locus-tag	class	description
Tter_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Tter_0002	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Tter_0002	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Tter_0004	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Tter_0005	COG1024	Enoyl-CoA hydratase
Tter_0007	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Tter_0008	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Tter_0012	COG1028	Short-chain dehydrogenase reductase Sdr
Tter_0013	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Tter_0014	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Tter_0016	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Tter_0018	COG1940	carbohydrate kinase activity
Tter_0021	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Tter_0025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Tter_0028	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
Tter_0031	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Tter_0032	COG0531	amino acid
Tter_0035	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Tter_0036	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
Tter_0037	COG0175	sulfate reduction
Tter_0039	COG2046	Belongs to the sulfate adenylyltransferase family
Tter_0040	COG0730	response to heat
Tter_0041	COG2855	membrane
Tter_0043	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Tter_0044	COG0456	acetyltransferase
Tter_0045	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Tter_0046	COG0802	atpase or kinase
Tter_0048	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Tter_0051	COG0187	DNA topoisomerase II activity
Tter_0052	COG0416	fatty acid biosynthetic process
Tter_0053	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Tter_0054	COG1546	Belongs to the CinA family
Tter_0054	COG1058	Belongs to the CinA family
Tter_0055	COG0148	phosphopyruvate hydratase activity
Tter_0058	COG0154	amidase activity
Tter_0059	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Tter_0060	COG0772	Belongs to the SEDS family
Tter_0061	COG1077	Cell shape determining protein MreB Mrl
Tter_0062	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Tter_0063	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Tter_0064	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Tter_0065	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Tter_0066	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Tter_0068	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Tter_0069	COG0356	it plays a direct role in the translocation of protons across the membrane
Tter_0071	COG0504	CTP synthase activity
Tter_0072	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Tter_0073	COG2137	regulation of response to DNA damage stimulus
Tter_0074	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Tter_0078	COG1252	NADH dehydrogenase
Tter_0079	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Tter_0080	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Tter_0081	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Tter_0082	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
Tter_0084	COG0717	Belongs to the dCTP deaminase family
Tter_0086	COG0632	four-way junction helicase activity
Tter_0087	COG3191	aminopeptidase activity
Tter_0089	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Tter_0090	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Tter_0091	COG0022	dehydrogenase e1 component
Tter_0091	COG0508	dehydrogenase complex catalyzes the overall conversion of
Tter_0092	COG0508	dehydrogenase complex catalyzes the overall conversion of
Tter_0093	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Tter_0094	COG0022	dehydrogenase e1 component
Tter_0095	COG0508	dehydrogenase complex catalyzes the overall conversion of
Tter_0096	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Tter_0097	COG0321	lipoyl(octanoyl) transferase activity
Tter_0099	COG2379	hydroxypyruvate reductase
Tter_0103	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Tter_0103	COG0758	DNA mediated transformation
Tter_0106	COG0287	Prephenate dehydrogenase
Tter_0107	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Tter_0108	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Tter_0109	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Tter_0113	COG1573	uracil-dna glycosylase
Tter_0114	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Tter_0115	COG0596	Alpha beta hydrolase
Tter_0115	COG0508	dehydrogenase complex catalyzes the overall conversion of
Tter_0116	COG3291	Pkd domain containing protein
Tter_0116	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Tter_0118	COG0083	homoserine kinase activity
Tter_0119	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Tter_0121	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Tter_0122	COG1764	response to oxidative stress
Tter_0124	COG0395	ABC-type sugar transport system, permease component
Tter_0125	COG1175	transmembrane transport
Tter_0127	COG1063	alcohol dehydrogenase
Tter_0129	COG0306	phosphate transporter
Tter_0130	COG1470	cell adhesion involved in biofilm formation
Tter_0133	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Tter_0135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Tter_0135	COG0321	lipoyl(octanoyl) transferase activity
Tter_0136	COG1506	peptidase
Tter_0136	COG0823	Involved in the tonB-independent uptake of proteins
Tter_0137	COG1486	melibiose metabolic process
Tter_0139	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Tter_0140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Tter_0143	COG3835	regulator
Tter_0144	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Tter_0145	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Tter_0146	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Tter_0146	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Tter_0147	COG0859	PFAM glycosyl transferase family 9
Tter_0152	COG4221	oxidoreductase activity
Tter_0154	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Tter_0157	COG1028	Short-chain dehydrogenase reductase Sdr
Tter_0160	COG0277	FAD linked oxidase domain protein
Tter_0161	COG0277	FAD linked oxidase domain protein
Tter_0162	COG0247	lactate metabolic process
Tter_0163	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Tter_0164	COG1940	carbohydrate kinase activity
Tter_0165	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Tter_0170	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Tter_0172	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Tter_0173	COG0745	RESPONSE REGULATOR receiver
Tter_0174	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
Tter_0175	COG0693	protein deglycase activity
Tter_0176	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Tter_0176	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Tter_0177	COG0612	Peptidase, M16
Tter_0178	COG0612	Peptidase, M16
Tter_0184	COG1175	transmembrane transport
Tter_0185	COG0395	ABC-type sugar transport system, permease component
Tter_0186	COG0028	Belongs to the TPP enzyme family
Tter_0187	COG0440	acetolactate synthase activity
Tter_0188	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Tter_0190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Tter_0191	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Tter_0192	COG0473	3-isopropylmalate dehydrogenase activity
Tter_0193	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Tter_0194	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Tter_0195	COG0066	3-isopropylmalate dehydratase activity
Tter_0196	COG0129	dihydroxy-acid dehydratase activity
Tter_0198	COG2323	membrane
Tter_0201	COG3458	cephalosporin-C deacetylase activity
Tter_0204	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Tter_0206	COG0395	ABC-type sugar transport system, permease component
Tter_0212	COG1012	belongs to the aldehyde dehydrogenase family
Tter_0216	COG1486	melibiose metabolic process
Tter_0220	COG1216	Glycosyl transferase, family 2
Tter_0222	COG1994	Peptidase M50
Tter_0222	COG0517	IMP dehydrogenase activity
Tter_0223	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Tter_0227	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Tter_0230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Tter_0230	COG1116	anion transmembrane transporter activity
Tter_0231	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Tter_0234	COG1295	ribonuclease BN
Tter_0235	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Tter_0236	COG4555	ABC transporter
Tter_0238	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Tter_0240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Tter_0241	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Tter_0244	COG1640	4-alpha-glucanotransferase
Tter_0246	COG1595	DNA-templated transcription, initiation
Tter_0247	COG3794	PFAM blue (type 1) copper domain protein
Tter_0248	COG4946	Tricorn protease homolog
Tter_0248	COG1506	peptidase
Tter_0248	COG0823	Involved in the tonB-independent uptake of proteins
Tter_0253	COG2890	protein-(glutamine-N5) methyltransferase activity
Tter_0255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Tter_0258	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Tter_0258	COG4651	solute:proton antiporter activity
Tter_0259	COG0517	IMP dehydrogenase activity
Tter_0259	COG1994	Peptidase M50
Tter_0263	COG1175	transmembrane transport
Tter_0264	COG0395	ABC-type sugar transport system, permease component
Tter_0266	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Tter_0267	COG4948	Mandelate Racemase Muconate Lactonizing
Tter_0268	COG1028	Short-chain dehydrogenase reductase Sdr
Tter_0270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Tter_0273	COG1082	Xylose isomerase domain protein TIM barrel
Tter_0274	COG0673	inositol 2-dehydrogenase activity
Tter_0275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Tter_0277	COG1136	(ABC) transporter
Tter_0278	COG1136	(ABC) transporter
Tter_0282	COG1132	(ABC) transporter
Tter_0283	COG1132	(ABC) transporter
Tter_0285	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Tter_0286	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Tter_0287	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Tter_0288	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Tter_0289	COG0045	succinate-CoA ligase (ADP-forming) activity
Tter_0290	COG5002	protein histidine kinase activity
Tter_0291	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Tter_0295	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Tter_0306	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Tter_0308	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Tter_0309	COG0747	negative chemotaxis
Tter_0311	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Tter_0312	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Tter_0313	COG0137	argininosuccinate synthase activity
Tter_0314	COG0165	Argininosuccinate lyase
Tter_0316	COG0189	ligase activity
Tter_0317	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Tter_0318	COG0189	ligase activity
Tter_0319	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Tter_0320	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Tter_0321	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Tter_0322	COG0673	inositol 2-dehydrogenase activity
Tter_0324	COG0137	argininosuccinate synthase activity
Tter_0325	COG0167	dihydroorotate dehydrogenase activity
Tter_0327	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Tter_0330	COG0366	Alpha amylase catalytic
Tter_0331	COG0366	Alpha amylase catalytic
Tter_0332	COG0508	dehydrogenase complex catalyzes the overall conversion of
Tter_0333	COG0567	Dehydrogenase, E1 component
Tter_0334	COG0674	pyruvate-flavodoxin oxidoreductase activity
Tter_0334	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Tter_0335	COG1013	pyruvate-flavodoxin oxidoreductase activity
Tter_0342	COG1595	DNA-templated transcription, initiation
Tter_0345	COG2720	vancomycin resistance protein
Tter_0347	COG0735	belongs to the Fur family
Tter_0348	COG1321	iron dependent repressor
Tter_0350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Tter_0351	COG2362	D-Aminopeptidase
Tter_0352	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Tter_0353	COG1446	asparaginase
Tter_0354	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Tter_0355	COG2189	Belongs to the N(4) N(6)-methyltransferase family
Tter_0356	COG0406	alpha-ribazole phosphatase activity
Tter_0362	COG1960	acyl-CoA dehydrogenase activity
Tter_0363	COG0183	Belongs to the thiolase family
Tter_0364	COG1960	acyl-CoA dehydrogenase activity
Tter_0365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Tter_0369	COG1122	ATPase activity
Tter_0370	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Tter_0372	COG0071	Belongs to the small heat shock protein (HSP20) family
Tter_0375	COG0788	formyltetrahydrofolate deformylase activity
Tter_0377	COG0697	spore germination
Tter_0383	COG0071	Belongs to the small heat shock protein (HSP20) family
Tter_0384	COG2259	Doxx family
Tter_0393	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Tter_0394	COG1260	myo-inositol-1-phosphate synthase
Tter_0397	COG1653	transport
Tter_0401	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Tter_0402	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Tter_0403	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Tter_0409	COG0277	FAD linked oxidase domain protein
Tter_0410	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Tter_0411	COG1070	Carbohydrate kinase
Tter_0412	COG0363	glucosamine-6-phosphate deaminase activity
Tter_0413	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Tter_0415	COG3959	Transketolase, thiamine diphosphate binding domain
Tter_0416	COG1070	Carbohydrate kinase
Tter_0418	COG4166	transmembrane transport
Tter_0419	COG0601	transmembrane transport
Tter_0420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Tter_0422	COG0114	fumarate hydratase activity
Tter_0423	COG0616	signal peptide processing
Tter_0426	COG1609	Transcriptional regulator
Tter_0428	COG1175	transmembrane transport
Tter_0429	COG0395	ABC-type sugar transport system, permease component
Tter_0430	COG3250	beta-galactosidase activity
Tter_0435	COG0791	NLP P60 protein
Tter_0436	COG1490	D-aminoacyl-tRNA deacylase activity
Tter_0438	COG0018	arginyl-trna synthetase
Tter_0439	COG2235	arginine
Tter_0440	COG3119	arylsulfatase activity
Tter_0442	COG5001	Diguanylate cyclase
Tter_0445	COG1472	Belongs to the glycosyl hydrolase 3 family
Tter_0446	COG0673	inositol 2-dehydrogenase activity
Tter_0451	COG1028	Short-chain dehydrogenase reductase Sdr
Tter_0452	COG1028	Short-chain dehydrogenase reductase Sdr
Tter_0453	COG0488	(ABC) transporter
Tter_0455	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Tter_0456	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Tter_0458	COG0154	amidase activity
Tter_0459	COG1595	DNA-templated transcription, initiation
Tter_0461	COG1131	(ABC) transporter
Tter_0464	COG0405	Gamma-glutamyltransferase
Tter_0465	COG1482	cell wall glycoprotein biosynthetic process
Tter_0466	COG0442	prolyl-tRNA aminoacylation
Tter_0469	COG1285	pathogenesis
Tter_0471	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Tter_0472	COG1213	nucleotidyl transferase
Tter_0472	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Tter_0474	COG0067	glutamate synthase
Tter_0474	COG0070	glutamate synthase
Tter_0474	COG0069	glutamate synthase activity
Tter_0478	COG4581	dead DEAH box helicase
Tter_0482	COG1131	(ABC) transporter
Tter_0485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Tter_0486	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
Tter_0486	COG0662	Cupin 2, conserved barrel domain protein
Tter_0487	COG1216	Glycosyl transferase, family 2
Tter_0488	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Tter_0489	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Tter_0490	COG0254	rRNA binding
Tter_0491	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Tter_0494	COG0714	Associated with various cellular activities
Tter_0495	COG0768	penicillin binding
Tter_0500	COG0516	GMP reductase activity
Tter_0500	COG0517	IMP dehydrogenase activity
Tter_0501	COG1475	DNA binding
Tter_0502	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Tter_0503	COG2226	methyltransferase
Tter_0506	COG0395	ABC-type sugar transport system, permease component
Tter_0507	COG1175	transmembrane transport
Tter_0509	COG2096	Adenosyltransferase
Tter_0514	COG1999	signal sequence binding
Tter_0528	COG2194	sulfuric ester hydrolase activity
Tter_0530	COG2909	trisaccharide binding
Tter_0532	COG2132	Multicopper oxidase
Tter_0534	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Tter_0536	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Tter_0539	COG0071	Belongs to the small heat shock protein (HSP20) family
Tter_0540	COG1234	tRNA 3'-trailer cleavage
Tter_0552	COG2378	regulation of single-species biofilm formation
Tter_0554	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Tter_0555	COG1085	galactose-1-phosphate uridylyltransferase
Tter_0558	COG0673	inositol 2-dehydrogenase activity
Tter_0563	COG0459	protein refolding
Tter_0564	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Tter_0565	COG2235	arginine
Tter_0566	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
Tter_0568	COG0247	lactate metabolic process
Tter_0570	COG1316	TRANSCRIPTIONal
Tter_0572	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Tter_0573	COG3584	3D domain protein
Tter_0573	COG1388	LysM domain
Tter_0577	COG3103	Sh3 type 3 domain protein
Tter_0577	COG1388	LysM domain
Tter_0577	COG0791	NLP P60 protein
Tter_0579	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Tter_0580	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Tter_0580	COG1648	precorrin-2 dehydrogenase activity
Tter_0581	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Tter_0586	COG0559	Belongs to the binding-protein-dependent transport system permease family
Tter_0588	COG0411	ABC transporter
Tter_0594	COG0488	(ABC) transporter
Tter_0596	COG0202	RNA polymerase activity
Tter_0597	COG2252	PERMEase
Tter_0608	COG3058	Necessary for formate dehydrogenase activity
Tter_0611	COG0437	4 iron, 4 sulfur cluster binding
Tter_0615	COG1993	acr, cog1993
Tter_0627	COG0569	domain protein
Tter_0628	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Tter_0632	COG1160	GTP binding
Tter_0639	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Tter_0644	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Tter_0645	COG0352	thiamine-phosphate diphosphorylase activity
Tter_0646	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Tter_0647	COG0351	phosphomethylpyrimidine kinase
Tter_0647	COG0352	thiamine-phosphate diphosphorylase activity
Tter_0648	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
Tter_0649	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Tter_0652	COG0673	inositol 2-dehydrogenase activity
Tter_0653	COG1129	ABC transporter
Tter_0654	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Tter_0655	COG2086	electron transfer activity
Tter_0658	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Tter_0659	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Tter_0661	COG0131	Imidazoleglycerol-phosphate dehydratase
Tter_0662	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Tter_0663	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Tter_0664	COG0107	imidazoleglycerol-phosphate synthase activity
Tter_0665	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Tter_0666	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Tter_0668	COG2514	catechol 2,3-dioxygenase activity
Tter_0669	COG1404	Belongs to the peptidase S8 family
Tter_0670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tter_0671	COG2226	methyltransferase
Tter_0672	COG0824	Thioesterase
Tter_0673	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Tter_0675	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Tter_0676	COG0095	Lipoate-protein ligase
Tter_0677	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Tter_0678	COG0859	PFAM glycosyl transferase family 9
Tter_0679	COG0205	6-phosphofructokinase activity
Tter_0682	COG3870	Protein conserved in bacteria
Tter_0683	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Tter_0684	COG3854	ATPases associated with a variety of cellular activities
Tter_0686	COG0521	Mo-molybdopterin cofactor biosynthetic process
Tter_0688	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Tter_0689	COG1187	pseudouridine synthase activity
Tter_0690	COG1686	Belongs to the peptidase S11 family
Tter_0691	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Tter_0693	COG0424	maF-like protein
Tter_0694	COG3404	Formiminotransferase-cyclodeaminase
Tter_0695	COG1131	(ABC) transporter
Tter_0696	COG0419	ATPase involved in DNA repair
Tter_0698	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Tter_0699	COG4166	transmembrane transport
Tter_0700	COG0601	transmembrane transport
Tter_0701	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Tter_0703	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Tter_0706	COG0336	Belongs to the RNA methyltransferase TrmD family
Tter_0707	COG0728	peptidoglycan biosynthetic process
Tter_0708	COG0085	RNA polymerase activity
Tter_0709	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Tter_0710	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Tter_0711	COG0049	tRNA binding
Tter_0712	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Tter_0713	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Tter_0714	COG0051	transcription antitermination factor activity, RNA binding
Tter_0715	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Tter_0716	COG0088	Forms part of the polypeptide exit tunnel
Tter_0717	COG0089	rRNA binding
Tter_0718	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Tter_0720	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Tter_0721	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Tter_0722	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Tter_0723	COG0255	Belongs to the universal ribosomal protein uL29 family
Tter_0724	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Tter_0725	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Tter_0726	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Tter_0727	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Tter_0728	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Tter_0729	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Tter_0730	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Tter_0731	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Tter_0732	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Tter_0734	COG0200	Binds to the 23S rRNA
Tter_0736	COG0563	adenylate kinase activity
Tter_0738	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Tter_0739	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Tter_0740	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Tter_0741	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Tter_0742	COG0202	RNA polymerase activity
Tter_0743	COG0203	ribosomal protein L17
Tter_0744	COG0101	tRNA pseudouridine synthase activity
Tter_0745	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Tter_0750	COG0123	including yeast histone deacetylase and acetoin utilization protein
Tter_0751	COG0477	Major facilitator Superfamily
Tter_0752	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Tter_0756	COG1595	DNA-templated transcription, initiation
Tter_0757	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Tter_0758	COG1028	Short-chain dehydrogenase reductase Sdr
Tter_0760	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Tter_0761	COG1234	tRNA 3'-trailer cleavage
Tter_0762	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Tter_0763	COG2814	Major facilitator Superfamily
Tter_0765	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Tter_0765	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Tter_0767	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Tter_0768	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Tter_0769	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Tter_0770	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Tter_0771	COG0072	phenylalanine-tRNA ligase activity
Tter_0771	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Tter_0772	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Tter_0775	COG0322	excinuclease ABC activity
Tter_0776	COG0552	protein localization to endoplasmic reticulum
Tter_0777	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Tter_0778	COG0360	Binds together with S18 to 16S ribosomal RNA
Tter_0779	COG0629	single-stranded DNA binding
Tter_0780	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Tter_0781	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Tter_0782	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Tter_0784	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Tter_0785	COG1053	succinate dehydrogenase
Tter_0787	COG2009	succinate dehydrogenase
Tter_0788	COG0473	3-isopropylmalate dehydrogenase activity
Tter_0789	COG0745	RESPONSE REGULATOR receiver
Tter_0790	COG2204	response regulator
Tter_0792	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Tter_0793	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Tter_0794	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Tter_0795	COG1573	uracil-dna glycosylase
Tter_0796	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Tter_0797	COG1674	ftsk spoiiie
Tter_0800	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Tter_0801	COG1381	Involved in DNA repair and RecF pathway recombination
Tter_0804	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Tter_0805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Tter_0807	COG0569	domain protein
Tter_0811	COG0653	protein targeting
Tter_0812	COG1921	L-seryl-tRNASec selenium transferase activity
Tter_0813	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tter_0817	COG0444	Belongs to the ABC transporter superfamily
Tter_0818	COG4608	Belongs to the ABC transporter superfamily
Tter_0819	COG1994	Peptidase M50
Tter_0821	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Tter_0822	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Tter_0823	COG4948	Mandelate Racemase Muconate Lactonizing
Tter_0826	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Tter_0828	COG1609	Transcriptional regulator
Tter_0830	COG1175	transmembrane transport
Tter_0831	COG0395	ABC-type sugar transport system, permease component
Tter_0832	COG1063	alcohol dehydrogenase
Tter_0833	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Tter_0834	COG0019	diaminopimelate decarboxylase activity
Tter_0836	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Tter_0838	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Tter_0842	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Tter_0844	COG0527	aspartate kinase activity
Tter_0844	COG0460	homoserine dehydrogenase
Tter_0846	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Tter_0858	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Tter_0861	COG0437	4 iron, 4 sulfur cluster binding
Tter_0864	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
Tter_0868	COG0297	glycogen (starch) synthase activity
Tter_0869	COG0822	iron-sulfur transferase activity
Tter_0870	COG1012	belongs to the aldehyde dehydrogenase family
Tter_0871	COG1515	deoxyribonuclease V activity
Tter_0872	COG4974	Belongs to the 'phage' integrase family
Tter_0876	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Tter_0877	COG1605	Chorismate mutase
Tter_0877	COG0077	Prephenate dehydratase
Tter_0881	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Tter_0882	COG0310	cobalt ion transport
Tter_0883	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Tter_0884	COG1122	ATPase activity
Tter_0886	COG0179	Fumarylacetoacetate (FAA) hydrolase
Tter_0889	COG0730	response to heat
Tter_0891	COG3214	Protein conserved in bacteria
Tter_0899	COG4608	Belongs to the ABC transporter superfamily
Tter_0902	COG1279	arginine transmembrane transporter activity
Tter_0903	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Tter_0904	COG0765	amino acid transport
Tter_0906	COG0606	chelatase, subunit chli
Tter_0907	COG0196	riboflavin kinase activity
Tter_0908	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Tter_0909	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Tter_0910	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Tter_0912	COG0195	Participates in both transcription termination and antitermination
Tter_0914	COG0126	phosphoglycerate kinase activity
Tter_0915	COG0149	triose-phosphate isomerase activity
Tter_0917	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Tter_0920	COG0571	ribonuclease III activity
Tter_0922	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Tter_0923	COG0582	viral genome integration into host DNA
Tter_0925	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Tter_0928	COG2255	four-way junction helicase activity
Tter_0930	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Tter_0931	COG0343	queuine tRNA-ribosyltransferase activity
Tter_0932	COG0736	holo-[acyl-carrier-protein] synthase activity
Tter_0933	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Tter_0933	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Tter_0934	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Tter_0939	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Tter_0940	COG1475	DNA binding
Tter_0941	COG1192	Involved in chromosome partitioning
Tter_0942	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Tter_0943	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Tter_0947	COG0268	Binds directly to 16S ribosomal RNA
Tter_0948	COG0481	GTPase activity
Tter_0949	COG3956	TIGRFAM MazG family protein
Tter_0951	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Tter_0955	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Tter_0956	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Tter_0958	COG0217	transcriptional regulatory protein
Tter_0959	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Tter_0959	COG0519	Catalyzes the synthesis of GMP from XMP
Tter_0960	COG0151	Belongs to the GarS family
Tter_0963	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Tter_0966	COG1028	Short-chain dehydrogenase reductase Sdr
Tter_0968	COG0489	protein tyrosine kinase activity
Tter_0969	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Tter_0972	COG2264	protein methyltransferase activity
Tter_0973	COG3842	ATPase activity
Tter_0974	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Tter_0976	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Tter_0979	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Tter_0981	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tter_0982	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Tter_0983	COG0671	phosphoesterase, PA-phosphatase related
Tter_0984	COG3118	belongs to the thioredoxin family
Tter_0985	COG1832	CoA-binding protein
Tter_0989	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Tter_0991	COG2815	serine threonine protein kinase
Tter_0991	COG0515	serine threonine protein kinase
Tter_0992	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Tter_0993	COG0592	DNA-directed DNA polymerase activity
Tter_0995	COG3359	exonuclease
Tter_0997	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Tter_0998	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Tter_1000	COG0484	heat shock protein binding
Tter_1002	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Tter_1003	COG1199	ATP-dependent helicase activity
Tter_1004	COG0515	serine threonine protein kinase
Tter_1004	COG2815	serine threonine protein kinase
Tter_1007	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Tter_1008	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Tter_1009	COG0495	leucyl-tRNA aminoacylation
Tter_1010	COG0084	hydrolase, TatD family'
Tter_1011	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Tter_1012	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Tter_1013	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Tter_1014	COG0047	phosphoribosylformylglycinamidine synthase activity
Tter_1015	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Tter_1016	COG0745	RESPONSE REGULATOR receiver
Tter_1020	COG2894	cell division
Tter_1028	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Tter_1029	COG2205	protein histidine kinase activity
Tter_1030	COG0745	RESPONSE REGULATOR receiver
Tter_1031	COG2205	protein histidine kinase activity
Tter_1031	COG2202	Pas domain
Tter_1032	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Tter_1033	COG0482	sulfurtransferase activity
Tter_1039	COG1968	undecaprenyl-diphosphatase activity
Tter_1040	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Tter_1042	COG0438	transferase activity, transferring glycosyl groups
Tter_1045	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Tter_1052	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Tter_1053	COG0586	Pfam SNARE associated Golgi protein
Tter_1055	COG0537	adenosine 5'-monophosphoramidase activity
Tter_1056	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Tter_1057	COG1610	YqeY-like protein
Tter_1058	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Tter_1059	COG1058	Belongs to the CinA family
Tter_1059	COG1546	Belongs to the CinA family
Tter_1061	COG1051	belongs to the nudix hydrolase family
Tter_1064	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Tter_1065	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Tter_1067	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Tter_1068	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Tter_1071	COG0745	RESPONSE REGULATOR receiver
Tter_1072	COG5002	protein histidine kinase activity
Tter_1073	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Tter_1073	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Tter_1075	COG1796	DNA polymerase
Tter_1075	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Tter_1076	COG0714	Associated with various cellular activities
Tter_1078	COG1305	Transglutaminase-like
Tter_1082	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
Tter_1083	COG1846	Transcriptional regulator
Tter_1088	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Tter_1090	COG1950	PFAM Membrane protein of
Tter_1093	COG3833	ABC-type maltose transport systems, permease component
Tter_1094	COG1175	transmembrane transport
Tter_1095	COG1653	transport
Tter_1097	COG5002	protein histidine kinase activity
Tter_1097	COG3850	Histidine kinase
Tter_1100	COG3401	FG-GAP repeat protein
Tter_1101	COG1653	transport
Tter_1102	COG0395	ABC-type sugar transport system, permease component
Tter_1103	COG4209	transmembrane transport
Tter_1104	COG1802	Transcriptional regulator
Tter_1105	COG0673	inositol 2-dehydrogenase activity
Tter_1108	COG4585	Histidine kinase
Tter_1109	COG2197	response regulator
Tter_1110	COG1271	oxidase subunit
Tter_1111	COG1294	oxidase, subunit
Tter_1112	COG1082	Xylose isomerase domain protein TIM barrel
Tter_1114	COG3584	3D domain protein
Tter_1125	COG2197	response regulator
Tter_1130	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Tter_1131	COG5002	protein histidine kinase activity
Tter_1132	COG2197	response regulator
Tter_1134	COG5002	protein histidine kinase activity
Tter_1135	COG0745	RESPONSE REGULATOR receiver
Tter_1143	COG3291	Pkd domain containing protein
Tter_1143	COG4412	M6 family metalloprotease domain protein
Tter_1161	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Tter_1162	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
Tter_1166	COG1132	(ABC) transporter
Tter_1169	COG0598	Magnesium transport protein CorA
Tter_1170	COG2094	Belongs to the DNA glycosylase MPG family
Tter_1171	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Tter_1172	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Tter_1173	COG0438	transferase activity, transferring glycosyl groups
Tter_1181	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Tter_1182	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Tter_1183	COG1960	acyl-CoA dehydrogenase activity
Tter_1186	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Tter_1187	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Tter_1187	COG0646	methionine synthase
Tter_1188	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Tter_1189	COG0372	Belongs to the citrate synthase family
Tter_1191	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Tter_1195	COG2409	Drug exporters of the RND superfamily
Tter_1197	COG1940	carbohydrate kinase activity
Tter_1201	COG1132	(ABC) transporter
Tter_1202	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Tter_1203	COG1051	belongs to the nudix hydrolase family
Tter_1204	COG0242	peptide deformylase activity
Tter_1205	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Tter_1206	COG0215	cysteine-tRNA ligase activity
Tter_1208	COG0400	carboxylic ester hydrolase activity
Tter_1209	COG0861	Integral membrane protein TerC family
Tter_1212	COG0626	cystathionine gamma-synthase activity
Tter_1213	COG1363	Peptidase, m42
Tter_1214	COG1574	metal-dependent hydrolase with the TIM-barrel fold
Tter_1216	COG0542	response to heat
Tter_1217	COG2223	nitrite transmembrane transporter activity
Tter_1219	COG0483	inositol monophosphate 1-phosphatase activity
Tter_1220	COG1116	anion transmembrane transporter activity
Tter_1221	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Tter_1222	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Tter_1223	COG0352	thiamine-phosphate diphosphorylase activity
Tter_1224	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Tter_1226	COG0492	ferredoxin-NADP+ reductase activity
Tter_1229	COG0318	PFAM AMP-dependent synthetase and ligase
Tter_1230	COG1575	Belongs to the MenA family. Type 1 subfamily
Tter_1231	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Tter_1232	COG0596	Alpha beta hydrolase
Tter_1233	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
Tter_1234	COG1169	isochorismate synthase
Tter_1235	COG0628	permease
Tter_1237	COG1470	cell adhesion involved in biofilm formation
Tter_1239	COG1012	belongs to the aldehyde dehydrogenase family
Tter_1240	COG0124	histidyl-tRNA synthetase
Tter_1242	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Tter_1243	COG0077	Prephenate dehydratase
Tter_1243	COG1605	Chorismate mutase
Tter_1245	COG1254	Belongs to the acylphosphatase family
Tter_1246	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Tter_1247	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Tter_1248	COG0159	tryptophan synthase activity
Tter_1249	COG0133	tryptophan synthase activity
Tter_1250	COG0135	phosphoribosylanthranilate isomerase activity
Tter_1251	COG0134	indole-3-glycerol-phosphate synthase activity
Tter_1252	COG0180	Tryptophanyl-tRNA synthetase
Tter_1253	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Tter_1257	COG1842	Phage shock protein A
Tter_1264	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Tter_1265	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Tter_1266	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Tter_1268	COG3409	Peptidoglycan-binding domain 1 protein
Tter_1268	COG0793	Belongs to the peptidase S41A family
Tter_1269	COG1426	Protein conserved in bacteria
Tter_1272	COG0792	nuclease activity
Tter_1273	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Tter_1274	COG0335	large ribosomal subunit rRNA binding
Tter_1277	COG4481	Protein conserved in bacteria
Tter_1279	COG0330	HflC and HflK could
Tter_1280	COG0556	nucleotide-excision repair
Tter_1282	COG1733	regulation of RNA biosynthetic process
Tter_1283	COG1132	(ABC) transporter
Tter_1284	COG2814	Major facilitator Superfamily
Tter_1285	COG1846	Transcriptional regulator
Tter_1289	COG0395	ABC-type sugar transport system, permease component
Tter_1290	COG1175	transmembrane transport
Tter_1293	COG0284	orotidine-5'-phosphate decarboxylase activity
Tter_1294	COG0598	Magnesium transport protein CorA
Tter_1296	COG1063	alcohol dehydrogenase
Tter_1297	COG1082	Xylose isomerase domain protein TIM barrel
Tter_1304	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Tter_1306	COG2226	methyltransferase
Tter_1307	COG1078	dGTPase activity
Tter_1308	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Tter_1314	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Tter_1315	COG0735	belongs to the Fur family
Tter_1316	COG3546	catalase activity
Tter_1321	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Tter_1322	COG0667	Aldo Keto reductase
Tter_1330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tter_1331	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Tter_1332	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Tter_1333	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Tter_1339	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Tter_1340	COG0113	porphobilinogen synthase activity
Tter_1342	COG0181	hydroxymethylbilane synthase activity
Tter_1344	COG0564	pseudouridine synthase activity
Tter_1345	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Tter_1346	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Tter_1347	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Tter_1348	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Tter_1349	COG0542	response to heat
Tter_1350	COG0539	negative regulation of cytoplasmic translation
Tter_1351	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Tter_1352	COG0628	permease
Tter_1354	COG0193	aminoacyl-tRNA hydrolase activity
Tter_1355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Tter_1356	COG1193	negative regulation of DNA recombination
Tter_1357	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Tter_1358	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Tter_1362	COG0762	integral membrane protein
Tter_1363	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Tter_1364	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Tter_1365	COG0142	geranyltranstransferase activity
Tter_1366	COG0322	excinuclease ABC activity
Tter_1368	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Tter_1370	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Tter_1371	COG0505	Belongs to the CarA family
Tter_1373	COG0540	Belongs to the ATCase OTCase family
Tter_1374	COG2233	PERMEase
Tter_1375	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Tter_1376	COG0768	penicillin binding
Tter_1379	COG2226	methyltransferase
Tter_1382	COG0105	UTP biosynthetic process
Tter_1386	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Tter_1387	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Tter_1388	COG2508	Transcriptional regulator
Tter_1389	COG0174	glutamine synthetase
Tter_1392	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Tter_1393	COG0315	cyclic pyranopterin monophosphate synthase activity
Tter_1394	COG4187	Peptidase family M20/M25/M40
Tter_1397	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Tter_1398	COG2201	protein-glutamate methylesterase activity
Tter_1399	COG0542	response to heat
Tter_1400	COG1793	dna ligase
Tter_1402	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Tter_1403	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Tter_1404	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Tter_1405	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Tter_1407	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Tter_1408	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Tter_1409	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Tter_1410	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Tter_1413	COG0316	Belongs to the HesB IscA family
Tter_1418	COG1196	nuclear chromosome segregation
Tter_1419	COG1120	ATPase activity
Tter_1420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Tter_1421	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Tter_1423	COG1847	R3H domain protein
Tter_1424	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Tter_1428	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Tter_1429	COG0740	serine-type endopeptidase activity
Tter_1430	COG0544	peptidyl-prolyl cis-trans isomerase activity
Tter_1432	COG2890	protein-(glutamine-N5) methyltransferase activity
Tter_1433	COG1316	TRANSCRIPTIONal
Tter_1435	COG0745	RESPONSE REGULATOR receiver
Tter_1436	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Tter_1437	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Tter_1441	COG1131	(ABC) transporter
Tter_1444	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Tter_1447	COG1028	Short-chain dehydrogenase reductase Sdr
Tter_1448	COG0561	phosphatase activity
Tter_1449	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Tter_1453	COG1028	Short-chain dehydrogenase reductase Sdr
Tter_1455	COG0328	RNA-DNA hybrid ribonuclease activity
Tter_1456	COG0671	phosphoesterase, PA-phosphatase related
Tter_1457	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Tter_1461	COG0463	Glycosyl transferase, family 2
Tter_1464	COG0697	spore germination
Tter_1466	COG0746	molybdenum cofactor guanylyltransferase activity
Tter_1471	COG2189	Belongs to the N(4) N(6)-methyltransferase family
Tter_1475	COG0366	Alpha amylase catalytic
Tter_1483	COG0525	valine-tRNA ligase activity
Tter_1484	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Tter_1485	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Tter_1486	COG0402	S-adenosylhomocysteine deaminase activity
Tter_1489	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Tter_1492	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Tter_1494	COG0745	RESPONSE REGULATOR receiver
Tter_1495	COG5002	protein histidine kinase activity
Tter_1496	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Tter_1497	COG0509	glycine decarboxylation via glycine cleavage system
Tter_1500	COG5002	protein histidine kinase activity
Tter_1505	COG1612	heme a metabolic process
Tter_1505	COG0109	protoheme IX farnesyltransferase activity
Tter_1506	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Tter_1507	COG1138	Cytochrome C-type biogenesis protein
Tter_1508	COG3088	subunit of a heme lyase
Tter_1511	COG2971	BadF BadG BcrA BcrD
Tter_1512	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Tter_1513	COG3876	Protein conserved in bacteria
Tter_1515	COG4589	Belongs to the CDS family
Tter_1517	COG0233	cytoplasmic translational termination
Tter_1518	COG0528	UMP kinase activity
Tter_1519	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Tter_1520	COG0052	Belongs to the universal ribosomal protein uS2 family
Tter_1521	COG1082	Xylose isomerase domain protein TIM barrel
Tter_1523	COG0673	inositol 2-dehydrogenase activity
Tter_1524	COG3962	Belongs to the TPP enzyme family
Tter_1525	COG3718	enzyme involved in inositol metabolism
Tter_1526	COG0673	inositol 2-dehydrogenase activity
Tter_1527	COG3958	Transketolase
Tter_1528	COG3959	Transketolase, thiamine diphosphate binding domain
Tter_1530	COG0747	negative chemotaxis
Tter_1531	COG1007	ATP synthesis coupled electron transport
Tter_1534	COG0713	ATP synthesis coupled electron transport
Tter_1536	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Tter_1537	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Tter_1542	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Tter_1543	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Tter_1544	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Tter_1546	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Tter_1547	COG1827	regulation of RNA biosynthetic process
Tter_1548	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Tter_1550	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Tter_1551	COG1104	cysteine desulfurase activity
Tter_1552	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tter_1553	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Tter_1555	COG1611	Belongs to the LOG family
Tter_1556	COG1846	Transcriptional regulator
Tter_1557	COG0477	Major facilitator Superfamily
Tter_1558	COG1418	mRNA catabolic process
Tter_1559	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Tter_1560	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Tter_1561	COG4956	integral membrane protein (PIN domain superfamily)
Tter_1562	COG0613	PHP domain protein
Tter_1564	COG3291	Pkd domain containing protein
Tter_1564	COG4412	M6 family metalloprotease domain protein
Tter_1571	COG0673	inositol 2-dehydrogenase activity
Tter_1572	COG0673	inositol 2-dehydrogenase activity
Tter_1577	COG0735	belongs to the Fur family
Tter_1578	COG3443	Belongs to the bacterial solute-binding protein 9 family
Tter_1578	COG0803	Belongs to the bacterial solute-binding protein 9 family
Tter_1579	COG1121	(ABC) transporter
Tter_1580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Tter_1582	COG1321	iron dependent repressor
Tter_1583	COG1914	H( )-stimulated, divalent metal cation uptake system
Tter_1587	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Tter_1588	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Tter_1595	COG0437	4 iron, 4 sulfur cluster binding
Tter_1600	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Tter_1604	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Tter_1605	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Tter_1607	COG0772	Belongs to the SEDS family
Tter_1608	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Tter_1610	COG0728	peptidoglycan biosynthetic process
Tter_1612	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Tter_1613	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Tter_1614	COG0768	penicillin binding
Tter_1617	COG2001	Belongs to the MraZ family
Tter_1619	COG4770	biotin carboxylase activity
Tter_1621	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Tter_1623	COG0346	lactoylglutathione lyase activity
Tter_1629	COG1077	Cell shape determining protein MreB Mrl
Tter_1630	COG2003	Belongs to the UPF0758 family
Tter_1631	COG0583	DNA-binding transcription factor activity
Tter_1632	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Tter_1634	COG0228	four-way junction DNA binding
Tter_1635	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Tter_1636	COG1388	LysM domain
Tter_1637	COG0745	RESPONSE REGULATOR receiver
Tter_1640	COG0805	protein transport
Tter_1641	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Tter_1642	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Tter_1643	COG0439	Biotin carboxylase
Tter_1644	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Tter_1645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Tter_1646	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Tter_1649	COG0742	ribosomal rna small subunit methyltransferase
Tter_1650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Tter_1651	COG1307	EDD domain protein, DegV family
Tter_1653	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Tter_1654	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Tter_1655	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Tter_1656	COG0004	ammonium transporteR
Tter_1658	COG0463	Glycosyl transferase, family 2
Tter_1659	COG0006	proline dipeptidase activity
Tter_1660	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Tter_1661	COG0511	ligase activity, forming carbon-carbon bonds
Tter_1663	COG1722	exodeoxyribonuclease VII activity
Tter_1664	COG4948	Mandelate Racemase Muconate Lactonizing
Tter_1665	COG0442	prolyl-tRNA aminoacylation
Tter_1666	COG0497	DNA recombination
Tter_1668	COG1555	photosystem II stabilization
Tter_1668	COG1596	polysaccharide export
Tter_1671	COG1250	3-hydroxyacyl-CoA dehydrogenase
Tter_1676	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Tter_1677	COG1691	(AIR) carboxylase
Tter_1680	COG1331	Highly conserved protein containing a thioredoxin domain
Tter_1682	COG0631	protein serine/threonine phosphatase activity
Tter_1683	COG0515	serine threonine protein kinase
Tter_1684	COG0515	serine threonine protein kinase
Tter_1684	COG2815	serine threonine protein kinase
Tter_1685	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Tter_1689	COG0640	Transcriptional regulator
Tter_1695	COG0822	iron-sulfur transferase activity
Tter_1696	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Tter_1697	COG0719	Fe-S assembly protein
Tter_1699	COG0396	ATPase activity
Tter_1700	COG1959	2 iron, 2 sulfur cluster binding
Tter_1701	COG0469	pyruvate kinase activity
Tter_1702	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Tter_1704	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Tter_1707	COG1192	Involved in chromosome partitioning
Tter_1708	COG1606	tRNA processing
Tter_1709	COG0823	Involved in the tonB-independent uptake of proteins
Tter_1714	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Tter_1715	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Tter_1716	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Tter_1718	COG0438	transferase activity, transferring glycosyl groups
Tter_1719	COG3706	GGDEF domain
Tter_1720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Tter_1723	COG0501	Belongs to the peptidase M48B family
Tter_1732	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Tter_1738	COG0714	Associated with various cellular activities
Tter_1741	COG1131	(ABC) transporter
Tter_1744	COG0589	response to stress
Tter_1745	COG0436	Aminotransferase
Tter_1748	COG1420	regulation of RNA biosynthetic process
Tter_1749	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Tter_1750	COG0443	Heat shock 70 kDa protein
Tter_1751	COG0484	heat shock protein binding
Tter_1753	COG0799	negative regulation of ribosome biogenesis
Tter_1755	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Tter_1757	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Tter_1758	COG1160	GTP binding
Tter_1763	COG0505	Belongs to the CarA family
Tter_1774	COG1131	(ABC) transporter
Tter_1775	COG1309	transcriptional regulator
Tter_1788	COG0237	dephospho-CoA kinase activity
Tter_1789	COG1185	polyribonucleotide nucleotidyltransferase activity
Tter_1790	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Tter_1795	COG0825	malonyl-CoA metabolic process
Tter_1796	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Tter_1801	COG4608	Belongs to the ABC transporter superfamily
Tter_1802	COG0444	Belongs to the ABC transporter superfamily
Tter_1804	COG0601	transmembrane transport
Tter_1805	COG0747	negative chemotaxis
Tter_1810	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Tter_1811	COG1597	lipid kinase activity
Tter_1814	COG0359	binds to the 23S rRNA
Tter_1815	COG0305	Participates in initiation and elongation during chromosome replication
Tter_1816	COG1484	DNA-dependent DNA replication
Tter_1817	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Tter_1821	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Tter_1822	COG0081	regulation of translation
Tter_1823	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Tter_1824	COG0250	Participates in transcription elongation, termination and antitermination
Tter_1825	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Tter_1826	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Tter_1827	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Tter_1828	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Tter_1834	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Tter_1835	COG0358	DNA primase activity
Tter_1837	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Tter_1838	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Tter_1839	COG4974	Belongs to the 'phage' integrase family
Tter_1841	COG0423	glycine-tRNA ligase activity
Tter_1843	COG0438	transferase activity, transferring glycosyl groups
Tter_1844	COG1442	glycosyl transferase family 8
Tter_1844	COG1216	Glycosyl transferase, family 2
Tter_1847	COG0438	transferase activity, transferring glycosyl groups
Tter_1848	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Tter_1850	COG0012	GTP binding
Tter_1852	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Tter_1855	COG1705	Flagellar rod assembly protein muramidase FlgJ
Tter_1855	COG1388	LysM domain
Tter_1861	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tter_1865	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Tter_1867	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Tter_1868	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Tter_1871	COG4867	von Willebrand factor, type A
Tter_1874	COG0419	ATPase involved in DNA repair
Tter_1881	COG0673	inositol 2-dehydrogenase activity
Tter_1898	COG1857	crispr-associated protein
Tter_1910	COG1082	Xylose isomerase domain protein TIM barrel
Tter_1913	COG2234	aminopeptidase activity
Tter_1916	COG0673	inositol 2-dehydrogenase activity
Tter_1919	COG1349	DNA-binding transcription factor activity
Tter_1920	COG0514	ATP-dependent DNA helicase (RecQ)
Tter_1923	COG2084	Dehydrogenase
Tter_1924	COG3622	Belongs to the hyi family
Tter_1925	COG0673	inositol 2-dehydrogenase activity
Tter_1926	COG3173	Aminoglycoside phosphotransferase
Tter_1927	COG0747	negative chemotaxis
Tter_1929	COG4948	Mandelate Racemase Muconate Lactonizing
Tter_1933	COG2814	Major facilitator Superfamily
Tter_1956	COG1649	PFAM Uncharacterised BCR, COG1649
Tter_1958	COG0129	dihydroxy-acid dehydratase activity
Tter_1959	COG1486	melibiose metabolic process
Tter_1962	COG1175	transmembrane transport
Tter_1963	COG1653	transport
Tter_1964	COG2186	Transcriptional regulator
Tter_1966	COG1028	Short-chain dehydrogenase reductase Sdr
Tter_1968	COG2207	Transcriptional regulator
Tter_1968	COG0662	Cupin 2, conserved barrel domain protein
Tter_1970	COG1063	alcohol dehydrogenase
Tter_1975	COG0667	Aldo Keto reductase
Tter_1976	COG0667	Aldo Keto reductase
Tter_1977	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tter_1979	COG2084	Dehydrogenase
Tter_1991	COG0395	ABC-type sugar transport system, permease component
Tter_1992	COG4209	transmembrane transport
Tter_1996	COG2186	Transcriptional regulator
Tter_1999	COG1653	transport
Tter_2000	COG1175	transmembrane transport
Tter_2002	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Tter_2003	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Tter_2004	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Tter_2005	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Tter_2006	COG1028	Short-chain dehydrogenase reductase Sdr
Tter_2008	COG1063	alcohol dehydrogenase
Tter_2011	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Tter_2013	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Tter_2014	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Tter_2015	COG1120	ATPase activity
Tter_2023	COG0395	ABC-type sugar transport system, permease component
Tter_2024	COG1175	transmembrane transport
Tter_2025	COG1653	transport
Tter_2034	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Tter_2035	COG3387	PFAM Glycoside hydrolase 15-related
Tter_2040	COG0395	ABC-type sugar transport system, permease component
Tter_2041	COG1175	transmembrane transport
Tter_2043	COG1349	DNA-binding transcription factor activity
Tter_2044	COG1304	FMN binding
Tter_2048	COG1819	glycosyl
Tter_2052	COG1175	transmembrane transport
Tter_2053	COG0395	ABC-type sugar transport system, permease component
Tter_2055	COG1063	alcohol dehydrogenase
Tter_2056	COG1063	alcohol dehydrogenase
Tter_2057	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Tter_2058	COG0735	belongs to the Fur family
Tter_2065	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Tter_2066	COG2205	protein histidine kinase activity
Tter_2069	COG0531	amino acid
Tter_2070	COG0586	Pfam SNARE associated Golgi protein
Tter_2072	COG4608	Belongs to the ABC transporter superfamily
Tter_2073	COG0747	negative chemotaxis
Tter_2074	COG0601	transmembrane transport
Tter_2075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Tter_2076	COG0444	Belongs to the ABC transporter superfamily
Tter_2078	COG0701	Predicted permease
Tter_2088	COG2205	protein histidine kinase activity
Tter_2091	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Tter_2093	COG0745	RESPONSE REGULATOR receiver
Tter_2094	COG0745	RESPONSE REGULATOR receiver
Tter_2095	COG2205	protein histidine kinase activity
Tter_2099	COG1881	PFAM PEBP family protein
Tter_2102	COG2226	methyltransferase
Tter_2103	COG0484	heat shock protein binding
Tter_2105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Tter_2107	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Tter_2108	COG0494	nUDIX hydrolase
Tter_2110	COG1122	ATPase activity
Tter_2113	COG0747	negative chemotaxis
Tter_2114	COG1649	PFAM Uncharacterised BCR, COG1649
Tter_2114	COG0726	polysaccharide deacetylase
Tter_2119	COG1028	Short-chain dehydrogenase reductase Sdr
Tter_2120	COG0745	RESPONSE REGULATOR receiver
Tter_2121	COG2205	protein histidine kinase activity
Tter_2122	COG0028	Belongs to the TPP enzyme family
Tter_2124	COG0006	proline dipeptidase activity
Tter_2125	COG0277	FAD linked oxidase domain protein
Tter_2125	COG0247	lactate metabolic process
Tter_2130	COG2971	BadF BadG BcrA BcrD
Tter_2131	COG0363	glucosamine-6-phosphate deaminase activity
Tter_2132	COG1486	melibiose metabolic process
Tter_2134	COG0673	inositol 2-dehydrogenase activity
Tter_2135	COG0395	ABC-type sugar transport system, permease component
Tter_2136	COG1175	transmembrane transport
Tter_2138	COG0673	inositol 2-dehydrogenase activity
Tter_2139	COG1940	carbohydrate kinase activity
Tter_2144	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Tter_2147	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Tter_2151	COG2151	metal-sulfur cluster biosynthetic enzyme
Tter_2155	COG1276	copper resistance
Tter_2168	COG2239	Acts as a magnesium transporter
Tter_2170	COG0778	Nitroreductase
Tter_2171	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Tter_2172	COG0601	transmembrane transport
Tter_2173	COG4106	trans-aconitate 2-methyltransferase activity
Tter_2174	COG0577	efflux transmembrane transporter activity
Tter_2175	COG1136	(ABC) transporter
Tter_2176	COG5002	protein histidine kinase activity
Tter_2177	COG0745	RESPONSE REGULATOR receiver
Tter_2179	COG1253	flavin adenine dinucleotide binding
Tter_2184	COG2264	protein methyltransferase activity
Tter_2189	COG1215	transferase activity, transferring glycosyl groups
Tter_2192	COG0745	RESPONSE REGULATOR receiver
Tter_2192	COG3706	GGDEF domain
Tter_2194	COG0784	Response regulator, receiver
Tter_2194	COG2205	protein histidine kinase activity
Tter_2194	COG5002	protein histidine kinase activity
Tter_2199	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Tter_2202	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Tter_2204	COG1085	galactose-1-phosphate uridylyltransferase
Tter_2205	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Tter_2207	COG0395	ABC-type sugar transport system, permease component
Tter_2208	COG1175	transmembrane transport
Tter_2212	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Tter_2214	COG4948	Mandelate Racemase Muconate Lactonizing
Tter_2216	COG0395	ABC-type sugar transport system, permease component
Tter_2217	COG1175	transmembrane transport
Tter_2219	COG1609	Transcriptional regulator
Tter_2220	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Tter_2221	COG1129	ABC transporter
Tter_2223	COG0431	NADPH-dependent FMN reductase
Tter_2224	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Tter_2225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tter_2226	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Tter_2227	COG1116	anion transmembrane transporter activity
Tter_2230	COG0450	alkyl hydroperoxide reductase
Tter_2236	COG3608	succinylglutamate desuccinylase aspartoacylase
Tter_2236	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Tter_2237	COG0534	Mate efflux family protein
Tter_2238	COG2132	Multicopper oxidase
Tter_2246	COG2003	Belongs to the UPF0758 family
Tter_2247	COG0673	inositol 2-dehydrogenase activity
Tter_2249	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Tter_2252	COG1070	Carbohydrate kinase
Tter_2253	COG4952	isomerase
Tter_2254	COG3347	Dehydrogenase
Tter_2254	COG1028	Short-chain dehydrogenase reductase Sdr
Tter_2256	COG1139	Iron-sulfur cluster binding protein
Tter_2261	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Tter_2265	COG0673	inositol 2-dehydrogenase activity
Tter_2267	COG4948	Mandelate Racemase Muconate Lactonizing
Tter_2269	COG1063	alcohol dehydrogenase
Tter_2271	COG1028	Short-chain dehydrogenase reductase Sdr
Tter_2272	COG1063	alcohol dehydrogenase
Tter_2273	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
Tter_2274	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tter_2275	COG0714	Associated with various cellular activities
Tter_2278	COG0366	Alpha amylase catalytic
Tter_2278	COG3103	Sh3 type 3 domain protein
Tter_2280	COG2409	Drug exporters of the RND superfamily
Tter_2283	COG1993	acr, cog1993
Tter_2284	COG2186	Transcriptional regulator
Tter_2285	COG1397	ADP-ribosylglycohydrolase
Tter_2287	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Tter_2292	COG1175	transmembrane transport
Tter_2293	COG0395	ABC-type sugar transport system, permease component
Tter_2294	COG1653	transport
Tter_2296	COG0484	heat shock protein binding
Tter_2301	COG0395	ABC-type sugar transport system, permease component
Tter_2302	COG1175	transmembrane transport
Tter_2304	COG1609	Transcriptional regulator
Tter_2306	COG1785	Belongs to the alkaline phosphatase family
Tter_2307	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Tter_2309	COG1028	Short-chain dehydrogenase reductase Sdr
Tter_2310	COG2721	sulfolactate sulfo-lyase activity
Tter_2315	COG1653	transport
Tter_2316	COG1175	transmembrane transport
Tter_2317	COG0395	ABC-type sugar transport system, permease component
Tter_2319	COG0346	lactoylglutathione lyase activity
Tter_2322	COG1846	Transcriptional regulator
Tter_2323	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Tter_2323	COG0473	3-isopropylmalate dehydrogenase activity
Tter_2324	COG3345	alpha-galactosidase
Tter_2326	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Tter_2328	COG4208	sulfate ABC transporter
Tter_2329	COG3842	ATPase activity
Tter_2333	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Tter_2334	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Tter_2338	COG2239	Acts as a magnesium transporter
Tter_2339	COG1914	H( )-stimulated, divalent metal cation uptake system
Tter_2343	COG2323	membrane
Tter_2345	COG0657	acetylesterase activity
Tter_2345	COG2755	lipolytic protein G-D-S-L family
Tter_2346	COG2814	Major facilitator Superfamily
Tter_2347	COG0534	Mate efflux family protein
Tter_2350	COG1132	(ABC) transporter
Tter_2351	COG1132	(ABC) transporter
Tter_2353	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Tter_2353	COG2010	Cytochrome c
Tter_2354	COG2080	2 iron, 2 sulfur cluster binding
Tter_2356	COG4977	sequence-specific DNA binding
Tter_2356	COG1917	Cupin 2, conserved barrel domain protein
Tter_2357	COG0730	response to heat
Tter_2361	COG1028	Short-chain dehydrogenase reductase Sdr
Tter_2365	COG0579	oxidoreductase
Tter_2366	COG2268	Band 7 protein
Tter_2371	COG5002	protein histidine kinase activity
Tter_2374	COG5002	protein histidine kinase activity
Tter_2376	COG0563	adenylate kinase activity
Tter_2385	COG1609	Transcriptional regulator
Tter_2398	COG1131	(ABC) transporter
Tter_2423	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Tter_2430	COG1518	maintenance of DNA repeat elements
Tter_2431	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
Tter_2433	COG1073	alpha beta
Tter_2437	COG4535	Mg2 and Co2 transporter CorC
Tter_2442	COG0667	Aldo Keto reductase
Tter_2444	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Tter_2445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Tter_2446	COG2197	response regulator
Tter_2447	COG3250	beta-galactosidase activity
Tter_2452	COG0395	ABC-type sugar transport system, permease component
Tter_2453	COG1175	transmembrane transport
Tter_2454	COG0277	FAD linked oxidase domain protein
Tter_2456	COG1830	Aldolase
Tter_2458	COG1105	Belongs to the carbohydrate kinase PfkB family
Tter_2459	COG1940	carbohydrate kinase activity
Tter_2460	COG1349	DNA-binding transcription factor activity
Tter_2461	COG3250	beta-galactosidase activity
Tter_2464	COG0789	Transcriptional regulator
Tter_2465	COG2217	Heavy metal translocating P-type atpase
Tter_2470	COG0459	protein refolding
Tter_2473	COG1175	transmembrane transport
Tter_2475	COG1609	Transcriptional regulator
Tter_2480	COG1070	Carbohydrate kinase
Tter_2481	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Tter_2482	COG0698	ribose 5-phosphate isomerase
Tter_2483	COG2376	Dihydroxyacetone kinase
Tter_2484	COG2376	Dihydroxyacetone kinase
Tter_2485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Tter_2486	COG1349	DNA-binding transcription factor activity
Tter_2488	COG1653	transport
Tter_2489	COG1175	transmembrane transport
Tter_2490	COG0395	ABC-type sugar transport system, permease component
Tter_2491	COG3842	ATPase activity
Tter_2493	COG1070	Carbohydrate kinase
Tter_2494	COG0588	phosphoglycerate mutase activity
Tter_2497	COG0395	ABC-type sugar transport system, permease component
Tter_2500	COG0395	ABC-type sugar transport system, permease component
Tter_2503	COG1609	Transcriptional regulator
Tter_2506	COG1175	transmembrane transport
Tter_2507	COG0395	ABC-type sugar transport system, permease component
Tter_2510	COG1414	Transcriptional regulator
Tter_2511	COG1175	transmembrane transport
Tter_2512	COG0395	ABC-type sugar transport system, permease component
Tter_2517	COG1028	Short-chain dehydrogenase reductase Sdr
Tter_2518	COG4948	Mandelate Racemase Muconate Lactonizing
Tter_2519	COG0457	Tetratricopeptide repeat
Tter_2522	COG0395	ABC-type sugar transport system, permease component
Tter_2523	COG1175	transmembrane transport
Tter_2527	COG1175	transmembrane transport
Tter_2528	COG0395	ABC-type sugar transport system, permease component
Tter_2535	COG2223	nitrite transmembrane transporter activity
Tter_2538	COG0437	4 iron, 4 sulfur cluster binding
Tter_2539	COG0243	molybdopterin cofactor binding
Tter_2543	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Tter_2544	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Tter_2547	COG0589	response to stress
Tter_2548	COG2197	response regulator
Tter_2563	COG5002	protein histidine kinase activity
Tter_2564	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Tter_2568	COG0655	NAD(P)H dehydrogenase (quinone) activity
Tter_2571	COG0456	acetyltransferase
Tter_2572	COG0395	ABC-type sugar transport system, permease component
Tter_2573	COG1175	transmembrane transport
Tter_2582	COG1937	Protein conserved in bacteria
Tter_2584	COG2217	Heavy metal translocating P-type atpase
Tter_2585	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Tter_2586	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Tter_2590	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Tter_2591	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Tter_2592	COG0215	cysteine-tRNA ligase activity
Tter_2599	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Tter_2603	COG0673	inositol 2-dehydrogenase activity
Tter_2604	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Tter_2605	COG1472	Belongs to the glycosyl hydrolase 3 family
Tter_2606	COG0673	inositol 2-dehydrogenase activity
Tter_2609	COG1131	(ABC) transporter
Tter_2610	COG3119	arylsulfatase activity
Tter_2611	COG1846	Transcriptional regulator
Tter_2612	COG0477	Major facilitator Superfamily
Tter_2613	COG1349	DNA-binding transcription factor activity
Tter_2615	COG1175	transmembrane transport
Tter_2616	COG0395	ABC-type sugar transport system, permease component
Tter_2617	COG1486	melibiose metabolic process
Tter_2620	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Tter_2620	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Tter_2621	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Tter_2621	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Tter_2622	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Tter_2623	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Tter_2629	COG2261	transglycosylase associated protein
Tter_2630	COG1595	DNA-templated transcription, initiation
Tter_2633	COG3540	Alkaline phosphatase
Tter_2634	COG0730	response to heat
Tter_2636	COG2323	membrane
Tter_2648	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Tter_2656	COG1940	carbohydrate kinase activity
Tter_2662	COG2267	carboxylic ester hydrolase activity
Tter_2665	COG1111	helicase
Tter_2665	COG1205	dead DEAH box helicase
Tter_2667	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Tter_2668	COG0306	phosphate transporter
Tter_2673	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Tter_2674	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Tter_2675	COG0028	Belongs to the TPP enzyme family
Tter_2679	COG0477	Major facilitator Superfamily
Tter_2684	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tter_2686	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Tter_2687	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Tter_2689	COG1268	BioY protein
Tter_2696	COG0363	glucosamine-6-phosphate deaminase activity
Tter_2699	COG1609	Transcriptional regulator
Tter_2700	COG0673	inositol 2-dehydrogenase activity
Tter_2701	COG0395	ABC-type sugar transport system, permease component
Tter_2704	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Tter_2707	COG2855	membrane
Tter_2711	COG1573	uracil-dna glycosylase
Tter_2720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Tter_2721	COG0730	response to heat
Tter_2722	COG0640	Transcriptional regulator
Tter_2723	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Tter_2729	COG0584	glycerophosphoryl diester phosphodiesterase
Tter_2730	COG0800	Aldolase
Tter_2740	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Tter_2741	COG0581	inorganic phosphate transmembrane transporter activity
Tter_2745	COG4608	Belongs to the ABC transporter superfamily
Tter_2746	COG0444	Belongs to the ABC transporter superfamily
Tter_2747	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Tter_2752	COG2423	ornithine cyclodeaminase activity
Tter_2758	COG2226	methyltransferase
Tter_2763	COG0066	3-isopropylmalate dehydratase activity
Tter_2767	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Tter_2767	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Tter_2768	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Tter_2773	COG1028	Short-chain dehydrogenase reductase Sdr
Tter_2788	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tter_2795	COG0438	transferase activity, transferring glycosyl groups
Tter_2799	COG0463	Glycosyl transferase, family 2
Tter_2799	COG1216	Glycosyl transferase, family 2
Tter_2806	COG0730	response to heat
Tter_2807	COG0438	transferase activity, transferring glycosyl groups
Tter_2811	COG0022	dehydrogenase e1 component
Tter_2812	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Tter_2813	COG0508	dehydrogenase complex catalyzes the overall conversion of
Tter_2814	COG0673	inositol 2-dehydrogenase activity
Tter_2815	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Tter_2823	COG1132	(ABC) transporter
Tter_2833	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Tter_2834	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Tter_2843	COG2095	MarC family integral membrane protein
Tter_2855	COG0640	Transcriptional regulator
Tter_2857	COG0617	tRNA 3'-terminal CCA addition
Tter_2866	COG0726	polysaccharide deacetylase
Tter_2867	COG0745	RESPONSE REGULATOR receiver
Tter_2868	COG5002	protein histidine kinase activity
Tter_2870	COG0704	Plays a role in the regulation of phosphate uptake