locus-tag	class	description
Thexy_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Thexy_0003	ENOG410848D	S4 domain protein YaaA
Thexy_0006	ENOG4105F1K	Glutamine amidotransferase
Thexy_0008	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Thexy_0009	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Thexy_0014	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Thexy_0016	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Thexy_0017	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Thexy_0018	ENOG4105C01	Dihydroxy-acid dehydratase
Thexy_0019	ENOG4105C7K	acetolactate synthase
Thexy_0020	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Thexy_0021	ENOG4108R6K	riboflavin synthase, subunit alpha
Thexy_0024	ENOG4108REF	Sporulation integral membrane protein ytvi
Thexy_0027	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Thexy_0028	ENOG4108KGH	TRANSCRIPTIONal
Thexy_0029	ENOG4105DJZ	UPF0182 protein
Thexy_0032	ENOG4105BZU	Histidine kinase
Thexy_0035	ENOG4105C8Q	Methyl-accepting chemotaxis
Thexy_0036	ENOG4108V3W	Chemotaxis protein, CheW
Thexy_0037	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Thexy_0039	ENOG4105BZU	Histidine kinase
Thexy_0040	ENOG4105BZU	Histidine kinase
Thexy_0042	ENOG4105EKQ	RNA-directed DNA polymerase
Thexy_0044	ENOG4108Z6B	deaminase
Thexy_0045	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Thexy_0046	ENOG4105C6E	dna polymerase iii
Thexy_0047	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Thexy_0048	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
Thexy_0049	ENOG4105WMR	Protein CrcB homolog
Thexy_0050	ENOG4105WMR	Protein CrcB homolog
Thexy_0051	ENOG4105DHT	Metal Dependent Phosphohydrolase
Thexy_0057	ENOG4105CHR	reductase
Thexy_0062	ENOG4105C6N	Formate acetyltransferase
Thexy_0063	ENOG4105F1A	Pyruvate formate-lyase
Thexy_0065	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
Thexy_0066	ENOG4106DSS	Tartrate dehydratase subunit alpha
Thexy_0068	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Thexy_0071	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Thexy_0073	ENOG4105CXN	decarboxylase
Thexy_0074	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Thexy_0075	ENOG4105X0R	protein from nitrogen regulatory protein P-II
Thexy_0077	ENOG4107QMP	dna polymerase iii subunits gamma and tau
Thexy_0078	ENOG4105MA4	psp1 domain protein
Thexy_0082	ENOG4105CEU	Arginine dihydrolase
Thexy_0083	ENOG41060K3	Methyltransferase
Thexy_0084	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
Thexy_0086	ENOG4105KRN	Transcriptional regulator, abrb family
Thexy_0087	ENOG4108JIC	nucleoside recognition domain protein
Thexy_0090	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Thexy_0091	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
Thexy_0092	ENOG4105CZV	ABC transporter
Thexy_0095	ENOG4105F8V	Hydrolase, tatD family
Thexy_0097	ENOG41069ER	domain protein
Thexy_0098	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Thexy_0106	ENOG4105D65	subunit l
Thexy_0108	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
Thexy_0110	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
Thexy_0111	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Thexy_0112	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
Thexy_0113	ENOG4107RSS	Hydrogenase accessory protein HypB
Thexy_0116	ENOG4105CQS	hydrogenase expression formation protein HypD
Thexy_0117	ENOG4105C45	hydrogenase expression formation protein (HypE)
Thexy_0122	ENOG4107VXZ	Hydrolase
Thexy_0140	ENOG4105VN1	Heat shock protein
Thexy_0142	ENOG4105ETE	Transcriptional regulator (LacI family
Thexy_0143	ENOG4105DFU	Cell wall formation (By similarity)
Thexy_0144	ENOG4105DFT	pur operon repressor
Thexy_0146	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Thexy_0147	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Thexy_0149	ENOG4105BZU	Histidine kinase
Thexy_0150	ENOG4105C0H	protease
Thexy_0153	ENOG4108JA2	transcriptioN-repair coupling factor
Thexy_0154	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
Thexy_0155	ENOG4108M14	stage v sporulation protein t
Thexy_0156	ENOG4105XFA	sporulation peptidase YabG
Thexy_0157	ENOG4105W42	Veg protein
Thexy_0159	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Thexy_0160	ENOG4105DRR	Transcriptional regulator, GntR family
Thexy_0164	ENOG4108Q8B	Spore germination protein
Thexy_0165	ENOG4108Q5U	germination protein, ger(x)c family
Thexy_0166	ENOG4108ZXQ	stage ii sporulation protein r
Thexy_0167	ENOG4105CXN	decarboxylase
Thexy_0169	ENOG4105MSI	germination protein ypeb
Thexy_0171	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
Thexy_0172	ENOG4105CUB	amino acid
Thexy_0173	ENOG4105CEU	Arginine dihydrolase
Thexy_0174	ENOG4105DBV	ornithine carbamoyltransferase
Thexy_0177	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
Thexy_0178	ENOG4105CPF	Cell wall formation (By similarity)
Thexy_0180	ENOG4105C75	arginyL-tRNA synthetase
Thexy_0181	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
Thexy_0184	ENOG4105C0X	amino acid
Thexy_0186	ENOG4105CPC	Aldo Keto reductase
Thexy_0188	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
Thexy_0189	ENOG4105N67	Proton-coupled thiamine transporter YuaJ
Thexy_0190	ENOG4105EKQ	RNA-directed DNA polymerase
Thexy_0191	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
Thexy_0192	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
Thexy_0195	ENOG4105C0D	helicase
Thexy_0202	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Thexy_0203	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
Thexy_0205	ENOG4105C8Y	Acetylornithine aminotransferase
Thexy_0206	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
Thexy_0209	ENOG4105CH7	arginosuccinase
Thexy_0211	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Thexy_0212	ENOG4105DQR	SNARE associated Golgi
Thexy_0213	ENOG4105KST	dependent repressor
Thexy_0214	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
Thexy_0215	ENOG4105MAX	Superoxide reductase
Thexy_0216	ENOG4108IJ0	Aspartate ammonia-lyase
Thexy_0217	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Thexy_0220	ENOG4108IY2	MazG family
Thexy_0221	ENOG4105K70	DNA-binding protein
Thexy_0222	ENOG41082I2	s4 domain protein
Thexy_0224	ENOG4105VYY	sporulation protein yabp
Thexy_0229	ENOG41060GV	RNA binding s1 domain protein
Thexy_0230	ENOG4107R33	ppx gppa phosphatase
Thexy_0235	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Thexy_0241	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
Thexy_0248	ENOG41089UC	methyltransferase, type 11
Thexy_0253	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Thexy_0256	ENOG4105D9P	serine threonine protein kinase
Thexy_0257	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Thexy_0258	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Thexy_0260	ENOG4105ID8	Transcriptional regulator, ARAC family
Thexy_0262	ENOG4105BZU	Histidine kinase
Thexy_0263	ENOG4105CKU	formyltetrahydrofolate synthetase
Thexy_0265	ENOG4107QX3	carboxylase
Thexy_0268	ENOG4105FH5	Membrane
Thexy_0269	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
Thexy_0271	ENOG4105E1K	spore germination protein
Thexy_0277	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Thexy_0278	ENOG4105CRK	lysyL-tRNA synthetase
Thexy_0279	ENOG4105EUJ	GTP cyclohydrolase i
Thexy_0280	ENOG4105EEI	dihydropteroate synthase
Thexy_0281	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Thexy_0282	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
Thexy_0283	ENOG4105PW4	Sugar fermentation stimulation protein homolog
Thexy_0284	ENOG410867B	UPF0291 protein
Thexy_0288	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Thexy_0289	ENOG4105BZU	Histidine kinase
Thexy_0292	ENOG4105DM4	PTS System
Thexy_0293	ENOG4105DM4	PTS System
Thexy_0294	ENOG4108YRF	PTS System
Thexy_0295	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
Thexy_0296	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Thexy_0297	ENOG4105C6K	Malic enzyme
Thexy_0300	ENOG4108Z0C	Uvrb UvrC protein
Thexy_0301	ENOG41066A3	ATP guanido phosphotransferase
Thexy_0303	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Thexy_0305	ENOG4105CTP	PilT protein domain protein
Thexy_0306	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
Thexy_0308	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
Thexy_0311	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Thexy_0312	ENOG4105D7W	serine acetyltransferase
Thexy_0313	ENOG4105C8N	cysteinyl-tRNA synthetase
Thexy_0315	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Thexy_0316	ENOG4105M0M	Tetracycline resistance protein
Thexy_0318	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Thexy_0319	ENOG4105WDJ	50S ribosomal protein L33
Thexy_0320	ENOG410683Z	Preprotein translocase SecE subunit
Thexy_0321	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
Thexy_0322	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Thexy_0325	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Thexy_0326	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Thexy_0327	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Thexy_0328	ENOG4105XPM	ribosomal protein
Thexy_0329	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Thexy_0330	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Thexy_0331	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Thexy_0332	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Thexy_0333	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Thexy_0334	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Thexy_0335	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Thexy_0336	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Thexy_0337	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Thexy_0338	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Thexy_0339	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Thexy_0340	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Thexy_0341	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Thexy_0342	ENOG41082SA	50s ribosomal protein l29
Thexy_0343	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Thexy_0344	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Thexy_0345	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Thexy_0346	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Thexy_0347	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Thexy_0348	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Thexy_0350	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Thexy_0351	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Thexy_0352	ENOG4105VPB	50S ribosomal protein L30
Thexy_0353	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Thexy_0354	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Thexy_0355	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Thexy_0358	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Thexy_0359	ENOG41067V7	50S ribosomal protein L36
Thexy_0360	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Thexy_0361	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Thexy_0362	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Thexy_0363	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Thexy_0364	ENOG4108ZT0	50S ribosomal protein l17
Thexy_0365	ENOG4108JJB	ABC transporter
Thexy_0366	ENOG4108JJB	ABC transporter
Thexy_0367	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
Thexy_0368	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Thexy_0369	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Thexy_0370	ENOG4108UJD	30S ribosomal protein S9
Thexy_0372	ENOG4105C0A	alcohol dehydrogenase
Thexy_0373	ENOG4107SMJ	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
Thexy_0378	ENOG41068JE	domain protein
Thexy_0380	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Thexy_0384	ENOG4105C8B	TIGR00159 family
Thexy_0391	ENOG4105E9Q	Acyl-transferase
Thexy_0394	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Thexy_0404	ENOG4108YM7	Gcn5-related n-acetyltransferase
Thexy_0405	ENOG4105D9U	N-acetyltransferase
Thexy_0406	ENOG4105K5X	acetyltransferase
Thexy_0408	ENOG410667J	hydrolase
Thexy_0409	ENOG410828M	hemerythrin-like, metal-binding protein
Thexy_0412	ENOG4105EEM	helicase
Thexy_0413	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
Thexy_0416	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Thexy_0418	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Thexy_0420	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
Thexy_0428	ENOG4108K9K	Uncharacterised protein family (UPF0236)
Thexy_0429	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
Thexy_0430	ENOG4108IYU	L-aspartate oxidase
Thexy_0431	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
Thexy_0433	ENOG4105VCQ	rubredoxin
Thexy_0437	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Thexy_0439	ENOG4105E2V	Glycosyltransferase 36
Thexy_0440	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
Thexy_0442	ENOG4107QX8	SPFH domain, Band 7 family protein
Thexy_0444	ENOG4108IQ6	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
Thexy_0445	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
Thexy_0446	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
Thexy_0447	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Thexy_0448	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
Thexy_0449	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
Thexy_0452	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Thexy_0454	ENOG4108IGT	Dipeptidase
Thexy_0455	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Thexy_0463	ENOG4105KTU	Transcriptional regulator, arsr family
Thexy_0468	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Thexy_0472	ENOG4105CIZ	coA-substrate-specific enzyme activase
Thexy_0473	ENOG4105PGM	cation diffusion facilitator family transporter
Thexy_0475	ENOG4108X8W	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Thexy_0477	ENOG4105D6J	arsenicaL-resistance protein
Thexy_0480	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Thexy_0481	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
Thexy_0485	ENOG4108JUB	Transcriptional regulator
Thexy_0486	ENOG4105CMT	Dihydroxyacetone kinase
Thexy_0488	ENOG4105VDH	Dihydroxyacetone kinase
Thexy_0490	ENOG4105CFG	Acts as a chaperone (By similarity)
Thexy_0497	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
Thexy_0501	ENOG4105CJ1	ABC, transporter
Thexy_0505	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
Thexy_0506	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
Thexy_0511	ENOG4108IFG	nitrite reductase, (NAD(P)H)
Thexy_0512	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Thexy_0513	ENOG4105CBC	glutamate synthase
Thexy_0514	ENOG4105EYU	Glutamine amido-transferase
Thexy_0515	ENOG4107VHA	regulatoR
Thexy_0516	ENOG4105CAK	Cell division ATP-binding protein ftsE
Thexy_0517	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
Thexy_0518	ENOG4105DR5	peptidase
Thexy_0519	ENOG4105CN1	protease
Thexy_0521	ENOG4108N5B	2-phosphosulfolactate phosphatase
Thexy_0522	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Thexy_0524	ENOG4105HZM	Fha domain containing protein
Thexy_0526	ENOG4105CJN	penicillin-binding protein
Thexy_0529	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
Thexy_0531	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
Thexy_0532	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
Thexy_0534	ENOG4105DKQ	ROK family
Thexy_0535	ENOG4105CEY	Amp-dependent synthetase and ligase
Thexy_0538	ENOG4105CK5	oxidoreductase
Thexy_0540	ENOG4105WZ4	isomerase
Thexy_0541	ENOG4105D9R	oxidoreductase
Thexy_0542	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Thexy_0543	ENOG4105VCP	PTS System
Thexy_0544	ENOG4105CYT	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
Thexy_0548	ENOG4105CS2	ec 3.2.1.21
Thexy_0549	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
Thexy_0551	ENOG4105CNN	ABC, transporter
Thexy_0552	ENOG4105C2J	ABC transporter
Thexy_0553	ENOG4105CNN	ABC, transporter
Thexy_0554	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
Thexy_0555	ENOG4105EF1	ribulokinase
Thexy_0556	ENOG4105CR5	Class II aldolase adducin family protein
Thexy_0558	ENOG4105CMD	Transcriptional regulator, GntR family
Thexy_0559	ENOG4108MDK	Dehydrogenase
Thexy_0567	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
Thexy_0568	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
Thexy_0569	ENOG4105CMR	udp-glucose 4-epimerase
Thexy_0570	ENOG4105E2R	ROK family
Thexy_0576	ENOG4105CJ2	(LipO)protein
Thexy_0578	ENOG4105CJN	penicillin-binding protein
Thexy_0579	ENOG4105DQE	DNA ligase
Thexy_0580	ENOG4105FDF	Could be involved in DNA repair (By similarity)
Thexy_0586	ENOG4105EXC	Acyl-transferase
Thexy_0587	ENOG4105D5Q	Arginine ornithine antiporter
Thexy_0588	ENOG4105CVG	Homoserine O-transsuccinylase
Thexy_0590	ENOG41082MP	copper ion binding protein
Thexy_0592	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Thexy_0593	ENOG4105C98	muts2 protein
Thexy_0595	ENOG41080TK	Universal stress protein
Thexy_0601	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
Thexy_0602	ENOG4105DCG	PHP domain protein
Thexy_0604	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
Thexy_0608	ENOG4105C59	p-type ATPase
Thexy_0610	ENOG4105D4A	Cell wall formation (By similarity)
Thexy_0611	ENOG4105DCG	PHP domain protein
Thexy_0612	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Thexy_0619	ENOG4105C8Q	Methyl-accepting chemotaxis
Thexy_0620	ENOG4107FKK	extracellular solute-binding protein family 1
Thexy_0621	ENOG4105D56	permease protein
Thexy_0622	ENOG4105EG2	ABC transporter, permease
Thexy_0626	ENOG4108IUK	alpha amylase, catalytic
Thexy_0629	ENOG4105CIE	May be required for sporulation (By similarity)
Thexy_0630	ENOG4105KRI	phosphocarrier protein (HPr
Thexy_0632	ENOG4105C0B	DNA polymerase III (alpha subunit)
Thexy_0634	ENOG4105CTQ	phosphohexokinase
Thexy_0638	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Thexy_0645	ENOG4105EQR	Transposase IS116 IS110 IS902
Thexy_0649	ENOG4108K9K	Uncharacterised protein family (UPF0236)
Thexy_0650	ENOG4108HW3	(ABC) transporter
Thexy_0651	ENOG4105E5Q	amino acid AbC transporter
Thexy_0655	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Thexy_0657	ENOG4108Z3G	3H domain protein
Thexy_0659	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Thexy_0662	ENOG4107S1Q	Phosphatase
Thexy_0664	ENOG4108K9K	Uncharacterised protein family (UPF0236)
Thexy_0665	ENOG4105CD3	dihydroorotase
Thexy_0666	ENOG4105DBV	ornithine carbamoyltransferase
Thexy_0669	ENOG4105K8N	protein family UPF0079, ATPase
Thexy_0670	ENOG41072GX	Peptidase M22 Glycoprotease
Thexy_0671	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
Thexy_0672	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Thexy_0673	ENOG4105C5H	ABC transporter
Thexy_0674	ENOG4107R0U	MotA TolQ exbB proton channel
Thexy_0675	ENOG4105ER2	Ompa motb domain protein
Thexy_0677	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
Thexy_0680	ENOG4108UQV	Membrane
Thexy_0688	ENOG4108IV0	ABC, transporter
Thexy_0689	ENOG4105C0Z	ABC transporter
Thexy_0690	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Thexy_0691	ENOG4105C32	Amino acid ABC transporter (Permease)
Thexy_0694	ENOG4105C7J	ABC transporter, permease
Thexy_0695	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Thexy_0697	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
Thexy_0705	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Thexy_0706	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Thexy_0707	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Thexy_0708	ENOG4105C7N	Xanthine uracil vitamin C permease
Thexy_0709	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Thexy_0710	ENOG4105C8V	SAICAR synthetase
Thexy_0712	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Thexy_0713	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Thexy_0714	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Thexy_0715	ENOG4107QNG	Phosphoribosylglycinamide synthetase
Thexy_0716	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Thexy_0717	ENOG4105CH2	amidohydrolase
Thexy_0719	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
Thexy_0721	ENOG4105D01	(LipO)protein
Thexy_0722	ENOG4108UMI	ABC transporter, permease
Thexy_0723	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
Thexy_0724	ENOG4105ETD	TRANSCRIPTIONal
Thexy_0727	ENOG4105CK1	PTS System
Thexy_0728	ENOG4105VCP	PTS System
Thexy_0729	ENOG4105KGF	protein, YerC YecD
Thexy_0732	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Thexy_0733	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Thexy_0734	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Thexy_0735	ENOG4108J59	Extracellular solute-binding protein, family 5
Thexy_0736	ENOG4108J59	Extracellular solute-binding protein, family 5
Thexy_0737	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Thexy_0738	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Thexy_0740	ENOG4108JQ7	(ABC) transporter
Thexy_0741	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Thexy_0742	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
Thexy_0751	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
Thexy_0765	ENOG4107TVC	Glycosyl transferase, family 2
Thexy_0768	ENOG4105ECB	domain protein
Thexy_0771	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
Thexy_0773	ENOG4108TVJ	Nitroreductase
Thexy_0776	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Thexy_0778	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
Thexy_0782	ENOG4105EMS	pseudouridine synthase
Thexy_0792	ENOG4105KY8	Rubrerythrin
Thexy_0793	ENOG4105C5I	Dehydrogenase
Thexy_0794	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Thexy_0797	ENOG4105F3R	pts system mannose fructose sorbose family iid
Thexy_0798	ENOG4108IQ3	PTS system
Thexy_0799	ENOG4105C22	threonyL-tRNA synthetase
Thexy_0803	ENOG410688J	Ferredoxin
Thexy_0805	ENOG4105DAN	ATP-dependent protease
Thexy_0806	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
Thexy_0808	ENOG41073R8	VanW family
Thexy_0809	ENOG4105G5W	regulator Fur family
Thexy_0810	ENOG410667J	hydrolase
Thexy_0811	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
Thexy_0812	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Thexy_0815	ENOG4105BZA	Phosphoglycerate kinase
Thexy_0816	ENOG4105CP7	Triose-phosphate isomerase
Thexy_0817	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Thexy_0818	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Thexy_0820	ENOG4105VYW	UPF0251 protein
Thexy_0821	ENOG4105XZU	Preprotein translocase, subunit SecG
Thexy_0822	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
Thexy_0823	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Thexy_0824	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Thexy_0826	ENOG4105EGD	dinuclear metal center protein, YbgI family
Thexy_0827	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Thexy_0828	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
Thexy_0829	ENOG4105DG6	mannose-6-phosphate isomerase
Thexy_0834	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Thexy_0836	ENOG4108V0P	LemA family
Thexy_0838	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Thexy_0839	ENOG41083MR	nifu domain-containing protein
Thexy_0842	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Thexy_0843	ENOG4105VEQ	Cold shock protein
Thexy_0844	ENOG4107SC7	Inner membrane transporter yjeM
Thexy_0845	ENOG4105DC7	peptidase M24
Thexy_0846	ENOG4105HDK	L-asparaginase
Thexy_0847	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
Thexy_0849	ENOG4107SC7	Inner membrane transporter yjeM
Thexy_0854	ENOG4105XXY	Thioredoxin
Thexy_0855	ENOG4105CJR	Integral membrane protein (MviN
Thexy_0857	ENOG4107YEI	lmbE family
Thexy_0859	ENOG4105C08	Histidine kinase
Thexy_0860	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
Thexy_0861	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
Thexy_0862	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
Thexy_0863	ENOG4105BZU	Histidine kinase
Thexy_0864	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
Thexy_0865	ENOG4105BZU	Histidine kinase
Thexy_0866	ENOG4108ZJ4	polysaccharide deacetylase
Thexy_0870	ENOG4107YEI	lmbE family
Thexy_0871	ENOG4105DR5	peptidase
Thexy_0872	ENOG4105CNI	cell division protein FtsW
Thexy_0874	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Thexy_0875	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Thexy_0877	ENOG41060CR	
Thexy_0879	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Thexy_0885	ENOG4105DUM	transcriptional regulator, lysR family
Thexy_0886	ENOG41084XP	SirA-like domain-containing protein
Thexy_0887	ENOG4105CUC	YeeE YedE family protein
Thexy_0892	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
Thexy_0893	ENOG41076HS	cation diffusion facilitator family transporter
Thexy_0894	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Thexy_0895	ENOG4105G5W	regulator Fur family
Thexy_0898	ENOG4108JYZ	YitT family
Thexy_0900	ENOG4107QW8	radical SAM domain protein
Thexy_0902	ENOG4105D1F	ATP-binding protein
Thexy_0903	ENOG4107U53	septum site-determining protein minD
Thexy_0905	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
Thexy_0907	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Thexy_0908	ENOG4105BZU	Histidine kinase
Thexy_0910	ENOG4107RDB	Major Facilitator
Thexy_0912	ENOG4105C0H	protease
Thexy_0917	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Thexy_0918	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Thexy_0920	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
Thexy_0924	ENOG4105C1A	potassium transporter peripheral membrane
Thexy_0926	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Thexy_0927	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
Thexy_0931	ENOG4105CKB	glycosidase
Thexy_0932	ENOG4105CKB	glycosidase
Thexy_0933	ENOG4107FKK	extracellular solute-binding protein family 1
Thexy_0937	ENOG4105D7K	pfkb domain protein
Thexy_0938	ENOG4107Y7Q	pfkb domain protein
Thexy_0939	ENOG4107RK0	Sucrose phosphorylase
Thexy_0940	ENOG4105ETE	Transcriptional regulator (LacI family
Thexy_0942	ENOG4105CTS	PTS system mannitol-specific
Thexy_0943	ENOG4105ETD	TRANSCRIPTIONal
Thexy_0945	ENOG4107QZW	Altronate oxidoreductase
Thexy_0947	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Thexy_0950	ENOG41090UW	PTS System
Thexy_0951	ENOG4105DT3	PTS system, galactitol-specific IIc component
Thexy_0952	ENOG4108JQ1	Dehydrogenase
Thexy_0955	ENOG4105CXK	mandelate racemase muconate lactonizing
Thexy_0957	ENOG4108UHU	Aldolase
Thexy_0964	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
Thexy_0969	ENOG4108MK9	spermidine N(1)-acetyltransferase
Thexy_0971	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Thexy_0972	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Thexy_0976	ENOG4105C0D	helicase
Thexy_0981	ENOG4108HRK	Histidine kinase
Thexy_0982	ENOG4105DY9	regulatoR
Thexy_0985	ENOG4105DA5	(ABC) transporter
Thexy_0989	ENOG4105BZU	Histidine kinase
Thexy_0990	ENOG4108TVT	permease
Thexy_0991	ENOG4105CUB	amino acid
Thexy_0992	ENOG4107SCA	Formamidase (EC 3.5.1.49)
Thexy_0997	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Thexy_0999	ENOG4107QJZ	Glycosyl transferase, family 2
Thexy_1000	ENOG4105BZU	Histidine kinase
Thexy_1001	ENOG4108K9K	Uncharacterised protein family (UPF0236)
Thexy_1002	ENOG4105DWF	phosphomethylpyrimidine kinase
Thexy_1005	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Thexy_1006	ENOG4105F6S	Spore photoproduct lyase
Thexy_1009	ENOG4105BZU	Histidine kinase
Thexy_1012	ENOG4108YZA	Nitrogen regulatory protein pii
Thexy_1014	ENOG4105CAQ	asparagine synthetase
Thexy_1017	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Thexy_1020	ENOG4108UH6	UPF0754 membrane protein
Thexy_1021	ENOG4105C22	threonyL-tRNA synthetase
Thexy_1023	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Thexy_1024	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Thexy_1025	ENOG4105VJV	50s ribosomal protein L35
Thexy_1026	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Thexy_1027	ENOG4108RWN	rrna methyltransferase
Thexy_1028	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Thexy_1029	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Thexy_1031	ENOG4105CFP	Peptidase U32
Thexy_1032	ENOG4105C98	muts2 protein
Thexy_1035	ENOG4105WH1	Two component transcriptional regulator luxr family
Thexy_1036	ENOG4105DFM	M18 family aminopeptidase
Thexy_1037	ENOG4105K4I	Scp-like extracellular
Thexy_1041	ENOG4105EKQ	RNA-directed DNA polymerase
Thexy_1042	ENOG4107SBE	Glycosyl transferase (Group 1
Thexy_1043	ENOG4105VPX	protein, conserved in bacteria
Thexy_1045	ENOG4105Y5S	NADH ubiquinone oxidoreductase, 24 kD
Thexy_1050	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
Thexy_1051	ENOG4105C3G	gtp-binding protein
Thexy_1058	ENOG4105CJN	penicillin-binding protein
Thexy_1059	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Thexy_1060	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
Thexy_1061	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Thexy_1063	ENOG4105CNI	cell division protein FtsW
Thexy_1064	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Thexy_1065	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Thexy_1068	ENOG4105K67	small basic protein
Thexy_1069	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
Thexy_1070	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Thexy_1072	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Thexy_1073	ENOG4105E65	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Thexy_1076	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Thexy_1078	ENOG4105CVA	phosphate
Thexy_1079	ENOG4105C8U	phosphate abc transporter
Thexy_1080	ENOG4105E2Z	phosphate ABC transporter (Permease
Thexy_1081	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Thexy_1082	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
Thexy_1091	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
Thexy_1094	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
Thexy_1096	ENOG4108UVJ	appr-1-p processing domain protein
Thexy_1097	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Thexy_1099	ENOG41066FP	Small acid-soluble spore protein I
Thexy_1101	ENOG4105CNW	domain protein
Thexy_1103	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
Thexy_1104	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
Thexy_1106	ENOG4105DPN	Oligoendopeptidase f
Thexy_1108	ENOG4105EJQ	L-serine dehydratase
Thexy_1109	ENOG4105D49	3-dehydroquinate synthase
Thexy_1110	ENOG4105CQC	Prephenate dehydratase
Thexy_1111	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Thexy_1113	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Thexy_1114	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Thexy_1115	ENOG4105GR3	Histidine kinase
Thexy_1123	ENOG41066F8	ROK family
Thexy_1124	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
Thexy_1125	ENOG4107QIV	Cytochrome c biogenesis protein
Thexy_1126	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Thexy_1127	ENOG4105K63	Thioredoxin
Thexy_1128	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Thexy_1129	ENOG4105EB3	Histidine kinase
Thexy_1131	ENOG4105CXN	decarboxylase
Thexy_1132	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
Thexy_1133	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Thexy_1134	ENOG4107SWG	transcriptional regulator MERR family
Thexy_1136	ENOG4105NBF	ammecr1 domain protein
Thexy_1140	ENOG4105C02	permease
Thexy_1141	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Thexy_1142	ENOG4105VBH	UPF0297 protein
Thexy_1144	ENOG41068XD	UPF0473 protein
Thexy_1145	ENOG4105I3K	Ferric uptake regulator, Fur family
Thexy_1146	ENOG4105CN5	Metallo-Beta-Lactamase
Thexy_1147	ENOG41084CE	UPF0342 protein
Thexy_1149	ENOG4108VQJ	O-methyltransferase
Thexy_1150	ENOG4105CFP	Peptidase U32
Thexy_1151	ENOG4107XRG	penicillin-binding protein
Thexy_1152	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Thexy_1154	ENOG4105E2X	shikimate dehydrogenase
Thexy_1155	ENOG4107QHF	type ii secretion system protein e
Thexy_1156	ENOG4105CZX	twitching motility protein
Thexy_1169	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
Thexy_1170	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
Thexy_1171	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
Thexy_1172	ENOG4105DC7	peptidase M24
Thexy_1173	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Thexy_1175	ENOG4105CD2	stage iii sporulation protein aa
Thexy_1178	ENOG4105KQ4	Stage iii sporulation protein ad
Thexy_1180	ENOG410644B	Stage III sporulation protein af
Thexy_1183	ENOG4108ZSR	alkaline shock protein
Thexy_1184	ENOG4105M7K	Involved in the transcription termination process (By similarity)
Thexy_1185	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Thexy_1186	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Thexy_1187	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Thexy_1190	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Thexy_1191	ENOG4105DX0	Hemolysin A
Thexy_1192	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Thexy_1193	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
Thexy_1194	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Thexy_1195	ENOG4105S1Z	Stage IV sporulation protein B
Thexy_1196	ENOG4107QQR	Sporulation
Thexy_1202	ENOG4108YZ4	nudix hydrolase
Thexy_1204	ENOG4105MZ9	stage II sporulation protein m
Thexy_1205	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Thexy_1206	ENOG4105DZ1	carboxypeptidase
Thexy_1207	ENOG41082AN	stage II sporulation protein
Thexy_1208	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
Thexy_1209	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Thexy_1211	ENOG41084UG	Pfam:DUF1458
Thexy_1212	ENOG41090VF	Stage v sporulation protein ac
Thexy_1215	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Thexy_1216	ENOG4108Z4T	Peptidase M50
Thexy_1217	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
Thexy_1218	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
Thexy_1220	ENOG4105KBJ	sporulation protein ytfj
Thexy_1221	ENOG4105DZ1	carboxypeptidase
Thexy_1223	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Thexy_1224	ENOG4105FE9	pseudouridine synthase
Thexy_1226	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
Thexy_1227	ENOG4105CYW	agmatinase
Thexy_1228	ENOG4107QSA	Oxaloacetate decarboxylase
Thexy_1229	ENOG4106678	morphogenetic protein associated with SpoVID
Thexy_1231	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Thexy_1232	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
Thexy_1234	ENOG4105CBX	hi0933 family
Thexy_1236	ENOG4105CAT	Cytidine monophosphate kinase
Thexy_1238	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
Thexy_1239	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Thexy_1240	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
Thexy_1241	ENOG4105BZU	Histidine kinase
Thexy_1242	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Thexy_1244	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Thexy_1245	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Thexy_1246	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Thexy_1247	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
Thexy_1248	ENOG4105II7	pyrroline-5-carboxylate reductase
Thexy_1249	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Thexy_1250	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Thexy_1251	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Thexy_1252	ENOG4105CXI	aluminum resistance protein
Thexy_1253	ENOG4106F1P	AAA ATPase, central domain protein
Thexy_1254	ENOG4105C5S	asparaginyl-tRNA synthetase
Thexy_1257	ENOG4105DB7	PHP domain protein
Thexy_1258	ENOG4105MCT	stage V sporulation protein S
Thexy_1259	ENOG4105D48	metallophosphoesterase
Thexy_1260	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
Thexy_1261	ENOG4105EYH	Exonuclease
Thexy_1266	ENOG410902V	Modulates RecA activity (By similarity)
Thexy_1267	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Thexy_1269	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
Thexy_1270	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Thexy_1271	ENOG4105CNU	cell division protein FtsK
Thexy_1273	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
Thexy_1277	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
Thexy_1278	ENOG4105C1V	Peptidase, M16
Thexy_1280	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Thexy_1281	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Thexy_1282	ENOG4105DTN	riboflavin biosynthesis protein ribF
Thexy_1283	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Thexy_1284	ENOG4105SFS	phosphoesterase RecJ domain protein
Thexy_1285	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Thexy_1288	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
Thexy_1289	ENOG4105CHV	Transcription elongation factor NusA
Thexy_1290	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
Thexy_1291	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
Thexy_1293	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Thexy_1294	ENOG4105DZP	Membrane-associated zinc metalloprotease
Thexy_1295	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
Thexy_1296	ENOG4105KNE	Phosphatidate cytidylyltransferase
Thexy_1297	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Thexy_1299	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Thexy_1300	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Thexy_1301	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Thexy_1302	ENOG4105CE9	30S ribosomal protein S2
Thexy_1305	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Thexy_1306	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
Thexy_1308	ENOG4108V3W	Chemotaxis protein, CheW
Thexy_1309	ENOG4105CBS	Chea signal transduction histidine kinase
Thexy_1312	ENOG4105FZW	flagellar biosynthesis regulator FlhF
Thexy_1313	ENOG4105D7B	Flagellar biosynthesis protein flha
Thexy_1314	ENOG4105D00	flagellar biosynthetic protein flhB
Thexy_1315	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
Thexy_1316	ENOG4105VS8	Flagellar biosynthetic protein fliq
Thexy_1317	ENOG4105CN7	Flagellar biosynthetic protein FliP
Thexy_1319	ENOG4107YTP	response regulator receiver protein
Thexy_1320	ENOG4105DD5	Flagellar motor switch protein
Thexy_1321	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Thexy_1324	ENOG4105BZE	flagellar hook protein, FlgE
Thexy_1325	ENOG410822I	Flagellar hook capping protein
Thexy_1331	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Thexy_1332	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
Thexy_1333	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
Thexy_1334	ENOG4108ZC9	flagellar basal-body rod protein flgc
Thexy_1335	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
Thexy_1337	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
Thexy_1338	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
Thexy_1339	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Thexy_1341	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Thexy_1342	ENOG4105VFF	UPF0102 protein
Thexy_1343	ENOG4105C31	Tryptophanyl-tRNA synthetase
Thexy_1344	ENOG4105C0P	Mg chelatase subunit ChlI
Thexy_1346	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Thexy_1347	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Thexy_1348	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Thexy_1349	ENOG4105VB6	UPF0109 protein
Thexy_1350	ENOG4105K5M	30s ribosomal protein S16
Thexy_1352	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
Thexy_1353	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
Thexy_1355	ENOG4105MCT	stage V sporulation protein S
Thexy_1357	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Thexy_1358	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Thexy_1359	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Thexy_1360	ENOG4105CHR	reductase
Thexy_1361	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
Thexy_1362	ENOG4105EA8	2-Nitropropane dioxygenase
Thexy_1363	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Thexy_1364	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
Thexy_1365	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
Thexy_1366	ENOG41067VY	50S ribosomal protein L32
Thexy_1367	ENOG4105KNH	Nucleic acid-binding protein
Thexy_1368	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Thexy_1369	ENOG4108IJ2	phosphate acetyltransferase
Thexy_1371	ENOG4105H20	Sporulation integral membrane protein YlbJ
Thexy_1373	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Thexy_1374	ENOG4106H78	methyltransferase
Thexy_1376	ENOG4105EPR	degv family
Thexy_1377	ENOG4105CB5	ATP-dependent DNA helicase recG
Thexy_1378	ENOG4105DP4	dak2 domain fusion protein ylov
Thexy_1379	ENOG4108ZSR	alkaline shock protein
Thexy_1384	ENOG4105DJV	ribulose-phosphate 3-epimerase
Thexy_1385	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
Thexy_1386	ENOG4105D9P	serine threonine protein kinase
Thexy_1387	ENOG4108ZF3	Phosphatase
Thexy_1388	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Thexy_1389	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Thexy_1392	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Thexy_1393	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Thexy_1394	ENOG4105C25	Primosomal protein n'
Thexy_1395	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Thexy_1397	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Thexy_1399	ENOG4105DSJ	YicC domain protein
Thexy_1400	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
Thexy_1401	ENOG4105F23	Fibronectin-binding protein
Thexy_1402	ENOG41081HM	2'-5' rna ligase
Thexy_1405	ENOG4105DR4	Methyltransferase
Thexy_1406	ENOG4107XPQ	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Thexy_1407	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
Thexy_1408	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
Thexy_1410	ENOG4105CD3	dihydroorotase
Thexy_1411	ENOG4105CXT	aspartate transcarbamylase
Thexy_1412	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Thexy_1413	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
Thexy_1414	ENOG4105C5X	domain protein
Thexy_1416	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Thexy_1417	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Thexy_1418	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Thexy_1421	ENOG4107SBW	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Thexy_1422	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Thexy_1428	ENOG4107SVN	transposase
Thexy_1429	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Thexy_1430	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
Thexy_1431	ENOG4105JFG	SpoIID LytB domain protein
Thexy_1432	ENOG41061AI	Protein of unknown function (DUF2905)
Thexy_1433	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Thexy_1434	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Thexy_1435	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Thexy_1437	ENOG4108V3W	Chemotaxis protein, CheW
Thexy_1438	ENOG4105CDY	transcriptional regulatory protein
Thexy_1445	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
Thexy_1446	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
Thexy_1448	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Thexy_1452	ENOG4105D1H	recombination factor protein RarA
Thexy_1454	ENOG4105K63	Thioredoxin
Thexy_1455	ENOG4105VPX	protein, conserved in bacteria
Thexy_1456	ENOG4105CUZ	uba thif-type nad fad binding protein
Thexy_1458	ENOG4105CUT	histidyl-tRNA synthetase
Thexy_1459	ENOG4105C34	Pseudouridine synthase
Thexy_1460	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Thexy_1462	ENOG4105CV1	Transketolase (EC 2.2.1.1)
Thexy_1466	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Thexy_1470	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Thexy_1471	ENOG4108I0Q	anthranilate phosphoribosyltransferase
Thexy_1472	ENOG4105DDQ	anthranilate synthase
Thexy_1473	ENOG4105CRQ	synthase (Component I)
Thexy_1474	ENOG4108K9K	Uncharacterised protein family (UPF0236)
Thexy_1476	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
Thexy_1477	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Thexy_1480	ENOG4105DBK	s4 domain protein
Thexy_1482	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
Thexy_1483	ENOG4105DFA	alanine racemase domain protein
Thexy_1485	ENOG4105EP9	oxidoreductase
Thexy_1488	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
Thexy_1492	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Thexy_1493	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
Thexy_1494	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
Thexy_1498	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Thexy_1499	ENOG4107YR5	Diacylglycerol kinase
Thexy_1500	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
Thexy_1501	ENOG4105CTJ	Metal Dependent Phosphohydrolase
Thexy_1502	ENOG4105C9A	Phoh family
Thexy_1504	ENOG41068P3	sporulation protein YqfC
Thexy_1505	ENOG4105KTH	gatB Yqey
Thexy_1506	ENOG4105VCC	30S ribosomal protein S21
Thexy_1507	ENOG4107YU2	histidine triad (hIT) protein
Thexy_1508	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Thexy_1509	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
Thexy_1510	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Thexy_1511	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Thexy_1512	ENOG4105CFG	Acts as a chaperone (By similarity)
Thexy_1513	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Thexy_1515	ENOG4105CSA	Coproporphyrinogen iii oxidase
Thexy_1516	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Thexy_1518	ENOG4105CPK	Glycosyl transferase (Group 1
Thexy_1522	ENOG4105CEF	Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity)
Thexy_1524	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
Thexy_1526	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
Thexy_1527	ENOG4107XDQ	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Thexy_1528	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Thexy_1531	ENOG4105CJ1	ABC, transporter
Thexy_1536	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Thexy_1537	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Thexy_1538	ENOG41084EF	Ferredoxin
Thexy_1539	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
Thexy_1542	ENOG4105CPK	Glycosyl transferase (Group 1
Thexy_1543	ENOG4105BZ8	glutamate synthase
Thexy_1544	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
Thexy_1547	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Thexy_1548	ENOG4108W5N	phosphatidylglycerophosphatase a
Thexy_1549	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Thexy_1551	ENOG4105KQC	Competence protein
Thexy_1552	ENOG4105DZ1	carboxypeptidase
Thexy_1554	ENOG4105WWK	YheO domain protein
Thexy_1556	ENOG4108WF2	Metal Dependent Phosphohydrolase
Thexy_1557	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Thexy_1558	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Thexy_1560	ENOG4105K46	50S ribosomal protein l27
Thexy_1562	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Thexy_1563	ENOG4105C03	ribonuclease
Thexy_1567	ENOG4108K5P	(LipO)protein
Thexy_1568	ENOG4108Z5K	methylglyoxal synthase
Thexy_1569	ENOG4105CNI	cell division protein FtsW
Thexy_1570	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
Thexy_1571	ENOG4107QMS	site-determining protein
Thexy_1572	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
Thexy_1576	ENOG4105DFF	Rod shape-determining protein mreb
Thexy_1577	ENOG4105W5Q	DNA repair protein (RadC
Thexy_1578	ENOG4108Z03	MAF-like protein
Thexy_1580	ENOG4107QHI	-hydrogenase
Thexy_1581	ENOG4107QIZ	NADH dehydrogenase
Thexy_1583	ENOG4106AFQ	Histidine kinase
Thexy_1584	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
Thexy_1587	ENOG4108R3D	Electron transport complex
Thexy_1591	ENOG4105E4C	Lytic transglycosylase catalytic
Thexy_1592	ENOG4105CI3	gtp-binding protein typa
Thexy_1593	ENOG4107TT5	NLP P60 protein
Thexy_1596	ENOG4108VMM	UPF0756 membrane protein
Thexy_1597	ENOG4105E4C	Lytic transglycosylase catalytic
Thexy_1598	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Thexy_1601	ENOG4105EMN	RNA polymerase sigma factor
Thexy_1602	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
Thexy_1604	ENOG4105C85	amino acid
Thexy_1605	ENOG41067S9	phage shock protein C, PspC
Thexy_1606	ENOG4105VRS	hydrolase family 18
Thexy_1609	ENOG4108UIC	UPF0340 protein
Thexy_1610	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Thexy_1614	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Thexy_1616	ENOG4105DQU	oxidoreductase, subunit beta
Thexy_1617	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Thexy_1619	ENOG4105D9Q	decarboxylase (Beta subunit)
Thexy_1621	ENOG4108ZVT	methylmalonyl-coA epimerase
Thexy_1625	ENOG4105D82	Glutamate dehydrogenase
Thexy_1626	ENOG4107SC7	Inner membrane transporter yjeM
Thexy_1628	ENOG4105EPD	Oligopeptide transporter, Opt family
Thexy_1633	ENOG4105CKM	Branched-chain carboxylic acid kinase
Thexy_1635	ENOG4107RE7	phosphate butyryltransferase
Thexy_1642	ENOG4105DR5	peptidase
Thexy_1644	ENOG4105VRS	hydrolase family 18
Thexy_1647	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Thexy_1648	ENOG4105DYB	Isoaspartyl dipeptidase
Thexy_1652	ENOG4105BZU	Histidine kinase
Thexy_1656	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
Thexy_1657	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Thexy_1658	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Thexy_1659	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
Thexy_1662	ENOG4108ZJ4	polysaccharide deacetylase
Thexy_1663	ENOG4107URF	beta-phospho-glucomutase
Thexy_1667	ENOG4107FKK	extracellular solute-binding protein family 1
Thexy_1668	ENOG4105ETE	Transcriptional regulator (LacI family
Thexy_1669	ENOG4105DRS	transport system, permease
Thexy_1670	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
Thexy_1673	ENOG4105ETE	Transcriptional regulator (LacI family
Thexy_1676	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
Thexy_1680	ENOG4108K9K	Uncharacterised protein family (UPF0236)
Thexy_1682	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Thexy_1684	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Thexy_1685	ENOG4107ZYJ	bioY protein
Thexy_1687	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
Thexy_1689	ENOG4108UKJ	Cdp-alcohol phosphatidyltransferase
Thexy_1691	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
Thexy_1692	ENOG4108IFG	nitrite reductase, (NAD(P)H)
Thexy_1693	ENOG4105CNW	domain protein
Thexy_1696	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Thexy_1697	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Thexy_1701	ENOG4108K88	Membrane
Thexy_1702	ENOG4108KGH	TRANSCRIPTIONal
Thexy_1706	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
Thexy_1707	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
Thexy_1708	ENOG4107YJ4	chain length determinant protein
Thexy_1709	ENOG4105HTX	biosynthesis protein
Thexy_1712	ENOG4105DNE	Transposase
Thexy_1717	ENOG41069HH	4-oxalocrotonate tautomerase
Thexy_1725	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
Thexy_1726	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
Thexy_1727	ENOG4105XN3	extracellular solute-binding protein family 1
Thexy_1731	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
Thexy_1734	ENOG4108HRK	Histidine kinase
Thexy_1735	ENOG4105EQD	regulatoR
Thexy_1735	ENOG4105EQD	regulatoR
Thexy_1736	ENOG4105I82	acetyl xylan esterase
Thexy_1744	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
Thexy_1746	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
Thexy_1747	ENOG4107XBN	GntR Family Transcriptional Regulator
Thexy_1758	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
Thexy_1764	ENOG4107QRT	dEAD DEAH box helicase
Thexy_1769	ENOG4108K9K	Uncharacterised protein family (UPF0236)
Thexy_1773	ENOG4105DCI	Phosphohydrolase
Thexy_1776	ENOG4105C0D	helicase
Thexy_1783	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
Thexy_1796	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
Thexy_1802	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
Thexy_1812	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
Thexy_1813	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
Thexy_1815	ENOG4105D2X	ABC transporter substrate-binding protein
Thexy_1817	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
Thexy_1821	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Thexy_1822	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
Thexy_1823	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
Thexy_1824	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
Thexy_1825	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Thexy_1826	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
Thexy_1827	ENOG41082I9	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Thexy_1828	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
Thexy_1829	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Thexy_1830	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Thexy_1832	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Thexy_1833	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Thexy_1834	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Thexy_1836	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
Thexy_1838	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Thexy_1841	ENOG4105WEF	catalase
Thexy_1842	ENOG4105C3R	Methionine synthase
Thexy_1848	ENOG4108RCM	Nitroreductase
Thexy_1849	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
Thexy_1853	ENOG4105DVT	helicase
Thexy_1866	ENOG4105MQ3	flagellar protein FliS
Thexy_1867	ENOG4107RT6	flagellar hook-associated
Thexy_1875	ENOG4105MME	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family
Thexy_1876	ENOG4105D2T	synthase
Thexy_1878	ENOG4108DRC	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
Thexy_1879	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
Thexy_1880	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Thexy_1882	ENOG41090QV	Protein of unknown function DUF115
Thexy_1887	ENOG4105I03	Flagellin
Thexy_1888	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
Thexy_1889	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
Thexy_1891	ENOG4105DTJ	flagellar hook-associated protein
Thexy_1892	ENOG4105E1Q	flagellar hook-associated protein
Thexy_1896	ENOG4105MJ2	Competence protein
Thexy_1897	ENOG4105C7H	Helicase, RecD TraA family
Thexy_1899	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Thexy_1900	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Thexy_1901	ENOG4108RAC	Rubrerythrin
Thexy_1902	ENOG4105D3R	alkyl hydroperoxide reductase
Thexy_1905	ENOG4108ZDA	Sporulation protein YyaC
Thexy_1907	ENOG4105BZU	Histidine kinase
Thexy_1908	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Thexy_1909	ENOG4105CE4	GlcNAc 6-P deacetylase
Thexy_1910	ENOG4105ETE	Transcriptional regulator (LacI family
Thexy_1912	ENOG410667J	hydrolase
Thexy_1913	ENOG4108QG2	Membrane
Thexy_1919	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
Thexy_1921	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
Thexy_1923	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Thexy_1925	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Thexy_1926	ENOG4107SDT	Homocitrate synthase
Thexy_1931	ENOG4105C8Q	Methyl-accepting chemotaxis
Thexy_1933	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
Thexy_1935	ENOG4105FDP	GntR family transcriptional regulator
Thexy_1937	ENOG4105UIB	(ABC) transporter
Thexy_1938	ENOG4108JQ9	ABC transporter
Thexy_1939	ENOG4105DIH	basic membrane
Thexy_1941	ENOG4105CCS	Glutamate formiminotransferase
Thexy_1950	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Thexy_1955	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
Thexy_1956	ENOG4108YZT	Adenosylcobinamide kinase
Thexy_1957	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Thexy_1962	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Thexy_1963	ENOG4105E0A	ABC, transporter
Thexy_1964	ENOG4105EHG	Permease protein
Thexy_1965	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
Thexy_1974	ENOG4105CUB	amino acid
Thexy_1975	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
Thexy_1976	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Thexy_1978	ENOG4108ZB6	transcriptional regulator AsnC family
Thexy_1979	ENOG4105CHM	Aminotransferase
Thexy_1981	ENOG4105CE1	Ferrous iron transport protein b
Thexy_1983	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
Thexy_1984	ENOG4105I3K	Ferric uptake regulator, Fur family
Thexy_1985	ENOG4105DSE	periplasmic solute binding protein
Thexy_1986	ENOG4105FDK	ABC transporter
Thexy_1991	ENOG4105EJ9	Membrane
Thexy_1992	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Thexy_1993	ENOG4105CGH	5'-nucleotidase
Thexy_1995	ENOG4105VCP	PTS System
Thexy_1997	ENOG4105CK1	PTS System
Thexy_1999	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Thexy_2000	ENOG4105E5D	amino acid
Thexy_2002	ENOG4107GRR	phosphate transport regulator
Thexy_2003	ENOG4105CJ3	phosphate transporter
Thexy_2005	ENOG41089WN	small, acid-soluble spore protein tlp
Thexy_2006	ENOG4105C8T	Leucyl-tRNA synthetase
Thexy_2011	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Thexy_2012	ENOG4105BZU	Histidine kinase
Thexy_2013	ENOG4107SDU	Methyl-accepting chemotaxis
Thexy_2014	ENOG4105CBS	Chea signal transduction histidine kinase
Thexy_2015	ENOG4108V3W	Chemotaxis protein, CheW
Thexy_2016	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Thexy_2019	ENOG4105CHM	Aminotransferase
Thexy_2021	ENOG4108HWW	ABC transporter
Thexy_2023	ENOG4105DFW	ABC transporter
Thexy_2024	ENOG4105DFW	ABC transporter
Thexy_2025	ENOG4105EQD	regulatoR
Thexy_2026	ENOG4108HRK	Histidine kinase
Thexy_2028	ENOG4105NBU	tryptophan transport protein
Thexy_2035	ENOG4105CHR	reductase
Thexy_2036	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
Thexy_2037	ENOG4105ETE	Transcriptional regulator (LacI family
Thexy_2039	ENOG4105DEI	Mannitol dehydrogenase
Thexy_2040	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
Thexy_2041	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
Thexy_2042	ENOG4108JQ1	Dehydrogenase
Thexy_2046	ENOG4105UQX	Mate efflux family protein
Thexy_2048	ENOG4105CTX	dehydratase
Thexy_2049	ENOG4107QZW	Altronate oxidoreductase
Thexy_2051	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
Thexy_2052	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
Thexy_2054	ENOG4105F5H	Glycosyl Hydrolase Family 88
Thexy_2055	ENOG4107KJX	Transcriptional regulator
Thexy_2056	ENOG4105D2H	Uronic isomerase
Thexy_2057	ENOG4105VRS	hydrolase family 18
Thexy_2059	ENOG4105BZ8	glutamate synthase
Thexy_2060	ENOG4107T5J	pyridine nucleotide-disulfide oxidoreductase
Thexy_2066	ENOG4107ZTW	SNARE associated Golgi
Thexy_2067	ENOG4107QPH	glycogen) synthase
Thexy_2076	ENOG4105DSG	hydrolase family 43
Thexy_2079	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
Thexy_2080	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
Thexy_2083	ENOG4105DET	Rhamnulokinase
Thexy_2084	ENOG4105DKG	l-rhamnose isomerase
Thexy_2087	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
Thexy_2089	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
Thexy_2090	ENOG4105KNY	Microcompartments protein
Thexy_2091	ENOG4105KNY	Microcompartments protein
Thexy_2092	ENOG4105KNY	Microcompartments protein
Thexy_2093	ENOG4108X49	Ethanolamine utilization protein EutK
Thexy_2094	ENOG4105CPQ	Dehydrogenase
Thexy_2095	ENOG4108EKI	Dehydrogenase
Thexy_2098	ENOG41084PW	diol glycerol dehydratase reactivating factor large subunit
Thexy_2099	ENOG4108ZFT	Dehydratase small subunit
Thexy_2100	ENOG4105YCI	dehydratase medium subunit
Thexy_2103	ENOG4105E98	transcriptional regulator DeoR family
Thexy_2104	ENOG4105DNE	Transposase
Thexy_2106	ENOG4105QUH	Domain of unknown function (DUF2088)
Thexy_2107	ENOG4105CY0	Metallo-Beta-Lactamase
Thexy_2110	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Thexy_2114	ENOG4105UQX	Mate efflux family protein
Thexy_2115	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Thexy_2121	ENOG4105CIG	ABC transporter
Thexy_2123	ENOG4105MRR	Transcriptional regulator (By similarity)
Thexy_2124	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
Thexy_2125	ENOG4105G01	cobalamin (vitamin B12) biosynthesis CbiM protein
Thexy_2127	ENOG4108JJB	ABC transporter
Thexy_2128	ENOG4105EKQ	RNA-directed DNA polymerase
Thexy_2129	ENOG4107RGD	Major Facilitator superfamily
Thexy_2139	ENOG4106ETB	IIa component
Thexy_2142	ENOG4105D7K	pfkb domain protein
Thexy_2143	ENOG4108UHU	Aldolase
Thexy_2144	ENOG4108M60	Transcriptional regulator
Thexy_2146	ENOG4105CY0	Metallo-Beta-Lactamase
Thexy_2148	ENOG4105CMG	Carbohydrate kinase
Thexy_2150	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Thexy_2151	ENOG4105DUM	transcriptional regulator, lysR family
Thexy_2154	ENOG4108HQ0	Exopolysaccharide biosynthesis protein
Thexy_2157	ENOG4107QW4	alcohol dehydrogenase
Thexy_2159	ENOG4107TVC	Glycosyl transferase, family 2
Thexy_2160	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
Thexy_2161	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
Thexy_2165	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Thexy_2171	ENOG4105CGA	flagellar basal-body rod protein FlgG
Thexy_2174	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
Thexy_2184	ENOG4107QSE	Dipeptidase
Thexy_2185	ENOG4107SC7	Inner membrane transporter yjeM
Thexy_2187	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Thexy_2189	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
Thexy_2190	ENOG4105ESV	Glycosyl transferase, family 4
Thexy_2192	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
Thexy_2193	ENOG4108YZG	isomerase
Thexy_2194	ENOG4107WAU	Protein tyrosine phosphatase
Thexy_2195	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Thexy_2198	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Thexy_2199	ENOG4105CBJ	Metal-dependent enzyme
Thexy_2200	ENOG4107104	thymidine kinase
Thexy_2201	ENOG41082DI	50s ribosomal protein l31
Thexy_2202	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
Thexy_2205	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Thexy_2206	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Thexy_2208	ENOG4105BZ1	(ABC) transporter
Thexy_2209	ENOG4105BZ1	(ABC) transporter
Thexy_2213	ENOG4105CS2	ec 3.2.1.21
Thexy_2217	ENOG4105ETE	Transcriptional regulator (LacI family
Thexy_2225	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
Thexy_2227	ENOG4105DM4	PTS System
Thexy_2228	ENOG4105DM4	PTS System
Thexy_2229	ENOG4105DE4	1-phosphofructokinase
Thexy_2230	ENOG4105E98	transcriptional regulator DeoR family
Thexy_2237	ENOG4105CKK	Glycosyl transferase, family 2
Thexy_2238	ENOG4105EDW	glycosyl transferase, family 39
Thexy_2241	ENOG4105F3H	Histidine kinase
Thexy_2250	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Thexy_2251	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
Thexy_2257	ENOG4105C5R	Aminotransferase
Thexy_2258	ENOG4105BZW	Glycerate kinase
Thexy_2259	ENOG4105CN1	protease
Thexy_2260	ENOG4107SVN	transposase
Thexy_2261	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
Thexy_2262	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
Thexy_2263	ENOG4105D6E	homoserine dehydrogenase
Thexy_2264	ENOG41090I5	UPF0735 ACT domain-containing protein
Thexy_2266	ENOG4105Q2H	domain protein
Thexy_2267	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Thexy_2268	ENOG4105DQU	oxidoreductase, subunit beta
Thexy_2269	ENOG4105BZ1	(ABC) transporter
Thexy_2271	ENOG410834F	Transcriptional regulator
Thexy_2272	ENOG4105CMQ	Chloride channel
Thexy_2273	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Thexy_2274	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
Thexy_2285	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
Thexy_2292	ENOG4107YH3	SUF system FeS assembly protein, NifU family
Thexy_2294	ENOG4105DIW	FeS assembly protein SUFB
Thexy_2295	ENOG4105DIW	FeS assembly protein SUFB
Thexy_2306	ENOG4105VK3	rdd domain containing protein
Thexy_2316	ENOG4108EKI	Dehydrogenase
Thexy_2318	ENOG4105CPC	Aldo Keto reductase
Thexy_2322	ENOG4105CIZ	coA-substrate-specific enzyme activase
Thexy_2327	ENOG4105BZU	Histidine kinase
Thexy_2328	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
Thexy_2331	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Thexy_2335	ENOG4105BZU	Histidine kinase
Thexy_2336	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Thexy_2338	ENOG4108K5P	(LipO)protein
Thexy_2349	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Thexy_2350	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
Thexy_2367	ENOG4108JJ8	(ABC) transporter
Thexy_2375	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Thexy_2376	ENOG4105DZ0	fad dependent oxidoreductase
Thexy_2381	ENOG4105BZU	Histidine kinase
Thexy_2383	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
Thexy_2384	ENOG4105CJW	magnesium transporter
Thexy_2385	ENOG4105IJJ	transcriptional regulator, crp fnr family
Thexy_2386	ENOG4105CDU	Replicative dna helicase
Thexy_2387	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Thexy_2388	ENOG4105BZR	domain protein
Thexy_2391	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Thexy_2392	ENOG4108UUM	single-stranded DNA-binding protein
Thexy_2393	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
Thexy_2394	ENOG4105VDK	protein, conserved in bacteria
Thexy_2395	ENOG4105D8X	mechanosensitive ion channel
Thexy_2397	ENOG4108ZDA	Sporulation protein YyaC
Thexy_2400	ENOG4105CBD	Diacylglycerol kinase
Thexy_2403	ENOG4107QW8	radical SAM domain protein
Thexy_2404	ENOG4105FA0	parb-like partition protein
Thexy_2405	ENOG4107QJE	Chromosome Partitioning Protein
Thexy_2406	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
Thexy_2408	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Thexy_2409	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Thexy_2410	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Thexy_2411	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
Thexy_2412	ENOG4107R4E	Membrane
Thexy_2413	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
Thexy_2414	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
Thexy_2415	ENOG4105VG0	50S ribosomal protein l34