locus-tag	class	description
A3L01_00010	ENOG4105CJ1	ABC, transporter
A3L01_00035	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A3L01_00040	ENOG4108IYU	L-aspartate oxidase
A3L01_00045	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
A3L01_00050	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A3L01_00055	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
A3L01_00060	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
A3L01_00065	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A3L01_00085	ENOG4105C8V	SAICAR synthetase
A3L01_00095	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
A3L01_00100	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
A3L01_00105	ENOG4107QNG	Phosphoribosylglycinamide synthetase
A3L01_00120	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
A3L01_00125	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
A3L01_00135	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A3L01_00140	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A3L01_00210	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A3L01_00250	ENOG4105F0N	pyrophosphate phospho-hydrolase
A3L01_00310	ENOG4105EHU	Circadian clock protein KaiC
A3L01_00320	ENOG4105IIU	Aminopeptidase
A3L01_00385	ENOG4105K8R	UPF0145 protein
A3L01_00405	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A3L01_00420	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3L01_00425	ENOG4105D64	Mechanosensitive ion channel
A3L01_00460	ENOG4105EM7	Selenocysteine-specific translation elongation factor
A3L01_00480	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
A3L01_00485	ENOG410825M	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A3L01_00490	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A3L01_00550	ENOG4105C7N	Xanthine uracil vitamin C permease
A3L01_00560	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A3L01_00565	ENOG4106SMU	thiamine transporter membrane protein
A3L01_00595	ENOG4105NBF	ammecr1 domain protein
A3L01_00605	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3L01_00610	ENOG4105CQ2	DNA polymerase
A3L01_00665	ENOG4105DP8	Major facilitator superfamily MFS_1
A3L01_00670	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L01_00695	ENOG4105HDK	L-asparaginase
A3L01_00705	ENOG4105VUN	Transcriptional regulator
A3L01_00710	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A3L01_00725	ENOG4108RWI	nicotinamidase
A3L01_00755	ENOG4105DQU	oxidoreductase, subunit beta
A3L01_00795	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L01_00800	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L01_00805	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
A3L01_00840	ENOG4105C2X	Arabinose 5-phosphate isomerase
A3L01_00845	ENOG4105D9Q	decarboxylase (Beta subunit)
A3L01_00850	ENOG4107QSA	Oxaloacetate decarboxylase
A3L01_00860	ENOG4105D8K	carboxyl transferase
A3L01_00895	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
A3L01_00920	ENOG4105DPX	Hydrogenase, large subunit
A3L01_00930	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
A3L01_00945	ENOG4107QIZ	NADH dehydrogenase
A3L01_00965	ENOG4105C9B	Cysteine desulfurase
A3L01_00985	ENOG4105C5R	Aminotransferase
A3L01_01030	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A3L01_01040	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A3L01_01045	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A3L01_01050	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A3L01_01060	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A3L01_01065	ENOG41082SA	50s ribosomal protein l29
A3L01_01070	ENOG4108ZJT	translation initiation factor, Sui1
A3L01_01080	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A3L01_01085	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
A3L01_01090	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
A3L01_01100	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A3L01_01110	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A3L01_01115	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
A3L01_01130	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
A3L01_01135	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A3L01_01140	ENOG410849U	50S ribosomal protein L30
A3L01_01145	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A3L01_01170	ENOG4108Z4J	Cytidine monophosphate kinase
A3L01_01180	ENOG4108IXY	short-chain dehydrogenase reductase
A3L01_01185	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A3L01_01200	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A3L01_01205	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A3L01_01210	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A3L01_01230	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A3L01_01235	ENOG4108UJD	30S ribosomal protein S9
A3L01_01260	ENOG4105CE9	30S ribosomal protein S2
A3L01_01300	ENOG4108YXU	transcriptional regulator AsnC family
A3L01_01310	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A3L01_01345	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
A3L01_01360	ENOG4108I5U	Uridine phosphorylase
A3L01_01365	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
A3L01_01370	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
A3L01_01375	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
A3L01_01390	ENOG4108IFG	nitrite reductase, (NAD(P)H)
A3L01_01400	ENOG4108XIB	electron transport protein ysaA
A3L01_01405	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
A3L01_01410	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
A3L01_01420	ENOG4105CN5	Metallo-Beta-Lactamase
A3L01_01425	ENOG4105EAH	synthase
A3L01_01430	ENOG4105C57	major facilitator superfamily
A3L01_01435	ENOG4105C8T	Leucyl-tRNA synthetase
A3L01_01445	ENOG4105EFZ	amidohydrolase
A3L01_01450	ENOG4105DC7	peptidase M24
A3L01_01485	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A3L01_01500	ENOG4105MRR	Transcriptional regulator (By similarity)
A3L01_01515	ENOG4107RFW	hydrolase family 57
A3L01_01520	ENOG4108YZA	Nitrogen regulatory protein pii
A3L01_01530	ENOG4105C8J	)-transporter
A3L01_01535	ENOG4105D82	Glutamate dehydrogenase
A3L01_01550	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
A3L01_01555	ENOG4105CY0	Metallo-Beta-Lactamase
A3L01_01570	ENOG4105E66	phosphoriboisomerase A
A3L01_01580	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A3L01_01585	ENOG4105UQX	Mate efflux family protein
A3L01_01590	ENOG4105UQX	Mate efflux family protein
A3L01_01595	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
A3L01_01610	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A3L01_01625	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
A3L01_01640	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L01_01660	ENOG4105C9B	Cysteine desulfurase
A3L01_01670	ENOG4105C45	hydrogenase expression formation protein (HypE)
A3L01_01680	ENOG4105CQS	hydrogenase expression formation protein HypD
A3L01_01690	ENOG41083NF	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A3L01_01745	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
A3L01_01750	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A3L01_01765	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A3L01_01780	ENOG4108Z4T	Peptidase M50
A3L01_01785	ENOG4108Y83	glucose-6-phosphate isomerase
A3L01_01805	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
A3L01_01835	ENOG4105G01	cobalamin (vitamin B12) biosynthesis CbiM protein
A3L01_01850	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L01_01895	ENOG4105CHM	Aminotransferase
A3L01_01920	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A3L01_01930	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A3L01_01950	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A3L01_01960	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A3L01_01995	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3L01_02055	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
A3L01_02070	ENOG4107TE1	transport protein
A3L01_02085	ENOG4105CJ1	ABC, transporter
A3L01_02095	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A3L01_02105	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
A3L01_02110	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
A3L01_02115	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
A3L01_02120	ENOG4105CX6	glutaminyL-tRNA synthetase
A3L01_02145	ENOG4105DHP	deoxycytidine triphosphate deaminase
A3L01_02170	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
A3L01_02175	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A3L01_02190	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A3L01_02225	ENOG4108T9Q	UPF0278 protein
A3L01_02240	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A3L01_02260	ENOG4108JU3	Alkyl hydroperoxide reductase
A3L01_02270	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
A3L01_02325	ENOG4105CD5	CoA-binding domain protein
A3L01_02345	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
A3L01_02370	ENOG4108VA3	3-hexulose-6-phosphate synthase
A3L01_02380	ENOG4107XGZ	Hydrolase
A3L01_02405	ENOG4105C5S	asparaginyl-tRNA synthetase
A3L01_02420	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
A3L01_02435	ENOG4105CH2	amidohydrolase
A3L01_02465	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A3L01_02485	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L01_02500	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
A3L01_02510	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A3L01_02520	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A3L01_02525	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
A3L01_02530	ENOG4108JJB	ABC transporter
A3L01_02550	ENOG4105CN9	Peptidase m42 family protein
A3L01_02565	ENOG4108Z0R	Transferase
A3L01_02570	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A3L01_02580	ENOG4105C22	threonyL-tRNA synthetase
A3L01_02625	ENOG4105F4G	Membrane
A3L01_02630	ENOG4105EEI	dihydropteroate synthase
A3L01_02655	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
A3L01_02660	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A3L01_02665	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A3L01_02670	ENOG4107TIA	phenylalanyl-tRNA synthetase (beta subunit)
A3L01_02675	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A3L01_02680	ENOG4105CPQ	Dehydrogenase
A3L01_02685	ENOG4107U53	septum site-determining protein minD
A3L01_02705	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A3L01_02710	ENOG4105HDK	L-asparaginase
A3L01_02740	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A3L01_02780	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
A3L01_02790	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
A3L01_02795	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
A3L01_02805	ENOG4105CMQ	Chloride channel
A3L01_02870	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3L01_02880	ENOG4105DBV	ornithine carbamoyltransferase
A3L01_02895	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
A3L01_02910	ENOG4105E3H	phosphoglycerate mutase
A3L01_02955	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A3L01_02970	ENOG4105BZR	domain protein
A3L01_03020	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A3L01_03030	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A3L01_03065	ENOG4105CHR	reductase
A3L01_03070	ENOG4108V1U	phospholipid-binding protein
A3L01_03125	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
A3L01_03130	ENOG4108JPW	Aminotransferase
A3L01_03155	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L01_03160	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A3L01_03165	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L01_03175	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L01_03180	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L01_03185	ENOG4105MKQ	Monovalent cation H antiporter subunit C
A3L01_03190	ENOG4105D65	subunit l
A3L01_03200	ENOG4105KJM	monovalent cation h antiporter subunit g
A3L01_03205	ENOG410684G	monovalent cation H antiporter subunit F
A3L01_03210	ENOG4105SC1	monovalent cation H antiporter subunit E
A3L01_03220	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A3L01_03230	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
A3L01_03235	ENOG4108IJ1	Dehydrogenase
A3L01_03255	ENOG4105C75	arginyL-tRNA synthetase
A3L01_03260	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A3L01_03330	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
A3L01_03350	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A3L01_03360	ENOG4108VVK	transcriptional Regulator, AsnC
A3L01_03380	ENOG4105KME	endoribonuclease L-psp
A3L01_03390	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A3L01_03395	ENOG4105C3K	feS assembly ATPase SufC
A3L01_03440	ENOG4105CJ1	ABC, transporter
A3L01_03450	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
A3L01_03490	ENOG4105C1A	potassium transporter peripheral membrane
A3L01_03510	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
A3L01_03520	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
A3L01_03530	ENOG4105CAT	Cytidine monophosphate kinase
A3L01_03535	ENOG4105D0M	Protease HtpX homolog
A3L01_03540	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A3L01_03545	ENOG4105CHM	Aminotransferase
A3L01_03560	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A3L01_03565	ENOG4105C5I	Dehydrogenase
A3L01_03570	ENOG4105CN9	Peptidase m42 family protein
A3L01_03615	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
A3L01_03640	ENOG4105DQU	oxidoreductase, subunit beta
A3L01_03645	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
A3L01_03655	ENOG4105DQU	oxidoreductase, subunit beta
A3L01_03660	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
A3L01_03675	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
A3L01_03685	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A3L01_03695	ENOG4105DIH	basic membrane
A3L01_03700	ENOG4108JQ9	ABC transporter
A3L01_03705	ENOG4105UIB	(ABC) transporter
A3L01_03730	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
A3L01_03735	ENOG4105C8N	cysteinyl-tRNA synthetase
A3L01_03740	ENOG4108YZY	peptidylprolyl cis-trans isomerase
A3L01_03765	ENOG4105EHU	Circadian clock protein KaiC
A3L01_03770	ENOG4107QRT	dEAD DEAH box helicase
A3L01_03780	ENOG4107QJZ	Glycosyl transferase, family 2
A3L01_03790	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
A3L01_03810	ENOG4107XGZ	Hydrolase
A3L01_03855	ENOG4105DER	m42 family
A3L01_03915	ENOG4108WBT	adenosyltransferase
A3L01_03925	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A3L01_03930	ENOG4105CEV	competence damage-inducible protein
A3L01_03940	ENOG4105VZ9	UPF0235 protein
A3L01_03955	ENOG4105VXP	Protein of unknown function DUF86
A3L01_03960	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
A3L01_03975	ENOG4105UQX	Mate efflux family protein
A3L01_03995	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
A3L01_04010	ENOG4105DC7	peptidase M24
A3L01_04025	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A3L01_04040	ENOG4105CE1	Ferrous iron transport protein b
A3L01_04060	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
A3L01_04075	ENOG4105C3G	gtp-binding protein
A3L01_04090	ENOG4105D7N	magnesium and cobalt transport protein CorA
A3L01_04095	ENOG4105CG9	aspartate racemase
A3L01_04155	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A3L01_04160	ENOG4105DXX	methyltransferase
A3L01_04165	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A3L01_04170	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
A3L01_04175	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
A3L01_04185	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
A3L01_04190	ENOG4105GSQ	TM1410 hypothetical-related protein
A3L01_04195	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A3L01_04205	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
A3L01_04210	ENOG4108K7V	UPF0284 protein
A3L01_04220	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
A3L01_04225	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A3L01_04250	ENOG4105DCI	Phosphohydrolase
A3L01_04260	ENOG4105KNA	-acetyltransferase
A3L01_04270	ENOG4105E0R	Deoxyhypusine synthase
A3L01_04275	ENOG4105CHR	reductase
A3L01_04280	ENOG4105D3W	isochorismatase
A3L01_04285	ENOG4105CAY	ferredoxin--nadp reductase
A3L01_04290	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
A3L01_04300	ENOG4105D0M	Protease HtpX homolog
A3L01_04305	ENOG4105D0M	Protease HtpX homolog
A3L01_04320	ENOG4105G0J	serine threonine protein kinase
A3L01_04325	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
A3L01_04335	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A3L01_04365	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3L01_04375	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
A3L01_04380	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
A3L01_04410	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
A3L01_04420	ENOG4108I5C	dEAD DEAH box helicase
A3L01_04430	ENOG4105FDK	ABC transporter
A3L01_04505	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L01_04510	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
A3L01_04555	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
A3L01_04560	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A3L01_04570	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A3L01_04585	ENOG4105DCI	Phosphohydrolase
A3L01_04590	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
A3L01_04615	ENOG41065SU	Two-component system sensor kinase
A3L01_04635	ENOG4105FDK	ABC transporter
A3L01_04645	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A3L01_04665	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A3L01_04680	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A3L01_04700	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
A3L01_04715	ENOG4107QTZ	amino acid
A3L01_04730	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A3L01_04770	ENOG4105WMR	Protein CrcB homolog
A3L01_04775	ENOG4105KJJ	Uncharacterized ACR, COG1993
A3L01_04780	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A3L01_04785	ENOG4105D64	Mechanosensitive ion channel
A3L01_04820	ENOG4107RDB	Major Facilitator
A3L01_04825	ENOG41079KZ	Major Facilitator Superfamily
A3L01_04855	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A3L01_04890	ENOG4108J2R	molybdopterin oxidoreductase
A3L01_04895	ENOG4105D3R	alkyl hydroperoxide reductase
A3L01_04925	ENOG4108MK9	spermidine N(1)-acetyltransferase
A3L01_04940	ENOG4105F4P	)-transporter
A3L01_04975	ENOG4108RAC	Rubrerythrin
A3L01_04980	ENOG4105VCQ	rubredoxin
A3L01_04985	ENOG4108YZ8	Superoxide reductase
A3L01_05030	ENOG4105N80	Ferric uptake regulator, Fur family
A3L01_05045	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
A3L01_05055	ENOG4105CIG	ABC transporter
A3L01_05085	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
A3L01_05095	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
A3L01_05100	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
A3L01_05105	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
A3L01_05110	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
A3L01_05115	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
A3L01_05120	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A3L01_05140	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A3L01_05150	ENOG4105CK2	sodium dicarboxylate symporter
A3L01_05155	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A3L01_05160	ENOG41061GT	Aldolase
A3L01_05165	ENOG4107QSA	Oxaloacetate decarboxylase
A3L01_05170	ENOG4105D22	carbon starvation protein
A3L01_05180	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
A3L01_05205	ENOG4105E5G	Alpha beta hydrolase fold
A3L01_05215	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A3L01_05235	ENOG4107QMS	site-determining protein
A3L01_05265	ENOG4108R96	Methyltransferase, YaeB family
A3L01_05270	ENOG4105CK7	Sodium proline symporter
A3L01_05320	ENOG4105VYW	UPF0251 protein
A3L01_05325	ENOG4105C83	adenylosuccinate lyase
A3L01_05350	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A3L01_05360	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A3L01_05365	ENOG4107QRT	dEAD DEAH box helicase
A3L01_05370	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A3L01_05385	ENOG4105C5X	domain protein
A3L01_05400	ENOG4105F8V	Hydrolase, tatD family
A3L01_05430	ENOG4105C5I	Dehydrogenase
A3L01_05435	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L01_05445	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
A3L01_05455	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
A3L01_05505	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A3L01_05565	ENOG4105C5S	asparaginyl-tRNA synthetase
A3L01_05605	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
A3L01_05610	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
A3L01_05630	ENOG4108MYP	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
A3L01_05645	ENOG4105VKD	bioY protein
A3L01_05650	ENOG4108JJB	ABC transporter
A3L01_05655	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
A3L01_05700	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
A3L01_05705	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A3L01_05770	ENOG4105CSM	endonuclease III
A3L01_05805	ENOG4105CD5	CoA-binding domain protein
A3L01_05810	ENOG4107RGD	Major Facilitator superfamily
A3L01_05835	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A3L01_05855	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A3L01_05880	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A3L01_05890	ENOG4107R8N	Glycosyl transferase, family 2
A3L01_05895	ENOG4105PW4	Sugar fermentation stimulation protein homolog
A3L01_05905	ENOG4105CN9	Peptidase m42 family protein
A3L01_05915	ENOG4105DVT	helicase
A3L01_05950	ENOG4108MWI	inositol mono-phosphatase
A3L01_05960	ENOG4105C0A	alcohol dehydrogenase
A3L01_05975	ENOG4105P4J	Allophanate hydrolase, subunit 1
A3L01_05980	ENOG4105E7W	lamb ycsf family protein
A3L01_06020	ENOG4107QX8	SPFH domain, Band 7 family protein
A3L01_06025	ENOG4107QMS	site-determining protein
A3L01_06040	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
A3L01_06055	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
A3L01_06070	ENOG4105C1J	atp-dependent rna helicase
A3L01_06095	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
A3L01_06115	ENOG4105D5P	Methylmalonyl-coA mutase
A3L01_06125	ENOG4108Z03	MAF-like protein
A3L01_06170	ENOG4105CAQ	asparagine synthetase
A3L01_06185	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A3L01_06205	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
A3L01_06210	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A3L01_06220	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A3L01_06235	ENOG4105CD5	CoA-binding domain protein
A3L01_06280	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A3L01_06325	ENOG4107T0X	DNA ligase
A3L01_06330	ENOG4107Y70	Heat shock protein
A3L01_06370	ENOG4105C8J	)-transporter
A3L01_06380	ENOG4105DEF	Extracellular solute-binding protein, family 5
A3L01_06385	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A3L01_06390	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A3L01_06400	ENOG4108JQ7	(ABC) transporter
A3L01_06410	ENOG4107SA6	carbon-phosphorus lyase complex accessory protein
A3L01_06420	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
A3L01_06530	ENOG4105EAC	phosphoserine phosphatase
A3L01_06535	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
A3L01_06560	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
A3L01_06565	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
A3L01_06570	ENOG4108R96	Methyltransferase, YaeB family
A3L01_06575	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A3L01_06580	ENOG4108I5D	sulfate abc transporter
A3L01_06585	ENOG41066FR	extracellular solute-binding protein
A3L01_06605	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A3L01_06610	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
A3L01_06640	ENOG4105K4P	CoA-binding domain protein
A3L01_06670	ENOG4105D1Z	hydroxypyruvate reductase
A3L01_06680	ENOG4108IJ9	(ABC) transporter
A3L01_06710	ENOG4106J7S	Glycosyl transferase, family 2
A3L01_06715	ENOG4105D7K	pfkb domain protein
A3L01_06725	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
A3L01_06740	ENOG41088YS	Glycosyl transferase (Group 1
A3L01_06785	ENOG4107104	thymidine kinase
A3L01_06790	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
A3L01_06835	ENOG4105CJ1	ABC, transporter
A3L01_06850	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
A3L01_06855	ENOG4108IJ9	(ABC) transporter
A3L01_06885	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
A3L01_06895	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
A3L01_06905	ENOG4107QJE	Chromosome Partitioning Protein
A3L01_06910	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A3L01_06915	ENOG4105MRR	Transcriptional regulator (By similarity)
A3L01_06925	ENOG4105CHM	Aminotransferase
A3L01_06965	ENOG4105VZ8	Transcriptional regulator
A3L01_06975	ENOG4105CJ1	ABC, transporter
A3L01_07010	ENOG4108JQ7	(ABC) transporter
A3L01_07020	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A3L01_07025	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A3L01_07030	ENOG4105DEF	Extracellular solute-binding protein, family 5
A3L01_07055	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
A3L01_07060	ENOG4105BZ8	glutamate synthase
A3L01_07075	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
A3L01_07080	ENOG4105SC1	monovalent cation H antiporter subunit E
A3L01_07085	ENOG41080TA	Multiple resistance and ph regulation protein f
A3L01_07090	ENOG4105KJM	monovalent cation h antiporter subunit g
A3L01_07115	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L01_07140	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
A3L01_07170	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
A3L01_07240	ENOG4105CHU	acetyl-coa acetyltransferase
A3L01_07245	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A3L01_07270	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A3L01_07275	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A3L01_07280	ENOG4108Z86	Glutamine amidotransferase
A3L01_07290	ENOG4108UKZ	OsmC family
A3L01_07295	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
A3L01_07315	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
A3L01_07330	ENOG4107R7Y	intracellular protease Pfpi family
A3L01_07340	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L01_07365	ENOG4105CK7	Sodium proline symporter
A3L01_07380	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
A3L01_07390	ENOG4105C2C	drug resistance transporter, Bcr CflA
A3L01_07405	ENOG4105CS2	ec 3.2.1.21
A3L01_07425	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
A3L01_07430	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
A3L01_07445	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
A3L01_07450	ENOG41080HI	glycine oxidase
A3L01_07485	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
A3L01_07490	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A3L01_07505	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
A3L01_07510	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
A3L01_07515	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A3L01_07525	ENOG4108JVH	Protein of unknown function DUF43
A3L01_07535	ENOG4105VG1	fes assembly suf system protein
A3L01_07545	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
A3L01_07555	ENOG4105CHR	reductase
A3L01_07575	ENOG4105BZ8	glutamate synthase
A3L01_07580	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
A3L01_07615	ENOG4105D0M	Protease HtpX homolog
A3L01_07620	ENOG4108UK2	deaminase
A3L01_07630	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A3L01_07635	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
A3L01_07645	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A3L01_07650	ENOG4105DJB	Major Facilitator Superfamily
A3L01_07675	ENOG4105D44	asparaginase
A3L01_07685	ENOG4107QNK	)-transporter
A3L01_07695	ENOG4105DK7	lysyl-tRNA synthetase
A3L01_07745	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A3L01_07780	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A3L01_07800	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A3L01_07805	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A3L01_07810	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A3L01_07840	ENOG4107WZZ	SMC domain protein
A3L01_07840	ENOG4107WZZ	SMC domain protein
A3L01_07860	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A3L01_07875	ENOG4105C7B	Threonine dehydratase
A3L01_07880	ENOG4105NBF	ammecr1 domain protein
A3L01_07885	ENOG4105E4P	ATPase (AAA
A3L01_07910	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
A3L01_07925	ENOG4105CXT	aspartate transcarbamylase
A3L01_07930	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
A3L01_07965	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
A3L01_07970	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A3L01_08010	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A3L01_08040	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
A3L01_08045	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
A3L01_08050	ENOG41067TZ	transcriptional regulator, MarR family
A3L01_08065	ENOG4108J9M	Transporter
A3L01_08095	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
A3L01_08100	ENOG4107GFK	fumarate
A3L01_08105	ENOG4106DSS	Tartrate dehydratase subunit alpha
A3L01_08110	ENOG4105E4P	ATPase (AAA
A3L01_08115	ENOG4108JQ1	Dehydrogenase
A3L01_08125	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
A3L01_08170	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A3L01_08175	ENOG4105CJ3	phosphate transporter
A3L01_08190	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
A3L01_08195	ENOG4105DDK	oxidoreductase, beta subunit
A3L01_08205	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
A3L01_08210	ENOG4105DDK	oxidoreductase, beta subunit
A3L01_08220	ENOG4105QAX	Iron-sulfur
A3L01_08225	ENOG4105BZ8	glutamate synthase
A3L01_08230	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
A3L01_08235	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
A3L01_08240	ENOG4105QAX	Iron-sulfur
A3L01_08245	ENOG41080XS	Cobyrinic acid ac-diamide synthase
A3L01_08250	ENOG4105D1F	ATP-binding protein
A3L01_08285	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
A3L01_08290	ENOG4105VF7	tolerance protein
A3L01_08295	ENOG4108UUC	Protein of unknown function DUF99
A3L01_08305	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A3L01_08325	ENOG4107NFR	Fructose-1,6-bisphosphatase
A3L01_08330	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
A3L01_08345	ENOG4107QN2	dihydrolipoyl dehydrogenase
A3L01_08360	ENOG4105EWK	phytoene
A3L01_08400	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A3L01_08410	ENOG4108VVK	transcriptional Regulator, AsnC
A3L01_08415	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L01_08425	ENOG4107U53	septum site-determining protein minD
A3L01_08450	ENOG4107S6Z	Na H antiporter
A3L01_08455	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
A3L01_08480	ENOG4105VAW	lrga family
A3L01_08485	ENOG41067MG	lrgb family
A3L01_08505	ENOG4108S8N	class II Aldolase
A3L01_08515	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
A3L01_08555	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
A3L01_08580	ENOG4108E19	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
A3L01_08605	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
A3L01_08630	ENOG4105CJ3	phosphate transporter
A3L01_08660	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A3L01_08665	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L01_08670	ENOG4105SC1	monovalent cation H antiporter subunit E
A3L01_08675	ENOG41080TA	Multiple resistance and ph regulation protein f
A3L01_08680	ENOG4105KJM	monovalent cation h antiporter subunit g
A3L01_08705	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L01_08715	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
A3L01_08720	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A3L01_08725	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
A3L01_08730	ENOG4107TDF	Formate hydrogenlyase subunit 4
A3L01_08735	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L01_08745	ENOG41080TA	Multiple resistance and ph regulation protein f
A3L01_08750	ENOG4105KJM	monovalent cation h antiporter subunit g
A3L01_08765	ENOG4108PMQ	Na H antiporter MnhB subunit-related protein
A3L01_08770	ENOG4105MKQ	Monovalent cation H antiporter subunit C
A3L01_08775	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L01_08785	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
A3L01_08790	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A3L01_08795	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
A3L01_08800	ENOG4107TDF	Formate hydrogenlyase subunit 4
A3L01_08805	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L01_08845	ENOG4105C3M	thioredoxin reductase
A3L01_08850	ENOG4108JPW	Aminotransferase
A3L01_08880	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A3L01_08895	ENOG4108VVK	transcriptional Regulator, AsnC
A3L01_08900	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A3L01_08920	ENOG4108ZAF	Molybdopterin
A3L01_08930	ENOG4105D06	uba thif-type nad fad binding protein
A3L01_08970	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3L01_08985	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A3L01_08995	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A3L01_09110	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
A3L01_09120	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A3L01_09130	ENOG4105D1H	recombination factor protein RarA
A3L01_09145	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
A3L01_09160	ENOG4105E5K	Alpha-amylase
A3L01_09165	ENOG41066UM	arsR family transcriptional regulator
A3L01_09175	ENOG41082SX	arsR family transcriptional regulator
A3L01_09200	ENOG4105ERH	Fumarylacetoacetate hydrolase
A3L01_09225	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
A3L01_09230	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A3L01_09265	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
A3L01_09285	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A3L01_09305	ENOG4105CTD	carboxy-peptidase
A3L01_09320	ENOG4107SCK	Monooxygenase
A3L01_09325	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
A3L01_09360	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
A3L01_09370	ENOG4105C0H	protease
A3L01_09380	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
A3L01_09385	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
A3L01_09395	ENOG4107QQG	Dehydrogenase
A3L01_09400	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A3L01_09415	ENOG4107TSN	permease
A3L01_09420	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
A3L01_09435	ENOG4107RIQ	Sulfate adenylate transferase
A3L01_09460	ENOG4105CS2	ec 3.2.1.21
A3L01_09465	ENOG4108J59	Extracellular solute-binding protein, family 5
A3L01_09470	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A3L01_09480	ENOG4105C3U	ABC transporter
A3L01_09485	ENOG4108JQ7	(ABC) transporter
A3L01_09490	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A3L01_09500	ENOG41076HS	cation diffusion facilitator family transporter
A3L01_09540	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
A3L01_09550	ENOG4107R56	PP-loop domain protein
A3L01_09565	ENOG4105CAY	ferredoxin--nadp reductase
A3L01_09570	ENOG4105CJW	magnesium transporter
A3L01_09575	ENOG4107RWR	Sodium hydrogen exchanger
A3L01_09580	ENOG4107RWR	Sodium hydrogen exchanger
A3L01_09590	ENOG4105CUT	histidyl-tRNA synthetase
A3L01_09670	ENOG4108JPW	Aminotransferase
A3L01_09675	ENOG4105BZG	amino acid carrier protein
A3L01_09720	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A3L01_09730	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
A3L01_09785	ENOG4105EHU	Circadian clock protein KaiC
A3L01_09795	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
A3L01_09800	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A3L01_09810	ENOG4105C1A	potassium transporter peripheral membrane
A3L01_09830	ENOG4105K4G	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A3L01_09840	ENOG4105KXQ	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A3L01_09845	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
A3L01_09855	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A3L01_09860	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A3L01_09905	ENOG4105CD3	dihydroorotase
A3L01_09920	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A3L01_09925	ENOG4105C3U	ABC transporter
A3L01_09930	ENOG4108JQ7	(ABC) transporter
A3L01_09940	ENOG4105C4K	Nad synthetase
A3L01_09950	ENOG4105C5F	glutamine synthetase
A3L01_09990	ENOG4105EHU	Circadian clock protein KaiC
A3L01_10010	ENOG4105DR4	Methyltransferase
A3L01_10025	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A3L01_10035	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A3L01_10040	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A3L01_10050	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A3L01_10070	ENOG4105EG2	ABC transporter, permease
A3L01_10080	ENOG4107FKK	extracellular solute-binding protein family 1
A3L01_10090	ENOG4108NGU	Transcriptional regulator
A3L01_10095	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
A3L01_10110	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A3L01_10145	ENOG4105E4P	ATPase (AAA
A3L01_10150	ENOG4105M7V	2'-5' rna ligase
A3L01_10155	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
A3L01_10160	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A3L01_10170	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
A3L01_10205	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A3L01_10220	ENOG4105CKK	Glycosyl transferase, family 2
A3L01_10245	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
A3L01_10255	ENOG4105CBG	Sulfatase
A3L01_10265	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
A3L01_10270	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
A3L01_10280	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase