locus-tag	class	description
Teth39_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Teth39_0002	COG0592	DNA-directed DNA polymerase activity
Teth39_0003	COG2501	S4 domain
Teth39_0004	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Teth39_0007	COG3442	glutamine amidotransferase
Teth39_0009	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Teth39_0010	COG0187	DNA topoisomerase II activity
Teth39_0011	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Teth39_0012	COG1902	pentaerythritol trinitrate reductase activity
Teth39_0013	COG0440	acetolactate synthase activity
Teth39_0014	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Teth39_0015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Teth39_0016	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Teth39_0017	COG0066	3-isopropylmalate dehydratase activity
Teth39_0018	COG0473	3-isopropylmalate dehydrogenase activity
Teth39_0019	COG0129	dihydroxy-acid dehydratase activity
Teth39_0020	COG0028	Belongs to the TPP enzyme family
Teth39_0023	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Teth39_0023	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Teth39_0024	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Teth39_0025	COG0628	permease
Teth39_0029	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Teth39_0030	COG0582	viral genome integration into host DNA
Teth39_0032	COG1396	sequence-specific DNA binding
Teth39_0041	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Teth39_0041	COG2199	diguanylate cyclase activity
Teth39_0049	COG3344	reverse transcriptase
Teth39_0061	COG0739	heme binding
Teth39_0065	COG4962	Type ii secretion system protein e
Teth39_0075	COG3409	Peptidoglycan-binding domain 1 protein
Teth39_0075	COG3773	Cell wall hydrolase
Teth39_0088	COG0358	DNA primase activity
Teth39_0093	COG0582	viral genome integration into host DNA
Teth39_0095	COG2333	competence protein COMEC
Teth39_0095	COG0658	competence protein
Teth39_0097	COG3344	reverse transcriptase
Teth39_0098	COG0308	aminopeptidase N
Teth39_0099	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Teth39_0101	COG0739	heme binding
Teth39_0103	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Teth39_0104	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Teth39_0106	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Teth39_0108	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Teth39_0111	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Teth39_0115	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Teth39_0116	COG0396	ATPase activity
Teth39_0117	COG0719	Fe-S assembly protein
Teth39_0119	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Teth39_0120	COG0822	iron-sulfur transferase activity
Teth39_0132	COG3340	Belongs to the peptidase S51 family
Teth39_0134	COG1518	maintenance of DNA repeat elements
Teth39_0135	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
Teth39_0137	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Teth39_0138	COG3344	reverse transcriptase
Teth39_0139	COG4492	Belongs to the UPF0735 family
Teth39_0140	COG0460	homoserine dehydrogenase
Teth39_0141	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Teth39_0142	COG0083	homoserine kinase activity
Teth39_0144	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Teth39_0145	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Teth39_0147	COG0504	CTP synthase activity
Teth39_0149	COG3344	reverse transcriptase
Teth39_0150	COG1349	DNA-binding transcription factor activity
Teth39_0152	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Teth39_0152	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Teth39_0152	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Teth39_0155	COG0071	Belongs to the small heat shock protein (HSP20) family
Teth39_0158	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Teth39_0159	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Teth39_0160	COG2088	sporulation resulting in formation of a cellular spore
Teth39_0161	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Teth39_0162	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Teth39_0163	COG3344	reverse transcriptase
Teth39_0164	COG0745	RESPONSE REGULATOR receiver
Teth39_0165	COG5002	protein histidine kinase activity
Teth39_0166	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Teth39_0167	COG0193	aminoacyl-tRNA hydrolase activity
Teth39_0169	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Teth39_0170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Teth39_0171	COG2002	toxin-antitoxin pair type II binding
Teth39_0174	COG4466	Protein conserved in bacteria
Teth39_0175	COG1388	LysM domain
Teth39_0176	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Teth39_0177	COG1802	Transcriptional regulator
Teth39_0180	COG0697	spore germination
Teth39_0181	COG0531	amino acid
Teth39_0184	COG3409	Peptidoglycan-binding domain 1 protein
Teth39_0184	COG3773	Cell wall hydrolase
Teth39_0185	COG2959	enzyme of heme biosynthesis
Teth39_0187	COG1181	Belongs to the D-alanine--D-alanine ligase family
Teth39_0189	COG0018	arginyl-trna synthetase
Teth39_0190	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Teth39_0191	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Teth39_0193	COG1131	(ABC) transporter
Teth39_0198	COG4608	Belongs to the ABC transporter superfamily
Teth39_0199	COG0444	Belongs to the ABC transporter superfamily
Teth39_0201	COG0601	transmembrane transport
Teth39_0202	COG0747	negative chemotaxis
Teth39_0204	COG0667	Aldo Keto reductase
Teth39_0206	COG1012	belongs to the aldehyde dehydrogenase family
Teth39_0206	COG1454	alcohol dehydrogenase
Teth39_0209	COG1846	Transcriptional regulator
Teth39_0211	COG1132	(ABC) transporter
Teth39_0212	COG3859	Proton-coupled thiamine transporter YuaJ
Teth39_0213	COG0671	phosphoesterase, PA-phosphatase related
Teth39_0215	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Teth39_0215	COG1796	DNA polymerase
Teth39_0216	COG0493	'glutamate synthase
Teth39_0216	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Teth39_0223	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Teth39_0224	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Teth39_0225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Teth39_0226	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Teth39_0227	COG0505	Belongs to the CarA family
Teth39_0228	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Teth39_0229	COG0137	argininosuccinate synthase activity
Teth39_0230	COG0165	Argininosuccinate lyase
Teth39_0231	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Teth39_0233	COG0588	phosphoglycerate mutase activity
Teth39_0234	COG1528	Iron-storage protein
Teth39_0242	COG2033	superoxide reductase activity
Teth39_0244	COG1027	Aspartate ammonia-lyase
Teth39_0245	COG1160	GTP binding
Teth39_0246	COG2814	Major facilitator Superfamily
Teth39_0248	COG3956	TIGRFAM MazG family protein
Teth39_0249	COG0776	regulation of translation
Teth39_0250	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Teth39_0251	COG2385	sporulation resulting in formation of a cellular spore
Teth39_0258	COG1098	S1 RNA binding domain
Teth39_0259	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Teth39_0259	COG0248	Ppx GppA phosphatase
Teth39_0260	COG1940	carbohydrate kinase activity
Teth39_0261	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Teth39_0262	COG1175	transmembrane transport
Teth39_0263	COG0395	ABC-type sugar transport system, permease component
Teth39_0265	COG3387	PFAM Glycoside hydrolase 15-related
Teth39_0268	COG2801	Transposase and inactivated derivatives
Teth39_0269	COG3328	transposase activity
Teth39_0270	COG3464	Transposase
Teth39_0271	COG3464	Transposase
Teth39_0274	COG0745	RESPONSE REGULATOR receiver
Teth39_0275	COG2205	protein histidine kinase activity
Teth39_0278	COG2217	Heavy metal translocating P-type atpase
Teth39_0279	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Teth39_0281	COG0482	sulfurtransferase activity
Teth39_0282	COG2217	Heavy metal translocating P-type atpase
Teth39_0283	COG5001	Diguanylate cyclase
Teth39_0283	COG3300	MHYT domain
Teth39_0287	COG0156	8-amino-7-oxononanoate synthase activity
Teth39_0288	COG1063	alcohol dehydrogenase
Teth39_0293	COG1131	(ABC) transporter
Teth39_0296	COG0697	spore germination
Teth39_0298	COG2208	phosphoserine phosphatase activity
Teth39_0299	COG0037	tRNA processing
Teth39_0302	COG3852	Histidine kinase
Teth39_0303	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Teth39_0305	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Teth39_0307	COG5016	pyruvate
Teth39_0307	COG0511	ligase activity, forming carbon-carbon bonds
Teth39_0308	COG4684	Psort location CytoplasmicMembrane, score
Teth39_0309	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Teth39_0310	COG0531	amino acid
Teth39_0311	COG0697	spore germination
Teth39_0316	COG5322	oxidoreductase activity
Teth39_0316	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Teth39_0317	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Teth39_0318	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Teth39_0319	COG0302	gtp cyclohydrolase
Teth39_0320	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Teth39_0321	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Teth39_0322	COG0720	synthase
Teth39_0323	COG1489	DNA binding
Teth39_0324	COG0823	Involved in the tonB-independent uptake of proteins
Teth39_0324	COG1506	peptidase
Teth39_0324	COG4946	Tricorn protease homolog
Teth39_0326	COG4224	UPF0291 protein
Teth39_0330	COG0745	RESPONSE REGULATOR receiver
Teth39_0330	COG3706	GGDEF domain
Teth39_0331	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Teth39_0331	COG3711	transcriptional antiterminator
Teth39_0332	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Teth39_0332	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Teth39_0332	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Teth39_0333	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Teth39_0333	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Teth39_0333	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Teth39_0334	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Teth39_0335	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Teth39_0336	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Teth39_0337	COG0281	malic enzyme
Teth39_0340	COG3880	PFAM UvrB UvrC protein
Teth39_0341	COG3869	Catalyzes the specific phosphorylation of arginine residues in
Teth39_0342	COG0542	response to heat
Teth39_0343	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Teth39_0345	COG4956	integral membrane protein (PIN domain superfamily)
Teth39_0346	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Teth39_0348	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Teth39_0349	COG0442	prolyl-tRNA aminoacylation
Teth39_0351	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Teth39_0352	COG1045	serine acetyltransferase
Teth39_0353	COG0215	cysteine-tRNA ligase activity
Teth39_0355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Teth39_0356	COG3688	RNA-binding protein containing a PIN domain
Teth39_0357	COG1595	DNA-templated transcription, initiation
Teth39_0358	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Teth39_0359	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Teth39_0360	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Teth39_0361	COG0250	Participates in transcription elongation, termination and antitermination
Teth39_0362	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Teth39_0363	COG0081	regulation of translation
Teth39_0364	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Teth39_0365	COG0222	ribosome binding
Teth39_0366	COG0085	RNA polymerase activity
Teth39_0367	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Teth39_0368	COG1358	cellular component organization or biogenesis
Teth39_0369	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Teth39_0370	COG0049	tRNA binding
Teth39_0371	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Teth39_0372	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Teth39_0373	COG0051	transcription antitermination factor activity, RNA binding
Teth39_0374	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Teth39_0375	COG0088	Forms part of the polypeptide exit tunnel
Teth39_0376	COG0089	rRNA binding
Teth39_0377	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Teth39_0378	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Teth39_0379	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Teth39_0380	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Teth39_0381	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Teth39_0382	COG0255	Belongs to the universal ribosomal protein uL29 family
Teth39_0383	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Teth39_0384	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Teth39_0385	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Teth39_0386	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Teth39_0387	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Teth39_0388	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Teth39_0389	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Teth39_0390	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Teth39_0391	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Teth39_0392	COG0200	Binds to the 23S rRNA
Teth39_0393	COG0201	protein transport
Teth39_0394	COG0563	adenylate kinase activity
Teth39_0397	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Teth39_0399	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Teth39_0400	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Teth39_0401	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Teth39_0402	COG0202	RNA polymerase activity
Teth39_0403	COG0203	ribosomal protein L17
Teth39_0404	COG1122	ATPase activity
Teth39_0405	COG1122	ATPase activity
Teth39_0406	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Teth39_0407	COG0101	tRNA pseudouridine synthase activity
Teth39_0408	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Teth39_0409	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Teth39_0412	COG4555	ABC transporter
Teth39_0421	COG3328	transposase activity
Teth39_0425	COG3328	transposase activity
Teth39_0426	COG2801	Transposase and inactivated derivatives
Teth39_0429	COG2033	superoxide reductase activity
Teth39_0431	COG1966	Carbon starvation protein
Teth39_0432	COG1115	amino acid carrier protein
Teth39_0434	COG1320	monovalent cation:proton antiporter activity
Teth39_0438	COG0651	ATP synthesis coupled electron transport
Teth39_0439	COG0651	ATP synthesis coupled electron transport
Teth39_0441	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
Teth39_0446	COG1388	LysM domain
Teth39_0446	COG1705	Flagellar rod assembly protein muramidase FlgJ
Teth39_0448	COG0546	phosphoglycolate phosphatase activity
Teth39_0451	COG0714	Associated with various cellular activities
Teth39_0457	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Teth39_0459	COG3426	butyrate kinase activity
Teth39_0460	COG0280	phosphate acetyltransferase
Teth39_0461	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Teth39_0462	COG3426	butyrate kinase activity
Teth39_0468	COG0280	phosphate acetyltransferase
Teth39_0470	COG0204	Acyl-transferase
Teth39_0470	COG0318	PFAM AMP-dependent synthetase and ligase
Teth39_0471	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Teth39_0472	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Teth39_0474	COG0432	Pfam Uncharacterised protein family UPF0047
Teth39_0475	COG1793	dna ligase
Teth39_0476	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
Teth39_0480	COG1151	hydroxylamine reductase activity
Teth39_0484	COG0736	holo-[acyl-carrier-protein] synthase activity
Teth39_0485	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Teth39_0485	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Teth39_0487	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Teth39_0489	COG2337	Toxic component of a toxin-antitoxin (TA) module
Teth39_0490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Teth39_0491	COG3959	Transketolase, thiamine diphosphate binding domain
Teth39_0492	COG3958	Transketolase
Teth39_0494	COG0205	6-phosphofructokinase activity
Teth39_0495	COG1757	Na H antiporter
Teth39_0496	COG2205	protein histidine kinase activity
Teth39_0497	COG1773	rubredoxin
Teth39_0498	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Teth39_0500	COG0460	homoserine dehydrogenase
Teth39_0502	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Teth39_0503	COG0673	inositol 2-dehydrogenase activity
Teth39_0504	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
Teth39_0504	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Teth39_0505	COG3459	Glycosyltransferase 36 associated
Teth39_0506	COG1131	(ABC) transporter
Teth39_0514	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Teth39_0515	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Teth39_0516	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Teth39_0517	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Teth39_0518	COG0131	Imidazoleglycerol-phosphate dehydratase
Teth39_0519	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Teth39_0522	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Teth39_0522	COG0140	phosphoribosyl-ATP diphosphatase activity
Teth39_0523	COG3344	reverse transcriptase
Teth39_0524	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Teth39_0526	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Teth39_0527	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Teth39_0529	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Teth39_0534	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
Teth39_0535	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Teth39_0536	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Teth39_0538	COG0446	pyridine nucleotide-disulphide oxidoreductase
Teth39_0541	COG2204	response regulator
Teth39_0542	COG2376	Dihydroxyacetone kinase
Teth39_0544	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Teth39_0544	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
Teth39_0544	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Teth39_0545	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Teth39_0553	COG0849	cell division
Teth39_0557	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Teth39_0558	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Teth39_0559	COG0019	diaminopimelate decarboxylase activity
Teth39_0561	COG3842	ATPase activity
Teth39_0562	COG3835	regulator
Teth39_0563	COG2884	Cell division ATP-binding protein ftsE
Teth39_0564	COG2177	Part of the ABC transporter FtsEX involved in
Teth39_0565	COG0739	heme binding
Teth39_0566	COG0793	Belongs to the peptidase S41A family
Teth39_0566	COG3409	Peptidoglycan-binding domain 1 protein
Teth39_0567	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Teth39_0568	COG2045	Belongs to the ComB family
Teth39_0569	COG0556	nucleotide-excision repair
Teth39_0571	COG1716	ATPase activity
Teth39_0573	COG0768	penicillin binding
Teth39_0574	COG0322	excinuclease ABC activity
Teth39_0576	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
Teth39_0578	COG1940	carbohydrate kinase activity
Teth39_0579	COG0318	PFAM AMP-dependent synthetase and ligase
Teth39_0581	COG3885	ferrous iron binding
Teth39_0581	COG2078	PFAM AMMECR1 domain protein
Teth39_0589	COG0673	inositol 2-dehydrogenase activity
Teth39_0590	COG0673	inositol 2-dehydrogenase activity
Teth39_0595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Teth39_0596	COG1349	DNA-binding transcription factor activity
Teth39_0597	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Teth39_0598	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Teth39_0602	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
Teth39_0603	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Teth39_0604	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Teth39_0605	COG1940	carbohydrate kinase activity
Teth39_0611	COG3250	beta-galactosidase activity
Teth39_0612	COG0383	alpha-mannosidase activity
Teth39_0613	COG1653	transport
Teth39_0614	COG1175	transmembrane transport
Teth39_0615	COG0395	ABC-type sugar transport system, permease component
Teth39_0617	COG1917	Cupin 2, conserved barrel domain protein
Teth39_0617	COG4977	sequence-specific DNA binding
Teth39_0619	COG0733	neurotransmitter:sodium symporter activity
Teth39_0623	COG0768	penicillin binding
Teth39_0625	COG2182	Extracellular solute-binding protein
Teth39_0628	COG1621	beta-fructofuranosidase activity
Teth39_0632	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Teth39_0633	COG1609	Transcriptional regulator
Teth39_0637	COG2226	methyltransferase
Teth39_0640	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
Teth39_0641	COG0489	protein tyrosine kinase activity
Teth39_0644	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Teth39_0645	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Teth39_0646	COG0446	pyridine nucleotide-disulphide oxidoreductase
Teth39_0648	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Teth39_0649	COG1120	ATPase activity
Teth39_0655	COG1342	Belongs to the UPF0251 family
Teth39_0659	COG3464	Transposase
Teth39_0662	COG1752	Esterase of the alpha-beta hydrolase superfamily
Teth39_0664	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Teth39_0669	COG2182	Extracellular solute-binding protein
Teth39_0670	COG1175	transmembrane transport
Teth39_0671	COG3833	ABC-type maltose transport systems, permease component
Teth39_0675	COG1426	Protein conserved in bacteria
Teth39_0676	COG0366	Alpha amylase catalytic
Teth39_0678	COG1481	regulation of sporulation
Teth39_0679	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Teth39_0680	COG4109	DRTGG domain
Teth39_0683	COG0205	6-phosphofructokinase activity
Teth39_0686	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Teth39_0688	COG0534	Mate efflux family protein
Teth39_0689	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Teth39_0692	COG2195	Cleaves the N-terminal amino acid of tripeptides
Teth39_0693	COG0778	Nitroreductase
Teth39_0694	COG0166	Belongs to the GPI family
Teth39_0695	COG0058	SHG alpha-glucan phosphorylase activity
Teth39_0696	COG0646	methionine synthase
Teth39_0696	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Teth39_0697	COG0646	methionine synthase
Teth39_0697	COG1410	methionine synthase
Teth39_0698	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Teth39_0699	COG3546	catalase activity
Teth39_0702	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Teth39_0707	COG0463	Glycosyl transferase, family 2
Teth39_0708	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Teth39_0710	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Teth39_0713	COG0564	pseudouridine synthase activity
Teth39_0715	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Teth39_0722	COG1067	ATP-dependent peptidase activity
Teth39_0723	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Teth39_0724	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Teth39_0725	COG2720	vancomycin resistance protein
Teth39_0727	COG0561	phosphatase activity
Teth39_0728	COG1254	Belongs to the acylphosphatase family
Teth39_0729	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Teth39_0730	COG2390	Transcriptional regulator
Teth39_0732	COG0126	phosphoglycerate kinase activity
Teth39_0733	COG0149	triose-phosphate isomerase activity
Teth39_0735	COG0148	phosphopyruvate hydratase activity
Teth39_0736	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Teth39_0737	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Teth39_0738	COG0358	DNA primase activity
Teth39_0739	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Teth39_0740	COG2384	SAM-dependent methyltransferase
Teth39_0741	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Teth39_0743	COG0813	purine-nucleoside phosphorylase activity
Teth39_0744	COG1482	cell wall glycoprotein biosynthetic process
Teth39_0745	COG0475	glutathione-regulated potassium exporter activity
Teth39_0748	COG0701	Predicted permease
Teth39_0750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Teth39_0751	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Teth39_0753	COG1956	GAF domain-containing protein
Teth39_0754	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Teth39_0756	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Teth39_0757	COG1278	Cold shock
Teth39_0758	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Teth39_0759	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Teth39_0760	COG0745	RESPONSE REGULATOR receiver
Teth39_0763	COG4399	Belongs to the UPF0754 family
Teth39_0764	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Teth39_0766	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Teth39_0767	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Teth39_0768	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Teth39_0769	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Teth39_0770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Teth39_0771	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Teth39_0772	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Teth39_0772	COG0072	phenylalanine-tRNA ligase activity
Teth39_0774	COG0826	peptidase U32
Teth39_0775	COG1193	negative regulation of DNA recombination
Teth39_0776	COG1683	Conserved Protein
Teth39_0780	COG2197	response regulator
Teth39_0781	COG1362	aminopeptidase activity
Teth39_0782	COG2340	Cysteine-rich secretory protein family
Teth39_0785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Teth39_0786	COG0321	lipoyl(octanoyl) transferase activity
Teth39_0787	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Teth39_0789	COG0459	protein refolding
Teth39_0790	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Teth39_0791	COG0022	dehydrogenase e1 component
Teth39_0792	COG3199	ATP-NAD kinase
Teth39_0793	COG0508	dehydrogenase complex catalyzes the overall conversion of
Teth39_0798	COG0301	tRNA thio-modification
Teth39_0800	COG0012	GTP binding
Teth39_0802	COG0612	Peptidase, M16
Teth39_0803	COG0612	Peptidase, M16
Teth39_0804	COG2001	Belongs to the MraZ family
Teth39_0805	COG0275	rRNA processing
Teth39_0806	COG3116	cell division
Teth39_0807	COG0768	penicillin binding
Teth39_0808	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Teth39_0809	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Teth39_0810	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Teth39_0811	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Teth39_0812	COG0772	Belongs to the SEDS family
Teth39_0813	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Teth39_0814	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Teth39_0817	COG3856	small basic protein
Teth39_0818	COG0849	cell division
Teth39_0819	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Teth39_0821	COG1191	sigma factor activity
Teth39_0822	COG1191	sigma factor activity
Teth39_0823	COG1873	PFAM PRC-barrel domain
Teth39_0824	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Teth39_0825	COG0745	RESPONSE REGULATOR receiver
Teth39_0826	COG5002	protein histidine kinase activity
Teth39_0827	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Teth39_0828	COG0573	inorganic phosphate transmembrane transporter activity
Teth39_0829	COG0581	inorganic phosphate transmembrane transporter activity
Teth39_0830	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Teth39_0831	COG0704	Plays a role in the regulation of phosphate uptake
Teth39_0839	COG1160	GTP binding
Teth39_0840	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Teth39_0841	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Teth39_0846	COG3835	regulator
Teth39_0849	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Teth39_0850	COG2414	aldehyde ferredoxin oxidoreductase
Teth39_0853	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Teth39_0858	COG0521	Mo-molybdopterin cofactor biosynthetic process
Teth39_0859	COG0303	'Molybdopterin
Teth39_0860	COG1910	domain protein
Teth39_0862	COG0315	cyclic pyranopterin monophosphate synthase activity
Teth39_0865	COG4948	Mandelate Racemase Muconate Lactonizing
Teth39_0868	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Teth39_0869	COG1799	cell septum assembly
Teth39_0871	COG2302	S4 RNA-binding domain
Teth39_0872	COG3599	regulation of cell shape
Teth39_0874	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Teth39_0875	COG0402	S-adenosylhomocysteine deaminase activity
Teth39_0876	COG0235	Class ii aldolase
Teth39_0877	COG2188	Transcriptional regulator
Teth39_0879	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Teth39_0880	COG1122	ATPase activity
Teth39_0882	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Teth39_0887	COG3344	reverse transcriptase
Teth39_0889	COG0512	Glutamine amidotransferase of anthranilate synthase
Teth39_0889	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Teth39_0890	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Teth39_0891	COG0134	indole-3-glycerol-phosphate synthase activity
Teth39_0892	COG0135	phosphoribosylanthranilate isomerase activity
Teth39_0893	COG0133	tryptophan synthase activity
Teth39_0894	COG0159	tryptophan synthase activity
Teth39_0895	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Teth39_0896	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Teth39_0897	COG0626	cystathionine gamma-synthase activity
Teth39_0904	COG1703	isobutyryl-CoA mutase activity
Teth39_0905	COG0346	lactoylglutathione lyase activity
Teth39_0907	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
Teth39_0910	COG1595	DNA-templated transcription, initiation
Teth39_0911	COG0778	Nitroreductase
Teth39_0913	COG1970	mechanosensitive ion channel activity
Teth39_0928	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Teth39_0936	COG1132	(ABC) transporter
Teth39_0946	COG1132	(ABC) transporter
Teth39_0951	COG1132	(ABC) transporter
Teth39_0955	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
Teth39_0958	COG0693	protein deglycase activity
Teth39_0960	COG2267	carboxylic ester hydrolase activity
Teth39_0961	COG3344	reverse transcriptase
Teth39_0964	COG0584	glycerophosphoryl diester phosphodiesterase
Teth39_0966	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Teth39_0967	COG1968	undecaprenyl-diphosphatase activity
Teth39_0970	COG3069	C4-dicarboxylate transmembrane transporter activity
Teth39_0972	COG0426	domain, Protein
Teth39_0973	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Teth39_0975	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Teth39_0976	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Teth39_0977	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Teth39_0980	COG1760	l-serine dehydratase
Teth39_0981	COG1164	Oligoendopeptidase f
Teth39_0982	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Teth39_0983	COG1605	Chorismate mutase
Teth39_0983	COG0077	Prephenate dehydratase
Teth39_0984	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Teth39_0985	COG0287	Prephenate dehydrogenase
Teth39_0986	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Teth39_0988	COG3773	Cell wall hydrolase
Teth39_0988	COG3409	Peptidoglycan-binding domain 1 protein
Teth39_0989	COG2119	membrane
Teth39_0992	COG0363	glucosamine-6-phosphate deaminase activity
Teth39_0993	COG0785	Cytochrome C biogenesis protein
Teth39_0994	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Teth39_0995	COG3118	belongs to the thioredoxin family
Teth39_0996	COG1982	Orn Lys Arg decarboxylase major
Teth39_1000	COG2385	sporulation resulting in formation of a cellular spore
Teth39_1001	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Teth39_1004	COG1739	Uncharacterized protein family UPF0029
Teth39_1008	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Teth39_1009	COG0217	transcriptional regulatory protein
Teth39_1010	COG0835	chemotaxis
Teth39_1012	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Teth39_1013	COG0632	four-way junction helicase activity
Teth39_1014	COG2255	four-way junction helicase activity
Teth39_1016	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Teth39_1017	COG0343	queuine tRNA-ribosyltransferase activity
Teth39_1021	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Teth39_1022	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Teth39_1023	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Teth39_1024	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Teth39_1024	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Teth39_1026	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Teth39_1026	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Teth39_1027	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Teth39_1028	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Teth39_1029	COG1490	D-aminoacyl-tRNA deacylase activity
Teth39_1030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Teth39_1031	COG0577	efflux transmembrane transporter activity
Teth39_1032	COG1136	(ABC) transporter
Teth39_1035	COG0124	histidyl-tRNA synthetase
Teth39_1036	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Teth39_1037	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Teth39_1038	COG1937	Protein conserved in bacteria
Teth39_1039	COG3118	belongs to the thioredoxin family
Teth39_1040	COG3804	dihydrodipicolinate reductase
Teth39_1042	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Teth39_1044	COG5012	cobalamin binding
Teth39_1046	COG3457	Alanine racemase
Teth39_1047	COG0346	lactoylglutathione lyase activity
Teth39_1048	COG1959	2 iron, 2 sulfur cluster binding
Teth39_1049	COG0482	sulfurtransferase activity
Teth39_1051	COG0628	permease
Teth39_1052	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Teth39_1053	COG4472	Bacterial protein of unknown function (DUF965)
Teth39_1054	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Teth39_1055	COG3906	Belongs to the UPF0473 family
Teth39_1056	COG0735	belongs to the Fur family
Teth39_1057	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Teth39_1058	COG3679	Belongs to the UPF0342 family
Teth39_1059	COG4708	membrane
Teth39_1060	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Teth39_1063	COG0768	penicillin binding
Teth39_1064	COG1191	sigma factor activity
Teth39_1066	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Teth39_1071	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Teth39_1080	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Teth39_1082	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Teth39_1083	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Teth39_1084	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Teth39_1085	COG0006	proline dipeptidase activity
Teth39_1086	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Teth39_1088	COG3854	ATPases associated with a variety of cellular activities
Teth39_1096	COG1302	Protein conserved in bacteria
Teth39_1097	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Teth39_1098	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Teth39_1099	COG1570	exodeoxyribonuclease VII activity
Teth39_1100	COG1722	exodeoxyribonuclease VII activity
Teth39_1103	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Teth39_1104	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Teth39_1105	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Teth39_1106	COG1438	arginine binding
Teth39_1107	COG0497	DNA recombination
Teth39_1108	COG0750	zinc metalloprotease
Teth39_1116	COG1379	DNA repair
Teth39_1117	COG1300	Membrane
Teth39_1118	COG4974	Belongs to the 'phage' integrase family
Teth39_1119	COG1686	Belongs to the peptidase S11 family
Teth39_1120	COG1366	Belongs to the anti-sigma-factor antagonist family
Teth39_1121	COG2172	sigma factor antagonist activity
Teth39_1123	COG3360	Dodecin
Teth39_1127	COG0617	tRNA 3'-terminal CCA addition
Teth39_1128	COG1994	Peptidase M50
Teth39_1129	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Teth39_1130	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Teth39_1131	COG4086	secreted protein
Teth39_1133	COG3874	Sporulation protein YtfJ
Teth39_1134	COG1301	dicarboxylic acid transport
Teth39_1135	COG1030	water channel activity
Teth39_1136	COG4864	UPF0365 protein
Teth39_1138	COG1686	Belongs to the peptidase S11 family
Teth39_1140	COG0445	tRNA wobble uridine modification
Teth39_1141	COG1187	pseudouridine synthase activity
Teth39_1143	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Teth39_1144	COG0010	Belongs to the arginase family
Teth39_1146	COG1705	Flagellar rod assembly protein muramidase FlgJ
Teth39_1146	COG1388	LysM domain
Teth39_1148	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Teth39_1150	COG0674	pyruvate-flavodoxin oxidoreductase activity
Teth39_1150	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Teth39_1151	COG1013	pyruvate-flavodoxin oxidoreductase activity
Teth39_1155	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Teth39_1156	COG1914	H( )-stimulated, divalent metal cation uptake system
Teth39_1157	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Teth39_1158	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Teth39_1159	COG1984	allophanate hydrolase subunit 2
Teth39_1160	COG4336	lyase activity
Teth39_1163	COG0406	alpha-ribazole phosphatase activity
Teth39_1164	COG2081	HI0933 family
Teth39_1167	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Teth39_1169	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Teth39_1170	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Teth39_1170	COG0539	negative regulation of cytoplasmic translation
Teth39_1171	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Teth39_1172	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Teth39_1173	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Teth39_1174	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Teth39_1175	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Teth39_1176	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Teth39_1177	COG1923	regulation of RNA biosynthetic process
Teth39_1178	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Teth39_1179	COG0328	RNA-DNA hybrid ribonuclease activity
Teth39_1180	COG4974	Belongs to the 'phage' integrase family
Teth39_1181	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
Teth39_1182	COG0464	growth
Teth39_1183	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Teth39_1185	COG0613	PHP domain protein
Teth39_1186	COG2359	stage V sporulation protein S
Teth39_1187	COG1692	metallophosphoesterase
Teth39_1188	COG1418	mRNA catabolic process
Teth39_1190	COG2137	regulation of response to DNA damage stimulus
Teth39_1191	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Teth39_1192	COG1546	Belongs to the CinA family
Teth39_1192	COG1058	Belongs to the CinA family
Teth39_1193	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Teth39_1194	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Teth39_1195	COG1674	ftsk spoiiie
Teth39_1197	COG0740	serine-type endopeptidase activity
Teth39_1198	COG0527	aspartate kinase activity
Teth39_1200	COG0756	dUTP diphosphatase activity
Teth39_1201	COG0612	Peptidase, M16
Teth39_1202	COG0726	polysaccharide deacetylase
Teth39_1203	COG1185	polyribonucleotide nucleotidyltransferase activity
Teth39_1204	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Teth39_1205	COG0196	riboflavin kinase activity
Teth39_1206	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Teth39_1207	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Teth39_1208	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Teth39_1209	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Teth39_1211	COG2740	Nucleic-acid-binding protein implicated in transcription termination
Teth39_1212	COG0195	Participates in both transcription termination and antitermination
Teth39_1213	COG0779	Required for maturation of 30S ribosomal subunits
Teth39_1214	COG2176	DNA-directed DNA polymerase activity
Teth39_1216	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Teth39_1217	COG0750	zinc metalloprotease
Teth39_1218	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Teth39_1219	COG4589	Belongs to the CDS family
Teth39_1220	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Teth39_1222	COG0233	cytoplasmic translational termination
Teth39_1223	COG0528	UMP kinase activity
Teth39_1224	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Teth39_1225	COG0052	Belongs to the universal ribosomal protein uS2 family
Teth39_1228	COG1191	sigma factor activity
Teth39_1229	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Teth39_1230	COG1776	CheC inhibitor of MCP methylation
Teth39_1231	COG0835	chemotaxis
Teth39_1232	COG0643	Histidine kinase
Teth39_1232	COG2198	Histidine kinase
Teth39_1233	COG2201	protein-glutamate methylesterase activity
Teth39_1235	COG0455	bacterial-type flagellum organization
Teth39_1236	COG1419	protein localization to endoplasmic reticulum
Teth39_1237	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Teth39_1238	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Teth39_1239	COG1684	flagellar biosynthetic protein fliR
Teth39_1240	COG1987	bacterial-type flagellum assembly
Teth39_1241	COG1338	Plays a role in the flagellum-specific transport system
Teth39_1243	COG2201	protein-glutamate methylesterase activity
Teth39_1244	COG1776	CheC inhibitor of MCP methylation
Teth39_1244	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Teth39_1245	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Teth39_1247	COG1582	Flagellar protein (FlbD)
Teth39_1250	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Teth39_1254	COG1157	protein secretion by the type III secretion system
Teth39_1256	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Teth39_1257	COG1766	The M ring may be actively involved in energy transduction
Teth39_1258	COG1677	Flagellar hook-basal body complex protein FliE
Teth39_1260	COG1815	bacterial-type flagellum-dependent cell motility
Teth39_1261	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
Teth39_1262	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Teth39_1263	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Teth39_1264	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Teth39_1265	COG0758	DNA mediated transformation
Teth39_1265	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Teth39_1266	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Teth39_1267	COG0792	nuclease activity
Teth39_1268	COG0180	Tryptophanyl-tRNA synthetase
Teth39_1269	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Teth39_1270	COG0606	chelatase, subunit chli
Teth39_1272	COG0335	large ribosomal subunit rRNA binding
Teth39_1273	COG0336	Belongs to the RNA methyltransferase TrmD family
Teth39_1274	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Teth39_1275	COG1837	Belongs to the UPF0109 family
Teth39_1276	COG0228	four-way junction DNA binding
Teth39_1277	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Teth39_1278	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
Teth39_1279	COG0552	protein localization to endoplasmic reticulum
Teth39_1282	COG2359	stage V sporulation protein S
Teth39_1284	COG0571	ribonuclease III activity
Teth39_1285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Teth39_1286	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Teth39_1287	COG1028	Short-chain dehydrogenase reductase Sdr
Teth39_1288	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Teth39_1289	COG2070	2-Nitropropane dioxygenase
Teth39_1290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Teth39_1291	COG0416	fatty acid biosynthetic process
Teth39_1292	COG2030	dehydratase
Teth39_1293	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Teth39_1294	COG1399	metal-binding, possibly nucleic acid-binding protein
Teth39_1295	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Teth39_1296	COG0280	phosphate acetyltransferase
Teth39_1297	COG1323	Belongs to the UPF0348 family
Teth39_1298	COG3314	Sporulation integral membrane protein YlbJ
Teth39_1300	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Teth39_1301	COG0742	ribosomal rna small subunit methyltransferase
Teth39_1304	COG1307	EDD domain protein, DegV family
Teth39_1305	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Teth39_1306	COG1461	Dihydroxyacetone kinase
Teth39_1307	COG1302	Protein conserved in bacteria
Teth39_1308	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Teth39_1311	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Teth39_1312	COG1162	GTPase activity
Teth39_1313	COG0515	serine threonine protein kinase
Teth39_1313	COG2815	serine threonine protein kinase
Teth39_1314	COG0631	protein serine/threonine phosphatase activity
Teth39_1315	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Teth39_1316	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Teth39_1316	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Teth39_1317	COG2738	Putative neutral zinc metallopeptidase
Teth39_1319	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Teth39_1320	COG0242	peptide deformylase activity
Teth39_1321	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Teth39_1322	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Teth39_1323	COG1758	RNA polymerase activity
Teth39_1324	COG0194	GDP metabolic process
Teth39_1325	COG2052	Domain of unknown function (DUF370)
Teth39_1326	COG1561	YicC-like family, N-terminal region
Teth39_1327	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Teth39_1328	COG2814	Major facilitator Superfamily
Teth39_1332	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Teth39_1333	COG2011	ABC-type metal ion transport system permease component
Teth39_1337	COG0037	tRNA processing
Teth39_1340	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Teth39_1341	COG0167	dihydroorotate dehydrogenase activity
Teth39_1342	COG0543	2 iron, 2 sulfur cluster binding
Teth39_1343	COG0284	orotidine-5'-phosphate decarboxylase activity
Teth39_1344	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Teth39_1345	COG0540	Belongs to the ATCase OTCase family
Teth39_1347	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Teth39_1349	COG0564	pseudouridine synthase activity
Teth39_1350	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Teth39_1351	COG3063	Type IV pilus biogenesis stability protein PilW
Teth39_1355	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Teth39_1356	COG0557	exoribonuclease II activity
Teth39_1358	COG0574	Belongs to the PEP-utilizing enzyme family
Teth39_1358	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Teth39_1359	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Teth39_1360	COG0517	IMP dehydrogenase activity
Teth39_1361	COG0423	glycine-tRNA ligase activity
Teth39_1363	COG1381	Involved in DNA repair and RecF pathway recombination
Teth39_1364	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Teth39_1365	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Teth39_1366	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Teth39_1367	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Teth39_1368	COG1480	7TM receptor with intracellular HD hydrolase
Teth39_1369	COG1702	phosphate starvation-inducible protein PhoH
Teth39_1374	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Teth39_1375	COG0537	adenosine 5'-monophosphoramidase activity
Teth39_1376	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Teth39_1377	COG5001	Diguanylate cyclase
Teth39_1377	COG5002	protein histidine kinase activity
Teth39_1377	COG3447	MASE1 domain protein
Teth39_1378	COG0840	transmembrane signaling receptor activity
Teth39_1383	COG2274	protein secretion by the type I secretion system
Teth39_1384	COG0488	(ABC) transporter
Teth39_1391	COG2264	protein methyltransferase activity
Teth39_1392	COG0484	heat shock protein binding
Teth39_1393	COG0443	Heat shock 70 kDa protein
Teth39_1394	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Teth39_1395	COG1420	regulation of RNA biosynthetic process
Teth39_1396	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Teth39_1397	COG0481	GTPase activity
Teth39_1402	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Teth39_1404	COG0268	Binds directly to 16S ribosomal RNA
Teth39_1407	COG1234	tRNA 3'-trailer cleavage
Teth39_1409	COG4720	Psort location CytoplasmicMembrane, score
Teth39_1412	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Teth39_1413	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Teth39_1419	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Teth39_1420	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Teth39_1421	COG1555	photosystem II stabilization
Teth39_1421	COG1596	polysaccharide export
Teth39_1422	COG1686	Belongs to the peptidase S11 family
Teth39_1423	COG0367	asparagine synthase
Teth39_1427	COG0799	negative regulation of ribosome biogenesis
Teth39_1428	COG1713	HD superfamily hydrolase involved in NAD metabolism
Teth39_1429	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Teth39_1430	COG3344	reverse transcriptase
Teth39_1431	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Teth39_1433	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Teth39_1435	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Teth39_1437	COG4708	membrane
Teth39_1438	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Teth39_1439	COG1530	ribonuclease E activity
Teth39_1442	COG0517	IMP dehydrogenase activity
Teth39_1442	COG1994	Peptidase M50
Teth39_1443	COG0739	heme binding
Teth39_1444	COG1803	Methylglyoxal synthase
Teth39_1445	COG0772	Belongs to the SEDS family
Teth39_1446	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Teth39_1447	COG2894	cell division
Teth39_1448	COG0850	regulation of cytokinetic process
Teth39_1449	COG0768	penicillin binding
Teth39_1452	COG1077	Cell shape determining protein MreB Mrl
Teth39_1453	COG2003	Belongs to the UPF0758 family
Teth39_1454	COG0424	maF-like protein
Teth39_1459	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Teth39_1459	COG4191	Histidine kinase
Teth39_1463	COG2878	Part of a membrane complex involved in electron transport
Teth39_1467	COG0741	lytic transglycosylase activity
Teth39_1469	COG1388	LysM domain
Teth39_1469	COG0791	NLP P60 protein
Teth39_1472	COG0741	lytic transglycosylase activity
Teth39_1473	COG0237	dephospho-CoA kinase activity
Teth39_1474	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Teth39_1474	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Teth39_1479	COG4475	Protein of unknown function (DUF436)
Teth39_1488	COG2986	histidine ammonia-lyase
Teth39_1491	COG0739	heme binding
Teth39_1493	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Teth39_1494	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Teth39_1498	COG1132	(ABC) transporter
Teth39_1499	COG1132	(ABC) transporter
Teth39_1501	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Teth39_1502	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Teth39_1503	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Teth39_1504	COG2171	N-acyltransferase activity
Teth39_1505	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
Teth39_1508	COG3773	Cell wall hydrolase
Teth39_1508	COG3409	Peptidoglycan-binding domain 1 protein
Teth39_1514	COG0395	ABC-type sugar transport system, permease component
Teth39_1517	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Teth39_1518	COG0395	ABC-type sugar transport system, permease component
Teth39_1519	COG1175	transmembrane transport
Teth39_1522	COG1609	Transcriptional regulator
Teth39_1523	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Teth39_1528	COG0285	dihydrofolate synthase activity
Teth39_1530	COG0525	valine-tRNA ligase activity
Teth39_1535	COG0745	RESPONSE REGULATOR receiver
Teth39_1536	COG5002	protein histidine kinase activity
Teth39_1539	COG1691	(AIR) carboxylase
Teth39_1540	COG1606	tRNA processing
Teth39_1541	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Teth39_1543	COG0671	phosphoesterase, PA-phosphatase related
Teth39_1546	COG2814	Major facilitator Superfamily
Teth39_1547	COG0105	UTP biosynthetic process
Teth39_1549	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Teth39_1551	COG3949	Membrane
Teth39_1552	COG1316	TRANSCRIPTIONal
Teth39_1554	COG0489	protein tyrosine kinase activity
Teth39_1555	COG3944	biosynthesis protein
Teth39_1556	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Teth39_1558	COG0250	Participates in transcription elongation, termination and antitermination
Teth39_1559	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Teth39_1560	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
Teth39_1570	COG1914	H( )-stimulated, divalent metal cation uptake system
Teth39_1572	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Teth39_1575	COG4989	oxidoreductase activity
Teth39_1576	COG0622	Phosphoesterase
Teth39_1577	COG1704	LemA family
Teth39_1578	COG0501	Belongs to the peptidase M48B family
Teth39_1582	COG2161	toxin-antitoxin pair type II binding
Teth39_1585	COG1401	restriction endodeoxyribonuclease activity
Teth39_1590	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Teth39_1592	COG0789	Transcriptional regulator
Teth39_1597	COG1979	alcohol dehydrogenase
Teth39_1598	COG0667	Aldo Keto reductase
Teth39_1616	COG0622	Phosphoesterase
Teth39_1617	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Teth39_1626	COG1091	dTDP-4-dehydrorhamnose reductase activity
Teth39_1630	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Teth39_1630	COG0463	Glycosyl transferase, family 2
Teth39_1641	COG2239	Acts as a magnesium transporter
Teth39_1643	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Teth39_1644	COG1116	anion transmembrane transporter activity
Teth39_1645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Teth39_1646	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Teth39_1646	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Teth39_1648	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Teth39_1649	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Teth39_1650	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Teth39_1651	COG0740	serine-type endopeptidase activity
Teth39_1652	COG0544	peptidyl-prolyl cis-trans isomerase activity
Teth39_1654	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
Teth39_1655	COG0352	thiamine-phosphate diphosphorylase activity
Teth39_1656	COG0351	phosphomethylpyrimidine kinase
Teth39_1659	COG0437	4 iron, 4 sulfur cluster binding
Teth39_1660	COG0069	glutamate synthase activity
Teth39_1660	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Teth39_1661	COG0067	glutamate synthase
Teth39_1662	COG0505	Belongs to the CarA family
Teth39_1664	COG0347	Belongs to the P(II) protein family
Teth39_1665	COG0004	ammonium transporteR
Teth39_1667	COG3464	Transposase
Teth39_1669	COG3328	transposase activity
Teth39_1674	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Teth39_1677	COG2721	sulfolactate sulfo-lyase activity
Teth39_1682	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Teth39_1683	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Teth39_1685	COG4608	Belongs to the ABC transporter superfamily
Teth39_1686	COG0444	Belongs to the ABC transporter superfamily
Teth39_1687	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Teth39_1688	COG0601	transmembrane transport
Teth39_1689	COG4166	transmembrane transport
Teth39_1690	COG3464	Transposase
Teth39_1691	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Teth39_1692	COG0154	amidase activity
Teth39_1693	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Teth39_1694	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Teth39_1695	COG0210	DNA helicase
Teth39_1696	COG4496	protein, YerC YecD
Teth39_1697	COG1447	Phosphotransferase system cellobiose-specific component IIA
Teth39_1698	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Teth39_1699	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Teth39_1702	COG3711	transcriptional antiterminator
Teth39_1704	COG2244	polysaccharide biosynthetic process
Teth39_1705	COG1473	amidohydrolase
Teth39_1706	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Teth39_1708	COG0151	Belongs to the GarS family
Teth39_1709	COG0138	bifunctional purine biosynthesis protein purh
Teth39_1710	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Teth39_1711	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Teth39_1712	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Teth39_1713	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Teth39_1714	COG0047	phosphoribosylformylglycinamidine synthase activity
Teth39_1715	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Teth39_1716	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Teth39_1717	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Teth39_1718	COG2252	PERMEase
Teth39_1719	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Teth39_1719	COG0519	Catalyzes the synthesis of GMP from XMP
Teth39_1720	COG0517	IMP dehydrogenase activity
Teth39_1720	COG0516	GMP reductase activity
Teth39_1721	COG0459	protein refolding
Teth39_1722	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Teth39_1725	COG1404	Belongs to the peptidase S8 family
Teth39_1727	COG1811	Na channel or pump
Teth39_1730	COG0493	'glutamate synthase
Teth39_1734	COG3290	protein histidine kinase activity
Teth39_1735	COG3279	Response regulator of the LytR AlgR family
Teth39_1737	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Teth39_1740	COG0488	(ABC) transporter
Teth39_1742	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Teth39_1744	COG1214	PFAM Peptidase M22, glycoprotease
Teth39_1745	COG0802	atpase or kinase
Teth39_1747	COG0549	Belongs to the carbamate kinase family
Teth39_1748	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Teth39_1749	COG2235	arginine
Teth39_1751	COG0398	Pfam SNARE associated Golgi protein
Teth39_1753	COG2183	response to ionizing radiation
Teth39_1754	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Teth39_1755	COG0653	protein targeting
Teth39_1758	COG1827	regulation of RNA biosynthetic process
Teth39_1764	COG0765	amino acid transport
Teth39_1765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Teth39_1766	COG3344	reverse transcriptase
Teth39_1768	COG0840	transmembrane signaling receptor activity
Teth39_1770	COG1516	flagellar protein fliS
Teth39_1771	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Teth39_1774	COG0367	asparagine synthase
Teth39_1780	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Teth39_1781	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
Teth39_1783	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Teth39_1784	COG1256	bacterial-type flagellum assembly
Teth39_1784	COG4786	Flagellar basal body rod
Teth39_1788	COG1040	competence protein
Teth39_1789	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Teth39_1790	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Teth39_1791	COG1592	Rubrerythrin
Teth39_1795	COG5002	protein histidine kinase activity
Teth39_1796	COG0745	RESPONSE REGULATOR receiver
Teth39_1797	COG1609	Transcriptional regulator
Teth39_1798	COG0561	phosphatase activity
Teth39_1799	COG2323	membrane
Teth39_1802	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Teth39_1803	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Teth39_1806	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Teth39_1808	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Teth39_1809	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Teth39_1810	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Teth39_1811	COG2081	HI0933 family
Teth39_1820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Teth39_1821	COG3711	transcriptional antiterminator
Teth39_1822	COG2190	(PTS) system
Teth39_1823	COG2190	(PTS) system
Teth39_1823	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Teth39_1823	COG1263	PTS System
Teth39_1825	COG0840	transmembrane signaling receptor activity
Teth39_1827	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
Teth39_1829	COG2188	Transcriptional regulator
Teth39_1833	COG1744	ABC transporter substrate-binding protein PnrA-like
Teth39_1834	COG3404	Formiminotransferase-cyclodeaminase
Teth39_1835	COG1228	amidohydrolase
Teth39_1837	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Teth39_1838	COG0840	transmembrane signaling receptor activity
Teth39_1840	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Teth39_1840	COG2199	diguanylate cyclase activity
Teth39_1841	COG0531	amino acid
Teth39_1868	COG3344	reverse transcriptase
Teth39_1874	COG1363	Peptidase, m42
Teth39_1883	COG1122	ATPase activity
Teth39_1886	COG0310	cobalt ion transport
Teth39_1888	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Teth39_1889	COG0113	porphobilinogen synthase activity
Teth39_1894	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Teth39_1896	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Teth39_1900	COG1492	cobalamin metabolic process
Teth39_1901	COG1797	cobyrinic acid a,c-diamide synthase activity
Teth39_1902	COG1120	ATPase activity
Teth39_1903	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Teth39_1904	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Teth39_1907	COG0116	Belongs to the methyltransferase superfamily
Teth39_1910	COG0822	iron-sulfur transferase activity
Teth39_1911	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Teth39_1915	COG2221	Nitrite and sulphite reductase 4Fe-4S
Teth39_1919	COG1704	LemA family
Teth39_1922	COG0714	Associated with various cellular activities
Teth39_1923	COG0735	belongs to the Fur family
Teth39_1924	COG0803	Belongs to the bacterial solute-binding protein 9 family
Teth39_1925	COG1121	(ABC) transporter
Teth39_1926	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Teth39_1928	COG3250	beta-galactosidase activity
Teth39_1930	COG0444	Belongs to the ABC transporter superfamily
Teth39_1931	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Teth39_1932	COG0601	transmembrane transport
Teth39_1933	COG4166	transmembrane transport
Teth39_1936	COG0730	response to heat
Teth39_1937	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Teth39_1938	COG0737	Belongs to the 5'-nucleotidase family
Teth39_1939	COG0246	Mannitol dehydrogenase
Teth39_1941	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Teth39_1941	COG3711	transcriptional antiterminator
Teth39_1942	COG2213	PTS system mannitol-specific
Teth39_1943	COG2723	6-phospho-beta-galactosidase activity
Teth39_1944	COG1486	melibiose metabolic process
Teth39_1945	COG1447	Phosphotransferase system cellobiose-specific component IIA
Teth39_1947	COG3394	polysaccharide catabolic process
Teth39_1949	COG3933	PFAM sigma-54 factor interaction domain-containing protein
Teth39_1949	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Teth39_1952	COG2313	pseudouridylate synthase activity
Teth39_1953	COG1522	sequence-specific DNA binding
Teth39_1953	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Teth39_1955	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Teth39_1956	COG0495	leucyl-tRNA aminoacylation
Teth39_1957	COG0390	transport system, permease component
Teth39_1958	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Teth39_1960	COG1924	4 iron, 4 sulfur cluster binding
Teth39_1964	COG1309	transcriptional regulator
Teth39_1968	COG0640	Transcriptional regulator
Teth39_1970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Teth39_1971	COG0800	Aldolase
Teth39_1972	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Teth39_1974	COG0800	Aldolase
Teth39_1975	COG1414	Transcriptional regulator
Teth39_1979	COG1979	alcohol dehydrogenase
Teth39_1980	COG4821	SIS domain
Teth39_1982	COG3037	sugar-specific permease SgaT UlaA
Teth39_1983	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Teth39_1984	COG0436	Aminotransferase
Teth39_1986	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Teth39_1987	COG0095	Lipoate-protein ligase
Teth39_1988	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Teth39_1989	COG0509	glycine decarboxylation via glycine cleavage system
Teth39_1990	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Teth39_1991	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Teth39_1992	COG1980	fructose-bisphosphate aldolase activity
Teth39_1997	COG0039	L-malate dehydrogenase activity
Teth39_2001	COG0297	glycogen (starch) synthase activity
Teth39_2006	COG0450	alkyl hydroperoxide reductase
Teth39_2008	COG0419	ATPase involved in DNA repair
Teth39_2009	COG0420	3'-5' exonuclease activity
Teth39_2010	COG1074	ATP-dependent DNA helicase activity
Teth39_2011	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
Teth39_2012	COG0179	Fumarylacetoacetate (FAA) hydrolase
Teth39_2013	COG1136	(ABC) transporter
Teth39_2013	COG0577	efflux transmembrane transporter activity
Teth39_2014	COG1136	(ABC) transporter
Teth39_2015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Teth39_2016	COG0534	Mate efflux family protein
Teth39_2017	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Teth39_2019	COG0864	Transcriptional regulator
Teth39_2020	COG0310	cobalt ion transport
Teth39_2021	COG0310	cobalt ion transport
Teth39_2022	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Teth39_2023	COG1122	ATPase activity
Teth39_2024	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Teth39_2024	COG1918	ferrous iron import across plasma membrane
Teth39_2026	COG1522	sequence-specific DNA binding
Teth39_2027	COG0436	Aminotransferase
Teth39_2032	COG3328	transposase activity
Teth39_2033	COG3344	reverse transcriptase
Teth39_2037	COG3344	reverse transcriptase
Teth39_2038	COG1879	ABC-type sugar transport system periplasmic component
Teth39_2039	COG1172	Belongs to the binding-protein-dependent transport system permease family
Teth39_2040	COG1129	ABC transporter
Teth39_2041	COG1869	D-ribose catabolic process
Teth39_2042	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Teth39_2043	COG1609	Transcriptional regulator
Teth39_2056	COG0395	ABC-type sugar transport system, permease component
Teth39_2058	COG1653	transport
Teth39_2059	COG1070	Carbohydrate kinase
Teth39_2060	COG2115	Belongs to the xylose isomerase family
Teth39_2061	COG0569	domain protein
Teth39_2062	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Teth39_2063	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Teth39_2064	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Teth39_2065	COG0800	Aldolase
Teth39_2066	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Teth39_2067	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Teth39_2068	COG3716	PTS system mannose fructose sorbose family IID component
Teth39_2070	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Teth39_2071	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Teth39_2071	COG3933	PFAM sigma-54 factor interaction domain-containing protein
Teth39_2072	COG2814	Major facilitator Superfamily
Teth39_2073	COG0800	Aldolase
Teth39_2074	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Teth39_2075	COG4948	Mandelate Racemase Muconate Lactonizing
Teth39_2082	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Teth39_2082	COG3933	PFAM sigma-54 factor interaction domain-containing protein
Teth39_2089	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Teth39_2093	COG4786	Flagellar basal body rod
Teth39_2095	COG1609	Transcriptional regulator
Teth39_2097	COG2385	sporulation resulting in formation of a cellular spore
Teth39_2099	COG0686	Belongs to the AlaDH PNT family
Teth39_2100	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Teth39_2104	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Teth39_2105	COG0698	ribose 5-phosphate isomerase
Teth39_2106	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Teth39_2107	COG0009	L-threonylcarbamoyladenylate synthase
Teth39_2109	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Teth39_2111	COG3872	metal-dependent enzyme
Teth39_2112	COG1435	thymidine kinase activity
Teth39_2113	COG0254	rRNA binding
Teth39_2114	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Teth39_2116	COG0745	RESPONSE REGULATOR receiver
Teth39_2119	COG1245	4Fe-4S binding domain
Teth39_2119	COG2878	Part of a membrane complex involved in electron transport
Teth39_2120	COG4657	Part of a membrane complex involved in electron transport
Teth39_2121	COG4660	Part of a membrane complex involved in electron transport
Teth39_2122	COG4659	FMN binding
Teth39_2123	COG4658	electron transport chain
Teth39_2124	COG4656	Part of a membrane complex involved in electron transport
Teth39_2125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Teth39_2128	COG2151	metal-sulfur cluster biosynthetic enzyme
Teth39_2128	COG0489	protein tyrosine kinase activity
Teth39_2129	COG1191	sigma factor activity
Teth39_2134	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Teth39_2135	COG3584	3D domain protein
Teth39_2135	COG3583	domain protein
Teth39_2136	COG0084	hydrolase, TatD family'
Teth39_2137	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Teth39_2137	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Teth39_2138	COG0617	tRNA 3'-terminal CCA addition
Teth39_2139	COG0700	Nucleoside recognition
Teth39_2140	COG2715	membrane protein required for spore maturation
Teth39_2141	COG2002	toxin-antitoxin pair type II binding
Teth39_2142	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Teth39_2143	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Teth39_2144	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Teth39_2145	COG2235	arginine
Teth39_2146	COG1774	PSP1 C-terminal conserved region
Teth39_2147	COG0470	DNA polymerase III
Teth39_2149	COG3870	Protein conserved in bacteria
Teth39_2150	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Teth39_2151	COG1982	Orn Lys Arg decarboxylase major
Teth39_2153	COG0519	Catalyzes the synthesis of GMP from XMP
Teth39_2154	COG1940	carbohydrate kinase activity
Teth39_2156	COG2391	methyltransferase activity
Teth39_2158	COG2391	methyltransferase activity
Teth39_2159	COG0583	DNA-binding transcription factor activity
Teth39_2169	COG1573	uracil-dna glycosylase
Teth39_2171	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Teth39_2172	COG0037	tRNA processing
Teth39_2173	COG0366	Alpha amylase catalytic
Teth39_2173	COG3103	Sh3 type 3 domain protein
Teth39_2175	COG1028	Short-chain dehydrogenase reductase Sdr
Teth39_2176	COG1181	Belongs to the D-alanine--D-alanine ligase family
Teth39_2179	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Teth39_2180	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Teth39_2181	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Teth39_2183	COG4608	Belongs to the ABC transporter superfamily
Teth39_2184	COG0444	Belongs to the ABC transporter superfamily
Teth39_2186	COG0601	transmembrane transport
Teth39_2187	COG4166	transmembrane transport
Teth39_2188	COG1609	Transcriptional regulator
Teth39_2189	COG1187	pseudouridine synthase activity
Teth39_2190	COG1028	Short-chain dehydrogenase reductase Sdr
Teth39_2195	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Teth39_2196	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Teth39_2197	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Teth39_2198	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Teth39_2199	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Teth39_2200	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Teth39_2201	COG2199	diguanylate cyclase activity
Teth39_2201	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Teth39_2211	COG3344	reverse transcriptase
Teth39_2214	COG3773	Cell wall hydrolase
Teth39_2214	COG3409	Peptidoglycan-binding domain 1 protein
Teth39_2224	COG4962	Type ii secretion system protein e
Teth39_2229	COG0739	heme binding
Teth39_2244	COG1396	sequence-specific DNA binding
Teth39_2246	COG0582	viral genome integration into host DNA
Teth39_2248	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Teth39_2249	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Teth39_2250	COG0840	transmembrane signaling receptor activity
Teth39_2252	COG0446	pyridine nucleotide-disulphide oxidoreductase
Teth39_2257	COG1394	ATPase activity, coupled to movement of substances
Teth39_2258	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
Teth39_2259	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
Teth39_2260	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
Teth39_2261	COG1527	subunit (C
Teth39_2262	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
Teth39_2263	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Teth39_2264	COG1269	ATP hydrolysis coupled proton transport
Teth39_2268	COG0305	Participates in initiation and elongation during chromosome replication
Teth39_2269	COG0359	binds to the 23S rRNA
Teth39_2270	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
Teth39_2273	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Teth39_2274	COG0629	single-stranded DNA binding
Teth39_2275	COG0360	Binds together with S18 to 16S ribosomal RNA
Teth39_2276	COG4481	Protein conserved in bacteria
Teth39_2277	COG0668	transmembrane transport
Teth39_2280	COG4242	Belongs to the peptidase S51 family
Teth39_2281	COG1597	lipid kinase activity
Teth39_2283	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Teth39_2284	COG1475	DNA binding
Teth39_2285	COG1192	Involved in chromosome partitioning
Teth39_2288	COG0357	Ribosomal RNA small subunit methyltransferase G
Teth39_2289	COG0445	tRNA wobble uridine modification
Teth39_2290	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Teth39_2291	COG1847	R3H domain protein
Teth39_2292	COG0706	membrane insertase activity
Teth39_2293	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Teth39_2294	COG0594	ribonuclease P activity
Teth39_2295	COG0230	Belongs to the bacterial ribosomal protein bL34 family