locus-tag	class	description
TBCH5v1_0001	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TBCH5v1_0003	COG0511	ligase activity, forming carbon-carbon bonds
TBCH5v1_0003	COG5016	pyruvate
TBCH5v1_0004	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
TBCH5v1_0011	COG0281	malic enzyme
TBCH5v1_0012	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
TBCH5v1_0013	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
TBCH5v1_0014	COG1024	Enoyl-CoA hydratase
TBCH5v1_0018	COG1061	Type III restriction enzyme res subunit
TBCH5v1_0025	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
TBCH5v1_0033	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
TBCH5v1_0061	COG4608	Belongs to the ABC transporter superfamily
TBCH5v1_0062	COG0444	Belongs to the ABC transporter superfamily
TBCH5v1_0064	COG0601	transmembrane transport
TBCH5v1_0065	COG0747	negative chemotaxis
TBCH5v1_0070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TBCH5v1_0083	COG0129	dihydroxy-acid dehydratase activity
TBCH5v1_0098	COG1473	amidohydrolase
TBCH5v1_0099	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TBCH5v1_0102	COG0490	domain, Protein
TBCH5v1_0102	COG0471	metal ion transport
TBCH5v1_0103	COG4670	ketone body catabolic process
TBCH5v1_0104	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TBCH5v1_0106	COG5016	pyruvate
TBCH5v1_0106	COG0511	ligase activity, forming carbon-carbon bonds
TBCH5v1_0107	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
TBCH5v1_0108	COG0517	IMP dehydrogenase activity
TBCH5v1_0108	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
TBCH5v1_0109	COG0460	homoserine dehydrogenase
TBCH5v1_0114	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TBCH5v1_0116	COG0089	rRNA binding
TBCH5v1_0117	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TBCH5v1_0118	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TBCH5v1_0120	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TBCH5v1_0121	COG0255	Belongs to the universal ribosomal protein uL29 family
TBCH5v1_0122	COG0023	Translation Initiation Factor
TBCH5v1_0124	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
TBCH5v1_0125	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TBCH5v1_0126	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
TBCH5v1_0128	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TBCH5v1_0130	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TBCH5v1_0131	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TBCH5v1_0134	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
TBCH5v1_0135	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TBCH5v1_0136	COG1841	ribosomal large subunit assembly
TBCH5v1_0137	COG0200	Binds to the 23S rRNA
TBCH5v1_0142	COG1102	Psort location Cytoplasmic, score
TBCH5v1_0145	COG1598	PFAM Uncharacterised protein family UPF0150
TBCH5v1_0147	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TBCH5v1_0150	COG2813	Specifically methylates the guanine in position
TBCH5v1_0151	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TBCH5v1_0152	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TBCH5v1_0153	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TBCH5v1_0156	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TBCH5v1_0157	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TBCH5v1_0160	COG0148	phosphopyruvate hydratase activity
TBCH5v1_0161	COG0052	Belongs to the universal ribosomal protein uS2 family
TBCH5v1_0162	COG1355	regulation of microtubule-based process
TBCH5v1_0168	COG2361	Protein of unknown function DUF86
TBCH5v1_0176	COG1304	FMN binding
TBCH5v1_0180	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
TBCH5v1_0181	COG0142	geranyltranstransferase activity
TBCH5v1_0184	COG0495	leucyl-tRNA aminoacylation
TBCH5v1_0188	COG0626	cystathionine gamma-synthase activity
TBCH5v1_0191	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
TBCH5v1_0192	COG0527	aspartate kinase activity
TBCH5v1_0193	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
TBCH5v1_0196	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
TBCH5v1_0200	COG1185	polyribonucleotide nucleotidyltransferase activity
TBCH5v1_0212	COG0359	binds to the 23S rRNA
TBCH5v1_0212	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
TBCH5v1_0215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TBCH5v1_0215	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TBCH5v1_0216	COG0667	Aldo Keto reductase
TBCH5v1_0229	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
TBCH5v1_0232	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
TBCH5v1_0237	COG0717	Belongs to the dCTP deaminase family
TBCH5v1_0240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TBCH5v1_0243	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TBCH5v1_0249	COG0058	SHG alpha-glucan phosphorylase activity
TBCH5v1_0255	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TBCH5v1_0258	COG2271	Major facilitator Superfamily
TBCH5v1_0259	COG2211	Major facilitator Superfamily
TBCH5v1_0260	COG0584	glycerophosphoryl diester phosphodiesterase
TBCH5v1_0261	COG0584	glycerophosphoryl diester phosphodiesterase
TBCH5v1_0268	COG0579	oxidoreductase
TBCH5v1_0280	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TBCH5v1_0287	COG0085	RNA polymerase activity
TBCH5v1_0288	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TBCH5v1_0289	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TBCH5v1_0293	COG0049	tRNA binding
TBCH5v1_0294	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
TBCH5v1_0297	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TBCH5v1_0298	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
TBCH5v1_0300	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TBCH5v1_0304	COG0477	Major facilitator Superfamily
TBCH5v1_0307	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TBCH5v1_0310	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TBCH5v1_0319	COG1695	Transcriptional regulator
TBCH5v1_0326	COG1554	hydrolase, family 65, central catalytic
TBCH5v1_0331	COG3833	ABC-type maltose transport systems, permease component
TBCH5v1_0332	COG3842	ATPase activity
TBCH5v1_0336	COG0003	Pfam Anion-transporting ATPase
TBCH5v1_0338	COG1966	Carbon starvation protein
TBCH5v1_0339	COG5016	pyruvate
TBCH5v1_0339	COG0511	ligase activity, forming carbon-carbon bonds
TBCH5v1_0340	COG1830	Aldolase
TBCH5v1_0341	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
TBCH5v1_0341	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
TBCH5v1_0345	COG1872	DUF167
TBCH5v1_0347	COG0423	glycine-tRNA ligase activity
TBCH5v1_0351	COG0534	Mate efflux family protein
TBCH5v1_0355	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
TBCH5v1_0357	COG0006	proline dipeptidase activity
TBCH5v1_0361	COG0709	Synthesizes selenophosphate from selenide and ATP
TBCH5v1_0365	COG1918	ferrous iron import across plasma membrane
TBCH5v1_0365	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
TBCH5v1_0367	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TBCH5v1_0369	COG0163	prenyltransferase activity
TBCH5v1_0370	COG1522	sequence-specific DNA binding
TBCH5v1_0374	COG0012	GTP binding
TBCH5v1_0385	COG0312	modulator of DNA gyrase
TBCH5v1_0386	COG0312	modulator of DNA gyrase
TBCH5v1_0390	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TBCH5v1_0397	COG0243	molybdopterin cofactor binding
TBCH5v1_0399	COG0450	alkyl hydroperoxide reductase
TBCH5v1_0402	COG1013	pyruvate-flavodoxin oxidoreductase activity
TBCH5v1_0403	COG0450	alkyl hydroperoxide reductase
TBCH5v1_0404	COG0426	domain, Protein
TBCH5v1_0404	COG1773	rubredoxin
TBCH5v1_0410	COG1592	Rubrerythrin
TBCH5v1_0411	COG1773	rubredoxin
TBCH5v1_0412	COG2033	superoxide reductase activity
TBCH5v1_0428	COG0557	exoribonuclease II activity
TBCH5v1_0433	COG1185	polyribonucleotide nucleotidyltransferase activity
TBCH5v1_0438	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
TBCH5v1_0446	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TBCH5v1_0453	COG0252	asparaginase activity
TBCH5v1_0454	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TBCH5v1_0458	COG2894	cell division
TBCH5v1_0459	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TBCH5v1_0460	COG1063	alcohol dehydrogenase
TBCH5v1_0461	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
TBCH5v1_0466	COG0101	tRNA pseudouridine synthase activity
TBCH5v1_0467	COG0556	nucleotide-excision repair
TBCH5v1_0469	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TBCH5v1_0471	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TBCH5v1_0472	COG0083	homoserine kinase activity
TBCH5v1_0473	COG0527	aspartate kinase activity
TBCH5v1_0475	COG3959	Transketolase, thiamine diphosphate binding domain
TBCH5v1_0476	COG3958	Transketolase
TBCH5v1_0477	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TBCH5v1_0479	COG0710	3-dehydroquinate dehydratase activity
TBCH5v1_0485	COG0436	Aminotransferase
TBCH5v1_0487	COG0560	Phosphoserine phosphatase
TBCH5v1_0491	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TBCH5v1_0492	COG0140	phosphoribosyl-ATP diphosphatase activity
TBCH5v1_0492	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TBCH5v1_0493	COG0107	imidazoleglycerol-phosphate synthase activity
TBCH5v1_0495	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
TBCH5v1_0496	COG0131	Imidazoleglycerol-phosphate dehydratase
TBCH5v1_0498	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TBCH5v1_0502	COG2267	carboxylic ester hydrolase activity
TBCH5v1_0503	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
TBCH5v1_0511	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
TBCH5v1_0513	COG3842	ATPase activity
TBCH5v1_0514	COG1178	ABC-type Fe3 transport system permease component
TBCH5v1_0516	COG2971	BadF BadG BcrA BcrD
TBCH5v1_0526	COG4821	SIS domain
TBCH5v1_0534	COG2403	cyclic 2,3-diphosphoglycerate synthetase activity
TBCH5v1_0535	COG0725	ABC transporter, periplasmic molybdate-binding protein
TBCH5v1_0536	COG4149	molybdate abc transporter
TBCH5v1_0537	COG3842	ATPase activity
TBCH5v1_0544	COG1201	RNA secondary structure unwinding
TBCH5v1_0549	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TBCH5v1_0551	COG1618	nucleotide phosphatase activity, acting on free nucleotides
TBCH5v1_0552	COG1120	ATPase activity
TBCH5v1_0553	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TBCH5v1_0556	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TBCH5v1_0560	COG1013	pyruvate-flavodoxin oxidoreductase activity
TBCH5v1_0561	COG0674	pyruvate-flavodoxin oxidoreductase activity
TBCH5v1_0561	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TBCH5v1_0563	COG1013	pyruvate-flavodoxin oxidoreductase activity
TBCH5v1_0564	COG0674	pyruvate-flavodoxin oxidoreductase activity
TBCH5v1_0564	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TBCH5v1_0569	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TBCH5v1_0570	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TBCH5v1_0573	COG0051	transcription antitermination factor activity, RNA binding
TBCH5v1_0580	COG1131	(ABC) transporter
TBCH5v1_0582	COG0393	Putative heavy-metal-binding
TBCH5v1_0583	COG0315	cyclic pyranopterin monophosphate synthase activity
TBCH5v1_0585	COG1193	negative regulation of DNA recombination
TBCH5v1_0587	COG0515	serine threonine protein kinase
TBCH5v1_0598	COG1078	dGTPase activity
TBCH5v1_0600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TBCH5v1_0605	COG0501	Belongs to the peptidase M48B family
TBCH5v1_0606	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
TBCH5v1_0608	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
TBCH5v1_0610	COG1515	deoxyribonuclease V activity
TBCH5v1_0614	COG0569	domain protein
TBCH5v1_0617	COG1476	TRANSCRIPTIONal
TBCH5v1_0620	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
TBCH5v1_0622	COG1492	cobalamin metabolic process
TBCH5v1_0623	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TBCH5v1_0624	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
TBCH5v1_0629	COG1573	uracil-dna glycosylase
TBCH5v1_0638	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
TBCH5v1_0640	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TBCH5v1_0642	COG0437	4 iron, 4 sulfur cluster binding
TBCH5v1_0645	COG0651	ATP synthesis coupled electron transport
TBCH5v1_0647	COG1006	Multisubunit Na H antiporter MnhC subunit
TBCH5v1_0652	COG3260	NADH ubiquinone oxidoreductase 20
TBCH5v1_0653	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TBCH5v1_0654	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
TBCH5v1_0654	COG3261	NADH dehydrogenase
TBCH5v1_0655	COG0650	Formate hydrogenlyase subunit 4
TBCH5v1_0656	COG0651	ATP synthesis coupled electron transport
TBCH5v1_0657	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TBCH5v1_0658	COG0437	4 iron, 4 sulfur cluster binding
TBCH5v1_0659	COG0243	molybdopterin cofactor binding
TBCH5v1_0662	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
TBCH5v1_0667	COG0840	transmembrane signaling receptor activity
TBCH5v1_0670	COG1201	RNA secondary structure unwinding
TBCH5v1_0670	COG1201	RNA secondary structure unwinding
TBCH5v1_0674	COG1505	serine-type exopeptidase activity
TBCH5v1_0675	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
TBCH5v1_0679	COG1047	Peptidyl-prolyl cis-trans
TBCH5v1_0680	COG0215	cysteine-tRNA ligase activity
TBCH5v1_0685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TBCH5v1_0686	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
TBCH5v1_0689	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TBCH5v1_0693	COG0803	Belongs to the bacterial solute-binding protein 9 family
TBCH5v1_0698	COG1744	ABC transporter substrate-binding protein PnrA-like
TBCH5v1_0700	COG0351	phosphomethylpyrimidine kinase
TBCH5v1_0701	COG0352	thiamine-phosphate diphosphorylase activity
TBCH5v1_0702	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
TBCH5v1_0705	COG0552	protein localization to endoplasmic reticulum
TBCH5v1_0709	COG2205	protein histidine kinase activity
TBCH5v1_0714	COG1469	GTP cyclohydrolase I activity
TBCH5v1_0717	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TBCH5v1_0723	COG0616	signal peptide processing
TBCH5v1_0725	COG0628	permease
TBCH5v1_0727	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TBCH5v1_0728	COG1518	maintenance of DNA repeat elements
TBCH5v1_0731	COG1203	CRISPR-associated helicase, Cas3
TBCH5v1_0737	COG1216	Glycosyl transferase, family 2
TBCH5v1_0745	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TBCH5v1_0746	COG1993	acr, cog1993
TBCH5v1_0749	COG1794	racemase activity, acting on amino acids and derivatives
TBCH5v1_0751	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TBCH5v1_0752	COG1058	Belongs to the CinA family
TBCH5v1_0752	COG1546	Belongs to the CinA family
TBCH5v1_0753	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TBCH5v1_0759	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TBCH5v1_0760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TBCH5v1_0762	COG0084	hydrolase, TatD family'
TBCH5v1_0765	COG1131	(ABC) transporter
TBCH5v1_0771	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TBCH5v1_0776	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TBCH5v1_0778	COG0644	oxidoreductase
TBCH5v1_0784	COG0563	adenylate kinase activity
TBCH5v1_0786	COG0011	TIGRFAM Protein of
TBCH5v1_0787	COG2226	methyltransferase
TBCH5v1_0790	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TBCH5v1_0795	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TBCH5v1_0797	COG1121	(ABC) transporter
TBCH5v1_0799	COG1121	(ABC) transporter
TBCH5v1_0800	COG1205	dead DEAH box helicase
TBCH5v1_0800	COG1111	helicase
TBCH5v1_0801	COG1739	Uncharacterized protein family UPF0029
TBCH5v1_0809	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TBCH5v1_0818	COG1122	ATPase activity
TBCH5v1_0819	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TBCH5v1_0820	COG0402	S-adenosylhomocysteine deaminase activity
TBCH5v1_0821	COG0024	Methionine aminopeptidase
TBCH5v1_0822	COG0517	IMP dehydrogenase activity
TBCH5v1_0822	COG0516	GMP reductase activity
TBCH5v1_0824	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TBCH5v1_0825	COG1968	undecaprenyl-diphosphatase activity
TBCH5v1_0828	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TBCH5v1_0832	COG0504	CTP synthase activity
TBCH5v1_0840	COG0525	valine-tRNA ligase activity
TBCH5v1_0856	COG0436	Aminotransferase
TBCH5v1_0857	COG2192	nodulation
TBCH5v1_0858	COG0442	prolyl-tRNA aminoacylation
TBCH5v1_0859	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TBCH5v1_0860	COG1363	Peptidase, m42
TBCH5v1_0861	COG0730	response to heat
TBCH5v1_0862	COG0730	response to heat
TBCH5v1_0863	COG0601	transmembrane transport
TBCH5v1_0871	COG0720	synthase
TBCH5v1_0874	COG0312	modulator of DNA gyrase
TBCH5v1_0875	COG0312	modulator of DNA gyrase
TBCH5v1_0901	COG1598	PFAM Uncharacterised protein family UPF0150
TBCH5v1_0926	COG0585	pseudouridine synthase activity
TBCH5v1_0929	COG0017	Asparaginyl-tRNA synthetase
TBCH5v1_0931	COG1418	mRNA catabolic process
TBCH5v1_0936	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
TBCH5v1_0941	COG1110	DNA topoisomerase II activity
TBCH5v1_0949	COG0671	phosphoesterase, PA-phosphatase related
TBCH5v1_0956	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TBCH5v1_0972	COG2414	aldehyde ferredoxin oxidoreductase
TBCH5v1_0979	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TBCH5v1_0982	COG1160	GTP binding
TBCH5v1_0989	COG1832	CoA-binding protein
TBCH5v1_0994	COG2379	hydroxypyruvate reductase
TBCH5v1_0995	COG2610	gluconate transmembrane transporter activity
TBCH5v1_1000	COG1435	thymidine kinase activity
TBCH5v1_1001	COG1850	ribulose-bisphosphate carboxylase activity
TBCH5v1_1006	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TBCH5v1_1010	COG1028	Short-chain dehydrogenase reductase Sdr
TBCH5v1_1011	COG1881	PFAM PEBP family protein
TBCH5v1_1019	COG0475	glutathione-regulated potassium exporter activity
TBCH5v1_1021	COG0822	iron-sulfur transferase activity
TBCH5v1_1023	COG1104	cysteine desulfurase activity
TBCH5v1_1026	COG1151	hydroxylamine reductase activity
TBCH5v1_1028	COG0426	domain, Protein
TBCH5v1_1031	COG0006	proline dipeptidase activity
TBCH5v1_1038	COG0649	NAD binding
TBCH5v1_1040	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TBCH5v1_1041	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TBCH5v1_1043	COG0651	ATP synthesis coupled electron transport
TBCH5v1_1045	COG2111	Na H antiporter
TBCH5v1_1045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TBCH5v1_1047	COG1320	monovalent cation:proton antiporter activity
TBCH5v1_1049	COG1863	multisubunit Na H antiporter MnhE subunit
TBCH5v1_1051	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TBCH5v1_1054	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
TBCH5v1_1060	COG0018	arginyl-trna synthetase
TBCH5v1_1062	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TBCH5v1_1075	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
TBCH5v1_1081	COG1522	sequence-specific DNA binding
TBCH5v1_1082	COG1694	Mazg nucleotide pyrophosphohydrolase
TBCH5v1_1089	COG1067	ATP-dependent peptidase activity
TBCH5v1_1089	COG0470	DNA polymerase III
TBCH5v1_1091	COG1215	transferase activity, transferring glycosyl groups
TBCH5v1_1092	COG0306	phosphate transporter
TBCH5v1_1095	COG0419	ATPase involved in DNA repair
TBCH5v1_1095	COG0419	ATPase involved in DNA repair
TBCH5v1_1097	COG0433	COG0433 Predicted ATPase
TBCH5v1_1099	COG0456	acetyltransferase
TBCH5v1_1099	COG1214	PFAM Peptidase M22, glycoprotease
TBCH5v1_1103	COG0156	8-amino-7-oxononanoate synthase activity
TBCH5v1_1105	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
TBCH5v1_1106	COG2255	four-way junction helicase activity
TBCH5v1_1108	COG2264	protein methyltransferase activity
TBCH5v1_1111	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TBCH5v1_1113	COG3557	Belongs to the UPF0374 family
TBCH5v1_1130	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
TBCH5v1_1131	COG2226	methyltransferase
TBCH5v1_1134	COG1446	asparaginase
TBCH5v1_1135	COG2814	Major facilitator Superfamily
TBCH5v1_1136	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TBCH5v1_1139	COG2271	Major facilitator Superfamily
TBCH5v1_1140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TBCH5v1_1142	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TBCH5v1_1143	COG0546	phosphoglycolate phosphatase activity
TBCH5v1_1145	COG2131	deaminase
TBCH5v1_1146	COG0501	Belongs to the peptidase M48B family
TBCH5v1_1153	COG1085	galactose-1-phosphate uridylyltransferase
TBCH5v1_1155	COG2723	6-phospho-beta-galactosidase activity
TBCH5v1_1162	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TBCH5v1_1164	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TBCH5v1_1175	COG0733	neurotransmitter:sodium symporter activity
TBCH5v1_1176	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TBCH5v1_1178	COG0693	protein deglycase activity
TBCH5v1_1183	COG1765	OsmC-like protein
TBCH5v1_1185	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
TBCH5v1_1187	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TBCH5v1_1193	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
TBCH5v1_1193	COG0517	IMP dehydrogenase activity
TBCH5v1_1196	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TBCH5v1_1197	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TBCH5v1_1197	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TBCH5v1_1200	COG0489	protein tyrosine kinase activity
TBCH5v1_1201	COG0489	protein tyrosine kinase activity
TBCH5v1_1203	COG1342	Belongs to the UPF0251 family
TBCH5v1_1216	COG0513	Belongs to the DEAD box helicase family
TBCH5v1_1219	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
TBCH5v1_1222	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
TBCH5v1_1225	COG2894	cell division
TBCH5v1_1226	COG0330	HflC and HflK could
TBCH5v1_1229	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
TBCH5v1_1236	COG1914	H( )-stimulated, divalent metal cation uptake system
TBCH5v1_1237	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
TBCH5v1_1240	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
TBCH5v1_1241	COG1984	allophanate hydrolase subunit 2
TBCH5v1_1243	COG0371	Dehydrogenase
TBCH5v1_1245	COG0483	inositol monophosphate 1-phosphatase activity
TBCH5v1_1250	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
TBCH5v1_1251	COG2361	Protein of unknown function DUF86
TBCH5v1_1253	COG1196	nuclear chromosome segregation
TBCH5v1_1257	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TBCH5v1_1257	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TBCH5v1_1258	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TBCH5v1_1262	COG2894	cell division
TBCH5v1_1264	COG0367	asparagine synthase
TBCH5v1_1266	COG0297	glycogen (starch) synthase activity
TBCH5v1_1268	COG0009	L-threonylcarbamoyladenylate synthase
TBCH5v1_1276	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
TBCH5v1_1277	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
TBCH5v1_1287	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
TBCH5v1_1292	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TBCH5v1_1300	COG0482	sulfurtransferase activity
TBCH5v1_1310	COG1042	CoA-binding domain protein
TBCH5v1_1310	COG0045	succinate-CoA ligase (ADP-forming) activity
TBCH5v1_1310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TBCH5v1_1315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TBCH5v1_1317	COG0303	'Molybdopterin
TBCH5v1_1320	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TBCH5v1_1328	COG0105	UTP biosynthetic process
TBCH5v1_1331	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TBCH5v1_1332	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TBCH5v1_1333	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TBCH5v1_1334	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TBCH5v1_1343	COG2001	Belongs to the MraZ family
TBCH5v1_1345	COG0137	argininosuccinate synthase activity
TBCH5v1_1346	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TBCH5v1_1346	COG1213	nucleotidyl transferase
TBCH5v1_1347	COG3842	ATPase activity
TBCH5v1_1348	COG0395	ABC-type sugar transport system, permease component
TBCH5v1_1352	COG1199	ATP-dependent helicase activity
TBCH5v1_1355	COG0651	ATP synthesis coupled electron transport
TBCH5v1_1357	COG1006	Multisubunit Na H antiporter MnhC subunit
TBCH5v1_1358	COG2111	Na H antiporter
TBCH5v1_1360	COG1320	monovalent cation:proton antiporter activity
TBCH5v1_1362	COG3260	NADH ubiquinone oxidoreductase 20
TBCH5v1_1363	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TBCH5v1_1364	COG3261	NADH dehydrogenase
TBCH5v1_1364	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
TBCH5v1_1365	COG0650	Formate hydrogenlyase subunit 4
TBCH5v1_1366	COG0651	ATP synthesis coupled electron transport
TBCH5v1_1368	COG0003	Pfam Anion-transporting ATPase
TBCH5v1_1369	COG1151	hydroxylamine reductase activity
TBCH5v1_1370	COG0437	4 iron, 4 sulfur cluster binding
TBCH5v1_1373	COG1489	DNA binding
TBCH5v1_1378	COG0778	Nitroreductase
TBCH5v1_1380	COG0301	tRNA thio-modification
TBCH5v1_1381	COG0301	tRNA thio-modification
TBCH5v1_1383	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TBCH5v1_1392	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TBCH5v1_1392	COG0045	succinate-CoA ligase (ADP-forming) activity
TBCH5v1_1392	COG1042	CoA-binding domain protein
TBCH5v1_1396	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TBCH5v1_1400	COG1131	(ABC) transporter
TBCH5v1_1403	COG0126	phosphoglycerate kinase activity
TBCH5v1_1407	COG3842	ATPase activity
TBCH5v1_1408	COG1178	ABC-type Fe3 transport system permease component
TBCH5v1_1414	COG0513	Belongs to the DEAD box helicase family
TBCH5v1_1417	COG0017	Asparaginyl-tRNA synthetase
TBCH5v1_1418	COG0402	S-adenosylhomocysteine deaminase activity
TBCH5v1_1424	COG0840	transmembrane signaling receptor activity
TBCH5v1_1425	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
TBCH5v1_1428	COG2198	Histidine kinase
TBCH5v1_1428	COG0643	Histidine kinase
TBCH5v1_1429	COG2201	protein-glutamate methylesterase activity
TBCH5v1_1430	COG2201	protein-glutamate methylesterase activity
TBCH5v1_1432	COG3290	protein histidine kinase activity
TBCH5v1_1432	COG0840	transmembrane signaling receptor activity
TBCH5v1_1451	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
TBCH5v1_1466	COG1051	belongs to the nudix hydrolase family
TBCH5v1_1466	COG1056	cytidyltransferase-related domain
TBCH5v1_1477	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
TBCH5v1_1479	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
TBCH5v1_1489	COG1396	sequence-specific DNA binding
TBCH5v1_1492	COG0778	Nitroreductase
TBCH5v1_1500	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
TBCH5v1_1511	COG0588	phosphoglycerate mutase activity
TBCH5v1_1514	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TBCH5v1_1515	COG0071	Belongs to the small heat shock protein (HSP20) family
TBCH5v1_1520	COG2119	membrane
TBCH5v1_1525	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
TBCH5v1_1526	COG1192	Involved in chromosome partitioning
TBCH5v1_1528	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
TBCH5v1_1528	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
TBCH5v1_1530	COG0284	orotidine-5'-phosphate decarboxylase activity
TBCH5v1_1533	COG1793	dna ligase
TBCH5v1_1533	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TBCH5v1_1536	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TBCH5v1_1538	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TBCH5v1_1545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TBCH5v1_1546	COG0183	Belongs to the thiolase family
TBCH5v1_1558	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TBCH5v1_1566	COG2414	aldehyde ferredoxin oxidoreductase
TBCH5v1_1571	COG1028	Short-chain dehydrogenase reductase Sdr
TBCH5v1_1575	COG1141	Ferredoxin
TBCH5v1_1576	COG1141	Ferredoxin
TBCH5v1_1577	COG2151	metal-sulfur cluster biosynthetic enzyme
TBCH5v1_1581	COG1402	creatininase
TBCH5v1_1582	COG0297	glycogen (starch) synthase activity
TBCH5v1_1586	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TBCH5v1_1588	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TBCH5v1_1592	COG0651	ATP synthesis coupled electron transport
TBCH5v1_1597	COG1320	monovalent cation:proton antiporter activity
TBCH5v1_1598	COG2212	antiporter activity
TBCH5v1_1599	COG1863	multisubunit Na H antiporter MnhE subunit
TBCH5v1_1600	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
TBCH5v1_1601	COG0309	Hydrogenase expression formation protein (HypE)
TBCH5v1_1604	COG0489	protein tyrosine kinase activity
TBCH5v1_1621	COG2815	serine threonine protein kinase
TBCH5v1_1621	COG0515	serine threonine protein kinase
TBCH5v1_1622	COG0515	serine threonine protein kinase
TBCH5v1_1622	COG2815	serine threonine protein kinase
TBCH5v1_1624	COG2815	serine threonine protein kinase
TBCH5v1_1624	COG0515	serine threonine protein kinase
TBCH5v1_1625	COG0631	protein serine/threonine phosphatase activity
TBCH5v1_1626	COG0515	serine threonine protein kinase
TBCH5v1_1626	COG2815	serine threonine protein kinase
TBCH5v1_1632	COG1194	a g-specific adenine glycosylase
TBCH5v1_1634	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TBCH5v1_1644	COG2217	Heavy metal translocating P-type atpase
TBCH5v1_1651	COG0626	cystathionine gamma-synthase activity
TBCH5v1_1652	COG2226	methyltransferase
TBCH5v1_1654	COG2217	Heavy metal translocating P-type atpase
TBCH5v1_1655	COG0456	acetyltransferase
TBCH5v1_1656	COG2217	Heavy metal translocating P-type atpase
TBCH5v1_1658	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TBCH5v1_1665	COG0672	)-iron permease
TBCH5v1_1666	COG0450	alkyl hydroperoxide reductase
TBCH5v1_1667	COG1522	sequence-specific DNA binding
TBCH5v1_1672	COG4716	Myosin-crossreactive antigen
TBCH5v1_1673	COG0719	Fe-S assembly protein
TBCH5v1_1675	COG0396	ATPase activity
TBCH5v1_1676	COG0301	tRNA thio-modification
TBCH5v1_1677	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TBCH5v1_1680	COG0778	Nitroreductase
TBCH5v1_1684	COG0432	Pfam Uncharacterised protein family UPF0047
TBCH5v1_1686	COG1992	Thiamine-phosphate synthase
TBCH5v1_1686	COG0351	phosphomethylpyrimidine kinase
TBCH5v1_1687	COG0540	Belongs to the ATCase OTCase family
TBCH5v1_1688	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
TBCH5v1_1692	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TBCH5v1_1695	COG0237	dephospho-CoA kinase activity
TBCH5v1_1706	COG0434	BtpA family
TBCH5v1_1709	COG0312	modulator of DNA gyrase
TBCH5v1_1711	COG0312	modulator of DNA gyrase
TBCH5v1_1715	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TBCH5v1_1721	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TBCH5v1_1722	COG0650	Formate hydrogenlyase subunit 4
TBCH5v1_1724	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TBCH5v1_1725	COG3260	NADH ubiquinone oxidoreductase 20
TBCH5v1_1727	COG0651	ATP synthesis coupled electron transport
TBCH5v1_1728	COG1006	Multisubunit Na H antiporter MnhC subunit
TBCH5v1_1732	COG1320	monovalent cation:proton antiporter activity
TBCH5v1_1733	COG2212	antiporter activity
TBCH5v1_1736	COG0650	Formate hydrogenlyase subunit 4
TBCH5v1_1738	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
TBCH5v1_1738	COG3261	NADH dehydrogenase
TBCH5v1_1739	COG3260	NADH ubiquinone oxidoreductase 20
TBCH5v1_1741	COG0651	ATP synthesis coupled electron transport
TBCH5v1_1746	COG1320	monovalent cation:proton antiporter activity
TBCH5v1_1747	COG2212	antiporter activity
TBCH5v1_1749	COG0651	ATP synthesis coupled electron transport
TBCH5v1_1751	COG1006	Multisubunit Na H antiporter MnhC subunit
TBCH5v1_1752	COG2111	Na H antiporter
TBCH5v1_1754	COG1320	monovalent cation:proton antiporter activity
TBCH5v1_1756	COG2116	formate transmembrane transporter activity
TBCH5v1_1758	COG3260	NADH ubiquinone oxidoreductase 20
TBCH5v1_1759	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TBCH5v1_1760	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
TBCH5v1_1760	COG3261	NADH dehydrogenase
TBCH5v1_1761	COG0650	Formate hydrogenlyase subunit 4
TBCH5v1_1762	COG0651	ATP synthesis coupled electron transport
TBCH5v1_1763	COG0651	ATP synthesis coupled electron transport
TBCH5v1_1764	COG0651	ATP synthesis coupled electron transport
TBCH5v1_1765	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TBCH5v1_1766	COG0437	4 iron, 4 sulfur cluster binding
TBCH5v1_1767	COG3383	formate dehydrogenase (NAD+) activity
TBCH5v1_1768	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
TBCH5v1_1769	COG3259	Nickel-dependent hydrogenase
TBCH5v1_1771	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TBCH5v1_1772	COG3259	Nickel-dependent hydrogenase
TBCH5v1_1773	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TBCH5v1_1774	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TBCH5v1_1777	COG1476	TRANSCRIPTIONal
TBCH5v1_1779	COG1131	(ABC) transporter
TBCH5v1_1786	COG4608	Belongs to the ABC transporter superfamily
TBCH5v1_1787	COG0444	Belongs to the ABC transporter superfamily
TBCH5v1_1789	COG0601	transmembrane transport
TBCH5v1_1790	COG0747	negative chemotaxis
TBCH5v1_1795	COG0543	2 iron, 2 sulfur cluster binding
TBCH5v1_1796	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
TBCH5v1_1796	COG0493	'glutamate synthase
TBCH5v1_1798	COG0509	glycine decarboxylation via glycine cleavage system
TBCH5v1_1801	COG1254	Belongs to the acylphosphatase family
TBCH5v1_1802	COG1324	tolerance protein
TBCH5v1_1803	COG1628	Protein of unknown function DUF99
TBCH5v1_1805	COG0167	dihydroorotate dehydrogenase activity
TBCH5v1_1806	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
TBCH5v1_1809	COG2255	four-way junction helicase activity
TBCH5v1_1811	COG0492	ferredoxin-NADP+ reductase activity
TBCH5v1_1812	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TBCH5v1_1815	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TBCH5v1_1818	COG0148	phosphopyruvate hydratase activity
TBCH5v1_1819	COG0463	Glycosyl transferase, family 2
TBCH5v1_1820	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TBCH5v1_1822	COG2234	aminopeptidase activity
TBCH5v1_1832	COG2264	protein methyltransferase activity
TBCH5v1_1836	COG0124	histidyl-tRNA synthetase
TBCH5v1_1841	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TBCH5v1_1842	COG1115	amino acid carrier protein
TBCH5v1_1844	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TBCH5v1_1846	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
TBCH5v1_1853	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TBCH5v1_1855	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TBCH5v1_1857	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TBCH5v1_1858	COG0569	domain protein
TBCH5v1_1860	COG1269	ATP hydrolysis coupled proton transport
TBCH5v1_1862	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
TBCH5v1_1865	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
TBCH5v1_1868	COG0426	domain, Protein
TBCH5v1_1868	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TBCH5v1_1869	COG0840	transmembrane signaling receptor activity
TBCH5v1_1870	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TBCH5v1_1871	COG0482	sulfurtransferase activity
TBCH5v1_1874	COG0543	2 iron, 2 sulfur cluster binding
TBCH5v1_1875	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TBCH5v1_1877	COG0601	transmembrane transport
TBCH5v1_1878	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TBCH5v1_1879	COG0444	Belongs to the ABC transporter superfamily
TBCH5v1_1880	COG4608	Belongs to the ABC transporter superfamily
TBCH5v1_1885	COG0174	glutamine synthetase
TBCH5v1_1895	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TBCH5v1_1896	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
TBCH5v1_1900	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
TBCH5v1_1905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TBCH5v1_1906	COG1234	tRNA 3'-trailer cleavage
TBCH5v1_1909	COG3842	ATPase activity
TBCH5v1_1911	COG3833	ABC-type maltose transport systems, permease component
TBCH5v1_1912	COG1175	transmembrane transport
TBCH5v1_1916	COG1378	Sugar-specific transcriptional regulator TrmB
TBCH5v1_1917	COG0297	glycogen (starch) synthase activity
TBCH5v1_1929	COG1335	isochorismatase
TBCH5v1_1932	COG2050	protein possibly involved in aromatic compounds catabolism
TBCH5v1_1932	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TBCH5v1_1933	COG1695	Transcriptional regulator
TBCH5v1_1948	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TBCH5v1_1948	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TBCH5v1_1949	COG2078	PFAM AMMECR1 domain protein
TBCH5v1_1960	COG0235	Class ii aldolase
TBCH5v1_1963	COG2252	PERMEase
TBCH5v1_1967	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
TBCH5v1_1971	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TBCH5v1_1972	COG0281	malic enzyme
TBCH5v1_1975	COG1175	transmembrane transport
TBCH5v1_1976	COG0395	ABC-type sugar transport system, permease component
TBCH5v1_1983	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TBCH5v1_1985	COG0577	efflux transmembrane transporter activity
TBCH5v1_1985	COG1136	(ABC) transporter
TBCH5v1_1987	COG1136	(ABC) transporter
TBCH5v1_1988	COG0589	response to stress
TBCH5v1_1997	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
TBCH5v1_1997	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
TBCH5v1_1999	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TBCH5v1_2001	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
TBCH5v1_2007	COG0475	glutathione-regulated potassium exporter activity
TBCH5v1_2010	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TBCH5v1_2011	COG0306	phosphate transporter
TBCH5v1_2013	COG1144	Oxidoreductase
TBCH5v1_2014	COG0674	pyruvate-flavodoxin oxidoreductase activity
TBCH5v1_2015	COG1013	pyruvate-flavodoxin oxidoreductase activity
TBCH5v1_2017	COG0674	pyruvate-flavodoxin oxidoreductase activity
TBCH5v1_2018	COG1013	pyruvate-flavodoxin oxidoreductase activity
TBCH5v1_2019	COG0489	protein tyrosine kinase activity
TBCH5v1_2024	COG1131	(ABC) transporter
TBCH5v1_2027	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TBCH5v1_2029	COG4143	(ABC) transporter
TBCH5v1_2033	COG1444	tRNA N-acetyltransferase activity
TBCH5v1_2034	COG4946	Tricorn protease homolog
TBCH5v1_2034	COG1506	peptidase
TBCH5v1_2034	COG0823	Involved in the tonB-independent uptake of proteins
TBCH5v1_2036	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
TBCH5v1_2038	COG1268	BioY protein
TBCH5v1_2039	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
TBCH5v1_2039	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
TBCH5v1_2041	COG1122	ATPase activity
TBCH5v1_2042	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
TBCH5v1_2046	COG4555	ABC transporter
TBCH5v1_2054	COG1111	helicase
TBCH5v1_2054	COG1205	dead DEAH box helicase
TBCH5v1_2055	COG1522	sequence-specific DNA binding
TBCH5v1_2056	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TBCH5v1_2060	COG0306	phosphate transporter
TBCH5v1_2065	COG4946	Tricorn protease homolog
TBCH5v1_2065	COG1506	peptidase
TBCH5v1_2065	COG0823	Involved in the tonB-independent uptake of proteins
TBCH5v1_2072	COG0681	Belongs to the peptidase S26 family
TBCH5v1_2073	COG0095	Lipoate-protein ligase
TBCH5v1_2081	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TBCH5v1_2090	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TBCH5v1_2092	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TBCH5v1_2105	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TBCH5v1_2107	COG0501	Belongs to the peptidase M48B family
TBCH5v1_2113	COG0314	molybdopterin synthase activity
TBCH5v1_2118	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TBCH5v1_2119	COG1522	sequence-specific DNA binding
TBCH5v1_2121	COG1980	fructose-bisphosphate aldolase activity
TBCH5v1_2123	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TBCH5v1_2124	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
TBCH5v1_2126	COG2376	Dihydroxyacetone kinase
TBCH5v1_2128	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
TBCH5v1_2136	COG3842	ATPase activity
TBCH5v1_2142	COG0463	Glycosyl transferase, family 2
TBCH5v1_2150	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
TBCH5v1_2154	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
TBCH5v1_2173	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
TBCH5v1_2176	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TBCH5v1_2179	COG0402	S-adenosylhomocysteine deaminase activity
TBCH5v1_2181	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
TBCH5v1_2181	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TBCH5v1_2183	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TBCH5v1_2183	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
TBCH5v1_2187	COG0640	Transcriptional regulator
TBCH5v1_2189	COG0180	Tryptophanyl-tRNA synthetase
TBCH5v1_2196	COG0179	Fumarylacetoacetate (FAA) hydrolase
TBCH5v1_2198	COG0704	Plays a role in the regulation of phosphate uptake
TBCH5v1_2199	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TBCH5v1_2206	COG0116	Belongs to the methyltransferase superfamily
TBCH5v1_2206	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
TBCH5v1_2209	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
TBCH5v1_2210	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
TBCH5v1_2217	COG1047	Peptidyl-prolyl cis-trans
TBCH5v1_2222	COG0714	Associated with various cellular activities
TBCH5v1_2225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TBCH5v1_2226	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
TBCH5v1_2239	COG0037	tRNA processing
TBCH5v1_2243	COG0673	inositol 2-dehydrogenase activity
TBCH5v1_2250	COG0438	transferase activity, transferring glycosyl groups
TBCH5v1_2254	COG0438	transferase activity, transferring glycosyl groups
TBCH5v1_2255	COG2244	polysaccharide biosynthetic process
TBCH5v1_2257	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TBCH5v1_2264	COG1449	Belongs to the glycosyl hydrolase 57 family
TBCH5v1_2265	COG0037	tRNA processing
TBCH5v1_2268	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
TBCH5v1_2273	COG0475	glutathione-regulated potassium exporter activity
TBCH5v1_2274	COG0475	glutathione-regulated potassium exporter activity
TBCH5v1_2275	COG1522	sequence-specific DNA binding
TBCH5v1_2276	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TBCH5v1_2279	COG2894	cell division
TBCH5v1_2280	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
TBCH5v1_2281	COG1793	dna ligase
TBCH5v1_2284	COG2189	Belongs to the N(4) N(6)-methyltransferase family
TBCH5v1_2286	COG1757	Na H antiporter
TBCH5v1_2287	COG1573	uracil-dna glycosylase
TBCH5v1_2289	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TBCH5v1_2291	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TBCH5v1_2295	COG0395	ABC-type sugar transport system, permease component
TBCH5v1_2296	COG0438	transferase activity, transferring glycosyl groups
TBCH5v1_2299	COG1380	Effector of murein hydrolase LrgA
TBCH5v1_2300	COG1346	cytolysis
TBCH5v1_2348	COG0668	transmembrane transport
TBCH5v1_2366	COG1518	maintenance of DNA repeat elements
TBCH5v1_2367	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TBCH5v1_2389	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
TBCH5v1_2393	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
TBCH5v1_2394	COG0218	Necessary for normal cell division and for the maintenance of normal septation
TBCH5v1_2410	COG1404	Belongs to the peptidase S8 family
TBCH5v1_2411	COG2890	protein-(glutamine-N5) methyltransferase activity
TBCH5v1_2423	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TBCH5v1_2423	COG0519	Catalyzes the synthesis of GMP from XMP
TBCH5v1_2426	COG0519	Catalyzes the synthesis of GMP from XMP
TBCH5v1_2426	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TBCH5v1_2428	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
TBCH5v1_2429	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
TBCH5v1_2430	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
TBCH5v1_2431	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
TBCH5v1_2432	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
TBCH5v1_2434	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
TBCH5v1_2435	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
TBCH5v1_2436	COG0151	Belongs to the GarS family
TBCH5v1_2438	COG1132	(ABC) transporter
TBCH5v1_2440	COG0047	phosphoribosylformylglycinamidine synthase activity
TBCH5v1_2441	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TBCH5v1_2442	COG0516	GMP reductase activity
TBCH5v1_2442	COG0517	IMP dehydrogenase activity
TBCH5v1_2447	COG1785	Belongs to the alkaline phosphatase family
TBCH5v1_2454	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TBCH5v1_2456	COG2046	Belongs to the sulfate adenylyltransferase family
TBCH5v1_2461	COG0730	response to heat
TBCH5v1_2492	COG1091	dTDP-4-dehydrorhamnose reductase activity
TBCH5v1_2497	COG1088	dTDP-glucose 4,6-dehydratase activity
TBCH5v1_2498	COG0438	transferase activity, transferring glycosyl groups
TBCH5v1_2502	COG0438	transferase activity, transferring glycosyl groups
TBCH5v1_2505	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
TBCH5v1_2507	COG1216	Glycosyl transferase, family 2
TBCH5v1_2510	COG0714	Associated with various cellular activities
TBCH5v1_2517	COG0647	UMP catabolic process
TBCH5v1_2521	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
TBCH5v1_2545	COG1543	Belongs to the glycosyl hydrolase 57 family
TBCH5v1_2546	COG0347	Belongs to the P(II) protein family
TBCH5v1_2548	COG0733	neurotransmitter:sodium symporter activity
TBCH5v1_2550	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TBCH5v1_2554	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
TBCH5v1_2555	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TBCH5v1_2558	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
TBCH5v1_2560	COG0022	dehydrogenase e1 component
TBCH5v1_2561	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
TBCH5v1_2562	COG0508	dehydrogenase complex catalyzes the overall conversion of
TBCH5v1_2563	COG0508	dehydrogenase complex catalyzes the overall conversion of
TBCH5v1_2565	COG3199	ATP-NAD kinase
TBCH5v1_2603	COG0534	Mate efflux family protein
TBCH5v1_2604	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TBCH5v1_2604	COG0574	Belongs to the PEP-utilizing enzyme family
TBCH5v1_2608	COG1473	amidohydrolase
TBCH5v1_2609	COG1404	Belongs to the peptidase S8 family
TBCH5v1_2610	COG0330	HflC and HflK could
TBCH5v1_2615	COG0446	pyridine nucleotide-disulphide oxidoreductase
TBCH5v1_2620	COG0731	radical SAM domain protein
TBCH5v1_2620	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TBCH5v1_2625	COG0409	Hydrogenase expression formation protein
TBCH5v1_2626	COG0298	carbon dioxide binding
TBCH5v1_2630	COG1120	ATPase activity
TBCH5v1_2633	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
TBCH5v1_2636	COG1063	alcohol dehydrogenase
TBCH5v1_2637	COG0746	molybdenum cofactor guanylyltransferase activity
TBCH5v1_2643	COG1234	tRNA 3'-trailer cleavage
TBCH5v1_2647	COG1994	Peptidase M50
TBCH5v1_2648	COG2140	Oxalate decarboxylase
TBCH5v1_2653	COG0601	transmembrane transport
TBCH5v1_2655	COG0444	Belongs to the ABC transporter superfamily
TBCH5v1_2656	COG4608	Belongs to the ABC transporter superfamily
TBCH5v1_2659	COG1482	cell wall glycoprotein biosynthetic process
TBCH5v1_2661	COG0383	alpha-mannosidase activity
TBCH5v1_2662	COG1522	sequence-specific DNA binding
TBCH5v1_2664	COG1063	alcohol dehydrogenase
TBCH5v1_2665	COG1402	creatininase
TBCH5v1_2666	COG1063	alcohol dehydrogenase
TBCH5v1_2667	COG2721	sulfolactate sulfo-lyase activity
TBCH5v1_2668	COG2721	sulfolactate sulfo-lyase activity
TBCH5v1_2669	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TBCH5v1_2670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TBCH5v1_2671	COG1063	alcohol dehydrogenase
TBCH5v1_2675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TBCH5v1_2679	COG1122	ATPase activity
TBCH5v1_2682	COG0310	cobalt ion transport
TBCH5v1_2686	COG3263	regulation of cellular component size
TBCH5v1_2687	COG0010	Belongs to the arginase family
TBCH5v1_2691	COG1748	Saccharopine dehydrogenase
TBCH5v1_2692	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
TBCH5v1_2696	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
TBCH5v1_2696	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TBCH5v1_2697	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TBCH5v1_2698	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
TBCH5v1_2701	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
TBCH5v1_2704	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TBCH5v1_2709	COG0017	Asparaginyl-tRNA synthetase
TBCH5v1_2711	COG0778	Nitroreductase
TBCH5v1_2712	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
TBCH5v1_2712	COG0493	'glutamate synthase
TBCH5v1_2713	COG0543	2 iron, 2 sulfur cluster binding
TBCH5v1_2715	COG0543	2 iron, 2 sulfur cluster binding
TBCH5v1_2717	COG3259	Nickel-dependent hydrogenase
TBCH5v1_2722	COG0430	RNA-3'-phosphate cyclase activity