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TKV_c09730	ENOG4105BZU	Histidine kinase
TKV_c09750	ENOG4105PUK	Membrane
TKV_c09780	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
TKV_c09800	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
TKV_c09820	ENOG4105CEF	Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity)
TKV_c09870	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
TKV_c09880	ENOG4105CSA	Coproporphyrinogen iii oxidase
TKV_c09890	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
TKV_c09900	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TKV_c09910	ENOG4105CFG	Acts as a chaperone (By similarity)
TKV_c09920	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
TKV_c09930	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
TKV_c09940	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
TKV_c09950	ENOG4105VUC	UPF0237 protein
TKV_c09970	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TKV_c09980	ENOG4107YU2	histidine triad (hIT) protein
TKV_c09990	ENOG4105VCC	30S ribosomal protein S21
TKV_c10010	ENOG41068P3	sporulation protein YqfC
TKV_c10030	ENOG4105C9A	Phoh family
TKV_c10040	ENOG4105CTJ	Metal Dependent Phosphohydrolase
TKV_c10050	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
TKV_c10070	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
TKV_c10100	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
TKV_c10130	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
TKV_c10150	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
TKV_c10160	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
TKV_c10180	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
TKV_c10210	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
TKV_c10220	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TKV_c10240	ENOG4108JQ7	(ABC) transporter
TKV_c10280	ENOG4105CTK	cobaltochelatase, cobn subunit
TKV_c10290	ENOG4105DEF	Extracellular solute-binding protein, family 5
TKV_c10300	ENOG4105CTK	cobaltochelatase, cobn subunit
TKV_c10310	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TKV_c10360	ENOG41080XS	Cobyrinic acid ac-diamide synthase
TKV_c10380	ENOG4105DUM	transcriptional regulator, lysR family
TKV_c10400	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
TKV_c10410	ENOG4107S9D	Alpha beta hydrolase
TKV_c10450	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
TKV_c10480	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
TKV_c10490	ENOG41067KS	pro-sigma K processing
TKV_c10500	ENOG41066FP	Small acid-soluble spore protein I
TKV_c10510	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
TKV_c10520	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
TKV_c10550	ENOG4105CJ1	ABC, transporter
TKV_c10570	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TKV_c10640	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
TKV_c10690	ENOG4105CND	Glycosyl transferase, family 2
TKV_c10740	ENOG4108UXE	Protein tyrosine phosphatase
TKV_c10760	ENOG4108HQ0	Exopolysaccharide biosynthesis protein
TKV_c10820	ENOG4105EJQ	L-serine dehydratase
TKV_c10830	ENOG4105DPN	Oligoendopeptidase f
TKV_c10840	ENOG4105D49	3-dehydroquinate synthase
TKV_c10850	ENOG4105CQC	Prephenate dehydratase
TKV_c10860	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
TKV_c10870	ENOG4105EVN	Prephenate dehydrogenase
TKV_c10880	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
TKV_c10890	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TKV_c10900	ENOG4105GR3	Histidine kinase
TKV_c10940	ENOG41066F8	ROK family
TKV_c10960	ENOG4105K63	Thioredoxin
TKV_c10970	ENOG4105CXN	decarboxylase
TKV_c11020	ENOG4108IUM	Glycogen debranching enzyme
TKV_c11040	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
TKV_c11060	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
TKV_c11110	ENOG4105D41	biosynthesis protein thiH
TKV_c11160	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
TKV_c11190	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
TKV_c11240	ENOG4105C6T	cysteine synthase
TKV_c11250	ENOG4105CDY	transcriptional regulatory protein
TKV_c11260	ENOG4108V3W	Chemotaxis protein, CheW
TKV_c11280	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
TKV_c11290	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
TKV_c11300	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
TKV_c11320	ENOG4105JFG	SpoIID LytB domain protein
TKV_c11350	ENOG4105BZU	Histidine kinase
TKV_c11400	ENOG4108Z0R	Transferase
TKV_c11410	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TKV_c11420	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TKV_c11440	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
TKV_c11450	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
TKV_c11460	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
TKV_c11480	ENOG4105C5X	domain protein
TKV_c11510	ENOG4105C9M	aspartyl-trna synthetase
TKV_c11520	ENOG4105CUZ	uba thif-type nad fad binding protein
TKV_c11530	ENOG4105VPX	protein, conserved in bacteria
TKV_c11540	ENOG4105K63	Thioredoxin
TKV_c11580	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
TKV_c11600	ENOG4105C02	permease
TKV_c11610	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TKV_c11620	ENOG4105VBH	UPF0297 protein
TKV_c11630	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
TKV_c11650	ENOG4105I3K	Ferric uptake regulator, Fur family
TKV_c11660	ENOG4105CN5	Metallo-Beta-Lactamase
TKV_c11670	ENOG41084CE	UPF0342 protein
TKV_c11680	ENOG410807C	QueT transporter
TKV_c11690	ENOG4105HHA	aminodeoxychorismate lyase
TKV_c11700	ENOG4108VQJ	O-methyltransferase
TKV_c11710	ENOG4105CFP	Peptidase U32
TKV_c11720	ENOG4105CJN	penicillin-binding protein
TKV_c11730	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TKV_c11740	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
TKV_c11750	ENOG4105E2X	shikimate dehydrogenase
TKV_c11760	ENOG4107QHF	type ii secretion system protein e
TKV_c11770	ENOG4105CZX	twitching motility protein
TKV_c11790	ENOG4108VAU	general secretion pathway protein G
TKV_c11910	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
TKV_c11920	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
TKV_c11930	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
TKV_c11940	ENOG4105DC7	peptidase M24
TKV_c11950	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
TKV_c11970	ENOG4105CD2	stage iii sporulation protein aa
TKV_c11990	ENOG4108CQH	stage III sporulation protein AC
TKV_c12000	ENOG4105KQ4	Stage iii sporulation protein ad
TKV_c12020	ENOG410644B	Stage III sporulation protein af
TKV_c12050	ENOG4108ZSR	alkaline shock protein
TKV_c12080	ENOG4105M7K	Involved in the transcription termination process (By similarity)
TKV_c12090	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
TKV_c12100	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
TKV_c12140	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
TKV_c12150	ENOG4105DX0	Hemolysin A
TKV_c12160	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
TKV_c12170	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
TKV_c12180	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
TKV_c12190	ENOG4105S1Z	Stage IV sporulation protein B
TKV_c12200	ENOG4107QQR	Sporulation
TKV_c12210	ENOG4108K9K	Uncharacterised protein family (UPF0236)
TKV_c12330	ENOG4105MZ9	stage II sporulation protein m
TKV_c12340	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TKV_c12350	ENOG4105DZ1	carboxypeptidase
TKV_c12370	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
TKV_c12380	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TKV_c12390	ENOG41084UG	Pfam:DUF1458
TKV_c12400	ENOG41090VF	Stage v sporulation protein ac
TKV_c12430	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
TKV_c12440	ENOG4108Z4T	Peptidase M50
TKV_c12450	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
TKV_c12460	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
TKV_c12470	ENOG4105PTM	secreted protein
TKV_c12490	ENOG4105KBJ	sporulation protein ytfj
TKV_c12510	ENOG4105DZ1	carboxypeptidase
TKV_c12530	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
TKV_c12540	ENOG4105FE9	pseudouridine synthase
TKV_c12560	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
TKV_c12570	ENOG4105CYW	agmatinase
TKV_c12580	ENOG4107QSA	Oxaloacetate decarboxylase
TKV_c12610	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
TKV_c12620	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
TKV_c12650	ENOG4105CBX	hi0933 family
TKV_c12670	ENOG4105CAT	Cytidine monophosphate kinase
TKV_c12690	ENOG4108IUH	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
TKV_c12700	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
TKV_c12710	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
TKV_c12720	ENOG4105BZU	Histidine kinase
TKV_c12740	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
TKV_c12750	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
TKV_c12760	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
TKV_c12770	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
TKV_c12780	ENOG4105II7	pyrroline-5-carboxylate reductase
TKV_c12790	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TKV_c12800	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TKV_c12810	ENOG4105CXI	aluminum resistance protein
TKV_c12820	ENOG4106F1P	AAA ATPase, central domain protein
TKV_c12830	ENOG4105C83	adenylosuccinate lyase
TKV_c12860	ENOG4105MCT	stage V sporulation protein S
TKV_c12870	ENOG4105D48	metallophosphoesterase
TKV_c12900	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
TKV_c12910	ENOG410902V	Modulates RecA activity (By similarity)
TKV_c12920	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
TKV_c12930	ENOG4105CEV	competence damage-inducible protein
TKV_c12940	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
TKV_c12950	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
TKV_c12960	ENOG4105CNU	cell division protein FtsK
TKV_c12980	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
TKV_c13010	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
TKV_c13020	ENOG4105C1V	Peptidase, M16
TKV_c13040	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TKV_c13050	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
TKV_c13060	ENOG4105DTN	riboflavin biosynthesis protein ribF
TKV_c13070	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
TKV_c13080	ENOG4107U2Z	DHH family
TKV_c13090	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
TKV_c13120	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
TKV_c13130	ENOG4105CHV	Transcription elongation factor NusA
TKV_c13140	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
TKV_c13150	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
TKV_c13170	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
TKV_c13180	ENOG4105DZP	Membrane-associated zinc metalloprotease
TKV_c13210	ENOG4105DZP	Membrane-associated zinc metalloprotease
TKV_c13220	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
TKV_c13230	ENOG4105KNE	Phosphatidate cytidylyltransferase
TKV_c13240	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
TKV_c13260	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
TKV_c13270	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
TKV_c13280	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
TKV_c13290	ENOG4105CE9	30S ribosomal protein S2
TKV_c13320	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TKV_c13330	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
TKV_c13350	ENOG4108V3W	Chemotaxis protein, CheW
TKV_c13360	ENOG4105CBS	Chea signal transduction histidine kinase
TKV_c13370	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
TKV_c13400	ENOG4105FZW	flagellar biosynthesis regulator FlhF
TKV_c13410	ENOG4105D7B	Flagellar biosynthesis protein flha
TKV_c13420	ENOG4105D00	flagellar biosynthetic protein flhB
TKV_c13430	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
TKV_c13440	ENOG4105VS8	Flagellar biosynthetic protein fliq
TKV_c13450	ENOG4105CN7	Flagellar biosynthetic protein FliP
TKV_c13460	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
TKV_c13480	ENOG41068WV	flagellar FlbD family protein
TKV_c13490	ENOG4105BZE	flagellar hook protein, FlgE
TKV_c13510	ENOG410822I	Flagellar hook capping protein
TKV_c13570	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
TKV_c13580	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
TKV_c13590	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
TKV_c13600	ENOG4108ZC9	flagellar basal-body rod protein flgc
TKV_c13610	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
TKV_c13620	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
TKV_c13630	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
TKV_c13640	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
TKV_c13650	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
TKV_c13660	ENOG4105C79	DNA protecting protein DprA
TKV_c13670	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TKV_c13680	ENOG4105VFF	UPF0102 protein
TKV_c13690	ENOG4105C31	Tryptophanyl-tRNA synthetase
TKV_c13700	ENOG4108JYZ	YitT family
TKV_c13710	ENOG4105C0P	Mg chelatase subunit ChlI
TKV_c13720	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
TKV_c13730	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
TKV_c13740	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
TKV_c13750	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
TKV_c13760	ENOG4105VB6	UPF0109 protein
TKV_c13770	ENOG4105K5M	30s ribosomal protein S16
TKV_c13800	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
TKV_c13810	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
TKV_c13830	ENOG4105MCT	stage V sporulation protein S
TKV_c13850	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
TKV_c13860	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
TKV_c13870	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
TKV_c13880	ENOG4105CHR	reductase
TKV_c13890	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
TKV_c13900	ENOG4105EA8	2-Nitropropane dioxygenase
TKV_c13910	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
TKV_c13930	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
TKV_c13940	ENOG41067VY	50S ribosomal protein L32
TKV_c13960	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
TKV_c13970	ENOG4108IJ2	phosphate acetyltransferase
TKV_c13990	ENOG4105H20	Sporulation integral membrane protein YlbJ
TKV_c14010	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
TKV_c14020	ENOG4106H78	methyltransferase
TKV_c14050	ENOG4105EPR	degv family
TKV_c14060	ENOG4105CB5	ATP-dependent DNA helicase recG
TKV_c14070	ENOG4105DP4	dak2 domain fusion protein ylov
TKV_c14080	ENOG4108ZSR	alkaline shock protein
TKV_c14120	ENOG4105DJV	ribulose-phosphate 3-epimerase
TKV_c14130	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
TKV_c14140	ENOG4105D9P	serine threonine protein kinase
TKV_c14150	ENOG4108ZF3	Phosphatase
TKV_c14160	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
TKV_c14170	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TKV_c14200	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
TKV_c14210	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
TKV_c14220	ENOG4105C25	Primosomal protein n'
TKV_c14230	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
TKV_c14240	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
TKV_c14260	ENOG4105DSJ	YicC domain protein
TKV_c14270	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
TKV_c14280	ENOG4105C6X	Major Facilitator
TKV_c14300	ENOG4105F23	Fibronectin-binding protein
TKV_c14350	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
TKV_c14360	ENOG4105DR4	Methyltransferase
TKV_c14380	ENOG4107XPQ	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
TKV_c14400	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
TKV_c14420	ENOG4105CD3	dihydroorotase
TKV_c14430	ENOG4105CXT	aspartate transcarbamylase
TKV_c14440	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
TKV_c14450	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
TKV_c14460	ENOG4105C34	Pseudouridine synthase
TKV_c14470	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
TKV_c14480	ENOG4105KNA	-acetyltransferase
TKV_c14530	ENOG4107QMH	DNA methylase
TKV_c14550	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
TKV_c14620	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
TKV_c14720	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
TKV_c14780	ENOG41067S9	phage shock protein C, PspC
TKV_c14820	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TKV_c14830	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
TKV_c14870	ENOG4105DK0	Indole-3-glycerol phosphate synthase
TKV_c14880	ENOG4108I0Q	anthranilate phosphoribosyltransferase
TKV_c14890	ENOG4105DDQ	anthranilate synthase
TKV_c14900	ENOG4105CRQ	synthase (Component I)
TKV_c14920	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
TKV_c14930	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
TKV_c14960	ENOG4105DBK	s4 domain protein
TKV_c14980	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
TKV_c14990	ENOG4105DFA	alanine racemase domain protein
TKV_c15010	ENOG4105C0F	tryptophanase EC 4.1.99.1
TKV_c15020	ENOG4105KME	endoribonuclease L-psp
TKV_c15060	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
TKV_c15070	ENOG4108IYU	L-aspartate oxidase
TKV_c15080	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
TKV_c15120	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
TKV_c15150	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
TKV_c15200	ENOG4105S2F	
TKV_c15230	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
TKV_c15240	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
TKV_c15250	ENOG4105E2Z	phosphate ABC transporter (Permease
TKV_c15260	ENOG4105C8U	phosphate abc transporter
TKV_c15280	ENOG4105CVA	phosphate
TKV_c15290	ENOG4105BZU	Histidine kinase
TKV_c15300	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
TKV_c15310	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
TKV_c15320	ENOG4108BIK	prc-barrel domain-containing protein
TKV_c15330	ENOG4105E65	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TKV_c15340	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TKV_c15350	ENOG4105FFI	sigma-e processing peptidase spoiiga
TKV_c15360	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
TKV_c15370	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
TKV_c15380	ENOG4105K67	small basic protein
TKV_c15400	ENOG4108UFP	Essential cell division protein (By similarity)
TKV_c15410	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
TKV_c15420	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
TKV_c15430	ENOG4105CNI	cell division protein FtsW
TKV_c15450	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
TKV_c15460	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
TKV_c15470	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
TKV_c15480	ENOG4105CJN	penicillin-binding protein
TKV_c15550	ENOG4105C3G	gtp-binding protein
TKV_c15620	ENOG4108YZ8	Superoxide reductase
TKV_c15640	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
TKV_c15660	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
TKV_c15670	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
TKV_c15710	ENOG4105K4I	Scp-like extracellular
TKV_c15720	ENOG4105DFM	M18 family aminopeptidase
TKV_c15730	ENOG4105WH1	Two component transcriptional regulator luxr family
TKV_c15770	ENOG4105EWC	Purine nucleoside phosphorylase
TKV_c15780	ENOG4105C98	muts2 protein
TKV_c15790	ENOG4105CFP	Peptidase U32
TKV_c15840	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
TKV_c15850	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
TKV_c15860	ENOG4108RWN	rrna methyltransferase
TKV_c15870	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
TKV_c15880	ENOG4105VJV	50s ribosomal protein L35
TKV_c15890	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
TKV_c15900	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
TKV_c15920	ENOG4105C22	threonyL-tRNA synthetase
TKV_c15930	ENOG4108UH6	UPF0754 membrane protein
TKV_c15960	ENOG41065U4	response regulator
TKV_c15970	ENOG4105XXY	Thioredoxin
TKV_c16050	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
TKV_c16060	ENOG4105VEQ	Cold shock protein
TKV_c16070	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
TKV_c16100	ENOG41083MR	nifu domain-containing protein
TKV_c16120	ENOG4108ZGC	gaf domain protein
TKV_c16140	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
TKV_c16160	ENOG4107QSE	Dipeptidase
TKV_c16180	ENOG4105DG6	mannose-6-phosphate isomerase
TKV_c16190	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
TKV_c16220	ENOG4105EGD	dinuclear metal center protein, YbgI family
TKV_c16260	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TKV_c16270	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
TKV_c16280	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
TKV_c16290	ENOG4105XZU	Preprotein translocase, subunit SecG
TKV_c16310	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
TKV_c16330	ENOG4105BZA	Phosphoglycerate kinase
TKV_c16360	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TKV_c16370	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
TKV_c16390	ENOG4105G5W	regulator Fur family
TKV_c16400	ENOG41073R8	VanW family
TKV_c16410	ENOG4105CSM	endonuclease III
TKV_c16420	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
TKV_c16430	ENOG4105DAN	ATP-dependent protease
TKV_c16450	ENOG410688J	Ferredoxin
TKV_c16480	ENOG4105E0A	ABC, transporter
TKV_c16490	ENOG4105EET	magnesium chelatase
TKV_c16550	ENOG4105E3A	(ABC) transporter
TKV_c16560	ENOG4105CJ1	ABC, transporter
TKV_c16570	ENOG4105CTK	cobaltochelatase, cobn subunit
TKV_c16590	ENOG4105C22	threonyL-tRNA synthetase
TKV_c16610	ENOG4105EMS	pseudouridine synthase
TKV_c16640	ENOG4105D1H	recombination factor protein RarA
TKV_c16700	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TKV_c16730	ENOG4105WEF	catalase
TKV_c16740	ENOG4108UIN	ybak prolyl-trna synthetase associated region
TKV_c16750	ENOG4105C3R	Methionine synthase
TKV_c16770	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
TKV_c16780	ENOG4107QYV	phosphohexose isomerase
TKV_c16790	ENOG4108RCM	Nitroreductase
TKV_c16800	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
TKV_c16820	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
TKV_c16830	ENOG4105UQX	Mate efflux family protein
TKV_c16870	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TKV_c16900	ENOG4105CTQ	phosphohexokinase
TKV_c16920	ENOG4105C0B	DNA polymerase III (alpha subunit)
TKV_c16940	ENOG4105KRI	phosphocarrier protein (HPr
TKV_c16950	ENOG4105CIE	May be required for sporulation (By similarity)
TKV_c16970	ENOG4108IUK	alpha amylase, catalytic
TKV_c17010	ENOG4105EG2	ABC transporter, permease
TKV_c17020	ENOG4108K9K	Uncharacterised protein family (UPF0236)
TKV_c17040	ENOG4105D56	permease protein
TKV_c17050	ENOG4107FKK	extracellular solute-binding protein family 1
TKV_c17100	ENOG4105D4A	Cell wall formation (By similarity)
TKV_c17130	ENOG4105D78	K07001 NTE family protein
TKV_c17140	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
TKV_c17190	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
TKV_c17200	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TKV_c17220	ENOG4105C59	p-type ATPase
TKV_c17240	ENOG41082MP	copper ion binding protein
TKV_c17250	ENOG4105DQR	SNARE associated Golgi
TKV_c17280	ENOG4105BZU	Histidine kinase
TKV_c17310	ENOG4105G5W	regulator Fur family
TKV_c17330	ENOG4105G15	CRISPR-associated RAMP protein, Csm5 family
TKV_c17350	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
TKV_c17430	ENOG4108HWH	(ABC) transporter
TKV_c17440	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
TKV_c17490	ENOG4107QW8	radical SAM domain protein
TKV_c17530	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
TKV_c17570	ENOG41080TK	Universal stress protein
TKV_c17620	ENOG4108JVH	Protein of unknown function DUF43
TKV_c17710	ENOG4105CJN	penicillin-binding protein
TKV_c17770	ENOG4105CMR	udp-glucose 4-epimerase
TKV_c17780	ENOG4105C5I	Dehydrogenase
TKV_c17820	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
TKV_c17880	ENOG4105NBF	ammecr1 domain protein
TKV_c17900	ENOG4105CEY	Amp-dependent synthetase and ligase
TKV_c17930	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
TKV_c17960	ENOG4105CJN	penicillin-binding protein
TKV_c17990	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
TKV_c18000	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
TKV_c18010	ENOG4108N5B	2-phosphosulfolactate phosphatase
TKV_c18040	ENOG4105DR5	peptidase
TKV_c18050	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
TKV_c18060	ENOG4105CAK	Cell division ATP-binding protein ftsE
TKV_c18070	ENOG4107VHA	regulatoR
TKV_c18100	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
TKV_c18110	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
TKV_c18130	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
TKV_c18160	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
TKV_c18240	ENOG4105CFG	Acts as a chaperone (By similarity)
TKV_c18320	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
TKV_c18330	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
TKV_c18340	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
TKV_c18380	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
TKV_c18390	ENOG4108IGT	Dipeptidase
TKV_c18410	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
TKV_c18440	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
TKV_c18450	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
TKV_c18470	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
TKV_c18480	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
TKV_c18570	ENOG4105CJ1	ABC, transporter
TKV_c18580	ENOG4105E2V	Glycosyltransferase 36
TKV_c18590	ENOG4105D7N	magnesium and cobalt transport protein CorA
TKV_c18600	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TKV_c18620	ENOG4105DWV	Homoserine O-trans-acetylase
TKV_c18640	ENOG4105D6E	homoserine dehydrogenase
TKV_c18670	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TKV_c18690	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
TKV_c18700	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
TKV_c18710	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
TKV_c18770	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TKV_c18810	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
TKV_c18840	ENOG4108HHA	Transketolase
TKV_c18850	ENOG4108JYZ	YitT family
TKV_c18900	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
TKV_c18920	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
TKV_c18940	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
TKV_c18950	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
TKV_c19030	ENOG4105FDF	Could be involved in DNA repair (By similarity)
TKV_c19040	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
TKV_c19050	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
TKV_c19100	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
TKV_c19200	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TKV_c19220	ENOG4105CEY	Amp-dependent synthetase and ligase
TKV_c19250	ENOG4107RE7	phosphate butyryltransferase
TKV_c19310	ENOG4105CKM	Branched-chain carboxylic acid kinase
TKV_c19320	ENOG4107RDP	Dehydrogenase
TKV_c19330	ENOG4107RE7	phosphate butyryltransferase
TKV_c19340	ENOG4105CKM	Branched-chain carboxylic acid kinase
TKV_c19360	ENOG4105C8B	TIGR00159 family
TKV_c19480	ENOG4107SMJ	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
TKV_c19570	ENOG4105DUM	transcriptional regulator, lysR family
TKV_c19580	ENOG4107QHI	-hydrogenase
TKV_c19590	ENOG4107QIZ	NADH dehydrogenase
TKV_c19600	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
TKV_c19610	ENOG4105MRR	Transcriptional regulator (By similarity)
TKV_c19620	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
TKV_c19630	ENOG4105CRQ	synthase (Component I)
TKV_c19660	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
TKV_c19670	ENOG4105JZC	GHMP kinase
TKV_c19680	ENOG41084C4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
TKV_c19690	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
TKV_c19700	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
TKV_c19710	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TKV_c19720	ENOG4105C8S	subunit m
TKV_c19740	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
TKV_c19750	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TKV_c19810	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
TKV_c19820	ENOG4105E8X	CO dehydrogenase acetyl-CoA synthase complex beta subunit
TKV_c19840	ENOG4105EYX	Acetyl-CoA decarbonylase synthase complex subunit gamma
TKV_c19850	ENOG4106HYN	CO dehydrogenase acetyl-CoA synthase delta subunit
TKV_c19880	ENOG4105SYT	Methylenetetrahydrofolate reductase
TKV_c19900	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
TKV_c19910	ENOG410908R	Methenyltetrahydrofolate cyclohydrolase
TKV_c19930	ENOG4105CKU	formyltetrahydrofolate synthetase
TKV_c19940	ENOG4105TMB	Formate nitrite transporter
TKV_c19950	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
TKV_c19960	ENOG4107QHI	-hydrogenase
TKV_c19970	ENOG4108RC0	Electron transport protein
TKV_c19980	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
TKV_c19990	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
TKV_c20000	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
TKV_c20020	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TKV_c20060	ENOG4105CKU	formyltetrahydrofolate synthetase
TKV_c20070	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
TKV_c20080	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
TKV_c20090	ENOG41080XS	Cobyrinic acid ac-diamide synthase
TKV_c20100	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
TKV_c20110	ENOG4108R8B	oxidoreductase Fe-S subunit
TKV_c20220	ENOG4108UJD	30S ribosomal protein S9
TKV_c20230	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
TKV_c20240	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
TKV_c20250	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
TKV_c20260	ENOG4108JJB	ABC transporter
TKV_c20270	ENOG4108JJB	ABC transporter
TKV_c20280	ENOG4108ZT0	50S ribosomal protein l17
TKV_c20290	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TKV_c20300	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
TKV_c20310	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
TKV_c20320	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TKV_c20340	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
TKV_c20370	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
TKV_c20380	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
TKV_c20390	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
TKV_c20400	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
TKV_c20410	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
TKV_c20430	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
TKV_c20440	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
TKV_c20450	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TKV_c20460	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
TKV_c20470	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
TKV_c20480	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
TKV_c20490	ENOG41082SA	50s ribosomal protein l29
TKV_c20510	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
TKV_c20520	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
TKV_c20530	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
TKV_c20540	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TKV_c20550	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
TKV_c20560	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
TKV_c20570	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
TKV_c20580	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
TKV_c20590	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TKV_c20600	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TKV_c20610	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
TKV_c20620	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
TKV_c20630	ENOG4105XPM	ribosomal protein
TKV_c20640	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TKV_c20650	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TKV_c20660	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
TKV_c20680	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
TKV_c20690	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
TKV_c20700	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
TKV_c20710	ENOG410683Z	Preprotein translocase SecE subunit
TKV_c20720	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TKV_c20750	ENOG4105M0M	Tetracycline resistance protein
TKV_c20760	ENOG4105C2N	RNA methyltransferase TrmH family group 3
TKV_c20780	ENOG4105C8N	cysteinyl-tRNA synthetase
TKV_c20790	ENOG4105D7W	serine acetyltransferase
TKV_c20830	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
TKV_c20850	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
TKV_c20860	ENOG4105CTP	PilT protein domain protein
TKV_c20880	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
TKV_c20890	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
TKV_c20900	ENOG4105KST	dependent repressor
TKV_c20920	ENOG41066A3	ATP guanido phosphotransferase
TKV_c20930	ENOG4108Z0C	Uvrb UvrC protein
TKV_c20960	ENOG4105C6K	Malic enzyme
TKV_c20970	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TKV_c20980	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
TKV_c20990	ENOG4105BZU	Histidine kinase
TKV_c21030	ENOG410867B	UPF0291 protein
TKV_c21080	ENOG4105PW4	Sugar fermentation stimulation protein homolog
TKV_c21090	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
TKV_c21100	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TKV_c21110	ENOG4105EEI	dihydropteroate synthase
TKV_c21120	ENOG4105EUJ	GTP cyclohydrolase i
TKV_c21130	ENOG4105CRK	lysyL-tRNA synthetase
TKV_c21140	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
TKV_c21210	ENOG4105E1K	spore germination protein
TKV_c21220	ENOG4105GEU	Spore germination protein
TKV_c21230	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
TKV_c21240	ENOG4105FH5	Membrane
TKV_c21250	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
TKV_c21270	ENOG4107QX3	carboxylase
TKV_c21280	ENOG4105D5P	Methylmalonyl-coA mutase
TKV_c21300	ENOG4105BZU	Histidine kinase
TKV_c21320	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
TKV_c21330	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
TKV_c21370	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TKV_c21380	ENOG4105SX7	Transporter
TKV_c21420	ENOG4108T0W	nitrous oxide maturation protein NosY
TKV_c21460	ENOG4105CPQ	Dehydrogenase
TKV_c21500	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
TKV_c21510	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TKV_c21600	ENOG4105CJ1	ABC, transporter
TKV_c21610	ENOG41082YX	Transcriptional regulator, arsr family
TKV_c21620	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
TKV_c21700	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
TKV_c21850	ENOG4105D49	3-dehydroquinate synthase
TKV_c21860	ENOG41060GV	RNA binding s1 domain protein
TKV_c21910	ENOG4105VYY	sporulation protein yabp
TKV_c21920	ENOG4105JFG	SpoIID LytB domain protein
TKV_c21930	ENOG41082I2	s4 domain protein
TKV_c21940	ENOG4105K70	DNA-binding protein
TKV_c21950	ENOG4108IY2	MazG family
TKV_c21970	ENOG4107SFI	Major Facilitator superfamily
TKV_c21980	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
TKV_c21990	ENOG4108IJ0	Aspartate ammonia-lyase
TKV_c22000	ENOG4105BZU	Histidine kinase
TKV_c22010	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TKV_c22020	ENOG4105MAX	Superoxide reductase
TKV_c22080	ENOG4108K9K	Uncharacterised protein family (UPF0236)
TKV_c22170	ENOG4105CH7	arginosuccinase
TKV_c22200	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
TKV_c22210	ENOG4105C8Y	Acetylornithine aminotransferase
TKV_c22220	ENOG4105CAS	nag kinase
TKV_c22230	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
TKV_c22240	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
TKV_c22270	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
TKV_c22280	ENOG4105BZ8	glutamate synthase
TKV_c22290	ENOG4105DCG	PHP domain protein
TKV_c22310	ENOG4105DA5	(ABC) transporter
TKV_c22320	ENOG41069JR	
TKV_c22350	ENOG4105EMN	RNA polymerase sigma factor
TKV_c22590	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
TKV_c22600	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
TKV_c22610	ENOG4105N67	Proton-coupled thiamine transporter YuaJ
TKV_c22620	ENOG4105BZ1	(ABC) transporter
TKV_c22640	ENOG41067TZ	transcriptional regulator, MarR family
TKV_c22690	ENOG4105CPC	Aldo Keto reductase
TKV_c22750	ENOG4105CJ1	ABC, transporter
TKV_c22770	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
TKV_c22780	ENOG4105C75	arginyL-tRNA synthetase
TKV_c22800	ENOG4105CPF	Cell wall formation (By similarity)
TKV_c22810	ENOG4105XEW	small acid-soluble spore protein
TKV_c22820	ENOG4105MSI	germination protein ypeb
TKV_c22840	ENOG4108ZXQ	stage ii sporulation protein r
TKV_c22860	ENOG4108Q8B	Spore germination protein
TKV_c22910	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
TKV_c22930	ENOG4105W42	Veg protein
TKV_c22940	ENOG4108K9K	Uncharacterised protein family (UPF0236)
TKV_c22950	ENOG4105XFA	sporulation peptidase YabG
TKV_c22960	ENOG4108M14	stage v sporulation protein t
TKV_c22970	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
TKV_c22980	ENOG4108JA2	transcriptioN-repair coupling factor
TKV_c23010	ENOG4105C0H	protease
TKV_c23020	ENOG4105BZU	Histidine kinase
TKV_c23030	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TKV_c23040	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
TKV_c23050	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
TKV_c23070	ENOG4105DFT	pur operon repressor
TKV_c23080	ENOG4105DFU	Cell wall formation (By similarity)
TKV_c23090	ENOG4105ETE	Transcriptional regulator (LacI family
TKV_c23110	ENOG4105VN1	Heat shock protein
TKV_c23130	ENOG4105DM4	PTS System
TKV_c23140	ENOG4105DM4	PTS System
TKV_c23150	ENOG4105DE4	1-phosphofructokinase
TKV_c23160	ENOG4105E98	transcriptional regulator DeoR family
TKV_c23200	ENOG4105RYY	domain protein
TKV_c23240	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
TKV_c23310	ENOG4108CDS	Sucrose-6F-phosphate phosphohydrolase
TKV_c23350	ENOG4105C5R	Aminotransferase
TKV_c23380	ENOG4105CN1	protease
TKV_c23390	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
TKV_c23400	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
TKV_c23420	ENOG41090I5	UPF0735 ACT domain-containing protein
TKV_c23430	ENOG4105CUB	amino acid
TKV_c23440	ENOG4105Q2H	domain protein
TKV_c23460	ENOG4105CKB	glycosidase
TKV_c23490	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
TKV_c23590	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
TKV_c23600	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
TKV_c23780	ENOG4107YH3	SUF system FeS assembly protein, NifU family
TKV_c23810	ENOG4105DIW	FeS assembly protein SUFB
TKV_c23820	ENOG4105C3K	feS assembly ATPase SufC
TKV_c23830	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
TKV_c23870	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
TKV_c23920	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
TKV_c23960	ENOG4105BZU	Histidine kinase
TKV_c23990	ENOG4105DR5	peptidase
TKV_c24050	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
TKV_c24090	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
TKV_c24110	ENOG4105CBC	glutamate synthase
TKV_c24120	ENOG4105EYU	Glutamine amido-transferase
TKV_c24140	ENOG4108YZA	Nitrogen regulatory protein pii
TKV_c24150	ENOG4105BZU	Histidine kinase
TKV_c24170	ENOG4105BZU	Histidine kinase
TKV_c24210	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
TKV_c24220	ENOG4105DZ0	fad dependent oxidoreductase
TKV_c24230	ENOG4105C8Q	Methyl-accepting chemotaxis
TKV_c24250	ENOG4108JYZ	YitT family
TKV_c24280	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
TKV_c24290	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
TKV_c24450	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
TKV_c24520	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
TKV_c24530	ENOG4105IJJ	transcriptional regulator, crp fnr family
TKV_c24540	ENOG4105CDU	Replicative dna helicase
TKV_c24550	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
TKV_c24560	ENOG4105BZR	domain protein
TKV_c24590	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
TKV_c24600	ENOG4108UUM	single-stranded DNA-binding protein
TKV_c24610	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
TKV_c24620	ENOG4105VDK	protein, conserved in bacteria
TKV_c24630	ENOG4105D8X	mechanosensitive ion channel
TKV_c24640	ENOG4108ZDA	Sporulation protein YyaC
TKV_c24690	ENOG4105C9B	Cysteine desulfurase
TKV_c24700	ENOG4105FA0	parb-like partition protein
TKV_c24710	ENOG4107QJE	Chromosome Partitioning Protein
TKV_c24720	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
TKV_c24760	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
TKV_c24770	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
TKV_c24780	ENOG4107R4E	Membrane
TKV_c24790	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
TKV_c24800	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
TKV_c24810	ENOG4105VG0	50S ribosomal protein l34