locus-tag	class	description
Tsac_0001	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Tsac_0002	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Tsac_0003	ENOG4108RAC	Rubrerythrin
Tsac_0007	ENOG4108ZDA	Sporulation protein YyaC
Tsac_0009	ENOG4105BZU	Histidine kinase
Tsac_0010	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Tsac_0011	ENOG4105CE4	GlcNAc 6-P deacetylase
Tsac_0012	ENOG4105ETE	Transcriptional regulator (LacI family
Tsac_0014	ENOG410667J	hydrolase
Tsac_0015	ENOG4108QG2	Membrane
Tsac_0022	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
Tsac_0024	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
Tsac_0026	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Tsac_0028	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Tsac_0029	ENOG4107SDT	Homocitrate synthase
Tsac_0034	ENOG4105C8Q	Methyl-accepting chemotaxis
Tsac_0036	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
Tsac_0038	ENOG4105FDP	GntR family transcriptional regulator
Tsac_0040	ENOG4105UIB	(ABC) transporter
Tsac_0041	ENOG4108JQ9	ABC transporter
Tsac_0042	ENOG4105DIH	basic membrane
Tsac_0043	ENOG410908R	Methenyltetrahydrofolate cyclohydrolase
Tsac_0044	ENOG4105CCS	Glutamate formiminotransferase
Tsac_0053	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Tsac_0058	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
Tsac_0059	ENOG4108YZT	Adenosylcobinamide kinase
Tsac_0060	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Tsac_0065	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Tsac_0066	ENOG4105E0A	ABC, transporter
Tsac_0067	ENOG4105EHG	Permease protein
Tsac_0068	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
Tsac_0073	ENOG4105DNE	Transposase
Tsac_0076	ENOG4105CUB	amino acid
Tsac_0077	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
Tsac_0078	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Tsac_0080	ENOG4108ZB6	transcriptional regulator AsnC family
Tsac_0081	ENOG4105CHM	Aminotransferase
Tsac_0083	ENOG4105CE1	Ferrous iron transport protein b
Tsac_0085	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
Tsac_0086	ENOG4105I3K	Ferric uptake regulator, Fur family
Tsac_0087	ENOG4105DSE	periplasmic solute binding protein
Tsac_0088	ENOG4105FDK	ABC transporter
Tsac_0103	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Tsac_0104	ENOG4105CGH	5'-nucleotidase
Tsac_0108	ENOG4105C5Y	PTS System
Tsac_0109	ENOG4106KNT	transcriptional regulator
Tsac_0110	ENOG4105F8D	glycoside hydrolase family 4
Tsac_0111	ENOG4105VCP	PTS System
Tsac_0114	ENOG4105CK1	PTS System
Tsac_0116	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Tsac_0117	ENOG4105E5D	amino acid
Tsac_0118	ENOG4107GRR	phosphate transport regulator
Tsac_0121	ENOG41089WN	small, acid-soluble spore protein tlp
Tsac_0122	ENOG4105C8T	Leucyl-tRNA synthetase
Tsac_0127	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Tsac_0128	ENOG4105BZU	Histidine kinase
Tsac_0129	ENOG4105C8Q	Methyl-accepting chemotaxis
Tsac_0130	ENOG4105CBS	Chea signal transduction histidine kinase
Tsac_0131	ENOG4105YVF	chew protein
Tsac_0133	ENOG4105CHM	Aminotransferase
Tsac_0134	ENOG4108HWW	ABC transporter
Tsac_0136	ENOG4105DFW	ABC transporter
Tsac_0137	ENOG4105DFW	ABC transporter
Tsac_0138	ENOG4105EQD	regulatoR
Tsac_0139	ENOG4105C2F	Histidine kinase
Tsac_0141	ENOG4105NBU	tryptophan transport protein
Tsac_0143	ENOG4105CHR	reductase
Tsac_0144	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
Tsac_0145	ENOG4105ETE	Transcriptional regulator (LacI family
Tsac_0148	ENOG4105CNT	hydrolase family 2
Tsac_0149	ENOG4105DRS	transport system, permease
Tsac_0153	ENOG4105DEI	Mannitol dehydrogenase
Tsac_0154	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
Tsac_0155	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
Tsac_0156	ENOG4108JQ1	Dehydrogenase
Tsac_0160	ENOG4105UQX	Mate efflux family protein
Tsac_0162	ENOG4105CTX	dehydratase
Tsac_0163	ENOG4107QZW	Altronate oxidoreductase
Tsac_0165	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
Tsac_0166	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
Tsac_0168	ENOG4105F5H	Glycosyl Hydrolase Family 88
Tsac_0169	ENOG4107KJX	Transcriptional regulator
Tsac_0170	ENOG4105D2H	Uronic isomerase
Tsac_0175	ENOG4105BZ8	glutamate synthase
Tsac_0176	ENOG4107T5J	pyridine nucleotide-disulfide oxidoreductase
Tsac_0186	ENOG4105C0D	helicase
Tsac_0189	ENOG4105VTR	Integrase
Tsac_0192	ENOG4107ZTW	SNARE associated Golgi
Tsac_0193	ENOG4107QPH	glycogen) synthase
Tsac_0194	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
Tsac_0201	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
Tsac_0202	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
Tsac_0207	ENOG4105EQD	regulatoR
Tsac_0208	ENOG4105DET	Rhamnulokinase
Tsac_0209	ENOG4105DKG	l-rhamnose isomerase
Tsac_0211	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
Tsac_0213	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
Tsac_0214	ENOG4105KNY	Microcompartments protein
Tsac_0215	ENOG4105KNY	Microcompartments protein
Tsac_0216	ENOG4105KNY	Microcompartments protein
Tsac_0217	ENOG4108X49	Ethanolamine utilization protein EutK
Tsac_0218	ENOG4105CPQ	Dehydrogenase
Tsac_0219	ENOG4108EKI	Dehydrogenase
Tsac_0223	ENOG41084PW	diol glycerol dehydratase reactivating factor large subunit
Tsac_0224	ENOG4108ZFT	Dehydratase small subunit
Tsac_0225	ENOG4105YCI	dehydratase medium subunit
Tsac_0228	ENOG4105E98	transcriptional regulator DeoR family
Tsac_0232	ENOG4105QUH	Domain of unknown function (DUF2088)
Tsac_0233	ENOG4105CY0	Metallo-Beta-Lactamase
Tsac_0235	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Tsac_0239	ENOG4105UQX	Mate efflux family protein
Tsac_0240	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Tsac_0242	ENOG4105C59	p-type ATPase
Tsac_0247	ENOG4105CIG	ABC transporter
Tsac_0249	ENOG4105MRR	Transcriptional regulator (By similarity)
Tsac_0250	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
Tsac_0251	ENOG4105G01	cobalamin (vitamin B12) biosynthesis CbiM protein
Tsac_0253	ENOG4108JJB	ABC transporter
Tsac_0254	ENOG4107RGD	Major Facilitator superfamily
Tsac_0262	ENOG4108HHA	Transketolase
Tsac_0265	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
Tsac_0266	ENOG4106ETB	IIa component
Tsac_0267	ENOG4105D7K	pfkb domain protein
Tsac_0269	ENOG4108M60	Transcriptional regulator
Tsac_0270	ENOG4105CY0	Metallo-Beta-Lactamase
Tsac_0272	ENOG4108HWW	ABC transporter
Tsac_0276	ENOG4105CMG	Carbohydrate kinase
Tsac_0284	ENOG4108HQ0	Exopolysaccharide biosynthesis protein
Tsac_0285	ENOG4107QW4	alcohol dehydrogenase
Tsac_0287	ENOG4107TVC	Glycosyl transferase, family 2
Tsac_0288	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
Tsac_0289	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
Tsac_0292	ENOG4105CJR	Integral membrane protein (MviN
Tsac_0293	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Tsac_0295	ENOG4105CGA	flagellar basal-body rod protein FlgG
Tsac_0298	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
Tsac_0308	ENOG4107QSE	Dipeptidase
Tsac_0309	ENOG4107SC7	Inner membrane transporter yjeM
Tsac_0311	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Tsac_0313	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
Tsac_0314	ENOG4105ESV	Glycosyl transferase, family 4
Tsac_0316	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
Tsac_0317	ENOG4108YZG	isomerase
Tsac_0318	ENOG4107WAU	Protein tyrosine phosphatase
Tsac_0319	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Tsac_0320	ENOG41081FK	Mediates zinc uptake. May also transport other divalent cations (By similarity)
Tsac_0322	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Tsac_0323	ENOG4105CBJ	Metal-dependent enzyme
Tsac_0324	ENOG4107104	thymidine kinase
Tsac_0325	ENOG41082DI	50s ribosomal protein l31
Tsac_0326	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
Tsac_0329	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
Tsac_0330	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Tsac_0332	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Tsac_0333	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Tsac_0335	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tsac_0336	ENOG4105BZ1	(ABC) transporter
Tsac_0337	ENOG4105BZ1	(ABC) transporter
Tsac_0339	ENOG4105CS2	ec 3.2.1.21
Tsac_0343	ENOG4105ETE	Transcriptional regulator (LacI family
Tsac_0346	ENOG4105DM4	PTS System
Tsac_0347	ENOG4105DM4	PTS System
Tsac_0348	ENOG4105DE4	1-phosphofructokinase
Tsac_0349	ENOG4105E98	transcriptional regulator DeoR family
Tsac_0356	ENOG4105CKK	Glycosyl transferase, family 2
Tsac_0357	ENOG4105EDW	glycosyl transferase, family 39
Tsac_0359	ENOG4105F3H	Histidine kinase
Tsac_0366	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Tsac_0371	ENOG4105C5R	Aminotransferase
Tsac_0372	ENOG4105BZW	Glycerate kinase
Tsac_0373	ENOG4105CN1	protease
Tsac_0374	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
Tsac_0375	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
Tsac_0376	ENOG4105D6E	homoserine dehydrogenase
Tsac_0377	ENOG41090I5	UPF0735 ACT domain-containing protein
Tsac_0379	ENOG4105Q2H	domain protein
Tsac_0380	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Tsac_0381	ENOG4105DQU	oxidoreductase, subunit beta
Tsac_0382	ENOG4105BZ1	(ABC) transporter
Tsac_0384	ENOG410834F	Transcriptional regulator
Tsac_0386	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Tsac_0387	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
Tsac_0395	ENOG4107YH3	SUF system FeS assembly protein, NifU family
Tsac_0397	ENOG4105DIW	FeS assembly protein SUFB
Tsac_0398	ENOG4105DIW	FeS assembly protein SUFB
Tsac_0416	ENOG4108EKI	Dehydrogenase
Tsac_0419	ENOG4105CPC	Aldo Keto reductase
Tsac_0423	ENOG4105CIZ	coA-substrate-specific enzyme activase
Tsac_0434	ENOG4105BZU	Histidine kinase
Tsac_0435	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
Tsac_0438	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Tsac_0442	ENOG4105BZU	Histidine kinase
Tsac_0443	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Tsac_0445	ENOG4108K5P	(LipO)protein
Tsac_0452	ENOG4105EQR	Transposase IS116 IS110 IS902
Tsac_0467	ENOG4105DQ6	Transposase
Tsac_0483	ENOG4108MRH	transcriptional regulatory protein
Tsac_0487	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
Tsac_0488	ENOG4105C6K	Malic enzyme
Tsac_0489	ENOG4105EQR	Transposase IS116 IS110 IS902
Tsac_0494	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
Tsac_0495	ENOG4105DRS	transport system, permease
Tsac_0496	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
Tsac_0498	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
Tsac_0501	ENOG4105EQR	Transposase IS116 IS110 IS902
Tsac_0502	ENOG4106HBX	Transcriptional Regulator AraC Family
Tsac_0503	ENOG4105C0H	protease
Tsac_0504	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Tsac_0507	ENOG4108N5B	2-phosphosulfolactate phosphatase
Tsac_0512	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Tsac_0513	ENOG4105DZ0	fad dependent oxidoreductase
Tsac_0515	ENOG4107XM3	UPF0442 protein
Tsac_0516	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
Tsac_0518	ENOG4105BZU	Histidine kinase
Tsac_0519	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Tsac_0520	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
Tsac_0521	ENOG4105CJW	magnesium transporter
Tsac_0522	ENOG4105IJJ	transcriptional regulator, crp fnr family
Tsac_0523	ENOG4105CDU	Replicative dna helicase
Tsac_0524	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Tsac_0525	ENOG4105BZR	domain protein
Tsac_0528	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Tsac_0529	ENOG4108UUM	single-stranded DNA-binding protein
Tsac_0530	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
Tsac_0531	ENOG4105VDK	protein, conserved in bacteria
Tsac_0532	ENOG4105D8X	mechanosensitive ion channel
Tsac_0534	ENOG4108ZDA	Sporulation protein YyaC
Tsac_0540	ENOG4107QW8	radical SAM domain protein
Tsac_0541	ENOG4105FA0	parb-like partition protein
Tsac_0542	ENOG4107QJE	Chromosome Partitioning Protein
Tsac_0543	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
Tsac_0545	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Tsac_0546	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Tsac_0547	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Tsac_0548	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
Tsac_0549	ENOG4107R4E	Membrane
Tsac_0550	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
Tsac_0551	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
Tsac_0552	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Tsac_0557	ENOG4105F1K	Glutamine amidotransferase
Tsac_0559	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Tsac_0560	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Tsac_0564	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
Tsac_0565	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Tsac_0567	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Tsac_0568	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Tsac_0569	ENOG4105C01	Dihydroxy-acid dehydratase
Tsac_0570	ENOG4105C7K	acetolactate synthase
Tsac_0571	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Tsac_0572	ENOG4108R6K	riboflavin synthase, subunit alpha
Tsac_0575	ENOG4108REF	Sporulation integral membrane protein ytvi
Tsac_0578	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Tsac_0580	ENOG4105DJZ	UPF0182 protein
Tsac_0583	ENOG4105DTT	CRISPR-associated helicase, cas3
Tsac_0593	ENOG4105K64	Glycosyl transferase, family 2
Tsac_0594	ENOG4105CPK	Glycosyl transferase (Group 1
Tsac_0595	ENOG4108PQP	glycosyl transferase group 1
Tsac_0598	ENOG4105EQR	Transposase IS116 IS110 IS902
Tsac_0599	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
Tsac_0611	ENOG4108Z6B	deaminase
Tsac_0612	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Tsac_0613	ENOG4105C6E	dna polymerase iii
Tsac_0614	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Tsac_0615	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
Tsac_0616	ENOG41087RV	Protein CrcB homolog
Tsac_0618	ENOG4105DHT	Metal Dependent Phosphohydrolase
Tsac_0623	ENOG4105CHR	reductase
Tsac_0628	ENOG4105C6N	Formate acetyltransferase
Tsac_0629	ENOG4105F1A	Pyruvate formate-lyase
Tsac_0630	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
Tsac_0631	ENOG4106DSS	Tartrate dehydratase subunit alpha
Tsac_0633	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Tsac_0635	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Tsac_0636	ENOG4105CXN	decarboxylase
Tsac_0637	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Tsac_0638	ENOG4105X0R	protein from nitrogen regulatory protein P-II
Tsac_0640	ENOG4107QMP	dna polymerase iii subunits gamma and tau
Tsac_0641	ENOG4105MA4	psp1 domain protein
Tsac_0645	ENOG4105CEU	Arginine dihydrolase
Tsac_0646	ENOG41060K3	Methyltransferase
Tsac_0647	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
Tsac_0649	ENOG4105KRN	Transcriptional regulator, abrb family
Tsac_0650	ENOG4108JIC	nucleoside recognition domain protein
Tsac_0653	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Tsac_0664	ENOG4105F8V	Hydrolase, tatD family
Tsac_0666	ENOG41069ER	domain protein
Tsac_0667	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Tsac_0675	ENOG4105D65	subunit l
Tsac_0677	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
Tsac_0679	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
Tsac_0680	ENOG4107X8D	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Tsac_0681	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
Tsac_0682	ENOG4107RSS	Hydrogenase accessory protein HypB
Tsac_0685	ENOG4105CQS	hydrogenase expression formation protein HypD
Tsac_0686	ENOG4105C45	hydrogenase expression formation protein (HypE)
Tsac_0689	ENOG4105C1J	atp-dependent rna helicase
Tsac_0691	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
Tsac_0694	ENOG4105EG2	ABC transporter, permease
Tsac_0695	ENOG4105CKB	glycosidase
Tsac_0702	ENOG4107VXZ	Hydrolase
Tsac_0704	ENOG410810Y	Sulfite reductase
Tsac_0705	ENOG4107SHJ	sulfite reductase subunit b
Tsac_0706	ENOG4105D5B	Sulfite reductase, subunit A
Tsac_0717	ENOG4107RR1	TRANSCRIPTIONal
Tsac_0722	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Tsac_0729	ENOG4105VN1	Heat shock protein
Tsac_0731	ENOG4105ETE	Transcriptional regulator (LacI family
Tsac_0732	ENOG4105DFU	Cell wall formation (By similarity)
Tsac_0733	ENOG4105DFT	pur operon repressor
Tsac_0735	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Tsac_0736	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Tsac_0738	ENOG4105BZU	Histidine kinase
Tsac_0739	ENOG4105C0H	protease
Tsac_0742	ENOG4108JA2	transcriptioN-repair coupling factor
Tsac_0743	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
Tsac_0744	ENOG4108M14	stage v sporulation protein t
Tsac_0745	ENOG4105XFA	sporulation peptidase YabG
Tsac_0746	ENOG4105W42	Veg protein
Tsac_0749	ENOG4105DRR	Transcriptional regulator, GntR family
Tsac_0753	ENOG4108Q8B	Spore germination protein
Tsac_0754	ENOG4108Q5U	germination protein, ger(x)c family
Tsac_0755	ENOG4108ZXQ	stage ii sporulation protein r
Tsac_0756	ENOG4105CXN	decarboxylase
Tsac_0758	ENOG4105MSI	germination protein ypeb
Tsac_0762	ENOG4105DRS	transport system, permease
Tsac_0763	ENOG4105ETE	Transcriptional regulator (LacI family
Tsac_0765	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
Tsac_0766	ENOG4105CUB	amino acid
Tsac_0767	ENOG4105CEU	Arginine dihydrolase
Tsac_0768	ENOG4105DBV	ornithine carbamoyltransferase
Tsac_0771	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
Tsac_0772	ENOG4105CPF	Cell wall formation (By similarity)
Tsac_0774	ENOG4105C75	arginyL-tRNA synthetase
Tsac_0775	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
Tsac_0776	ENOG4105CJ1	ABC, transporter
Tsac_0780	ENOG4105WH1	Two component transcriptional regulator luxr family
Tsac_0782	ENOG4105C0X	amino acid
Tsac_0784	ENOG4105CPC	Aldo Keto reductase
Tsac_0787	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
Tsac_0788	ENOG4105N67	Proton-coupled thiamine transporter YuaJ
Tsac_0790	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
Tsac_0794	ENOG4108HQ0	Exopolysaccharide biosynthesis protein
Tsac_0802	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Tsac_0803	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
Tsac_0805	ENOG4105C8Y	Acetylornithine aminotransferase
Tsac_0806	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
Tsac_0809	ENOG4105CH7	arginosuccinase
Tsac_0810	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Tsac_0811	ENOG4105DQR	SNARE associated Golgi
Tsac_0812	ENOG4105KST	dependent repressor
Tsac_0813	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
Tsac_0814	ENOG4105MAX	Superoxide reductase
Tsac_0815	ENOG4108IJ0	Aspartate ammonia-lyase
Tsac_0819	ENOG4108IY2	MazG family
Tsac_0820	ENOG4105K70	DNA-binding protein
Tsac_0821	ENOG41082I2	s4 domain protein
Tsac_0823	ENOG4105VYY	sporulation protein yabp
Tsac_0828	ENOG41060GV	RNA binding s1 domain protein
Tsac_0829	ENOG4105D49	3-dehydroquinate synthase
Tsac_0846	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
Tsac_0848	ENOG41067QW	Transcriptional regulator
Tsac_0868	ENOG4105DR5	peptidase
Tsac_0881	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
Tsac_0889	ENOG4105CKK	Glycosyl transferase, family 2
Tsac_0897	ENOG4107T94	Endo-14-beta-xylanase
Tsac_0902	ENOG4105DNE	Transposase
Tsac_0904	ENOG4105FKZ	Methyl-accepting chemotaxis
Tsac_0907	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Tsac_0911	ENOG4107QWP	ABC-2 type transporter
Tsac_0912	ENOG4105CJ1	ABC, transporter
Tsac_0914	ENOG4107Z3H	Transcriptional regulator, TetR family
Tsac_0924	ENOG4105VUC	UPF0237 protein
Tsac_0926	ENOG41089UC	methyltransferase, type 11
Tsac_0931	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Tsac_0934	ENOG4105D9P	serine threonine protein kinase
Tsac_0935	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Tsac_0936	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
Tsac_0938	ENOG4105ID8	Transcriptional regulator, ARAC family
Tsac_0940	ENOG4105BZU	Histidine kinase
Tsac_0941	ENOG4105CKU	formyltetrahydrofolate synthetase
Tsac_0943	ENOG4107QX3	carboxylase
Tsac_0945	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
Tsac_0946	ENOG4105FH5	Membrane
Tsac_0947	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
Tsac_0949	ENOG4105E1K	spore germination protein
Tsac_0955	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Tsac_0956	ENOG4105CRK	lysyL-tRNA synthetase
Tsac_0957	ENOG4105EUJ	GTP cyclohydrolase i
Tsac_0958	ENOG4105EEI	dihydropteroate synthase
Tsac_0959	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Tsac_0960	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
Tsac_0961	ENOG4105PW4	Sugar fermentation stimulation protein homolog
Tsac_0962	ENOG410867B	UPF0291 protein
Tsac_0966	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Tsac_0967	ENOG4105BZU	Histidine kinase
Tsac_0970	ENOG4105DM4	PTS System
Tsac_0971	ENOG4105DM4	PTS System
Tsac_0972	ENOG4108YRF	PTS System
Tsac_0973	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
Tsac_0974	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Tsac_0975	ENOG4105C6K	Malic enzyme
Tsac_0978	ENOG4108Z0C	Uvrb UvrC protein
Tsac_0979	ENOG41066A3	ATP guanido phosphotransferase
Tsac_0981	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Tsac_0983	ENOG4105CTP	PilT protein domain protein
Tsac_0984	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
Tsac_0986	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
Tsac_0989	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Tsac_0990	ENOG4105D7W	serine acetyltransferase
Tsac_0991	ENOG4105C8N	cysteinyl-tRNA synthetase
Tsac_0993	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Tsac_0994	ENOG4105M0M	Tetracycline resistance protein
Tsac_0996	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Tsac_0997	ENOG410683Z	Preprotein translocase SecE subunit
Tsac_0998	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
Tsac_0999	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Tsac_1002	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Tsac_1003	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Tsac_1004	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Tsac_1005	ENOG4105XPM	ribosomal protein
Tsac_1006	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Tsac_1007	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Tsac_1008	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Tsac_1009	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Tsac_1010	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Tsac_1011	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Tsac_1012	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Tsac_1013	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Tsac_1014	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Tsac_1015	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Tsac_1016	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Tsac_1017	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Tsac_1018	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Tsac_1019	ENOG41082SA	50s ribosomal protein l29
Tsac_1020	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Tsac_1021	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Tsac_1022	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Tsac_1023	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Tsac_1024	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Tsac_1025	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Tsac_1027	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Tsac_1028	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Tsac_1029	ENOG4105VPB	50S ribosomal protein L30
Tsac_1030	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Tsac_1031	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Tsac_1032	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Tsac_1035	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Tsac_1036	ENOG41067V7	50S ribosomal protein L36
Tsac_1037	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Tsac_1038	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Tsac_1039	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Tsac_1040	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Tsac_1041	ENOG4108ZT0	50S ribosomal protein l17
Tsac_1042	ENOG4108JJB	ABC transporter
Tsac_1043	ENOG4108JJB	ABC transporter
Tsac_1044	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
Tsac_1045	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Tsac_1046	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Tsac_1047	ENOG4108UJD	30S ribosomal protein S9
Tsac_1049	ENOG4108JB8	alcohol dehydrogenase
Tsac_1050	ENOG4107SMJ	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
Tsac_1055	ENOG41068JE	domain protein
Tsac_1057	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Tsac_1061	ENOG4105C8B	TIGR00159 family
Tsac_1068	ENOG4105E9Q	Acyl-transferase
Tsac_1070	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Tsac_1088	ENOG4108D32	Methyltransferase
Tsac_1089	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
Tsac_1091	ENOG4105KY5	gCN5-related N-acetyltransferase
Tsac_1112	ENOG4105KAK	Plasmid pRiA4b ORF-3 family protein
Tsac_1119	ENOG4107SXA	Phosphorylase
Tsac_1122	ENOG4105KBH	arsR family transcriptional regulator
Tsac_1127	ENOG4105D9U	N-acetyltransferase
Tsac_1128	ENOG4105K5X	acetyltransferase
Tsac_1130	ENOG410667J	hydrolase
Tsac_1131	ENOG410828M	hemerythrin-like, metal-binding protein
Tsac_1134	ENOG4105EEM	helicase
Tsac_1135	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
Tsac_1138	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Tsac_1140	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Tsac_1142	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
Tsac_1149	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
Tsac_1151	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
Tsac_1153	ENOG4105VCQ	rubredoxin
Tsac_1155	ENOG4105CK5	oxidoreductase
Tsac_1156	ENOG4107KJX	Transcriptional regulator
Tsac_1157	ENOG4107YY3	extracellular solute-binding protein family 1
Tsac_1159	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
Tsac_1163	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
Tsac_1164	ENOG4105DRS	transport system, permease
Tsac_1166	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
Tsac_1167	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Tsac_1168	ENOG4105E2V	Glycosyltransferase 36
Tsac_1169	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
Tsac_1171	ENOG4107QX8	SPFH domain, Band 7 family protein
Tsac_1173	ENOG4108IQ6	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
Tsac_1176	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
Tsac_1178	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
Tsac_1179	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
Tsac_1182	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Tsac_1183	ENOG4107YEI	lmbE family
Tsac_1184	ENOG4108IGT	Dipeptidase
Tsac_1185	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Tsac_1193	ENOG4105KTU	Transcriptional regulator, arsr family
Tsac_1197	ENOG41076QQ	Glycosyl transferase, family 2
Tsac_1198	ENOG4108X8W	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Tsac_1200	ENOG4105D6J	arsenicaL-resistance protein
Tsac_1203	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Tsac_1204	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
Tsac_1208	ENOG4108JUB	Transcriptional regulator
Tsac_1209	ENOG4105CMT	Dihydroxyacetone kinase
Tsac_1211	ENOG4105VDH	Dihydroxyacetone kinase
Tsac_1213	ENOG4105CFG	Acts as a chaperone (By similarity)
Tsac_1220	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
Tsac_1224	ENOG4105CJ1	ABC, transporter
Tsac_1227	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
Tsac_1233	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Tsac_1234	ENOG4105CBC	glutamate synthase
Tsac_1235	ENOG4105EYU	Glutamine amido-transferase
Tsac_1236	ENOG4107VHA	regulatoR
Tsac_1237	ENOG4105CAK	Cell division ATP-binding protein ftsE
Tsac_1238	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
Tsac_1239	ENOG4105DR5	peptidase
Tsac_1240	ENOG4105CN1	protease
Tsac_1242	ENOG4108N5B	2-phosphosulfolactate phosphatase
Tsac_1243	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Tsac_1245	ENOG4105HZM	Fha domain containing protein
Tsac_1247	ENOG4105CJN	penicillin-binding protein
Tsac_1250	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
Tsac_1252	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
Tsac_1253	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
Tsac_1255	ENOG4105DKQ	ROK family
Tsac_1256	ENOG4105CEY	Amp-dependent synthetase and ligase
Tsac_1257	ENOG4105ETE	Transcriptional regulator (LacI family
Tsac_1258	ENOG4105CK5	oxidoreductase
Tsac_1260	ENOG4105WZ4	isomerase
Tsac_1261	ENOG4105D9R	oxidoreductase
Tsac_1262	ENOG4105CNT	hydrolase family 2
Tsac_1263	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Tsac_1264	ENOG4105VCP	PTS System
Tsac_1265	ENOG4105CYT	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
Tsac_1269	ENOG4105CS2	ec 3.2.1.21
Tsac_1270	ENOG4105ETE	Transcriptional regulator (LacI family
Tsac_1272	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
Tsac_1276	ENOG4105C4C	beta-galactosidase
Tsac_1277	ENOG4105CJQ	hydrolase, family 31
Tsac_1278	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
Tsac_1280	ENOG4105CNN	ABC, transporter
Tsac_1281	ENOG4105C2J	ABC transporter
Tsac_1282	ENOG4105CNN	ABC, transporter
Tsac_1283	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
Tsac_1284	ENOG4105EF1	ribulokinase
Tsac_1285	ENOG4105CR5	Class II aldolase adducin family protein
Tsac_1287	ENOG4105CMD	Transcriptional regulator, GntR family
Tsac_1288	ENOG4108MDK	Dehydrogenase
Tsac_1294	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
Tsac_1295	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
Tsac_1296	ENOG4105CMR	udp-glucose 4-epimerase
Tsac_1297	ENOG4105E2R	ROK family
Tsac_1303	ENOG4105CJ2	(LipO)protein
Tsac_1305	ENOG4105CJN	penicillin-binding protein
Tsac_1306	ENOG4105DQE	DNA ligase
Tsac_1307	ENOG4105FDF	Could be involved in DNA repair (By similarity)
Tsac_1313	ENOG4105EXC	Acyl-transferase
Tsac_1314	ENOG4105D5Q	Arginine ornithine antiporter
Tsac_1315	ENOG4105CVG	Homoserine O-transsuccinylase
Tsac_1316	ENOG4107QZT	geranylgeranyl reductase
Tsac_1317	ENOG41082MP	copper ion binding protein
Tsac_1319	ENOG4105DCG	PHP domain protein
Tsac_1323	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
Tsac_1325	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Tsac_1326	ENOG4105EMN	RNA polymerase sigma factor
Tsac_1335	ENOG4105C59	p-type ATPase
Tsac_1337	ENOG4105D4A	Cell wall formation (By similarity)
Tsac_1338	ENOG4105DCG	PHP domain protein
Tsac_1339	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Tsac_1347	ENOG4105C8Q	Methyl-accepting chemotaxis
Tsac_1348	ENOG4107FKK	extracellular solute-binding protein family 1
Tsac_1349	ENOG4105D56	permease protein
Tsac_1350	ENOG4105EG2	ABC transporter, permease
Tsac_1354	ENOG4108IUK	alpha amylase, catalytic
Tsac_1357	ENOG4105CIE	May be required for sporulation (By similarity)
Tsac_1358	ENOG4105KRI	phosphocarrier protein (HPr
Tsac_1360	ENOG4105C0B	DNA polymerase III (alpha subunit)
Tsac_1362	ENOG4105CTQ	phosphohexokinase
Tsac_1366	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Tsac_1370	ENOG4105DQ6	Transposase
Tsac_1376	ENOG4107Y80	Major Facilitator superfamily
Tsac_1378	ENOG4105BZU	Histidine kinase
Tsac_1382	ENOG4108DBC	nitroreductase
Tsac_1385	ENOG4105DVT	helicase
Tsac_1387	ENOG4105EUK	rtx toxin RtxA
Tsac_1388	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
Tsac_1389	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Tsac_1390	ENOG4108RCM	Nitroreductase
Tsac_1397	ENOG4105C3R	Methionine synthase
Tsac_1398	ENOG4105WEF	catalase
Tsac_1401	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Tsac_1402	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
Tsac_1403	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
Tsac_1405	ENOG4105CPC	Aldo Keto reductase
Tsac_1410	ENOG4105VUF	Transcriptional regulator
Tsac_1411	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
Tsac_1412	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Tsac_1413	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Tsac_1414	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Tsac_1415	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Tsac_1417	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Tsac_1418	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Tsac_1419	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
Tsac_1420	ENOG41082I9	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Tsac_1421	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
Tsac_1422	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Tsac_1423	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
Tsac_1424	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
Tsac_1425	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
Tsac_1426	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Tsac_1430	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
Tsac_1432	ENOG4105D2X	ABC transporter substrate-binding protein
Tsac_1434	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
Tsac_1435	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
Tsac_1443	ENOG4107XBN	GntR Family Transcriptional Regulator
Tsac_1444	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
Tsac_1446	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
Tsac_1453	ENOG4105I82	acetyl xylan esterase
Tsac_1454	ENOG4105EQD	regulatoR
Tsac_1454	ENOG4105EQD	regulatoR
Tsac_1455	ENOG4108HRK	Histidine kinase
Tsac_1458	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
Tsac_1462	ENOG4105XN3	extracellular solute-binding protein family 1
Tsac_1463	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
Tsac_1464	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
Tsac_1468	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Tsac_1471	ENOG41069HH	4-oxalocrotonate tautomerase
Tsac_1476	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
Tsac_1478	ENOG4108K88	Membrane
Tsac_1482	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Tsac_1483	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Tsac_1486	ENOG4105CNW	domain protein
Tsac_1487	ENOG4108IFG	nitrite reductase, (NAD(P)H)
Tsac_1488	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
Tsac_1490	ENOG4108UKJ	Cdp-alcohol phosphatidyltransferase
Tsac_1492	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
Tsac_1493	ENOG4105C8M	UPF0272 protein
Tsac_1494	ENOG4105C8M	UPF0272 protein
Tsac_1495	ENOG4107ZYJ	bioY protein
Tsac_1496	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Tsac_1498	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Tsac_1503	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
Tsac_1507	ENOG4107KJX	Transcriptional regulator
Tsac_1510	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
Tsac_1511	ENOG4105DRS	transport system, permease
Tsac_1512	ENOG4105ETE	Transcriptional regulator (LacI family
Tsac_1513	ENOG4107FKK	extracellular solute-binding protein family 1
Tsac_1517	ENOG4107URF	beta-phospho-glucomutase
Tsac_1518	ENOG4108ZJ4	polysaccharide deacetylase
Tsac_1521	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
Tsac_1522	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Tsac_1523	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Tsac_1524	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
Tsac_1528	ENOG4105BZU	Histidine kinase
Tsac_1532	ENOG4105DYB	Isoaspartyl dipeptidase
Tsac_1533	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Tsac_1536	ENOG4105VRS	hydrolase family 18
Tsac_1538	ENOG4105DR5	peptidase
Tsac_1539	ENOG4107EF8	Glycosyl transferase (Group 1
Tsac_1547	ENOG4107SBE	Glycosyl transferase (Group 1
Tsac_1548	ENOG4105VPX	protein, conserved in bacteria
Tsac_1550	ENOG4105Y5S	NADH ubiquinone oxidoreductase, 24 kD
Tsac_1555	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
Tsac_1556	ENOG4105C3G	gtp-binding protein
Tsac_1563	ENOG4105CJN	penicillin-binding protein
Tsac_1564	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Tsac_1565	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
Tsac_1566	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Tsac_1568	ENOG4105CNI	cell division protein FtsW
Tsac_1569	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Tsac_1570	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Tsac_1573	ENOG4105K67	small basic protein
Tsac_1574	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
Tsac_1575	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Tsac_1577	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tsac_1578	ENOG4105E65	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tsac_1581	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Tsac_1582	ENOG4105BZU	Histidine kinase
Tsac_1583	ENOG4105CVA	phosphate
Tsac_1584	ENOG4105C8Q	Methyl-accepting chemotaxis
Tsac_1585	ENOG4105C8U	phosphate abc transporter
Tsac_1586	ENOG4105E2Z	phosphate ABC transporter (Permease
Tsac_1587	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Tsac_1588	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
Tsac_1595	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Tsac_1597	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
Tsac_1601	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
Tsac_1603	ENOG4108UVJ	appr-1-p processing domain protein
Tsac_1604	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Tsac_1606	ENOG41066FP	Small acid-soluble spore protein I
Tsac_1608	ENOG4105CNW	domain protein
Tsac_1610	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
Tsac_1611	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
Tsac_1613	ENOG4105DPN	Oligoendopeptidase f
Tsac_1615	ENOG4105EJQ	L-serine dehydratase
Tsac_1616	ENOG4105D49	3-dehydroquinate synthase
Tsac_1617	ENOG4105CQC	Prephenate dehydratase
Tsac_1618	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Tsac_1620	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Tsac_1621	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Tsac_1622	ENOG4105GR3	Histidine kinase
Tsac_1630	ENOG41066F8	ROK family
Tsac_1631	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
Tsac_1632	ENOG4107QIV	Cytochrome c biogenesis protein
Tsac_1633	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Tsac_1634	ENOG4105K63	Thioredoxin
Tsac_1636	ENOG4105EB3	Histidine kinase
Tsac_1638	ENOG4105CXN	decarboxylase
Tsac_1639	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
Tsac_1640	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Tsac_1641	ENOG4107SWG	transcriptional regulator MERR family
Tsac_1642	ENOG4105NBF	ammecr1 domain protein
Tsac_1644	ENOG4105E43	Extracellular solute-binding protein, family 5
Tsac_1649	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Tsac_1650	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
Tsac_1652	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Tsac_1653	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Tsac_1654	ENOG4105D52	delta-aminolevulinic acid dehydratase
Tsac_1656	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
Tsac_1657	ENOG4105D06	uba thif-type nad fad binding protein
Tsac_1659	ENOG4105VFE	sira family
Tsac_1661	ENOG4105C11	sulfate adenylyltransferase), subunit 2
Tsac_1662	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
Tsac_1664	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
Tsac_1669	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Tsac_1671	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
Tsac_1672	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
Tsac_1677	ENOG4105CDY	transcriptional regulatory protein
Tsac_1678	ENOG4108V3W	Chemotaxis protein, CheW
Tsac_1680	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Tsac_1681	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Tsac_1682	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Tsac_1683	ENOG41061AI	Protein of unknown function (DUF2905)
Tsac_1684	ENOG4105JFG	SpoIID LytB domain protein
Tsac_1685	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
Tsac_1686	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Tsac_1690	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Tsac_1691	ENOG4107SBW	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Tsac_1694	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Tsac_1695	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Tsac_1696	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Tsac_1698	ENOG4105C5X	domain protein
Tsac_1699	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
Tsac_1701	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Tsac_1702	ENOG4105CXT	aspartate transcarbamylase
Tsac_1703	ENOG4105CD3	dihydroorotase
Tsac_1705	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
Tsac_1706	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
Tsac_1707	ENOG4107XPQ	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Tsac_1708	ENOG4105DR4	Methyltransferase
Tsac_1711	ENOG4105F23	Fibronectin-binding protein
Tsac_1712	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
Tsac_1713	ENOG4105DSJ	YicC domain protein
Tsac_1715	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Tsac_1717	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Tsac_1718	ENOG4105C25	Primosomal protein n'
Tsac_1719	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Tsac_1720	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Tsac_1724	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Tsac_1725	ENOG4108ZF3	Phosphatase
Tsac_1726	ENOG4105D9P	serine threonine protein kinase
Tsac_1727	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
Tsac_1728	ENOG4105DJV	ribulose-phosphate 3-epimerase
Tsac_1733	ENOG4108ZSR	alkaline shock protein
Tsac_1734	ENOG4105DP4	dak2 domain fusion protein ylov
Tsac_1735	ENOG4105CB5	ATP-dependent DNA helicase recG
Tsac_1736	ENOG4105EPR	degv family
Tsac_1739	ENOG4106H78	methyltransferase
Tsac_1740	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Tsac_1742	ENOG4105H20	Sporulation integral membrane protein YlbJ
Tsac_1744	ENOG4108IJ2	phosphate acetyltransferase
Tsac_1745	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Tsac_1746	ENOG4105KNH	Nucleic acid-binding protein
Tsac_1747	ENOG41067VY	50S ribosomal protein L32
Tsac_1748	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
Tsac_1749	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
Tsac_1750	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Tsac_1751	ENOG4105EA8	2-Nitropropane dioxygenase
Tsac_1752	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
Tsac_1753	ENOG4105CHR	reductase
Tsac_1754	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Tsac_1755	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Tsac_1756	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Tsac_1757	ENOG4105D4P	Coproporphyrinogen iii oxidase
Tsac_1758	ENOG4105MCT	stage V sporulation protein S
Tsac_1759	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
Tsac_1760	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
Tsac_1761	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
Tsac_1763	ENOG4105K5M	30s ribosomal protein S16
Tsac_1764	ENOG4105VB6	UPF0109 protein
Tsac_1765	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Tsac_1766	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Tsac_1767	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Tsac_1769	ENOG4105C0P	Mg chelatase subunit ChlI
Tsac_1770	ENOG4105C31	Tryptophanyl-tRNA synthetase
Tsac_1771	ENOG4105VFF	UPF0102 protein
Tsac_1772	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Tsac_1774	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Tsac_1775	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
Tsac_1776	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
Tsac_1778	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
Tsac_1779	ENOG4108ZC9	flagellar basal-body rod protein flgc
Tsac_1780	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
Tsac_1781	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
Tsac_1782	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Tsac_1788	ENOG410822I	Flagellar hook capping protein
Tsac_1789	ENOG4105BZE	flagellar hook protein, FlgE
Tsac_1792	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Tsac_1793	ENOG4105DD5	Flagellar motor switch protein
Tsac_1794	ENOG4107YTP	response regulator receiver protein
Tsac_1796	ENOG4105CN7	Flagellar biosynthetic protein FliP
Tsac_1797	ENOG4105VS8	Flagellar biosynthetic protein fliq
Tsac_1798	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
Tsac_1799	ENOG4105D00	flagellar biosynthetic protein flhB
Tsac_1800	ENOG4105D7B	Flagellar biosynthesis protein flha
Tsac_1801	ENOG4105FZW	flagellar biosynthesis regulator FlhF
Tsac_1804	ENOG4105CBS	Chea signal transduction histidine kinase
Tsac_1805	ENOG4108V3W	Chemotaxis protein, CheW
Tsac_1807	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
Tsac_1808	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tsac_1811	ENOG4105CE9	30S ribosomal protein S2
Tsac_1812	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Tsac_1813	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Tsac_1814	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Tsac_1816	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Tsac_1817	ENOG4105KNE	Phosphatidate cytidylyltransferase
Tsac_1818	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
Tsac_1819	ENOG4105DZP	Membrane-associated zinc metalloprotease
Tsac_1820	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Tsac_1822	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
Tsac_1823	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
Tsac_1824	ENOG4105CHV	Transcription elongation factor NusA
Tsac_1827	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Tsac_1828	ENOG4105SFS	phosphoesterase RecJ domain protein
Tsac_1829	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Tsac_1830	ENOG4105DTN	riboflavin biosynthesis protein ribF
Tsac_1833	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Tsac_1834	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Tsac_1836	ENOG4105C1V	Peptidase, M16
Tsac_1837	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
Tsac_1840	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
Tsac_1842	ENOG4105CNU	cell division protein FtsK
Tsac_1843	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Tsac_1844	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
Tsac_1845	ENOG4105CEV	competence damage-inducible protein
Tsac_1846	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Tsac_1847	ENOG410902V	Modulates RecA activity (By similarity)
Tsac_1852	ENOG4105EYH	Exonuclease
Tsac_1853	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
Tsac_1854	ENOG4105D48	metallophosphoesterase
Tsac_1855	ENOG4105MCT	stage V sporulation protein S
Tsac_1856	ENOG4105DB7	PHP domain protein
Tsac_1859	ENOG4105C5S	asparaginyl-tRNA synthetase
Tsac_1860	ENOG4106F1P	AAA ATPase, central domain protein
Tsac_1861	ENOG4105CXI	aluminum resistance protein
Tsac_1862	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Tsac_1863	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Tsac_1864	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Tsac_1865	ENOG4105II7	pyrroline-5-carboxylate reductase
Tsac_1866	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
Tsac_1867	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Tsac_1868	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Tsac_1869	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Tsac_1872	ENOG4105BZU	Histidine kinase
Tsac_1873	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
Tsac_1874	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Tsac_1875	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
Tsac_1877	ENOG4105CAT	Cytidine monophosphate kinase
Tsac_1879	ENOG4105CBX	hi0933 family
Tsac_1881	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
Tsac_1882	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Tsac_1884	ENOG4106678	morphogenetic protein associated with SpoVID
Tsac_1885	ENOG4107QSA	Oxaloacetate decarboxylase
Tsac_1886	ENOG4105CYW	agmatinase
Tsac_1887	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
Tsac_1889	ENOG4105FE9	pseudouridine synthase
Tsac_1890	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Tsac_1892	ENOG4105DZ1	carboxypeptidase
Tsac_1893	ENOG4105KBJ	sporulation protein ytfj
Tsac_1895	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
Tsac_1896	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
Tsac_1897	ENOG4108Z4T	Peptidase M50
Tsac_1898	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Tsac_1901	ENOG41090VF	Stage v sporulation protein ac
Tsac_1902	ENOG41084UG	Pfam:DUF1458
Tsac_1904	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tsac_1905	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
Tsac_1906	ENOG41082AN	stage II sporulation protein
Tsac_1907	ENOG4105DZ1	carboxypeptidase
Tsac_1908	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Tsac_1909	ENOG4105MZ9	stage II sporulation protein m
Tsac_1911	ENOG4108YZ4	nudix hydrolase
Tsac_1917	ENOG4107QQR	Sporulation
Tsac_1918	ENOG4105S1Z	Stage IV sporulation protein B
Tsac_1919	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Tsac_1920	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
Tsac_1921	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Tsac_1922	ENOG4105DX0	Hemolysin A
Tsac_1923	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Tsac_1925	ENOG4105CTB	Polyprenyl synthetase
Tsac_1926	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Tsac_1927	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Tsac_1928	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Tsac_1929	ENOG4105M7K	Involved in the transcription termination process (By similarity)
Tsac_1930	ENOG4108ZSR	alkaline shock protein
Tsac_1933	ENOG410644B	Stage III sporulation protein af
Tsac_1935	ENOG4105KQ4	Stage iii sporulation protein ad
Tsac_1938	ENOG4105CD2	stage iii sporulation protein aa
Tsac_1940	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Tsac_1941	ENOG4105DC7	peptidase M24
Tsac_1942	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
Tsac_1943	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
Tsac_1944	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
Tsac_1945	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Tsac_1954	ENOG4106A3R	peptidase
Tsac_1956	ENOG4105D7Q	type ii secretion system
Tsac_1957	ENOG4105CZX	twitching motility protein
Tsac_1958	ENOG4107QHF	type ii secretion system protein e
Tsac_1959	ENOG4105E2X	shikimate dehydrogenase
Tsac_1961	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tsac_1962	ENOG4105VTR	Integrase
Tsac_1968	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Tsac_1970	ENOG4107XRG	penicillin-binding protein
Tsac_1971	ENOG4105CFP	Peptidase U32
Tsac_1972	ENOG4108VQJ	O-methyltransferase
Tsac_1974	ENOG41084CE	UPF0342 protein
Tsac_1975	ENOG4105CN5	Metallo-Beta-Lactamase
Tsac_1976	ENOG4105I3K	Ferric uptake regulator, Fur family
Tsac_1977	ENOG41068XD	UPF0473 protein
Tsac_1979	ENOG4105VBH	UPF0297 protein
Tsac_1980	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Tsac_1991	ENOG4105D1H	recombination factor protein RarA
Tsac_1996	ENOG4105K63	Thioredoxin
Tsac_1997	ENOG4105VPX	protein, conserved in bacteria
Tsac_1998	ENOG4105CUZ	uba thif-type nad fad binding protein
Tsac_2000	ENOG4105CUT	histidyl-tRNA synthetase
Tsac_2001	ENOG4105C34	Pseudouridine synthase
Tsac_2002	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Tsac_2004	ENOG4105CV1	Transketolase (EC 2.2.1.1)
Tsac_2008	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Tsac_2012	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Tsac_2013	ENOG4108I0Q	anthranilate phosphoribosyltransferase
Tsac_2014	ENOG4105DDQ	anthranilate synthase
Tsac_2015	ENOG4105CRQ	synthase (Component I)
Tsac_2020	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Tsac_2023	ENOG4105DBK	s4 domain protein
Tsac_2025	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
Tsac_2026	ENOG4105DFA	alanine racemase domain protein
Tsac_2028	ENOG4105EP9	oxidoreductase
Tsac_2031	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
Tsac_2038	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Tsac_2039	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
Tsac_2040	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
Tsac_2044	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Tsac_2045	ENOG4107YR5	Diacylglycerol kinase
Tsac_2046	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
Tsac_2047	ENOG4105CTJ	Metal Dependent Phosphohydrolase
Tsac_2048	ENOG4105C9A	Phoh family
Tsac_2050	ENOG41068P3	sporulation protein YqfC
Tsac_2051	ENOG4105KTH	gatB Yqey
Tsac_2052	ENOG4105VCC	30S ribosomal protein S21
Tsac_2053	ENOG4107YU2	histidine triad (hIT) protein
Tsac_2054	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Tsac_2055	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
Tsac_2056	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Tsac_2057	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Tsac_2058	ENOG4105CFG	Acts as a chaperone (By similarity)
Tsac_2059	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Tsac_2061	ENOG4105CSA	Coproporphyrinogen iii oxidase
Tsac_2062	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Tsac_2064	ENOG4105CPK	Glycosyl transferase (Group 1
Tsac_2068	ENOG4105CEF	Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity)
Tsac_2070	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
Tsac_2072	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
Tsac_2073	ENOG4107XDQ	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Tsac_2074	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Tsac_2077	ENOG4105CJ1	ABC, transporter
Tsac_2082	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Tsac_2083	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Tsac_2084	ENOG41084EF	Ferredoxin
Tsac_2085	ENOG4105BZ8	glutamate synthase
Tsac_2086	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
Tsac_2088	ENOG4105BZ7	extracellular solute-binding protein family 1
Tsac_2089	ENOG4105DRS	transport system, permease
Tsac_2091	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
Tsac_2093	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Tsac_2094	ENOG4108W5N	phosphatidylglycerophosphatase a
Tsac_2095	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Tsac_2097	ENOG4105KQC	Competence protein
Tsac_2098	ENOG4105DZ1	carboxypeptidase
Tsac_2100	ENOG4105WWK	YheO domain protein
Tsac_2102	ENOG4108WF2	Metal Dependent Phosphohydrolase
Tsac_2103	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Tsac_2104	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Tsac_2106	ENOG4105K46	50S ribosomal protein l27
Tsac_2108	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Tsac_2109	ENOG4105C03	ribonuclease
Tsac_2113	ENOG4108K5P	(LipO)protein
Tsac_2114	ENOG4108Z5K	methylglyoxal synthase
Tsac_2115	ENOG4105CNI	cell division protein FtsW
Tsac_2116	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
Tsac_2117	ENOG4107QMS	site-determining protein
Tsac_2118	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
Tsac_2122	ENOG4105DFF	Rod shape-determining protein mreb
Tsac_2123	ENOG4105W5Q	DNA repair protein (RadC
Tsac_2124	ENOG4108Z03	MAF-like protein
Tsac_2126	ENOG4107QHI	-hydrogenase
Tsac_2127	ENOG4107QIZ	NADH dehydrogenase
Tsac_2129	ENOG4106AFQ	Histidine kinase
Tsac_2130	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
Tsac_2133	ENOG4108R3D	Electron transport complex
Tsac_2137	ENOG4105E4C	Lytic transglycosylase catalytic
Tsac_2138	ENOG4105CI3	gtp-binding protein typa
Tsac_2139	ENOG4107TT5	NLP P60 protein
Tsac_2142	ENOG4108VMM	UPF0756 membrane protein
Tsac_2143	ENOG4105E4C	Lytic transglycosylase catalytic
Tsac_2144	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Tsac_2147	ENOG4105EMN	RNA polymerase sigma factor
Tsac_2150	ENOG4105C85	amino acid
Tsac_2151	ENOG41067S9	phage shock protein C, PspC
Tsac_2152	ENOG4105VRS	hydrolase family 18
Tsac_2155	ENOG41082MP	copper ion binding protein
Tsac_2156	ENOG4105IJJ	transcriptional regulator, crp fnr family
Tsac_2157	ENOG4108UIC	UPF0340 protein
Tsac_2158	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Tsac_2161	ENOG4105DQU	oxidoreductase, subunit beta
Tsac_2162	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Tsac_2164	ENOG4105D9Q	decarboxylase (Beta subunit)
Tsac_2166	ENOG4108ZVT	methylmalonyl-coA epimerase
Tsac_2168	ENOG4105D5P	Methylmalonyl-coA mutase
Tsac_2170	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
Tsac_2171	ENOG4105HDK	L-asparaginase
Tsac_2172	ENOG4105D82	Glutamate dehydrogenase
Tsac_2173	ENOG4105DC7	peptidase M24
Tsac_2174	ENOG4107SC7	Inner membrane transporter yjeM
Tsac_2181	ENOG4105CKM	Branched-chain carboxylic acid kinase
Tsac_2183	ENOG4107RE7	phosphate butyryltransferase
Tsac_2187	ENOG4105K4I	Scp-like extracellular
Tsac_2188	ENOG4105DFM	M18 family aminopeptidase
Tsac_2189	ENOG4105WH1	Two component transcriptional regulator luxr family
Tsac_2192	ENOG4105C98	muts2 protein
Tsac_2193	ENOG4105CFP	Peptidase U32
Tsac_2195	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Tsac_2196	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Tsac_2197	ENOG4108RWN	rrna methyltransferase
Tsac_2198	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Tsac_2199	ENOG4105VJV	50s ribosomal protein L35
Tsac_2200	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Tsac_2201	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Tsac_2203	ENOG4105C22	threonyL-tRNA synthetase
Tsac_2204	ENOG4108UH6	UPF0754 membrane protein
Tsac_2204	ENOG4108UH6	UPF0754 membrane protein
Tsac_2207	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Tsac_2208	ENOG4105CS2	ec 3.2.1.21
Tsac_2210	ENOG4105CAQ	asparagine synthetase
Tsac_2211	ENOG4105C8Q	Methyl-accepting chemotaxis
Tsac_2212	ENOG4108YZA	Nitrogen regulatory protein pii
Tsac_2215	ENOG4105BZU	Histidine kinase
Tsac_2218	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
Tsac_2220	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
Tsac_2221	ENOG4108K8K	Transcriptional regulator
Tsac_2223	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
Tsac_2225	ENOG4105E0C	molybdate abc transporter
Tsac_2226	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
Tsac_2227	ENOG4108IV0	ABC, transporter
Tsac_2228	ENOG4105C0Z	ABC transporter
Tsac_2229	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Tsac_2230	ENOG4105C32	Amino acid ABC transporter (Permease)
Tsac_2235	ENOG4108YZA	Nitrogen regulatory protein pii
Tsac_2240	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
Tsac_2241	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
Tsac_2242	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
Tsac_2245	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Tsac_2248	ENOG4105DWF	phosphomethylpyrimidine kinase
Tsac_2250	ENOG4105BZ1	(ABC) transporter
Tsac_2258	ENOG4105BZ7	extracellular solute-binding protein family 1
Tsac_2259	ENOG4105ETE	Transcriptional regulator (LacI family
Tsac_2260	ENOG4107SCA	Formamidase (EC 3.5.1.49)
Tsac_2261	ENOG4105CUB	amino acid
Tsac_2262	ENOG4108TVT	permease
Tsac_2263	ENOG4105BZU	Histidine kinase
Tsac_2267	ENOG4105DA5	(ABC) transporter
Tsac_2270	ENOG4105DY9	regulatoR
Tsac_2271	ENOG4108HRK	Histidine kinase
Tsac_2277	ENOG4105C0D	helicase
Tsac_2282	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Tsac_2283	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tsac_2285	ENOG4108MK9	spermidine N(1)-acetyltransferase
Tsac_2289	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
Tsac_2292	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Tsac_2294	ENOG4105DRS	transport system, permease
Tsac_2295	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
Tsac_2296	ENOG4105XN3	extracellular solute-binding protein family 1
Tsac_2298	ENOG4106KNT	transcriptional regulator
Tsac_2299	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
Tsac_2301	ENOG4107YGS	glycoside hydrolase 15-related
Tsac_2302	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
Tsac_2303	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
Tsac_2313	ENOG4105D2N	Aldolase
Tsac_2314	ENOG4105DT3	PTS system, galactitol-specific IIc component
Tsac_2315	ENOG4105K18	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
Tsac_2317	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Tsac_2320	ENOG4105CKB	glycosidase
Tsac_2321	ENOG4105CKB	glycosidase
Tsac_2324	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
Tsac_2326	ENOG4105ETE	Transcriptional regulator (LacI family
Tsac_2328	ENOG4105HY2	Glycosidase related protein
Tsac_2329	ENOG4105DFY	n-acylglucosamine 2-epimerase
Tsac_2330	ENOG4105ETE	Transcriptional regulator (LacI family
Tsac_2332	ENOG4105V9V	Short-chain dehydrogenase reductase Sdr
Tsac_2333	ENOG4108ZVT	methylmalonyl-coA epimerase
Tsac_2336	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Tsac_2338	ENOG4105C1A	potassium transporter peripheral membrane
Tsac_2342	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
Tsac_2344	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Tsac_2345	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Tsac_2349	ENOG4105C0H	protease
Tsac_2350	ENOG4105C4B	ABC transporter, permease
Tsac_2351	ENOG4108T5I	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Tsac_2352	ENOG4107RDB	Major Facilitator
Tsac_2354	ENOG4105BZU	Histidine kinase
Tsac_2355	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Tsac_2357	ENOG4107YM4	Beta-lactamase domain-containing protein
Tsac_2359	ENOG4107U53	septum site-determining protein minD
Tsac_2360	ENOG4105D1F	ATP-binding protein
Tsac_2362	ENOG4107QW8	radical SAM domain protein
Tsac_2364	ENOG4108JYZ	YitT family
Tsac_2368	ENOG41060CR	
Tsac_2370	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Tsac_2371	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Tsac_2373	ENOG4105CNI	cell division protein FtsW
Tsac_2374	ENOG4105DR5	peptidase
Tsac_2375	ENOG4107YEI	lmbE family
Tsac_2377	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
Tsac_2381	ENOG4107ZTW	SNARE associated Golgi
Tsac_2382	ENOG4105BZU	Histidine kinase
Tsac_2383	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Tsac_2384	ENOG4105BZU	Histidine kinase
Tsac_2385	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
Tsac_2386	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
Tsac_2387	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
Tsac_2388	ENOG4105C08	Histidine kinase
Tsac_2391	ENOG4105BZ4	penicillin-binding protein
Tsac_2392	ENOG4105CAQ	asparagine synthetase
Tsac_2396	ENOG4105CJR	Integral membrane protein (MviN
Tsac_2397	ENOG4105XXY	Thioredoxin
Tsac_2406	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Tsac_2410	ENOG4107YXZ	hydrolase, family 25
Tsac_2453	ENOG4108IMY	Transcriptional regulator
Tsac_2456	ENOG4105VTR	Integrase
Tsac_2457	ENOG4105VEQ	Cold shock protein
Tsac_2458	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Tsac_2461	ENOG41083MR	nifu domain-containing protein
Tsac_2462	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Tsac_2464	ENOG4108V0P	LemA family
Tsac_2465	ENOG4108ZGC	gaf domain protein
Tsac_2466	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Tsac_2471	ENOG4105DG6	mannose-6-phosphate isomerase
Tsac_2472	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
Tsac_2473	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Tsac_2474	ENOG4105EGD	dinuclear metal center protein, YbgI family
Tsac_2476	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tsac_2477	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Tsac_2478	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
Tsac_2479	ENOG4105XZU	Preprotein translocase, subunit SecG
Tsac_2480	ENOG4105VYW	UPF0251 protein
Tsac_2482	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Tsac_2483	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Tsac_2484	ENOG4105CP7	Triose-phosphate isomerase
Tsac_2485	ENOG4105BZA	Phosphoglycerate kinase
Tsac_2488	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tsac_2489	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
Tsac_2490	ENOG410667J	hydrolase
Tsac_2491	ENOG4105G5W	regulator Fur family
Tsac_2492	ENOG41073R8	VanW family
Tsac_2494	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
Tsac_2495	ENOG4105DAN	ATP-dependent protease
Tsac_2497	ENOG410688J	Ferredoxin
Tsac_2501	ENOG4105C22	threonyL-tRNA synthetase
Tsac_2503	ENOG4108IQ3	PTS system
Tsac_2504	ENOG4105F3R	pts system mannose fructose sorbose family iid
Tsac_2506	ENOG4108EQA	pts system
Tsac_2507	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Tsac_2508	ENOG4105C5I	Dehydrogenase
Tsac_2509	ENOG4105KY8	Rubrerythrin
Tsac_2523	ENOG4105EMS	pseudouridine synthase
Tsac_2527	ENOG4105C4R	Atp-dependent dna helicase
Tsac_2529	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Tsac_2530	ENOG4105CZV	ABC transporter
Tsac_2534	ENOG4105CZ9	Domain of unknown function (DU1801)
Tsac_2536	ENOG4108TVJ	Nitroreductase
Tsac_2538	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
Tsac_2540	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
Tsac_2541	ENOG4105ECB	domain protein
Tsac_2544	ENOG4107TVC	Glycosyl transferase, family 2
Tsac_2547	ENOG4105EJ9	Membrane
Tsac_2548	ENOG4105BZ1	(ABC) transporter
Tsac_2551	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
Tsac_2552	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Tsac_2553	ENOG4108JQ7	(ABC) transporter
Tsac_2555	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Tsac_2556	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Tsac_2557	ENOG4108J59	Extracellular solute-binding protein, family 5
Tsac_2558	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Tsac_2560	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Tsac_2563	ENOG4105KGF	protein, YerC YecD
Tsac_2564	ENOG4105VCP	PTS System
Tsac_2565	ENOG4105CK1	PTS System
Tsac_2568	ENOG4105ETD	TRANSCRIPTIONal
Tsac_2569	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
Tsac_2570	ENOG4108UMI	ABC transporter, permease
Tsac_2571	ENOG4105D01	(LipO)protein
Tsac_2573	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
Tsac_2575	ENOG4105CH2	amidohydrolase
Tsac_2576	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Tsac_2577	ENOG4107QNG	Phosphoribosylglycinamide synthetase
Tsac_2578	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Tsac_2579	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Tsac_2580	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Tsac_2582	ENOG4105C8V	SAICAR synthetase
Tsac_2583	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Tsac_2584	ENOG4105C7N	Xanthine uracil vitamin C permease
Tsac_2587	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Tsac_2588	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Tsac_2589	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Tsac_2597	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
Tsac_2599	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Tsac_2600	ENOG4105C7J	ABC transporter, permease
Tsac_2603	ENOG4105C32	Amino acid ABC transporter (Permease)
Tsac_2604	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Tsac_2605	ENOG4105C0Z	ABC transporter
Tsac_2606	ENOG4108IV0	ABC, transporter
Tsac_2608	ENOG4108UQV	Membrane
Tsac_2613	ENOG4108VAC	response regulator
Tsac_2614	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
Tsac_2616	ENOG4105ER2	Ompa motb domain protein
Tsac_2617	ENOG4107R0U	MotA TolQ exbB proton channel
Tsac_2618	ENOG4105C5H	ABC transporter
Tsac_2620	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Tsac_2621	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
Tsac_2622	ENOG41072GX	Peptidase M22 Glycoprotease
Tsac_2623	ENOG4105K8N	protein family UPF0079, ATPase
Tsac_2626	ENOG4105DBV	ornithine carbamoyltransferase
Tsac_2629	ENOG4107S1Q	Phosphatase
Tsac_2631	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
Tsac_2632	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Tsac_2633	ENOG4108JJB	ABC transporter
Tsac_2634	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
Tsac_2636	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
Tsac_2638	ENOG4105E4R	Precorrin-3B C17-methyltransferase
Tsac_2639	ENOG4108P62	biosynthesis protein (CbiG)
Tsac_2640	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
Tsac_2641	ENOG4105DVK	Precorrin-2 c20-methyltransferase
Tsac_2642	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
Tsac_2643	ENOG4108DR9	Cobalt-precorrin-6Y C(5)-methyltransferase
Tsac_2645	ENOG41081F0	Precorrin-8x methylmutase
Tsac_2646	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
Tsac_2648	ENOG4108Z3G	3H domain protein
Tsac_2650	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Tsac_2653	ENOG4105CDA	abc transporter atp-binding protein
Tsac_2654	ENOG4105E5Q	amino acid AbC transporter
Tsac_2655	ENOG4108HW3	(ABC) transporter
Tsac_2658	ENOG4105MQ3	flagellar protein FliS
Tsac_2659	ENOG4107RT6	flagellar hook-associated
Tsac_2667	ENOG4105MME	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family
Tsac_2668	ENOG4105D2T	synthase
Tsac_2669	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
Tsac_2670	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Tsac_2672	ENOG41090QV	Protein of unknown function DUF115
Tsac_2674	ENOG4105I03	Flagellin
Tsac_2675	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
Tsac_2676	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
Tsac_2678	ENOG4105DTJ	flagellar hook-associated protein
Tsac_2679	ENOG4105E1Q	flagellar hook-associated protein
Tsac_2683	ENOG4105MJ2	Competence protein
Tsac_2684	ENOG4105C7H	Helicase, RecD TraA family
Tsac_2689	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Tsac_2708	ENOG4106A3R	peptidase
Tsac_2713	ENOG4105EQR	Transposase IS116 IS110 IS902
Tsac_2727	ENOG4105C7H	Helicase, RecD TraA family
Tsac_2743	ENOG4105E0Y	RtcB Protein
Tsac_2748	ENOG4105CQR	helicase
Tsac_2752	ENOG4105YB8	TM2 domain containing protein
Tsac_2762	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Tsac_2780	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Tsac_2795	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
Tsac_2800	ENOG4105CNU	cell division protein FtsK
Tsac_2805	ENOG4105K70	DNA-binding protein
Tsac_2813	ENOG4108UUM	single-stranded DNA-binding protein
Tsac_2819	ENOG41065RQ	ADP-ribosylation crystallin J1
Tsac_2824	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Tsac_2862	ENOG4105IG6	Phage terminase, large subunit