locus-tag	class	description
E6P07_00045	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E6P07_00050	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
E6P07_00055	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E6P07_00065	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E6P07_00070	ENOG4105DZP	Membrane-associated zinc metalloprotease
E6P07_00080	ENOG4105KNE	Phosphatidate cytidylyltransferase
E6P07_00085	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
E6P07_00090	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
E6P07_00095	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
E6P07_00100	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
E6P07_00105	ENOG4105CE9	30S ribosomal protein S2
E6P07_00110	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
E6P07_00115	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
E6P07_00130	ENOG4105E3S	small subunit
E6P07_00145	ENOG4105DPX	Hydrogenase, large subunit
E6P07_00155	ENOG4105CK7	Sodium proline symporter
E6P07_00175	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
E6P07_00180	ENOG4105W49	UPF0434 protein
E6P07_00195	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
E6P07_00200	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
E6P07_00210	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
E6P07_00215	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
E6P07_00220	ENOG4107S7U	Sulfide dehydrogenase
E6P07_00225	ENOG4105MW3	Cytochrome
E6P07_00230	ENOG4105JXB	ankyrin repeat-containing protein
E6P07_00235	ENOG4105CUW	cytochrome C-TYPE protein
E6P07_00240	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
E6P07_00290	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
E6P07_00295	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
E6P07_00300	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
E6P07_00310	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
E6P07_00330	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
E6P07_00345	ENOG4105CUW	cytochrome C-TYPE protein
E6P07_00355	ENOG4107TF3	peptidylprolyl cis-trans isomerase
E6P07_00360	ENOG4105K9H	YciI-like protein
E6P07_00365	ENOG4107835	probably involved in intracellular septation (By similarity)
E6P07_00370	ENOG4105BZG	amino acid carrier protein
E6P07_00380	ENOG4105BZU	Histidine kinase
E6P07_00385	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E6P07_00390	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
E6P07_00405	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
E6P07_00415	ENOG4108UHE	carbonic anhydrase
E6P07_00420	ENOG4105CQ7	ATP-dependent helicase
E6P07_00435	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
E6P07_00440	ENOG4108QV3	biosynthesis protein
E6P07_00460	ENOG4108YGX	
E6P07_00475	ENOG4105CFV	Tetratricopeptide repeat protein
E6P07_00480	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
E6P07_00485	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
E6P07_00490	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
E6P07_00495	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E6P07_00500	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
E6P07_00505	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
E6P07_00510	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
E6P07_00515	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
E6P07_00520	ENOG4105C3M	thioredoxin reductase
E6P07_00525	ENOG4105K4H	Nlp p60 protein
E6P07_00530	ENOG4106CXR	Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria (By similarity)
E6P07_00540	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
E6P07_00545	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E6P07_00550	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
E6P07_00555	ENOG4108Z1B	Cyclase dehydrase
E6P07_00560	ENOG4105VDB	UPF0125 protein
E6P07_00565	ENOG4105DSE	periplasmic solute binding protein
E6P07_00575	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E6P07_00580	ENOG41090R7	Ferric uptake
E6P07_00590	ENOG4108JA2	transcriptioN-repair coupling factor
E6P07_00625	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
E6P07_00630	ENOG4107YRI	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
E6P07_00635	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
E6P07_00650	ENOG4105ERG	peptidase m48, ste24p
E6P07_00670	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
E6P07_00675	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
E6P07_00680	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
E6P07_00685	ENOG4105CM2	brancheD-chain amino acid aminotransferase
E6P07_00700	ENOG4105VN1	Heat shock protein
E6P07_00705	ENOG41087EV	Hsp20/alpha crystallin family
E6P07_00750	ENOG4108IYU	L-aspartate oxidase
E6P07_00755	ENOG4105EMN	RNA polymerase sigma factor
E6P07_00765	ENOG4105VQK	sigma E regulatory protein, MucB RseB
E6P07_00775	ENOG4105C0H	protease
E6P07_00780	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
E6P07_00785	ENOG4105C3F	Signal peptidase i
E6P07_00795	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
E6P07_00805	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
E6P07_00810	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
E6P07_00815	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
E6P07_00830	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
E6P07_00835	ENOG4105UBK	short-chain dehydrogenase reductase
E6P07_00840	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E6P07_00845	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
E6P07_00855	ENOG4108UW8	fha domain-containing protein
E6P07_00860	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
E6P07_00870	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
E6P07_00885	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
E6P07_00890	ENOG4105NWN	ApaG protein
E6P07_00900	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
E6P07_00915	ENOG4105F8J	Adenylate Guanylate cyclase
E6P07_00920	ENOG4105DFG	type I secretion outer membrane protein
E6P07_00925	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
E6P07_00930	ENOG4105D8G	Major Facilitator superfamily
E6P07_00950	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
E6P07_00955	ENOG4105EEI	dihydropteroate synthase
E6P07_00960	ENOG4108JQC	penicillin-binding protein 1A
E6P07_00965	ENOG4105CHM	Aminotransferase
E6P07_00970	ENOG4105D6E	homoserine dehydrogenase
E6P07_00975	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
E6P07_00980	ENOG4105DIK	(ABC) transporter
E6P07_00990	ENOG4105MYN	Zinc uptake regulation protein
E6P07_01045	ENOG4108JQB	penicillin-binding protein 1C
E6P07_01050	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
E6P07_01060	ENOG4105C1J	atp-dependent rna helicase
E6P07_01065	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
E6P07_01075	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
E6P07_01120	ENOG4105C6K	Malic enzyme
E6P07_01125	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
E6P07_01130	ENOG4105CDV	Ompa motb domain protein
E6P07_01135	ENOG4105DJ9	glucan biosynthesis protein
E6P07_01175	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
E6P07_01185	ENOG4105FDK	ABC transporter
E6P07_01190	ENOG4105NXV	High-affinity zinc uptake system protein
E6P07_01205	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
E6P07_01210	ENOG4105DZB	Electron transport complex
E6P07_01220	ENOG4105D6A	Electron transport complex
E6P07_01230	ENOG4105C7S	Dehydrogenase
E6P07_01235	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
E6P07_01250	ENOG41076E6	Uroporphyrinogen-III Synthase
E6P07_01270	ENOG4105VFU	Rna-binding protein
E6P07_01275	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
E6P07_01280	ENOG4105DGW	oligopeptidase A
E6P07_01290	ENOG4105BZU	Histidine kinase
E6P07_01295	ENOG4105D2N	Aldolase
E6P07_01300	ENOG4105CA9	Pyruvate kinase
E6P07_01305	ENOG4105BZA	Phosphoglycerate kinase
E6P07_01315	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
E6P07_01320	ENOG4105CV1	Transketolase (EC 2.2.1.1)
E6P07_01330	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
E6P07_01335	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
E6P07_01340	ENOG4105SYT	Methylenetetrahydrofolate reductase
E6P07_01345	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
E6P07_01360	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
E6P07_01375	ENOG4105D5D	udp-galactopyranose mutase
E6P07_01380	ENOG4105ER6	polysaccharide biosynthesis protein
E6P07_01415	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E6P07_01425	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
E6P07_01435	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
E6P07_01445	ENOG4105D7V	transposase
E6P07_01460	ENOG4105CBS	Chea signal transduction histidine kinase
E6P07_01475	ENOG4106FIA	frizzy aggregation protein A
E6P07_01480	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E6P07_01485	ENOG4108KXV	response regulator
E6P07_01495	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E6P07_01500	ENOG4105BZU	Histidine kinase
E6P07_01505	ENOG4105CQ7	ATP-dependent helicase
E6P07_01510	ENOG4105C09	Bile acid
E6P07_01525	ENOG4105CKK	Glycosyl transferase, family 2
E6P07_01535	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E6P07_01545	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E6P07_01560	ENOG4107TDF	Formate hydrogenlyase subunit 4
E6P07_01565	ENOG4105D65	subunit l
E6P07_01585	ENOG4108R99	pseudouridine synthase
E6P07_01595	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
E6P07_01615	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
E6P07_01625	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
E6P07_01630	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
E6P07_01635	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
E6P07_01645	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E6P07_01650	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
E6P07_01655	ENOG4107YIM	Involved in the transcription termination process (By similarity)
E6P07_01660	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
E6P07_01665	ENOG4108ZAI	phosphatidylglycerophosphatase a
E6P07_01695	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E6P07_01705	ENOG4105EWK	phytoene
E6P07_01710	ENOG4105FE1	phytoene synthase
E6P07_01725	ENOG4105CTB	Polyprenyl synthetase
E6P07_01730	ENOG4107EPK	O-methyltransferase, family 2
E6P07_01735	ENOG4107XHQ	chlorophyll synthesis pathway, bchC
E6P07_01740	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
E6P07_01745	ENOG41060GA	Chlorophyllide reductase subunit Y
E6P07_01795	ENOG4105ZA6	Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers (By similarity)
E6P07_01800	ENOG41084RU	Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers
E6P07_01805	ENOG4105VGZ	photosynthetic reaction center L subunit
E6P07_01810	ENOG4107R94	photosynthetic reaction center, M subunit
E6P07_01825	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
E6P07_01830	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
E6P07_01835	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
E6P07_01840	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
E6P07_01850	ENOG4108S0S	Nucleotidyl transferase
E6P07_01860	ENOG4105C8V	SAICAR synthetase
E6P07_01870	ENOG4105KME	endoribonuclease L-psp
E6P07_01875	ENOG4105CVE	Lytic murein transglycosylase
E6P07_01885	ENOG4105CB5	ATP-dependent DNA helicase recG
E6P07_01890	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
E6P07_01895	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
E6P07_01900	ENOG4105CQB	FAD linked oxidase domain protein
E6P07_01905	ENOG4105W4M	Transport-associated protein
E6P07_01910	ENOG41082RQ	UPF0102 protein
E6P07_01915	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
E6P07_01920	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
E6P07_01930	ENOG4108V6E	Cell division protein mraZ
E6P07_01935	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
E6P07_01940	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
E6P07_01945	ENOG4105CJN	penicillin-binding protein
E6P07_01950	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
E6P07_01955	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
E6P07_01960	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
E6P07_01965	ENOG4105CNI	cell division protein FtsW
E6P07_01970	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
E6P07_01975	ENOG4105DFU	Cell wall formation (By similarity)
E6P07_01980	ENOG4105D4A	Cell wall formation (By similarity)
E6P07_01985	ENOG4105CPF	Cell wall formation (By similarity)
E6P07_01990	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
E6P07_01995	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
E6P07_02000	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
E6P07_02005	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E6P07_02015	ENOG4108K5P	(LipO)protein
E6P07_02020	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
E6P07_02025	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
E6P07_02030	ENOG4105M6F	mutator MutT protein
E6P07_02065	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
E6P07_02070	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
E6P07_02080	ENOG4105CDY	transcriptional regulatory protein
E6P07_02085	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
E6P07_02090	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
E6P07_02100	ENOG4105CHH	sulfate transporter
E6P07_02110	ENOG4108YZA	Nitrogen regulatory protein pii
E6P07_02115	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E6P07_02120	ENOG4105C34	Pseudouridine synthase
E6P07_02125	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
E6P07_02130	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
E6P07_02135	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E6P07_02140	ENOG4105CN1	protease
E6P07_02145	ENOG4105D9M	gamma-glutamylcysteine synthetase
E6P07_02150	ENOG4105C9X	ppx gppa phosphatase
E6P07_02155	ENOG4107QN2	dihydrolipoyl dehydrogenase
E6P07_02160	ENOG4107QSN	dihydrolipoamide acetyltransferase
E6P07_02165	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
E6P07_02170	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
E6P07_02175	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
E6P07_02185	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
E6P07_02190	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
E6P07_02195	ENOG4105EHM	Aminoglycoside phosphotransferase
E6P07_02215	ENOG4108VYJ	response regulator receiver protein
E6P07_02220	ENOG4105C12	Phosphoribosylglycinamide synthetase
E6P07_02225	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E6P07_02230	ENOG4105DC1	bifunctional purine biosynthesis protein purh
E6P07_02235	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
E6P07_02240	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E6P07_02250	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
E6P07_02255	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E6P07_02260	ENOG4105W8H	transhydrogenase (subunit alpha
E6P07_02265	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E6P07_02270	ENOG4105IPI	Membrane
E6P07_02295	ENOG4108B22	Protein CrcB homolog
E6P07_02305	ENOG4105C3K	feS assembly ATPase SufC
E6P07_02315	ENOG4105VG1	fes assembly suf system protein
E6P07_02325	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
E6P07_02340	ENOG4105DXN	mazG family
E6P07_02345	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
E6P07_02360	ENOG4107WDG	serine threonine protein kinase
E6P07_02365	ENOG4105DSJ	YicC domain protein
E6P07_02370	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
E6P07_02375	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
E6P07_02380	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E6P07_02385	ENOG4105ECY	inositol monophosphatase
E6P07_02400	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
E6P07_02420	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
E6P07_02440	ENOG4105CJ1	ABC, transporter
E6P07_02465	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
E6P07_02480	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
E6P07_02485	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
E6P07_02490	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
E6P07_02495	ENOG4105C72	UPF0176 protein
E6P07_02500	ENOG41080HT	Transcriptional regulator, arsr family
E6P07_02505	ENOG41063SB	peptidase
E6P07_02510	ENOG4105CN1	protease
E6P07_02515	ENOG4107S0N	DJ-1 family
E6P07_02520	ENOG4105ESV	Glycosyl transferase, family 4
E6P07_02530	ENOG4107QHF	type ii secretion system protein e
E6P07_02535	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
E6P07_02540	ENOG4108UJD	30S ribosomal protein S9
E6P07_02550	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
E6P07_02560	ENOG4105CGH	5'-nucleotidase
E6P07_02565	ENOG4105W0E	50S ribosomal protein L33
E6P07_02570	ENOG4105KDC	50s ribosomal protein l28
E6P07_02580	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
E6P07_02585	ENOG4105CBS	Chea signal transduction histidine kinase
E6P07_02590	ENOG4105C8Q	Methyl-accepting chemotaxis
E6P07_02600	ENOG4105M3Z	response regulator
E6P07_02605	ENOG4108UNF	response regulator
E6P07_02610	ENOG4105D7Z	glutathione synthase
E6P07_02625	ENOG4108UJU	UPF0301 protein
E6P07_02630	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
E6P07_02640	ENOG4105CXT	aspartate transcarbamylase
E6P07_02645	ENOG4105CD3	dihydroorotase
E6P07_02650	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
E6P07_02655	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
E6P07_02665	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
E6P07_02670	ENOG4107RH8	nuclease SbcCD subunit D
E6P07_02680	ENOG4105DJ0	Poly(A) Polymerase
E6P07_02685	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
E6P07_02695	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
E6P07_02700	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
E6P07_02705	ENOG4105BZU	Histidine kinase
E6P07_02715	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
E6P07_02720	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
E6P07_02730	ENOG4107QHF	type ii secretion system protein e
E6P07_02740	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E6P07_02750	ENOG41080XQ	Signal transduction protein with cbs domains
E6P07_02755	ENOG4105DDQ	anthranilate synthase
E6P07_02760	ENOG4108I0Q	anthranilate phosphoribosyltransferase
E6P07_02765	ENOG4105DK0	Indole-3-glycerol phosphate synthase
E6P07_02770	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
E6P07_02775	ENOG4108UKZ	OsmC family
E6P07_02780	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
E6P07_02795	ENOG4105D7Q	type ii secretion system
E6P07_02800	ENOG4108VAU	general secretion pathway protein G
E6P07_02805	ENOG4105WMT	general secretion pathway protein h
E6P07_02820	ENOG4105UV2	general secretion pathway protein K
E6P07_02870	ENOG4105GVR	general secretion pathway protein D
E6P07_02905	ENOG4105CK2	sodium dicarboxylate symporter
E6P07_02910	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
E6P07_02925	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
E6P07_02950	ENOG4105D0M	Protease HtpX homolog
E6P07_02955	ENOG41080IJ	Diacylglycerol kinase
E6P07_02960	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E6P07_02965	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E6P07_02970	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
E6P07_02975	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
E6P07_02990	ENOG4108ZJ4	polysaccharide deacetylase
E6P07_03000	ENOG4105C8T	Leucyl-tRNA synthetase
E6P07_03005	ENOG4108U2H	Rare lipoprotein B
E6P07_03010	ENOG4105ECY	inositol monophosphatase
E6P07_03020	ENOG4105C3G	gtp-binding protein
E6P07_03025	ENOG4105C7K	acetolactate synthase
E6P07_03030	ENOG4108ZP8	Acetolactate synthase small subunit
E6P07_03035	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
E6P07_03040	ENOG4107YD3	Thioesterase
E6P07_03045	ENOG4105E02	MotA TolQ exbB proton channel
E6P07_03050	ENOG4105M8F	Biopolymer transport protein exbD tolR
E6P07_03060	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
E6P07_03065	ENOG4105KCK	Peptidoglycan-associated lipoprotein
E6P07_03070	ENOG4105UFD	tol-pal system protein YbgF
E6P07_03075	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E6P07_03080	ENOG4105BZU	Histidine kinase
E6P07_03085	ENOG4105M85	Bola protein
E6P07_03100	ENOG4105CJ1	ABC, transporter
E6P07_03110	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
E6P07_03115	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
E6P07_03125	ENOG4105BZU	Histidine kinase
E6P07_03130	ENOG4105C8Q	Methyl-accepting chemotaxis
E6P07_03135	ENOG4105BZU	Histidine kinase
E6P07_03155	ENOG4108IUW	ABC transporter
E6P07_03160	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
E6P07_03180	ENOG4105BZU	Histidine kinase
E6P07_03185	ENOG4105ENE	Histidine kinase
E6P07_03190	ENOG4105WH1	Two component transcriptional regulator luxr family
E6P07_03195	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
E6P07_03200	ENOG4105N5T	Radical SAM Protein
E6P07_03205	ENOG4105CFP	Peptidase U32
E6P07_03210	ENOG4106RZ4	Peptidase U32
E6P07_03230	ENOG4105BZU	Histidine kinase
E6P07_03240	ENOG4105C5Q	Transcriptional regulator
E6P07_03245	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E6P07_03260	ENOG4105CJW	magnesium transporter
E6P07_03270	ENOG4105DUM	transcriptional regulator, lysR family
E6P07_03275	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
E6P07_03280	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
E6P07_03310	ENOG4105CKW	Inner membrane protein yedI
E6P07_03315	ENOG4105XPQ	lipid carrier protein
E6P07_03330	ENOG4108TEB	UPF0114 protein
E6P07_03335	ENOG4105BZU	Histidine kinase
E6P07_03340	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
E6P07_03360	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
E6P07_03365	ENOG4105WBS	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
E6P07_03385	ENOG4105DB1	molybdopterin oxidoreductase
E6P07_03390	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
E6P07_03395	ENOG4108KDI	dmso reductase anchor subunit
E6P07_03405	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
E6P07_03425	ENOG4105C5H	ABC transporter
E6P07_03430	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E6P07_03450	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E6P07_03455	ENOG4108Z6B	deaminase
E6P07_03460	ENOG4105W3S	hemerythrin-like, metal-binding protein
E6P07_03495	ENOG4105DB7	PHP domain protein
E6P07_03500	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
E6P07_03505	ENOG4108Z4T	Peptidase M50
E6P07_03510	ENOG4105C31	Tryptophanyl-tRNA synthetase
E6P07_03520	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
E6P07_03525	ENOG4105FE9	pseudouridine synthase
E6P07_03530	ENOG41061WM	D-Alanyl-D-Alanine
E6P07_03535	ENOG4105C8J	)-transporter
E6P07_03540	ENOG4107T5V	SNARE associated Golgi
E6P07_03560	ENOG4108V1U	phospholipid-binding protein
E6P07_03565	ENOG4108M1T	Cytochrome c-type biogenesis protein
E6P07_03570	ENOG4105KWW	Biogenesis protein
E6P07_03575	ENOG4107QX9	Thiol disulfide interChange protein
E6P07_03580	ENOG4105DA4	cytochrome c-type biogenesis protein
E6P07_03585	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
E6P07_03595	ENOG41060IM	Heme exporter protein
E6P07_03600	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
E6P07_03605	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
E6P07_03610	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
E6P07_03615	ENOG4105N1F	Hnh endonuclease
E6P07_03625	ENOG4107QN1	sodium solute
E6P07_03630	ENOG41062QD	Membrane
E6P07_03670	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
E6P07_03680	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
E6P07_03690	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
E6P07_03695	ENOG41067HS	methyltransferase
E6P07_03705	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E6P07_03725	ENOG4105E6M	Sulphatase-modifying factor protein
E6P07_03735	ENOG4106DSS	Tartrate dehydratase subunit alpha
E6P07_03780	ENOG4105C22	threonyL-tRNA synthetase
E6P07_03790	ENOG41082NX	50s ribosomal protein l35
E6P07_03795	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
E6P07_03800	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
E6P07_03805	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
E6P07_03810	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
E6P07_03815	ENOG4105WJX	transcriptional regulator MERR family
E6P07_03860	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E6P07_03915	ENOG4105C8Q	Methyl-accepting chemotaxis
E6P07_03920	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
E6P07_03930	ENOG4107QY8	reductase
E6P07_03945	ENOG4108Z5K	methylglyoxal synthase
E6P07_03965	ENOG4105D1F	ATP-binding protein
E6P07_03990	ENOG4105BZU	Histidine kinase
E6P07_04020	ENOG4105KZX	Pterin carbinolamine dehydratase
E6P07_04030	ENOG4108UQS	dipeptidase
E6P07_04040	ENOG4105E0A	ABC, transporter
E6P07_04045	ENOG4105EHG	Permease protein
E6P07_04065	ENOG4109015	Biopolymer transport protein exbD tolR
E6P07_04070	ENOG4108ZZF	transport protein (ExbD)
E6P07_04080	ENOG4105D6J	arsenicaL-resistance protein
E6P07_04110	ENOG4108JPZ	Monovalent cation H antiporter subunit D
E6P07_04120	ENOG4107TDF	Formate hydrogenlyase subunit 4
E6P07_04125	ENOG4108JPZ	Monovalent cation H antiporter subunit D
E6P07_04135	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
E6P07_04145	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
E6P07_04150	ENOG4105E0C	molybdate abc transporter
E6P07_04160	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
E6P07_04165	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
E6P07_04170	ENOG4107XWS	modD protein
E6P07_04175	ENOG4105F4R	Transcriptional regulator mode
E6P07_04185	ENOG4105EMN	RNA polymerase sigma factor
E6P07_04190	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E6P07_04205	ENOG4105PGM	cation diffusion facilitator family transporter
E6P07_04210	ENOG4105CP7	Triose-phosphate isomerase
E6P07_04215	ENOG4107EJC	Preprotein translocase subunit SecG
E6P07_04225	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E6P07_04230	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E6P07_04235	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E6P07_04240	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E6P07_04250	ENOG4107QIZ	NADH dehydrogenase
E6P07_04255	ENOG4108IEH	NADH dehydrogenase subunit g
E6P07_04260	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
E6P07_04265	ENOG41081XG	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E6P07_04270	ENOG4105DF2	NADH dehydrogenase subunit j
E6P07_04275	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E6P07_04285	ENOG4105C8S	subunit m
E6P07_04290	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E6P07_04295	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E6P07_04300	ENOG4105GJM	(LipO)protein
E6P07_04310	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
E6P07_04315	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
E6P07_04320	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
E6P07_04325	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E6P07_04330	ENOG4105VFK	BolA family
E6P07_04335	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
E6P07_04340	ENOG4105CH7	arginosuccinase
E6P07_04345	ENOG4105D06	uba thif-type nad fad binding protein
E6P07_04355	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
E6P07_04365	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
E6P07_04370	ENOG4105CHV	Transcription elongation factor NusA
E6P07_04375	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
E6P07_04380	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
E6P07_04385	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
E6P07_04390	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
E6P07_04395	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
E6P07_04400	ENOG4105MRR	Transcriptional regulator (By similarity)
E6P07_04470	ENOG4108A51	
E6P07_04475	ENOG4107XQ1	cobalamin (vitamin B12) biosynthesis CbiM protein
E6P07_04495	ENOG4105C0H	protease
E6P07_04500	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
E6P07_04515	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
E6P07_04520	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E6P07_04525	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
E6P07_04530	ENOG4105MJ2	Competence protein
E6P07_04535	ENOG4108303	d-xylulose 5-phosphate d-fructose 6-phosphate phosphoketolase
E6P07_04550	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
E6P07_04565	ENOG4105D58	Diguanylate phosphodiesterase
E6P07_04575	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E6P07_04580	ENOG4105BZU	Histidine kinase
E6P07_04610	ENOG4105C1A	potassium transporter peripheral membrane
E6P07_04615	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E6P07_04620	ENOG4105ES5	Histidine kinase
E6P07_04630	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
E6P07_04635	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
E6P07_04640	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E6P07_04650	ENOG4105C79	DNA protecting protein DprA
E6P07_04655	ENOG4108RPN	Protein smg homolog
E6P07_04670	ENOG4105DR4	Methyltransferase
E6P07_04675	ENOG4105CSR	polyphosphate kinase 2
E6P07_04695	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
E6P07_04700	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E6P07_04705	ENOG4105CRE	cytochrome C
E6P07_04715	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E6P07_04725	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
E6P07_04795	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
E6P07_04800	ENOG4108UNF	response regulator
E6P07_04805	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
E6P07_04815	ENOG4105C0B	DNA polymerase III (alpha subunit)
E6P07_04825	ENOG4105C2M	dna polymerase I
E6P07_04835	ENOG4105CHC	glucokinase (EC 2.7.1.2)
E6P07_04840	ENOG4105CFU	surface antigen
E6P07_04845	ENOG4105MA0	exported protein
E6P07_04850	ENOG4105D1S	lipid A biosynthesis
E6P07_04870	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
E6P07_04875	ENOG4107QR8	Thioredoxin
E6P07_04880	ENOG4105K63	Thioredoxin
E6P07_04885	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
E6P07_04890	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
E6P07_04895	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
E6P07_04900	ENOG4105E1F	short-chain dehydrogenase reductase
E6P07_04920	ENOG4105C9M	aspartyl-trna synthetase
E6P07_04925	ENOG4108Z4K	mutator MutT protein
E6P07_04930	ENOG4105BZ1	(ABC) transporter
E6P07_04960	ENOG4105EI2	Pseudouridine synthase
E6P07_04965	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E6P07_04980	ENOG4105BZS	acriflavin resistance protein
E6P07_04985	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
E6P07_05000	ENOG4105CSM	endonuclease III
E6P07_05005	ENOG4105E4C	Lytic transglycosylase catalytic
E6P07_05025	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E6P07_05030	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E6P07_05050	ENOG4105C5H	ABC transporter
E6P07_05060	ENOG4105CVG	Homoserine O-transsuccinylase
E6P07_05085	ENOG4105G15	CRISPR-associated RAMP protein, Csm5 family
E6P07_05095	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
E6P07_05170	ENOG4105M00	molybdopterin converting factor, subunit 1
E6P07_05185	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E6P07_05190	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
E6P07_05195	ENOG4105C01	Dihydroxy-acid dehydratase
E6P07_05230	ENOG4105DFP	Integrase
E6P07_05275	ENOG4105DZR	Type I site-specific deoxyribonuclease
E6P07_05295	ENOG4105DBV	ornithine carbamoyltransferase
E6P07_05300	ENOG4105C8Y	Acetylornithine aminotransferase
E6P07_05305	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E6P07_05315	ENOG4105M2J	Glutaredoxin
E6P07_05320	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
E6P07_05325	ENOG410903C	(LipO)protein
E6P07_05330	ENOG4105EKE	dihydroorotase
E6P07_05360	ENOG4105BZU	Histidine kinase
E6P07_05365	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E6P07_05390	ENOG4105DN3	alpha-2-macroglobulin domain protein
E6P07_05400	ENOG4107QQG	Dehydrogenase
E6P07_05405	ENOG4105C7B	Threonine dehydratase
E6P07_05410	ENOG4105CYN	Serine protein kinase
E6P07_05415	ENOG4106AKX	UPF0229 protein
E6P07_05420	ENOG4105ED1	spovr family
E6P07_05425	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
E6P07_05430	ENOG4105K6T	rare lipoprotein A
E6P07_05435	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
E6P07_05440	ENOG4105DJ4	phosphatidylserine decarboxylase
E6P07_05460	ENOG4108RH0	Crea protein
E6P07_05465	ENOG4105BZU	Histidine kinase
E6P07_05485	ENOG4105BZU	Histidine kinase
E6P07_05490	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
E6P07_05500	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
E6P07_05520	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
E6P07_05525	ENOG4105K4G	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
E6P07_05540	ENOG4107WUB	V-type ATPase 116 kDa subunit
E6P07_05570	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E6P07_05585	ENOG4105EHG	Permease protein
E6P07_05590	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
E6P07_05610	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
E6P07_05620	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
E6P07_05625	ENOG41081F0	Precorrin-8x methylmutase
E6P07_05635	ENOG4105C8Q	Methyl-accepting chemotaxis
E6P07_05650	ENOG41079YP	Citrate utilization protein b
E6P07_05655	ENOG4107EFR	Flavocytochrome c
E6P07_05660	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
E6P07_05670	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
E6P07_05685	ENOG4105DFU	Cell wall formation (By similarity)
E6P07_05690	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
E6P07_05695	ENOG4108VYJ	response regulator receiver protein
E6P07_05700	ENOG4105CBS	Chea signal transduction histidine kinase
E6P07_05705	ENOG4108V3W	Chemotaxis protein, CheW
E6P07_05710	ENOG4105BZU	Histidine kinase
E6P07_05715	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
E6P07_05720	ENOG4105C8Q	Methyl-accepting chemotaxis
E6P07_05725	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E6P07_05740	ENOG4105C8Q	Methyl-accepting chemotaxis
E6P07_05750	ENOG4105C6T	cysteine synthase
E6P07_05760	ENOG4105K64	Glycosyl transferase, family 2
E6P07_05765	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
E6P07_05770	ENOG4105CMR	udp-glucose 4-epimerase
E6P07_05780	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
E6P07_05785	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
E6P07_05805	ENOG4105C8H	hydrogenase maturation protein Hypf
E6P07_05810	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E6P07_05815	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
E6P07_05825	ENOG4105MQ3	flagellar protein FliS
E6P07_05860	ENOG4105FAW	cDP-glucose 4,6-dehydratase
E6P07_05865	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
E6P07_05880	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
E6P07_05885	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E6P07_05890	ENOG4105N21	Membrane
E6P07_05895	ENOG4105CUT	histidyl-tRNA synthetase
E6P07_05905	ENOG41090FY	type IV pilus biogenesis stability protein PilW
E6P07_05910	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
E6P07_05915	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
E6P07_05930	ENOG4105CRK	lysyL-tRNA synthetase
E6P07_05935	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
E6P07_05945	ENOG4105EAQ	(twin-arginine translocation) pathway signal
E6P07_05950	ENOG4105E4C	Lytic transglycosylase catalytic
E6P07_05965	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
E6P07_05970	ENOG4105CEN	a g-specific adenine glycosylase
E6P07_05985	ENOG4108IQE	Amp-dependent synthetase and ligase
E6P07_06000	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
E6P07_06015	ENOG4105CD5	CoA-binding domain protein
E6P07_06050	ENOG41085EG	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
E6P07_06055	ENOG41085GJ	domain protein
E6P07_06065	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
E6P07_06080	ENOG4108VYJ	response regulator receiver protein
E6P07_06095	ENOG4108V3W	Chemotaxis protein, CheW
E6P07_06100	ENOG4105BZU	Histidine kinase
E6P07_06105	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
E6P07_06110	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E6P07_06185	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
E6P07_06190	ENOG4108JU5	Magnesium and cobalt efflux protein
E6P07_06195	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
E6P07_06200	ENOG4105C9A	Phoh family
E6P07_06205	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
E6P07_06230	ENOG4105D65	subunit l
E6P07_06240	ENOG4108JPZ	Monovalent cation H antiporter subunit D
E6P07_06245	ENOG4108JPZ	Monovalent cation H antiporter subunit D
E6P07_06250	ENOG4108JPZ	Monovalent cation H antiporter subunit D
E6P07_06260	ENOG4105DGN	Electron transport complex
E6P07_06265	ENOG4108R3D	Electron transport complex
E6P07_06275	ENOG4105DH7	May be involved in recombination (By similarity)
E6P07_06280	ENOG4108JU6	CBS domain protein
E6P07_06290	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
E6P07_06295	ENOG4105CFH	Aspartokinase
E6P07_06300	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
E6P07_06305	ENOG4105Y3E	Modulates RecA activity (By similarity)
E6P07_06310	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
E6P07_06315	ENOG4107TH8	cina domain protein
E6P07_06335	ENOG4107QSA	Oxaloacetate decarboxylase
E6P07_06340	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E6P07_06355	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
E6P07_06370	ENOG4105EYM	Major Facilitator superfamily
E6P07_06380	ENOG4105VEQ	Cold shock protein
E6P07_06385	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
E6P07_06390	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E6P07_06420	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E6P07_06425	ENOG4105K46	50S ribosomal protein l27
E6P07_06435	ENOG4105EAH	synthase
E6P07_06445	ENOG4105CJ2	(LipO)protein
E6P07_06450	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
E6P07_06460	ENOG4105CHM	Aminotransferase
E6P07_06465	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
E6P07_06480	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
E6P07_06485	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E6P07_06495	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
E6P07_06500	ENOG4105BZ1	(ABC) transporter
E6P07_06505	ENOG4105M8F	Biopolymer transport protein exbD tolR
E6P07_06530	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
E6P07_06535	ENOG4105BZU	Histidine kinase
E6P07_06540	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E6P07_06545	ENOG4105VCC	30S ribosomal protein S21
E6P07_06555	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
E6P07_06560	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E6P07_06575	ENOG4108ETH	Formylglycinamide ribotide synthetase
E6P07_06580	ENOG4105C2N	RNA methyltransferase TrmH family group 3
E6P07_06585	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
E6P07_06595	ENOG4107QTF	adenylosuccinate lyase
E6P07_06605	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
E6P07_06610	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
E6P07_06615	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
E6P07_06620	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
E6P07_06625	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
E6P07_06630	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
E6P07_06635	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
E6P07_06645	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
E6P07_06650	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
E6P07_06660	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E6P07_06665	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E6P07_06680	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
E6P07_06695	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
E6P07_06700	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
E6P07_06705	ENOG4107BJW	polysaccharide deacetylase
E6P07_06710	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
E6P07_06715	ENOG41075W9	High frequency lysogenization protein HflD homolog
E6P07_06720	ENOG4107QM5	aconitate hydratase
E6P07_06730	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
E6P07_06735	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
E6P07_06740	ENOG4105D9N	nucleoside
E6P07_06745	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
E6P07_06750	ENOG4105C9B	Cysteine desulfurase
E6P07_06760	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E6P07_06765	ENOG4105F38	ABC transporter, permease
E6P07_06770	ENOG4105D38	putrescine abc transporter
E6P07_06775	ENOG4105C28	cystathionine
E6P07_06780	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
E6P07_06805	ENOG4105E4F	Isochorismate synthase
E6P07_06810	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
E6P07_06815	ENOG4108IPT	Naphthoate synthase
E6P07_06820	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
E6P07_06825	ENOG4107S8C	mandelate racemase muconate lactonizing
E6P07_06830	ENOG4105BZU	Histidine kinase
E6P07_06840	ENOG4105E2V	Glycosyltransferase 36
E6P07_06855	ENOG4105DVT	helicase
E6P07_06860	ENOG4107XCC	Catalyzes the synthesis of activated sulfate (By similarity)
E6P07_06875	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E6P07_06880	ENOG4108YZY	peptidylprolyl cis-trans isomerase
E6P07_06905	ENOG4107RIQ	Sulfate adenylate transferase
E6P07_06915	ENOG4105BZ4	penicillin-binding protein
E6P07_06920	ENOG4105E3A	(ABC) transporter
E6P07_06925	ENOG4105DA5	(ABC) transporter
E6P07_06940	ENOG4105CDV	Ompa motb domain protein
E6P07_06945	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
E6P07_06950	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
E6P07_06975	ENOG4105DPX	Hydrogenase, large subunit
E6P07_07000	ENOG4105CH5	extracellular solute-binding protein, family 7
E6P07_07005	ENOG4105BZU	Histidine kinase
E6P07_07010	ENOG4105BZU	Histidine kinase
E6P07_07015	ENOG4105BZU	Histidine kinase
E6P07_07020	ENOG4105BZU	Histidine kinase
E6P07_07065	ENOG4105C0D	helicase
E6P07_07080	ENOG4105CZX	twitching motility protein
E6P07_07085	ENOG4105CZX	twitching motility protein
E6P07_07090	ENOG4105C0P	Mg chelatase subunit ChlI
E6P07_07095	ENOG4105W0Z	cytoplasmic protein
E6P07_07105	ENOG4108YZA	Nitrogen regulatory protein pii
E6P07_07110	ENOG4105BZU	Histidine kinase
E6P07_07125	ENOG4105CDH	Citrulline--aspartate ligase
E6P07_07140	ENOG4105C1J	atp-dependent rna helicase
E6P07_07150	ENOG4108ZT0	50S ribosomal protein l17
E6P07_07155	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E6P07_07160	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
E6P07_07165	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
E6P07_07170	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
E6P07_07175	ENOG41067V7	50S ribosomal protein L36
E6P07_07180	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
E6P07_07185	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
E6P07_07190	ENOG4105VPB	50S ribosomal protein L30
E6P07_07195	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
E6P07_07200	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
E6P07_07205	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
E6P07_07210	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
E6P07_07215	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
E6P07_07220	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
E6P07_07225	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
E6P07_07230	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
E6P07_07235	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
E6P07_07245	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
E6P07_07250	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
E6P07_07255	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
E6P07_07260	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
E6P07_07265	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
E6P07_07270	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
E6P07_07275	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
E6P07_07280	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
E6P07_07285	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
E6P07_07290	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
E6P07_07295	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
E6P07_07300	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
E6P07_07305	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
E6P07_07310	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E6P07_07315	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E6P07_07320	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
E6P07_07325	ENOG4108VZM	50s ribosomal protein L10
E6P07_07330	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
E6P07_07335	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
E6P07_07340	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
E6P07_07345	ENOG4105PM1	preprotein translocase subunit SecE
E6P07_07355	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
E6P07_07375	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E6P07_07390	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
E6P07_07395	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E6P07_07400	ENOG41082J7	Rhodanese domain protein
E6P07_07405	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
E6P07_07410	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
E6P07_07415	ENOG4105C7K	acetolactate synthase
E6P07_07420	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
E6P07_07435	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
E6P07_07440	ENOG4107TYR	Glycosyl Transferase
E6P07_07445	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
E6P07_07450	ENOG4105CUJ	penicillin amidase
E6P07_07470	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E6P07_07480	ENOG4107SV1	subunit D
E6P07_07490	ENOG4106I2R	Coenzyme F420 hydrogenase dehydrogenase, beta
E6P07_07495	ENOG4105DTN	riboflavin biosynthesis protein ribF
E6P07_07545	ENOG4105DGN	Electron transport complex
E6P07_07550	ENOG4105DZB	Electron transport complex
E6P07_07555	ENOG41080WF	Electron transport complex, RnfABCDGE type, G subunit
E6P07_07560	ENOG4105D6A	Electron transport complex
E6P07_07565	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
E6P07_07570	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
E6P07_07575	ENOG4107SVV	electron transport complex, RnfABCDGE type, B subunit
E6P07_07600	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
E6P07_07605	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
E6P07_07610	ENOG4107TUY	Histidine kinase
E6P07_07620	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
E6P07_07625	ENOG4105CFG	Acts as a chaperone (By similarity)
E6P07_07630	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
E6P07_07635	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
E6P07_07640	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
E6P07_07645	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
E6P07_07655	ENOG4105CPI	Metal Dependent Phosphohydrolase
E6P07_07665	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
E6P07_07675	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E6P07_07685	ENOG4108JQ1	Dehydrogenase
E6P07_07690	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
E6P07_07700	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E6P07_07710	ENOG4105F8V	Hydrolase, tatD family
E6P07_07725	ENOG4105CSA	Coproporphyrinogen iii oxidase
E6P07_07730	ENOG4107QW8	radical SAM domain protein
E6P07_07745	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E6P07_07750	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E6P07_07755	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
E6P07_07775	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
E6P07_07780	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
E6P07_07795	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
E6P07_07800	ENOG4105CDU	Replicative dna helicase
E6P07_07805	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
E6P07_07820	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
E6P07_07840	ENOG4105RH4	Glycine cleavage system transcriptional repressor
E6P07_07845	ENOG4108IAB	Phoh family
E6P07_07875	ENOG4105C0D	helicase
E6P07_07910	ENOG4105CG3	alpha amylase, catalytic region
E6P07_07915	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
E6P07_07920	ENOG4105CFG	Acts as a chaperone (By similarity)
E6P07_07930	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
E6P07_07950	ENOG4107Y2X	deaminase
E6P07_07960	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
E6P07_07970	ENOG4108NWD	Cytochrome
E6P07_07980	ENOG4105E3S	small subunit
E6P07_07985	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
E6P07_07990	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
E6P07_07995	ENOG4105DPX	Hydrogenase, large subunit
E6P07_08000	ENOG4108USZ	hydrogenase
E6P07_08005	ENOG4105C8Q	Methyl-accepting chemotaxis
E6P07_08015	ENOG4105MUA	Resistance protein
E6P07_08025	ENOG4105EFT	decarboxylase
E6P07_08030	ENOG41076QQ	Glycosyl transferase, family 2
E6P07_08035	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
E6P07_08040	ENOG4105CNU	cell division protein FtsK
E6P07_08065	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E6P07_08070	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E6P07_08080	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
E6P07_08085	ENOG4105EIN	peptidylprolyl cis-trans isomerase
E6P07_08100	ENOG4105K70	DNA-binding protein
E6P07_08105	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
E6P07_08110	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
E6P07_08115	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
E6P07_08120	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
E6P07_08125	ENOG4105D4P	Coproporphyrinogen iii oxidase
E6P07_08130	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
E6P07_08135	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
E6P07_08145	ENOG41080RH	Thioredoxin
E6P07_08150	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
E6P07_08155	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
E6P07_08160	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
E6P07_08175	ENOG4108ZNX	Heat shock protein
E6P07_08185	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
E6P07_08195	ENOG4105E3S	small subunit
E6P07_08215	ENOG4105CXN	decarboxylase
E6P07_08220	ENOG4105CGK	Exodeoxyribonuclease III
E6P07_08230	ENOG4105C7Z	Conserved Protein
E6P07_08235	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
E6P07_08240	ENOG4105C0H	protease
E6P07_08300	ENOG4105VXP	Protein of unknown function DUF86
E6P07_08330	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
E6P07_08335	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
E6P07_08340	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
E6P07_08350	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
E6P07_08355	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
E6P07_08360	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
E6P07_08365	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
E6P07_08380	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
E6P07_08390	ENOG4105DTJ	flagellar hook-associated protein
E6P07_08395	ENOG4105E1Q	flagellar hook-associated protein
E6P07_08400	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
E6P07_08405	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
E6P07_08410	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
E6P07_08415	ENOG4105CGA	flagellar basal-body rod protein FlgG
E6P07_08420	ENOG4108KPB	Flagellar basal-body rod protein FlgF
E6P07_08425	ENOG4105BZE	flagellar hook protein, FlgE
E6P07_08430	ENOG4105W00	Flagellar hook capping protein
E6P07_08435	ENOG4108ZC9	flagellar basal-body rod protein flgc
E6P07_08440	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
E6P07_08445	ENOG4105BZU	Histidine kinase
E6P07_08450	ENOG4107R88	Chemotaxis protein (CheV)
E6P07_08485	ENOG4108ZXC	Two component transcriptional regulator, luxr family
E6P07_08490	ENOG4105BZU	Histidine kinase
E6P07_08500	ENOG4108K5H	permease YjgP YjgQ family protein
E6P07_08505	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
E6P07_08510	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
E6P07_08520	ENOG4105C5H	ABC transporter
E6P07_08525	ENOG4105CD8	aminopeptidase N
E6P07_08530	ENOG4105VW4	glutaredoxin 3
E6P07_08535	ENOG4105VEJ	Heat shock protein
E6P07_08545	ENOG4108R85	Short chain dehydrogenase
E6P07_08555	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
E6P07_08560	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
E6P07_08565	ENOG4105CS1	NAD(P)H quinone oxidoreductase
E6P07_08575	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
E6P07_08580	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
E6P07_08585	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
E6P07_08605	ENOG4108YZ4	nudix hydrolase
E6P07_08610	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E6P07_08615	ENOG4105BZU	Histidine kinase
E6P07_08620	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
E6P07_08625	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
E6P07_08630	ENOG4105CAT	Cytidine monophosphate kinase
E6P07_08635	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
E6P07_08640	ENOG4105HBR	Rna-binding protein
E6P07_08645	ENOG4105DHP	deoxycytidine triphosphate deaminase
E6P07_08650	ENOG4105CMR	udp-glucose 4-epimerase
E6P07_08665	ENOG4105E33	succinate dehydrogenase
E6P07_08670	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E6P07_08685	ENOG4105E96	Colicin v production protein
E6P07_08700	ENOG4105MEP	Peptidase S24-like
E6P07_08705	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E6P07_08710	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
E6P07_08745	ENOG4105BZU	Histidine kinase
E6P07_08750	ENOG4105CUZ	uba thif-type nad fad binding protein
E6P07_08755	ENOG4108R96	Methyltransferase, YaeB family
E6P07_08760	ENOG4107YTP	response regulator receiver protein
E6P07_08775	ENOG4105CJB	Exodeoxyribonuclease I
E6P07_08780	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
E6P07_08785	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
E6P07_08790	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
E6P07_08795	ENOG4105K5M	30s ribosomal protein S16
E6P07_08800	ENOG4108JJ9	ABC, transporter
E6P07_08805	ENOG4108JJ8	(ABC) transporter
E6P07_08825	ENOG41072GX	Peptidase M22 Glycoprotease
E6P07_08835	ENOG4105D1Z	hydroxypyruvate reductase
E6P07_08865	ENOG4105C4R	Atp-dependent dna helicase
E6P07_08875	ENOG4105EYA	deoxyribonuclease
E6P07_08880	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
E6P07_08895	ENOG4105C5X	domain protein
E6P07_08930	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
E6P07_08945	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
E6P07_08970	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
E6P07_08975	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
E6P07_08980	ENOG4107QIZ	NADH dehydrogenase
E6P07_08985	ENOG4108IEH	NADH dehydrogenase subunit g
E6P07_09010	ENOG4107QRG	dna polymerase iii
E6P07_09015	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
E6P07_09020	ENOG4105HHA	aminodeoxychorismate lyase
E6P07_09025	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
E6P07_09030	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E6P07_09035	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
E6P07_09040	ENOG4105CHR	reductase
E6P07_09045	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
E6P07_09050	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
E6P07_09055	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
E6P07_09060	ENOG4105VGS	50s ribosomal protein l32
E6P07_09065	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
E6P07_09070	ENOG4108ZXC	Two component transcriptional regulator, luxr family
E6P07_09075	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E6P07_09085	ENOG4107QVM	von Willebrand factor, type A
E6P07_09105	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
E6P07_09115	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E6P07_09120	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
E6P07_09125	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
E6P07_09130	ENOG4107QX9	Thiol disulfide interChange protein
E6P07_09135	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
E6P07_09140	ENOG4105VF7	tolerance protein
E6P07_09145	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
E6P07_09160	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
E6P07_09165	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
E6P07_09170	ENOG4108DQ3	n-acetylglutamate synthase
E6P07_09175	ENOG4105EGS	Mechanosensitive ion channel
E6P07_09190	ENOG4105CHR	reductase
E6P07_09205	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
E6P07_09220	ENOG4105DP0	ferredoxin-NADP reductase
E6P07_09225	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
E6P07_09235	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
E6P07_09275	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
E6P07_09280	ENOG4108J2R	molybdopterin oxidoreductase
E6P07_09285	ENOG4105C3R	Methionine synthase
E6P07_09295	ENOG4105C9B	Cysteine desulfurase
E6P07_09305	ENOG4108J5G	6-phosphogluconate dehydrogenase
E6P07_09310	ENOG4108UHJ	MAF-like protein
E6P07_09315	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
E6P07_09330	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
E6P07_09340	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
E6P07_09365	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
E6P07_09375	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
E6P07_09380	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
E6P07_09385	ENOG4105PJW	Sulfite reductase dissimilatory-type beta subunit
E6P07_09390	ENOG4105CY1	sulfite reductase, dissimilatory-type alpha subunit
E6P07_09405	ENOG4108XKQ	CRISPR-associated protein, Cas6-related
E6P07_09410	ENOG41080ZE	Adenylate cyclase
E6P07_09415	ENOG4108MN8	Membrane
E6P07_09425	ENOG4105KPY	Small multidrug resistance protein
E6P07_09430	ENOG4107QX8	SPFH domain, Band 7 family protein
E6P07_09440	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
E6P07_09445	ENOG4105KXW	Ferredoxin
E6P07_09450	ENOG4105U82	Ferredoxin
E6P07_09455	ENOG41065RQ	ADP-ribosylation crystallin J1
E6P07_09460	ENOG4108K8Z	nad( )--dinitrogen-reductase ADP-d-ribosyltransferase
E6P07_09465	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
E6P07_09470	ENOG4105D0B	Nitrogenase protein alpha chain
E6P07_09475	ENOG4105CY9	nitrogenase molybdenum-iron protein beta chain
E6P07_09485	ENOG4107IVC	4Fe-4S ferredoxin, iron-sulfur binding
E6P07_09490	ENOG4105FZE	dinitrogenase iron-molybdenum cofactor biosynthesis
E6P07_09505	ENOG4105D0B	Nitrogenase protein alpha chain
E6P07_09510	ENOG4105DK8	Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN
E6P07_09515	ENOG4108UR2	Nitrogen fixation protein NifX
E6P07_09525	ENOG4108VQE	nitrogen fixation protein
E6P07_09530	ENOG4105WCA	Ferredoxin
E6P07_09535	ENOG4108JUA	Transcriptional regulator
E6P07_09540	ENOG4105DS4	PAS PAC sensor Signal transduction histidine kinase
E6P07_09545	ENOG4105DGN	Electron transport complex
E6P07_09550	ENOG4108R3D	Electron transport complex
E6P07_09555	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
E6P07_09560	ENOG4105D6A	Electron transport complex
E6P07_09565	ENOG4108UQQ	Electron transport complex
E6P07_09570	ENOG4108E8M	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
E6P07_09575	ENOG4105VDB	UPF0125 protein
E6P07_09580	ENOG4105XV5	nifz family
E6P07_09590	ENOG410605C	May protect the nitrogenase Fe-Mo protein from oxidative damage (By similarity)
E6P07_09595	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E6P07_09630	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
E6P07_09635	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
E6P07_09645	ENOG4105EPW	hflc protein
E6P07_09650	ENOG4107QJR	hflk protein
E6P07_09655	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
E6P07_09660	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
E6P07_09665	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
E6P07_09670	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
E6P07_09675	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
E6P07_09680	ENOG4105K8N	protein family UPF0079, ATPase
E6P07_09685	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
E6P07_09695	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
E6P07_09700	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
E6P07_09710	ENOG4105C7F	AcnD-accessory protein PrpF
E6P07_09715	ENOG4108I0Z	Aconitate hydratase
E6P07_09750	ENOG4105KB2	stringent starvation protein b
E6P07_09755	ENOG4107MKT	Stringent starvation protein a
E6P07_09760	ENOG4105EIX	cytochrome c1
E6P07_09765	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
E6P07_09770	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
E6P07_09775	ENOG4107QNR	UPF0135 protein
E6P07_09785	ENOG4105CHR	reductase
E6P07_09790	ENOG41069CB	phasin family
E6P07_09795	ENOG4108NVM	synthesis repressor PhaR
E6P07_09800	ENOG4105CHU	acetyl-coa acetyltransferase
E6P07_09805	ENOG4108U4D	synthase) subunit
E6P07_09810	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
E6P07_09825	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
E6P07_09830	ENOG4108HGY	Proline imino-peptidase
E6P07_09835	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
E6P07_09840	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E6P07_09845	ENOG4105D98	threonine synthase
E6P07_09855	ENOG4107QN1	sodium solute
E6P07_09860	ENOG4106TD9	Diguanylate cyclase
E6P07_09865	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
E6P07_09870	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
E6P07_09880	ENOG4105F8C	transglutaminase domain-containing protein
E6P07_09885	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
E6P07_09900	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
E6P07_09925	ENOG4108PXI	ErfK YbiS YcfS YnhG
E6P07_09930	ENOG4106J5J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
E6P07_09935	ENOG4108UUM	single-stranded DNA-binding protein
E6P07_09940	ENOG4107RDB	Major Facilitator
E6P07_09945	ENOG4105BZU	Histidine kinase
E6P07_09955	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E6P07_09970	ENOG4105C8Q	Methyl-accepting chemotaxis
E6P07_10015	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E6P07_10025	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
E6P07_10035	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
E6P07_10040	ENOG41076HS	cation diffusion facilitator family transporter
E6P07_10050	ENOG4105D7V	transposase
E6P07_10055	ENOG4105C5F	glutamine synthetase
E6P07_10065	ENOG4105CUX	Signal transduction histidine kinase
E6P07_10070	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E6P07_10080	ENOG4105CAS	nag kinase
E6P07_10085	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
E6P07_10090	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
E6P07_10095	ENOG4105W5Q	DNA repair protein (RadC
E6P07_10100	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
E6P07_10110	ENOG4105D52	delta-aminolevulinic acid dehydratase
E6P07_10120	ENOG4105BZU	Histidine kinase
E6P07_10125	ENOG4108V9Q	carbonic anhydrase
E6P07_10145	ENOG4105CQ0	ABC transporter
E6P07_10155	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
E6P07_10160	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
E6P07_10165	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
E6P07_10170	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
E6P07_10180	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
E6P07_10185	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
E6P07_10195	ENOG4105BZU	Histidine kinase
E6P07_10235	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E6P07_10240	ENOG4105BZU	Histidine kinase
E6P07_10245	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E6P07_10250	ENOG4105E0F	Histidine kinase
E6P07_10255	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
E6P07_10260	ENOG4107Y49	methyltransferase
E6P07_10270	ENOG4105CQS	hydrogenase expression formation protein HypD
E6P07_10275	ENOG4105C45	hydrogenase expression formation protein (HypE)
E6P07_10285	ENOG4105DUM	transcriptional regulator, lysR family
E6P07_10295	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
E6P07_10300	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
E6P07_10305	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
E6P07_10310	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
E6P07_10315	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
E6P07_10320	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
E6P07_10335	ENOG4105C03	ribonuclease
E6P07_10340	ENOG4108Z03	MAF-like protein
E6P07_10345	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
E6P07_10355	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
E6P07_10365	ENOG4105BZS	acriflavin resistance protein
E6P07_10400	ENOG4108Z20	Acyl-transferase
E6P07_10445	ENOG4105D5G	Transposase
E6P07_10450	ENOG4105E0Y	RtcB Protein
E6P07_10460	ENOG4108Z33	Thiol disulfide Interchange Protein
E6P07_10465	ENOG4105XCI	PucC protein
E6P07_10520	ENOG4105EB3	Histidine kinase
E6P07_10525	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
E6P07_10535	ENOG4105DAX	Pfam:DUF2983
E6P07_10570	ENOG4105EAC	phosphoserine phosphatase
E6P07_10575	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
E6P07_10580	ENOG4105CCT	upf0313 protein
E6P07_10585	ENOG4105E14	MotA TolQ exbB proton channel
E6P07_10590	ENOG4106VK6	Flagellar motor protein
E6P07_10600	ENOG4105BZS	acriflavin resistance protein
E6P07_10620	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
E6P07_10630	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
E6P07_10645	ENOG4105DZ2	Transcriptional regulator
E6P07_10650	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
E6P07_10655	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E6P07_10660	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
E6P07_10665	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
E6P07_10670	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
E6P07_10685	ENOG4107PE3	Mammalian cell entry related domain protein
E6P07_10690	ENOG4105CY3	ABC transporter, permease
E6P07_10695	ENOG4105DHJ	ABC, transporter
E6P07_10700	ENOG4105C2X	Arabinose 5-phosphate isomerase
E6P07_10705	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
E6P07_10720	ENOG4108IUZ	ABC transporter
E6P07_10725	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E6P07_10730	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
E6P07_10735	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
E6P07_10745	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
E6P07_10755	ENOG41080Z8	PHOSPHOCARRIER protein
E6P07_10760	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
E6P07_10765	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
E6P07_10770	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
E6P07_10775	ENOG4105DFF	Rod shape-determining protein mreb
E6P07_10780	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
E6P07_10785	ENOG4105VQ7	Rod shape-determining protein MreD
E6P07_10790	ENOG4105CJN	penicillin-binding protein
E6P07_10795	ENOG4105CNI	cell division protein FtsW
E6P07_10805	ENOG4105DZ1	carboxypeptidase
E6P07_10815	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
E6P07_10830	ENOG4105BZU	Histidine kinase
E6P07_10845	ENOG41080T7	secreted protein
E6P07_10855	ENOG4105BZU	Histidine kinase
E6P07_10860	ENOG4107QZ7	Cellulose synthase catalytic subunit
E6P07_10865	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
E6P07_10870	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
E6P07_10875	ENOG4106H78	methyltransferase
E6P07_10890	ENOG4105DZR	Type I site-specific deoxyribonuclease
E6P07_10895	ENOG41090HT	Inherit from COG: transposase
E6P07_10905	ENOG4105EKX	Restriction modification system DNA (Specificity
E6P07_10910	ENOG4107R3N	Filamentation induced by cAMP protein fic
E6P07_10915	ENOG4105CB5	ATP-dependent DNA helicase recG
E6P07_10920	ENOG4105CVR	type I restriction-modification system
E6P07_10925	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
E6P07_10930	ENOG4105CAK	Cell division ATP-binding protein ftsE
E6P07_10935	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
E6P07_10945	ENOG4105VZ9	UPF0235 protein
E6P07_10950	ENOG4108VIA	integral membrane protein
E6P07_10955	ENOG4105II7	pyrroline-5-carboxylate reductase
E6P07_10965	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
E6P07_10980	ENOG41060M0	Crispr-associated protein, cse4 family
E6P07_11005	ENOG4105DFA	alanine racemase domain protein
E6P07_11010	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
E6P07_11015	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
E6P07_11020	ENOG4108Z9W	Outer membrane porin
E6P07_11025	ENOG4105E66	phosphoriboisomerase A
E6P07_11030	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
E6P07_11040	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
E6P07_11055	ENOG4107RAQ	aminopeptidase
E6P07_11060	ENOG4105D0A	hydroxylase
E6P07_11065	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
E6P07_11070	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
E6P07_11075	ENOG4105F0N	pyrophosphate phospho-hydrolase
E6P07_11080	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E6P07_11085	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
E6P07_11090	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
E6P07_11095	ENOG4107QRS	glycosyltransferase group 2 family protein
E6P07_11110	ENOG4108V3W	Chemotaxis protein, CheW
E6P07_11115	ENOG4105ER2	Ompa motb domain protein
E6P07_11120	ENOG4105E14	MotA TolQ exbB proton channel
E6P07_11125	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E6P07_11130	ENOG4105CBS	Chea signal transduction histidine kinase
E6P07_11135	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
E6P07_11140	ENOG4108VYJ	response regulator receiver protein
E6P07_11145	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E6P07_11150	ENOG4107R21	site-determining protein
E6P07_11155	ENOG4105FZW	flagellar biosynthesis regulator FlhF
E6P07_11160	ENOG4105D7B	Flagellar biosynthesis protein flha
E6P07_11165	ENOG4105D00	flagellar biosynthetic protein flhB
E6P07_11170	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
E6P07_11175	ENOG4105VS8	Flagellar biosynthetic protein fliq
E6P07_11180	ENOG4105CN7	Flagellar biosynthetic protein FliP
E6P07_11185	ENOG4105VTB	flagellar biosynthesis protein fliO
E6P07_11190	ENOG4105DD5	Flagellar motor switch protein
E6P07_11195	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
E6P07_11215	ENOG4108JIR	Flagellum-specific ATP synthase
E6P07_11225	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
E6P07_11230	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
E6P07_11235	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
E6P07_11255	ENOG4107RD7	Flagellar Motor Protein, MotA
E6P07_11275	ENOG4105E7D	Protein of unknown function (DUF3375)
E6P07_11340	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E6P07_11365	ENOG4105VUH	addiction module killer protein
E6P07_11380	ENOG41060JE	PilT protein domain protein
E6P07_11400	ENOG4105CC0	LysR family Transcriptional regulator
E6P07_11470	ENOG4105EY8	ABC transporter
E6P07_11500	ENOG4105K4I	Scp-like extracellular
E6P07_11505	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
E6P07_11540	ENOG4108JJ6	Type I secretion system ATPase
E6P07_11560	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
E6P07_11575	ENOG4107QP8	phosphohexose isomerase
E6P07_11600	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
E6P07_11605	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
E6P07_11610	ENOG4105C4K	Nad synthetase
E6P07_11635	ENOG4105C59	p-type ATPase
E6P07_11645	ENOG4105C58	cytochrome c oxidase accessory protein ccog
E6P07_11650	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
E6P07_11665	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
E6P07_11670	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E6P07_11675	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
E6P07_11680	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
E6P07_11690	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
E6P07_11695	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
E6P07_11700	ENOG4105CJR	Integral membrane protein (MviN
E6P07_11705	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E6P07_11710	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E6P07_11715	ENOG4105CTB	Polyprenyl synthetase
E6P07_11720	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
E6P07_11725	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
E6P07_11730	ENOG4105EXN	Sulfate transport protein CysZ
E6P07_11745	ENOG4105HF0	Membrane
E6P07_11755	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E6P07_11760	ENOG4105M00	molybdopterin converting factor, subunit 1
E6P07_11780	ENOG4105CEV	competence damage-inducible protein
E6P07_11790	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
E6P07_11800	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E6P07_11805	ENOG4105D60	lipoprotein releasing system transmembrane protein
E6P07_11840	ENOG4107RJX	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
E6P07_11845	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
E6P07_11850	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
E6P07_11860	ENOG4105KA7	cytochrome C
E6P07_11865	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
E6P07_11870	ENOG4105K63	Thioredoxin
E6P07_11890	ENOG4108W63	CRP FNR family transcriptional regulator
E6P07_11905	ENOG4105VXR	cytoplasmic protein
E6P07_11915	ENOG4105XFK	Ferrous iron transport protein A
E6P07_11930	ENOG4105D65	subunit l
E6P07_11935	ENOG4108ZE9	Monovalent cation H antiporter subunit C
E6P07_11940	ENOG4107R4Z	monovalent cation h antiporter subunit d
E6P07_11945	ENOG4105SC1	monovalent cation H antiporter subunit E
E6P07_11950	ENOG4105W4C	monovalent cation H antiporter subunit F
E6P07_11955	ENOG4105KJM	monovalent cation h antiporter subunit g
E6P07_11960	ENOG4108ZAF	Molybdopterin
E6P07_11985	ENOG4105GN9	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
E6P07_11990	ENOG4108TGR	phosphatase
E6P07_11995	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
E6P07_12000	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
E6P07_12005	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
E6P07_12015	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
E6P07_12030	ENOG4105N42	UPF0307 protein
E6P07_12040	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
E6P07_12045	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
E6P07_12055	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E6P07_12065	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
E6P07_12075	ENOG4105C4R	Atp-dependent dna helicase
E6P07_12080	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
E6P07_12085	ENOG4105CSA	Coproporphyrinogen iii oxidase
E6P07_12090	ENOG4105VFB	Binds the 23S rRNA (By similarity)
E6P07_12100	ENOG4105C6K	Malic enzyme
E6P07_12105	ENOG4105BZN	citrate synthase
E6P07_12135	ENOG4105E4G	Type IV pilus
E6P07_12140	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
E6P07_12145	ENOG4105D49	3-dehydroquinate synthase
E6P07_12155	ENOG4107QMP	dna polymerase iii subunits gamma and tau
E6P07_12160	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
E6P07_12165	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
E6P07_12175	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
E6P07_12180	ENOG4107QMS	site-determining protein
E6P07_12185	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
E6P07_12190	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
E6P07_12195	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
E6P07_12200	ENOG4105CHM	Aminotransferase
E6P07_12205	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
E6P07_12225	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
E6P07_12230	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
E6P07_12235	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
E6P07_12240	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
E6P07_12245	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
E6P07_12250	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E6P07_12255	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E6P07_12260	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E6P07_12265	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
E6P07_12275	ENOG4105FA0	parb-like partition protein
E6P07_12280	ENOG4107QJE	Chromosome Partitioning Protein
E6P07_12285	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
E6P07_12300	ENOG4105BZU	Histidine kinase
E6P07_12305	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
E6P07_12310	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
E6P07_12325	ENOG4107QYG	anthranilate phosphoribosyltransferase
E6P07_12330	ENOG4105VQD	rieske 2fe-2S domain-containing protein
E6P07_12355	ENOG4105D9P	serine threonine protein kinase
E6P07_12360	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
E6P07_12365	ENOG4108VYJ	response regulator receiver protein
E6P07_12370	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
E6P07_12375	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
E6P07_12380	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
E6P07_12385	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
E6P07_12390	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
E6P07_12395	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
E6P07_12400	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
E6P07_12405	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
E6P07_12410	ENOG4107RZZ	dna polymerase iii epsilon subunit
E6P07_12415	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E6P07_12420	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
E6P07_12425	ENOG4105E9H	Lytic Murein transglycosylase
E6P07_12435	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
E6P07_12440	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
E6P07_12450	ENOG4105C8U	phosphate abc transporter
E6P07_12465	ENOG4105BZF	Glycosyl transferase (Group 1
E6P07_12480	ENOG4108ZF3	Phosphatase
E6P07_12485	ENOG4105T95	Thiol disulfide interChange protein
E6P07_12490	ENOG4108VPT	UPF0234 protein
E6P07_12495	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E6P07_12500	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
E6P07_12505	ENOG4108ZZ3	UPF0260 protein
E6P07_12525	ENOG4105DZP	Membrane-associated zinc metalloprotease
E6P07_12530	ENOG4105CPK	Glycosyl transferase (Group 1
E6P07_12540	ENOG4105E4C	Lytic transglycosylase catalytic
E6P07_12560	ENOG4105C8N	cysteinyl-tRNA synthetase
E6P07_12565	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
E6P07_12570	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
E6P07_12595	ENOG4107RSS	Hydrogenase accessory protein HypB
E6P07_12625	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
E6P07_12630	ENOG4105Q36	FHA domain containing protein
E6P07_12645	ENOG4105CPK	Glycosyl transferase (Group 1
E6P07_12655	ENOG4107XU6	Glycosyl transferase (Group 1
E6P07_12660	ENOG4105DSY	exodeoxyribonuclease V, gamma
E6P07_12665	ENOG4107QKA	exodeoxyribonuclease V beta
E6P07_12675	ENOG4107QYX	exodeoxyribonuclease v alpha
E6P07_12680	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
E6P07_12685	ENOG4105E2X	shikimate dehydrogenase
E6P07_12690	ENOG4105C25	Primosomal protein n'
E6P07_12695	ENOG4105C75	arginyL-tRNA synthetase
E6P07_12705	ENOG4107QHQ	amino acid
E6P07_12715	ENOG4105CE1	Ferrous iron transport protein b
E6P07_12720	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
E6P07_12725	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
E6P07_12735	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
E6P07_12740	ENOG4105VG0	50S ribosomal protein l34
E6P07_12745	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
E6P07_12750	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
E6P07_12755	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
E6P07_12765	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E6P07_12780	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E6P07_12820	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E6P07_12830	ENOG4105P4J	Allophanate hydrolase, subunit 1
E6P07_12840	ENOG4105E7W	lamb ycsf family protein
E6P07_12850	ENOG4105C3K	feS assembly ATPase SufC
E6P07_12860	ENOG4105VG1	fes assembly suf system protein
E6P07_12875	ENOG4105C0D	helicase
E6P07_12880	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
E6P07_12895	ENOG4108J2R	molybdopterin oxidoreductase
E6P07_12905	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
E6P07_12915	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
E6P07_12940	ENOG4105CAQ	asparagine synthetase
E6P07_12945	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
E6P07_12950	ENOG4107R7Y	intracellular protease Pfpi family
E6P07_12995	ENOG4105E2K	Glycosyl transferase (Group 1
E6P07_13010	ENOG4105E2K	Glycosyl transferase (Group 1
E6P07_13020	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
E6P07_13030	ENOG4105CRQ	synthase (Component I)
E6P07_13035	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E6P07_13045	ENOG4105CPC	Aldo Keto reductase
E6P07_13050	ENOG4105K6T	rare lipoprotein A
E6P07_13065	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E6P07_13070	ENOG4105JJR	Histidine kinase
E6P07_13075	ENOG4105D78	K07001 NTE family protein
E6P07_13080	ENOG4105EHZ	conserved protein UCP016719
E6P07_13085	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
E6P07_13095	ENOG4105VFU	Rna-binding protein
E6P07_13105	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
E6P07_13110	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
E6P07_13125	ENOG4107QZT	geranylgeranyl reductase
E6P07_13130	ENOG4105DB3	bacteriochlorophyll chlorophyll a synthase
E6P07_13135	ENOG4105D4D	transcriptional regulator
E6P07_13140	ENOG4108VJI	2-vinyl bacteriochlorophyllide hydratase
E6P07_13145	ENOG4105C78	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
E6P07_13150	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
E6P07_13155	ENOG4105CTK	cobaltochelatase, cobn subunit
E6P07_13160	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
E6P07_13165	ENOG4108MIC	Mg-protoporphyrin IX methyl transferase
E6P07_13190	ENOG4105D4P	Coproporphyrinogen iii oxidase
E6P07_13200	ENOG4105CEY	Amp-dependent synthetase and ligase
E6P07_13210	ENOG4105DZS	Phenylacetate-CoA ligase
E6P07_13220	ENOG4105DZS	Phenylacetate-CoA ligase
E6P07_13235	ENOG4105BZU	Histidine kinase
E6P07_13240	ENOG4105BZU	Histidine kinase
E6P07_13250	ENOG4107YTP	response regulator receiver protein
E6P07_13255	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E6P07_13260	ENOG4105CZX	twitching motility protein
E6P07_13265	ENOG4105CZX	twitching motility protein
E6P07_13270	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
E6P07_13275	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
E6P07_13280	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
E6P07_13290	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
E6P07_13300	ENOG4105C8Q	Methyl-accepting chemotaxis
E6P07_13305	ENOG4108VYJ	response regulator receiver protein
E6P07_13315	ENOG4105CBS	Chea signal transduction histidine kinase
E6P07_13320	ENOG4107YTP	response regulator receiver protein
E6P07_13325	ENOG4105BZU	Histidine kinase
E6P07_13335	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E6P07_13340	ENOG4108V3W	Chemotaxis protein, CheW
E6P07_13345	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
E6P07_13350	ENOG4105CV6	ABC transporter, permease
E6P07_13355	ENOG4108I0Y	(ABC) transporter
E6P07_13360	ENOG4108UJV	acyl-CoA thioesterase i
E6P07_13370	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E6P07_13375	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E6P07_13380	ENOG4105VIE	preprotein translocase, subunit YajC
E6P07_13390	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
E6P07_13395	ENOG4105D1F	ATP-binding protein
E6P07_13410	ENOG41090A1	ferritin
E6P07_13430	ENOG4105BZU	Histidine kinase
E6P07_13450	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
E6P07_13455	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E6P07_13460	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E6P07_13470	ENOG41073TP	transcriptional regulator
E6P07_13475	ENOG4105CR4	methylisocitrate lyase
E6P07_13480	ENOG4105BZN	citrate synthase
E6P07_13490	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E6P07_13495	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
E6P07_13500	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
E6P07_13515	ENOG4105VCQ	rubredoxin
E6P07_13525	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
E6P07_13530	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
E6P07_13535	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
E6P07_13540	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)