locus-tag	class	description
CYL17_00010	COG1136	(ABC) transporter
CYL17_00025	COG2205	protein histidine kinase activity
CYL17_00030	COG0745	RESPONSE REGULATOR receiver
CYL17_00035	COG0579	oxidoreductase
CYL17_00055	COG1695	Transcriptional regulator
CYL17_00070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CYL17_00080	COG0667	Aldo Keto reductase
CYL17_00100	COG2252	PERMEase
CYL17_00120	COG1278	Cold shock
CYL17_00135	COG3973	AAA domain
CYL17_00140	COG0459	protein refolding
CYL17_00150	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CYL17_00180	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
CYL17_00185	COG4608	Belongs to the ABC transporter superfamily
CYL17_00195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CYL17_00200	COG0601	transmembrane transport
CYL17_00215	COG1134	teichoic acid transport
CYL17_00220	COG1881	PFAM PEBP family protein
CYL17_00235	COG0416	fatty acid biosynthetic process
CYL17_00240	COG0018	arginyl-trna synthetase
CYL17_00250	COG1799	cell septum assembly
CYL17_00280	COG0243	molybdopterin cofactor binding
CYL17_00295	COG1960	acyl-CoA dehydrogenase activity
CYL17_00310	COG0508	dehydrogenase complex catalyzes the overall conversion of
CYL17_00315	COG0022	dehydrogenase e1 component
CYL17_00330	COG0477	Major facilitator Superfamily
CYL17_00340	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CYL17_00350	COG0047	phosphoribosylformylglycinamidine synthase activity
CYL17_00355	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CYL17_00380	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CYL17_00405	COG1309	transcriptional regulator
CYL17_00420	COG0860	N-Acetylmuramoyl-L-alanine amidase
CYL17_00425	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CYL17_00450	COG0167	dihydroorotate dehydrogenase activity
CYL17_00505	COG1960	acyl-CoA dehydrogenase activity
CYL17_00520	COG0730	response to heat
CYL17_00530	COG1797	cobyrinic acid a,c-diamide synthase activity
CYL17_00540	COG2205	protein histidine kinase activity
CYL17_00545	COG3189	MarR family transcriptional regulator
CYL17_00575	COG1302	Protein conserved in bacteria
CYL17_00630	COG2197	response regulator
CYL17_00645	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CYL17_00660	COG2188	Transcriptional regulator
CYL17_00690	COG1937	Protein conserved in bacteria
CYL17_00695	COG0438	transferase activity, transferring glycosyl groups
CYL17_00705	COG2181	nitrate reductase activity
CYL17_00705	COG0247	lactate metabolic process
CYL17_00710	COG1309	transcriptional regulator
CYL17_00715	COG2226	methyltransferase
CYL17_00720	COG1082	Xylose isomerase domain protein TIM barrel
CYL17_00725	COG2226	methyltransferase
CYL17_00730	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CYL17_00740	COG1194	a g-specific adenine glycosylase
CYL17_00765	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CYL17_00780	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CYL17_00785	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CYL17_00790	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CYL17_00795	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CYL17_00800	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CYL17_00815	COG1690	Belongs to the RtcB family
CYL17_00820	COG1131	(ABC) transporter
CYL17_00845	COG1131	(ABC) transporter
CYL17_00860	COG2124	cytochrome p450
CYL17_00865	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CYL17_00870	COG0649	NAD binding
CYL17_00880	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CYL17_00885	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CYL17_00895	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CYL17_00900	COG0302	gtp cyclohydrolase
CYL17_00905	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CYL17_00915	COG0037	tRNA processing
CYL17_00925	COG2027	D-alanyl-D-alanine carboxypeptidase
CYL17_00930	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CYL17_00935	COG3883	PFAM NLP P60 protein
CYL17_00935	COG0791	NLP P60 protein
CYL17_00945	COG3268	Saccharopine dehydrogenase
CYL17_00965	COG0076	glutamate decarboxylase activity
CYL17_00970	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CYL17_01005	COG0470	DNA polymerase III
CYL17_01010	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CYL17_01015	COG1408	metallophosphoesterase
CYL17_01020	COG1754	DNA topoisomerase type I activity
CYL17_01020	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CYL17_01040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CYL17_01080	COG1131	(ABC) transporter
CYL17_01155	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CYL17_01165	COG1120	ATPase activity
CYL17_01170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CYL17_01195	COG2815	serine threonine protein kinase
CYL17_01195	COG0515	serine threonine protein kinase
CYL17_01215	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CYL17_01235	COG1482	cell wall glycoprotein biosynthetic process
CYL17_01245	COG1609	Transcriptional regulator
CYL17_01265	COG2815	serine threonine protein kinase
CYL17_01265	COG0515	serine threonine protein kinase
CYL17_01295	COG2890	protein-(glutamine-N5) methyltransferase activity
CYL17_01300	COG1309	transcriptional regulator
CYL17_01320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYL17_01340	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CYL17_01345	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CYL17_01385	COG0590	tRNA wobble adenosine to inosine editing
CYL17_01400	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CYL17_01415	COG2186	Transcriptional regulator
CYL17_01420	COG0592	DNA-directed DNA polymerase activity
CYL17_01425	COG2197	response regulator
CYL17_01435	COG1131	(ABC) transporter
CYL17_01450	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CYL17_01455	COG1733	regulation of RNA biosynthetic process
CYL17_01460	COG0305	Participates in initiation and elongation during chromosome replication
CYL17_01465	COG0534	Mate efflux family protein
CYL17_01475	COG0765	amino acid transport
CYL17_01480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CYL17_01485	COG0359	binds to the 23S rRNA
CYL17_01490	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CYL17_01500	COG0360	Binds together with S18 to 16S ribosomal RNA
CYL17_01525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CYL17_01540	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CYL17_01550	COG0617	tRNA 3'-terminal CCA addition
CYL17_01570	COG2815	serine threonine protein kinase
CYL17_01570	COG0515	serine threonine protein kinase
CYL17_01575	COG1595	DNA-templated transcription, initiation
CYL17_01585	COG0492	ferredoxin-NADP+ reductase activity
CYL17_01590	COG3118	belongs to the thioredoxin family
CYL17_01600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CYL17_01605	COG1181	Belongs to the D-alanine--D-alanine ligase family
CYL17_01615	COG1695	Transcriptional regulator
CYL17_01640	COG1192	Involved in chromosome partitioning
CYL17_01645	COG0357	Ribosomal RNA small subunit methyltransferase G
CYL17_01660	COG0706	membrane insertase activity
CYL17_01670	COG0594	ribonuclease P activity
CYL17_01675	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CYL17_01680	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CYL17_01685	COG0592	DNA-directed DNA polymerase activity
CYL17_01690	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CYL17_01695	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CYL17_01700	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CYL17_01705	COG0187	DNA topoisomerase II activity
CYL17_01710	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CYL17_01725	COG1742	UPF0060 membrane protein
CYL17_01750	COG2608	mercury ion transmembrane transporter activity
CYL17_01755	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CYL17_01770	COG4604	ABC transporter, ATP-binding protein
CYL17_01775	COG4605	iron ion homeostasis
CYL17_01780	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CYL17_01785	COG4607	ABC-type enterochelin transport system periplasmic component
CYL17_01810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CYL17_01850	COG1215	transferase activity, transferring glycosyl groups
CYL17_01875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CYL17_01885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CYL17_01905	COG1316	TRANSCRIPTIONal
CYL17_01930	COG1716	ATPase activity
CYL17_01945	COG0768	penicillin binding
CYL17_01950	COG0515	serine threonine protein kinase
CYL17_01955	COG0515	serine threonine protein kinase
CYL17_02000	COG0840	transmembrane signaling receptor activity
CYL17_02020	COG1175	transmembrane transport
CYL17_02025	COG1653	transport
CYL17_02040	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CYL17_02045	COG1278	Cold shock
CYL17_02050	COG0561	phosphatase activity
CYL17_02130	COG0494	nUDIX hydrolase
CYL17_02140	COG2188	Transcriptional regulator
CYL17_02170	COG1203	CRISPR-associated helicase, Cas3
CYL17_02180	COG1518	maintenance of DNA repeat elements
CYL17_02185	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CYL17_02265	COG1799	cell septum assembly
CYL17_02270	COG1797	cobyrinic acid a,c-diamide synthase activity
CYL17_02350	COG0515	serine threonine protein kinase
CYL17_02355	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CYL17_02385	COG3391	amine dehydrogenase activity
CYL17_02470	COG1595	DNA-templated transcription, initiation
CYL17_02480	COG1846	Transcriptional regulator
CYL17_02520	COG2814	Major facilitator Superfamily
CYL17_02530	COG3226	Transcriptional regulator
CYL17_02540	COG1322	Protein conserved in bacteria
CYL17_02545	COG1525	nuclease
CYL17_02550	COG1115	amino acid carrier protein
CYL17_02565	COG2207	Transcriptional regulator
CYL17_02565	COG3708	Transcriptional regulator
CYL17_02585	COG0633	Ferredoxin
CYL17_02585	COG0543	2 iron, 2 sulfur cluster binding
CYL17_02590	COG1151	hydroxylamine reductase activity
CYL17_02605	COG1522	sequence-specific DNA binding
CYL17_02640	COG1070	Carbohydrate kinase
CYL17_02660	COG2018	Roadblock/LC7 domain
CYL17_02715	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CYL17_02725	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CYL17_02730	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CYL17_02735	COG0151	Belongs to the GarS family
CYL17_02745	COG1309	transcriptional regulator
CYL17_02760	COG0584	glycerophosphoryl diester phosphodiesterase
CYL17_02765	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CYL17_02790	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CYL17_02800	COG1432	Conserved Protein
CYL17_02810	COG5002	protein histidine kinase activity
CYL17_02810	COG0784	Response regulator, receiver
CYL17_02815	COG2770	Histidine kinase
CYL17_02815	COG2208	phosphoserine phosphatase activity
CYL17_02820	COG2226	methyltransferase
CYL17_02860	COG1408	metallophosphoesterase
CYL17_02870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CYL17_02880	COG0003	Pfam Anion-transporting ATPase
CYL17_02905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CYL17_02925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CYL17_02935	COG0596	Alpha beta hydrolase
CYL17_02945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CYL17_02990	COG1111	helicase
CYL17_02990	COG1205	dead DEAH box helicase
CYL17_02995	COG1366	Belongs to the anti-sigma-factor antagonist family
CYL17_03005	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CYL17_03015	COG3830	Belongs to the UPF0237 family
CYL17_03015	COG0560	Phosphoserine phosphatase
CYL17_03025	COG4585	Histidine kinase
CYL17_03030	COG2197	response regulator
CYL17_03035	COG1119	ATPase activity
CYL17_03070	COG0753	catalase activity
CYL17_03085	COG1309	transcriptional regulator
CYL17_03105	COG0542	response to heat
CYL17_03110	COG0789	Transcriptional regulator
CYL17_03115	COG0484	heat shock protein binding
CYL17_03120	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CYL17_03125	COG0443	Heat shock 70 kDa protein
CYL17_03135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CYL17_03140	COG0123	including yeast histone deacetylase and acetoin utilization protein
CYL17_03180	COG1595	DNA-templated transcription, initiation
CYL17_03195	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CYL17_03200	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CYL17_03205	COG0181	hydroxymethylbilane synthase activity
CYL17_03215	COG0113	porphobilinogen synthase activity
CYL17_03225	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CYL17_03235	COG0406	alpha-ribazole phosphatase activity
CYL17_03240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CYL17_03245	COG0785	Cytochrome C biogenesis protein
CYL17_03255	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CYL17_03285	COG2226	methyltransferase
CYL17_03300	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYL17_03305	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYL17_03310	COG0649	NAD binding
CYL17_03325	COG1034	ATP synthesis coupled electron transport
CYL17_03330	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CYL17_03335	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYL17_03360	COG1007	ATP synthesis coupled electron transport
CYL17_03365	COG0142	geranyltranstransferase activity
CYL17_03380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CYL17_03415	COG0697	spore germination
CYL17_03425	COG0444	Belongs to the ABC transporter superfamily
CYL17_03430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CYL17_03440	COG0747	negative chemotaxis
CYL17_03455	COG1013	pyruvate-flavodoxin oxidoreductase activity
CYL17_03460	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CYL17_03460	COG0674	pyruvate-flavodoxin oxidoreductase activity
CYL17_03465	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYL17_03470	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYL17_03475	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYL17_03480	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CYL17_03490	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYL17_03500	COG0713	ATP synthesis coupled electron transport
CYL17_03515	COG1007	ATP synthesis coupled electron transport
CYL17_03520	COG0501	Belongs to the peptidase M48B family
CYL17_03530	COG0765	amino acid transport
CYL17_03535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CYL17_03550	COG1666	GTP binding
CYL17_03615	COG0494	nUDIX hydrolase
CYL17_03645	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CYL17_03650	COG1247	-acetyltransferase
CYL17_03655	COG0640	Transcriptional regulator
CYL17_03685	COG1366	Belongs to the anti-sigma-factor antagonist family
CYL17_03710	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CYL17_03715	COG2030	dehydratase
CYL17_03725	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CYL17_03730	COG2119	membrane
CYL17_03735	COG1672	PFAM Archaeal ATPase
CYL17_03735	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CYL17_03745	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CYL17_03750	COG1012	belongs to the aldehyde dehydrogenase family
CYL17_03755	COG1012	belongs to the aldehyde dehydrogenase family
CYL17_03770	COG0321	lipoyl(octanoyl) transferase activity
CYL17_03780	COG0803	Belongs to the bacterial solute-binding protein 9 family
CYL17_03785	COG1121	(ABC) transporter
CYL17_03795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CYL17_03835	COG0640	Transcriptional regulator
CYL17_03840	COG1902	pentaerythritol trinitrate reductase activity
CYL17_03845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYL17_03865	COG3629	intracellular signal transduction
CYL17_03865	COG3903	Transcriptional regulator
CYL17_03870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CYL17_03875	COG3509	depolymerase
CYL17_03900	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CYL17_03900	COG0517	IMP dehydrogenase activity
CYL17_03900	COG0617	tRNA 3'-terminal CCA addition
CYL17_03905	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CYL17_03910	COG1993	acr, cog1993
CYL17_03915	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CYL17_03960	COG1309	transcriptional regulator
CYL17_03970	COG0559	Belongs to the binding-protein-dependent transport system permease family
CYL17_03990	COG4326	sporulation control protein
CYL17_03995	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CYL17_04000	COG1309	transcriptional regulator
CYL17_04105	COG0183	Belongs to the thiolase family
CYL17_04115	COG0640	Transcriptional regulator
CYL17_04120	COG0402	S-adenosylhomocysteine deaminase activity
CYL17_04185	COG0717	Belongs to the dCTP deaminase family
CYL17_04200	COG0456	acetyltransferase
CYL17_04205	COG0737	Belongs to the 5'-nucleotidase family
CYL17_04210	COG0745	RESPONSE REGULATOR receiver
CYL17_04245	COG2897	thiosulfate sulfurtransferase activity
CYL17_04290	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CYL17_04295	COG3442	glutamine amidotransferase
CYL17_04305	COG4044	May play a role in the intracellular transport of hydrophobic ligands
CYL17_04310	COG0735	belongs to the Fur family
CYL17_04315	COG1366	Belongs to the anti-sigma-factor antagonist family
CYL17_04320	COG1366	Belongs to the anti-sigma-factor antagonist family
CYL17_04325	COG2172	sigma factor antagonist activity
CYL17_04335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CYL17_04335	COG2205	protein histidine kinase activity
CYL17_04345	COG0354	folic acid binding
CYL17_04350	COG1490	D-aminoacyl-tRNA deacylase activity
CYL17_04365	COG0598	Magnesium transport protein CorA
CYL17_04385	COG0501	Belongs to the peptidase M48B family
CYL17_04410	COG0438	transferase activity, transferring glycosyl groups
CYL17_04420	COG0588	phosphoglycerate mutase activity
CYL17_04430	COG5002	protein histidine kinase activity
CYL17_04445	COG1329	Transcriptional regulator
CYL17_04450	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CYL17_04470	COG0215	cysteine-tRNA ligase activity
CYL17_04490	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CYL17_04505	COG0310	cobalt ion transport
CYL17_04515	COG1122	ATPase activity
CYL17_04525	COG1024	Enoyl-CoA hydratase
CYL17_04535	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CYL17_04545	COG0259	pyridoxamine-phosphate oxidase activity
CYL17_04550	COG1573	uracil-dna glycosylase
CYL17_04565	COG1960	acyl-CoA dehydrogenase activity
CYL17_04605	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CYL17_04610	COG0436	Aminotransferase
CYL17_04630	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CYL17_04635	COG0081	regulation of translation
CYL17_04650	COG0222	ribosome binding
CYL17_04655	COG0085	RNA polymerase activity
CYL17_04660	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CYL17_04665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CYL17_04670	COG2124	cytochrome p450
CYL17_04675	COG2124	cytochrome p450
CYL17_04680	COG1309	transcriptional regulator
CYL17_04720	COG1473	amidohydrolase
CYL17_04725	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CYL17_04730	COG0049	tRNA binding
CYL17_04735	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CYL17_04745	COG0051	transcription antitermination factor activity, RNA binding
CYL17_04750	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CYL17_04755	COG0088	Forms part of the polypeptide exit tunnel
CYL17_04760	COG0089	rRNA binding
CYL17_04765	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CYL17_04770	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CYL17_04775	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CYL17_04780	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CYL17_04785	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CYL17_04790	COG0255	Belongs to the universal ribosomal protein uL29 family
CYL17_04795	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CYL17_04800	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CYL17_04805	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CYL17_04810	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CYL17_04815	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CYL17_04820	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CYL17_04825	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CYL17_04830	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CYL17_04835	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CYL17_04840	COG1841	ribosomal large subunit assembly
CYL17_04845	COG0200	Binds to the 23S rRNA
CYL17_04855	COG0563	adenylate kinase activity
CYL17_04880	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CYL17_04885	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CYL17_04890	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CYL17_04895	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CYL17_04900	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CYL17_04905	COG0202	RNA polymerase activity
CYL17_04910	COG0203	ribosomal protein L17
CYL17_04915	COG0101	tRNA pseudouridine synthase activity
CYL17_04935	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CYL17_04940	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CYL17_04945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CYL17_04955	COG1131	(ABC) transporter
CYL17_04970	COG1072	(Pantothenic acid kinase))
CYL17_04975	COG0736	holo-[acyl-carrier-protein] synthase activity
CYL17_04985	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CYL17_04995	COG0802	atpase or kinase
CYL17_05015	COG1214	PFAM Peptidase M22, glycoprotease
CYL17_05015	COG0456	acetyltransferase
CYL17_05020	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CYL17_05035	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CYL17_05040	COG0459	protein refolding
CYL17_05045	COG1595	DNA-templated transcription, initiation
CYL17_05060	COG0516	GMP reductase activity
CYL17_05065	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CYL17_05070	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CYL17_05075	COG1012	belongs to the aldehyde dehydrogenase family
CYL17_05085	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CYL17_05085	COG0519	Catalyzes the synthesis of GMP from XMP
CYL17_05095	COG0789	Transcriptional regulator
CYL17_05105	COG0726	polysaccharide deacetylase
CYL17_05115	COG0463	Glycosyl transferase, family 2
CYL17_05120	COG1216	Glycosyl transferase, family 2
CYL17_05125	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CYL17_05135	COG0438	transferase activity, transferring glycosyl groups
CYL17_05145	COG0457	Tetratricopeptide repeat
CYL17_05190	COG2197	response regulator
CYL17_05200	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CYL17_05215	COG0045	succinate-CoA ligase (ADP-forming) activity
CYL17_05245	COG0138	bifunctional purine biosynthesis protein purh
CYL17_05250	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CYL17_05260	COG0372	Belongs to the citrate synthase family
CYL17_05290	COG1253	flavin adenine dinucleotide binding
CYL17_05295	COG0180	Tryptophanyl-tRNA synthetase
CYL17_05305	COG1686	Belongs to the peptidase S11 family
CYL17_05315	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CYL17_05320	COG1473	amidohydrolase
CYL17_05320	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CYL17_05325	COG1744	ABC transporter substrate-binding protein PnrA-like
CYL17_05330	COG3845	ABC transporter
CYL17_05335	COG4603	Belongs to the binding-protein-dependent transport system permease family
CYL17_05340	COG1079	Belongs to the binding-protein-dependent transport system permease family
CYL17_05360	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CYL17_05370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CYL17_05395	COG4770	biotin carboxylase activity
CYL17_05405	COG1674	ftsk spoiiie
CYL17_05430	COG1432	Conserved Protein
CYL17_05440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CYL17_05445	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CYL17_05460	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CYL17_05470	COG2193	ferroxidase activity
CYL17_05480	COG0745	RESPONSE REGULATOR receiver
CYL17_05485	COG5002	protein histidine kinase activity
CYL17_05510	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CYL17_05525	COG1285	pathogenesis
CYL17_05530	COG1316	TRANSCRIPTIONal
CYL17_05540	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CYL17_05555	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CYL17_05560	COG0371	Dehydrogenase
CYL17_05580	COG3594	Acyltransferase
CYL17_05585	COG1316	TRANSCRIPTIONal
CYL17_05620	COG1271	oxidase subunit
CYL17_05625	COG1294	oxidase, subunit
CYL17_05630	COG4988	ABC transporter
CYL17_05635	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CYL17_05650	COG2226	methyltransferase
CYL17_05670	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CYL17_05680	COG0778	Nitroreductase
CYL17_05680	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CYL17_05685	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CYL17_05720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CYL17_05725	COG2835	tetraacyldisaccharide 4'-kinase activity
CYL17_05755	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CYL17_05760	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CYL17_05790	COG0745	RESPONSE REGULATOR receiver
CYL17_05795	COG5002	protein histidine kinase activity
CYL17_05800	COG0823	Involved in the tonB-independent uptake of proteins
CYL17_05810	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CYL17_05815	COG2197	response regulator
CYL17_05825	COG0653	protein targeting
CYL17_05840	COG3509	depolymerase
CYL17_05845	COG2188	Transcriptional regulator
CYL17_05850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CYL17_05855	COG1472	Belongs to the glycosyl hydrolase 3 family
CYL17_05860	COG1011	Hydrolase
CYL17_05875	COG0546	phosphoglycolate phosphatase activity
CYL17_05880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CYL17_05885	COG2902	Dehydrogenase
CYL17_05895	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CYL17_05905	COG2884	Cell division ATP-binding protein ftsE
CYL17_05910	COG2177	Part of the ABC transporter FtsEX involved in
CYL17_05915	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CYL17_05935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CYL17_05950	COG1960	acyl-CoA dehydrogenase activity
CYL17_05965	COG4981	capsule polysaccharide biosynthetic process
CYL17_05975	COG0500	methyltransferase
CYL17_06000	COG0277	FAD linked oxidase domain protein
CYL17_06005	COG0300	oxidoreductase activity
CYL17_06045	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CYL17_06050	COG0686	Belongs to the AlaDH PNT family
CYL17_06060	COG0789	Transcriptional regulator
CYL17_06065	COG0405	Gamma-glutamyltransferase
CYL17_06085	COG2814	Major facilitator Superfamily
CYL17_06105	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CYL17_06150	COG1653	transport
CYL17_06155	COG2273	Hydrolase Family 16
CYL17_06185	COG2770	Histidine kinase
CYL17_06185	COG2208	phosphoserine phosphatase activity
CYL17_06195	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CYL17_06220	COG2271	Major facilitator Superfamily
CYL17_06235	COG0515	serine threonine protein kinase
CYL17_06235	COG2815	serine threonine protein kinase
CYL17_06270	COG0395	ABC-type sugar transport system, permease component
CYL17_06275	COG1175	transmembrane transport
CYL17_06280	COG1653	transport
CYL17_06285	COG1653	transport
CYL17_06295	COG1136	(ABC) transporter
CYL17_06305	COG0366	Alpha amylase catalytic
CYL17_06325	COG0019	diaminopimelate decarboxylase activity
CYL17_06330	COG0460	homoserine dehydrogenase
CYL17_06345	COG1215	transferase activity, transferring glycosyl groups
CYL17_06355	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CYL17_06360	COG0083	homoserine kinase activity
CYL17_06370	COG0254	rRNA binding
CYL17_06375	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CYL17_06380	COG2890	protein-(glutamine-N5) methyltransferase activity
CYL17_06410	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CYL17_06415	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CYL17_06420	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CYL17_06425	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CYL17_06430	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CYL17_06435	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CYL17_06440	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CYL17_06455	COG4152	abc transporter atp-binding protein
CYL17_06460	COG1668	transmembrane transport
CYL17_06465	COG4585	Histidine kinase
CYL17_06470	COG2197	response regulator
CYL17_06490	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CYL17_06505	COG0596	Alpha beta hydrolase
CYL17_06520	COG0183	Belongs to the thiolase family
CYL17_06555	COG1678	Uncharacterized ACR, COG1678
CYL17_06565	COG0477	Major facilitator Superfamily
CYL17_06595	COG1335	isochorismatase
CYL17_06605	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CYL17_06635	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CYL17_06640	COG1234	tRNA 3'-trailer cleavage
CYL17_06645	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CYL17_06650	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CYL17_06665	COG1309	transcriptional regulator
CYL17_06680	COG0577	efflux transmembrane transporter activity
CYL17_06680	COG1136	(ABC) transporter
CYL17_06685	COG0577	efflux transmembrane transporter activity
CYL17_06685	COG1136	(ABC) transporter
CYL17_06690	COG2197	response regulator
CYL17_06695	COG4585	Histidine kinase
CYL17_06740	COG0509	glycine decarboxylation via glycine cleavage system
CYL17_06745	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CYL17_06760	COG4221	oxidoreductase activity
CYL17_06770	COG1228	amidohydrolase
CYL17_06795	COG2018	Roadblock/LC7 domain
CYL17_06810	COG5002	protein histidine kinase activity
CYL17_06815	COG2018	Roadblock/LC7 domain
CYL17_06835	COG0228	four-way junction DNA binding
CYL17_06840	COG1837	Belongs to the UPF0109 family
CYL17_06845	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CYL17_06850	COG0336	Belongs to the RNA methyltransferase TrmD family
CYL17_06855	COG0335	large ribosomal subunit rRNA binding
CYL17_06860	COG0681	Belongs to the peptidase S26 family
CYL17_06870	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CYL17_06900	COG0792	nuclease activity
CYL17_06910	COG0052	Belongs to the universal ribosomal protein uS2 family
CYL17_06915	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CYL17_06920	COG0528	UMP kinase activity
CYL17_06925	COG0233	cytoplasmic translational termination
CYL17_06930	COG0575	Belongs to the CDS family
CYL17_06940	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CYL17_06950	COG3835	regulator
CYL17_06975	COG1012	belongs to the aldehyde dehydrogenase family
CYL17_06980	COG3842	ATPase activity
CYL17_06990	COG1176	ABC-type spermidine putrescine transport system, permease component I
CYL17_06995	COG1177	transmembrane transport
CYL17_07000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CYL17_07005	COG0640	Transcriptional regulator
CYL17_07020	COG1028	Short-chain dehydrogenase reductase Sdr
CYL17_07045	COG3469	chitinase activity
CYL17_07055	COG0628	permease
CYL17_07095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CYL17_07105	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CYL17_07130	COG1012	belongs to the aldehyde dehydrogenase family
CYL17_07150	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CYL17_07165	COG1309	transcriptional regulator
CYL17_07170	COG2409	Drug exporters of the RND superfamily
CYL17_07200	COG2188	Transcriptional regulator
CYL17_07220	COG0442	prolyl-tRNA aminoacylation
CYL17_07235	COG0779	Required for maturation of 30S ribosomal subunits
CYL17_07250	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CYL17_07260	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CYL17_07265	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CYL17_07270	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CYL17_07280	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CYL17_07285	COG1185	polyribonucleotide nucleotidyltransferase activity
CYL17_07290	COG0612	Peptidase, M16
CYL17_07295	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CYL17_07315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CYL17_07325	COG2188	Transcriptional regulator
CYL17_07330	COG2003	Belongs to the UPF0758 family
CYL17_07345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CYL17_07350	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CYL17_07360	COG4948	Mandelate Racemase Muconate Lactonizing
CYL17_07365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CYL17_07370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CYL17_07380	COG3866	Pectate lyase
CYL17_07390	COG0395	ABC-type sugar transport system, permease component
CYL17_07400	COG4948	Mandelate Racemase Muconate Lactonizing
CYL17_07405	COG1414	Transcriptional regulator
CYL17_07410	COG1674	ftsk spoiiie
CYL17_07420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CYL17_07430	COG1546	Belongs to the CinA family
CYL17_07430	COG1058	Belongs to the CinA family
CYL17_07435	COG1396	sequence-specific DNA binding
CYL17_07440	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CYL17_07450	COG1940	carbohydrate kinase activity
CYL17_07455	COG1472	Belongs to the glycosyl hydrolase 3 family
CYL17_07460	COG0395	ABC-type sugar transport system, permease component
CYL17_07465	COG1175	transmembrane transport
CYL17_07510	COG1201	RNA secondary structure unwinding
CYL17_07520	COG4152	abc transporter atp-binding protein
CYL17_07525	COG1668	transmembrane transport
CYL17_07535	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CYL17_07540	COG2137	regulation of response to DNA damage stimulus
CYL17_07545	COG1418	mRNA catabolic process
CYL17_07565	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CYL17_07570	COG1234	tRNA 3'-trailer cleavage
CYL17_07580	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CYL17_07585	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CYL17_07610	COG0247	lactate metabolic process
CYL17_07615	COG0277	FAD linked oxidase domain protein
CYL17_07620	COG0277	FAD linked oxidase domain protein
CYL17_07625	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CYL17_07635	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CYL17_07645	COG1596	polysaccharide export
CYL17_07645	COG1555	photosystem II stabilization
CYL17_07660	COG0268	Binds directly to 16S ribosomal RNA
CYL17_07665	COG0481	GTPase activity
CYL17_07670	COG2258	MOSC domain
CYL17_07685	COG1420	regulation of RNA biosynthetic process
CYL17_07690	COG0484	heat shock protein binding
CYL17_07710	COG0537	adenosine 5'-monophosphoramidase activity
CYL17_07720	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CYL17_07740	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CYL17_07750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CYL17_07765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CYL17_07770	COG1834	amidinotransferase
CYL17_07775	COG1522	sequence-specific DNA binding
CYL17_07780	COG0583	DNA-binding transcription factor activity
CYL17_07805	COG1381	Involved in DNA repair and RecF pathway recombination
CYL17_07810	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CYL17_07835	COG0423	glycine-tRNA ligase activity
CYL17_07845	COG0574	Belongs to the PEP-utilizing enzyme family
CYL17_07845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CYL17_07850	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CYL17_07860	COG0358	DNA primase activity
CYL17_07865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CYL17_07885	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CYL17_07890	COG2188	Transcriptional regulator
CYL17_07900	COG1129	ABC transporter
CYL17_07920	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CYL17_07925	COG1070	Carbohydrate kinase
CYL17_07955	COG1131	(ABC) transporter
CYL17_07960	COG2188	Transcriptional regulator
CYL17_07970	COG1309	transcriptional regulator
CYL17_07990	COG0730	response to heat
CYL17_07995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CYL17_08000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CYL17_08030	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CYL17_08040	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CYL17_08075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CYL17_08080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CYL17_08085	COG1120	ATPase activity
CYL17_08095	COG1028	Short-chain dehydrogenase reductase Sdr
CYL17_08120	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CYL17_08165	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CYL17_08175	COG0477	Major facilitator Superfamily
CYL17_08180	COG1309	transcriptional regulator
CYL17_08185	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CYL17_08185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CYL17_08195	COG2814	Major facilitator Superfamily
CYL17_08205	COG0174	glutamine synthetase
CYL17_08215	COG0505	Belongs to the CarA family
CYL17_08220	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CYL17_08240	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CYL17_08250	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CYL17_08255	COG0321	lipoyl(octanoyl) transferase activity
CYL17_08260	COG3340	Belongs to the peptidase S51 family
CYL17_08270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CYL17_08275	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CYL17_08280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CYL17_08295	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CYL17_08310	COG0667	Aldo Keto reductase
CYL17_08330	COG0501	Belongs to the peptidase M48B family
CYL17_08340	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CYL17_08350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CYL17_08365	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CYL17_08370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CYL17_08380	COG1376	ErfK ybiS ycfS ynhG family protein
CYL17_08385	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CYL17_08390	COG0723	plastoquinol--plastocyanin reductase activity
CYL17_08400	COG1845	cytochrome c oxidase, subunit III
CYL17_08410	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CYL17_08435	COG0791	NLP P60 protein
CYL17_08435	COG1388	LysM domain
CYL17_08460	COG1940	carbohydrate kinase activity
CYL17_08485	COG0204	Acyl-transferase
CYL17_08495	COG2040	homocysteine
CYL17_08530	COG4521	taurine ABC transporter
CYL17_08535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CYL17_08540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYL17_08550	COG0205	6-phosphofructokinase activity
CYL17_08555	COG0301	tRNA thio-modification
CYL17_08560	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CYL17_08565	COG3275	phosphorelay sensor kinase activity
CYL17_08570	COG3279	Response regulator of the LytR AlgR family
CYL17_08575	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CYL17_08605	COG2815	serine threonine protein kinase
CYL17_08605	COG0515	serine threonine protein kinase
CYL17_08610	COG2022	thiamine diphosphate biosynthetic process
CYL17_08620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CYL17_08620	COG2022	thiamine diphosphate biosynthetic process
CYL17_08635	COG0352	thiamine-phosphate diphosphorylase activity
CYL17_08640	COG0142	geranyltranstransferase activity
CYL17_08660	COG3409	Peptidoglycan-binding domain 1 protein
CYL17_08660	COG0860	N-Acetylmuramoyl-L-alanine amidase
CYL17_08675	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CYL17_08680	COG0540	Belongs to the ATCase OTCase family
CYL17_08685	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CYL17_08690	COG0505	Belongs to the CarA family
CYL17_08695	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CYL17_08700	COG0543	2 iron, 2 sulfur cluster binding
CYL17_08705	COG0167	dihydroorotate dehydrogenase activity
CYL17_08710	COG0284	orotidine-5'-phosphate decarboxylase activity
CYL17_08720	COG0194	GDP metabolic process
CYL17_08725	COG1758	RNA polymerase activity
CYL17_08735	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CYL17_08755	COG0242	peptide deformylase activity
CYL17_08760	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CYL17_08770	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CYL17_08775	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CYL17_08775	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CYL17_08785	COG3201	nicotinamide mononucleotide transporter
CYL17_08790	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CYL17_08790	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CYL17_08795	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CYL17_08810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CYL17_08815	COG1116	anion transmembrane transporter activity
CYL17_08820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CYL17_08835	COG0542	response to heat
CYL17_08860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYL17_08870	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CYL17_08875	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CYL17_08885	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CYL17_08895	COG1305	Transglutaminase-like
CYL17_08905	COG0714	Associated with various cellular activities
CYL17_08910	COG2001	Belongs to the MraZ family
CYL17_08915	COG0275	rRNA processing
CYL17_08925	COG0768	penicillin binding
CYL17_08930	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CYL17_08940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CYL17_08945	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CYL17_08955	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CYL17_08960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CYL17_08965	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CYL17_08970	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CYL17_08980	COG1799	cell septum assembly
CYL17_09000	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CYL17_09005	COG1872	DUF167
CYL17_09015	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CYL17_09030	COG0210	DNA helicase
CYL17_09035	COG0515	serine threonine protein kinase
CYL17_09045	COG0587	DNA-directed DNA polymerase activity
CYL17_09055	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CYL17_09065	COG0154	amidase activity
CYL17_09070	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CYL17_09075	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CYL17_09085	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CYL17_09090	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CYL17_09095	COG0131	Imidazoleglycerol-phosphate dehydratase
CYL17_09100	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CYL17_09105	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CYL17_09110	COG0251	oxidation-reduction process
CYL17_09115	COG0107	imidazoleglycerol-phosphate synthase activity
CYL17_09130	COG1132	(ABC) transporter
CYL17_09135	COG1132	(ABC) transporter
CYL17_09140	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CYL17_09160	COG0134	indole-3-glycerol-phosphate synthase activity
CYL17_09165	COG0133	tryptophan synthase activity
CYL17_09170	COG0159	tryptophan synthase activity
CYL17_09185	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CYL17_09195	COG0069	glutamate synthase activity
CYL17_09195	COG0067	glutamate synthase
CYL17_09195	COG0070	glutamate synthase
CYL17_09225	COG0559	Belongs to the binding-protein-dependent transport system permease family
CYL17_09230	COG0411	ABC transporter
CYL17_09255	COG0683	leucine binding
CYL17_09280	COG2050	protein possibly involved in aromatic compounds catabolism
CYL17_09295	COG0539	negative regulation of cytoplasmic translation
CYL17_09305	COG0237	dephospho-CoA kinase activity
CYL17_09330	COG0556	nucleotide-excision repair
CYL17_09335	COG0110	maltose O-acetyltransferase activity
CYL17_09340	COG0504	CTP synthase activity
CYL17_09360	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CYL17_09365	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CYL17_09385	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CYL17_09390	COG1160	GTP binding
CYL17_09395	COG0477	Major facilitator Superfamily
CYL17_09450	COG1012	belongs to the aldehyde dehydrogenase family
CYL17_09455	COG0506	proline dehydrogenase activity
CYL17_09465	COG0438	transferase activity, transferring glycosyl groups
CYL17_09475	COG1252	NADH dehydrogenase
CYL17_09530	COG2188	Transcriptional regulator
CYL17_09560	COG3693	PFAM glycoside hydrolase, family 10
CYL17_09600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CYL17_09605	COG1518	maintenance of DNA repeat elements
CYL17_09620	COG1857	crispr-associated protein
CYL17_09645	COG0443	Heat shock 70 kDa protein
CYL17_09665	COG0515	serine threonine protein kinase
CYL17_09695	COG0531	amino acid
CYL17_09705	COG0804	urea catabolic process
CYL17_09710	COG0831	urea catabolic process
CYL17_09710	COG0832	Belongs to the urease beta subunit family
CYL17_09715	COG1609	Transcriptional regulator
CYL17_09725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CYL17_09730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CYL17_09735	COG1116	anion transmembrane transporter activity
CYL17_09740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYL17_09745	COG3693	PFAM glycoside hydrolase, family 10
CYL17_09755	COG1653	transport
CYL17_09760	COG0395	ABC-type sugar transport system, permease component
CYL17_09765	COG4209	transmembrane transport
CYL17_09805	COG1966	Carbon starvation protein
CYL17_09820	COG2323	membrane
CYL17_09840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CYL17_09875	COG1028	Short-chain dehydrogenase reductase Sdr
CYL17_09885	COG1960	acyl-CoA dehydrogenase activity
CYL17_09890	COG3842	ATPase activity
CYL17_09895	COG1177	transmembrane transport
CYL17_09900	COG1176	ABC-type spermidine putrescine transport system, permease component I
CYL17_09920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYL17_09925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYL17_09930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYL17_09935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYL17_09940	COG2855	membrane
CYL17_09960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CYL17_09975	COG0318	PFAM AMP-dependent synthetase and ligase
CYL17_09990	COG0431	NADPH-dependent FMN reductase
CYL17_10000	COG1028	Short-chain dehydrogenase reductase Sdr
CYL17_10010	COG1028	Short-chain dehydrogenase reductase Sdr
CYL17_10025	COG0477	Major facilitator Superfamily
CYL17_10050	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CYL17_10050	COG1703	isobutyryl-CoA mutase activity
CYL17_10050	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CYL17_10055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CYL17_10060	COG2197	response regulator
CYL17_10065	COG1120	ATPase activity
CYL17_10070	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CYL17_10075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CYL17_10100	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CYL17_10105	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CYL17_10105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CYL17_10125	COG1960	acyl-CoA dehydrogenase activity
CYL17_10130	COG1309	transcriptional regulator
CYL17_10150	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CYL17_10210	COG2217	Heavy metal translocating P-type atpase
CYL17_10215	COG4109	DRTGG domain
CYL17_10230	COG2132	Multicopper oxidase
CYL17_10255	COG2205	protein histidine kinase activity
CYL17_10270	COG2847	Copper chaperone PCu(A)C
CYL17_10285	COG1472	Belongs to the glycosyl hydrolase 3 family
CYL17_10290	COG1737	Transcriptional regulator
CYL17_10305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CYL17_10315	COG4608	Belongs to the ABC transporter superfamily
CYL17_10325	COG3876	Protein conserved in bacteria
CYL17_10330	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CYL17_10335	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CYL17_10370	COG1515	deoxyribonuclease V activity
CYL17_10375	COG0435	Glutathione S-transferase
CYL17_10415	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CYL17_10420	COG2183	response to ionizing radiation
CYL17_10440	COG0772	Belongs to the SEDS family
CYL17_10445	COG0768	penicillin binding
CYL17_10450	COG1792	Involved in formation and maintenance of cell shape
CYL17_10480	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CYL17_10485	COG1716	ATPase activity
CYL17_10505	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CYL17_10505	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CYL17_10555	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CYL17_10560	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CYL17_10570	COG2188	Transcriptional regulator
CYL17_10590	COG1132	(ABC) transporter
CYL17_10595	COG4988	ABC transporter
CYL17_10600	COG1739	Uncharacterized protein family UPF0029
CYL17_10605	COG1169	isochorismate synthase
CYL17_10620	COG2197	response regulator
CYL17_10625	COG4585	Histidine kinase
CYL17_10635	COG1131	(ABC) transporter
CYL17_10640	COG0438	transferase activity, transferring glycosyl groups
CYL17_10665	COG2261	transglycosylase associated protein
CYL17_10675	COG0697	spore germination
CYL17_10720	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CYL17_10725	COG1012	belongs to the aldehyde dehydrogenase family
CYL17_10730	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CYL17_10745	COG1960	acyl-CoA dehydrogenase activity
CYL17_10750	COG0492	ferredoxin-NADP+ reductase activity
CYL17_10765	COG0475	glutathione-regulated potassium exporter activity
CYL17_10790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CYL17_10795	COG1376	ErfK ybiS ycfS ynhG family protein
CYL17_10815	COG2076	Multidrug Resistance protein
CYL17_10820	COG1309	transcriptional regulator
CYL17_10825	COG0842	Transport permease protein
CYL17_10835	COG1131	(ABC) transporter
CYL17_10845	COG3290	protein histidine kinase activity
CYL17_10850	COG4565	transcriptional regulatory protein
CYL17_10860	COG2197	response regulator
CYL17_10875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CYL17_10880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CYL17_10900	COG4974	Belongs to the 'phage' integrase family
CYL17_10905	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CYL17_10915	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CYL17_10920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CYL17_10940	COG1280	lysine exporter protein (LysE YggA)
CYL17_10950	COG2223	nitrite transmembrane transporter activity
CYL17_10965	COG0714	Associated with various cellular activities
CYL17_10980	COG2813	Specifically methylates the guanine in position
CYL17_10985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CYL17_10990	COG0584	glycerophosphoryl diester phosphodiesterase
CYL17_11005	COG0583	DNA-binding transcription factor activity
CYL17_11010	COG1960	acyl-CoA dehydrogenase activity
CYL17_11025	COG0463	Glycosyl transferase, family 2
CYL17_11055	COG1522	sequence-specific DNA binding
CYL17_11060	COG1960	acyl-CoA dehydrogenase activity
CYL17_11080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CYL17_11095	COG0805	protein transport
CYL17_11100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CYL17_11125	COG0545	Peptidyl-prolyl cis-trans isomerase
CYL17_11130	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CYL17_11140	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CYL17_11145	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CYL17_11160	COG4122	O-methyltransferase activity
CYL17_11170	COG1222	aaa ATPase
CYL17_11180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CYL17_11190	COG0517	IMP dehydrogenase activity
CYL17_11190	COG1994	Peptidase M50
CYL17_11200	COG4585	Histidine kinase
CYL17_11205	COG2197	response regulator
CYL17_11210	COG4608	Belongs to the ABC transporter superfamily
CYL17_11215	COG0444	Belongs to the ABC transporter superfamily
CYL17_11230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CYL17_11240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CYL17_11245	COG0646	methionine synthase
CYL17_11245	COG1410	methionine synthase
CYL17_11255	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CYL17_11275	COG0543	2 iron, 2 sulfur cluster binding
CYL17_11290	COG0463	Glycosyl transferase, family 2
CYL17_11380	COG0366	Alpha amylase catalytic
CYL17_11385	COG3833	ABC-type maltose transport systems, permease component
CYL17_11400	COG3842	ATPase activity
CYL17_11410	COG2205	protein histidine kinase activity
CYL17_11415	COG3119	arylsulfatase activity
CYL17_11425	COG1175	transmembrane transport
CYL17_11430	COG0395	ABC-type sugar transport system, permease component
CYL17_11435	COG2723	6-phospho-beta-galactosidase activity
CYL17_11445	COG2723	6-phospho-beta-galactosidase activity
CYL17_11450	COG2017	converts alpha-aldose to the beta-anomer
CYL17_11455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CYL17_11460	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CYL17_11470	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CYL17_11475	COG0589	response to stress
CYL17_11485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CYL17_11500	COG2011	ABC-type metal ion transport system permease component
CYL17_11505	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CYL17_11515	COG3540	Alkaline phosphatase
CYL17_11535	COG0672	)-iron permease
CYL17_11545	COG2837	iron assimilation
CYL17_11575	COG4133	protoheme IX ABC transporter activity
CYL17_11625	COG0215	cysteine-tRNA ligase activity
CYL17_11650	COG1968	undecaprenyl-diphosphatase activity
CYL17_11655	COG0667	Aldo Keto reductase
CYL17_11665	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CYL17_11670	COG1028	Short-chain dehydrogenase reductase Sdr
CYL17_11685	COG3360	Dodecin
CYL17_11695	COG0746	molybdenum cofactor guanylyltransferase activity
CYL17_11700	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CYL17_11735	COG3104	oligopeptide transport
CYL17_11740	COG3387	PFAM Glycoside hydrolase 15-related
CYL17_11745	COG1619	proteins homologs of microcin C7 resistance protein MccF
CYL17_11755	COG1132	(ABC) transporter
CYL17_11770	COG0488	(ABC) transporter
CYL17_11780	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CYL17_11785	COG0140	phosphoribosyl-ATP diphosphatase activity
CYL17_11790	COG3458	cephalosporin-C deacetylase activity
CYL17_11795	COG2151	metal-sulfur cluster biosynthetic enzyme
CYL17_11800	COG0822	iron-sulfur transferase activity
CYL17_11805	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CYL17_11810	COG0396	ATPase activity
CYL17_11815	COG2146	nitrite reductase [NAD(P)H] activity
CYL17_11820	COG0719	Fe-S assembly protein
CYL17_11835	COG1131	(ABC) transporter
CYL17_11845	COG5006	permease, DMT superfamily
CYL17_11860	COG0109	protoheme IX farnesyltransferase activity
CYL17_11870	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CYL17_11875	COG0166	Belongs to the GPI family
CYL17_11890	COG0363	glucosamine-6-phosphate deaminase activity
CYL17_11895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CYL17_11895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CYL17_11900	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CYL17_11915	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CYL17_11920	COG0149	triose-phosphate isomerase activity
CYL17_11925	COG0126	phosphoglycerate kinase activity
CYL17_11930	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CYL17_11935	COG1481	regulation of sporulation
CYL17_11945	COG1660	Displays ATPase and GTPase activities
CYL17_11950	COG0322	excinuclease ABC activity
CYL17_11960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CYL17_11970	COG4948	Mandelate Racemase Muconate Lactonizing
CYL17_11985	COG0688	phosphatidylethanolamine metabolic process
CYL17_11995	COG0297	glycogen (starch) synthase activity
CYL17_12020	COG0497	DNA recombination
CYL17_12025	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CYL17_12045	COG0647	UMP catabolic process
CYL17_12070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CYL17_12075	COG3401	FG-GAP repeat protein
CYL17_12080	COG2094	Belongs to the DNA glycosylase MPG family
CYL17_12085	COG0165	Argininosuccinate lyase
CYL17_12090	COG0137	argininosuccinate synthase activity
CYL17_12095	COG1438	arginine binding
CYL17_12100	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CYL17_12105	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CYL17_12110	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CYL17_12115	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CYL17_12120	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CYL17_12125	COG0318	PFAM AMP-dependent synthetase and ligase
CYL17_12145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CYL17_12145	COG0072	phenylalanine-tRNA ligase activity
CYL17_12150	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CYL17_12155	COG5002	protein histidine kinase activity
CYL17_12160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CYL17_12165	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CYL17_12175	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CYL17_12180	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CYL17_12185	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CYL17_12195	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CYL17_12200	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CYL17_12225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CYL17_12230	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CYL17_12235	COG0124	histidyl-tRNA synthetase
CYL17_12245	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CYL17_12250	COG1196	nuclear chromosome segregation
CYL17_12255	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CYL17_12260	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CYL17_12265	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CYL17_12270	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CYL17_12275	COG1862	Preprotein translocase
CYL17_12280	COG2255	four-way junction helicase activity
CYL17_12285	COG0632	four-way junction helicase activity
CYL17_12290	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CYL17_12295	COG0217	transcriptional regulatory protein
CYL17_12300	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CYL17_12310	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CYL17_12325	COG0438	transferase activity, transferring glycosyl groups
CYL17_12330	COG1560	Kdo2-lipid A biosynthetic process
CYL17_12335	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CYL17_12345	COG1649	PFAM Uncharacterised BCR, COG1649
CYL17_12355	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CYL17_12360	COG0667	Aldo Keto reductase
CYL17_12380	COG0318	PFAM AMP-dependent synthetase and ligase
CYL17_12385	COG2197	response regulator
CYL17_12395	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CYL17_12405	COG1733	regulation of RNA biosynthetic process
CYL17_12410	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CYL17_12415	COG1024	Enoyl-CoA hydratase
CYL17_12420	COG1960	acyl-CoA dehydrogenase activity
CYL17_12425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CYL17_12450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CYL17_12455	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CYL17_12455	COG0512	Glutamine amidotransferase of anthranilate synthase
CYL17_12460	COG0583	DNA-binding transcription factor activity
CYL17_12470	COG2986	histidine ammonia-lyase
CYL17_12495	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CYL17_12500	COG0477	Major facilitator Superfamily
CYL17_12505	COG1309	transcriptional regulator
CYL17_12520	COG3851	Histidine kinase
CYL17_12545	COG2124	cytochrome p450
CYL17_12555	COG0297	glycogen (starch) synthase activity
CYL17_12560	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CYL17_12570	COG1024	Enoyl-CoA hydratase
CYL17_12580	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CYL17_12610	COG0243	molybdopterin cofactor binding
CYL17_12625	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CYL17_12630	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CYL17_12630	COG1796	DNA polymerase
CYL17_12645	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CYL17_12655	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CYL17_12665	COG3279	Response regulator of the LytR AlgR family
CYL17_12670	COG3275	phosphorelay sensor kinase activity
CYL17_12705	COG1597	lipid kinase activity
CYL17_12715	COG0277	FAD linked oxidase domain protein
CYL17_12720	COG1024	Enoyl-CoA hydratase
CYL17_12735	COG2313	pseudouridylate synthase activity
CYL17_12755	COG1960	acyl-CoA dehydrogenase activity
CYL17_12770	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CYL17_12780	COG0022	dehydrogenase e1 component
CYL17_12830	COG0419	ATPase involved in DNA repair
CYL17_12835	COG0420	3'-5' exonuclease activity
CYL17_12845	COG1316	TRANSCRIPTIONal
CYL17_12850	COG4948	Mandelate Racemase Muconate Lactonizing
CYL17_12855	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CYL17_12865	COG0714	Associated with various cellular activities
CYL17_12880	COG1012	belongs to the aldehyde dehydrogenase family
CYL17_12890	COG1741	Belongs to the pirin family
CYL17_12915	COG3842	ATPase activity
CYL17_12960	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CYL17_12965	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CYL17_12970	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CYL17_12975	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CYL17_12995	COG0549	Belongs to the carbamate kinase family
CYL17_13000	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CYL17_13005	COG0450	alkyl hydroperoxide reductase
CYL17_13020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CYL17_13075	COG2233	PERMEase
CYL17_13090	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CYL17_13095	COG1304	FMN binding
CYL17_13110	COG0277	FAD linked oxidase domain protein
CYL17_13130	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CYL17_13135	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CYL17_13145	COG0175	sulfate reduction
CYL17_13170	COG1960	acyl-CoA dehydrogenase activity
CYL17_13195	COG1793	dna ligase
CYL17_13210	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CYL17_13220	COG3253	May function as heme-dependent peroxidase
CYL17_13225	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CYL17_13235	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CYL17_13245	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CYL17_13250	COG0183	Belongs to the thiolase family
CYL17_13260	COG0531	amino acid
CYL17_13265	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CYL17_13280	COG4214	carbohydrate transport
CYL17_13290	COG4213	ABC transporter substrate-binding protein
CYL17_13300	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CYL17_13335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CYL17_13340	COG0531	amino acid
CYL17_13345	COG0569	domain protein
CYL17_13370	COG0756	dUTP diphosphatase activity
CYL17_13380	COG0525	valine-tRNA ligase activity
CYL17_13390	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CYL17_13405	COG2205	protein histidine kinase activity
CYL17_13410	COG0745	RESPONSE REGULATOR receiver
CYL17_13425	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CYL17_13430	COG0739	heme binding
CYL17_13465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CYL17_13490	COG1579	Zn-ribbon protein possibly nucleic acid-binding
CYL17_13495	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CYL17_13500	COG2205	protein histidine kinase activity
CYL17_13515	COG0300	oxidoreductase activity
CYL17_13525	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CYL17_13530	COG1609	Transcriptional regulator
CYL17_13575	COG1643	Atp-dependent helicase
CYL17_13580	COG0745	RESPONSE REGULATOR receiver
CYL17_13620	COG1404	Belongs to the peptidase S8 family
CYL17_13640	COG3173	Aminoglycoside phosphotransferase
CYL17_13660	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CYL17_13725	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CYL17_13740	COG0754	glutathionylspermidine amidase activity
CYL17_13745	COG3766	membrane
CYL17_13780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CYL17_13785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CYL17_13855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CYL17_13865	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CYL17_13900	COG0187	DNA topoisomerase II activity
CYL17_13915	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CYL17_13915	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CYL17_13920	COG5001	Diguanylate cyclase
CYL17_13930	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CYL17_13950	COG1609	Transcriptional regulator
CYL17_13955	COG1472	Belongs to the glycosyl hydrolase 3 family
CYL17_13960	COG1940	carbohydrate kinase activity
CYL17_13980	COG0515	serine threonine protein kinase
CYL17_13985	COG1472	Belongs to the glycosyl hydrolase 3 family
CYL17_13990	COG0395	ABC-type sugar transport system, permease component
CYL17_14005	COG1501	Belongs to the glycosyl hydrolase 31 family
CYL17_14040	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CYL17_14045	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CYL17_14050	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CYL17_14055	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CYL17_14060	COG0495	leucyl-tRNA aminoacylation
CYL17_14075	COG0318	PFAM AMP-dependent synthetase and ligase
CYL17_14080	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CYL17_14130	COG0424	maF-like protein
CYL17_14145	COG1492	cobalamin metabolic process
CYL17_14155	COG1028	Short-chain dehydrogenase reductase Sdr
CYL17_14185	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CYL17_14190	COG0501	Belongs to the peptidase M48B family
CYL17_14200	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CYL17_14205	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CYL17_14210	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CYL17_14215	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CYL17_14220	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CYL17_14225	COG1530	ribonuclease E activity
CYL17_14240	COG0772	Belongs to the SEDS family
CYL17_14245	COG0768	penicillin binding
CYL17_14260	COG1077	Cell shape determining protein MreB Mrl
CYL17_14265	COG0105	UTP biosynthetic process
CYL17_14280	COG0285	dihydrofolate synthase activity
CYL17_14290	COG0525	valine-tRNA ligase activity
CYL17_14295	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CYL17_14300	COG0740	serine-type endopeptidase activity
CYL17_14305	COG0740	serine-type endopeptidase activity
CYL17_14310	COG0544	peptidyl-prolyl cis-trans isomerase activity
CYL17_14330	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CYL17_14365	COG0318	PFAM AMP-dependent synthetase and ligase
CYL17_14375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CYL17_14400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYL17_14410	COG1028	Short-chain dehydrogenase reductase Sdr
CYL17_14430	COG0750	zinc metalloprotease
CYL17_14450	COG0242	peptide deformylase activity
CYL17_14470	COG0154	amidase activity
CYL17_14480	COG0129	dihydroxy-acid dehydratase activity
CYL17_14505	COG1505	serine-type exopeptidase activity
CYL17_14535	COG0668	transmembrane transport
CYL17_14585	COG0629	single-stranded DNA binding
CYL17_14600	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CYL17_14600	COG1648	precorrin-2 dehydrogenase activity
CYL17_14605	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CYL17_14630	COG0583	DNA-binding transcription factor activity
CYL17_14645	COG0587	DNA-directed DNA polymerase activity
CYL17_14660	COG3848	Pyruvate phosphate dikinase
CYL17_14660	COG0574	Belongs to the PEP-utilizing enzyme family
CYL17_14675	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CYL17_14700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CYL17_14705	COG1609	Transcriptional regulator
CYL17_14720	COG1172	Belongs to the binding-protein-dependent transport system permease family
CYL17_14740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CYL17_14745	COG4266	Belongs to the allantoicase family
CYL17_14750	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CYL17_14755	COG1929	Belongs to the glycerate kinase type-1 family
CYL17_14805	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CYL17_14810	COG1984	allophanate hydrolase subunit 2
CYL17_14820	COG1760	l-serine dehydratase
CYL17_14825	COG2723	6-phospho-beta-galactosidase activity
CYL17_14830	COG1012	belongs to the aldehyde dehydrogenase family
CYL17_14835	COG0028	Belongs to the TPP enzyme family
CYL17_14840	COG0477	Major facilitator Superfamily
CYL17_14850	COG0804	urea catabolic process
CYL17_14855	COG0831	urea catabolic process
CYL17_14855	COG0832	Belongs to the urease beta subunit family
CYL17_14875	COG3608	succinylglutamate desuccinylase aspartoacylase
CYL17_14875	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CYL17_14885	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CYL17_14895	COG0375	protein maturation
CYL17_14920	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CYL17_14935	COG1595	DNA-templated transcription, initiation
CYL17_14940	COG2852	Protein conserved in bacteria
CYL17_14965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CYL17_14980	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CYL17_14980	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CYL17_14985	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CYL17_14990	COG0297	glycogen (starch) synthase activity
CYL17_14995	COG0859	PFAM glycosyl transferase family 9
CYL17_15005	COG2192	nodulation
CYL17_15010	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CYL17_15030	COG0121	glutamine amidotransferase
CYL17_15035	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CYL17_15040	COG3572	ergothioneine biosynthetic process
CYL17_15055	COG0640	Transcriptional regulator
CYL17_15065	COG5297	Belongs to the glycosyl hydrolase family 6
CYL17_15085	COG0039	L-malate dehydrogenase activity
CYL17_15105	COG0215	cysteine-tRNA ligase activity
CYL17_15115	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CYL17_15125	COG3903	Transcriptional regulator
CYL17_15125	COG3629	intracellular signal transduction
CYL17_15160	COG0726	polysaccharide deacetylase
CYL17_15160	COG1649	PFAM Uncharacterised BCR, COG1649
CYL17_15180	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CYL17_15190	COG2197	response regulator
CYL17_15220	COG0477	Major facilitator Superfamily
CYL17_15235	COG0725	ABC transporter, periplasmic molybdate-binding protein
CYL17_15245	COG0783	Belongs to the Dps family
CYL17_15275	COG1960	acyl-CoA dehydrogenase activity
CYL17_15280	COG1960	acyl-CoA dehydrogenase activity
CYL17_15285	COG1960	acyl-CoA dehydrogenase activity
CYL17_15305	COG0653	protein targeting
CYL17_15320	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CYL17_15345	COG0516	GMP reductase activity
CYL17_15345	COG0517	IMP dehydrogenase activity
CYL17_15350	COG2239	Acts as a magnesium transporter
CYL17_15360	COG1653	transport
CYL17_15370	COG0395	ABC-type sugar transport system, permease component
CYL17_15420	COG0210	DNA helicase
CYL17_15425	COG1111	helicase
CYL17_15425	COG1205	dead DEAH box helicase
CYL17_15430	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CYL17_15435	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CYL17_15440	COG2814	Major facilitator Superfamily
CYL17_15450	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CYL17_15515	COG1294	oxidase, subunit
CYL17_15520	COG1271	oxidase subunit
CYL17_15540	COG2130	NADP-dependent
CYL17_15545	COG1950	PFAM Membrane protein of
CYL17_15555	COG2807	transmembrane transport
CYL17_15570	COG1414	Transcriptional regulator
CYL17_15575	COG0667	Aldo Keto reductase
CYL17_15600	COG1217	gtp-binding protein TYPA
CYL17_15610	COG0433	COG0433 Predicted ATPase
CYL17_15615	COG0726	polysaccharide deacetylase
CYL17_15620	COG1476	TRANSCRIPTIONal
CYL17_15630	COG1595	DNA-templated transcription, initiation
CYL17_15645	COG1196	nuclear chromosome segregation
CYL17_15655	COG1254	Belongs to the acylphosphatase family
CYL17_15660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CYL17_15665	COG0571	ribonuclease III activity
CYL17_15670	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CYL17_15680	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CYL17_15685	COG0742	ribosomal rna small subunit methyltransferase
CYL17_15695	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CYL17_15700	COG0351	phosphomethylpyrimidine kinase
CYL17_15725	COG1181	Belongs to the D-alanine--D-alanine ligase family
CYL17_15730	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CYL17_15740	COG1920	GTP binding
CYL17_15760	COG0776	regulation of translation
CYL17_15765	COG0066	3-isopropylmalate dehydratase activity
CYL17_15770	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CYL17_15775	COG1414	Transcriptional regulator
CYL17_15800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CYL17_15805	COG0179	Fumarylacetoacetate (FAA) hydrolase
CYL17_15820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CYL17_15830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CYL17_15835	COG0473	3-isopropylmalate dehydrogenase activity
CYL17_15840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CYL17_15850	COG2211	Major facilitator Superfamily
CYL17_15855	COG2340	Cysteine-rich secretory protein family
CYL17_15865	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CYL17_15870	COG0440	acetolactate synthase activity
CYL17_15880	COG3300	MHYT domain
CYL17_15880	COG5001	Diguanylate cyclase
CYL17_15885	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CYL17_15890	COG2133	pyrroloquinoline quinone binding
CYL17_15900	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CYL17_15905	COG0154	amidase activity
CYL17_15910	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CYL17_15930	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CYL17_15935	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CYL17_15945	COG3485	protocatechuate 3,4-dioxygenase
CYL17_15950	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CYL17_15955	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CYL17_15960	COG1414	Transcriptional regulator
CYL17_15965	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CYL17_15975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CYL17_15980	COG0482	sulfurtransferase activity
CYL17_15995	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CYL17_16010	COG0515	serine threonine protein kinase
CYL17_16010	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CYL17_16025	COG2362	D-Aminopeptidase
CYL17_16040	COG1024	Enoyl-CoA hydratase
CYL17_16045	COG0438	transferase activity, transferring glycosyl groups
CYL17_16055	COG0058	SHG alpha-glucan phosphorylase activity
CYL17_16060	COG0366	Alpha amylase catalytic
CYL17_16070	COG3281	Trehalose synthase
CYL17_16075	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CYL17_16085	COG0616	signal peptide processing
CYL17_16110	COG0318	PFAM AMP-dependent synthetase and ligase
CYL17_16130	COG1309	transcriptional regulator
CYL17_16140	COG0438	transferase activity, transferring glycosyl groups
CYL17_16145	COG2226	methyltransferase
CYL17_16180	COG0673	inositol 2-dehydrogenase activity
CYL17_16185	COG4213	ABC transporter substrate-binding protein
CYL17_16190	COG1172	Belongs to the binding-protein-dependent transport system permease family
CYL17_16195	COG1129	ABC transporter
CYL17_16200	COG1940	carbohydrate kinase activity
CYL17_16225	COG0567	Dehydrogenase, E1 component
CYL17_16225	COG0508	dehydrogenase complex catalyzes the overall conversion of
CYL17_16235	COG0604	alcohol dehydrogenase
CYL17_16250	COG0488	(ABC) transporter
CYL17_16290	COG2172	sigma factor antagonist activity
CYL17_16305	COG1597	lipid kinase activity
CYL17_16320	COG2188	Transcriptional regulator
CYL17_16335	COG0515	serine threonine protein kinase
CYL17_16345	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CYL17_16370	COG1595	DNA-templated transcription, initiation
CYL17_16385	COG2135	peptidase activity
CYL17_16390	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CYL17_16400	COG0483	inositol monophosphate 1-phosphatase activity
CYL17_16415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CYL17_16430	COG0581	inorganic phosphate transmembrane transporter activity
CYL17_16435	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CYL17_16450	COG0747	negative chemotaxis
CYL17_16490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CYL17_16495	COG0601	transmembrane transport
CYL17_16500	COG0747	negative chemotaxis
CYL17_16530	COG1615	UPF0182 protein
CYL17_16535	COG3480	Lon protease (S16) C-terminal proteolytic domain
CYL17_16575	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CYL17_16595	COG1946	Acyl-CoA thioesterase
CYL17_16625	COG4264	IucA IucC family
CYL17_16635	COG0019	diaminopimelate decarboxylase activity
CYL17_16645	COG0210	DNA helicase
CYL17_16650	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CYL17_16675	COG1404	Belongs to the peptidase S8 family
CYL17_16720	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CYL17_16725	COG3285	dna ligase
CYL17_16725	COG1793	dna ligase
CYL17_16750	COG0513	Belongs to the DEAD box helicase family
CYL17_16775	COG0494	nUDIX hydrolase
CYL17_16785	COG1266	CAAX protease self-immunity
CYL17_16790	COG2301	Belongs to the HpcH HpaI aldolase family
CYL17_16795	COG1268	BioY protein
CYL17_16815	COG2239	Acts as a magnesium transporter
CYL17_16830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CYL17_16850	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CYL17_16860	COG1024	Enoyl-CoA hydratase
CYL17_16865	COG0519	Catalyzes the synthesis of GMP from XMP
CYL17_16880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CYL17_16890	COG1611	Belongs to the LOG family
CYL17_16920	COG4106	trans-aconitate 2-methyltransferase activity
CYL17_16930	COG0210	DNA helicase
CYL17_16940	COG0215	cysteine-tRNA ligase activity
CYL17_16950	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CYL17_16965	COG0542	response to heat
CYL17_16980	COG1053	succinate dehydrogenase
CYL17_16995	COG0494	nUDIX hydrolase
CYL17_17000	COG1388	LysM domain
CYL17_17000	COG0791	NLP P60 protein
CYL17_17035	COG0012	GTP binding
CYL17_17040	COG1322	Protein conserved in bacteria
CYL17_17050	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CYL17_17060	COG1570	exodeoxyribonuclease VII activity
CYL17_17065	COG0367	asparagine synthase
CYL17_17070	COG1722	exodeoxyribonuclease VII activity
CYL17_17100	COG3962	Belongs to the TPP enzyme family
CYL17_17105	COG3718	enzyme involved in inositol metabolism
CYL17_17115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CYL17_17125	COG0673	inositol 2-dehydrogenase activity
CYL17_17140	COG0515	serine threonine protein kinase
CYL17_17145	COG0515	serine threonine protein kinase
CYL17_17145	COG2815	serine threonine protein kinase
CYL17_17150	COG0114	fumarate hydratase activity
CYL17_17160	COG1215	transferase activity, transferring glycosyl groups
CYL17_17170	COG0745	RESPONSE REGULATOR receiver
CYL17_17175	COG2205	protein histidine kinase activity
CYL17_17185	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CYL17_17190	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CYL17_17195	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CYL17_17205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CYL17_17215	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CYL17_17255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CYL17_17265	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CYL17_17275	COG0180	Tryptophanyl-tRNA synthetase
CYL17_17280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CYL17_17290	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CYL17_17315	COG2755	lipolytic protein G-D-S-L family
CYL17_17325	COG0183	Belongs to the thiolase family
CYL17_17345	COG2205	protein histidine kinase activity
CYL17_17350	COG0477	Major facilitator Superfamily
CYL17_17385	COG0148	phosphopyruvate hydratase activity
CYL17_17410	COG0529	Catalyzes the synthesis of activated sulfate
CYL17_17430	COG0515	serine threonine protein kinase
CYL17_17430	COG2815	serine threonine protein kinase
CYL17_17470	COG1218	3'(2'),5'-bisphosphate nucleotidase
CYL17_17475	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CYL17_17480	COG0193	aminoacyl-tRNA hydrolase activity
CYL17_17485	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CYL17_17490	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CYL17_17495	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CYL17_17510	COG1309	transcriptional regulator
CYL17_17515	COG4106	trans-aconitate 2-methyltransferase activity
CYL17_17560	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CYL17_17565	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CYL17_17570	COG0084	hydrolase, TatD family'
CYL17_17580	COG2132	Multicopper oxidase
CYL17_17590	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CYL17_17650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CYL17_17655	COG0521	Mo-molybdopterin cofactor biosynthetic process
CYL17_17660	COG0315	cyclic pyranopterin monophosphate synthase activity
CYL17_17670	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CYL17_17675	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CYL17_17680	COG3263	regulation of cellular component size
CYL17_17690	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CYL17_17725	COG1252	NADH dehydrogenase
CYL17_17730	COG1595	DNA-templated transcription, initiation
CYL17_17735	COG1309	transcriptional regulator
CYL17_17740	COG1131	(ABC) transporter
CYL17_17745	COG3559	Exporter of polyketide antibiotics
CYL17_17760	COG2030	dehydratase
CYL17_17765	COG1960	acyl-CoA dehydrogenase activity
CYL17_17770	COG1024	Enoyl-CoA hydratase
CYL17_17775	COG0154	amidase activity
CYL17_17785	COG2267	carboxylic ester hydrolase activity
CYL17_17790	COG0318	PFAM AMP-dependent synthetase and ligase
CYL17_17820	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CYL17_17825	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CYL17_17830	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CYL17_17835	COG0375	protein maturation
CYL17_17860	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CYL17_17905	COG0309	Hydrogenase expression formation protein (HypE)
CYL17_17910	COG0298	carbon dioxide binding
CYL17_17915	COG0409	Hydrogenase expression formation protein
CYL17_17930	COG1063	alcohol dehydrogenase
CYL17_17945	COG0247	lactate metabolic process
CYL17_17950	COG1139	Iron-sulfur cluster binding protein
CYL17_17955	COG1556	Lactate utilization protein
CYL17_17975	COG0395	ABC-type sugar transport system, permease component
CYL17_17980	COG1175	transmembrane transport
CYL17_18030	COG0477	Major facilitator Superfamily
CYL17_18035	COG0662	Cupin 2, conserved barrel domain protein
CYL17_18050	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CYL17_18060	COG0745	RESPONSE REGULATOR receiver
CYL17_18070	COG0577	efflux transmembrane transporter activity
CYL17_18070	COG1136	(ABC) transporter
CYL17_18075	COG1136	(ABC) transporter
CYL17_18090	COG2205	protein histidine kinase activity
CYL17_18095	COG0745	RESPONSE REGULATOR receiver
CYL17_18100	COG0579	oxidoreductase
CYL17_18120	COG1695	Transcriptional regulator
CYL17_18135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CYL17_18145	COG0667	Aldo Keto reductase
CYL17_18165	COG2252	PERMEase
CYL17_18185	COG1278	Cold shock
CYL17_18200	COG3973	AAA domain
CYL17_18205	COG0459	protein refolding
CYL17_18215	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CYL17_18230	COG4974	Belongs to the 'phage' integrase family
CYL17_18240	COG0717	Belongs to the dCTP deaminase family
CYL17_18380	COG2226	methyltransferase
CYL17_18425	COG1192	Involved in chromosome partitioning
CYL17_18570	COG0592	DNA-directed DNA polymerase activity
CYL17_18600	COG1609	Transcriptional regulator
CYL17_18765	COG3629	intracellular signal transduction
CYL17_18765	COG3903	Transcriptional regulator
CYL17_18810	COG0717	Belongs to the dCTP deaminase family