A3L01_02195 6ab1317167f0cf2c2a415cbda3df42f3 272 Gene3D G3DSA:3.40.50.10700 187 272 3.0E-30 T 23-10-2018 A3L01_02195 6ab1317167f0cf2c2a415cbda3df42f3 272 Hamap MF_00562 D-aminoacyl-tRNA deacylase [dtdA]. 1 271 34.651 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 A3L01_02195 6ab1317167f0cf2c2a415cbda3df42f3 272 Gene3D G3DSA:3.40.630.50 1 186 2.2E-69 T 23-10-2018 A3L01_02195 6ab1317167f0cf2c2a415cbda3df42f3 272 PIRSF PIRSF016210 1 272 1.3E-82 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 A3L01_02195 6ab1317167f0cf2c2a415cbda3df42f3 272 SUPERFAMILY SSF142535 1 270 4.45E-86 T 23-10-2018 A3L01_02195 6ab1317167f0cf2c2a415cbda3df42f3 272 Pfam PF04414 D-aminoacyl-tRNA deacylase 69 269 1.1E-65 T 23-10-2018 IPR007508 D-aminoacyl-tRNA deacylase DtdA GO:0016788|GO:0051499 A3L01_00950 d3326e309418c2dd0e0418113a717300 952 PRINTS PR00419 Adrenodoxin reductase family signature 354 367 3.1E-22 T 23-10-2018 A3L01_00950 d3326e309418c2dd0e0418113a717300 952 PRINTS PR00419 Adrenodoxin reductase family signature 213 226 3.1E-22 T 23-10-2018 A3L01_00950 d3326e309418c2dd0e0418113a717300 952 PRINTS PR00419 Adrenodoxin reductase family signature 255 265 3.1E-22 T 23-10-2018 A3L01_00950 d3326e309418c2dd0e0418113a717300 952 PRINTS PR00419 Adrenodoxin reductase family signature 190 212 3.1E-22 T 23-10-2018 A3L01_00950 d3326e309418c2dd0e0418113a717300 952 PRINTS PR00419 Adrenodoxin reductase family signature 321 335 3.1E-22 T 23-10-2018 A3L01_00950 d3326e309418c2dd0e0418113a717300 952 Gene3D G3DSA:3.30.70.20 612 694 9.6E-14 T 23-10-2018 A3L01_00950 d3326e309418c2dd0e0418113a717300 952 SUPERFAMILY SSF46548 96 199 2.98E-21 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L01_00950 d3326e309418c2dd0e0418113a717300 952 SUPERFAMILY SSF54862 580 694 2.09E-19 T 23-10-2018 A3L01_00950 d3326e309418c2dd0e0418113a717300 952 SUPERFAMILY SSF51971 187 429 2.18E-75 T 23-10-2018 A3L01_00950 d3326e309418c2dd0e0418113a717300 952 Gene3D G3DSA:3.50.50.60 186 314 9.8E-38 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_00950 d3326e309418c2dd0e0418113a717300 952 Gene3D G3DSA:3.50.50.60 316 515 1.5E-31 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_00950 d3326e309418c2dd0e0418113a717300 952 Gene3D G3DSA:3.10.20.740 1 115 9.4E-26 T 23-10-2018 A3L01_00950 d3326e309418c2dd0e0418113a717300 952 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 98 176 1.9E-18 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A3L01_00950 d3326e309418c2dd0e0418113a717300 952 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 189 482 1.7E-43 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L01_00950 d3326e309418c2dd0e0418113a717300 952 SUPERFAMILY SSF53706 703 833 1.01E-15 T 23-10-2018 A3L01_00950 d3326e309418c2dd0e0418113a717300 952 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 73 1.3E-10 T 23-10-2018 A3L01_00950 d3326e309418c2dd0e0418113a717300 952 SUPERFAMILY SSF54292 1 97 1.8E-25 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A3L01_00950 d3326e309418c2dd0e0418113a717300 952 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 23-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_04260 e5ab07a75afb2904935a5dca907b809e 176 SUPERFAMILY SSF55729 2 173 4.15E-44 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L01_04260 e5ab07a75afb2904935a5dca907b809e 176 Gene3D G3DSA:3.40.630.30 4 173 3.1E-46 T 23-10-2018 A3L01_04260 e5ab07a75afb2904935a5dca907b809e 176 Pfam PF13302 Acetyltransferase (GNAT) domain 17 149 4.1E-29 T 23-10-2018 IPR000182 GNAT domain A3L01_05670 570bebcbf10a9dcec8d2b7bc254be669 268 Pfam PF01889 Membrane protein of unknown function DUF63 10 266 1.0E-71 T 23-10-2018 IPR002749 Protein of unknown function DUF63 A3L01_01085 80526e485c03baaa57b05262b3e6676e 141 SMART SM01374 20 141 1.6E-55 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A3L01_01085 80526e485c03baaa57b05262b3e6676e 141 TIGRFAM TIGR03673 uL14_arch: 50S ribosomal protein uL14 15 140 3.4E-60 T 23-10-2018 IPR019971 Ribosomal protein L14P, archaeal A3L01_01085 80526e485c03baaa57b05262b3e6676e 141 Gene3D G3DSA:2.40.150.20 1 140 3.4E-48 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 A3L01_01085 80526e485c03baaa57b05262b3e6676e 141 SUPERFAMILY SSF50193 16 141 1.44E-43 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 A3L01_01085 80526e485c03baaa57b05262b3e6676e 141 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 20 141 19.467 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A3L01_01085 80526e485c03baaa57b05262b3e6676e 141 Pfam PF00238 Ribosomal protein L14p/L23e 24 140 1.8E-34 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A3L01_10280 a930d411338852b80cf2ba1ffc467e28 352 TIGRFAM TIGR01208 rmlA_long: glucose-1-phosphate thymidylyltransferase 2 352 3.1E-165 T 23-10-2018 IPR005908 Glucose-1-phosphate thymidylyltransferase, long form A3L01_10280 a930d411338852b80cf2ba1ffc467e28 352 SUPERFAMILY SSF53448 1 304 3.99E-77 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_10280 a930d411338852b80cf2ba1ffc467e28 352 Pfam PF00483 Nucleotidyl transferase 3 234 3.6E-51 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L01_10280 a930d411338852b80cf2ba1ffc467e28 352 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 272 298 1.2E-5 T 23-10-2018 IPR001451 Hexapeptide repeat A3L01_10280 a930d411338852b80cf2ba1ffc467e28 352 Gene3D G3DSA:2.160.10.10 241 351 1.2E-12 T 23-10-2018 A3L01_10280 a930d411338852b80cf2ba1ffc467e28 352 Gene3D G3DSA:3.90.550.10 1 240 5.8E-69 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_03075 dfbac24ce62cfe8c81d2812e3ef10909 85 Gene3D G3DSA:1.20.1280.290 1 84 1.8E-10 T 23-10-2018 A3L01_03075 dfbac24ce62cfe8c81d2812e3ef10909 85 Pfam PF04193 PQ loop repeat 4 58 1.4E-4 T 23-10-2018 IPR006603 PQ-loop repeat A3L01_06205 c6e49ab00ff5c6e51fba25ea2d25057f 455 PRINTS PR00981 Seryl-tRNA synthetase signature 285 297 1.3E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L01_06205 c6e49ab00ff5c6e51fba25ea2d25057f 455 PRINTS PR00981 Seryl-tRNA synthetase signature 354 370 1.3E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L01_06205 c6e49ab00ff5c6e51fba25ea2d25057f 455 PRINTS PR00981 Seryl-tRNA synthetase signature 297 310 1.3E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L01_06205 c6e49ab00ff5c6e51fba25ea2d25057f 455 PRINTS PR00981 Seryl-tRNA synthetase signature 337 350 1.3E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L01_06205 c6e49ab00ff5c6e51fba25ea2d25057f 455 PRINTS PR00981 Seryl-tRNA synthetase signature 372 388 1.3E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L01_06205 c6e49ab00ff5c6e51fba25ea2d25057f 455 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 243 420 1.2E-38 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_06205 c6e49ab00ff5c6e51fba25ea2d25057f 455 Gene3D G3DSA:1.10.287.40 1 107 3.2E-34 T 23-10-2018 A3L01_06205 c6e49ab00ff5c6e51fba25ea2d25057f 455 SUPERFAMILY SSF46589 1 115 2.25E-27 T 23-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 A3L01_06205 c6e49ab00ff5c6e51fba25ea2d25057f 455 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 443 41.616 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L01_06205 c6e49ab00ff5c6e51fba25ea2d25057f 455 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 437 1.3E-161 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L01_06205 c6e49ab00ff5c6e51fba25ea2d25057f 455 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 109 1.8E-27 T 23-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 A3L01_06205 c6e49ab00ff5c6e51fba25ea2d25057f 455 Gene3D G3DSA:3.30.930.10 108 455 3.6E-134 T 23-10-2018 A3L01_06205 c6e49ab00ff5c6e51fba25ea2d25057f 455 SUPERFAMILY SSF55681 154 446 3.67E-87 T 23-10-2018 A3L01_06205 c6e49ab00ff5c6e51fba25ea2d25057f 455 PIRSF PIRSF001529 1 447 2.0E-153 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L01_08095 99c9a5bd30e5c51f364ab5a9d11ceb7b 538 PIRSF PIRSF000858 1 538 1.0E-184 T 23-10-2018 IPR014388 3-oxoacid CoA-transferase GO:0008410|GO:0046952 Reactome: R-HSA-77108 A3L01_08095 99c9a5bd30e5c51f364ab5a9d11ceb7b 538 SUPERFAMILY SSF100950 4 269 5.13E-65 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L01_08095 99c9a5bd30e5c51f364ab5a9d11ceb7b 538 SMART SM00882 5 253 8.0E-39 T 23-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A3L01_08095 99c9a5bd30e5c51f364ab5a9d11ceb7b 538 Gene3D G3DSA:3.40.1080.10 1 276 1.7E-80 T 23-10-2018 A3L01_08095 99c9a5bd30e5c51f364ab5a9d11ceb7b 538 Gene3D G3DSA:3.40.1080.10 286 537 7.8E-90 T 23-10-2018 A3L01_08095 99c9a5bd30e5c51f364ab5a9d11ceb7b 538 Pfam PF01144 Coenzyme A transferase 7 252 3.4E-31 T 23-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 A3L01_08095 99c9a5bd30e5c51f364ab5a9d11ceb7b 538 SUPERFAMILY SSF100950 286 536 8.37E-62 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L01_00020 a741f0b67e03968e0314624a45b0c693 200 Pfam PF02676 Methyltransferase TYW3 11 192 2.8E-45 T 23-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L01_00020 a741f0b67e03968e0314624a45b0c693 200 Gene3D G3DSA:3.30.1960.10 2 196 1.7E-66 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L01_00020 a741f0b67e03968e0314624a45b0c693 200 SUPERFAMILY SSF111278 7 192 6.93E-60 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L01_00020 a741f0b67e03968e0314624a45b0c693 200 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 9 195 30.172 T 23-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 A3L01_07085 47d87d228eb23c25058e6fdcfdfe1ae7 89 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 32 84 4.7E-15 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A3L01_03785 c90f4dd32a9555a484b1835c44e82b84 306 Pfam PF01384 Phosphate transporter family 15 298 1.3E-50 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A3L01_06825 92f5c87c5787f82a73a67526bfef9b0d 118 Gene3D G3DSA:3.40.1230.10 1 118 1.1E-35 T 23-10-2018 IPR036748 MTH938-like superfamily A3L01_06825 92f5c87c5787f82a73a67526bfef9b0d 118 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 7 115 3.9E-12 T 23-10-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein A3L01_06825 92f5c87c5787f82a73a67526bfef9b0d 118 SUPERFAMILY SSF64076 2 118 2.75E-34 T 23-10-2018 IPR036748 MTH938-like superfamily A3L01_01260 68348615b6475f171a7f5aaca388cce6 201 Gene3D G3DSA:3.40.50.10490 7 201 1.9E-71 T 23-10-2018 A3L01_01260 68348615b6475f171a7f5aaca388cce6 201 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 111 135 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A3L01_01260 68348615b6475f171a7f5aaca388cce6 201 Hamap MF_00291_A 30S ribosomal protein S2 [rpsB]. 1 198 48.239 T 23-10-2018 IPR023454 Ribosomal protein S2, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01260 68348615b6475f171a7f5aaca388cce6 201 Pfam PF00318 Ribosomal protein S2 12 104 1.7E-10 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01260 68348615b6475f171a7f5aaca388cce6 201 Pfam PF00318 Ribosomal protein S2 110 174 8.3E-14 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01260 68348615b6475f171a7f5aaca388cce6 201 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 8 19 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A3L01_01260 68348615b6475f171a7f5aaca388cce6 201 PRINTS PR00395 Ribosomal protein S2 signature 128 139 4.1E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01260 68348615b6475f171a7f5aaca388cce6 201 PRINTS PR00395 Ribosomal protein S2 signature 86 103 4.1E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01260 68348615b6475f171a7f5aaca388cce6 201 PRINTS PR00395 Ribosomal protein S2 signature 111 128 4.1E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01260 68348615b6475f171a7f5aaca388cce6 201 PRINTS PR00395 Ribosomal protein S2 signature 8 26 4.1E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01260 68348615b6475f171a7f5aaca388cce6 201 PRINTS PR00395 Ribosomal protein S2 signature 149 163 4.1E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01260 68348615b6475f171a7f5aaca388cce6 201 PRINTS PR00395 Ribosomal protein S2 signature 38 47 4.1E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01260 68348615b6475f171a7f5aaca388cce6 201 SUPERFAMILY SSF52313 3 192 6.28E-62 T 23-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily A3L01_01260 68348615b6475f171a7f5aaca388cce6 201 TIGRFAM TIGR01012 uS2_euk_arch: ribosomal protein uS2 3 197 3.8E-99 T 23-10-2018 IPR005707 Ribosomal protein S2, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_08725 ff3e760679b06b2efdd0bc0744f9769a 431 SUPERFAMILY SSF56762 18 380 1.7E-104 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_08725 ff3e760679b06b2efdd0bc0744f9769a 431 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 123 380 1.8E-60 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_08725 ff3e760679b06b2efdd0bc0744f9769a 431 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 47 72 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 A3L01_08725 ff3e760679b06b2efdd0bc0744f9769a 431 Pfam PF00374 Nickel-dependent hydrogenase 47 114 8.9E-14 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L01_08725 ff3e760679b06b2efdd0bc0744f9769a 431 Gene3D G3DSA:1.10.645.20 9 380 2.5E-123 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_02250 fdadeffcbb3f8a68cab8b43735b7d147 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 14 25 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_02250 fdadeffcbb3f8a68cab8b43735b7d147 67 Pfam PF00037 4Fe-4S binding domain 7 30 5.0E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_02250 fdadeffcbb3f8a68cab8b43735b7d147 67 Pfam PF00037 4Fe-4S binding domain 38 58 1.0E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_02250 fdadeffcbb3f8a68cab8b43735b7d147 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 43 54 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_02250 fdadeffcbb3f8a68cab8b43735b7d147 67 Gene3D G3DSA:3.30.70.20 36 65 4.5E-6 T 23-10-2018 A3L01_02250 fdadeffcbb3f8a68cab8b43735b7d147 67 SUPERFAMILY SSF54862 3 64 1.05E-17 T 23-10-2018 A3L01_02250 fdadeffcbb3f8a68cab8b43735b7d147 67 Gene3D G3DSA:3.30.70.20 1 35 5.5E-7 T 23-10-2018 A3L01_03965 3efd56e70f64dc452fd46e468172952c 76 Gene3D G3DSA:2.30.30.100 1 74 7.4E-23 T 23-10-2018 A3L01_03965 3efd56e70f64dc452fd46e468172952c 76 SMART SM00651 7 72 5.0E-19 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type A3L01_03965 3efd56e70f64dc452fd46e468172952c 76 Pfam PF01423 LSM domain 9 72 2.8E-18 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type A3L01_03965 3efd56e70f64dc452fd46e468172952c 76 SUPERFAMILY SSF50182 5 74 1.99E-17 T 23-10-2018 IPR010920 LSM domain superfamily A3L01_03965 3efd56e70f64dc452fd46e468172952c 76 Hamap MF_00257 Putative snRNP Sm-like protein. 1 72 25.206 T 23-10-2018 IPR022901 snRNP Sm-like, putative, archaea A3L01_08165 ec7cc9dd72bab6a369e3b78169573b33 118 Pfam PF02627 Carboxymuconolactone decarboxylase family 30 107 6.4E-19 T 23-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A3L01_08165 ec7cc9dd72bab6a369e3b78169573b33 118 SUPERFAMILY SSF69118 10 109 4.97E-27 T 23-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A3L01_08165 ec7cc9dd72bab6a369e3b78169573b33 118 Gene3D G3DSA:1.20.1290.10 1 118 2.1E-29 T 23-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A3L01_08165 ec7cc9dd72bab6a369e3b78169573b33 118 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 43 86 7.5E-13 T 23-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A3L01_02115 2b265059eb7782faf004987d12595322 832 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 110 692 2.3E-252 T 23-10-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A3L01_02115 2b265059eb7782faf004987d12595322 832 SUPERFAMILY SSF53756 17 725 2.87E-205 T 23-10-2018 A3L01_02115 2b265059eb7782faf004987d12595322 832 Pfam PF11897 Protein of unknown function (DUF3417) 16 123 3.3E-33 T 23-10-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A3L01_02115 2b265059eb7782faf004987d12595322 832 Gene3D G3DSA:3.40.50.2000 407 723 6.3E-43 T 23-10-2018 A3L01_02115 2b265059eb7782faf004987d12595322 832 Pfam PF00343 Carbohydrate phosphorylase 273 339 1.7E-4 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L01_02115 2b265059eb7782faf004987d12595322 832 Pfam PF00343 Carbohydrate phosphorylase 127 173 6.7E-5 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L01_02115 2b265059eb7782faf004987d12595322 832 Pfam PF00343 Carbohydrate phosphorylase 350 612 6.7E-22 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L01_02115 2b265059eb7782faf004987d12595322 832 PIRSF PIRSF000460 3 769 2.2E-273 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L01_02115 2b265059eb7782faf004987d12595322 832 Gene3D G3DSA:3.40.50.2000 270 406 8.2E-8 T 23-10-2018 A3L01_02115 2b265059eb7782faf004987d12595322 832 Gene3D G3DSA:3.40.50.2000 117 182 6.4E-11 T 23-10-2018 A3L01_02115 2b265059eb7782faf004987d12595322 832 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 586 598 - T 23-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L01_06050 894b1f57bf41063a4c81c65c26bbe45d 154 SMART SM00465 18 113 1.8E-7 T 23-10-2018 IPR000305 GIY-YIG endonuclease A3L01_06050 894b1f57bf41063a4c81c65c26bbe45d 154 Pfam PF01986 Domain of unknown function DUF123 25 110 1.3E-20 T 23-10-2018 IPR002837 Protein of unknown function DUF123 A3L01_00195 7a2e093326a1ae855cb804de4ad0b592 740 Gene3D G3DSA:1.50.10.20 110 218 2.4E-7 T 23-10-2018 A3L01_00195 7a2e093326a1ae855cb804de4ad0b592 740 Gene3D G3DSA:1.50.10.20 378 526 1.8E-13 T 23-10-2018 A3L01_00195 7a2e093326a1ae855cb804de4ad0b592 740 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 310 338 0.0065 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 A3L01_00195 7a2e093326a1ae855cb804de4ad0b592 740 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 444 484 5.5 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 A3L01_00195 7a2e093326a1ae855cb804de4ad0b592 740 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 76 101 0.0049 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 A3L01_00195 7a2e093326a1ae855cb804de4ad0b592 740 SUPERFAMILY SSF48239 309 517 1.36E-20 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L01_00195 7a2e093326a1ae855cb804de4ad0b592 740 Gene3D G3DSA:1.50.10.20 277 362 1.3E-6 T 23-10-2018 A3L01_00195 7a2e093326a1ae855cb804de4ad0b592 740 Gene3D G3DSA:1.50.10.20 40 109 4.3E-9 T 23-10-2018 A3L01_00195 7a2e093326a1ae855cb804de4ad0b592 740 SUPERFAMILY SSF48239 27 180 4.93E-23 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L01_03380 19489d20ce661de5f961511f34e768cc 127 Pfam PF01042 Endoribonuclease L-PSP 9 126 1.6E-43 T 23-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 A3L01_03380 19489d20ce661de5f961511f34e768cc 127 SUPERFAMILY SSF55298 1 127 2.51E-45 T 23-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A3L01_03380 19489d20ce661de5f961511f34e768cc 127 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 103 121 - T 23-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 A3L01_03380 19489d20ce661de5f961511f34e768cc 127 Gene3D G3DSA:3.30.1330.40 1 127 9.9E-52 T 23-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A3L01_03380 19489d20ce661de5f961511f34e768cc 127 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 4 126 1.8E-50 T 23-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 A3L01_02320 1895f4c1b2bcd0d0ccfb5842b46c9879 257 PIRSF PIRSF005054 2 243 1.3E-63 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L01_02320 1895f4c1b2bcd0d0ccfb5842b46c9879 257 Gene3D G3DSA:3.30.70.1900 124 241 4.3E-35 T 23-10-2018 A3L01_02320 1895f4c1b2bcd0d0ccfb5842b46c9879 257 Gene3D G3DSA:3.30.70.1890 1 123 4.4E-38 T 23-10-2018 A3L01_02320 1895f4c1b2bcd0d0ccfb5842b46c9879 257 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 44 239 1.3E-46 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L01_02320 1895f4c1b2bcd0d0ccfb5842b46c9879 257 Pfam PF01881 CRISPR associated protein Cas6 96 239 1.3E-31 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L01_05115 32c46f8d51a821d30492fd0c9949a392 209 Gene3D G3DSA:1.10.287.1080 120 209 8.8E-26 T 23-10-2018 A3L01_05115 32c46f8d51a821d30492fd0c9949a392 209 SUPERFAMILY SSF141734 5 114 5.1E-43 T 23-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 A3L01_05115 32c46f8d51a821d30492fd0c9949a392 209 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 8 209 35.72 T 23-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 A3L01_05115 32c46f8d51a821d30492fd0c9949a392 209 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 33 105 1.1E-31 T 23-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A3L01_05115 32c46f8d51a821d30492fd0c9949a392 209 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 55 108 2.0E-21 T 23-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A3L01_05115 32c46f8d51a821d30492fd0c9949a392 209 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 124 207 1.2E-13 T 23-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 A3L01_05115 32c46f8d51a821d30492fd0c9949a392 209 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 124 204 1.1E-27 T 23-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A3L01_05115 32c46f8d51a821d30492fd0c9949a392 209 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 7 109 29.402 T 23-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A3L01_05115 32c46f8d51a821d30492fd0c9949a392 209 SUPERFAMILY SSF101386 123 208 1.59E-21 T 23-10-2018 A3L01_05115 32c46f8d51a821d30492fd0c9949a392 209 Gene3D G3DSA:3.10.20.400 3 96 8.2E-35 T 23-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 A3L01_05115 32c46f8d51a821d30492fd0c9949a392 209 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 121 204 18.56 T 23-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A3L01_01325 08b5c3e830be89c767fccfd947bcceb0 448 Gene3D G3DSA:1.20.120.140 6 300 2.1E-122 T 23-10-2018 A3L01_01325 08b5c3e830be89c767fccfd947bcceb0 448 SUPERFAMILY SSF47364 1 94 1.57E-22 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 A3L01_01325 08b5c3e830be89c767fccfd947bcceb0 448 Pfam PF02978 Signal peptide binding domain 327 425 7.0E-35 T 23-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L01_01325 08b5c3e830be89c767fccfd947bcceb0 448 SMART SM00963 2 87 1.6E-22 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L01_01325 08b5c3e830be89c767fccfd947bcceb0 448 SMART SM00382 99 300 2.7E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_01325 08b5c3e830be89c767fccfd947bcceb0 448 SUPERFAMILY SSF52540 96 297 3.43E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_01325 08b5c3e830be89c767fccfd947bcceb0 448 Pfam PF00448 SRP54-type protein, GTPase domain 100 295 1.1E-75 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L01_01325 08b5c3e830be89c767fccfd947bcceb0 448 Gene3D G3DSA:1.10.260.30 301 430 6.6E-45 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L01_01325 08b5c3e830be89c767fccfd947bcceb0 448 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 1.6E-19 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L01_01325 08b5c3e830be89c767fccfd947bcceb0 448 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 268 281 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L01_01325 08b5c3e830be89c767fccfd947bcceb0 448 SUPERFAMILY SSF47446 297 429 1.15E-43 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L01_01325 08b5c3e830be89c767fccfd947bcceb0 448 Gene3D G3DSA:3.40.50.300 91 284 2.1E-122 T 23-10-2018 A3L01_01325 08b5c3e830be89c767fccfd947bcceb0 448 SMART SM00962 100 295 2.2E-100 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L01_01325 08b5c3e830be89c767fccfd947bcceb0 448 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 438 38.168 T 23-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 A3L01_00560 6f7efedd28dfe7acb0722079062c1679 340 Gene3D G3DSA:3.40.50.300 3 236 2.2E-74 T 23-10-2018 A3L01_00560 6f7efedd28dfe7acb0722079062c1679 340 Pfam PF00005 ABC transporter 22 160 8.6E-35 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_00560 6f7efedd28dfe7acb0722079062c1679 340 SMART SM00382 27 210 1.4E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_00560 6f7efedd28dfe7acb0722079062c1679 340 SUPERFAMILY SSF52540 4 241 3.25E-87 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_00560 6f7efedd28dfe7acb0722079062c1679 340 SUPERFAMILY SSF50331 237 315 5.16E-5 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L01_00560 6f7efedd28dfe7acb0722079062c1679 340 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_09325 d3c5b906f7b2adad5e863a725d94ab58 200 Gene3D G3DSA:3.40.630.20 1 200 1.5E-74 T 23-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 A3L01_09325 d3c5b906f7b2adad5e863a725d94ab58 200 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 67 83 - T 23-10-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site MetaCyc: PWY-7942 A3L01_09325 d3c5b906f7b2adad5e863a725d94ab58 200 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 128 142 - T 23-10-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site MetaCyc: PWY-7942 A3L01_09325 d3c5b906f7b2adad5e863a725d94ab58 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 60 72 1.4E-41 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L01_09325 d3c5b906f7b2adad5e863a725d94ab58 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 78 98 1.4E-41 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L01_09325 d3c5b906f7b2adad5e863a725d94ab58 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 160 172 1.4E-41 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L01_09325 d3c5b906f7b2adad5e863a725d94ab58 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 3 26 1.4E-41 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L01_09325 d3c5b906f7b2adad5e863a725d94ab58 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 130 146 1.4E-41 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L01_09325 d3c5b906f7b2adad5e863a725d94ab58 200 PIRSF PIRSF015592 1 200 3.7E-76 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L01_09325 d3c5b906f7b2adad5e863a725d94ab58 200 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 2 198 4.5E-75 T 23-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 A3L01_09325 d3c5b906f7b2adad5e863a725d94ab58 200 SUPERFAMILY SSF53182 1 198 5.89E-68 T 23-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 A3L01_09325 d3c5b906f7b2adad5e863a725d94ab58 200 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 1 198 37.314 T 23-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 A3L01_09325 d3c5b906f7b2adad5e863a725d94ab58 200 Pfam PF01470 Pyroglutamyl peptidase 1 198 2.0E-75 T 23-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 A3L01_07380 82044f30eb59cf019fdfdac78b125e40 353 Gene3D G3DSA:3.30.230.10 2 179 1.7E-56 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L01_07380 82044f30eb59cf019fdfdac78b125e40 353 Pfam PF08544 GHMP kinases C terminal 249 325 1.6E-12 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain A3L01_07380 82044f30eb59cf019fdfdac78b125e40 353 SUPERFAMILY SSF55060 180 348 9.89E-43 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A3L01_07380 82044f30eb59cf019fdfdac78b125e40 353 Gene3D G3DSA:3.30.70.890 180 350 1.3E-57 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A3L01_07380 82044f30eb59cf019fdfdac78b125e40 353 SUPERFAMILY SSF54211 2 178 1.44E-50 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L01_07380 82044f30eb59cf019fdfdac78b125e40 353 PRINTS PR00473 Galactokinase signature 8 26 7.6E-21 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L01_07380 82044f30eb59cf019fdfdac78b125e40 353 PRINTS PR00473 Galactokinase signature 67 78 7.6E-21 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L01_07380 82044f30eb59cf019fdfdac78b125e40 353 PRINTS PR00473 Galactokinase signature 234 248 7.6E-21 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L01_07380 82044f30eb59cf019fdfdac78b125e40 353 PRINTS PR00473 Galactokinase signature 87 105 7.6E-21 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L01_07380 82044f30eb59cf019fdfdac78b125e40 353 ProSitePatterns PS00106 Galactokinase signature. 8 19 - T 23-10-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L01_07380 82044f30eb59cf019fdfdac78b125e40 353 Hamap MF_00246 Galactokinase [galK]. 6 350 39.042 T 23-10-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L01_07380 82044f30eb59cf019fdfdac78b125e40 353 Pfam PF10509 Galactokinase galactose-binding signature 4 38 1.0E-15 T 23-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L01_07380 82044f30eb59cf019fdfdac78b125e40 353 PRINTS PR00959 Mevalonate kinase family signature 94 116 1.4E-40 T 23-10-2018 A3L01_07380 82044f30eb59cf019fdfdac78b125e40 353 PRINTS PR00959 Mevalonate kinase family signature 6 30 1.4E-40 T 23-10-2018 A3L01_07380 82044f30eb59cf019fdfdac78b125e40 353 PRINTS PR00959 Mevalonate kinase family signature 137 156 1.4E-40 T 23-10-2018 A3L01_07380 82044f30eb59cf019fdfdac78b125e40 353 PRINTS PR00959 Mevalonate kinase family signature 297 314 1.4E-40 T 23-10-2018 A3L01_07380 82044f30eb59cf019fdfdac78b125e40 353 PIRSF PIRSF000530 1 353 8.2E-104 T 23-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L01_07380 82044f30eb59cf019fdfdac78b125e40 353 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 96 107 - T 23-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 A3L01_07380 82044f30eb59cf019fdfdac78b125e40 353 Pfam PF00288 GHMP kinases N terminal domain 92 156 6.2E-15 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A3L01_07380 82044f30eb59cf019fdfdac78b125e40 353 TIGRFAM TIGR00131 gal_kin: galactokinase 3 348 4.0E-80 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L01_01185 a0bd8cc60d219bdb334fac95d35a619a 334 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 240 320 1.4E-9 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L01_01185 a0bd8cc60d219bdb334fac95d35a619a 334 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 247 2.3E-23 T 23-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A3L01_01185 a0bd8cc60d219bdb334fac95d35a619a 334 SMART SM00359 251 325 6.8E-22 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L01_01185 a0bd8cc60d219bdb334fac95d35a619a 334 Pfam PF08068 DKCLD (NUC011) domain 15 63 9.0E-19 T 23-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A3L01_01185 a0bd8cc60d219bdb334fac95d35a619a 334 Gene3D G3DSA:2.30.130.70 23 332 1.8E-146 T 23-10-2018 A3L01_01185 a0bd8cc60d219bdb334fac95d35a619a 334 Hamap MF_01081 Probable tRNA pseudouridine synthase B [truB]. 40 325 51.382 T 23-10-2018 IPR026326 Probable tRNA pseudouridine synthase B, archaeal GO:0006396 A3L01_01185 a0bd8cc60d219bdb334fac95d35a619a 334 SMART SM01136 4 63 9.5E-26 T 23-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A3L01_01185 a0bd8cc60d219bdb334fac95d35a619a 334 Gene3D G3DSA:3.30.2350.10 40 243 1.8E-146 T 23-10-2018 A3L01_01185 a0bd8cc60d219bdb334fac95d35a619a 334 SUPERFAMILY SSF88697 249 332 1.05E-22 T 23-10-2018 IPR015947 PUA-like superfamily A3L01_01185 a0bd8cc60d219bdb334fac95d35a619a 334 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 121 180 1.2E-6 T 23-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 A3L01_01185 a0bd8cc60d219bdb334fac95d35a619a 334 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 67 118 2.4E-15 T 23-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 A3L01_01185 a0bd8cc60d219bdb334fac95d35a619a 334 TIGRFAM TIGR00425 CBF5: putative rRNA pseudouridine synthase 18 334 2.7E-135 T 23-10-2018 IPR004802 tRNA pseudouridine synthase B family GO:0006396 Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A3L01_01185 a0bd8cc60d219bdb334fac95d35a619a 334 SUPERFAMILY SSF55120 19 247 4.08E-77 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L01_01185 a0bd8cc60d219bdb334fac95d35a619a 334 Pfam PF01472 PUA domain 251 323 4.2E-20 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L01_02370 c1239f2d033458aa74551f3a3db5ea9f 406 SUPERFAMILY SSF53697 215 404 3.44E-40 T 23-10-2018 A3L01_02370 c1239f2d033458aa74551f3a3db5ea9f 406 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 3 206 6.2E-83 T 23-10-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 A3L01_02370 c1239f2d033458aa74551f3a3db5ea9f 406 Pfam PF01380 SIS domain 246 347 2.5E-21 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A3L01_02370 c1239f2d033458aa74551f3a3db5ea9f 406 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 3 203 3.0E-27 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L01_02370 c1239f2d033458aa74551f3a3db5ea9f 406 SUPERFAMILY SSF51366 2 214 4.04E-45 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L01_02370 c1239f2d033458aa74551f3a3db5ea9f 406 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 219 406 3.2E-75 T 23-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 A3L01_02370 c1239f2d033458aa74551f3a3db5ea9f 406 Gene3D G3DSA:3.20.20.70 1 208 9.7E-76 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_02370 c1239f2d033458aa74551f3a3db5ea9f 406 Gene3D G3DSA:3.40.50.10490 213 406 1.0E-59 T 23-10-2018 A3L01_02370 c1239f2d033458aa74551f3a3db5ea9f 406 SMART SM00934 2 203 1.1E-44 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L01_01745 4bf8f63439fc53b9dad80147e1dc45ae 344 SUPERFAMILY SSF81345 7 339 1.96E-84 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L01_01745 4bf8f63439fc53b9dad80147e1dc45ae 344 Pfam PF01032 FecCD transport family 21 339 2.7E-95 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A3L01_01745 4bf8f63439fc53b9dad80147e1dc45ae 344 Gene3D G3DSA:1.10.3470.10 9 343 1.2E-104 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L01_02100 507ca16681b0e3b3c24e422a65e98791 235 SUPERFAMILY SSF53738 128 207 5.1E-6 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_02100 507ca16681b0e3b3c24e422a65e98791 235 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 8 68 4.1E-5 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_02100 507ca16681b0e3b3c24e422a65e98791 235 SUPERFAMILY SSF53738 8 76 8.63E-7 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_02100 507ca16681b0e3b3c24e422a65e98791 235 Gene3D G3DSA:3.40.120.10 3 78 3.6E-6 T 23-10-2018 A3L01_03920 54b175cef6f57f69d3e87c0bb16d6d1b 904 Gene3D G3DSA:3.40.50.880 668 892 1.2E-12 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_03920 54b175cef6f57f69d3e87c0bb16d6d1b 904 Pfam PF09822 ABC-type uncharacterized transport system 679 780 2.6E-11 T 23-10-2018 IPR019196 ABC-type uncharacterised transport system Reactome: R-HSA-5610787|Reactome: R-HSA-5620924 A3L01_03920 54b175cef6f57f69d3e87c0bb16d6d1b 904 SUPERFAMILY SSF52317 660 902 1.12E-26 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_03920 54b175cef6f57f69d3e87c0bb16d6d1b 904 ProDom PD117176 AQ_1776 673 793 9.0E-4 T 23-10-2018 A3L01_03625 58a77da5cc7aa3d066db3f328a004a4b 141 Pfam PF02996 Prefoldin subunit 20 133 9.6E-21 T 23-10-2018 IPR004127 Prefoldin alpha-like A3L01_03625 58a77da5cc7aa3d066db3f328a004a4b 141 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 3 137 14.017 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 A3L01_03625 58a77da5cc7aa3d066db3f328a004a4b 141 Gene3D G3DSA:1.10.287.370 9 138 6.6E-32 T 23-10-2018 IPR009053 Prefoldin A3L01_03625 58a77da5cc7aa3d066db3f328a004a4b 141 SUPERFAMILY SSF46579 9 137 4.71E-22 T 23-10-2018 A3L01_03625 58a77da5cc7aa3d066db3f328a004a4b 141 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 9 134 1.2E-23 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 A3L01_01445 12ef3e79866d59d40b329be465ab3926 522 Pfam PF07969 Amidohydrolase family 50 520 5.3E-123 T 23-10-2018 IPR013108 Amidohydrolase 3 A3L01_01445 12ef3e79866d59d40b329be465ab3926 522 SUPERFAMILY SSF51556 60 477 1.41E-42 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L01_01445 12ef3e79866d59d40b329be465ab3926 522 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 62 70 - T 23-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A3L01_01445 12ef3e79866d59d40b329be465ab3926 522 Gene3D G3DSA:3.10.310.70 79 193 2.7E-155 T 23-10-2018 A3L01_01445 12ef3e79866d59d40b329be465ab3926 522 Gene3D G3DSA:2.30.40.10 7 495 2.7E-155 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L01_01445 12ef3e79866d59d40b329be465ab3926 522 Gene3D G3DSA:3.20.20.140 61 479 2.7E-155 T 23-10-2018 A3L01_01445 12ef3e79866d59d40b329be465ab3926 522 SUPERFAMILY SSF51338 6 520 1.25E-10 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L01_00125 89a8d7433f84204307696411472491d3 713 Pfam PF02769 AIR synthase related protein, C-terminal domain 552 680 4.0E-19 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L01_00125 89a8d7433f84204307696411472491d3 713 Pfam PF02769 AIR synthase related protein, C-terminal domain 185 339 1.7E-36 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L01_00125 89a8d7433f84204307696411472491d3 713 PIRSF PIRSF001587 1 712 4.4E-278 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L01_00125 89a8d7433f84204307696411472491d3 713 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 2 703 1.7E-288 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L01_00125 89a8d7433f84204307696411472491d3 713 SUPERFAMILY SSF56042 184 402 8.22E-51 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L01_00125 89a8d7433f84204307696411472491d3 713 SUPERFAMILY SSF56042 544 704 5.23E-35 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L01_00125 89a8d7433f84204307696411472491d3 713 Gene3D G3DSA:3.90.650.10 543 709 3.2E-35 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L01_00125 89a8d7433f84204307696411472491d3 713 SUPERFAMILY SSF55326 377 534 5.23E-48 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L01_00125 89a8d7433f84204307696411472491d3 713 SUPERFAMILY SSF55326 19 178 4.93E-48 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L01_00125 89a8d7433f84204307696411472491d3 713 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 713 251.243 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L01_00125 89a8d7433f84204307696411472491d3 713 Gene3D G3DSA:3.90.650.10 12 339 1.3E-120 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L01_00125 89a8d7433f84204307696411472491d3 713 Gene3D G3DSA:3.30.1330.10 364 536 8.6E-54 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L01_00125 89a8d7433f84204307696411472491d3 713 Gene3D G3DSA:3.30.1330.10 27 175 1.3E-120 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L01_00125 89a8d7433f84204307696411472491d3 713 Pfam PF00586 AIR synthase related protein, N-terminal domain 417 533 1.1E-19 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L01_00125 89a8d7433f84204307696411472491d3 713 Pfam PF00586 AIR synthase related protein, N-terminal domain 59 172 1.1E-24 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L01_07035 f136d5558300ee0db5242d28ce32c953 81 SUPERFAMILY SSF54909 2 76 1.74E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L01_07035 f136d5558300ee0db5242d28ce32c953 81 Gene3D G3DSA:3.30.70.920 2 74 4.6E-21 T 23-10-2018 A3L01_07035 f136d5558300ee0db5242d28ce32c953 81 Pfam PF01037 Lrp/AsnC ligand binding domain 6 76 9.5E-16 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L01_10250 d3b26e57937fca6a2290e7d80c9ae14f 280 Gene3D G3DSA:2.60.40.10 89 177 1.5E-11 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_10250 d3b26e57937fca6a2290e7d80c9ae14f 280 Gene3D G3DSA:2.60.40.10 178 266 8.3E-11 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_10250 d3b26e57937fca6a2290e7d80c9ae14f 280 Gene3D G3DSA:2.60.40.10 2 76 6.5E-10 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_10250 d3b26e57937fca6a2290e7d80c9ae14f 280 SUPERFAMILY SSF49373 93 173 3.92E-10 T 23-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments A3L01_10250 d3b26e57937fca6a2290e7d80c9ae14f 280 SMART SM00634 179 270 0.11 T 23-10-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain A3L01_10250 d3b26e57937fca6a2290e7d80c9ae14f 280 SMART SM00634 3 80 0.23 T 23-10-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain A3L01_10250 d3b26e57937fca6a2290e7d80c9ae14f 280 SMART SM00634 90 175 7.4E-5 T 23-10-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain A3L01_10250 d3b26e57937fca6a2290e7d80c9ae14f 280 SUPERFAMILY SSF49373 11 72 9.94E-9 T 23-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments A3L01_10250 d3b26e57937fca6a2290e7d80c9ae14f 280 SUPERFAMILY SSF49373 199 263 1.1E-8 T 23-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments A3L01_10250 d3b26e57937fca6a2290e7d80c9ae14f 280 Pfam PF16640 Bacterial Ig-like domain (group 3) 195 278 2.8E-11 T 23-10-2018 IPR032109 Bacterial Ig-like domain (group 3) A3L01_10250 d3b26e57937fca6a2290e7d80c9ae14f 280 Pfam PF16640 Bacterial Ig-like domain (group 3) 7 83 2.8E-9 T 23-10-2018 IPR032109 Bacterial Ig-like domain (group 3) A3L01_10250 d3b26e57937fca6a2290e7d80c9ae14f 280 Pfam PF16640 Bacterial Ig-like domain (group 3) 99 181 4.4E-9 T 23-10-2018 IPR032109 Bacterial Ig-like domain (group 3) A3L01_00105 1da2c5f2529fad831e322d27eeb066bc 438 SUPERFAMILY SSF56059 103 323 4.07E-48 T 23-10-2018 A3L01_00105 1da2c5f2529fad831e322d27eeb066bc 438 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 102 296 2.6E-60 T 23-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L01_00105 1da2c5f2529fad831e322d27eeb066bc 438 Gene3D G3DSA:3.40.50.20 2 94 1.1E-19 T 23-10-2018 A3L01_00105 1da2c5f2529fad831e322d27eeb066bc 438 SMART SM01210 328 418 4.3E-16 T 23-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L01_00105 1da2c5f2529fad831e322d27eeb066bc 438 Gene3D G3DSA:3.90.600.10 329 415 1.1E-7 T 23-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L01_00105 1da2c5f2529fad831e322d27eeb066bc 438 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 290 297 - T 23-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L01_00105 1da2c5f2529fad831e322d27eeb066bc 438 SUPERFAMILY SSF51246 326 416 1.26E-14 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A3L01_00105 1da2c5f2529fad831e322d27eeb066bc 438 SUPERFAMILY SSF52440 1 102 1.27E-23 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L01_00105 1da2c5f2529fad831e322d27eeb066bc 438 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 101 4.0E-21 T 23-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L01_00105 1da2c5f2529fad831e322d27eeb066bc 438 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 330 416 1.5E-12 T 23-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L01_00105 1da2c5f2529fad831e322d27eeb066bc 438 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 418 36.092 T 23-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L01_00105 1da2c5f2529fad831e322d27eeb066bc 438 SMART SM01209 102 296 1.1E-94 T 23-10-2018 A3L01_00105 1da2c5f2529fad831e322d27eeb066bc 438 Gene3D G3DSA:3.30.470.20 189 328 8.8E-48 T 23-10-2018 A3L01_00105 1da2c5f2529fad831e322d27eeb066bc 438 Gene3D G3DSA:3.30.1490.20 121 187 4.4E-15 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L01_00105 1da2c5f2529fad831e322d27eeb066bc 438 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 417 1.1E-145 T 23-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L01_07050 fa2bc9c2f4d797f1ae6a795a58d0cf74 253 PIRSF PIRSF017269 1 253 2.1E-79 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 A3L01_07050 fa2bc9c2f4d797f1ae6a795a58d0cf74 253 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 74 234 2.1E-27 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 A3L01_07050 fa2bc9c2f4d797f1ae6a795a58d0cf74 253 SUPERFAMILY SSF53335 2 252 2.3E-76 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_07050 fa2bc9c2f4d797f1ae6a795a58d0cf74 253 Gene3D G3DSA:3.40.50.150 63 253 1.4E-67 T 23-10-2018 A3L01_07050 fa2bc9c2f4d797f1ae6a795a58d0cf74 253 Gene3D G3DSA:3.10.330.20 1 61 1.8E-23 T 23-10-2018 A3L01_05210 fefb8eb18723b44826e4f3346f0719c5 339 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 339 96.486 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L01_05210 fefb8eb18723b44826e4f3346f0719c5 339 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 23-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L01_05210 fefb8eb18723b44826e4f3346f0719c5 339 Gene3D G3DSA:3.40.440.10 1 339 3.6E-137 T 23-10-2018 A3L01_05210 fefb8eb18723b44826e4f3346f0719c5 339 Pfam PF00709 Adenylosuccinate synthetase 147 290 3.3E-44 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L01_05210 fefb8eb18723b44826e4f3346f0719c5 339 Pfam PF00709 Adenylosuccinate synthetase 5 144 1.5E-36 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L01_05210 fefb8eb18723b44826e4f3346f0719c5 339 SUPERFAMILY SSF52540 1 335 4.57E-107 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_05210 fefb8eb18723b44826e4f3346f0719c5 339 SMART SM00788 3 334 3.9E-155 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L01_08900 2b838a2f50e721f480c6c184e011bac9 184 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 181 40.415 T 23-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 A3L01_08900 2b838a2f50e721f480c6c184e011bac9 184 SUPERFAMILY SSF52972 1 182 4.19E-60 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L01_08900 2b838a2f50e721f480c6c184e011bac9 184 Gene3D G3DSA:3.90.950.10 1 184 5.0E-71 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L01_08900 2b838a2f50e721f480c6c184e011bac9 184 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 179 3.7E-60 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 A3L01_08900 2b838a2f50e721f480c6c184e011bac9 184 Pfam PF01725 Ham1 family 3 178 1.3E-48 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 A3L01_08225 1793dcf2f884c08280b8c0f11e48b8bb 350 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 335 5.2E-34 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L01_08225 1793dcf2f884c08280b8c0f11e48b8bb 350 SUPERFAMILY SSF51971 17 282 3.88E-54 T 23-10-2018 A3L01_08225 1793dcf2f884c08280b8c0f11e48b8bb 350 Gene3D G3DSA:3.50.50.60 131 282 8.9E-54 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_08225 1793dcf2f884c08280b8c0f11e48b8bb 350 Gene3D G3DSA:3.50.50.60 22 341 8.9E-54 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_08225 1793dcf2f884c08280b8c0f11e48b8bb 350 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 20 42 4.4E-16 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L01_08225 1793dcf2f884c08280b8c0f11e48b8bb 350 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 169 193 4.4E-16 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L01_08225 1793dcf2f884c08280b8c0f11e48b8bb 350 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 310 328 4.4E-16 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L01_08225 1793dcf2f884c08280b8c0f11e48b8bb 350 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 3.3E-16 T 23-10-2018 A3L01_08225 1793dcf2f884c08280b8c0f11e48b8bb 350 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 3.3E-16 T 23-10-2018 A3L01_08225 1793dcf2f884c08280b8c0f11e48b8bb 350 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 300 322 3.3E-16 T 23-10-2018 A3L01_03930 247667e2440b0c247c6ffb67882df27f 252 Hamap MF_00226_A Putative competence-damage inducible protein [cinA]. 1 249 38.676 T 23-10-2018 IPR023055 Putative competence-damage inducible protein, Archaea A3L01_03930 247667e2440b0c247c6ffb67882df27f 252 SMART SM00852 4 179 7.0E-41 T 23-10-2018 IPR001453 MoaB/Mog domain A3L01_03930 247667e2440b0c247c6ffb67882df27f 252 SUPERFAMILY SSF53218 1 205 2.88E-41 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L01_03930 247667e2440b0c247c6ffb67882df27f 252 Gene3D G3DSA:3.40.980.10 2 179 6.0E-55 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L01_03930 247667e2440b0c247c6ffb67882df27f 252 Pfam PF00994 Probable molybdopterin binding domain 4 176 3.8E-35 T 23-10-2018 IPR001453 MoaB/Mog domain A3L01_08595 f1252ee01fbf3b20258e68915bbd328e 987 Gene3D G3DSA:2.40.50.140 907 986 2.0E-5 T 23-10-2018 A3L01_08595 f1252ee01fbf3b20258e68915bbd328e 987 SUPERFAMILY SSF50249 913 984 5.14E-7 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_08595 f1252ee01fbf3b20258e68915bbd328e 987 Pfam PF01336 OB-fold nucleic acid binding domain 364 434 2.0E-6 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L01_08595 f1252ee01fbf3b20258e68915bbd328e 987 Pfam PF01336 OB-fold nucleic acid binding domain 915 977 1.3E-7 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L01_08595 f1252ee01fbf3b20258e68915bbd328e 987 Gene3D G3DSA:2.40.50.140 354 445 1.0E-5 T 23-10-2018 A3L01_08595 f1252ee01fbf3b20258e68915bbd328e 987 SUPERFAMILY SSF50249 362 436 2.36E-6 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_05630 49a931f3c023efa628e52e19088bd076 474 TIGRFAM TIGR02751 PEPCase_arch: phosphoenolpyruvate carboxylase 2 438 1.9E-179 T 23-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A3L01_05630 49a931f3c023efa628e52e19088bd076 474 Pfam PF14010 Phosphoenolpyruvate carboxylase 2 454 3.0E-170 T 23-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A3L01_05630 49a931f3c023efa628e52e19088bd076 474 Hamap MF_01904 Phosphoenolpyruvate carboxylase [ppcA]. 1 474 38.685 T 23-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A3L01_05630 49a931f3c023efa628e52e19088bd076 474 SUPERFAMILY SSF51621 95 425 5.23E-39 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A3L01_05630 49a931f3c023efa628e52e19088bd076 474 PIRSF PIRSF006677 1 474 8.5E-178 T 23-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A3L01_04555 e8ea0b6098998b9a5a925e014c242187 102 PRINTS PR00971 Ribosomal protein S10 family signature 3 16 2.3E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_04555 e8ea0b6098998b9a5a925e014c242187 102 PRINTS PR00971 Ribosomal protein S10 family signature 60 74 2.3E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_04555 e8ea0b6098998b9a5a925e014c242187 102 PRINTS PR00971 Ribosomal protein S10 family signature 38 53 2.3E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_04555 e8ea0b6098998b9a5a925e014c242187 102 SUPERFAMILY SSF54999 3 100 4.84E-29 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily A3L01_04555 e8ea0b6098998b9a5a925e014c242187 102 Gene3D G3DSA:3.30.70.600 1 101 8.7E-35 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily A3L01_04555 e8ea0b6098998b9a5a925e014c242187 102 TIGRFAM TIGR01046 uS10_euk_arch: ribosomal protein uS10 2 100 3.5E-50 T 23-10-2018 IPR005729 Ribosomal protein S10, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_04555 e8ea0b6098998b9a5a925e014c242187 102 SMART SM01403 5 99 1.7E-40 T 23-10-2018 IPR027486 Ribosomal protein S10 domain A3L01_04555 e8ea0b6098998b9a5a925e014c242187 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 1 100 24.613 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_04555 e8ea0b6098998b9a5a925e014c242187 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 27 42 - T 23-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_04555 e8ea0b6098998b9a5a925e014c242187 102 Pfam PF00338 Ribosomal protein S10p/S20e 5 98 1.4E-27 T 23-10-2018 IPR027486 Ribosomal protein S10 domain A3L01_09200 5e9f7ab16d8841bc6ecc3c953144afbb 225 Gene3D G3DSA:3.90.850.10 5 221 7.4E-92 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A3L01_09200 5e9f7ab16d8841bc6ecc3c953144afbb 225 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 17 217 4.3E-71 T 23-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 A3L01_09200 5e9f7ab16d8841bc6ecc3c953144afbb 225 SUPERFAMILY SSF56529 13 218 8.9E-84 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A3L01_01630 84ca2520dd6cf0eb9970c46e35dd57ec 414 SUPERFAMILY SSF103473 37 411 1.83E-33 T 23-10-2018 IPR036259 MFS transporter superfamily A3L01_01630 84ca2520dd6cf0eb9970c46e35dd57ec 414 Gene3D G3DSA:1.20.1250.20 28 413 6.5E-33 T 23-10-2018 A3L01_01630 84ca2520dd6cf0eb9970c46e35dd57ec 414 Pfam PF07690 Major Facilitator Superfamily 43 381 1.4E-22 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L01_00240 9e59e8496a16aaca2c9bc8eb734882cc 62 SUPERFAMILY SSF63393 3 62 3.92E-23 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A3L01_00240 9e59e8496a16aaca2c9bc8eb734882cc 62 Hamap MF_00949 Transcription elongation factor Spt4 [spt4]. 6 62 28.993 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 A3L01_00240 9e59e8496a16aaca2c9bc8eb734882cc 62 SMART SM01389 4 62 3.4E-31 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A3L01_00240 9e59e8496a16aaca2c9bc8eb734882cc 62 Gene3D G3DSA:2.20.28.90 1 62 1.1E-32 T 23-10-2018 IPR038589 Archaeal transcription elongation factor Spt4 superfamily A3L01_00240 9e59e8496a16aaca2c9bc8eb734882cc 62 ProDom PD019197 RNA DNA-DIRECTED POLYMERASE SUBUNIT E'' POLYMERASE RPOE2 TRANSFERASE NUCLEOTIDYLTRANSFERASE E 19 61 7.0E-15 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 A3L01_00240 9e59e8496a16aaca2c9bc8eb734882cc 62 Pfam PF06093 Spt4/RpoE2 zinc finger 4 62 6.6E-17 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A3L01_00065 b94146f1eaacaab8665c549e97ade294 666 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 7 659 1.6E-265 T 23-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 A3L01_00065 b94146f1eaacaab8665c549e97ade294 666 Pfam PF01568 Molydopterin dinucleotide binding domain 555 653 1.8E-23 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A3L01_00065 b94146f1eaacaab8665c549e97ade294 666 SUPERFAMILY SSF53706 6 557 1.3E-197 T 23-10-2018 A3L01_00065 b94146f1eaacaab8665c549e97ade294 666 Gene3D G3DSA:3.40.50.740 62 519 7.8E-172 T 23-10-2018 A3L01_00065 b94146f1eaacaab8665c549e97ade294 666 Pfam PF00384 Molybdopterin oxidoreductase 55 474 1.9E-90 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_00065 b94146f1eaacaab8665c549e97ade294 666 Gene3D G3DSA:2.20.25.90 5 52 2.5E-9 T 23-10-2018 A3L01_00065 b94146f1eaacaab8665c549e97ade294 666 Gene3D G3DSA:2.40.40.20 542 665 1.0E-35 T 23-10-2018 A3L01_00065 b94146f1eaacaab8665c549e97ade294 666 SUPERFAMILY SSF50692 527 661 4.14E-38 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L01_00065 b94146f1eaacaab8665c549e97ade294 666 Gene3D G3DSA:3.40.228.10 132 329 7.8E-172 T 23-10-2018 A3L01_00065 b94146f1eaacaab8665c549e97ade294 666 SMART SM00926 2 52 1.1E-9 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_00065 b94146f1eaacaab8665c549e97ade294 666 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 8 50 6.0E-9 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_01950 cc5331583176bbe2f772d515e24f9fad 391 Gene3D G3DSA:1.10.150.390 333 378 6.4E-23 T 23-10-2018 A3L01_01950 cc5331583176bbe2f772d515e24f9fad 391 SUPERFAMILY SSF64484 30 385 1.49E-106 T 23-10-2018 A3L01_01950 cc5331583176bbe2f772d515e24f9fad 391 Hamap MF_00411 DNA-directed RNA polymerase subunit A'' [rpoA2]. 3 385 41.235 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01950 cc5331583176bbe2f772d515e24f9fad 391 Pfam PF04998 RNA polymerase Rpb1, domain 5 50 332 7.3E-57 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01950 cc5331583176bbe2f772d515e24f9fad 391 TIGRFAM TIGR02389 RNA_pol_rpoA2: DNA-directed RNA polymerase, subunit A'' 16 382 1.5E-150 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_04155 94afda531df6241694b221ae2e4cc386 888 SUPERFAMILY SSF52374 3 579 2.29E-126 T 23-10-2018 A3L01_04155 94afda531df6241694b221ae2e4cc386 888 Gene3D G3DSA:3.40.50.620 22 535 2.0E-241 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_04155 94afda531df6241694b221ae2e4cc386 888 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_04155 94afda531df6241694b221ae2e4cc386 888 Gene3D G3DSA:1.10.730.10 2 750 2.0E-241 T 23-10-2018 A3L01_04155 94afda531df6241694b221ae2e4cc386 888 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 2.5E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L01_04155 94afda531df6241694b221ae2e4cc386 888 PRINTS PR00986 Valyl-tRNA synthetase signature 225 242 2.5E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L01_04155 94afda531df6241694b221ae2e4cc386 888 PRINTS PR00986 Valyl-tRNA synthetase signature 486 504 2.5E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L01_04155 94afda531df6241694b221ae2e4cc386 888 PRINTS PR00986 Valyl-tRNA synthetase signature 343 356 2.5E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L01_04155 94afda531df6241694b221ae2e4cc386 888 PRINTS PR00986 Valyl-tRNA synthetase signature 448 469 2.5E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L01_04155 94afda531df6241694b221ae2e4cc386 888 SUPERFAMILY SSF47323 586 824 1.51E-61 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_04155 94afda531df6241694b221ae2e4cc386 888 Hamap MF_02005 Valine--tRNA ligase [valS]. 2 793 28.895 T 23-10-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 A3L01_04155 94afda531df6241694b221ae2e4cc386 888 SUPERFAMILY SSF50677 187 335 9.16E-51 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L01_04155 94afda531df6241694b221ae2e4cc386 888 TIGRFAM TIGR00422 valS: valine--tRNA ligase 3 864 4.5E-271 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L01_04155 94afda531df6241694b221ae2e4cc386 888 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 570 3.5E-139 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_04155 94afda531df6241694b221ae2e4cc386 888 Gene3D G3DSA:3.90.740.10 170 337 2.0E-241 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L01_04155 94afda531df6241694b221ae2e4cc386 888 Pfam PF08264 Anticodon-binding domain of tRNA 614 762 2.9E-39 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A3L01_02815 a1e6d865fbc08620171f76da1deff7ff 439 Pfam PF00999 Sodium/hydrogen exchanger family 9 404 2.0E-44 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L01_02815 a1e6d865fbc08620171f76da1deff7ff 439 Gene3D G3DSA:1.20.1530.20 5 415 4.5E-66 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L01_04935 03c4129d6241152b3e3baea380fd5c0b 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 66 7.5E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_04935 03c4129d6241152b3e3baea380fd5c0b 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 68 83 7.5E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_04935 03c4129d6241152b3e3baea380fd5c0b 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 83 98 7.5E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_04935 03c4129d6241152b3e3baea380fd5c0b 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 35 50 7.5E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_04935 03c4129d6241152b3e3baea380fd5c0b 118 SMART SM00418 33 112 7.9E-33 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_04935 03c4129d6241152b3e3baea380fd5c0b 118 Gene3D G3DSA:1.10.10.10 1 118 2.9E-35 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_04935 03c4129d6241152b3e3baea380fd5c0b 118 SUPERFAMILY SSF46785 22 114 1.77E-28 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_04935 03c4129d6241152b3e3baea380fd5c0b 118 Pfam PF01022 Bacterial regulatory protein, arsR family 40 85 1.4E-16 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_04935 03c4129d6241152b3e3baea380fd5c0b 118 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 57 75 - T 23-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 A3L01_02165 57878033181cee0556a51b68fd33f123 339 Hamap MF_00280 50S ribosomal protein L10 [rpl10]. 1 283 35.802 T 23-10-2018 IPR022909 50S ribosomal protein L10, archaea A3L01_02165 57878033181cee0556a51b68fd33f123 339 Pfam PF00466 Ribosomal protein L10 5 105 6.7E-21 T 23-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 A3L01_02165 57878033181cee0556a51b68fd33f123 339 SUPERFAMILY SSF160369 5 141 1.96E-23 T 23-10-2018 A3L01_02165 57878033181cee0556a51b68fd33f123 339 Gene3D G3DSA:3.90.105.20 107 186 1.2E-73 T 23-10-2018 A3L01_02165 57878033181cee0556a51b68fd33f123 339 Gene3D G3DSA:3.30.70.1730 15 210 1.2E-73 T 23-10-2018 A3L01_00720 0e345ccc4ee9e7cfc1c00c3b32d6b383 151 SMART SM00670 3 133 1.1E-13 T 23-10-2018 IPR002716 PIN domain A3L01_00720 0e345ccc4ee9e7cfc1c00c3b32d6b383 151 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 5 141 9.467 T 23-10-2018 IPR022907 VapC family GO:0004540 A3L01_00720 0e345ccc4ee9e7cfc1c00c3b32d6b383 151 Pfam PF01850 PIN domain 5 135 5.1E-21 T 23-10-2018 IPR002716 PIN domain A3L01_00720 0e345ccc4ee9e7cfc1c00c3b32d6b383 151 SUPERFAMILY SSF88723 1 133 5.33E-20 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L01_00720 0e345ccc4ee9e7cfc1c00c3b32d6b383 151 Gene3D G3DSA:3.40.50.1010 4 138 3.9E-15 T 23-10-2018 A3L01_05780 0f858dd565e58ba704ea198948a01ae4 192 SUPERFAMILY SSF116726 103 183 4.45E-18 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L01_05780 0f858dd565e58ba704ea198948a01ae4 192 Pfam PF01895 PhoU domain 11 94 1.7E-8 T 23-10-2018 IPR026022 PhoU domain A3L01_05780 0f858dd565e58ba704ea198948a01ae4 192 Gene3D G3DSA:1.20.58.220 1 110 3.9E-19 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L01_05780 0f858dd565e58ba704ea198948a01ae4 192 SUPERFAMILY SSF109755 3 98 7.72E-15 T 23-10-2018 A3L01_05780 0f858dd565e58ba704ea198948a01ae4 192 Gene3D G3DSA:3.30.70.1450 111 190 1.5E-19 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L01_05780 0f858dd565e58ba704ea198948a01ae4 192 Pfam PF02080 TrkA-C domain 118 176 2.6E-14 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A3L01_08370 62a19b44fd18390c8e60582d80208639 280 Gene3D G3DSA:3.90.226.10 62 271 2.0E-23 T 23-10-2018 A3L01_08370 62a19b44fd18390c8e60582d80208639 280 SUPERFAMILY SSF52096 14 241 1.05E-28 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L01_08370 62a19b44fd18390c8e60582d80208639 280 Pfam PF01972 Serine dehydrogenase proteinase 9 276 3.1E-148 T 23-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 A3L01_05435 99e4c124671645afad6215c688859180 421 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 345 419 3.0E-13 T 23-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A3L01_05435 99e4c124671645afad6215c688859180 421 Gene3D G3DSA:3.40.50.150 75 414 2.9E-90 T 23-10-2018 A3L01_05435 99e4c124671645afad6215c688859180 421 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 402 412 - T 23-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site A3L01_05435 99e4c124671645afad6215c688859180 421 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 11 412 7.7E-67 T 23-10-2018 A3L01_05435 99e4c124671645afad6215c688859180 421 Gene3D G3DSA:3.40.1350.30 114 262 2.9E-90 T 23-10-2018 A3L01_05435 99e4c124671645afad6215c688859180 421 SUPERFAMILY SSF50249 3 59 1.54E-8 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_05435 99e4c124671645afad6215c688859180 421 Gene3D G3DSA:2.40.50.140 1 73 5.0E-15 T 23-10-2018 A3L01_05435 99e4c124671645afad6215c688859180 421 SUPERFAMILY SSF53335 62 419 6.98E-64 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_05435 99e4c124671645afad6215c688859180 421 Pfam PF02475 Met-10+ like-protein 277 334 8.0E-8 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 Gene3D G3DSA:2.170.16.10 541 598 2.4E-13 T 23-10-2018 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 SUPERFAMILY SSF55608 272 360 1.02E-15 T 23-10-2018 IPR027434 Homing endonuclease A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 SMART SM00306 58 169 2.8E-26 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 PRINTS PR00379 Intein signature 274 286 3.6E-15 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 PRINTS PR00379 Intein signature 180 192 3.6E-15 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 PRINTS PR00379 Intein signature 574 591 3.6E-15 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 PRINTS PR00379 Intein signature 131 144 3.6E-15 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 577 600 3.4E-6 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 Gene3D G3DSA:2.170.16.10 68 179 7.3E-21 T 23-10-2018 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 Pfam PF14890 Intein splicing domain 67 599 2.3E-27 T 23-10-2018 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 15 127 4.3E-7 T 23-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 SUPERFAMILY SSF47413 440 483 4.38E-7 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 Gene3D G3DSA:3.10.28.10 180 343 4.9E-27 T 23-10-2018 IPR027434 Homing endonuclease A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 Pfam PF14528 LAGLIDADG-like domain 273 346 5.6E-15 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 Pfam PF14528 LAGLIDADG-like domain 185 249 6.8E-6 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 SUPERFAMILY SSF52540 600 757 1.21E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 Pfam PF01381 Helix-turn-helix 440 482 9.4E-8 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 SMART SM00305 557 605 1.0E-10 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 Pfam PF13177 DNA polymerase III, delta subunit 629 709 1.1E-10 T 23-10-2018 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 Gene3D G3DSA:3.40.50.300 13 67 3.2E-16 T 23-10-2018 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 60 144 4.9E-17 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 Gene3D G3DSA:1.10.8.60 710 773 3.0E-25 T 23-10-2018 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 Gene3D G3DSA:3.40.50.300 599 709 1.7E-35 T 23-10-2018 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 Pfam PF08542 Replication factor C C-terminal domain 775 860 3.9E-22 T 23-10-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 Gene3D G3DSA:1.20.272.10 774 866 1.2E-36 T 23-10-2018 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 SMART SM00530 435 483 3.1E-7 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 Gene3D G3DSA:1.10.260.40 439 489 1.0E-6 T 23-10-2018 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 SUPERFAMILY SSF52540 12 61 3.44E-13 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 SUPERFAMILY SSF51294 59 599 8.63E-43 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L01_07805 92fe74eb199421f316f49466b56d0b1f 866 SUPERFAMILY SSF48019 775 864 1.84E-23 T 23-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A3L01_04560 5bb6ab524902d1b3863fa822c8d1fc3e 428 SUPERFAMILY SSF50465 321 424 4.68E-40 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A3L01_04560 5bb6ab524902d1b3863fa822c8d1fc3e 428 SUPERFAMILY SSF50447 213 315 7.9E-29 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L01_04560 5bb6ab524902d1b3863fa822c8d1fc3e 428 Gene3D G3DSA:2.40.30.10 320 425 5.9E-42 T 23-10-2018 A3L01_04560 5bb6ab524902d1b3863fa822c8d1fc3e 428 Gene3D G3DSA:2.40.30.10 216 310 3.2E-41 T 23-10-2018 A3L01_04560 5bb6ab524902d1b3863fa822c8d1fc3e 428 PRINTS PR00315 GTP-binding elongation factor signature 66 74 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_04560 5bb6ab524902d1b3863fa822c8d1fc3e 428 PRINTS PR00315 GTP-binding elongation factor signature 102 113 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_04560 5bb6ab524902d1b3863fa822c8d1fc3e 428 PRINTS PR00315 GTP-binding elongation factor signature 86 96 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_04560 5bb6ab524902d1b3863fa822c8d1fc3e 428 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_04560 5bb6ab524902d1b3863fa822c8d1fc3e 428 PRINTS PR00315 GTP-binding elongation factor signature 139 148 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_04560 5bb6ab524902d1b3863fa822c8d1fc3e 428 Pfam PF03144 Elongation factor Tu domain 2 235 306 7.7E-18 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A3L01_04560 5bb6ab524902d1b3863fa822c8d1fc3e 428 TIGRFAM TIGR00483 EF-1_alpha: translation elongation factor EF-1, subunit alpha 1 427 8.5E-215 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 A3L01_04560 5bb6ab524902d1b3863fa822c8d1fc3e 428 Gene3D G3DSA:3.40.50.300 1 212 3.3E-87 T 23-10-2018 A3L01_04560 5bb6ab524902d1b3863fa822c8d1fc3e 428 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 59 74 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site A3L01_04560 5bb6ab524902d1b3863fa822c8d1fc3e 428 Hamap MF_00118_A Elongation factor Tu [tuf]. 2 427 61.485 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 A3L01_04560 5bb6ab524902d1b3863fa822c8d1fc3e 428 SUPERFAMILY SSF52540 3 236 1.11E-76 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_04560 5bb6ab524902d1b3863fa822c8d1fc3e 428 Pfam PF00009 Elongation factor Tu GTP binding domain 5 209 1.0E-58 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_04560 5bb6ab524902d1b3863fa822c8d1fc3e 428 Pfam PF03143 Elongation factor Tu C-terminal domain 317 424 7.4E-38 T 23-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal A3L01_04560 5bb6ab524902d1b3863fa822c8d1fc3e 428 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 190 4.5E-17 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L01_04850 60463b2db3352ccef179bc9bd173109b 136 PIRSF PIRSF014543 1 123 6.7E-40 T 23-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 A3L01_04850 60463b2db3352ccef179bc9bd173109b 136 Pfam PF12646 Domain of unknown function (DUF3783) 58 113 2.9E-15 T 23-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 A3L01_07060 638d3fbfc7d7c681e2df19d841945445 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 441 448 1.9E-16 T 23-10-2018 A3L01_07060 638d3fbfc7d7c681e2df19d841945445 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 181 1.9E-16 T 23-10-2018 A3L01_07060 638d3fbfc7d7c681e2df19d841945445 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 323 1.9E-16 T 23-10-2018 A3L01_07060 638d3fbfc7d7c681e2df19d841945445 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 415 1.9E-16 T 23-10-2018 A3L01_07060 638d3fbfc7d7c681e2df19d841945445 482 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 18 472 3.7E-205 T 23-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 A3L01_07060 638d3fbfc7d7c681e2df19d841945445 482 Gene3D G3DSA:3.50.50.60 294 481 3.2E-29 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_07060 638d3fbfc7d7c681e2df19d841945445 482 Gene3D G3DSA:3.50.50.60 154 283 9.6E-37 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_07060 638d3fbfc7d7c681e2df19d841945445 482 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 22 140 1.3E-38 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A3L01_07060 638d3fbfc7d7c681e2df19d841945445 482 Gene3D G3DSA:1.10.1060.10 3 151 2.8E-39 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L01_07060 638d3fbfc7d7c681e2df19d841945445 482 SUPERFAMILY SSF46548 7 168 1.05E-31 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L01_07060 638d3fbfc7d7c681e2df19d841945445 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 426 448 1.9E-23 T 23-10-2018 A3L01_07060 638d3fbfc7d7c681e2df19d841945445 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 298 316 1.9E-23 T 23-10-2018 A3L01_07060 638d3fbfc7d7c681e2df19d841945445 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 400 416 1.9E-23 T 23-10-2018 A3L01_07060 638d3fbfc7d7c681e2df19d841945445 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 179 1.9E-23 T 23-10-2018 A3L01_07060 638d3fbfc7d7c681e2df19d841945445 482 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 159 457 4.2E-39 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L01_07060 638d3fbfc7d7c681e2df19d841945445 482 SUPERFAMILY SSF51971 157 408 6.47E-70 T 23-10-2018 A3L01_05130 7ebd16d616d40d25a5890d9a0006219d 330 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 183 197 1.0E-7 T 23-10-2018 A3L01_05130 7ebd16d616d40d25a5890d9a0006219d 330 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 247 259 1.0E-7 T 23-10-2018 A3L01_05130 7ebd16d616d40d25a5890d9a0006219d 330 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 269 293 1.0E-7 T 23-10-2018 A3L01_05130 7ebd16d616d40d25a5890d9a0006219d 330 Pfam PF01170 Putative RNA methylase family UPF0020 156 297 7.2E-25 T 23-10-2018 IPR000241 Putative RNA methylase domain A3L01_05130 7ebd16d616d40d25a5890d9a0006219d 330 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 250 256 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A3L01_05130 7ebd16d616d40d25a5890d9a0006219d 330 Gene3D G3DSA:3.30.2130.30 8 142 3.5E-5 T 23-10-2018 A3L01_05130 7ebd16d616d40d25a5890d9a0006219d 330 SMART SM00981 56 141 8.1E-7 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L01_05130 7ebd16d616d40d25a5890d9a0006219d 330 TIGRFAM TIGR01177 TIGR01177: putative methyltransferase, TIGR01177 family 3 327 3.6E-99 T 23-10-2018 IPR005885 tRNA guanine(10)-N2-dimethyltransferase GO:0004809|GO:0030488 A3L01_05130 7ebd16d616d40d25a5890d9a0006219d 330 SUPERFAMILY SSF143437 34 132 9.77E-9 T 23-10-2018 A3L01_05130 7ebd16d616d40d25a5890d9a0006219d 330 SUPERFAMILY SSF53335 156 298 1.37E-27 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_05130 7ebd16d616d40d25a5890d9a0006219d 330 Pfam PF02926 THUMP domain 48 133 7.0E-11 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L01_05130 7ebd16d616d40d25a5890d9a0006219d 330 Gene3D G3DSA:3.40.50.150 153 330 2.5E-31 T 23-10-2018 A3L01_04060 13e844d1de676b80751064e6a31d830c 177 Gene3D G3DSA:3.40.50.1950 1 177 1.7E-75 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A3L01_04060 13e844d1de676b80751064e6a31d830c 177 SUPERFAMILY SSF52507 1 176 3.4E-60 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A3L01_04060 13e844d1de676b80751064e6a31d830c 177 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 2 175 1.4E-73 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like A3L01_04060 13e844d1de676b80751064e6a31d830c 177 Pfam PF02441 Flavoprotein 1 156 3.3E-30 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A3L01_04060 13e844d1de676b80751064e6a31d830c 177 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 177 37.96 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like A3L01_02175 7a691fcb814bf7912e8ac3d453cacc26 163 SUPERFAMILY SSF46906 66 138 6.67E-23 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily A3L01_02175 7a691fcb814bf7912e8ac3d453cacc26 163 ProSitePatterns PS00359 Ribosomal protein L11 signature. 124 139 - T 23-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_02175 7a691fcb814bf7912e8ac3d453cacc26 163 Gene3D G3DSA:2.10.260.30 1 69 1.7E-28 T 23-10-2018 A3L01_02175 7a691fcb814bf7912e8ac3d453cacc26 163 Pfam PF00298 Ribosomal protein L11, RNA binding domain 70 137 8.9E-23 T 23-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A3L01_02175 7a691fcb814bf7912e8ac3d453cacc26 163 Gene3D G3DSA:1.10.10.250 73 163 1.2E-35 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily A3L01_02175 7a691fcb814bf7912e8ac3d453cacc26 163 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 1 139 28.66 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A3L01_02175 7a691fcb814bf7912e8ac3d453cacc26 163 SMART SM00649 5 138 4.9E-65 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A3L01_02175 7a691fcb814bf7912e8ac3d453cacc26 163 SUPERFAMILY SSF54747 3 82 2.75E-26 T 23-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily A3L01_02175 7a691fcb814bf7912e8ac3d453cacc26 163 Pfam PF03946 Ribosomal protein L11, N-terminal domain 5 58 6.0E-23 T 23-10-2018 IPR020784 Ribosomal protein L11, N-terminal A3L01_09430 2ac2e4c62dcebed957d11ad0c045babf 311 SUPERFAMILY SSF64182 3 310 2.49E-29 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L01_09430 2ac2e4c62dcebed957d11ad0c045babf 311 Pfam PF02272 DHHA1 domain 192 310 5.6E-6 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L01_05445 80270454027ade7ee4c0897378e4e0f3 597 TIGRFAM TIGR00491 aIF-2: translation initiation factor aIF-2 3 594 2.2E-242 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 A3L01_05445 80270454027ade7ee4c0897378e4e0f3 597 PRINTS PR00315 GTP-binding elongation factor signature 8 21 1.6E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_05445 80270454027ade7ee4c0897378e4e0f3 597 PRINTS PR00315 GTP-binding elongation factor signature 126 135 1.6E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_05445 80270454027ade7ee4c0897378e4e0f3 597 PRINTS PR00315 GTP-binding elongation factor signature 74 84 1.6E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_05445 80270454027ade7ee4c0897378e4e0f3 597 PRINTS PR00315 GTP-binding elongation factor signature 90 101 1.6E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_05445 80270454027ade7ee4c0897378e4e0f3 597 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 156 1.7E-20 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L01_05445 80270454027ade7ee4c0897378e4e0f3 597 Pfam PF00009 Elongation factor Tu GTP binding domain 8 214 7.8E-33 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_05445 80270454027ade7ee4c0897378e4e0f3 597 Pfam PF14578 Elongation factor Tu domain 4 467 553 1.9E-29 T 23-10-2018 IPR029459 Elongation factor Tu-type domain A3L01_05445 80270454027ade7ee4c0897378e4e0f3 597 Pfam PF11987 Translation-initiation factor 2 351 446 2.9E-24 T 23-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 A3L01_05445 80270454027ade7ee4c0897378e4e0f3 597 Gene3D G3DSA:2.40.30.10 466 556 2.2E-30 T 23-10-2018 A3L01_05445 80270454027ade7ee4c0897378e4e0f3 597 SUPERFAMILY SSF52156 334 460 1.57E-34 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily A3L01_05445 80270454027ade7ee4c0897378e4e0f3 597 Gene3D G3DSA:3.40.50.300 1 227 4.3E-66 T 23-10-2018 A3L01_05445 80270454027ade7ee4c0897378e4e0f3 597 Hamap MF_00100_A Translation initiation factor IF-2 [infB]. 2 596 43.653 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 A3L01_05445 80270454027ade7ee4c0897378e4e0f3 597 Gene3D G3DSA:2.40.30.10 228 338 4.6E-41 T 23-10-2018 A3L01_05445 80270454027ade7ee4c0897378e4e0f3 597 Gene3D G3DSA:3.40.50.10050 349 457 1.3E-36 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily A3L01_05445 80270454027ade7ee4c0897378e4e0f3 597 SUPERFAMILY SSF50447 465 589 2.55E-24 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L01_05445 80270454027ade7ee4c0897378e4e0f3 597 Pfam PF03144 Elongation factor Tu domain 2 247 325 9.5E-14 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A3L01_05445 80270454027ade7ee4c0897378e4e0f3 597 SUPERFAMILY SSF52540 5 288 1.42E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_02775 6445808ee806d5de76d34e914f425d80 239 SUPERFAMILY SSF88713 3 230 2.75E-31 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L01_02775 6445808ee806d5de76d34e914f425d80 239 Pfam PF01522 Polysaccharide deacetylase 3 125 4.9E-18 T 23-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A3L01_02775 6445808ee806d5de76d34e914f425d80 239 Gene3D G3DSA:3.20.20.370 1 238 1.5E-37 T 23-10-2018 A3L01_06415 a8e59d651cb5cd0e4ae0fcef3ac99392 462 SUPERFAMILY SSF52980 337 395 5.9E-5 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L01_06415 a8e59d651cb5cd0e4ae0fcef3ac99392 462 SUPERFAMILY SSF52540 3 238 5.99E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06415 a8e59d651cb5cd0e4ae0fcef3ac99392 462 Pfam PF01637 ATPase domain predominantly from Archaea 5 201 5.1E-27 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L01_06415 a8e59d651cb5cd0e4ae0fcef3ac99392 462 Pfam PF09339 IclR helix-turn-helix domain 241 282 1.8E-7 T 23-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A3L01_06415 a8e59d651cb5cd0e4ae0fcef3ac99392 462 Gene3D G3DSA:1.10.10.10 235 316 1.7E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_06415 a8e59d651cb5cd0e4ae0fcef3ac99392 462 SUPERFAMILY SSF46785 234 348 8.97E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_06415 a8e59d651cb5cd0e4ae0fcef3ac99392 462 Pfam PF03008 Archaea bacterial proteins of unknown function 306 403 4.5E-29 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L01_06415 a8e59d651cb5cd0e4ae0fcef3ac99392 462 Gene3D G3DSA:3.40.50.300 2 169 2.8E-29 T 23-10-2018 A3L01_05040 f08c31b51dcffb54df1fc383f9e85f77 175 SUPERFAMILY SSF55729 14 169 6.08E-23 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L01_05040 f08c31b51dcffb54df1fc383f9e85f77 175 Gene3D G3DSA:3.40.630.30 1 144 1.8E-61 T 23-10-2018 A3L01_05040 f08c31b51dcffb54df1fc383f9e85f77 175 Gene3D G3DSA:3.30.1990.20 145 175 7.0E-9 T 23-10-2018 A3L01_05040 f08c31b51dcffb54df1fc383f9e85f77 175 Pfam PF00583 Acetyltransferase (GNAT) family 34 160 1.1E-14 T 23-10-2018 IPR000182 GNAT domain A3L01_04365 20c67b9bdb2c7f6687d4ed3b368bf095 312 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 39 306 2.6E-93 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L01_04365 20c67b9bdb2c7f6687d4ed3b368bf095 312 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 228 244 7.4E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_04365 20c67b9bdb2c7f6687d4ed3b368bf095 312 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 112 122 7.4E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_04365 20c67b9bdb2c7f6687d4ed3b368bf095 312 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 83 97 7.4E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_04365 20c67b9bdb2c7f6687d4ed3b368bf095 312 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 178 190 7.4E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_04365 20c67b9bdb2c7f6687d4ed3b368bf095 312 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 289 306 7.4E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_04365 20c67b9bdb2c7f6687d4ed3b368bf095 312 Pfam PF01189 16S rRNA methyltransferase RsmB/F 101 304 3.5E-53 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L01_04365 20c67b9bdb2c7f6687d4ed3b368bf095 312 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 13 97 3.3E-17 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L01_04365 20c67b9bdb2c7f6687d4ed3b368bf095 312 SUPERFAMILY SSF53335 21 306 9.43E-62 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_04365 20c67b9bdb2c7f6687d4ed3b368bf095 312 Gene3D G3DSA:3.40.50.150 101 312 6.0E-73 T 23-10-2018 A3L01_04365 20c67b9bdb2c7f6687d4ed3b368bf095 312 Gene3D G3DSA:3.30.70.3130 5 96 2.4E-17 T 23-10-2018 A3L01_04730 ce204ef869f12190960cbb6eb361fea0 153 Pfam PF00578 AhpC/TSA family 10 128 1.3E-33 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L01_04730 ce204ef869f12190960cbb6eb361fea0 153 SUPERFAMILY SSF52833 9 149 2.67E-44 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L01_04730 ce204ef869f12190960cbb6eb361fea0 153 Gene3D G3DSA:3.40.30.10 2 148 1.2E-44 T 23-10-2018 A3L01_04730 ce204ef869f12190960cbb6eb361fea0 153 PIRSF PIRSF000239 4 149 4.6E-25 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L01_02185 e7eec7c64c6c3ffd57c3f5fe7a9da3b0 61 TIGRFAM TIGR00327 secE_euk_arch: protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic 5 60 7.0E-19 T 23-10-2018 IPR008158 Protein translocase SEC61 complex, gamma subunit GO:0015031|GO:0015450|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L01_02185 e7eec7c64c6c3ffd57c3f5fe7a9da3b0 61 SUPERFAMILY SSF103456 3 58 1.11E-19 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L01_02185 e7eec7c64c6c3ffd57c3f5fe7a9da3b0 61 Hamap MF_00422 Protein translocase subunit SecE [secE]. 6 61 12.635 T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L01_02185 e7eec7c64c6c3ffd57c3f5fe7a9da3b0 61 Gene3D G3DSA:1.20.5.820 1 61 1.7E-23 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L01_02185 e7eec7c64c6c3ffd57c3f5fe7a9da3b0 61 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 11 39 - T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L01_08880 4ea58cb612fd215dde40f8be8c72fdc0 430 ProSitePatterns PS00164 Enolase signature. 337 350 - T 23-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_08880 4ea58cb612fd215dde40f8be8c72fdc0 430 SUPERFAMILY SSF51604 139 428 8.65E-125 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A3L01_08880 4ea58cb612fd215dde40f8be8c72fdc0 430 Gene3D G3DSA:3.30.390.10 2 128 4.7E-56 T 23-10-2018 IPR029017 Enolase-like, N-terminal A3L01_08880 4ea58cb612fd215dde40f8be8c72fdc0 430 SUPERFAMILY SSF54826 6 140 4.18E-57 T 23-10-2018 A3L01_08880 4ea58cb612fd215dde40f8be8c72fdc0 430 Hamap MF_00318 Enolase [eno]. 5 414 45.975 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_08880 4ea58cb612fd215dde40f8be8c72fdc0 430 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 7 426 1.7E-197 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_08880 4ea58cb612fd215dde40f8be8c72fdc0 430 Pfam PF03952 Enolase, N-terminal domain 7 135 1.1E-59 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_08880 4ea58cb612fd215dde40f8be8c72fdc0 430 PIRSF PIRSF001400 3 427 6.5E-195 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_08880 4ea58cb612fd215dde40f8be8c72fdc0 430 PRINTS PR00148 Enolase signature 162 175 6.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_08880 4ea58cb612fd215dde40f8be8c72fdc0 430 PRINTS PR00148 Enolase signature 108 124 6.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_08880 4ea58cb612fd215dde40f8be8c72fdc0 430 PRINTS PR00148 Enolase signature 337 351 6.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_08880 4ea58cb612fd215dde40f8be8c72fdc0 430 PRINTS PR00148 Enolase signature 39 53 6.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_08880 4ea58cb612fd215dde40f8be8c72fdc0 430 PRINTS PR00148 Enolase signature 314 325 6.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_08880 4ea58cb612fd215dde40f8be8c72fdc0 430 PRINTS PR00148 Enolase signature 366 383 6.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_08880 4ea58cb612fd215dde40f8be8c72fdc0 430 SMART SM01193 7 135 1.1E-94 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_08880 4ea58cb612fd215dde40f8be8c72fdc0 430 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 427 3.3E-129 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_08880 4ea58cb612fd215dde40f8be8c72fdc0 430 SMART SM01192 140 428 2.9E-206 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_08880 4ea58cb612fd215dde40f8be8c72fdc0 430 Gene3D G3DSA:3.20.20.120 129 428 4.6E-133 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A3L01_08340 4290efd299ef244f31f7de6cc12810bb 499 Pfam PF04324 BFD-like [2Fe-2S] binding domain 407 465 8.5E-10 T 23-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A3L01_08340 4290efd299ef244f31f7de6cc12810bb 499 SUPERFAMILY SSF51905 3 271 4.75E-52 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_08340 4290efd299ef244f31f7de6cc12810bb 499 Gene3D G3DSA:3.50.50.60 5 356 7.4E-111 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_08340 4290efd299ef244f31f7de6cc12810bb 499 Gene3D G3DSA:1.10.10.1100 394 474 8.3E-15 T 23-10-2018 A3L01_08340 4290efd299ef244f31f7de6cc12810bb 499 SUPERFAMILY SSF54373 223 321 1.7E-9 T 23-10-2018 A3L01_08340 4290efd299ef244f31f7de6cc12810bb 499 Pfam PF01266 FAD dependent oxidoreductase 5 359 1.0E-68 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A3L01_08340 4290efd299ef244f31f7de6cc12810bb 499 Gene3D G3DSA:3.30.9.10 90 322 7.4E-111 T 23-10-2018 A3L01_06070 d9c5236af9cd66419a2bff09e3e924c0 786 SMART SM00490 372 461 9.8E-25 T 23-10-2018 IPR001650 Helicase, C-terminal A3L01_06070 d9c5236af9cd66419a2bff09e3e924c0 786 SUPERFAMILY SSF52540 52 480 2.29E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06070 d9c5236af9cd66419a2bff09e3e924c0 786 Gene3D G3DSA:1.10.150.20 710 784 1.0E-22 T 23-10-2018 A3L01_06070 d9c5236af9cd66419a2bff09e3e924c0 786 Pfam PF00270 DEAD/DEAH box helicase 14 148 3.0E-19 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L01_06070 d9c5236af9cd66419a2bff09e3e924c0 786 Gene3D G3DSA:3.40.50.300 1 199 2.2E-73 T 23-10-2018 A3L01_06070 d9c5236af9cd66419a2bff09e3e924c0 786 Gene3D G3DSA:1.20.1320.20 212 338 2.1E-101 T 23-10-2018 A3L01_06070 d9c5236af9cd66419a2bff09e3e924c0 786 SMART SM00278 723 742 1600.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L01_06070 d9c5236af9cd66419a2bff09e3e924c0 786 SMART SM00278 755 774 0.026 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L01_06070 d9c5236af9cd66419a2bff09e3e924c0 786 SUPERFAMILY SSF52980 570 698 1.56E-37 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L01_06070 d9c5236af9cd66419a2bff09e3e924c0 786 Gene3D G3DSA:3.40.50.10130 568 709 2.0E-52 T 23-10-2018 A3L01_06070 d9c5236af9cd66419a2bff09e3e924c0 786 Pfam PF12826 Helix-hairpin-helix motif 727 777 1.6E-9 T 23-10-2018 A3L01_06070 d9c5236af9cd66419a2bff09e3e924c0 786 SUPERFAMILY SSF47781 710 779 2.19E-15 T 23-10-2018 IPR010994 RuvA domain 2-like A3L01_06070 d9c5236af9cd66419a2bff09e3e924c0 786 Pfam PF02732 ERCC4 domain 575 693 2.0E-28 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 A3L01_06070 d9c5236af9cd66419a2bff09e3e924c0 786 SMART SM00487 6 201 2.4E-30 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L01_06070 d9c5236af9cd66419a2bff09e3e924c0 786 Gene3D G3DSA:3.40.50.300 209 478 2.1E-101 T 23-10-2018 A3L01_06070 d9c5236af9cd66419a2bff09e3e924c0 786 Pfam PF00271 Helicase conserved C-terminal domain 344 460 5.9E-24 T 23-10-2018 IPR001650 Helicase, C-terminal A3L01_06070 d9c5236af9cd66419a2bff09e3e924c0 786 SMART SM00891 572 652 1.6E-31 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 A3L01_03425 a8098fe4141f545174eb951b6212a794 294 Gene3D G3DSA:2.10.240.10 251 287 9.5E-8 T 23-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily A3L01_03425 a8098fe4141f545174eb951b6212a794 294 Pfam PF00970 Oxidoreductase FAD-binding domain 36 113 1.1E-8 T 23-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A3L01_03425 a8098fe4141f545174eb951b6212a794 294 PRINTS PR00410 Phenol hydroxylase reductase family signature 218 226 1.4E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L01_03425 a8098fe4141f545174eb951b6212a794 294 PRINTS PR00410 Phenol hydroxylase reductase family signature 52 64 1.4E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L01_03425 a8098fe4141f545174eb951b6212a794 294 PRINTS PR00410 Phenol hydroxylase reductase family signature 126 145 1.4E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L01_03425 a8098fe4141f545174eb951b6212a794 294 Gene3D G3DSA:3.40.50.80 119 250 2.2E-22 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L01_03425 a8098fe4141f545174eb951b6212a794 294 Pfam PF00175 Oxidoreductase NAD-binding domain 127 231 5.5E-13 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A3L01_03425 a8098fe4141f545174eb951b6212a794 294 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 250 286 9.1E-13 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L01_03425 a8098fe4141f545174eb951b6212a794 294 Gene3D G3DSA:2.40.30.10 16 114 4.9E-20 T 23-10-2018 A3L01_03425 a8098fe4141f545174eb951b6212a794 294 SUPERFAMILY SSF52343 110 285 1.19E-31 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L01_03425 a8098fe4141f545174eb951b6212a794 294 SUPERFAMILY SSF63380 15 118 4.3E-24 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L01_03425 a8098fe4141f545174eb951b6212a794 294 PIRSF PIRSF006816 16 293 2.2E-83 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L01_10030 0739f127c0c091b626d8527b1840746b 423 Pfam PF00079 Serpin (serine protease inhibitor) 59 421 1.9E-115 T 23-10-2018 IPR023796 Serpin domain A3L01_10030 0739f127c0c091b626d8527b1840746b 423 SMART SM00093 65 421 6.4E-120 T 23-10-2018 IPR023796 Serpin domain A3L01_10030 0739f127c0c091b626d8527b1840746b 423 Gene3D G3DSA:3.30.497.10 63 365 3.3E-124 T 23-10-2018 A3L01_10030 0739f127c0c091b626d8527b1840746b 423 ProSitePatterns PS00284 Serpins signature. 394 404 - T 23-10-2018 IPR023795 Serpin, conserved site A3L01_10030 0739f127c0c091b626d8527b1840746b 423 SUPERFAMILY SSF56574 50 421 9.16E-121 T 23-10-2018 IPR036186 Serpin superfamily A3L01_10030 0739f127c0c091b626d8527b1840746b 423 Gene3D G3DSA:2.30.39.10 220 421 3.3E-124 T 23-10-2018 A3L01_05645 6fd960ff3d9dbe2edee7ead59c48ee4e 172 PIRSF PIRSF016661 1 171 5.2E-49 T 23-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A3L01_05645 6fd960ff3d9dbe2edee7ead59c48ee4e 172 Pfam PF02632 BioY family 26 167 4.6E-40 T 23-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A3L01_05645 6fd960ff3d9dbe2edee7ead59c48ee4e 172 Gene3D G3DSA:1.10.1760.20 1 171 4.6E-56 T 23-10-2018 A3L01_02705 31e7d03294510c357e02c4d2d010edee 629 SUPERFAMILY SSF55261 278 404 9.65E-46 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A3L01_02705 31e7d03294510c357e02c4d2d010edee 629 Gene3D G3DSA:3.30.1360.30 274 404 4.0E-53 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A3L01_02705 31e7d03294510c357e02c4d2d010edee 629 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 177 191 - T 23-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 A3L01_02705 31e7d03294510c357e02c4d2d010edee 629 Hamap MF_00588 Glutamyl-tRNA(Gln) amidotransferase subunit E [gatE]. 1 629 339.531 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 A3L01_02705 31e7d03294510c357e02c4d2d010edee 629 TIGRFAM TIGR00134 gatE_arch: glutamyl-tRNA(Gln) amidotransferase, subunit E 5 627 1.2E-240 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 A3L01_02705 31e7d03294510c357e02c4d2d010edee 629 Gene3D G3DSA:1.10.10.410 566 624 6.9E-13 T 23-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal A3L01_02705 31e7d03294510c357e02c4d2d010edee 629 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 282 406 2.0E-53 T 23-10-2018 A3L01_02705 31e7d03294510c357e02c4d2d010edee 629 Pfam PF02934 GatB/GatE catalytic domain 13 444 2.7E-66 T 23-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 A3L01_02705 31e7d03294510c357e02c4d2d010edee 629 Pfam PF02637 GatB domain 485 624 4.2E-28 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A3L01_02705 31e7d03294510c357e02c4d2d010edee 629 SMART SM00845 484 624 7.0E-37 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A3L01_02705 31e7d03294510c357e02c4d2d010edee 629 SUPERFAMILY SSF55931 4 453 9.16E-102 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A3L01_02705 31e7d03294510c357e02c4d2d010edee 629 SUPERFAMILY SSF89095 482 624 6.67E-29 T 23-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 A3L01_02705 31e7d03294510c357e02c4d2d010edee 629 Pfam PF02938 GAD domain 299 390 4.0E-17 T 23-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 A3L01_02705 31e7d03294510c357e02c4d2d010edee 629 Gene3D G3DSA:1.10.150.380 453 546 2.8E-25 T 23-10-2018 A3L01_08145 49adb69254e567945a609066a8535267 124 Gene3D G3DSA:3.40.50.1010 2 123 2.7E-16 T 23-10-2018 A3L01_08145 49adb69254e567945a609066a8535267 124 Pfam PF01850 PIN domain 3 119 1.5E-19 T 23-10-2018 IPR002716 PIN domain A3L01_08145 49adb69254e567945a609066a8535267 124 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 124 10.922 T 23-10-2018 IPR022907 VapC family GO:0004540 A3L01_08145 49adb69254e567945a609066a8535267 124 SUPERFAMILY SSF88723 2 122 3.36E-23 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L01_02520 01646978154b4072c844a38f41dd5cc8 295 SUPERFAMILY SSF46785 196 272 8.43E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_02520 01646978154b4072c844a38f41dd5cc8 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 53 66 2.6E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L01_02520 01646978154b4072c844a38f41dd5cc8 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 145 157 2.6E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L01_02520 01646978154b4072c844a38f41dd5cc8 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 177 189 2.6E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L01_02520 01646978154b4072c844a38f41dd5cc8 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 78 94 2.6E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L01_02520 01646978154b4072c844a38f41dd5cc8 295 Pfam PF00557 Metallopeptidase family M24 7 287 8.4E-44 T 23-10-2018 IPR000994 Peptidase M24 A3L01_02520 01646978154b4072c844a38f41dd5cc8 295 Gene3D G3DSA:1.10.10.10 196 272 2.0E-106 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_02520 01646978154b4072c844a38f41dd5cc8 295 SUPERFAMILY SSF55920 3 295 3.53E-67 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like A3L01_02520 01646978154b4072c844a38f41dd5cc8 295 TIGRFAM TIGR00501 met_pdase_II: methionine aminopeptidase, type II 2 295 1.9E-118 T 23-10-2018 IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800|Reactome: R-HSA-2514859 A3L01_02520 01646978154b4072c844a38f41dd5cc8 295 Hamap MF_01975 Methionine aminopeptidase [map]. 4 295 47.719 T 23-10-2018 IPR028595 Methionine aminopeptidase, archaeal GO:0004177|GO:0006508 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L01_02520 01646978154b4072c844a38f41dd5cc8 295 ProSitePatterns PS01202 Methionine aminopeptidase subfamily 2 signature. 78 94 - T 23-10-2018 IPR018349 Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L01_02520 01646978154b4072c844a38f41dd5cc8 295 Gene3D G3DSA:3.90.230.10 9 286 2.0E-106 T 23-10-2018 A3L01_00410 bb0c94b30d0cf488cc0d8df6aa7c251e 317 Gene3D G3DSA:1.25.10.10 1 254 4.6E-78 T 23-10-2018 IPR011989 Armadillo-like helical A3L01_00410 bb0c94b30d0cf488cc0d8df6aa7c251e 317 SUPERFAMILY SSF48371 25 232 4.68E-15 T 23-10-2018 IPR016024 Armadillo-type fold A3L01_04010 6f5862f5a4229e66a4f9963ad51427df 348 SUPERFAMILY SSF55920 123 347 1.31E-85 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like A3L01_04010 6f5862f5a4229e66a4f9963ad51427df 348 Pfam PF00557 Metallopeptidase family M24 132 334 4.8E-71 T 23-10-2018 IPR000994 Peptidase M24 A3L01_04010 6f5862f5a4229e66a4f9963ad51427df 348 PRINTS PR00599 Methionine aminopeptidase-1 signature 302 314 7.7E-5 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L01_04010 6f5862f5a4229e66a4f9963ad51427df 348 PRINTS PR00599 Methionine aminopeptidase-1 signature 204 220 7.7E-5 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L01_04010 6f5862f5a4229e66a4f9963ad51427df 348 SUPERFAMILY SSF53092 6 124 6.45E-24 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L01_04010 6f5862f5a4229e66a4f9963ad51427df 348 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 124 3.9E-21 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 A3L01_04010 6f5862f5a4229e66a4f9963ad51427df 348 Gene3D G3DSA:3.90.230.10 123 348 1.6E-90 T 23-10-2018 A3L01_04010 6f5862f5a4229e66a4f9963ad51427df 348 Gene3D G3DSA:3.40.350.10 1 122 4.9E-28 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L01_04010 6f5862f5a4229e66a4f9963ad51427df 348 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 280 292 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site A3L01_01660 2383e6418af9fb6f894c84433a3ba178 399 Gene3D G3DSA:3.90.1150.10 16 387 1.6E-145 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L01_01660 2383e6418af9fb6f894c84433a3ba178 399 SUPERFAMILY SSF53383 5 397 4.95E-119 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L01_01660 2383e6418af9fb6f894c84433a3ba178 399 Pfam PF00266 Aminotransferase class-V 18 386 1.1E-138 T 23-10-2018 IPR000192 Aminotransferase class V domain A3L01_01660 2383e6418af9fb6f894c84433a3ba178 399 Gene3D G3DSA:3.40.640.10 36 292 1.6E-145 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L01_01660 2383e6418af9fb6f894c84433a3ba178 399 PIRSF PIRSF005572 15 399 9.4E-51 T 23-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 A3L01_04405 593ba81cc868dbfd97455350d163b7cf 148 Gene3D G3DSA:3.40.50.1000 7 143 7.3E-9 T 23-10-2018 IPR023214 HAD superfamily A3L01_04405 593ba81cc868dbfd97455350d163b7cf 148 SUPERFAMILY SSF56784 12 129 2.84E-10 T 23-10-2018 IPR036412 HAD-like superfamily A3L01_07480 5561b555d4264c98a57b69cc0a91b110 332 Gene3D G3DSA:3.40.50.1100 14 317 2.8E-115 T 23-10-2018 A3L01_07480 5561b555d4264c98a57b69cc0a91b110 332 Gene3D G3DSA:3.40.50.1100 53 156 2.8E-115 T 23-10-2018 A3L01_07480 5561b555d4264c98a57b69cc0a91b110 332 SUPERFAMILY SSF53686 10 321 6.17E-74 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L01_07480 5561b555d4264c98a57b69cc0a91b110 332 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 18 313 1.2E-40 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L01_07480 5561b555d4264c98a57b69cc0a91b110 332 TIGRFAM TIGR01275 ACC_deam_rel: pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family 15 325 2.8E-112 T 23-10-2018 IPR005966 D-cysteine desulfhydrase GO:0003824 KEGG: 00270+4.4.1.15 A3L01_07480 5561b555d4264c98a57b69cc0a91b110 332 PIRSF PIRSF006278 4 332 4.9E-86 T 23-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 SMART SM00889 506 619 4.3E-20 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 Hamap MF_00054_A Elongation factor G [fusA]. 2 725 43.824 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 SUPERFAMILY SSF50447 259 375 2.95E-33 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 Gene3D G3DSA:3.40.50.300 7 222 1.4E-73 T 23-10-2018 A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 Gene3D G3DSA:3.30.70.240 466 718 2.9E-75 T 23-10-2018 A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 Pfam PF03144 Elongation factor Tu domain 2 306 372 1.0E-14 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 153 2.7E-20 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 Pfam PF00679 Elongation factor G C-terminus 621 707 2.1E-24 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 Gene3D G3DSA:2.40.30.10 259 386 3.1E-27 T 23-10-2018 A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 Pfam PF14492 Elongation Factor G, domain II 387 459 5.8E-26 T 23-10-2018 A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 Pfam PF00009 Elongation factor Tu GTP binding domain 20 257 2.2E-64 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 SUPERFAMILY SSF54980 624 718 2.88E-24 T 23-10-2018 IPR035647 EF-G domain III/V-like A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 PRINTS PR00315 GTP-binding elongation factor signature 143 152 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 PRINTS PR00315 GTP-binding elongation factor signature 67 75 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 PRINTS PR00315 GTP-binding elongation factor signature 107 118 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 PRINTS PR00315 GTP-binding elongation factor signature 23 36 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 PRINTS PR00315 GTP-binding elongation factor signature 91 101 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 Gene3D G3DSA:3.30.230.10 472 720 2.9E-75 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 SUPERFAMILY SSF54980 388 463 4.32E-22 T 23-10-2018 IPR035647 EF-G domain III/V-like A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 SMART SM00838 621 708 1.0E-45 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 Gene3D G3DSA:3.30.70.870 388 465 4.9E-27 T 23-10-2018 A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 Pfam PF03764 Elongation factor G, domain IV 513 619 6.3E-27 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 SUPERFAMILY SSF52540 10 261 2.2E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 TIGRFAM TIGR00490 aEF-2: translation elongation factor aEF-2 3 720 0.0 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 A3L01_04570 1d7c731a5ad685f2ef5e36b4cd1c9a65 732 SUPERFAMILY SSF54211 463 623 6.57E-48 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L01_09785 b105f485527573cc5262eab8865d39f4 248 Hamap MF_01076 UPF0273 protein . 2 248 63.36 T 23-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like A3L01_09785 b105f485527573cc5262eab8865d39f4 248 Pfam PF06745 KaiC 5 237 6.9E-92 T 23-10-2018 IPR014774 KaiC-like domain A3L01_09785 b105f485527573cc5262eab8865d39f4 248 TIGRFAM TIGR03877 thermo_KaiC_1: KaiC domain protein, Ph0284 family 2 239 2.4E-141 T 23-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like A3L01_09785 b105f485527573cc5262eab8865d39f4 248 SUPERFAMILY SSF52540 2 236 2.71E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_09785 b105f485527573cc5262eab8865d39f4 248 Gene3D G3DSA:3.40.50.300 1 247 1.4E-81 T 23-10-2018 A3L01_09785 b105f485527573cc5262eab8865d39f4 248 PRINTS PR01874 DNA repair protein radA signature 14 42 4.2E-9 T 23-10-2018 A3L01_09785 b105f485527573cc5262eab8865d39f4 248 PRINTS PR01874 DNA repair protein radA signature 56 73 4.2E-9 T 23-10-2018 A3L01_09785 b105f485527573cc5262eab8865d39f4 248 PRINTS PR01874 DNA repair protein radA signature 167 195 4.2E-9 T 23-10-2018 A3L01_07745 856091be7ea691ab8ddba4dfbfddbc4d 279 Gene3D G3DSA:3.40.50.2020 16 138 3.5E-83 T 23-10-2018 A3L01_07745 856091be7ea691ab8ddba4dfbfddbc4d 279 SMART SM01400 2 113 5.1E-36 T 23-10-2018 A3L01_07745 856091be7ea691ab8ddba4dfbfddbc4d 279 Pfam PF00156 Phosphoribosyl transferase domain 140 239 2.4E-18 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L01_07745 856091be7ea691ab8ddba4dfbfddbc4d 279 Hamap MF_00583_A Putative ribose-phosphate pyrophosphokinase [prs]. 1 278 36.375 T 23-10-2018 IPR037514 Ribose-phosphate pyrophosphokinase, archaea GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A3L01_07745 856091be7ea691ab8ddba4dfbfddbc4d 279 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 2 276 2.6E-91 T 23-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A3L01_07745 856091be7ea691ab8ddba4dfbfddbc4d 279 SUPERFAMILY SSF53271 80 264 7.26E-39 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L01_07745 856091be7ea691ab8ddba4dfbfddbc4d 279 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 5 110 7.2E-22 T 23-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A3L01_07745 856091be7ea691ab8ddba4dfbfddbc4d 279 Gene3D G3DSA:3.40.50.2020 139 263 3.5E-83 T 23-10-2018 A3L01_09740 37bea01d61087b3c0b9015dec47ed074 590 SUPERFAMILY SSF102114 84 380 4.32E-36 T 23-10-2018 A3L01_09740 37bea01d61087b3c0b9015dec47ed074 590 Gene3D G3DSA:3.80.30.20 231 381 3.0E-13 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L01_09740 37bea01d61087b3c0b9015dec47ed074 590 Pfam PF16199 Radical_SAM C-terminal domain 334 413 7.2E-27 T 23-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 A3L01_09740 37bea01d61087b3c0b9015dec47ed074 590 Pfam PF04055 Radical SAM superfamily 85 318 5.3E-30 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L01_09740 37bea01d61087b3c0b9015dec47ed074 590 SMART SM00729 78 373 1.9E-49 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L01_09740 37bea01d61087b3c0b9015dec47ed074 590 Gene3D G3DSA:3.40.630.30 421 571 1.5E-8 T 23-10-2018 A3L01_09740 37bea01d61087b3c0b9015dec47ed074 590 TIGRFAM TIGR01211 ELP3: radical SAM enzyme/protein acetyltransferase, ELP3 family 15 571 6.9E-265 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 A3L01_09740 37bea01d61087b3c0b9015dec47ed074 590 SUPERFAMILY SSF55729 446 567 2.09E-10 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L01_09740 37bea01d61087b3c0b9015dec47ed074 590 Pfam PF00583 Acetyltransferase (GNAT) family 458 560 4.2E-8 T 23-10-2018 IPR000182 GNAT domain A3L01_09740 37bea01d61087b3c0b9015dec47ed074 590 PIRSF PIRSF005669 1 572 2.0E-250 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 A3L01_06575 9e4b356e8f4a37dba56bd42fed3f5c56 344 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_06575 9e4b356e8f4a37dba56bd42fed3f5c56 344 Pfam PF00005 ABC transporter 16 159 6.5E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_06575 9e4b356e8f4a37dba56bd42fed3f5c56 344 SMART SM00382 25 234 1.7E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_06575 9e4b356e8f4a37dba56bd42fed3f5c56 344 Pfam PF03459 TOBE domain 281 343 5.9E-15 T 23-10-2018 IPR005116 Transport-associated OB, type 1 A3L01_06575 9e4b356e8f4a37dba56bd42fed3f5c56 344 Gene3D G3DSA:3.40.50.300 1 234 1.2E-71 T 23-10-2018 A3L01_06575 9e4b356e8f4a37dba56bd42fed3f5c56 344 Gene3D G3DSA:2.40.50.140 243 343 6.5E-26 T 23-10-2018 A3L01_06575 9e4b356e8f4a37dba56bd42fed3f5c56 344 SUPERFAMILY SSF52540 1 237 2.73E-79 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06575 9e4b356e8f4a37dba56bd42fed3f5c56 344 SUPERFAMILY SSF50331 235 344 1.39E-22 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L01_06575 9e4b356e8f4a37dba56bd42fed3f5c56 344 Gene3D G3DSA:2.40.50.100 268 339 6.5E-26 T 23-10-2018 A3L01_06575 9e4b356e8f4a37dba56bd42fed3f5c56 344 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 280 343 7.8E-17 T 23-10-2018 IPR004606 Molybdenum-pterin binding GO:0015689 A3L01_02480 d1c898bc92ec39b5a7a89c280aba8c44 577 SUPERFAMILY SSF51445 216 393 2.74E-5 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L01_02480 d1c898bc92ec39b5a7a89c280aba8c44 577 Pfam PF16317 Glycosyl hydrolase family 99 207 452 8.1E-30 T 23-10-2018 IPR026071 Glycosyl hydrolase family 99 GO:0016798 A3L01_02480 d1c898bc92ec39b5a7a89c280aba8c44 577 Gene3D G3DSA:3.20.20.80 180 478 1.6E-68 T 23-10-2018 A3L01_05345 b63bdca3b7d07d353ef9c07ce13c703c 180 Gene3D G3DSA:3.40.50.300 3 176 2.4E-41 T 23-10-2018 A3L01_05345 b63bdca3b7d07d353ef9c07ce13c703c 180 Hamap MF_00796 Nucleoside-triphosphatase . 3 175 30.199 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A3L01_05345 b63bdca3b7d07d353ef9c07ce13c703c 180 Pfam PF03266 NTPase 4 168 1.2E-54 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A3L01_05345 b63bdca3b7d07d353ef9c07ce13c703c 180 SMART SM00382 1 158 1.5E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_05345 b63bdca3b7d07d353ef9c07ce13c703c 180 SUPERFAMILY SSF52540 5 149 4.18E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_04015 1a5bac54c81e1f816ebc8fe25159436b 357 Gene3D G3DSA:2.30.30.870 1 130 1.1E-38 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain A3L01_04015 1a5bac54c81e1f816ebc8fe25159436b 357 Gene3D G3DSA:3.30.420.60 133 256 5.4E-35 T 23-10-2018 A3L01_04015 1a5bac54c81e1f816ebc8fe25159436b 357 Hamap MF_01853 Protein pelota homolog [pelA]. 2 356 37.191 T 23-10-2018 IPR023521 Translation release factor pelota, archaea GO:0070481|GO:0070966|GO:0071025 A3L01_04015 1a5bac54c81e1f816ebc8fe25159436b 357 TIGRFAM TIGR00111 pelota: mRNA surveillance protein pelota 1 356 1.5E-110 T 23-10-2018 IPR004405 Translation release factor pelota GO:0070481|GO:0070966|GO:0071025 A3L01_04015 1a5bac54c81e1f816ebc8fe25159436b 357 SMART SM01194 1 129 1.2E-47 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A3L01_04015 1a5bac54c81e1f816ebc8fe25159436b 357 Gene3D G3DSA:3.30.1330.30 258 357 7.5E-33 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L01_04015 1a5bac54c81e1f816ebc8fe25159436b 357 Pfam PF03465 eRF1 domain 3 261 356 2.6E-25 T 23-10-2018 IPR005142 eRF1 domain 3 A3L01_04015 1a5bac54c81e1f816ebc8fe25159436b 357 SUPERFAMILY SSF53137 131 259 4.27E-30 T 23-10-2018 A3L01_04015 1a5bac54c81e1f816ebc8fe25159436b 357 Pfam PF03463 eRF1 domain 1 6 127 3.1E-29 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A3L01_04015 1a5bac54c81e1f816ebc8fe25159436b 357 Pfam PF03464 eRF1 domain 2 136 248 2.2E-15 T 23-10-2018 IPR005141 eRF1 domain 2 A3L01_04015 1a5bac54c81e1f816ebc8fe25159436b 357 SUPERFAMILY SSF159065 2 129 1.27E-35 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain A3L01_04015 1a5bac54c81e1f816ebc8fe25159436b 357 SUPERFAMILY SSF55315 251 356 7.06E-29 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L01_02225 e42a8ffeb88c9dff42b5915516ca946d 194 Pfam PF08745 PINc domain ribonuclease 2 190 9.1E-67 T 23-10-2018 IPR014856 PIN-domain ribonuclease A3L01_02225 e42a8ffeb88c9dff42b5915516ca946d 194 Hamap MF_01078 UPF0278 protein . 1 193 30.365 T 23-10-2018 IPR014856 PIN-domain ribonuclease A3L01_02225 e42a8ffeb88c9dff42b5915516ca946d 194 SUPERFAMILY SSF88723 75 188 6.17E-8 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L01_02225 e42a8ffeb88c9dff42b5915516ca946d 194 TIGRFAM TIGR03875 RNA_lig_partner: RNA ligase partner, MJ_0950 family 2 189 1.4E-71 T 23-10-2018 IPR014856 PIN-domain ribonuclease A3L01_06590 888f0339250766d771e165fc7172b75c 460 Pfam PF01637 ATPase domain predominantly from Archaea 6 203 7.0E-19 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L01_06590 888f0339250766d771e165fc7172b75c 460 SUPERFAMILY SSF52540 4 242 1.13E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06590 888f0339250766d771e165fc7172b75c 460 Gene3D G3DSA:3.40.50.300 1 169 1.8E-25 T 23-10-2018 A3L01_06590 888f0339250766d771e165fc7172b75c 460 Pfam PF03008 Archaea bacterial proteins of unknown function 308 407 1.0E-32 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L01_06590 888f0339250766d771e165fc7172b75c 460 SUPERFAMILY SSF46785 240 318 8.44E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_06955 402bad2a83a0e0f9ed8fa9948a57f494 122 Pfam PF09946 Predicted membrane protein (DUF2178) 14 82 5.1E-8 T 23-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane A3L01_06705 cdfc37f69ef531a2da8ee40402ff998e 335 Gene3D G3DSA:3.40.50.720 3 308 1.0E-84 T 23-10-2018 A3L01_06705 cdfc37f69ef531a2da8ee40402ff998e 335 SUPERFAMILY SSF51735 3 142 1.77E-46 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_06705 cdfc37f69ef531a2da8ee40402ff998e 335 SUPERFAMILY SSF55347 154 303 2.29E-23 T 23-10-2018 A3L01_06705 cdfc37f69ef531a2da8ee40402ff998e 335 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 121 8.5E-29 T 23-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A3L01_06705 cdfc37f69ef531a2da8ee40402ff998e 335 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 156 235 3.9E-8 T 23-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 A3L01_06705 cdfc37f69ef531a2da8ee40402ff998e 335 Gene3D G3DSA:3.30.360.10 122 321 1.0E-84 T 23-10-2018 A3L01_01115 aa83251dbd85ed1ea7df82613b326dda 184 Pfam PF00347 Ribosomal protein L6 13 85 1.1E-17 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01115 aa83251dbd85ed1ea7df82613b326dda 184 Pfam PF00347 Ribosomal protein L6 97 171 1.3E-15 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01115 aa83251dbd85ed1ea7df82613b326dda 184 SUPERFAMILY SSF56053 86 177 4.1E-31 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01115 aa83251dbd85ed1ea7df82613b326dda 184 Gene3D G3DSA:3.90.930.12 6 85 2.0E-30 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01115 aa83251dbd85ed1ea7df82613b326dda 184 TIGRFAM TIGR03653 uL6_arch: ribosomal protein uL6 8 177 3.1E-79 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 A3L01_01115 aa83251dbd85ed1ea7df82613b326dda 184 Gene3D G3DSA:3.90.930.12 86 182 2.7E-38 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01115 aa83251dbd85ed1ea7df82613b326dda 184 Hamap MF_01365_A 50S ribosomal protein L6 [rplF]. 2 178 39.407 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 A3L01_01115 aa83251dbd85ed1ea7df82613b326dda 184 ProSitePatterns PS00700 Ribosomal protein L6 signature 2. 156 177 - T 23-10-2018 IPR002359 Ribosomal protein L6, conserved site-2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01115 aa83251dbd85ed1ea7df82613b326dda 184 PIRSF PIRSF002162 5 182 1.7E-39 T 23-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01115 aa83251dbd85ed1ea7df82613b326dda 184 SUPERFAMILY SSF56053 8 85 3.24E-22 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 Gene3D G3DSA:3.10.330.10 93 173 1.9E-7 T 23-10-2018 A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 Gene3D G3DSA:1.10.8.60 423 511 4.8E-15 T 23-10-2018 A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 Gene3D G3DSA:1.10.8.60 684 792 1.6E-34 T 23-10-2018 A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 SUPERFAMILY SSF50692 1 90 1.57E-30 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 7 793 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 SMART SM01073 8 92 9.4E-44 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 SMART SM01072 107 170 1.0E-17 T 23-10-2018 IPR004201 CDC48, domain 2 A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 Gene3D G3DSA:3.40.50.300 512 682 5.0E-75 T 23-10-2018 A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 108 169 2.6E-14 T 23-10-2018 IPR004201 CDC48, domain 2 A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 Gene3D G3DSA:2.40.40.20 1 92 7.2E-37 T 23-10-2018 A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 219 348 1.8E-51 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 553 682 1.8E-49 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 SUPERFAMILY SSF52540 511 790 5.94E-81 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 Gene3D G3DSA:3.40.50.300 179 349 1.9E-82 T 23-10-2018 A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 ProSitePatterns PS00674 AAA-protein family signature. 653 671 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 SUPERFAMILY SSF52540 179 501 3.52E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 Gene3D G3DSA:1.10.8.60 350 407 1.9E-82 T 23-10-2018 A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 8 91 2.7E-35 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 SUPERFAMILY SSF54585 92 184 1.96E-20 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 ProSitePatterns PS00674 AAA-protein family signature. 319 337 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 SMART SM00382 215 351 1.7E-25 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_06335 dc0847da13ee3db281c0945d309749ef 796 SMART SM00382 549 685 8.9E-25 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 169 668 5.2E-81 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 399 405 - T 23-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 SUPERFAMILY SSF55008 3 57 1.31E-9 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 Gene3D G3DSA:2.70.150.20 189 301 7.3E-35 T 23-10-2018 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 246 260 2.4E-22 T 23-10-2018 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 397 411 2.4E-22 T 23-10-2018 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 535 545 2.4E-22 T 23-10-2018 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 614 626 2.4E-22 T 23-10-2018 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 590 609 2.4E-22 T 23-10-2018 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 SUPERFAMILY SSF56784 395 691 3.8E-61 T 23-10-2018 IPR036412 HAD-like superfamily A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 Gene3D G3DSA:3.40.1110.10 408 519 5.9E-84 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 147 692 1.3E-180 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 PRINTS PR00941 Cadmium-transporting ATPase signature 262 278 6.9E-9 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 PRINTS PR00941 Cadmium-transporting ATPase signature 5 14 6.9E-9 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 PRINTS PR00941 Cadmium-transporting ATPase signature 109 126 6.9E-9 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 PRINTS PR00941 Cadmium-transporting ATPase signature 281 295 6.9E-9 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 PRINTS PR00941 Cadmium-transporting ATPase signature 181 201 6.9E-9 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 Gene3D G3DSA:3.40.50.1000 378 643 5.9E-84 T 23-10-2018 IPR023214 HAD superfamily A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 147 695 1.3E-168 T 23-10-2018 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 SUPERFAMILY SSF81665 147 690 1.57E-13 T 23-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 Pfam PF00702 haloacid dehalogenase-like hydrolase 395 604 1.2E-39 T 23-10-2018 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 Pfam PF00403 Heavy-metal-associated domain 6 57 4.5E-10 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 35 - T 23-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 Pfam PF00122 E1-E2 ATPase 197 377 6.3E-55 T 23-10-2018 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 Gene3D G3DSA:3.30.70.100 3 81 7.7E-10 T 23-10-2018 A3L01_04930 1369f2c007efcb33df814e1a5e1541be 695 SUPERFAMILY SSF81653 201 296 5.36E-26 T 23-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 A3L01_04285 fbf941f1c00f5f7d7a45421174d9ea39 274 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 214 235 2.3E-11 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L01_04285 fbf941f1c00f5f7d7a45421174d9ea39 274 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 57 67 2.3E-11 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L01_04285 fbf941f1c00f5f7d7a45421174d9ea39 274 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 154 2.3E-11 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L01_04285 fbf941f1c00f5f7d7a45421174d9ea39 274 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 2.3E-11 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L01_04285 fbf941f1c00f5f7d7a45421174d9ea39 274 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 36 51 2.3E-11 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L01_04285 fbf941f1c00f5f7d7a45421174d9ea39 274 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 134 152 3.6E-21 T 23-10-2018 A3L01_04285 fbf941f1c00f5f7d7a45421174d9ea39 274 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 212 228 3.6E-21 T 23-10-2018 A3L01_04285 fbf941f1c00f5f7d7a45421174d9ea39 274 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.6E-21 T 23-10-2018 A3L01_04285 fbf941f1c00f5f7d7a45421174d9ea39 274 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 3.6E-21 T 23-10-2018 A3L01_04285 fbf941f1c00f5f7d7a45421174d9ea39 274 Gene3D G3DSA:3.50.50.60 6 263 1.2E-43 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_04285 fbf941f1c00f5f7d7a45421174d9ea39 274 Gene3D G3DSA:3.50.50.60 113 220 1.2E-43 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_04285 fbf941f1c00f5f7d7a45421174d9ea39 274 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 236 9.8E-21 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L01_04285 fbf941f1c00f5f7d7a45421174d9ea39 274 SUPERFAMILY SSF51905 4 267 4.15E-34 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_07550 519312bb1f23852bef7af9f9580cfb8b 390 PIRSF PIRSF000484 68 386 1.6E-48 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A3L01_07550 519312bb1f23852bef7af9f9580cfb8b 390 PIRSF PIRSF000484 8 71 0.73 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A3L01_07550 519312bb1f23852bef7af9f9580cfb8b 390 Gene3D G3DSA:3.90.1170.20 1 106 7.4E-45 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 A3L01_07550 519312bb1f23852bef7af9f9580cfb8b 390 Gene3D G3DSA:3.20.140.10 300 387 6.1E-6 T 23-10-2018 A3L01_07550 519312bb1f23852bef7af9f9580cfb8b 390 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 115 303 1.3E-27 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 A3L01_07550 519312bb1f23852bef7af9f9580cfb8b 390 SUPERFAMILY SSF51690 112 385 6.18E-77 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A3L01_07550 519312bb1f23852bef7af9f9580cfb8b 390 SUPERFAMILY SSF54675 2 115 1.26E-32 T 23-10-2018 A3L01_07550 519312bb1f23852bef7af9f9580cfb8b 390 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 52 113 1.8E-6 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A3L01_07550 519312bb1f23852bef7af9f9580cfb8b 390 Gene3D G3DSA:3.20.20.70 107 297 2.1E-63 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_03810 878e1a6e84578b0ba0a4ea8234d48562 222 Gene3D G3DSA:1.10.150.240 17 86 1.6E-34 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A3L01_03810 878e1a6e84578b0ba0a4ea8234d48562 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 4.9E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_03810 878e1a6e84578b0ba0a4ea8234d48562 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 101 114 4.9E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_03810 878e1a6e84578b0ba0a4ea8234d48562 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 152 172 4.9E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_03810 878e1a6e84578b0ba0a4ea8234d48562 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 179 192 4.9E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_03810 878e1a6e84578b0ba0a4ea8234d48562 222 Gene3D G3DSA:3.40.50.1000 6 191 1.6E-34 T 23-10-2018 IPR023214 HAD superfamily A3L01_03810 878e1a6e84578b0ba0a4ea8234d48562 222 SUPERFAMILY SSF56784 1 217 6.17E-45 T 23-10-2018 IPR036412 HAD-like superfamily A3L01_03810 878e1a6e84578b0ba0a4ea8234d48562 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 189 6.0E-29 T 23-10-2018 A3L01_03810 878e1a6e84578b0ba0a4ea8234d48562 222 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 124 188 2.0E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_03810 878e1a6e84578b0ba0a4ea8234d48562 222 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 97 184 7.8E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_03685 6999f67aa28d01230c29c9037c5cdab5 301 SUPERFAMILY SSF52540 101 301 2.94E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_03685 6999f67aa28d01230c29c9037c5cdab5 301 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 25 298 5.2E-109 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A3L01_03685 6999f67aa28d01230c29c9037c5cdab5 301 SMART SM00962 104 299 5.9E-114 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L01_03685 6999f67aa28d01230c29c9037c5cdab5 301 Gene3D G3DSA:1.20.120.140 3 87 5.3E-22 T 23-10-2018 A3L01_03685 6999f67aa28d01230c29c9037c5cdab5 301 Pfam PF02881 SRP54-type protein, helical bundle domain 5 79 4.0E-14 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L01_03685 6999f67aa28d01230c29c9037c5cdab5 301 SMART SM00963 1 85 2.3E-16 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L01_03685 6999f67aa28d01230c29c9037c5cdab5 301 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 272 285 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L01_03685 6999f67aa28d01230c29c9037c5cdab5 301 SMART SM00382 103 298 1.1E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_03685 6999f67aa28d01230c29c9037c5cdab5 301 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 24 299 58.642 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A3L01_03685 6999f67aa28d01230c29c9037c5cdab5 301 SUPERFAMILY SSF47364 1 89 3.66E-17 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 A3L01_03685 6999f67aa28d01230c29c9037c5cdab5 301 Pfam PF00448 SRP54-type protein, GTPase domain 104 298 2.0E-80 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L01_03685 6999f67aa28d01230c29c9037c5cdab5 301 Gene3D G3DSA:3.40.50.300 90 298 3.0E-86 T 23-10-2018 A3L01_02070 88b1711cf2cf1fdfce2403919566fbb8 450 SUPERFAMILY SSF103473 24 443 1.44E-39 T 23-10-2018 IPR036259 MFS transporter superfamily A3L01_02070 88b1711cf2cf1fdfce2403919566fbb8 450 Gene3D G3DSA:1.20.1250.20 23 297 5.6E-17 T 23-10-2018 A3L01_02070 88b1711cf2cf1fdfce2403919566fbb8 450 Gene3D G3DSA:1.20.1250.20 298 448 1.5E-14 T 23-10-2018 A3L01_02070 88b1711cf2cf1fdfce2403919566fbb8 450 Pfam PF07690 Major Facilitator Superfamily 269 441 9.0E-12 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L01_05755 5e451adbe6dfbf417704b8c3d852ce8d 325 Gene3D G3DSA:3.40.50.300 1 237 1.3E-73 T 23-10-2018 A3L01_05755 5e451adbe6dfbf417704b8c3d852ce8d 325 Pfam PF13732 Domain of unknown function (DUF4162) 215 300 1.7E-8 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 A3L01_05755 5e451adbe6dfbf417704b8c3d852ce8d 325 SMART SM00382 28 210 3.9E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_05755 5e451adbe6dfbf417704b8c3d852ce8d 325 SUPERFAMILY SSF52540 3 222 2.19E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_05755 5e451adbe6dfbf417704b8c3d852ce8d 325 Pfam PF00005 ABC transporter 20 160 5.0E-34 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_05755 5e451adbe6dfbf417704b8c3d852ce8d 325 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 11 302 6.2E-120 T 23-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A3L01_05755 5e451adbe6dfbf417704b8c3d852ce8d 325 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_07590 080bc8dc1e06d9490ba46ec5a2c851ad 243 Gene3D G3DSA:1.10.260.40 24 80 7.9E-11 T 23-10-2018 A3L01_07590 080bc8dc1e06d9490ba46ec5a2c851ad 243 SUPERFAMILY SSF47413 22 75 4.1E-12 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L01_07590 080bc8dc1e06d9490ba46ec5a2c851ad 243 PIRSF PIRSF037724 1 237 2.7E-104 T 23-10-2018 IPR017271 Transcription regulator HTH, MJ1545, predicted A3L01_07590 080bc8dc1e06d9490ba46ec5a2c851ad 243 Pfam PF01381 Helix-turn-helix 28 75 4.0E-9 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L01_07590 080bc8dc1e06d9490ba46ec5a2c851ad 243 SMART SM00530 26 81 1.1E-12 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L01_04890 8541d9785f9bf6ed661e98aef1b0eaf5 636 SUPERFAMILY SSF53706 3 524 3.01E-138 T 23-10-2018 A3L01_04890 8541d9785f9bf6ed661e98aef1b0eaf5 636 SMART SM00926 1 53 2.6E-9 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_04890 8541d9785f9bf6ed661e98aef1b0eaf5 636 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 4 47 3.4E-7 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_04890 8541d9785f9bf6ed661e98aef1b0eaf5 636 Gene3D G3DSA:3.30.2070.10 407 487 2.0E-121 T 23-10-2018 A3L01_04890 8541d9785f9bf6ed661e98aef1b0eaf5 636 Pfam PF01568 Molydopterin dinucleotide binding domain 527 629 1.3E-21 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A3L01_04890 8541d9785f9bf6ed661e98aef1b0eaf5 636 Pfam PF00384 Molybdopterin oxidoreductase 56 421 2.6E-46 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_04890 8541d9785f9bf6ed661e98aef1b0eaf5 636 Gene3D G3DSA:2.20.25.90 2 58 3.1E-10 T 23-10-2018 A3L01_04890 8541d9785f9bf6ed661e98aef1b0eaf5 636 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 558 585 - T 23-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A3L01_04890 8541d9785f9bf6ed661e98aef1b0eaf5 636 Gene3D G3DSA:3.40.228.10 133 505 2.0E-121 T 23-10-2018 A3L01_04890 8541d9785f9bf6ed661e98aef1b0eaf5 636 Gene3D G3DSA:3.40.50.740 67 450 2.0E-121 T 23-10-2018 A3L01_04890 8541d9785f9bf6ed661e98aef1b0eaf5 636 SUPERFAMILY SSF50692 516 636 8.08E-34 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L01_04890 8541d9785f9bf6ed661e98aef1b0eaf5 636 Gene3D G3DSA:2.40.40.20 517 636 7.7E-32 T 23-10-2018 A3L01_06200 3cec9cbab81612ebf013de204640a24c 234 SUPERFAMILY SSF81301 20 74 5.82E-8 T 23-10-2018 A3L01_06200 3cec9cbab81612ebf013de204640a24c 234 Gene3D G3DSA:3.30.460.10 21 95 2.1E-6 T 23-10-2018 A3L01_06200 3cec9cbab81612ebf013de204640a24c 234 PIRSF PIRSF005928 10 232 2.2E-103 T 23-10-2018 IPR009185 Predicted nucleotidyltransferase A3L01_06200 3cec9cbab81612ebf013de204640a24c 234 Pfam PF01909 Nucleotidyltransferase domain 31 73 9.9E-7 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L01_06185 4c22ae8cae8819a1ea8a1da38fe42dc0 339 Gene3D G3DSA:3.40.50.11030 235 339 6.3E-39 T 23-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily A3L01_06185 4c22ae8cae8819a1ea8a1da38fe42dc0 339 Pfam PF01300 Telomere recombination 22 196 7.4E-61 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 A3L01_06185 4c22ae8cae8819a1ea8a1da38fe42dc0 339 Pfam PF03481 Putative GTP-binding controlling metal-binding 200 333 1.6E-27 T 23-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain A3L01_06185 4c22ae8cae8819a1ea8a1da38fe42dc0 339 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 12 207 4.2E-67 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 A3L01_06185 4c22ae8cae8819a1ea8a1da38fe42dc0 339 PIRSF PIRSF004930 1 338 3.0E-131 T 23-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 A3L01_06185 4c22ae8cae8819a1ea8a1da38fe42dc0 339 SUPERFAMILY SSF55821 9 209 4.88E-69 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A3L01_06185 4c22ae8cae8819a1ea8a1da38fe42dc0 339 Gene3D G3DSA:3.90.870.10 3 212 4.3E-86 T 23-10-2018 A3L01_00965 e56b095022df430a9de09b1bb9a9184c 395 Gene3D G3DSA:3.90.1150.10 13 382 1.1E-64 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L01_00965 e56b095022df430a9de09b1bb9a9184c 395 Gene3D G3DSA:3.40.640.10 25 298 1.1E-64 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L01_00965 e56b095022df430a9de09b1bb9a9184c 395 SUPERFAMILY SSF53383 2 388 3.46E-56 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L01_00965 e56b095022df430a9de09b1bb9a9184c 395 Pfam PF00266 Aminotransferase class-V 73 235 1.2E-20 T 23-10-2018 IPR000192 Aminotransferase class V domain A3L01_06675 da9ba9ff6d90e80468f58e108202681e 338 Pfam PF11495 Archaeal transcriptional regulator TrmB 111 336 1.8E-47 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal A3L01_06675 da9ba9ff6d90e80468f58e108202681e 338 SUPERFAMILY SSF46785 3 97 3.55E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_06675 da9ba9ff6d90e80468f58e108202681e 338 Gene3D G3DSA:1.10.10.10 3 102 3.8E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_06675 da9ba9ff6d90e80468f58e108202681e 338 SUPERFAMILY SSF159071 249 337 1.11E-20 T 23-10-2018 A3L01_06675 da9ba9ff6d90e80468f58e108202681e 338 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 77 6.3E-21 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L01_08805 5ee89a006e3b2f9563b263b93b4a4581 164 Gene3D G3DSA:3.30.70.3270 46 163 1.0E-14 T 23-10-2018 A3L01_08805 5ee89a006e3b2f9563b263b93b4a4581 164 SUPERFAMILY SSF54862 54 110 1.72E-18 T 23-10-2018 A3L01_08805 5ee89a006e3b2f9563b263b93b4a4581 164 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 97 108 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_08805 5ee89a006e3b2f9563b263b93b4a4581 164 Pfam PF13237 4Fe-4S dicluster domain 59 108 6.0E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_08805 5ee89a006e3b2f9563b263b93b4a4581 164 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 66 77 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_09945 88c34b8f160a50b13f49bf3d0e818019 294 Pfam PF00892 EamA-like transporter family 147 273 2.7E-25 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L01_09945 88c34b8f160a50b13f49bf3d0e818019 294 Pfam PF00892 EamA-like transporter family 3 137 6.9E-24 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L01_09945 88c34b8f160a50b13f49bf3d0e818019 294 SUPERFAMILY SSF103481 181 278 1.14E-18 T 23-10-2018 A3L01_09945 88c34b8f160a50b13f49bf3d0e818019 294 SUPERFAMILY SSF103481 38 141 7.06E-15 T 23-10-2018 A3L01_09945 88c34b8f160a50b13f49bf3d0e818019 294 Gene3D G3DSA:1.10.3730.20 188 281 6.0E-6 T 23-10-2018 A3L01_06350 e3b5d62729391b1c9ffdfe6bdd9db3c3 132 SMART SM00232 2 129 5.4E-13 T 23-10-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 A3L01_06350 e3b5d62729391b1c9ffdfe6bdd9db3c3 132 Pfam PF14464 Prokaryotic homologs of the JAB domain 17 109 4.2E-14 T 23-10-2018 IPR028090 JAB domain, prokaryotic A3L01_06350 e3b5d62729391b1c9ffdfe6bdd9db3c3 132 SUPERFAMILY SSF102712 1 126 4.58E-23 T 23-10-2018 A3L01_06350 e3b5d62729391b1c9ffdfe6bdd9db3c3 132 Gene3D G3DSA:3.40.140.10 2 132 1.0E-26 T 23-10-2018 A3L01_09160 a4d36487a5a82680e2b6fa5ba19643f8 457 SUPERFAMILY SSF51011 384 457 1.73E-38 T 23-10-2018 A3L01_09160 a4d36487a5a82680e2b6fa5ba19643f8 457 SUPERFAMILY SSF51445 29 381 3.62E-72 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L01_09160 a4d36487a5a82680e2b6fa5ba19643f8 457 PIRSF PIRSF001021 2 457 2.6E-117 T 23-10-2018 IPR013776 Alpha-amylase, thermostable GO:0004553|GO:0005509|GO:0005975 KEGG: 00500+3.2.1.1 A3L01_09160 a4d36487a5a82680e2b6fa5ba19643f8 457 Pfam PF09154 Domain of unknown function (DUF1939) 386 452 1.1E-21 T 23-10-2018 IPR015237 Alpha-amylase C-terminal, prokaryotic GO:0004553 A3L01_09160 a4d36487a5a82680e2b6fa5ba19643f8 457 Pfam PF00128 Alpha amylase, catalytic domain 52 313 5.3E-11 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L01_09160 a4d36487a5a82680e2b6fa5ba19643f8 457 Gene3D G3DSA:2.60.40.1180 360 457 4.9E-52 T 23-10-2018 IPR013780 Glycosyl hydrolase, all-beta A3L01_09160 a4d36487a5a82680e2b6fa5ba19643f8 457 SMART SM00642 32 377 1.5E-27 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L01_09160 a4d36487a5a82680e2b6fa5ba19643f8 457 Gene3D G3DSA:3.20.20.80 24 359 4.3E-107 T 23-10-2018 A3L01_08285 64a30cd79205b0f3ba084023e0ffb121 91 PRINTS PR00112 Acylphosphatase signature 5 20 6.0E-10 T 23-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L01_08285 64a30cd79205b0f3ba084023e0ffb121 91 PRINTS PR00112 Acylphosphatase signature 26 51 6.0E-10 T 23-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L01_08285 64a30cd79205b0f3ba084023e0ffb121 91 ProSitePatterns PS00150 Acylphosphatase signature 1. 10 20 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L01_08285 64a30cd79205b0f3ba084023e0ffb121 91 SUPERFAMILY SSF54975 2 89 1.35E-30 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L01_08285 64a30cd79205b0f3ba084023e0ffb121 91 ProSitePatterns PS00151 Acylphosphatase signature 2. 34 50 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L01_08285 64a30cd79205b0f3ba084023e0ffb121 91 Pfam PF00708 Acylphosphatase 7 88 6.8E-27 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L01_08285 64a30cd79205b0f3ba084023e0ffb121 91 Gene3D G3DSA:3.30.70.100 1 91 6.1E-37 T 23-10-2018 A3L01_01530 f11ae2e822c225966b87e1aaefd44cc3 527 SUPERFAMILY SSF161070 4 496 1.44E-110 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 A3L01_01530 f11ae2e822c225966b87e1aaefd44cc3 527 Pfam PF00209 Sodium:neurotransmitter symporter family 4 132 5.9E-24 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L01_01530 f11ae2e822c225966b87e1aaefd44cc3 527 Pfam PF00209 Sodium:neurotransmitter symporter family 161 459 8.1E-31 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L01_01530 f11ae2e822c225966b87e1aaefd44cc3 527 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 397 417 1.8E-18 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L01_01530 f11ae2e822c225966b87e1aaefd44cc3 527 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 320 339 1.8E-18 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L01_01530 f11ae2e822c225966b87e1aaefd44cc3 527 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 1.8E-18 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L01_01530 f11ae2e822c225966b87e1aaefd44cc3 527 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 1.8E-18 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L01_01530 f11ae2e822c225966b87e1aaefd44cc3 527 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 28 42 - T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L01_09085 556283424a61c9eacb226e11095483d1 354 Gene3D G3DSA:1.10.150.20 40 103 2.2E-25 T 23-10-2018 A3L01_09085 556283424a61c9eacb226e11095483d1 354 PIRSF PIRSF005856 29 354 7.4E-137 T 23-10-2018 IPR016467 DNA recombination and repair protein, RecA-like Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 A3L01_09085 556283424a61c9eacb226e11095483d1 354 SUPERFAMILY SSF52540 116 353 2.36E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_09085 556283424a61c9eacb226e11095483d1 354 Gene3D G3DSA:3.40.50.300 104 354 6.3E-85 T 23-10-2018 A3L01_09085 556283424a61c9eacb226e11095483d1 354 Hamap MF_00348 DNA repair and recombination protein RadA [radA]. 39 354 81.626 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 A3L01_09085 556283424a61c9eacb226e11095483d1 354 SMART SM00382 135 324 3.0E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_09085 556283424a61c9eacb226e11095483d1 354 SUPERFAMILY SSF47794 40 98 2.67E-13 T 23-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 A3L01_09085 556283424a61c9eacb226e11095483d1 354 Pfam PF08423 Rad51 102 354 1.1E-93 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 A3L01_09085 556283424a61c9eacb226e11095483d1 354 Pfam PF14520 Helix-hairpin-helix domain 40 95 3.3E-12 T 23-10-2018 A3L01_09085 556283424a61c9eacb226e11095483d1 354 TIGRFAM TIGR02236 recomb_radA: DNA repair and recombination protein RadA 42 354 4.4E-165 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 A3L01_09085 556283424a61c9eacb226e11095483d1 354 SMART SM00278 73 92 360.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L01_09085 556283424a61c9eacb226e11095483d1 354 SMART SM00278 40 59 0.011 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L01_05890 b17a52e4eba727fb728c286450f469ed 412 Gene3D G3DSA:3.90.550.10 47 267 7.3E-49 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_05890 b17a52e4eba727fb728c286450f469ed 412 Pfam PF13641 Glycosyltransferase like family 2 57 283 2.7E-39 T 23-10-2018 A3L01_05890 b17a52e4eba727fb728c286450f469ed 412 SUPERFAMILY SSF53448 46 316 7.39E-61 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_00620 77fccc2d592bc85198372f843f0f08ea 619 Pfam PF01935 Domain of unknown function DUF87 176 438 2.8E-16 T 23-10-2018 IPR002789 Helicase HerA, central domain A3L01_00620 77fccc2d592bc85198372f843f0f08ea 619 Gene3D G3DSA:3.40.50.300 412 602 7.5E-23 T 23-10-2018 A3L01_00620 77fccc2d592bc85198372f843f0f08ea 619 Gene3D G3DSA:3.40.50.300 158 303 7.6E-14 T 23-10-2018 A3L01_00620 77fccc2d592bc85198372f843f0f08ea 619 SUPERFAMILY SSF52540 184 559 6.25E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_03395 fff2295daf39e328f34936c8b5e5a68e 248 SMART SM00382 26 226 1.4E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_03395 fff2295daf39e328f34936c8b5e5a68e 248 Gene3D G3DSA:3.40.50.300 1 243 1.7E-57 T 23-10-2018 A3L01_03395 fff2295daf39e328f34936c8b5e5a68e 248 Pfam PF00005 ABC transporter 17 167 1.6E-23 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_03395 fff2295daf39e328f34936c8b5e5a68e 248 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_03395 fff2295daf39e328f34936c8b5e5a68e 248 SUPERFAMILY SSF52540 2 223 1.74E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_03395 fff2295daf39e328f34936c8b5e5a68e 248 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 240 2.0E-82 T 23-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 A3L01_04515 fd88a506fa76bde2185193be5606c0f1 527 Pfam PF12161 HsdM N-terminal domain 24 157 2.2E-18 T 23-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain A3L01_04515 fd88a506fa76bde2185193be5606c0f1 527 SUPERFAMILY SSF53335 23 518 1.09E-129 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_04515 fd88a506fa76bde2185193be5606c0f1 527 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 295 301 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A3L01_04515 fd88a506fa76bde2185193be5606c0f1 527 Gene3D G3DSA:1.20.1260.30 14 159 7.1E-8 T 23-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily A3L01_04515 fd88a506fa76bde2185193be5606c0f1 527 Gene3D G3DSA:3.40.50.150 167 467 1.9E-100 T 23-10-2018 A3L01_04515 fd88a506fa76bde2185193be5606c0f1 527 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 213 227 2.5E-18 T 23-10-2018 A3L01_04515 fd88a506fa76bde2185193be5606c0f1 527 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 292 304 2.5E-18 T 23-10-2018 A3L01_04515 fd88a506fa76bde2185193be5606c0f1 527 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 330 354 2.5E-18 T 23-10-2018 A3L01_04515 fd88a506fa76bde2185193be5606c0f1 527 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 189 205 2.5E-18 T 23-10-2018 A3L01_04515 fd88a506fa76bde2185193be5606c0f1 527 Pfam PF02384 N-6 DNA Methylase 166 483 1.1E-116 T 23-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A3L01_07240 e0b6bb45cc4d1f58720cee29e748985c 386 PIRSF PIRSF000429 1 383 1.1E-65 T 23-10-2018 IPR002155 Thiolase GO:0016747 A3L01_07240 e0b6bb45cc4d1f58720cee29e748985c 386 Pfam PF02803 Thiolase, C-terminal domain 251 355 3.5E-10 T 23-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 A3L01_07240 e0b6bb45cc4d1f58720cee29e748985c 386 SUPERFAMILY SSF53901 247 373 8.36E-29 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L01_07240 e0b6bb45cc4d1f58720cee29e748985c 386 Gene3D G3DSA:3.40.47.10 4 385 3.9E-122 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L01_07240 e0b6bb45cc4d1f58720cee29e748985c 386 SUPERFAMILY SSF53901 4 229 1.22E-44 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L01_07240 e0b6bb45cc4d1f58720cee29e748985c 386 Pfam PF00108 Thiolase, N-terminal domain 5 220 3.8E-26 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 A3L01_07325 81db76c73e3a154e71868c407fa3723d 142 Pfam PF04024 PspC domain 4 61 2.0E-19 T 23-10-2018 IPR007168 Phage shock protein, PspC, N-terminal A3L01_08510 b782ad66de0c453933a926c12dfd2762 83 Hamap MF_00342 UPF0147 protein . 1 83 29.55 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 A3L01_08510 b782ad66de0c453933a926c12dfd2762 83 Pfam PF03685 Uncharacterised protein family (UPF0147) 3 82 3.5E-33 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 A3L01_08510 b782ad66de0c453933a926c12dfd2762 83 ProDom PD029943 UPF0147 ARCHAEAL PF0239 ST0460.1 MM1385 CYTOSOLIC SACI_0891 TV0625 APES069 TA0600 1 83 3.0E-38 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 A3L01_08510 b782ad66de0c453933a926c12dfd2762 83 SUPERFAMILY SSF158436 3 83 1.44E-29 T 23-10-2018 A3L01_08510 b782ad66de0c453933a926c12dfd2762 83 Gene3D G3DSA:1.20.1440.50 2 83 3.2E-31 T 23-10-2018 IPR023130 Ta0600-like superfamily A3L01_02650 ba24e579660cb773131c2e37acc44955 305 Pfam PF13732 Domain of unknown function (DUF4162) 222 304 4.7E-7 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 A3L01_02650 ba24e579660cb773131c2e37acc44955 305 Pfam PF00005 ABC transporter 17 167 1.2E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_02650 ba24e579660cb773131c2e37acc44955 305 SUPERFAMILY SSF52540 2 229 4.47E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_02650 ba24e579660cb773131c2e37acc44955 305 SMART SM00382 26 229 5.7E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_02650 ba24e579660cb773131c2e37acc44955 305 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_02650 ba24e579660cb773131c2e37acc44955 305 Gene3D G3DSA:3.40.50.300 1 240 7.8E-59 T 23-10-2018 A3L01_08895 45f01be8a4a66d7eb537719b81cc4bd7 150 SUPERFAMILY SSF54909 65 147 9.92E-17 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L01_08895 45f01be8a4a66d7eb537719b81cc4bd7 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 4.3E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_08895 45f01be8a4a66d7eb537719b81cc4bd7 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 4.3E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_08895 45f01be8a4a66d7eb537719b81cc4bd7 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 4.3E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_08895 45f01be8a4a66d7eb537719b81cc4bd7 150 Gene3D G3DSA:1.10.10.10 2 56 6.2E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_08895 45f01be8a4a66d7eb537719b81cc4bd7 150 Pfam PF01037 Lrp/AsnC ligand binding domain 78 142 1.8E-14 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L01_08895 45f01be8a4a66d7eb537719b81cc4bd7 150 Gene3D G3DSA:3.30.70.920 59 150 1.3E-22 T 23-10-2018 A3L01_08895 45f01be8a4a66d7eb537719b81cc4bd7 150 SMART SM00344 5 114 4.0E-43 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L01_08895 45f01be8a4a66d7eb537719b81cc4bd7 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 52 1.6E-15 T 23-10-2018 A3L01_08895 45f01be8a4a66d7eb537719b81cc4bd7 150 SUPERFAMILY SSF46785 4 77 4.28E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_08905 66ebf9347334265768d1f51ebf838ef7 162 SUPERFAMILY SSF103165 2 160 2.88E-60 T 23-10-2018 IPR036902 Ta1353-like superfamily A3L01_08905 66ebf9347334265768d1f51ebf838ef7 162 Gene3D G3DSA:3.40.1520.10 1 162 1.4E-71 T 23-10-2018 IPR036902 Ta1353-like superfamily A3L01_08905 66ebf9347334265768d1f51ebf838ef7 162 Pfam PF04008 Adenosine specific kinase 7 160 3.7E-62 T 23-10-2018 IPR007153 Adenosine specific kinase A3L01_06850 3fde298f4d188804571ecd150af170ba 427 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 295 317 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A3L01_06850 3fde298f4d188804571ecd150af170ba 427 Gene3D G3DSA:1.20.120.1760 230 423 1.6E-57 T 23-10-2018 A3L01_06850 3fde298f4d188804571ecd150af170ba 427 Pfam PF01066 CDP-alcohol phosphatidyltransferase 254 317 9.6E-10 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A3L01_06850 3fde298f4d188804571ecd150af170ba 427 Pfam PF12804 MobA-like NTP transferase domain 6 114 7.4E-16 T 23-10-2018 IPR025877 MobA-like NTP transferase A3L01_06850 3fde298f4d188804571ecd150af170ba 427 Gene3D G3DSA:3.90.550.10 4 220 6.0E-55 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_06850 3fde298f4d188804571ecd150af170ba 427 SUPERFAMILY SSF53448 5 221 5.63E-33 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_09845 e8ee5bce57d0303f9ead424b3914842c 585 Gene3D G3DSA:1.10.1140.10 435 585 1.1E-60 T 23-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L01_09845 e8ee5bce57d0303f9ead424b3914842c 585 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 82 202 1.4E-47 T 23-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L01_09845 e8ee5bce57d0303f9ead424b3914842c 585 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 1 583 55.018 T 23-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L01_09845 e8ee5bce57d0303f9ead424b3914842c 585 Gene3D G3DSA:2.40.30.20 1 69 8.3E-30 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L01_09845 e8ee5bce57d0303f9ead424b3914842c 585 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 425 434 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L01_09845 e8ee5bce57d0303f9ead424b3914842c 585 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 211 434 2.5E-92 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L01_09845 e8ee5bce57d0303f9ead424b3914842c 585 Gene3D G3DSA:2.40.50.100 113 184 1.2E-185 T 23-10-2018 A3L01_09845 e8ee5bce57d0303f9ead424b3914842c 585 SMART SM00382 223 411 0.0028 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_09845 e8ee5bce57d0303f9ead424b3914842c 585 TIGRFAM TIGR01043 ATP_syn_A_arch: ATP synthase archaeal, A subunit 1 580 0.0 T 23-10-2018 IPR005726 ATP synthase alpha chain, archaea GO:0015986|GO:0033178|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L01_09845 e8ee5bce57d0303f9ead424b3914842c 585 SUPERFAMILY SSF47917 446 552 1.26E-27 T 23-10-2018 A3L01_09845 e8ee5bce57d0303f9ead424b3914842c 585 SUPERFAMILY SSF50615 1 68 2.46E-13 T 23-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L01_09845 e8ee5bce57d0303f9ead424b3914842c 585 SUPERFAMILY SSF52540 163 440 1.8E-85 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_09845 e8ee5bce57d0303f9ead424b3914842c 585 Gene3D G3DSA:3.40.50.300 70 434 1.2E-185 T 23-10-2018 A3L01_09845 e8ee5bce57d0303f9ead424b3914842c 585 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 4 66 1.5E-14 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L01_07505 fc1e01ce957061220d3d03b955661c6a 375 Pfam PF13186 Iron-sulfur cluster-binding domain 252 330 3.7E-16 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A3L01_07505 fc1e01ce957061220d3d03b955661c6a 375 SMART SM00729 24 235 9.4E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L01_07505 fc1e01ce957061220d3d03b955661c6a 375 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 30 41 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L01_07505 fc1e01ce957061220d3d03b955661c6a 375 Gene3D G3DSA:3.20.20.70 19 308 7.8E-46 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_07505 fc1e01ce957061220d3d03b955661c6a 375 Pfam PF13353 4Fe-4S single cluster domain 31 120 6.3E-6 T 23-10-2018 A3L01_07505 fc1e01ce957061220d3d03b955661c6a 375 Pfam PF04055 Radical SAM superfamily 28 189 2.0E-17 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L01_07505 fc1e01ce957061220d3d03b955661c6a 375 TIGRFAM TIGR04317 W_rSAM_matur: tungsten cofactor oxidoreducase radical SAM maturase 22 365 8.9E-151 T 23-10-2018 IPR027604 Tungsten cofactor oxidoreducase radical SAM maturase A3L01_07505 fc1e01ce957061220d3d03b955661c6a 375 SUPERFAMILY SSF102114 24 335 3.66E-55 T 23-10-2018 A3L01_07485 973a1ef41bca9c062e226162ad93ba3f 301 SUPERFAMILY SSF51395 1 298 7.33E-84 T 23-10-2018 A3L01_07485 973a1ef41bca9c062e226162ad93ba3f 301 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 298 1.2E-129 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A3L01_07485 973a1ef41bca9c062e226162ad93ba3f 301 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 298 36.91 T 23-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 A3L01_07485 973a1ef41bca9c062e226162ad93ba3f 301 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 235 255 - T 23-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A3L01_07485 973a1ef41bca9c062e226162ad93ba3f 301 Gene3D G3DSA:2.30.26.10 55 212 1.2E-93 T 23-10-2018 IPR023359 Dihydroorotate dehydrogenase A, chain A, domain 2 A3L01_07485 973a1ef41bca9c062e226162ad93ba3f 301 Pfam PF01180 Dihydroorotate dehydrogenase 4 280 2.4E-63 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A3L01_07485 973a1ef41bca9c062e226162ad93ba3f 301 Gene3D G3DSA:3.20.20.70 12 289 1.2E-93 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_07485 973a1ef41bca9c062e226162ad93ba3f 301 PIRSF PIRSF000164 1 300 1.7E-87 T 23-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 A3L01_07485 973a1ef41bca9c062e226162ad93ba3f 301 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 40 59 - T 23-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A3L01_08415 d3d88a023c5696b07da5c476843986e1 417 SUPERFAMILY SSF53335 60 413 6.26E-71 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_08415 d3d88a023c5696b07da5c476843986e1 417 Gene3D G3DSA:3.40.50.150 73 410 5.8E-117 T 23-10-2018 A3L01_08415 d3d88a023c5696b07da5c476843986e1 417 SUPERFAMILY SSF50249 4 58 1.26E-8 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_08415 d3d88a023c5696b07da5c476843986e1 417 Gene3D G3DSA:2.40.50.140 1 61 8.2E-14 T 23-10-2018 A3L01_08415 d3d88a023c5696b07da5c476843986e1 417 Gene3D G3DSA:3.40.1350.30 112 257 5.8E-117 T 23-10-2018 A3L01_08415 d3d88a023c5696b07da5c476843986e1 417 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 347 378 - T 23-10-2018 IPR030390 RNA methyltransferase TrmA, active site A3L01_08415 d3d88a023c5696b07da5c476843986e1 417 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 8 408 7.2E-84 T 23-10-2018 A3L01_08415 d3d88a023c5696b07da5c476843986e1 417 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 398 408 - T 23-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site A3L01_08415 d3d88a023c5696b07da5c476843986e1 417 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 246 414 5.0E-22 T 23-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A3L01_06790 9d053bcacbe283cb960ebb5801deb6c3 443 SUPERFAMILY SSF51649 135 440 6.28E-106 T 23-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L01_06790 9d053bcacbe283cb960ebb5801deb6c3 443 Hamap MF_01133 Ribulose bisphosphate carboxylase [rbcL]. 9 438 53.067 T 23-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L01_06790 9d053bcacbe283cb960ebb5801deb6c3 443 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 146 437 2.1E-98 T 23-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L01_06790 9d053bcacbe283cb960ebb5801deb6c3 443 Gene3D G3DSA:3.30.70.150 1 135 2.1E-44 T 23-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L01_06790 9d053bcacbe283cb960ebb5801deb6c3 443 TIGRFAM TIGR03326 rubisco_III: ribulose bisphosphate carboxylase, type III 11 437 1.7E-217 T 23-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L01_06790 9d053bcacbe283cb960ebb5801deb6c3 443 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 11 131 8.0E-48 T 23-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L01_06790 9d053bcacbe283cb960ebb5801deb6c3 443 SUPERFAMILY SSF54966 11 136 2.22E-39 T 23-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L01_06790 9d053bcacbe283cb960ebb5801deb6c3 443 Gene3D G3DSA:3.20.20.110 136 437 3.1E-121 T 23-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L01_03030 30dd13cc06b0bf91c95b925824fdb6c0 440 Pfam PF06068 TIP49 C-terminus 14 403 1.3E-160 T 23-10-2018 IPR010339 TIP49, C-terminal GO:0003678|GO:0005524 Reactome: R-HSA-171319|Reactome: R-HSA-3214847 A3L01_03030 30dd13cc06b0bf91c95b925824fdb6c0 440 SUPERFAMILY SSF50249 126 207 6.34E-20 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_03030 30dd13cc06b0bf91c95b925824fdb6c0 440 SUPERFAMILY SSF52540 37 423 5.82E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_03030 30dd13cc06b0bf91c95b925824fdb6c0 440 Gene3D G3DSA:1.10.8.60 354 438 1.8E-25 T 23-10-2018 A3L01_03030 30dd13cc06b0bf91c95b925824fdb6c0 440 Gene3D G3DSA:3.40.50.300 18 349 8.3E-113 T 23-10-2018 A3L01_03030 30dd13cc06b0bf91c95b925824fdb6c0 440 SMART SM00382 62 353 8.2E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_03030 30dd13cc06b0bf91c95b925824fdb6c0 440 Gene3D G3DSA:2.40.50.360 119 243 8.3E-113 T 23-10-2018 A3L01_01080 af2ae9b5216e42c66a1cc86ac7641937 111 ProSitePatterns PS00056 Ribosomal protein S17 signature. 82 94 - T 23-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01080 af2ae9b5216e42c66a1cc86ac7641937 111 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 31 102 1.0E-32 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01080 af2ae9b5216e42c66a1cc86ac7641937 111 PRINTS PR00973 Ribosomal protein S17 family signature 82 92 3.9E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01080 af2ae9b5216e42c66a1cc86ac7641937 111 PRINTS PR00973 Ribosomal protein S17 family signature 49 72 3.9E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01080 af2ae9b5216e42c66a1cc86ac7641937 111 PRINTS PR00973 Ribosomal protein S17 family signature 92 99 3.9E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01080 af2ae9b5216e42c66a1cc86ac7641937 111 TIGRFAM TIGR03630 uS17_arch: ribosomal protein uS17 4 104 3.4E-47 T 23-10-2018 IPR028333 Ribosomal protein S17, archaeal/eukaryotic Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01080 af2ae9b5216e42c66a1cc86ac7641937 111 Hamap MF_01345_A 30S ribosomal protein S17 [rpsQ]. 2 106 33.319 T 23-10-2018 IPR019978 Ribosomal protein S17, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01080 af2ae9b5216e42c66a1cc86ac7641937 111 SUPERFAMILY SSF50249 29 109 1.17E-28 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_01080 af2ae9b5216e42c66a1cc86ac7641937 111 Pfam PF00366 Ribosomal protein S17 35 102 5.3E-27 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01080 af2ae9b5216e42c66a1cc86ac7641937 111 Gene3D G3DSA:2.40.50.1000 1 111 1.7E-38 T 23-10-2018 A3L01_05505 99eca032cd84cdeec6a7209dc5a5142d 416 Pfam PF01979 Amidohydrolase family 52 395 2.4E-57 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A3L01_05505 99eca032cd84cdeec6a7209dc5a5142d 416 Gene3D G3DSA:2.30.40.10 5 403 1.3E-114 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L01_05505 99eca032cd84cdeec6a7209dc5a5142d 416 Gene3D G3DSA:3.20.20.140 55 341 1.3E-114 T 23-10-2018 A3L01_05505 99eca032cd84cdeec6a7209dc5a5142d 416 SUPERFAMILY SSF51338 13 404 2.16E-23 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L01_05505 99eca032cd84cdeec6a7209dc5a5142d 416 SUPERFAMILY SSF51556 54 343 9.53E-79 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L01_09190 cef431424e71a531a06402a2aa88a265 383 Gene3D G3DSA:3.40.50.620 1 255 9.6E-103 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_09190 cef431424e71a531a06402a2aa88a265 383 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 85 101 1.5E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L01_09190 cef431424e71a531a06402a2aa88a265 383 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 252 262 1.5E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L01_09190 cef431424e71a531a06402a2aa88a265 383 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 208 229 1.5E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L01_09190 cef431424e71a531a06402a2aa88a265 383 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 138 157 1.5E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L01_09190 cef431424e71a531a06402a2aa88a265 383 Gene3D G3DSA:1.10.240.10 256 381 2.9E-44 T 23-10-2018 A3L01_09190 cef431424e71a531a06402a2aa88a265 383 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 81 90 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_09190 cef431424e71a531a06402a2aa88a265 383 Pfam PF00579 tRNA synthetases class I (W and Y) 73 347 8.2E-25 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_09190 cef431424e71a531a06402a2aa88a265 383 SUPERFAMILY SSF52374 4 368 1.91E-90 T 23-10-2018 A3L01_09190 cef431424e71a531a06402a2aa88a265 383 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 72 378 2.5E-105 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L01_09190 cef431424e71a531a06402a2aa88a265 383 Hamap MF_00140_A Tryptophan--tRNA ligase [trpS]. 5 366 46.205 T 23-10-2018 IPR020653 Tryptophan-tRNA ligase, archaea GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L01_09875 f4b92190e4638e36397a0de15f3448fa 418 Gene3D G3DSA:1.10.3720.10 202 412 6.2E-14 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_09875 f4b92190e4638e36397a0de15f3448fa 418 SUPERFAMILY SSF161098 204 402 9.55E-15 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_09875 f4b92190e4638e36397a0de15f3448fa 418 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 229 407 1.5E-11 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_07280 d8f9b832f7ea450eff84225deb4514db 288 SUPERFAMILY SSF52317 3 239 4.38E-32 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_07280 d8f9b832f7ea450eff84225deb4514db 288 Pfam PF07722 Peptidase C26 3 219 3.8E-51 T 23-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 A3L01_07280 d8f9b832f7ea450eff84225deb4514db 288 Gene3D G3DSA:3.40.50.880 1 245 2.8E-65 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_08240 5da340c6299840c738166b48eb6b3a90 201 Pfam PF13247 4Fe-4S dicluster domain 60 151 1.1E-26 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_08240 5da340c6299840c738166b48eb6b3a90 201 PRINTS PR00354 7Fe ferredoxin signature 74 84 4.1E-5 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 A3L01_08240 5da340c6299840c738166b48eb6b3a90 201 PRINTS PR00354 7Fe ferredoxin signature 91 108 4.1E-5 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 A3L01_08240 5da340c6299840c738166b48eb6b3a90 201 PRINTS PR00354 7Fe ferredoxin signature 64 74 4.1E-5 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 A3L01_08240 5da340c6299840c738166b48eb6b3a90 201 SUPERFAMILY SSF54862 5 165 2.72E-57 T 23-10-2018 A3L01_08240 5da340c6299840c738166b48eb6b3a90 201 Gene3D G3DSA:3.30.70.20 50 182 3.9E-44 T 23-10-2018 A3L01_08240 5da340c6299840c738166b48eb6b3a90 201 Pfam PF12837 4Fe-4S binding domain 9 27 2.0E-5 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_08240 5da340c6299840c738166b48eb6b3a90 201 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 96 107 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_04345 5ec64dbc96a91568bc6c8229c6c09a60 709 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 583 664 2.3E-6 T 23-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain A3L01_04345 5ec64dbc96a91568bc6c8229c6c09a60 709 SUPERFAMILY SSF49464 385 466 1.02E-7 T 23-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily A3L01_04345 5ec64dbc96a91568bc6c8229c6c09a60 709 Gene3D G3DSA:2.60.40.1120 381 453 1.1E-8 T 23-10-2018 A3L01_05895 55af0ccb97f21fc7f1ea3d3e9daf24b7 235 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 7 233 4.1E-52 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein A3L01_05895 55af0ccb97f21fc7f1ea3d3e9daf24b7 235 Pfam PF03749 Sugar fermentation stimulation protein 15 220 8.8E-48 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein A3L01_05895 55af0ccb97f21fc7f1ea3d3e9daf24b7 235 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 4 234 38.595 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein A3L01_05895 55af0ccb97f21fc7f1ea3d3e9daf24b7 235 Gene3D G3DSA:3.40.1350.60 80 233 1.2E-41 T 23-10-2018 A3L01_05895 55af0ccb97f21fc7f1ea3d3e9daf24b7 235 Gene3D G3DSA:2.40.50.580 1 79 1.5E-24 T 23-10-2018 A3L01_10180 02b5ff9771eb7bc33b4e442d5b37bd33 329 PIRSF PIRSF018671 1 329 7.2E-124 T 23-10-2018 IPR014495 Uncharacterised conserved protein UCP018671 A3L01_10180 02b5ff9771eb7bc33b4e442d5b37bd33 329 Pfam PF07760 Protein of unknown function (DUF1616) 12 325 2.1E-92 T 23-10-2018 IPR011674 Domain of unknown function DUF1616 A3L01_09565 8def6d98dc1bfa845158ade637ef5629 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 415 437 4.5E-10 T 23-10-2018 A3L01_09565 8def6d98dc1bfa845158ade637ef5629 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 4.5E-10 T 23-10-2018 A3L01_09565 8def6d98dc1bfa845158ade637ef5629 484 Gene3D G3DSA:3.50.50.60 416 456 1.6E-6 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_09565 8def6d98dc1bfa845158ade637ef5629 484 Pfam PF03486 HI0933-like protein 7 45 6.8E-6 T 23-10-2018 A3L01_09565 8def6d98dc1bfa845158ade637ef5629 484 Gene3D G3DSA:3.50.50.60 2 90 1.9E-18 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_09565 8def6d98dc1bfa845158ade637ef5629 484 SUPERFAMILY SSF51905 5 459 6.75E-31 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_09565 8def6d98dc1bfa845158ade637ef5629 484 PIRSF PIRSF038984 2 85 9.2E-9 T 23-10-2018 IPR028348 FAD dependent protein A3L01_09565 8def6d98dc1bfa845158ade637ef5629 484 PIRSF PIRSF038984 131 463 1.0E-24 T 23-10-2018 IPR028348 FAD dependent protein A3L01_10240 f47de924cbb0c266d6b7caa6745f9e7d 350 Pfam PF00535 Glycosyl transferase family 2 7 85 2.1E-8 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L01_10240 f47de924cbb0c266d6b7caa6745f9e7d 350 SUPERFAMILY SSF53448 2 318 2.1E-49 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_10240 f47de924cbb0c266d6b7caa6745f9e7d 350 Gene3D G3DSA:3.90.550.10 2 276 2.8E-43 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_10240 f47de924cbb0c266d6b7caa6745f9e7d 350 Pfam PF13641 Glycosyltransferase like family 2 102 270 2.9E-12 T 23-10-2018 A3L01_05465 4935773835bf07e15bcab3fc08921c7b 70 Pfam PF01200 Ribosomal protein S28e 4 66 7.7E-29 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_05465 4935773835bf07e15bcab3fc08921c7b 70 SUPERFAMILY SSF50249 3 69 1.97E-24 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_05465 4935773835bf07e15bcab3fc08921c7b 70 Gene3D G3DSA:2.40.50.140 1 70 7.6E-32 T 23-10-2018 A3L01_05465 4935773835bf07e15bcab3fc08921c7b 70 ProSitePatterns PS00961 Ribosomal protein S28e signature. 58 66 - T 23-10-2018 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_05465 4935773835bf07e15bcab3fc08921c7b 70 ProDom PD005541 RIBOSOMAL RIBONUCLEOPROTEIN 40S S28 S28E 30S ACETYLATION S33 S33 CG15527 1 48 2.0E-8 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_05465 4935773835bf07e15bcab3fc08921c7b 70 Hamap MF_00292 30S ribosomal protein S28e [rps28e]. 1 67 24.833 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_07270 b38d22f580b463f8666391a61b9513aa 322 Gene3D G3DSA:1.20.120.420 1 114 8.4E-47 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L01_07270 b38d22f580b463f8666391a61b9513aa 322 SUPERFAMILY SSF100950 4 311 5.02E-101 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L01_07270 b38d22f580b463f8666391a61b9513aa 322 Pfam PF01008 Initiation factor 2 subunit family 19 299 3.6E-93 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A3L01_07270 b38d22f580b463f8666391a61b9513aa 322 Gene3D G3DSA:3.40.50.10470 115 310 1.3E-84 T 23-10-2018 A3L01_07270 b38d22f580b463f8666391a61b9513aa 322 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 5 299 1.1E-97 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L01_07270 b38d22f580b463f8666391a61b9513aa 322 TIGRFAM TIGR00511 ribulose_e2b2: ribose-1,5-bisphosphate isomerase, e2b2 family 6 312 7.9E-147 T 23-10-2018 IPR005250 Ribose-1,5-bisphosphate isomerase, e2b2 family MetaCyc: PWY-5532 A3L01_05200 72f55fb4704f0e19bd0a036a3625ffe5 135 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 133 9.743 T 23-10-2018 IPR022907 VapC family GO:0004540 A3L01_05200 72f55fb4704f0e19bd0a036a3625ffe5 135 SUPERFAMILY SSF88723 1 133 2.78E-22 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L01_05200 72f55fb4704f0e19bd0a036a3625ffe5 135 Gene3D G3DSA:3.40.50.1010 3 131 4.5E-17 T 23-10-2018 A3L01_05200 72f55fb4704f0e19bd0a036a3625ffe5 135 SMART SM00670 1 125 2.1E-10 T 23-10-2018 IPR002716 PIN domain A3L01_05200 72f55fb4704f0e19bd0a036a3625ffe5 135 Pfam PF01850 PIN domain 4 126 2.9E-19 T 23-10-2018 IPR002716 PIN domain A3L01_01840 b515409b25c1c863ff9386c47b836c4a 266 TIGRFAM TIGR00162 TIGR00162: TIGR00162 family protein 8 265 8.6E-75 T 23-10-2018 IPR004426 Conserved hypothetical protein CHP00062 A3L01_01840 b515409b25c1c863ff9386c47b836c4a 266 Gene3D G3DSA:3.40.50.10900 1 244 4.4E-75 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily A3L01_01840 b515409b25c1c863ff9386c47b836c4a 266 SUPERFAMILY SSF159659 3 257 7.45E-43 T 23-10-2018 A3L01_01840 b515409b25c1c863ff9386c47b836c4a 266 Pfam PF09754 PAC2 family 19 242 2.6E-46 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 A3L01_01040 2ea276a6bbbe9d21ec24438b18a641ff 86 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 82 14.626 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A3L01_01040 2ea276a6bbbe9d21ec24438b18a641ff 86 Gene3D G3DSA:3.30.70.330 1 86 5.1E-37 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily A3L01_01040 2ea276a6bbbe9d21ec24438b18a641ff 86 TIGRFAM TIGR03636 uL23_arch: ribosomal protein uL23 10 86 1.7E-39 T 23-10-2018 IPR019985 Ribosomal protein L23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01040 2ea276a6bbbe9d21ec24438b18a641ff 86 ProSitePatterns PS00050 Ribosomal protein L23 signature. 64 79 - T 23-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01040 2ea276a6bbbe9d21ec24438b18a641ff 86 SUPERFAMILY SSF54189 4 78 9.71E-28 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01040 2ea276a6bbbe9d21ec24438b18a641ff 86 Hamap MF_01369_A 50S ribosomal protein L23 [rplW]. 6 86 27.85 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A3L01_01040 2ea276a6bbbe9d21ec24438b18a641ff 86 Pfam PF00276 Ribosomal protein L23 5 73 3.5E-19 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A3L01_10080 b89065a976f09564a6f6e4729a5eb5d9 448 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 179 196 - T 23-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 A3L01_10080 b89065a976f09564a6f6e4729a5eb5d9 448 Pfam PF13416 Bacterial extracellular solute-binding protein 92 387 1.2E-51 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein A3L01_10080 b89065a976f09564a6f6e4729a5eb5d9 448 PRINTS PR00181 Maltose binding protein signature 274 293 1.2E-12 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A3L01_10080 b89065a976f09564a6f6e4729a5eb5d9 448 PRINTS PR00181 Maltose binding protein signature 176 195 1.2E-12 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A3L01_10080 b89065a976f09564a6f6e4729a5eb5d9 448 PRINTS PR00181 Maltose binding protein signature 403 422 1.2E-12 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A3L01_10080 b89065a976f09564a6f6e4729a5eb5d9 448 PRINTS PR00181 Maltose binding protein signature 114 132 1.2E-12 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A3L01_10080 b89065a976f09564a6f6e4729a5eb5d9 448 PRINTS PR00181 Maltose binding protein signature 197 216 1.2E-12 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A3L01_10080 b89065a976f09564a6f6e4729a5eb5d9 448 SUPERFAMILY SSF53850 71 442 6.92E-94 T 23-10-2018 A3L01_10080 b89065a976f09564a6f6e4729a5eb5d9 448 Gene3D G3DSA:3.40.190.10 184 418 8.4E-141 T 23-10-2018 A3L01_10080 b89065a976f09564a6f6e4729a5eb5d9 448 Gene3D G3DSA:3.40.190.10 77 403 8.4E-141 T 23-10-2018 A3L01_08945 312a77526274663c74574c21f28687f0 173 PIRSF PIRSF006707 1 172 3.3E-38 T 23-10-2018 IPR026282 DNA-binding protein, MJ1563 type A3L01_08945 312a77526274663c74574c21f28687f0 173 Pfam PF01047 MarR family 38 81 1.2E-7 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A3L01_08945 312a77526274663c74574c21f28687f0 173 Gene3D G3DSA:1.10.10.10 2 86 4.6E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_08945 312a77526274663c74574c21f28687f0 173 SUPERFAMILY SSF46785 4 118 7.03E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_09375 c04f444e324da6b5f671bc164e1ca9f5 300 SUPERFAMILY SSF53448 4 217 1.97E-67 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_09375 c04f444e324da6b5f671bc164e1ca9f5 300 Gene3D G3DSA:3.90.550.10 1 228 4.8E-74 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_09375 c04f444e324da6b5f671bc164e1ca9f5 300 Pfam PF00535 Glycosyl transferase family 2 7 145 7.5E-39 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L01_00925 0ecb2739893844a3046ed346bcb95532 246 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 15 150 2.4E-24 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_00925 0ecb2739893844a3046ed346bcb95532 246 Gene3D G3DSA:3.40.50.700 4 166 2.6E-35 T 23-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily A3L01_00925 0ecb2739893844a3046ed346bcb95532 246 SUPERFAMILY SSF56770 3 211 4.06E-43 T 23-10-2018 A3L01_03450 574497a74f08b5e8661039e1d8f87ec5 618 Gene3D G3DSA:3.40.50.1980 61 182 2.3E-31 T 23-10-2018 A3L01_03450 574497a74f08b5e8661039e1d8f87ec5 618 Gene3D G3DSA:3.40.50.1980 198 325 1.5E-33 T 23-10-2018 A3L01_03450 574497a74f08b5e8661039e1d8f87ec5 618 SUPERFAMILY SSF53807 338 602 1.18E-72 T 23-10-2018 A3L01_03450 574497a74f08b5e8661039e1d8f87ec5 618 SUPERFAMILY SSF53807 60 327 1.45E-68 T 23-10-2018 A3L01_03450 574497a74f08b5e8661039e1d8f87ec5 618 Gene3D G3DSA:3.40.50.1980 471 598 5.3E-35 T 23-10-2018 A3L01_03450 574497a74f08b5e8661039e1d8f87ec5 618 Pfam PF01497 Periplasmic binding protein 354 573 3.7E-35 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain A3L01_03450 574497a74f08b5e8661039e1d8f87ec5 618 Pfam PF01497 Periplasmic binding protein 83 301 1.9E-34 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain A3L01_03450 574497a74f08b5e8661039e1d8f87ec5 618 Gene3D G3DSA:3.40.50.1980 336 466 3.9E-35 T 23-10-2018 A3L01_02995 7fe180201d52d5cde8ff6547714158dd 49 Hamap MF_00615 DNA-directed RNA polymerase subunit P [rpoP]. 6 49 16.941 T 23-10-2018 IPR023464 DNA-directed RNA polymerase subunit P (Rpo12) GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_02995 7fe180201d52d5cde8ff6547714158dd 49 Pfam PF03604 DNA directed RNA polymerase, 7 kDa subunit 6 39 7.4E-11 T 23-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L01_02995 7fe180201d52d5cde8ff6547714158dd 49 SUPERFAMILY SSF63393 4 48 7.32E-13 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A3L01_02995 7fe180201d52d5cde8ff6547714158dd 49 SMART SM00659 4 49 1.2E-20 T 23-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L01_02995 7fe180201d52d5cde8ff6547714158dd 49 Gene3D G3DSA:2.20.28.30 1 49 1.3E-23 T 23-10-2018 A3L01_04795 e5e2506d13196f902b5e7dae22d06cac 226 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 189 199 - T 23-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L01_04795 e5e2506d13196f902b5e7dae22d06cac 226 Gene3D G3DSA:3.40.50.1860 102 211 4.2E-73 T 23-10-2018 A3L01_04795 e5e2506d13196f902b5e7dae22d06cac 226 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 224 1.8E-49 T 23-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 A3L01_04795 e5e2506d13196f902b5e7dae22d06cac 226 Gene3D G3DSA:3.40.50.1860 4 215 4.2E-73 T 23-10-2018 A3L01_04795 e5e2506d13196f902b5e7dae22d06cac 226 SUPERFAMILY SSF53681 117 224 4.36E-24 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L01_04795 e5e2506d13196f902b5e7dae22d06cac 226 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 220 1.8E-51 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L01_04795 e5e2506d13196f902b5e7dae22d06cac 226 SUPERFAMILY SSF53681 1 114 2.62E-28 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L01_05325 cee7f53e9212a62e06a1394f3c064992 451 Pfam PF10397 Adenylosuccinate lyase C-terminus 362 438 3.5E-18 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L01_05325 cee7f53e9212a62e06a1394f3c064992 451 ProSitePatterns PS00163 Fumarate lyases signature. 272 281 - T 23-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A3L01_05325 cee7f53e9212a62e06a1394f3c064992 451 PRINTS PR00145 Argininosuccinate lyase family signature 272 288 2.3E-11 T 23-10-2018 A3L01_05325 cee7f53e9212a62e06a1394f3c064992 451 PRINTS PR00145 Argininosuccinate lyase family signature 136 156 2.3E-11 T 23-10-2018 A3L01_05325 cee7f53e9212a62e06a1394f3c064992 451 PRINTS PR00145 Argininosuccinate lyase family signature 227 251 2.3E-11 T 23-10-2018 A3L01_05325 cee7f53e9212a62e06a1394f3c064992 451 PRINTS PR00145 Argininosuccinate lyase family signature 95 117 2.3E-11 T 23-10-2018 A3L01_05325 cee7f53e9212a62e06a1394f3c064992 451 Gene3D G3DSA:1.10.275.10 1 100 9.4E-37 T 23-10-2018 IPR024083 Fumarase/histidase, N-terminal A3L01_05325 cee7f53e9212a62e06a1394f3c064992 451 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 6 438 3.2E-184 T 23-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L01_05325 cee7f53e9212a62e06a1394f3c064992 451 Pfam PF00206 Lyase 13 292 6.6E-57 T 23-10-2018 IPR022761 Fumarate lyase, N-terminal A3L01_05325 cee7f53e9212a62e06a1394f3c064992 451 Gene3D G3DSA:1.10.40.30 360 449 6.0E-22 T 23-10-2018 A3L01_05325 cee7f53e9212a62e06a1394f3c064992 451 SMART SM00998 360 439 3.5E-29 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L01_05325 cee7f53e9212a62e06a1394f3c064992 451 PRINTS PR00149 Fumarate lyase superfamily signature 227 254 5.9E-27 T 23-10-2018 IPR000362 Fumarate lyase family A3L01_05325 cee7f53e9212a62e06a1394f3c064992 451 PRINTS PR00149 Fumarate lyase superfamily signature 96 114 5.9E-27 T 23-10-2018 IPR000362 Fumarate lyase family A3L01_05325 cee7f53e9212a62e06a1394f3c064992 451 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 5.9E-27 T 23-10-2018 IPR000362 Fumarate lyase family A3L01_05325 cee7f53e9212a62e06a1394f3c064992 451 PRINTS PR00149 Fumarate lyase superfamily signature 272 288 5.9E-27 T 23-10-2018 IPR000362 Fumarate lyase family A3L01_05325 cee7f53e9212a62e06a1394f3c064992 451 Gene3D G3DSA:1.20.200.10 101 359 1.3E-95 T 23-10-2018 A3L01_05325 cee7f53e9212a62e06a1394f3c064992 451 SUPERFAMILY SSF48557 4 443 2.2E-134 T 23-10-2018 IPR008948 L-Aspartase-like GO:0003824 A3L01_07180 7f6e9b0b12a346cd9cd052860163be3f 648 Pfam PF12838 4Fe-4S dicluster domain 593 639 3.7E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_07180 7f6e9b0b12a346cd9cd052860163be3f 648 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 28 210 1.6E-15 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L01_07180 7f6e9b0b12a346cd9cd052860163be3f 648 SUPERFAMILY SSF52922 249 355 3.77E-7 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L01_07180 7f6e9b0b12a346cd9cd052860163be3f 648 Gene3D G3DSA:3.40.50.970 7 195 3.2E-53 T 23-10-2018 A3L01_07180 7f6e9b0b12a346cd9cd052860163be3f 648 SUPERFAMILY SSF54862 584 640 2.73E-14 T 23-10-2018 A3L01_07180 7f6e9b0b12a346cd9cd052860163be3f 648 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 16 640 7.7E-273 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A3L01_07180 7f6e9b0b12a346cd9cd052860163be3f 648 Gene3D G3DSA:3.40.50.970 389 570 1.2E-22 T 23-10-2018 A3L01_07180 7f6e9b0b12a346cd9cd052860163be3f 648 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 625 636 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_07180 7f6e9b0b12a346cd9cd052860163be3f 648 PIRSF PIRSF006439 5 647 2.2E-261 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A3L01_07180 7f6e9b0b12a346cd9cd052860163be3f 648 Gene3D G3DSA:3.30.70.20 586 642 7.0E-10 T 23-10-2018 A3L01_07180 7f6e9b0b12a346cd9cd052860163be3f 648 SUPERFAMILY SSF52518 14 245 4.05E-56 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L01_07180 7f6e9b0b12a346cd9cd052860163be3f 648 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 410 564 1.9E-29 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L01_07180 7f6e9b0b12a346cd9cd052860163be3f 648 SUPERFAMILY SSF52518 380 602 5.59E-30 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L01_06120 98978b9b9d01a90636ad2ef2f1c4f055 218 SUPERFAMILY SSF89550 6 214 1.05E-34 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L01_06120 98978b9b9d01a90636ad2ef2f1c4f055 218 SMART SM00481 6 78 1.7E-10 T 23-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A3L01_06120 98978b9b9d01a90636ad2ef2f1c4f055 218 Pfam PF02811 PHP domain 7 111 1.1E-7 T 23-10-2018 IPR004013 PHP domain GO:0003824 A3L01_06120 98978b9b9d01a90636ad2ef2f1c4f055 218 Gene3D G3DSA:3.20.20.140 1 216 9.2E-45 T 23-10-2018 A3L01_06875 b3a048298b501285d63ec57912971503 382 Gene3D G3DSA:3.30.360.10 216 319 3.5E-133 T 23-10-2018 A3L01_06875 b3a048298b501285d63ec57912971503 382 PIRSF PIRSF015578 1 379 2.1E-95 T 23-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A3L01_06875 b3a048298b501285d63ec57912971503 382 Pfam PF01658 Myo-inositol-1-phosphate synthase 212 317 5.3E-20 T 23-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A3L01_06875 b3a048298b501285d63ec57912971503 382 Gene3D G3DSA:3.40.50.720 3 354 3.5E-133 T 23-10-2018 A3L01_06875 b3a048298b501285d63ec57912971503 382 SUPERFAMILY SSF55347 211 316 1.44E-28 T 23-10-2018 A3L01_06875 b3a048298b501285d63ec57912971503 382 Pfam PF07994 Myo-inositol-1-phosphate synthase 116 211 5.8E-10 T 23-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A3L01_06875 b3a048298b501285d63ec57912971503 382 SUPERFAMILY SSF51735 1 378 1.65E-72 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_04630 5dea09db116b0dcf57e3212891133cc6 121 ProDom PD005579 INITIATION FACTOR TRANSLATION 1A BIOSYNTHESIS EUKARYOTIC EIF-1A AIF-1A EIF-4C 1A 52 109 3.0E-26 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A3L01_04630 5dea09db116b0dcf57e3212891133cc6 121 SMART SM00652 27 110 1.0E-42 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A3L01_04630 5dea09db116b0dcf57e3212891133cc6 121 Pfam PF01176 Translation initiation factor 1A / IF-1 31 94 1.9E-20 T 23-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 A3L01_04630 5dea09db116b0dcf57e3212891133cc6 121 Hamap MF_00216 Translation initiation factor 1A [eif1a]. 16 110 27.947 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A3L01_04630 5dea09db116b0dcf57e3212891133cc6 121 TIGRFAM TIGR00523 eIF-1A: translation initiation factor eIF-1A 17 109 1.9E-34 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A3L01_04630 5dea09db116b0dcf57e3212891133cc6 121 ProSitePatterns PS01262 Eukaryotic initiation factor 1A signature. 40 62 - T 23-10-2018 IPR018104 Translation initiation factor 1A (eIF-1A), conserved site GO:0003743|GO:0006413 A3L01_04630 5dea09db116b0dcf57e3212891133cc6 121 SUPERFAMILY SSF50249 6 113 8.85E-32 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_04630 5dea09db116b0dcf57e3212891133cc6 121 Gene3D G3DSA:2.40.50.140 10 121 2.8E-40 T 23-10-2018 A3L01_06650 a507c2fb257db47e8d26bc86bf94fd9d 128 SUPERFAMILY SSF141322 63 125 7.98E-10 T 23-10-2018 A3L01_06650 a507c2fb257db47e8d26bc86bf94fd9d 128 Gene3D G3DSA:2.40.50.140 65 128 2.6E-17 T 23-10-2018 A3L01_06650 a507c2fb257db47e8d26bc86bf94fd9d 128 Pfam PF01957 NfeD-like C-terminal, partner-binding 17 125 2.8E-14 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain A3L01_09095 a9aed3f80bf236a98d410ae04ce25d66 126 Pfam PF04322 Protein of unknown function (DUF473) 1 114 3.1E-33 T 23-10-2018 IPR007417 Protein of unknown function DUF473 A3L01_09095 a9aed3f80bf236a98d410ae04ce25d66 126 ProDom PD020987 PF0014 UNCHARACTERIZED AF1250 PH0127 MJ0105 MA4414 ARCHAEAL 1 103 2.0E-34 T 23-10-2018 IPR007417 Protein of unknown function DUF473 A3L01_02295 d223ee677a70b51ff4c8415a086d4225 522 SMART SM00490 274 351 1.1E-10 T 23-10-2018 IPR001650 Helicase, C-terminal A3L01_02295 d223ee677a70b51ff4c8415a086d4225 522 Pfam PF00271 Helicase conserved C-terminal domain 248 351 5.0E-9 T 23-10-2018 IPR001650 Helicase, C-terminal A3L01_02295 d223ee677a70b51ff4c8415a086d4225 522 Gene3D G3DSA:3.40.50.300 224 386 3.4E-16 T 23-10-2018 A3L01_02295 d223ee677a70b51ff4c8415a086d4225 522 Gene3D G3DSA:3.40.50.300 20 214 2.7E-13 T 23-10-2018 A3L01_02295 d223ee677a70b51ff4c8415a086d4225 522 SMART SM00487 17 229 6.8E-12 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L01_02295 d223ee677a70b51ff4c8415a086d4225 522 SUPERFAMILY SSF52540 37 360 4.44E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_02295 d223ee677a70b51ff4c8415a086d4225 522 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 39 382 5.9E-87 T 23-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core A3L01_02295 d223ee677a70b51ff4c8415a086d4225 522 Pfam PF00270 DEAD/DEAH box helicase 40 198 2.9E-8 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L01_04715 c1a131445646c4eaef96f22905c55ad6 751 SUPERFAMILY SSF52402 476 608 5.19E-23 T 23-10-2018 A3L01_04715 c1a131445646c4eaef96f22905c55ad6 751 Gene3D G3DSA:1.20.1740.10 9 469 1.4E-100 T 23-10-2018 A3L01_04715 c1a131445646c4eaef96f22905c55ad6 751 PRINTS PR01438 Universal stress protein signature 566 578 1.1E-6 T 23-10-2018 IPR006015 Universal stress protein A A3L01_04715 c1a131445646c4eaef96f22905c55ad6 751 PRINTS PR01438 Universal stress protein signature 584 606 1.1E-6 T 23-10-2018 IPR006015 Universal stress protein A A3L01_04715 c1a131445646c4eaef96f22905c55ad6 751 Pfam PF00582 Universal stress protein family 650 733 4.9E-9 T 23-10-2018 IPR006016 UspA A3L01_04715 c1a131445646c4eaef96f22905c55ad6 751 Pfam PF00582 Universal stress protein family 476 606 2.5E-20 T 23-10-2018 IPR006016 UspA A3L01_04715 c1a131445646c4eaef96f22905c55ad6 751 Pfam PF13520 Amino acid permease 14 434 5.2E-50 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A3L01_04715 c1a131445646c4eaef96f22905c55ad6 751 Gene3D G3DSA:3.40.50.620 613 734 4.1E-13 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_04715 c1a131445646c4eaef96f22905c55ad6 751 SUPERFAMILY SSF52402 616 733 1.0E-15 T 23-10-2018 A3L01_04715 c1a131445646c4eaef96f22905c55ad6 751 Gene3D G3DSA:3.40.50.620 475 606 7.6E-21 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_01065 568079a158e91c6c9106769e74f385e4 66 Pfam PF00831 Ribosomal L29 protein 4 61 4.4E-18 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01065 568079a158e91c6c9106769e74f385e4 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 61 2.6E-20 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01065 568079a158e91c6c9106769e74f385e4 66 Gene3D G3DSA:1.10.287.310 1 66 3.8E-20 T 23-10-2018 A3L01_01065 568079a158e91c6c9106769e74f385e4 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 40 54 - T 23-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01065 568079a158e91c6c9106769e74f385e4 66 SUPERFAMILY SSF46561 1 61 1.07E-16 T 23-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01065 568079a158e91c6c9106769e74f385e4 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 61 16.07 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_07645 6f64c529d1ef7d77d6633f6da67d634c 398 Hamap MF_00553 Proteasome-activating nucleotidase [pan]. 2 397 47.252 T 23-10-2018 IPR023501 Proteasome-activating nucleotidase PAN A3L01_07645 6f64c529d1ef7d77d6633f6da67d634c 398 Gene3D G3DSA:3.40.50.300 129 309 4.4E-71 T 23-10-2018 A3L01_07645 6f64c529d1ef7d77d6633f6da67d634c 398 TIGRFAM TIGR01242 26Sp45: 26S proteasome subunit P45 family 19 379 1.3E-199 T 23-10-2018 IPR005937 26S proteasome regulatory subunit P45-like GO:0005737|GO:0016787|GO:0030163 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L01_07645 6f64c529d1ef7d77d6633f6da67d634c 398 Pfam PF16450 Proteasomal ATPase OB/ID domain 65 122 1.4E-7 T 23-10-2018 IPR032501 Proteasomal ATPase, OB/ID domain A3L01_07645 6f64c529d1ef7d77d6633f6da67d634c 398 Gene3D G3DSA:1.10.8.60 310 381 1.7E-29 T 23-10-2018 A3L01_07645 6f64c529d1ef7d77d6633f6da67d634c 398 ProSitePatterns PS00674 AAA-protein family signature. 279 297 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L01_07645 6f64c529d1ef7d77d6633f6da67d634c 398 Gene3D G3DSA:2.40.50.140 25 128 1.2E-25 T 23-10-2018 A3L01_07645 6f64c529d1ef7d77d6633f6da67d634c 398 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 176 309 7.2E-44 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L01_07645 6f64c529d1ef7d77d6633f6da67d634c 398 SUPERFAMILY SSF52540 134 386 3.43E-72 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_07645 6f64c529d1ef7d77d6633f6da67d634c 398 SMART SM00382 172 311 3.9E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_05490 68355bf1b86b19448bb6656a11d124f2 428 Pfam PF13173 AAA domain 32 163 5.1E-36 T 23-10-2018 A3L01_05490 68355bf1b86b19448bb6656a11d124f2 428 Pfam PF13635 Domain of unknown function (DUF4143) 247 371 2.9E-8 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 A3L01_05490 68355bf1b86b19448bb6656a11d124f2 428 SUPERFAMILY SSF52540 32 197 2.09E-16 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_01050 14496c5ff85efe441aa33f829da02721 133 PRINTS PR00975 Ribosomal protein S19 family signature 66 85 2.6E-19 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01050 14496c5ff85efe441aa33f829da02721 133 PRINTS PR00975 Ribosomal protein S19 family signature 86 98 2.6E-19 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01050 14496c5ff85efe441aa33f829da02721 133 PRINTS PR00975 Ribosomal protein S19 family signature 98 113 2.6E-19 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01050 14496c5ff85efe441aa33f829da02721 133 TIGRFAM TIGR01025 uS19_arch: ribosomal protein uS19 4 133 2.9E-65 T 23-10-2018 IPR005713 Ribosomal protein S19A/S15e GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01050 14496c5ff85efe441aa33f829da02721 133 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 35 117 6.7E-27 T 23-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 A3L01_01050 14496c5ff85efe441aa33f829da02721 133 SUPERFAMILY SSF54570 34 117 2.35E-31 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01050 14496c5ff85efe441aa33f829da02721 133 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 33 122 25.91 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01050 14496c5ff85efe441aa33f829da02721 133 ProSitePatterns PS00323 Ribosomal protein S19 signature. 86 110 - T 23-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01050 14496c5ff85efe441aa33f829da02721 133 Gene3D G3DSA:3.30.860.20 2 133 7.8E-54 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01050 14496c5ff85efe441aa33f829da02721 133 Pfam PF00203 Ribosomal protein S19 35 116 4.7E-36 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01050 14496c5ff85efe441aa33f829da02721 133 PIRSF PIRSF002144 1 133 1.2E-40 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_08295 0ce9e369cd160b1f3f344f26ccb4f63a 195 Hamap MF_00582 UPF0215 protein . 9 189 34.316 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A3L01_08295 0ce9e369cd160b1f3f344f26ccb4f63a 195 ProDom PD016744 UPF0215 ST0304 TK2033 MA4269 PAE0952 SSO0256 NEQ431 MK0057 PTO0905 TV0037 72 184 3.0E-43 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A3L01_08295 0ce9e369cd160b1f3f344f26ccb4f63a 195 Gene3D G3DSA:3.30.2170.10 3 195 4.2E-61 T 23-10-2018 A3L01_08295 0ce9e369cd160b1f3f344f26ccb4f63a 195 PIRSF PIRSF006380 1 195 5.9E-70 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A3L01_08295 0ce9e369cd160b1f3f344f26ccb4f63a 195 Pfam PF01949 Protein of unknown function DUF99 8 188 1.5E-64 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A3L01_03420 3fa2928fa896f1e8e15f267a058519d5 263 Gene3D G3DSA:3.40.50.700 3 163 2.4E-42 T 23-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily A3L01_03420 3fa2928fa896f1e8e15f267a058519d5 263 SUPERFAMILY SSF56770 3 210 4.32E-45 T 23-10-2018 A3L01_03420 3fa2928fa896f1e8e15f267a058519d5 263 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 15 149 8.7E-26 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_07445 9f1e612960bc4fcb91481432bfb4964b 225 Hamap MF_01220_A Uridylate kinase [pyrH]. 1 225 34.891 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A3L01_07445 9f1e612960bc4fcb91481432bfb4964b 225 SUPERFAMILY SSF53633 1 224 1.07E-51 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L01_07445 9f1e612960bc4fcb91481432bfb4964b 225 Gene3D G3DSA:3.40.1160.10 1 225 2.9E-61 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L01_07445 9f1e612960bc4fcb91481432bfb4964b 225 PIRSF PIRSF005650 1 225 2.8E-61 T 23-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A3L01_07445 9f1e612960bc4fcb91481432bfb4964b 225 TIGRFAM TIGR02076 pyrH_arch: putative uridylate kinase 3 224 3.7E-87 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A3L01_07445 9f1e612960bc4fcb91481432bfb4964b 225 Pfam PF00696 Amino acid kinase family 1 202 7.7E-35 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 Pfam PF01588 Putative tRNA binding domain 646 737 1.0E-31 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 SUPERFAMILY SSF47323 397 585 1.74E-46 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 Gene3D G3DSA:2.40.50.140 634 740 2.1E-43 T 23-10-2018 A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 Hamap MF_00098 Methionine--tRNA ligase [metG]. 2 559 42.788 T 23-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 Gene3D G3DSA:2.170.220.10 98 251 1.0E-143 T 23-10-2018 A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 548 2.3E-176 T 23-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 Pfam PF09334 tRNA synthetases class I (M) 4 407 6.4E-160 T 23-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 SUPERFAMILY SSF57770 139 173 1.02E-10 T 23-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 SUPERFAMILY SSF52374 3 394 1.63E-106 T 23-10-2018 A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 SUPERFAMILY SSF50249 639 739 7.35E-37 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 Gene3D G3DSA:1.10.730.10 397 547 6.0E-104 T 23-10-2018 A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 Gene3D G3DSA:3.40.50.620 5 315 1.0E-143 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 Pfam PF08264 Anticodon-binding domain of tRNA 429 520 1.0E-12 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 Gene3D G3DSA:1.10.730.10 340 580 6.0E-104 T 23-10-2018 A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 614 740 1.9E-38 T 23-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 7.1E-33 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 PRINTS PR01041 Methionyl-tRNA synthetase signature 293 308 7.1E-33 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 7.1E-33 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 PRINTS PR01041 Methionyl-tRNA synthetase signature 395 406 7.1E-33 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 7.1E-33 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 PRINTS PR01041 Methionyl-tRNA synthetase signature 251 262 7.1E-33 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L01_03605 aca319fa8bb14709ed300795af034f2a 740 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_01345 77ca50ddcb7c2deea8be87ecaf88b8ca 267 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 48 88 - T 23-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 A3L01_01345 77ca50ddcb7c2deea8be87ecaf88b8ca 267 Pfam PF01048 Phosphorylase superfamily 3 246 6.0E-55 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A3L01_01345 77ca50ddcb7c2deea8be87ecaf88b8ca 267 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 4 246 8.6E-95 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A3L01_01345 77ca50ddcb7c2deea8be87ecaf88b8ca 267 Gene3D G3DSA:3.40.50.1580 1 266 7.4E-100 T 23-10-2018 A3L01_01345 77ca50ddcb7c2deea8be87ecaf88b8ca 267 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 266 43.431 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A3L01_01345 77ca50ddcb7c2deea8be87ecaf88b8ca 267 SUPERFAMILY SSF53167 1 264 1.7E-94 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A3L01_07875 b8535d812abbb26890c790e5e7f3ee16 376 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 57 349 7.6E-70 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L01_07875 b8535d812abbb26890c790e5e7f3ee16 376 SUPERFAMILY SSF53686 5 355 2.1E-85 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L01_07875 b8535d812abbb26890c790e5e7f3ee16 376 Gene3D G3DSA:3.40.50.1100 91 186 7.4E-102 T 23-10-2018 A3L01_07875 b8535d812abbb26890c790e5e7f3ee16 376 Gene3D G3DSA:3.40.50.1100 43 354 7.4E-102 T 23-10-2018 A3L01_07875 b8535d812abbb26890c790e5e7f3ee16 376 TIGRFAM TIGR00260 thrC: threonine synthase 50 351 3.7E-52 T 23-10-2018 IPR004450 Threonine synthase-like A3L01_00225 9e74c5be156bea8a7f90ad288ca7720d 51 Pfam PF01599 Ribosomal protein S27a 5 46 6.6E-23 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L01_00225 9e74c5be156bea8a7f90ad288ca7720d 51 SUPERFAMILY SSF57829 4 50 1.83E-21 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L01_00225 9e74c5be156bea8a7f90ad288ca7720d 51 Gene3D G3DSA:2.20.25.660 2 49 1.0E-19 T 23-10-2018 IPR038582 S27a-like superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L01_00225 9e74c5be156bea8a7f90ad288ca7720d 51 Hamap MF_00777 30S ribosomal protein S27ae [rps27ae]. 4 49 19.814 T 23-10-2018 IPR022845 Ribosomal protein S27ae A3L01_00225 9e74c5be156bea8a7f90ad288ca7720d 51 SMART SM01402 4 46 3.5E-25 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L01_04590 77435550cdd121aa09e9393f2b26c32f 267 Hamap MF_01527_A GTP cyclohydrolase FolE2 [folE2]. 1 267 26.697 T 23-10-2018 IPR022840 GTP cyclohydrolase MptA GO:0003933 KEGG: 00790+3.5.4.39|MetaCyc: PWY-6797|MetaCyc: PWY-7853 A3L01_04590 77435550cdd121aa09e9393f2b26c32f 267 Gene3D G3DSA:3.10.270.10 1 266 1.0E-67 T 23-10-2018 A3L01_04590 77435550cdd121aa09e9393f2b26c32f 267 Pfam PF02649 Type I GTP cyclohydrolase folE2 3 263 1.7E-65 T 23-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 A3L01_02510 d2285951caf1aeafa6013567f143f86d 391 Pfam PF00571 CBS domain 211 261 1.7E-10 T 23-10-2018 IPR000644 CBS domain A3L01_02510 d2285951caf1aeafa6013567f143f86d 391 Pfam PF00571 CBS domain 70 123 2.4E-6 T 23-10-2018 IPR000644 CBS domain A3L01_02510 d2285951caf1aeafa6013567f143f86d 391 Pfam PF00571 CBS domain 132 183 1.2E-17 T 23-10-2018 IPR000644 CBS domain A3L01_02510 d2285951caf1aeafa6013567f143f86d 391 SMART SM00116 217 265 8.9E-9 T 23-10-2018 IPR000644 CBS domain A3L01_02510 d2285951caf1aeafa6013567f143f86d 391 SMART SM00116 75 123 0.51 T 23-10-2018 IPR000644 CBS domain A3L01_02510 d2285951caf1aeafa6013567f143f86d 391 SMART SM00116 139 187 4.1E-10 T 23-10-2018 IPR000644 CBS domain A3L01_02510 d2285951caf1aeafa6013567f143f86d 391 Gene3D G3DSA:3.10.580.10 207 302 2.7E-14 T 23-10-2018 A3L01_02510 d2285951caf1aeafa6013567f143f86d 391 Gene3D G3DSA:3.10.580.10 124 206 1.1E-19 T 23-10-2018 A3L01_02510 d2285951caf1aeafa6013567f143f86d 391 Gene3D G3DSA:3.10.580.10 4 123 2.9E-16 T 23-10-2018 A3L01_02510 d2285951caf1aeafa6013567f143f86d 391 PIRSF PIRSF036983 2 391 1.8E-139 T 23-10-2018 IPR014651 Uncharacterised conserved protein, 2xCBS, MJ1404 type A3L01_02510 d2285951caf1aeafa6013567f143f86d 391 SUPERFAMILY SSF54631 4 124 4.93E-18 T 23-10-2018 A3L01_02510 d2285951caf1aeafa6013567f143f86d 391 SUPERFAMILY SSF54631 124 261 5.9E-35 T 23-10-2018 A3L01_04785 1612f2add4f5ccd3c312dba5ef1673b7 270 Pfam PF05552 Conserved TM helix 17 48 5.3E-7 T 23-10-2018 IPR008910 Conserved TM helix A3L01_04785 1612f2add4f5ccd3c312dba5ef1673b7 270 Gene3D G3DSA:2.30.30.60 117 166 8.4E-15 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily A3L01_04785 1612f2add4f5ccd3c312dba5ef1673b7 270 SUPERFAMILY SSF50182 101 167 5.89E-15 T 23-10-2018 IPR010920 LSM domain superfamily A3L01_04785 1612f2add4f5ccd3c312dba5ef1673b7 270 Gene3D G3DSA:3.30.70.100 167 261 5.9E-30 T 23-10-2018 A3L01_04785 1612f2add4f5ccd3c312dba5ef1673b7 270 SUPERFAMILY SSF82689 168 266 3.79E-33 T 23-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A3L01_04785 1612f2add4f5ccd3c312dba5ef1673b7 270 SUPERFAMILY SSF82861 16 100 1.07E-12 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A3L01_04785 1612f2add4f5ccd3c312dba5ef1673b7 270 Pfam PF00924 Mechanosensitive ion channel 59 256 4.2E-50 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A3L01_02465 0d2adbaee22ec7f24b84becbdef35c33 533 Hamap MF_01227 CTP synthase [pyrG]. 2 530 53.182 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A3L01_02465 0d2adbaee22ec7f24b84becbdef35c33 533 Gene3D G3DSA:3.40.50.300 1 283 2.3E-139 T 23-10-2018 A3L01_02465 0d2adbaee22ec7f24b84becbdef35c33 533 Pfam PF00117 Glutamine amidotransferase class-I 300 524 3.8E-58 T 23-10-2018 IPR017926 Glutamine amidotransferase A3L01_02465 0d2adbaee22ec7f24b84becbdef35c33 533 SUPERFAMILY SSF52317 288 529 6.8E-80 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_02465 0d2adbaee22ec7f24b84becbdef35c33 533 Gene3D G3DSA:3.40.50.880 284 532 2.2E-107 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_02465 0d2adbaee22ec7f24b84becbdef35c33 533 Pfam PF06418 CTP synthase N-terminus 3 265 1.9E-127 T 23-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A3L01_02465 0d2adbaee22ec7f24b84becbdef35c33 533 TIGRFAM TIGR00337 PyrG: CTP synthase 1 525 3.3E-251 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A3L01_02465 0d2adbaee22ec7f24b84becbdef35c33 533 SUPERFAMILY SSF52540 2 265 1.75E-121 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_01710 f19596effb48178fbaedbcf6551f2a3f 139 Gene3D G3DSA:3.30.2320.50 2 130 4.9E-26 T 23-10-2018 A3L01_01710 f19596effb48178fbaedbcf6551f2a3f 139 PIRSF PIRSF004761 1 137 5.7E-33 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 A3L01_01710 f19596effb48178fbaedbcf6551f2a3f 139 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 23-10-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site A3L01_01710 f19596effb48178fbaedbcf6551f2a3f 139 Gene3D G3DSA:2.20.28.10 69 123 4.9E-26 T 23-10-2018 A3L01_01710 f19596effb48178fbaedbcf6551f2a3f 139 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 134 20.352 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 A3L01_01710 f19596effb48178fbaedbcf6551f2a3f 139 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 132 1.2E-25 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 A3L01_04645 7c4decc6cb1eef67bbe0ca4c852d359f 230 Hamap MF_00052_A Ribonuclease HII [rnhB]. 2 206 37.95 T 23-10-2018 IPR020787 Ribonuclease HII, archaea GO:0004523|GO:0005737|GO:0006401|GO:0030145 A3L01_04645 7c4decc6cb1eef67bbe0ca4c852d359f 230 Pfam PF01351 Ribonuclease HII 4 200 4.8E-51 T 23-10-2018 IPR024567 Ribonuclease HII/HIII domain A3L01_04645 7c4decc6cb1eef67bbe0ca4c852d359f 230 Gene3D G3DSA:1.10.10.460 162 208 2.6E-24 T 23-10-2018 IPR023160 Ribonuclease HII, helix-loop-helix cap domain superfamily GO:0004523 A3L01_04645 7c4decc6cb1eef67bbe0ca4c852d359f 230 Gene3D G3DSA:3.30.420.10 2 161 2.1E-59 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A3L01_04645 7c4decc6cb1eef67bbe0ca4c852d359f 230 SUPERFAMILY SSF53098 3 209 1.97E-58 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily A3L01_04645 7c4decc6cb1eef67bbe0ca4c852d359f 230 TIGRFAM TIGR00729 TIGR00729: ribonuclease HII 4 205 1.3E-76 T 23-10-2018 IPR004649 Ribonuclease H2, subunit A GO:0004523|GO:0016070 A3L01_09180 a12b8f23286f748e05eac94c61cc9bdb 469 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 161 297 1.3E-56 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L01_09180 a12b8f23286f748e05eac94c61cc9bdb 469 Pfam PF13380 CoA binding domain 13 139 9.8E-23 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L01_09180 a12b8f23286f748e05eac94c61cc9bdb 469 SUPERFAMILY SSF52210 304 463 2.88E-35 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L01_09180 a12b8f23286f748e05eac94c61cc9bdb 469 Gene3D G3DSA:3.40.50.720 4 134 1.3E-43 T 23-10-2018 A3L01_09180 a12b8f23286f748e05eac94c61cc9bdb 469 SUPERFAMILY SSF51735 6 135 3.09E-36 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_09180 a12b8f23286f748e05eac94c61cc9bdb 469 SUPERFAMILY SSF52210 136 298 7.33E-42 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L01_09180 a12b8f23286f748e05eac94c61cc9bdb 469 Gene3D G3DSA:3.40.50.261 136 300 2.1E-59 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L01_09180 a12b8f23286f748e05eac94c61cc9bdb 469 SMART SM00881 9 107 2.3E-38 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L01_09180 a12b8f23286f748e05eac94c61cc9bdb 469 Gene3D G3DSA:3.40.50.261 302 466 1.1E-44 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L01_08360 3d66b136d45bcd7e7011b3e24c0a54d1 420 Gene3D G3DSA:3.50.50.60 4 403 1.9E-139 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_08360 3d66b136d45bcd7e7011b3e24c0a54d1 420 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 70 8.8E-14 T 23-10-2018 A3L01_08360 3d66b136d45bcd7e7011b3e24c0a54d1 420 SUPERFAMILY SSF51905 1 392 9.79E-39 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_08360 3d66b136d45bcd7e7011b3e24c0a54d1 420 PRINTS PR00419 Adrenodoxin reductase family signature 25 38 1.9E-5 T 23-10-2018 A3L01_08360 3d66b136d45bcd7e7011b3e24c0a54d1 420 PRINTS PR00419 Adrenodoxin reductase family signature 2 24 1.9E-5 T 23-10-2018 A3L01_08360 3d66b136d45bcd7e7011b3e24c0a54d1 420 Gene3D G3DSA:3.90.660.50 83 359 1.9E-139 T 23-10-2018 A3L01_01090 7498777bf9c64a25ba52da5c8216986f 121 Pfam PF00467 KOW motif 48 79 1.4E-10 T 23-10-2018 IPR005824 KOW A3L01_01090 7498777bf9c64a25ba52da5c8216986f 121 Hamap MF_01326_A 50S ribosomal protein L24 [rplX]. 5 118 31.703 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01090 7498777bf9c64a25ba52da5c8216986f 121 TIGRFAM TIGR01080 rplX_A_E: ribosomal protein uL24 6 120 9.5E-57 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01090 7498777bf9c64a25ba52da5c8216986f 121 SUPERFAMILY SSF50104 6 116 5.16E-38 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L01_01090 7498777bf9c64a25ba52da5c8216986f 121 Gene3D G3DSA:2.30.30.30 1 121 2.2E-51 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L01_01090 7498777bf9c64a25ba52da5c8216986f 121 ProSitePatterns PS01108 Ribosomal protein L24 signature. 49 66 - T 23-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01090 7498777bf9c64a25ba52da5c8216986f 121 Pfam PF16906 Ribosomal proteins L26 eukaryotic, L24P archaeal 5 119 1.1E-33 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01090 7498777bf9c64a25ba52da5c8216986f 121 SMART SM00739 45 72 1.7E-7 T 23-10-2018 IPR005824 KOW A3L01_01270 a8362df54c504c1a5bfcd9a2bb87de67 52 Hamap MF_00788 50S ribosomal protein L40e [rpl40e]. 2 47 19.565 T 23-10-2018 IPR023657 Ribosomal protein L40e, archaeal GO:0003735|GO:0005840|GO:0006412 A3L01_01270 a8362df54c504c1a5bfcd9a2bb87de67 52 SMART SM01377 1 46 3.5E-8 T 23-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L01_01270 a8362df54c504c1a5bfcd9a2bb87de67 52 Gene3D G3DSA:2.20.28.70 1 49 1.1E-18 T 23-10-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L01_01270 a8362df54c504c1a5bfcd9a2bb87de67 52 SUPERFAMILY SSF57829 2 46 8.24E-16 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L01_05495 615986c7a769cbb94bf001c5e5307b9e 316 Gene3D G3DSA:1.10.10.10 240 316 1.1E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_05495 615986c7a769cbb94bf001c5e5307b9e 316 Pfam PF12802 MarR family 263 305 3.4E-9 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A3L01_05495 615986c7a769cbb94bf001c5e5307b9e 316 SUPERFAMILY SSF46785 262 315 7.86E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_02720 264ec5e447532f34a009956c6fdd16ce 386 Gene3D G3DSA:3.30.70.2510 162 275 4.5E-31 T 23-10-2018 A3L01_02720 264ec5e447532f34a009956c6fdd16ce 386 TIGRFAM TIGR01213 pseudo_Pus10arc: tRNA pseudouridine(54/55) synthase 8 385 3.7E-146 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 A3L01_02720 264ec5e447532f34a009956c6fdd16ce 386 Pfam PF02926 THUMP domain 50 162 6.2E-10 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L01_02720 264ec5e447532f34a009956c6fdd16ce 386 Gene3D G3DSA:3.30.70.3190 276 384 4.2E-28 T 23-10-2018 A3L01_02720 264ec5e447532f34a009956c6fdd16ce 386 SUPERFAMILY SSF55120 271 383 1.37E-11 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L01_02720 264ec5e447532f34a009956c6fdd16ce 386 Hamap MF_01893 tRNA pseudouridine synthase Pus10 [pus10]. 7 385 51.372 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 A3L01_06220 c8e04b10a4b8056f80757cac03d7bcf4 837 SUPERFAMILY SSF52540 540 818 4.67E-79 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06220 c8e04b10a4b8056f80757cac03d7bcf4 837 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 13 822 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 A3L01_06220 c8e04b10a4b8056f80757cac03d7bcf4 837 Gene3D G3DSA:2.40.40.20 8 98 7.2E-33 T 23-10-2018 A3L01_06220 c8e04b10a4b8056f80757cac03d7bcf4 837 SMART SM00382 244 380 8.4E-26 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_06220 c8e04b10a4b8056f80757cac03d7bcf4 837 SMART SM00382 579 715 7.2E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_06220 c8e04b10a4b8056f80757cac03d7bcf4 837 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 118 200 2.1E-14 T 23-10-2018 IPR004201 CDC48, domain 2 A3L01_06220 c8e04b10a4b8056f80757cac03d7bcf4 837 Gene3D G3DSA:1.10.8.60 714 822 6.6E-31 T 23-10-2018 A3L01_06220 c8e04b10a4b8056f80757cac03d7bcf4 837 Gene3D G3DSA:1.10.8.60 454 536 2.5E-16 T 23-10-2018 A3L01_06220 c8e04b10a4b8056f80757cac03d7bcf4 837 Gene3D G3DSA:1.10.8.60 379 402 1.4E-82 T 23-10-2018 A3L01_06220 c8e04b10a4b8056f80757cac03d7bcf4 837 SMART SM01072 116 200 4.0E-17 T 23-10-2018 IPR004201 CDC48, domain 2 A3L01_06220 c8e04b10a4b8056f80757cac03d7bcf4 837 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 14 98 2.3E-30 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A3L01_06220 c8e04b10a4b8056f80757cac03d7bcf4 837 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 248 377 8.5E-51 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L01_06220 c8e04b10a4b8056f80757cac03d7bcf4 837 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 583 712 1.0E-47 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L01_06220 c8e04b10a4b8056f80757cac03d7bcf4 837 ProSitePatterns PS00674 AAA-protein family signature. 683 701 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L01_06220 c8e04b10a4b8056f80757cac03d7bcf4 837 Gene3D G3DSA:3.40.50.300 206 378 1.4E-82 T 23-10-2018 A3L01_06220 c8e04b10a4b8056f80757cac03d7bcf4 837 ProSitePatterns PS00674 AAA-protein family signature. 348 366 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L01_06220 c8e04b10a4b8056f80757cac03d7bcf4 837 SMART SM01073 14 98 1.7E-37 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A3L01_06220 c8e04b10a4b8056f80757cac03d7bcf4 837 SUPERFAMILY SSF50692 11 96 2.4E-27 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L01_06220 c8e04b10a4b8056f80757cac03d7bcf4 837 SUPERFAMILY SSF52540 206 527 6.96E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06220 c8e04b10a4b8056f80757cac03d7bcf4 837 SUPERFAMILY SSF54585 98 213 1.08E-17 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily A3L01_06220 c8e04b10a4b8056f80757cac03d7bcf4 837 Gene3D G3DSA:3.40.50.300 537 712 1.4E-74 T 23-10-2018 A3L01_03995 de710307544bc5e735c462eaf6ad40fe 378 SUPERFAMILY SSF53335 4 375 6.17E-106 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_03995 de710307544bc5e735c462eaf6ad40fe 378 Gene3D G3DSA:3.30.56.70 318 377 4.8E-22 T 23-10-2018 A3L01_03995 de710307544bc5e735c462eaf6ad40fe 378 TIGRFAM TIGR00308 TRM1: N2,N2-dimethylguanosine tRNA methyltransferase 6 376 1.9E-96 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 A3L01_03995 de710307544bc5e735c462eaf6ad40fe 378 Hamap MF_00290 tRNA (guanine(26)-N(2))-dimethyltransferase [trm1]. 4 376 43.117 T 23-10-2018 IPR022923 tRNA (guanine(26)-N(2))-dimethyltransferase, archaeal and bacterial GO:0004809 MetaCyc: PWY-6829 A3L01_03995 de710307544bc5e735c462eaf6ad40fe 378 Gene3D G3DSA:3.40.50.150 1 317 1.2E-100 T 23-10-2018 A3L01_03995 de710307544bc5e735c462eaf6ad40fe 378 Pfam PF02005 N2,N2-dimethylguanosine tRNA methyltransferase 9 375 1.1E-112 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 A3L01_04485 d43c76fef3a72d85a9be9adacd58d523 59 SUPERFAMILY SSF47113 5 59 4.37E-6 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L01_05215 ca3943d2cbf0f44ec765e46d515a3044 308 Gene3D G3DSA:3.90.25.10 168 301 6.5E-106 T 23-10-2018 A3L01_05215 ca3943d2cbf0f44ec765e46d515a3044 308 Gene3D G3DSA:3.40.50.720 8 289 6.5E-106 T 23-10-2018 A3L01_05215 ca3943d2cbf0f44ec765e46d515a3044 308 SUPERFAMILY SSF51735 1 305 6.62E-99 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_05215 ca3943d2cbf0f44ec765e46d515a3044 308 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 236 6.8E-62 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A3L01_03805 deed77adc34a1f01d7ad21afd58afe93 242 Pfam PF02195 ParB-like nuclease domain 22 92 4.2E-9 T 23-10-2018 IPR003115 ParB/Sulfiredoxin A3L01_03805 deed77adc34a1f01d7ad21afd58afe93 242 SMART SM00470 19 114 2.8E-13 T 23-10-2018 IPR003115 ParB/Sulfiredoxin A3L01_03805 deed77adc34a1f01d7ad21afd58afe93 242 SUPERFAMILY SSF110849 12 241 4.71E-62 T 23-10-2018 IPR036086 ParB/Sulfiredoxin superfamily A3L01_03805 deed77adc34a1f01d7ad21afd58afe93 242 Gene3D G3DSA:3.90.1530.10 17 238 1.8E-83 T 23-10-2018 A3L01_03805 deed77adc34a1f01d7ad21afd58afe93 242 Gene3D G3DSA:3.30.1760.10 98 227 1.8E-83 T 23-10-2018 IPR023098 ParB-like nuclease, C-terminal A3L01_07055 bfb989199bf9c89a059bb70835b2cc7b 287 SUPERFAMILY SSF63380 2 93 2.88E-15 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L01_07055 bfb989199bf9c89a059bb70835b2cc7b 287 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 221 256 1.1E-11 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L01_07055 bfb989199bf9c89a059bb70835b2cc7b 287 Gene3D G3DSA:3.40.50.80 100 211 9.4E-27 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L01_07055 bfb989199bf9c89a059bb70835b2cc7b 287 SUPERFAMILY SSF52343 89 256 2.97E-16 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L01_07055 bfb989199bf9c89a059bb70835b2cc7b 287 PIRSF PIRSF006816 1 263 4.7E-67 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L01_07055 bfb989199bf9c89a059bb70835b2cc7b 287 Gene3D G3DSA:2.40.30.10 1 92 1.6E-15 T 23-10-2018 A3L01_09380 4430254d18d6ce9f3d8370d3ef66643e 292 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 3 262 9.4E-114 T 23-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 A3L01_09380 4430254d18d6ce9f3d8370d3ef66643e 292 Pfam PF00483 Nucleotidyl transferase 5 264 1.7E-30 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L01_09380 4430254d18d6ce9f3d8370d3ef66643e 292 SUPERFAMILY SSF53448 3 270 3.62E-68 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_09380 4430254d18d6ce9f3d8370d3ef66643e 292 Gene3D G3DSA:3.90.550.10 1 290 4.1E-92 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_03490 922721762666f75aac1090f8564a02b5 487 SUPERFAMILY SSF64182 161 453 4.19E-56 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L01_03490 922721762666f75aac1090f8564a02b5 487 SUPERFAMILY SSF51735 1 139 6.19E-20 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_03490 922721762666f75aac1090f8564a02b5 487 Pfam PF01368 DHH family 164 315 5.8E-10 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A3L01_03490 922721762666f75aac1090f8564a02b5 487 Pfam PF02254 TrkA-N domain 3 106 7.1E-19 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A3L01_03490 922721762666f75aac1090f8564a02b5 487 Gene3D G3DSA:3.40.50.720 1 140 4.0E-21 T 23-10-2018 A3L01_03490 922721762666f75aac1090f8564a02b5 487 Pfam PF02272 DHHA1 domain 355 473 3.3E-14 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L01_03490 922721762666f75aac1090f8564a02b5 487 Gene3D G3DSA:3.90.1640.10 162 366 2.4E-27 T 23-10-2018 A3L01_02800 ac267b84a22c9551f3edfd58e1c308b7 421 SUPERFAMILY SSF89550 5 227 1.0E-13 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L01_02800 ac267b84a22c9551f3edfd58e1c308b7 421 TIGRFAM TIGR00375 TIGR00375: TIGR00375 family protein 5 380 7.2E-127 T 23-10-2018 IPR005287 Conserved hypothetical protein CHP00375 A3L01_02800 ac267b84a22c9551f3edfd58e1c308b7 421 Gene3D G3DSA:3.20.20.140 1 228 4.2E-14 T 23-10-2018 A3L01_08130 9c2af52b0d8f4ee54a9242f66b06b44e 238 Pfam PF00588 SpoU rRNA Methylase family 3 150 2.5E-32 T 23-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A3L01_08130 9c2af52b0d8f4ee54a9242f66b06b44e 238 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 1 225 4.4E-59 T 23-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 A3L01_08130 9c2af52b0d8f4ee54a9242f66b06b44e 238 SUPERFAMILY SSF75217 4 172 1.37E-31 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L01_08130 9c2af52b0d8f4ee54a9242f66b06b44e 238 PIRSF PIRSF004808 1 235 3.4E-71 T 23-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 A3L01_08130 9c2af52b0d8f4ee54a9242f66b06b44e 238 Gene3D G3DSA:3.40.1280.10 1 156 4.5E-47 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L01_03635 f9d7596aad8211ffd9932443d2c2da61 186 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 176 2.2E-34 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L01_03635 f9d7596aad8211ffd9932443d2c2da61 186 Gene3D G3DSA:3.40.920.10 1 185 4.3E-55 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L01_03635 f9d7596aad8211ffd9932443d2c2da61 186 SUPERFAMILY SSF53323 1 180 3.79E-41 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L01_03120 e8c06c0a6a7bfe4c97983f5f01c0c26d 358 Gene3D G3DSA:3.90.230.10 143 358 1.7E-38 T 23-10-2018 A3L01_03120 e8c06c0a6a7bfe4c97983f5f01c0c26d 358 Pfam PF01321 Creatinase/Prolidase N-terminal domain 11 142 3.0E-13 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 A3L01_03120 e8c06c0a6a7bfe4c97983f5f01c0c26d 358 Pfam PF00557 Metallopeptidase family M24 149 350 3.7E-28 T 23-10-2018 IPR000994 Peptidase M24 A3L01_03120 e8c06c0a6a7bfe4c97983f5f01c0c26d 358 SUPERFAMILY SSF53092 6 141 5.41E-23 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L01_03120 e8c06c0a6a7bfe4c97983f5f01c0c26d 358 Gene3D G3DSA:3.40.350.10 8 142 3.3E-20 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L01_03120 e8c06c0a6a7bfe4c97983f5f01c0c26d 358 SUPERFAMILY SSF55920 141 357 8.9E-40 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like A3L01_07695 ebdbbe4c1f1304d1423681ca0e3a00ee 526 Gene3D G3DSA:1.10.10.770 319 433 2.9E-37 T 23-10-2018 A3L01_07695 ebdbbe4c1f1304d1423681ca0e3a00ee 526 Pfam PF01921 tRNA synthetases class I (K) 3 362 2.8E-138 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A3L01_07695 ebdbbe4c1f1304d1423681ca0e3a00ee 526 Gene3D G3DSA:2.30.30.300 170 213 3.9E-110 T 23-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 A3L01_07695 ebdbbe4c1f1304d1423681ca0e3a00ee 526 Gene3D G3DSA:3.40.50.620 4 270 3.9E-110 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_07695 ebdbbe4c1f1304d1423681ca0e3a00ee 526 Gene3D G3DSA:1.10.10.860 271 318 2.3E-23 T 23-10-2018 A3L01_07695 ebdbbe4c1f1304d1423681ca0e3a00ee 526 Gene3D G3DSA:1.10.10.350 434 526 2.2E-26 T 23-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A3L01_07695 ebdbbe4c1f1304d1423681ca0e3a00ee 526 SUPERFAMILY SSF52374 3 319 3.07E-66 T 23-10-2018 A3L01_07695 ebdbbe4c1f1304d1423681ca0e3a00ee 526 SUPERFAMILY SSF48163 323 523 9.29E-49 T 23-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A3L01_07695 ebdbbe4c1f1304d1423681ca0e3a00ee 526 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 2 526 38.112 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A3L01_07695 ebdbbe4c1f1304d1423681ca0e3a00ee 526 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 2 523 8.2E-159 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A3L01_07695 ebdbbe4c1f1304d1423681ca0e3a00ee 526 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 30 39 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_04430 4a68ff7031830cd956362b65f3823b4b 591 SUPERFAMILY SSF52540 360 529 7.05E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_04430 4a68ff7031830cd956362b65f3823b4b 591 SUPERFAMILY SSF52540 96 285 3.52E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_04430 4a68ff7031830cd956362b65f3823b4b 591 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 1 32 1.2E-11 T 23-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain A3L01_04430 4a68ff7031830cd956362b65f3823b4b 591 Gene3D G3DSA:3.40.50.300 327 589 3.0E-66 T 23-10-2018 A3L01_04430 4a68ff7031830cd956362b65f3823b4b 591 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_04430 4a68ff7031830cd956362b65f3823b4b 591 Pfam PF00005 ABC transporter 96 238 5.1E-17 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_04430 4a68ff7031830cd956362b65f3823b4b 591 SUPERFAMILY SSF54862 4 124 1.95E-24 T 23-10-2018 A3L01_04430 4a68ff7031830cd956362b65f3823b4b 591 ProSitePatterns PS00211 ABC transporters family signature. 211 225 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_04430 4a68ff7031830cd956362b65f3823b4b 591 Pfam PF00037 4Fe-4S binding domain 44 67 4.3E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_04430 4a68ff7031830cd956362b65f3823b4b 591 PRINTS PR01868 ABC transporter family E signature 103 128 1.0E-62 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L01_04430 4a68ff7031830cd956362b65f3823b4b 591 PRINTS PR01868 ABC transporter family E signature 150 176 1.0E-62 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L01_04430 4a68ff7031830cd956362b65f3823b4b 591 PRINTS PR01868 ABC transporter family E signature 134 150 1.0E-62 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L01_04430 4a68ff7031830cd956362b65f3823b4b 591 PRINTS PR01868 ABC transporter family E signature 48 72 1.0E-62 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L01_04430 4a68ff7031830cd956362b65f3823b4b 591 PRINTS PR01868 ABC transporter family E signature 20 35 1.0E-62 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L01_04430 4a68ff7031830cd956362b65f3823b4b 591 PRINTS PR01868 ABC transporter family E signature 75 95 1.0E-62 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L01_04430 4a68ff7031830cd956362b65f3823b4b 591 SMART SM00382 363 531 2.1E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_04430 4a68ff7031830cd956362b65f3823b4b 591 SMART SM00382 98 286 3.5E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_04430 4a68ff7031830cd956362b65f3823b4b 591 Pfam PF00005 ABC transporter 361 482 8.0E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_04430 4a68ff7031830cd956362b65f3823b4b 591 Gene3D G3DSA:3.40.50.300 1 326 1.8E-102 T 23-10-2018 A3L01_02570 a0a97417b19e52a4418496b5faf0e20e 264 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 34 264 40.639 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A3L01_02570 a0a97417b19e52a4418496b5faf0e20e 264 SUPERFAMILY SSF64005 32 259 1.44E-88 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 A3L01_02570 a0a97417b19e52a4418496b5faf0e20e 264 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 209 226 - T 23-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 A3L01_02570 a0a97417b19e52a4418496b5faf0e20e 264 Gene3D G3DSA:3.40.1180.10 20 264 3.7E-103 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 A3L01_02570 a0a97417b19e52a4418496b5faf0e20e 264 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 34 263 2.0E-87 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A3L01_02570 a0a97417b19e52a4418496b5faf0e20e 264 Pfam PF01255 Putative undecaprenyl diphosphate synthase 41 263 8.3E-84 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A3L01_02670 09e8f879b0a02e9b75e8cda244f1b6cb 568 Gene3D G3DSA:3.30.56.10 279 348 8.1E-26 T 23-10-2018 A3L01_02670 09e8f879b0a02e9b75e8cda244f1b6cb 568 Pfam PF03484 tRNA synthetase B5 domain 284 348 4.9E-13 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A3L01_02670 09e8f879b0a02e9b75e8cda244f1b6cb 568 Gene3D G3DSA:3.30.56.10 1 80 2.3E-23 T 23-10-2018 A3L01_02670 09e8f879b0a02e9b75e8cda244f1b6cb 568 SMART SM00874 280 348 8.2E-19 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A3L01_02670 09e8f879b0a02e9b75e8cda244f1b6cb 568 SUPERFAMILY SSF46955 281 352 9.16E-16 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily A3L01_02670 09e8f879b0a02e9b75e8cda244f1b6cb 568 Pfam PF03483 B3/4 domain 119 244 3.8E-16 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A3L01_02670 09e8f879b0a02e9b75e8cda244f1b6cb 568 SUPERFAMILY SSF46955 5 81 4.85E-9 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily A3L01_02670 09e8f879b0a02e9b75e8cda244f1b6cb 568 TIGRFAM TIGR00471 pheT_arch: phenylalanine--tRNA ligase, beta subunit 1 557 3.6E-177 T 23-10-2018 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A3L01_02670 09e8f879b0a02e9b75e8cda244f1b6cb 568 Gene3D G3DSA:3.30.930.10 365 564 2.9E-52 T 23-10-2018 A3L01_02670 09e8f879b0a02e9b75e8cda244f1b6cb 568 Pfam PF01409 tRNA synthetases class II core domain (F) 331 555 9.2E-5 T 23-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 A3L01_02670 09e8f879b0a02e9b75e8cda244f1b6cb 568 SUPERFAMILY SSF55681 345 562 6.3E-45 T 23-10-2018 A3L01_02670 09e8f879b0a02e9b75e8cda244f1b6cb 568 SMART SM00873 100 259 1.1E-18 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A3L01_02670 09e8f879b0a02e9b75e8cda244f1b6cb 568 SUPERFAMILY SSF56037 142 257 1.75E-5 T 23-10-2018 A3L01_02670 09e8f879b0a02e9b75e8cda244f1b6cb 568 Hamap MF_00284 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 560 35.964 T 23-10-2018 IPR022918 Phenylalanine-tRNA ligase beta chain 2, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 A3L01_02670 09e8f879b0a02e9b75e8cda244f1b6cb 568 Gene3D G3DSA:3.50.40.10 81 278 2.3E-72 T 23-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 A3L01_00480 c0cbe34c4665ac58d39d9930e83bc8e3 209 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 177 9.5E-13 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L01_00480 c0cbe34c4665ac58d39d9930e83bc8e3 209 SUPERFAMILY SSF52540 2 182 3.64E-30 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_00480 c0cbe34c4665ac58d39d9930e83bc8e3 209 Pfam PF01926 50S ribosome-binding GTPase 2 129 2.0E-17 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_00480 c0cbe34c4665ac58d39d9930e83bc8e3 209 Gene3D G3DSA:3.40.50.300 1 187 2.7E-51 T 23-10-2018 A3L01_00480 c0cbe34c4665ac58d39d9930e83bc8e3 209 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 1 180 21.209 T 23-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 A3L01_02245 b8b90575c3b90e5c16e37480beb21acd 393 Hamap MF_01287 Digeranylgeranylglycerophospholipid reductase. 1 393 39.638 T 23-10-2018 IPR023590 Digeranylgeranylglycerophospholipid reductase GO:0016628|GO:0045550|GO:0046467|GO:0055114 KEGG: 00564+1.3.7.11|MetaCyc: PWY-6349 A3L01_02245 b8b90575c3b90e5c16e37480beb21acd 393 Pfam PF01494 FAD binding domain 3 319 2.7E-15 T 23-10-2018 IPR002938 FAD-binding domain GO:0071949 A3L01_02245 b8b90575c3b90e5c16e37480beb21acd 393 SUPERFAMILY SSF51905 1 328 4.42E-39 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_02245 b8b90575c3b90e5c16e37480beb21acd 393 Gene3D G3DSA:3.30.9.10 69 356 1.9E-107 T 23-10-2018 A3L01_02245 b8b90575c3b90e5c16e37480beb21acd 393 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 3 301 4.9E-76 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 A3L01_02245 b8b90575c3b90e5c16e37480beb21acd 393 Gene3D G3DSA:3.50.50.60 3 338 1.9E-107 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_02245 b8b90575c3b90e5c16e37480beb21acd 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 2.5E-10 T 23-10-2018 A3L01_02245 b8b90575c3b90e5c16e37480beb21acd 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 2.5E-10 T 23-10-2018 A3L01_02245 b8b90575c3b90e5c16e37480beb21acd 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 266 281 2.5E-10 T 23-10-2018 A3L01_06925 8de28a9158a40af2fd253abce73f55b3 392 Gene3D G3DSA:3.90.1150.10 34 384 5.8E-133 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L01_06925 8de28a9158a40af2fd253abce73f55b3 392 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A3L01_06925 8de28a9158a40af2fd253abce73f55b3 392 Pfam PF00155 Aminotransferase class I and II 34 381 4.6E-76 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L01_06925 8de28a9158a40af2fd253abce73f55b3 392 Gene3D G3DSA:3.40.640.10 65 284 5.8E-133 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L01_06925 8de28a9158a40af2fd253abce73f55b3 392 SUPERFAMILY SSF53383 10 391 2.42E-121 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L01_04455 b2172ab2953019436c9a7fea4f25d254 290 Gene3D G3DSA:3.90.1570.30 6 140 1.7E-5 T 23-10-2018 A3L01_04455 b2172ab2953019436c9a7fea4f25d254 290 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 25 119 4.8E-10 T 23-10-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain A3L01_01395 9ca15e479eac427e7fa8ce8792dda74c 146 Pfam PF12837 4Fe-4S binding domain 9 23 1.9E-5 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_01395 9ca15e479eac427e7fa8ce8792dda74c 146 Pfam PF13247 4Fe-4S dicluster domain 42 119 6.8E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_01395 9ca15e479eac427e7fa8ce8792dda74c 146 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_01395 9ca15e479eac427e7fa8ce8792dda74c 146 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 12 23 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_01395 9ca15e479eac427e7fa8ce8792dda74c 146 Gene3D G3DSA:3.30.70.20 49 100 1.8E-13 T 23-10-2018 A3L01_01395 9ca15e479eac427e7fa8ce8792dda74c 146 SUPERFAMILY SSF54862 6 125 1.74E-31 T 23-10-2018 A3L01_01395 9ca15e479eac427e7fa8ce8792dda74c 146 Gene3D G3DSA:3.30.70.20 3 40 2.1E-5 T 23-10-2018 A3L01_03475 1bf44ef93bc305880a1086389dc0da85 264 Pfam PF01022 Bacterial regulatory protein, arsR family 14 57 3.2E-8 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_03475 1bf44ef93bc305880a1086389dc0da85 264 SMART SM00418 5 80 0.0082 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_03475 1bf44ef93bc305880a1086389dc0da85 264 Pfam PF08350 Domain of unknown function (DUF1724) 202 261 2.0E-20 T 23-10-2018 IPR013561 Domain of unknown function DUF1724 A3L01_03475 1bf44ef93bc305880a1086389dc0da85 264 Gene3D G3DSA:1.10.10.10 1 75 5.2E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_03475 1bf44ef93bc305880a1086389dc0da85 264 PIRSF PIRSF006692 1 264 1.1E-68 T 23-10-2018 IPR016490 Transcriptional regulator, HTH, AF0396-type A3L01_03475 1bf44ef93bc305880a1086389dc0da85 264 SUPERFAMILY SSF46785 13 115 3.51E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_02840 d97dc318b7f8d0d3cf01ed27dd6d71eb 136 SUPERFAMILY SSF50249 71 133 1.46E-13 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_02840 d97dc318b7f8d0d3cf01ed27dd6d71eb 136 SMART SM01376 70 134 1.0E-14 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 A3L01_02840 d97dc318b7f8d0d3cf01ed27dd6d71eb 136 Pfam PF01287 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 70 134 3.4E-10 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 A3L01_02840 d97dc318b7f8d0d3cf01ed27dd6d71eb 136 TIGRFAM TIGR00037 eIF_5A: translation elongation factor IF5A 4 134 1.3E-47 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 A3L01_02840 d97dc318b7f8d0d3cf01ed27dd6d71eb 136 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 9 40 2.2E-4 T 23-10-2018 IPR013185 Translation elongation factor, KOW-like A3L01_02840 d97dc318b7f8d0d3cf01ed27dd6d71eb 136 Gene3D G3DSA:2.40.50.140 71 135 1.1E-28 T 23-10-2018 A3L01_02840 d97dc318b7f8d0d3cf01ed27dd6d71eb 136 PIRSF PIRSF003025 1 136 2.5E-44 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 A3L01_02840 d97dc318b7f8d0d3cf01ed27dd6d71eb 136 Hamap MF_00085 Translation initiation factor 5A [eif5a]. 3 133 34.514 T 23-10-2018 IPR022847 Translation elongation factor IF5A, archaeal A3L01_02840 d97dc318b7f8d0d3cf01ed27dd6d71eb 136 SUPERFAMILY SSF50104 5 78 2.16E-20 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L01_02840 d97dc318b7f8d0d3cf01ed27dd6d71eb 136 ProSitePatterns PS00302 Eukaryotic initiation factor 5A hypusine signature. 35 42 - T 23-10-2018 IPR019769 Translation elongation factor, IF5A, hypusine site GO:0003723|GO:0003746|GO:0043022|GO:0045901|GO:0045905 A3L01_02840 d97dc318b7f8d0d3cf01ed27dd6d71eb 136 Gene3D G3DSA:2.30.30.30 1 70 5.5E-28 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L01_07930 c22b31e816ba817bf1dfae20f17f4530 151 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 1 149 34.548 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 A3L01_07930 c22b31e816ba817bf1dfae20f17f4530 151 Gene3D G3DSA:3.30.70.140 1 97 1.1E-37 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily A3L01_07930 c22b31e816ba817bf1dfae20f17f4530 151 Gene3D G3DSA:2.30.30.20 98 151 7.7E-23 T 23-10-2018 A3L01_07930 c22b31e816ba817bf1dfae20f17f4530 151 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 4 96 1.5E-33 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal A3L01_07930 c22b31e816ba817bf1dfae20f17f4530 151 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 6 97 1.0E-35 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal A3L01_07930 c22b31e816ba817bf1dfae20f17f4530 151 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 2 148 8.8E-62 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 A3L01_07930 c22b31e816ba817bf1dfae20f17f4530 151 SUPERFAMILY SSF57825 100 148 5.76E-16 T 23-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily A3L01_07930 c22b31e816ba817bf1dfae20f17f4530 151 SUPERFAMILY SSF54893 3 98 1.44E-33 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily A3L01_07930 c22b31e816ba817bf1dfae20f17f4530 151 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 100 147 4.2E-19 T 23-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal A3L01_04305 b2a4af9861a1efa38de49e6db67800b5 290 Gene3D G3DSA:3.30.2010.10 61 150 2.7E-31 T 23-10-2018 A3L01_04305 b2a4af9861a1efa38de49e6db67800b5 290 Hamap MF_00188 Protease HtpX [htpX]. 6 280 30.018 T 23-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 A3L01_04305 b2a4af9861a1efa38de49e6db67800b5 290 Pfam PF01435 Peptidase family M48 67 280 5.5E-36 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A3L01_02880 2414d2b1654b0bc3dddade20fb1ef736 315 Gene3D G3DSA:3.40.50.1370 138 297 2.0E-138 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L01_02880 2414d2b1654b0bc3dddade20fb1ef736 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L01_02880 2414d2b1654b0bc3dddade20fb1ef736 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L01_02880 2414d2b1654b0bc3dddade20fb1ef736 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 227 237 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L01_02880 2414d2b1654b0bc3dddade20fb1ef736 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L01_02880 2414d2b1654b0bc3dddade20fb1ef736 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 289 300 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L01_02880 2414d2b1654b0bc3dddade20fb1ef736 315 Gene3D G3DSA:3.40.50.1370 10 307 2.0E-138 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L01_02880 2414d2b1654b0bc3dddade20fb1ef736 315 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 1.4E-50 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A3L01_02880 2414d2b1654b0bc3dddade20fb1ef736 315 SUPERFAMILY SSF53671 4 313 3.8E-116 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L01_02880 2414d2b1654b0bc3dddade20fb1ef736 315 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 310 9.2E-146 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L01_02880 2414d2b1654b0bc3dddade20fb1ef736 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 275 298 2.2E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L01_02880 2414d2b1654b0bc3dddade20fb1ef736 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 2.2E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L01_02880 2414d2b1654b0bc3dddade20fb1ef736 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 2.2E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L01_02880 2414d2b1654b0bc3dddade20fb1ef736 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 263 272 2.2E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L01_02880 2414d2b1654b0bc3dddade20fb1ef736 315 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L01_02880 2414d2b1654b0bc3dddade20fb1ef736 315 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 311 85.305 T 23-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 A3L01_02880 2414d2b1654b0bc3dddade20fb1ef736 315 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 308 9.5E-66 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A3L01_10010 6ec9daba4e63b86cf05ca485ecdacf3e 396 SUPERFAMILY SSF53335 78 389 2.16E-67 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_10010 6ec9daba4e63b86cf05ca485ecdacf3e 396 Gene3D G3DSA:3.30.750.80 72 178 5.6E-37 T 23-10-2018 A3L01_10010 6ec9daba4e63b86cf05ca485ecdacf3e 396 SUPERFAMILY SSF88697 1 69 1.59E-17 T 23-10-2018 IPR015947 PUA-like superfamily A3L01_10010 6ec9daba4e63b86cf05ca485ecdacf3e 396 Pfam PF01472 PUA domain 3 75 1.2E-14 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L01_10010 6ec9daba4e63b86cf05ca485ecdacf3e 396 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 170 333 9.2E-20 T 23-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 A3L01_10010 6ec9daba4e63b86cf05ca485ecdacf3e 396 Gene3D G3DSA:2.30.130.10 1 70 4.8E-21 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L01_10010 6ec9daba4e63b86cf05ca485ecdacf3e 396 SMART SM00359 2 87 1.2E-23 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L01_10010 6ec9daba4e63b86cf05ca485ecdacf3e 396 Gene3D G3DSA:3.40.50.150 179 396 7.6E-71 T 23-10-2018 A3L01_01375 e5cad605a00b982885c426690a580019 334 SUPERFAMILY SSF55060 183 329 1.36E-35 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A3L01_01375 e5cad605a00b982885c426690a580019 334 Pfam PF08544 GHMP kinases C terminal 245 310 1.0E-12 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain A3L01_01375 e5cad605a00b982885c426690a580019 334 Gene3D G3DSA:3.30.230.10 1 182 1.4E-50 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L01_01375 e5cad605a00b982885c426690a580019 334 Pfam PF00288 GHMP kinases N terminal domain 103 169 5.4E-16 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A3L01_01375 e5cad605a00b982885c426690a580019 334 SUPERFAMILY SSF54211 3 180 8.35E-46 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L01_01375 e5cad605a00b982885c426690a580019 334 Gene3D G3DSA:3.30.70.890 187 319 3.6E-40 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A3L01_01375 e5cad605a00b982885c426690a580019 334 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 7 298 4.8E-84 T 23-10-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A3L01_01375 e5cad605a00b982885c426690a580019 334 Hamap MF_00217 Mevalonate kinase [mvk]. 3 327 58.728 T 23-10-2018 IPR022937 Mevalonate kinase, archaeal GO:0004496 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922 A3L01_01375 e5cad605a00b982885c426690a580019 334 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 109 120 - T 23-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 A3L01_01375 e5cad605a00b982885c426690a580019 334 PRINTS PR00959 Mevalonate kinase family signature 150 169 6.0E-29 T 23-10-2018 A3L01_01375 e5cad605a00b982885c426690a580019 334 PRINTS PR00959 Mevalonate kinase family signature 107 129 6.0E-29 T 23-10-2018 A3L01_01375 e5cad605a00b982885c426690a580019 334 PRINTS PR00959 Mevalonate kinase family signature 7 31 6.0E-29 T 23-10-2018 A3L01_01375 e5cad605a00b982885c426690a580019 334 PRINTS PR00959 Mevalonate kinase family signature 283 300 6.0E-29 T 23-10-2018 A3L01_07820 4ce8811789b118b5b8001cb0eb2e41d4 171 SUPERFAMILY SSF53032 79 169 1.57E-28 T 23-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A3L01_07820 4ce8811789b118b5b8001cb0eb2e41d4 171 TIGRFAM TIGR00324 endA: tRNA-intron lyase 8 169 6.0E-38 T 23-10-2018 IPR006676 tRNA-splicing endonuclease GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A3L01_07820 4ce8811789b118b5b8001cb0eb2e41d4 171 SUPERFAMILY SSF55267 6 77 3.73E-19 T 23-10-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 A3L01_07820 4ce8811789b118b5b8001cb0eb2e41d4 171 Pfam PF02778 tRNA intron endonuclease, N-terminal domain 8 69 2.6E-20 T 23-10-2018 IPR006678 tRNA intron endonuclease, N-terminal GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A3L01_07820 4ce8811789b118b5b8001cb0eb2e41d4 171 Gene3D G3DSA:3.40.1170.20 8 72 1.6E-17 T 23-10-2018 A3L01_07820 4ce8811789b118b5b8001cb0eb2e41d4 171 PIRSF PIRSF005285 8 171 9.7E-64 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 A3L01_07820 4ce8811789b118b5b8001cb0eb2e41d4 171 Gene3D G3DSA:3.40.1350.10 79 171 2.0E-31 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A3L01_07820 4ce8811789b118b5b8001cb0eb2e41d4 171 Hamap MF_01833 tRNA-splicing endonuclease [endA]. 5 171 33.069 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 A3L01_07820 4ce8811789b118b5b8001cb0eb2e41d4 171 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 80 163 1.3E-29 T 23-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A3L01_01675 9cf5b432e2da4fcaa5c5a98bf70adbf2 772 Pfam PF00708 Acylphosphatase 4 87 2.6E-24 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L01_01675 9cf5b432e2da4fcaa5c5a98bf70adbf2 772 SUPERFAMILY SSF55821 175 390 5.49E-45 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A3L01_01675 9cf5b432e2da4fcaa5c5a98bf70adbf2 772 SUPERFAMILY SSF54975 1 88 5.23E-26 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L01_01675 9cf5b432e2da4fcaa5c5a98bf70adbf2 772 Pfam PF07503 HypF finger 158 191 4.2E-15 T 23-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 A3L01_01675 9cf5b432e2da4fcaa5c5a98bf70adbf2 772 Pfam PF07503 HypF finger 108 141 1.5E-16 T 23-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 A3L01_01675 9cf5b432e2da4fcaa5c5a98bf70adbf2 772 SUPERFAMILY SSF53067 403 737 1.36E-6 T 23-10-2018 A3L01_01675 9cf5b432e2da4fcaa5c5a98bf70adbf2 772 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 7 755 1.1E-263 T 23-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 A3L01_01675 9cf5b432e2da4fcaa5c5a98bf70adbf2 772 Gene3D G3DSA:3.30.110.120 252 371 7.8E-145 T 23-10-2018 A3L01_01675 9cf5b432e2da4fcaa5c5a98bf70adbf2 772 Pfam PF01300 Telomere recombination 208 383 8.4E-46 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 A3L01_01675 9cf5b432e2da4fcaa5c5a98bf70adbf2 772 Gene3D G3DSA:3.30.420.350 486 743 8.7E-103 T 23-10-2018 A3L01_01675 9cf5b432e2da4fcaa5c5a98bf70adbf2 772 PIRSF PIRSF006256 1 764 6.5E-283 T 23-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 A3L01_01675 9cf5b432e2da4fcaa5c5a98bf70adbf2 772 Gene3D G3DSA:3.90.870.50 6 362 7.8E-145 T 23-10-2018 A3L01_01675 9cf5b432e2da4fcaa5c5a98bf70adbf2 772 Gene3D G3DSA:3.30.420.360 383 755 8.7E-103 T 23-10-2018 A3L01_09165 f357dc5773a154440f15bd040720e25b 185 Pfam PF01022 Bacterial regulatory protein, arsR family 18 63 9.4E-14 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_09165 f357dc5773a154440f15bd040720e25b 185 Gene3D G3DSA:1.10.10.10 1 85 5.9E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_09165 f357dc5773a154440f15bd040720e25b 185 SMART SM00418 11 96 1.3E-12 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_09165 f357dc5773a154440f15bd040720e25b 185 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 2.2E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_09165 f357dc5773a154440f15bd040720e25b 185 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 2.2E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_09165 f357dc5773a154440f15bd040720e25b 185 SUPERFAMILY SSF46785 4 128 1.95E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_07880 b1be77b09bc0423768776f6062c9b00f 262 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 8 253 3.2E-16 T 23-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 A3L01_07880 b1be77b09bc0423768776f6062c9b00f 262 SUPERFAMILY SSF53213 6 259 3.66E-25 T 23-10-2018 A3L01_07880 b1be77b09bc0423768776f6062c9b00f 262 Gene3D G3DSA:3.40.830.10 1 262 5.7E-72 T 23-10-2018 A3L01_10230 c37a47f8f141eb9071b996fcd2427d9e 376 Gene3D G3DSA:3.40.50.2000 14 354 2.5E-76 T 23-10-2018 A3L01_10230 c37a47f8f141eb9071b996fcd2427d9e 376 Gene3D G3DSA:3.40.50.2000 170 345 2.5E-76 T 23-10-2018 A3L01_10230 c37a47f8f141eb9071b996fcd2427d9e 376 Pfam PF13439 Glycosyltransferase Family 4 14 173 3.8E-16 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L01_10230 c37a47f8f141eb9071b996fcd2427d9e 376 SUPERFAMILY SSF53756 4 361 5.83E-85 T 23-10-2018 A3L01_10230 c37a47f8f141eb9071b996fcd2427d9e 376 Pfam PF00534 Glycosyl transferases group 1 186 340 8.7E-47 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L01_04130 2771c693c32090a0cf27acb82207472c 331 Pfam PF02475 Met-10+ like-protein 82 277 2.5E-70 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A3L01_04130 2771c693c32090a0cf27acb82207472c 331 Gene3D G3DSA:3.30.300.110 57 142 1.6E-28 T 23-10-2018 A3L01_04130 2771c693c32090a0cf27acb82207472c 331 SUPERFAMILY SSF53335 72 329 3.41E-71 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_04130 2771c693c32090a0cf27acb82207472c 331 Gene3D G3DSA:3.40.50.150 143 331 2.6E-56 T 23-10-2018 A3L01_04130 2771c693c32090a0cf27acb82207472c 331 Gene3D G3DSA:3.30.70.2580 1 56 5.6E-7 T 23-10-2018 A3L01_02400 8ddec63441268d680d52ae46d35360e0 170 SUPERFAMILY SSF54814 44 96 3.34E-8 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L01_02400 8ddec63441268d680d52ae46d35360e0 170 Pfam PF13184 NusA-like KH domain 57 124 2.4E-11 T 23-10-2018 IPR025249 KH domain, NusA-like GO:0003723 A3L01_02400 8ddec63441268d680d52ae46d35360e0 170 SMART SM00322 57 119 9.7E-5 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L01_02400 8ddec63441268d680d52ae46d35360e0 170 Gene3D G3DSA:3.30.300.20 48 97 5.7E-10 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L01_08580 ee70bb962eba3f3a31bcc60af789cfe5 285 Gene3D G3DSA:3.40.50.150 97 274 2.1E-26 T 23-10-2018 A3L01_08580 ee70bb962eba3f3a31bcc60af789cfe5 285 Pfam PF13649 Methyltransferase domain 129 230 3.3E-10 T 23-10-2018 A3L01_08580 ee70bb962eba3f3a31bcc60af789cfe5 285 SUPERFAMILY SSF53335 68 262 6.49E-37 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_07920 b97164798f4f7cbc21248db3a94f4b4a 296 Gene3D G3DSA:1.10.10.60 15 51 1.3E-6 T 23-10-2018 A3L01_07920 b97164798f4f7cbc21248db3a94f4b4a 296 SMART SM00530 19 74 4.5E-4 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L01_07920 b97164798f4f7cbc21248db3a94f4b4a 296 SUPERFAMILY SSF53639 126 293 1.65E-45 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L01_07920 b97164798f4f7cbc21248db3a94f4b4a 296 Pfam PF10120 Thiamine-phosphate synthase 133 290 2.6E-46 T 23-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L01_07920 b97164798f4f7cbc21248db3a94f4b4a 296 SUPERFAMILY SSF47413 14 64 2.74E-8 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L01_07920 b97164798f4f7cbc21248db3a94f4b4a 296 Pfam PF01381 Helix-turn-helix 23 66 8.5E-7 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L01_07920 b97164798f4f7cbc21248db3a94f4b4a 296 Gene3D G3DSA:3.40.225.10 124 296 2.3E-43 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L01_04725 7f9f6970a54c4c16017a14dbe425d69a 478 ProSitePatterns PS00110 Pyruvate kinase active site signature. 216 228 - T 23-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L01_04725 7f9f6970a54c4c16017a14dbe425d69a 478 Gene3D G3DSA:3.40.1380.20 337 474 3.9E-167 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L01_04725 7f9f6970a54c4c16017a14dbe425d69a 478 SUPERFAMILY SSF52935 324 478 2.35E-32 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L01_04725 7f9f6970a54c4c16017a14dbe425d69a 478 SUPERFAMILY SSF51621 4 340 2.06E-94 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A3L01_04725 7f9f6970a54c4c16017a14dbe425d69a 478 Gene3D G3DSA:2.40.33.10 74 170 3.9E-167 T 23-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L01_04725 7f9f6970a54c4c16017a14dbe425d69a 478 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 478 3.4E-169 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L01_04725 7f9f6970a54c4c16017a14dbe425d69a 478 Gene3D G3DSA:3.20.20.60 7 336 3.9E-167 T 23-10-2018 A3L01_04725 7f9f6970a54c4c16017a14dbe425d69a 478 SUPERFAMILY SSF50800 75 166 1.24E-23 T 23-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily A3L01_04725 7f9f6970a54c4c16017a14dbe425d69a 478 PRINTS PR01050 Pyruvate kinase family signature 63 79 1.1E-64 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L01_04725 7f9f6970a54c4c16017a14dbe425d69a 478 PRINTS PR01050 Pyruvate kinase family signature 218 244 1.1E-64 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L01_04725 7f9f6970a54c4c16017a14dbe425d69a 478 PRINTS PR01050 Pyruvate kinase family signature 295 313 1.1E-64 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L01_04725 7f9f6970a54c4c16017a14dbe425d69a 478 PRINTS PR01050 Pyruvate kinase family signature 188 202 1.1E-64 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L01_04725 7f9f6970a54c4c16017a14dbe425d69a 478 PRINTS PR01050 Pyruvate kinase family signature 245 269 1.1E-64 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L01_04725 7f9f6970a54c4c16017a14dbe425d69a 478 PRINTS PR01050 Pyruvate kinase family signature 270 294 1.1E-64 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L01_04725 7f9f6970a54c4c16017a14dbe425d69a 478 PRINTS PR01050 Pyruvate kinase family signature 314 330 1.1E-64 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L01_04725 7f9f6970a54c4c16017a14dbe425d69a 478 Pfam PF00224 Pyruvate kinase, barrel domain 6 338 1.1E-118 T 23-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L01_04725 7f9f6970a54c4c16017a14dbe425d69a 478 Pfam PF02887 Pyruvate kinase, alpha/beta domain 368 475 1.3E-23 T 23-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L01_01150 cd4bf307731a0d585c09e9e3cc8ecf48 481 Pfam PF00344 SecY translocase 72 460 4.4E-71 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L01_01150 cd4bf307731a0d585c09e9e3cc8ecf48 481 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 27 469 1.3E-92 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L01_01150 cd4bf307731a0d585c09e9e3cc8ecf48 481 SUPERFAMILY SSF103491 9 467 3.4E-109 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L01_01150 cd4bf307731a0d585c09e9e3cc8ecf48 481 PIRSF PIRSF004557 5 481 8.9E-103 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L01_01150 cd4bf307731a0d585c09e9e3cc8ecf48 481 Gene3D G3DSA:1.10.3370.10 26 481 2.6E-178 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L01_01150 cd4bf307731a0d585c09e9e3cc8ecf48 481 ProSitePatterns PS00756 Protein secY signature 2. 178 195 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L01_01150 cd4bf307731a0d585c09e9e3cc8ecf48 481 ProSitePatterns PS00755 Protein secY signature 1. 72 91 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L01_01150 cd4bf307731a0d585c09e9e3cc8ecf48 481 Pfam PF10559 Plug domain of Sec61p 38 71 2.8E-11 T 23-10-2018 IPR019561 Translocon Sec61/SecY, plug domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L01_01150 cd4bf307731a0d585c09e9e3cc8ecf48 481 Hamap MF_01465 Protein translocase subunit SecY [secY]. 17 476 20.257 T 23-10-2018 IPR026593 Protein translocase subunit SecY A3L01_01150 cd4bf307731a0d585c09e9e3cc8ecf48 481 PRINTS PR00303 Preprotein translocase SecY subunit signature 30 48 1.9E-8 T 23-10-2018 A3L01_01150 cd4bf307731a0d585c09e9e3cc8ecf48 481 PRINTS PR00303 Preprotein translocase SecY subunit signature 159 184 1.9E-8 T 23-10-2018 A3L01_01150 cd4bf307731a0d585c09e9e3cc8ecf48 481 PRINTS PR00303 Preprotein translocase SecY subunit signature 445 463 1.9E-8 T 23-10-2018 A3L01_01150 cd4bf307731a0d585c09e9e3cc8ecf48 481 PRINTS PR00303 Preprotein translocase SecY subunit signature 185 208 1.9E-8 T 23-10-2018 A3L01_02920 64f05e1d561595e7ac7f353dc7b85c8c 277 Pfam PF09968 Uncharacterized protein domain (DUF2202) 61 221 3.0E-69 T 23-10-2018 IPR019243 Domain of unknown function DUF2202 A3L01_02920 64f05e1d561595e7ac7f353dc7b85c8c 277 SUPERFAMILY SSF47240 61 201 3.75E-13 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L01_02920 64f05e1d561595e7ac7f353dc7b85c8c 277 Gene3D G3DSA:1.20.1260.10 56 228 4.9E-73 T 23-10-2018 IPR012347 Ferritin-like A3L01_04525 003770d802da45b6e01afb834f80274c 361 Pfam PF10130 PIN domain 65 197 6.5E-11 T 23-10-2018 IPR002716 PIN domain A3L01_04375 1d0fb5350b97ae549f74596e26348879 285 SUPERFAMILY SSF51621 4 262 1.92E-102 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A3L01_04375 1d0fb5350b97ae549f74596e26348879 285 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 11 262 1.8E-90 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A3L01_04375 1d0fb5350b97ae549f74596e26348879 285 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 262 41.248 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A3L01_04375 1d0fb5350b97ae549f74596e26348879 285 Gene3D G3DSA:3.20.20.60 2 272 2.8E-109 T 23-10-2018 A3L01_04375 1d0fb5350b97ae549f74596e26348879 285 PIRSF PIRSF000388 1 265 2.5E-103 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A3L01_04375 1d0fb5350b97ae549f74596e26348879 285 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 257 1.0E-106 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A3L01_09980 4c3797ff84a4c76e4fca2b9e4eeee98b 346 TIGRFAM TIGR00335 primase_sml: putative DNA primase, eukaryotic-type, small subunit 12 329 2.6E-58 T 23-10-2018 IPR014052 DNA primase, small subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 A3L01_09980 4c3797ff84a4c76e4fca2b9e4eeee98b 346 SUPERFAMILY SSF56747 6 341 2.4E-92 T 23-10-2018 A3L01_09980 4c3797ff84a4c76e4fca2b9e4eeee98b 346 Hamap MF_00700 DNA primase small subunit PriS [priS]. 11 343 23.355 T 23-10-2018 IPR023639 DNA primase small subunit PriS GO:0003896 A3L01_09980 4c3797ff84a4c76e4fca2b9e4eeee98b 346 Pfam PF01896 DNA primase small subunit 96 303 4.6E-13 T 23-10-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 A3L01_09980 4c3797ff84a4c76e4fca2b9e4eeee98b 346 Gene3D G3DSA:3.90.920.10 9 326 3.4E-120 T 23-10-2018 A3L01_09980 4c3797ff84a4c76e4fca2b9e4eeee98b 346 Gene3D G3DSA:1.10.8.160 176 277 3.4E-120 T 23-10-2018 A3L01_02870 028b280a0c2ce17897aed7bcb966d4b1 309 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 14 102 1.0E-19 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L01_02870 028b280a0c2ce17897aed7bcb966d4b1 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 233 249 6.6E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_02870 028b280a0c2ce17897aed7bcb966d4b1 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 183 195 6.6E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_02870 028b280a0c2ce17897aed7bcb966d4b1 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 117 127 6.6E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_02870 028b280a0c2ce17897aed7bcb966d4b1 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 291 308 6.6E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_02870 028b280a0c2ce17897aed7bcb966d4b1 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 88 102 6.6E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_02870 028b280a0c2ce17897aed7bcb966d4b1 309 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 182 193 - T 23-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 A3L01_02870 028b280a0c2ce17897aed7bcb966d4b1 309 Pfam PF01189 16S rRNA methyltransferase RsmB/F 106 307 1.6E-58 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L01_02870 028b280a0c2ce17897aed7bcb966d4b1 309 Gene3D G3DSA:3.40.50.150 103 309 2.3E-69 T 23-10-2018 A3L01_02870 028b280a0c2ce17897aed7bcb966d4b1 309 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 42 308 2.7E-90 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L01_02870 028b280a0c2ce17897aed7bcb966d4b1 309 SUPERFAMILY SSF53335 7 308 7.5E-77 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_02870 028b280a0c2ce17897aed7bcb966d4b1 309 Gene3D G3DSA:3.30.70.3130 1 101 1.6E-35 T 23-10-2018 A3L01_01650 c2fc1acf878441221345faa198fab4b0 376 Pfam PF01513 ATP-NAD kinase 2 374 8.0E-45 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A3L01_01650 c2fc1acf878441221345faa198fab4b0 376 PIRSF PIRSF016907 1 376 2.1E-139 T 23-10-2018 IPR011386 Putative ATP-NAD kinase A3L01_01650 c2fc1acf878441221345faa198fab4b0 376 SUPERFAMILY SSF111331 98 149 3.92E-6 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A3L01_02710 8f30304b9a09b789a415adda3e880873 439 Gene3D G3DSA:2.30.30.520 2 78 1.7E-20 T 23-10-2018 IPR037222 GatD, N-terminal A3L01_02710 8f30304b9a09b789a415adda3e880873 439 SUPERFAMILY SSF53774 87 436 2.09E-120 T 23-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 A3L01_02710 8f30304b9a09b789a415adda3e880873 439 PIRSF PIRSF500175 13 437 6.4E-189 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 A3L01_02710 8f30304b9a09b789a415adda3e880873 439 PRINTS PR00139 Asparaginase/glutaminase family signature 354 372 3.0E-19 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L01_02710 8f30304b9a09b789a415adda3e880873 439 PRINTS PR00139 Asparaginase/glutaminase family signature 95 106 3.0E-19 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L01_02710 8f30304b9a09b789a415adda3e880873 439 PRINTS PR00139 Asparaginase/glutaminase family signature 171 189 3.0E-19 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L01_02710 8f30304b9a09b789a415adda3e880873 439 TIGRFAM TIGR02153 gatD_arch: glutamyl-tRNA(Gln) amidotransferase, subunit D 31 433 1.1E-194 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 A3L01_02710 8f30304b9a09b789a415adda3e880873 439 Pfam PF00710 Asparaginase, N-terminal 95 287 6.6E-63 T 23-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A3L01_02710 8f30304b9a09b789a415adda3e880873 439 Gene3D G3DSA:3.40.50.40 302 439 8.7E-57 T 23-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 A3L01_02710 8f30304b9a09b789a415adda3e880873 439 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 97 105 - T 23-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 A3L01_02710 8f30304b9a09b789a415adda3e880873 439 SUPERFAMILY SSF141300 4 75 3.66E-18 T 23-10-2018 IPR037222 GatD, N-terminal A3L01_02710 8f30304b9a09b789a415adda3e880873 439 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 172 182 - T 23-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 A3L01_02710 8f30304b9a09b789a415adda3e880873 439 PIRSF PIRSF001220 90 428 5.7E-112 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L01_02710 8f30304b9a09b789a415adda3e880873 439 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 92 429 1.9E-147 T 23-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 A3L01_02710 8f30304b9a09b789a415adda3e880873 439 SMART SM00870 94 417 2.6E-155 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L01_02710 8f30304b9a09b789a415adda3e880873 439 Hamap MF_00586 Glutamyl-tRNA(Gln) amidotransferase subunit D [gatD]. 19 433 48.922 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 A3L01_02710 8f30304b9a09b789a415adda3e880873 439 Gene3D G3DSA:3.40.50.1170 81 301 5.8E-87 T 23-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 A3L01_00700 076a91ec7de373fa69790dabe7e1cbba 394 SUPERFAMILY SSF103473 12 392 7.85E-59 T 23-10-2018 IPR036259 MFS transporter superfamily A3L01_00700 076a91ec7de373fa69790dabe7e1cbba 394 Gene3D G3DSA:1.20.1250.20 209 394 1.5E-21 T 23-10-2018 A3L01_00700 076a91ec7de373fa69790dabe7e1cbba 394 Pfam PF07690 Major Facilitator Superfamily 19 260 2.5E-25 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L01_00700 076a91ec7de373fa69790dabe7e1cbba 394 Gene3D G3DSA:1.20.1250.20 12 203 4.4E-26 T 23-10-2018 A3L01_01030 994b4bd64ebeab61f168e549f2780628 347 Gene3D G3DSA:3.30.1430.10 77 188 3.7E-122 T 23-10-2018 A3L01_01030 994b4bd64ebeab61f168e549f2780628 347 Pfam PF00297 Ribosomal protein L3 3 347 1.7E-90 T 23-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01030 994b4bd64ebeab61f168e549f2780628 347 TIGRFAM TIGR03626 L3_arch: ribosomal protein uL3 5 346 3.7E-136 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01030 994b4bd64ebeab61f168e549f2780628 347 Gene3D G3DSA:4.10.960.10 6 257 3.7E-122 T 23-10-2018 A3L01_01030 994b4bd64ebeab61f168e549f2780628 347 SUPERFAMILY SSF50447 3 347 1.24E-95 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L01_01030 994b4bd64ebeab61f168e549f2780628 347 Gene3D G3DSA:2.40.30.10 39 327 3.7E-122 T 23-10-2018 A3L01_01030 994b4bd64ebeab61f168e549f2780628 347 Hamap MF_01325_A 50S ribosomal protein L3 [rplC]. 1 347 49.888 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01030 994b4bd64ebeab61f168e549f2780628 347 ProSitePatterns PS00474 Ribosomal protein L3 signature. 193 216 - T 23-10-2018 IPR019926 Ribosomal protein L3, conserved site A3L01_03790 8a33f7b10ae2b23e4296fafd60187cf6 580 TIGRFAM TIGR00432 arcsn_tRNA_tgt: tRNA-guanine(15) transglycosylase 6 387 8.7E-171 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L01_03790 8a33f7b10ae2b23e4296fafd60187cf6 580 SMART SM00359 505 579 2.1E-18 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L01_03790 8a33f7b10ae2b23e4296fafd60187cf6 580 Gene3D G3DSA:3.90.1020.10 357 426 4.6E-27 T 23-10-2018 IPR038370 TGT, C1 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L01_03790 8a33f7b10ae2b23e4296fafd60187cf6 580 SUPERFAMILY SSF51713 4 354 1.1E-115 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L01_03790 8a33f7b10ae2b23e4296fafd60187cf6 580 Gene3D G3DSA:3.10.450.90 427 501 5.3E-27 T 23-10-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L01_03790 8a33f7b10ae2b23e4296fafd60187cf6 580 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 486 575 1.2E-9 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L01_03790 8a33f7b10ae2b23e4296fafd60187cf6 580 SUPERFAMILY SSF88802 357 502 6.34E-41 T 23-10-2018 A3L01_03790 8a33f7b10ae2b23e4296fafd60187cf6 580 Gene3D G3DSA:2.30.130.10 502 579 3.8E-32 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L01_03790 8a33f7b10ae2b23e4296fafd60187cf6 580 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 436 503 7.1E-22 T 23-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L01_03790 8a33f7b10ae2b23e4296fafd60187cf6 580 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 338 1.9E-89 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L01_03790 8a33f7b10ae2b23e4296fafd60187cf6 580 Pfam PF14809 C1 domain of tRNA-guanine transglycosylase dimerisation 357 426 1.0E-39 T 23-10-2018 IPR032729 tRNA-guanine(15) transglycosylase, C1 domain MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L01_03790 8a33f7b10ae2b23e4296fafd60187cf6 580 Pfam PF01702 Queuine tRNA-ribosyltransferase 109 330 6.5E-42 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L01_03790 8a33f7b10ae2b23e4296fafd60187cf6 580 Gene3D G3DSA:3.20.20.105 1 356 6.2E-124 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L01_03790 8a33f7b10ae2b23e4296fafd60187cf6 580 SUPERFAMILY SSF88697 504 578 9.39E-20 T 23-10-2018 IPR015947 PUA-like superfamily A3L01_03790 8a33f7b10ae2b23e4296fafd60187cf6 580 Pfam PF01472 PUA domain 506 577 4.8E-14 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L01_03790 8a33f7b10ae2b23e4296fafd60187cf6 580 Hamap MF_01634 tRNA-guanine(15) transglycosylase [tgtA]. 6 531 48.641 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L01_05625 fd0f5b15e08247ee01280447cded99a6 153 Pfam PF09123 Domain of unknown function (DUF1931) 11 150 2.6E-46 T 23-10-2018 IPR015207 Protein of unknown function DUF1931 A3L01_05625 fd0f5b15e08247ee01280447cded99a6 153 SUPERFAMILY SSF47113 2 153 4.54E-52 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L01_05625 fd0f5b15e08247ee01280447cded99a6 153 Gene3D G3DSA:1.10.20.10 5 153 9.0E-37 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L01_06980 d66ac0a190f6dfa2f2be41e376e53219 429 Pfam PF12698 ABC-2 family transporter protein 19 404 2.0E-34 T 23-10-2018 A3L01_06980 d66ac0a190f6dfa2f2be41e376e53219 429 Gene3D G3DSA:3.40.1710.10 41 202 1.9E-31 T 23-10-2018 A3L01_07275 b860d321e7aca2694bdcfbf295759645 418 SUPERFAMILY SSF53383 16 411 9.11E-121 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L01_07275 b860d321e7aca2694bdcfbf295759645 418 Gene3D G3DSA:3.40.640.10 79 304 1.8E-162 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L01_07275 b860d321e7aca2694bdcfbf295759645 418 Pfam PF00155 Aminotransferase class I and II 58 405 5.9E-40 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L01_07275 b860d321e7aca2694bdcfbf295759645 418 Gene3D G3DSA:3.90.1150.10 34 409 1.8E-162 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L01_09395 aaedb84e17dd6cfef811a65e6e5eef04 438 SUPERFAMILY SSF48179 210 303 5.78E-32 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A3L01_09395 aaedb84e17dd6cfef811a65e6e5eef04 438 SMART SM00984 328 426 3.8E-35 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L01_09395 aaedb84e17dd6cfef811a65e6e5eef04 438 Gene3D G3DSA:3.40.50.720 209 437 1.5E-73 T 23-10-2018 A3L01_09395 aaedb84e17dd6cfef811a65e6e5eef04 438 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 19 190 7.1E-40 T 23-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L01_09395 aaedb84e17dd6cfef811a65e6e5eef04 438 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 19 422 1.2E-132 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L01_09395 aaedb84e17dd6cfef811a65e6e5eef04 438 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 328 424 1.6E-27 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L01_09395 aaedb84e17dd6cfef811a65e6e5eef04 438 PIRSF PIRSF000124 17 436 5.3E-72 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L01_09395 aaedb84e17dd6cfef811a65e6e5eef04 438 SUPERFAMILY SSF52413 317 425 5.36E-30 T 23-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 A3L01_09395 aaedb84e17dd6cfef811a65e6e5eef04 438 SUPERFAMILY SSF51735 19 204 2.27E-44 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_09395 aaedb84e17dd6cfef811a65e6e5eef04 438 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 210 301 3.4E-30 T 23-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L01_09395 aaedb84e17dd6cfef811a65e6e5eef04 438 PIRSF PIRSF500136 7 438 5.5E-162 T 23-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A3L01_09395 aaedb84e17dd6cfef811a65e6e5eef04 438 Gene3D G3DSA:3.40.50.720 3 207 1.1E-62 T 23-10-2018 A3L01_05880 05bbdcf587a2bf24bb0a91ef1369ed7d 280 Hamap MF_02055 Tyrosine recombinase XerA [xerA]. 3 273 42.856 T 23-10-2018 IPR033686 Tyrosine recombinase XerA A3L01_05880 05bbdcf587a2bf24bb0a91ef1369ed7d 280 Gene3D G3DSA:1.10.443.10 90 280 3.8E-77 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A3L01_05880 05bbdcf587a2bf24bb0a91ef1369ed7d 280 Gene3D G3DSA:1.10.150.130 2 89 2.4E-21 T 23-10-2018 IPR010998 Integrase/recombinase, N-terminal A3L01_05880 05bbdcf587a2bf24bb0a91ef1369ed7d 280 SUPERFAMILY SSF56349 3 269 1.06E-60 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A3L01_05880 05bbdcf587a2bf24bb0a91ef1369ed7d 280 Pfam PF00589 Phage integrase family 98 261 1.4E-48 T 23-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A3L01_05880 05bbdcf587a2bf24bb0a91ef1369ed7d 280 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 7 76 4.0E-8 T 23-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A3L01_08245 206890757f062d8496f3156bbd41eff9 305 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 38 269 2.7E-20 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L01_08245 206890757f062d8496f3156bbd41eff9 305 PIRSF PIRSF005647 36 301 4.6E-63 T 23-10-2018 IPR014433 Nickel insertion ATPase/GTPase (CO dehydrogenase maturation factor), CooC type A3L01_08245 206890757f062d8496f3156bbd41eff9 305 Gene3D G3DSA:3.40.50.300 36 298 4.7E-56 T 23-10-2018 A3L01_08245 206890757f062d8496f3156bbd41eff9 305 SUPERFAMILY SSF52540 28 269 3.88E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_05365 6497a4fb9a8c71c2b706134566002911 925 Pfam PF08494 DEAD/H associated 583 750 4.7E-18 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 A3L01_05365 6497a4fb9a8c71c2b706134566002911 925 SMART SM00490 259 341 2.2E-24 T 23-10-2018 IPR001650 Helicase, C-terminal A3L01_05365 6497a4fb9a8c71c2b706134566002911 925 Gene3D G3DSA:3.40.50.300 4 202 2.6E-46 T 23-10-2018 A3L01_05365 6497a4fb9a8c71c2b706134566002911 925 PIRSF PIRSF037307 1 912 0.0 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 A3L01_05365 6497a4fb9a8c71c2b706134566002911 925 Pfam PF00270 DEAD/DEAH box helicase 18 182 8.7E-27 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L01_05365 6497a4fb9a8c71c2b706134566002911 925 SUPERFAMILY SSF52540 27 350 3.63E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_05365 6497a4fb9a8c71c2b706134566002911 925 Pfam PF00271 Helicase conserved C-terminal domain 242 336 9.4E-19 T 23-10-2018 IPR001650 Helicase, C-terminal A3L01_05365 6497a4fb9a8c71c2b706134566002911 925 Gene3D G3DSA:3.40.50.300 222 372 1.0E-29 T 23-10-2018 A3L01_05365 6497a4fb9a8c71c2b706134566002911 925 SMART SM00487 12 210 8.7E-37 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L01_07200 37c2d137f95aac9c8ba6fac10b8f568a 190 Gene3D G3DSA:3.30.310.10 16 97 6.5E-33 T 23-10-2018 IPR012295 TBP domain superfamily A3L01_07200 37c2d137f95aac9c8ba6fac10b8f568a 190 Hamap MF_00408 TATA-box-binding protein [tbp]. 5 184 37.711 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L01_07200 37c2d137f95aac9c8ba6fac10b8f568a 190 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 129 178 - T 23-10-2018 IPR030491 TATA-box binding protein, conserved site A3L01_07200 37c2d137f95aac9c8ba6fac10b8f568a 190 PRINTS PR00686 Transcription initiation factor TFIID signature 125 140 1.2E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L01_07200 37c2d137f95aac9c8ba6fac10b8f568a 190 PRINTS PR00686 Transcription initiation factor TFIID signature 11 26 1.2E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L01_07200 37c2d137f95aac9c8ba6fac10b8f568a 190 PRINTS PR00686 Transcription initiation factor TFIID signature 35 54 1.2E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L01_07200 37c2d137f95aac9c8ba6fac10b8f568a 190 PRINTS PR00686 Transcription initiation factor TFIID signature 102 118 1.2E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L01_07200 37c2d137f95aac9c8ba6fac10b8f568a 190 PRINTS PR00686 Transcription initiation factor TFIID signature 144 160 1.2E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L01_07200 37c2d137f95aac9c8ba6fac10b8f568a 190 PRINTS PR00686 Transcription initiation factor TFIID signature 54 72 1.2E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L01_07200 37c2d137f95aac9c8ba6fac10b8f568a 190 Gene3D G3DSA:3.30.310.10 98 182 3.7E-35 T 23-10-2018 IPR012295 TBP domain superfamily A3L01_07200 37c2d137f95aac9c8ba6fac10b8f568a 190 SUPERFAMILY SSF55945 5 95 3.3E-29 T 23-10-2018 A3L01_07200 37c2d137f95aac9c8ba6fac10b8f568a 190 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 9 89 1.4E-27 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L01_07200 37c2d137f95aac9c8ba6fac10b8f568a 190 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 100 181 1.3E-28 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L01_07200 37c2d137f95aac9c8ba6fac10b8f568a 190 SUPERFAMILY SSF55945 96 182 2.2E-30 T 23-10-2018 A3L01_04965 06febf9d5eeb38099a47a09119a55d89 409 PIRSF PIRSF005243 4 408 7.9E-110 T 23-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 A3L01_04965 06febf9d5eeb38099a47a09119a55d89 409 SUPERFAMILY SSF52218 262 408 1.56E-30 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A3L01_04965 06febf9d5eeb38099a47a09119a55d89 409 SMART SM00849 39 209 7.0E-25 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_04965 06febf9d5eeb38099a47a09119a55d89 409 Pfam PF00753 Metallo-beta-lactamase superfamily 41 185 8.7E-6 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_04965 06febf9d5eeb38099a47a09119a55d89 409 SUPERFAMILY SSF56281 8 254 3.54E-43 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_04965 06febf9d5eeb38099a47a09119a55d89 409 Gene3D G3DSA:3.40.50.360 260 405 1.7E-28 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A3L01_04965 06febf9d5eeb38099a47a09119a55d89 409 Gene3D G3DSA:3.60.15.10 1 258 6.4E-88 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_09390 311f25400b8edd22797bace791a0730e 379 Gene3D G3DSA:3.40.50.2000 21 208 2.7E-23 T 23-10-2018 A3L01_09390 311f25400b8edd22797bace791a0730e 379 SUPERFAMILY SSF53756 24 379 1.05E-33 T 23-10-2018 A3L01_09390 311f25400b8edd22797bace791a0730e 379 Gene3D G3DSA:3.40.50.2000 209 364 1.1E-14 T 23-10-2018 A3L01_09390 311f25400b8edd22797bace791a0730e 379 Pfam PF13692 Glycosyl transferases group 1 224 340 1.1E-8 T 23-10-2018 A3L01_09390 311f25400b8edd22797bace791a0730e 379 Pfam PF13579 Glycosyl transferase 4-like domain 22 172 6.1E-12 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L01_05205 5e94126cf0c09a7bc557d85ba8ea508a 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 83 96 5.6E-6 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A3L01_05205 5e94126cf0c09a7bc557d85ba8ea508a 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 195 209 5.6E-6 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A3L01_05205 5e94126cf0c09a7bc557d85ba8ea508a 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 40 55 5.6E-6 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A3L01_05205 5e94126cf0c09a7bc557d85ba8ea508a 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 5.6E-6 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A3L01_05205 5e94126cf0c09a7bc557d85ba8ea508a 279 Pfam PF12146 Serine aminopeptidase, S33 14 240 1.2E-65 T 23-10-2018 IPR022742 Serine aminopeptidase, S33 A3L01_05205 5e94126cf0c09a7bc557d85ba8ea508a 279 Gene3D G3DSA:3.40.50.1820 1 261 2.3E-66 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L01_05205 5e94126cf0c09a7bc557d85ba8ea508a 279 SUPERFAMILY SSF53474 10 253 1.34E-47 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L01_04095 bda9e77a4877eda5c43b2db42dd9c54c 232 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 222 9.4E-64 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L01_04095 bda9e77a4877eda5c43b2db42dd9c54c 232 Gene3D G3DSA:3.40.50.1860 107 214 1.8E-87 T 23-10-2018 A3L01_04095 bda9e77a4877eda5c43b2db42dd9c54c 232 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 81 89 - T 23-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L01_04095 bda9e77a4877eda5c43b2db42dd9c54c 232 Gene3D G3DSA:3.40.50.1860 6 220 1.8E-87 T 23-10-2018 A3L01_04095 bda9e77a4877eda5c43b2db42dd9c54c 232 SUPERFAMILY SSF53681 4 117 8.18E-37 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L01_04095 bda9e77a4877eda5c43b2db42dd9c54c 232 SUPERFAMILY SSF53681 119 227 8.67E-27 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L01_04095 bda9e77a4877eda5c43b2db42dd9c54c 232 TIGRFAM TIGR00035 asp_race: aspartate racemase 3 229 2.9E-105 T 23-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 A3L01_01020 4807d82be44c9697ff7b314602627568 360 Pfam PF01637 ATPase domain predominantly from Archaea 14 250 2.3E-18 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L01_01020 4807d82be44c9697ff7b314602627568 360 Gene3D G3DSA:1.10.8.60 211 288 1.4E-26 T 23-10-2018 A3L01_01020 4807d82be44c9697ff7b314602627568 360 SUPERFAMILY SSF46785 287 358 1.72E-20 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_01020 4807d82be44c9697ff7b314602627568 360 SUPERFAMILY SSF52540 1 286 8.58E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_01020 4807d82be44c9697ff7b314602627568 360 Gene3D G3DSA:1.10.10.10 290 359 2.4E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_01020 4807d82be44c9697ff7b314602627568 360 Gene3D G3DSA:3.40.50.300 1 209 1.0E-40 T 23-10-2018 A3L01_00795 7aff1db0182eb0ef0b10a93b7fedc7b4 256 SMART SM00322 146 211 3.4E-9 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L01_00795 7aff1db0182eb0ef0b10a93b7fedc7b4 256 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 11 46 2.1E-7 T 23-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L01_00795 7aff1db0182eb0ef0b10a93b7fedc7b4 256 Gene3D G3DSA:2.40.50.140 58 142 4.9E-20 T 23-10-2018 A3L01_00795 7aff1db0182eb0ef0b10a93b7fedc7b4 256 Pfam PF15985 KH domain 149 195 1.3E-8 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A3L01_00795 7aff1db0182eb0ef0b10a93b7fedc7b4 256 SMART SM00316 63 137 1.6E-6 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L01_00795 7aff1db0182eb0ef0b10a93b7fedc7b4 256 SUPERFAMILY SSF54791 148 227 3.37E-18 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L01_00795 7aff1db0182eb0ef0b10a93b7fedc7b4 256 SUPERFAMILY SSF110324 3 58 5.23E-14 T 23-10-2018 A3L01_00795 7aff1db0182eb0ef0b10a93b7fedc7b4 256 Hamap MF_00623 Exosome complex component Rrp4 [rrp4]. 7 235 40.046 T 23-10-2018 IPR023474 Exosome complex component Rrp4 GO:0000178|GO:0008143 A3L01_00795 7aff1db0182eb0ef0b10a93b7fedc7b4 256 Gene3D G3DSA:2.40.50.100 1 57 1.6E-21 T 23-10-2018 A3L01_00795 7aff1db0182eb0ef0b10a93b7fedc7b4 256 SUPERFAMILY SSF50249 59 152 4.76E-18 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_00795 7aff1db0182eb0ef0b10a93b7fedc7b4 256 Gene3D G3DSA:3.30.1370.10 149 235 8.7E-34 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L01_03675 ff6562f4a69c82a0ab8a22ad11b819fb 259 Gene3D G3DSA:3.40.1210.10 3 258 7.4E-82 T 23-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A3L01_03675 ff6562f4a69c82a0ab8a22ad11b819fb 259 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 3 245 5.7E-70 T 23-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A3L01_03675 ff6562f4a69c82a0ab8a22ad11b819fb 259 SUPERFAMILY SSF64167 3 257 1.23E-71 T 23-10-2018 A3L01_03675 ff6562f4a69c82a0ab8a22ad11b819fb 259 Pfam PF01975 Survival protein SurE 4 195 1.3E-53 T 23-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A3L01_03675 ff6562f4a69c82a0ab8a22ad11b819fb 259 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 2 259 32.431 T 23-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A3L01_09930 9aef489916a8ec3e113960771548ba80 335 Gene3D G3DSA:3.40.50.300 3 335 1.2E-96 T 23-10-2018 A3L01_09930 9aef489916a8ec3e113960771548ba80 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 311 8.2E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L01_09930 9aef489916a8ec3e113960771548ba80 335 SMART SM00382 45 249 3.4E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_09930 9aef489916a8ec3e113960771548ba80 335 SUPERFAMILY SSF52540 5 263 1.5E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_09930 9aef489916a8ec3e113960771548ba80 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 331 1.6E-28 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L01_09930 9aef489916a8ec3e113960771548ba80 335 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_09930 9aef489916a8ec3e113960771548ba80 335 Pfam PF00005 ABC transporter 37 191 7.8E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_06480 b01ec5031f2f99ca767cf5bd4d5e7a00 187 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 187 89.931 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 A3L01_06480 b01ec5031f2f99ca767cf5bd4d5e7a00 187 Gene3D G3DSA:3.40.50.620 1 178 3.7E-54 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_06480 b01ec5031f2f99ca767cf5bd4d5e7a00 187 Pfam PF01467 Cytidylyltransferase-like 6 136 2.2E-18 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L01_06480 b01ec5031f2f99ca767cf5bd4d5e7a00 187 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 64 1.1E-18 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L01_06480 b01ec5031f2f99ca767cf5bd4d5e7a00 187 SUPERFAMILY SSF52374 3 166 4.74E-37 T 23-10-2018 A3L01_06480 b01ec5031f2f99ca767cf5bd4d5e7a00 187 TIGRFAM TIGR01527 arch_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 4 168 7.1E-69 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 A3L01_07615 c1423c4808ba16d4a4df21f334000d64 261 Gene3D G3DSA:3.30.2010.10 48 132 3.3E-19 T 23-10-2018 A3L01_07615 c1423c4808ba16d4a4df21f334000d64 261 Pfam PF01435 Peptidase family M48 56 244 7.6E-19 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A3L01_04280 bd2a0246953af9a846c6841dbd74138a 210 SUPERFAMILY SSF52499 17 207 2.35E-46 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A3L01_04280 bd2a0246953af9a846c6841dbd74138a 210 Pfam PF00857 Isochorismatase family 34 196 6.7E-37 T 23-10-2018 IPR000868 Isochorismatase-like GO:0003824 A3L01_04280 bd2a0246953af9a846c6841dbd74138a 210 Gene3D G3DSA:3.40.50.850 12 205 2.7E-44 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A3L01_00840 684d5322f0a1b7732863d22283f07ab7 281 Gene3D G3DSA:3.10.580.10 1 122 4.0E-39 T 23-10-2018 A3L01_00840 684d5322f0a1b7732863d22283f07ab7 281 Gene3D G3DSA:3.10.580.10 123 281 4.7E-36 T 23-10-2018 A3L01_00840 684d5322f0a1b7732863d22283f07ab7 281 SMART SM00116 136 184 2.1 T 23-10-2018 IPR000644 CBS domain A3L01_00840 684d5322f0a1b7732863d22283f07ab7 281 SMART SM00116 10 59 2.4E-4 T 23-10-2018 IPR000644 CBS domain A3L01_00840 684d5322f0a1b7732863d22283f07ab7 281 SMART SM00116 231 279 1.5E-10 T 23-10-2018 IPR000644 CBS domain A3L01_00840 684d5322f0a1b7732863d22283f07ab7 281 SMART SM00116 70 118 2.5E-9 T 23-10-2018 IPR000644 CBS domain A3L01_00840 684d5322f0a1b7732863d22283f07ab7 281 SUPERFAMILY SSF54631 124 278 9.27E-32 T 23-10-2018 A3L01_00840 684d5322f0a1b7732863d22283f07ab7 281 Pfam PF00571 CBS domain 137 181 8.3E-5 T 23-10-2018 IPR000644 CBS domain A3L01_00840 684d5322f0a1b7732863d22283f07ab7 281 Pfam PF00571 CBS domain 3 55 7.0E-8 T 23-10-2018 IPR000644 CBS domain A3L01_00840 684d5322f0a1b7732863d22283f07ab7 281 Pfam PF00571 CBS domain 68 116 1.8E-11 T 23-10-2018 IPR000644 CBS domain A3L01_00840 684d5322f0a1b7732863d22283f07ab7 281 Pfam PF00571 CBS domain 224 279 3.0E-13 T 23-10-2018 IPR000644 CBS domain A3L01_00840 684d5322f0a1b7732863d22283f07ab7 281 SUPERFAMILY SSF54631 1 118 1.89E-27 T 23-10-2018 A3L01_05440 4fa775f7dd0327d7ff6dfdeca5823708 464 Pfam PF03008 Archaea bacterial proteins of unknown function 318 414 1.3E-26 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L01_05440 4fa775f7dd0327d7ff6dfdeca5823708 464 Pfam PF01637 ATPase domain predominantly from Archaea 6 208 1.8E-26 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L01_05440 4fa775f7dd0327d7ff6dfdeca5823708 464 SUPERFAMILY SSF52540 4 248 4.04E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_05440 4fa775f7dd0327d7ff6dfdeca5823708 464 Gene3D G3DSA:1.10.10.10 246 322 6.6E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_05440 4fa775f7dd0327d7ff6dfdeca5823708 464 Gene3D G3DSA:3.40.50.300 1 173 1.5E-32 T 23-10-2018 A3L01_05440 4fa775f7dd0327d7ff6dfdeca5823708 464 Pfam PF09339 IclR helix-turn-helix domain 249 292 2.2E-7 T 23-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A3L01_05440 4fa775f7dd0327d7ff6dfdeca5823708 464 SUPERFAMILY SSF46785 247 325 6.5E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_07255 6ada0586dfee5a0cee4c29c5f4cc28d6 424 Pfam PF01798 snoRNA binding domain, fibrillarin 138 363 8.2E-73 T 23-10-2018 IPR002687 Nop domain A3L01_07255 6ada0586dfee5a0cee4c29c5f4cc28d6 424 SMART SM00931 130 182 2.0E-26 T 23-10-2018 IPR012976 NOSIC A3L01_07255 6ada0586dfee5a0cee4c29c5f4cc28d6 424 SUPERFAMILY SSF89124 126 366 3.4E-81 T 23-10-2018 IPR036070 Nop domain superfamily A3L01_07255 6ada0586dfee5a0cee4c29c5f4cc28d6 424 Gene3D G3DSA:1.10.287.660 131 243 7.2E-39 T 23-10-2018 IPR029012 Helix hairpin bin domain superfamily A3L01_07255 6ada0586dfee5a0cee4c29c5f4cc28d6 424 Gene3D G3DSA:1.10.150.460 161 212 7.2E-39 T 23-10-2018 A3L01_07255 6ada0586dfee5a0cee4c29c5f4cc28d6 424 Gene3D G3DSA:3.30.420.220 1 125 5.2E-49 T 23-10-2018 A3L01_07255 6ada0586dfee5a0cee4c29c5f4cc28d6 424 Gene3D G3DSA:1.10.246.90 244 368 5.5E-52 T 23-10-2018 A3L01_08250 a5d6221c9533abaa95567657ff7e6658 300 ProSitePatterns PS01215 Mrp family signature. 146 162 - T 23-10-2018 IPR000808 Mrp, conserved site GO:0005524 A3L01_08250 a5d6221c9533abaa95567657ff7e6658 300 Hamap MF_02040 Iron-sulfur cluster carrier protein. 20 282 37.115 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein A3L01_08250 a5d6221c9533abaa95567657ff7e6658 300 Gene3D G3DSA:3.40.50.300 17 281 1.1E-81 T 23-10-2018 A3L01_08250 a5d6221c9533abaa95567657ff7e6658 300 SUPERFAMILY SSF52540 19 266 1.19E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_08250 a5d6221c9533abaa95567657ff7e6658 300 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 30 281 5.3E-96 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 A3L01_02500 14222d0959c3f471cb910f6bd77f066e 419 SUPERFAMILY SSF51161 243 409 1.07E-38 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A3L01_02500 14222d0959c3f471cb910f6bd77f066e 419 Gene3D G3DSA:3.90.550.10 1 219 1.7E-48 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_02500 14222d0959c3f471cb910f6bd77f066e 419 Gene3D G3DSA:2.160.10.10 220 410 4.4E-58 T 23-10-2018 A3L01_02500 14222d0959c3f471cb910f6bd77f066e 419 SUPERFAMILY SSF53448 2 312 1.92E-68 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_02500 14222d0959c3f471cb910f6bd77f066e 419 TIGRFAM TIGR03992 Arch_glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 2 398 1.2E-151 T 23-10-2018 IPR023915 UDP-GlcNAc diphosphorylase/GlcNAc-1-P N-acetyltransferase, GlmU, archaeal-type GO:0003977|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 A3L01_02500 14222d0959c3f471cb910f6bd77f066e 419 Pfam PF00483 Nucleotidyl transferase 2 232 5.5E-38 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L01_02500 14222d0959c3f471cb910f6bd77f066e 419 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 254 287 1.2E-9 T 23-10-2018 IPR001451 Hexapeptide repeat A3L01_02500 14222d0959c3f471cb910f6bd77f066e 419 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 365 398 7.5E-6 T 23-10-2018 IPR001451 Hexapeptide repeat A3L01_02215 e100e1179a504f89d5774edf5c0b8d34 768 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 46 411 3.5E-109 T 23-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ A3L01_02215 e100e1179a504f89d5774edf5c0b8d34 768 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 462 688 2.0E-27 T 23-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit A3L01_02215 e100e1179a504f89d5774edf5c0b8d34 768 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 143 450 3.5E-56 T 23-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit A3L01_03925 2d56d9dd2e20f9d70c3f1a931a932835 275 Gene3D G3DSA:3.40.50.10470 96 275 8.4E-63 T 23-10-2018 A3L01_03925 2d56d9dd2e20f9d70c3f1a931a932835 275 SUPERFAMILY SSF100950 4 272 9.57E-68 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L01_03925 2d56d9dd2e20f9d70c3f1a931a932835 275 Gene3D G3DSA:1.20.120.420 1 95 1.1E-30 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L01_03925 2d56d9dd2e20f9d70c3f1a931a932835 275 Pfam PF01008 Initiation factor 2 subunit family 18 271 3.6E-51 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A3L01_03960 982e854281c6ec5cd840dec5dd4094c3 570 Gene3D G3DSA:1.10.30.30 363 426 2.1E-141 T 23-10-2018 A3L01_03960 982e854281c6ec5cd840dec5dd4094c3 570 Hamap MF_00253_A Glycine--tRNA ligase [glyQS]. 6 568 47.053 T 23-10-2018 IPR022960 Glycine-tRNA ligase, archaeal GO:0004820 KEGG: 00970+6.1.1.14 A3L01_03960 982e854281c6ec5cd840dec5dd4094c3 570 Pfam PF03129 Anticodon binding domain 475 565 2.6E-23 T 23-10-2018 IPR004154 Anticodon-binding A3L01_03960 982e854281c6ec5cd840dec5dd4094c3 570 SUPERFAMILY SSF55681 7 478 5.49E-117 T 23-10-2018 A3L01_03960 982e854281c6ec5cd840dec5dd4094c3 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 435 447 1.0E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L01_03960 982e854281c6ec5cd840dec5dd4094c3 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 513 532 1.0E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L01_03960 982e854281c6ec5cd840dec5dd4094c3 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 193 210 1.0E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L01_03960 982e854281c6ec5cd840dec5dd4094c3 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 210 220 1.0E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L01_03960 982e854281c6ec5cd840dec5dd4094c3 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 27 41 1.0E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L01_03960 982e854281c6ec5cd840dec5dd4094c3 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 142 154 1.0E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L01_03960 982e854281c6ec5cd840dec5dd4094c3 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 161 178 1.0E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L01_03960 982e854281c6ec5cd840dec5dd4094c3 570 Gene3D G3DSA:1.20.1430.20 84 147 2.1E-141 T 23-10-2018 A3L01_03960 982e854281c6ec5cd840dec5dd4094c3 570 SUPERFAMILY SSF52954 462 567 1.66E-32 T 23-10-2018 A3L01_03960 982e854281c6ec5cd840dec5dd4094c3 570 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 158 243 6.7E-11 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_03960 982e854281c6ec5cd840dec5dd4094c3 570 Gene3D G3DSA:3.40.50.800 473 570 7.0E-32 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A3L01_03960 982e854281c6ec5cd840dec5dd4094c3 570 Gene3D G3DSA:3.30.930.10 14 458 2.1E-141 T 23-10-2018 A3L01_03960 982e854281c6ec5cd840dec5dd4094c3 570 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 7 565 2.1E-219 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L01_01560 6c4edb80ec6a2c3bbcac4fb513d4f205 444 Pfam PF03551 Transcriptional regulator PadR-like family 377 440 1.3E-9 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L01_01560 6c4edb80ec6a2c3bbcac4fb513d4f205 444 Gene3D G3DSA:3.40.50.1100 96 192 4.6E-97 T 23-10-2018 A3L01_01560 6c4edb80ec6a2c3bbcac4fb513d4f205 444 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 62 353 2.5E-60 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L01_01560 6c4edb80ec6a2c3bbcac4fb513d4f205 444 Gene3D G3DSA:3.40.50.1100 49 358 4.6E-97 T 23-10-2018 A3L01_01560 6c4edb80ec6a2c3bbcac4fb513d4f205 444 Gene3D G3DSA:1.10.10.10 359 444 9.2E-15 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_01560 6c4edb80ec6a2c3bbcac4fb513d4f205 444 SMART SM00418 366 444 1.6E-12 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_01560 6c4edb80ec6a2c3bbcac4fb513d4f205 444 SUPERFAMILY SSF46785 373 442 5.96E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_01560 6c4edb80ec6a2c3bbcac4fb513d4f205 444 SUPERFAMILY SSF53686 5 358 2.62E-71 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L01_01670 aec0fcae1726cc5cc1d97e9fdc9c5f93 336 Pfam PF00586 AIR synthase related protein, N-terminal domain 40 149 1.0E-17 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L01_01670 aec0fcae1726cc5cc1d97e9fdc9c5f93 336 SUPERFAMILY SSF55326 4 153 1.14E-32 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L01_01670 aec0fcae1726cc5cc1d97e9fdc9c5f93 336 Pfam PF02769 AIR synthase related protein, C-terminal domain 160 314 4.4E-31 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L01_01670 aec0fcae1726cc5cc1d97e9fdc9c5f93 336 PIRSF PIRSF005644 1 336 3.0E-125 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A3L01_01670 aec0fcae1726cc5cc1d97e9fdc9c5f93 336 Gene3D G3DSA:3.30.1330.10 1 153 8.8E-45 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L01_01670 aec0fcae1726cc5cc1d97e9fdc9c5f93 336 SUPERFAMILY SSF56042 155 330 3.74E-47 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L01_01670 aec0fcae1726cc5cc1d97e9fdc9c5f93 336 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 2 336 1.9E-120 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A3L01_01670 aec0fcae1726cc5cc1d97e9fdc9c5f93 336 Gene3D G3DSA:3.90.650.10 154 336 1.5E-54 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L01_09820 bcb237c5506287b97a6e900fb80d4b9b 658 Gene3D G3DSA:1.20.1460.20 47 290 2.7E-24 T 23-10-2018 A3L01_09820 bcb237c5506287b97a6e900fb80d4b9b 658 Gene3D G3DSA:3.30.70.2750 149 224 2.7E-24 T 23-10-2018 A3L01_09820 bcb237c5506287b97a6e900fb80d4b9b 658 Gene3D G3DSA:3.30.70.2170 7 309 2.7E-24 T 23-10-2018 A3L01_09820 bcb237c5506287b97a6e900fb80d4b9b 658 Pfam PF01496 V-type ATPase 116kDa subunit family 151 441 3.7E-24 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L01_09820 bcb237c5506287b97a6e900fb80d4b9b 658 Pfam PF01496 V-type ATPase 116kDa subunit family 554 646 6.6E-12 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L01_05960 e94d5e8aa8d5305f8dbe6310f374d6ed 346 Pfam PF13685 Iron-containing alcohol dehydrogenase 13 268 9.8E-72 T 23-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A3L01_05960 e94d5e8aa8d5305f8dbe6310f374d6ed 346 Hamap MF_00497_A Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 3 346 46.538 T 23-10-2018 IPR023002 Glycerol-1-phosphate dehydrogenase, archaea GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A3L01_05960 e94d5e8aa8d5305f8dbe6310f374d6ed 346 SUPERFAMILY SSF56796 1 339 1.57E-73 T 23-10-2018 A3L01_05960 e94d5e8aa8d5305f8dbe6310f374d6ed 346 Gene3D G3DSA:3.40.50.1970 1 155 3.7E-34 T 23-10-2018 A3L01_05960 e94d5e8aa8d5305f8dbe6310f374d6ed 346 PIRSF PIRSF000112 1 343 5.1E-66 T 23-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A3L01_05960 e94d5e8aa8d5305f8dbe6310f374d6ed 346 Gene3D G3DSA:1.20.1090.10 156 345 1.1E-66 T 23-10-2018 A3L01_02425 dc8833d835550334e5bfda7a26b2c1b7 245 SUPERFAMILY SSF56784 4 225 6.96E-40 T 23-10-2018 IPR036412 HAD-like superfamily A3L01_02425 dc8833d835550334e5bfda7a26b2c1b7 245 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 4 219 2.1E-72 T 23-10-2018 A3L01_02425 dc8833d835550334e5bfda7a26b2c1b7 245 Pfam PF08282 haloacid dehalogenase-like hydrolase 141 219 7.8E-18 T 23-10-2018 A3L01_02425 dc8833d835550334e5bfda7a26b2c1b7 245 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 85 7.8E-8 T 23-10-2018 A3L01_02425 dc8833d835550334e5bfda7a26b2c1b7 245 Gene3D G3DSA:3.40.50.1000 4 222 9.2E-73 T 23-10-2018 IPR023214 HAD superfamily A3L01_02425 dc8833d835550334e5bfda7a26b2c1b7 245 Hamap MF_01419 Phosphoglycolate phosphatase. 3 229 31.712 T 23-10-2018 IPR006382 Phosphoglycolate phosphatase GO:0000287|GO:0008967|GO:0016311 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 A3L01_02425 dc8833d835550334e5bfda7a26b2c1b7 245 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 6 232 5.6E-68 T 23-10-2018 A3L01_02425 dc8833d835550334e5bfda7a26b2c1b7 245 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 197 2.9E-13 T 23-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A3L01_02425 dc8833d835550334e5bfda7a26b2c1b7 245 Gene3D G3DSA:3.90.1070.10 86 153 9.2E-73 T 23-10-2018 A3L01_08185 879249801b42b8d797fbd58e9e5c27d7 105 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 33 104 1.1E-33 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 A3L01_08185 879249801b42b8d797fbd58e9e5c27d7 105 Pfam PF14697 4Fe-4S dicluster domain 47 100 3.0E-11 T 23-10-2018 A3L01_08185 879249801b42b8d797fbd58e9e5c27d7 105 SUPERFAMILY SSF54862 33 104 1.31E-24 T 23-10-2018 A3L01_08185 879249801b42b8d797fbd58e9e5c27d7 105 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_08185 879249801b42b8d797fbd58e9e5c27d7 105 Gene3D G3DSA:3.30.70.20 35 68 1.6E-5 T 23-10-2018 A3L01_08185 879249801b42b8d797fbd58e9e5c27d7 105 Gene3D G3DSA:3.30.70.20 69 105 1.5E-9 T 23-10-2018 A3L01_03760 b2ddcfa27c14e9255f8a92d9dac0108d 614 Pfam PF00326 Prolyl oligopeptidase family 412 613 1.1E-54 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A3L01_03760 b2ddcfa27c14e9255f8a92d9dac0108d 614 SUPERFAMILY SSF50993 2 352 1.15E-37 T 23-10-2018 A3L01_03760 b2ddcfa27c14e9255f8a92d9dac0108d 614 SUPERFAMILY SSF53474 369 612 2.45E-50 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L01_03760 b2ddcfa27c14e9255f8a92d9dac0108d 614 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 2 352 9.5E-16 T 23-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 A3L01_03760 b2ddcfa27c14e9255f8a92d9dac0108d 614 Gene3D G3DSA:2.130.10.120 49 362 6.2E-133 T 23-10-2018 A3L01_03760 b2ddcfa27c14e9255f8a92d9dac0108d 614 Gene3D G3DSA:3.40.50.1820 2 610 6.2E-133 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L01_03760 b2ddcfa27c14e9255f8a92d9dac0108d 614 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 475 495 2.6E-53 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L01_03760 b2ddcfa27c14e9255f8a92d9dac0108d 614 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 530 545 2.6E-53 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L01_03760 b2ddcfa27c14e9255f8a92d9dac0108d 614 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 449 468 2.6E-53 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L01_03760 b2ddcfa27c14e9255f8a92d9dac0108d 614 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 395 413 2.6E-53 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L01_03760 b2ddcfa27c14e9255f8a92d9dac0108d 614 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 548 570 2.6E-53 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L01_03760 b2ddcfa27c14e9255f8a92d9dac0108d 614 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 421 445 2.6E-53 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L01_02095 30ae7415a973c2759bf7c664cfcdffb0 207 SUPERFAMILY SSF52540 2 201 3.72E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_02095 30ae7415a973c2759bf7c664cfcdffb0 207 ProSitePatterns PS01331 Thymidylate kinase signature. 98 110 - T 23-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A3L01_02095 30ae7415a973c2759bf7c664cfcdffb0 207 Gene3D G3DSA:3.40.50.300 1 204 1.7E-68 T 23-10-2018 A3L01_02095 30ae7415a973c2759bf7c664cfcdffb0 207 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 196 3.4E-58 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A3L01_02095 30ae7415a973c2759bf7c664cfcdffb0 207 Pfam PF02223 Thymidylate kinase 7 196 2.1E-54 T 23-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A3L01_02095 30ae7415a973c2759bf7c664cfcdffb0 207 Hamap MF_00165 Thymidylate kinase [tmk]. 3 204 27.99 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A3L01_06910 70efb39df289a13351d4b469e984f9ef 414 SUPERFAMILY SSF55307 238 352 7.55E-35 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A3L01_06910 70efb39df289a13351d4b469e984f9ef 414 SUPERFAMILY SSF52490 36 239 5.63E-57 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L01_06910 70efb39df289a13351d4b469e984f9ef 414 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 31 356 1.0E-112 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A3L01_06910 70efb39df289a13351d4b469e984f9ef 414 SMART SM00865 238 355 3.4E-38 T 23-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 A3L01_06910 70efb39df289a13351d4b469e984f9ef 414 Gene3D G3DSA:3.40.50.1440 35 347 3.4E-99 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L01_06910 70efb39df289a13351d4b469e984f9ef 414 ProSitePatterns PS01134 FtsZ protein signature 1. 68 102 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A3L01_06910 70efb39df289a13351d4b469e984f9ef 414 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 37 205 4.8E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L01_06910 70efb39df289a13351d4b469e984f9ef 414 Pfam PF12327 FtsZ family, C-terminal domain 253 347 1.8E-24 T 23-10-2018 IPR024757 Cell division protein FtsZ, C-terminal A3L01_06910 70efb39df289a13351d4b469e984f9ef 414 SMART SM00864 37 236 4.3E-85 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L01_06910 70efb39df289a13351d4b469e984f9ef 414 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 33 383 33.654 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A3L01_06910 70efb39df289a13351d4b469e984f9ef 414 PRINTS PR00423 Cell division protein FtsZ signature 122 142 7.2E-36 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L01_06910 70efb39df289a13351d4b469e984f9ef 414 PRINTS PR00423 Cell division protein FtsZ signature 220 242 7.2E-36 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L01_06910 70efb39df289a13351d4b469e984f9ef 414 PRINTS PR00423 Cell division protein FtsZ signature 243 264 7.2E-36 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L01_06910 70efb39df289a13351d4b469e984f9ef 414 PRINTS PR00423 Cell division protein FtsZ signature 158 179 7.2E-36 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L01_06910 70efb39df289a13351d4b469e984f9ef 414 ProSitePatterns PS01135 FtsZ protein signature 2. 121 142 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A3L01_05250 d5b83dd0e5745dcd4f447b9f8ecce786 143 Pfam PF04191 Phospholipid methyltransferase 63 127 6.1E-5 T 23-10-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 A3L01_05250 d5b83dd0e5745dcd4f447b9f8ecce786 143 Gene3D G3DSA:1.20.120.1630 4 143 4.9E-24 T 23-10-2018 A3L01_01095 4b00cfd1028a78c37c2695f05fe38d0a 243 Gene3D G3DSA:2.40.50.740 123 177 8.9E-17 T 23-10-2018 IPR038237 Ribosomal protein S4e, central domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01095 4b00cfd1028a78c37c2695f05fe38d0a 243 Pfam PF01479 S4 domain 45 91 1.1E-13 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01095 4b00cfd1028a78c37c2695f05fe38d0a 243 Gene3D G3DSA:3.10.290.40 1 118 6.6E-50 T 23-10-2018 A3L01_01095 4b00cfd1028a78c37c2695f05fe38d0a 243 SMART SM00363 44 107 4.1E-10 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01095 4b00cfd1028a78c37c2695f05fe38d0a 243 ProDom PD002667 RIBOSOMAL RIBONUCLEOPROTEIN RNA-BINDING 40S S4 S4 S4E 30S ISOFORM X 88 182 2.0E-41 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01095 4b00cfd1028a78c37c2695f05fe38d0a 243 SUPERFAMILY SSF55174 52 96 4.58E-8 T 23-10-2018 A3L01_01095 4b00cfd1028a78c37c2695f05fe38d0a 243 Hamap MF_00485 30S ribosomal protein S4e [rps4e]. 8 242 43.054 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01095 4b00cfd1028a78c37c2695f05fe38d0a 243 Pfam PF00900 Ribosomal family S4e 96 173 3.1E-22 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01095 4b00cfd1028a78c37c2695f05fe38d0a 243 Gene3D G3DSA:2.30.30.30 179 243 4.2E-18 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L01_01095 4b00cfd1028a78c37c2695f05fe38d0a 243 ProSitePatterns PS00528 Ribosomal protein S4e signature. 9 23 - T 23-10-2018 IPR018199 Ribosomal protein S4e, N-terminal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01095 4b00cfd1028a78c37c2695f05fe38d0a 243 PIRSF PIRSF002116 2 243 5.4E-101 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01095 4b00cfd1028a78c37c2695f05fe38d0a 243 Pfam PF08071 RS4NT (NUC023) domain 4 40 5.3E-17 T 23-10-2018 IPR013843 Ribosomal protein S4e, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01205 d1b2474e930155336aaf856c61329b9a 180 SMART SM01390 5 102 2.6E-7 T 23-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A3L01_01205 d1b2474e930155336aaf856c61329b9a 180 SMART SM00363 103 165 1.5E-14 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01205 d1b2474e930155336aaf856c61329b9a 180 Hamap MF_01306_A 30S ribosomal protein S4 [rpsD]. 1 156 34.361 T 23-10-2018 IPR022802 Ribosomal protein S4, archaeal GO:0006412|GO:0019843 A3L01_01205 d1b2474e930155336aaf856c61329b9a 180 Gene3D G3DSA:3.10.290.10 104 177 1.2E-16 T 23-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A3L01_01205 d1b2474e930155336aaf856c61329b9a 180 ProSitePatterns PS00632 Ribosomal protein S4 signature. 101 125 - T 23-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01205 d1b2474e930155336aaf856c61329b9a 180 Pfam PF01479 S4 domain 103 148 3.4E-17 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01205 d1b2474e930155336aaf856c61329b9a 180 TIGRFAM TIGR01018 uS4_arch: ribosomal protein uS4 1 161 7.0E-76 T 23-10-2018 IPR005710 Ribosomal protein S4/S9, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01205 d1b2474e930155336aaf856c61329b9a 180 SUPERFAMILY SSF55174 9 160 7.79E-33 T 23-10-2018 A3L01_10025 a494c4197126de9faa96bc357f234b8e 251 SUPERFAMILY SSF53335 8 233 3.28E-26 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_10025 a494c4197126de9faa96bc357f234b8e 251 Gene3D G3DSA:3.40.50.150 66 249 1.3E-41 T 23-10-2018 A3L01_10025 a494c4197126de9faa96bc357f234b8e 251 Pfam PF05971 Protein of unknown function (DUF890) 18 164 7.7E-9 T 23-10-2018 IPR010286 Ribosomal RNA large subunit methyltransferase F-like GO:0008168 A3L01_03730 f6f02f84ee15121bb18a1f363bae85bc 215 Pfam PF00156 Phosphoribosyl transferase domain 16 152 1.7E-20 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L01_03730 f6f02f84ee15121bb18a1f363bae85bc 215 SUPERFAMILY SSF53271 7 163 1.84E-36 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L01_03730 f6f02f84ee15121bb18a1f363bae85bc 215 Gene3D G3DSA:3.40.50.2020 6 181 1.1E-41 T 23-10-2018 A3L01_09115 e94d742dc4fdd5ceea056fa92f4ffb2f 148 Gene3D G3DSA:2.40.50.90 19 145 5.9E-21 T 23-10-2018 IPR035437 SNase-like, OB-fold superfamily A3L01_09115 e94d742dc4fdd5ceea056fa92f4ffb2f 148 Pfam PF00565 Staphylococcal nuclease homologue 51 137 3.2E-10 T 23-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 A3L01_09115 e94d742dc4fdd5ceea056fa92f4ffb2f 148 ProSitePatterns PS01284 Thermonuclease family signature 2. 96 106 - T 23-10-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 A3L01_09115 e94d742dc4fdd5ceea056fa92f4ffb2f 148 SUPERFAMILY SSF50199 23 140 2.88E-22 T 23-10-2018 A3L01_09115 e94d742dc4fdd5ceea056fa92f4ffb2f 148 SMART SM00318 21 144 5.8E-9 T 23-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 A3L01_07420 973262cd695498f2ed6fe891722bef43 581 SUPERFAMILY SSF56219 351 580 3.4E-31 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A3L01_07420 973262cd695498f2ed6fe891722bef43 581 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 371 571 1.5E-5 T 23-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase A3L01_07420 973262cd695498f2ed6fe891722bef43 581 Gene3D G3DSA:3.60.10.10 353 581 1.0E-31 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A3L01_08330 a02aa0b2d1e1c6f76d1edf166d60b40f 495 PIRSF PIRSF000538 4 494 2.6E-178 T 23-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A3L01_08330 a02aa0b2d1e1c6f76d1edf166d60b40f 495 Gene3D G3DSA:3.30.420.40 250 494 2.0E-91 T 23-10-2018 A3L01_08330 a02aa0b2d1e1c6f76d1edf166d60b40f 495 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 23-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A3L01_08330 a02aa0b2d1e1c6f76d1edf166d60b40f 495 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 357 377 - T 23-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A3L01_08330 a02aa0b2d1e1c6f76d1edf166d60b40f 495 Hamap MF_00186 Glycerol kinase [glpK]. 4 490 57.595 T 23-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A3L01_08330 a02aa0b2d1e1c6f76d1edf166d60b40f 495 SUPERFAMILY SSF53067 6 250 5.88E-96 T 23-10-2018 A3L01_08330 a02aa0b2d1e1c6f76d1edf166d60b40f 495 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 258 443 2.1E-52 T 23-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A3L01_08330 a02aa0b2d1e1c6f76d1edf166d60b40f 495 Gene3D G3DSA:3.30.420.40 4 249 4.9E-115 T 23-10-2018 A3L01_08330 a02aa0b2d1e1c6f76d1edf166d60b40f 495 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 5 489 7.7E-216 T 23-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A3L01_08330 a02aa0b2d1e1c6f76d1edf166d60b40f 495 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 248 6.7E-88 T 23-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A3L01_08330 a02aa0b2d1e1c6f76d1edf166d60b40f 495 SUPERFAMILY SSF53067 251 489 1.38E-81 T 23-10-2018 A3L01_03125 24a95b5d482a5b05ae413393672555c2 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 1.1E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_03125 24a95b5d482a5b05ae413393672555c2 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 1.1E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_03125 24a95b5d482a5b05ae413393672555c2 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 1.1E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_03125 24a95b5d482a5b05ae413393672555c2 153 Pfam PF13404 AsnC-type helix-turn-helix domain 7 47 6.2E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_03125 24a95b5d482a5b05ae413393672555c2 153 SUPERFAMILY SSF54909 67 144 2.15E-17 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L01_03125 24a95b5d482a5b05ae413393672555c2 153 SMART SM00344 7 113 1.6E-43 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L01_03125 24a95b5d482a5b05ae413393672555c2 153 Gene3D G3DSA:1.10.10.10 4 58 5.9E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_03125 24a95b5d482a5b05ae413393672555c2 153 SUPERFAMILY SSF46785 7 76 1.08E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_03125 24a95b5d482a5b05ae413393672555c2 153 Pfam PF01037 Lrp/AsnC ligand binding domain 73 142 1.3E-15 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L01_03125 24a95b5d482a5b05ae413393672555c2 153 Gene3D G3DSA:3.30.70.920 59 148 1.0E-21 T 23-10-2018 A3L01_01235 a11d664672ac69051cde913b928aff15 135 TIGRFAM TIGR03627 uS9_arch: ribosomal protein uS9 3 135 6.3E-62 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01235 a11d664672ac69051cde913b928aff15 135 Hamap MF_00532_A 30S ribosomal protein S9 [rpsI]. 3 135 37.194 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01235 a11d664672ac69051cde913b928aff15 135 ProSitePatterns PS00360 Ribosomal protein S9 signature. 68 86 - T 23-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 A3L01_01235 a11d664672ac69051cde913b928aff15 135 Pfam PF00380 Ribosomal protein S9/S16 8 135 1.4E-30 T 23-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 A3L01_01235 a11d664672ac69051cde913b928aff15 135 SUPERFAMILY SSF54211 3 135 5.31E-34 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L01_01235 a11d664672ac69051cde913b928aff15 135 Gene3D G3DSA:3.30.230.10 1 135 5.3E-51 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L01_03670 a05069f7f14a7b4f1ec1189b67fbed7a 324 SMART SM00729 17 247 3.6E-25 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L01_03670 a05069f7f14a7b4f1ec1189b67fbed7a 324 PIRSF PIRSF004954 1 319 1.9E-99 T 23-10-2018 IPR005909 Conserved hypothetical protein CHP01210 A3L01_03670 a05069f7f14a7b4f1ec1189b67fbed7a 324 TIGRFAM TIGR01210 TIGR01210: radical SAM enzyme, TIGR01210 family 3 321 4.8E-123 T 23-10-2018 IPR005909 Conserved hypothetical protein CHP01210 A3L01_03670 a05069f7f14a7b4f1ec1189b67fbed7a 324 SUPERFAMILY SSF102114 17 255 2.49E-16 T 23-10-2018 A3L01_03670 a05069f7f14a7b4f1ec1189b67fbed7a 324 Pfam PF04055 Radical SAM superfamily 33 180 1.2E-8 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L01_07340 785680c9a10e7ad4f0301b1979b58be3 388 Pfam PF02824 TGS domain 315 386 4.5E-24 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A3L01_07340 785680c9a10e7ad4f0301b1979b58be3 388 Gene3D G3DSA:3.10.20.30 312 388 8.2E-29 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L01_07340 785680c9a10e7ad4f0301b1979b58be3 388 SUPERFAMILY SSF81271 309 386 9.94E-19 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A3L01_07340 785680c9a10e7ad4f0301b1979b58be3 388 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 83 190 3.4E-13 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L01_07340 785680c9a10e7ad4f0301b1979b58be3 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 85 105 8.2E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_07340 785680c9a10e7ad4f0301b1979b58be3 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 106 124 8.2E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_07340 785680c9a10e7ad4f0301b1979b58be3 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 150 168 8.2E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_07340 785680c9a10e7ad4f0301b1979b58be3 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 133 148 8.2E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_07340 785680c9a10e7ad4f0301b1979b58be3 388 Pfam PF16897 C-terminal region of MMR_HSR1 domain 206 310 3.3E-18 T 23-10-2018 IPR031662 GTP binding protein, second domain A3L01_07340 785680c9a10e7ad4f0301b1979b58be3 388 Gene3D G3DSA:3.40.50.300 72 204 1.7E-33 T 23-10-2018 A3L01_07340 785680c9a10e7ad4f0301b1979b58be3 388 Pfam PF01926 50S ribosome-binding GTPase 84 185 5.1E-21 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_07340 785680c9a10e7ad4f0301b1979b58be3 388 Gene3D G3DSA:3.40.50.300 208 311 6.4E-9 T 23-10-2018 A3L01_07340 785680c9a10e7ad4f0301b1979b58be3 388 SUPERFAMILY SSF52540 84 323 1.34E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_01585 f16fa48c9496d6462626093b15d37523 484 PIRSF PIRSF006603 2 478 2.5E-157 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L01_01585 f16fa48c9496d6462626093b15d37523 484 Pfam PF01554 MatE 253 414 1.4E-26 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L01_01585 f16fa48c9496d6462626093b15d37523 484 Pfam PF01554 MatE 28 188 4.0E-32 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L01_01585 f16fa48c9496d6462626093b15d37523 484 TIGRFAM TIGR00797 matE: MATE efflux family protein 28 419 2.2E-74 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L01_06775 c36896ab2200d31d0acf2d75d37feb9a 67 Hamap MF_00511 30S ribosomal protein S17e [rps17e]. 1 63 22.128 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06775 c36896ab2200d31d0acf2d75d37feb9a 67 ProSitePatterns PS00712 Ribosomal protein S17e signature. 41 56 - T 23-10-2018 IPR018273 Ribosomal protein S17e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06775 c36896ab2200d31d0acf2d75d37feb9a 67 Gene3D G3DSA:1.10.60.20 1 62 1.8E-29 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06775 c36896ab2200d31d0acf2d75d37feb9a 67 SUPERFAMILY SSF116820 1 60 1.44E-23 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06775 c36896ab2200d31d0acf2d75d37feb9a 67 Pfam PF00833 Ribosomal S17 1 64 3.9E-15 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_04575 a2fa5592e4711470220786bb7d291baf 138 Pfam PF01850 PIN domain 3 132 6.2E-24 T 23-10-2018 IPR002716 PIN domain A3L01_04575 a2fa5592e4711470220786bb7d291baf 138 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 138 9.938 T 23-10-2018 IPR022907 VapC family GO:0004540 A3L01_04575 a2fa5592e4711470220786bb7d291baf 138 Gene3D G3DSA:3.40.50.1010 2 137 2.5E-19 T 23-10-2018 A3L01_04575 a2fa5592e4711470220786bb7d291baf 138 SUPERFAMILY SSF88723 1 136 8.97E-22 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L01_04575 a2fa5592e4711470220786bb7d291baf 138 SMART SM00670 1 130 0.0011 T 23-10-2018 IPR002716 PIN domain A3L01_08845 82cc6d8835c9128a2aa67623d75ac3e2 330 Gene3D G3DSA:3.50.50.60 18 315 5.9E-116 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_08845 82cc6d8835c9128a2aa67623d75ac3e2 330 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 154 174 - T 23-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 A3L01_08845 82cc6d8835c9128a2aa67623d75ac3e2 330 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 18 321 8.3E-124 T 23-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 A3L01_08845 82cc6d8835c9128a2aa67623d75ac3e2 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 19 41 1.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L01_08845 82cc6d8835c9128a2aa67623d75ac3e2 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 285 303 1.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L01_08845 82cc6d8835c9128a2aa67623d75ac3e2 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 72 82 1.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L01_08845 82cc6d8835c9128a2aa67623d75ac3e2 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 125 133 1.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L01_08845 82cc6d8835c9128a2aa67623d75ac3e2 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 213 229 1.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L01_08845 82cc6d8835c9128a2aa67623d75ac3e2 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 51 66 1.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L01_08845 82cc6d8835c9128a2aa67623d75ac3e2 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 147 159 1.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L01_08845 82cc6d8835c9128a2aa67623d75ac3e2 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 162 186 1.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L01_08845 82cc6d8835c9128a2aa67623d75ac3e2 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 251 272 1.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L01_08845 82cc6d8835c9128a2aa67623d75ac3e2 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 124 142 8.4E-41 T 23-10-2018 A3L01_08845 82cc6d8835c9128a2aa67623d75ac3e2 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 249 265 8.4E-41 T 23-10-2018 A3L01_08845 82cc6d8835c9128a2aa67623d75ac3e2 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 20 39 8.4E-41 T 23-10-2018 A3L01_08845 82cc6d8835c9128a2aa67623d75ac3e2 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 8.4E-41 T 23-10-2018 A3L01_08845 82cc6d8835c9128a2aa67623d75ac3e2 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 8.4E-41 T 23-10-2018 A3L01_08845 82cc6d8835c9128a2aa67623d75ac3e2 330 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 310 2.0E-61 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L01_08845 82cc6d8835c9128a2aa67623d75ac3e2 330 Gene3D G3DSA:3.50.50.60 136 257 5.9E-116 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_08845 82cc6d8835c9128a2aa67623d75ac3e2 330 SUPERFAMILY SSF51905 15 320 6.82E-62 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_04250 b83220d2f4462e9836117d4a89e48f42 416 SMART SM00471 48 188 3.2E-11 T 23-10-2018 IPR003607 HD/PDEase domain A3L01_04250 b83220d2f4462e9836117d4a89e48f42 416 Gene3D G3DSA:1.10.3210.10 3 289 8.0E-85 T 23-10-2018 A3L01_04250 b83220d2f4462e9836117d4a89e48f42 416 SUPERFAMILY SSF109604 3 412 5.95E-92 T 23-10-2018 A3L01_04250 b83220d2f4462e9836117d4a89e48f42 416 Pfam PF01966 HD domain 52 161 1.3E-13 T 23-10-2018 IPR006674 HD domain A3L01_09675 64921f9e0846937fd40c62f44775e29f 516 Gene3D G3DSA:1.20.1740.10 200 514 1.8E-6 T 23-10-2018 A3L01_09675 64921f9e0846937fd40c62f44775e29f 516 Pfam PF01235 Sodium:alanine symporter family 55 178 2.2E-35 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L01_09675 64921f9e0846937fd40c62f44775e29f 516 Pfam PF01235 Sodium:alanine symporter family 204 512 1.8E-99 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L01_09675 64921f9e0846937fd40c62f44775e29f 516 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 92 107 - T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L01_09675 64921f9e0846937fd40c62f44775e29f 516 TIGRFAM TIGR00835 agcS: amino acid carrier protein 206 511 8.7E-92 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L01_09675 64921f9e0846937fd40c62f44775e29f 516 PRINTS PR00175 Sodium/alanine symporter signature 480 500 2.9E-54 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L01_09675 64921f9e0846937fd40c62f44775e29f 516 PRINTS PR00175 Sodium/alanine symporter signature 408 430 2.9E-54 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L01_09675 64921f9e0846937fd40c62f44775e29f 516 PRINTS PR00175 Sodium/alanine symporter signature 363 381 2.9E-54 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L01_09675 64921f9e0846937fd40c62f44775e29f 516 PRINTS PR00175 Sodium/alanine symporter signature 272 291 2.9E-54 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L01_09675 64921f9e0846937fd40c62f44775e29f 516 PRINTS PR00175 Sodium/alanine symporter signature 92 114 2.9E-54 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L01_09675 64921f9e0846937fd40c62f44775e29f 516 PRINTS PR00175 Sodium/alanine symporter signature 244 262 2.9E-54 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L01_03265 4979b22a2919cade768ea8883f7b7089 449 Pfam PF01637 ATPase domain predominantly from Archaea 2 200 1.5E-23 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L01_03265 4979b22a2919cade768ea8883f7b7089 449 SUPERFAMILY SSF52540 2 240 1.02E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_03265 4979b22a2919cade768ea8883f7b7089 449 Gene3D G3DSA:3.40.50.300 1 167 7.0E-31 T 23-10-2018 A3L01_03265 4979b22a2919cade768ea8883f7b7089 449 Pfam PF03008 Archaea bacterial proteins of unknown function 305 398 4.3E-24 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L01_03265 4979b22a2919cade768ea8883f7b7089 449 SUPERFAMILY SSF52980 337 414 1.39E-6 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L01_03265 4979b22a2919cade768ea8883f7b7089 449 SUPERFAMILY SSF46785 239 313 4.12E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_07840 f5c2a1636503debc5ee7a33c24b4e69d 885 SMART SM00382 22 873 7.3E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_07840 f5c2a1636503debc5ee7a33c24b4e69d 885 Pfam PF04423 Rad50 zinc hook motif 420 467 5.0E-15 T 23-10-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A3L01_07840 f5c2a1636503debc5ee7a33c24b4e69d 885 Gene3D G3DSA:1.10.287.510 392 503 1.8E-26 T 23-10-2018 A3L01_07840 f5c2a1636503debc5ee7a33c24b4e69d 885 SUPERFAMILY SSF52540 1 870 2.36E-28 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_07840 f5c2a1636503debc5ee7a33c24b4e69d 885 SUPERFAMILY SSF75712 394 491 1.96E-18 T 23-10-2018 A3L01_07840 f5c2a1636503debc5ee7a33c24b4e69d 885 Pfam PF13476 AAA domain 5 203 8.6E-22 T 23-10-2018 IPR038729 Rad50/SbcC-type AAA domain A3L01_07840 f5c2a1636503debc5ee7a33c24b4e69d 885 Hamap MF_00449 DNA double-strand break repair Rad50 ATPase [rad50]. 1 880 13.484 T 23-10-2018 IPR022982 DNA double-strand break repair Rad50 ATPase, archaeal type A3L01_07840 f5c2a1636503debc5ee7a33c24b4e69d 885 Gene3D G3DSA:3.40.50.300 680 881 7.8E-43 T 23-10-2018 A3L01_07840 f5c2a1636503debc5ee7a33c24b4e69d 885 Gene3D G3DSA:3.40.50.300 1 214 8.0E-47 T 23-10-2018 A3L01_04190 2419e206fc07502d076f9d882143177b 366 TIGRFAM TIGR01370 TIGR01370: extracellular protein 59 359 2.0E-115 T 23-10-2018 IPR016063 Extracellular protein A3L01_04190 2419e206fc07502d076f9d882143177b 366 Gene3D G3DSA:3.20.20.70 74 366 1.4E-109 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_04190 2419e206fc07502d076f9d882143177b 366 SUPERFAMILY SSF51445 90 355 3.11E-47 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L01_04190 2419e206fc07502d076f9d882143177b 366 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 308 318 1.1E-65 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A3L01_04190 2419e206fc07502d076f9d882143177b 366 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 335 347 1.1E-65 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A3L01_04190 2419e206fc07502d076f9d882143177b 366 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 181 199 1.1E-65 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A3L01_04190 2419e206fc07502d076f9d882143177b 366 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 253 267 1.1E-65 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A3L01_04190 2419e206fc07502d076f9d882143177b 366 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 107 120 1.1E-65 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A3L01_04190 2419e206fc07502d076f9d882143177b 366 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 139 158 1.1E-65 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A3L01_04190 2419e206fc07502d076f9d882143177b 366 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 199 218 1.1E-65 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A3L01_04190 2419e206fc07502d076f9d882143177b 366 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 234 246 1.1E-65 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A3L01_04190 2419e206fc07502d076f9d882143177b 366 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 93 106 1.1E-65 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A3L01_04190 2419e206fc07502d076f9d882143177b 366 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 162 179 1.1E-65 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A3L01_04190 2419e206fc07502d076f9d882143177b 366 Pfam PF03537 Glycoside-hydrolase family GH114 92 347 1.4E-29 T 23-10-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain A3L01_04690 b00a483ce8bfb20158a7ddebaeb1ad62 93 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 2 93 9.7E-22 T 23-10-2018 IPR010038 MoaD, archaeal-type A3L01_04690 b00a483ce8bfb20158a7ddebaeb1ad62 93 SUPERFAMILY SSF54285 1 93 1.59E-18 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L01_04690 b00a483ce8bfb20158a7ddebaeb1ad62 93 Pfam PF02597 ThiS family 3 93 1.3E-16 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L01_04690 b00a483ce8bfb20158a7ddebaeb1ad62 93 Gene3D G3DSA:3.10.20.30 1 93 2.5E-25 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L01_08860 884a201df8af6323ec8e4900307c6bb9 97 PIRSF PIRSF004604 2 96 3.7E-30 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L01_08860 884a201df8af6323ec8e4900307c6bb9 97 ProDom PD029791 ORF 3'REGION GAP PF1875 PF0899 PH1831 B PHS036 7 79 3.0E-20 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L01_08860 884a201df8af6323ec8e4900307c6bb9 97 Pfam PF08967 Domain of unknown function (DUF1884) 5 81 9.7E-24 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L01_08860 884a201df8af6323ec8e4900307c6bb9 97 Gene3D G3DSA:3.30.2320.10 2 80 4.2E-23 T 23-10-2018 A3L01_08860 884a201df8af6323ec8e4900307c6bb9 97 SUPERFAMILY SSF111057 6 79 8.24E-24 T 23-10-2018 IPR036216 Hypothetical protein UCP004604 superfamily A3L01_09985 23877bbc842379830dae55989e6de6fd 405 Pfam PF04104 Eukaryotic and archaeal DNA primase, large subunit 143 369 8.4E-30 T 23-10-2018 IPR007238 DNA primase large subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 A3L01_09985 23877bbc842379830dae55989e6de6fd 405 Hamap MF_00701 DNA primase large subunit PriL [priL]. 1 389 28.635 T 23-10-2018 IPR023642 DNA primase large subunit PriL GO:0003896 A3L01_09985 23877bbc842379830dae55989e6de6fd 405 SUPERFAMILY SSF140914 2 249 9.55E-24 T 23-10-2018 A3L01_09985 23877bbc842379830dae55989e6de6fd 405 Gene3D G3DSA:1.20.930.50 8 224 1.8E-47 T 23-10-2018 A3L01_09985 23877bbc842379830dae55989e6de6fd 405 Gene3D G3DSA:2.20.20.80 109 171 1.8E-47 T 23-10-2018 A3L01_01000 f7727428c03ccb8fa7ad6e07555d5085 380 Pfam PF09414 RNA ligase 86 240 4.8E-18 T 23-10-2018 IPR021122 RNA ligase domain, REL/Rln2 A3L01_01000 f7727428c03ccb8fa7ad6e07555d5085 380 PRINTS PR01048 Hypothetical protein Y414 family signature 260 278 1.1E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L01_01000 f7727428c03ccb8fa7ad6e07555d5085 380 PRINTS PR01048 Hypothetical protein Y414 family signature 355 375 1.1E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L01_01000 f7727428c03ccb8fa7ad6e07555d5085 380 PRINTS PR01048 Hypothetical protein Y414 family signature 87 100 1.1E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L01_01000 f7727428c03ccb8fa7ad6e07555d5085 380 PRINTS PR01048 Hypothetical protein Y414 family signature 64 82 1.1E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L01_01000 f7727428c03ccb8fa7ad6e07555d5085 380 PRINTS PR01048 Hypothetical protein Y414 family signature 219 232 1.1E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L01_01000 f7727428c03ccb8fa7ad6e07555d5085 380 PRINTS PR01048 Hypothetical protein Y414 family signature 164 185 1.1E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L01_01000 f7727428c03ccb8fa7ad6e07555d5085 380 PRINTS PR01048 Hypothetical protein Y414 family signature 108 123 1.1E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L01_01000 f7727428c03ccb8fa7ad6e07555d5085 380 PRINTS PR01048 Hypothetical protein Y414 family signature 138 153 1.1E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L01_01000 f7727428c03ccb8fa7ad6e07555d5085 380 PRINTS PR01048 Hypothetical protein Y414 family signature 291 305 1.1E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L01_01000 f7727428c03ccb8fa7ad6e07555d5085 380 PRINTS PR01048 Hypothetical protein Y414 family signature 42 56 1.1E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L01_01000 f7727428c03ccb8fa7ad6e07555d5085 380 SUPERFAMILY SSF56091 63 263 1.5E-38 T 23-10-2018 A3L01_01000 f7727428c03ccb8fa7ad6e07555d5085 380 Gene3D G3DSA:3.30.70.3360 314 362 1.0E-37 T 23-10-2018 A3L01_01000 f7727428c03ccb8fa7ad6e07555d5085 380 Gene3D G3DSA:2.20.25.320 7 67 1.0E-22 T 23-10-2018 A3L01_01000 f7727428c03ccb8fa7ad6e07555d5085 380 TIGRFAM TIGR01209 TIGR01209: RNA ligase, Pab1020 family 11 380 2.5E-150 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L01_01000 f7727428c03ccb8fa7ad6e07555d5085 380 Gene3D G3DSA:3.30.70.3350 244 374 1.0E-37 T 23-10-2018 A3L01_01000 f7727428c03ccb8fa7ad6e07555d5085 380 Gene3D G3DSA:3.30.1490.70 70 241 1.3E-69 T 23-10-2018 A3L01_01000 f7727428c03ccb8fa7ad6e07555d5085 380 Gene3D G3DSA:3.30.470.30 96 197 1.3E-69 T 23-10-2018 A3L01_09225 91b9459bffc295bfc607ed5d244099e6 365 SUPERFAMILY SSF53335 179 359 2.67E-34 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_09225 91b9459bffc295bfc607ed5d244099e6 365 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 223 234 - T 23-10-2018 IPR000241 Putative RNA methylase domain A3L01_09225 91b9459bffc295bfc607ed5d244099e6 365 Pfam PF01170 Putative RNA methylase family UPF0020 191 358 8.6E-38 T 23-10-2018 IPR000241 Putative RNA methylase domain A3L01_09225 91b9459bffc295bfc607ed5d244099e6 365 SMART SM00981 86 182 5.6E-16 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L01_09225 91b9459bffc295bfc607ed5d244099e6 365 SUPERFAMILY SSF143437 77 182 7.5E-11 T 23-10-2018 A3L01_09225 91b9459bffc295bfc607ed5d244099e6 365 Gene3D G3DSA:3.30.2130.30 1 189 8.4E-83 T 23-10-2018 A3L01_09225 91b9459bffc295bfc607ed5d244099e6 365 Gene3D G3DSA:3.40.50.150 190 365 6.4E-51 T 23-10-2018 A3L01_09225 91b9459bffc295bfc607ed5d244099e6 365 Pfam PF02926 THUMP domain 30 182 6.8E-28 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L01_07765 713f02780bf04181569ca17ba3977fb5 227 Hamap MF_00350 DNA repair and recombination protein RadB [radB]. 8 217 36.939 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 A3L01_07765 713f02780bf04181569ca17ba3977fb5 227 PIRSF PIRSF003336 1 220 1.3E-98 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 A3L01_07765 713f02780bf04181569ca17ba3977fb5 227 Gene3D G3DSA:3.40.50.300 7 220 2.9E-57 T 23-10-2018 A3L01_07765 713f02780bf04181569ca17ba3977fb5 227 TIGRFAM TIGR02237 recomb_radB: DNA repair and recombination protein RadB 9 217 2.9E-71 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 A3L01_07765 713f02780bf04181569ca17ba3977fb5 227 Pfam PF08423 Rad51 2 217 3.6E-29 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 A3L01_07765 713f02780bf04181569ca17ba3977fb5 227 PRINTS PR01874 DNA repair protein radA signature 190 216 8.3E-8 T 23-10-2018 A3L01_07765 713f02780bf04181569ca17ba3977fb5 227 PRINTS PR01874 DNA repair protein radA signature 11 39 8.3E-8 T 23-10-2018 A3L01_07765 713f02780bf04181569ca17ba3977fb5 227 SMART SM00382 19 178 0.0014 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_07765 713f02780bf04181569ca17ba3977fb5 227 SUPERFAMILY SSF52540 2 219 1.03E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_04380 d8bb0669629e730bc1c93be18a7725ff 222 SUPERFAMILY SSF53448 6 221 3.07E-54 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_04380 d8bb0669629e730bc1c93be18a7725ff 222 Pfam PF00535 Glycosyl transferase family 2 8 167 1.4E-39 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L01_04380 d8bb0669629e730bc1c93be18a7725ff 222 Gene3D G3DSA:3.90.550.10 2 222 2.3E-63 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_09015 308a27c751efbca8ae07917223cc38bb 199 Gene3D G3DSA:3.40.50.620 6 154 1.9E-40 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_09015 308a27c751efbca8ae07917223cc38bb 199 SUPERFAMILY SSF52374 4 147 9.01E-20 T 23-10-2018 A3L01_09015 308a27c751efbca8ae07917223cc38bb 199 Pfam PF01467 Cytidylyltransferase-like 10 145 2.0E-13 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L01_09015 308a27c751efbca8ae07917223cc38bb 199 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 8 62 7.8E-13 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L01_03735 39a80d1415c5dc539ccc7a5059bd8f87 476 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 314 1.1E-137 T 23-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 A3L01_03735 39a80d1415c5dc539ccc7a5059bd8f87 476 SMART SM00840 356 417 9.2E-14 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A3L01_03735 39a80d1415c5dc539ccc7a5059bd8f87 476 Pfam PF09190 DALR domain 356 415 3.4E-16 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A3L01_03735 39a80d1415c5dc539ccc7a5059bd8f87 476 SUPERFAMILY SSF47323 316 473 1.66E-35 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_03735 39a80d1415c5dc539ccc7a5059bd8f87 476 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 474 39.932 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A3L01_03735 39a80d1415c5dc539ccc7a5059bd8f87 476 SUPERFAMILY SSF52374 4 314 3.84E-111 T 23-10-2018 A3L01_03735 39a80d1415c5dc539ccc7a5059bd8f87 476 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 473 4.9E-179 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A3L01_03735 39a80d1415c5dc539ccc7a5059bd8f87 476 Gene3D G3DSA:1.20.120.640 306 473 2.5E-38 T 23-10-2018 A3L01_03735 39a80d1415c5dc539ccc7a5059bd8f87 476 Gene3D G3DSA:3.40.50.620 1 305 1.4E-149 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_03735 39a80d1415c5dc539ccc7a5059bd8f87 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 3.8E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A3L01_03735 39a80d1415c5dc539ccc7a5059bd8f87 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 3.8E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A3L01_03735 39a80d1415c5dc539ccc7a5059bd8f87 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 3.8E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A3L01_03735 39a80d1415c5dc539ccc7a5059bd8f87 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 3.8E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A3L01_02630 db54cc0abf8f8bcecb38035e36330dda 272 SUPERFAMILY SSF51717 7 269 4.45E-81 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L01_02630 db54cc0abf8f8bcecb38035e36330dda 272 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 13 265 1.7E-72 T 23-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 A3L01_02630 db54cc0abf8f8bcecb38035e36330dda 272 Gene3D G3DSA:3.20.20.20 2 271 1.2E-90 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L01_02630 db54cc0abf8f8bcecb38035e36330dda 272 Pfam PF00809 Pterin binding enzyme 14 252 1.2E-61 T 23-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L01_08125 fec5ddc5d8753127a2b00a38c8b9b87b 299 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 172 295 1.5E-32 T 23-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain A3L01_08125 fec5ddc5d8753127a2b00a38c8b9b87b 299 Gene3D G3DSA:1.10.1040.10 172 296 6.7E-43 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A3L01_08125 fec5ddc5d8753127a2b00a38c8b9b87b 299 Gene3D G3DSA:3.40.50.720 1 171 5.1E-65 T 23-10-2018 A3L01_08125 fec5ddc5d8753127a2b00a38c8b9b87b 299 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 146 1.2E-36 T 23-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain A3L01_08125 fec5ddc5d8753127a2b00a38c8b9b87b 299 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 297 1.3E-82 T 23-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 A3L01_08125 fec5ddc5d8753127a2b00a38c8b9b87b 299 SUPERFAMILY SSF48179 172 295 5.78E-29 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A3L01_08125 fec5ddc5d8753127a2b00a38c8b9b87b 299 SUPERFAMILY SSF51735 1 149 3.19E-21 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 SMART SM00436 796 883 2.5E-42 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 SMART SM00487 81 331 3.2E-22 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1039 1055 6.0E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 769 782 6.0E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1133 1147 6.0E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 958 967 6.0E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 855 873 6.0E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 SUPERFAMILY SSF52540 326 625 9.75E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 Gene3D G3DSA:1.10.290.10 926 1050 3.9E-143 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 Gene3D G3DSA:3.40.50.300 546 629 1.4E-14 T 23-10-2018 A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 Gene3D G3DSA:3.40.50.300 320 498 2.4E-33 T 23-10-2018 A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 Gene3D G3DSA:2.20.20.30 680 723 7.7E-7 T 23-10-2018 A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 SMART SM00437 916 1172 7.9E-97 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 Pfam PF00270 DEAD/DEAH box helicase 88 222 4.3E-11 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 Pfam PF01131 DNA topoisomerase 820 1209 1.6E-82 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 Hamap MF_01125 Reverse gyrase [rgy]. 1 1220 65.213 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 SUPERFAMILY SSF52540 2 242 1.09E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 Gene3D G3DSA:1.10.460.10 825 1213 3.9E-143 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 SUPERFAMILY SSF56712 637 1218 7.85E-143 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 Gene3D G3DSA:2.60.510.20 877 1117 3.9E-143 T 23-10-2018 A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 TIGRFAM TIGR01054 rgy: reverse gyrase 2 1217 0.0 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 SMART SM00493 642 795 9.4E-45 T 23-10-2018 IPR006171 TOPRIM domain A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 Pfam PF01751 Toprim domain 644 805 2.9E-28 T 23-10-2018 IPR006171 TOPRIM domain A3L01_02345 12cbf63f5bade241550e263e38ba2a08 1221 Gene3D G3DSA:3.40.50.140 727 821 5.6E-21 T 23-10-2018 A3L01_05835 23cd12c058024a5c5feabbe06b351975 196 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 2 189 8.4E-58 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 A3L01_05835 23cd12c058024a5c5feabbe06b351975 196 Gene3D G3DSA:3.40.50.620 1 195 6.8E-57 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_05835 23cd12c058024a5c5feabbe06b351975 196 SUPERFAMILY SSF52402 1 193 2.21E-39 T 23-10-2018 A3L01_00095 6ea1b37ec38fa1a85d6694855722ca2d 429 SUPERFAMILY SSF51246 340 410 1.27E-16 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A3L01_00095 6ea1b37ec38fa1a85d6694855722ca2d 429 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 18 410 4.0E-187 T 23-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 A3L01_00095 6ea1b37ec38fa1a85d6694855722ca2d 429 Gene3D G3DSA:3.40.50.20 1 128 6.3E-56 T 23-10-2018 A3L01_00095 6ea1b37ec38fa1a85d6694855722ca2d 429 SUPERFAMILY SSF56059 118 324 4.55E-52 T 23-10-2018 A3L01_00095 6ea1b37ec38fa1a85d6694855722ca2d 429 Gene3D G3DSA:3.30.1490.20 129 200 3.8E-32 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L01_00095 6ea1b37ec38fa1a85d6694855722ca2d 429 Hamap MF_01643 Formate-dependent phosphoribosylglycinamide formyltransferase [purT]. 12 411 48.72 T 23-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 A3L01_00095 6ea1b37ec38fa1a85d6694855722ca2d 429 SUPERFAMILY SSF52440 8 115 9.64E-34 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L01_00095 6ea1b37ec38fa1a85d6694855722ca2d 429 Gene3D G3DSA:3.30.470.20 201 429 4.5E-79 T 23-10-2018 A3L01_00095 6ea1b37ec38fa1a85d6694855722ca2d 429 Pfam PF02222 ATP-grasp domain 127 303 7.9E-56 T 23-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type A3L01_05480 874541690520d133f91ae4f6f6b484f6 540 SUPERFAMILY SSF48239 405 536 3.84E-14 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L01_05480 874541690520d133f91ae4f6f6b484f6 540 SUPERFAMILY SSF48239 57 322 3.49E-13 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L01_05480 874541690520d133f91ae4f6f6b484f6 540 SUPERFAMILY SSF48239 5 140 6.98E-5 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L01_05480 874541690520d133f91ae4f6f6b484f6 540 Gene3D G3DSA:1.50.10.20 386 539 4.9E-9 T 23-10-2018 A3L01_05480 874541690520d133f91ae4f6f6b484f6 540 Gene3D G3DSA:1.50.10.20 160 327 3.9E-9 T 23-10-2018 A3L01_04460 a42b0faff1be048dfdfef288bba8f455 263 Pfam PF13230 Glutamine amidotransferases class-II 30 123 1.9E-7 T 23-10-2018 IPR026869 Putative glutamine amidotransferase type 2 A3L01_04460 a42b0faff1be048dfdfef288bba8f455 263 Gene3D G3DSA:3.60.20.10 32 261 8.7E-13 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L01_04460 a42b0faff1be048dfdfef288bba8f455 263 SUPERFAMILY SSF56235 36 245 6.51E-15 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L01_08660 fdeaadb718bbcbbd9d387c34d10c8f84 425 Pfam PF04055 Radical SAM superfamily 142 313 5.5E-25 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L01_08660 fdeaadb718bbcbbd9d387c34d10c8f84 425 TIGRFAM TIGR01578 MiaB-like-B: MiaB-like tRNA modifying enzyme, archaeal-type 3 423 6.8E-144 T 23-10-2018 IPR006466 MiaB-like tRNA modifying enzyme, archaeal-type Reactome: R-HSA-6782315 A3L01_08660 fdeaadb718bbcbbd9d387c34d10c8f84 425 Gene3D G3DSA:3.80.30.20 138 369 3.8E-74 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L01_08660 fdeaadb718bbcbbd9d387c34d10c8f84 425 SUPERFAMILY SSF102114 128 363 5.62E-54 T 23-10-2018 A3L01_08660 fdeaadb718bbcbbd9d387c34d10c8f84 425 Pfam PF00919 Uncharacterized protein family UPF0004 3 87 6.0E-23 T 23-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 A3L01_08660 fdeaadb718bbcbbd9d387c34d10c8f84 425 Pfam PF01938 TRAM domain 367 424 1.4E-7 T 23-10-2018 IPR002792 TRAM domain A3L01_08660 fdeaadb718bbcbbd9d387c34d10c8f84 425 Gene3D G3DSA:3.40.50.12160 2 125 7.2E-26 T 23-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily A3L01_08660 fdeaadb718bbcbbd9d387c34d10c8f84 425 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 142 162 - T 23-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 A3L01_08660 fdeaadb718bbcbbd9d387c34d10c8f84 425 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 421 1.6E-130 T 23-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 A3L01_08660 fdeaadb718bbcbbd9d387c34d10c8f84 425 SMART SM00729 138 355 2.2E-62 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L01_07710 464707121cd26d3a99586535817d822a 188 Gene3D G3DSA:3.30.930.10 1 188 2.3E-71 T 23-10-2018 A3L01_07710 464707121cd26d3a99586535817d822a 188 PIRSF PIRSF006503 1 188 2.5E-83 T 23-10-2018 IPR007162 Protein of unknown function DUF366 A3L01_07710 464707121cd26d3a99586535817d822a 188 Pfam PF04017 Domain of unknown function (DUF366) 5 185 3.2E-68 T 23-10-2018 IPR007162 Protein of unknown function DUF366 A3L01_07710 464707121cd26d3a99586535817d822a 188 ProDom PD022700 PH0223 5/5 GENOME PF0133 SEGMENT UNCHARACTERIZED MA4198 MJ0805 4 186 3.0E-92 T 23-10-2018 IPR007162 Protein of unknown function DUF366 A3L01_07710 464707121cd26d3a99586535817d822a 188 SUPERFAMILY SSF55681 3 186 2.19E-71 T 23-10-2018 A3L01_08365 14b0f43478791fcdc24f4a9fa79e3ed4 315 PIRSF PIRSF000723 1 314 1.3E-139 T 23-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 A3L01_08365 14b0f43478791fcdc24f4a9fa79e3ed4 315 SUPERFAMILY SSF53633 1 312 4.58E-86 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L01_08365 14b0f43478791fcdc24f4a9fa79e3ed4 315 TIGRFAM TIGR00746 arcC: carbamate kinase 2 314 2.7E-143 T 23-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 A3L01_08365 14b0f43478791fcdc24f4a9fa79e3ed4 315 Gene3D G3DSA:3.40.1160.10 1 315 1.2E-136 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L01_08365 14b0f43478791fcdc24f4a9fa79e3ed4 315 PRINTS PR01469 Bacterial carbamate kinase signature 214 229 5.2E-67 T 23-10-2018 A3L01_08365 14b0f43478791fcdc24f4a9fa79e3ed4 315 PRINTS PR01469 Bacterial carbamate kinase signature 44 63 5.2E-67 T 23-10-2018 A3L01_08365 14b0f43478791fcdc24f4a9fa79e3ed4 315 PRINTS PR01469 Bacterial carbamate kinase signature 77 95 5.2E-67 T 23-10-2018 A3L01_08365 14b0f43478791fcdc24f4a9fa79e3ed4 315 PRINTS PR01469 Bacterial carbamate kinase signature 161 180 5.2E-67 T 23-10-2018 A3L01_08365 14b0f43478791fcdc24f4a9fa79e3ed4 315 PRINTS PR01469 Bacterial carbamate kinase signature 184 202 5.2E-67 T 23-10-2018 A3L01_08365 14b0f43478791fcdc24f4a9fa79e3ed4 315 PRINTS PR01469 Bacterial carbamate kinase signature 269 284 5.2E-67 T 23-10-2018 A3L01_08365 14b0f43478791fcdc24f4a9fa79e3ed4 315 PRINTS PR01469 Bacterial carbamate kinase signature 112 131 5.2E-67 T 23-10-2018 A3L01_08365 14b0f43478791fcdc24f4a9fa79e3ed4 315 Pfam PF00696 Amino acid kinase family 2 295 1.7E-29 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A3L01_03700 161ea2e346368d9b20a82b3eecf47a69 512 Pfam PF00005 ABC transporter 23 173 4.4E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_03700 161ea2e346368d9b20a82b3eecf47a69 512 SUPERFAMILY SSF52540 241 495 1.07E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_03700 161ea2e346368d9b20a82b3eecf47a69 512 Pfam PF00005 ABC transporter 279 434 3.4E-17 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_03700 161ea2e346368d9b20a82b3eecf47a69 512 Gene3D G3DSA:3.40.50.300 1 242 6.4E-57 T 23-10-2018 A3L01_03700 161ea2e346368d9b20a82b3eecf47a69 512 Gene3D G3DSA:3.40.50.300 257 502 1.7E-43 T 23-10-2018 A3L01_03700 161ea2e346368d9b20a82b3eecf47a69 512 SMART SM00382 32 221 2.9E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_03700 161ea2e346368d9b20a82b3eecf47a69 512 SUPERFAMILY SSF52540 5 232 6.74E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_03700 161ea2e346368d9b20a82b3eecf47a69 512 ProSitePatterns PS00211 ABC transporters family signature. 407 421 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_08205 c37c4f5b55c748a9c7fadcfbdd390670 394 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 240 1.0E-80 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L01_08205 c37c4f5b55c748a9c7fadcfbdd390670 394 Gene3D G3DSA:3.40.50.920 253 391 5.5E-39 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L01_08205 c37c4f5b55c748a9c7fadcfbdd390670 394 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 262 365 7.6E-28 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A3L01_08205 c37c4f5b55c748a9c7fadcfbdd390670 394 Gene3D G3DSA:3.40.50.970 1 252 7.9E-105 T 23-10-2018 A3L01_08205 c37c4f5b55c748a9c7fadcfbdd390670 394 SUPERFAMILY SSF52922 254 369 4.19E-32 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L01_08205 c37c4f5b55c748a9c7fadcfbdd390670 394 SUPERFAMILY SSF52518 4 251 2.49E-69 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L01_00090 fdbec1b01c7308f4349c06ea5f4b365e 334 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 2 321 3.1E-121 T 23-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L01_00090 fdbec1b01c7308f4349c06ea5f4b365e 334 Pfam PF00586 AIR synthase related protein, N-terminal domain 57 159 5.2E-19 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L01_00090 fdbec1b01c7308f4349c06ea5f4b365e 334 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 2 330 37.35 T 23-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L01_00090 fdbec1b01c7308f4349c06ea5f4b365e 334 SUPERFAMILY SSF55326 2 165 9.87E-40 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L01_00090 fdbec1b01c7308f4349c06ea5f4b365e 334 Pfam PF02769 AIR synthase related protein, C-terminal domain 171 324 6.3E-24 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L01_00090 fdbec1b01c7308f4349c06ea5f4b365e 334 SUPERFAMILY SSF56042 167 326 5.98E-42 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L01_00090 fdbec1b01c7308f4349c06ea5f4b365e 334 Gene3D G3DSA:3.30.1330.10 2 165 5.5E-52 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L01_00090 fdbec1b01c7308f4349c06ea5f4b365e 334 Gene3D G3DSA:3.90.650.10 166 332 1.6E-48 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L01_00425 0262a1483287c24f9446a769b9473187 377 SUPERFAMILY SSF82689 256 358 1.44E-26 T 23-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A3L01_00425 0262a1483287c24f9446a769b9473187 377 SUPERFAMILY SSF82861 98 181 5.49E-8 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A3L01_00425 0262a1483287c24f9446a769b9473187 377 Pfam PF00924 Mechanosensitive ion channel 138 347 2.5E-52 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A3L01_00425 0262a1483287c24f9446a769b9473187 377 Gene3D G3DSA:3.30.70.100 254 351 1.2E-24 T 23-10-2018 A3L01_00425 0262a1483287c24f9446a769b9473187 377 SUPERFAMILY SSF50182 183 252 4.58E-15 T 23-10-2018 IPR010920 LSM domain superfamily A3L01_00425 0262a1483287c24f9446a769b9473187 377 Gene3D G3DSA:2.30.30.60 198 252 5.6E-11 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily A3L01_09505 dbf88d9a17b4b7542ef13978a82f6fe7 454 Gene3D G3DSA:3.40.50.300 3 165 2.0E-30 T 23-10-2018 A3L01_09505 dbf88d9a17b4b7542ef13978a82f6fe7 454 Pfam PF01637 ATPase domain predominantly from Archaea 5 199 1.8E-21 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L01_09505 dbf88d9a17b4b7542ef13978a82f6fe7 454 SUPERFAMILY SSF46785 217 352 1.4E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_09505 dbf88d9a17b4b7542ef13978a82f6fe7 454 Pfam PF03008 Archaea bacterial proteins of unknown function 307 397 3.7E-28 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L01_09505 dbf88d9a17b4b7542ef13978a82f6fe7 454 SUPERFAMILY SSF52540 3 239 2.23E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_09505 dbf88d9a17b4b7542ef13978a82f6fe7 454 Pfam PF01022 Bacterial regulatory protein, arsR family 240 281 1.6E-4 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_00595 c873eb96bbef0d21c17e0114eaecc2eb 204 Gene3D G3DSA:3.30.1490.150 117 190 1.1E-73 T 23-10-2018 A3L01_00595 c873eb96bbef0d21c17e0114eaecc2eb 204 Gene3D G3DSA:3.30.700.20 9 192 1.1E-73 T 23-10-2018 IPR027485 AMMECR1, N-terminal A3L01_00595 c873eb96bbef0d21c17e0114eaecc2eb 204 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 11 190 2.1E-59 T 23-10-2018 IPR027623 AmmeMemoRadiSam system protein A A3L01_00595 c873eb96bbef0d21c17e0114eaecc2eb 204 Hamap MF_00645 Protein . 5 188 41.944 T 23-10-2018 IPR023472 Uncharacterised protein family MJ0810 A3L01_00595 c873eb96bbef0d21c17e0114eaecc2eb 204 SUPERFAMILY SSF143447 4 202 6.93E-71 T 23-10-2018 IPR036071 AMMECR1 domain superfamily A3L01_00595 c873eb96bbef0d21c17e0114eaecc2eb 204 Pfam PF01871 AMMECR1 13 190 8.7E-55 T 23-10-2018 IPR002733 AMMECR1 domain A3L01_00595 c873eb96bbef0d21c17e0114eaecc2eb 204 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 4 197 3.8E-70 T 23-10-2018 IPR023473 AMMECR1 A3L01_00320 c5e450decfba0e777770e53729940072 562 Gene3D G3DSA:3.50.30.30 73 208 1.1E-53 T 23-10-2018 A3L01_00320 c5e450decfba0e777770e53729940072 562 SUPERFAMILY SSF52025 91 198 7.32E-7 T 23-10-2018 A3L01_00320 c5e450decfba0e777770e53729940072 562 Pfam PF02225 PA domain 118 188 2.1E-6 T 23-10-2018 IPR003137 PA domain A3L01_00320 c5e450decfba0e777770e53729940072 562 Pfam PF04389 Peptidase family M28 228 412 4.2E-18 T 23-10-2018 IPR007484 Peptidase M28 A3L01_00320 c5e450decfba0e777770e53729940072 562 Gene3D G3DSA:3.40.630.10 28 405 1.1E-53 T 23-10-2018 A3L01_00320 c5e450decfba0e777770e53729940072 562 SUPERFAMILY SSF53187 223 418 6.29E-30 T 23-10-2018 A3L01_05865 2a5f284a78a671331f1135be7febb89f 202 SUPERFAMILY SSF55469 3 201 3.14E-45 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L01_05865 2a5f284a78a671331f1135be7febb89f 202 Gene3D G3DSA:3.40.109.10 1 202 6.9E-50 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L01_05865 2a5f284a78a671331f1135be7febb89f 202 Pfam PF00881 Nitroreductase family 8 181 2.1E-36 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A3L01_03970 d270df660febbd001d425a222df7cb00 62 ProDom PD005132 RIBOSOMAL RRNA-BINDING METAL-BINDING RNA-BINDING ZINC RIBONUCLEOPROTEIN ZINC-FINGER L37 60S L37E 9 51 2.0E-16 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_03970 d270df660febbd001d425a222df7cb00 62 Pfam PF01907 Ribosomal protein L37e 3 56 3.0E-21 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_03970 d270df660febbd001d425a222df7cb00 62 SUPERFAMILY SSF57829 1 56 9.34E-19 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L01_03970 d270df660febbd001d425a222df7cb00 62 Gene3D G3DSA:2.20.25.30 1 57 6.2E-20 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_03970 d270df660febbd001d425a222df7cb00 62 ProSitePatterns PS01077 Ribosomal protein L37e signature. 4 24 - T 23-10-2018 IPR018267 Ribosomal protein L37e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_03970 d270df660febbd001d425a222df7cb00 62 Hamap MF_00547 50S ribosomal protein L37e [rpl37e]. 2 55 20.373 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01210 814d4b4748449f1ca5c6b3f9fdb56a26 139 Gene3D G3DSA:3.30.420.80 3 139 5.2E-65 T 23-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 A3L01_01210 814d4b4748449f1ca5c6b3f9fdb56a26 139 PIRSF PIRSF002131 1 138 2.2E-35 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A3L01_01210 814d4b4748449f1ca5c6b3f9fdb56a26 139 Pfam PF00411 Ribosomal protein S11 17 135 2.1E-47 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A3L01_01210 814d4b4748449f1ca5c6b3f9fdb56a26 139 TIGRFAM TIGR03628 arch_S11P: ribosomal protein uS11 15 131 7.0E-67 T 23-10-2018 IPR019961 Ribosomal protein S11, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01210 814d4b4748449f1ca5c6b3f9fdb56a26 139 ProSitePatterns PS00054 Ribosomal protein S11 signature. 104 126 - T 23-10-2018 IPR018102 Ribosomal S11, conserved site A3L01_01210 814d4b4748449f1ca5c6b3f9fdb56a26 139 SUPERFAMILY SSF53137 11 137 3.47E-39 T 23-10-2018 A3L01_01210 814d4b4748449f1ca5c6b3f9fdb56a26 139 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 11 136 23.642 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A3L01_05975 93c5b6c0e42308ed9f79b6b12f2fbc7a 231 SUPERFAMILY SSF50891 89 218 3.79E-51 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A3L01_05975 93c5b6c0e42308ed9f79b6b12f2fbc7a 231 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 4 202 1.1E-78 T 23-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A3L01_05975 93c5b6c0e42308ed9f79b6b12f2fbc7a 231 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 9 211 3.9E-75 T 23-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A3L01_05975 93c5b6c0e42308ed9f79b6b12f2fbc7a 231 SUPERFAMILY SSF160467 4 93 4.71E-22 T 23-10-2018 A3L01_05975 93c5b6c0e42308ed9f79b6b12f2fbc7a 231 SMART SM00796 3 202 3.9E-114 T 23-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A3L01_05975 93c5b6c0e42308ed9f79b6b12f2fbc7a 231 Gene3D G3DSA:2.40.100.10 87 227 1.1E-64 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A3L01_05975 93c5b6c0e42308ed9f79b6b12f2fbc7a 231 Gene3D G3DSA:3.30.1360.40 4 86 4.4E-25 T 23-10-2018 A3L01_03440 31485e2e42f23ddb56b906531df32cc0 313 Gene3D G3DSA:3.40.50.300 1 222 4.5E-60 T 23-10-2018 A3L01_03440 31485e2e42f23ddb56b906531df32cc0 313 SUPERFAMILY SSF52540 4 217 2.09E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_03440 31485e2e42f23ddb56b906531df32cc0 313 Pfam PF00005 ABC transporter 21 157 5.3E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_03440 31485e2e42f23ddb56b906531df32cc0 313 SMART SM00382 29 215 5.1E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_03290 eec74e6ae023c9805e40e89a96682f48 141 Gene3D G3DSA:1.10.10.10 79 140 1.2E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_08030 0f97f4910f95e387158994a2416b9383 715 Pfam PF00128 Alpha amylase, catalytic domain 62 382 3.5E-53 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L01_08030 0f97f4910f95e387158994a2416b9383 715 Gene3D G3DSA:2.60.40.10 504 581 5.7E-15 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_08030 0f97f4910f95e387158994a2416b9383 715 SUPERFAMILY SSF81296 505 577 2.64E-13 T 23-10-2018 IPR014756 Immunoglobulin E-set A3L01_08030 0f97f4910f95e387158994a2416b9383 715 SUPERFAMILY SSF51011 423 501 3.42E-14 T 23-10-2018 A3L01_08030 0f97f4910f95e387158994a2416b9383 715 SMART SM00642 31 414 1.7E-78 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L01_08030 0f97f4910f95e387158994a2416b9383 715 Gene3D G3DSA:2.60.40.1180 417 501 4.7E-11 T 23-10-2018 IPR013780 Glycosyl hydrolase, all-beta A3L01_08030 0f97f4910f95e387158994a2416b9383 715 Gene3D G3DSA:3.20.20.80 23 416 5.4E-105 T 23-10-2018 A3L01_08030 0f97f4910f95e387158994a2416b9383 715 SUPERFAMILY SSF51445 25 420 2.96E-80 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L01_08030 0f97f4910f95e387158994a2416b9383 715 Pfam PF16657 Maltogenic Amylase, C-terminal domain 423 496 4.8E-8 T 23-10-2018 IPR032091 Maltogenic Amylase, C-terminal A3L01_08030 0f97f4910f95e387158994a2416b9383 715 Pfam PF01833 IPT/TIG domain 506 584 9.0E-10 T 23-10-2018 IPR002909 IPT domain A3L01_00135 c75cfe36cada6d31481c0d5df1f601ca 307 SUPERFAMILY SSF52402 3 224 9.92E-54 T 23-10-2018 A3L01_00135 c75cfe36cada6d31481c0d5df1f601ca 307 Pfam PF02540 NAD synthase 5 82 4.8E-7 T 23-10-2018 IPR022310 NAD/GMP synthase A3L01_00135 c75cfe36cada6d31481c0d5df1f601ca 307 Gene3D G3DSA:3.40.50.620 2 189 3.5E-78 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_00135 c75cfe36cada6d31481c0d5df1f601ca 307 Gene3D G3DSA:3.30.300.10 190 307 1.5E-52 T 23-10-2018 A3L01_00135 c75cfe36cada6d31481c0d5df1f601ca 307 Pfam PF00958 GMP synthase C terminal domain 218 306 7.1E-34 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A3L01_00135 c75cfe36cada6d31481c0d5df1f601ca 307 SUPERFAMILY SSF54810 189 307 1.2E-44 T 23-10-2018 A3L01_00135 c75cfe36cada6d31481c0d5df1f601ca 307 Hamap MF_00345 GMP synthase [glutamine-hydrolyzing] subunit B [guaAB]. 1 307 45.414 T 23-10-2018 IPR026598 GMP synthase subunit B KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 A3L01_00135 c75cfe36cada6d31481c0d5df1f601ca 307 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 5 307 1.3E-150 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A3L01_00265 7ff2e20d4fe9cfb428b41a844b3d72b4 354 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 35 50 1.7E-6 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L01_00265 7ff2e20d4fe9cfb428b41a844b3d72b4 354 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 86 97 1.7E-6 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L01_00265 7ff2e20d4fe9cfb428b41a844b3d72b4 354 SUPERFAMILY SSF51306 35 102 1.06E-12 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A3L01_00265 7ff2e20d4fe9cfb428b41a844b3d72b4 354 Gene3D G3DSA:2.10.109.10 36 124 1.3E-7 T 23-10-2018 A3L01_00265 7ff2e20d4fe9cfb428b41a844b3d72b4 354 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 4 108 4.7E-20 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L01_00265 7ff2e20d4fe9cfb428b41a844b3d72b4 354 Pfam PF00717 Peptidase S24-like 36 94 3.8E-11 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A3L01_07250 3494390c88491361ee736184d07f8594 226 PRINTS PR00052 Fibrillarin signature 23 42 2.0E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L01_07250 3494390c88491361ee736184d07f8594 226 PRINTS PR00052 Fibrillarin signature 46 65 2.0E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L01_07250 3494390c88491361ee736184d07f8594 226 PRINTS PR00052 Fibrillarin signature 73 94 2.0E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L01_07250 3494390c88491361ee736184d07f8594 226 PRINTS PR00052 Fibrillarin signature 204 225 2.0E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L01_07250 3494390c88491361ee736184d07f8594 226 PRINTS PR00052 Fibrillarin signature 123 152 2.0E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L01_07250 3494390c88491361ee736184d07f8594 226 PRINTS PR00052 Fibrillarin signature 153 182 2.0E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L01_07250 3494390c88491361ee736184d07f8594 226 PRINTS PR00052 Fibrillarin signature 98 115 2.0E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L01_07250 3494390c88491361ee736184d07f8594 226 Pfam PF01269 Fibrillarin 4 224 2.9E-102 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L01_07250 3494390c88491361ee736184d07f8594 226 Gene3D G3DSA:3.30.200.20 1 50 4.2E-25 T 23-10-2018 A3L01_07250 3494390c88491361ee736184d07f8594 226 SUPERFAMILY SSF53335 3 225 1.24E-60 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_07250 3494390c88491361ee736184d07f8594 226 ProSitePatterns PS00566 Fibrillarin signature. 98 112 - T 23-10-2018 IPR020813 Fibrillarin, conserved site GO:0003723|GO:0006364|GO:0008168 A3L01_07250 3494390c88491361ee736184d07f8594 226 Gene3D G3DSA:3.40.50.150 51 226 1.8E-75 T 23-10-2018 A3L01_07250 3494390c88491361ee736184d07f8594 226 SMART SM01206 3 226 6.4E-148 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L01_07250 3494390c88491361ee736184d07f8594 226 PIRSF PIRSF006540 1 226 1.2E-101 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L01_07250 3494390c88491361ee736184d07f8594 226 Hamap MF_00351 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase [flpA]. 16 226 44.349 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L01_10050 236dcf339e1208a4cd326eed75ba074f 454 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 378 435 5.5E-12 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_10050 236dcf339e1208a4cd326eed75ba074f 454 Gene3D G3DSA:3.40.120.10 162 344 1.7E-48 T 23-10-2018 A3L01_10050 236dcf339e1208a4cd326eed75ba074f 454 SUPERFAMILY SSF53738 147 247 2.35E-27 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_10050 236dcf339e1208a4cd326eed75ba074f 454 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 129 3.3E-39 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_10050 236dcf339e1208a4cd326eed75ba074f 454 Gene3D G3DSA:3.30.310.50 360 452 3.3E-17 T 23-10-2018 A3L01_10050 236dcf339e1208a4cd326eed75ba074f 454 SUPERFAMILY SSF55957 355 447 1.83E-20 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_10050 236dcf339e1208a4cd326eed75ba074f 454 Gene3D G3DSA:3.40.120.10 1 145 1.3E-46 T 23-10-2018 A3L01_10050 236dcf339e1208a4cd326eed75ba074f 454 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 88 97 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_10050 236dcf339e1208a4cd326eed75ba074f 454 Gene3D G3DSA:3.40.120.10 246 349 1.7E-48 T 23-10-2018 A3L01_10050 236dcf339e1208a4cd326eed75ba074f 454 SUPERFAMILY SSF53738 2 169 5.1E-41 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_10050 236dcf339e1208a4cd326eed75ba074f 454 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 1 439 1.1E-147 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_10050 236dcf339e1208a4cd326eed75ba074f 454 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 149 245 2.1E-25 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_10050 236dcf339e1208a4cd326eed75ba074f 454 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 250 356 6.3E-7 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_10050 236dcf339e1208a4cd326eed75ba074f 454 SUPERFAMILY SSF53738 250 351 3.83E-12 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_10050 236dcf339e1208a4cd326eed75ba074f 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 87 101 1.6E-16 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_10050 236dcf339e1208a4cd326eed75ba074f 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 163 182 1.6E-16 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_10050 236dcf339e1208a4cd326eed75ba074f 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 197 210 1.6E-16 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_10050 236dcf339e1208a4cd326eed75ba074f 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 225 240 1.6E-16 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_03770 389acf8ef7f601583d67e0e41176980e 866 PIRSF PIRSF037307 7 866 5.8E-287 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 A3L01_03770 389acf8ef7f601583d67e0e41176980e 866 SMART SM00490 302 388 4.8E-17 T 23-10-2018 IPR001650 Helicase, C-terminal A3L01_03770 389acf8ef7f601583d67e0e41176980e 866 SUPERFAMILY SSF52540 49 392 4.12E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_03770 389acf8ef7f601583d67e0e41176980e 866 SMART SM00382 50 428 9.9E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_03770 389acf8ef7f601583d67e0e41176980e 866 Pfam PF08494 DEAD/H associated 642 830 2.1E-53 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 A3L01_03770 389acf8ef7f601583d67e0e41176980e 866 Pfam PF00271 Helicase conserved C-terminal domain 279 384 1.7E-15 T 23-10-2018 IPR001650 Helicase, C-terminal A3L01_03770 389acf8ef7f601583d67e0e41176980e 866 Pfam PF00270 DEAD/DEAH box helicase 38 222 3.3E-26 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L01_03770 389acf8ef7f601583d67e0e41176980e 866 Gene3D G3DSA:3.40.50.300 264 420 2.9E-24 T 23-10-2018 A3L01_03770 389acf8ef7f601583d67e0e41176980e 866 SMART SM00487 33 261 2.0E-33 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L01_03770 389acf8ef7f601583d67e0e41176980e 866 Gene3D G3DSA:3.40.50.300 15 238 3.1E-53 T 23-10-2018 A3L01_04865 35c6e549f0b21be81206b25b00d45a59 429 Pfam PF00464 Serine hydroxymethyltransferase 10 390 4.9E-80 T 23-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A3L01_04865 35c6e549f0b21be81206b25b00d45a59 429 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 5 418 43.012 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A3L01_04865 35c6e549f0b21be81206b25b00d45a59 429 Gene3D G3DSA:3.90.1150.10 281 426 3.5E-52 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L01_04865 35c6e549f0b21be81206b25b00d45a59 429 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 220 236 - T 23-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A3L01_04865 35c6e549f0b21be81206b25b00d45a59 429 PIRSF PIRSF000412 3 426 1.9E-144 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A3L01_04865 35c6e549f0b21be81206b25b00d45a59 429 SUPERFAMILY SSF53383 5 428 5.11E-132 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L01_04865 35c6e549f0b21be81206b25b00d45a59 429 Gene3D G3DSA:3.40.640.10 38 280 4.9E-83 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L01_04615 c4e25c09c77c05c84729be5f37325004 562 ProDom PD013790 TOPOISOMERASE ISOMERASE SUBUNIT DNA B VI TYPE II NUCLEOTIDE-BINDING ATP-BINDING 353 550 3.0E-102 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 A3L01_04615 c4e25c09c77c05c84729be5f37325004 562 Gene3D G3DSA:1.10.8.50 233 310 4.9E-9 T 23-10-2018 A3L01_04615 c4e25c09c77c05c84729be5f37325004 562 PIRSF PIRSF006553 1 562 4.6E-213 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A3L01_04615 c4e25c09c77c05c84729be5f37325004 562 SMART SM00387 31 182 9.2E-10 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A3L01_04615 c4e25c09c77c05c84729be5f37325004 562 Gene3D G3DSA:3.30.565.10 1 232 7.7E-68 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A3L01_04615 c4e25c09c77c05c84729be5f37325004 562 SUPERFAMILY SSF54211 353 514 7.59E-61 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L01_04615 c4e25c09c77c05c84729be5f37325004 562 TIGRFAM TIGR01052 top6b: DNA topoisomerase VI, B subunit 10 532 1.3E-231 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A3L01_04615 c4e25c09c77c05c84729be5f37325004 562 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 146 3.1E-12 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A3L01_04615 c4e25c09c77c05c84729be5f37325004 562 Gene3D G3DSA:3.30.230.10 353 562 3.2E-72 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L01_04615 c4e25c09c77c05c84729be5f37325004 562 SUPERFAMILY SSF55874 18 229 3.27E-27 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A3L01_04615 c4e25c09c77c05c84729be5f37325004 562 Pfam PF09239 Topoisomerase VI B subunit, transducer 354 507 4.8E-57 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 A3L01_04615 c4e25c09c77c05c84729be5f37325004 562 Hamap MF_00322 Type 2 DNA topoisomerase 6 subunit B [top6B]. 8 550 31.539 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A3L01_05515 acedad0b4562c4caf6a8f3700872d5fb 572 Pfam PF00482 Type II secretion system (T2SS), protein F 88 215 3.4E-7 T 23-10-2018 IPR018076 Type II secretion system F domain A3L01_05515 acedad0b4562c4caf6a8f3700872d5fb 572 Pfam PF00482 Type II secretion system (T2SS), protein F 337 462 5.3E-8 T 23-10-2018 IPR018076 Type II secretion system F domain A3L01_09385 0bca771150382df9321ca9953a4a26e8 427 SMART SM00984 317 415 3.3E-39 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L01_09385 0bca771150382df9321ca9953a4a26e8 427 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 188 3.4E-64 T 23-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L01_09385 0bca771150382df9321ca9953a4a26e8 427 PIRSF PIRSF000124 1 427 1.3E-138 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L01_09385 0bca771150382df9321ca9953a4a26e8 427 SUPERFAMILY SSF51735 1 193 9.18E-54 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_09385 0bca771150382df9321ca9953a4a26e8 427 SUPERFAMILY SSF52413 303 417 4.45E-31 T 23-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 A3L01_09385 0bca771150382df9321ca9953a4a26e8 427 Gene3D G3DSA:3.40.50.720 217 427 1.7E-77 T 23-10-2018 A3L01_09385 0bca771150382df9321ca9953a4a26e8 427 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 318 412 7.1E-26 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L01_09385 0bca771150382df9321ca9953a4a26e8 427 Gene3D G3DSA:3.40.50.720 1 216 1.3E-75 T 23-10-2018 A3L01_09385 0bca771150382df9321ca9953a4a26e8 427 PIRSF PIRSF500134 1 423 1.6E-144 T 23-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 A3L01_09385 0bca771150382df9321ca9953a4a26e8 427 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 410 1.1E-140 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L01_09385 0bca771150382df9321ca9953a4a26e8 427 SUPERFAMILY SSF48179 202 296 1.39E-32 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A3L01_09385 0bca771150382df9321ca9953a4a26e8 427 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 202 294 1.7E-38 T 23-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L01_02660 eaf1d2ac90cd39538b4cda73ec2b2235 464 SMART SM00490 328 406 9.2E-13 T 23-10-2018 IPR001650 Helicase, C-terminal A3L01_02660 eaf1d2ac90cd39538b4cda73ec2b2235 464 SMART SM00487 91 262 6.4E-26 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L01_02660 eaf1d2ac90cd39538b4cda73ec2b2235 464 Gene3D G3DSA:3.40.50.300 274 453 4.0E-33 T 23-10-2018 A3L01_02660 eaf1d2ac90cd39538b4cda73ec2b2235 464 Gene3D G3DSA:3.40.50.300 85 261 1.6E-33 T 23-10-2018 A3L01_02660 eaf1d2ac90cd39538b4cda73ec2b2235 464 Pfam PF04851 Type III restriction enzyme, res subunit 94 231 2.0E-17 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A3L01_02660 eaf1d2ac90cd39538b4cda73ec2b2235 464 SUPERFAMILY SSF52540 27 210 1.02E-15 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_02660 eaf1d2ac90cd39538b4cda73ec2b2235 464 SUPERFAMILY SSF52540 136 419 2.02E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_02660 eaf1d2ac90cd39538b4cda73ec2b2235 464 Pfam PF00271 Helicase conserved C-terminal domain 306 404 1.8E-11 T 23-10-2018 IPR001650 Helicase, C-terminal A3L01_08015 5a8991b9ae3c656e187d8ca89dd091b2 417 Pfam PF01882 Protein of unknown function DUF58 187 271 2.8E-25 T 23-10-2018 IPR002881 Domain of unknown function DUF58 A3L01_03260 94403098e0e108901899cfbca5b72792 293 PIRSF PIRSF001365 1 291 3.3E-80 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L01_03260 94403098e0e108901899cfbca5b72792 293 SUPERFAMILY SSF51569 2 290 4.08E-79 T 23-10-2018 A3L01_03260 94403098e0e108901899cfbca5b72792 293 Gene3D G3DSA:3.20.20.70 1 291 3.7E-89 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_03260 94403098e0e108901899cfbca5b72792 293 SMART SM01130 1 292 5.3E-95 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L01_03260 94403098e0e108901899cfbca5b72792 293 Pfam PF00701 Dihydrodipicolinate synthetase family 2 289 7.0E-60 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L01_03260 94403098e0e108901899cfbca5b72792 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 126 143 5.8E-17 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L01_03260 94403098e0e108901899cfbca5b72792 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 5.8E-17 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L01_03260 94403098e0e108901899cfbca5b72792 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 101 117 5.8E-17 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L01_03260 94403098e0e108901899cfbca5b72792 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 69 87 5.8E-17 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L01_03260 94403098e0e108901899cfbca5b72792 293 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 131 161 - T 23-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 A3L01_08110 4fcbd94298aaad97b6e396991315d49b 430 SUPERFAMILY SSF52540 30 228 1.22E-18 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_08110 4fcbd94298aaad97b6e396991315d49b 430 Pfam PF13635 Domain of unknown function (DUF4143) 213 362 1.6E-14 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 A3L01_08110 4fcbd94298aaad97b6e396991315d49b 430 Pfam PF13173 AAA domain 43 160 1.6E-27 T 23-10-2018 A3L01_02940 a91fa22fc4ae598861398de91195f079 618 Gene3D G3DSA:3.60.9.10 1 205 3.7E-72 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L01_02940 a91fa22fc4ae598861398de91195f079 618 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 7 200 1.1E-68 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L01_02940 a91fa22fc4ae598861398de91195f079 618 SMART SM00790 4 204 6.9E-114 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L01_02940 a91fa22fc4ae598861398de91195f079 618 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 219 597 3.6E-95 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L01_02940 a91fa22fc4ae598861398de91195f079 618 Gene3D G3DSA:1.10.599.10 235 597 2.0E-88 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A3L01_02940 a91fa22fc4ae598861398de91195f079 618 SUPERFAMILY SSF48310 207 600 2.09E-100 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L01_02940 a91fa22fc4ae598861398de91195f079 618 Gene3D G3DSA:1.10.569.10 237 428 2.0E-88 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L01_02940 a91fa22fc4ae598861398de91195f079 618 SUPERFAMILY SSF56228 1 203 8.5E-66 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L01_06605 0e917fa15665c1690a7d2f39443de280 185 SUPERFAMILY SSF52540 2 182 1.58E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06605 0e917fa15665c1690a7d2f39443de280 185 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 5.6E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_06605 0e917fa15665c1690a7d2f39443de280 185 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 65 80 5.6E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_06605 0e917fa15665c1690a7d2f39443de280 185 Pfam PF01926 50S ribosome-binding GTPase 3 136 4.4E-22 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_06605 0e917fa15665c1690a7d2f39443de280 185 Gene3D G3DSA:3.40.50.300 1 181 4.5E-37 T 23-10-2018 A3L01_06605 0e917fa15665c1690a7d2f39443de280 185 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 177 5.2E-22 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L01_08065 4dffa7e82926583ca1ccc7fed6579e2b 428 Pfam PF03600 Citrate transporter 18 368 1.3E-53 T 23-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 A3L01_08065 4dffa7e82926583ca1ccc7fed6579e2b 428 PRINTS PR00758 Arsenical pump membrane protein signature 364 389 7.2E-17 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L01_08065 4dffa7e82926583ca1ccc7fed6579e2b 428 PRINTS PR00758 Arsenical pump membrane protein signature 103 127 7.2E-17 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L01_08065 4dffa7e82926583ca1ccc7fed6579e2b 428 PRINTS PR00758 Arsenical pump membrane protein signature 397 421 7.2E-17 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L01_08065 4dffa7e82926583ca1ccc7fed6579e2b 428 PRINTS PR00758 Arsenical pump membrane protein signature 324 346 7.2E-17 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L01_08065 4dffa7e82926583ca1ccc7fed6579e2b 428 PRINTS PR00758 Arsenical pump membrane protein signature 223 248 7.2E-17 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L01_08065 4dffa7e82926583ca1ccc7fed6579e2b 428 PRINTS PR00758 Arsenical pump membrane protein signature 280 304 7.2E-17 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L01_02120 ab7803f19e633927b1afca0df9dbd5af 572 Gene3D G3DSA:2.40.240.100 409 571 4.1E-44 T 23-10-2018 A3L01_02120 ab7803f19e633927b1afca0df9dbd5af 572 SUPERFAMILY SSF52374 99 414 3.49E-91 T 23-10-2018 A3L01_02120 ab7803f19e633927b1afca0df9dbd5af 572 Gene3D G3DSA:3.40.50.620 93 408 2.7E-119 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_02120 ab7803f19e633927b1afca0df9dbd5af 572 TIGRFAM TIGR00463 gltX_arch: glutamate--tRNA ligase 3 572 2.6E-212 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L01_02120 ab7803f19e633927b1afca0df9dbd5af 572 Hamap MF_02076 Glutamate--tRNA ligase [gltX]. 7 570 39.69 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L01_02120 ab7803f19e633927b1afca0df9dbd5af 572 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 99 405 3.8E-83 T 23-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 A3L01_02120 ab7803f19e633927b1afca0df9dbd5af 572 PRINTS PR00987 Glutamyl-tRNA synthetase signature 103 115 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L01_02120 ab7803f19e633927b1afca0df9dbd5af 572 PRINTS PR00987 Glutamyl-tRNA synthetase signature 117 128 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L01_02120 ab7803f19e633927b1afca0df9dbd5af 572 PRINTS PR00987 Glutamyl-tRNA synthetase signature 132 145 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L01_02120 ab7803f19e633927b1afca0df9dbd5af 572 PRINTS PR00987 Glutamyl-tRNA synthetase signature 296 304 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L01_02120 ab7803f19e633927b1afca0df9dbd5af 572 PRINTS PR00987 Glutamyl-tRNA synthetase signature 280 290 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L01_02120 ab7803f19e633927b1afca0df9dbd5af 572 Gene3D G3DSA:2.40.240.10 418 517 4.1E-44 T 23-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L01_02120 ab7803f19e633927b1afca0df9dbd5af 572 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 409 559 1.6E-28 T 23-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L01_02120 ab7803f19e633927b1afca0df9dbd5af 572 SUPERFAMILY SSF50715 409 562 1.83E-29 T 23-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L01_03505 86b9cd8f370e057a9c43e859513f56ce 212 SUPERFAMILY SSF46785 3 80 1.99E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_03505 86b9cd8f370e057a9c43e859513f56ce 212 Pfam PF13545 Crp-like helix-turn-helix domain 8 58 2.7E-8 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L01_03505 86b9cd8f370e057a9c43e859513f56ce 212 Hamap MF_01285 Riboflavin kinase [ribK]. 86 209 24.787 T 23-10-2018 IPR023470 Riboflavin kinase, archaeal GO:0008531|GO:0009231 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 A3L01_03505 86b9cd8f370e057a9c43e859513f56ce 212 Gene3D G3DSA:2.40.30.30 85 212 6.7E-39 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 A3L01_03505 86b9cd8f370e057a9c43e859513f56ce 212 SMART SM00419 14 66 5.0E-5 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L01_03505 86b9cd8f370e057a9c43e859513f56ce 212 Pfam PF01982 Domain of unknown function DUF120 92 209 6.2E-36 T 23-10-2018 IPR023602 Riboflavin kinase domain, CTP-dependent GO:0016773 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 A3L01_03505 86b9cd8f370e057a9c43e859513f56ce 212 Gene3D G3DSA:1.10.10.10 1 83 2.4E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_03505 86b9cd8f370e057a9c43e859513f56ce 212 SUPERFAMILY SSF82114 87 209 8.83E-39 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 A3L01_06560 fe1594153ea5e7bd2762076f82a77626 189 Pfam PF04199 Putative cyclase 3 134 1.4E-24 T 23-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A3L01_06560 fe1594153ea5e7bd2762076f82a77626 189 SUPERFAMILY SSF102198 2 188 4.45E-54 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A3L01_06560 fe1594153ea5e7bd2762076f82a77626 189 Gene3D G3DSA:3.50.30.50 1 188 3.3E-57 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A3L01_03000 d8cc7e5e3ddad04367d1606e1bf759b8 86 TIGRFAM TIGR00280 eL43_euk_arch: ribosomal protein eL43 1 80 8.7E-37 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_03000 d8cc7e5e3ddad04367d1606e1bf759b8 86 Gene3D G3DSA:2.20.25.30 9 86 1.4E-31 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_03000 d8cc7e5e3ddad04367d1606e1bf759b8 86 SUPERFAMILY SSF57829 10 80 1.22E-28 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L01_03000 d8cc7e5e3ddad04367d1606e1bf759b8 86 Pfam PF01780 Ribosomal L37ae protein family 3 82 1.2E-33 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_03000 d8cc7e5e3ddad04367d1606e1bf759b8 86 Hamap MF_00327 50S ribosomal protein L37Ae [rpl37ae]. 3 71 24.916 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_10065 3c8a491232f1c4eecb70c1c1982a4957 1345 Gene3D G3DSA:2.60.40.1190 1034 1269 2.2E-62 T 23-10-2018 A3L01_10065 3c8a491232f1c4eecb70c1c1982a4957 1345 Gene3D G3DSA:2.60.40.1190 789 1028 9.7E-66 T 23-10-2018 A3L01_10065 3c8a491232f1c4eecb70c1c1982a4957 1345 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 1325 1344 4.6E-6 T 23-10-2018 IPR027552 CGP-CTERM domain A3L01_10065 3c8a491232f1c4eecb70c1c1982a4957 1345 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 792 1024 6.9E-78 T 23-10-2018 IPR019248 Glucodextranase-like, C-terminal A3L01_10065 3c8a491232f1c4eecb70c1c1982a4957 1345 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 1036 1264 3.9E-73 T 23-10-2018 IPR019248 Glucodextranase-like, C-terminal A3L01_10065 3c8a491232f1c4eecb70c1c1982a4957 1345 SUPERFAMILY SSF49344 1035 1267 2.47E-77 T 23-10-2018 A3L01_10065 3c8a491232f1c4eecb70c1c1982a4957 1345 Pfam PF03065 Glycosyl hydrolase family 57 36 537 7.2E-128 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A3L01_10065 3c8a491232f1c4eecb70c1c1982a4957 1345 SUPERFAMILY SSF88713 32 576 4.77E-68 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L01_10065 3c8a491232f1c4eecb70c1c1982a4957 1345 Gene3D G3DSA:3.20.110.20 219 520 2.5E-25 T 23-10-2018 A3L01_10065 3c8a491232f1c4eecb70c1c1982a4957 1345 SUPERFAMILY SSF49344 791 1025 1.26E-79 T 23-10-2018 A3L01_10170 4fca4f7b4a4cdb80faa72b3a9042c828 269 PIRSF PIRSF000915 3 263 1.4E-64 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A3L01_10170 4fca4f7b4a4cdb80faa72b3a9042c828 269 Gene3D G3DSA:3.40.50.1000 5 251 1.0E-92 T 23-10-2018 IPR023214 HAD superfamily A3L01_10170 4fca4f7b4a4cdb80faa72b3a9042c828 269 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 4 233 5.0E-48 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A3L01_10170 4fca4f7b4a4cdb80faa72b3a9042c828 269 Pfam PF13242 HAD-hyrolase-like 184 257 3.8E-20 T 23-10-2018 A3L01_10170 4fca4f7b4a4cdb80faa72b3a9042c828 269 SUPERFAMILY SSF56784 3 259 1.49E-68 T 23-10-2018 IPR036412 HAD-like superfamily A3L01_10170 4fca4f7b4a4cdb80faa72b3a9042c828 269 Gene3D G3DSA:3.40.50.1000 69 185 1.0E-92 T 23-10-2018 IPR023214 HAD superfamily A3L01_10170 4fca4f7b4a4cdb80faa72b3a9042c828 269 Pfam PF13344 Haloacid dehalogenase-like hydrolase 4 103 1.4E-28 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A3L01_05420 6123164287165c925395d6d0c134db7c 513 SUPERFAMILY SSF51717 162 386 1.31E-23 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L01_05420 6123164287165c925395d6d0c134db7c 513 TIGRFAM TIGR00284 TIGR00284: dihydropteroate synthase-related protein 6 504 1.8E-95 T 23-10-2018 IPR005236 Dihydropteroate synthase-related protein synthase-related protein A3L01_00835 1996b8105abcb5d398660313d2504038 336 SUPERFAMILY SSF55347 156 314 5.43E-39 T 23-10-2018 A3L01_00835 1996b8105abcb5d398660313d2504038 336 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 201 223 - T 23-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A3L01_00835 1996b8105abcb5d398660313d2504038 336 Pfam PF00742 Homoserine dehydrogenase 156 327 1.8E-48 T 23-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A3L01_00835 1996b8105abcb5d398660313d2504038 336 Gene3D G3DSA:3.40.50.720 7 327 2.5E-95 T 23-10-2018 A3L01_00835 1996b8105abcb5d398660313d2504038 336 PIRSF PIRSF036497 1 335 2.7E-87 T 23-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A3L01_00835 1996b8105abcb5d398660313d2504038 336 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 147 1.4E-9 T 23-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 A3L01_00835 1996b8105abcb5d398660313d2504038 336 SUPERFAMILY SSF51735 2 177 7.21E-32 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_00835 1996b8105abcb5d398660313d2504038 336 Gene3D G3DSA:3.30.360.10 167 310 2.5E-95 T 23-10-2018 A3L01_06695 5727801605a425865cd5d872ccd28ae0 429 Gene3D G3DSA:3.40.190.10 28 423 5.9E-51 T 23-10-2018 A3L01_06695 5727801605a425865cd5d872ccd28ae0 429 SUPERFAMILY SSF53850 22 413 6.27E-57 T 23-10-2018 A3L01_06695 5727801605a425865cd5d872ccd28ae0 429 Pfam PF13416 Bacterial extracellular solute-binding protein 54 349 2.8E-40 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein A3L01_02975 263bc3ed3b0234da905a30e2f6dfb1a5 110 Gene3D G3DSA:3.30.300.100 1 110 1.5E-42 T 23-10-2018 IPR035954 MTH677-like superfamily A3L01_02975 263bc3ed3b0234da905a30e2f6dfb1a5 110 Pfam PF11419 Protein of unknown function (DUF3194) 15 97 1.1E-26 T 23-10-2018 IPR024502 Protein of unknown function DUF3194 A3L01_02975 263bc3ed3b0234da905a30e2f6dfb1a5 110 SUPERFAMILY SSF110783 15 99 4.05E-5 T 23-10-2018 IPR035954 MTH677-like superfamily A3L01_03550 81fdb91cd52345a16ba410b3dc7e8f19 534 Pfam PF16861 Carbamoyltransferase C-terminus 364 533 8.3E-61 T 23-10-2018 IPR031730 Carbamoyltransferase, C-terminal A3L01_03550 81fdb91cd52345a16ba410b3dc7e8f19 534 SUPERFAMILY SSF53067 8 314 2.33E-12 T 23-10-2018 A3L01_03550 81fdb91cd52345a16ba410b3dc7e8f19 534 Gene3D G3DSA:3.30.420.40 9 312 1.7E-64 T 23-10-2018 A3L01_03550 81fdb91cd52345a16ba410b3dc7e8f19 534 Gene3D G3DSA:3.90.870.20 330 533 4.8E-70 T 23-10-2018 IPR038152 Carbamoyltransferase, C-terminal domain superfamily A3L01_03550 81fdb91cd52345a16ba410b3dc7e8f19 534 Gene3D G3DSA:3.30.420.350 95 305 1.7E-64 T 23-10-2018 A3L01_03550 81fdb91cd52345a16ba410b3dc7e8f19 534 Pfam PF02543 Carbamoyltransferase N-terminus 87 312 1.5E-36 T 23-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 A3L01_03550 81fdb91cd52345a16ba410b3dc7e8f19 534 Pfam PF02543 Carbamoyltransferase N-terminus 2 70 3.4E-8 T 23-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 A3L01_05700 ebcfd8d3526fa040120465e957a945a1 612 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 305 5.6E-13 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_05700 ebcfd8d3526fa040120465e957a945a1 612 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 417 601 6.3E-16 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_05700 ebcfd8d3526fa040120465e957a945a1 612 SUPERFAMILY SSF161098 333 605 9.35E-41 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_05700 ebcfd8d3526fa040120465e957a945a1 612 Gene3D G3DSA:1.10.3720.10 330 599 2.1E-36 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_05700 ebcfd8d3526fa040120465e957a945a1 612 SUPERFAMILY SSF161098 23 312 4.21E-43 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_05700 ebcfd8d3526fa040120465e957a945a1 612 Gene3D G3DSA:1.10.3720.10 19 318 1.0E-49 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_04205 e70ecefe66a4a0e167b24f11fd919035 483 Gene3D G3DSA:3.40.50.300 3 241 1.7E-46 T 23-10-2018 A3L01_04205 e70ecefe66a4a0e167b24f11fd919035 483 SUPERFAMILY SSF52540 1 236 2.07E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_04205 e70ecefe66a4a0e167b24f11fd919035 483 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 250 432 2.4E-49 T 23-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 A3L01_04205 e70ecefe66a4a0e167b24f11fd919035 483 Gene3D G3DSA:3.40.50.880 247 400 3.4E-15 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_04205 e70ecefe66a4a0e167b24f11fd919035 483 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 229 3.8E-21 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L01_04205 e70ecefe66a4a0e167b24f11fd919035 483 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 476 2.9E-154 T 23-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 A3L01_04205 e70ecefe66a4a0e167b24f11fd919035 483 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 483 156.428 T 23-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 A3L01_04205 e70ecefe66a4a0e167b24f11fd919035 483 SUPERFAMILY SSF52317 192 367 4.89E-28 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_04050 91aabb434722f3901ab2300a20811166 413 Gene3D G3DSA:3.90.550.10 1 238 1.5E-72 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_04050 91aabb434722f3901ab2300a20811166 413 Pfam PF00483 Nucleotidyl transferase 2 231 2.7E-44 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L01_04050 91aabb434722f3901ab2300a20811166 413 Gene3D G3DSA:2.160.10.10 239 371 1.7E-17 T 23-10-2018 A3L01_04050 91aabb434722f3901ab2300a20811166 413 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 313 346 1.3E-4 T 23-10-2018 IPR001451 Hexapeptide repeat A3L01_04050 91aabb434722f3901ab2300a20811166 413 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 261 287 1.4E-4 T 23-10-2018 IPR001451 Hexapeptide repeat A3L01_04050 91aabb434722f3901ab2300a20811166 413 SUPERFAMILY SSF53448 1 299 8.21E-72 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_08440 52af87ae744ea5eba8d3ff59032ce54a 559 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 247 255 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 A3L01_08440 52af87ae744ea5eba8d3ff59032ce54a 559 SUPERFAMILY SSF56091 219 422 9.59E-55 T 23-10-2018 A3L01_08440 52af87ae744ea5eba8d3ff59032ce54a 559 Gene3D G3DSA:3.30.470.30 221 422 3.6E-73 T 23-10-2018 A3L01_08440 52af87ae744ea5eba8d3ff59032ce54a 559 Gene3D G3DSA:2.40.50.140 423 559 3.6E-52 T 23-10-2018 A3L01_08440 52af87ae744ea5eba8d3ff59032ce54a 559 Hamap MF_00407 DNA ligase [lig]. 1 550 34.5 T 23-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 A3L01_08440 52af87ae744ea5eba8d3ff59032ce54a 559 Pfam PF04679 ATP dependent DNA ligase C terminal region 443 534 2.9E-20 T 23-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 A3L01_08440 52af87ae744ea5eba8d3ff59032ce54a 559 Pfam PF04675 DNA ligase N terminus 3 176 1.2E-38 T 23-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 A3L01_08440 52af87ae744ea5eba8d3ff59032ce54a 559 Gene3D G3DSA:1.10.3260.10 1 220 4.9E-85 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 A3L01_08440 52af87ae744ea5eba8d3ff59032ce54a 559 SUPERFAMILY SSF50249 425 552 1.83E-40 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_08440 52af87ae744ea5eba8d3ff59032ce54a 559 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 398 422 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 A3L01_08440 52af87ae744ea5eba8d3ff59032ce54a 559 Pfam PF01068 ATP dependent DNA ligase domain 224 422 2.0E-63 T 23-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 A3L01_08440 52af87ae744ea5eba8d3ff59032ce54a 559 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 57 550 7.6E-163 T 23-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 A3L01_08440 52af87ae744ea5eba8d3ff59032ce54a 559 SUPERFAMILY SSF117018 2 242 6.54E-70 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 A3L01_02665 55da859d33696956d64965e86b26a464 267 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 222 2.7E-49 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L01_02665 55da859d33696956d64965e86b26a464 267 PIRSF PIRSF001430 1 243 1.9E-73 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L01_02665 55da859d33696956d64965e86b26a464 267 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 227 29.624 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L01_02665 55da859d33696956d64965e86b26a464 267 Gene3D G3DSA:3.30.70.580 1 103 9.2E-25 T 23-10-2018 A3L01_02665 55da859d33696956d64965e86b26a464 267 Gene3D G3DSA:3.30.70.660 104 226 8.3E-22 T 23-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 A3L01_02665 55da859d33696956d64965e86b26a464 267 SUPERFAMILY SSF55120 1 232 2.01E-62 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L01_02665 55da859d33696956d64965e86b26a464 267 Pfam PF01416 tRNA pseudouridine synthase 129 228 5.9E-19 T 23-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 Gene3D G3DSA:2.20.28.10 132 177 2.9E-28 T 23-10-2018 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 SUPERFAMILY SSF47413 701 754 8.16E-9 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 Gene3D G3DSA:3.10.28.10 478 567 3.0E-5 T 23-10-2018 IPR027434 Homing endonuclease A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 SMART SM00530 705 756 5.2E-6 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 SUPERFAMILY SSF51294 335 808 5.4E-44 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 SUPERFAMILY SSF50249 10 248 2.23E-62 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 SMART SM00306 334 457 5.1E-31 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 787 809 6.7E-9 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 Gene3D G3DSA:2.40.50.140 178 257 3.7E-27 T 23-10-2018 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 SUPERFAMILY SSF55608 578 684 4.0E-17 T 23-10-2018 IPR027434 Homing endonuclease A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 Gene3D G3DSA:3.40.50.300 792 1070 9.3E-112 T 23-10-2018 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 Gene3D G3DSA:3.40.50.300 263 336 1.3E-23 T 23-10-2018 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 PRINTS PR00379 Intein signature 785 802 1.7E-20 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 PRINTS PR00379 Intein signature 493 505 1.7E-20 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 PRINTS PR00379 Intein signature 592 604 1.7E-20 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 PRINTS PR00379 Intein signature 420 433 1.7E-20 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 PRINTS PR00379 Intein signature 620 635 1.7E-20 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 PRINTS PR00379 Intein signature 803 812 1.7E-20 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 Pfam PF14890 Intein splicing domain 343 808 5.5E-40 T 23-10-2018 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 SMART SM00350 101 1067 1.7E-135 T 23-10-2018 IPR031327 Mini-chromosome maintenance protein A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 Gene3D G3DSA:3.10.28.10 576 693 1.6E-27 T 23-10-2018 IPR027434 Homing endonuclease A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 Gene3D G3DSA:3.30.1640.10 1 100 6.9E-38 T 23-10-2018 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 Gene3D G3DSA:1.10.260.40 694 778 1.0E-7 T 23-10-2018 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 Gene3D G3DSA:2.170.16.10 337 477 4.5E-36 T 23-10-2018 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 SMART SM00305 767 814 7.6E-16 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 SUPERFAMILY SSF55608 492 565 1.4E-6 T 23-10-2018 IPR027434 Homing endonuclease A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 336 433 1.1E-21 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 Pfam PF17207 MCM OB domain 105 230 4.2E-36 T 23-10-2018 IPR033762 MCM OB domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 Pfam PF14551 MCM N-terminal domain 8 93 1.5E-11 T 23-10-2018 IPR027925 MCM N-terminal domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 Gene3D G3DSA:1.10.10.10 1071 1156 3.7E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 Pfam PF14528 LAGLIDADG-like domain 496 565 2.2E-6 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 Pfam PF14528 LAGLIDADG-like domain 591 673 5.4E-20 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 SUPERFAMILY SSF52540 809 1064 4.17E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 Pfam PF00493 MCM2/3/5 family 266 336 1.7E-22 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 Pfam PF00493 MCM2/3/5 family 802 1066 4.9E-107 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L01_00870 0c78e2d61e1b64f966a1f84cb5dbfc1c 1156 Pfam PF01381 Helix-turn-helix 706 755 1.5E-6 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L01_09670 93876ebeca01aeaafef82018c1cef280 460 PIRSF PIRSF000521 1 142 3.2E-10 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L01_09670 93876ebeca01aeaafef82018c1cef280 460 PIRSF PIRSF000521 138 447 3.6E-34 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L01_09670 93876ebeca01aeaafef82018c1cef280 460 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 261 298 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L01_09670 93876ebeca01aeaafef82018c1cef280 460 Gene3D G3DSA:3.40.640.10 73 344 6.7E-142 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L01_09670 93876ebeca01aeaafef82018c1cef280 460 Gene3D G3DSA:3.90.1150.10 19 440 6.7E-142 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L01_09670 93876ebeca01aeaafef82018c1cef280 460 SUPERFAMILY SSF53383 34 445 1.24E-116 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L01_09670 93876ebeca01aeaafef82018c1cef280 460 Pfam PF00202 Aminotransferase class-III 37 444 2.4E-101 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L01_06270 a409e712822a1bf21cf01557ad9f9da4 150 Gene3D G3DSA:1.10.10.2700 1 150 2.4E-65 T 23-10-2018 IPR038111 Ribosomal protein S19e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06270 a409e712822a1bf21cf01557ad9f9da4 150 ProDom PD003854 RIBOSOMAL 40S RIBONUCLEOPROTEIN S19 S19E 30S MULTIGENE FAMILY S19 SSU 3 115 4.0E-58 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06270 a409e712822a1bf21cf01557ad9f9da4 150 SUPERFAMILY SSF46785 3 150 5.46E-61 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_06270 a409e712822a1bf21cf01557ad9f9da4 150 Pfam PF01090 Ribosomal protein S19e 3 138 3.6E-58 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06270 a409e712822a1bf21cf01557ad9f9da4 150 Hamap MF_01474 30S ribosomal protein S19e [rps19e]. 1 148 37.732 T 23-10-2018 IPR027548 Ribosomal protein S19e, archaeal GO:0003735|GO:0005840|GO:0006412 A3L01_06270 a409e712822a1bf21cf01557ad9f9da4 150 SMART SM01413 3 139 8.5E-91 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06270 a409e712822a1bf21cf01557ad9f9da4 150 ProSitePatterns PS00628 Ribosomal protein S19e signature. 87 106 - T 23-10-2018 IPR018277 Ribosomal protein S19e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06210 39969ab694fac577da562482e657925d 400 SUPERFAMILY SSF63882 7 180 8.63E-56 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L01_06210 39969ab694fac577da562482e657925d 400 SUPERFAMILY SSF53218 181 325 2.62E-43 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L01_06210 39969ab694fac577da562482e657925d 400 Pfam PF00994 Probable molybdopterin binding domain 184 320 6.4E-25 T 23-10-2018 IPR001453 MoaB/Mog domain A3L01_06210 39969ab694fac577da562482e657925d 400 Gene3D G3DSA:3.40.980.10 179 320 6.6E-114 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L01_06210 39969ab694fac577da562482e657925d 400 SMART SM00852 184 321 5.5E-40 T 23-10-2018 IPR001453 MoaB/Mog domain A3L01_06210 39969ab694fac577da562482e657925d 400 Gene3D G3DSA:2.40.340.10 329 400 2.1E-24 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L01_06210 39969ab694fac577da562482e657925d 400 Pfam PF03453 MoeA N-terminal region (domain I and II) 8 171 3.7E-42 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L01_06210 39969ab694fac577da562482e657925d 400 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 181 317 2.5E-33 T 23-10-2018 IPR001453 MoaB/Mog domain A3L01_06210 39969ab694fac577da562482e657925d 400 Gene3D G3DSA:3.90.105.10 26 178 6.6E-114 T 23-10-2018 A3L01_06210 39969ab694fac577da562482e657925d 400 Pfam PF03454 MoeA C-terminal region (domain IV) 335 399 5.2E-17 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L01_06210 39969ab694fac577da562482e657925d 400 SUPERFAMILY SSF63867 331 399 1.7E-17 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L01_06210 39969ab694fac577da562482e657925d 400 Gene3D G3DSA:2.170.190.11 49 145 6.6E-114 T 23-10-2018 A3L01_09540 fe560221e15f911173ccbd6c56e655d8 652 Pfam PF09094 Domain of unknown function (DUF1925) 309 380 6.6E-36 T 23-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain A3L01_09540 fe560221e15f911173ccbd6c56e655d8 652 Pfam PF03065 Glycosyl hydrolase family 57 5 288 4.2E-67 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A3L01_09540 fe560221e15f911173ccbd6c56e655d8 652 Gene3D G3DSA:2.70.98.10 386 652 2.2E-85 T 23-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A3L01_09540 fe560221e15f911173ccbd6c56e655d8 652 SUPERFAMILY SSF88688 309 381 2.35E-36 T 23-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily A3L01_09540 fe560221e15f911173ccbd6c56e655d8 652 Pfam PF09095 Domain of unknown function (DUF1926) 390 647 3.7E-76 T 23-10-2018 IPR015179 Alpha-amylase/4-alpha-glucanotransferase, C-terminal GO:0003824|GO:0005975|GO:0030246 A3L01_09540 fe560221e15f911173ccbd6c56e655d8 652 Gene3D G3DSA:3.20.110.20 1 379 5.6E-179 T 23-10-2018 A3L01_09540 fe560221e15f911173ccbd6c56e655d8 652 SUPERFAMILY SSF88713 3 307 1.11E-70 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L01_09540 fe560221e15f911173ccbd6c56e655d8 652 SUPERFAMILY SSF74650 386 651 1.26E-96 T 23-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 A3L01_09540 fe560221e15f911173ccbd6c56e655d8 652 ProDom PD014405 HYDROLASE METABOLISM CARBOHYDRATE GLYCOSIDASE ALPHA-AMYLASE TRANSFERASE 4-ALPHA-GLUCANOTRANSFERASE GLYCOSYLTRANSFERASE FAMILY DIRECT 317 382 7.0E-30 T 23-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain A3L01_01635 a126d0ee926665588d55c37bcfa684ab 246 SUPERFAMILY SSF159713 8 243 1.29E-60 T 23-10-2018 A3L01_01635 a126d0ee926665588d55c37bcfa684ab 246 Gene3D G3DSA:3.30.390.100 12 221 6.6E-26 T 23-10-2018 A3L01_01635 a126d0ee926665588d55c37bcfa684ab 246 Pfam PF13938 Putative heavy-metal chelation 9 90 3.2E-14 T 23-10-2018 IPR025251 Domain of unknown function DUF4213 A3L01_01635 a126d0ee926665588d55c37bcfa684ab 246 Gene3D G3DSA:3.40.50.11590 105 216 6.6E-26 T 23-10-2018 A3L01_01635 a126d0ee926665588d55c37bcfa684ab 246 Pfam PF04016 Putative heavy-metal chelation 110 233 1.9E-31 T 23-10-2018 IPR007161 Putative heavy-metal chelation domain A3L01_02380 a063b296a3ea29ea9e1409566506bab6 214 Gene3D G3DSA:1.10.150.520 15 86 2.0E-48 T 23-10-2018 A3L01_02380 a063b296a3ea29ea9e1409566506bab6 214 SUPERFAMILY SSF56784 1 211 2.67E-49 T 23-10-2018 IPR036412 HAD-like superfamily A3L01_02380 a063b296a3ea29ea9e1409566506bab6 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 98 111 8.5E-17 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_02380 a063b296a3ea29ea9e1409566506bab6 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 8.5E-17 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_02380 a063b296a3ea29ea9e1409566506bab6 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 174 187 8.5E-17 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_02380 a063b296a3ea29ea9e1409566506bab6 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 144 8.5E-17 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_02380 a063b296a3ea29ea9e1409566506bab6 214 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 2 206 2.4E-53 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 A3L01_02380 a063b296a3ea29ea9e1409566506bab6 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 185 1.8E-30 T 23-10-2018 A3L01_02380 a063b296a3ea29ea9e1409566506bab6 214 Gene3D G3DSA:3.40.50.1000 3 206 2.0E-48 T 23-10-2018 IPR023214 HAD superfamily A3L01_02380 a063b296a3ea29ea9e1409566506bab6 214 ProSitePatterns PS01228 Hypothetical cof family signature 1. 3 14 - T 23-10-2018 A3L01_02380 a063b296a3ea29ea9e1409566506bab6 214 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 99 179 5.3E-14 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_02380 a063b296a3ea29ea9e1409566506bab6 214 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 82 185 1.0E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_08160 6f9830fcff0583f3c564503ad81f5d57 110 Gene3D G3DSA:2.20.70.30 10 69 3.7E-23 T 23-10-2018 IPR038187 NAC A/B domain superfamily A3L01_08160 6f9830fcff0583f3c564503ad81f5d57 110 SMART SM01407 6 65 3.1E-19 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain A3L01_08160 6f9830fcff0583f3c564503ad81f5d57 110 Pfam PF01849 NAC domain 6 63 3.6E-14 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain A3L01_08160 6f9830fcff0583f3c564503ad81f5d57 110 Hamap MF_00814 Nascent polypeptide-associated complex protein [nac]. 7 108 21.534 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 A3L01_08160 6f9830fcff0583f3c564503ad81f5d57 110 SUPERFAMILY SSF46934 69 107 1.53E-8 T 23-10-2018 IPR009060 UBA-like superfamily GO:0005515 A3L01_08160 6f9830fcff0583f3c564503ad81f5d57 110 Gene3D G3DSA:1.10.8.10 70 108 7.1E-21 T 23-10-2018 A3L01_08160 6f9830fcff0583f3c564503ad81f5d57 110 TIGRFAM TIGR00264 TIGR00264: alpha-NAC homolog 3 108 1.9E-37 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 A3L01_02260 86ffc9df5c07004ae264462bc0b54537 226 Gene3D G3DSA:3.40.30.10 1 117 1.2E-35 T 23-10-2018 A3L01_02260 86ffc9df5c07004ae264462bc0b54537 226 SUPERFAMILY SSF52833 121 221 1.81E-20 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L01_02260 86ffc9df5c07004ae264462bc0b54537 226 TIGRFAM TIGR02187 GlrX_arch: glutaredoxin-like domain protein 4 223 5.7E-87 T 23-10-2018 IPR011903 Glutaredoxin-like domain A3L01_02260 86ffc9df5c07004ae264462bc0b54537 226 Gene3D G3DSA:3.40.30.10 120 225 1.2E-26 T 23-10-2018 A3L01_02260 86ffc9df5c07004ae264462bc0b54537 226 Pfam PF13192 Thioredoxin domain 137 222 6.3E-15 T 23-10-2018 IPR012336 Thioredoxin-like fold A3L01_02260 86ffc9df5c07004ae264462bc0b54537 226 SUPERFAMILY SSF52833 5 117 1.91E-25 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L01_10225 581e1fa934b282cf80611a7aadc505a2 385 Gene3D G3DSA:3.40.50.2000 181 362 6.6E-49 T 23-10-2018 A3L01_10225 581e1fa934b282cf80611a7aadc505a2 385 SUPERFAMILY SSF53756 2 374 3.68E-53 T 23-10-2018 A3L01_10225 581e1fa934b282cf80611a7aadc505a2 385 Gene3D G3DSA:3.40.50.2000 13 373 6.6E-49 T 23-10-2018 A3L01_10225 581e1fa934b282cf80611a7aadc505a2 385 Pfam PF00534 Glycosyl transferases group 1 191 349 1.4E-27 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L01_03570 26290c12b55e7e421650e2a014308d2f 331 Gene3D G3DSA:2.40.30.40 64 155 6.9E-114 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A3L01_03570 26290c12b55e7e421650e2a014308d2f 331 SUPERFAMILY SSF101821 65 172 4.43E-21 T 23-10-2018 A3L01_03570 26290c12b55e7e421650e2a014308d2f 331 Gene3D G3DSA:3.40.630.10 8 324 6.9E-114 T 23-10-2018 A3L01_03570 26290c12b55e7e421650e2a014308d2f 331 SUPERFAMILY SSF53187 2 330 1.49E-54 T 23-10-2018 A3L01_03570 26290c12b55e7e421650e2a014308d2f 331 PIRSF PIRSF001123 1 331 4.1E-86 T 23-10-2018 IPR008007 Peptidase M42 A3L01_03570 26290c12b55e7e421650e2a014308d2f 331 Pfam PF05343 M42 glutamyl aminopeptidase 42 323 2.4E-84 T 23-10-2018 IPR008007 Peptidase M42 A3L01_01070 263413d51d4451978f83c05472aec5a0 98 PIRSF PIRSF037511 5 97 1.7E-25 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 A3L01_01070 263413d51d4451978f83c05472aec5a0 98 Hamap MF_00604 Protein translation factor SUI1 homolog. 2 93 26.534 T 23-10-2018 IPR022851 Translation factor SUI1 homolog, archaea A3L01_01070 263413d51d4451978f83c05472aec5a0 98 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 4 97 9.3E-36 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 A3L01_01070 263413d51d4451978f83c05472aec5a0 98 SUPERFAMILY SSF55159 5 90 5.75E-24 T 23-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 A3L01_01070 263413d51d4451978f83c05472aec5a0 98 Gene3D G3DSA:3.30.780.10 20 98 1.4E-28 T 23-10-2018 A3L01_01070 263413d51d4451978f83c05472aec5a0 98 Pfam PF01253 Translation initiation factor SUI1 20 89 2.6E-20 T 23-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 A3L01_09230 2e2a71aad7a4c9fb13e9002840f6359d 357 SUPERFAMILY SSF52540 4 168 1.27E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_09230 2e2a71aad7a4c9fb13e9002840f6359d 357 Gene3D G3DSA:1.10.1580.10 169 252 3.9E-14 T 23-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily A3L01_09230 2e2a71aad7a4c9fb13e9002840f6359d 357 Gene3D G3DSA:3.40.50.300 5 162 1.0E-45 T 23-10-2018 A3L01_09230 2e2a71aad7a4c9fb13e9002840f6359d 357 Pfam PF01926 50S ribosome-binding GTPase 107 162 7.8E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_02420 a398f0b8bacc6cc7ac03135c39f53731 416 Gene3D G3DSA:1.10.1510.30 171 256 7.2E-116 T 23-10-2018 A3L01_02420 a398f0b8bacc6cc7ac03135c39f53731 416 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 12 415 4.1E-82 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L01_02420 a398f0b8bacc6cc7ac03135c39f53731 416 PIRSF PIRSF037016 32 393 1.3E-57 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L01_02420 a398f0b8bacc6cc7ac03135c39f53731 416 PIRSF PIRSF037016 388 416 0.016 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L01_02420 a398f0b8bacc6cc7ac03135c39f53731 416 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 8 416 29.353 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L01_02420 a398f0b8bacc6cc7ac03135c39f53731 416 Gene3D G3DSA:3.30.2350.20 126 411 7.2E-116 T 23-10-2018 A3L01_02420 a398f0b8bacc6cc7ac03135c39f53731 416 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 11 412 2.2E-134 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L01_02420 a398f0b8bacc6cc7ac03135c39f53731 416 Gene3D G3DSA:3.30.70.3160 43 125 7.2E-116 T 23-10-2018 A3L01_02420 a398f0b8bacc6cc7ac03135c39f53731 416 SUPERFAMILY SSF55120 7 414 5.32E-92 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L01_02420 a398f0b8bacc6cc7ac03135c39f53731 416 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 80 93 - T 23-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 A3L01_00275 fd54cb5f325127e8eed4fcf6c85eda0d 181 Pfam PF06510 Protein of unknown function (DUF1102) 38 176 4.2E-45 T 23-10-2018 IPR009482 Protein of unknown function DUF1102 A3L01_06805 bba113d888b6b1889e7e86d911e35088 303 Pfam PF00382 Transcription factor TFIIB repeat 216 286 1.7E-19 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A3L01_06805 bba113d888b6b1889e7e86d911e35088 303 Pfam PF00382 Transcription factor TFIIB repeat 123 192 7.6E-19 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A3L01_06805 bba113d888b6b1889e7e86d911e35088 303 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 1 301 45.611 T 23-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea A3L01_06805 bba113d888b6b1889e7e86d911e35088 303 PRINTS PR00685 Transcription initiation factor IIB signature 281 295 1.9E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L01_06805 bba113d888b6b1889e7e86d911e35088 303 PRINTS PR00685 Transcription initiation factor IIB signature 162 181 1.9E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L01_06805 bba113d888b6b1889e7e86d911e35088 303 PRINTS PR00685 Transcription initiation factor IIB signature 19 39 1.9E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L01_06805 bba113d888b6b1889e7e86d911e35088 303 PRINTS PR00685 Transcription initiation factor IIB signature 41 54 1.9E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L01_06805 bba113d888b6b1889e7e86d911e35088 303 PRINTS PR00685 Transcription initiation factor IIB signature 54 75 1.9E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L01_06805 bba113d888b6b1889e7e86d911e35088 303 PRINTS PR00685 Transcription initiation factor IIB signature 188 203 1.9E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L01_06805 bba113d888b6b1889e7e86d911e35088 303 PRINTS PR00685 Transcription initiation factor IIB signature 215 233 1.9E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L01_06805 bba113d888b6b1889e7e86d911e35088 303 PRINTS PR00685 Transcription initiation factor IIB signature 249 265 1.9E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L01_06805 bba113d888b6b1889e7e86d911e35088 303 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 248 263 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L01_06805 bba113d888b6b1889e7e86d911e35088 303 SMART SM00385 214 295 1.3E-10 T 23-10-2018 IPR013763 Cyclin-like A3L01_06805 bba113d888b6b1889e7e86d911e35088 303 SMART SM00385 120 201 3.8E-12 T 23-10-2018 IPR013763 Cyclin-like A3L01_06805 bba113d888b6b1889e7e86d911e35088 303 SUPERFAMILY SSF57783 5 50 1.12E-16 T 23-10-2018 A3L01_06805 bba113d888b6b1889e7e86d911e35088 303 Pfam PF08271 TFIIB zinc-binding 6 47 4.3E-18 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type A3L01_06805 bba113d888b6b1889e7e86d911e35088 303 SUPERFAMILY SSF47954 114 207 2.51E-24 T 23-10-2018 IPR036915 Cyclin-like superfamily A3L01_06805 bba113d888b6b1889e7e86d911e35088 303 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 154 169 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L01_06805 bba113d888b6b1889e7e86d911e35088 303 SUPERFAMILY SSF47954 211 302 1.09E-29 T 23-10-2018 IPR036915 Cyclin-like superfamily A3L01_06805 bba113d888b6b1889e7e86d911e35088 303 Gene3D G3DSA:1.10.472.10 211 303 5.0E-27 T 23-10-2018 A3L01_06805 bba113d888b6b1889e7e86d911e35088 303 Gene3D G3DSA:1.10.472.170 6 202 2.2E-65 T 23-10-2018 A3L01_03390 7b66a3e254b0cc8e52f0866d33b69b39 635 Gene3D G3DSA:3.30.230.10 432 635 7.5E-80 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L01_03390 7b66a3e254b0cc8e52f0866d33b69b39 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 517 536 1.3E-29 T 23-10-2018 A3L01_03390 7b66a3e254b0cc8e52f0866d33b69b39 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 67 86 1.3E-29 T 23-10-2018 A3L01_03390 7b66a3e254b0cc8e52f0866d33b69b39 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 570 588 1.3E-29 T 23-10-2018 A3L01_03390 7b66a3e254b0cc8e52f0866d33b69b39 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 440 456 1.3E-29 T 23-10-2018 A3L01_03390 7b66a3e254b0cc8e52f0866d33b69b39 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 547 566 1.3E-29 T 23-10-2018 A3L01_03390 7b66a3e254b0cc8e52f0866d33b69b39 635 SMART SM00382 59 289 8.1E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_03390 7b66a3e254b0cc8e52f0866d33b69b39 635 Gene3D G3DSA:1.10.8.60 321 413 3.6E-44 T 23-10-2018 A3L01_03390 7b66a3e254b0cc8e52f0866d33b69b39 635 TIGRFAM TIGR00764 lon_rel: putative ATP-dependent protease 24 629 0.0 T 23-10-2018 IPR004663 Lon protease, archaeal GO:0004176|GO:0005524|GO:0030163 A3L01_03390 7b66a3e254b0cc8e52f0866d33b69b39 635 SUPERFAMILY SSF54211 440 613 2.35E-44 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L01_03390 7b66a3e254b0cc8e52f0866d33b69b39 635 Gene3D G3DSA:3.40.50.300 20 132 1.8E-31 T 23-10-2018 A3L01_03390 7b66a3e254b0cc8e52f0866d33b69b39 635 Gene3D G3DSA:3.40.50.300 162 320 4.7E-43 T 23-10-2018 A3L01_03390 7b66a3e254b0cc8e52f0866d33b69b39 635 SUPERFAMILY SSF52540 36 414 2.17E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_03390 7b66a3e254b0cc8e52f0866d33b69b39 635 Pfam PF13654 AAA domain 183 411 6.0E-23 T 23-10-2018 A3L01_03390 7b66a3e254b0cc8e52f0866d33b69b39 635 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 434 615 1.3E-36 T 23-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A3L01_03390 7b66a3e254b0cc8e52f0866d33b69b39 635 Pfam PF01078 Magnesium chelatase, subunit ChlI 41 93 1.6E-9 T 23-10-2018 IPR000523 Magnesium chelatase ChlI domain A3L01_06785 f7cef38e91091b7f40aa1820fb73dd5a 193 SUPERFAMILY SSF52540 6 144 1.56E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06785 f7cef38e91091b7f40aa1820fb73dd5a 193 SUPERFAMILY SSF57716 145 192 3.56E-16 T 23-10-2018 A3L01_06785 f7cef38e91091b7f40aa1820fb73dd5a 193 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 177 190 - T 23-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A3L01_06785 f7cef38e91091b7f40aa1820fb73dd5a 193 Gene3D G3DSA:3.40.50.300 1 144 3.1E-46 T 23-10-2018 A3L01_06785 f7cef38e91091b7f40aa1820fb73dd5a 193 PIRSF PIRSF035805 4 193 5.1E-66 T 23-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A3L01_06785 f7cef38e91091b7f40aa1820fb73dd5a 193 Pfam PF00265 Thymidine kinase 7 190 1.1E-53 T 23-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A3L01_06785 f7cef38e91091b7f40aa1820fb73dd5a 193 Hamap MF_00124 Thymidine kinase [tdk]. 5 193 36.097 T 23-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A3L01_06785 f7cef38e91091b7f40aa1820fb73dd5a 193 Gene3D G3DSA:3.30.60.20 145 193 1.7E-24 T 23-10-2018 A3L01_06040 822104ace477b0bc3b7f01e3aa2c18c3 503 Pfam PF02885 Glycosyl transferase family, helical bundle domain 89 150 4.4E-14 T 23-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L01_06040 822104ace477b0bc3b7f01e3aa2c18c3 503 TIGRFAM TIGR03327 AMP_phos: AMP phosphorylase 3 500 8.0E-243 T 23-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 A3L01_06040 822104ace477b0bc3b7f01e3aa2c18c3 503 Gene3D G3DSA:1.20.970.10 84 151 3.4E-23 T 23-10-2018 A3L01_06040 822104ace477b0bc3b7f01e3aa2c18c3 503 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 424 487 3.9E-13 T 23-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L01_06040 822104ace477b0bc3b7f01e3aa2c18c3 503 Gene3D G3DSA:3.40.1030.10 152 412 1.4E-101 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L01_06040 822104ace477b0bc3b7f01e3aa2c18c3 503 Hamap MF_02132 AMP phosphorylase. 1 503 46.723 T 23-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 A3L01_06040 822104ace477b0bc3b7f01e3aa2c18c3 503 SUPERFAMILY SSF47648 86 153 1.7E-15 T 23-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L01_06040 822104ace477b0bc3b7f01e3aa2c18c3 503 Pfam PF00591 Glycosyl transferase family, a/b domain 158 387 2.8E-13 T 23-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L01_06040 822104ace477b0bc3b7f01e3aa2c18c3 503 Gene3D G3DSA:2.40.40.20 1 83 8.2E-39 T 23-10-2018 A3L01_06040 822104ace477b0bc3b7f01e3aa2c18c3 503 Gene3D G3DSA:3.90.1170.30 413 493 2.2E-27 T 23-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L01_06040 822104ace477b0bc3b7f01e3aa2c18c3 503 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 4 494 8.7E-226 T 23-10-2018 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 A3L01_06040 822104ace477b0bc3b7f01e3aa2c18c3 503 PIRSF PIRSF000478 84 502 3.0E-121 T 23-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L01_06040 822104ace477b0bc3b7f01e3aa2c18c3 503 SUPERFAMILY SSF52418 155 404 2.88E-68 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L01_06040 822104ace477b0bc3b7f01e3aa2c18c3 503 SMART SM00941 424 491 1.1E-22 T 23-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L01_06040 822104ace477b0bc3b7f01e3aa2c18c3 503 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 193 208 - T 23-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L01_06040 822104ace477b0bc3b7f01e3aa2c18c3 503 SUPERFAMILY SSF54680 412 495 1.11E-16 T 23-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L01_09765 472f7e89cf3996aee0dcd74c05eb1ebc 214 Pfam PF03729 Short repeat of unknown function (DUF308) 46 117 1.1E-10 T 23-10-2018 IPR005325 Protein of unknown function DUF308, membrane A3L01_03130 98eeb43c0a1b412909bb33c6bee7a4be 447 Gene3D G3DSA:3.90.1150.10 8 425 6.3E-147 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L01_03130 98eeb43c0a1b412909bb33c6bee7a4be 447 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 245 282 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L01_03130 98eeb43c0a1b412909bb33c6bee7a4be 447 SUPERFAMILY SSF53383 24 430 1.53E-127 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L01_03130 98eeb43c0a1b412909bb33c6bee7a4be 447 Gene3D G3DSA:3.40.640.10 63 327 6.3E-147 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L01_03130 98eeb43c0a1b412909bb33c6bee7a4be 447 Pfam PF00202 Aminotransferase class-III 26 428 2.3E-112 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L01_03130 98eeb43c0a1b412909bb33c6bee7a4be 447 PIRSF PIRSF000521 126 431 9.6E-32 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L01_03130 98eeb43c0a1b412909bb33c6bee7a4be 447 PIRSF PIRSF000521 32 133 1.1E-6 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L01_02270 848b1ba02d797be5e1566576aaaee5df 85 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 85 16.798 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 A3L01_02270 848b1ba02d797be5e1566576aaaee5df 85 SUPERFAMILY SSF143430 1 81 2.88E-25 T 23-10-2018 A3L01_02270 848b1ba02d797be5e1566576aaaee5df 85 Pfam PF09827 CRISPR associated protein Cas2 1 67 1.0E-22 T 23-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 A3L01_02270 848b1ba02d797be5e1566576aaaee5df 85 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 71 5.6E-14 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 A3L01_02270 848b1ba02d797be5e1566576aaaee5df 85 Gene3D G3DSA:3.30.70.240 1 66 2.5E-31 T 23-10-2018 A3L01_04740 fec344c79315115467974a3f041ce6f8 229 PIRSF PIRSF005785 1 148 2.2E-7 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 A3L01_04740 fec344c79315115467974a3f041ce6f8 229 PIRSF PIRSF005785 151 225 3.1E-24 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 A3L01_04740 fec344c79315115467974a3f041ce6f8 229 SUPERFAMILY SSF55486 166 214 3.67E-9 T 23-10-2018 A3L01_04740 fec344c79315115467974a3f041ce6f8 229 Pfam PF07998 Peptidase family M54 160 218 2.9E-21 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 A3L01_04740 fec344c79315115467974a3f041ce6f8 229 Pfam PF07998 Peptidase family M54 1 138 9.4E-18 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 A3L01_04740 fec344c79315115467974a3f041ce6f8 229 Gene3D G3DSA:3.40.390.10 74 223 1.4E-19 T 23-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 A3L01_00895 a2ca4ee2ac8bd0459db6c269125cf940 342 Pfam PF01137 RNA 3'-terminal phosphate cyclase 8 324 3.6E-77 T 23-10-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain A3L01_00895 a2ca4ee2ac8bd0459db6c269125cf940 342 SUPERFAMILY SSF55205 1 214 1.9E-66 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A3L01_00895 a2ca4ee2ac8bd0459db6c269125cf940 342 SUPERFAMILY SSF52913 181 274 3.27E-23 T 23-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily A3L01_00895 a2ca4ee2ac8bd0459db6c269125cf940 342 Gene3D G3DSA:3.30.360.20 180 274 8.6E-127 T 23-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily A3L01_00895 a2ca4ee2ac8bd0459db6c269125cf940 342 ProSitePatterns PS01287 RNA 3'-terminal phosphate cyclase signature. 152 162 - T 23-10-2018 IPR020719 RNA 3'-terminal phosphate cyclase-like, conserved site A3L01_00895 a2ca4ee2ac8bd0459db6c269125cf940 342 PIRSF PIRSF005378 1 341 9.9E-110 T 23-10-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 A3L01_00895 a2ca4ee2ac8bd0459db6c269125cf940 342 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 182 273 2.9E-23 T 23-10-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain A3L01_00895 a2ca4ee2ac8bd0459db6c269125cf940 342 Gene3D G3DSA:3.65.10.20 4 319 8.6E-127 T 23-10-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily A3L01_00895 a2ca4ee2ac8bd0459db6c269125cf940 342 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 1 336 40.062 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 A3L01_00895 a2ca4ee2ac8bd0459db6c269125cf940 342 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 2 323 2.0E-128 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 A3L01_05265 a6bcf013fe73677db6afb2f69b5b1a1a 162 ProSitePatterns PS01318 TsaA-like domain signature. 81 92 - T 23-10-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site A3L01_05265 a6bcf013fe73677db6afb2f69b5b1a1a 162 SUPERFAMILY SSF118196 1 151 2.62E-55 T 23-10-2018 IPR036413 YaeB-like superfamily A3L01_05265 a6bcf013fe73677db6afb2f69b5b1a1a 162 Pfam PF01980 Uncharacterised protein family UPF0066 21 133 4.4E-41 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain A3L01_05265 a6bcf013fe73677db6afb2f69b5b1a1a 162 Gene3D G3DSA:2.40.30.70 5 149 6.0E-50 T 23-10-2018 IPR036414 YaeB, N-terminal domain superfamily A3L01_05265 a6bcf013fe73677db6afb2f69b5b1a1a 162 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 4 134 5.6E-43 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain A3L01_02635 f4c2266810d9c44bf9b7141d5e07dda1 322 Gene3D G3DSA:3.30.230.10 17 154 2.4E-10 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L01_02635 f4c2266810d9c44bf9b7141d5e07dda1 322 PIRSF PIRSF004884 1 309 1.4E-99 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 A3L01_02635 f4c2266810d9c44bf9b7141d5e07dda1 322 Gene3D G3DSA:3.30.70.890 155 265 2.4E-10 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A3L01_02635 f4c2266810d9c44bf9b7141d5e07dda1 322 Pfam PF00288 GHMP kinases N terminal domain 76 136 8.3E-7 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A3L01_02635 f4c2266810d9c44bf9b7141d5e07dda1 322 SUPERFAMILY SSF54211 1 146 8.35E-18 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L01_02635 f4c2266810d9c44bf9b7141d5e07dda1 322 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 1 307 1.5E-48 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 A3L01_01475 1ee1ffabc54f3b33f679f31e802c15b1 151 Pfam PF01877 RNA binding 9 131 1.9E-38 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 A3L01_01475 1ee1ffabc54f3b33f679f31e802c15b1 151 Gene3D G3DSA:3.30.1440.10 3 149 1.0E-45 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01475 1ee1ffabc54f3b33f679f31e802c15b1 151 SUPERFAMILY SSF55282 7 149 6.77E-41 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_03345 57392a236778a8e28fefe7b2ede1d0eb 200 ProSitePatterns PS01191 Ribosomal protein S3Ae signature. 47 59 - T 23-10-2018 IPR018281 Ribosomal protein S3Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_03345 57392a236778a8e28fefe7b2ede1d0eb 200 SMART SM01397 8 198 3.2E-101 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_03345 57392a236778a8e28fefe7b2ede1d0eb 200 Pfam PF01015 Ribosomal S3Ae family 11 198 1.7E-66 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_03345 57392a236778a8e28fefe7b2ede1d0eb 200 Hamap MF_00359 30S ribosomal protein S3Ae [rps3ae]. 8 198 36.447 T 23-10-2018 IPR030838 30S ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 A3L01_02190 1baaf7ad9d5056e93b15aba90c2fd337 373 PRINTS PR00423 Cell division protein FtsZ signature 156 177 7.8E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L01_02190 1baaf7ad9d5056e93b15aba90c2fd337 373 PRINTS PR00423 Cell division protein FtsZ signature 218 240 7.8E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L01_02190 1baaf7ad9d5056e93b15aba90c2fd337 373 PRINTS PR00423 Cell division protein FtsZ signature 128 148 7.8E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L01_02190 1baaf7ad9d5056e93b15aba90c2fd337 373 PRINTS PR00423 Cell division protein FtsZ signature 241 262 7.8E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L01_02190 1baaf7ad9d5056e93b15aba90c2fd337 373 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 43 203 4.8E-46 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L01_02190 1baaf7ad9d5056e93b15aba90c2fd337 373 Pfam PF12327 FtsZ family, C-terminal domain 251 343 6.8E-32 T 23-10-2018 IPR024757 Cell division protein FtsZ, C-terminal A3L01_02190 1baaf7ad9d5056e93b15aba90c2fd337 373 Gene3D G3DSA:3.40.50.1440 35 249 7.7E-83 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L01_02190 1baaf7ad9d5056e93b15aba90c2fd337 373 SMART SM00865 236 352 1.2E-49 T 23-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 A3L01_02190 1baaf7ad9d5056e93b15aba90c2fd337 373 SUPERFAMILY SSF52490 37 235 8.63E-70 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L01_02190 1baaf7ad9d5056e93b15aba90c2fd337 373 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 32 355 1.4E-135 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A3L01_02190 1baaf7ad9d5056e93b15aba90c2fd337 373 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 39 373 38.233 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A3L01_02190 1baaf7ad9d5056e93b15aba90c2fd337 373 ProSitePatterns PS01134 FtsZ protein signature 1. 74 108 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A3L01_02190 1baaf7ad9d5056e93b15aba90c2fd337 373 SMART SM00864 43 234 1.8E-106 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L01_02190 1baaf7ad9d5056e93b15aba90c2fd337 373 Gene3D G3DSA:3.30.1330.20 254 364 2.9E-35 T 23-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 A3L01_02190 1baaf7ad9d5056e93b15aba90c2fd337 373 SUPERFAMILY SSF55307 236 348 2.29E-38 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A3L01_02190 1baaf7ad9d5056e93b15aba90c2fd337 373 ProSitePatterns PS01135 FtsZ protein signature 2. 127 148 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A3L01_08650 2f39b1cf129f418b8bf1512847f821ac 370 Pfam PF10102 Domain of unknown function (DUF2341) 86 155 5.4E-6 T 23-10-2018 IPR018765 Domain of unknown function DUF2341 A3L01_03430 5d5f480a615123dc63ecb8d586166e78 368 SUPERFAMILY SSF54862 230 329 5.44E-11 T 23-10-2018 A3L01_03430 5d5f480a615123dc63ecb8d586166e78 368 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 233 244 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_03430 5d5f480a615123dc63ecb8d586166e78 368 Pfam PF17179 4Fe-4S dicluster domain 233 326 7.5E-28 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_03430 5d5f480a615123dc63ecb8d586166e78 368 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 312 323 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_06115 7bf447e9576fb04866149b7a29f25e65 143 Gene3D G3DSA:3.40.50.280 1 143 1.9E-56 T 23-10-2018 A3L01_06115 7bf447e9576fb04866149b7a29f25e65 143 Pfam PF02310 B12 binding domain 8 120 6.1E-25 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A3L01_06115 7bf447e9576fb04866149b7a29f25e65 143 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 6 138 2.7E-59 T 23-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L01_06115 7bf447e9576fb04866149b7a29f25e65 143 SUPERFAMILY SSF52242 5 133 2.49E-48 T 23-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 A3L01_06780 b9ceb951b77d720d65f1ee0d22e8c401 198 Gene3D G3DSA:1.10.10.10 4 105 7.7E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_06780 b9ceb951b77d720d65f1ee0d22e8c401 198 Pfam PF01022 Bacterial regulatory protein, arsR family 16 61 4.0E-13 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_06780 b9ceb951b77d720d65f1ee0d22e8c401 198 SUPERFAMILY SSF46785 6 174 2.02E-28 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_06780 b9ceb951b77d720d65f1ee0d22e8c401 198 SMART SM00418 9 89 2.0E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_08190 b0b4358140f06a71d5a87cfc925943e4 396 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 266 369 1.2E-33 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A3L01_08190 b0b4358140f06a71d5a87cfc925943e4 396 SUPERFAMILY SSF52518 8 254 7.85E-70 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L01_08190 b0b4358140f06a71d5a87cfc925943e4 396 Gene3D G3DSA:3.40.50.970 7 255 6.8E-99 T 23-10-2018 A3L01_08190 b0b4358140f06a71d5a87cfc925943e4 396 Gene3D G3DSA:3.40.50.920 256 396 9.7E-45 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L01_08190 b0b4358140f06a71d5a87cfc925943e4 396 SUPERFAMILY SSF52922 257 378 1.09E-35 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L01_08190 b0b4358140f06a71d5a87cfc925943e4 396 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 20 242 6.2E-79 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L01_05825 dadc52e00d3159d2dbbfa3102230f4b9 316 SUPERFAMILY SSF50998 115 281 5.1E-5 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A3L01_06085 3c1a36e38e984f8c22e9d657dbadae34 139 Pfam PF01909 Nucleotidyltransferase domain 12 57 5.7E-9 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L01_06085 3c1a36e38e984f8c22e9d657dbadae34 139 Gene3D G3DSA:3.30.460.10 4 106 4.0E-16 T 23-10-2018 A3L01_06085 3c1a36e38e984f8c22e9d657dbadae34 139 SUPERFAMILY SSF81301 11 115 6.35E-18 T 23-10-2018 A3L01_04040 0c059ffb919c617ee4a1af67e72eb32c 658 Gene3D G3DSA:3.40.50.300 2 192 1.3E-49 T 23-10-2018 A3L01_04040 0c059ffb919c617ee4a1af67e72eb32c 658 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 158 2.4E-12 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L01_04040 0c059ffb919c617ee4a1af67e72eb32c 658 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 53 68 5.8E-8 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_04040 0c059ffb919c617ee4a1af67e72eb32c 658 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 5.8E-8 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_04040 0c059ffb919c617ee4a1af67e72eb32c 658 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 5.8E-8 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_04040 0c059ffb919c617ee4a1af67e72eb32c 658 SUPERFAMILY SSF52540 5 177 3.03E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_04040 0c059ffb919c617ee4a1af67e72eb32c 658 Pfam PF02421 Ferrous iron transport protein B 4 159 9.9E-65 T 23-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 A3L01_04040 0c059ffb919c617ee4a1af67e72eb32c 658 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 9 625 9.1E-189 T 23-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 A3L01_04040 0c059ffb919c617ee4a1af67e72eb32c 658 Pfam PF07670 Nucleoside recognition 353 447 5.2E-13 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A3L01_04040 0c059ffb919c617ee4a1af67e72eb32c 658 Pfam PF07670 Nucleoside recognition 514 628 4.0E-27 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A3L01_04040 0c059ffb919c617ee4a1af67e72eb32c 658 Pfam PF07664 Ferrous iron transport protein B C terminus 457 509 2.9E-18 T 23-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 A3L01_03065 fa9837aac70be07710831987754a9854 240 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A3L01_03065 fa9837aac70be07710831987754a9854 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 236 7.4E-58 T 23-10-2018 A3L01_03065 fa9837aac70be07710831987754a9854 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 7.0E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_03065 fa9837aac70be07710831987754a9854 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 7.0E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_03065 fa9837aac70be07710831987754a9854 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 7.0E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_03065 fa9837aac70be07710831987754a9854 240 SUPERFAMILY SSF51735 5 239 1.07E-75 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_03065 fa9837aac70be07710831987754a9854 240 Gene3D G3DSA:3.40.50.720 1 237 6.5E-78 T 23-10-2018 A3L01_03065 fa9837aac70be07710831987754a9854 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 6.2E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_03065 fa9837aac70be07710831987754a9854 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 6.2E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_03065 fa9837aac70be07710831987754a9854 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.2E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_03065 fa9837aac70be07710831987754a9854 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 6.2E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_03065 fa9837aac70be07710831987754a9854 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 6.2E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_03065 fa9837aac70be07710831987754a9854 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 6.2E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_00860 2f791e075707d90650905b517f56b2c0 522 Gene3D G3DSA:3.90.226.10 1 260 3.7E-98 T 23-10-2018 A3L01_00860 2f791e075707d90650905b517f56b2c0 522 SUPERFAMILY SSF52096 255 522 6.28E-93 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L01_00860 2f791e075707d90650905b517f56b2c0 522 SUPERFAMILY SSF52096 3 257 1.66E-79 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L01_00860 2f791e075707d90650905b517f56b2c0 522 Pfam PF01039 Carboxyl transferase domain 28 520 6.7E-203 T 23-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A3L01_00860 2f791e075707d90650905b517f56b2c0 522 Gene3D G3DSA:3.90.226.10 262 522 7.0E-96 T 23-10-2018 A3L01_03255 a444c1ddb6fa5d457a52cf3b910c2b94 642 Pfam PF00750 tRNA synthetases class I (R) 105 360 6.4E-24 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 A3L01_03255 a444c1ddb6fa5d457a52cf3b910c2b94 642 Pfam PF00750 tRNA synthetases class I (R) 390 492 2.1E-10 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 A3L01_03255 a444c1ddb6fa5d457a52cf3b910c2b94 642 SMART SM01016 8 95 1.9E-22 T 23-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L01_03255 a444c1ddb6fa5d457a52cf3b910c2b94 642 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 135 144 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_03255 a444c1ddb6fa5d457a52cf3b910c2b94 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 330 351 1.8E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L01_03255 a444c1ddb6fa5d457a52cf3b910c2b94 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 125 140 1.8E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L01_03255 a444c1ddb6fa5d457a52cf3b910c2b94 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 164 177 1.8E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L01_03255 a444c1ddb6fa5d457a52cf3b910c2b94 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 140 156 1.8E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L01_03255 a444c1ddb6fa5d457a52cf3b910c2b94 642 SUPERFAMILY SSF55190 7 116 7.59E-19 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A3L01_03255 a444c1ddb6fa5d457a52cf3b910c2b94 642 Gene3D G3DSA:1.10.730.10 524 642 6.1E-43 T 23-10-2018 A3L01_03255 a444c1ddb6fa5d457a52cf3b910c2b94 642 SMART SM00836 520 642 7.5E-53 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A3L01_03255 a444c1ddb6fa5d457a52cf3b910c2b94 642 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 10 95 4.1E-14 T 23-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L01_03255 a444c1ddb6fa5d457a52cf3b910c2b94 642 Pfam PF05746 DALR anticodon binding domain 520 642 4.5E-38 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A3L01_03255 a444c1ddb6fa5d457a52cf3b910c2b94 642 Gene3D G3DSA:3.30.1360.70 6 121 8.9E-32 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A3L01_03255 a444c1ddb6fa5d457a52cf3b910c2b94 642 Hamap MF_00123 Arginine--tRNA ligase [argS]. 12 642 27.929 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L01_03255 a444c1ddb6fa5d457a52cf3b910c2b94 642 Gene3D G3DSA:3.40.50.620 122 523 3.0E-156 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_03255 a444c1ddb6fa5d457a52cf3b910c2b94 642 SUPERFAMILY SSF52374 121 513 8.8E-76 T 23-10-2018 A3L01_03255 a444c1ddb6fa5d457a52cf3b910c2b94 642 SUPERFAMILY SSF47323 516 642 1.44E-35 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_01610 415d63591cd6022d90e2ac05896d9f5f 1881 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 909 919 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A3L01_01610 415d63591cd6022d90e2ac05896d9f5f 1881 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 1425 1498 5.6E-7 T 23-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial A3L01_01610 415d63591cd6022d90e2ac05896d9f5f 1881 PRINTS PR00723 Subtilisin serine protease family (S8) signature 908 924 7.5E-12 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L01_01610 415d63591cd6022d90e2ac05896d9f5f 1881 PRINTS PR00723 Subtilisin serine protease family (S8) signature 253 272 7.5E-12 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L01_01610 415d63591cd6022d90e2ac05896d9f5f 1881 Gene3D G3DSA:2.60.40.10 1578 1682 4.5E-7 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_01610 415d63591cd6022d90e2ac05896d9f5f 1881 Pfam PF00082 Subtilase family 253 962 4.1E-26 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A3L01_01610 415d63591cd6022d90e2ac05896d9f5f 1881 Pfam PF07705 CARDB 1579 1667 1.3E-6 T 23-10-2018 IPR011635 CARDB domain A3L01_01610 415d63591cd6022d90e2ac05896d9f5f 1881 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 258 269 - T 23-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A3L01_01610 415d63591cd6022d90e2ac05896d9f5f 1881 SUPERFAMILY SSF52743 111 980 8.91E-46 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L01_01610 415d63591cd6022d90e2ac05896d9f5f 1881 Gene3D G3DSA:3.40.50.200 234 315 2.1E-6 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L01_01610 415d63591cd6022d90e2ac05896d9f5f 1881 Gene3D G3DSA:3.40.50.200 672 978 3.7E-43 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L01_01610 415d63591cd6022d90e2ac05896d9f5f 1881 Gene3D G3DSA:2.60.120.380 1414 1517 2.4E-12 T 23-10-2018 A3L01_01410 a634421f0a3119fd18e53eeb025caec5 372 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 13 352 6.6E-132 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A3L01_01410 a634421f0a3119fd18e53eeb025caec5 372 Pfam PF01070 FMN-dependent dehydrogenase 15 105 1.4E-8 T 23-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 A3L01_01410 a634421f0a3119fd18e53eeb025caec5 372 Pfam PF01070 FMN-dependent dehydrogenase 186 346 8.7E-16 T 23-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 A3L01_01410 a634421f0a3119fd18e53eeb025caec5 372 SUPERFAMILY SSF51395 32 367 5.76E-80 T 23-10-2018 A3L01_01410 a634421f0a3119fd18e53eeb025caec5 372 Gene3D G3DSA:3.20.20.70 10 372 3.8E-129 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_01410 a634421f0a3119fd18e53eeb025caec5 372 PIRSF PIRSF003314 7 363 1.3E-133 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A3L01_01410 a634421f0a3119fd18e53eeb025caec5 372 SMART SM01240 30 364 3.5E-4 T 23-10-2018 A3L01_01410 a634421f0a3119fd18e53eeb025caec5 372 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 10 353 41.143 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A3L01_02410 e9ccc4fcb0d1f39d7bdee4909f443e26 680 Pfam PF05753 Translocon-associated protein beta (TRAPB) 332 445 1.9E-7 T 23-10-2018 A3L01_08400 41291435c41e8605c15ab6b2395f5849 211 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 125 139 - T 23-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A3L01_08400 41291435c41e8605c15ab6b2395f5849 211 Gene3D G3DSA:3.40.50.150 12 193 1.8E-34 T 23-10-2018 A3L01_08400 41291435c41e8605c15ab6b2395f5849 211 SUPERFAMILY SSF53335 5 199 7.54E-37 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_08400 41291435c41e8605c15ab6b2395f5849 211 Pfam PF08241 Methyltransferase domain 41 135 9.3E-24 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A3L01_05600 38db2322857ef93b8669370152643b39 169 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 23 165 3.4E-62 T 23-10-2018 IPR002790 Conserved hypothetical protein CHP00288 A3L01_05600 38db2322857ef93b8669370152643b39 169 Pfam PF01936 NYN domain 32 163 1.1E-18 T 23-10-2018 IPR021139 NYN domain, limkain-b1-type A3L01_05600 38db2322857ef93b8669370152643b39 169 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 33 105 2.0E-29 T 23-10-2018 A3L01_05600 38db2322857ef93b8669370152643b39 169 Gene3D G3DSA:3.40.50.1010 24 165 3.9E-9 T 23-10-2018 A3L01_04835 909a2a1f8b8af872746be96f8112a18e 191 Pfam PF01569 PAP2 superfamily 84 176 9.0E-10 T 23-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A3L01_04835 909a2a1f8b8af872746be96f8112a18e 191 Gene3D G3DSA:1.20.144.10 10 112 2.5E-5 T 23-10-2018 A3L01_04835 909a2a1f8b8af872746be96f8112a18e 191 Gene3D G3DSA:1.20.144.10 114 189 2.4E-10 T 23-10-2018 A3L01_04835 909a2a1f8b8af872746be96f8112a18e 191 SUPERFAMILY SSF48317 30 185 1.09E-25 T 23-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily A3L01_04835 909a2a1f8b8af872746be96f8112a18e 191 SMART SM00014 82 183 0.0053 T 23-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A3L01_06765 2db07ec4b3fb9ccdfeb9d316540542f2 308 PIRSF PIRSF016202 6 307 7.5E-96 T 23-10-2018 IPR007184 Mannoside phosphorylase A3L01_06765 2db07ec4b3fb9ccdfeb9d316540542f2 308 Pfam PF04041 beta-1,4-mannooligosaccharide phosphorylase 31 301 3.1E-75 T 23-10-2018 IPR007184 Mannoside phosphorylase A3L01_06765 2db07ec4b3fb9ccdfeb9d316540542f2 308 SUPERFAMILY SSF75005 25 301 5.05E-66 T 23-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A3L01_06765 2db07ec4b3fb9ccdfeb9d316540542f2 308 Gene3D G3DSA:2.115.10.20 4 301 9.4E-96 T 23-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A3L01_00755 9646bf528631bad6dee2c7315c782e88 635 Gene3D G3DSA:3.40.50.970 6 198 1.7E-55 T 23-10-2018 A3L01_00755 9646bf528631bad6dee2c7315c782e88 635 Gene3D G3DSA:3.30.70.20 572 635 1.9E-11 T 23-10-2018 A3L01_00755 9646bf528631bad6dee2c7315c782e88 635 Gene3D G3DSA:3.40.50.970 410 571 1.1E-23 T 23-10-2018 A3L01_00755 9646bf528631bad6dee2c7315c782e88 635 PIRSF PIRSF006439 10 632 1.3E-218 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A3L01_00755 9646bf528631bad6dee2c7315c782e88 635 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 610 621 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_00755 9646bf528631bad6dee2c7315c782e88 635 SUPERFAMILY SSF52922 245 328 1.21E-7 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L01_00755 9646bf528631bad6dee2c7315c782e88 635 SUPERFAMILY SSF54862 563 628 7.65E-14 T 23-10-2018 A3L01_00755 9646bf528631bad6dee2c7315c782e88 635 Pfam PF00037 4Fe-4S binding domain 604 626 2.6E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_00755 9646bf528631bad6dee2c7315c782e88 635 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 412 553 1.1E-31 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L01_00755 9646bf528631bad6dee2c7315c782e88 635 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 21 625 5.0E-219 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A3L01_00755 9646bf528631bad6dee2c7315c782e88 635 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 33 214 3.1E-15 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L01_00755 9646bf528631bad6dee2c7315c782e88 635 SUPERFAMILY SSF52518 375 560 2.16E-37 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L01_00755 9646bf528631bad6dee2c7315c782e88 635 SUPERFAMILY SSF52518 20 254 4.55E-58 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L01_05165 ee4325cd0f4fdb590bb32e23746313ba 601 Gene3D G3DSA:3.20.20.70 1 457 6.1E-166 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_05165 ee4325cd0f4fdb590bb32e23746313ba 601 SUPERFAMILY SSF89000 297 448 2.04E-53 T 23-10-2018 A3L01_05165 ee4325cd0f4fdb590bb32e23746313ba 601 SUPERFAMILY SSF51230 524 601 8.25E-26 T 23-10-2018 IPR011053 Single hybrid motif A3L01_05165 ee4325cd0f4fdb590bb32e23746313ba 601 Pfam PF00682 HMGL-like 3 234 3.5E-40 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A3L01_05165 ee4325cd0f4fdb590bb32e23746313ba 601 Pfam PF02436 Conserved carboxylase domain 292 474 1.2E-56 T 23-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 A3L01_05165 ee4325cd0f4fdb590bb32e23746313ba 601 SUPERFAMILY SSF51569 2 301 4.76E-86 T 23-10-2018 A3L01_05165 ee4325cd0f4fdb590bb32e23746313ba 601 Gene3D G3DSA:2.40.50.100 527 601 2.4E-29 T 23-10-2018 A3L01_05165 ee4325cd0f4fdb590bb32e23746313ba 601 Pfam PF00364 Biotin-requiring enzyme 535 600 6.0E-24 T 23-10-2018 IPR000089 Biotin/lipoyl attachment A3L01_05165 ee4325cd0f4fdb590bb32e23746313ba 601 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 557 574 - T 23-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A3L01_00270 73ab5b42ef08e9641927696de9970521 172 Pfam PF06510 Protein of unknown function (DUF1102) 48 171 3.1E-35 T 23-10-2018 IPR009482 Protein of unknown function DUF1102 A3L01_09470 1cfcac24b67dbd79ed15cfa089598bf0 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 324 2.9E-45 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_09470 1cfcac24b67dbd79ed15cfa089598bf0 330 SUPERFAMILY SSF161098 96 307 2.81E-7 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_09470 1cfcac24b67dbd79ed15cfa089598bf0 330 Gene3D G3DSA:1.10.3720.10 93 319 1.4E-9 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_07430 53d462a7ef39db65558105e0d3036e24 439 Gene3D G3DSA:3.50.50.60 107 431 2.8E-147 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_07430 53d462a7ef39db65558105e0d3036e24 439 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 282 1.1E-68 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L01_07430 53d462a7ef39db65558105e0d3036e24 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 1.8E-17 T 23-10-2018 A3L01_07430 53d462a7ef39db65558105e0d3036e24 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 1.8E-17 T 23-10-2018 A3L01_07430 53d462a7ef39db65558105e0d3036e24 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 1.8E-17 T 23-10-2018 A3L01_07430 53d462a7ef39db65558105e0d3036e24 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 170 1.8E-17 T 23-10-2018 A3L01_07430 53d462a7ef39db65558105e0d3036e24 439 SUPERFAMILY SSF51905 142 307 4.36E-35 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_07430 53d462a7ef39db65558105e0d3036e24 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 9.6E-23 T 23-10-2018 A3L01_07430 53d462a7ef39db65558105e0d3036e24 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 9.6E-23 T 23-10-2018 A3L01_07430 53d462a7ef39db65558105e0d3036e24 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 9.6E-23 T 23-10-2018 A3L01_07430 53d462a7ef39db65558105e0d3036e24 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 9.6E-23 T 23-10-2018 A3L01_07430 53d462a7ef39db65558105e0d3036e24 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 9.6E-23 T 23-10-2018 A3L01_07430 53d462a7ef39db65558105e0d3036e24 439 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 324 424 2.6E-16 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A3L01_07430 53d462a7ef39db65558105e0d3036e24 439 Gene3D G3DSA:3.50.50.60 2 331 2.8E-147 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_07430 53d462a7ef39db65558105e0d3036e24 439 SUPERFAMILY SSF51905 1 191 1.07E-47 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_07430 53d462a7ef39db65558105e0d3036e24 439 SUPERFAMILY SSF55424 316 436 9.62E-27 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A3L01_09055 ffd1919ff51a129fec385c1b7cf78611 702 SUPERFAMILY SSF56300 436 663 7.42E-20 T 23-10-2018 A3L01_09055 ffd1919ff51a129fec385c1b7cf78611 702 Pfam PF04042 DNA polymerase alpha/epsilon subunit B 436 640 1.5E-14 T 23-10-2018 IPR007185 DNA polymerase alpha/epsilon, subunit B GO:0003677|GO:0003887|GO:0006260 A3L01_09055 ffd1919ff51a129fec385c1b7cf78611 702 Gene3D G3DSA:3.60.21.50 419 675 9.0E-25 T 23-10-2018 A3L01_09055 ffd1919ff51a129fec385c1b7cf78611 702 Hamap MF_00325 DNA polymerase II small subunit [polB]. 2 692 32.633 T 23-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L01_09055 ffd1919ff51a129fec385c1b7cf78611 702 PIRSF PIRSF000803 29 699 3.6E-179 T 23-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L01_09055 ffd1919ff51a129fec385c1b7cf78611 702 Gene3D G3DSA:1.10.8.800 2 68 2.2E-22 T 23-10-2018 A3L01_09055 ffd1919ff51a129fec385c1b7cf78611 702 Gene3D G3DSA:2.40.50.140 340 413 4.6E-5 T 23-10-2018 A3L01_05675 58f25e5aef6d16b9785083f67b4a85cc 873 SMART SM00490 453 538 1.2E-19 T 23-10-2018 IPR001650 Helicase, C-terminal A3L01_05675 58f25e5aef6d16b9785083f67b4a85cc 873 Gene3D G3DSA:3.40.50.300 404 600 1.4E-28 T 23-10-2018 A3L01_05675 58f25e5aef6d16b9785083f67b4a85cc 873 SUPERFAMILY SSF52540 227 552 1.08E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_05675 58f25e5aef6d16b9785083f67b4a85cc 873 Pfam PF00270 DEAD/DEAH box helicase 219 382 3.7E-24 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L01_05675 58f25e5aef6d16b9785083f67b4a85cc 873 Gene3D G3DSA:3.40.50.300 200 402 1.2E-50 T 23-10-2018 A3L01_05675 58f25e5aef6d16b9785083f67b4a85cc 873 SMART SM00487 213 410 2.0E-29 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L01_05675 58f25e5aef6d16b9785083f67b4a85cc 873 Pfam PF00271 Helicase conserved C-terminal domain 435 536 5.8E-13 T 23-10-2018 IPR001650 Helicase, C-terminal A3L01_09445 f21ea625f3242069b9a48493defb7fd1 266 Gene3D G3DSA:3.40.50.10320 1 266 1.0E-98 T 23-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A3L01_09445 f21ea625f3242069b9a48493defb7fd1 266 SUPERFAMILY SSF102588 32 255 4.84E-58 T 23-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A3L01_09445 f21ea625f3242069b9a48493defb7fd1 266 Pfam PF02585 GlcNAc-PI de-N-acetylase 34 160 3.7E-29 T 23-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A3L01_02575 cc1a41789fdc220747deb63f391cfa16 225 SUPERFAMILY SSF159612 3 218 5.62E-111 T 23-10-2018 A3L01_02575 cc1a41789fdc220747deb63f391cfa16 225 Pfam PF15517 TBP-interacting protein N-terminus 3 102 2.9E-44 T 23-10-2018 IPR029125 TBP-interacting protein, N-terminal A3L01_02575 cc1a41789fdc220747deb63f391cfa16 225 Gene3D G3DSA:3.90.79.30 101 220 8.0E-63 T 23-10-2018 A3L01_02575 cc1a41789fdc220747deb63f391cfa16 225 Gene3D G3DSA:3.40.1350.70 1 100 3.3E-47 T 23-10-2018 IPR038230 TBP-interacting protein, N-terminal superfamily A3L01_05695 f610ed916f76129e01774122448b39e5 479 SUPERFAMILY SSF53850 82 326 1.39E-38 T 23-10-2018 A3L01_05695 f610ed916f76129e01774122448b39e5 479 Gene3D G3DSA:3.40.190.10 84 314 7.3E-35 T 23-10-2018 A3L01_05695 f610ed916f76129e01774122448b39e5 479 Gene3D G3DSA:3.40.190.10 149 268 7.3E-35 T 23-10-2018 A3L01_05695 f610ed916f76129e01774122448b39e5 479 Pfam PF13343 Bacterial extracellular solute-binding protein 85 302 1.7E-18 T 23-10-2018 A3L01_07935 24e5ba3edc7f93ce29524c781a72ea10 474 SUPERFAMILY SSF48208 230 461 3.16E-9 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A3L01_07935 24e5ba3edc7f93ce29524c781a72ea10 474 Pfam PF06662 D-glucuronyl C5-epimerase C-terminus 284 450 5.0E-40 T 23-10-2018 IPR010598 D-glucuronyl C5-epimerase, C-terminal KEGG: 00534+5.1.3.17|MetaCyc: PWY-6558|Reactome: R-HSA-2022928 A3L01_05080 b93141aaf7243fd6959c7779d3378348 296 Gene3D G3DSA:3.30.930.10 15 254 1.1E-35 T 23-10-2018 A3L01_05080 b93141aaf7243fd6959c7779d3378348 296 Pfam PF13393 Histidyl-tRNA synthetase 5 177 4.0E-16 T 23-10-2018 A3L01_05080 b93141aaf7243fd6959c7779d3378348 296 Pfam PF13393 Histidyl-tRNA synthetase 191 256 2.3E-8 T 23-10-2018 A3L01_05080 b93141aaf7243fd6959c7779d3378348 296 SUPERFAMILY SSF55681 13 255 4.97E-30 T 23-10-2018 A3L01_05930 c50abfe5044885df30b8d9f1c16f0234 412 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 23-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A3L01_05930 c50abfe5044885df30b8d9f1c16f0234 412 SUPERFAMILY SSF52540 71 354 2.62E-74 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_05930 c50abfe5044885df30b8d9f1c16f0234 412 Gene3D G3DSA:3.40.50.300 1 207 2.0E-75 T 23-10-2018 A3L01_05930 c50abfe5044885df30b8d9f1c16f0234 412 Gene3D G3DSA:3.40.50.300 212 407 1.7E-51 T 23-10-2018 A3L01_05930 c50abfe5044885df30b8d9f1c16f0234 412 Pfam PF00271 Helicase conserved C-terminal domain 242 333 1.4E-25 T 23-10-2018 IPR001650 Helicase, C-terminal A3L01_05930 c50abfe5044885df30b8d9f1c16f0234 412 SMART SM00490 252 333 2.9E-32 T 23-10-2018 IPR001650 Helicase, C-terminal A3L01_05930 c50abfe5044885df30b8d9f1c16f0234 412 SMART SM00487 20 223 4.2E-63 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L01_05930 c50abfe5044885df30b8d9f1c16f0234 412 Pfam PF00270 DEAD/DEAH box helicase 25 191 9.6E-48 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L01_02770 ff7c53885f903d4807396a46a3412e07 348 PIRSF PIRSF004869 1 313 9.9E-97 T 23-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted A3L01_02770 ff7c53885f903d4807396a46a3412e07 348 Gene3D G3DSA:3.20.20.70 63 286 6.0E-36 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_02770 ff7c53885f903d4807396a46a3412e07 348 Pfam PF04055 Radical SAM superfamily 78 234 2.6E-21 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L01_02770 ff7c53885f903d4807396a46a3412e07 348 Pfam PF13353 4Fe-4S single cluster domain 73 166 3.9E-7 T 23-10-2018 A3L01_02770 ff7c53885f903d4807396a46a3412e07 348 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 6 345 6.0E-112 T 23-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme A3L01_02770 ff7c53885f903d4807396a46a3412e07 348 SUPERFAMILY SSF102114 56 315 1.57E-34 T 23-10-2018 A3L01_04970 47ee1f4a33d83a6f97a7cc756e836c07 361 Gene3D G3DSA:3.50.50.60 4 277 5.1E-98 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_04970 47ee1f4a33d83a6f97a7cc756e836c07 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 1.0E-22 T 23-10-2018 A3L01_04970 47ee1f4a33d83a6f97a7cc756e836c07 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 262 1.0E-22 T 23-10-2018 A3L01_04970 47ee1f4a33d83a6f97a7cc756e836c07 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 94 112 1.0E-22 T 23-10-2018 A3L01_04970 47ee1f4a33d83a6f97a7cc756e836c07 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.0E-22 T 23-10-2018 A3L01_04970 47ee1f4a33d83a6f97a7cc756e836c07 361 Gene3D G3DSA:3.30.390.30 299 357 1.8E-16 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A3L01_04970 47ee1f4a33d83a6f97a7cc756e836c07 361 SUPERFAMILY SSF51905 2 172 2.19E-40 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_04970 47ee1f4a33d83a6f97a7cc756e836c07 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 2 24 3.0E-9 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L01_04970 47ee1f4a33d83a6f97a7cc756e836c07 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 95 103 3.0E-9 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L01_04970 47ee1f4a33d83a6f97a7cc756e836c07 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 133 157 3.0E-9 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L01_04970 47ee1f4a33d83a6f97a7cc756e836c07 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 250 268 3.0E-9 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L01_04970 47ee1f4a33d83a6f97a7cc756e836c07 361 Gene3D G3DSA:3.50.50.60 106 223 5.1E-98 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_04970 47ee1f4a33d83a6f97a7cc756e836c07 361 SUPERFAMILY SSF55424 291 351 1.95E-17 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A3L01_04970 47ee1f4a33d83a6f97a7cc756e836c07 361 SUPERFAMILY SSF51905 114 288 1.59E-26 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_04970 47ee1f4a33d83a6f97a7cc756e836c07 361 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 279 1.2E-53 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L01_07000 ad0025c9cff57050f3b552a100a1965d 726 SUPERFAMILY SSF158702 493 701 4.18E-59 T 23-10-2018 A3L01_07000 ad0025c9cff57050f3b552a100a1965d 726 Hamap MF_00442 ATP-dependent DNA helicase Hel308 [hel308]. 9 700 30.603 T 23-10-2018 IPR022965 ATP-dependent DNA helicase Hel308 GO:0004386 A3L01_07000 ad0025c9cff57050f3b552a100a1965d 726 Gene3D G3DSA:3.40.50.300 8 200 9.6E-73 T 23-10-2018 A3L01_07000 ad0025c9cff57050f3b552a100a1965d 726 Gene3D G3DSA:1.10.150.20 643 699 2.5E-22 T 23-10-2018 A3L01_07000 ad0025c9cff57050f3b552a100a1965d 726 SUPERFAMILY SSF46785 405 492 1.9E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_07000 ad0025c9cff57050f3b552a100a1965d 726 Gene3D G3DSA:3.40.50.300 201 399 3.0E-62 T 23-10-2018 A3L01_07000 ad0025c9cff57050f3b552a100a1965d 726 Pfam PF14520 Helix-hairpin-helix domain 646 692 3.7E-9 T 23-10-2018 A3L01_07000 ad0025c9cff57050f3b552a100a1965d 726 SMART SM00487 20 204 3.5E-31 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L01_07000 ad0025c9cff57050f3b552a100a1965d 726 Pfam PF00271 Helicase conserved C-terminal domain 233 373 6.3E-11 T 23-10-2018 IPR001650 Helicase, C-terminal A3L01_07000 ad0025c9cff57050f3b552a100a1965d 726 Gene3D G3DSA:1.10.3380.30 411 641 7.0E-73 T 23-10-2018 A3L01_07000 ad0025c9cff57050f3b552a100a1965d 726 Pfam PF00270 DEAD/DEAH box helicase 26 180 1.8E-24 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L01_07000 ad0025c9cff57050f3b552a100a1965d 726 SUPERFAMILY SSF52540 36 387 4.31E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_07000 ad0025c9cff57050f3b552a100a1965d 726 SMART SM00278 678 697 0.96 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L01_07000 ad0025c9cff57050f3b552a100a1965d 726 SMART SM00278 645 664 0.59 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L01_07000 ad0025c9cff57050f3b552a100a1965d 726 SMART SM00490 288 374 1.3E-15 T 23-10-2018 IPR001650 Helicase, C-terminal A3L01_01230 8d6c6b2e7afeb3d966562fdbb36acce4 142 PIRSF PIRSF002181 1 142 1.6E-42 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A3L01_01230 8d6c6b2e7afeb3d966562fdbb36acce4 142 Pfam PF00572 Ribosomal protein L13 3 103 2.2E-11 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A3L01_01230 8d6c6b2e7afeb3d966562fdbb36acce4 142 SUPERFAMILY SSF52161 2 142 3.92E-43 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 A3L01_01230 8d6c6b2e7afeb3d966562fdbb36acce4 142 Gene3D G3DSA:3.90.1180.10 1 142 8.0E-57 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 A3L01_01230 8d6c6b2e7afeb3d966562fdbb36acce4 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 1 132 20.325 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A3L01_01230 8d6c6b2e7afeb3d966562fdbb36acce4 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 79 102 - T 23-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 A3L01_01230 8d6c6b2e7afeb3d966562fdbb36acce4 142 TIGRFAM TIGR01077 L13_A_E: ribosomal protein uL13 3 142 1.4E-63 T 23-10-2018 IPR005755 Ribosomal protein L13, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 A3L01_03360 48921df926c00ee2fe8df34c46ee1dce 149 SUPERFAMILY SSF46785 5 65 1.42E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_03360 48921df926c00ee2fe8df34c46ee1dce 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 4.7E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_03360 48921df926c00ee2fe8df34c46ee1dce 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 4.7E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_03360 48921df926c00ee2fe8df34c46ee1dce 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 4.7E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_03360 48921df926c00ee2fe8df34c46ee1dce 149 Gene3D G3DSA:1.10.10.10 1 56 2.4E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_03360 48921df926c00ee2fe8df34c46ee1dce 149 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 52 1.4E-15 T 23-10-2018 A3L01_03360 48921df926c00ee2fe8df34c46ee1dce 149 SMART SM00344 5 111 1.7E-19 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L01_03360 48921df926c00ee2fe8df34c46ee1dce 149 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 36 51 7.7E-5 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L01_03360 48921df926c00ee2fe8df34c46ee1dce 149 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 20 36 7.7E-5 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L01_03360 48921df926c00ee2fe8df34c46ee1dce 149 Gene3D G3DSA:3.30.70.920 57 149 7.0E-28 T 23-10-2018 A3L01_03360 48921df926c00ee2fe8df34c46ee1dce 149 SUPERFAMILY SSF54909 66 146 5.01E-6 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L01_06430 0f06e387a7197cc09438962be62b3653 109 Pfam PF01588 Putative tRNA binding domain 14 107 3.4E-24 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A3L01_06430 0f06e387a7197cc09438962be62b3653 109 Gene3D G3DSA:2.40.50.140 2 109 4.1E-33 T 23-10-2018 A3L01_06430 0f06e387a7197cc09438962be62b3653 109 SUPERFAMILY SSF50249 5 108 7.1E-28 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_03545 bde69f072f01e083de86e27f7d5efc98 389 Pfam PF00155 Aminotransferase class I and II 28 378 6.4E-77 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L01_03545 bde69f072f01e083de86e27f7d5efc98 389 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A3L01_03545 bde69f072f01e083de86e27f7d5efc98 389 Gene3D G3DSA:3.40.640.10 58 280 2.5E-151 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L01_03545 bde69f072f01e083de86e27f7d5efc98 389 Gene3D G3DSA:3.90.1150.10 29 378 2.5E-151 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L01_03545 bde69f072f01e083de86e27f7d5efc98 389 SUPERFAMILY SSF53383 2 385 4.03E-124 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L01_04125 42efaba5cd90469c9fc9a4ffa2dd5b50 441 Pfam PF01523 Putative modulator of DNA gyrase 14 304 1.1E-45 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L01_04125 42efaba5cd90469c9fc9a4ffa2dd5b50 441 Gene3D G3DSA:3.30.2290.10 1 206 2.8E-20 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L01_04125 42efaba5cd90469c9fc9a4ffa2dd5b50 441 SUPERFAMILY SSF111283 2 439 2.49E-97 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L01_02280 fb0ab80d23bc44eeb5a16cb6667b056e 250 Gene3D G3DSA:3.30.70.1890 1 121 4.4E-12 T 23-10-2018 A3L01_02280 fb0ab80d23bc44eeb5a16cb6667b056e 250 PIRSF PIRSF005054 1 250 1.2E-53 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L01_02280 fb0ab80d23bc44eeb5a16cb6667b056e 250 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 42 248 1.6E-25 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L01_02280 fb0ab80d23bc44eeb5a16cb6667b056e 250 Pfam PF01881 CRISPR associated protein Cas6 100 249 2.6E-22 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L01_02280 fb0ab80d23bc44eeb5a16cb6667b056e 250 Gene3D G3DSA:3.30.70.1900 123 250 4.2E-22 T 23-10-2018 A3L01_09145 d54da9629f715b97763116d6e16a56f8 480 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 1 198 18.503 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A3L01_09145 d54da9629f715b97763116d6e16a56f8 480 Pfam PF03853 YjeF-related protein N-terminus 21 182 1.1E-33 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A3L01_09145 d54da9629f715b97763116d6e16a56f8 480 SUPERFAMILY SSF64153 4 225 1.44E-48 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 A3L01_09145 d54da9629f715b97763116d6e16a56f8 480 SUPERFAMILY SSF53613 212 474 5.78E-60 T 23-10-2018 IPR029056 Ribokinase-like A3L01_09145 d54da9629f715b97763116d6e16a56f8 480 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 211 474 9.6E-71 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A3L01_09145 d54da9629f715b97763116d6e16a56f8 480 Gene3D G3DSA:3.40.50.10260 9 205 4.1E-42 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 A3L01_09145 d54da9629f715b97763116d6e16a56f8 480 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 8 183 2.0E-42 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A3L01_09145 d54da9629f715b97763116d6e16a56f8 480 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 415 425 - T 23-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site A3L01_09145 d54da9629f715b97763116d6e16a56f8 480 PIRSF PIRSF017184 2 479 1.2E-96 T 23-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 A3L01_09145 d54da9629f715b97763116d6e16a56f8 480 Pfam PF01256 Carbohydrate kinase 227 470 6.0E-51 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A3L01_09145 d54da9629f715b97763116d6e16a56f8 480 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 204 479 21.219 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A3L01_09145 d54da9629f715b97763116d6e16a56f8 480 Gene3D G3DSA:3.40.1190.20 210 477 9.0E-75 T 23-10-2018 IPR029056 Ribokinase-like A3L01_06170 8e55fb5f4795b91786af317da70b3d7b 480 PIRSF PIRSF001589 362 480 6.2E-19 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A3L01_06170 8e55fb5f4795b91786af317da70b3d7b 480 PIRSF PIRSF001589 1 373 2.3E-57 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A3L01_06170 8e55fb5f4795b91786af317da70b3d7b 480 SUPERFAMILY SSF56235 13 208 1.12E-42 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L01_06170 8e55fb5f4795b91786af317da70b3d7b 480 SUPERFAMILY SSF52402 221 458 1.51E-57 T 23-10-2018 A3L01_06170 8e55fb5f4795b91786af317da70b3d7b 480 Gene3D G3DSA:3.60.20.10 2 222 9.5E-48 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L01_06170 8e55fb5f4795b91786af317da70b3d7b 480 Pfam PF13537 Glutamine amidotransferase domain 61 179 9.0E-26 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A3L01_06170 8e55fb5f4795b91786af317da70b3d7b 480 Gene3D G3DSA:3.40.50.620 223 480 4.0E-71 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_06170 8e55fb5f4795b91786af317da70b3d7b 480 Pfam PF00733 Asparagine synthase 366 459 5.7E-21 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A3L01_06170 8e55fb5f4795b91786af317da70b3d7b 480 Pfam PF00733 Asparagine synthase 229 362 9.3E-32 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A3L01_00390 0250528c85780e6bbbe7d3014010b7a3 193 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 41 189 1.8E-27 T 23-10-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family A3L01_00390 0250528c85780e6bbbe7d3014010b7a3 193 Gene3D G3DSA:3.90.1720.10 45 167 6.7E-14 T 23-10-2018 A3L01_00390 0250528c85780e6bbbe7d3014010b7a3 193 SUPERFAMILY SSF54001 41 189 1.63E-27 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A3L01_04410 d03e0a09b437534d0bdd45380ac24835 209 Pfam PF01205 Uncharacterized protein family UPF0029 17 122 4.8E-32 T 23-10-2018 IPR001498 Impact, N-terminal A3L01_04410 d03e0a09b437534d0bdd45380ac24835 209 SUPERFAMILY SSF54980 135 198 4.75E-9 T 23-10-2018 IPR035647 EF-G domain III/V-like A3L01_04410 d03e0a09b437534d0bdd45380ac24835 209 SUPERFAMILY SSF54211 3 130 3.6E-41 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L01_04410 d03e0a09b437534d0bdd45380ac24835 209 Gene3D G3DSA:3.30.230.30 2 130 2.5E-46 T 23-10-2018 IPR036956 Impact, N-terminal domain superfamily A3L01_04410 d03e0a09b437534d0bdd45380ac24835 209 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 4 198 1.4E-53 T 23-10-2018 IPR015796 Impact family, bacterial/archaeal A3L01_04410 d03e0a09b437534d0bdd45380ac24835 209 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 78 107 - T 23-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site A3L01_04410 d03e0a09b437534d0bdd45380ac24835 209 Pfam PF09186 Domain of unknown function (DUF1949) 139 194 8.0E-12 T 23-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal A3L01_06935 96d20f5e4164aca92788efab219f8871 401 Pfam PF07690 Major Facilitator Superfamily 19 355 7.7E-19 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L01_06935 96d20f5e4164aca92788efab219f8871 401 SUPERFAMILY SSF103473 3 389 7.72E-32 T 23-10-2018 IPR036259 MFS transporter superfamily A3L01_06935 96d20f5e4164aca92788efab219f8871 401 Gene3D G3DSA:1.20.1250.20 2 185 6.3E-13 T 23-10-2018 A3L01_06935 96d20f5e4164aca92788efab219f8871 401 Gene3D G3DSA:1.20.1250.20 191 395 2.4E-5 T 23-10-2018 A3L01_08115 d7e79403f777e1c21a321a589872796a 304 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 142 169 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A3L01_08115 d7e79403f777e1c21a321a589872796a 304 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 304 4.0E-40 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A3L01_08115 d7e79403f777e1c21a321a589872796a 304 SUPERFAMILY SSF52283 2 134 6.24E-40 T 23-10-2018 A3L01_08115 d7e79403f777e1c21a321a589872796a 304 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 190 212 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A3L01_08115 d7e79403f777e1c21a321a589872796a 304 SUPERFAMILY SSF51735 97 281 5.24E-68 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_08115 d7e79403f777e1c21a321a589872796a 304 Gene3D G3DSA:3.40.50.720 7 298 2.1E-136 T 23-10-2018 A3L01_08115 d7e79403f777e1c21a321a589872796a 304 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 280 1.4E-72 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A3L01_08115 d7e79403f777e1c21a321a589872796a 304 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 219 235 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A3L01_08115 d7e79403f777e1c21a321a589872796a 304 Gene3D G3DSA:3.40.50.720 92 282 2.1E-136 T 23-10-2018 A3L01_02525 cdc9e556b60df235a98dec5331037bc1 493 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 96 469 3.0E-111 T 23-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 A3L01_02525 cdc9e556b60df235a98dec5331037bc1 493 Pfam PF02386 Cation transport protein 59 479 8.9E-67 T 23-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 A3L01_09735 36ff3734487913e1ce9091d2bfa3c5c8 466 SUPERFAMILY SSF52540 1 219 1.09E-25 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_09735 36ff3734487913e1ce9091d2bfa3c5c8 466 Pfam PF03008 Archaea bacterial proteins of unknown function 314 416 2.0E-22 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L01_09735 36ff3734487913e1ce9091d2bfa3c5c8 466 Gene3D G3DSA:3.40.50.300 1 167 1.1E-23 T 23-10-2018 A3L01_09735 36ff3734487913e1ce9091d2bfa3c5c8 466 Pfam PF01637 ATPase domain predominantly from Archaea 3 201 9.4E-12 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L01_10035 c65e5026e2855e9bd5aa8c40d4da0eef 421 Pfam PF07687 Peptidase dimerisation domain 206 317 2.0E-18 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A3L01_10035 c65e5026e2855e9bd5aa8c40d4da0eef 421 Gene3D G3DSA:3.30.70.360 209 341 2.7E-77 T 23-10-2018 A3L01_10035 c65e5026e2855e9bd5aa8c40d4da0eef 421 SUPERFAMILY SSF53187 5 419 7.04E-63 T 23-10-2018 A3L01_10035 c65e5026e2855e9bd5aa8c40d4da0eef 421 SUPERFAMILY SSF55031 211 321 9.94E-18 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A3L01_10035 c65e5026e2855e9bd5aa8c40d4da0eef 421 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 19 414 7.2E-78 T 23-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase A3L01_10035 c65e5026e2855e9bd5aa8c40d4da0eef 421 Pfam PF01546 Peptidase family M20/M25/M40 96 419 1.3E-37 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A3L01_10035 c65e5026e2855e9bd5aa8c40d4da0eef 421 Gene3D G3DSA:3.40.630.10 24 409 2.7E-77 T 23-10-2018 A3L01_10275 505af5f49419614693dafeaac14a37c2 333 SUPERFAMILY SSF51735 1 320 2.29E-94 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_10275 505af5f49419614693dafeaac14a37c2 333 Gene3D G3DSA:3.90.25.10 177 309 2.4E-131 T 23-10-2018 A3L01_10275 505af5f49419614693dafeaac14a37c2 333 Gene3D G3DSA:3.40.50.720 4 294 2.4E-131 T 23-10-2018 A3L01_10275 505af5f49419614693dafeaac14a37c2 333 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 304 4.0E-85 T 23-10-2018 IPR016040 NAD(P)-binding domain A3L01_10275 505af5f49419614693dafeaac14a37c2 333 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 318 1.9E-159 T 23-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 A3L01_03465 bdd59c4ee8774c3297b618344856f11b 289 SUPERFAMILY SSF103481 61 145 2.75E-13 T 23-10-2018 A3L01_03465 bdd59c4ee8774c3297b618344856f11b 289 SUPERFAMILY SSF103481 188 287 5.1E-13 T 23-10-2018 A3L01_03465 bdd59c4ee8774c3297b618344856f11b 289 Pfam PF00892 EamA-like transporter family 6 141 6.7E-23 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L01_03465 bdd59c4ee8774c3297b618344856f11b 289 Pfam PF00892 EamA-like transporter family 153 288 7.4E-25 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Gene3D G3DSA:3.40.50.200 390 522 1.0E-26 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SUPERFAMILY SSF49373 2044 2114 5.3E-8 T 23-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SUPERFAMILY SSF49299 735 818 7.85E-16 T 23-10-2018 IPR035986 PKD domain superfamily A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Pfam PF00801 PKD domain 743 804 1.4E-12 T 23-10-2018 IPR000601 PKD domain A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Pfam PF00801 PKD domain 1198 1260 1.5E-14 T 23-10-2018 IPR000601 PKD domain A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Pfam PF00801 PKD domain 648 713 1.1E-13 T 23-10-2018 IPR000601 PKD domain A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SUPERFAMILY SSF89260 525 634 2.22E-11 T 23-10-2018 A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SUPERFAMILY SSF49373 1287 1357 3.4E-7 T 23-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Gene3D G3DSA:2.60.120.380 523 636 4.2E-19 T 23-10-2018 A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Gene3D G3DSA:2.60.40.10 637 725 1.2E-25 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Gene3D G3DSA:2.60.40.10 1187 1274 1.5E-25 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Gene3D G3DSA:2.60.40.10 726 817 4.9E-17 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Pfam PF00082 Subtilase family 243 515 7.7E-21 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Gene3D G3DSA:3.40.50.200 162 322 1.2E-16 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SUPERFAMILY SSF49299 608 725 3.14E-26 T 23-10-2018 IPR035986 PKD domain superfamily A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SUPERFAMILY SSF49373 1561 1639 4.97E-9 T 23-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SMART SM00320 865 903 4.0 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SMART SM00320 1141 1183 0.69 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SMART SM00320 907 943 210.0 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SMART SM00320 823 864 170.0 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SUPERFAMILY SSF49373 1658 1732 1.83E-8 T 23-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Gene3D G3DSA:2.60.40.10 2128 2211 6.9E-9 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Gene3D G3DSA:2.60.40.10 1750 1833 3.0E-9 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Gene3D G3DSA:2.60.40.10 2034 2118 2.6E-9 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Gene3D G3DSA:2.60.40.10 1653 1737 4.6E-10 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Gene3D G3DSA:2.60.40.10 1938 2022 6.8E-9 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Gene3D G3DSA:2.60.40.10 1371 1452 4.3E-10 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Gene3D G3DSA:2.60.40.10 1843 1927 1.2E-8 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SUPERFAMILY SSF82171 823 1233 1.24E-15 T 23-10-2018 A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 467 477 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SMART SM00634 1846 1931 0.078 T 23-10-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SMART SM00634 1943 2026 0.15 T 23-10-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SMART SM00634 2131 2212 0.42 T 23-10-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SMART SM00634 1656 1741 0.015 T 23-10-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SMART SM00634 1561 1649 0.016 T 23-10-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SMART SM00634 2038 2124 0.061 T 23-10-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SMART SM00634 1374 1456 0.0062 T 23-10-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SMART SM00634 1752 1839 0.034 T 23-10-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SMART SM00634 1269 1361 0.54 T 23-10-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SUPERFAMILY SSF49373 1751 1829 2.41E-8 T 23-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Gene3D G3DSA:2.60.40.10 1279 1367 6.5E-8 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SUPERFAMILY SSF49373 1944 2019 6.02E-8 T 23-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SMART SM00089 643 726 8.3E-23 T 23-10-2018 IPR022409 PKD/Chitinase domain A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SMART SM00089 1193 1276 5.9E-24 T 23-10-2018 IPR022409 PKD/Chitinase domain A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SMART SM00089 733 819 3.0E-11 T 23-10-2018 IPR022409 PKD/Chitinase domain A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SUPERFAMILY SSF52743 133 530 1.7E-48 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SUPERFAMILY SSF49373 1851 1924 7.85E-8 T 23-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SUPERFAMILY SSF49299 1190 1274 1.01E-21 T 23-10-2018 IPR035986 PKD domain superfamily A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SUPERFAMILY SSF49373 2133 2209 4.97E-8 T 23-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SUPERFAMILY SSF49373 1469 1545 1.07E-5 T 23-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Pfam PF16640 Bacterial Ig-like domain (group 3) 1952 2030 3.5E-8 T 23-10-2018 IPR032109 Bacterial Ig-like domain (group 3) A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Pfam PF16640 Bacterial Ig-like domain (group 3) 1764 1847 3.2E-9 T 23-10-2018 IPR032109 Bacterial Ig-like domain (group 3) A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Pfam PF16640 Bacterial Ig-like domain (group 3) 1859 1936 4.2E-8 T 23-10-2018 IPR032109 Bacterial Ig-like domain (group 3) A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Pfam PF16640 Bacterial Ig-like domain (group 3) 1380 1466 2.8E-9 T 23-10-2018 IPR032109 Bacterial Ig-like domain (group 3) A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Pfam PF16640 Bacterial Ig-like domain (group 3) 1668 1744 1.7E-8 T 23-10-2018 IPR032109 Bacterial Ig-like domain (group 3) A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Pfam PF16640 Bacterial Ig-like domain (group 3) 1287 1361 7.7E-11 T 23-10-2018 IPR032109 Bacterial Ig-like domain (group 3) A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Pfam PF16640 Bacterial Ig-like domain (group 3) 2046 2132 4.6E-8 T 23-10-2018 IPR032109 Bacterial Ig-like domain (group 3) A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Pfam PF16640 Bacterial Ig-like domain (group 3) 1476 1556 3.8E-8 T 23-10-2018 IPR032109 Bacterial Ig-like domain (group 3) A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Pfam PF16640 Bacterial Ig-like domain (group 3) 1570 1657 6.0E-10 T 23-10-2018 IPR032109 Bacterial Ig-like domain (group 3) A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Gene3D G3DSA:2.60.40.10 1558 1645 7.3E-10 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Gene3D G3DSA:2.60.40.10 1466 1549 2.0E-5 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 SUPERFAMILY SSF49373 1381 1449 5.23E-8 T 23-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments A3L01_10245 07d55afa223220a8913a18c6815b5946 2212 Gene3D G3DSA:2.130.10.10 818 970 2.7E-7 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A3L01_05790 61b9685c0d82c723c3ccf544469ffc42 397 SUPERFAMILY SSF161093 15 189 3.27E-32 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 A3L01_05790 61b9685c0d82c723c3ccf544469ffc42 397 SUPERFAMILY SSF161093 224 395 4.32E-27 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 A3L01_05790 61b9685c0d82c723c3ccf544469ffc42 397 Pfam PF01769 Divalent cation transporter 263 388 3.9E-15 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A3L01_05790 61b9685c0d82c723c3ccf544469ffc42 397 Pfam PF01769 Divalent cation transporter 60 183 1.1E-21 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A3L01_05790 61b9685c0d82c723c3ccf544469ffc42 397 Gene3D G3DSA:1.10.357.20 11 189 2.3E-10 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain A3L01_05790 61b9685c0d82c723c3ccf544469ffc42 397 Gene3D G3DSA:1.10.357.20 217 395 7.0E-14 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain A3L01_03445 dbffc28f733e852534d586f8b53f26fc 237 Pfam PF01061 ABC-2 type transporter 4 203 1.9E-26 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A3L01_03445 dbffc28f733e852534d586f8b53f26fc 237 PIRSF PIRSF006648 1 236 6.8E-27 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L01_02640 f627beaad2f5bac993f7d4320b77db5a 263 Gene3D G3DSA:1.10.1670.10 21 250 2.5E-81 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A3L01_02640 f627beaad2f5bac993f7d4320b77db5a 263 Pfam PF09171 N-glycosylase/DNA lyase 23 243 1.8E-83 T 23-10-2018 IPR015254 N-glycosylase/DNA lyase-like GO:0003906|GO:0016799 A3L01_02640 f627beaad2f5bac993f7d4320b77db5a 263 PIRSF PIRSF008955 12 263 6.6E-101 T 23-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 A3L01_02640 f627beaad2f5bac993f7d4320b77db5a 263 Hamap MF_01168 N-glycosylase/DNA lyase. 20 257 38.878 T 23-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 A3L01_02640 f627beaad2f5bac993f7d4320b77db5a 263 SUPERFAMILY SSF48150 16 255 4.71E-80 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A3L01_02640 f627beaad2f5bac993f7d4320b77db5a 263 Gene3D G3DSA:1.10.340.30 41 188 2.5E-81 T 23-10-2018 A3L01_05140 a5688592e365591601ec070839adb30f 213 SMART SM00863 165 208 3.3E-7 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L01_05140 a5688592e365591601ec070839adb30f 213 Pfam PF01411 tRNA synthetases class II (A) 13 87 3.9E-13 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A3L01_05140 a5688592e365591601ec070839adb30f 213 Gene3D G3DSA:3.30.980.10 85 212 1.2E-40 T 23-10-2018 A3L01_05140 a5688592e365591601ec070839adb30f 213 Gene3D G3DSA:2.40.30.130 13 84 1.3E-32 T 23-10-2018 A3L01_05140 a5688592e365591601ec070839adb30f 213 SUPERFAMILY SSF55186 85 210 2.09E-32 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A3L01_05140 a5688592e365591601ec070839adb30f 213 SUPERFAMILY SSF50447 2 84 1.8E-21 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L01_05140 a5688592e365591601ec070839adb30f 213 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 170 208 5.3E-8 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L01_02740 98990a67c1bf043d40315d081879ab1b 273 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 46 73 - T 23-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 A3L01_02740 98990a67c1bf043d40315d081879ab1b 273 Gene3D G3DSA:3.40.50.150 2 194 1.1E-63 T 23-10-2018 A3L01_02740 98990a67c1bf043d40315d081879ab1b 273 SMART SM00650 30 193 2.1E-79 T 23-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 A3L01_02740 98990a67c1bf043d40315d081879ab1b 273 SUPERFAMILY SSF53335 11 266 3.95E-61 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_02740 98990a67c1bf043d40315d081879ab1b 273 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 15 262 7.2E-73 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A3L01_02740 98990a67c1bf043d40315d081879ab1b 273 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 14 267 45.0 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A3L01_02740 98990a67c1bf043d40315d081879ab1b 273 Gene3D G3DSA:1.10.8.100 195 271 3.8E-9 T 23-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 A3L01_02740 98990a67c1bf043d40315d081879ab1b 273 Pfam PF00398 Ribosomal RNA adenine dimethylase 14 225 1.3E-51 T 23-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm A3L01_06095 9b1d38275eb7e71a33ee1d71f0601ee1 1188 SUPERFAMILY SSF75553 485 677 2.09E-50 T 23-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 A3L01_06095 9b1d38275eb7e71a33ee1d71f0601ee1 1188 SUPERFAMILY SSF57997 668 938 9.81E-6 T 23-10-2018 A3L01_06095 9b1d38275eb7e71a33ee1d71f0601ee1 1188 Gene3D G3DSA:1.20.5.340 772 877 1.0E-7 T 23-10-2018 A3L01_06095 9b1d38275eb7e71a33ee1d71f0601ee1 1188 Gene3D G3DSA:1.20.5.340 369 486 2.2E-6 T 23-10-2018 A3L01_06095 9b1d38275eb7e71a33ee1d71f0601ee1 1188 Gene3D G3DSA:3.40.50.300 2 233 1.6E-60 T 23-10-2018 A3L01_06095 9b1d38275eb7e71a33ee1d71f0601ee1 1188 Gene3D G3DSA:3.30.70.1620 581 658 1.8E-45 T 23-10-2018 A3L01_06095 9b1d38275eb7e71a33ee1d71f0601ee1 1188 Gene3D G3DSA:3.40.50.300 1010 1181 1.1E-59 T 23-10-2018 A3L01_06095 9b1d38275eb7e71a33ee1d71f0601ee1 1188 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1161 3.0E-237 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A3L01_06095 9b1d38275eb7e71a33ee1d71f0601ee1 1188 Gene3D G3DSA:1.20.1060.20 507 661 1.8E-45 T 23-10-2018 A3L01_06095 9b1d38275eb7e71a33ee1d71f0601ee1 1188 Hamap MF_01894 Chromosome partition protein Smc [smc]. 2 1163 21.34 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A3L01_06095 9b1d38275eb7e71a33ee1d71f0601ee1 1188 Pfam PF06470 SMC proteins Flexible Hinge Domain 520 630 5.8E-33 T 23-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A3L01_06095 9b1d38275eb7e71a33ee1d71f0601ee1 1188 SUPERFAMILY SSF52540 1 1168 1.6E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06095 9b1d38275eb7e71a33ee1d71f0601ee1 1188 PIRSF PIRSF005719 1 1168 2.9E-282 T 23-10-2018 IPR024704 Structural maintenance of chromosomes protein A3L01_06095 9b1d38275eb7e71a33ee1d71f0601ee1 1188 SMART SM00968 520 632 1.1E-42 T 23-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A3L01_06095 9b1d38275eb7e71a33ee1d71f0601ee1 1188 SUPERFAMILY SSF57997 379 512 7.85E-7 T 23-10-2018 A3L01_06095 9b1d38275eb7e71a33ee1d71f0601ee1 1188 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1154 7.0E-69 T 23-10-2018 IPR003395 RecF/RecN/SMC, N-terminal A3L01_06095 9b1d38275eb7e71a33ee1d71f0601ee1 1188 TIGRFAM TIGR02169 SMC_prok_A: chromosome segregation protein SMC 3 1161 0.0 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A3L01_00995 e49509944f991724a023af584f91014d 182 PIRSF PIRSF005590 1 180 1.5E-69 T 23-10-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_00995 e49509944f991724a023af584f91014d 182 Pfam PF00252 Ribosomal protein L16p/L10e 14 159 1.1E-32 T 23-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A3L01_00995 e49509944f991724a023af584f91014d 182 ProSitePatterns PS01257 Ribosomal protein L10e signature. 105 126 - T 23-10-2018 IPR018255 Ribosomal protein L10e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_00995 e49509944f991724a023af584f91014d 182 Hamap MF_00448 50S ribosomal protein L10e [rpl10e]. 1 174 36.867 T 23-10-2018 IPR022981 Ribosomal protein L10e, archaea A3L01_00995 e49509944f991724a023af584f91014d 182 SUPERFAMILY SSF54686 4 166 1.16E-55 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 A3L01_00995 e49509944f991724a023af584f91014d 182 Gene3D G3DSA:3.90.1170.10 1 179 2.0E-64 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 A3L01_09005 42967b40890a10069268dd65a85f1320 438 SUPERFAMILY SSF51735 2 126 5.69E-22 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_09005 42967b40890a10069268dd65a85f1320 438 Gene3D G3DSA:3.40.50.261 287 438 7.8E-54 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L01_09005 42967b40890a10069268dd65a85f1320 438 SMART SM00881 4 98 7.7E-20 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L01_09005 42967b40890a10069268dd65a85f1320 438 Gene3D G3DSA:3.40.50.720 1 125 6.0E-31 T 23-10-2018 A3L01_09005 42967b40890a10069268dd65a85f1320 438 Gene3D G3DSA:3.40.50.261 135 286 2.9E-59 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L01_09005 42967b40890a10069268dd65a85f1320 438 SUPERFAMILY SSF52210 290 437 5.23E-41 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L01_09005 42967b40890a10069268dd65a85f1320 438 SUPERFAMILY SSF52210 128 283 1.7E-42 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L01_09005 42967b40890a10069268dd65a85f1320 438 Pfam PF13380 CoA binding domain 9 129 1.4E-16 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L01_09005 42967b40890a10069268dd65a85f1320 438 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 147 283 3.4E-57 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L01_04025 2925d6561ecc0223c46ceddde25ac809 273 SUPERFAMILY SSF52402 20 204 1.1E-32 T 23-10-2018 A3L01_04025 2925d6561ecc0223c46ceddde25ac809 273 PIRSF PIRSF036670 1 261 5.3E-126 T 23-10-2018 IPR012122 ATPase, PP-loop, MJ1016-related A3L01_04025 2925d6561ecc0223c46ceddde25ac809 273 Pfam PF06508 Queuosine biosynthesis protein QueC 23 82 2.1E-7 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L01_04025 2925d6561ecc0223c46ceddde25ac809 273 Gene3D G3DSA:3.40.50.620 19 226 2.1E-29 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_08470 cd14d4b81c724f712bad55dc58d6cfb8 101 Gene3D G3DSA:3.30.70.1750 5 99 2.0E-30 T 23-10-2018 A3L01_08470 cd14d4b81c724f712bad55dc58d6cfb8 101 Pfam PF11491 Protein of unknown function (DUF3213) 14 96 2.5E-36 T 23-10-2018 IPR021583 Protein of unknown function DUF3213 A3L01_02375 6f78f6f7b6f13707b861a23158be2da3 251 Gene3D G3DSA:3.40.50.1440 116 249 6.0E-7 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L01_02375 6f78f6f7b6f13707b861a23158be2da3 251 SUPERFAMILY SSF55307 159 247 4.58E-11 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A3L01_08970 4412f78d67a463481aa6030405473f98 385 SUPERFAMILY SSF53335 9 385 2.57E-55 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_08970 4412f78d67a463481aa6030405473f98 385 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 93 161 4.3E-7 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L01_08970 4412f78d67a463481aa6030405473f98 385 Gene3D G3DSA:2.30.130.10 89 164 2.6E-15 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L01_08970 4412f78d67a463481aa6030405473f98 385 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 10 86 2.2E-7 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L01_08970 4412f78d67a463481aa6030405473f98 385 Pfam PF01472 PUA domain 94 161 8.1E-17 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L01_08970 4412f78d67a463481aa6030405473f98 385 Gene3D G3DSA:3.40.50.150 191 385 7.8E-61 T 23-10-2018 A3L01_08970 4412f78d67a463481aa6030405473f98 385 Pfam PF01189 16S rRNA methyltransferase RsmB/F 194 383 1.3E-55 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L01_08970 4412f78d67a463481aa6030405473f98 385 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 205 215 4.1E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_08970 4412f78d67a463481aa6030405473f98 385 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 367 384 4.1E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_08970 4412f78d67a463481aa6030405473f98 385 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 176 190 4.1E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_08970 4412f78d67a463481aa6030405473f98 385 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 318 334 4.1E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_08970 4412f78d67a463481aa6030405473f98 385 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 271 283 4.1E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_08970 4412f78d67a463481aa6030405473f98 385 SUPERFAMILY SSF88697 91 162 3.76E-17 T 23-10-2018 IPR015947 PUA-like superfamily A3L01_08970 4412f78d67a463481aa6030405473f98 385 Gene3D G3DSA:3.30.70.3130 3 88 2.6E-12 T 23-10-2018 A3L01_08970 4412f78d67a463481aa6030405473f98 385 SMART SM00359 92 166 6.2E-20 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L01_04020 a03308653d2e55efde60144fd15f62f3 330 SUPERFAMILY SSF55326 6 147 7.15E-22 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L01_04020 a03308653d2e55efde60144fd15f62f3 330 SUPERFAMILY SSF56042 152 314 1.36E-27 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L01_04020 a03308653d2e55efde60144fd15f62f3 330 Gene3D G3DSA:3.90.650.10 152 327 5.1E-31 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L01_04020 a03308653d2e55efde60144fd15f62f3 330 Pfam PF02769 AIR synthase related protein, C-terminal domain 154 305 2.8E-16 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L01_04020 a03308653d2e55efde60144fd15f62f3 330 Gene3D G3DSA:3.30.1330.10 4 146 1.4E-23 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L01_04020 a03308653d2e55efde60144fd15f62f3 330 PIRSF PIRSF005644 1 329 4.3E-62 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A3L01_04020 a03308653d2e55efde60144fd15f62f3 330 Pfam PF00586 AIR synthase related protein, N-terminal domain 49 143 3.0E-14 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L01_09080 1ee8d16e2cdf13948618b4e7dbee1d09 338 Gene3D G3DSA:3.40.50.720 116 266 1.2E-26 T 23-10-2018 A3L01_09080 1ee8d16e2cdf13948618b4e7dbee1d09 338 SUPERFAMILY SSF51735 116 264 3.66E-21 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_09080 1ee8d16e2cdf13948618b4e7dbee1d09 338 SUPERFAMILY SSF81324 10 137 2.22E-29 T 23-10-2018 A3L01_09080 1ee8d16e2cdf13948618b4e7dbee1d09 338 Pfam PF02254 TrkA-N domain 121 241 1.3E-17 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A3L01_09080 1ee8d16e2cdf13948618b4e7dbee1d09 338 PRINTS PR01333 Two pore domain K+ channel signature 57 85 3.1E-7 T 23-10-2018 IPR003280 Two pore domain potassium channel GO:0005267|GO:0016020|GO:0071805 Reactome: R-HSA-5576886 A3L01_09080 1ee8d16e2cdf13948618b4e7dbee1d09 338 PRINTS PR01333 Two pore domain K+ channel signature 121 130 3.1E-7 T 23-10-2018 IPR003280 Two pore domain potassium channel GO:0005267|GO:0016020|GO:0071805 Reactome: R-HSA-5576886 A3L01_09080 1ee8d16e2cdf13948618b4e7dbee1d09 338 Pfam PF07885 Ion channel 29 101 3.1E-17 T 23-10-2018 IPR013099 Potassium channel domain A3L01_09080 1ee8d16e2cdf13948618b4e7dbee1d09 338 Gene3D G3DSA:1.10.287.70 5 102 1.7E-22 T 23-10-2018 A3L01_06530 29b176b9367abb822fbb48f99467d1df 211 TIGRFAM TIGR01491 HAD-SF-IB-PSPlk: phosphoserine phosphatase-like hydrolase, archaeal 1 183 1.1E-57 T 23-10-2018 IPR006386 HAD-superfamily hydrolase, subfamily IB, PSPase-like, archaeal A3L01_06530 29b176b9367abb822fbb48f99467d1df 211 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 4 173 1.4E-34 T 23-10-2018 A3L01_06530 29b176b9367abb822fbb48f99467d1df 211 Gene3D G3DSA:3.40.50.1000 1 202 6.5E-51 T 23-10-2018 IPR023214 HAD superfamily A3L01_06530 29b176b9367abb822fbb48f99467d1df 211 SUPERFAMILY SSF56784 2 204 3.07E-42 T 23-10-2018 IPR036412 HAD-like superfamily A3L01_06530 29b176b9367abb822fbb48f99467d1df 211 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 172 7.0E-18 T 23-10-2018 A3L01_01850 ae34a709b911a5286d2cbc32d91aec83 275 SUPERFAMILY SSF116742 85 174 7.98E-24 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L01_01850 ae34a709b911a5286d2cbc32d91aec83 275 Gene3D G3DSA:3.30.70.1130 173 262 2.6E-32 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L01_01850 ae34a709b911a5286d2cbc32d91aec83 275 SMART SM00316 10 83 8.3E-24 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L01_01850 ae34a709b911a5286d2cbc32d91aec83 275 SUPERFAMILY SSF50249 7 87 7.86E-21 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_01850 ae34a709b911a5286d2cbc32d91aec83 275 Gene3D G3DSA:2.40.50.140 3 85 6.7E-32 T 23-10-2018 A3L01_01850 ae34a709b911a5286d2cbc32d91aec83 275 Pfam PF07541 Eukaryotic translation initiation factor 2 alpha subunit 122 233 4.2E-23 T 23-10-2018 IPR011488 Translation initiation factor 2, alpha subunit GO:0003723|GO:0003743 Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L01_01850 ae34a709b911a5286d2cbc32d91aec83 275 Gene3D G3DSA:1.10.150.190 86 171 5.2E-33 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L01_01850 ae34a709b911a5286d2cbc32d91aec83 275 SUPERFAMILY SSF110993 176 260 7.59E-22 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L01_01850 ae34a709b911a5286d2cbc32d91aec83 275 Pfam PF00575 S1 RNA binding domain 9 83 7.9E-14 T 23-10-2018 IPR003029 S1 domain GO:0003676 A3L01_01850 ae34a709b911a5286d2cbc32d91aec83 275 Hamap MF_00231 Translation initiation factor 2 subunit alpha [eif2a]. 3 263 33.915 T 23-10-2018 IPR022964 Translation initiation factor 2, alpha subunit, archaeal A3L01_02850 142e7a38e4f0286c74c8502f1d567cb5 219 Gene3D G3DSA:3.40.1280.10 1 218 4.8E-76 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L01_02850 142e7a38e4f0286c74c8502f1d567cb5 219 Pfam PF03587 EMG1/NEP1 methyltransferase 5 215 2.7E-51 T 23-10-2018 IPR005304 Ribosomal biogenesis, methyltransferase, EMG1/NEP1 GO:0008168 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A3L01_02850 142e7a38e4f0286c74c8502f1d567cb5 219 SUPERFAMILY SSF75217 1 216 3.66E-63 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L01_02850 142e7a38e4f0286c74c8502f1d567cb5 219 Hamap MF_00554 Ribosomal RNA small subunit methyltransferase Nep1 [nep1]. 2 216 40.819 T 23-10-2018 IPR023503 Ribosome biogenesis methyltransferase NEP1, archaea GO:0008168 A3L01_07185 dd0d1193b3e296358f2769c5159e073f 202 TIGRFAM TIGR03334 IOR_beta: indolepyruvate ferredoxin oxidoreductase, beta subunit 4 194 1.1E-92 T 23-10-2018 IPR017719 Indolepyruvate ferredoxin oxidoreductase, beta subunit GO:0043805|GO:0055114 A3L01_07185 dd0d1193b3e296358f2769c5159e073f 202 Gene3D G3DSA:3.40.920.10 1 201 5.6E-50 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L01_07185 dd0d1193b3e296358f2769c5159e073f 202 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 193 4.1E-39 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L01_07185 dd0d1193b3e296358f2769c5159e073f 202 SUPERFAMILY SSF53323 4 199 3.01E-44 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L01_01570 124e2820276bf99fb97ccd40bef0133a 227 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 4 223 5.5E-82 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A3L01_01570 124e2820276bf99fb97ccd40bef0133a 227 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 51 221 5.9E-66 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A3L01_01570 124e2820276bf99fb97ccd40bef0133a 227 SUPERFAMILY SSF75445 131 207 3.92E-25 T 23-10-2018 A3L01_01570 124e2820276bf99fb97ccd40bef0133a 227 Gene3D G3DSA:3.30.70.260 127 205 5.9E-90 T 23-10-2018 A3L01_01570 124e2820276bf99fb97ccd40bef0133a 227 Gene3D G3DSA:3.40.50.1360 5 221 5.9E-90 T 23-10-2018 A3L01_01570 124e2820276bf99fb97ccd40bef0133a 227 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 225 36.452 T 23-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A3L01_01570 124e2820276bf99fb97ccd40bef0133a 227 SUPERFAMILY SSF100950 2 149 7.99E-46 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L01_06280 d78f17efad245a52a44885047055b73d 201 Gene3D G3DSA:3.40.50.620 2 200 6.4E-64 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_06280 d78f17efad245a52a44885047055b73d 201 SUPERFAMILY SSF52402 6 153 1.17E-22 T 23-10-2018 A3L01_06280 d78f17efad245a52a44885047055b73d 201 Pfam PF00733 Asparagine synthase 8 67 4.1E-5 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A3L01_00930 c47c4148846203961652225a4b5b9699 291 Pfam PF00175 Oxidoreductase NAD-binding domain 116 229 1.8E-12 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A3L01_00930 c47c4148846203961652225a4b5b9699 291 Gene3D G3DSA:2.10.240.10 249 283 3.8E-8 T 23-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily A3L01_00930 c47c4148846203961652225a4b5b9699 291 Pfam PF00970 Oxidoreductase FAD-binding domain 15 102 5.7E-9 T 23-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A3L01_00930 c47c4148846203961652225a4b5b9699 291 PIRSF PIRSF006816 5 291 4.4E-84 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L01_00930 c47c4148846203961652225a4b5b9699 291 Gene3D G3DSA:3.40.50.80 105 248 5.9E-23 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L01_00930 c47c4148846203961652225a4b5b9699 291 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 248 282 4.8E-13 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L01_00930 c47c4148846203961652225a4b5b9699 291 SUPERFAMILY SSF52343 99 282 6.68E-31 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L01_00930 c47c4148846203961652225a4b5b9699 291 SUPERFAMILY SSF63380 4 107 3.4E-24 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L01_00930 c47c4148846203961652225a4b5b9699 291 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 115 134 2.3E-7 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A3L01_00930 c47c4148846203961652225a4b5b9699 291 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 152 163 2.3E-7 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A3L01_00930 c47c4148846203961652225a4b5b9699 291 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 216 224 2.3E-7 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A3L01_00930 c47c4148846203961652225a4b5b9699 291 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 140 149 2.3E-7 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A3L01_00930 c47c4148846203961652225a4b5b9699 291 Gene3D G3DSA:2.40.30.10 3 103 2.8E-20 T 23-10-2018 A3L01_00930 c47c4148846203961652225a4b5b9699 291 PRINTS PR00410 Phenol hydroxylase reductase family signature 140 149 2.1E-10 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L01_00930 c47c4148846203961652225a4b5b9699 291 PRINTS PR00410 Phenol hydroxylase reductase family signature 216 224 2.1E-10 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L01_00930 c47c4148846203961652225a4b5b9699 291 PRINTS PR00410 Phenol hydroxylase reductase family signature 41 53 2.1E-10 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L01_00930 c47c4148846203961652225a4b5b9699 291 PRINTS PR00410 Phenol hydroxylase reductase family signature 115 134 2.1E-10 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L01_06735 f207c113bc2320dceeda4f8aedbd403f 388 Gene3D G3DSA:3.40.190.10 112 274 7.9E-65 T 23-10-2018 A3L01_06735 f207c113bc2320dceeda4f8aedbd403f 388 Gene3D G3DSA:3.40.190.10 3 345 7.9E-65 T 23-10-2018 A3L01_06735 f207c113bc2320dceeda4f8aedbd403f 388 SUPERFAMILY SSF53850 1 386 6.42E-69 T 23-10-2018 A3L01_06735 f207c113bc2320dceeda4f8aedbd403f 388 Pfam PF01547 Bacterial extracellular solute-binding protein 12 305 8.4E-38 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein A3L01_07555 1ee7971972226cefa92cd6d045a209c2 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 262 1.2E-57 T 23-10-2018 A3L01_07555 1ee7971972226cefa92cd6d045a209c2 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 9.7E-11 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_07555 1ee7971972226cefa92cd6d045a209c2 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 9.7E-11 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_07555 1ee7971972226cefa92cd6d045a209c2 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 9.7E-11 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_07555 1ee7971972226cefa92cd6d045a209c2 265 Gene3D G3DSA:3.40.50.720 3 264 1.4E-72 T 23-10-2018 A3L01_07555 1ee7971972226cefa92cd6d045a209c2 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 2.3E-39 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_07555 1ee7971972226cefa92cd6d045a209c2 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 2.3E-39 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_07555 1ee7971972226cefa92cd6d045a209c2 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 2.3E-39 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_07555 1ee7971972226cefa92cd6d045a209c2 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.3E-39 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_07555 1ee7971972226cefa92cd6d045a209c2 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 2.3E-39 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_07555 1ee7971972226cefa92cd6d045a209c2 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 2.3E-39 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_07555 1ee7971972226cefa92cd6d045a209c2 265 SUPERFAMILY SSF51735 14 263 2.88E-72 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_01360 db883413055f61164f6fa4f0f2e94e10 278 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 76 91 - T 23-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L01_01360 db883413055f61164f6fa4f0f2e94e10 278 SUPERFAMILY SSF53167 18 247 1.09E-74 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A3L01_01360 db883413055f61164f6fa4f0f2e94e10 278 Pfam PF01048 Phosphorylase superfamily 31 249 1.1E-44 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A3L01_01360 db883413055f61164f6fa4f0f2e94e10 278 Gene3D G3DSA:3.40.50.1580 7 261 4.0E-85 T 23-10-2018 A3L01_01360 db883413055f61164f6fa4f0f2e94e10 278 TIGRFAM TIGR01718 Uridine-psphlse: uridine phosphorylase 18 257 3.0E-97 T 23-10-2018 IPR010058 Uridine phosphorylase GO:0004850|GO:0005737|GO:0009166 KEGG: 00240+2.4.2.3|KEGG: 00983+2.4.2.3|MetaCyc: PWY-5532 A3L01_08350 6f76ffc4a920b023a73e06706b550d5c 121 SUPERFAMILY SSF53706 5 62 1.1E-5 T 23-10-2018 A3L01_08350 6f76ffc4a920b023a73e06706b550d5c 121 Gene3D G3DSA:3.10.530.10 51 119 4.8E-24 T 23-10-2018 IPR036593 CPE0013-like superfamily A3L01_08350 6f76ffc4a920b023a73e06706b550d5c 121 Pfam PF07892 Protein of unknown function (DUF1667) 38 119 5.7E-32 T 23-10-2018 IPR012460 Protein of unknown function DUF1667 A3L01_08350 6f76ffc4a920b023a73e06706b550d5c 121 SUPERFAMILY SSF160148 50 120 1.07E-23 T 23-10-2018 IPR036593 CPE0013-like superfamily A3L01_06730 057e14382f40a31b698e2efd51d1f673 295 SUPERFAMILY SSF161098 53 280 2.49E-58 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_06730 057e14382f40a31b698e2efd51d1f673 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 290 1.1E-17 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_06730 057e14382f40a31b698e2efd51d1f673 295 Gene3D G3DSA:1.10.3720.10 49 291 5.7E-63 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_06730 057e14382f40a31b698e2efd51d1f673 295 SUPERFAMILY SSF160964 16 49 4.45E-6 T 23-10-2018 A3L01_01420 45d44113451860d82e8ec55ebb005d1a 440 Pfam PF00753 Metallo-beta-lactamase superfamily 13 183 2.7E-15 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_01420 45d44113451860d82e8ec55ebb005d1a 440 Gene3D G3DSA:3.40.50.10710 215 374 1.9E-136 T 23-10-2018 A3L01_01420 45d44113451860d82e8ec55ebb005d1a 440 Gene3D G3DSA:3.60.15.10 3 439 1.9E-136 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_01420 45d44113451860d82e8ec55ebb005d1a 440 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 378 406 - T 23-10-2018 IPR001587 Ribonuclease J, conserved site A3L01_01420 45d44113451860d82e8ec55ebb005d1a 440 SMART SM00849 14 221 3.3E-26 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_01420 45d44113451860d82e8ec55ebb005d1a 440 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 2 440 6.1E-162 T 23-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 A3L01_01420 45d44113451860d82e8ec55ebb005d1a 440 SUPERFAMILY SSF56281 2 439 7.39E-67 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_01420 45d44113451860d82e8ec55ebb005d1a 440 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 371 421 9.4E-13 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A3L01_01420 45d44113451860d82e8ec55ebb005d1a 440 Hamap MF_01492 Ribonuclease J [rnj]. 1 440 50.016 T 23-10-2018 IPR030879 Ribonuclease J, archaea GO:0003723|GO:0004534|GO:0090503 A3L01_06535 406e7366e27b7032f54ba307fcf66665 220 SUPERFAMILY SSF53335 6 214 2.68E-54 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_06535 406e7366e27b7032f54ba307fcf66665 220 Gene3D G3DSA:3.40.50.150 1 220 3.1E-95 T 23-10-2018 A3L01_06535 406e7366e27b7032f54ba307fcf66665 220 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 137 152 - T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A3L01_06535 406e7366e27b7032f54ba307fcf66665 220 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 5 218 41.492 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A3L01_06535 406e7366e27b7032f54ba307fcf66665 220 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 12 215 4.6E-68 T 23-10-2018 A3L01_06535 406e7366e27b7032f54ba307fcf66665 220 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 9 216 7.0E-63 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A3L01_08265 0b255c99f7a584e40db4ebd57ae3189c 177 SMART SM00531 19 158 1.0E-56 T 23-10-2018 IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal GO:0006367 Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L01_08265 0b255c99f7a584e40db4ebd57ae3189c 177 PIRSF PIRSF006373 1 177 3.4E-70 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 A3L01_08265 0b255c99f7a584e40db4ebd57ae3189c 177 TIGRFAM TIGR00373 TIGR00373: transcription factor E 11 164 9.9E-49 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 A3L01_08265 0b255c99f7a584e40db4ebd57ae3189c 177 SUPERFAMILY SSF46785 6 87 2.3E-24 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_08265 0b255c99f7a584e40db4ebd57ae3189c 177 Pfam PF02002 TFIIE alpha subunit 11 110 1.8E-24 T 23-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L01_08265 0b255c99f7a584e40db4ebd57ae3189c 177 Hamap MF_01909 Transcription factor E [tfe]. 3 166 26.745 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 A3L01_08265 0b255c99f7a584e40db4ebd57ae3189c 177 Gene3D G3DSA:1.10.10.10 4 87 5.0E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_03640 cc83851bc9cdb8434518236841149747 281 SUPERFAMILY SSF52518 19 259 6.08E-75 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L01_03640 cc83851bc9cdb8434518236841149747 281 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 56 202 3.5E-35 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L01_03640 cc83851bc9cdb8434518236841149747 281 Gene3D G3DSA:3.40.50.970 86 248 6.4E-28 T 23-10-2018 A3L01_02985 a0ebbc44ca63688b8107cc1f68a2ad63 92 Pfam PF09341 Transcription factor Pcc1 20 90 2.7E-12 T 23-10-2018 IPR015419 CTAG/Pcc1 family A3L01_02985 a0ebbc44ca63688b8107cc1f68a2ad63 92 Gene3D G3DSA:3.30.310.50 7 92 3.8E-24 T 23-10-2018 A3L01_07285 c100182c37e6ecad20b281a03af8e2b5 280 Gene3D G3DSA:3.80.30.30 51 254 1.4E-12 T 23-10-2018 A3L01_07285 c100182c37e6ecad20b281a03af8e2b5 280 SUPERFAMILY SSF102114 9 217 2.22E-16 T 23-10-2018 A3L01_07285 c100182c37e6ecad20b281a03af8e2b5 280 Pfam PF04055 Radical SAM superfamily 23 187 2.6E-15 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L01_07285 c100182c37e6ecad20b281a03af8e2b5 280 SMART SM00729 18 228 1.3E-13 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L01_08620 84969f1f2e84d680187474ef89a68fe6 75 SUPERFAMILY SSF54909 1 74 9.52E-18 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L01_08620 84969f1f2e84d680187474ef89a68fe6 75 Pfam PF01037 Lrp/AsnC ligand binding domain 9 74 2.3E-18 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L01_08620 84969f1f2e84d680187474ef89a68fe6 75 Gene3D G3DSA:3.30.70.920 1 74 8.7E-27 T 23-10-2018 A3L01_03325 d1cb7677ede4b263d23edb3eb7387609 337 SUPERFAMILY SSF55608 153 276 4.48E-12 T 23-10-2018 IPR027434 Homing endonuclease A3L01_03325 d1cb7677ede4b263d23edb3eb7387609 337 Pfam PF14528 LAGLIDADG-like domain 165 257 1.1E-11 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L01_03325 d1cb7677ede4b263d23edb3eb7387609 337 Gene3D G3DSA:3.10.28.10 71 235 3.8E-14 T 23-10-2018 IPR027434 Homing endonuclease A3L01_03325 d1cb7677ede4b263d23edb3eb7387609 337 Pfam PF14527 WhiA LAGLIDADG-like domain 75 123 5.6E-4 T 23-10-2018 IPR039518 WhiA, LAGLIDADG-like domain A3L01_03325 d1cb7677ede4b263d23edb3eb7387609 337 PRINTS PR00379 Intein signature 74 86 3.9E-6 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_03325 d1cb7677ede4b263d23edb3eb7387609 337 PRINTS PR00379 Intein signature 165 177 3.9E-6 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_03325 d1cb7677ede4b263d23edb3eb7387609 337 PRINTS PR00379 Intein signature 198 213 3.9E-6 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_03325 d1cb7677ede4b263d23edb3eb7387609 337 SUPERFAMILY SSF55608 69 146 5.26E-9 T 23-10-2018 IPR027434 Homing endonuclease A3L01_08045 1da6310c04ba8c93cce3a945a4d6ebf9 453 PIRSF PIRSF004919 1 453 1.3E-159 T 23-10-2018 IPR025502 TldD A3L01_08045 1da6310c04ba8c93cce3a945a4d6ebf9 453 Pfam PF01523 Putative modulator of DNA gyrase 19 307 5.6E-62 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L01_08045 1da6310c04ba8c93cce3a945a4d6ebf9 453 SUPERFAMILY SSF111283 2 447 3.4E-113 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L01_08045 1da6310c04ba8c93cce3a945a4d6ebf9 453 Gene3D G3DSA:3.30.2290.10 1 188 5.9E-18 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L01_02180 6f9ada8a7e3baf075532aff539164e29 152 SMART SM00738 3 87 4.0E-21 T 23-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A3L01_02180 6f9ada8a7e3baf075532aff539164e29 152 SMART SM00739 92 119 4.2E-7 T 23-10-2018 IPR005824 KOW A3L01_02180 6f9ada8a7e3baf075532aff539164e29 152 Gene3D G3DSA:2.30.30.30 88 152 4.0E-28 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L01_02180 6f9ada8a7e3baf075532aff539164e29 152 Pfam PF00467 KOW motif 95 126 1.3E-8 T 23-10-2018 IPR005824 KOW A3L01_02180 6f9ada8a7e3baf075532aff539164e29 152 Hamap MF_00950 Transcription elongation factor Spt5 [spt5]. 5 148 38.679 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 A3L01_02180 6f9ada8a7e3baf075532aff539164e29 152 Pfam PF03439 Early transcription elongation factor of RNA pol II, NGN section 5 84 2.9E-24 T 23-10-2018 IPR005100 NGN domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A3L01_02180 6f9ada8a7e3baf075532aff539164e29 152 TIGRFAM TIGR00405 KOW_elon_Spt5: transcription elongation factor Spt5 7 150 1.6E-52 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 A3L01_02180 6f9ada8a7e3baf075532aff539164e29 152 SUPERFAMILY SSF50104 55 147 2.86E-17 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L01_02180 6f9ada8a7e3baf075532aff539164e29 152 Gene3D G3DSA:3.30.70.940 2 87 2.7E-34 T 23-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A3L01_01940 e800635e6a75f4ace467b5f70e236de8 145 SUPERFAMILY SSF54814 13 74 7.85E-12 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L01_01940 e800635e6a75f4ace467b5f70e236de8 145 Pfam PF07650 KH domain 14 94 8.7E-18 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01940 e800635e6a75f4ace467b5f70e236de8 145 Gene3D G3DSA:3.30.300.20 2 73 2.1E-27 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L01_01940 e800635e6a75f4ace467b5f70e236de8 145 Gene3D G3DSA:3.30.300.20 74 144 2.3E-22 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L01_01940 e800635e6a75f4ace467b5f70e236de8 145 Hamap MF_00945_A Transcription termination/antitermination protein NusA [nusA]. 1 145 30.059 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal A3L01_01940 e800635e6a75f4ace467b5f70e236de8 145 SUPERFAMILY SSF54814 88 141 6.28E-7 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L01_01940 e800635e6a75f4ace467b5f70e236de8 145 SMART SM00322 32 115 0.0014 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L01_01940 e800635e6a75f4ace467b5f70e236de8 145 TIGRFAM TIGR01952 nusA_arch: NusA family KH domain protein, archaeal 1 145 4.1E-60 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal A3L01_05915 dd9c4201a52afc7ee61654f2fed617e9 642 SUPERFAMILY SSF52540 7 232 6.77E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_05915 dd9c4201a52afc7ee61654f2fed617e9 642 SMART SM00491 466 608 2.1E-46 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A3L01_05915 dd9c4201a52afc7ee61654f2fed617e9 642 Pfam PF06777 Helical and beta-bridge domain 244 435 4.2E-67 T 23-10-2018 IPR010643 Helical and beta-bridge domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-2564830|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 A3L01_05915 dd9c4201a52afc7ee61654f2fed617e9 642 SUPERFAMILY SSF52540 34 625 1.66E-5 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_05915 dd9c4201a52afc7ee61654f2fed617e9 642 Gene3D G3DSA:1.10.30.20 99 175 5.1E-115 T 23-10-2018 A3L01_05915 dd9c4201a52afc7ee61654f2fed617e9 642 TIGRFAM TIGR00604 rad3: DNA repair helicase (rad3) 9 631 2.3E-146 T 23-10-2018 IPR013020 ATP-dependent helicase Rad3/Chl1-like GO:0004003 A3L01_05915 dd9c4201a52afc7ee61654f2fed617e9 642 Gene3D G3DSA:3.40.50.300 24 403 5.1E-115 T 23-10-2018 A3L01_05915 dd9c4201a52afc7ee61654f2fed617e9 642 Pfam PF13307 Helicase C-terminal domain 449 621 4.2E-38 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A3L01_05915 dd9c4201a52afc7ee61654f2fed617e9 642 Pfam PF06733 DEAD_2 68 239 6.6E-34 T 23-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 A3L01_05915 dd9c4201a52afc7ee61654f2fed617e9 642 SMART SM00487 12 270 1.4E-9 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L01_05915 dd9c4201a52afc7ee61654f2fed617e9 642 Gene3D G3DSA:3.40.50.300 418 633 6.7E-43 T 23-10-2018 A3L01_05915 dd9c4201a52afc7ee61654f2fed617e9 642 SMART SM00488 7 258 1.1E-78 T 23-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 A3L01_05915 dd9c4201a52afc7ee61654f2fed617e9 642 Gene3D G3DSA:1.10.275.40 234 371 5.1E-115 T 23-10-2018 A3L01_01130 148e56f6f1ec0e9dc8a30cb1cef94ef4 201 Pfam PF14204 Ribosomal L18 C-terminal region 143 194 2.6E-13 T 23-10-2018 IPR025607 Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01130 148e56f6f1ec0e9dc8a30cb1cef94ef4 201 SUPERFAMILY SSF53137 2 195 2.35E-63 T 23-10-2018 A3L01_01130 148e56f6f1ec0e9dc8a30cb1cef94ef4 201 Gene3D G3DSA:3.30.420.100 1 198 9.2E-72 T 23-10-2018 A3L01_01130 148e56f6f1ec0e9dc8a30cb1cef94ef4 201 Hamap MF_01337_A 50S ribosomal protein L18 [rplR]. 5 192 44.805 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01130 148e56f6f1ec0e9dc8a30cb1cef94ef4 201 PRINTS PR00058 Ribosomal protein L5 signature 123 142 6.7E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01130 148e56f6f1ec0e9dc8a30cb1cef94ef4 201 PRINTS PR00058 Ribosomal protein L5 signature 1 12 6.7E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01130 148e56f6f1ec0e9dc8a30cb1cef94ef4 201 PRINTS PR00058 Ribosomal protein L5 signature 103 122 6.7E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01130 148e56f6f1ec0e9dc8a30cb1cef94ef4 201 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 6 94 5.4E-14 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01130 148e56f6f1ec0e9dc8a30cb1cef94ef4 201 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 100 134 1.0E-8 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_00235 ebc5cd9f431362c094a593f1d1fc9c8c 177 Pfam PF04019 Protein of unknown function (DUF359) 50 171 4.7E-40 T 23-10-2018 IPR007164 Protein of unknown function DUF359 A3L01_00235 ebc5cd9f431362c094a593f1d1fc9c8c 177 PIRSF PIRSF006533 1 175 2.3E-56 T 23-10-2018 IPR007164 Protein of unknown function DUF359 A3L01_00235 ebc5cd9f431362c094a593f1d1fc9c8c 177 Hamap MF_00590 UPF0218 protein . 6 173 29.799 T 23-10-2018 IPR007164 Protein of unknown function DUF359 A3L01_01555 d1aeef9f90881f6ee313e0cb6a062d78 648 SUPERFAMILY SSF56281 183 647 8.29E-132 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_01555 d1aeef9f90881f6ee313e0cb6a062d78 648 Gene3D G3DSA:3.30.300.20 72 142 2.9E-64 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L01_01555 d1aeef9f90881f6ee313e0cb6a062d78 648 TIGRFAM TIGR03675 arCOG00543: arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein 13 647 7.6E-299 T 23-10-2018 IPR019975 KH-domain/beta-lactamase-domain protein, archaea A3L01_01555 d1aeef9f90881f6ee313e0cb6a062d78 648 SUPERFAMILY SSF54814 95 141 1.96E-5 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L01_01555 d1aeef9f90881f6ee313e0cb6a062d78 648 SMART SM00849 198 428 4.0E-27 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_01555 d1aeef9f90881f6ee313e0cb6a062d78 648 Gene3D G3DSA:3.40.50.10890 401 588 1.2E-164 T 23-10-2018 A3L01_01555 d1aeef9f90881f6ee313e0cb6a062d78 648 Pfam PF10996 Beta-Casp domain 433 556 4.5E-24 T 23-10-2018 IPR022712 Beta-Casp domain A3L01_01555 d1aeef9f90881f6ee313e0cb6a062d78 648 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 576 639 8.1E-19 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A3L01_01555 d1aeef9f90881f6ee313e0cb6a062d78 648 Gene3D G3DSA:3.60.15.10 191 627 1.2E-164 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_01555 d1aeef9f90881f6ee313e0cb6a062d78 648 SMART SM00322 102 169 3.6E-5 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L01_01555 d1aeef9f90881f6ee313e0cb6a062d78 648 Gene3D G3DSA:3.30.300.230 17 176 2.9E-64 T 23-10-2018 A3L01_01555 d1aeef9f90881f6ee313e0cb6a062d78 648 Pfam PF17214 KH domain 9 76 1.8E-27 T 23-10-2018 IPR033769 KH domain, archaeal A3L01_01555 d1aeef9f90881f6ee313e0cb6a062d78 648 Pfam PF16661 Metallo-beta-lactamase superfamily domain 204 351 1.3E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_01555 d1aeef9f90881f6ee313e0cb6a062d78 648 SMART SM01027 433 557 3.2E-57 T 23-10-2018 IPR022712 Beta-Casp domain A3L01_07925 74353b71f8b5193be6b9a46c722950b3 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 80 89 3.6E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L01_07925 74353b71f8b5193be6b9a46c722950b3 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 225 234 3.6E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L01_07925 74353b71f8b5193be6b9a46c722950b3 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 3.6E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L01_07925 74353b71f8b5193be6b9a46c722950b3 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 286 300 3.6E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L01_07925 74353b71f8b5193be6b9a46c722950b3 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 3.6E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L01_07925 74353b71f8b5193be6b9a46c722950b3 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 41 63 3.6E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L01_07925 74353b71f8b5193be6b9a46c722950b3 308 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 6 147 2.2E-49 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A3L01_07925 74353b71f8b5193be6b9a46c722950b3 308 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 6 304 1.1E-131 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L01_07925 74353b71f8b5193be6b9a46c722950b3 308 Gene3D G3DSA:3.40.50.1370 135 292 7.8E-124 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L01_07925 74353b71f8b5193be6b9a46c722950b3 308 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 51 58 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L01_07925 74353b71f8b5193be6b9a46c722950b3 308 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 5 307 39.815 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L01_07925 74353b71f8b5193be6b9a46c722950b3 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 293 4.1E-24 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L01_07925 74353b71f8b5193be6b9a46c722950b3 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 51 70 4.1E-24 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L01_07925 74353b71f8b5193be6b9a46c722950b3 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 4.1E-24 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L01_07925 74353b71f8b5193be6b9a46c722950b3 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 4.1E-24 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L01_07925 74353b71f8b5193be6b9a46c722950b3 308 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 302 2.9E-29 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A3L01_07925 74353b71f8b5193be6b9a46c722950b3 308 Gene3D G3DSA:3.40.50.1370 7 301 7.8E-124 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L01_07925 74353b71f8b5193be6b9a46c722950b3 308 SUPERFAMILY SSF53671 2 306 2.49E-102 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L01_02395 9148f5f4cec185d33774db0298d392a8 206 SUPERFAMILY SSF109604 14 205 2.01E-61 T 23-10-2018 A3L01_02395 9148f5f4cec185d33774db0298d392a8 206 SMART SM00471 30 147 1.4E-11 T 23-10-2018 IPR003607 HD/PDEase domain A3L01_02395 9148f5f4cec185d33774db0298d392a8 206 Pfam PF01966 HD domain 35 137 1.9E-20 T 23-10-2018 IPR006674 HD domain A3L01_02395 9148f5f4cec185d33774db0298d392a8 206 TIGRFAM TIGR00277 HDIG: HDIG domain 34 96 3.3E-9 T 23-10-2018 IPR006675 HDIG domain A3L01_02395 9148f5f4cec185d33774db0298d392a8 206 Gene3D G3DSA:1.10.3210.50 14 206 3.2E-64 T 23-10-2018 A3L01_03565 67df6615efd6c42e0adb0b074906e49e 333 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 8 318 4.0E-32 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A3L01_03565 67df6615efd6c42e0adb0b074906e49e 333 Gene3D G3DSA:3.40.50.720 95 286 4.9E-110 T 23-10-2018 A3L01_03565 67df6615efd6c42e0adb0b074906e49e 333 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A3L01_03565 67df6615efd6c42e0adb0b074906e49e 333 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 286 4.0E-53 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A3L01_03565 67df6615efd6c42e0adb0b074906e49e 333 Gene3D G3DSA:3.40.50.720 16 318 4.9E-110 T 23-10-2018 A3L01_03565 67df6615efd6c42e0adb0b074906e49e 333 SUPERFAMILY SSF51735 100 287 2.26E-50 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_03565 67df6615efd6c42e0adb0b074906e49e 333 SUPERFAMILY SSF52283 1 132 1.11E-32 T 23-10-2018 A3L01_02105 56a8518c233aeb3509d0a7c3761520ad 361 SUPERFAMILY SSF51161 200 355 1.08E-24 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A3L01_02105 56a8518c233aeb3509d0a7c3761520ad 361 Pfam PF00483 Nucleotidyl transferase 2 231 6.8E-52 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L01_02105 56a8518c233aeb3509d0a7c3761520ad 361 Gene3D G3DSA:3.90.550.10 1 238 2.9E-78 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_02105 56a8518c233aeb3509d0a7c3761520ad 361 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 308 341 3.7E-8 T 23-10-2018 IPR001451 Hexapeptide repeat A3L01_02105 56a8518c233aeb3509d0a7c3761520ad 361 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 258 293 2.4E-6 T 23-10-2018 IPR001451 Hexapeptide repeat A3L01_02105 56a8518c233aeb3509d0a7c3761520ad 361 Gene3D G3DSA:2.160.10.10 267 361 2.2E-19 T 23-10-2018 A3L01_02105 56a8518c233aeb3509d0a7c3761520ad 361 SUPERFAMILY SSF53448 1 320 7.58E-81 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_00445 9d2179baed08caf28afe7dc96e6c4acc 220 Pfam PF04256 Protein of unknown function (DUF434) 2 56 2.0E-21 T 23-10-2018 IPR007368 Protein of unknown function DUF434 A3L01_00445 9d2179baed08caf28afe7dc96e6c4acc 220 ProDom PD019177 PF1672 MJ0935 ST1363 PH1730 UNCHARACTERIZED ARCHAEAL 2 54 8.0E-16 T 23-10-2018 IPR007368 Protein of unknown function DUF434 A3L01_08810 65637deb11449cef2acc837dbbf699da 170 SUPERFAMILY SSF47240 14 157 2.35E-20 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L01_08810 65637deb11449cef2acc837dbbf699da 170 Pfam PF02915 Rubrerythrin 105 161 1.0E-7 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L01_08810 65637deb11449cef2acc837dbbf699da 170 Gene3D G3DSA:1.20.1260.10 8 156 1.1E-22 T 23-10-2018 IPR012347 Ferritin-like A3L01_09850 2bf2ff59f4dd4a6ad2cea7e1701f7b7b 463 TIGRFAM TIGR01041 ATP_syn_B_arch: ATP synthase archaeal, B subunit 5 461 6.6E-267 T 23-10-2018 IPR005724 ATPase, A1 complex, beta subunit GO:0015986|GO:0033178|GO:0046933 A3L01_09850 2bf2ff59f4dd4a6ad2cea7e1701f7b7b 463 SUPERFAMILY SSF47917 362 420 1.99E-9 T 23-10-2018 A3L01_09850 2bf2ff59f4dd4a6ad2cea7e1701f7b7b 463 PIRSF PIRSF039114 1 463 5.0E-256 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L01_09850 2bf2ff59f4dd4a6ad2cea7e1701f7b7b 463 Gene3D G3DSA:3.40.50.12240 2 459 5.0E-196 T 23-10-2018 A3L01_09850 2bf2ff59f4dd4a6ad2cea7e1701f7b7b 463 SUPERFAMILY SSF52540 79 355 5.31E-89 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_09850 2bf2ff59f4dd4a6ad2cea7e1701f7b7b 463 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 132 350 7.6E-69 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L01_09850 2bf2ff59f4dd4a6ad2cea7e1701f7b7b 463 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 341 350 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L01_09850 2bf2ff59f4dd4a6ad2cea7e1701f7b7b 463 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 3 459 62.463 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L01_09850 2bf2ff59f4dd4a6ad2cea7e1701f7b7b 463 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 9 75 9.7E-14 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L01_09850 2bf2ff59f4dd4a6ad2cea7e1701f7b7b 463 SUPERFAMILY SSF50615 5 67 7.06E-5 T 23-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L01_06655 9c70107812b57cdae7ad7e7724fe4ebe 216 Pfam PF01863 Protein of unknown function DUF45 11 197 2.4E-48 T 23-10-2018 IPR002725 Protein of unknown function DUF45 A3L01_06655 9c70107812b57cdae7ad7e7724fe4ebe 216 Gene3D G3DSA:3.30.2010.10 107 201 2.0E-20 T 23-10-2018 A3L01_04510 a0d877f3b30e89d22002197b00040d59 633 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 220 622 3.0E-126 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L01_04510 a0d877f3b30e89d22002197b00040d59 633 SMART SM00790 7 207 1.8E-109 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L01_04510 a0d877f3b30e89d22002197b00040d59 633 Gene3D G3DSA:1.10.599.10 239 622 4.6E-131 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A3L01_04510 a0d877f3b30e89d22002197b00040d59 633 Gene3D G3DSA:1.10.569.10 241 444 4.6E-131 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L01_04510 a0d877f3b30e89d22002197b00040d59 633 SUPERFAMILY SSF48310 214 629 2.62E-118 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L01_04510 a0d877f3b30e89d22002197b00040d59 633 Gene3D G3DSA:3.60.9.10 5 211 2.5E-75 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L01_04510 a0d877f3b30e89d22002197b00040d59 633 SUPERFAMILY SSF56228 6 209 1.57E-65 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L01_04510 a0d877f3b30e89d22002197b00040d59 633 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 9 206 3.9E-70 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L01_00140 e337733e9f1e042474ad80ec3eda84f5 188 Pfam PF00117 Glutamine amidotransferase class-I 4 181 2.4E-45 T 23-10-2018 IPR017926 Glutamine amidotransferase A3L01_00140 e337733e9f1e042474ad80ec3eda84f5 188 Gene3D G3DSA:3.40.50.880 1 187 2.5E-61 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_00140 e337733e9f1e042474ad80ec3eda84f5 188 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 2 186 3.7E-81 T 23-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A3L01_00140 e337733e9f1e042474ad80ec3eda84f5 188 PRINTS PR00097 Anthranilate synthase component II signature 161 174 2.5E-11 T 23-10-2018 A3L01_00140 e337733e9f1e042474ad80ec3eda84f5 188 PRINTS PR00097 Anthranilate synthase component II signature 46 55 2.5E-11 T 23-10-2018 A3L01_00140 e337733e9f1e042474ad80ec3eda84f5 188 PRINTS PR00097 Anthranilate synthase component II signature 2 16 2.5E-11 T 23-10-2018 A3L01_00140 e337733e9f1e042474ad80ec3eda84f5 188 PRINTS PR00097 Anthranilate synthase component II signature 73 84 2.5E-11 T 23-10-2018 A3L01_00140 e337733e9f1e042474ad80ec3eda84f5 188 SUPERFAMILY SSF52317 1 186 5.66E-56 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_00140 e337733e9f1e042474ad80ec3eda84f5 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 1.8E-9 T 23-10-2018 A3L01_00140 e337733e9f1e042474ad80ec3eda84f5 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 161 174 1.8E-9 T 23-10-2018 A3L01_00140 e337733e9f1e042474ad80ec3eda84f5 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 73 84 1.8E-9 T 23-10-2018 A3L01_00140 e337733e9f1e042474ad80ec3eda84f5 188 Hamap MF_01510 GMP synthase [glutamine-hydrolyzing] subunit A [guaAA]. 1 187 44.954 T 23-10-2018 IPR023686 GMP synthase (glutamine-hydrolyzing) subunit A GO:0003922 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 A3L01_00140 e337733e9f1e042474ad80ec3eda84f5 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 73 89 1.0E-5 T 23-10-2018 A3L01_00140 e337733e9f1e042474ad80ec3eda84f5 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 1.0E-5 T 23-10-2018 A3L01_05710 fc0d107ce0d25ce74096d1c9a30ec8d8 199 SUPERFAMILY SSF50475 4 190 1.49E-27 T 23-10-2018 A3L01_05710 fc0d107ce0d25ce74096d1c9a30ec8d8 199 PIRSF PIRSF018747 1 192 2.7E-43 T 23-10-2018 IPR016733 Uncharacterised conserved protein UCP018747 A3L01_05710 fc0d107ce0d25ce74096d1c9a30ec8d8 199 Gene3D G3DSA:2.30.110.10 10 128 4.4E-7 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A3L01_05710 fc0d107ce0d25ce74096d1c9a30ec8d8 199 Pfam PF04289 Protein of unknown function (DUF447) 11 184 6.1E-22 T 23-10-2018 IPR007386 Protein of unknown function DUF447 A3L01_05710 fc0d107ce0d25ce74096d1c9a30ec8d8 199 Gene3D G3DSA:1.20.58.290 58 182 4.4E-7 T 23-10-2018 A3L01_08220 69cc2a8d85f7dce2914d91d7289c5bf3 174 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 80 91 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_08220 69cc2a8d85f7dce2914d91d7289c5bf3 174 SUPERFAMILY SSF54862 1 149 7.03E-51 T 23-10-2018 A3L01_08220 69cc2a8d85f7dce2914d91d7289c5bf3 174 Pfam PF13247 4Fe-4S dicluster domain 42 134 1.7E-25 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_08220 69cc2a8d85f7dce2914d91d7289c5bf3 174 Gene3D G3DSA:3.30.70.20 32 172 8.4E-40 T 23-10-2018 A3L01_02145 8a7268f0bd40f405761e1bb4e4ba39b5 156 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 9 152 4.7E-45 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 A3L01_02145 8a7268f0bd40f405761e1bb4e4ba39b5 156 Pfam PF00692 dUTPase 43 139 2.8E-12 T 23-10-2018 IPR029054 dUTPase-like A3L01_02145 8a7268f0bd40f405761e1bb4e4ba39b5 156 Gene3D G3DSA:2.70.40.10 1 155 7.3E-42 T 23-10-2018 IPR036157 dUTPase-like superfamily A3L01_02145 8a7268f0bd40f405761e1bb4e4ba39b5 156 Hamap MF_00146 dCTP deaminase [dcd]. 1 153 27.357 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 A3L01_02145 8a7268f0bd40f405761e1bb4e4ba39b5 156 SUPERFAMILY SSF51283 1 152 1.02E-38 T 23-10-2018 IPR036157 dUTPase-like superfamily A3L01_04420 3828128a0681ae137aa66be386a8a5b0 899 Pfam PF00270 DEAD/DEAH box helicase 50 227 7.7E-22 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L01_04420 3828128a0681ae137aa66be386a8a5b0 899 Gene3D G3DSA:3.40.50.300 254 408 1.1E-22 T 23-10-2018 A3L01_04420 3828128a0681ae137aa66be386a8a5b0 899 SUPERFAMILY SSF52540 57 378 3.72E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_04420 3828128a0681ae137aa66be386a8a5b0 899 SMART SM00487 44 253 1.6E-26 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L01_04420 3828128a0681ae137aa66be386a8a5b0 899 SMART SM00490 292 376 5.6E-18 T 23-10-2018 IPR001650 Helicase, C-terminal A3L01_04420 3828128a0681ae137aa66be386a8a5b0 899 Pfam PF09369 Domain of unknown function (DUF1998) 782 863 1.7E-16 T 23-10-2018 IPR018973 DEAD/DEAH-box helicase, putative A3L01_04420 3828128a0681ae137aa66be386a8a5b0 899 Gene3D G3DSA:3.40.50.300 31 241 4.6E-40 T 23-10-2018 A3L01_04420 3828128a0681ae137aa66be386a8a5b0 899 Pfam PF00271 Helicase conserved C-terminal domain 274 375 6.6E-17 T 23-10-2018 IPR001650 Helicase, C-terminal A3L01_10150 6dc7ece9301cc636d33d35b2dd6a8c38 184 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 182 27.152 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A3L01_10150 6dc7ece9301cc636d33d35b2dd6a8c38 184 Pfam PF02834 LigT like Phosphoesterase 7 91 8.1E-20 T 23-10-2018 IPR014051 Phosphoesterase, HXTX A3L01_10150 6dc7ece9301cc636d33d35b2dd6a8c38 184 Pfam PF02834 LigT like Phosphoesterase 98 174 1.1E-13 T 23-10-2018 IPR014051 Phosphoesterase, HXTX A3L01_10150 6dc7ece9301cc636d33d35b2dd6a8c38 184 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 182 7.5E-55 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A3L01_10150 6dc7ece9301cc636d33d35b2dd6a8c38 184 SUPERFAMILY SSF55144 1 182 2.27E-45 T 23-10-2018 IPR009097 Cyclic phosphodiesterase A3L01_10150 6dc7ece9301cc636d33d35b2dd6a8c38 184 Gene3D G3DSA:3.90.1140.10 1 184 3.8E-67 T 23-10-2018 A3L01_10085 bbb75de7c7fa7e8a2fecf28f1006b7e2 644 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 109 193 6.0E-7 T 23-10-2018 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 A3L01_10085 bbb75de7c7fa7e8a2fecf28f1006b7e2 644 SUPERFAMILY SSF81296 24 84 9.24E-12 T 23-10-2018 IPR014756 Immunoglobulin E-set A3L01_10085 bbb75de7c7fa7e8a2fecf28f1006b7e2 644 Gene3D G3DSA:2.60.40.1180 582 637 2.1E-7 T 23-10-2018 IPR013780 Glycosyl hydrolase, all-beta A3L01_10085 bbb75de7c7fa7e8a2fecf28f1006b7e2 644 Pfam PF00128 Alpha amylase, catalytic domain 236 543 1.5E-62 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L01_10085 bbb75de7c7fa7e8a2fecf28f1006b7e2 644 Gene3D G3DSA:2.60.40.10 104 196 5.3E-22 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_10085 bbb75de7c7fa7e8a2fecf28f1006b7e2 644 Gene3D G3DSA:3.20.20.80 197 581 2.8E-148 T 23-10-2018 A3L01_10085 bbb75de7c7fa7e8a2fecf28f1006b7e2 644 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 20 83 1.0E-8 T 23-10-2018 IPR032640 AMP-activated protein kinase, glycogen-binding domain Reactome: R-HSA-1445148|Reactome: R-HSA-1632852|Reactome: R-HSA-2151209|Reactome: R-HSA-380972|Reactome: R-HSA-5628897|Reactome: R-HSA-6804756 A3L01_10085 bbb75de7c7fa7e8a2fecf28f1006b7e2 644 Gene3D G3DSA:2.60.40.10 1 103 1.3E-20 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_10085 bbb75de7c7fa7e8a2fecf28f1006b7e2 644 SUPERFAMILY SSF51011 585 642 4.56E-9 T 23-10-2018 A3L01_10085 bbb75de7c7fa7e8a2fecf28f1006b7e2 644 SUPERFAMILY SSF51445 194 585 2.5E-98 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L01_10085 bbb75de7c7fa7e8a2fecf28f1006b7e2 644 SMART SM00642 209 576 2.6E-102 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L01_10085 bbb75de7c7fa7e8a2fecf28f1006b7e2 644 SUPERFAMILY SSF81296 108 202 1.87E-10 T 23-10-2018 IPR014756 Immunoglobulin E-set A3L01_07095 c6193b9ac29b37cfe450fb9c7132e310 76 Pfam PF13244 Domain of unknown function (DUF4040) 12 72 1.1E-10 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A3L01_03270 0e0105de25cd509c328cef8b4ce83cc1 415 Gene3D G3DSA:3.30.1330.30 274 415 2.4E-42 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L01_03270 0e0105de25cd509c328cef8b4ce83cc1 415 TIGRFAM TIGR03676 aRF1/eRF1: peptide chain release factor 1, archaeal and eukaryotic forms 7 414 2.6E-182 T 23-10-2018 IPR004403 Peptide chain release factor eRF1/aRF1 GO:0003747|GO:0005737|GO:0006415 Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_03270 0e0105de25cd509c328cef8b4ce83cc1 415 SMART SM01194 1 135 4.5E-34 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A3L01_03270 0e0105de25cd509c328cef8b4ce83cc1 415 Pfam PF03464 eRF1 domain 2 140 272 6.4E-50 T 23-10-2018 IPR005141 eRF1 domain 2 A3L01_03270 0e0105de25cd509c328cef8b4ce83cc1 415 Pfam PF03463 eRF1 domain 1 17 133 6.2E-9 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A3L01_03270 0e0105de25cd509c328cef8b4ce83cc1 415 Pfam PF03465 eRF1 domain 3 276 414 8.4E-34 T 23-10-2018 IPR005142 eRF1 domain 3 A3L01_03270 0e0105de25cd509c328cef8b4ce83cc1 415 Hamap MF_00424 Peptide chain release factor subunit 1 [prf1]. 18 415 45.569 T 23-10-2018 IPR020918 Peptide chain release factor aRF1 GO:0003747|GO:0005737|GO:0006415 A3L01_03270 0e0105de25cd509c328cef8b4ce83cc1 415 SUPERFAMILY SSF53137 138 271 6.54E-44 T 23-10-2018 A3L01_03270 0e0105de25cd509c328cef8b4ce83cc1 415 Gene3D G3DSA:3.30.960.10 1 130 2.2E-54 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_03270 0e0105de25cd509c328cef8b4ce83cc1 415 SUPERFAMILY SSF55481 3 135 9.68E-49 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_03270 0e0105de25cd509c328cef8b4ce83cc1 415 Gene3D G3DSA:3.30.420.60 131 271 4.7E-54 T 23-10-2018 A3L01_03270 0e0105de25cd509c328cef8b4ce83cc1 415 SUPERFAMILY SSF55315 272 414 4.59E-39 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L01_02130 bc28f70d732e149dd3a438333ba88e3e 133 SMART SM00493 20 90 3.0E-8 T 23-10-2018 IPR006171 TOPRIM domain A3L01_02130 bc28f70d732e149dd3a438333ba88e3e 133 Hamap MF_01095 UPF0292 protein . 3 123 32.984 T 23-10-2018 IPR022972 Uncharacterised protein family UPF0292 A3L01_02130 bc28f70d732e149dd3a438333ba88e3e 133 Pfam PF01751 Toprim domain 25 86 1.3E-5 T 23-10-2018 IPR006171 TOPRIM domain A3L01_02130 bc28f70d732e149dd3a438333ba88e3e 133 Gene3D G3DSA:3.40.1360.10 3 117 4.1E-22 T 23-10-2018 A3L01_02130 bc28f70d732e149dd3a438333ba88e3e 133 SUPERFAMILY SSF110455 19 90 3.66E-6 T 23-10-2018 A3L01_06685 f980fc7d85163d600b90914b84c14423 277 Gene3D G3DSA:1.10.3720.10 2 270 1.1E-51 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_06685 f980fc7d85163d600b90914b84c14423 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 268 1.8E-21 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_06685 f980fc7d85163d600b90914b84c14423 277 SUPERFAMILY SSF161098 10 269 5.51E-54 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_08455 1c68a06ab2063c1f90439720a3ace8de 195 Pfam PF03167 Uracil DNA glycosylase superfamily 31 184 9.9E-48 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L01_08455 1c68a06ab2063c1f90439720a3ace8de 195 SMART SM00987 31 185 1.2E-37 T 23-10-2018 A3L01_08455 1c68a06ab2063c1f90439720a3ace8de 195 Gene3D G3DSA:3.40.470.10 5 192 2.2E-72 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L01_08455 1c68a06ab2063c1f90439720a3ace8de 195 SMART SM00986 31 185 1.2E-37 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L01_08455 1c68a06ab2063c1f90439720a3ace8de 195 SUPERFAMILY SSF52141 7 192 9.81E-63 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L01_08455 1c68a06ab2063c1f90439720a3ace8de 195 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 17 191 9.7E-77 T 23-10-2018 IPR005273 Uracil-DNA glycosylase family 4 A3L01_02055 982560b638de60858cb51f9fd49e3976 250 Gene3D G3DSA:3.20.20.190 3 250 9.7E-95 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A3L01_02055 982560b638de60858cb51f9fd49e3976 250 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 14 235 2.1E-29 T 23-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A3L01_02055 982560b638de60858cb51f9fd49e3976 250 SUPERFAMILY SSF51695 8 244 2.24E-55 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A3L01_07890 35cbc2b6175da293ce3f527200c9bdb2 151 Gene3D G3DSA:3.30.54.20 77 119 1.1E-23 T 23-10-2018 A3L01_07890 35cbc2b6175da293ce3f527200c9bdb2 151 Gene3D G3DSA:3.30.980.10 2 76 3.8E-33 T 23-10-2018 A3L01_07890 35cbc2b6175da293ce3f527200c9bdb2 151 SUPERFAMILY SSF55186 5 148 1.07E-38 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A3L01_09955 5c78fe8e7753bfcc7ded6558b38c3ee6 135 Hamap MF_00585 UPF0216 protein . 4 135 27.156 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A3L01_09955 5c78fe8e7753bfcc7ded6558b38c3ee6 135 PIRSF PIRSF005264 1 135 1.7E-44 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A3L01_09955 5c78fe8e7753bfcc7ded6558b38c3ee6 135 Pfam PF01886 Protein of unknown function DUF61 6 132 9.0E-35 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A3L01_09955 5c78fe8e7753bfcc7ded6558b38c3ee6 135 ProDom PD016056 UPF0216 PYRAB16100 PH0358 MTH949 MK1676 AF0460 PF0452 MJ1224 8 132 5.0E-38 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A3L01_06295 49b75441433f630ebbae4f446156a016 228 PIRSF PIRSF006413 2 228 3.7E-78 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L01_06295 49b75441433f630ebbae4f446156a016 228 Hamap MF_00032 Translation initiation factor 6 [eif6]. 1 228 95.896 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L01_06295 49b75441433f630ebbae4f446156a016 228 SUPERFAMILY SSF55909 3 226 5.69E-74 T 23-10-2018 A3L01_06295 49b75441433f630ebbae4f446156a016 228 TIGRFAM TIGR00323 eIF-6: putative translation initiation factor eIF-6 5 226 1.8E-64 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L01_06295 49b75441433f630ebbae4f446156a016 228 Gene3D G3DSA:3.75.10.10 1 227 4.0E-78 T 23-10-2018 A3L01_06295 49b75441433f630ebbae4f446156a016 228 Pfam PF01912 eIF-6 family 5 205 2.8E-68 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L01_06295 49b75441433f630ebbae4f446156a016 228 SMART SM00654 4 206 1.3E-105 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 Gene3D G3DSA:3.10.28.10 521 694 1.0E-17 T 23-10-2018 IPR027434 Homing endonuclease A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 SUPERFAMILY SSF57783 1141 1184 2.72E-5 T 23-10-2018 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 805 827 4.6E-10 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 SUPERFAMILY SSF56712 2 316 7.46E-83 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 Pfam PF14528 LAGLIDADG-like domain 618 699 2.7E-11 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 SMART SM00437 271 1038 2.8E-99 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 1146 1183 4.1E-13 T 23-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 316 387 2.7E-6 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 Pfam PF01131 DNA topoisomerase 827 1075 1.0E-73 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 Pfam PF01131 DNA topoisomerase 156 315 2.7E-50 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 SMART SM00436 131 226 3.4E-44 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 PRINTS PR00379 Intein signature 821 830 9.8E-14 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 PRINTS PR00379 Intein signature 803 820 9.8E-14 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 PRINTS PR00379 Intein signature 525 537 9.8E-14 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 PRINTS PR00379 Intein signature 619 631 9.8E-14 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 PRINTS PR00379 Intein signature 374 387 9.8E-14 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 Gene3D G3DSA:2.60.510.20 915 984 1.4E-54 T 23-10-2018 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 Gene3D G3DSA:2.60.510.20 218 280 1.3E-36 T 23-10-2018 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 SUPERFAMILY SSF55608 521 605 4.89E-10 T 23-10-2018 IPR027434 Homing endonuclease A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 SMART SM00305 786 832 1.7E-18 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 Pfam PF14890 Intein splicing domain 327 826 3.7E-29 T 23-10-2018 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 TIGRFAM TIGR01057 topA_arch: DNA topoisomerase I 6 319 9.7E-148 T 23-10-2018 IPR005739 DNA topoisomerase I, archeal-type GO:0003677|GO:0003916|GO:0006265 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 Gene3D G3DSA:2.170.16.10 707 825 1.6E-14 T 23-10-2018 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 Pfam PF01751 Toprim domain 3 139 8.5E-18 T 23-10-2018 IPR006171 TOPRIM domain A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 Gene3D G3DSA:1.10.460.10 985 1077 1.4E-54 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 Gene3D G3DSA:1.10.460.10 161 217 1.3E-36 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 SUPERFAMILY SSF55608 606 716 1.51E-12 T 23-10-2018 IPR027434 Homing endonuclease A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 SUPERFAMILY SSF51294 316 826 4.12E-38 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 SMART SM00493 2 129 1.4E-19 T 23-10-2018 IPR006171 TOPRIM domain A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 Hamap MF_00952 DNA topoisomerase 1 [topA]. 2 1215 43.957 T 23-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 Gene3D G3DSA:2.170.16.10 316 431 1.1E-10 T 23-10-2018 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 103 116 2.1E-22 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1002 1016 2.1E-22 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 196 214 2.1E-22 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 903 919 2.1E-22 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 SUPERFAMILY SSF56712 827 1158 7.19E-73 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 Gene3D G3DSA:1.10.290.10 828 914 1.4E-54 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 Gene3D G3DSA:1.10.290.10 281 315 1.3E-36 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 SMART SM00306 314 411 8.7E-21 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L01_02240 369b76bc054ae4460a44a36773c1fcd9 1226 Gene3D G3DSA:3.40.50.140 1 154 3.8E-30 T 23-10-2018 A3L01_10060 d388f3f8d64f560d3552135b21ccd9b4 372 Gene3D G3DSA:3.40.50.300 1 243 1.1E-75 T 23-10-2018 A3L01_10060 d388f3f8d64f560d3552135b21ccd9b4 372 Gene3D G3DSA:2.40.50.100 245 304 5.1E-24 T 23-10-2018 A3L01_10060 d388f3f8d64f560d3552135b21ccd9b4 372 SUPERFAMILY SSF52540 4 249 4.76E-89 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_10060 d388f3f8d64f560d3552135b21ccd9b4 372 Pfam PF00005 ABC transporter 20 167 6.3E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_10060 d388f3f8d64f560d3552135b21ccd9b4 372 Gene3D G3DSA:2.40.50.140 310 354 2.0E-26 T 23-10-2018 A3L01_10060 d388f3f8d64f560d3552135b21ccd9b4 372 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_10060 d388f3f8d64f560d3552135b21ccd9b4 372 SMART SM00382 28 217 1.8E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_10060 d388f3f8d64f560d3552135b21ccd9b4 372 Pfam PF08402 TOBE domain 288 363 2.7E-7 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A3L01_10060 d388f3f8d64f560d3552135b21ccd9b4 372 SUPERFAMILY SSF50331 242 371 5.35E-25 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L01_05380 a30a18a11ddc5afc507cb0a182d8e7a8 761 Pfam PF13181 Tetratricopeptide repeat 588 617 0.0011 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L01_05380 a30a18a11ddc5afc507cb0a182d8e7a8 761 SUPERFAMILY SSF48452 585 708 4.74E-13 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_05380 a30a18a11ddc5afc507cb0a182d8e7a8 761 SMART SM00418 7 90 1.6E-11 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_05380 a30a18a11ddc5afc507cb0a182d8e7a8 761 SUPERFAMILY SSF48452 456 614 2.43E-9 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_05380 a30a18a11ddc5afc507cb0a182d8e7a8 761 Gene3D G3DSA:1.25.40.10 564 746 2.7E-17 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_05380 a30a18a11ddc5afc507cb0a182d8e7a8 761 Gene3D G3DSA:1.10.10.10 4 96 1.4E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_05380 a30a18a11ddc5afc507cb0a182d8e7a8 761 SUPERFAMILY SSF46785 4 88 2.69E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_05380 a30a18a11ddc5afc507cb0a182d8e7a8 761 Gene3D G3DSA:1.25.40.10 454 563 1.2E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_05380 a30a18a11ddc5afc507cb0a182d8e7a8 761 Pfam PF12840 Helix-turn-helix domain 8 62 2.0E-9 T 23-10-2018 A3L01_05380 a30a18a11ddc5afc507cb0a182d8e7a8 761 Gene3D G3DSA:3.40.50.300 105 244 1.3E-6 T 23-10-2018 A3L01_05380 a30a18a11ddc5afc507cb0a182d8e7a8 761 SUPERFAMILY SSF52540 109 339 8.54E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_05380 a30a18a11ddc5afc507cb0a182d8e7a8 761 SMART SM00028 504 537 79.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L01_05380 a30a18a11ddc5afc507cb0a182d8e7a8 761 SMART SM00028 585 618 0.45 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L01_05380 a30a18a11ddc5afc507cb0a182d8e7a8 761 SMART SM00028 468 501 300.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L01_05380 a30a18a11ddc5afc507cb0a182d8e7a8 761 SMART SM00028 625 658 85.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L01_02135 1e0139d73d178dbd2043a7607fdcec1f 424 Pfam PF02310 B12 binding domain 18 112 5.6E-9 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A3L01_02135 1e0139d73d178dbd2043a7607fdcec1f 424 SUPERFAMILY SSF102114 155 376 3.4E-39 T 23-10-2018 A3L01_02135 1e0139d73d178dbd2043a7607fdcec1f 424 TIGRFAM TIGR04013 B12_SAM_MJ_1487: B12-binding domain/radical SAM domain protein, MJ_1487 family 4 392 3.3E-141 T 23-10-2018 IPR023980 Conserved hypothetical protein CHP04013, B12-binding/radical SAM-type A3L01_02135 1e0139d73d178dbd2043a7607fdcec1f 424 Gene3D G3DSA:3.80.30.20 163 391 1.6E-37 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L01_02135 1e0139d73d178dbd2043a7607fdcec1f 424 Pfam PF04055 Radical SAM superfamily 168 338 1.5E-24 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L01_02135 1e0139d73d178dbd2043a7607fdcec1f 424 SMART SM00729 164 382 6.9E-48 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L01_02135 1e0139d73d178dbd2043a7607fdcec1f 424 Gene3D G3DSA:3.40.50.280 3 127 1.5E-24 T 23-10-2018 A3L01_08565 3974048aa2f3063d2ac6db430848c375 183 PIRSF PIRSF006006 1 178 1.5E-85 T 23-10-2018 IPR007501 Protein of unknown function DUF531 A3L01_08565 3974048aa2f3063d2ac6db430848c375 183 Pfam PF04407 Protein of unknown function (DUF531) 1 169 2.5E-78 T 23-10-2018 IPR007501 Protein of unknown function DUF531 A3L01_02160 d9b52a3d1b104d2e9364876d705f291f 105 Gene3D G3DSA:1.10.10.1410 1 58 4.4E-31 T 23-10-2018 IPR038716 Ribosomal protein P1/P2, N-terminal domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_02160 d9b52a3d1b104d2e9364876d705f291f 105 TIGRFAM TIGR03685 ribo_P1_arch: 50S ribosomal protein P1 1 105 1.9E-42 T 23-10-2018 IPR022295 Ribosomal protein L12, archaea GO:0003735|GO:0005840|GO:0006414 A3L01_02160 d9b52a3d1b104d2e9364876d705f291f 105 Pfam PF00428 60s Acidic ribosomal protein 16 104 1.6E-19 T 23-10-2018 A3L01_02160 d9b52a3d1b104d2e9364876d705f291f 105 Hamap MF_01478 50S ribosomal protein L12 [rpl12]. 1 102 14.584 T 23-10-2018 IPR027534 Ribosomal protein L12 family GO:0003735|GO:0005622|GO:0005840|GO:0006414 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_04150 8b279278ec1aee405e8e5f7b754cdc02 370 PIRSF PIRSF018978 1 370 1.6E-182 T 23-10-2018 IPR016742 tRNA methyltransferase, archaea GO:0008175|GO:0030488 A3L01_04150 8b279278ec1aee405e8e5f7b754cdc02 370 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 168 215 3.1E-5 T 23-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 A3L01_04150 8b279278ec1aee405e8e5f7b754cdc02 370 Gene3D G3DSA:3.40.1280.30 90 231 5.6E-7 T 23-10-2018 IPR038459 tRNA methyltransferase TRM10-type domain superfamily A3L01_07395 f9f970834f1ff2bb9eff59e6bb97a166 265 SUPERFAMILY SSF102588 40 253 3.4E-53 T 23-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A3L01_07395 f9f970834f1ff2bb9eff59e6bb97a166 265 Gene3D G3DSA:3.40.50.10320 13 265 4.0E-83 T 23-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A3L01_07395 f9f970834f1ff2bb9eff59e6bb97a166 265 Pfam PF02585 GlcNAc-PI de-N-acetylase 42 166 1.3E-27 T 23-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A3L01_04780 1f9b912865aba6a63825bd743456bba2 405 Gene3D G3DSA:3.40.50.1950 16 186 6.3E-47 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A3L01_04780 1f9b912865aba6a63825bd743456bba2 405 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 18 399 1.6E-128 T 23-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 A3L01_04780 1f9b912865aba6a63825bd743456bba2 405 SUPERFAMILY SSF52507 18 217 3.53E-47 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A3L01_04780 1f9b912865aba6a63825bd743456bba2 405 Gene3D G3DSA:3.40.50.10300 187 405 1.5E-72 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A3L01_04780 1f9b912865aba6a63825bd743456bba2 405 Pfam PF02441 Flavoprotein 19 188 8.1E-41 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A3L01_04780 1f9b912865aba6a63825bd743456bba2 405 SUPERFAMILY SSF102645 180 404 2.75E-66 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A3L01_04780 1f9b912865aba6a63825bd743456bba2 405 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 193 374 3.9E-57 T 23-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A3L01_01625 42c68a67ccb42be6461be1b0c5dc2b25 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 1.4E-29 T 23-10-2018 A3L01_01625 42c68a67ccb42be6461be1b0c5dc2b25 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 1.4E-29 T 23-10-2018 A3L01_01625 42c68a67ccb42be6461be1b0c5dc2b25 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.4E-29 T 23-10-2018 A3L01_01625 42c68a67ccb42be6461be1b0c5dc2b25 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 1.4E-29 T 23-10-2018 A3L01_01625 42c68a67ccb42be6461be1b0c5dc2b25 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 1.4E-29 T 23-10-2018 A3L01_01625 42c68a67ccb42be6461be1b0c5dc2b25 441 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 326 427 1.3E-17 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A3L01_01625 42c68a67ccb42be6461be1b0c5dc2b25 441 Gene3D G3DSA:3.50.50.60 43 241 7.2E-114 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_01625 42c68a67ccb42be6461be1b0c5dc2b25 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 9.7E-23 T 23-10-2018 A3L01_01625 42c68a67ccb42be6461be1b0c5dc2b25 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 174 9.7E-23 T 23-10-2018 A3L01_01625 42c68a67ccb42be6461be1b0c5dc2b25 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 384 399 9.7E-23 T 23-10-2018 A3L01_01625 42c68a67ccb42be6461be1b0c5dc2b25 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 281 9.7E-23 T 23-10-2018 A3L01_01625 42c68a67ccb42be6461be1b0c5dc2b25 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 247 9.7E-23 T 23-10-2018 A3L01_01625 42c68a67ccb42be6461be1b0c5dc2b25 441 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 303 1.8E-60 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L01_01625 42c68a67ccb42be6461be1b0c5dc2b25 441 SUPERFAMILY SSF51905 5 344 9.77E-48 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_01625 42c68a67ccb42be6461be1b0c5dc2b25 441 TIGRFAM TIGR03385 CoA_CoA_reduc: CoA-disulfide reductase 5 436 1.0E-176 T 23-10-2018 IPR017758 Coenzyme A disulphide reductase GO:0003756|GO:0050451|GO:0050660|GO:0050661|GO:0055114 A3L01_01625 42c68a67ccb42be6461be1b0c5dc2b25 441 Gene3D G3DSA:3.50.50.60 320 441 1.4E-43 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_01625 42c68a67ccb42be6461be1b0c5dc2b25 441 Gene3D G3DSA:3.50.50.60 5 314 7.2E-114 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_01625 42c68a67ccb42be6461be1b0c5dc2b25 441 SUPERFAMILY SSF55424 320 438 2.06E-29 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A3L01_09130 8e464ca42c996336794dae31ab04de47 183 Pfam PF01661 Macro domain 20 145 3.2E-34 T 23-10-2018 IPR002589 Macro domain A3L01_09130 8e464ca42c996336794dae31ab04de47 183 SMART SM00506 3 146 3.9E-52 T 23-10-2018 IPR002589 Macro domain A3L01_09130 8e464ca42c996336794dae31ab04de47 183 Gene3D G3DSA:3.40.220.10 1 181 5.2E-55 T 23-10-2018 A3L01_09130 8e464ca42c996336794dae31ab04de47 183 SUPERFAMILY SSF52949 4 181 3.53E-52 T 23-10-2018 A3L01_03615 9c71e4316d9e1c140ee9125304543bdc 115 SUPERFAMILY SSF55620 1 113 8.89E-33 T 23-10-2018 A3L01_03615 9c71e4316d9e1c140ee9125304543bdc 115 PIRSF PIRSF006113 1 115 1.1E-33 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A3L01_03615 9c71e4316d9e1c140ee9125304543bdc 115 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 5 113 2.6E-28 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A3L01_03615 9c71e4316d9e1c140ee9125304543bdc 115 Gene3D G3DSA:3.30.479.10 1 115 1.6E-39 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 A3L01_00035 c7d13abf1fb9e1bc719135672cdd4379 486 SMART SM01240 13 471 8.2E-261 T 23-10-2018 A3L01_00035 c7d13abf1fb9e1bc719135672cdd4379 486 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 14 453 1.6E-188 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A3L01_00035 c7d13abf1fb9e1bc719135672cdd4379 486 SMART SM00116 102 150 1.2E-9 T 23-10-2018 IPR000644 CBS domain A3L01_00035 c7d13abf1fb9e1bc719135672cdd4379 486 SMART SM00116 160 208 3.3E-10 T 23-10-2018 IPR000644 CBS domain A3L01_00035 c7d13abf1fb9e1bc719135672cdd4379 486 SUPERFAMILY SSF51412 10 475 8.9E-113 T 23-10-2018 A3L01_00035 c7d13abf1fb9e1bc719135672cdd4379 486 Pfam PF00571 CBS domain 153 205 1.9E-15 T 23-10-2018 IPR000644 CBS domain A3L01_00035 c7d13abf1fb9e1bc719135672cdd4379 486 Pfam PF00571 CBS domain 98 146 3.0E-12 T 23-10-2018 IPR000644 CBS domain A3L01_00035 c7d13abf1fb9e1bc719135672cdd4379 486 Gene3D G3DSA:3.20.20.70 4 484 2.0E-197 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_00035 c7d13abf1fb9e1bc719135672cdd4379 486 PIRSF PIRSF000130 3 486 1.2E-193 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A3L01_00035 c7d13abf1fb9e1bc719135672cdd4379 486 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 14 484 79.63 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A3L01_00035 c7d13abf1fb9e1bc719135672cdd4379 486 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 292 304 - T 23-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 A3L01_00035 c7d13abf1fb9e1bc719135672cdd4379 486 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 14 471 7.4E-149 T 23-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A3L01_00035 c7d13abf1fb9e1bc719135672cdd4379 486 SUPERFAMILY SSF54631 71 204 1.53E-32 T 23-10-2018 A3L01_06750 0b4d03c55ac3e5a68c8a008bdbda469a 372 SUPERFAMILY SSF50331 242 371 1.36E-25 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L01_06750 0b4d03c55ac3e5a68c8a008bdbda469a 372 Gene3D G3DSA:3.40.50.300 1 243 4.2E-76 T 23-10-2018 A3L01_06750 0b4d03c55ac3e5a68c8a008bdbda469a 372 SMART SM00382 28 217 1.5E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_06750 0b4d03c55ac3e5a68c8a008bdbda469a 372 SUPERFAMILY SSF52540 4 249 3.22E-89 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06750 0b4d03c55ac3e5a68c8a008bdbda469a 372 Gene3D G3DSA:2.40.50.140 310 354 2.0E-26 T 23-10-2018 A3L01_06750 0b4d03c55ac3e5a68c8a008bdbda469a 372 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_06750 0b4d03c55ac3e5a68c8a008bdbda469a 372 Pfam PF00005 ABC transporter 20 167 1.2E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_06750 0b4d03c55ac3e5a68c8a008bdbda469a 372 Pfam PF08402 TOBE domain 288 363 2.7E-7 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A3L01_06750 0b4d03c55ac3e5a68c8a008bdbda469a 372 Gene3D G3DSA:2.40.50.100 245 304 9.3E-25 T 23-10-2018 A3L01_08090 fdc429181a4fc75ded587c164f063b65 423 PIRSF PIRSF000106 24 417 9.4E-77 T 23-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A3L01_08090 fdc429181a4fc75ded587c164f063b65 423 Pfam PF03949 Malic enzyme, NAD binding domain 158 208 1.4E-6 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A3L01_08090 fdc429181a4fc75ded587c164f063b65 423 Pfam PF03949 Malic enzyme, NAD binding domain 270 375 4.3E-9 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A3L01_08090 fdc429181a4fc75ded587c164f063b65 423 ProSitePatterns PS00331 Malic enzymes signature. 153 169 - T 23-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 A3L01_08090 fdc429181a4fc75ded587c164f063b65 423 SUPERFAMILY SSF51735 157 413 1.03E-62 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_08090 fdc429181a4fc75ded587c164f063b65 423 SMART SM00919 157 387 2.4E-95 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A3L01_08090 fdc429181a4fc75ded587c164f063b65 423 SUPERFAMILY SSF53223 11 155 1.22E-48 T 23-10-2018 A3L01_08090 fdc429181a4fc75ded587c164f063b65 423 Gene3D G3DSA:3.40.50.720 155 423 4.4E-95 T 23-10-2018 A3L01_08090 fdc429181a4fc75ded587c164f063b65 423 SMART SM01274 14 145 3.5E-70 T 23-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A3L01_08090 fdc429181a4fc75ded587c164f063b65 423 Gene3D G3DSA:3.40.50.10380 1 154 6.9E-64 T 23-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 A3L01_08090 fdc429181a4fc75ded587c164f063b65 423 Pfam PF00390 Malic enzyme, N-terminal domain 16 108 1.3E-18 T 23-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A3L01_08775 a377bc836dc2920036838fdbab9c687f 517 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 434 453 7.5E-8 T 23-10-2018 A3L01_08775 a377bc836dc2920036838fdbab9c687f 517 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 86 111 7.5E-8 T 23-10-2018 A3L01_08775 a377bc836dc2920036838fdbab9c687f 517 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 224 245 7.5E-8 T 23-10-2018 A3L01_08775 a377bc836dc2920036838fdbab9c687f 517 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 114 134 7.5E-8 T 23-10-2018 A3L01_08775 a377bc836dc2920036838fdbab9c687f 517 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 318 330 7.5E-8 T 23-10-2018 A3L01_08775 a377bc836dc2920036838fdbab9c687f 517 Pfam PF00361 Proton-conducting membrane transporter 138 441 1.3E-52 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_00070 d122b613f81ccfeafa6c2a4b16faed2f 62 SUPERFAMILY SSF141694 1 52 9.42E-11 T 23-10-2018 A3L01_00070 d122b613f81ccfeafa6c2a4b16faed2f 62 Gene3D G3DSA:4.10.1150.10 1 60 2.6E-7 T 23-10-2018 IPR024069 AF2212-like domain superfamily A3L01_00070 d122b613f81ccfeafa6c2a4b16faed2f 62 Pfam PF01954 Protein of unknown function DUF104 1 58 1.5E-11 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 A3L01_01370 ac4cdf467e0cb2792a6d4c1f0ccbfce6 293 Gene3D G3DSA:3.40.830.10 3 293 5.8E-69 T 23-10-2018 A3L01_01370 ac4cdf467e0cb2792a6d4c1f0ccbfce6 293 Hamap MF_00055 MEMO1 family protein . 3 292 60.148 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 A3L01_01370 ac4cdf467e0cb2792a6d4c1f0ccbfce6 293 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 5 290 2.1E-90 T 23-10-2018 A3L01_01370 ac4cdf467e0cb2792a6d4c1f0ccbfce6 293 SUPERFAMILY SSF53213 57 275 1.41E-7 T 23-10-2018 A3L01_01370 ac4cdf467e0cb2792a6d4c1f0ccbfce6 293 Pfam PF01875 Memo-like protein 7 290 1.2E-74 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 A3L01_01960 6145166089759828d00451d30d1068b8 1122 Pfam PF04561 RNA polymerase Rpb2, domain 2 175 348 4.8E-41 T 23-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01960 6145166089759828d00451d30d1068b8 1122 Gene3D G3DSA:2.40.50.150 683 874 5.0E-146 T 23-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01960 6145166089759828d00451d30d1068b8 1122 Pfam PF04566 RNA polymerase Rpb2, domain 4 521 584 4.8E-19 T 23-10-2018 IPR007646 RNA polymerase Rpb2, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01960 6145166089759828d00451d30d1068b8 1122 Pfam PF00562 RNA polymerase Rpb2, domain 6 653 1025 2.5E-132 T 23-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01960 6145166089759828d00451d30d1068b8 1122 Gene3D G3DSA:3.90.1100.10 21 177 1.4E-12 T 23-10-2018 A3L01_01960 6145166089759828d00451d30d1068b8 1122 ProSitePatterns PS01166 RNA polymerases beta chain signature. 878 890 - T 23-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01960 6145166089759828d00451d30d1068b8 1122 TIGRFAM TIGR03670 rpoB_arch: DNA-directed RNA polymerase subunit B 521 1121 0.0 T 23-10-2018 IPR019969 DNA-directed RNA polymerase subunit B (Rpo2) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01960 6145166089759828d00451d30d1068b8 1122 Gene3D G3DSA:3.90.1110.10 178 336 3.9E-59 T 23-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01960 6145166089759828d00451d30d1068b8 1122 Pfam PF04567 RNA polymerase Rpb2, domain 5 605 637 1.1E-8 T 23-10-2018 IPR007647 RNA polymerase Rpb2, domain 5 GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01960 6145166089759828d00451d30d1068b8 1122 Gene3D G3DSA:3.90.1100.10 337 511 3.6E-55 T 23-10-2018 A3L01_01960 6145166089759828d00451d30d1068b8 1122 Pfam PF04560 RNA polymerase Rpb2, domain 7 1027 1116 3.0E-31 T 23-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01960 6145166089759828d00451d30d1068b8 1122 Pfam PF04563 RNA polymerase beta subunit 28 381 1.5E-54 T 23-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01960 6145166089759828d00451d30d1068b8 1122 SUPERFAMILY SSF64484 12 1116 0.0 T 23-10-2018 A3L01_01960 6145166089759828d00451d30d1068b8 1122 Gene3D G3DSA:2.40.270.10 653 1011 5.0E-146 T 23-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01960 6145166089759828d00451d30d1068b8 1122 Gene3D G3DSA:3.90.1800.10 1012 1120 1.9E-41 T 23-10-2018 A3L01_01960 6145166089759828d00451d30d1068b8 1122 Pfam PF04565 RNA polymerase Rpb2, domain 3 424 488 3.4E-30 T 23-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_06265 2b724b7b332e6f7690a1061886b77dd8 112 Gene3D G3DSA:1.10.8.140 31 112 2.1E-27 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 A3L01_06265 2b724b7b332e6f7690a1061886b77dd8 112 Pfam PF01984 Double-stranded DNA-binding domain 8 111 1.5E-27 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 A3L01_06265 2b724b7b332e6f7690a1061886b77dd8 112 SUPERFAMILY SSF46950 8 111 2.49E-28 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 A3L01_06265 2b724b7b332e6f7690a1061886b77dd8 112 Hamap MF_00026 DNA-binding protein . 3 112 16.025 T 23-10-2018 IPR022889 DNA-binding protein, archaeal A3L01_06265 2b724b7b332e6f7690a1061886b77dd8 112 PIRSF PIRSF015730 1 112 1.3E-35 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 A3L01_07865 0e916c62dcb296bbfcab8e35341544bf 200 PRINTS PR00141 Proteasome component signature 146 157 1.1E-5 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L01_07865 0e916c62dcb296bbfcab8e35341544bf 200 PRINTS PR00141 Proteasome component signature 135 146 1.1E-5 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L01_07865 0e916c62dcb296bbfcab8e35341544bf 200 PRINTS PR00141 Proteasome component signature 15 30 1.1E-5 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L01_07865 0e916c62dcb296bbfcab8e35341544bf 200 Gene3D G3DSA:3.60.20.10 1 199 3.8E-62 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L01_07865 0e916c62dcb296bbfcab8e35341544bf 200 Hamap MF_02113_A Proteasome subunit beta [prcB]. 3 199 34.681 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A3L01_07865 0e916c62dcb296bbfcab8e35341544bf 200 SUPERFAMILY SSF56235 2 193 1.73E-59 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L01_07865 0e916c62dcb296bbfcab8e35341544bf 200 Pfam PF00227 Proteasome subunit 5 186 1.6E-52 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L01_07865 0e916c62dcb296bbfcab8e35341544bf 200 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 11 58 - T 23-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L01_07865 0e916c62dcb296bbfcab8e35341544bf 200 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 7 191 5.5E-78 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A3L01_06845 5037101fdfbf976c8f0d08577dd53d0d 225 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 1 220 3.0E-83 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L01_06845 5037101fdfbf976c8f0d08577dd53d0d 225 SUPERFAMILY SSF52402 1 220 5.35E-74 T 23-10-2018 A3L01_06845 5037101fdfbf976c8f0d08577dd53d0d 225 Gene3D G3DSA:3.90.1490.10 137 225 5.9E-31 T 23-10-2018 A3L01_06845 5037101fdfbf976c8f0d08577dd53d0d 225 Pfam PF01902 Diphthamide synthase 1 220 3.4E-85 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L01_06845 5037101fdfbf976c8f0d08577dd53d0d 225 TIGRFAM TIGR03679 arCOG00187: arCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein 4 217 6.7E-88 T 23-10-2018 IPR022427 Uncharacterised protein MJ0570, ATP-binding A3L01_06845 5037101fdfbf976c8f0d08577dd53d0d 225 PIRSF PIRSF039123 1 225 2.8E-80 T 23-10-2018 IPR030662 Diphthine--ammonia ligase/Uncharacterised protein MJ0570 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L01_06845 5037101fdfbf976c8f0d08577dd53d0d 225 TIGRFAM TIGR00289 TIGR00289: TIGR00289 family protein 1 221 9.2E-92 T 23-10-2018 IPR005237 Uncharacterised protein MJ0570 A3L01_06845 5037101fdfbf976c8f0d08577dd53d0d 225 Gene3D G3DSA:3.40.50.620 1 134 5.6E-48 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_07450 edecd5160e3f5db1e3fd318812e13fcd 388 Pfam PF01266 FAD dependent oxidoreductase 3 355 7.2E-74 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A3L01_07450 edecd5160e3f5db1e3fd318812e13fcd 388 Gene3D G3DSA:3.50.50.60 4 359 1.1E-116 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_07450 edecd5160e3f5db1e3fd318812e13fcd 388 SUPERFAMILY SSF51905 2 378 5.24E-61 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_07450 edecd5160e3f5db1e3fd318812e13fcd 388 Gene3D G3DSA:3.30.9.10 82 317 1.1E-116 T 23-10-2018 A3L01_07450 edecd5160e3f5db1e3fd318812e13fcd 388 SUPERFAMILY SSF54373 225 314 1.83E-7 T 23-10-2018 A3L01_02935 ac21c1707e8f5168926cb05c8cdbbd60 275 SUPERFAMILY SSF51430 14 269 1.03E-73 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A3L01_02935 ac21c1707e8f5168926cb05c8cdbbd60 275 Gene3D G3DSA:3.20.20.100 9 273 1.9E-86 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A3L01_02935 ac21c1707e8f5168926cb05c8cdbbd60 275 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 134 151 - T 23-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A3L01_02935 ac21c1707e8f5168926cb05c8cdbbd60 275 PRINTS PR00069 Aldo-keto reductase signature 134 151 5.5E-18 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L01_02935 ac21c1707e8f5168926cb05c8cdbbd60 275 PRINTS PR00069 Aldo-keto reductase signature 209 233 5.5E-18 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L01_02935 ac21c1707e8f5168926cb05c8cdbbd60 275 PRINTS PR00069 Aldo-keto reductase signature 46 70 5.5E-18 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L01_02935 ac21c1707e8f5168926cb05c8cdbbd60 275 PRINTS PR00069 Aldo-keto reductase signature 102 120 5.5E-18 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L01_02935 ac21c1707e8f5168926cb05c8cdbbd60 275 Pfam PF00248 Aldo/keto reductase family 18 270 6.9E-60 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain A3L01_04195 31cc20feb06266c92b8bfd4bf82095d2 191 Pfam PF12804 MobA-like NTP transferase domain 3 133 4.3E-19 T 23-10-2018 IPR025877 MobA-like NTP transferase A3L01_04195 31cc20feb06266c92b8bfd4bf82095d2 191 Gene3D G3DSA:3.90.550.10 2 175 3.3E-30 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_04195 31cc20feb06266c92b8bfd4bf82095d2 191 SUPERFAMILY SSF53448 2 167 1.35E-21 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_04035 8ec953a311e2bcff78f4c624487fc7d7 75 SMART SM00899 3 74 5.2E-21 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A3L01_04035 8ec953a311e2bcff78f4c624487fc7d7 75 Pfam PF04023 FeoA domain 3 73 1.5E-19 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A3L01_04035 8ec953a311e2bcff78f4c624487fc7d7 75 SUPERFAMILY SSF50037 5 74 8.7E-17 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal A3L01_04035 8ec953a311e2bcff78f4c624487fc7d7 75 Gene3D G3DSA:2.30.30.90 12 75 5.1E-22 T 23-10-2018 IPR038157 Ferrous iron transporter, core domain A3L01_00040 937587843ad94561d6c91d04fbc0aba3 466 Gene3D G3DSA:1.20.58.100 371 461 7.0E-17 T 23-10-2018 A3L01_00040 937587843ad94561d6c91d04fbc0aba3 466 Pfam PF02910 Fumarate reductase flavoprotein C-term 424 449 7.6E-6 T 23-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L01_00040 937587843ad94561d6c91d04fbc0aba3 466 SUPERFAMILY SSF46977 386 452 1.02E-18 T 23-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L01_00040 937587843ad94561d6c91d04fbc0aba3 466 Gene3D G3DSA:3.50.50.60 6 355 7.2E-111 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_00040 937587843ad94561d6c91d04fbc0aba3 466 SUPERFAMILY SSF51905 6 376 1.47E-46 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_00040 937587843ad94561d6c91d04fbc0aba3 466 Gene3D G3DSA:3.90.700.10 213 303 7.2E-111 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L01_00040 937587843ad94561d6c91d04fbc0aba3 466 SUPERFAMILY SSF56425 205 309 8.52E-34 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L01_00040 937587843ad94561d6c91d04fbc0aba3 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 5.4E-10 T 23-10-2018 A3L01_00040 937587843ad94561d6c91d04fbc0aba3 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 311 333 5.4E-10 T 23-10-2018 A3L01_00040 937587843ad94561d6c91d04fbc0aba3 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 164 182 5.4E-10 T 23-10-2018 A3L01_00040 937587843ad94561d6c91d04fbc0aba3 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.0E-5 T 23-10-2018 A3L01_00040 937587843ad94561d6c91d04fbc0aba3 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 167 176 1.0E-5 T 23-10-2018 A3L01_00040 937587843ad94561d6c91d04fbc0aba3 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 326 333 1.0E-5 T 23-10-2018 A3L01_00040 937587843ad94561d6c91d04fbc0aba3 466 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 4 448 3.3E-152 T 23-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L01_00040 937587843ad94561d6c91d04fbc0aba3 466 Pfam PF00890 FAD binding domain 6 348 5.1E-71 T 23-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L01_08720 8678ffea48c2ed00c086048aea642828 175 SUPERFAMILY SSF143243 6 160 2.88E-31 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_08720 8678ffea48c2ed00c086048aea642828 175 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 90 151 6.0E-16 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_08720 8678ffea48c2ed00c086048aea642828 175 Gene3D G3DSA:3.30.460.80 16 134 9.5E-17 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_08720 8678ffea48c2ed00c086048aea642828 175 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 36 151 2.5E-22 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_05605 e81f39d29bddb118dae164e9fbf35942 811 SUPERFAMILY SSF55729 489 644 9.11E-11 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L01_05605 e81f39d29bddb118dae164e9fbf35942 811 Gene3D G3DSA:3.40.50.12320 281 448 1.9E-33 T 23-10-2018 A3L01_05605 e81f39d29bddb118dae164e9fbf35942 811 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 39 807 48.198 T 23-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 A3L01_05605 e81f39d29bddb118dae164e9fbf35942 811 Pfam PF08351 Domain of unknown function (DUF1726) 129 221 1.5E-32 T 23-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 A3L01_05605 e81f39d29bddb118dae164e9fbf35942 811 Pfam PF05127 Helicase 285 458 2.0E-54 T 23-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 A3L01_05605 e81f39d29bddb118dae164e9fbf35942 811 SUPERFAMILY SSF52540 259 397 8.72E-7 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_05605 e81f39d29bddb118dae164e9fbf35942 811 Gene3D G3DSA:3.40.630.30 457 662 3.5E-55 T 23-10-2018 A3L01_05605 e81f39d29bddb118dae164e9fbf35942 811 Pfam PF13718 GNAT acetyltransferase 2 498 615 5.1E-34 T 23-10-2018 IPR000182 GNAT domain A3L01_05605 e81f39d29bddb118dae164e9fbf35942 811 Gene3D G3DSA:3.40.50.11040 24 252 1.8E-12 T 23-10-2018 A3L01_06700 adb11003dd362da973a7ea0455d977a3 337 Gene3D G3DSA:3.40.50.720 22 312 2.0E-71 T 23-10-2018 A3L01_06700 adb11003dd362da973a7ea0455d977a3 337 SUPERFAMILY SSF55347 134 288 2.29E-25 T 23-10-2018 A3L01_06700 adb11003dd362da973a7ea0455d977a3 337 Gene3D G3DSA:3.30.360.10 133 331 2.0E-71 T 23-10-2018 A3L01_06700 adb11003dd362da973a7ea0455d977a3 337 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 24 122 1.4E-20 T 23-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A3L01_06700 adb11003dd362da973a7ea0455d977a3 337 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 137 252 3.1E-9 T 23-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 A3L01_06700 adb11003dd362da973a7ea0455d977a3 337 SUPERFAMILY SSF51735 3 152 2.44E-37 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_03515 0c4b97290988adf69300cf5a04add5ab 207 Gene3D G3DSA:1.20.58.2140 3 202 6.3E-64 T 23-10-2018 A3L01_03515 0c4b97290988adf69300cf5a04add5ab 207 Pfam PF01997 Translin family 21 181 1.1E-10 T 23-10-2018 IPR002848 Translin family GO:0043565 Reactome: R-HSA-426486 A3L01_03515 0c4b97290988adf69300cf5a04add5ab 207 SUPERFAMILY SSF74784 1 182 1.44E-36 T 23-10-2018 IPR036081 Translin superfamily GO:0043565 Reactome: R-HSA-426486 A3L01_08420 5a507a130011bac942b190893c5b07ea 71 SUPERFAMILY SSF46785 13 57 5.39E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_05235 af2d4f6bf922b22300616a9f4fcd595b 295 SUPERFAMILY SSF54862 55 121 2.6E-16 T 23-10-2018 A3L01_05235 af2d4f6bf922b22300616a9f4fcd595b 295 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 71 82 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_05235 af2d4f6bf922b22300616a9f4fcd595b 295 SUPERFAMILY SSF52540 2 292 1.36E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_05235 af2d4f6bf922b22300616a9f4fcd595b 295 Pfam PF14697 4Fe-4S dicluster domain 64 117 3.7E-10 T 23-10-2018 A3L01_05235 af2d4f6bf922b22300616a9f4fcd595b 295 Gene3D G3DSA:3.30.70.20 69 115 2.0E-10 T 23-10-2018 A3L01_05235 af2d4f6bf922b22300616a9f4fcd595b 295 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 264 1.6E-23 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L01_05235 af2d4f6bf922b22300616a9f4fcd595b 295 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 100 111 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_00420 cc2a459de7af59fcc5362c2594877ba4 442 SUPERFAMILY SSF53335 143 439 5.88E-76 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_00420 cc2a459de7af59fcc5362c2594877ba4 442 Gene3D G3DSA:3.40.50.150 149 439 9.9E-87 T 23-10-2018 A3L01_00420 cc2a459de7af59fcc5362c2594877ba4 442 Pfam PF01189 16S rRNA methyltransferase RsmB/F 244 437 6.1E-62 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L01_00420 cc2a459de7af59fcc5362c2594877ba4 442 Gene3D G3DSA:1.10.940.10 2 148 4.4E-40 T 23-10-2018 IPR035926 NusB-like superfamily A3L01_00420 cc2a459de7af59fcc5362c2594877ba4 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 323 335 3.8E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_00420 cc2a459de7af59fcc5362c2594877ba4 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 255 265 3.8E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_00420 cc2a459de7af59fcc5362c2594877ba4 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 373 389 3.8E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_00420 cc2a459de7af59fcc5362c2594877ba4 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 422 439 3.8E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_00420 cc2a459de7af59fcc5362c2594877ba4 442 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 152 209 9.2E-9 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L01_06725 8e0449fe5353ee7589a8311b2c5f0ef4 273 SUPERFAMILY SSF161098 7 270 6.28E-61 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_06725 8e0449fe5353ee7589a8311b2c5f0ef4 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 267 5.6E-21 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_06725 8e0449fe5353ee7589a8311b2c5f0ef4 273 Gene3D G3DSA:1.10.3720.10 2 261 3.3E-53 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_09510 68d44217d776ea4b3fa73d09d51b527b 384 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 84 331 2.0E-33 T 23-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 A3L01_09510 68d44217d776ea4b3fa73d09d51b527b 384 TIGRFAM TIGR03812 tyr_de_CO2_Arch: tyrosine decarboxylase MnfA 8 379 4.5E-170 T 23-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A3L01_09510 68d44217d776ea4b3fa73d09d51b527b 384 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 224 245 - T 23-10-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 A3L01_09510 68d44217d776ea4b3fa73d09d51b527b 384 Gene3D G3DSA:3.40.640.10 40 290 1.0E-128 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L01_09510 68d44217d776ea4b3fa73d09d51b527b 384 Hamap MF_01610 Probable L-tyrosine/L-aspartate decarboxylase [mfnA]. 14 381 52.218 T 23-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A3L01_09510 68d44217d776ea4b3fa73d09d51b527b 384 Gene3D G3DSA:3.90.1150.10 6 374 1.0E-128 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L01_09510 68d44217d776ea4b3fa73d09d51b527b 384 SUPERFAMILY SSF53383 2 383 1.73E-106 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L01_01955 5cc650fb29cf330974c54fbf1b4cb11d 905 Gene3D G3DSA:3.30.1490.180 354 418 5.0E-81 T 23-10-2018 A3L01_01955 5cc650fb29cf330974c54fbf1b4cb11d 905 Gene3D G3DSA:1.20.120.1280 1 122 8.8E-31 T 23-10-2018 A3L01_01955 5cc650fb29cf330974c54fbf1b4cb11d 905 Gene3D G3DSA:1.20.120.1280 235 284 2.2E-11 T 23-10-2018 A3L01_01955 5cc650fb29cf330974c54fbf1b4cb11d 905 Pfam PF04998 RNA polymerase Rpb1, domain 5 811 876 3.7E-29 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01955 5cc650fb29cf330974c54fbf1b4cb11d 905 SUPERFAMILY SSF64484 4 887 0.0 T 23-10-2018 A3L01_01955 5cc650fb29cf330974c54fbf1b4cb11d 905 Pfam PF00623 RNA polymerase Rpb1, domain 2 321 487 2.4E-74 T 23-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01955 5cc650fb29cf330974c54fbf1b4cb11d 905 Gene3D G3DSA:1.10.274.100 491 671 7.1E-64 T 23-10-2018 A3L01_01955 5cc650fb29cf330974c54fbf1b4cb11d 905 Gene3D G3DSA:2.40.40.20 311 482 5.0E-81 T 23-10-2018 A3L01_01955 5cc650fb29cf330974c54fbf1b4cb11d 905 TIGRFAM TIGR02390 RNA_pol_rpoA1: DNA-directed RNA polymerase subunit A' 5 894 0.0 T 23-10-2018 IPR012758 DNA-directed RNA polymerase subunit A' (Rpo1N) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01955 5cc650fb29cf330974c54fbf1b4cb11d 905 SMART SM00663 211 515 3.0E-207 T 23-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01955 5cc650fb29cf330974c54fbf1b4cb11d 905 Gene3D G3DSA:1.10.132.30 672 813 3.0E-44 T 23-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01955 5cc650fb29cf330974c54fbf1b4cb11d 905 Gene3D G3DSA:2.20.25.410 850 900 6.4E-21 T 23-10-2018 A3L01_01955 5cc650fb29cf330974c54fbf1b4cb11d 905 Pfam PF04983 RNA polymerase Rpb1, domain 3 490 672 2.8E-37 T 23-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01955 5cc650fb29cf330974c54fbf1b4cb11d 905 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 319 2.8E-107 T 23-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01955 5cc650fb29cf330974c54fbf1b4cb11d 905 Pfam PF05000 RNA polymerase Rpb1, domain 4 699 804 7.2E-31 T 23-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_05945 e551cd71b032af434ae280711bba0fd6 204 Pfam PF01694 Rhomboid family 56 191 6.0E-30 T 23-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A3L01_05945 e551cd71b032af434ae280711bba0fd6 204 Gene3D G3DSA:1.20.1540.10 4 199 8.8E-37 T 23-10-2018 IPR035952 Rhomboid-like superfamily A3L01_05945 e551cd71b032af434ae280711bba0fd6 204 SUPERFAMILY SSF144091 9 194 4.32E-39 T 23-10-2018 A3L01_05270 cee917075c6925be14ef677fa6610b26 492 Gene3D G3DSA:1.20.1730.10 29 491 2.3E-92 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily A3L01_05270 cee917075c6925be14ef677fa6610b26 492 Pfam PF00474 Sodium:solute symporter family 41 440 8.1E-82 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A3L01_05270 cee917075c6925be14ef677fa6610b26 492 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 41 440 4.4E-78 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A3L01_03945 b7ef00b75d059687e3543be6af88899a 168 Pfam PF04167 Protein of unknown function (DUF402) 56 123 1.5E-14 T 23-10-2018 IPR007295 Domain of unknown function DUF402 A3L01_03945 b7ef00b75d059687e3543be6af88899a 168 Gene3D G3DSA:2.40.380.10 37 164 8.6E-13 T 23-10-2018 IPR035930 FomD-like superfamily A3L01_03945 b7ef00b75d059687e3543be6af88899a 168 SUPERFAMILY SSF159234 7 164 2.09E-37 T 23-10-2018 IPR035930 FomD-like superfamily A3L01_00230 00eb96fd5e2500066ac1737249f92add 98 Hamap MF_00545 30S ribosomal protein S24e [rps24e]. 1 98 21.646 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_00230 00eb96fd5e2500066ac1737249f92add 98 ProSitePatterns PS00529 Ribosomal protein S24e signature. 60 82 - T 23-10-2018 IPR018098 Ribosomal S24e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_00230 00eb96fd5e2500066ac1737249f92add 98 Pfam PF01282 Ribosomal protein S24e 21 97 7.0E-28 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_00230 00eb96fd5e2500066ac1737249f92add 98 Gene3D G3DSA:3.30.70.330 1 98 7.6E-39 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily A3L01_00230 00eb96fd5e2500066ac1737249f92add 98 SUPERFAMILY SSF54189 1 97 5.4E-33 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_00230 00eb96fd5e2500066ac1737249f92add 98 ProDom PD006052 RIBOSOMAL S24 40S RIBONUCLEOPROTEIN S24E 30S S24 CDNA RIKEN ACETYLATION 11 76 3.0E-27 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_00340 f44143a9f4e366aa4645b127f8ccf02b 264 Pfam PF00795 Carbon-nitrogen hydrolase 2 244 1.6E-59 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A3L01_00340 f44143a9f4e366aa4645b127f8ccf02b 264 SUPERFAMILY SSF56317 1 262 2.49E-75 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A3L01_00340 f44143a9f4e366aa4645b127f8ccf02b 264 Gene3D G3DSA:3.60.110.10 1 263 2.0E-104 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A3L01_05725 39bf47b3ddefa9a7354db16b7b6d4f3e 712 Pfam PF04471 Restriction endonuclease 20 124 9.5E-15 T 23-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 A3L01_05725 39bf47b3ddefa9a7354db16b7b6d4f3e 712 SUPERFAMILY SSF52980 20 129 4.08E-8 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L01_04530 94a32df57520781662a1c943749af8d7 361 Pfam PF01420 Type I restriction modification DNA specificity domain 2 119 2.2E-30 T 23-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A3L01_04530 94a32df57520781662a1c943749af8d7 361 Pfam PF01420 Type I restriction modification DNA specificity domain 154 337 3.1E-35 T 23-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A3L01_04530 94a32df57520781662a1c943749af8d7 361 SUPERFAMILY SSF116734 144 352 2.94E-53 T 23-10-2018 A3L01_04530 94a32df57520781662a1c943749af8d7 361 Gene3D G3DSA:1.10.287.1120 305 361 5.3E-12 T 23-10-2018 A3L01_04530 94a32df57520781662a1c943749af8d7 361 Gene3D G3DSA:3.90.220.20 140 304 4.5E-43 T 23-10-2018 A3L01_04530 94a32df57520781662a1c943749af8d7 361 SUPERFAMILY SSF116734 2 142 4.58E-36 T 23-10-2018 A3L01_04530 94a32df57520781662a1c943749af8d7 361 Gene3D G3DSA:3.90.220.20 1 119 1.9E-30 T 23-10-2018 A3L01_05595 8a69c65a92e2851a23ed504cd405efbe 173 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 31 104 4.0E-31 T 23-10-2018 A3L01_05595 8a69c65a92e2851a23ed504cd405efbe 173 SUPERFAMILY SSF53822 76 149 1.97E-5 T 23-10-2018 IPR028082 Periplasmic binding protein-like I A3L01_05595 8a69c65a92e2851a23ed504cd405efbe 173 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 18 163 1.9E-65 T 23-10-2018 IPR002790 Conserved hypothetical protein CHP00288 A3L01_05595 8a69c65a92e2851a23ed504cd405efbe 173 Pfam PF01936 NYN domain 32 163 2.6E-22 T 23-10-2018 IPR021139 NYN domain, limkain-b1-type A3L01_05595 8a69c65a92e2851a23ed504cd405efbe 173 Gene3D G3DSA:3.40.50.1010 22 165 1.1E-13 T 23-10-2018 A3L01_03695 2ad0144ad764270ce15dc839e15c201b 410 Gene3D G3DSA:3.40.50.2300 37 312 9.4E-90 T 23-10-2018 A3L01_03695 2ad0144ad764270ce15dc839e15c201b 410 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 38 335 1.5E-55 T 23-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 A3L01_03695 2ad0144ad764270ce15dc839e15c201b 410 Gene3D G3DSA:3.40.50.2300 138 323 9.4E-90 T 23-10-2018 A3L01_03695 2ad0144ad764270ce15dc839e15c201b 410 SUPERFAMILY SSF53822 50 292 6.06E-9 T 23-10-2018 IPR028082 Periplasmic binding protein-like I A3L01_03540 0cdf411554564f2bef60c02de4a7b861 214 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 204 4.0E-19 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L01_03540 0cdf411554564f2bef60c02de4a7b861 214 Gene3D G3DSA:3.60.21.10 1 213 2.7E-38 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L01_03540 0cdf411554564f2bef60c02de4a7b861 214 SUPERFAMILY SSF56300 2 206 4.24E-67 T 23-10-2018 A3L01_05085 84b10ae93a061ed66a87d70fce4c2bd6 205 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 1 177 5.1E-61 T 23-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A3L01_05085 84b10ae93a061ed66a87d70fce4c2bd6 205 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 137 158 - T 23-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 A3L01_05085 84b10ae93a061ed66a87d70fce4c2bd6 205 SUPERFAMILY SSF53850 1 201 1.05E-61 T 23-10-2018 A3L01_05085 84b10ae93a061ed66a87d70fce4c2bd6 205 Gene3D G3DSA:3.40.190.10 86 170 4.5E-65 T 23-10-2018 A3L01_05085 84b10ae93a061ed66a87d70fce4c2bd6 205 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 1 202 48.956 T 23-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 A3L01_05085 84b10ae93a061ed66a87d70fce4c2bd6 205 Gene3D G3DSA:3.40.190.10 3 193 4.5E-65 T 23-10-2018 A3L01_05085 84b10ae93a061ed66a87d70fce4c2bd6 205 Pfam PF01634 ATP phosphoribosyltransferase 46 197 1.7E-48 T 23-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A3L01_07770 a9320fac68602e3b3aafc5608e1c92c3 471 Hamap MF_01910 RNA-binding protein AU-1 [aubA]. 7 471 34.205 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 A3L01_07770 a9320fac68602e3b3aafc5608e1c92c3 471 SUPERFAMILY SSF159234 318 469 5.89E-31 T 23-10-2018 IPR035930 FomD-like superfamily A3L01_07770 a9320fac68602e3b3aafc5608e1c92c3 471 Pfam PF10150 Ribonuclease E/G family 152 263 6.6E-12 T 23-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 A3L01_07770 a9320fac68602e3b3aafc5608e1c92c3 471 Gene3D G3DSA:2.40.380.10 373 471 5.2E-10 T 23-10-2018 IPR035930 FomD-like superfamily A3L01_07770 a9320fac68602e3b3aafc5608e1c92c3 471 PIRSF PIRSF018644 5 471 9.7E-192 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 A3L01_07770 a9320fac68602e3b3aafc5608e1c92c3 471 Pfam PF04167 Protein of unknown function (DUF402) 379 443 8.3E-14 T 23-10-2018 IPR007295 Domain of unknown function DUF402 A3L01_06890 1652ccf05c18e3952b7e202f5818e087 172 Gene3D G3DSA:2.30.130.10 79 171 7.8E-35 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L01_06890 1652ccf05c18e3952b7e202f5818e087 172 TIGRFAM TIGR03684 arCOG00985: arCOG04150 universal archaeal PUA-domain protein 6 169 1.4E-56 T 23-10-2018 IPR022430 Conserved hypothetical protein CHP03684 A3L01_06890 1652ccf05c18e3952b7e202f5818e087 172 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 53 164 2.6E-28 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L01_06890 1652ccf05c18e3952b7e202f5818e087 172 PIRSF PIRSF005067 1 172 1.2E-42 T 23-10-2018 IPR016437 MCT-1/Tma20 A3L01_06890 1652ccf05c18e3952b7e202f5818e087 172 Pfam PF09183 Domain of unknown function (DUF1947) 6 75 3.0E-7 T 23-10-2018 IPR015266 Domain of unknown function DUF1947 A3L01_06890 1652ccf05c18e3952b7e202f5818e087 172 SMART SM00359 88 163 5.3E-23 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L01_06890 1652ccf05c18e3952b7e202f5818e087 172 SUPERFAMILY SSF88697 88 169 4.92E-23 T 23-10-2018 IPR015947 PUA-like superfamily A3L01_06890 1652ccf05c18e3952b7e202f5818e087 172 Pfam PF01472 PUA domain 89 161 2.2E-23 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L01_06890 1652ccf05c18e3952b7e202f5818e087 172 Gene3D G3DSA:3.10.450.120 1 78 6.7E-35 T 23-10-2018 A3L01_06640 21f1e4b7edd52c84d8bbc3e36a8c8f4a 142 Gene3D G3DSA:3.40.50.720 4 142 1.9E-47 T 23-10-2018 A3L01_06640 21f1e4b7edd52c84d8bbc3e36a8c8f4a 142 SMART SM00881 19 111 5.3E-27 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L01_06640 21f1e4b7edd52c84d8bbc3e36a8c8f4a 142 Pfam PF13380 CoA binding domain 23 137 2.5E-38 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L01_06640 21f1e4b7edd52c84d8bbc3e36a8c8f4a 142 SUPERFAMILY SSF51735 7 140 2.36E-43 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_08410 584615ce0301100a1c05c9c468c2f8b2 141 SMART SM00344 2 108 6.8E-48 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L01_08410 584615ce0301100a1c05c9c468c2f8b2 141 Pfam PF01037 Lrp/AsnC ligand binding domain 70 138 1.2E-13 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L01_08410 584615ce0301100a1c05c9c468c2f8b2 141 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 49 1.1E-14 T 23-10-2018 A3L01_08410 584615ce0301100a1c05c9c468c2f8b2 141 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 23-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A3L01_08410 584615ce0301100a1c05c9c468c2f8b2 141 Gene3D G3DSA:3.30.70.920 65 141 2.6E-19 T 23-10-2018 A3L01_08410 584615ce0301100a1c05c9c468c2f8b2 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 5.9E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_08410 584615ce0301100a1c05c9c468c2f8b2 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 5.9E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_08410 584615ce0301100a1c05c9c468c2f8b2 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 5.9E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_08410 584615ce0301100a1c05c9c468c2f8b2 141 SUPERFAMILY SSF46785 1 62 1.54E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_08410 584615ce0301100a1c05c9c468c2f8b2 141 Gene3D G3DSA:1.10.10.10 1 52 1.3E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_08410 584615ce0301100a1c05c9c468c2f8b2 141 SUPERFAMILY SSF54909 62 141 6.44E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L01_06745 df0066df67c8674e8e487e150d9682b7 339 Gene3D G3DSA:3.30.870.10 111 249 3.7E-47 T 23-10-2018 A3L01_06745 df0066df67c8674e8e487e150d9682b7 339 Gene3D G3DSA:1.10.10.10 1 104 1.4E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_06745 df0066df67c8674e8e487e150d9682b7 339 Gene3D G3DSA:2.30.30.690 250 339 7.1E-31 T 23-10-2018 A3L01_06745 df0066df67c8674e8e487e150d9682b7 339 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 11 78 9.4E-23 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L01_06745 df0066df67c8674e8e487e150d9682b7 339 SUPERFAMILY SSF159071 251 336 1.57E-20 T 23-10-2018 A3L01_06745 df0066df67c8674e8e487e150d9682b7 339 SUPERFAMILY SSF56024 111 246 1.19E-59 T 23-10-2018 A3L01_06745 df0066df67c8674e8e487e150d9682b7 339 SUPERFAMILY SSF46785 4 84 4.62E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_06745 df0066df67c8674e8e487e150d9682b7 339 Pfam PF11495 Archaeal transcriptional regulator TrmB 112 336 2.6E-36 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal A3L01_07810 8b553b4465809eff25acb5e1acafae27 395 Gene3D G3DSA:3.90.1150.10 35 385 3.2E-140 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L01_07810 8b553b4465809eff25acb5e1acafae27 395 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 7 394 8.9E-202 T 23-10-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type A3L01_07810 8b553b4465809eff25acb5e1acafae27 395 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 238 247 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A3L01_07810 8b553b4465809eff25acb5e1acafae27 395 SUPERFAMILY SSF53383 4 391 4.71E-120 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L01_07810 8b553b4465809eff25acb5e1acafae27 395 Gene3D G3DSA:3.40.640.10 55 291 3.2E-140 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L01_07810 8b553b4465809eff25acb5e1acafae27 395 Pfam PF00155 Aminotransferase class I and II 40 383 5.4E-71 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L01_02750 5d94b78f7d2a8dfd26a2c231f296d9b4 581 SMART SM00729 200 447 1.5E-32 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L01_02750 5d94b78f7d2a8dfd26a2c231f296d9b4 581 Pfam PF04055 Radical SAM superfamily 204 403 1.2E-24 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L01_02750 5d94b78f7d2a8dfd26a2c231f296d9b4 581 Gene3D G3DSA:3.80.30.20 200 457 2.1E-25 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L01_02750 5d94b78f7d2a8dfd26a2c231f296d9b4 581 SUPERFAMILY SSF102114 187 446 1.96E-26 T 23-10-2018 A3L01_02750 5d94b78f7d2a8dfd26a2c231f296d9b4 581 Gene3D G3DSA:1.10.150.320 518 568 4.1E-5 T 23-10-2018 A3L01_02750 5d94b78f7d2a8dfd26a2c231f296d9b4 581 SUPERFAMILY SSF47781 523 569 9.12E-6 T 23-10-2018 IPR010994 RuvA domain 2-like A3L01_01515 661940d2b7b9c5630ac831ee6253c150 663 Pfam PF09210 Domain of unknown function (DUF1957) 427 526 6.0E-27 T 23-10-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 A3L01_01515 661940d2b7b9c5630ac831ee6253c150 663 SUPERFAMILY SSF88713 2 416 2.97E-119 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L01_01515 661940d2b7b9c5630ac831ee6253c150 663 Pfam PF14520 Helix-hairpin-helix domain 610 656 3.6E-8 T 23-10-2018 A3L01_01515 661940d2b7b9c5630ac831ee6253c150 663 Gene3D G3DSA:3.20.110.10 1 416 2.4E-179 T 23-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily A3L01_01515 661940d2b7b9c5630ac831ee6253c150 663 Gene3D G3DSA:1.20.1430.10 417 563 1.3E-57 T 23-10-2018 IPR037090 Glycoside hydrolase families 57, central domain KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 A3L01_01515 661940d2b7b9c5630ac831ee6253c150 663 Gene3D G3DSA:1.10.150.20 609 663 4.7E-12 T 23-10-2018 A3L01_01515 661940d2b7b9c5630ac831ee6253c150 663 Pfam PF03065 Glycosyl hydrolase family 57 6 380 3.1E-69 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A3L01_01515 661940d2b7b9c5630ac831ee6253c150 663 SUPERFAMILY SSF88688 416 531 1.18E-31 T 23-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily A3L01_01515 661940d2b7b9c5630ac831ee6253c150 663 SUPERFAMILY SSF47794 610 661 2.51E-7 T 23-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 A3L01_10120 2fb77bd1f81b3b5cc7c9375dfef2ea8e 276 SUPERFAMILY SSF103481 39 133 1.83E-11 T 23-10-2018 A3L01_10120 2fb77bd1f81b3b5cc7c9375dfef2ea8e 276 SUPERFAMILY SSF103481 176 269 3.53E-14 T 23-10-2018 A3L01_10120 2fb77bd1f81b3b5cc7c9375dfef2ea8e 276 Pfam PF00892 EamA-like transporter family 139 269 3.1E-17 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L01_10120 2fb77bd1f81b3b5cc7c9375dfef2ea8e 276 Pfam PF00892 EamA-like transporter family 5 131 2.7E-19 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L01_00575 2a7ced5ba183a9db149d2a59e7a9412a 281 SMART SM00518 4 276 2.5E-88 T 23-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A3L01_00575 2a7ced5ba183a9db149d2a59e7a9412a 281 Gene3D G3DSA:3.20.20.150 12 281 1.8E-40 T 23-10-2018 A3L01_00575 2a7ced5ba183a9db149d2a59e7a9412a 281 Pfam PF01261 Xylose isomerase-like TIM barrel 30 239 2.0E-19 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A3L01_00575 2a7ced5ba183a9db149d2a59e7a9412a 281 SUPERFAMILY SSF51658 7 278 5.41E-61 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily A3L01_04915 77e21e7c5dd231075ef269492086f1ff 214 Pfam PF04967 HTH DNA binding domain 158 209 7.7E-19 T 23-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain A3L01_04915 77e21e7c5dd231075ef269492086f1ff 214 SUPERFAMILY SSF88659 155 210 1.09E-8 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A3L01_04915 77e21e7c5dd231075ef269492086f1ff 214 Gene3D G3DSA:1.10.10.10 133 213 2.6E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_07870 0f758afe999ef62d65144b81dc1349b9 363 Pfam PF13699 Domain of unknown function (DUF4157) 107 149 4.9E-5 T 23-10-2018 IPR025295 Domain of unknown function DUF4157 A3L01_01105 e6a59b7e4cf3be1e597c79b4b9525484 56 Pfam PF00253 Ribosomal protein S14p/S29e 8 55 4.4E-9 T 23-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01105 e6a59b7e4cf3be1e597c79b4b9525484 56 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 44 - T 23-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01105 e6a59b7e4cf3be1e597c79b4b9525484 56 Gene3D G3DSA:4.10.830.10 1 56 4.9E-20 T 23-10-2018 A3L01_01105 e6a59b7e4cf3be1e597c79b4b9525484 56 Hamap MF_01364_A 30S ribosomal protein S14 type Z [rpsZ]. 2 56 17.511 T 23-10-2018 IPR023676 Ribosomal protein S14, type Z, archaeal GO:0003723|GO:0003735|GO:0006412|GO:0015935 A3L01_00385 81274fee18efcd1f106b8473a6f9123e 112 SUPERFAMILY SSF117782 4 108 6.8E-36 T 23-10-2018 IPR035439 UPF0145 domain superfamily A3L01_00385 81274fee18efcd1f106b8473a6f9123e 112 Gene3D G3DSA:3.30.110.70 4 111 1.3E-32 T 23-10-2018 A3L01_00385 81274fee18efcd1f106b8473a6f9123e 112 Pfam PF01906 Putative heavy-metal-binding 5 106 1.4E-36 T 23-10-2018 IPR002765 Uncharacterised protein family UPF0145 A3L01_00385 81274fee18efcd1f106b8473a6f9123e 112 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 4 106 24.45 T 23-10-2018 IPR002765 Uncharacterised protein family UPF0145 A3L01_05225 e90d142a1d27d4b09ab95434ef1da1e5 147 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 8 138 2.9E-37 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 A3L01_05225 e90d142a1d27d4b09ab95434ef1da1e5 147 Gene3D G3DSA:1.10.287.370 1 147 1.1E-46 T 23-10-2018 IPR009053 Prefoldin A3L01_05225 e90d142a1d27d4b09ab95434ef1da1e5 147 Pfam PF02996 Prefoldin subunit 18 137 2.9E-27 T 23-10-2018 IPR004127 Prefoldin alpha-like A3L01_05225 e90d142a1d27d4b09ab95434ef1da1e5 147 SUPERFAMILY SSF46579 7 139 2.38E-30 T 23-10-2018 A3L01_05225 e90d142a1d27d4b09ab95434ef1da1e5 147 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 3 138 16.429 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 A3L01_09240 8ea801ab206631f8dcd1e41fe9ffa1a3 478 Pfam PF04415 Protein of unknown function (DUF515) 24 477 1.1E-139 T 23-10-2018 IPR007509 Protein of unknown function DUF515 A3L01_00050 50fca3d2d4d3538a8e5165e031c10e79 277 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 104 272 5.2E-51 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 A3L01_00050 50fca3d2d4d3538a8e5165e031c10e79 277 SUPERFAMILY SSF51690 104 273 1.73E-49 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A3L01_00050 50fca3d2d4d3538a8e5165e031c10e79 277 Gene3D G3DSA:3.20.20.70 120 263 1.7E-91 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_00050 50fca3d2d4d3538a8e5165e031c10e79 277 SUPERFAMILY SSF54675 5 103 1.37E-29 T 23-10-2018 A3L01_00050 50fca3d2d4d3538a8e5165e031c10e79 277 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 7 273 3.9E-98 T 23-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 A3L01_00050 50fca3d2d4d3538a8e5165e031c10e79 277 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 16 102 1.9E-30 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A3L01_00050 50fca3d2d4d3538a8e5165e031c10e79 277 Gene3D G3DSA:3.90.1170.20 9 271 1.7E-91 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 A3L01_00050 50fca3d2d4d3538a8e5165e031c10e79 277 PIRSF PIRSF006250 3 276 2.0E-92 T 23-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 A3L01_06580 bd6c962759eae902857ff99d7709970b 252 Gene3D G3DSA:1.10.3720.10 10 252 2.2E-66 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_06580 bd6c962759eae902857ff99d7709970b 252 SUPERFAMILY SSF161098 11 246 5.61E-49 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_06580 bd6c962759eae902857ff99d7709970b 252 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 247 7.6E-24 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_07410 19dd331280fbe7ca646c2f228ce18b94 424 Pfam PF03577 Peptidase family C69 50 218 1.0E-9 T 23-10-2018 IPR005322 Peptidase C69, dipeptidase A GO:0006508|GO:0016805 A3L01_07410 19dd331280fbe7ca646c2f228ce18b94 424 Gene3D G3DSA:3.60.60.10 2 300 3.0E-21 T 23-10-2018 A3L01_03080 5ef563cd126f8658cfc47f5551f050d4 154 Gene3D G3DSA:1.25.40.10 48 153 3.6E-19 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_03080 5ef563cd126f8658cfc47f5551f050d4 154 SUPERFAMILY SSF48452 52 134 4.03E-5 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_10330 494157bb17d5b17697475be485b9f260 341 Pfam PF13424 Tetratricopeptide repeat 57 120 2.0E-7 T 23-10-2018 A3L01_10330 494157bb17d5b17697475be485b9f260 341 Pfam PF13424 Tetratricopeptide repeat 133 203 6.1E-10 T 23-10-2018 A3L01_10330 494157bb17d5b17697475be485b9f260 341 Gene3D G3DSA:1.25.40.10 39 243 7.1E-27 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_10330 494157bb17d5b17697475be485b9f260 341 SMART SM00028 174 207 67.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L01_10330 494157bb17d5b17697475be485b9f260 341 SMART SM00028 134 167 18.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L01_10330 494157bb17d5b17697475be485b9f260 341 SMART SM00028 93 126 0.91 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L01_10330 494157bb17d5b17697475be485b9f260 341 SMART SM00028 55 88 17.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L01_10330 494157bb17d5b17697475be485b9f260 341 SUPERFAMILY SSF48452 44 238 4.74E-20 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_01680 c9d730486cc6d006cd8148f95889e255 370 Gene3D G3DSA:3.40.50.11740 62 303 1.0E-109 T 23-10-2018 A3L01_01680 c9d730486cc6d006cd8148f95889e255 370 PIRSF PIRSF005622 2 370 1.9E-142 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 A3L01_01680 c9d730486cc6d006cd8148f95889e255 370 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 6 367 6.3E-130 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 A3L01_01680 c9d730486cc6d006cd8148f95889e255 370 Gene3D G3DSA:1.10.10.2140 318 370 3.4E-25 T 23-10-2018 A3L01_01680 c9d730486cc6d006cd8148f95889e255 370 Pfam PF01924 Hydrogenase formation hypA family 13 367 3.7E-134 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 A3L01_01680 c9d730486cc6d006cd8148f95889e255 370 Gene3D G3DSA:3.40.50.11750 18 263 1.0E-109 T 23-10-2018 A3L01_00110 33c974d577950a65b0de5654b4f29ec7 380 Pfam PF06849 Protein of unknown function (DUF1246) 21 153 2.4E-42 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L01_00110 33c974d577950a65b0de5654b4f29ec7 380 PIRSF PIRSF004602 1 380 5.0E-143 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L01_00110 33c974d577950a65b0de5654b4f29ec7 380 Gene3D G3DSA:3.30.470.20 122 379 3.6E-93 T 23-10-2018 A3L01_00110 33c974d577950a65b0de5654b4f29ec7 380 Gene3D G3DSA:3.40.50.20 1 121 2.1E-42 T 23-10-2018 A3L01_00110 33c974d577950a65b0de5654b4f29ec7 380 Gene3D G3DSA:3.30.1490.20 152 218 3.6E-93 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L01_00110 33c974d577950a65b0de5654b4f29ec7 380 SUPERFAMILY SSF52440 1 133 1.06E-40 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L01_00110 33c974d577950a65b0de5654b4f29ec7 380 SUPERFAMILY SSF56059 139 380 1.16E-76 T 23-10-2018 A3L01_00110 33c974d577950a65b0de5654b4f29ec7 380 Pfam PF06973 Domain of unknown function (DUF1297) 189 380 3.0E-80 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 SUPERFAMILY SSF55608 765 879 4.65E-19 T 23-10-2018 IPR027434 Homing endonuclease A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 542 630 3.8E-9 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 Pfam PF14528 LAGLIDADG-like domain 783 864 2.3E-13 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 483 495 1.8E-6 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 400 413 1.8E-6 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 Gene3D G3DSA:2.170.16.10 546 672 3.6E-14 T 23-10-2018 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 Gene3D G3DSA:1.10.287.690 448 499 1.2E-23 T 23-10-2018 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 Gene3D G3DSA:2.170.16.10 856 924 7.4E-6 T 23-10-2018 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 Pfam PF14890 Intein splicing domain 553 929 4.6E-20 T 23-10-2018 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 SMART SM00306 539 655 4.4E-18 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 Gene3D G3DSA:3.30.342.10 3 366 6.2E-169 T 23-10-2018 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 Gene3D G3DSA:1.10.132.60 996 1162 6.3E-62 T 23-10-2018 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 Gene3D G3DSA:3.10.28.10 682 855 9.5E-25 T 23-10-2018 IPR027434 Homing endonuclease A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 929 1134 1.2E-71 T 23-10-2018 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 2 443 2.3E-88 T 23-10-2018 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 Pfam PF00136 DNA polymerase family B 930 1135 2.5E-30 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 Pfam PF00136 DNA polymerase family B 352 533 3.2E-44 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 908 930 4.8E-9 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 PRINTS PR00379 Intein signature 783 795 2.5E-22 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 PRINTS PR00379 Intein signature 906 923 2.5E-22 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 PRINTS PR00379 Intein signature 813 828 2.5E-22 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 PRINTS PR00379 Intein signature 924 933 2.5E-22 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 PRINTS PR00379 Intein signature 684 696 2.5E-22 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 SUPERFAMILY SSF53098 1 346 1.11E-86 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 SUPERFAMILY SSF51294 541 930 7.06E-25 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 Pfam PF03104 DNA polymerase family B, exonuclease domain 131 278 1.6E-34 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 Pfam PF03104 DNA polymerase family B, exonuclease domain 22 129 8.1E-13 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 SMART SM00486 133 548 1.5E-137 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 Gene3D G3DSA:3.90.1600.10 925 995 9.6E-17 T 23-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 SUPERFAMILY SSF56672 349 1148 3.56E-126 T 23-10-2018 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 Gene3D G3DSA:3.30.420.10 131 347 6.2E-169 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A3L01_00610 74ce48e48005388a145179f69ad7817d 1165 SMART SM00305 889 935 1.8E-12 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L01_09950 f0069e605024e12fbd3458841df9efac 443 SMART SM01230 100 343 1.4E-132 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L01_09950 f0069e605024e12fbd3458841df9efac 443 Gene3D G3DSA:3.30.590.10 103 443 3.5E-125 T 23-10-2018 A3L01_09950 f0069e605024e12fbd3458841df9efac 443 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 18 93 2.1E-20 T 23-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A3L01_09950 f0069e605024e12fbd3458841df9efac 443 SUPERFAMILY SSF55931 101 442 2.75E-121 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A3L01_09950 f0069e605024e12fbd3458841df9efac 443 Gene3D G3DSA:3.10.20.70 4 102 9.3E-24 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L01_09950 f0069e605024e12fbd3458841df9efac 443 SUPERFAMILY SSF54368 7 84 2.09E-20 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L01_09950 f0069e605024e12fbd3458841df9efac 443 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 10 441 9.5E-171 T 23-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L01_09950 f0069e605024e12fbd3458841df9efac 443 Pfam PF00120 Glutamine synthetase, catalytic domain 101 440 4.9E-126 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L01_09950 f0069e605024e12fbd3458841df9efac 443 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 226 241 - T 23-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A3L01_09950 f0069e605024e12fbd3458841df9efac 443 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 23-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A3L01_00045 ce1a911ec8835680e774f939f5d24a19 302 Hamap MF_00568 Quinolinate synthase A [nadA]. 4 301 44.999 T 23-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L01_00045 ce1a911ec8835680e774f939f5d24a19 302 SUPERFAMILY SSF142754 6 301 4.84E-114 T 23-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L01_00045 ce1a911ec8835680e774f939f5d24a19 302 Gene3D G3DSA:3.40.50.10800 8 282 2.8E-123 T 23-10-2018 A3L01_00045 ce1a911ec8835680e774f939f5d24a19 302 Gene3D G3DSA:3.40.50.10800 88 300 2.8E-123 T 23-10-2018 A3L01_00045 ce1a911ec8835680e774f939f5d24a19 302 Gene3D G3DSA:3.40.50.10800 173 257 2.8E-123 T 23-10-2018 A3L01_00045 ce1a911ec8835680e774f939f5d24a19 302 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 3 302 3.2E-114 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L01_00045 ce1a911ec8835680e774f939f5d24a19 302 Pfam PF02445 Quinolinate synthetase A protein 9 300 1.7E-111 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L01_00545 9dc6616fa3eac6ce492549331b086efe 145 SMART SM00529 25 125 4.4E-43 T 23-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 A3L01_00545 9dc6616fa3eac6ce492549331b086efe 145 Gene3D G3DSA:1.10.10.10 3 68 1.5E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_00545 9dc6616fa3eac6ce492549331b086efe 145 SUPERFAMILY SSF47979 64 137 2.09E-17 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 A3L01_00545 9dc6616fa3eac6ce492549331b086efe 145 SUPERFAMILY SSF46785 4 63 1.05E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_00545 9dc6616fa3eac6ce492549331b086efe 145 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 64 129 1.6E-20 T 23-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 A3L01_00545 9dc6616fa3eac6ce492549331b086efe 145 Gene3D G3DSA:1.10.60.10 69 124 7.1E-20 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 A3L01_00545 9dc6616fa3eac6ce492549331b086efe 145 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 4 58 2.6E-17 T 23-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 A3L01_06385 4c10385f54be5fddf40ef0147115f251 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 324 2.2E-46 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_06385 4c10385f54be5fddf40ef0147115f251 325 SUPERFAMILY SSF161098 81 307 3.4E-8 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_07885 922dd0df16a427a6bf01bd5d6a506b3d 425 SUPERFAMILY SSF52540 16 222 5.02E-15 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_07885 922dd0df16a427a6bf01bd5d6a506b3d 425 Pfam PF13635 Domain of unknown function (DUF4143) 214 349 9.2E-9 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 A3L01_07885 922dd0df16a427a6bf01bd5d6a506b3d 425 Pfam PF13173 AAA domain 32 155 2.4E-28 T 23-10-2018 A3L01_02015 4f6bdab17d6b493c3c4cabb12456f4ae 226 TIGRFAM TIGR00024 SbcD_rel_arch: putative phosphoesterase 7 220 7.7E-47 T 23-10-2018 IPR004376 Conserved hypothetical protein CHP00024, phosphoesterase-like A3L01_02015 4f6bdab17d6b493c3c4cabb12456f4ae 226 SUPERFAMILY SSF56300 15 126 1.48E-14 T 23-10-2018 A3L01_02015 4f6bdab17d6b493c3c4cabb12456f4ae 226 Gene3D G3DSA:3.60.21.10 9 151 3.7E-9 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L01_02015 4f6bdab17d6b493c3c4cabb12456f4ae 226 PIRSF PIRSF000887 3 224 3.6E-59 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 A3L01_02015 4f6bdab17d6b493c3c4cabb12456f4ae 226 Pfam PF00149 Calcineurin-like phosphoesterase 15 112 3.9E-7 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L01_05760 5b309f8dc43ae096d58257b4db0b05ca 154 SUPERFAMILY SSF46785 13 135 1.82E-22 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_05760 5b309f8dc43ae096d58257b4db0b05ca 154 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 2.0E-16 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L01_05760 5b309f8dc43ae096d58257b4db0b05ca 154 Gene3D G3DSA:1.10.10.10 1 102 4.9E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_03740 8dc948927cbc782b567ef72a4e3abbc9 353 SUPERFAMILY SSF54534 3 156 4.91E-42 T 23-10-2018 A3L01_03740 8dc948927cbc782b567ef72a4e3abbc9 353 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 4 154 2.2E-17 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A3L01_03740 8dc948927cbc782b567ef72a4e3abbc9 353 Gene3D G3DSA:3.10.50.80 3 164 5.6E-51 T 23-10-2018 A3L01_09810 f6a4e7bd23501a84fbeedc1f1ec2fbec 230 Pfam PF02080 TrkA-C domain 153 221 1.7E-10 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A3L01_09810 f6a4e7bd23501a84fbeedc1f1ec2fbec 230 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 4.9E-14 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L01_09810 f6a4e7bd23501a84fbeedc1f1ec2fbec 230 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 4.9E-14 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L01_09810 f6a4e7bd23501a84fbeedc1f1ec2fbec 230 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 4.9E-14 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L01_09810 f6a4e7bd23501a84fbeedc1f1ec2fbec 230 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 4.9E-14 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L01_09810 f6a4e7bd23501a84fbeedc1f1ec2fbec 230 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 4.9E-14 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L01_09810 f6a4e7bd23501a84fbeedc1f1ec2fbec 230 Gene3D G3DSA:3.40.50.720 1 140 9.3E-42 T 23-10-2018 A3L01_09810 f6a4e7bd23501a84fbeedc1f1ec2fbec 230 Gene3D G3DSA:3.30.70.1450 141 223 1.0E-13 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L01_09810 f6a4e7bd23501a84fbeedc1f1ec2fbec 230 SUPERFAMILY SSF116726 135 221 1.02E-10 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L01_09810 f6a4e7bd23501a84fbeedc1f1ec2fbec 230 Pfam PF02254 TrkA-N domain 3 124 1.6E-29 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A3L01_09810 f6a4e7bd23501a84fbeedc1f1ec2fbec 230 SUPERFAMILY SSF51735 1 144 2.72E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_08715 03a0d93f5c2f99e2a59b155641eb4473 167 SUPERFAMILY SSF56770 31 158 2.35E-51 T 23-10-2018 A3L01_08715 03a0d93f5c2f99e2a59b155641eb4473 167 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 43 152 8.3E-27 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_08715 03a0d93f5c2f99e2a59b155641eb4473 167 Gene3D G3DSA:3.40.50.12280 7 167 2.1E-50 T 23-10-2018 A3L01_02550 b17fe11e73dd7d3a58daaa62d4a66122 345 Gene3D G3DSA:3.40.630.10 7 332 9.2E-130 T 23-10-2018 A3L01_02550 b17fe11e73dd7d3a58daaa62d4a66122 345 Pfam PF05343 M42 glutamyl aminopeptidase 45 329 3.2E-95 T 23-10-2018 IPR008007 Peptidase M42 A3L01_02550 b17fe11e73dd7d3a58daaa62d4a66122 345 PIRSF PIRSF001123 1 344 3.1E-100 T 23-10-2018 IPR008007 Peptidase M42 A3L01_02550 b17fe11e73dd7d3a58daaa62d4a66122 345 SUPERFAMILY SSF101821 68 176 2.29E-26 T 23-10-2018 A3L01_02550 b17fe11e73dd7d3a58daaa62d4a66122 345 Gene3D G3DSA:2.40.30.40 68 160 9.2E-130 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A3L01_02550 b17fe11e73dd7d3a58daaa62d4a66122 345 SUPERFAMILY SSF53187 4 340 4.84E-63 T 23-10-2018 A3L01_02285 14ba2046e8af9133684160ee1c77a2de 225 Gene3D G3DSA:3.40.50.11700 3 141 7.0E-7 T 23-10-2018 A3L01_02285 14ba2046e8af9133684160ee1c77a2de 225 TIGRFAM TIGR01884 cas_HTH: CRISPR locus-related DNA-binding protein 3 200 3.0E-37 T 23-10-2018 IPR010163 CRISPR locus-related putative DNA-binding protein Csa3 A3L01_02285 14ba2046e8af9133684160ee1c77a2de 225 SUPERFAMILY SSF46785 162 218 4.86E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_02285 14ba2046e8af9133684160ee1c77a2de 225 Gene3D G3DSA:1.10.10.10 153 221 3.7E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_02285 14ba2046e8af9133684160ee1c77a2de 225 Pfam PF13936 Helix-turn-helix domain 155 185 1.0E-7 T 23-10-2018 IPR025246 Transposase IS30-like HTH domain A3L01_00100 48cfc3aa315bf394a71117257bb37758 143 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 3 143 25.474 T 23-10-2018 IPR033747 Class I PurE A3L01_00100 48cfc3aa315bf394a71117257bb37758 143 PIRSF PIRSF001338 1 143 7.3E-57 T 23-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 A3L01_00100 48cfc3aa315bf394a71117257bb37758 143 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 3 142 4.2E-54 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A3L01_00100 48cfc3aa315bf394a71117257bb37758 143 Pfam PF00731 AIR carboxylase 2 142 5.7E-55 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A3L01_00100 48cfc3aa315bf394a71117257bb37758 143 Gene3D G3DSA:3.40.50.7700 2 143 3.7E-59 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 A3L01_00100 48cfc3aa315bf394a71117257bb37758 143 SUPERFAMILY SSF52255 1 142 6.28E-52 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 A3L01_00100 48cfc3aa315bf394a71117257bb37758 143 SMART SM01001 1 143 4.1E-68 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A3L01_04180 cdf5e611a57c2bd856c9a5158ec81ee5 136 SUPERFAMILY SSF101307 6 134 3.4E-35 T 23-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 A3L01_04180 cdf5e611a57c2bd856c9a5158ec81ee5 136 Pfam PF04608 Phosphatidylglycerophosphatase A 10 133 5.4E-10 T 23-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A3L01_04180 cdf5e611a57c2bd856c9a5158ec81ee5 136 TIGRFAM TIGR03161 ribazole_CobZ: alpha-ribazole phosphatase CobZ 10 134 2.9E-54 T 23-10-2018 IPR017577 Alpha-ribazole phosphatase, CobZ A3L01_04180 cdf5e611a57c2bd856c9a5158ec81ee5 136 Gene3D G3DSA:1.10.3760.10 3 136 9.3E-12 T 23-10-2018 A3L01_09480 d61419053c7fd5d897e81c7d0ce8a639 321 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 227 315 4.4E-27 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L01_09480 d61419053c7fd5d897e81c7d0ce8a639 321 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 229 295 5.1E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L01_09480 d61419053c7fd5d897e81c7d0ce8a639 321 SMART SM00382 30 227 2.3E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_09480 d61419053c7fd5d897e81c7d0ce8a639 321 Gene3D G3DSA:3.40.50.300 1 319 7.2E-88 T 23-10-2018 A3L01_09480 d61419053c7fd5d897e81c7d0ce8a639 321 SUPERFAMILY SSF52540 2 260 1.9E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_09480 d61419053c7fd5d897e81c7d0ce8a639 321 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_09480 d61419053c7fd5d897e81c7d0ce8a639 321 Pfam PF00005 ABC transporter 22 177 1.0E-20 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_03235 680f3264ac2413f2b33d17b36d7fe6f9 428 SMART SM00984 322 413 3.0E-34 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L01_03235 680f3264ac2413f2b33d17b36d7fe6f9 428 Gene3D G3DSA:3.40.50.720 11 206 3.0E-72 T 23-10-2018 A3L01_03235 680f3264ac2413f2b33d17b36d7fe6f9 428 PIRSF PIRSF000124 10 421 7.6E-81 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L01_03235 680f3264ac2413f2b33d17b36d7fe6f9 428 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 11 190 3.9E-51 T 23-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L01_03235 680f3264ac2413f2b33d17b36d7fe6f9 428 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 209 295 1.1E-23 T 23-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L01_03235 680f3264ac2413f2b33d17b36d7fe6f9 428 SUPERFAMILY SSF52413 311 412 4.97E-25 T 23-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 A3L01_03235 680f3264ac2413f2b33d17b36d7fe6f9 428 PIRSF PIRSF500136 1 425 1.4E-144 T 23-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A3L01_03235 680f3264ac2413f2b33d17b36d7fe6f9 428 SUPERFAMILY SSF51735 12 201 7.57E-50 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_03235 680f3264ac2413f2b33d17b36d7fe6f9 428 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 322 412 9.8E-24 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L01_03235 680f3264ac2413f2b33d17b36d7fe6f9 428 Gene3D G3DSA:3.40.50.720 240 428 5.5E-66 T 23-10-2018 A3L01_03235 680f3264ac2413f2b33d17b36d7fe6f9 428 SUPERFAMILY SSF48179 209 299 2.38E-26 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A3L01_03235 680f3264ac2413f2b33d17b36d7fe6f9 428 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 11 408 2.5E-125 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L01_02580 3350eb662ef19a59b346718f24890c19 626 Gene3D G3DSA:3.40.50.800 504 607 1.3E-34 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A3L01_02580 3350eb662ef19a59b346718f24890c19 626 Pfam PF08915 Archaea-specific editing domain of threonyl-tRNA synthetase 1 139 2.0E-56 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 A3L01_02580 3350eb662ef19a59b346718f24890c19 626 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 35 602 29.356 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L01_02580 3350eb662ef19a59b346718f24890c19 626 SUPERFAMILY SSF52954 504 606 8.76E-33 T 23-10-2018 A3L01_02580 3350eb662ef19a59b346718f24890c19 626 Gene3D G3DSA:3.30.930.10 203 494 1.9E-62 T 23-10-2018 A3L01_02580 3350eb662ef19a59b346718f24890c19 626 ProDom PD016189 SYNTHETASE LIGASE THREONYL-TRNA AMINOACYL-TRNA NUCLEOTIDE-BINDING BIOSYNTHESIS ATP-BINDING ZINC METAL-BINDING THRRS 1 139 4.0E-57 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 A3L01_02580 3350eb662ef19a59b346718f24890c19 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 428 456 1.6E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L01_02580 3350eb662ef19a59b346718f24890c19 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 506 518 1.6E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L01_02580 3350eb662ef19a59b346718f24890c19 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 471 484 1.6E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L01_02580 3350eb662ef19a59b346718f24890c19 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 294 322 1.6E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L01_02580 3350eb662ef19a59b346718f24890c19 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 351 1.6E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L01_02580 3350eb662ef19a59b346718f24890c19 626 Gene3D G3DSA:3.50.80.10 1 139 6.7E-58 T 23-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily A3L01_02580 3350eb662ef19a59b346718f24890c19 626 Pfam PF03129 Anticodon binding domain 513 602 4.2E-26 T 23-10-2018 IPR004154 Anticodon-binding A3L01_02580 3350eb662ef19a59b346718f24890c19 626 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 288 492 1.0E-18 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_02580 3350eb662ef19a59b346718f24890c19 626 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 24 603 1.1E-176 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L01_02580 3350eb662ef19a59b346718f24890c19 626 SUPERFAMILY SSF55681 207 489 3.83E-57 T 23-10-2018 A3L01_01225 1b37db765030aa1b453eb59868f55032 121 ProSitePatterns PS01106 Ribosomal protein L18e signature. 36 53 - T 23-10-2018 IPR021132 Ribosomal protein L18e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01225 1b37db765030aa1b453eb59868f55032 121 Pfam PF17135 Ribosomal protein 60S L18 and 50S L18e 12 120 1.3E-17 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P A3L01_01225 1b37db765030aa1b453eb59868f55032 121 SUPERFAMILY SSF52080 6 120 5.23E-31 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily A3L01_01225 1b37db765030aa1b453eb59868f55032 121 Gene3D G3DSA:3.100.10.10 6 121 1.0E-40 T 23-10-2018 A3L01_01225 1b37db765030aa1b453eb59868f55032 121 Hamap MF_00329 50S ribosomal protein L18e [rpl18e]. 5 121 30.848 T 23-10-2018 IPR022947 Ribosomal protein L18e, archaea A3L01_06680 9b049f37091af1fa7bc40089ce3d7dc6 367 Gene3D G3DSA:2.40.50.100 239 287 1.2E-8 T 23-10-2018 A3L01_06680 9b049f37091af1fa7bc40089ce3d7dc6 367 SMART SM00382 28 211 2.0E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_06680 9b049f37091af1fa7bc40089ce3d7dc6 367 Gene3D G3DSA:2.40.50.140 288 351 2.6E-33 T 23-10-2018 A3L01_06680 9b049f37091af1fa7bc40089ce3d7dc6 367 SUPERFAMILY SSF52540 4 242 4.64E-89 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06680 9b049f37091af1fa7bc40089ce3d7dc6 367 SUPERFAMILY SSF50331 237 366 4.37E-26 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L01_06680 9b049f37091af1fa7bc40089ce3d7dc6 367 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_06680 9b049f37091af1fa7bc40089ce3d7dc6 367 Pfam PF08402 TOBE domain 281 358 1.6E-8 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A3L01_06680 9b049f37091af1fa7bc40089ce3d7dc6 367 Gene3D G3DSA:3.40.50.300 1 238 8.8E-79 T 23-10-2018 A3L01_06680 9b049f37091af1fa7bc40089ce3d7dc6 367 Pfam PF00005 ABC transporter 20 161 3.4E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_05565 79f667272f150edb833d782b13799ba5 430 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 14 429 6.6E-128 T 23-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 A3L01_05565 79f667272f150edb833d782b13799ba5 430 Pfam PF00152 tRNA synthetases class II (D, K and N) 111 424 2.0E-86 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_05565 79f667272f150edb833d782b13799ba5 430 Gene3D G3DSA:3.30.930.10 105 430 1.4E-116 T 23-10-2018 A3L01_05565 79f667272f150edb833d782b13799ba5 430 SUPERFAMILY SSF50249 4 99 6.43E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_05565 79f667272f150edb833d782b13799ba5 430 SUPERFAMILY SSF55681 111 425 1.3E-87 T 23-10-2018 A3L01_05565 79f667272f150edb833d782b13799ba5 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 181 193 1.7E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_05565 79f667272f150edb833d782b13799ba5 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 345 361 1.7E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_05565 79f667272f150edb833d782b13799ba5 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 385 399 1.7E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_05565 79f667272f150edb833d782b13799ba5 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 197 210 1.7E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_05565 79f667272f150edb833d782b13799ba5 430 Pfam PF01336 OB-fold nucleic acid binding domain 19 97 2.2E-14 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L01_05565 79f667272f150edb833d782b13799ba5 430 Gene3D G3DSA:2.40.50.140 1 101 3.3E-29 T 23-10-2018 A3L01_05095 ca7f311a8ab9e0ec53f11057e6c30e62 178 Gene3D G3DSA:3.30.230.40 1 75 5.1E-22 T 23-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 A3L01_05095 ca7f311a8ab9e0ec53f11057e6c30e62 178 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 22 159 4.5E-39 T 23-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A3L01_05095 ca7f311a8ab9e0ec53f11057e6c30e62 178 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 141 153 - T 23-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A3L01_05095 ca7f311a8ab9e0ec53f11057e6c30e62 178 Gene3D G3DSA:3.30.230.40 76 176 3.9E-33 T 23-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 A3L01_05095 ca7f311a8ab9e0ec53f11057e6c30e62 178 SUPERFAMILY SSF54211 2 73 2.78E-16 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L01_05095 ca7f311a8ab9e0ec53f11057e6c30e62 178 SUPERFAMILY SSF54211 75 164 9.48E-26 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L01_03100 cc577cdb3f36f53fb81a1f7b80d2c6d5 270 SUPERFAMILY SSF100950 12 120 1.57E-6 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L01_09830 dc7a2aeb19dd0c7c202c33353e5c35ff 203 SUPERFAMILY SSF81573 13 67 3.34E-5 T 23-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily A3L01_09830 dc7a2aeb19dd0c7c202c33353e5c35ff 203 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 2 203 15.149 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L01_09830 dc7a2aeb19dd0c7c202c33353e5c35ff 203 Gene3D G3DSA:1.20.5.620 18 98 1.5E-25 T 23-10-2018 A3L01_09830 dc7a2aeb19dd0c7c202c33353e5c35ff 203 Gene3D G3DSA:3.30.2320.30 100 203 1.5E-18 T 23-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L01_09830 dc7a2aeb19dd0c7c202c33353e5c35ff 203 Pfam PF01991 ATP synthase (E/31 kDa) subunit 10 202 2.4E-39 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L01_09830 dc7a2aeb19dd0c7c202c33353e5c35ff 203 SUPERFAMILY SSF160527 82 203 7.32E-25 T 23-10-2018 A3L01_03980 1b3c5c8869b97b285e7a007ace7a1c6f 73 ProDom PD052018 AF1456 COIL COILED 14 72 0.009 T 23-10-2018 A3L01_09905 0b559fa9e5ee12dfbd8885b4f7bd2058 410 SUPERFAMILY SSF51338 17 62 3.02E-7 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L01_09905 0b559fa9e5ee12dfbd8885b4f7bd2058 410 Pfam PF01979 Amidohydrolase family 49 207 2.5E-11 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A3L01_09905 0b559fa9e5ee12dfbd8885b4f7bd2058 410 Pfam PF01979 Amidohydrolase family 262 388 8.0E-10 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A3L01_09905 0b559fa9e5ee12dfbd8885b4f7bd2058 410 SUPERFAMILY SSF51338 336 399 1.11E-22 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L01_09905 0b559fa9e5ee12dfbd8885b4f7bd2058 410 SUPERFAMILY SSF51556 53 335 2.99E-73 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L01_09905 0b559fa9e5ee12dfbd8885b4f7bd2058 410 ProSitePatterns PS00482 Dihydroorotase signature 1. 56 64 - T 23-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L01_09905 0b559fa9e5ee12dfbd8885b4f7bd2058 410 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 14 391 2.0E-118 T 23-10-2018 A3L01_09905 0b559fa9e5ee12dfbd8885b4f7bd2058 410 ProSitePatterns PS00483 Dihydroorotase signature 2. 275 286 - T 23-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L01_09905 0b559fa9e5ee12dfbd8885b4f7bd2058 410 Hamap MF_00220_A Dihydroorotase [pyrC]. 4 396 63.841 T 23-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L01_09905 0b559fa9e5ee12dfbd8885b4f7bd2058 410 Gene3D G3DSA:3.20.20.140 44 407 2.8E-106 T 23-10-2018 A3L01_00970 ad0cc079b880a8bb75ee257d1139d6c5 300 SUPERFAMILY SSF55681 6 295 3.04E-55 T 23-10-2018 A3L01_00970 ad0cc079b880a8bb75ee257d1139d6c5 300 Gene3D G3DSA:3.30.930.10 1 299 1.4E-72 T 23-10-2018 A3L01_00970 ad0cc079b880a8bb75ee257d1139d6c5 300 Pfam PF00152 tRNA synthetases class II (D, K and N) 3 292 2.6E-41 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_08380 633b1086406f6aebcd271ade0556a4f6 568 Pfam PF01472 PUA domain 512 566 5.8E-11 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L01_08380 633b1086406f6aebcd271ade0556a4f6 568 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 439 498 2.2E-6 T 23-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L01_08380 633b1086406f6aebcd271ade0556a4f6 568 Gene3D G3DSA:3.40.50.10630 252 423 1.8E-46 T 23-10-2018 A3L01_08380 633b1086406f6aebcd271ade0556a4f6 568 SUPERFAMILY SSF52141 265 421 1.96E-40 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L01_08380 633b1086406f6aebcd271ade0556a4f6 568 Gene3D G3DSA:2.30.130.10 502 568 1.5E-24 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L01_08380 633b1086406f6aebcd271ade0556a4f6 568 SUPERFAMILY SSF88802 248 498 6.54E-17 T 23-10-2018 A3L01_08380 633b1086406f6aebcd271ade0556a4f6 568 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 511 565 2.3E-8 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L01_08380 633b1086406f6aebcd271ade0556a4f6 568 SMART SM00359 502 568 1.6E-7 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L01_08380 633b1086406f6aebcd271ade0556a4f6 568 SUPERFAMILY SSF51713 1 243 2.88E-18 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L01_08380 633b1086406f6aebcd271ade0556a4f6 568 SUPERFAMILY SSF88697 511 566 3.98E-13 T 23-10-2018 IPR015947 PUA-like superfamily A3L01_09465 480fe1dc7a6a13df8e38607d956c341e 605 Gene3D G3DSA:3.90.76.10 41 188 1.9E-150 T 23-10-2018 A3L01_09465 480fe1dc7a6a13df8e38607d956c341e 605 SUPERFAMILY SSF53850 28 542 6.36E-104 T 23-10-2018 A3L01_09465 480fe1dc7a6a13df8e38607d956c341e 605 PIRSF PIRSF002741 1 538 1.7E-71 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A3L01_09465 480fe1dc7a6a13df8e38607d956c341e 605 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 73 456 3.3E-73 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain A3L01_09465 480fe1dc7a6a13df8e38607d956c341e 605 Gene3D G3DSA:3.10.105.10 278 516 1.9E-150 T 23-10-2018 A3L01_09465 480fe1dc7a6a13df8e38607d956c341e 605 Gene3D G3DSA:3.40.190.10 39 544 1.9E-150 T 23-10-2018 A3L01_09465 480fe1dc7a6a13df8e38607d956c341e 605 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 585 604 1.1E-6 T 23-10-2018 IPR027552 CGP-CTERM domain A3L01_01510 501fcad87e4e627b98c5bab700c5e3d9 649 Gene3D G3DSA:2.30.310.10 5 150 3.0E-32 T 23-10-2018 A3L01_01510 501fcad87e4e627b98c5bab700c5e3d9 649 SUPERFAMILY SSF46946 172 221 1.18E-5 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A3L01_01510 501fcad87e4e627b98c5bab700c5e3d9 649 Pfam PF05670 Domain of unknown function (DUF814) 454 552 7.4E-26 T 23-10-2018 IPR008532 Domain of unknown function DUF814 A3L01_01510 501fcad87e4e627b98c5bab700c5e3d9 649 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 7 435 4.2E-83 T 23-10-2018 A3L01_02675 d2ceb06bd395f1109c2fb7373752ac90 501 SUPERFAMILY SSF46785 2 70 1.58E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_02675 d2ceb06bd395f1109c2fb7373752ac90 501 SUPERFAMILY SSF46785 71 142 1.03E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_02675 d2ceb06bd395f1109c2fb7373752ac90 501 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 168 498 2.6E-94 T 23-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A3L01_02675 d2ceb06bd395f1109c2fb7373752ac90 501 Pfam PF01409 tRNA synthetases class II core domain (F) 224 496 1.3E-81 T 23-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 A3L01_02675 d2ceb06bd395f1109c2fb7373752ac90 501 Gene3D G3DSA:3.30.930.10 194 501 5.6E-89 T 23-10-2018 A3L01_02675 d2ceb06bd395f1109c2fb7373752ac90 501 SUPERFAMILY SSF55681 225 498 8.58E-59 T 23-10-2018 A3L01_02675 d2ceb06bd395f1109c2fb7373752ac90 501 Hamap MF_00282 Phenylalanine--tRNA ligase alpha subunit [pheS]. 2 498 37.801 T 23-10-2018 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 A3L01_02675 d2ceb06bd395f1109c2fb7373752ac90 501 Gene3D G3DSA:1.10.10.10 1 111 1.9E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_04300 a9b4d30f797da28153704f19f81b60f4 301 Pfam PF01435 Peptidase family M48 70 291 3.0E-38 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A3L01_04300 a9b4d30f797da28153704f19f81b60f4 301 Gene3D G3DSA:3.30.2010.10 61 152 9.5E-32 T 23-10-2018 A3L01_04300 a9b4d30f797da28153704f19f81b60f4 301 Hamap MF_00188 Protease HtpX [htpX]. 2 291 27.822 T 23-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 A3L01_09420 c1e9ebcfe6a1c593448fe7793ea8638b 181 Pfam PF01583 Adenylylsulphate kinase 9 160 1.9E-60 T 23-10-2018 A3L01_09420 c1e9ebcfe6a1c593448fe7793ea8638b 181 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 5 172 1.1E-68 T 23-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A3L01_09420 c1e9ebcfe6a1c593448fe7793ea8638b 181 Gene3D G3DSA:3.40.50.300 6 181 1.7E-60 T 23-10-2018 A3L01_09420 c1e9ebcfe6a1c593448fe7793ea8638b 181 SUPERFAMILY SSF52540 6 177 6.81E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_09420 c1e9ebcfe6a1c593448fe7793ea8638b 181 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 8 178 37.159 T 23-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A3L01_05340 2d03eb2c0c53ba5a50497a790f9bf65b 177 SUPERFAMILY SSF54631 5 125 9.1E-31 T 23-10-2018 A3L01_05340 2d03eb2c0c53ba5a50497a790f9bf65b 177 Gene3D G3DSA:3.10.580.10 3 175 1.8E-41 T 23-10-2018 A3L01_05340 2d03eb2c0c53ba5a50497a790f9bf65b 177 SMART SM00116 14 61 6.5E-9 T 23-10-2018 IPR000644 CBS domain A3L01_05340 2d03eb2c0c53ba5a50497a790f9bf65b 177 SMART SM00116 79 126 9.3E-9 T 23-10-2018 IPR000644 CBS domain A3L01_05340 2d03eb2c0c53ba5a50497a790f9bf65b 177 Pfam PF00571 CBS domain 72 125 1.2E-10 T 23-10-2018 IPR000644 CBS domain A3L01_05340 2d03eb2c0c53ba5a50497a790f9bf65b 177 Pfam PF00571 CBS domain 7 60 1.6E-11 T 23-10-2018 IPR000644 CBS domain A3L01_08305 052d189b18ba5b6faf5ecbbbab709a6b 398 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 3 387 3.6E-96 T 23-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A3L01_08305 052d189b18ba5b6faf5ecbbbab709a6b 398 Gene3D G3DSA:2.40.30.110 309 383 1.2E-30 T 23-10-2018 A3L01_08305 052d189b18ba5b6faf5ecbbbab709a6b 398 SUPERFAMILY SSF101790 300 392 5.72E-25 T 23-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal A3L01_08305 052d189b18ba5b6faf5ecbbbab709a6b 398 PIRSF PIRSF006487 1 398 5.9E-106 T 23-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A3L01_08305 052d189b18ba5b6faf5ecbbbab709a6b 398 Pfam PF01571 Aminomethyltransferase folate-binding domain 8 287 1.3E-96 T 23-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain A3L01_08305 052d189b18ba5b6faf5ecbbbab709a6b 398 Gene3D G3DSA:4.10.1250.10 268 305 2.7E-9 T 23-10-2018 A3L01_08305 052d189b18ba5b6faf5ecbbbab709a6b 398 Gene3D G3DSA:3.30.70.1400 52 143 1.5E-90 T 23-10-2018 A3L01_08305 052d189b18ba5b6faf5ecbbbab709a6b 398 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 389 43.461 T 23-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A3L01_08305 052d189b18ba5b6faf5ecbbbab709a6b 398 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 293 383 4.7E-25 T 23-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A3L01_08305 052d189b18ba5b6faf5ecbbbab709a6b 398 SUPERFAMILY SSF103025 2 307 1.04E-93 T 23-10-2018 A3L01_08305 052d189b18ba5b6faf5ecbbbab709a6b 398 Gene3D G3DSA:3.30.1360.120 8 255 1.5E-90 T 23-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 A3L01_09580 b476f6f67eb2dc23dc8ee6ad3574e3d5 374 Gene3D G3DSA:1.20.1530.20 1 374 3.3E-85 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L01_09580 b476f6f67eb2dc23dc8ee6ad3574e3d5 374 Pfam PF00999 Sodium/hydrogen exchanger family 9 371 1.0E-68 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L01_07130 d80d71513104afa404dc1da508d8745e 157 PIRSF PIRSF005216 2 157 1.2E-46 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L01_07130 d80d71513104afa404dc1da508d8745e 157 Hamap MF_01404 Pyruvoyl-dependent arginine decarboxylase [pdaD]. 1 157 46.436 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L01_07130 d80d71513104afa404dc1da508d8745e 157 Pfam PF01862 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) 5 154 1.7E-40 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L01_07130 d80d71513104afa404dc1da508d8745e 157 SUPERFAMILY SSF56271 2 155 4.97E-45 T 23-10-2018 IPR016104 Pyruvoyl-dependent histidine/arginine decarboxylase GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L01_07130 d80d71513104afa404dc1da508d8745e 157 ProDom PD010449 DECARBOXYLASE PYRUVOYL-DEPENDENT ARGININE SUBUNIT ALPHA CONTAINS: BETA PVLARGDC LYA DECARBOX 6 141 6.0E-69 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L01_07130 d80d71513104afa404dc1da508d8745e 157 Gene3D G3DSA:3.30.60.30 1 43 1.7E-18 T 23-10-2018 A3L01_07130 d80d71513104afa404dc1da508d8745e 157 Gene3D G3DSA:3.50.20.10 44 156 2.2E-33 T 23-10-2018 IPR016105 Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L01_07130 d80d71513104afa404dc1da508d8745e 157 TIGRFAM TIGR00286 TIGR00286: arginine decarboxylase, pyruvoyl-dependent 6 154 7.8E-39 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L01_03300 d4181293a17cfef4e45321cf96ff0ce7 130 Gene3D G3DSA:3.50.30.10 1 130 1.1E-49 T 23-10-2018 A3L01_03300 d4181293a17cfef4e45321cf96ff0ce7 130 SUPERFAMILY SSF52016 1 128 6.04E-44 T 23-10-2018 A3L01_03300 d4181293a17cfef4e45321cf96ff0ce7 130 Pfam PF01989 Protein of unknown function DUF126 24 103 1.2E-35 T 23-10-2018 IPR002840 Aconitase X swivel domain, putative A3L01_03300 d4181293a17cfef4e45321cf96ff0ce7 130 Hamap MF_00078 UPF0107 protein . 2 129 33.792 T 23-10-2018 IPR020794 Aconitase X subunit 2, archaeal, putative A3L01_03300 d4181293a17cfef4e45321cf96ff0ce7 130 PIRSF PIRSF004966 1 130 1.3E-53 T 23-10-2018 IPR012016 Aconitase X subunit 2, putative A3L01_01700 9c50bcb15c268967766538914ed2e3de 159 PRINTS PR00446 Hydrogen uptake protein signature 67 77 4.8E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L01_01700 9c50bcb15c268967766538914ed2e3de 159 PRINTS PR00446 Hydrogen uptake protein signature 13 25 4.8E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L01_01700 9c50bcb15c268967766538914ed2e3de 159 PRINTS PR00446 Hydrogen uptake protein signature 25 36 4.8E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L01_01700 9c50bcb15c268967766538914ed2e3de 159 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 14 150 1.2E-31 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L01_01700 9c50bcb15c268967766538914ed2e3de 159 Pfam PF01750 Hydrogenase maturation protease 30 131 7.3E-14 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L01_01700 9c50bcb15c268967766538914ed2e3de 159 SUPERFAMILY SSF53163 12 156 5.23E-31 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L01_01700 9c50bcb15c268967766538914ed2e3de 159 Gene3D G3DSA:3.40.50.1450 9 158 4.2E-41 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L01_04055 cbbd5b734eb44990816e899ea0c84380 267 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 133 255 1.4E-21 T 23-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal A3L01_04055 cbbd5b734eb44990816e899ea0c84380 267 PIRSF PIRSF019073 3 267 3.1E-76 T 23-10-2018 IPR014499 Diadenylate cyclase, DacZ-type A3L01_04055 cbbd5b734eb44990816e899ea0c84380 267 Hamap MF_00840 Diadenylate cyclase [dacZ]. 8 266 34.237 T 23-10-2018 IPR014499 Diadenylate cyclase, DacZ-type A3L01_04055 cbbd5b734eb44990816e899ea0c84380 267 Gene3D G3DSA:3.40.1700.10 177 265 7.6E-15 T 23-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily A3L01_04055 cbbd5b734eb44990816e899ea0c84380 267 SUPERFAMILY SSF143597 94 260 1.57E-30 T 23-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily A3L01_00010 7fafff357c916ba160092531529e72b3 293 Pfam PF00005 ABC transporter 19 158 7.0E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_00010 7fafff357c916ba160092531529e72b3 293 SUPERFAMILY SSF52540 3 219 7.1E-62 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_00010 7fafff357c916ba160092531529e72b3 293 Gene3D G3DSA:3.40.50.300 2 264 1.0E-65 T 23-10-2018 A3L01_00010 7fafff357c916ba160092531529e72b3 293 SMART SM00382 28 214 1.4E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_03815 05645105ad778c0041208d8893c636c1 257 Pfam PF00753 Metallo-beta-lactamase superfamily 34 224 1.9E-16 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_03815 05645105ad778c0041208d8893c636c1 257 SUPERFAMILY SSF56281 17 241 1.19E-32 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_03815 05645105ad778c0041208d8893c636c1 257 SMART SM00849 33 224 1.6E-17 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_03815 05645105ad778c0041208d8893c636c1 257 Gene3D G3DSA:3.60.15.10 3 242 9.0E-43 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_01995 788bd40c880c4fa94bd415f3846cff8e 501 Pfam PF02347 Glycine cleavage system P-protein 30 309 4.6E-11 T 23-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A3L01_01995 788bd40c880c4fa94bd415f3846cff8e 501 Gene3D G3DSA:3.40.640.10 86 321 2.7E-61 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L01_01995 788bd40c880c4fa94bd415f3846cff8e 501 Gene3D G3DSA:3.90.1150.10 339 474 1.7E-44 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L01_01995 788bd40c880c4fa94bd415f3846cff8e 501 SUPERFAMILY SSF53383 12 487 3.9E-124 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L01_01995 788bd40c880c4fa94bd415f3846cff8e 501 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 10 489 61.554 T 23-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 A3L01_00055 ad45cd756a1689fbc022483c8875bbb2 335 Gene3D G3DSA:3.20.20.70 1 316 3.5E-151 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_00055 ad45cd756a1689fbc022483c8875bbb2 335 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 15 334 3.5E-145 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L01_00055 ad45cd756a1689fbc022483c8875bbb2 335 PIRSF PIRSF029271 2 335 5.0E-147 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L01_00055 ad45cd756a1689fbc022483c8875bbb2 335 Pfam PF05690 Thiazole biosynthesis protein ThiG 245 299 8.7E-8 T 23-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A3L01_00055 ad45cd756a1689fbc022483c8875bbb2 335 SUPERFAMILY SSF51366 24 312 4.52E-59 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L01_00055 ad45cd756a1689fbc022483c8875bbb2 335 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 10 335 53.177 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L01_00055 ad45cd756a1689fbc022483c8875bbb2 335 Pfam PF01680 SOR/SNZ family 13 213 3.5E-95 T 23-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L01_08000 f6112df0ce0a005dc03568e5e07e256f 1075 Gene3D G3DSA:3.10.620.30 180 325 6.1E-21 T 23-10-2018 A3L01_08000 f6112df0ce0a005dc03568e5e07e256f 1075 Pfam PF13620 Carboxypeptidase regulatory-like domain 632 703 1.5E-7 T 23-10-2018 A3L01_08000 f6112df0ce0a005dc03568e5e07e256f 1075 SUPERFAMILY SSF49464 632 703 1.18E-5 T 23-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily A3L01_08000 f6112df0ce0a005dc03568e5e07e256f 1075 Pfam PF01841 Transglutaminase-like superfamily 202 314 9.7E-23 T 23-10-2018 IPR002931 Transglutaminase-like A3L01_08000 f6112df0ce0a005dc03568e5e07e256f 1075 SMART SM00460 248 316 2.0E-17 T 23-10-2018 IPR002931 Transglutaminase-like A3L01_08000 f6112df0ce0a005dc03568e5e07e256f 1075 SUPERFAMILY SSF54001 197 322 6.87E-27 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A3L01_03350 a6324a5507dbb169a8f46b057d4a42f9 351 SMART SM00981 60 149 8.6E-26 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L01_03350 a6324a5507dbb169a8f46b057d4a42f9 351 Pfam PF14419 AF2226-like SPOUT RNA Methylase fused to THUMP 169 342 1.5E-81 T 23-10-2018 IPR025849 AF2226-like SPOUT RNA methylase fused to THUMP A3L01_03350 a6324a5507dbb169a8f46b057d4a42f9 351 Gene3D G3DSA:3.30.2130.30 1 150 5.1E-25 T 23-10-2018 A3L01_03350 a6324a5507dbb169a8f46b057d4a42f9 351 SUPERFAMILY SSF143437 2 147 4.88E-27 T 23-10-2018 A3L01_03350 a6324a5507dbb169a8f46b057d4a42f9 351 Pfam PF02926 THUMP domain 36 148 1.5E-29 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L01_03350 a6324a5507dbb169a8f46b057d4a42f9 351 SUPERFAMILY SSF75217 187 336 2.35E-18 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L01_04635 68a682c582231c87e692b6c1fead11b9 264 Gene3D G3DSA:3.40.50.300 1 246 5.3E-62 T 23-10-2018 A3L01_04635 68a682c582231c87e692b6c1fead11b9 264 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_04635 68a682c582231c87e692b6c1fead11b9 264 Pfam PF00005 ABC transporter 20 165 7.5E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_04635 68a682c582231c87e692b6c1fead11b9 264 SMART SM00382 28 215 2.0E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_04635 68a682c582231c87e692b6c1fead11b9 264 SUPERFAMILY SSF52540 3 228 8.84E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_07010 009e5ca5fcdadafc86e4e6d461660cea 326 Pfam PF00005 ABC transporter 31 181 9.8E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_07010 009e5ca5fcdadafc86e4e6d461660cea 326 Gene3D G3DSA:3.40.50.300 3 326 8.5E-102 T 23-10-2018 A3L01_07010 009e5ca5fcdadafc86e4e6d461660cea 326 SMART SM00382 39 238 3.4E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_07010 009e5ca5fcdadafc86e4e6d461660cea 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 300 5.4E-19 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L01_07010 009e5ca5fcdadafc86e4e6d461660cea 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 230 322 5.7E-28 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L01_07010 009e5ca5fcdadafc86e4e6d461660cea 326 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_07010 009e5ca5fcdadafc86e4e6d461660cea 326 SUPERFAMILY SSF52540 5 251 2.03E-76 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06820 8ffea42c2610e2f3749f9edfcbd97d48 169 Pfam PF00293 NUDIX domain 45 164 2.4E-24 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A3L01_06820 8ffea42c2610e2f3749f9edfcbd97d48 169 SUPERFAMILY SSF55811 32 166 2.84E-35 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A3L01_06820 8ffea42c2610e2f3749f9edfcbd97d48 169 Gene3D G3DSA:3.90.79.10 40 169 3.8E-43 T 23-10-2018 A3L01_06820 8ffea42c2610e2f3749f9edfcbd97d48 169 ProSitePatterns PS00893 Nudix box signature. 75 96 - T 23-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A3L01_06820 8ffea42c2610e2f3749f9edfcbd97d48 169 PRINTS PR00502 NUDIX hydrolase family signature 84 99 2.9E-8 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A3L01_06820 8ffea42c2610e2f3749f9edfcbd97d48 169 PRINTS PR00502 NUDIX hydrolase family signature 70 84 2.9E-8 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A3L01_07515 05fb7e0e43ad19ae83d6de43d357b36b 657 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 204 214 - T 23-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A3L01_07515 05fb7e0e43ad19ae83d6de43d357b36b 657 PRINTS PR00723 Subtilisin serine protease family (S8) signature 200 213 2.0E-22 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L01_07515 05fb7e0e43ad19ae83d6de43d357b36b 657 PRINTS PR00723 Subtilisin serine protease family (S8) signature 162 181 2.0E-22 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L01_07515 05fb7e0e43ad19ae83d6de43d357b36b 657 PRINTS PR00723 Subtilisin serine protease family (S8) signature 380 396 2.0E-22 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L01_07515 05fb7e0e43ad19ae83d6de43d357b36b 657 PIRSF PIRSF037907 1 657 0.0 T 23-10-2018 IPR017319 Subtilisin-like serine protease TK1689-type A3L01_07515 05fb7e0e43ad19ae83d6de43d357b36b 657 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 381 391 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A3L01_07515 05fb7e0e43ad19ae83d6de43d357b36b 657 Gene3D G3DSA:3.40.50.200 133 444 1.1E-141 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L01_07515 05fb7e0e43ad19ae83d6de43d357b36b 657 Gene3D G3DSA:2.60.120.380 557 653 1.1E-15 T 23-10-2018 A3L01_07515 05fb7e0e43ad19ae83d6de43d357b36b 657 Gene3D G3DSA:2.60.120.380 446 545 1.6E-22 T 23-10-2018 A3L01_07515 05fb7e0e43ad19ae83d6de43d357b36b 657 Gene3D G3DSA:3.30.70.80 40 132 4.3E-38 T 23-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A3L01_07515 05fb7e0e43ad19ae83d6de43d357b36b 657 SUPERFAMILY SSF49785 454 528 5.53E-5 T 23-10-2018 IPR008979 Galactose-binding-like domain superfamily A3L01_07515 05fb7e0e43ad19ae83d6de43d357b36b 657 Pfam PF00082 Subtilase family 162 432 1.0E-65 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A3L01_07515 05fb7e0e43ad19ae83d6de43d357b36b 657 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 167 178 - T 23-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A3L01_07515 05fb7e0e43ad19ae83d6de43d357b36b 657 SUPERFAMILY SSF52743 152 441 1.1E-91 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L01_07515 05fb7e0e43ad19ae83d6de43d357b36b 657 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 572 639 3.8E-8 T 23-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial A3L01_07565 e8e61987a13f4cb331e3376881a9eb52 298 Gene3D G3DSA:3.60.15.10 7 272 2.4E-15 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_07565 e8e61987a13f4cb331e3376881a9eb52 298 Pfam PF12706 Beta-lactamase superfamily domain 27 205 4.5E-7 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_07565 e8e61987a13f4cb331e3376881a9eb52 298 PIRSF PIRSF004944 1 298 1.1E-113 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase A3L01_07565 e8e61987a13f4cb331e3376881a9eb52 298 SUPERFAMILY SSF56281 1 262 1.02E-15 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_07565 e8e61987a13f4cb331e3376881a9eb52 298 Hamap MF_01406 UPF0282 protein . 1 285 38.955 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase A3L01_06055 4c22ee2e7177301e30b7d8100103fc22 253 SUPERFAMILY SSF51395 19 235 5.13E-47 T 23-10-2018 A3L01_06055 4c22ee2e7177301e30b7d8100103fc22 253 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 21 235 1.4E-77 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A3L01_06055 4c22ee2e7177301e30b7d8100103fc22 253 Pfam PF01884 PcrB family 16 238 3.5E-65 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A3L01_06055 4c22ee2e7177301e30b7d8100103fc22 253 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 15 247 35.266 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A3L01_06055 4c22ee2e7177301e30b7d8100103fc22 253 Gene3D G3DSA:3.20.20.390 5 252 6.5E-99 T 23-10-2018 IPR038597 GGGP/HepGP synthase superfamily A3L01_06055 4c22ee2e7177301e30b7d8100103fc22 253 TIGRFAM TIGR01769 GGGP: phosphoglycerol geranylgeranyltransferase 22 228 4.7E-83 T 23-10-2018 IPR010946 Geranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005737|GO:0006650|GO:0047294 KEGG: 00564+2.5.1.41|MetaCyc: PWY-6349 A3L01_05610 d58b10815e43e9bcbedaecbc0eb8271a 632 Gene3D G3DSA:2.120.10.30 149 321 5.9E-8 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A3L01_05610 d58b10815e43e9bcbedaecbc0eb8271a 632 SUPERFAMILY SSF53474 374 631 7.74E-70 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L01_05610 d58b10815e43e9bcbedaecbc0eb8271a 632 Pfam PF07676 WD40-like Beta Propeller Repeat 53 90 4.5E-7 T 23-10-2018 IPR011659 WD40-like Beta Propeller A3L01_05610 d58b10815e43e9bcbedaecbc0eb8271a 632 Gene3D G3DSA:2.120.10.30 23 143 2.6E-14 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A3L01_05610 d58b10815e43e9bcbedaecbc0eb8271a 632 SUPERFAMILY SSF82171 24 369 8.63E-30 T 23-10-2018 A3L01_05610 d58b10815e43e9bcbedaecbc0eb8271a 632 Gene3D G3DSA:3.40.50.1820 377 632 1.4E-71 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L01_05610 d58b10815e43e9bcbedaecbc0eb8271a 632 Pfam PF00326 Prolyl oligopeptidase family 421 631 5.3E-59 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A3L01_09920 01e7e76f94f63420295a5a80e8211b20 486 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 298 485 2.0E-28 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_09920 01e7e76f94f63420295a5a80e8211b20 486 Gene3D G3DSA:1.10.3720.10 270 485 7.1E-23 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_09920 01e7e76f94f63420295a5a80e8211b20 486 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 11 67 1.5E-5 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A3L01_09920 01e7e76f94f63420295a5a80e8211b20 486 SUPERFAMILY SSF161098 274 467 2.49E-24 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_07905 a171b1e8ecda4133be3594df58897803 88 Pfam PF13396 Phospholipase_D-nuclease N-terminal 24 65 3.6E-7 T 23-10-2018 IPR027379 Cardiolipin synthase N-terminal A3L01_06520 d31af999083fa988941f87233554b6de 112 SMART SM01022 6 109 7.3E-11 T 23-10-2018 IPR007374 ASCH domain A3L01_06520 d31af999083fa988941f87233554b6de 112 PIRSF PIRSF016134 2 111 6.8E-43 T 23-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 A3L01_06520 d31af999083fa988941f87233554b6de 112 Pfam PF04266 ASCH domain 7 107 1.0E-12 T 23-10-2018 IPR007374 ASCH domain A3L01_06520 d31af999083fa988941f87233554b6de 112 SUPERFAMILY SSF88697 1 108 6.76E-31 T 23-10-2018 IPR015947 PUA-like superfamily A3L01_06520 d31af999083fa988941f87233554b6de 112 Gene3D G3DSA:2.30.130.30 1 112 5.6E-40 T 23-10-2018 A3L01_09795 d9841eb9fc66a241dd517a371aa2fb02 140 Gene3D G3DSA:3.30.360.110 4 65 1.4E-18 T 23-10-2018 A3L01_09795 d9841eb9fc66a241dd517a371aa2fb02 140 SUPERFAMILY SSF56276 6 120 3.01E-42 T 23-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 A3L01_09795 d9841eb9fc66a241dd517a371aa2fb02 140 Gene3D G3DSA:3.30.160.750 66 128 4.6E-25 T 23-10-2018 A3L01_09795 d9841eb9fc66a241dd517a371aa2fb02 140 Pfam PF02675 S-adenosylmethionine decarboxylase 10 116 7.9E-38 T 23-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A3L01_09795 d9841eb9fc66a241dd517a371aa2fb02 140 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 6 116 1.8E-44 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A3L01_09795 d9841eb9fc66a241dd517a371aa2fb02 140 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 4 120 31.43 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A3L01_03060 bac69f76f0862ce2d9040e958be88bb6 153 Pfam PF10050 Predicted metal-binding protein (DUF2284) 8 138 2.4E-33 T 23-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding A3L01_03060 bac69f76f0862ce2d9040e958be88bb6 153 PIRSF PIRSF018748 1 153 5.3E-57 T 23-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding A3L01_01855 d3f77106d8f23fc04d840456fc63827c 65 Gene3D G3DSA:2.20.25.100 11 65 6.4E-25 T 23-10-2018 IPR023407 Ribosomal protein S27e, zinc-binding domain superfamily A3L01_01855 d3f77106d8f23fc04d840456fc63827c 65 Pfam PF01667 Ribosomal protein S27 11 64 2.3E-26 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01855 d3f77106d8f23fc04d840456fc63827c 65 ProSitePatterns PS01168 Ribosomal protein S27e signature. 19 51 - T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01855 d3f77106d8f23fc04d840456fc63827c 65 SUPERFAMILY SSF57829 11 65 3.66E-19 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L01_01855 d3f77106d8f23fc04d840456fc63827c 65 Hamap MF_00371 30S ribosomal protein S27e [rps27e]. 5 64 22.447 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06080 1e2426e6d476ddce9f3f5231d1031009 218 Gene3D G3DSA:1.10.10.580 147 216 3.1E-32 T 23-10-2018 IPR023093 ScpA-like, C-terminal A3L01_06080 1e2426e6d476ddce9f3f5231d1031009 218 Pfam PF02616 Segregation and condensation protein ScpA 18 163 2.7E-14 T 23-10-2018 IPR003768 Segregation and condensation protein A A3L01_01550 75c9978e56ed0bbb25f909916a0ee2e7 203 Gene3D G3DSA:3.60.20.10 3 203 3.8E-70 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L01_01550 75c9978e56ed0bbb25f909916a0ee2e7 203 PRINTS PR00141 Proteasome component signature 15 30 2.7E-9 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L01_01550 75c9978e56ed0bbb25f909916a0ee2e7 203 PRINTS PR00141 Proteasome component signature 171 182 2.7E-9 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L01_01550 75c9978e56ed0bbb25f909916a0ee2e7 203 PRINTS PR00141 Proteasome component signature 135 146 2.7E-9 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L01_01550 75c9978e56ed0bbb25f909916a0ee2e7 203 PRINTS PR00141 Proteasome component signature 146 157 2.7E-9 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L01_01550 75c9978e56ed0bbb25f909916a0ee2e7 203 Hamap MF_02113_A Proteasome subunit beta [prcB]. 3 197 35.737 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A3L01_01550 75c9978e56ed0bbb25f909916a0ee2e7 203 SUPERFAMILY SSF56235 5 202 3.05E-65 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L01_01550 75c9978e56ed0bbb25f909916a0ee2e7 203 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 7 190 2.4E-79 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A3L01_01550 75c9978e56ed0bbb25f909916a0ee2e7 203 Pfam PF00227 Proteasome subunit 6 185 1.1E-55 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L01_01550 75c9978e56ed0bbb25f909916a0ee2e7 203 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 11 58 - T 23-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L01_01135 536ea371965a93ec414a1fd040f11ffe 235 Hamap MF_01307_A 30S ribosomal protein S5 [rpsE]. 8 212 47.686 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01135 536ea371965a93ec414a1fd040f11ffe 235 Gene3D G3DSA:3.30.160.770 14 122 6.4E-37 T 23-10-2018 A3L01_01135 536ea371965a93ec414a1fd040f11ffe 235 Pfam PF03719 Ribosomal protein S5, C-terminal domain 145 210 2.6E-21 T 23-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 A3L01_01135 536ea371965a93ec414a1fd040f11ffe 235 Gene3D G3DSA:3.30.230.10 123 214 1.6E-29 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L01_01135 536ea371965a93ec414a1fd040f11ffe 235 SUPERFAMILY SSF54211 138 210 3.29E-19 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L01_01135 536ea371965a93ec414a1fd040f11ffe 235 Pfam PF00333 Ribosomal protein S5, N-terminal domain 62 123 2.3E-21 T 23-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 A3L01_01135 536ea371965a93ec414a1fd040f11ffe 235 SUPERFAMILY SSF54768 62 125 1.88E-18 T 23-10-2018 A3L01_01135 536ea371965a93ec414a1fd040f11ffe 235 TIGRFAM TIGR01020 uS5_euk_arch: ribosomal protein uS5 10 221 2.0E-105 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01135 536ea371965a93ec414a1fd040f11ffe 235 ProSitePatterns PS00585 Ribosomal protein S5 signature. 77 109 - T 23-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site A3L01_08555 d5e2d4359a80321f93da2b6bb9af9849 249 Pfam PF03099 Biotin/lipoate A/B protein ligase family 54 157 3.9E-12 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A3L01_08555 d5e2d4359a80321f93da2b6bb9af9849 249 Gene3D G3DSA:3.30.930.10 8 249 8.6E-61 T 23-10-2018 A3L01_08555 d5e2d4359a80321f93da2b6bb9af9849 249 SUPERFAMILY SSF55681 1 247 5.75E-68 T 23-10-2018 A3L01_02435 43fc31cbe473ceec878caac3d36728b2 381 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 368 2.8E-122 T 23-10-2018 IPR017439 Amidohydrolase GO:0016787 A3L01_02435 43fc31cbe473ceec878caac3d36728b2 381 Gene3D G3DSA:3.40.630.10 14 365 1.1E-145 T 23-10-2018 A3L01_02435 43fc31cbe473ceec878caac3d36728b2 381 Pfam PF07687 Peptidase dimerisation domain 184 275 3.3E-11 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A3L01_02435 43fc31cbe473ceec878caac3d36728b2 381 SUPERFAMILY SSF55031 177 284 1.44E-31 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A3L01_02435 43fc31cbe473ceec878caac3d36728b2 381 PIRSF PIRSF005962 1 381 8.3E-134 T 23-10-2018 IPR017439 Amidohydrolase GO:0016787 A3L01_02435 43fc31cbe473ceec878caac3d36728b2 381 Gene3D G3DSA:3.30.70.360 176 290 1.1E-145 T 23-10-2018 A3L01_02435 43fc31cbe473ceec878caac3d36728b2 381 Pfam PF01546 Peptidase family M20/M25/M40 68 371 8.3E-38 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A3L01_02435 43fc31cbe473ceec878caac3d36728b2 381 SUPERFAMILY SSF53187 6 380 4.57E-87 T 23-10-2018 A3L01_02655 9bcb7b709c42c55bac89b913e06c5ef8 421 SUPERFAMILY SSF50475 5 279 4.32E-63 T 23-10-2018 A3L01_02655 9bcb7b709c42c55bac89b913e06c5ef8 421 Gene3D G3DSA:3.40.1670.10 296 408 4.0E-37 T 23-10-2018 A3L01_02655 9bcb7b709c42c55bac89b913e06c5ef8 421 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 3 409 2.1E-113 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 A3L01_02655 9bcb7b709c42c55bac89b913e06c5ef8 421 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 7 385 6.6E-98 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 A3L01_02655 9bcb7b709c42c55bac89b913e06c5ef8 421 SUPERFAMILY SSF143968 282 419 1.83E-41 T 23-10-2018 A3L01_06855 6e39df9ddc8a4bc7f3cf2eb7405231f5 361 SUPERFAMILY SSF50331 236 356 1.97E-20 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L01_06855 6e39df9ddc8a4bc7f3cf2eb7405231f5 361 Gene3D G3DSA:2.40.50.100 239 355 3.2E-31 T 23-10-2018 A3L01_06855 6e39df9ddc8a4bc7f3cf2eb7405231f5 361 Gene3D G3DSA:3.40.50.300 1 237 1.1E-78 T 23-10-2018 A3L01_06855 6e39df9ddc8a4bc7f3cf2eb7405231f5 361 Gene3D G3DSA:2.40.50.140 281 341 3.2E-31 T 23-10-2018 A3L01_06855 6e39df9ddc8a4bc7f3cf2eb7405231f5 361 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_06855 6e39df9ddc8a4bc7f3cf2eb7405231f5 361 SUPERFAMILY SSF52540 4 243 1.17E-88 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06855 6e39df9ddc8a4bc7f3cf2eb7405231f5 361 Pfam PF00005 ABC transporter 19 161 9.6E-35 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_06855 6e39df9ddc8a4bc7f3cf2eb7405231f5 361 SMART SM00382 28 211 3.1E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_06855 6e39df9ddc8a4bc7f3cf2eb7405231f5 361 Pfam PF08402 TOBE domain 278 348 1.6E-6 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A3L01_00495 865d8fea20f52f5012e21501a55ebe15 276 Gene3D G3DSA:1.10.357.140 9 158 2.6E-16 T 23-10-2018 A3L01_00495 865d8fea20f52f5012e21501a55ebe15 276 Hamap MF_01286 Digeranylgeranylglyceryl phosphate synthase. 3 275 22.684 T 23-10-2018 IPR023547 Digeranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005886|GO:0008654|GO:0047295 KEGG: 00564+2.5.1.42|MetaCyc: PWY-6349 A3L01_00495 865d8fea20f52f5012e21501a55ebe15 276 Pfam PF01040 UbiA prenyltransferase family 23 256 1.7E-43 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A3L01_00495 865d8fea20f52f5012e21501a55ebe15 276 Gene3D G3DSA:1.20.120.1780 171 276 3.3E-5 T 23-10-2018 A3L01_01480 f9e92b2dca17ffceb8dc2d96e3a55edc 224 SUPERFAMILY SSF89550 15 220 2.0E-33 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L01_01480 f9e92b2dca17ffceb8dc2d96e3a55edc 224 Hamap MF_00756 Ribonuclease P protein component 3 [rnp3]. 13 224 23.587 T 23-10-2018 IPR023539 Ribonuclease P, protein component 3, archaeal GO:0001682|GO:0004526 A3L01_01480 f9e92b2dca17ffceb8dc2d96e3a55edc 224 Gene3D G3DSA:3.20.20.140 3 222 2.6E-100 T 23-10-2018 A3L01_01480 f9e92b2dca17ffceb8dc2d96e3a55edc 224 Pfam PF01876 RNase P subunit p30 24 212 4.5E-32 T 23-10-2018 IPR002738 RNase P subunit p30 GO:0004540|GO:0008033 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L01_01480 f9e92b2dca17ffceb8dc2d96e3a55edc 224 ProDom PD016938 P COMPONENT RIBONUCLEASE RNASE HYDROLASE PROCESSING TRNA SUBUNIT SIMILAR P/RNASE 119 211 8.0E-40 T 23-10-2018 A3L01_07995 ac07a2e9ea35703680e3097d15fb1f6a 261 SUPERFAMILY SSF51366 27 251 8.16E-27 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L01_07995 ac07a2e9ea35703680e3097d15fb1f6a 261 PIRSF PIRSF005956 1 259 4.0E-97 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A3L01_07995 ac07a2e9ea35703680e3097d15fb1f6a 261 TIGRFAM TIGR00259 thylakoid_BtpA: membrane complex biogenesis protein, BtpA family 6 256 6.8E-108 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A3L01_07995 ac07a2e9ea35703680e3097d15fb1f6a 261 ProDom PD011184 BTPA I PHOTOSYSTEM BIOGENESIS ASSEMBLY SGCQ TRIPHOSPHATASE NUCLEOSIDE PAE3553 ENZYME 28 197 4.0E-71 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A3L01_07995 ac07a2e9ea35703680e3097d15fb1f6a 261 Pfam PF03437 BtpA family 5 254 1.8E-106 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A3L01_02680 b8e408cf0245272addbe28c9742fd5bd 350 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 66 80 - T 23-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A3L01_02680 b8e408cf0245272addbe28c9742fd5bd 350 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 7 346 1.4E-178 T 23-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 A3L01_02680 b8e408cf0245272addbe28c9742fd5bd 350 SUPERFAMILY SSF50129 3 177 2.28E-53 T 23-10-2018 IPR011032 GroES-like superfamily A3L01_02680 b8e408cf0245272addbe28c9742fd5bd 350 Gene3D G3DSA:3.90.180.10 21 338 5.4E-133 T 23-10-2018 A3L01_02680 b8e408cf0245272addbe28c9742fd5bd 350 SMART SM00829 16 345 1.2E-5 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A3L01_02680 b8e408cf0245272addbe28c9742fd5bd 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 138 1.7E-35 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A3L01_02680 b8e408cf0245272addbe28c9742fd5bd 350 Gene3D G3DSA:3.40.50.720 157 291 5.4E-133 T 23-10-2018 A3L01_02680 b8e408cf0245272addbe28c9742fd5bd 350 Pfam PF00107 Zinc-binding dehydrogenase 178 306 1.3E-28 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A3L01_02680 b8e408cf0245272addbe28c9742fd5bd 350 SUPERFAMILY SSF51735 146 310 6.44E-34 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_02680 b8e408cf0245272addbe28c9742fd5bd 350 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 5 347 53.8 T 23-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 A3L01_04245 7b700791fd1d4e7e684136d5dc75ca1e 427 ProSitePatterns PS00455 Putative AMP-binding domain signature. 81 92 - T 23-10-2018 IPR020845 AMP-binding, conserved site A3L01_04245 7b700791fd1d4e7e684136d5dc75ca1e 427 SUPERFAMILY SSF56801 74 377 1.31E-24 T 23-10-2018 A3L01_04245 7b700791fd1d4e7e684136d5dc75ca1e 427 Pfam PF00501 AMP-binding enzyme 78 238 1.1E-12 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A3L01_04245 7b700791fd1d4e7e684136d5dc75ca1e 427 Gene3D G3DSA:3.40.50.12780 7 315 3.2E-27 T 23-10-2018 A3L01_02805 64d9c9bf8a6f9000dbd44d3625f72166 572 SMART SM00116 513 563 0.18 T 23-10-2018 IPR000644 CBS domain A3L01_02805 64d9c9bf8a6f9000dbd44d3625f72166 572 SMART SM00116 451 499 4.9E-7 T 23-10-2018 IPR000644 CBS domain A3L01_02805 64d9c9bf8a6f9000dbd44d3625f72166 572 Pfam PF00654 Voltage gated chloride channel 69 411 3.8E-86 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A3L01_02805 64d9c9bf8a6f9000dbd44d3625f72166 572 Gene3D G3DSA:3.10.580.10 432 497 9.6E-13 T 23-10-2018 A3L01_02805 64d9c9bf8a6f9000dbd44d3625f72166 572 Gene3D G3DSA:1.10.3080.10 2 431 1.0E-95 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 A3L01_02805 64d9c9bf8a6f9000dbd44d3625f72166 572 SUPERFAMILY SSF81340 6 431 7.85E-100 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 A3L01_02805 64d9c9bf8a6f9000dbd44d3625f72166 572 Gene3D G3DSA:3.10.580.10 498 563 6.0E-7 T 23-10-2018 A3L01_02805 64d9c9bf8a6f9000dbd44d3625f72166 572 Pfam PF00571 CBS domain 444 497 1.3E-11 T 23-10-2018 IPR000644 CBS domain A3L01_02805 64d9c9bf8a6f9000dbd44d3625f72166 572 Pfam PF00571 CBS domain 506 561 3.6E-7 T 23-10-2018 IPR000644 CBS domain A3L01_02805 64d9c9bf8a6f9000dbd44d3625f72166 572 SUPERFAMILY SSF54631 437 563 1.24E-25 T 23-10-2018 A3L01_02805 64d9c9bf8a6f9000dbd44d3625f72166 572 PRINTS PR00762 Chloride channel signature 81 98 2.1E-17 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A3L01_02805 64d9c9bf8a6f9000dbd44d3625f72166 572 PRINTS PR00762 Chloride channel signature 326 346 2.1E-17 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A3L01_02805 64d9c9bf8a6f9000dbd44d3625f72166 572 PRINTS PR00762 Chloride channel signature 161 180 2.1E-17 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A3L01_02805 64d9c9bf8a6f9000dbd44d3625f72166 572 PRINTS PR00762 Chloride channel signature 361 377 2.1E-17 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A3L01_05875 333684648da5010af8395355db19770b 459 Gene3D G3DSA:3.40.1190.20 12 446 1.2E-157 T 23-10-2018 IPR029056 Ribokinase-like A3L01_05875 333684648da5010af8395355db19770b 459 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 11 447 9.9E-110 T 23-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 A3L01_05875 333684648da5010af8395355db19770b 459 Gene3D G3DSA:3.30.1110.20 18 198 1.2E-157 T 23-10-2018 A3L01_05875 333684648da5010af8395355db19770b 459 PIRSF PIRSF015883 1 456 3.5E-198 T 23-10-2018 IPR015990 ADP-specific phosphofructokinase/glucokinase, archaeal GO:0000287|GO:0006096|GO:0016773 A3L01_05875 333684648da5010af8395355db19770b 459 SUPERFAMILY SSF53613 10 455 6.05E-155 T 23-10-2018 IPR029056 Ribokinase-like A3L01_05875 333684648da5010af8395355db19770b 459 Hamap MF_00561 ADP-specific phosphofructokinase [pfkC]. 4 456 44.418 T 23-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 A3L01_05875 333684648da5010af8395355db19770b 459 TIGRFAM TIGR02045 P_fruct_ADP: ADP-specific phosphofructokinase 11 456 2.2E-232 T 23-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 A3L01_02350 e5c3b23cc8dfaa07b25a9d57e7ee27c6 264 Pfam PF11495 Archaeal transcriptional regulator TrmB 126 262 1.1E-5 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal A3L01_02350 e5c3b23cc8dfaa07b25a9d57e7ee27c6 264 Gene3D G3DSA:3.30.870.10 122 264 4.1E-78 T 23-10-2018 A3L01_02350 e5c3b23cc8dfaa07b25a9d57e7ee27c6 264 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 77 1.7E-18 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L01_02350 e5c3b23cc8dfaa07b25a9d57e7ee27c6 264 SUPERFAMILY SSF46785 10 96 6.96E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_02350 e5c3b23cc8dfaa07b25a9d57e7ee27c6 264 Gene3D G3DSA:1.10.10.10 1 75 3.2E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_08875 d3615b0598cac1526e74fc3c44988485 401 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 382 401 1.0E-4 T 23-10-2018 IPR027552 CGP-CTERM domain A3L01_08875 d3615b0598cac1526e74fc3c44988485 401 TIGRFAM TIGR04292 heavy_Cys_CGP: heavy-Cys/CGP-CTERM domain protein 19 401 1.3E-157 T 23-10-2018 IPR027556 Heavy-Cys/GCP-CTERM domain protein A3L01_08875 d3615b0598cac1526e74fc3c44988485 401 TIGRFAM TIGR04289 heavy_Cys: eight-cysteine-cluster domain 143 196 5.0E-24 T 23-10-2018 IPR027553 Eight-cysteine-cluster domain A3L01_06715 44759b0fc6cd1e31a5d51f048689a6c1 316 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 31 55 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A3L01_06715 44759b0fc6cd1e31a5d51f048689a6c1 316 SUPERFAMILY SSF53613 2 301 5.46E-72 T 23-10-2018 IPR029056 Ribokinase-like A3L01_06715 44759b0fc6cd1e31a5d51f048689a6c1 316 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 240 253 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A3L01_06715 44759b0fc6cd1e31a5d51f048689a6c1 316 Gene3D G3DSA:3.40.1190.20 1 315 6.5E-103 T 23-10-2018 IPR029056 Ribokinase-like A3L01_06715 44759b0fc6cd1e31a5d51f048689a6c1 316 PRINTS PR00990 Ribokinase signature 26 45 6.0E-6 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L01_06715 44759b0fc6cd1e31a5d51f048689a6c1 316 PRINTS PR00990 Ribokinase signature 211 222 6.0E-6 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L01_06715 44759b0fc6cd1e31a5d51f048689a6c1 316 PRINTS PR00990 Ribokinase signature 178 193 6.0E-6 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L01_06715 44759b0fc6cd1e31a5d51f048689a6c1 316 Pfam PF00294 pfkB family carbohydrate kinase 2 293 2.9E-54 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A3L01_05905 fe2076610325948c7e052f959a0aad71 348 SUPERFAMILY SSF101821 68 177 2.29E-29 T 23-10-2018 A3L01_05905 fe2076610325948c7e052f959a0aad71 348 Gene3D G3DSA:3.40.630.10 6 336 1.6E-136 T 23-10-2018 A3L01_05905 fe2076610325948c7e052f959a0aad71 348 Pfam PF05343 M42 glutamyl aminopeptidase 45 335 2.4E-111 T 23-10-2018 IPR008007 Peptidase M42 A3L01_05905 fe2076610325948c7e052f959a0aad71 348 Gene3D G3DSA:2.40.30.40 68 161 1.6E-136 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A3L01_05905 fe2076610325948c7e052f959a0aad71 348 PIRSF PIRSF001123 1 347 1.0E-121 T 23-10-2018 IPR008007 Peptidase M42 A3L01_05905 fe2076610325948c7e052f959a0aad71 348 SUPERFAMILY SSF53187 5 343 3.47E-71 T 23-10-2018 A3L01_04545 f5903f885dc808e4f3024950a1d8900d 220 Pfam PF01863 Protein of unknown function DUF45 13 203 4.2E-45 T 23-10-2018 IPR002725 Protein of unknown function DUF45 A3L01_04545 f5903f885dc808e4f3024950a1d8900d 220 Gene3D G3DSA:3.30.2010.10 113 205 1.1E-18 T 23-10-2018 A3L01_08490 fb845dc65c78cf8bbe05202513043565 147 SUPERFAMILY SSF89915 17 120 4.32E-22 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 A3L01_08490 fb845dc65c78cf8bbe05202513043565 147 Pfam PF04545 Sigma-70, region 4 7 49 6.7E-7 T 23-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A3L01_08490 fb845dc65c78cf8bbe05202513043565 147 Gene3D G3DSA:3.30.1190.10 17 135 8.6E-36 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 A3L01_08490 fb845dc65c78cf8bbe05202513043565 147 PIRSF PIRSF004932 3 147 1.7E-64 T 23-10-2018 IPR018384 DNA-binding protein Tfx, euryarchaeota GO:0003677 A3L01_08490 fb845dc65c78cf8bbe05202513043565 147 TIGRFAM TIGR00721 tfx: DNA-binding protein, Tfx family 1 137 4.1E-56 T 23-10-2018 IPR004645 DNA-binding protein Tfx, archaea GO:0003677 A3L01_08490 fb845dc65c78cf8bbe05202513043565 147 Pfam PF14601 DNA_binding protein, TFX, C-term 52 132 1.5E-21 T 23-10-2018 IPR029291 DNA binding protein Tfx, C-terminal A3L01_03145 6f9d7d32f4402e0c5328b7bc1e19c0fd 199 Pfam PF06195 Protein of unknown function (DUF996) 38 176 5.8E-27 T 23-10-2018 IPR010397 Protein of unknown function DUF996 A3L01_10320 1f0471e67ec28b26dc239e2d1820846e 91 SUPERFAMILY SSF54984 9 91 4.32E-21 T 23-10-2018 IPR036219 Translation elongation factor eEF-1beta-like superfamily Reactome: R-HSA-156842 A3L01_10320 1f0471e67ec28b26dc239e2d1820846e 91 SMART SM00888 5 91 2.1E-31 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 A3L01_10320 1f0471e67ec28b26dc239e2d1820846e 91 TIGRFAM TIGR00489 aEF-1_beta: translation elongation factor aEF-1 beta 7 90 5.2E-22 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 A3L01_10320 1f0471e67ec28b26dc239e2d1820846e 91 Gene3D G3DSA:3.30.70.60 1 91 1.1E-34 T 23-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 A3L01_10320 1f0471e67ec28b26dc239e2d1820846e 91 Pfam PF00736 EF-1 guanine nucleotide exchange domain 9 91 9.7E-21 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 A3L01_10320 1f0471e67ec28b26dc239e2d1820846e 91 Hamap MF_00043 Elongation factor 1-beta [ef1b]. 1 91 40.307 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 A3L01_10320 1f0471e67ec28b26dc239e2d1820846e 91 PIRSF PIRSF006521 3 91 8.4E-32 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 A3L01_05460 3d526b1419cd9e1409461bf5c2ead980 68 Gene3D G3DSA:2.30.170.20 2 66 1.3E-27 T 23-10-2018 IPR038630 Ribosomal protein L24e/L24 superfamily A3L01_05460 3d526b1419cd9e1409461bf5c2ead980 68 ProSitePatterns PS01073 Ribosomal protein L24e signature. 9 26 - T 23-10-2018 IPR023442 Ribosomal protein L24e, conserved site A3L01_05460 3d526b1419cd9e1409461bf5c2ead980 68 SMART SM00746 7 45 2.2E-12 T 23-10-2018 IPR011017 TRASH domain A3L01_05460 3d526b1419cd9e1409461bf5c2ead980 68 SUPERFAMILY SSF57716 6 56 8.84E-21 T 23-10-2018 A3L01_05460 3d526b1419cd9e1409461bf5c2ead980 68 Pfam PF01246 Ribosomal protein L24e 3 60 2.7E-25 T 23-10-2018 IPR000988 Ribosomal protein L24e-related A3L01_05460 3d526b1419cd9e1409461bf5c2ead980 68 Hamap MF_00773 50S ribosomal protein L24e [rpl24e]. 2 55 27.423 T 23-10-2018 IPR023438 Ribosomal protein L24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_10310 d56285ee4dbec893559ddcadcf435046 460 Gene3D G3DSA:3.40.50.300 38 189 8.1E-9 T 23-10-2018 A3L01_10310 d56285ee4dbec893559ddcadcf435046 460 SUPERFAMILY SSF46785 252 328 2.96E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_10310 d56285ee4dbec893559ddcadcf435046 460 SMART SM00382 54 185 9.0E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_10310 d56285ee4dbec893559ddcadcf435046 460 Pfam PF13173 AAA domain 55 188 3.4E-24 T 23-10-2018 A3L01_10310 d56285ee4dbec893559ddcadcf435046 460 SUPERFAMILY SSF52540 37 205 2.42E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06425 5d0f7385f9001f6079f9a4ae9b3d4a95 150 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 91 101 - T 23-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 A3L01_06425 5d0f7385f9001f6079f9a4ae9b3d4a95 150 Pfam PF00782 Dual specificity phosphatase, catalytic domain 54 143 1.5E-15 T 23-10-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 A3L01_06425 5d0f7385f9001f6079f9a4ae9b3d4a95 150 Gene3D G3DSA:3.90.190.10 6 150 3.4E-33 T 23-10-2018 IPR029021 Protein-tyrosine phosphatase-like A3L01_06425 5d0f7385f9001f6079f9a4ae9b3d4a95 150 SMART SM00404 52 142 2.9E-4 T 23-10-2018 IPR003595 Protein-tyrosine phosphatase, catalytic A3L01_06425 5d0f7385f9001f6079f9a4ae9b3d4a95 150 SMART SM00195 4 146 3.5E-6 T 23-10-2018 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 A3L01_06425 5d0f7385f9001f6079f9a4ae9b3d4a95 150 SUPERFAMILY SSF52799 29 147 3.54E-34 T 23-10-2018 IPR029021 Protein-tyrosine phosphatase-like A3L01_05855 67df3b728c5a3450eb2b1911d7563be2 380 Gene3D G3DSA:3.30.70.1510 1 83 8.9E-33 T 23-10-2018 A3L01_05855 67df3b728c5a3450eb2b1911d7563be2 380 SUPERFAMILY SSF143437 1 175 1.74E-47 T 23-10-2018 A3L01_05855 67df3b728c5a3450eb2b1911d7563be2 380 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 177 368 1.9E-65 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 A3L01_05855 67df3b728c5a3450eb2b1911d7563be2 380 Gene3D G3DSA:3.40.50.620 177 374 1.9E-63 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_05855 67df3b728c5a3450eb2b1911d7563be2 380 SUPERFAMILY SSF52402 177 336 3.75E-50 T 23-10-2018 A3L01_05855 67df3b728c5a3450eb2b1911d7563be2 380 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 380 124.308 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 A3L01_05855 67df3b728c5a3450eb2b1911d7563be2 380 SMART SM00981 73 167 8.1E-20 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L01_05855 67df3b728c5a3450eb2b1911d7563be2 380 Pfam PF02926 THUMP domain 28 167 9.4E-26 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L01_05855 67df3b728c5a3450eb2b1911d7563be2 380 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 4 365 4.8E-103 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 A3L01_05855 67df3b728c5a3450eb2b1911d7563be2 380 Gene3D G3DSA:3.30.2300.10 84 165 3.0E-28 T 23-10-2018 A3L01_00955 ec6eea29dee188ebab22198eeb6209ea 461 SUPERFAMILY SSF52540 4 236 8.93E-32 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_00955 ec6eea29dee188ebab22198eeb6209ea 461 SUPERFAMILY SSF46785 237 315 1.98E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_00955 ec6eea29dee188ebab22198eeb6209ea 461 Pfam PF01637 ATPase domain predominantly from Archaea 6 197 5.1E-17 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L01_00955 ec6eea29dee188ebab22198eeb6209ea 461 Gene3D G3DSA:3.40.50.300 2 163 5.8E-29 T 23-10-2018 A3L01_00955 ec6eea29dee188ebab22198eeb6209ea 461 SUPERFAMILY SSF52980 338 398 3.93E-5 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L01_00955 ec6eea29dee188ebab22198eeb6209ea 461 Pfam PF03008 Archaea bacterial proteins of unknown function 306 405 8.9E-31 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L01_02980 dd044649c7250a11b5585d32c8d084a8 116 TIGRFAM TIGR02338 gimC_beta: prefoldin, beta subunit 4 112 3.8E-40 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 A3L01_02980 dd044649c7250a11b5585d32c8d084a8 116 Hamap MF_00307 Prefoldin subunit beta [pfdB]. 1 116 50.186 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 A3L01_02980 dd044649c7250a11b5585d32c8d084a8 116 SUPERFAMILY SSF46579 6 110 1.27E-22 T 23-10-2018 A3L01_02980 dd044649c7250a11b5585d32c8d084a8 116 Gene3D G3DSA:1.10.287.370 1 116 8.6E-40 T 23-10-2018 IPR009053 Prefoldin A3L01_02980 dd044649c7250a11b5585d32c8d084a8 116 Pfam PF01920 Prefoldin subunit 9 111 1.2E-23 T 23-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 A3L01_04875 eab3c1e819e931240c05c181759c5743 110 TIGRFAM TIGR01384 TFS_arch: transcription factor S 2 110 5.2E-39 T 23-10-2018 IPR006288 Transcription factor S GO:0006355 A3L01_04875 eab3c1e819e931240c05c181759c5743 110 Pfam PF01096 Transcription factor S-II (TFIIS) 70 107 9.5E-22 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 A3L01_04875 eab3c1e819e931240c05c181759c5743 110 SMART SM00440 69 108 1.8E-24 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 A3L01_04875 eab3c1e819e931240c05c181759c5743 110 ProSitePatterns PS01030 RNA polymerases M / 15 Kd subunits signature. 3 25 - T 23-10-2018 IPR019761 DNA-directed RNA polymerase M, 15kDa subunit, conserved site A3L01_04875 eab3c1e819e931240c05c181759c5743 110 SUPERFAMILY SSF57783 1 35 1.79E-6 T 23-10-2018 A3L01_04875 eab3c1e819e931240c05c181759c5743 110 Gene3D G3DSA:2.20.25.10 55 110 1.0E-28 T 23-10-2018 A3L01_04875 eab3c1e819e931240c05c181759c5743 110 PIRSF PIRSF005586 1 110 7.9E-39 T 23-10-2018 IPR012164 DNA-directed RNA polymerase subunit/transcription factor S GO:0006351 A3L01_04875 eab3c1e819e931240c05c181759c5743 110 SUPERFAMILY SSF57783 47 109 4.12E-24 T 23-10-2018 A3L01_04875 eab3c1e819e931240c05c181759c5743 110 ProSitePatterns PS00466 Zinc finger TFIIS-type signature. 71 106 - T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 A3L01_04875 eab3c1e819e931240c05c181759c5743 110 SMART SM00661 2 56 5.9E-15 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 A3L01_04875 eab3c1e819e931240c05c181759c5743 110 Pfam PF02150 RNA polymerases M/15 Kd subunit 1 33 2.8E-16 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 A3L01_04620 3bb11bb11b006a04ea1c88a538c16f27 232 SMART SM00322 126 193 6.6E-7 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L01_04620 3bb11bb11b006a04ea1c88a538c16f27 232 SMART SM00322 35 105 8.2E-11 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L01_04620 3bb11bb11b006a04ea1c88a538c16f27 232 SUPERFAMILY SSF54791 40 114 2.93E-13 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L01_04620 3bb11bb11b006a04ea1c88a538c16f27 232 Gene3D G3DSA:3.30.1370.10 35 117 9.2E-35 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L01_04620 3bb11bb11b006a04ea1c88a538c16f27 232 TIGRFAM TIGR03665 arCOG04150: arCOG04150 universal archaeal KH domain protein 41 215 4.8E-69 T 23-10-2018 IPR019964 KH domain protein, archaea A3L01_04620 3bb11bb11b006a04ea1c88a538c16f27 232 Pfam PF00013 KH domain 39 86 1.9E-9 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A3L01_04620 3bb11bb11b006a04ea1c88a538c16f27 232 Pfam PF00013 KH domain 142 189 5.2E-6 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A3L01_04620 3bb11bb11b006a04ea1c88a538c16f27 232 SUPERFAMILY SSF54791 134 204 4.24E-18 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L01_04620 3bb11bb11b006a04ea1c88a538c16f27 232 Gene3D G3DSA:3.30.1370.10 118 222 5.1E-33 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L01_01025 42544055e39dc4832902d7b90f751dd7 256 Pfam PF02598 Putative RNA methyltransferase 5 249 6.6E-51 T 23-10-2018 IPR003750 Putative RNA methyltransferase A3L01_01025 42544055e39dc4832902d7b90f751dd7 256 SUPERFAMILY SSF50249 91 156 3.94E-11 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_01025 42544055e39dc4832902d7b90f751dd7 256 Gene3D G3DSA:3.40.1280.10 5 252 6.9E-76 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L01_01025 42544055e39dc4832902d7b90f751dd7 256 Gene3D G3DSA:2.40.50.140 91 156 6.9E-76 T 23-10-2018 A3L01_01025 42544055e39dc4832902d7b90f751dd7 256 SUPERFAMILY SSF75217 4 254 3.27E-47 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L01_00880 60c6d121f42ffb0982be2e5cf80d1a50 170 SUPERFAMILY SSF56300 1 160 4.97E-39 T 23-10-2018 A3L01_00880 60c6d121f42ffb0982be2e5cf80d1a50 170 ProSitePatterns PS01269 Uncharacterized protein family UPF0025 signature. 108 132 - T 23-10-2018 IPR020935 Phosphodiesterase YfcE, conserved site A3L01_00880 60c6d121f42ffb0982be2e5cf80d1a50 170 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 151 1.0E-33 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L01_00880 60c6d121f42ffb0982be2e5cf80d1a50 170 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 155 2.9E-38 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A3L01_00880 60c6d121f42ffb0982be2e5cf80d1a50 170 Gene3D G3DSA:3.60.21.10 1 159 5.8E-51 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L01_01060 324e95b58d640600e514ce98b19992c3 210 Gene3D G3DSA:3.30.300.20 1 86 9.1E-30 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L01_01060 324e95b58d640600e514ce98b19992c3 210 SUPERFAMILY SSF54821 86 186 5.75E-26 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01060 324e95b58d640600e514ce98b19992c3 210 Gene3D G3DSA:3.30.1140.32 87 210 3.0E-42 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01060 324e95b58d640600e514ce98b19992c3 210 SUPERFAMILY SSF54814 7 93 1.28E-25 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L01_01060 324e95b58d640600e514ce98b19992c3 210 SMART SM00322 38 104 1.0E-7 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L01_01060 324e95b58d640600e514ce98b19992c3 210 Hamap MF_01309_A 30S ribosomal protein S3 [rpsC]. 2 197 42.613 T 23-10-2018 IPR027488 Ribosomal protein S3, archaeal GO:0003735|GO:0006412|GO:0015935 A3L01_01060 324e95b58d640600e514ce98b19992c3 210 Pfam PF00189 Ribosomal protein S3, C-terminal domain 99 182 4.8E-24 T 23-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01060 324e95b58d640600e514ce98b19992c3 210 TIGRFAM TIGR01008 uS3_euk_arch: ribosomal protein uS3 3 197 1.3E-94 T 23-10-2018 IPR005703 Ribosomal protein S3, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01060 324e95b58d640600e514ce98b19992c3 210 Pfam PF07650 KH domain 17 88 3.2E-16 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06250 6ae9585f75631f6d5dbf6a28d24ed0a9 341 Hamap MF_00614 Flap endonuclease 1 [fen]. 1 340 147.538 T 23-10-2018 IPR023426 Flap endonuclease 1 GO:0016788 Reactome: R-HSA-110362|Reactome: R-HSA-162594|Reactome: R-HSA-174437|Reactome: R-HSA-5651801|Reactome: R-HSA-5685939|Reactome: R-HSA-69166 A3L01_06250 6ae9585f75631f6d5dbf6a28d24ed0a9 341 SMART SM00485 1 101 6.1E-49 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 A3L01_06250 6ae9585f75631f6d5dbf6a28d24ed0a9 341 Gene3D G3DSA:1.10.150.20 221 281 3.9E-21 T 23-10-2018 A3L01_06250 6ae9585f75631f6d5dbf6a28d24ed0a9 341 Gene3D G3DSA:3.40.50.1010 1 220 6.4E-87 T 23-10-2018 A3L01_06250 6ae9585f75631f6d5dbf6a28d24ed0a9 341 SUPERFAMILY SSF88723 8 236 3.6E-65 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L01_06250 6ae9585f75631f6d5dbf6a28d24ed0a9 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 139 156 2.9E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L01_06250 6ae9585f75631f6d5dbf6a28d24ed0a9 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 21 35 2.9E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L01_06250 6ae9585f75631f6d5dbf6a28d24ed0a9 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 160 180 2.9E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L01_06250 6ae9585f75631f6d5dbf6a28d24ed0a9 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 226 241 2.9E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L01_06250 6ae9585f75631f6d5dbf6a28d24ed0a9 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 75 94 2.9E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L01_06250 6ae9585f75631f6d5dbf6a28d24ed0a9 341 SMART SM00279 223 257 1.5E-11 T 23-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 A3L01_06250 6ae9585f75631f6d5dbf6a28d24ed0a9 341 SUPERFAMILY SSF47807 221 339 3.44E-33 T 23-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily A3L01_06250 6ae9585f75631f6d5dbf6a28d24ed0a9 341 SMART SM00484 140 221 2.2E-37 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 A3L01_06250 6ae9585f75631f6d5dbf6a28d24ed0a9 341 TIGRFAM TIGR03674 fen_arch: flap structure-specific endonuclease 1 338 1.1E-156 T 23-10-2018 IPR019973 Flap structure-specific endonuclease, archaea GO:0016788 A3L01_06250 6ae9585f75631f6d5dbf6a28d24ed0a9 341 ProSitePatterns PS00841 XPG protein signature 1. 73 87 - T 23-10-2018 IPR019974 XPG conserved site GO:0016788 A3L01_06250 6ae9585f75631f6d5dbf6a28d24ed0a9 341 Pfam PF00752 XPG N-terminal domain 12 101 8.2E-22 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 A3L01_06250 6ae9585f75631f6d5dbf6a28d24ed0a9 341 Pfam PF00867 XPG I-region 141 236 2.0E-28 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 A3L01_07540 8f5a8580b4711c3e8f37025857ea1e02 69 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 8 63 1.4E-14 T 23-10-2018 A3L01_07540 8f5a8580b4711c3e8f37025857ea1e02 69 PRINTS PR00352 3Fe-4S ferredoxin signature 8 19 5.2E-6 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A3L01_07540 8f5a8580b4711c3e8f37025857ea1e02 69 PRINTS PR00352 3Fe-4S ferredoxin signature 19 29 5.2E-6 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A3L01_07540 8f5a8580b4711c3e8f37025857ea1e02 69 PRINTS PR00352 3Fe-4S ferredoxin signature 51 63 5.2E-6 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A3L01_07540 8f5a8580b4711c3e8f37025857ea1e02 69 SUPERFAMILY SSF54862 4 65 1.3E-11 T 23-10-2018 A3L01_07540 8f5a8580b4711c3e8f37025857ea1e02 69 Gene3D G3DSA:3.30.70.20 3 67 8.7E-17 T 23-10-2018 A3L01_04880 206d897f6a5bf1a7b2ed26c17399d8de 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 35 53 2.3E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L01_04880 206d897f6a5bf1a7b2ed26c17399d8de 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 57 81 2.3E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L01_04880 206d897f6a5bf1a7b2ed26c17399d8de 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 107 129 2.3E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L01_04880 206d897f6a5bf1a7b2ed26c17399d8de 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 195 209 2.3E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L01_04880 206d897f6a5bf1a7b2ed26c17399d8de 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 233 249 2.3E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L01_04880 206d897f6a5bf1a7b2ed26c17399d8de 249 SUPERFAMILY SSF55979 3 117 1.75E-33 T 23-10-2018 A3L01_04880 206d897f6a5bf1a7b2ed26c17399d8de 249 Gene3D G3DSA:3.70.10.10 2 242 4.3E-79 T 23-10-2018 A3L01_04880 206d897f6a5bf1a7b2ed26c17399d8de 249 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 35 58 - T 23-10-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L01_04880 206d897f6a5bf1a7b2ed26c17399d8de 249 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 4 116 4.8E-18 T 23-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L01_04880 206d897f6a5bf1a7b2ed26c17399d8de 249 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 3 247 32.882 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L01_04880 206d897f6a5bf1a7b2ed26c17399d8de 249 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 126 245 3.9E-10 T 23-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L01_04880 206d897f6a5bf1a7b2ed26c17399d8de 249 TIGRFAM TIGR00590 pcna: proliferating cell nuclear antigen (pcna) 3 249 1.3E-39 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L01_04880 206d897f6a5bf1a7b2ed26c17399d8de 249 SUPERFAMILY SSF55979 125 247 1.64E-31 T 23-10-2018 A3L01_01765 392abbbca8dd8b74e0179251f686eaaa 314 SMART SM00849 19 235 6.7E-5 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_01765 392abbbca8dd8b74e0179251f686eaaa 314 Pfam PF00753 Metallo-beta-lactamase superfamily 18 76 1.5E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_01765 392abbbca8dd8b74e0179251f686eaaa 314 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 3 294 6.1E-99 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 A3L01_01765 392abbbca8dd8b74e0179251f686eaaa 314 Hamap MF_01818 Ribonuclease BN [rbn]. 2 299 34.922 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 A3L01_01765 392abbbca8dd8b74e0179251f686eaaa 314 SUPERFAMILY SSF56281 3 299 1.76E-74 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_01765 392abbbca8dd8b74e0179251f686eaaa 314 Pfam PF12706 Beta-lactamase superfamily domain 197 263 1.5E-8 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_01765 392abbbca8dd8b74e0179251f686eaaa 314 Gene3D G3DSA:3.60.15.10 1 299 5.0E-83 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_00790 cd84128a859b292d8bc39dabf0fb93f2 236 Gene3D G3DSA:1.10.10.900 88 162 2.2E-30 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily A3L01_00790 cd84128a859b292d8bc39dabf0fb93f2 236 Gene3D G3DSA:3.30.1250.10 8 87 2.4E-31 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily A3L01_00790 cd84128a859b292d8bc39dabf0fb93f2 236 TIGRFAM TIGR00291 RNA_SBDS: rRNA metabolism protein, SBDS family 3 231 3.4E-92 T 23-10-2018 IPR002140 Ribosome maturation protein Sdo1/SBDS GO:0042256 A3L01_00790 cd84128a859b292d8bc39dabf0fb93f2 236 SUPERFAMILY SSF109728 82 155 2.88E-25 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily A3L01_00790 cd84128a859b292d8bc39dabf0fb93f2 236 ProSitePatterns PS01267 Uncharacterized protein family UPF0023 signature. 37 56 - T 23-10-2018 IPR018023 Ribosome maturation protein SBDS, conserved site A3L01_00790 cd84128a859b292d8bc39dabf0fb93f2 236 SUPERFAMILY SSF89895 4 87 3.14E-26 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily A3L01_00790 cd84128a859b292d8bc39dabf0fb93f2 236 Pfam PF09377 SBDS protein C-terminal domain 101 200 2.0E-16 T 23-10-2018 IPR018978 Ribosome maturation protein SBDS, C-terminal GO:0042254 A3L01_00790 cd84128a859b292d8bc39dabf0fb93f2 236 SUPERFAMILY SSF54980 157 228 1.68E-22 T 23-10-2018 IPR035647 EF-G domain III/V-like A3L01_00790 cd84128a859b292d8bc39dabf0fb93f2 236 Pfam PF01172 Shwachman-Bodian-Diamond syndrome (SBDS) protein 8 94 3.5E-26 T 23-10-2018 IPR019783 Ribosome maturation protein SBDS, N-terminal A3L01_00790 cd84128a859b292d8bc39dabf0fb93f2 236 Gene3D G3DSA:3.30.70.240 163 235 9.4E-29 T 23-10-2018 A3L01_04680 84dc06c3b115efc0e20ce6f39b3db5f9 223 Gene3D G3DSA:3.40.50.150 1 188 3.7E-56 T 23-10-2018 A3L01_04680 84dc06c3b115efc0e20ce6f39b3db5f9 223 SUPERFAMILY SSF53335 2 209 4.26E-53 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_04680 84dc06c3b115efc0e20ce6f39b3db5f9 223 Pfam PF08241 Methyltransferase domain 44 132 6.6E-28 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A3L01_04335 db0c0de178b2f211955ac7eb97ee9047 155 Gene3D G3DSA:3.30.70.640 1 155 2.2E-68 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L01_04335 db0c0de178b2f211955ac7eb97ee9047 155 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 138 4.7E-55 T 23-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L01_04335 db0c0de178b2f211955ac7eb97ee9047 155 SUPERFAMILY SSF55040 12 155 9.15E-52 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L01_04335 db0c0de178b2f211955ac7eb97ee9047 155 Pfam PF01967 MoaC family 14 154 1.5E-52 T 23-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L01_04335 db0c0de178b2f211955ac7eb97ee9047 155 Hamap MF_01224_A Cyclic pyranopterin monophosphate synthase [moaC]. 9 154 39.484 T 23-10-2018 IPR023047 Probable cyclic pyranopterin monophosphate synthase accessory protein, archaea KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823 A3L01_08010 4fe3c583cf62fc9ff0713970f719d81a 323 Gene3D G3DSA:1.10.8.300 206 315 2.2E-31 T 23-10-2018 A3L01_08010 4fe3c583cf62fc9ff0713970f719d81a 323 SUPERFAMILY SSF52540 7 290 2.84E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_08010 4fe3c583cf62fc9ff0713970f719d81a 323 PIRSF PIRSF002849 1 320 3.6E-125 T 23-10-2018 A3L01_08010 4fe3c583cf62fc9ff0713970f719d81a 323 Gene3D G3DSA:3.40.50.300 22 188 2.0E-44 T 23-10-2018 A3L01_08010 4fe3c583cf62fc9ff0713970f719d81a 323 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 42 171 8.7E-63 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A3L01_01915 ab2dc793be4f50a2aca547dc6e9964c0 422 Pfam PF04894 Archaeal Nre, N-terminal 20 285 5.1E-103 T 23-10-2018 IPR006978 Archaeal Nre, N-terminal A3L01_01915 ab2dc793be4f50a2aca547dc6e9964c0 422 Pfam PF04895 Archaeal Nre, C-terminal 297 407 8.1E-38 T 23-10-2018 IPR006979 Archaeal Nre, C-terminal A3L01_01915 ab2dc793be4f50a2aca547dc6e9964c0 422 Hamap MF_02096 DNA repair protein. 1 407 40.283 T 23-10-2018 IPR033167 Archaeal Nre GO:0006281 A3L01_04845 966b0076e438135d737ef9fe476728d4 237 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 193 7.9E-31 T 23-10-2018 A3L01_04845 966b0076e438135d737ef9fe476728d4 237 Gene3D G3DSA:1.10.150.520 16 94 6.5E-86 T 23-10-2018 A3L01_04845 966b0076e438135d737ef9fe476728d4 237 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 108 188 1.8E-13 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_04845 966b0076e438135d737ef9fe476728d4 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 175 8.4E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_04845 966b0076e438135d737ef9fe476728d4 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 106 119 8.4E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_04845 966b0076e438135d737ef9fe476728d4 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 137 153 8.4E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_04845 966b0076e438135d737ef9fe476728d4 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 8.4E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_04845 966b0076e438135d737ef9fe476728d4 237 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 127 193 6.7E-10 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_04845 966b0076e438135d737ef9fe476728d4 237 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 91 195 1.9E-13 T 23-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 A3L01_04845 966b0076e438135d737ef9fe476728d4 237 Gene3D G3DSA:3.40.50.1000 3 219 6.5E-86 T 23-10-2018 IPR023214 HAD superfamily A3L01_04845 966b0076e438135d737ef9fe476728d4 237 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 1 221 1.1E-86 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 A3L01_04845 966b0076e438135d737ef9fe476728d4 237 SUPERFAMILY SSF56784 1 225 2.23E-48 T 23-10-2018 IPR036412 HAD-like superfamily A3L01_00080 5eb79adc40b0a59bb79f07380ba67fcc 444 Pfam PF00156 Phosphoribosyl transferase domain 273 369 4.3E-7 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L01_00080 5eb79adc40b0a59bb79f07380ba67fcc 444 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 5 438 1.2E-160 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A3L01_00080 5eb79adc40b0a59bb79f07380ba67fcc 444 PIRSF PIRSF000485 1 441 1.3E-158 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A3L01_00080 5eb79adc40b0a59bb79f07380ba67fcc 444 Pfam PF13537 Glutamine amidotransferase domain 72 199 3.2E-18 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A3L01_00080 5eb79adc40b0a59bb79f07380ba67fcc 444 Gene3D G3DSA:3.40.50.2020 258 422 8.3E-145 T 23-10-2018 A3L01_00080 5eb79adc40b0a59bb79f07380ba67fcc 444 SUPERFAMILY SSF53271 233 439 1.23E-68 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L01_00080 5eb79adc40b0a59bb79f07380ba67fcc 444 SUPERFAMILY SSF56235 5 240 2.74E-54 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L01_00080 5eb79adc40b0a59bb79f07380ba67fcc 444 Gene3D G3DSA:3.60.20.10 5 438 8.3E-145 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L01_00080 5eb79adc40b0a59bb79f07380ba67fcc 444 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 4 437 44.823 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A3L01_07845 4f7b666f88ab1cf6463a7ccdf5e6044e 420 SMART SM00933 27 385 1.4E-26 T 23-10-2018 IPR018977 NurA domain A3L01_07845 4f7b666f88ab1cf6463a7ccdf5e6044e 420 PIRSF PIRSF018871 3 420 9.7E-117 T 23-10-2018 IPR016738 DNA double-strand break repair nuclease NurA-like A3L01_07845 4f7b666f88ab1cf6463a7ccdf5e6044e 420 Pfam PF09376 NurA domain 28 385 1.6E-70 T 23-10-2018 IPR018977 NurA domain A3L01_05785 d62aa5b23277305a5b373271668ab6b1 202 SUPERFAMILY SSF116726 108 191 1.7E-20 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L01_05785 d62aa5b23277305a5b373271668ab6b1 202 Pfam PF01895 PhoU domain 19 100 5.6E-9 T 23-10-2018 IPR026022 PhoU domain A3L01_05785 d62aa5b23277305a5b373271668ab6b1 202 Pfam PF02080 TrkA-C domain 125 191 3.5E-13 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A3L01_05785 d62aa5b23277305a5b373271668ab6b1 202 Gene3D G3DSA:1.20.58.220 8 116 2.5E-22 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L01_05785 d62aa5b23277305a5b373271668ab6b1 202 SUPERFAMILY SSF109755 12 127 2.62E-15 T 23-10-2018 A3L01_05785 d62aa5b23277305a5b373271668ab6b1 202 Gene3D G3DSA:3.30.70.1450 117 202 1.1E-23 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L01_06305 8bdcf10caaa42127783a37192372bd75 51 Hamap MF_00629 50S ribosomal protein L39e [rpl39e]. 1 51 18.928 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_06305 8bdcf10caaa42127783a37192372bd75 51 Pfam PF00832 Ribosomal L39 protein 9 50 3.3E-21 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_06305 8bdcf10caaa42127783a37192372bd75 51 SUPERFAMILY SSF48662 4 50 1.31E-18 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily A3L01_06305 8bdcf10caaa42127783a37192372bd75 51 Gene3D G3DSA:1.10.1620.10 2 51 7.2E-19 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily A3L01_02315 c8c7616cee5ba5844b3469bc34f9e380 107 TIGRFAM TIGR01878 cas_Csa5: CRISPR type I-A/APERN-associated protein Csa5 4 99 9.3E-31 T 23-10-2018 IPR010157 CRISPR type I-A/APERN-associated protein Csa5 A3L01_02315 c8c7616cee5ba5844b3469bc34f9e380 107 Gene3D G3DSA:1.20.120.1610 1 66 7.4E-20 T 23-10-2018 A3L01_02315 c8c7616cee5ba5844b3469bc34f9e380 107 Pfam PF09702 CRISPR-associated protein (Cas_Csa5) 5 99 1.3E-24 T 23-10-2018 IPR010157 CRISPR type I-A/APERN-associated protein Csa5 A3L01_00200 76314cf5aff8edeb8520eb174779d4b1 333 Pfam PF08608 Wyosine base formation 255 315 2.2E-22 T 23-10-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 A3L01_00200 76314cf5aff8edeb8520eb174779d4b1 333 TIGRFAM TIGR03972 rSAM_TYW1: wyosine biosynthesis protein TYW1 17 314 5.8E-128 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 A3L01_00200 76314cf5aff8edeb8520eb174779d4b1 333 SUPERFAMILY SSF102114 65 275 7.06E-16 T 23-10-2018 A3L01_00200 76314cf5aff8edeb8520eb174779d4b1 333 Gene3D G3DSA:3.20.20.70 2 333 2.8E-131 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_00200 76314cf5aff8edeb8520eb174779d4b1 333 Pfam PF04055 Radical SAM superfamily 67 252 1.5E-22 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L01_00200 76314cf5aff8edeb8520eb174779d4b1 333 Hamap MF_01921 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase [taw1]. 15 316 49.169 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 A3L01_02490 8ef126c7bb09c9fe1c94bcd354d98a98 268 SUPERFAMILY SSF56281 9 268 3.14E-32 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_02490 8ef126c7bb09c9fe1c94bcd354d98a98 268 SMART SM00849 21 239 1.4E-8 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_02490 8ef126c7bb09c9fe1c94bcd354d98a98 268 Pfam PF00753 Metallo-beta-lactamase superfamily 22 129 4.0E-15 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_02490 8ef126c7bb09c9fe1c94bcd354d98a98 268 Gene3D G3DSA:3.60.15.10 1 268 7.7E-75 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_07660 ba6a240b38fa77dcdb12ec044f93cc21 163 SUPERFAMILY SSF48452 13 93 8.43E-5 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_07660 ba6a240b38fa77dcdb12ec044f93cc21 163 Gene3D G3DSA:1.25.40.10 2 162 9.6E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_00115 dc0eb2301db2fb0c05d0994bde2eef0f 80 SUPERFAMILY SSF82697 3 78 1.38E-24 T 23-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L01_00115 dc0eb2301db2fb0c05d0994bde2eef0f 80 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 3 76 20.369 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L01_00115 dc0eb2301db2fb0c05d0994bde2eef0f 80 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 76 2.1E-26 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L01_00115 dc0eb2301db2fb0c05d0994bde2eef0f 80 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 77 6.0E-26 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L01_00115 dc0eb2301db2fb0c05d0994bde2eef0f 80 Gene3D G3DSA:3.30.1280.10 1 80 9.1E-29 T 23-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L01_00115 dc0eb2301db2fb0c05d0994bde2eef0f 80 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 77 2.6E-26 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L01_05155 58a8dea32205b1cdb2ebdc4e9dd8f0e9 240 Pfam PF02237 Biotin protein ligase C terminal domain 193 238 2.2E-5 T 23-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A3L01_05155 58a8dea32205b1cdb2ebdc4e9dd8f0e9 240 SUPERFAMILY SSF55681 8 177 2.56E-49 T 23-10-2018 A3L01_05155 58a8dea32205b1cdb2ebdc4e9dd8f0e9 240 SUPERFAMILY SSF50037 193 238 2.93E-7 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal A3L01_05155 58a8dea32205b1cdb2ebdc4e9dd8f0e9 240 Gene3D G3DSA:2.30.30.100 193 239 5.3E-10 T 23-10-2018 A3L01_05155 58a8dea32205b1cdb2ebdc4e9dd8f0e9 240 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 13 238 3.1E-55 T 23-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A3L01_05155 58a8dea32205b1cdb2ebdc4e9dd8f0e9 240 Pfam PF03099 Biotin/lipoate A/B protein ligase family 19 131 6.4E-18 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A3L01_05155 58a8dea32205b1cdb2ebdc4e9dd8f0e9 240 Gene3D G3DSA:3.30.930.10 11 188 6.0E-55 T 23-10-2018 A3L01_02585 48eb9b725788fcdb4a1da8d402229381 195 Gene3D G3DSA:2.40.50.140 66 154 1.4E-23 T 23-10-2018 A3L01_02585 48eb9b725788fcdb4a1da8d402229381 195 Hamap MF_00975 Exosome complex component Csl4 [csl4]. 12 192 28.222 T 23-10-2018 IPR030850 Exosome complex component Csl4, archaea GO:0000178|GO:0006396 A3L01_02585 48eb9b725788fcdb4a1da8d402229381 195 Pfam PF10447 Exosome component EXOSC1/CSL4 66 122 5.1E-5 T 23-10-2018 IPR019495 Exosome complex component CSL4, C-terminal GO:0000178|GO:0003723 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L01_02585 48eb9b725788fcdb4a1da8d402229381 195 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 12 48 2.4E-7 T 23-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L01_02585 48eb9b725788fcdb4a1da8d402229381 195 SUPERFAMILY SSF110324 11 63 4.81E-12 T 23-10-2018 A3L01_02585 48eb9b725788fcdb4a1da8d402229381 195 SMART SM00316 68 148 2.0E-8 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L01_02585 48eb9b725788fcdb4a1da8d402229381 195 SUPERFAMILY SSF50249 64 185 1.8E-29 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_02585 48eb9b725788fcdb4a1da8d402229381 195 Gene3D G3DSA:2.20.70.10 155 188 8.6E-17 T 23-10-2018 A3L01_02585 48eb9b725788fcdb4a1da8d402229381 195 Gene3D G3DSA:2.40.50.100 11 61 4.0E-16 T 23-10-2018 A3L01_09825 5b75c87b39af54d31fda9570dd780e83 162 Gene3D G3DSA:1.20.120.610 2 158 2.3E-40 T 23-10-2018 A3L01_09825 5b75c87b39af54d31fda9570dd780e83 162 SUPERFAMILY SSF81333 6 70 2.62E-10 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily A3L01_09825 5b75c87b39af54d31fda9570dd780e83 162 Pfam PF00137 ATP synthase subunit C 9 68 4.5E-12 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A3L01_09825 5b75c87b39af54d31fda9570dd780e83 162 Pfam PF00137 ATP synthase subunit C 97 155 1.6E-15 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A3L01_09825 5b75c87b39af54d31fda9570dd780e83 162 SUPERFAMILY SSF81333 89 156 6.93E-14 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily A3L01_09925 d7f5968a1bd757547e8fff8fa70c7c3e 319 SMART SM00382 34 240 2.6E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_09925 d7f5968a1bd757547e8fff8fa70c7c3e 319 Gene3D G3DSA:3.40.50.300 3 319 1.2E-104 T 23-10-2018 A3L01_09925 d7f5968a1bd757547e8fff8fa70c7c3e 319 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 298 3.6E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L01_09925 d7f5968a1bd757547e8fff8fa70c7c3e 319 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 5.4E-31 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L01_09925 d7f5968a1bd757547e8fff8fa70c7c3e 319 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_09925 d7f5968a1bd757547e8fff8fa70c7c3e 319 SUPERFAMILY SSF52540 5 254 1.24E-68 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_09925 d7f5968a1bd757547e8fff8fa70c7c3e 319 Pfam PF00005 ABC transporter 25 182 9.2E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_10200 36acdf67f4512ddd57351bb7dcfac5e5 340 Pfam PF14258 Domain of unknown function (DUF4350) 36 105 2.1E-9 T 23-10-2018 IPR025646 Domain of unknown function DUF4350 A3L01_01240 0cb1d119b0cc7a7a239fbcfb3607bf22 65 PIRSF PIRSF005653 1 65 1.8E-31 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L01_01240 0cb1d119b0cc7a7a239fbcfb3607bf22 65 Gene3D G3DSA:1.10.10.60 1 65 1.1E-32 T 23-10-2018 A3L01_01240 0cb1d119b0cc7a7a239fbcfb3607bf22 65 Hamap MF_00250 DNA-directed RNA polymerase subunit N [rpoN]. 1 63 23.725 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L01_01240 0cb1d119b0cc7a7a239fbcfb3607bf22 65 ProSitePatterns PS01112 RNA polymerases N / 8 Kd subunits signature. 2 11 - T 23-10-2018 IPR020789 RNA polymerases, subunit N, zinc binding site GO:0003677|GO:0003899|GO:0006351|GO:0008270 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L01_01240 0cb1d119b0cc7a7a239fbcfb3607bf22 65 Pfam PF01194 RNA polymerases N / 8 kDa subunit 2 58 3.8E-30 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L01_01240 0cb1d119b0cc7a7a239fbcfb3607bf22 65 ProDom PD006539 RNA POLYMERASE DNA-DIRECTED SUBUNIT TRANSFERASE NUCLEOTIDYLTRANSFERASE METAL-BINDING ZINC TRANSCRIPTION N 10 49 4.0E-14 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L01_01240 0cb1d119b0cc7a7a239fbcfb3607bf22 65 SUPERFAMILY SSF46924 2 63 2.22E-27 T 23-10-2018 IPR023580 RNA polymerase subunit RPB10 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L01_00865 201d5a3f019247ee54420ef009383f84 148 TIGRFAM TIGR00311 aIF-2beta: putative translation initiation factor aIF-2, beta subunit 15 147 4.8E-51 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 A3L01_00865 201d5a3f019247ee54420ef009383f84 148 Pfam PF01873 Domain found in IF2B/IF5 29 141 5.9E-36 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L01_00865 201d5a3f019247ee54420ef009383f84 148 SUPERFAMILY SSF100966 14 115 5.49E-27 T 23-10-2018 IPR016189 Translation initiation factor IF2/IF5, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L01_00865 201d5a3f019247ee54420ef009383f84 148 Gene3D G3DSA:3.30.70.3150 46 136 1.2E-31 T 23-10-2018 A3L01_00865 201d5a3f019247ee54420ef009383f84 148 Hamap MF_00232 Translation initiation factor 2 subunit beta [eif2b]. 14 148 33.196 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 A3L01_00865 201d5a3f019247ee54420ef009383f84 148 SMART SM00653 35 142 4.5E-58 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L01_00865 201d5a3f019247ee54420ef009383f84 148 SUPERFAMILY SSF75689 112 147 6.41E-12 T 23-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L01_00650 0e2fed3b8f82311ecd481df375ae1319 345 Pfam PF11536 Protein of unknown function (DUF3226) 103 337 8.4E-81 T 23-10-2018 IPR024508 Protein of unknown function DUF3226 A3L01_00650 0e2fed3b8f82311ecd481df375ae1319 345 SUPERFAMILY SSF160945 101 337 2.75E-86 T 23-10-2018 A3L01_00650 0e2fed3b8f82311ecd481df375ae1319 345 Gene3D G3DSA:1.10.3490.10 238 326 1.6E-66 T 23-10-2018 A3L01_00650 0e2fed3b8f82311ecd481df375ae1319 345 ProDom PD038575 MJECL12 PLASMID PH0156 102 325 1.0E-85 T 23-10-2018 IPR024508 Protein of unknown function DUF3226 A3L01_00650 0e2fed3b8f82311ecd481df375ae1319 345 Gene3D G3DSA:3.40.50.10620 101 327 1.6E-66 T 23-10-2018 A3L01_01720 090636ebb35a00efdaac0241834806fd 318 Gene3D G3DSA:2.120.10.30 71 296 7.1E-7 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A3L01_01720 090636ebb35a00efdaac0241834806fd 318 Pfam PF07676 WD40-like Beta Propeller Repeat 69 91 1.9E-4 T 23-10-2018 IPR011659 WD40-like Beta Propeller A3L01_01720 090636ebb35a00efdaac0241834806fd 318 Pfam PF07676 WD40-like Beta Propeller Repeat 225 248 0.28 T 23-10-2018 IPR011659 WD40-like Beta Propeller A3L01_01720 090636ebb35a00efdaac0241834806fd 318 SUPERFAMILY SSF82171 77 252 2.28E-10 T 23-10-2018 A3L01_05320 49b6eb87f0b709132f9a26053d75c066 118 Hamap MF_00674 UPF0251 protein . 14 111 23.505 T 23-10-2018 IPR002852 Uncharacterised protein family UPF0251 A3L01_05320 49b6eb87f0b709132f9a26053d75c066 118 Pfam PF02001 Protein of unknown function DUF134 13 102 6.5E-27 T 23-10-2018 IPR002852 Uncharacterised protein family UPF0251 A3L01_05320 49b6eb87f0b709132f9a26053d75c066 118 SUPERFAMILY SSF88659 48 95 7.1E-9 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A3L01_05320 49b6eb87f0b709132f9a26053d75c066 118 Gene3D G3DSA:1.10.10.10 47 96 2.8E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_02000 193d15812f8890fcb18de6cf5da8735d 446 PIRSF PIRSF006815 3 446 5.0E-158 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 A3L01_02000 193d15812f8890fcb18de6cf5da8735d 446 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 445 47.201 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 A3L01_02000 193d15812f8890fcb18de6cf5da8735d 446 Gene3D G3DSA:3.40.640.10 81 349 7.2E-152 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L01_02000 193d15812f8890fcb18de6cf5da8735d 446 Gene3D G3DSA:3.90.1150.10 70 442 7.2E-152 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L01_02000 193d15812f8890fcb18de6cf5da8735d 446 Pfam PF02347 Glycine cleavage system P-protein 3 442 5.4E-121 T 23-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A3L01_02000 193d15812f8890fcb18de6cf5da8735d 446 SUPERFAMILY SSF53383 3 445 6.77E-101 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L01_03085 ee9272f2279f2b395cee25e0b26fb5d0 197 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 176 195 6.5E-7 T 23-10-2018 IPR027552 CGP-CTERM domain A3L01_03085 ee9272f2279f2b395cee25e0b26fb5d0 197 SUPERFAMILY SSF52833 17 108 2.49E-11 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L01_03085 ee9272f2279f2b395cee25e0b26fb5d0 197 Gene3D G3DSA:3.40.30.10 13 117 1.3E-7 T 23-10-2018 A3L01_09695 6162e5a27477580115897e14af839eb8 246 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 4 37 8.1E-7 T 23-10-2018 IPR023833 Signal peptide, camelysin A3L01_09695 6162e5a27477580115897e14af839eb8 246 ProSitePatterns PS00018 EF-hand calcium-binding domain. 159 171 - T 23-10-2018 IPR018247 EF-Hand 1, calcium-binding site A3L01_03335 16a427746f45ec522e1bfccbc3da9c1a 475 Gene3D G3DSA:3.90.1640.30 4 219 8.9E-21 T 23-10-2018 A3L01_03335 16a427746f45ec522e1bfccbc3da9c1a 475 SUPERFAMILY SSF64182 7 470 2.83E-65 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L01_03335 16a427746f45ec522e1bfccbc3da9c1a 475 Gene3D G3DSA:3.10.310.30 335 469 3.1E-9 T 23-10-2018 A3L01_03335 16a427746f45ec522e1bfccbc3da9c1a 475 Pfam PF02272 DHHA1 domain 329 464 2.4E-21 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L01_00570 22c67bad1d1b91b9749a6382f2b31019 348 Gene3D G3DSA:3.60.70.12 1 347 1.9E-135 T 23-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A3L01_00570 22c67bad1d1b91b9749a6382f2b31019 348 Pfam PF03576 Peptidase family S58 19 326 9.9E-106 T 23-10-2018 IPR005321 Peptidase S58, DmpA A3L01_00570 22c67bad1d1b91b9749a6382f2b31019 348 SUPERFAMILY SSF56266 2 345 6.28E-99 T 23-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A3L01_03855 cdba63380893efe329918d6af4b28759 339 Gene3D G3DSA:2.40.30.40 70 164 1.9E-111 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A3L01_03855 cdba63380893efe329918d6af4b28759 339 PIRSF PIRSF001123 1 336 1.9E-36 T 23-10-2018 IPR008007 Peptidase M42 A3L01_03855 cdba63380893efe329918d6af4b28759 339 Gene3D G3DSA:3.40.630.10 11 333 1.9E-111 T 23-10-2018 A3L01_03855 cdba63380893efe329918d6af4b28759 339 SUPERFAMILY SSF101821 67 178 3.05E-26 T 23-10-2018 A3L01_03855 cdba63380893efe329918d6af4b28759 339 SUPERFAMILY SSF53187 2 334 8.46E-47 T 23-10-2018 A3L01_03855 cdba63380893efe329918d6af4b28759 339 Pfam PF05343 M42 glutamyl aminopeptidase 48 328 3.6E-70 T 23-10-2018 IPR008007 Peptidase M42 A3L01_08935 240fb7ef61d725da1e4ad9177d900846 88 Gene3D G3DSA:3.10.20.30 1 88 1.2E-29 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L01_08935 240fb7ef61d725da1e4ad9177d900846 88 Pfam PF02597 ThiS family 5 88 1.6E-22 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L01_08935 240fb7ef61d725da1e4ad9177d900846 88 SUPERFAMILY SSF54285 1 86 1.78E-25 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L01_08935 240fb7ef61d725da1e4ad9177d900846 88 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 3 88 2.8E-27 T 23-10-2018 IPR010038 MoaD, archaeal-type A3L01_06895 3f40bed4cefe8f10ad3c791af3e2f321 149 Gene3D G3DSA:3.40.50.620 2 149 1.2E-38 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_06895 3f40bed4cefe8f10ad3c791af3e2f321 149 Hamap MF_02115 FAD synthase [ribL]. 8 148 29.104 T 23-10-2018 IPR024902 FAD synthase RibL GO:0003919|GO:0006747|GO:0046444 KEGG: 00740+2.7.7.2|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L01_06895 3f40bed4cefe8f10ad3c791af3e2f321 149 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 9 75 6.9E-20 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L01_06895 3f40bed4cefe8f10ad3c791af3e2f321 149 Pfam PF01467 Cytidylyltransferase-like 11 142 1.4E-20 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L01_06895 3f40bed4cefe8f10ad3c791af3e2f321 149 SUPERFAMILY SSF52374 8 143 3.85E-26 T 23-10-2018 A3L01_02475 8462941c5e0184084548e96eac916b9e 130 ProSitePatterns PS01193 Ribosomal protein S8e signature. 10 29 - T 23-10-2018 IPR018283 Ribosomal protein S8e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_02475 8462941c5e0184084548e96eac916b9e 130 Gene3D G3DSA:2.40.10.310 61 130 1.0E-31 T 23-10-2018 A3L01_02475 8462941c5e0184084548e96eac916b9e 130 Pfam PF01201 Ribosomal protein S8e 2 125 1.9E-33 T 23-10-2018 IPR022309 Ribosomal protein S8e/ribosomal biogenesis NSA2 A3L01_02475 8462941c5e0184084548e96eac916b9e 130 TIGRFAM TIGR00307 eS8: ribosomal protein eS8 1 127 3.3E-47 T 23-10-2018 IPR001047 Ribosomal protein S8e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_02475 8462941c5e0184084548e96eac916b9e 130 Hamap MF_00029 30S ribosomal protein S8e [rps8e]. 2 126 32.035 T 23-10-2018 IPR020919 Ribosomal protein S8e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_04790 37fccc48ddacb938e09e2af8e7ce0f33 240 SUPERFAMILY SSF52540 1 221 1.67E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_04790 37fccc48ddacb938e09e2af8e7ce0f33 240 Gene3D G3DSA:3.40.50.300 2 230 1.0E-32 T 23-10-2018 A3L01_04790 37fccc48ddacb938e09e2af8e7ce0f33 240 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 11 217 3.4E-11 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L01_09410 f344aa82fe40b52d84b11f57281ab59a 509 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 342 477 1.2E-21 T 23-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A3L01_09410 f344aa82fe40b52d84b11f57281ab59a 509 Pfam PF01943 Polysaccharide biosynthesis protein 12 280 7.5E-30 T 23-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A3L01_02725 27cddf4113b5e44dd0fe98897b073869 98 Gene3D G3DSA:2.30.30.70 2 97 2.9E-36 T 23-10-2018 IPR036948 Ribosomal protein L21 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_02725 27cddf4113b5e44dd0fe98897b073869 98 Pfam PF01157 Ribosomal protein L21e 6 95 1.4E-31 T 23-10-2018 IPR001147 Ribosomal protein L21e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_02725 27cddf4113b5e44dd0fe98897b073869 98 Hamap MF_00369 50S ribosomal protein L21e [rpl21e]. 3 97 30.03 T 23-10-2018 IPR022856 Ribosomal protein L21e, archaeal A3L01_02725 27cddf4113b5e44dd0fe98897b073869 98 ProSitePatterns PS01171 Ribosomal protein L21e signature. 38 63 - T 23-10-2018 IPR018259 Ribosomal protein L21e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_02725 27cddf4113b5e44dd0fe98897b073869 98 SUPERFAMILY SSF50104 6 96 6.02E-31 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L01_09400 54d70fe8b0e6ab2a6b0ded1687218f48 382 Pfam PF00534 Glycosyl transferases group 1 199 363 6.5E-43 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L01_09400 54d70fe8b0e6ab2a6b0ded1687218f48 382 Gene3D G3DSA:3.40.50.2000 185 361 4.9E-80 T 23-10-2018 A3L01_09400 54d70fe8b0e6ab2a6b0ded1687218f48 382 Pfam PF13439 Glycosyltransferase Family 4 33 188 3.1E-22 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L01_09400 54d70fe8b0e6ab2a6b0ded1687218f48 382 SUPERFAMILY SSF53756 25 381 1.38E-87 T 23-10-2018 A3L01_09400 54d70fe8b0e6ab2a6b0ded1687218f48 382 Gene3D G3DSA:3.40.50.2000 39 377 4.9E-80 T 23-10-2018 A3L01_10130 fe377f8c58a4db2ba7f4c77f54fd2c8f 575 SUPERFAMILY SSF88713 5 228 3.0E-14 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L01_05455 e85a1421170f51f24f797cb9ee4a81cb 174 Gene3D G3DSA:3.30.70.141 1 159 7.8E-69 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L01_05455 e85a1421170f51f24f797cb9ee4a81cb 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 73 90 2.8E-42 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L01_05455 e85a1421170f51f24f797cb9ee4a81cb 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 53 72 2.8E-42 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L01_05455 e85a1421170f51f24f797cb9ee4a81cb 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 94 110 2.8E-42 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L01_05455 e85a1421170f51f24f797cb9ee4a81cb 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 9 31 2.8E-42 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L01_05455 e85a1421170f51f24f797cb9ee4a81cb 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 120 139 2.8E-42 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L01_05455 e85a1421170f51f24f797cb9ee4a81cb 174 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 120 128 - T 23-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L01_05455 e85a1421170f51f24f797cb9ee4a81cb 174 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 6 144 35.998 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L01_05455 e85a1421170f51f24f797cb9ee4a81cb 174 SUPERFAMILY SSF54919 6 152 5.63E-60 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L01_05455 e85a1421170f51f24f797cb9ee4a81cb 174 SMART SM00562 6 146 1.0E-81 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L01_05455 e85a1421170f51f24f797cb9ee4a81cb 174 Pfam PF00334 Nucleoside diphosphate kinase 7 143 1.2E-56 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L01_03165 024e5c5e600e5151e756411e09040603 196 SUPERFAMILY SSF56770 18 168 2.35E-50 T 23-10-2018 A3L01_03165 024e5c5e600e5151e756411e09040603 196 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 38 149 5.3E-18 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_03165 024e5c5e600e5151e756411e09040603 196 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 21 155 5.5E-44 T 23-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_03165 024e5c5e600e5151e756411e09040603 196 Gene3D G3DSA:3.40.50.12280 2 175 1.1E-51 T 23-10-2018 A3L01_06965 fe65b89816aa8b34c3a30348ec6e14b7 69 Pfam PF01381 Helix-turn-helix 5 58 3.0E-20 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L01_06965 fe65b89816aa8b34c3a30348ec6e14b7 69 SMART SM00530 4 59 4.2E-21 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L01_06965 fe65b89816aa8b34c3a30348ec6e14b7 69 SUPERFAMILY SSF47413 3 65 1.26E-20 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L01_06965 fe65b89816aa8b34c3a30348ec6e14b7 69 Gene3D G3DSA:1.10.260.40 1 64 2.2E-30 T 23-10-2018 A3L01_03975 d4891cb729ae7b46d8fb0822b0660eda 456 Pfam PF01554 MatE 17 177 2.0E-36 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L01_03975 d4891cb729ae7b46d8fb0822b0660eda 456 Pfam PF01554 MatE 241 407 3.0E-36 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L01_03975 d4891cb729ae7b46d8fb0822b0660eda 456 PIRSF PIRSF006603 6 456 2.4E-108 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L01_03975 d4891cb729ae7b46d8fb0822b0660eda 456 TIGRFAM TIGR00797 matE: MATE efflux family protein 17 419 3.4E-124 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L01_05160 5347540342811f637e615db7e5fdf7b3 281 SUPERFAMILY SSF51569 8 266 9.16E-69 T 23-10-2018 A3L01_05160 5347540342811f637e615db7e5fdf7b3 281 Pfam PF01791 DeoC/LacD family aldolase 24 251 6.3E-35 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L01_05160 5347540342811f637e615db7e5fdf7b3 281 SMART SM01133 23 251 4.0E-43 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L01_05160 5347540342811f637e615db7e5fdf7b3 281 PIRSF PIRSF038992 4 281 6.8E-90 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L01_05160 5347540342811f637e615db7e5fdf7b3 281 Gene3D G3DSA:3.20.20.70 2 279 4.7E-82 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_02790 a87457bfe110b37e6added2bbf645df2 321 SUPERFAMILY SSF56042 136 295 1.03E-39 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L01_02790 a87457bfe110b37e6added2bbf645df2 321 Gene3D G3DSA:3.90.650.10 138 308 1.5E-46 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L01_02790 a87457bfe110b37e6added2bbf645df2 321 Gene3D G3DSA:3.30.1330.10 1 137 7.7E-35 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L01_02790 a87457bfe110b37e6added2bbf645df2 321 Pfam PF00586 AIR synthase related protein, N-terminal domain 23 132 2.2E-18 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L01_02790 a87457bfe110b37e6added2bbf645df2 321 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 3 308 26.944 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A3L01_02790 a87457bfe110b37e6added2bbf645df2 321 SUPERFAMILY SSF55326 5 132 5.53E-32 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L01_02790 a87457bfe110b37e6added2bbf645df2 321 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 2 308 2.3E-85 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A3L01_02790 a87457bfe110b37e6added2bbf645df2 321 PIRSF PIRSF005303 1 308 5.5E-91 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A3L01_02790 a87457bfe110b37e6added2bbf645df2 321 Pfam PF02769 AIR synthase related protein, C-terminal domain 143 292 4.1E-11 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L01_00505 3d8b2e5374c66dcba7c1bdfe74689606 267 SUPERFAMILY SSF50249 36 131 2.06E-9 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_00505 3d8b2e5374c66dcba7c1bdfe74689606 267 Pfam PF01336 OB-fold nucleic acid binding domain 43 113 6.2E-9 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L01_00505 3d8b2e5374c66dcba7c1bdfe74689606 267 Gene3D G3DSA:2.40.50.140 21 141 2.1E-12 T 23-10-2018 A3L01_07655 436b55001bed61bb1e1cb4b76dd4f941 308 SMART SM00090 68 299 6.8E-80 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A3L01_07655 436b55001bed61bb1e1cb4b76dd4f941 308 Gene3D G3DSA:1.10.10.10 5 94 3.1E-16 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_07655 436b55001bed61bb1e1cb4b76dd4f941 308 Pfam PF09202 Rio2, N-terminal 13 92 1.7E-22 T 23-10-2018 IPR015285 RIO2 kinase winged helix domain, N-terminal GO:0004674|GO:0005524|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A3L01_07655 436b55001bed61bb1e1cb4b76dd4f941 308 SUPERFAMILY SSF46785 8 94 2.25E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_07655 436b55001bed61bb1e1cb4b76dd4f941 308 Gene3D G3DSA:1.10.510.10 202 297 3.2E-15 T 23-10-2018 A3L01_07655 436b55001bed61bb1e1cb4b76dd4f941 308 Pfam PF01163 RIO1 family 111 288 1.7E-47 T 23-10-2018 A3L01_07655 436b55001bed61bb1e1cb4b76dd4f941 308 Gene3D G3DSA:3.30.200.20 98 196 2.2E-24 T 23-10-2018 A3L01_07655 436b55001bed61bb1e1cb4b76dd4f941 308 SUPERFAMILY SSF56112 103 273 1.54E-24 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A3L01_09975 34c36b279980d850b7b90cc0b3b7deff 272 SUPERFAMILY SSF103481 173 265 2.88E-13 T 23-10-2018 A3L01_09975 34c36b279980d850b7b90cc0b3b7deff 272 SUPERFAMILY SSF103481 24 129 9.68E-16 T 23-10-2018 A3L01_09975 34c36b279980d850b7b90cc0b3b7deff 272 Pfam PF00892 EamA-like transporter family 1 126 2.2E-17 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L01_09975 34c36b279980d850b7b90cc0b3b7deff 272 Pfam PF00892 EamA-like transporter family 139 265 6.4E-19 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L01_06160 df878bcbe4bdb9748ee61c76bb050e8e 245 Gene3D G3DSA:3.40.50.300 3 243 2.9E-75 T 23-10-2018 A3L01_06160 df878bcbe4bdb9748ee61c76bb050e8e 245 Pfam PF00142 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family 157 234 1.1E-7 T 23-10-2018 IPR000392 NifH/frxC family GO:0005524|GO:0016491|GO:0055114 A3L01_06160 df878bcbe4bdb9748ee61c76bb050e8e 245 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 3 236 6.5E-100 T 23-10-2018 IPR010224 ATP binding protein MinD, archaea A3L01_06160 df878bcbe4bdb9748ee61c76bb050e8e 245 SUPERFAMILY SSF52540 1 235 1.89E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06160 df878bcbe4bdb9748ee61c76bb050e8e 245 PIRSF PIRSF003092 1 242 4.4E-57 T 23-10-2018 IPR025501 ATP binding protein MinD A3L01_06160 df878bcbe4bdb9748ee61c76bb050e8e 245 Pfam PF13614 AAA domain 3 145 1.3E-26 T 23-10-2018 IPR025669 AAA domain A3L01_07800 004f6b94909f9bdeae984fea4d6db959 495 Gene3D G3DSA:3.40.50.300 4 157 3.5E-35 T 23-10-2018 A3L01_07800 004f6b94909f9bdeae984fea4d6db959 495 SMART SM00382 42 159 7.2E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_07800 004f6b94909f9bdeae984fea4d6db959 495 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 46 155 2.2E-14 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L01_07800 004f6b94909f9bdeae984fea4d6db959 495 SUPERFAMILY SSF52540 4 212 2.37E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_07800 004f6b94909f9bdeae984fea4d6db959 495 Gene3D G3DSA:1.10.8.60 160 217 3.7E-11 T 23-10-2018 A3L01_07800 004f6b94909f9bdeae984fea4d6db959 495 Hamap MF_01508 Replication factor C large subunit [rfcL]. 4 427 34.04 T 23-10-2018 IPR023935 Replication factor C, large subunit A3L01_00565 ae0ca85a67465c814d9456b999e48613 541 Gene3D G3DSA:1.10.3720.10 5 265 7.3E-63 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_00565 ae0ca85a67465c814d9456b999e48613 541 Gene3D G3DSA:1.10.3720.10 289 540 2.2E-55 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_00565 ae0ca85a67465c814d9456b999e48613 541 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 371 531 2.1E-13 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_00565 ae0ca85a67465c814d9456b999e48613 541 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 254 4.1E-14 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_00565 ae0ca85a67465c814d9456b999e48613 541 SUPERFAMILY SSF161098 288 536 4.21E-55 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_00565 ae0ca85a67465c814d9456b999e48613 541 SUPERFAMILY SSF161098 5 258 4.36E-55 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_08325 6cc8f5771d94b630d8de9a1482af4662 375 PIRSF PIRSF015647 5 375 7.9E-192 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L01_08325 6cc8f5771d94b630d8de9a1482af4662 375 Pfam PF01950 Fructose-1,6-bisphosphatase 6 372 4.1E-188 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L01_08325 6cc8f5771d94b630d8de9a1482af4662 375 SUPERFAMILY SSF111249 6 372 3.14E-178 T 23-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L01_08325 6cc8f5771d94b630d8de9a1482af4662 375 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 5 372 61.844 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L01_08325 6cc8f5771d94b630d8de9a1482af4662 375 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 6 371 0.0 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L01_08840 e3ab4c53199fc68430089b178958f0c8 177 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 32 171 2.9E-12 T 23-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase A3L01_07115 f003e84d224a5ca5d455a29a8b548169 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 155 179 1.3E-6 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_07115 f003e84d224a5ca5d455a29a8b548169 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 307 326 1.3E-6 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_07115 f003e84d224a5ca5d455a29a8b548169 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 125 144 1.3E-6 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_07115 f003e84d224a5ca5d455a29a8b548169 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 224 248 1.3E-6 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_07115 f003e84d224a5ca5d455a29a8b548169 499 Pfam PF00361 Proton-conducting membrane transporter 120 390 2.7E-45 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_03715 4431ea6657c9f670fe51efb7fac4ba60 326 SUPERFAMILY SSF53807 24 288 1.62E-43 T 23-10-2018 A3L01_03715 4431ea6657c9f670fe51efb7fac4ba60 326 Gene3D G3DSA:3.40.50.1980 25 184 1.9E-29 T 23-10-2018 A3L01_03715 4431ea6657c9f670fe51efb7fac4ba60 326 Pfam PF01297 Zinc-uptake complex component A periplasmic 28 285 2.4E-31 T 23-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 A3L01_06275 fff553890cc16072efd4bcd6c4c98513 138 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 11 95 3.0E-35 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A3L01_06275 fff553890cc16072efd4bcd6c4c98513 138 SUPERFAMILY SSF75471 5 101 1.16E-17 T 23-10-2018 IPR035920 YhbY-like superfamily A3L01_06275 fff553890cc16072efd4bcd6c4c98513 138 SMART SM01103 5 92 3.7E-25 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A3L01_06275 fff553890cc16072efd4bcd6c4c98513 138 Gene3D G3DSA:3.30.110.60 5 112 2.8E-20 T 23-10-2018 IPR035920 YhbY-like superfamily A3L01_06275 fff553890cc16072efd4bcd6c4c98513 138 Pfam PF01985 CRS1 / YhbY (CRM) domain 5 92 5.2E-13 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A3L01_04980 b645dce69a150cef5193aaf43d5bc4c6 53 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 23-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 A3L01_04980 b645dce69a150cef5193aaf43d5bc4c6 53 Gene3D G3DSA:2.20.28.10 2 53 5.0E-29 T 23-10-2018 A3L01_04980 b645dce69a150cef5193aaf43d5bc4c6 53 PRINTS PR00163 Rubredoxin signature 33 49 5.9E-12 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 A3L01_04980 b645dce69a150cef5193aaf43d5bc4c6 53 PRINTS PR00163 Rubredoxin signature 3 19 5.9E-12 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 A3L01_04980 b645dce69a150cef5193aaf43d5bc4c6 53 SUPERFAMILY SSF57802 1 53 4.04E-25 T 23-10-2018 A3L01_04980 b645dce69a150cef5193aaf43d5bc4c6 53 Pfam PF00301 Rubredoxin 3 49 1.1E-25 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 A3L01_04980 b645dce69a150cef5193aaf43d5bc4c6 53 PIRSF PIRSF000071 1 53 9.6E-29 T 23-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 A3L01_09405 59b080a88fd5559d61d7128b83ac93c7 531 Gene3D G3DSA:3.40.720.10 423 501 2.7E-11 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L01_09405 59b080a88fd5559d61d7128b83ac93c7 531 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 6 416 1.9E-48 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A3L01_09405 59b080a88fd5559d61d7128b83ac93c7 531 Gene3D G3DSA:3.40.720.10 2 261 4.6E-54 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L01_09405 59b080a88fd5559d61d7128b83ac93c7 531 SUPERFAMILY SSF53649 5 471 1.37E-49 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L01_01145 0bd35824a8985dd36628922b5a49cf90 148 SUPERFAMILY SSF52080 5 147 3.01E-34 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily A3L01_01145 0bd35824a8985dd36628922b5a49cf90 148 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 29 146 1.8E-20 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P A3L01_01145 0bd35824a8985dd36628922b5a49cf90 148 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 1 148 14.473 T 23-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 A3L01_01145 0bd35824a8985dd36628922b5a49cf90 148 Gene3D G3DSA:4.10.990.10 4 52 1.4E-9 T 23-10-2018 IPR027386 50S ribosomal protein L15, N-terminal A3L01_01145 0bd35824a8985dd36628922b5a49cf90 148 ProSitePatterns PS00475 Ribosomal protein L15 signature. 112 142 - T 23-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01145 0bd35824a8985dd36628922b5a49cf90 148 Gene3D G3DSA:3.100.10.10 63 148 5.8E-24 T 23-10-2018 A3L01_07140 7878c37f2bb02dc56c9c54e4b10e3344 282 TIGRFAM TIGR00417 speE: spermidine synthase 10 274 3.4E-85 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L01_07140 7878c37f2bb02dc56c9c54e4b10e3344 282 Pfam PF17284 Spermidine synthase tetramerisation domain 10 60 3.7E-13 T 23-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L01_07140 7878c37f2bb02dc56c9c54e4b10e3344 282 Gene3D G3DSA:2.30.140.10 6 60 5.4E-24 T 23-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L01_07140 7878c37f2bb02dc56c9c54e4b10e3344 282 Pfam PF01564 Spermine/spermidine synthase domain 64 241 4.7E-54 T 23-10-2018 A3L01_07140 7878c37f2bb02dc56c9c54e4b10e3344 282 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 84 97 - T 23-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L01_07140 7878c37f2bb02dc56c9c54e4b10e3344 282 Gene3D G3DSA:3.40.50.150 62 282 6.4E-77 T 23-10-2018 A3L01_07140 7878c37f2bb02dc56c9c54e4b10e3344 282 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 8 280 36.863 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L01_07140 7878c37f2bb02dc56c9c54e4b10e3344 282 SUPERFAMILY SSF53335 9 280 4.96E-79 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_02305 93fa3dbc77f14e790eab12f0bec57a01 247 TIGRFAM TIGR01874 cas_cas5a: CRISPR-associated protein Cas5, subtype I-A/APERN 26 187 5.2E-12 T 23-10-2018 IPR010153 CRISPR-associated protein, Cas5a type A3L01_02305 93fa3dbc77f14e790eab12f0bec57a01 247 Gene3D G3DSA:3.30.70.3120 19 245 5.7E-15 T 23-10-2018 A3L01_04700 54a20765478f9f5454b7a1278eca5f8f 227 Pfam PF00406 Adenylate kinase 5 188 7.2E-41 T 23-10-2018 A3L01_04700 54a20765478f9f5454b7a1278eca5f8f 227 ProSitePatterns PS00113 Adenylate kinase signature. 79 90 - T 23-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L01_04700 54a20765478f9f5454b7a1278eca5f8f 227 TIGRFAM TIGR01351 adk: adenylate kinase 2 209 3.4E-72 T 23-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A3L01_04700 54a20765478f9f5454b7a1278eca5f8f 227 SUPERFAMILY SSF52540 1 212 8.63E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_04700 54a20765478f9f5454b7a1278eca5f8f 227 PRINTS PR00094 Adenylate kinase signature 79 95 3.1E-28 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L01_04700 54a20765478f9f5454b7a1278eca5f8f 227 PRINTS PR00094 Adenylate kinase signature 4 17 3.1E-28 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L01_04700 54a20765478f9f5454b7a1278eca5f8f 227 PRINTS PR00094 Adenylate kinase signature 158 173 3.1E-28 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L01_04700 54a20765478f9f5454b7a1278eca5f8f 227 PRINTS PR00094 Adenylate kinase signature 32 46 3.1E-28 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L01_04700 54a20765478f9f5454b7a1278eca5f8f 227 PRINTS PR00094 Adenylate kinase signature 175 189 3.1E-28 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L01_04700 54a20765478f9f5454b7a1278eca5f8f 227 Hamap MF_00235 Adenylate kinase [adk]. 1 211 45.209 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L01_04700 54a20765478f9f5454b7a1278eca5f8f 227 Gene3D G3DSA:3.40.50.300 1 217 7.3E-76 T 23-10-2018 A3L01_04700 54a20765478f9f5454b7a1278eca5f8f 227 Pfam PF05191 Adenylate kinase, active site lid 125 160 3.2E-17 T 23-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A3L01_03910 8bd87d45d1dda008e28fced3c20a7082 414 Pfam PF07690 Major Facilitator Superfamily 11 362 6.1E-29 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L01_03910 8bd87d45d1dda008e28fced3c20a7082 414 Gene3D G3DSA:1.20.1250.20 208 405 3.1E-12 T 23-10-2018 A3L01_03910 8bd87d45d1dda008e28fced3c20a7082 414 SUPERFAMILY SSF103473 4 404 3.66E-42 T 23-10-2018 IPR036259 MFS transporter superfamily A3L01_03910 8bd87d45d1dda008e28fced3c20a7082 414 PRINTS PR01988 Putative bacilysin exporter bacE signature 72 90 6.8E-5 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A3L01_03910 8bd87d45d1dda008e28fced3c20a7082 414 PRINTS PR01988 Putative bacilysin exporter bacE signature 46 64 6.8E-5 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A3L01_03910 8bd87d45d1dda008e28fced3c20a7082 414 PRINTS PR01988 Putative bacilysin exporter bacE signature 135 156 6.8E-5 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A3L01_03910 8bd87d45d1dda008e28fced3c20a7082 414 PRINTS PR01988 Putative bacilysin exporter bacE signature 162 179 6.8E-5 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A3L01_03910 8bd87d45d1dda008e28fced3c20a7082 414 Gene3D G3DSA:1.20.1250.20 2 187 9.1E-21 T 23-10-2018 A3L01_03910 8bd87d45d1dda008e28fced3c20a7082 414 TIGRFAM TIGR00900 2A0121: H+ Antiporter protein 7 373 3.4E-101 T 23-10-2018 IPR004751 Drug antiporter protein GO:0015307|GO:0015893 A3L01_07345 a63171b4e6a9b3c189d7a7061c9bb155 80 Pfam PF03683 Uncharacterised protein family (UPF0175) 18 75 7.0E-22 T 23-10-2018 IPR005368 Uncharacterised protein family UPF0175 A3L01_10110 c5c4f2c8792445719b34c3b9a8d5f830 1067 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 223 246 2.7E-29 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L01_10110 c5c4f2c8792445719b34c3b9a8d5f830 1067 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 42 53 2.7E-29 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L01_10110 c5c4f2c8792445719b34c3b9a8d5f830 1067 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 584 593 2.7E-29 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L01_10110 c5c4f2c8792445719b34c3b9a8d5f830 1067 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 545 558 2.7E-29 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L01_10110 c5c4f2c8792445719b34c3b9a8d5f830 1067 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 399 414 2.7E-29 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L01_10110 c5c4f2c8792445719b34c3b9a8d5f830 1067 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_10110 c5c4f2c8792445719b34c3b9a8d5f830 1067 Gene3D G3DSA:3.40.50.620 16 651 2.0E-229 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_10110 c5c4f2c8792445719b34c3b9a8d5f830 1067 SUPERFAMILY SSF50677 202 401 2.3E-53 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L01_10110 c5c4f2c8792445719b34c3b9a8d5f830 1067 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 9 876 0.0 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L01_10110 c5c4f2c8792445719b34c3b9a8d5f830 1067 SUPERFAMILY SSF47323 676 912 3.18E-61 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_10110 c5c4f2c8792445719b34c3b9a8d5f830 1067 Pfam PF08264 Anticodon-binding domain of tRNA 711 860 7.4E-38 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A3L01_10110 c5c4f2c8792445719b34c3b9a8d5f830 1067 Gene3D G3DSA:3.90.740.10 199 405 2.0E-229 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L01_10110 c5c4f2c8792445719b34c3b9a8d5f830 1067 SUPERFAMILY SSF47323 984 1050 8.5E-5 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_10110 c5c4f2c8792445719b34c3b9a8d5f830 1067 Gene3D G3DSA:1.10.730.10 669 853 1.8E-54 T 23-10-2018 A3L01_10110 c5c4f2c8792445719b34c3b9a8d5f830 1067 SUPERFAMILY SSF52374 2 674 1.64E-134 T 23-10-2018 A3L01_10110 c5c4f2c8792445719b34c3b9a8d5f830 1067 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 21 663 6.0E-186 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_10110 c5c4f2c8792445719b34c3b9a8d5f830 1067 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 3 1066 13.714 T 23-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L01_05430 685f0e3e2c50f5c3efadc12b2ad89268 334 Gene3D G3DSA:3.40.50.720 4 317 4.8E-141 T 23-10-2018 A3L01_05430 685f0e3e2c50f5c3efadc12b2ad89268 334 SUPERFAMILY SSF52283 2 133 1.25E-43 T 23-10-2018 A3L01_05430 685f0e3e2c50f5c3efadc12b2ad89268 334 SUPERFAMILY SSF51735 103 290 1.22E-63 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_05430 685f0e3e2c50f5c3efadc12b2ad89268 334 Gene3D G3DSA:3.40.50.720 98 290 4.8E-141 T 23-10-2018 A3L01_05430 685f0e3e2c50f5c3efadc12b2ad89268 334 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 290 3.5E-66 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A3L01_05430 685f0e3e2c50f5c3efadc12b2ad89268 334 Hamap MF_00776 Glyoxylate reductase [gyaR]. 1 331 59.792 T 23-10-2018 IPR023519 Glyoxylate reductase GyaR GO:0047964|GO:0055114 KEGG: 00630+1.1.1.26|MetaCyc: PWY-7294|MetaCyc: PWY-7295 A3L01_05430 685f0e3e2c50f5c3efadc12b2ad89268 334 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 322 3.5E-38 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A3L01_05430 685f0e3e2c50f5c3efadc12b2ad89268 334 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 230 246 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A3L01_09100 24e664423cb7aa7614865a7a18d4d701 242 TIGRFAM TIGR00161 TIGR00161: TIGR00161 family protein 10 235 1.5E-65 T 23-10-2018 IPR004425 Conserved hypothetical protein CHP00061 A3L01_09100 24e664423cb7aa7614865a7a18d4d701 242 SUPERFAMILY SSF159659 11 240 1.83E-49 T 23-10-2018 A3L01_09100 24e664423cb7aa7614865a7a18d4d701 242 Pfam PF09754 PAC2 family 19 222 8.1E-47 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 A3L01_09100 24e664423cb7aa7614865a7a18d4d701 242 Gene3D G3DSA:3.40.50.10900 1 242 9.5E-74 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily A3L01_09000 820d644c2ed8f9aca4acdb3854df6956 173 SMART SM00903 5 151 1.9E-19 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A3L01_09000 820d644c2ed8f9aca4acdb3854df6956 173 Gene3D G3DSA:2.30.110.10 1 164 7.0E-43 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A3L01_09000 820d644c2ed8f9aca4acdb3854df6956 173 Pfam PF01613 Flavin reductase like domain 8 140 8.5E-22 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A3L01_09000 820d644c2ed8f9aca4acdb3854df6956 173 SUPERFAMILY SSF50475 4 167 5.89E-37 T 23-10-2018 A3L01_00210 4aaca137b74d4288635b8118278094b8 195 Gene3D G3DSA:3.40.50.150 14 193 9.3E-37 T 23-10-2018 A3L01_00210 4aaca137b74d4288635b8118278094b8 195 SUPERFAMILY SSF53335 4 180 2.64E-37 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_00210 4aaca137b74d4288635b8118278094b8 195 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 15 189 2.0E-59 T 23-10-2018 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 A3L01_00210 4aaca137b74d4288635b8118278094b8 195 Pfam PF13847 Methyltransferase domain 37 153 1.9E-16 T 23-10-2018 IPR025714 Methyltransferase domain A3L01_02970 86ab7eea1307a84b987d417ea679929d 327 Gene3D G3DSA:3.10.310.40 220 323 2.0E-6 T 23-10-2018 A3L01_02970 86ab7eea1307a84b987d417ea679929d 327 Pfam PF02272 DHHA1 domain 234 317 7.5E-12 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L01_02970 86ab7eea1307a84b987d417ea679929d 327 SUPERFAMILY SSF64182 17 306 5.62E-51 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L01_02970 86ab7eea1307a84b987d417ea679929d 327 Gene3D G3DSA:3.90.1640.10 6 196 8.2E-38 T 23-10-2018 A3L01_02970 86ab7eea1307a84b987d417ea679929d 327 Pfam PF01368 DHH family 19 159 1.1E-10 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A3L01_09290 2ee7d7de169b5c552c30bf709db17018 408 Pfam PF01882 Protein of unknown function DUF58 188 267 1.8E-22 T 23-10-2018 IPR002881 Domain of unknown function DUF58 A3L01_00805 e7d5847d26f26380c1768bf3492197c7 269 Pfam PF03725 3' exoribonuclease family, domain 2 190 253 1.6E-13 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L01_00805 e7d5847d26f26380c1768bf3492197c7 269 Pfam PF01138 3' exoribonuclease family, domain 1 30 164 1.2E-26 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L01_00805 e7d5847d26f26380c1768bf3492197c7 269 Gene3D G3DSA:3.30.230.70 1 268 2.7E-86 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L01_00805 e7d5847d26f26380c1768bf3492197c7 269 Hamap MF_00622 Exosome complex component Rrp42 [rrp42]. 1 265 45.199 T 23-10-2018 IPR020869 Exosome complex component Rrp42, archaea GO:0000178|GO:0006401 A3L01_00805 e7d5847d26f26380c1768bf3492197c7 269 SUPERFAMILY SSF54211 9 212 2.13E-52 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L01_00805 e7d5847d26f26380c1768bf3492197c7 269 SUPERFAMILY SSF55666 184 266 1.54E-23 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L01_01895 ad81a920cdbcf3941b8af36c9210e235 399 Gene3D G3DSA:3.90.1150.10 24 390 4.9E-142 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L01_01895 ad81a920cdbcf3941b8af36c9210e235 399 Pfam PF00155 Aminotransferase class I and II 31 381 1.0E-60 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L01_01895 ad81a920cdbcf3941b8af36c9210e235 399 Gene3D G3DSA:3.40.640.10 53 294 4.9E-142 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L01_01895 ad81a920cdbcf3941b8af36c9210e235 399 SUPERFAMILY SSF53383 12 394 5.72E-106 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L01_03935 5b899e27373e62bcaab24a507ebb0ab9 334 SUPERFAMILY SSF51735 3 158 1.73E-47 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_03935 5b899e27373e62bcaab24a507ebb0ab9 334 Gene3D G3DSA:3.30.360.10 140 301 5.7E-149 T 23-10-2018 A3L01_03935 5b899e27373e62bcaab24a507ebb0ab9 334 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 118 2.5E-13 T 23-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A3L01_03935 5b899e27373e62bcaab24a507ebb0ab9 334 Gene3D G3DSA:3.40.50.720 3 331 5.7E-149 T 23-10-2018 A3L01_03935 5b899e27373e62bcaab24a507ebb0ab9 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 146 296 2.0E-30 T 23-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_03935 5b899e27373e62bcaab24a507ebb0ab9 334 TIGRFAM TIGR01546 GAPDH-II_archae: glyceraldehyde-3-phosphate dehydrogenase, type II 5 333 1.3E-181 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 A3L01_03935 5b899e27373e62bcaab24a507ebb0ab9 334 SMART SM00846 3 141 6.0E-19 T 23-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_03935 5b899e27373e62bcaab24a507ebb0ab9 334 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 139 146 - T 23-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_03935 5b899e27373e62bcaab24a507ebb0ab9 334 PIRSF PIRSF000149 1 318 1.7E-86 T 23-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_03935 5b899e27373e62bcaab24a507ebb0ab9 334 SUPERFAMILY SSF55347 140 301 8.69E-52 T 23-10-2018 A3L01_03935 5b899e27373e62bcaab24a507ebb0ab9 334 Hamap MF_00559 Glyceraldehyde-3-phosphate dehydrogenase [gap]. 1 334 190.196 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 A3L01_08345 e5d15a288e1649b0c8027fc03e1a7807 416 Gene3D G3DSA:3.50.50.60 124 258 1.0E-55 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_08345 e5d15a288e1649b0c8027fc03e1a7807 416 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 4.0E-17 T 23-10-2018 A3L01_08345 e5d15a288e1649b0c8027fc03e1a7807 416 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 184 4.0E-17 T 23-10-2018 A3L01_08345 e5d15a288e1649b0c8027fc03e1a7807 416 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 251 265 4.0E-17 T 23-10-2018 A3L01_08345 e5d15a288e1649b0c8027fc03e1a7807 416 Gene3D G3DSA:3.50.50.60 5 299 1.0E-55 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_08345 e5d15a288e1649b0c8027fc03e1a7807 416 SUPERFAMILY SSF51905 5 342 1.27E-46 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_08345 e5d15a288e1649b0c8027fc03e1a7807 416 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 266 9.9E-25 T 23-10-2018 A3L01_08345 e5d15a288e1649b0c8027fc03e1a7807 416 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 9.9E-25 T 23-10-2018 A3L01_08345 e5d15a288e1649b0c8027fc03e1a7807 416 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 278 300 9.9E-25 T 23-10-2018 A3L01_08345 e5d15a288e1649b0c8027fc03e1a7807 416 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 9.9E-25 T 23-10-2018 A3L01_08345 e5d15a288e1649b0c8027fc03e1a7807 416 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 9.9E-25 T 23-10-2018 A3L01_08345 e5d15a288e1649b0c8027fc03e1a7807 416 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 300 4.1E-37 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L01_09555 1ef3882ae1bd2464fe2122587e5c7d01 140 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 5 124 1.6E-25 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L01_09555 1ef3882ae1bd2464fe2122587e5c7d01 140 Gene3D G3DSA:3.40.50.11570 2 138 3.1E-21 T 23-10-2018 A3L01_03115 da2de3096ab884aff0c84791290b0268 446 SUPERFAMILY SSF55785 324 422 5.58E-9 T 23-10-2018 IPR035965 PAS domain superfamily A3L01_03115 da2de3096ab884aff0c84791290b0268 446 Gene3D G3DSA:3.30.450.20 307 442 4.6E-46 T 23-10-2018 A3L01_03115 da2de3096ab884aff0c84791290b0268 446 Pfam PF04282 Family of unknown function (DUF438) 15 79 3.6E-23 T 23-10-2018 IPR007380 Domain of unknown function DUF438 A3L01_03115 da2de3096ab884aff0c84791290b0268 446 Pfam PF01814 Hemerythrin HHE cation binding domain 99 233 6.6E-17 T 23-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 A3L01_03115 da2de3096ab884aff0c84791290b0268 446 Gene3D G3DSA:1.20.120.520 87 306 1.7E-53 T 23-10-2018 A3L01_03115 da2de3096ab884aff0c84791290b0268 446 Pfam PF13596 PAS domain 326 430 2.7E-23 T 23-10-2018 A3L01_06000 e3b44ff5450ba314c6c0d1a92d2e6e19 145 Gene3D G3DSA:3.40.50.1010 3 140 1.1E-5 T 23-10-2018 A3L01_06000 e3b44ff5450ba314c6c0d1a92d2e6e19 145 Pfam PF01850 PIN domain 4 129 1.1E-13 T 23-10-2018 IPR002716 PIN domain A3L01_06000 e3b44ff5450ba314c6c0d1a92d2e6e19 145 SMART SM00670 2 127 9.1E-6 T 23-10-2018 IPR002716 PIN domain A3L01_06000 e3b44ff5450ba314c6c0d1a92d2e6e19 145 SUPERFAMILY SSF88723 1 130 1.74E-16 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L01_04265 d874d6b0d645a7ed49b6916bfbd9a573 424 Hamap MF_01892 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS [tiaS]. 3 422 36.692 T 23-10-2018 IPR024913 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS GO:0002101|GO:0016879 A3L01_04265 d874d6b0d645a7ed49b6916bfbd9a573 424 Pfam PF01336 OB-fold nucleic acid binding domain 270 341 9.2E-9 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L01_04265 d874d6b0d645a7ed49b6916bfbd9a573 424 Gene3D G3DSA:3.30.70.2200 1 155 3.9E-61 T 23-10-2018 A3L01_04265 d874d6b0d645a7ed49b6916bfbd9a573 424 Gene3D G3DSA:2.40.50.1010 252 401 7.4E-43 T 23-10-2018 A3L01_04265 d874d6b0d645a7ed49b6916bfbd9a573 424 Gene3D G3DSA:3.90.600.20 156 251 1.7E-34 T 23-10-2018 A3L01_04265 d874d6b0d645a7ed49b6916bfbd9a573 424 Pfam PF08489 Domain of unknown function (DUF1743) 140 253 3.0E-38 T 23-10-2018 IPR013696 Domain of unknown function DUF1743 A3L01_00245 66e1f0b0dc26ba97ffc7a298d3cfde72 186 SUPERFAMILY SSF50249 80 179 2.83E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_00245 66e1f0b0dc26ba97ffc7a298d3cfde72 186 Gene3D G3DSA:3.30.1490.120 1 81 1.6E-32 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 A3L01_00245 66e1f0b0dc26ba97ffc7a298d3cfde72 186 Pfam PF00575 S1 RNA binding domain 78 150 1.1E-15 T 23-10-2018 IPR003029 S1 domain GO:0003676 A3L01_00245 66e1f0b0dc26ba97ffc7a298d3cfde72 186 TIGRFAM TIGR00448 rpoE: DNA-directed RNA polymerase 1 179 3.1E-69 T 23-10-2018 IPR004519 DNA-directed RNA polymerase, subunit E/RPC8 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 A3L01_00245 66e1f0b0dc26ba97ffc7a298d3cfde72 186 SMART SM00316 80 166 7.2E-18 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L01_00245 66e1f0b0dc26ba97ffc7a298d3cfde72 186 SUPERFAMILY SSF88798 1 78 1.7E-21 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 A3L01_00245 66e1f0b0dc26ba97ffc7a298d3cfde72 186 Gene3D G3DSA:2.40.50.140 82 186 5.2E-33 T 23-10-2018 A3L01_00245 66e1f0b0dc26ba97ffc7a298d3cfde72 186 Pfam PF03876 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 8 77 9.7E-19 T 23-10-2018 IPR005576 RNA polymerase Rpb7, N-terminal GO:0003899|GO:0006351 A3L01_02785 52d951fa8ffaad0dc92bb4c12a966167 293 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 10 274 3.7E-40 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L01_02785 52d951fa8ffaad0dc92bb4c12a966167 293 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 10 280 1.2E-36 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L01_01170 9c60f2645a46a447583ae1bd39fbd14a 193 Pfam PF13189 Cytidylate kinase-like family 7 160 2.9E-24 T 23-10-2018 A3L01_01170 9c60f2645a46a447583ae1bd39fbd14a 193 Gene3D G3DSA:3.40.50.300 2 177 2.4E-44 T 23-10-2018 A3L01_01170 9c60f2645a46a447583ae1bd39fbd14a 193 Hamap MF_00239 Cytidylate kinase [cmk]. 6 178 47.433 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A3L01_01170 9c60f2645a46a447583ae1bd39fbd14a 193 SUPERFAMILY SSF52540 3 176 7.91E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_01170 9c60f2645a46a447583ae1bd39fbd14a 193 TIGRFAM TIGR02173 cyt_kin_arch: putative cytidylate kinase 6 175 5.3E-62 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A3L01_00675 36682663988a87a720f698389ab266d0 1920 SMART SM00710 27 49 74.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L01_00675 36682663988a87a720f698389ab266d0 1920 SMART SM00710 5 26 7500.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L01_00675 36682663988a87a720f698389ab266d0 1920 SMART SM00710 51 73 21.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L01_00675 36682663988a87a720f698389ab266d0 1920 SMART SM00710 74 94 1500.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L01_00675 36682663988a87a720f698389ab266d0 1920 SMART SM00710 117 138 710.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L01_00675 36682663988a87a720f698389ab266d0 1920 SMART SM00710 95 116 48.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L01_00675 36682663988a87a720f698389ab266d0 1920 Gene3D G3DSA:2.60.40.10 1781 1870 1.1E-25 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_00675 36682663988a87a720f698389ab266d0 1920 SMART SM00089 1788 1870 6.4E-30 T 23-10-2018 IPR022409 PKD/Chitinase domain A3L01_00675 36682663988a87a720f698389ab266d0 1920 SUPERFAMILY SSF52129 1139 1429 3.45E-6 T 23-10-2018 IPR029030 Caspase-like domain superfamily A3L01_00675 36682663988a87a720f698389ab266d0 1920 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 44 88 1.2E-8 T 23-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L01_00675 36682663988a87a720f698389ab266d0 1920 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 21 63 4.5E-7 T 23-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L01_00675 36682663988a87a720f698389ab266d0 1920 SMART SM00060 1785 1877 70.0 T 23-10-2018 IPR003961 Fibronectin type III GO:0005515 A3L01_00675 36682663988a87a720f698389ab266d0 1920 SMART SM00060 305 383 0.014 T 23-10-2018 IPR003961 Fibronectin type III GO:0005515 A3L01_00675 36682663988a87a720f698389ab266d0 1920 SUPERFAMILY SSF69318 837 1070 1.44E-9 T 23-10-2018 A3L01_00675 36682663988a87a720f698389ab266d0 1920 Pfam PF00801 PKD domain 1794 1858 4.2E-16 T 23-10-2018 IPR000601 PKD domain A3L01_00675 36682663988a87a720f698389ab266d0 1920 Gene3D G3DSA:2.60.40.10 198 304 3.7E-9 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_00675 36682663988a87a720f698389ab266d0 1920 SUPERFAMILY SSF51126 20 193 3.93E-19 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor A3L01_00675 36682663988a87a720f698389ab266d0 1920 Gene3D G3DSA:2.160.20.10 2 194 1.1E-17 T 23-10-2018 IPR012334 Pectin lyase fold A3L01_00675 36682663988a87a720f698389ab266d0 1920 Pfam PF05048 Periplasmic copper-binding protein (NosD) 10 199 3.1E-43 T 23-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L01_00675 36682663988a87a720f698389ab266d0 1920 SUPERFAMILY SSF49299 1786 1869 7.19E-25 T 23-10-2018 IPR035986 PKD domain superfamily A3L01_00675 36682663988a87a720f698389ab266d0 1920 Pfam PF01364 Peptidase family C25 1134 1429 4.0E-17 T 23-10-2018 IPR001769 Gingipain GO:0006508|GO:0008234 A3L01_00675 36682663988a87a720f698389ab266d0 1920 Gene3D G3DSA:3.40.50.1460 1298 1431 1.8E-5 T 23-10-2018 A3L01_00675 36682663988a87a720f698389ab266d0 1920 Pfam PF07705 CARDB 215 294 1.4E-7 T 23-10-2018 IPR011635 CARDB domain A3L01_03365 f6a0955d4137663f5ae901853523f43c 98 PIRSF PIRSF029904 1 98 2.8E-34 T 23-10-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD A3L01_03365 f6a0955d4137663f5ae901853523f43c 98 Gene3D G3DSA:1.10.287.1080 1 98 1.3E-28 T 23-10-2018 A3L01_03365 f6a0955d4137663f5ae901853523f43c 98 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 23 95 2.6E-17 T 23-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A3L01_03365 f6a0955d4137663f5ae901853523f43c 98 SUPERFAMILY SSF101386 1 95 8.87E-25 T 23-10-2018 A3L01_08865 7cc4f3c77d94fc09282b2c2aba9b0d3e 229 Gene3D G3DSA:3.20.20.70 2 228 1.0E-107 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_08865 7cc4f3c77d94fc09282b2c2aba9b0d3e 229 Pfam PF01791 DeoC/LacD family aldolase 11 220 3.1E-23 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L01_08865 7cc4f3c77d94fc09282b2c2aba9b0d3e 229 SMART SM01133 8 223 5.2E-117 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L01_08865 7cc4f3c77d94fc09282b2c2aba9b0d3e 229 SUPERFAMILY SSF51569 5 224 4.19E-94 T 23-10-2018 A3L01_08865 7cc4f3c77d94fc09282b2c2aba9b0d3e 229 PIRSF PIRSF001357 3 229 7.6E-93 T 23-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L01_08865 7cc4f3c77d94fc09282b2c2aba9b0d3e 229 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 9 221 7.7E-91 T 23-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L01_08865 7cc4f3c77d94fc09282b2c2aba9b0d3e 229 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 7 225 39.56 T 23-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 A3L01_03905 61bb7f50d9a7ea44f4019a4199627c64 415 SUPERFAMILY SSF103473 10 402 1.01E-37 T 23-10-2018 IPR036259 MFS transporter superfamily A3L01_03905 61bb7f50d9a7ea44f4019a4199627c64 415 Pfam PF05977 Transmembrane secretion effector 18 395 1.6E-27 T 23-10-2018 IPR010290 Transmembrane secretion effector A3L01_03905 61bb7f50d9a7ea44f4019a4199627c64 415 Gene3D G3DSA:1.20.1250.20 6 396 6.1E-35 T 23-10-2018 A3L01_02860 5de23d5c96bebccf996a7af0ab1175e7 192 SUPERFAMILY SSF56300 22 158 4.02E-21 T 23-10-2018 A3L01_02860 5de23d5c96bebccf996a7af0ab1175e7 192 Gene3D G3DSA:3.60.21.10 14 133 1.2E-9 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L01_02860 5de23d5c96bebccf996a7af0ab1175e7 192 Pfam PF00149 Calcineurin-like phosphoesterase 23 146 8.4E-8 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L01_02405 4e3f3c7486b97821a8ed360601ca60e8 438 Pfam PF01336 OB-fold nucleic acid binding domain 19 98 7.5E-12 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L01_02405 4e3f3c7486b97821a8ed360601ca60e8 438 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 2 438 43.751 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L01_02405 4e3f3c7486b97821a8ed360601ca60e8 438 SUPERFAMILY SSF50249 1 102 2.48E-27 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_02405 4e3f3c7486b97821a8ed360601ca60e8 438 SUPERFAMILY SSF55681 96 437 3.38E-99 T 23-10-2018 A3L01_02405 4e3f3c7486b97821a8ed360601ca60e8 438 Gene3D G3DSA:3.30.930.10 107 438 4.0E-122 T 23-10-2018 A3L01_02405 4e3f3c7486b97821a8ed360601ca60e8 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 393 407 2.7E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_02405 4e3f3c7486b97821a8ed360601ca60e8 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 204 217 2.7E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_02405 4e3f3c7486b97821a8ed360601ca60e8 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 353 369 2.7E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_02405 4e3f3c7486b97821a8ed360601ca60e8 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 187 199 2.7E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_02405 4e3f3c7486b97821a8ed360601ca60e8 438 Gene3D G3DSA:2.40.50.140 1 105 9.7E-28 T 23-10-2018 A3L01_02405 4e3f3c7486b97821a8ed360601ca60e8 438 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 5 438 5.2E-184 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L01_02405 4e3f3c7486b97821a8ed360601ca60e8 438 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 432 8.1E-97 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_01735 d625de7f4d85017849f273e30d3071d0 231 SUPERFAMILY SSF143555 13 180 9.16E-47 T 23-10-2018 A3L01_01735 d625de7f4d85017849f273e30d3071d0 231 Gene3D G3DSA:3.30.1330.130 5 173 8.2E-41 T 23-10-2018 A3L01_01735 d625de7f4d85017849f273e30d3071d0 231 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 23 165 1.7E-35 T 23-10-2018 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain A3L01_01735 d625de7f4d85017849f273e30d3071d0 231 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 181 216 4.1E-7 T 23-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 A3L01_01735 d625de7f4d85017849f273e30d3071d0 231 PIRSF PIRSF006578 3 217 2.3E-47 T 23-10-2018 IPR026328 Formylmethanofuran dehydrogenase, subunit E A3L01_03990 bb94cac7809b19f72c9bdbb743c90cb8 364 Pfam PF01988 VIT family 149 353 2.2E-45 T 23-10-2018 IPR008217 Ccc1 family A3L01_03990 bb94cac7809b19f72c9bdbb743c90cb8 364 Gene3D G3DSA:1.20.1260.10 11 144 9.7E-7 T 23-10-2018 IPR012347 Ferritin-like A3L01_03990 bb94cac7809b19f72c9bdbb743c90cb8 364 Pfam PF02915 Rubrerythrin 13 137 1.6E-5 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L01_03990 bb94cac7809b19f72c9bdbb743c90cb8 364 SUPERFAMILY SSF47240 5 141 9.2E-15 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L01_06565 6bb51a23c06160e5df4fa0b1197343fb 421 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 2 421 51.128 T 23-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 A3L01_06565 6bb51a23c06160e5df4fa0b1197343fb 421 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 188 348 1.2E-50 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L01_06565 6bb51a23c06160e5df4fa0b1197343fb 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 142 416 4.8E-28 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L01_06565 6bb51a23c06160e5df4fa0b1197343fb 421 PIRSF PIRSF001109 1 421 2.9E-197 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L01_06565 6bb51a23c06160e5df4fa0b1197343fb 421 Gene3D G3DSA:3.40.50.720 190 349 5.0E-177 T 23-10-2018 A3L01_06565 6bb51a23c06160e5df4fa0b1197343fb 421 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 7 421 3.7E-211 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L01_06565 6bb51a23c06160e5df4fa0b1197343fb 421 SMART SM00996 6 420 1.1E-142 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L01_06565 6bb51a23c06160e5df4fa0b1197343fb 421 SUPERFAMILY SSF51735 188 350 1.21E-68 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_06565 6bb51a23c06160e5df4fa0b1197343fb 421 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 210 226 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L01_06565 6bb51a23c06160e5df4fa0b1197343fb 421 Gene3D G3DSA:3.40.50.1480 9 410 5.0E-177 T 23-10-2018 A3L01_06565 6bb51a23c06160e5df4fa0b1197343fb 421 SUPERFAMILY SSF52283 5 421 3.06E-102 T 23-10-2018 A3L01_06565 6bb51a23c06160e5df4fa0b1197343fb 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 6 138 7.9E-35 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L01_06565 6bb51a23c06160e5df4fa0b1197343fb 421 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 78 92 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L01_06565 6bb51a23c06160e5df4fa0b1197343fb 421 SMART SM00997 188 349 1.4E-111 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L01_00945 5643ec6d54329d6e9f2001d11e8d28ef 600 Gene3D G3DSA:3.40.50.11540 163 341 4.0E-83 T 23-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_00945 5643ec6d54329d6e9f2001d11e8d28ef 600 SMART SM00928 439 484 3.3E-23 T 23-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_00945 5643ec6d54329d6e9f2001d11e8d28ef 600 Gene3D G3DSA:3.10.20.600 342 436 2.4E-32 T 23-10-2018 A3L01_00945 5643ec6d54329d6e9f2001d11e8d28ef 600 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 159 329 1.8E-50 T 23-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_00945 5643ec6d54329d6e9f2001d11e8d28ef 600 Pfam PF10531 SLBB domain 353 401 1.0E-9 T 23-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_00945 5643ec6d54329d6e9f2001d11e8d28ef 600 SUPERFAMILY SSF52833 7 98 1.68E-19 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L01_00945 5643ec6d54329d6e9f2001d11e8d28ef 600 Gene3D G3DSA:3.30.70.20 543 592 4.6E-13 T 23-10-2018 A3L01_00945 5643ec6d54329d6e9f2001d11e8d28ef 600 SUPERFAMILY SSF142019 112 350 5.62E-97 T 23-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_00945 5643ec6d54329d6e9f2001d11e8d28ef 600 SUPERFAMILY SSF54862 540 597 7.22E-15 T 23-10-2018 A3L01_00945 5643ec6d54329d6e9f2001d11e8d28ef 600 Pfam PF00037 4Fe-4S binding domain 571 593 2.2E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_00945 5643ec6d54329d6e9f2001d11e8d28ef 600 Pfam PF00037 4Fe-4S binding domain 540 563 5.5E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_00945 5643ec6d54329d6e9f2001d11e8d28ef 600 SUPERFAMILY SSF142984 351 434 5.89E-25 T 23-10-2018 A3L01_00945 5643ec6d54329d6e9f2001d11e8d28ef 600 Gene3D G3DSA:1.20.1440.230 437 538 5.0E-34 T 23-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_00945 5643ec6d54329d6e9f2001d11e8d28ef 600 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 440 524 3.7E-32 T 23-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_00945 5643ec6d54329d6e9f2001d11e8d28ef 600 Gene3D G3DSA:3.40.30.10 5 97 1.2E-20 T 23-10-2018 A3L01_00945 5643ec6d54329d6e9f2001d11e8d28ef 600 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 547 558 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_00945 5643ec6d54329d6e9f2001d11e8d28ef 600 SUPERFAMILY SSF140490 435 533 1.57E-36 T 23-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_00670 0b3995d18468fd9ebcc2fb4bc18a637d 741 Gene3D G3DSA:2.40.50.140 128 202 2.4E-14 T 23-10-2018 A3L01_00670 0b3995d18468fd9ebcc2fb4bc18a637d 741 SUPERFAMILY SSF50249 225 296 6.48E-10 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_00670 0b3995d18468fd9ebcc2fb4bc18a637d 741 SMART SM00316 131 196 3.9E-16 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L01_00670 0b3995d18468fd9ebcc2fb4bc18a637d 741 SUPERFAMILY SSF64182 336 734 8.89E-42 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L01_00670 0b3995d18468fd9ebcc2fb4bc18a637d 741 Gene3D G3DSA:2.10.230.20 2 41 1.7E-5 T 23-10-2018 A3L01_00670 0b3995d18468fd9ebcc2fb4bc18a637d 741 Pfam PF01336 OB-fold nucleic acid binding domain 227 296 2.0E-9 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L01_00670 0b3995d18468fd9ebcc2fb4bc18a637d 741 SUPERFAMILY SSF50249 121 199 1.42E-12 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_00670 0b3995d18468fd9ebcc2fb4bc18a637d 741 Gene3D G3DSA:3.90.1640.30 333 531 6.9E-9 T 23-10-2018 A3L01_00670 0b3995d18468fd9ebcc2fb4bc18a637d 741 Gene3D G3DSA:2.40.50.140 218 304 7.1E-7 T 23-10-2018 A3L01_00670 0b3995d18468fd9ebcc2fb4bc18a637d 741 SUPERFAMILY SSF57938 5 32 6.67E-5 T 23-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily A3L01_00670 0b3995d18468fd9ebcc2fb4bc18a637d 741 Pfam PF00575 S1 RNA binding domain 131 193 2.8E-11 T 23-10-2018 IPR003029 S1 domain GO:0003676 A3L01_08950 786fe7fd137af9a8d6d38ae20a9316e3 755 Pfam PF03176 MMPL family 524 744 2.2E-22 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A3L01_08950 786fe7fd137af9a8d6d38ae20a9316e3 755 Pfam PF03176 MMPL family 46 404 1.3E-35 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A3L01_08950 786fe7fd137af9a8d6d38ae20a9316e3 755 TIGRFAM TIGR00921 2A067: efflux transporter, putative, hydrophobe/amphiphile efflux-3 (HAE3) family 12 744 2.5E-226 T 23-10-2018 IPR004767 Hydrophobe/amphiphile efflux-3 HAE3 A3L01_08950 786fe7fd137af9a8d6d38ae20a9316e3 755 SUPERFAMILY SSF82866 559 749 6.54E-36 T 23-10-2018 A3L01_08950 786fe7fd137af9a8d6d38ae20a9316e3 755 SUPERFAMILY SSF82866 147 364 6.41E-42 T 23-10-2018 A3L01_08950 786fe7fd137af9a8d6d38ae20a9316e3 755 Gene3D G3DSA:1.20.1640.10 584 751 4.2E-13 T 23-10-2018 A3L01_08950 786fe7fd137af9a8d6d38ae20a9316e3 755 Gene3D G3DSA:1.20.1640.10 193 373 6.4E-24 T 23-10-2018 A3L01_06475 97342eda55d08f4114a110174983ac9f 394 SUPERFAMILY SSF103473 23 386 6.28E-30 T 23-10-2018 IPR036259 MFS transporter superfamily A3L01_06475 97342eda55d08f4114a110174983ac9f 394 Pfam PF07690 Major Facilitator Superfamily 25 350 3.5E-9 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L01_06475 97342eda55d08f4114a110174983ac9f 394 Gene3D G3DSA:1.20.1250.20 18 382 1.0E-25 T 23-10-2018 A3L01_05395 59e251d4442231bd152b322e37de58a2 324 Pfam PF05763 Protein of unknown function (DUF835) 183 320 7.8E-26 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L01_05395 59e251d4442231bd152b322e37de58a2 324 Pfam PF02915 Rubrerythrin 25 159 9.0E-23 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L01_05395 59e251d4442231bd152b322e37de58a2 324 Gene3D G3DSA:1.20.1260.10 15 163 1.1E-34 T 23-10-2018 IPR012347 Ferritin-like A3L01_05395 59e251d4442231bd152b322e37de58a2 324 SUPERFAMILY SSF47240 22 163 8.98E-28 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L01_08980 dd5f05c11898bccb2ee9eeb8783efbe8 361 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 12 321 1.9E-55 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L01_08980 dd5f05c11898bccb2ee9eeb8783efbe8 361 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 13 325 3.1E-53 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L01_06770 18d4f661a0f92f9211fc691d10679f05 139 Gene3D G3DSA:2.60.120.630 1 139 4.0E-52 T 23-10-2018 IPR023131 Mth639-like domain superfamily A3L01_06770 18d4f661a0f92f9211fc691d10679f05 139 Pfam PF04027 Domain of unknown function (DUF371) 6 136 1.4E-49 T 23-10-2018 IPR007171 Protein of unknown function DUF371 A3L01_04320 1f44bad3c43ef6ab2bd7799505ccf758 222 TIGRFAM TIGR03724 arch_bud32: Kae1-associated kinase Bud32 4 215 9.6E-73 T 23-10-2018 IPR022495 Serine/threonine-protein kinase Bud32 GO:0004674 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 A3L01_04320 1f44bad3c43ef6ab2bd7799505ccf758 222 Pfam PF01163 RIO1 family 48 149 6.1E-17 T 23-10-2018 A3L01_04320 1f44bad3c43ef6ab2bd7799505ccf758 222 SMART SM00220 1 221 7.2E-4 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A3L01_04320 1f44bad3c43ef6ab2bd7799505ccf758 222 SUPERFAMILY SSF56112 3 159 4.45E-29 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A3L01_04320 1f44bad3c43ef6ab2bd7799505ccf758 222 Gene3D G3DSA:3.30.200.20 21 90 7.2E-26 T 23-10-2018 A3L01_04320 1f44bad3c43ef6ab2bd7799505ccf758 222 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 126 138 - T 23-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 A3L01_04320 1f44bad3c43ef6ab2bd7799505ccf758 222 Gene3D G3DSA:1.10.510.10 99 217 2.1E-33 T 23-10-2018 A3L01_10325 479bcf8d09558db280b2d897c13e4ab4 222 TIGRFAM TIGR00703 TIGR00703: TIGR00703 family protein 1 222 1.2E-95 T 23-10-2018 IPR005266 Uncharacterised protein family UPF0128 A3L01_10325 479bcf8d09558db280b2d897c13e4ab4 222 Pfam PF03673 Uncharacterised protein family (UPF0128) 1 222 6.1E-101 T 23-10-2018 IPR005266 Uncharacterised protein family UPF0128 A3L01_10325 479bcf8d09558db280b2d897c13e4ab4 222 Hamap MF_00264 UPF0128 protein . 1 222 130.565 T 23-10-2018 IPR005266 Uncharacterised protein family UPF0128 A3L01_10325 479bcf8d09558db280b2d897c13e4ab4 222 ProDom PD023377 UPF0128 PYRAB08320 PH1314 PF1488 MJ1463 AQ_756 1 222 7.0E-101 T 23-10-2018 IPR005266 Uncharacterised protein family UPF0128 A3L01_04910 a540b76c3800b87e2bc7bd00a42f1935 283 Gene3D G3DSA:3.40.50.300 1 233 7.7E-60 T 23-10-2018 A3L01_04910 a540b76c3800b87e2bc7bd00a42f1935 283 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_04910 a540b76c3800b87e2bc7bd00a42f1935 283 SMART SM00382 28 215 5.7E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_04910 a540b76c3800b87e2bc7bd00a42f1935 283 SUPERFAMILY SSF52540 2 217 8.71E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_04910 a540b76c3800b87e2bc7bd00a42f1935 283 Pfam PF00005 ABC transporter 20 157 7.2E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_01600 a32529edb0f938859f44f0442871aece 819 SUPERFAMILY SSF48239 554 779 6.91E-9 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L01_01600 a32529edb0f938859f44f0442871aece 819 Gene3D G3DSA:3.40.50.12610 376 492 2.1E-6 T 23-10-2018 A3L01_01600 a32529edb0f938859f44f0442871aece 819 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 67 218 1.0E-14 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A3L01_08040 263eeed8172ba98c8e8d0f9a85bbec9c 428 Gene3D G3DSA:3.30.2290.10 1 206 3.3E-20 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L01_08040 263eeed8172ba98c8e8d0f9a85bbec9c 428 SUPERFAMILY SSF111283 2 422 6.41E-84 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L01_08040 263eeed8172ba98c8e8d0f9a85bbec9c 428 Pfam PF01523 Putative modulator of DNA gyrase 14 303 2.7E-48 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L01_03600 180a8d6a972815ae8bc00286a67bb206 277 Gene3D G3DSA:1.10.10.10 191 271 4.2E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_03600 180a8d6a972815ae8bc00286a67bb206 277 SUPERFAMILY SSF46785 205 269 3.13E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_03600 180a8d6a972815ae8bc00286a67bb206 277 Pfam PF13412 Winged helix-turn-helix DNA-binding 221 263 5.0E-8 T 23-10-2018 A3L01_07670 72141eb3693c540ce7e76b0f50db14ad 394 Pfam PF07690 Major Facilitator Superfamily 12 327 1.1E-38 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L01_07670 72141eb3693c540ce7e76b0f50db14ad 394 PRINTS PR01035 Tetracycline resistance protein signature 298 318 2.6E-7 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A3L01_07670 72141eb3693c540ce7e76b0f50db14ad 394 PRINTS PR01035 Tetracycline resistance protein signature 134 156 2.6E-7 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A3L01_07670 72141eb3693c540ce7e76b0f50db14ad 394 PRINTS PR01035 Tetracycline resistance protein signature 333 356 2.6E-7 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A3L01_07670 72141eb3693c540ce7e76b0f50db14ad 394 PRINTS PR01035 Tetracycline resistance protein signature 16 32 2.6E-7 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A3L01_07670 72141eb3693c540ce7e76b0f50db14ad 394 Gene3D G3DSA:1.20.1250.20 2 380 4.2E-52 T 23-10-2018 A3L01_07670 72141eb3693c540ce7e76b0f50db14ad 394 SUPERFAMILY SSF103473 5 381 3.92E-57 T 23-10-2018 IPR036259 MFS transporter superfamily A3L01_03435 05f07a4c6fc04d8ccc1d12b03f951a95 381 Pfam PF13360 PQQ-like domain 140 262 3.5E-6 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A3L01_03435 05f07a4c6fc04d8ccc1d12b03f951a95 381 SUPERFAMILY SSF50998 52 318 1.1E-20 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A3L01_03435 05f07a4c6fc04d8ccc1d12b03f951a95 381 Gene3D G3DSA:2.130.10.10 13 291 7.9E-22 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A3L01_09495 760228b1e51ec45778551c562da5162f 782 SUPERFAMILY SSF51445 2 416 2.26E-59 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L01_09495 760228b1e51ec45778551c562da5162f 782 PRINTS PR00742 Glycosyl hydrolase family 35 signature 93 112 1.0E-7 T 23-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A3L01_09495 760228b1e51ec45778551c562da5162f 782 PRINTS PR00742 Glycosyl hydrolase family 35 signature 13 30 1.0E-7 T 23-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A3L01_09495 760228b1e51ec45778551c562da5162f 782 Gene3D G3DSA:3.40.50.880 448 654 4.8E-14 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_09495 760228b1e51ec45778551c562da5162f 782 Pfam PF02449 Beta-galactosidase 24 418 2.1E-73 T 23-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A3L01_09495 760228b1e51ec45778551c562da5162f 782 SUPERFAMILY SSF52317 471 628 1.68E-7 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_00935 49693322079b262185faa3f888a16ecb 334 SUPERFAMILY SSF46548 225 332 3.49E-12 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L01_00935 49693322079b262185faa3f888a16ecb 334 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 306 317 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_00935 49693322079b262185faa3f888a16ecb 334 Gene3D G3DSA:1.10.1060.10 284 332 2.0E-5 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L01_00935 49693322079b262185faa3f888a16ecb 334 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 229 240 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_00935 49693322079b262185faa3f888a16ecb 334 Pfam PF17179 4Fe-4S dicluster domain 229 320 3.3E-23 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_06885 faf28ebebcec34d2c99051d0e5420e87 210 SUPERFAMILY SSF51366 2 208 4.99E-59 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L01_06885 faf28ebebcec34d2c99051d0e5420e87 210 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 3 202 1.9E-37 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L01_06885 faf28ebebcec34d2c99051d0e5420e87 210 SMART SM00934 3 203 1.9E-59 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L01_06885 faf28ebebcec34d2c99051d0e5420e87 210 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 56 69 - T 23-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L01_06885 faf28ebebcec34d2c99051d0e5420e87 210 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 4 202 2.1E-48 T 23-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L01_06885 faf28ebebcec34d2c99051d0e5420e87 210 Gene3D G3DSA:3.20.20.70 1 209 1.0E-63 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_06885 faf28ebebcec34d2c99051d0e5420e87 210 Hamap MF_01200_A Orotidine 5'-phosphate decarboxylase [pyrF]. 4 209 37.067 T 23-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L01_01125 63fff9e12d1dd593a45e03901e4732ce 148 Pfam PF01280 Ribosomal protein L19e 2 143 7.7E-59 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01125 63fff9e12d1dd593a45e03901e4732ce 148 SUPERFAMILY SSF48140 1 141 1.31E-57 T 23-10-2018 IPR035970 Ribosomal protein L19/L19e superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01125 63fff9e12d1dd593a45e03901e4732ce 148 Gene3D G3DSA:1.10.1200.240 56 148 3.2E-30 T 23-10-2018 A3L01_01125 63fff9e12d1dd593a45e03901e4732ce 148 ProSitePatterns PS00526 Ribosomal protein L19e signature. 5 24 - T 23-10-2018 IPR023638 Ribosomal protein L19/L19e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01125 63fff9e12d1dd593a45e03901e4732ce 148 SMART SM01416 1 144 3.1E-88 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01125 63fff9e12d1dd593a45e03901e4732ce 148 Gene3D G3DSA:1.10.1650.10 1 54 2.6E-25 T 23-10-2018 IPR015972 Ribosomal protein L19/L19e, domain 1 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01125 63fff9e12d1dd593a45e03901e4732ce 148 Hamap MF_01475 50S ribosomal protein L19e [rpl19e]. 1 147 25.794 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_09300 06897827cbe9f9316b3fe72f5d3e0dc3 277 PRINTS PR00990 Ribokinase signature 201 212 1.4E-6 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L01_09300 06897827cbe9f9316b3fe72f5d3e0dc3 277 PRINTS PR00990 Ribokinase signature 162 177 1.4E-6 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L01_09300 06897827cbe9f9316b3fe72f5d3e0dc3 277 PRINTS PR00990 Ribokinase signature 23 42 1.4E-6 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L01_09300 06897827cbe9f9316b3fe72f5d3e0dc3 277 Pfam PF00294 pfkB family carbohydrate kinase 4 274 3.1E-39 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A3L01_09300 06897827cbe9f9316b3fe72f5d3e0dc3 277 Gene3D G3DSA:3.40.1190.20 2 276 5.7E-60 T 23-10-2018 IPR029056 Ribokinase-like A3L01_09300 06897827cbe9f9316b3fe72f5d3e0dc3 277 SUPERFAMILY SSF53613 2 274 4.05E-54 T 23-10-2018 IPR029056 Ribokinase-like A3L01_09300 06897827cbe9f9316b3fe72f5d3e0dc3 277 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 232 245 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 Gene3D G3DSA:2.60.40.10 769 853 6.1E-5 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 SUPERFAMILY SSF51126 2549 2768 2.27E-9 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 TIGRFAM TIGR04213 PGF_pre_PGF: PGF-pre-PGF domain 3920 4001 8.3E-12 T 23-10-2018 IPR026453 PGF-pre-PGF domain A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 SUPERFAMILY SSF51126 2071 2208 8.52E-6 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 SUPERFAMILY SSF48726 951 1041 1.93E-5 T 23-10-2018 IPR036179 Immunoglobulin-like domain superfamily A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 Pfam PF13229 Right handed beta helix region 2614 2755 6.8E-8 T 23-10-2018 IPR039448 Right handed beta helix domain A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 Pfam PF13229 Right handed beta helix region 482 626 6.5E-8 T 23-10-2018 IPR039448 Right handed beta helix domain A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 SUPERFAMILY SSF51126 395 653 1.33E-27 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 Gene3D G3DSA:2.160.20.10 398 679 3.9E-16 T 23-10-2018 IPR012334 Pectin lyase fold A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 SMART SM00710 2614 2635 2700.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 SMART SM00710 2102 2124 8200.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 SMART SM00710 2565 2588 1400.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 SMART SM00710 2704 2725 250.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 SMART SM00710 2319 2340 5500.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 SMART SM00710 2656 2677 1200.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 SMART SM00710 2589 2610 2700.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 SMART SM00710 507 534 3000.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 SMART SM00710 2077 2098 230.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 SMART SM00710 483 506 1500.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 SMART SM00710 561 585 5800.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 SMART SM00710 1955 1976 2200.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 SMART SM00710 2908 2928 2900.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 SMART SM00710 2680 2701 5100.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 SMART SM00710 535 559 600.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L01_05410 070efd48d44bfbdeee8c742ae2ce1792 4058 Gene3D G3DSA:2.60.120.260 2370 2537 2.3E-7 T 23-10-2018 IPR008979 Galactose-binding-like domain superfamily A3L01_01920 9fddb43a2828b66b1f58e8b1fbff2081 373 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 6 322 9.1E-47 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A3L01_01920 9fddb43a2828b66b1f58e8b1fbff2081 373 Gene3D G3DSA:3.40.720.10 1 371 1.3E-54 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L01_01920 9fddb43a2828b66b1f58e8b1fbff2081 373 SUPERFAMILY SSF53649 1 359 3.05E-75 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L01_02060 4f797289d74f7a521adb4069c8de4a18 245 Gene3D G3DSA:3.20.20.190 2 234 6.0E-41 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A3L01_02060 4f797289d74f7a521adb4069c8de4a18 245 SUPERFAMILY SSF51695 3 227 1.23E-36 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A3L01_02060 4f797289d74f7a521adb4069c8de4a18 245 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 9 222 1.7E-16 T 23-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A3L01_09870 eb7c09e63d9609d2866f74489e35cd5d 393 SUPERFAMILY SSF161098 187 380 1.3E-17 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_09870 eb7c09e63d9609d2866f74489e35cd5d 393 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 209 386 6.3E-12 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_09870 eb7c09e63d9609d2866f74489e35cd5d 393 Gene3D G3DSA:1.10.3720.10 182 389 9.9E-17 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_02210 d631bb8d291df3f80d73083326639959 149 Pfam PF08905 Domain of unknown function (DUF1850) 42 121 1.1E-8 T 23-10-2018 IPR015001 Protein of unknown function DUF1850 A3L01_07685 9089c68e583b1ed469e07ef3fee7da82 388 Gene3D G3DSA:1.20.1250.20 11 198 8.0E-15 T 23-10-2018 A3L01_07685 9089c68e583b1ed469e07ef3fee7da82 388 Gene3D G3DSA:1.20.1250.20 209 388 2.9E-15 T 23-10-2018 A3L01_07685 9089c68e583b1ed469e07ef3fee7da82 388 Pfam PF07690 Major Facilitator Superfamily 23 345 3.8E-17 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L01_07685 9089c68e583b1ed469e07ef3fee7da82 388 SUPERFAMILY SSF103473 11 385 5.23E-41 T 23-10-2018 IPR036259 MFS transporter superfamily A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Pfam PF00801 PKD domain 3498 3561 6.4E-12 T 23-10-2018 IPR000601 PKD domain A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Pfam PF00801 PKD domain 3963 4020 1.2E-12 T 23-10-2018 IPR000601 PKD domain A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 SUPERFAMILY SSF49452 2547 2631 5.3E-7 T 23-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 SUPERFAMILY SSF49299 3487 3570 3.53E-13 T 23-10-2018 IPR035986 PKD domain superfamily A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Pfam PF07705 CARDB 637 735 7.7E-10 T 23-10-2018 IPR011635 CARDB domain A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Pfam PF07705 CARDB 534 629 5.9E-13 T 23-10-2018 IPR011635 CARDB domain A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Pfam PF07705 CARDB 1607 1706 1.1E-14 T 23-10-2018 IPR011635 CARDB domain A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Pfam PF07705 CARDB 1502 1599 2.7E-16 T 23-10-2018 IPR011635 CARDB domain A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Pfam PF07705 CARDB 1071 1178 4.0E-10 T 23-10-2018 IPR011635 CARDB domain A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Pfam PF07705 CARDB 422 524 3.1E-5 T 23-10-2018 IPR011635 CARDB domain A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Pfam PF07705 CARDB 1186 1282 1.4E-10 T 23-10-2018 IPR011635 CARDB domain A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Pfam PF07705 CARDB 1291 1388 1.8E-13 T 23-10-2018 IPR011635 CARDB domain A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Pfam PF07705 CARDB 847 952 3.1E-5 T 23-10-2018 IPR011635 CARDB domain A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Pfam PF07705 CARDB 960 1062 7.8E-6 T 23-10-2018 IPR011635 CARDB domain A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Pfam PF07705 CARDB 1397 1494 4.5E-12 T 23-10-2018 IPR011635 CARDB domain A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Gene3D G3DSA:2.60.40.10 3870 3950 1.5E-6 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 SUPERFAMILY SSF49299 3950 4029 1.29E-18 T 23-10-2018 IPR035986 PKD domain superfamily A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Gene3D G3DSA:2.60.40.10 3482 3570 1.1E-18 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Gene3D G3DSA:2.60.40.10 3951 4030 4.8E-22 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 SMART SM00089 3954 4031 2.7E-22 T 23-10-2018 IPR022409 PKD/Chitinase domain A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 SMART SM00089 3491 3572 9.6E-20 T 23-10-2018 IPR022409 PKD/Chitinase domain A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Gene3D G3DSA:2.60.40.10 1498 1603 2.7E-21 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Gene3D G3DSA:2.60.40.10 529 633 8.0E-21 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Gene3D G3DSA:2.60.40.10 956 1067 3.1E-10 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Gene3D G3DSA:2.60.40.10 834 955 1.6E-8 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Gene3D G3DSA:2.60.40.10 634 741 1.5E-13 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Gene3D G3DSA:2.60.40.10 1604 1715 6.4E-18 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Gene3D G3DSA:2.60.40.10 408 528 2.8E-10 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Gene3D G3DSA:2.60.40.10 1392 1497 2.9E-16 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Gene3D G3DSA:2.60.40.10 1287 1391 1.2E-16 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Gene3D G3DSA:2.60.40.10 1184 1286 6.5E-17 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Gene3D G3DSA:2.60.40.10 1724 1815 4.0E-5 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Gene3D G3DSA:2.60.40.10 1070 1183 2.1E-15 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_05375 9ada5af34651707b75ff653cbb502821 4489 Gene3D G3DSA:2.60.40.10 1892 1968 2.4E-7 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_02780 f965598f9eb4acb8fa38d8d1e4948bc3 407 Pfam PF13439 Glycosyltransferase Family 4 17 185 9.9E-27 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L01_02780 f965598f9eb4acb8fa38d8d1e4948bc3 407 Gene3D G3DSA:3.40.50.2000 8 373 1.6E-74 T 23-10-2018 A3L01_02780 f965598f9eb4acb8fa38d8d1e4948bc3 407 SUPERFAMILY SSF53756 5 386 5.83E-75 T 23-10-2018 A3L01_02780 f965598f9eb4acb8fa38d8d1e4948bc3 407 Pfam PF00534 Glycosyl transferases group 1 199 365 7.6E-24 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L01_02780 f965598f9eb4acb8fa38d8d1e4948bc3 407 Gene3D G3DSA:3.40.50.2000 183 372 1.6E-74 T 23-10-2018 A3L01_01120 19b0214ee25cdf0bab104fb88f019c4c 127 ProSitePatterns PS00580 Ribosomal protein L32e signature. 21 43 - T 23-10-2018 IPR018263 Ribosomal protein L32e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01120 19b0214ee25cdf0bab104fb88f019c4c 127 SMART SM01393 18 125 7.7E-61 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01120 19b0214ee25cdf0bab104fb88f019c4c 127 Pfam PF01655 Ribosomal protein L32 18 125 7.8E-40 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01120 19b0214ee25cdf0bab104fb88f019c4c 127 Hamap MF_00810 50S ribosomal protein L32e [rpl32e]. 2 126 31.196 T 23-10-2018 IPR023654 Ribosomal protein L32e, archaeal GO:0003735|GO:0005840|GO:0006412 A3L01_01120 19b0214ee25cdf0bab104fb88f019c4c 127 ProDom PD003823 RIBOSOMAL L32 RIBONUCLEOPROTEIN 60S L32E 50S L32 STRAIN CHROMOSOME DIRECT 19 125 6.0E-54 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01120 19b0214ee25cdf0bab104fb88f019c4c 127 SUPERFAMILY SSF52042 5 126 8.5E-46 T 23-10-2018 IPR036351 Ribosomal protein L32e superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_04075 57d667999f6553a8508e89e2f7f00a5c 397 SUPERFAMILY SSF52540 1 315 2.14E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_04075 57d667999f6553a8508e89e2f7f00a5c 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 92 110 4.4E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_04075 57d667999f6553a8508e89e2f7f00a5c 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 3 23 4.4E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_04075 57d667999f6553a8508e89e2f7f00a5c 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 75 90 4.4E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_04075 57d667999f6553a8508e89e2f7f00a5c 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 24 42 4.4E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_04075 57d667999f6553a8508e89e2f7f00a5c 397 Gene3D G3DSA:1.10.8.470 126 215 5.1E-31 T 23-10-2018 A3L01_04075 57d667999f6553a8508e89e2f7f00a5c 397 Pfam PF02824 TGS domain 341 393 3.1E-14 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A3L01_04075 57d667999f6553a8508e89e2f7f00a5c 397 Pfam PF08438 GTPase of unknown function C-terminal 220 327 8.3E-35 T 23-10-2018 IPR013646 Uncharacterised GTP-binding protein, C-terminal A3L01_04075 57d667999f6553a8508e89e2f7f00a5c 397 Gene3D G3DSA:3.10.20.30 319 397 5.1E-31 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L01_04075 57d667999f6553a8508e89e2f7f00a5c 397 Pfam PF01926 50S ribosome-binding GTPase 2 130 7.9E-20 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_04075 57d667999f6553a8508e89e2f7f00a5c 397 SUPERFAMILY SSF81271 323 393 5.76E-19 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A3L01_06255 e07a2ad404e3fb4c32e0d3b6967c08a2 299 SUPERFAMILY SSF47954 206 298 2.45E-29 T 23-10-2018 IPR036915 Cyclin-like superfamily A3L01_06255 e07a2ad404e3fb4c32e0d3b6967c08a2 299 SMART SM00385 210 291 8.0E-14 T 23-10-2018 IPR013763 Cyclin-like A3L01_06255 e07a2ad404e3fb4c32e0d3b6967c08a2 299 SMART SM00385 114 195 1.8E-12 T 23-10-2018 IPR013763 Cyclin-like A3L01_06255 e07a2ad404e3fb4c32e0d3b6967c08a2 299 SUPERFAMILY SSF47954 113 200 6.81E-28 T 23-10-2018 IPR036915 Cyclin-like superfamily A3L01_06255 e07a2ad404e3fb4c32e0d3b6967c08a2 299 PRINTS PR00685 Transcription initiation factor IIB signature 19 39 2.8E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L01_06255 e07a2ad404e3fb4c32e0d3b6967c08a2 299 PRINTS PR00685 Transcription initiation factor IIB signature 211 229 2.8E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L01_06255 e07a2ad404e3fb4c32e0d3b6967c08a2 299 PRINTS PR00685 Transcription initiation factor IIB signature 182 197 2.8E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L01_06255 e07a2ad404e3fb4c32e0d3b6967c08a2 299 PRINTS PR00685 Transcription initiation factor IIB signature 54 75 2.8E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L01_06255 e07a2ad404e3fb4c32e0d3b6967c08a2 299 PRINTS PR00685 Transcription initiation factor IIB signature 277 291 2.8E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L01_06255 e07a2ad404e3fb4c32e0d3b6967c08a2 299 PRINTS PR00685 Transcription initiation factor IIB signature 41 54 2.8E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L01_06255 e07a2ad404e3fb4c32e0d3b6967c08a2 299 PRINTS PR00685 Transcription initiation factor IIB signature 156 175 2.8E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L01_06255 e07a2ad404e3fb4c32e0d3b6967c08a2 299 PRINTS PR00685 Transcription initiation factor IIB signature 245 261 2.8E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L01_06255 e07a2ad404e3fb4c32e0d3b6967c08a2 299 Gene3D G3DSA:1.10.472.170 6 197 4.0E-68 T 23-10-2018 A3L01_06255 e07a2ad404e3fb4c32e0d3b6967c08a2 299 Pfam PF00382 Transcription factor TFIIB repeat 117 186 1.3E-20 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A3L01_06255 e07a2ad404e3fb4c32e0d3b6967c08a2 299 Pfam PF00382 Transcription factor TFIIB repeat 212 282 8.9E-24 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A3L01_06255 e07a2ad404e3fb4c32e0d3b6967c08a2 299 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 148 163 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L01_06255 e07a2ad404e3fb4c32e0d3b6967c08a2 299 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 1 297 44.824 T 23-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea A3L01_06255 e07a2ad404e3fb4c32e0d3b6967c08a2 299 SUPERFAMILY SSF57783 4 50 2.1E-17 T 23-10-2018 A3L01_06255 e07a2ad404e3fb4c32e0d3b6967c08a2 299 Pfam PF08271 TFIIB zinc-binding 6 47 2.1E-19 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type A3L01_06255 e07a2ad404e3fb4c32e0d3b6967c08a2 299 Gene3D G3DSA:1.10.472.10 207 299 1.9E-28 T 23-10-2018 A3L01_02485 c10864f9d07a2fefb7816a37b28d5722 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 191 209 2.3E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_02485 c10864f9d07a2fefb7816a37b28d5722 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 218 233 2.3E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_02485 c10864f9d07a2fefb7816a37b28d5722 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 170 190 2.3E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_02485 c10864f9d07a2fefb7816a37b28d5722 359 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 169 326 1.9E-16 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L01_02485 c10864f9d07a2fefb7816a37b28d5722 359 Gene3D G3DSA:3.40.50.300 162 357 8.8E-58 T 23-10-2018 A3L01_02485 c10864f9d07a2fefb7816a37b28d5722 359 Pfam PF06858 Nucleolar GTP-binding protein 1 (NOG1) 234 291 4.3E-25 T 23-10-2018 IPR010674 Nucleolar GTP-binding protein 1, Rossman-fold domain GO:0005525 A3L01_02485 c10864f9d07a2fefb7816a37b28d5722 359 SUPERFAMILY SSF52540 168 351 5.64E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_02485 c10864f9d07a2fefb7816a37b28d5722 359 Gene3D G3DSA:1.20.120.1190 1 161 9.0E-56 T 23-10-2018 A3L01_05705 e898ef4af71eff30bc361b8de6529faf 354 SUPERFAMILY SSF52540 4 244 1.91E-89 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_05705 e898ef4af71eff30bc361b8de6529faf 354 Gene3D G3DSA:3.40.50.300 1 237 9.3E-79 T 23-10-2018 A3L01_05705 e898ef4af71eff30bc361b8de6529faf 354 Pfam PF08402 TOBE domain 276 349 1.8E-6 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A3L01_05705 e898ef4af71eff30bc361b8de6529faf 354 Gene3D G3DSA:2.40.50.140 289 339 3.3E-6 T 23-10-2018 A3L01_05705 e898ef4af71eff30bc361b8de6529faf 354 Pfam PF00005 ABC transporter 19 161 2.7E-34 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_05705 e898ef4af71eff30bc361b8de6529faf 354 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_05705 e898ef4af71eff30bc361b8de6529faf 354 SUPERFAMILY SSF50331 237 349 8.08E-13 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L01_05705 e898ef4af71eff30bc361b8de6529faf 354 Gene3D G3DSA:2.40.50.100 238 280 3.3E-6 T 23-10-2018 A3L01_05705 e898ef4af71eff30bc361b8de6529faf 354 SMART SM00382 28 211 5.6E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_05705 e898ef4af71eff30bc361b8de6529faf 354 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 34 326 3.6E-107 T 23-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 A3L01_03630 6d2c3e7398c26719b975a0f230280b9e 97 Gene3D G3DSA:1.10.287.370 1 97 1.1E-34 T 23-10-2018 IPR009053 Prefoldin A3L01_03630 6d2c3e7398c26719b975a0f230280b9e 97 Pfam PF01920 Prefoldin subunit 12 96 5.0E-8 T 23-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 A3L01_03630 6d2c3e7398c26719b975a0f230280b9e 97 SUPERFAMILY SSF46579 6 96 9.29E-7 T 23-10-2018 A3L01_05850 9506985f4354c0ab32ddde957ee97fc1 125 Pfam PF01850 PIN domain 5 119 5.9E-13 T 23-10-2018 IPR002716 PIN domain A3L01_05850 9506985f4354c0ab32ddde957ee97fc1 125 SUPERFAMILY SSF88723 1 118 9.25E-17 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L01_05850 9506985f4354c0ab32ddde957ee97fc1 125 Gene3D G3DSA:3.40.50.1010 4 122 2.0E-16 T 23-10-2018 A3L01_02005 80811f49d33fc6f0097d9438d710d22e 225 Gene3D G3DSA:3.40.50.1000 3 135 3.5E-12 T 23-10-2018 IPR023214 HAD superfamily A3L01_02005 80811f49d33fc6f0097d9438d710d22e 225 Gene3D G3DSA:1.10.150.520 14 85 3.5E-12 T 23-10-2018 A3L01_02005 80811f49d33fc6f0097d9438d710d22e 225 SUPERFAMILY SSF56784 1 185 2.89E-19 T 23-10-2018 IPR036412 HAD-like superfamily A3L01_02005 80811f49d33fc6f0097d9438d710d22e 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 135 1.5E-13 T 23-10-2018 A3L01_07525 9de1bc6db42a2202afc6cfbb7b67e4c8 351 Gene3D G3DSA:1.10.10.10 1 83 2.1E-31 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_07525 9de1bc6db42a2202afc6cfbb7b67e4c8 351 Gene3D G3DSA:3.40.50.150 101 326 2.8E-87 T 23-10-2018 A3L01_07525 9de1bc6db42a2202afc6cfbb7b67e4c8 351 Pfam PF01861 Protein of unknown function DUF43 106 350 1.0E-121 T 23-10-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal A3L01_07525 9de1bc6db42a2202afc6cfbb7b67e4c8 351 SUPERFAMILY SSF53335 165 285 1.15E-9 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_07525 9de1bc6db42a2202afc6cfbb7b67e4c8 351 PIRSF PIRSF005895 1 351 4.9E-160 T 23-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 A3L01_07525 9de1bc6db42a2202afc6cfbb7b67e4c8 351 Hamap MF_01947 N(4)-bis(aminopropyl)spermidine synthase [bpsA]. 15 351 50.906 T 23-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 A3L01_09730 701cf1cf11c69b264cc4bc4850304a57 250 Gene3D G3DSA:3.40.1390.30 6 238 3.8E-76 T 23-10-2018 A3L01_09730 701cf1cf11c69b264cc4bc4850304a57 250 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 248 6.0E-60 T 23-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A3L01_09730 701cf1cf11c69b264cc4bc4850304a57 250 SUPERFAMILY SSF102705 1 245 2.62E-70 T 23-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily A3L01_09730 701cf1cf11c69b264cc4bc4850304a57 250 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 5 238 9.5E-59 T 23-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A3L01_09730 701cf1cf11c69b264cc4bc4850304a57 250 Gene3D G3DSA:3.40.1390.30 96 221 3.8E-76 T 23-10-2018 A3L01_00520 15182a7ff4e3af476537a467c9201394 202 Gene3D G3DSA:1.10.10.10 2 82 6.7E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_00520 15182a7ff4e3af476537a467c9201394 202 Gene3D G3DSA:1.10.10.10 83 161 1.9E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_00520 15182a7ff4e3af476537a467c9201394 202 SUPERFAMILY SSF46785 3 81 2.3E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_00520 15182a7ff4e3af476537a467c9201394 202 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 175 5.5E-31 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A3L01_00520 15182a7ff4e3af476537a467c9201394 202 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 153 8.1E-36 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A3L01_00520 15182a7ff4e3af476537a467c9201394 202 SUPERFAMILY SSF46785 85 152 3.39E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_00520 15182a7ff4e3af476537a467c9201394 202 PIRSF PIRSF019345 2 194 5.2E-46 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A3L01_00155 52ed5686efa21974ac370354e1e6f3df 1116 Pfam PF10102 Domain of unknown function (DUF2341) 564 642 2.1E-9 T 23-10-2018 IPR018765 Domain of unknown function DUF2341 A3L01_06020 024ab882b2d186f6b6c4b0f3e77eecc7 282 Gene3D G3DSA:3.30.479.30 52 183 1.1E-51 T 23-10-2018 A3L01_06020 024ab882b2d186f6b6c4b0f3e77eecc7 282 SMART SM00244 24 181 1.1E-71 T 23-10-2018 IPR001107 Band 7 domain A3L01_06020 024ab882b2d186f6b6c4b0f3e77eecc7 282 Pfam PF01145 SPFH domain / Band 7 family 28 198 2.8E-38 T 23-10-2018 IPR001107 Band 7 domain A3L01_06020 024ab882b2d186f6b6c4b0f3e77eecc7 282 PRINTS PR00721 Stomatin signature 78 99 6.5E-74 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L01_06020 024ab882b2d186f6b6c4b0f3e77eecc7 282 PRINTS PR00721 Stomatin signature 157 175 6.5E-74 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L01_06020 024ab882b2d186f6b6c4b0f3e77eecc7 282 PRINTS PR00721 Stomatin signature 113 130 6.5E-74 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L01_06020 024ab882b2d186f6b6c4b0f3e77eecc7 282 PRINTS PR00721 Stomatin signature 176 197 6.5E-74 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L01_06020 024ab882b2d186f6b6c4b0f3e77eecc7 282 PRINTS PR00721 Stomatin signature 201 224 6.5E-74 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L01_06020 024ab882b2d186f6b6c4b0f3e77eecc7 282 PRINTS PR00721 Stomatin signature 133 156 6.5E-74 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L01_06020 024ab882b2d186f6b6c4b0f3e77eecc7 282 PRINTS PR00721 Stomatin signature 31 53 6.5E-74 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L01_06020 024ab882b2d186f6b6c4b0f3e77eecc7 282 SUPERFAMILY SSF117892 55 188 4.45E-47 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily A3L01_07020 5634f00721f380fb2ee65719ff0aa78d 392 Gene3D G3DSA:1.10.3720.10 132 370 3.5E-28 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_07020 5634f00721f380fb2ee65719ff0aa78d 392 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 160 375 1.6E-32 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_07020 5634f00721f380fb2ee65719ff0aa78d 392 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 44 98 1.7E-5 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A3L01_07020 5634f00721f380fb2ee65719ff0aa78d 392 SUPERFAMILY SSF161098 137 356 2.75E-30 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_01815 8f6c43a8da13ee575949fb1e75636f5d 456 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 256 1.7E-29 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_01815 8f6c43a8da13ee575949fb1e75636f5d 456 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 443 1.2E-177 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_01815 8f6c43a8da13ee575949fb1e75636f5d 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 7.0E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_01815 8f6c43a8da13ee575949fb1e75636f5d 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 208 221 7.0E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_01815 8f6c43a8da13ee575949fb1e75636f5d 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 7.0E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_01815 8f6c43a8da13ee575949fb1e75636f5d 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 7.0E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_01815 8f6c43a8da13ee575949fb1e75636f5d 456 SUPERFAMILY SSF53738 155 259 2.79E-30 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_01815 8f6c43a8da13ee575949fb1e75636f5d 456 Gene3D G3DSA:3.40.120.10 257 365 2.9E-75 T 23-10-2018 A3L01_01815 8f6c43a8da13ee575949fb1e75636f5d 456 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 380 441 3.4E-13 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_01815 8f6c43a8da13ee575949fb1e75636f5d 456 Gene3D G3DSA:3.40.120.10 1 152 1.8E-62 T 23-10-2018 A3L01_01815 8f6c43a8da13ee575949fb1e75636f5d 456 Gene3D G3DSA:3.40.120.10 169 358 2.9E-75 T 23-10-2018 A3L01_01815 8f6c43a8da13ee575949fb1e75636f5d 456 SUPERFAMILY SSF55957 358 455 4.32E-23 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_01815 8f6c43a8da13ee575949fb1e75636f5d 456 SUPERFAMILY SSF53738 3 180 1.96E-47 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_01815 8f6c43a8da13ee575949fb1e75636f5d 456 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 137 4.9E-47 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_01815 8f6c43a8da13ee575949fb1e75636f5d 456 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 261 370 1.5E-26 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_01815 8f6c43a8da13ee575949fb1e75636f5d 456 Gene3D G3DSA:3.30.310.50 371 455 2.1E-30 T 23-10-2018 A3L01_01815 8f6c43a8da13ee575949fb1e75636f5d 456 SUPERFAMILY SSF53738 261 367 1.22E-25 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_07715 75e81297fdf94b06967d3c10df94c647 159 Pfam PF03031 NLI interacting factor-like phosphatase 2 155 1.3E-8 T 23-10-2018 IPR004274 FCP1 homology domain A3L01_07715 75e81297fdf94b06967d3c10df94c647 159 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 2 131 6.1E-14 T 23-10-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC A3L01_07715 75e81297fdf94b06967d3c10df94c647 159 TIGRFAM TIGR01685 MDP-1: magnesium-dependent phosphatase-1 2 152 3.2E-26 T 23-10-2018 IPR010036 Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type GO:0016791 A3L01_07715 75e81297fdf94b06967d3c10df94c647 159 SUPERFAMILY SSF56784 2 144 1.73E-16 T 23-10-2018 IPR036412 HAD-like superfamily A3L01_07715 75e81297fdf94b06967d3c10df94c647 159 Gene3D G3DSA:3.40.50.1000 1 158 2.1E-25 T 23-10-2018 IPR023214 HAD superfamily A3L01_05500 b046563b86dd44911a4317ad37dd5327 630 Pfam PF12838 4Fe-4S dicluster domain 575 617 3.8E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_05500 b046563b86dd44911a4317ad37dd5327 630 Pfam PF01472 PUA domain 134 204 2.3E-16 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L01_05500 b046563b86dd44911a4317ad37dd5327 630 SMART SM00359 133 207 1.1E-18 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L01_05500 b046563b86dd44911a4317ad37dd5327 630 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 575 586 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_05500 b046563b86dd44911a4317ad37dd5327 630 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 95 203 1.9E-11 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L01_05500 b046563b86dd44911a4317ad37dd5327 630 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 252 430 6.4E-45 T 23-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 A3L01_05500 b046563b86dd44911a4317ad37dd5327 630 SUPERFAMILY SSF52402 223 418 7.72E-45 T 23-10-2018 A3L01_05500 b046563b86dd44911a4317ad37dd5327 630 Gene3D G3DSA:3.40.50.620 214 465 1.3E-49 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_05500 b046563b86dd44911a4317ad37dd5327 630 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 606 617 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_05500 b046563b86dd44911a4317ad37dd5327 630 SUPERFAMILY SSF54862 562 622 2.37E-14 T 23-10-2018 A3L01_05500 b046563b86dd44911a4317ad37dd5327 630 SUPERFAMILY SSF88697 132 204 1.05E-15 T 23-10-2018 IPR015947 PUA-like superfamily A3L01_05500 b046563b86dd44911a4317ad37dd5327 630 Gene3D G3DSA:3.30.70.20 571 621 3.8E-11 T 23-10-2018 A3L01_05500 b046563b86dd44911a4317ad37dd5327 630 Gene3D G3DSA:2.30.130.10 130 207 2.9E-15 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L01_01275 2c431fc333875ea9dd7599d7b180b636 108 Pfam PF03551 Transcriptional regulator PadR-like family 21 93 1.6E-18 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L01_01275 2c431fc333875ea9dd7599d7b180b636 108 Gene3D G3DSA:1.10.10.10 2 108 1.5E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_01275 2c431fc333875ea9dd7599d7b180b636 108 SUPERFAMILY SSF46785 3 106 1.69E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_08795 7bd57342b70508026d6538e93a97af55 412 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 376 9.6E-59 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_08795 7bd57342b70508026d6538e93a97af55 412 Gene3D G3DSA:1.10.645.20 7 376 6.6E-117 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_08795 7bd57342b70508026d6538e93a97af55 412 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 44 69 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 A3L01_08795 7bd57342b70508026d6538e93a97af55 412 SUPERFAMILY SSF56762 15 376 1.7E-101 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_08795 7bd57342b70508026d6538e93a97af55 412 Pfam PF00374 Nickel-dependent hydrogenase 44 112 9.8E-14 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L01_04065 40bc2bc8214812723411bcd1807c50eb 160 Gene3D G3DSA:3.30.70.920 57 160 5.7E-32 T 23-10-2018 A3L01_04065 40bc2bc8214812723411bcd1807c50eb 160 SMART SM00344 4 105 8.0E-10 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L01_04065 40bc2bc8214812723411bcd1807c50eb 160 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 4.8E-14 T 23-10-2018 A3L01_04065 40bc2bc8214812723411bcd1807c50eb 160 SUPERFAMILY SSF46785 3 58 3.67E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_04065 40bc2bc8214812723411bcd1807c50eb 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 1.4E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_04065 40bc2bc8214812723411bcd1807c50eb 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 1.4E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_04065 40bc2bc8214812723411bcd1807c50eb 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 1.4E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_04065 40bc2bc8214812723411bcd1807c50eb 160 Gene3D G3DSA:1.10.10.10 1 56 4.1E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_04955 0d43dc2293234632f959a2f4bac21e4a 174 Gene3D G3DSA:1.20.1260.10 1 168 2.1E-52 T 23-10-2018 IPR012347 Ferritin-like A3L01_04955 0d43dc2293234632f959a2f4bac21e4a 174 SUPERFAMILY SSF47240 1 161 3.13E-59 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L01_04955 0d43dc2293234632f959a2f4bac21e4a 174 Pfam PF00210 Ferritin-like domain 7 142 2.9E-44 T 23-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A3L01_08135 465a540041f2b8e03f843e8d22e0b3d8 178 Pfam PF09153 Domain of unknown function (DUF1938) 1 85 1.9E-22 T 23-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 A3L01_08135 465a540041f2b8e03f843e8d22e0b3d8 178 Gene3D G3DSA:1.10.10.10 89 174 5.9E-32 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_08135 465a540041f2b8e03f843e8d22e0b3d8 178 SUPERFAMILY SSF46767 90 169 2.35E-22 T 23-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 A3L01_08135 465a540041f2b8e03f843e8d22e0b3d8 178 Gene3D G3DSA:3.30.160.70 1 88 2.8E-15 T 23-10-2018 A3L01_08135 465a540041f2b8e03f843e8d22e0b3d8 178 SUPERFAMILY SSF53155 1 88 9.42E-21 T 23-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A3L01_08135 465a540041f2b8e03f843e8d22e0b3d8 178 ProDom PD068053 METHYLTRANSFERASE DNA METHYLATED-DNA--PROTEIN-CYSTEINE 6-O- O-6-METHYLGUANINE-DNA- REPAIR MGMT DAMAGE ALKYLTRANSFERASE METHYLGUANINE-DNA 1 96 2.0E-15 T 23-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 A3L01_08135 465a540041f2b8e03f843e8d22e0b3d8 178 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 91 169 2.8E-24 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A3L01_08135 465a540041f2b8e03f843e8d22e0b3d8 178 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 90 167 5.3E-26 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A3L01_08135 465a540041f2b8e03f843e8d22e0b3d8 178 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 139 145 - T 23-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A3L01_01785 c7035008b915dd3003f047d8e5a55315 189 Gene3D G3DSA:2.60.120.10 1 189 1.8E-74 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L01_01785 c7035008b915dd3003f047d8e5a55315 189 Pfam PF06560 Glucose-6-phosphate isomerase (GPI) 25 179 6.3E-41 T 23-10-2018 IPR010551 Glucose-6-phosphate isomerase, prokaryote GO:0004347|GO:0005737|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 A3L01_01785 c7035008b915dd3003f047d8e5a55315 189 PIRSF PIRSF019325 1 189 1.6E-73 T 23-10-2018 IPR016758 Glucose-6-phosphate isomerase, archaea/bacteria GO:0004347|GO:0005506 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 A3L01_01785 c7035008b915dd3003f047d8e5a55315 189 SUPERFAMILY SSF51182 2 188 1.11E-44 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L01_01470 7f4e994542a3a54020eb3d8f95f53128 76 Gene3D G3DSA:2.40.330.20 1 74 4.6E-5 T 23-10-2018 IPR038619 MraZ superfamily A3L01_01470 7f4e994542a3a54020eb3d8f95f53128 76 SUPERFAMILY SSF89447 2 56 3.14E-8 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L01_01470 7f4e994542a3a54020eb3d8f95f53128 76 SMART SM00966 3 44 2.3E-4 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L01_03585 954768458112262d049ef89967b29a62 249 Pfam PF01925 Sulfite exporter TauE/SafE 8 241 4.1E-55 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A3L01_00325 d260ef0d1ee099558f7a664d86445106 113 SUPERFAMILY SSF46785 3 105 8.56E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_00325 d260ef0d1ee099558f7a664d86445106 113 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 12 83 1.1E-9 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L01_00325 d260ef0d1ee099558f7a664d86445106 113 Gene3D G3DSA:1.10.10.10 1 109 2.6E-36 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_05180 2bef48630bfb489634e017623e7a9add 330 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 15 323 1.6E-77 T 23-10-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 A3L01_05180 2bef48630bfb489634e017623e7a9add 330 Pfam PF02374 Anion-transporting ATPase 12 327 1.1E-75 T 23-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 A3L01_05180 2bef48630bfb489634e017623e7a9add 330 SMART SM00382 10 273 0.0014 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_05180 2bef48630bfb489634e017623e7a9add 330 Gene3D G3DSA:3.40.50.300 6 329 8.9E-90 T 23-10-2018 A3L01_05180 2bef48630bfb489634e017623e7a9add 330 SUPERFAMILY SSF52540 11 320 2.3E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_02835 3308cf4e8a0e523af1d915d5cbe3b84f 288 SUPERFAMILY SSF52768 16 286 6.3E-72 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily A3L01_02835 3308cf4e8a0e523af1d915d5cbe3b84f 288 Pfam PF00491 Arginase family 23 279 4.3E-61 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L01_02835 3308cf4e8a0e523af1d915d5cbe3b84f 288 TIGRFAM TIGR01230 agmatinase: agmatinase 20 280 2.1E-67 T 23-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 A3L01_02835 3308cf4e8a0e523af1d915d5cbe3b84f 288 Gene3D G3DSA:3.40.800.10 5 287 1.8E-74 T 23-10-2018 A3L01_02835 3308cf4e8a0e523af1d915d5cbe3b84f 288 PIRSF PIRSF036979 1 287 4.5E-82 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L01_01100 1b4903ac27bfba7bfc52cd2aaf60298e 183 Gene3D G3DSA:3.30.1440.10 10 182 5.5E-72 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01100 1b4903ac27bfba7bfc52cd2aaf60298e 183 SUPERFAMILY SSF55282 15 180 7.3E-56 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01100 1b4903ac27bfba7bfc52cd2aaf60298e 183 Pfam PF00673 ribosomal L5P family C-terminus 72 171 2.4E-26 T 23-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01100 1b4903ac27bfba7bfc52cd2aaf60298e 183 PIRSF PIRSF002161 2 180 7.0E-55 T 23-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01100 1b4903ac27bfba7bfc52cd2aaf60298e 183 Hamap MF_01333_A 50S ribosomal protein L5 [rplE]. 14 181 42.825 T 23-10-2018 IPR022804 Ribosomal protein L5, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01100 1b4903ac27bfba7bfc52cd2aaf60298e 183 Pfam PF00281 Ribosomal protein L5 16 68 8.7E-20 T 23-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_03955 1177195c8c1cb9f0f92c0d74985157e5 114 Pfam PF01934 Protein of unknown function DUF86 13 109 1.7E-29 T 23-10-2018 IPR008201 Protein of unknown function DUF86 A3L01_00025 ca8be00d562fdc35679455dd797e2978 712 TIGRFAM TIGR00376 TIGR00376: putative DNA helicase 19 655 5.8E-250 T 23-10-2018 IPR004483 Helicase SMUBP-2/Hcs1-like GO:0003677|GO:0005524 A3L01_00025 ca8be00d562fdc35679455dd797e2978 712 Gene3D G3DSA:3.40.50.300 452 662 4.1E-61 T 23-10-2018 A3L01_00025 ca8be00d562fdc35679455dd797e2978 712 Gene3D G3DSA:3.40.50.300 15 435 3.5E-94 T 23-10-2018 A3L01_00025 ca8be00d562fdc35679455dd797e2978 712 Pfam PF13087 AAA domain 429 630 5.1E-56 T 23-10-2018 A3L01_00025 ca8be00d562fdc35679455dd797e2978 712 Gene3D G3DSA:2.40.30.270 33 127 3.5E-94 T 23-10-2018 A3L01_00025 ca8be00d562fdc35679455dd797e2978 712 Pfam PF13086 AAA domain 174 424 1.4E-54 T 23-10-2018 A3L01_00025 ca8be00d562fdc35679455dd797e2978 712 SMART SM00487 171 453 0.0072 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L01_00025 ca8be00d562fdc35679455dd797e2978 712 SUPERFAMILY SSF52540 170 648 3.78E-66 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_08355 71bcc398db16a60b6778a86d6994a862 652 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 4 225 2.3E-40 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L01_08355 71bcc398db16a60b6778a86d6994a862 652 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 271 576 2.5E-18 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L01_08355 71bcc398db16a60b6778a86d6994a862 652 Gene3D G3DSA:3.60.9.10 1 228 7.4E-25 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L01_08355 71bcc398db16a60b6778a86d6994a862 652 Gene3D G3DSA:1.10.569.10 280 474 9.8E-13 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L01_08355 71bcc398db16a60b6778a86d6994a862 652 SMART SM00790 1 226 6.6E-72 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L01_08355 71bcc398db16a60b6778a86d6994a862 652 SUPERFAMILY SSF48310 253 650 6.41E-67 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L01_08355 71bcc398db16a60b6778a86d6994a862 652 SUPERFAMILY SSF56228 3 228 1.05E-44 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L01_00130 58cf092a171a90e31be94a37eef47afd 331 Gene3D G3DSA:3.40.50.20 1 85 1.1E-28 T 23-10-2018 A3L01_00130 58cf092a171a90e31be94a37eef47afd 331 SUPERFAMILY SSF52440 1 97 8.25E-31 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L01_00130 58cf092a171a90e31be94a37eef47afd 331 Hamap MF_01163 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [purP]. 1 331 49.163 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L01_00130 58cf092a171a90e31be94a37eef47afd 331 Pfam PF06849 Protein of unknown function (DUF1246) 3 117 2.4E-32 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L01_00130 58cf092a171a90e31be94a37eef47afd 331 Gene3D G3DSA:3.30.470.20 87 330 3.8E-98 T 23-10-2018 A3L01_00130 58cf092a171a90e31be94a37eef47afd 331 Pfam PF06973 Domain of unknown function (DUF1297) 150 331 1.6E-73 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L01_00130 58cf092a171a90e31be94a37eef47afd 331 PIRSF PIRSF004602 1 331 4.4E-131 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L01_00130 58cf092a171a90e31be94a37eef47afd 331 SUPERFAMILY SSF56059 101 331 1.85E-78 T 23-10-2018 A3L01_00130 58cf092a171a90e31be94a37eef47afd 331 Gene3D G3DSA:3.30.1490.20 114 174 3.8E-98 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L01_09320 a3a42c1f60fc94195d1c113f7333f105 370 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 3 273 6.9E-53 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 A3L01_09320 a3a42c1f60fc94195d1c113f7333f105 370 Pfam PF01494 FAD binding domain 3 168 5.5E-15 T 23-10-2018 IPR002938 FAD-binding domain GO:0071949 A3L01_09320 a3a42c1f60fc94195d1c113f7333f105 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 6.9E-12 T 23-10-2018 A3L01_09320 a3a42c1f60fc94195d1c113f7333f105 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 244 259 6.9E-12 T 23-10-2018 A3L01_09320 a3a42c1f60fc94195d1c113f7333f105 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 134 149 6.9E-12 T 23-10-2018 A3L01_09320 a3a42c1f60fc94195d1c113f7333f105 370 SUPERFAMILY SSF51905 3 282 1.76E-34 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_09320 a3a42c1f60fc94195d1c113f7333f105 370 Gene3D G3DSA:3.50.50.60 1 367 6.1E-58 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_04745 75f19b5c302f4a9d47036b5c76580d4d 288 SUPERFAMILY SSF48239 16 285 3.24E-16 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L01_04745 75f19b5c302f4a9d47036b5c76580d4d 288 PIRSF PIRSF016175 7 287 5.0E-129 T 23-10-2018 IPR016648 Uncharacterised conserved protein UCP016175, prenyltransferase beta-subunit-related A3L01_04165 c6d0d1772c54ae35a4ba2da3236e2de0 322 Pfam PF00155 Aminotransferase class I and II 24 314 3.6E-37 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L01_04165 c6d0d1772c54ae35a4ba2da3236e2de0 322 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 188 197 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A3L01_04165 c6d0d1772c54ae35a4ba2da3236e2de0 322 Gene3D G3DSA:3.40.640.10 30 233 7.3E-70 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L01_04165 c6d0d1772c54ae35a4ba2da3236e2de0 322 Gene3D G3DSA:3.90.1150.10 19 315 7.3E-70 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L01_04165 c6d0d1772c54ae35a4ba2da3236e2de0 322 SUPERFAMILY SSF53383 15 317 1.17E-55 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L01_07235 911b0c76b7eed5e617b3a0cbc8698558 134 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 48 111 1.5E-22 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal A3L01_07235 911b0c76b7eed5e617b3a0cbc8698558 134 SUPERFAMILY SSF50249 7 116 4.97E-33 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_07235 911b0c76b7eed5e617b3a0cbc8698558 134 Gene3D G3DSA:1.10.12.20 3 51 1.7E-5 T 23-10-2018 A3L01_07235 911b0c76b7eed5e617b3a0cbc8698558 134 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 20 47 2.8E-9 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 SMART SM00306 459 590 2.2E-25 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 Pfam PF14528 LAGLIDADG-like domain 700 788 9.5E-21 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 SUPERFAMILY SSF51294 460 842 7.85E-41 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 842 1162 7.6E-127 T 23-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 Pfam PF03477 ATP cone domain 5 93 4.1E-21 T 23-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 SMART SM00305 803 848 3.3E-9 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 113 268 6.1E-28 T 23-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 461 570 1.2E-17 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 PRINTS PR00379 Intein signature 700 712 6.8E-28 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 PRINTS PR00379 Intein signature 606 618 6.8E-28 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 PRINTS PR00379 Intein signature 837 846 6.8E-28 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 PRINTS PR00379 Intein signature 819 836 6.8E-28 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 PRINTS PR00379 Intein signature 557 570 6.8E-28 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 PRINTS PR00379 Intein signature 727 742 6.8E-28 T 23-10-2018 IPR006142 Intein GO:0016539 A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 Gene3D G3DSA:3.20.70.20 210 461 3.9E-78 T 23-10-2018 A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 Gene3D G3DSA:3.20.70.20 822 1168 3.4E-118 T 23-10-2018 A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 SUPERFAMILY SSF51998 270 1164 2.75E-149 T 23-10-2018 A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 Pfam PF02867 Ribonucleotide reductase, barrel domain 271 1153 3.2E-231 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 822 843 1.0E-8 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 SUPERFAMILY SSF48168 9 150 1.05E-11 T 23-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 Gene3D G3DSA:3.20.70.20 63 164 4.6E-6 T 23-10-2018 A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 Gene3D G3DSA:3.10.28.10 603 759 2.3E-32 T 23-10-2018 IPR027434 Homing endonuclease A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 SUPERFAMILY SSF55608 682 792 1.32E-18 T 23-10-2018 IPR027434 Homing endonuclease A3L01_10160 f5910a4130abc81380697f30daa4eed2 1290 Pfam PF14890 Intein splicing domain 541 842 1.0E-20 T 23-10-2018 A3L01_03330 9de4ad60d51944080cc8737627bc2af0 151 Pfam PF00312 Ribosomal protein S15 73 148 4.3E-20 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_03330 9de4ad60d51944080cc8737627bc2af0 151 SMART SM01387 70 149 1.5E-25 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_03330 9de4ad60d51944080cc8737627bc2af0 151 Gene3D G3DSA:1.10.8.1030 36 82 8.3E-21 T 23-10-2018 A3L01_03330 9de4ad60d51944080cc8737627bc2af0 151 Gene3D G3DSA:1.10.287.10 83 151 4.1E-32 T 23-10-2018 A3L01_03330 9de4ad60d51944080cc8737627bc2af0 151 SMART SM01386 1 60 1.7E-34 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_03330 9de4ad60d51944080cc8737627bc2af0 151 SUPERFAMILY SSF47060 66 142 1.24E-24 T 23-10-2018 IPR009068 S15/NS1, RNA-binding A3L01_03330 9de4ad60d51944080cc8737627bc2af0 151 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 91 132 5.0E-4 T 23-10-2018 A3L01_03330 9de4ad60d51944080cc8737627bc2af0 151 Hamap MF_01343_A 30S ribosomal protein S15 [rpsO]. 3 149 37.57 T 23-10-2018 IPR023029 Ribosomal protein S15P Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_03330 9de4ad60d51944080cc8737627bc2af0 151 ProSitePatterns PS00362 Ribosomal protein S15 signature. 98 128 - T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_03330 9de4ad60d51944080cc8737627bc2af0 151 Pfam PF08069 Ribosomal S13/S15 N-terminal domain 1 60 4.2E-27 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01155 7d14ba4068315f84feace57f3b600acc 196 Pfam PF13207 AAA domain 8 145 2.7E-37 T 23-10-2018 A3L01_01155 7d14ba4068315f84feace57f3b600acc 196 SUPERFAMILY SSF52540 1 188 4.04E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_01155 7d14ba4068315f84feace57f3b600acc 196 Hamap MF_00234 Adenylate kinase [adkA]. 3 189 44.635 T 23-10-2018 IPR023477 Adenylate kinase AdkA GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A3L01_01155 7d14ba4068315f84feace57f3b600acc 196 Gene3D G3DSA:3.40.50.300 3 189 2.8E-56 T 23-10-2018 A3L01_00400 222de4cac7e85e047bb87f4e3eccfcd1 344 TIGRFAM TIGR00322 diphth2_R: diphthamide biosynthesis enzyme Dph1/Dph2 domain 7 313 1.6E-89 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L01_00400 222de4cac7e85e047bb87f4e3eccfcd1 344 Gene3D G3DSA:3.40.50.11860 212 313 6.4E-33 T 23-10-2018 A3L01_00400 222de4cac7e85e047bb87f4e3eccfcd1 344 Gene3D G3DSA:3.40.50.11850 100 208 4.4E-40 T 23-10-2018 A3L01_00400 222de4cac7e85e047bb87f4e3eccfcd1 344 TIGRFAM TIGR03682 arCOG04112: diphthamide biosynthesis enzyme Dph2 18 324 2.1E-111 T 23-10-2018 IPR022428 Diphthamide synthesis Dph2, archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546 A3L01_00400 222de4cac7e85e047bb87f4e3eccfcd1 344 Gene3D G3DSA:3.40.50.11840 5 98 2.1E-30 T 23-10-2018 A3L01_00400 222de4cac7e85e047bb87f4e3eccfcd1 344 PIRSF PIRSF004967 2 338 2.8E-80 T 23-10-2018 IPR035435 Diphthamide synthesis DHP1/DPH2, eukaryotes and archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L01_00400 222de4cac7e85e047bb87f4e3eccfcd1 344 Pfam PF01866 Putative diphthamide synthesis protein 26 319 3.3E-75 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L01_05690 288ec410d4a633064b532f7cded438ad 350 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 329 348 7.1E-7 T 23-10-2018 IPR027552 CGP-CTERM domain A3L01_05690 288ec410d4a633064b532f7cded438ad 350 ProDom PD117176 AQ_1776 58 174 0.001 T 23-10-2018 A3L01_07490 a67339e8703503dfc6914837a50a82a2 239 Pfam PF06508 Queuosine biosynthesis protein QueC 3 225 3.6E-64 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L01_07490 a67339e8703503dfc6914837a50a82a2 239 Gene3D G3DSA:3.40.50.620 1 237 2.2E-61 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_07490 a67339e8703503dfc6914837a50a82a2 239 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 2 231 46.243 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L01_07490 a67339e8703503dfc6914837a50a82a2 239 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 4 218 1.1E-48 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L01_07490 a67339e8703503dfc6914837a50a82a2 239 PIRSF PIRSF006293 1 237 1.8E-70 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L01_07490 a67339e8703503dfc6914837a50a82a2 239 SUPERFAMILY SSF52402 1 234 2.51E-50 T 23-10-2018 A3L01_05800 bd941afd012fc3185789e0fe986a0252 472 Gene3D G3DSA:3.40.50.261 142 306 2.3E-59 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L01_05800 bd941afd012fc3185789e0fe986a0252 472 Gene3D G3DSA:3.40.50.261 310 470 5.9E-51 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L01_05800 bd941afd012fc3185789e0fe986a0252 472 SUPERFAMILY SSF52210 311 468 2.35E-40 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L01_05800 bd941afd012fc3185789e0fe986a0252 472 Pfam PF13380 CoA binding domain 16 145 5.0E-25 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L01_05800 bd941afd012fc3185789e0fe986a0252 472 SUPERFAMILY SSF51735 10 141 8.31E-39 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_05800 bd941afd012fc3185789e0fe986a0252 472 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 167 303 2.0E-55 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L01_05800 bd941afd012fc3185789e0fe986a0252 472 SMART SM00881 12 111 2.1E-36 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L01_05800 bd941afd012fc3185789e0fe986a0252 472 Gene3D G3DSA:3.40.50.720 9 140 5.4E-43 T 23-10-2018 A3L01_05800 bd941afd012fc3185789e0fe986a0252 472 SUPERFAMILY SSF52210 143 304 3.79E-44 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L01_05025 ef9cc099fc37272a9f23d1f8f0b6a916 183 Gene3D G3DSA:1.20.1260.10 4 160 1.4E-63 T 23-10-2018 IPR012347 Ferritin-like A3L01_05025 ef9cc099fc37272a9f23d1f8f0b6a916 183 PIRSF PIRSF018063 1 168 7.7E-69 T 23-10-2018 IPR014490 DNA-binding protein from starved cells-like A3L01_05025 ef9cc099fc37272a9f23d1f8f0b6a916 183 SUPERFAMILY SSF47240 4 159 2.32E-29 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L01_05025 ef9cc099fc37272a9f23d1f8f0b6a916 183 Pfam PF00210 Ferritin-like domain 21 160 3.1E-22 T 23-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A3L01_09590 9842204758c1de7f3eab3faa21e823c1 437 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 17 384 26.778 T 23-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 A3L01_09590 9842204758c1de7f3eab3faa21e823c1 437 SUPERFAMILY SSF52954 341 435 4.98E-22 T 23-10-2018 A3L01_09590 9842204758c1de7f3eab3faa21e823c1 437 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 7 422 2.9E-126 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A3L01_09590 9842204758c1de7f3eab3faa21e823c1 437 Gene3D G3DSA:3.30.930.10 1 329 5.7E-110 T 23-10-2018 A3L01_09590 9842204758c1de7f3eab3faa21e823c1 437 PIRSF PIRSF001549 1 435 3.1E-139 T 23-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 A3L01_09590 9842204758c1de7f3eab3faa21e823c1 437 Pfam PF03129 Anticodon binding domain 342 433 1.2E-18 T 23-10-2018 IPR004154 Anticodon-binding A3L01_09590 9842204758c1de7f3eab3faa21e823c1 437 Pfam PF13393 Histidyl-tRNA synthetase 10 324 1.3E-67 T 23-10-2018 A3L01_09590 9842204758c1de7f3eab3faa21e823c1 437 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 3 433 31.062 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A3L01_09590 9842204758c1de7f3eab3faa21e823c1 437 SUPERFAMILY SSF55681 7 335 1.91E-87 T 23-10-2018 A3L01_09590 9842204758c1de7f3eab3faa21e823c1 437 Gene3D G3DSA:3.40.50.800 334 434 2.8E-24 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A3L01_09590 9842204758c1de7f3eab3faa21e823c1 437 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 12 327 3.1E-85 T 23-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 A3L01_09425 43f2358de89b026fcc3f6f6021880ae6 476 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 17 423 1.6E-60 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A3L01_09425 43f2358de89b026fcc3f6f6021880ae6 476 SUPERFAMILY SSF53649 15 462 3.27E-36 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L01_09425 43f2358de89b026fcc3f6f6021880ae6 476 Gene3D G3DSA:3.40.720.10 4 297 2.6E-48 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L01_04175 e8d77f68c3c00df22d39a508acae6ffe 248 SMART SM00987 104 240 4.1E-9 T 23-10-2018 A3L01_04175 e8d77f68c3c00df22d39a508acae6ffe 248 SUPERFAMILY SSF52141 100 242 3.92E-24 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L01_04175 e8d77f68c3c00df22d39a508acae6ffe 248 Pfam PF03167 Uracil DNA glycosylase superfamily 107 223 5.9E-20 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L01_04175 e8d77f68c3c00df22d39a508acae6ffe 248 SMART SM00986 104 240 4.1E-9 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L01_04175 e8d77f68c3c00df22d39a508acae6ffe 248 Gene3D G3DSA:3.40.470.10 59 244 8.0E-25 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L01_01845 7f06c6f9ff96d5a66273cc3b336f2e21 59 SUPERFAMILY SSF144210 4 51 7.19E-22 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 A3L01_01845 7f06c6f9ff96d5a66273cc3b336f2e21 59 Pfam PF04135 Nucleolar RNA-binding protein, Nop10p family 1 51 6.0E-28 T 23-10-2018 IPR007264 H/ACA ribonucleoprotein complex, subunit Nop10 GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 A3L01_01845 7f06c6f9ff96d5a66273cc3b336f2e21 59 Gene3D G3DSA:2.20.28.40 1 59 4.5E-31 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 A3L01_01845 7f06c6f9ff96d5a66273cc3b336f2e21 59 Hamap MF_00803 Ribosome biogenesis protein Nop10 [nop10]. 3 53 21.183 T 23-10-2018 IPR023532 H/ACA ribonucleoprotein complex subunit Nop10 , archaeal-type GO:0001522|GO:0030515|GO:0042254 A3L01_03230 677d61e57dadd685be8d0801fb95ac39 377 SUPERFAMILY SSF53756 2 365 6.22E-123 T 23-10-2018 A3L01_03230 677d61e57dadd685be8d0801fb95ac39 377 Gene3D G3DSA:3.40.50.2000 6 357 5.9E-136 T 23-10-2018 A3L01_03230 677d61e57dadd685be8d0801fb95ac39 377 Gene3D G3DSA:3.40.50.2000 183 347 5.9E-136 T 23-10-2018 A3L01_03230 677d61e57dadd685be8d0801fb95ac39 377 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 25 360 1.8E-118 T 23-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A3L01_03230 677d61e57dadd685be8d0801fb95ac39 377 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 3 361 1.7E-129 T 23-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 A3L01_04665 8f9f31ae7a48ca60624e7c32b687339a 602 SUPERFAMILY SSF56235 2 229 7.03E-75 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L01_04665 8f9f31ae7a48ca60624e7c32b687339a 602 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 602 5.1E-245 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A3L01_04665 8f9f31ae7a48ca60624e7c32b687339a 602 SUPERFAMILY SSF53697 247 602 1.11E-111 T 23-10-2018 A3L01_04665 8f9f31ae7a48ca60624e7c32b687339a 602 Pfam PF13522 Glutamine amidotransferase domain 67 187 2.5E-22 T 23-10-2018 A3L01_04665 8f9f31ae7a48ca60624e7c32b687339a 602 Gene3D G3DSA:3.40.50.10490 442 587 1.7E-136 T 23-10-2018 A3L01_04665 8f9f31ae7a48ca60624e7c32b687339a 602 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 602 40.952 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A3L01_04665 8f9f31ae7a48ca60624e7c32b687339a 602 Pfam PF01380 SIS domain 457 584 4.7E-23 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A3L01_04665 8f9f31ae7a48ca60624e7c32b687339a 602 Pfam PF01380 SIS domain 284 412 6.4E-32 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A3L01_04665 8f9f31ae7a48ca60624e7c32b687339a 602 Gene3D G3DSA:3.60.20.10 2 241 4.6E-78 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L01_04665 8f9f31ae7a48ca60624e7c32b687339a 602 Gene3D G3DSA:3.40.50.10490 250 601 1.7E-136 T 23-10-2018 A3L01_03560 9bbc87354d38770249ad945407477405 482 PRINTS PR01046 Prolyl-tRNA synthetase signature 65 83 1.9E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A3L01_03560 9bbc87354d38770249ad945407477405 482 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 1.9E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A3L01_03560 9bbc87354d38770249ad945407477405 482 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 1.9E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A3L01_03560 9bbc87354d38770249ad945407477405 482 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 1.9E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A3L01_03560 9bbc87354d38770249ad945407477405 482 SUPERFAMILY SSF52954 279 403 6.64E-37 T 23-10-2018 A3L01_03560 9bbc87354d38770249ad945407477405 482 Gene3D G3DSA:3.30.930.10 12 283 5.4E-86 T 23-10-2018 A3L01_03560 9bbc87354d38770249ad945407477405 482 Gene3D G3DSA:3.30.110.30 405 481 1.9E-18 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L01_03560 9bbc87354d38770249ad945407477405 482 SUPERFAMILY SSF55681 11 277 4.02E-76 T 23-10-2018 A3L01_03560 9bbc87354d38770249ad945407477405 482 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 412 482 2.8E-16 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L01_03560 9bbc87354d38770249ad945407477405 482 Gene3D G3DSA:3.40.50.800 284 402 2.1E-36 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A3L01_03560 9bbc87354d38770249ad945407477405 482 Pfam PF03129 Anticodon binding domain 290 384 1.4E-21 T 23-10-2018 IPR004154 Anticodon-binding A3L01_03560 9bbc87354d38770249ad945407477405 482 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 100 272 9.7E-25 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_03560 9bbc87354d38770249ad945407477405 482 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 10 482 1.6E-178 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L01_03560 9bbc87354d38770249ad945407477405 482 Hamap MF_01571 Proline--tRNA ligase [proS]. 6 482 41.089 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L01_03560 9bbc87354d38770249ad945407477405 482 SMART SM00946 411 482 2.0E-25 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L01_03560 9bbc87354d38770249ad945407477405 482 SUPERFAMILY SSF64586 406 482 8.63E-21 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L01_09175 959794b90d1104333d4bcaebbf8774ed 191 Pfam PF12840 Helix-turn-helix domain 11 67 7.3E-15 T 23-10-2018 A3L01_09175 959794b90d1104333d4bcaebbf8774ed 191 SUPERFAMILY SSF46785 1 165 2.26E-34 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_09175 959794b90d1104333d4bcaebbf8774ed 191 Gene3D G3DSA:1.10.10.10 1 89 5.4E-31 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_09175 959794b90d1104333d4bcaebbf8774ed 191 SMART SM00418 11 113 1.8E-8 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_09175 959794b90d1104333d4bcaebbf8774ed 191 Gene3D G3DSA:1.10.20.10 90 191 2.0E-49 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L01_06815 7f0727fd17a31bbea741e78a9291a609 280 SUPERFAMILY SSF53613 1 265 1.87E-37 T 23-10-2018 IPR029056 Ribokinase-like A3L01_06815 7f0727fd17a31bbea741e78a9291a609 280 Gene3D G3DSA:3.40.1190.20 1 275 5.2E-90 T 23-10-2018 IPR029056 Ribokinase-like A3L01_06815 7f0727fd17a31bbea741e78a9291a609 280 Pfam PF00294 pfkB family carbohydrate kinase 178 259 1.4E-6 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A3L01_05065 89e3d7b67e6d34b9792b3e37e6b0430f 247 Pfam PF12730 ABC-2 family transporter protein 55 176 5.1E-9 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A3L01_01580 27ff2f400a163909e7cd43395c3ff5af 222 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 15 218 9.7E-76 T 23-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A3L01_01580 27ff2f400a163909e7cd43395c3ff5af 222 SUPERFAMILY SSF53271 13 217 4.33E-56 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L01_01580 27ff2f400a163909e7cd43395c3ff5af 222 Hamap MF_01218_A Uracil phosphoribosyltransferase [upp]. 9 217 40.17 T 23-10-2018 IPR034331 Uracil phosphoribosyltransferase, archaea GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A3L01_01580 27ff2f400a163909e7cd43395c3ff5af 222 Pfam PF14681 Uracil phosphoribosyltransferase 15 218 6.1E-50 T 23-10-2018 A3L01_01580 27ff2f400a163909e7cd43395c3ff5af 222 Gene3D G3DSA:3.40.50.2020 13 219 6.4E-58 T 23-10-2018 A3L01_08050 246fb420020ca8c70abadc98d8f85894 169 Gene3D G3DSA:1.10.10.10 1 61 8.1E-15 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_08050 246fb420020ca8c70abadc98d8f85894 169 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 46 3.0E-8 T 23-10-2018 A3L01_08050 246fb420020ca8c70abadc98d8f85894 169 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 2.3E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_08050 246fb420020ca8c70abadc98d8f85894 169 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 117 132 2.3E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_08050 246fb420020ca8c70abadc98d8f85894 169 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 102 117 2.3E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_08050 246fb420020ca8c70abadc98d8f85894 169 SUPERFAMILY SSF46785 4 58 1.45E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_08050 246fb420020ca8c70abadc98d8f85894 169 Pfam PF01022 Bacterial regulatory protein, arsR family 76 120 3.9E-14 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_08050 246fb420020ca8c70abadc98d8f85894 169 Gene3D G3DSA:1.10.10.10 62 150 5.8E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_08050 246fb420020ca8c70abadc98d8f85894 169 SUPERFAMILY SSF46785 68 154 2.26E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_08050 246fb420020ca8c70abadc98d8f85894 169 SMART SM00419 82 132 8.9E-4 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L01_08050 246fb420020ca8c70abadc98d8f85894 169 SMART SM00418 68 148 1.8E-19 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_01740 30c97063d078e6ae4df1477a04425134 373 Gene3D G3DSA:3.40.50.1980 174 369 2.7E-85 T 23-10-2018 A3L01_01740 30c97063d078e6ae4df1477a04425134 373 Gene3D G3DSA:3.40.50.1980 27 173 4.5E-58 T 23-10-2018 A3L01_01740 30c97063d078e6ae4df1477a04425134 373 SUPERFAMILY SSF53807 37 349 7.85E-58 T 23-10-2018 A3L01_01740 30c97063d078e6ae4df1477a04425134 373 Pfam PF01497 Periplasmic binding protein 53 294 4.3E-27 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain A3L01_00060 34faec15e0d8e777bd15ea95f9653753 197 ProSitePatterns PS01236 PdxT/SNO family family signature. 47 57 - T 23-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L01_00060 34faec15e0d8e777bd15ea95f9653753 197 SUPERFAMILY SSF52317 3 194 1.67E-50 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_00060 34faec15e0d8e777bd15ea95f9653753 197 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 3 193 2.4E-73 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L01_00060 34faec15e0d8e777bd15ea95f9653753 197 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 195 36.181 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L01_00060 34faec15e0d8e777bd15ea95f9653753 197 Pfam PF01174 SNO glutamine amidotransferase family 6 195 2.7E-59 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L01_00060 34faec15e0d8e777bd15ea95f9653753 197 Gene3D G3DSA:3.40.50.880 1 197 1.1E-69 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_00060 34faec15e0d8e777bd15ea95f9653753 197 PIRSF PIRSF005639 1 197 5.9E-69 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L01_01705 99e242ec1c3e47267c2c9c7d0555d711 243 Gene3D G3DSA:3.40.50.300 1 224 3.1E-64 T 23-10-2018 A3L01_01705 99e242ec1c3e47267c2c9c7d0555d711 243 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 17 234 4.2E-54 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 A3L01_01705 99e242ec1c3e47267c2c9c7d0555d711 243 SUPERFAMILY SSF52540 16 219 1.27E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_01705 99e242ec1c3e47267c2c9c7d0555d711 243 Hamap MF_02040 Iron-sulfur cluster carrier protein. 9 237 27.437 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein A3L01_06550 b1efd08e6d3ad2b8c6149e993e65a7de 122 Hamap MF_00757 Ribonuclease P protein component 4 [rnp4]. 10 106 25.803 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 A3L01_06550 b1efd08e6d3ad2b8c6149e993e65a7de 122 Pfam PF04032 RNAse P Rpr2/Rpp21/SNM1 subunit domain 21 97 6.9E-17 T 23-10-2018 IPR007175 RNAse P, Rpr2/Rpp21 subunit Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L01_06550 b1efd08e6d3ad2b8c6149e993e65a7de 122 Gene3D G3DSA:2.20.25.200 64 116 1.1E-22 T 23-10-2018 A3L01_06550 b1efd08e6d3ad2b8c6149e993e65a7de 122 PIRSF PIRSF004878 1 113 2.3E-43 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 A3L01_06550 b1efd08e6d3ad2b8c6149e993e65a7de 122 Gene3D G3DSA:1.20.5.420 5 63 5.5E-20 T 23-10-2018 A3L01_00450 ff4581e16581708859a2af75c062db09 256 Gene3D G3DSA:1.10.3210.10 32 201 7.2E-7 T 23-10-2018 A3L01_00450 ff4581e16581708859a2af75c062db09 256 SUPERFAMILY SSF109604 49 170 2.28E-8 T 23-10-2018 A3L01_03665 01c89b43b36a2a82c194c1a0355a7a3c 90 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 71 82 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_03665 01c89b43b36a2a82c194c1a0355a7a3c 90 SUPERFAMILY SSF54862 21 89 1.68E-15 T 23-10-2018 A3L01_03665 01c89b43b36a2a82c194c1a0355a7a3c 90 Gene3D G3DSA:3.30.70.20 1 90 3.1E-17 T 23-10-2018 A3L01_03665 01c89b43b36a2a82c194c1a0355a7a3c 90 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 34 45 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_03665 01c89b43b36a2a82c194c1a0355a7a3c 90 Pfam PF12838 4Fe-4S dicluster domain 34 82 3.2E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_09525 4699878e062ee8d75d87c3751f736fdd 232 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 195 1.9E-20 T 23-10-2018 A3L01_09525 4699878e062ee8d75d87c3751f736fdd 232 Gene3D G3DSA:3.40.50.1000 3 217 3.5E-39 T 23-10-2018 IPR023214 HAD superfamily A3L01_09525 4699878e062ee8d75d87c3751f736fdd 232 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 91 189 9.8E-13 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_09525 4699878e062ee8d75d87c3751f736fdd 232 Gene3D G3DSA:1.10.150.520 14 96 3.5E-39 T 23-10-2018 A3L01_09525 4699878e062ee8d75d87c3751f736fdd 232 SUPERFAMILY SSF56784 3 223 1.6E-37 T 23-10-2018 IPR036412 HAD-like superfamily A3L01_01545 897fd9687ecf70fb1a34750ce8ecb8f5 387 Gene3D G3DSA:3.40.50.300 1 183 1.8E-12 T 23-10-2018 A3L01_04310 94a391c957eeed67ba4c1c50d0a6baa4 551 Gene3D G3DSA:3.30.260.10 147 405 7.9E-218 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A3L01_04310 94a391c957eeed67ba4c1c50d0a6baa4 551 SUPERFAMILY SSF52029 212 378 1.74E-63 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily A3L01_04310 94a391c957eeed67ba4c1c50d0a6baa4 551 Gene3D G3DSA:3.50.7.10 218 369 7.9E-218 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily A3L01_04310 94a391c957eeed67ba4c1c50d0a6baa4 551 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 89 97 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L01_04310 94a391c957eeed67ba4c1c50d0a6baa4 551 SUPERFAMILY SSF48592 17 523 3.27E-91 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily A3L01_04310 94a391c957eeed67ba4c1c50d0a6baa4 551 SUPERFAMILY SSF54849 149 405 2.04E-31 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A3L01_04310 94a391c957eeed67ba4c1c50d0a6baa4 551 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 61 77 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L01_04310 94a391c957eeed67ba4c1c50d0a6baa4 551 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 40 52 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L01_04310 94a391c957eeed67ba4c1c50d0a6baa4 551 Pfam PF00118 TCP-1/cpn60 chaperonin family 35 525 2.9E-183 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 A3L01_04310 94a391c957eeed67ba4c1c50d0a6baa4 551 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 8 525 4.1E-237 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 A3L01_04310 94a391c957eeed67ba4c1c50d0a6baa4 551 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 59 77 2.0E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L01_04310 94a391c957eeed67ba4c1c50d0a6baa4 551 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 37 53 2.0E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L01_04310 94a391c957eeed67ba4c1c50d0a6baa4 551 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 89 108 2.0E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L01_04310 94a391c957eeed67ba4c1c50d0a6baa4 551 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 407 419 2.0E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L01_04310 94a391c957eeed67ba4c1c50d0a6baa4 551 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 373 395 2.0E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L01_04310 94a391c957eeed67ba4c1c50d0a6baa4 551 Gene3D G3DSA:1.10.560.10 28 522 7.9E-218 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily A3L01_00605 f8cd33a1d8ca4b9078659223739e20ec 452 Pfam PF01029 NusB family 10 133 3.0E-19 T 23-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A3L01_00605 f8cd33a1d8ca4b9078659223739e20ec 452 Gene3D G3DSA:1.10.940.10 6 150 3.9E-14 T 23-10-2018 IPR035926 NusB-like superfamily A3L01_00605 f8cd33a1d8ca4b9078659223739e20ec 452 Gene3D G3DSA:3.40.50.150 154 450 1.3E-80 T 23-10-2018 A3L01_00605 f8cd33a1d8ca4b9078659223739e20ec 452 Pfam PF01189 16S rRNA methyltransferase RsmB/F 255 449 2.1E-49 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L01_00605 f8cd33a1d8ca4b9078659223739e20ec 452 SUPERFAMILY SSF48013 9 163 9.94E-24 T 23-10-2018 IPR035926 NusB-like superfamily A3L01_00605 f8cd33a1d8ca4b9078659223739e20ec 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 433 450 3.5E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_00605 f8cd33a1d8ca4b9078659223739e20ec 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 266 276 3.5E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_00605 f8cd33a1d8ca4b9078659223739e20ec 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 381 397 3.5E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_00605 f8cd33a1d8ca4b9078659223739e20ec 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 237 251 3.5E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_00605 f8cd33a1d8ca4b9078659223739e20ec 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 331 343 3.5E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L01_00605 f8cd33a1d8ca4b9078659223739e20ec 452 SUPERFAMILY SSF53335 148 450 1.45E-72 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_01055 bd10b16de20043447303a50f7574d616 156 ProSitePatterns PS00464 Ribosomal protein L22 signature. 127 151 - T 23-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01055 bd10b16de20043447303a50f7574d616 156 Pfam PF00237 Ribosomal protein L22p/L17e 21 151 5.8E-35 T 23-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 A3L01_01055 bd10b16de20043447303a50f7574d616 156 Hamap MF_01331_A 50S ribosomal protein L22 [rplV]. 4 154 33.948 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01055 bd10b16de20043447303a50f7574d616 156 Gene3D G3DSA:3.90.470.10 6 156 1.2E-53 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 A3L01_01055 bd10b16de20043447303a50f7574d616 156 TIGRFAM TIGR01038 uL22_arch_euk: ribosomal protein uL22 8 153 4.2E-67 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01055 bd10b16de20043447303a50f7574d616 156 SUPERFAMILY SSF54843 8 153 3.01E-47 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 A3L01_07335 b8c3029106b86dd10b853e76b2ee4532 150 SMART SM00344 5 111 2.4E-48 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L01_07335 b8c3029106b86dd10b853e76b2ee4532 150 SUPERFAMILY SSF54909 65 150 4.02E-22 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L01_07335 b8c3029106b86dd10b853e76b2ee4532 150 Gene3D G3DSA:3.30.70.920 57 150 1.2E-27 T 23-10-2018 A3L01_07335 b8c3029106b86dd10b853e76b2ee4532 150 SUPERFAMILY SSF46785 5 65 1.17E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_07335 b8c3029106b86dd10b853e76b2ee4532 150 Pfam PF01037 Lrp/AsnC ligand binding domain 71 140 6.3E-19 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L01_07335 b8c3029106b86dd10b853e76b2ee4532 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 2.8E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_07335 b8c3029106b86dd10b853e76b2ee4532 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 2.8E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_07335 b8c3029106b86dd10b853e76b2ee4532 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 2.8E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_07335 b8c3029106b86dd10b853e76b2ee4532 150 Pfam PF13404 AsnC-type helix-turn-helix domain 5 46 9.2E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_07335 b8c3029106b86dd10b853e76b2ee4532 150 Gene3D G3DSA:1.10.10.10 2 55 2.8E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_08640 ffb56bee0d8dd0efb8979122ed44f7d7 118 Pfam PF07883 Cupin domain 38 104 2.0E-15 T 23-10-2018 IPR013096 Cupin 2, conserved barrel A3L01_08640 ffb56bee0d8dd0efb8979122ed44f7d7 118 SUPERFAMILY SSF51182 5 105 4.59E-27 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L01_08640 ffb56bee0d8dd0efb8979122ed44f7d7 118 Gene3D G3DSA:2.60.120.10 4 117 4.6E-33 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L01_01595 399c018488917eab1d36e24439a7f85e 784 Gene3D G3DSA:3.20.20.60 463 783 1.7E-103 T 23-10-2018 A3L01_01595 399c018488917eab1d36e24439a7f85e 784 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 729 741 6.5E-14 T 23-10-2018 A3L01_01595 399c018488917eab1d36e24439a7f85e 784 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 512 531 6.5E-14 T 23-10-2018 A3L01_01595 399c018488917eab1d36e24439a7f85e 784 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 676 691 6.5E-14 T 23-10-2018 A3L01_01595 399c018488917eab1d36e24439a7f85e 784 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 693 708 6.5E-14 T 23-10-2018 A3L01_01595 399c018488917eab1d36e24439a7f85e 784 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 413 424 - T 23-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 A3L01_01595 399c018488917eab1d36e24439a7f85e 784 SUPERFAMILY SSF52009 354 462 5.62E-37 T 23-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 A3L01_01595 399c018488917eab1d36e24439a7f85e 784 Gene3D G3DSA:3.30.470.20 198 353 3.9E-54 T 23-10-2018 A3L01_01595 399c018488917eab1d36e24439a7f85e 784 SUPERFAMILY SSF51621 485 778 2.88E-94 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A3L01_01595 399c018488917eab1d36e24439a7f85e 784 Gene3D G3DSA:3.50.30.10 354 462 3.7E-43 T 23-10-2018 A3L01_01595 399c018488917eab1d36e24439a7f85e 784 Gene3D G3DSA:3.30.1490.20 3 197 1.2E-72 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L01_01595 399c018488917eab1d36e24439a7f85e 784 SUPERFAMILY SSF56059 3 382 4.0E-108 T 23-10-2018 A3L01_01595 399c018488917eab1d36e24439a7f85e 784 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 19 344 6.2E-119 T 23-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 A3L01_01595 399c018488917eab1d36e24439a7f85e 784 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 473 770 6.5E-97 T 23-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A3L01_01595 399c018488917eab1d36e24439a7f85e 784 PIRSF PIRSF000854 1 775 5.2E-207 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 A3L01_01595 399c018488917eab1d36e24439a7f85e 784 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 7 771 5.2E-290 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 A3L01_01595 399c018488917eab1d36e24439a7f85e 784 Pfam PF00391 PEP-utilising enzyme, mobile domain 382 454 8.0E-29 T 23-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A3L01_01595 399c018488917eab1d36e24439a7f85e 784 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 676 694 - T 23-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 A3L01_03415 d9c546e30bfba2215f51e632b74f94d2 429 SUPERFAMILY SSF56762 8 425 4.71E-93 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_03415 d9c546e30bfba2215f51e632b74f94d2 429 Gene3D G3DSA:1.10.645.10 6 425 6.5E-103 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_03415 d9c546e30bfba2215f51e632b74f94d2 429 Pfam PF00374 Nickel-dependent hydrogenase 306 425 3.4E-9 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L01_03415 d9c546e30bfba2215f51e632b74f94d2 429 Pfam PF00374 Nickel-dependent hydrogenase 43 128 4.9E-12 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L01_03415 d9c546e30bfba2215f51e632b74f94d2 429 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 416 425 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 A3L01_08080 998663372511b964cea962f652f85848 425 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 236 403 7.6E-33 T 23-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 A3L01_08080 998663372511b964cea962f652f85848 425 SUPERFAMILY SSF52402 224 392 2.39E-33 T 23-10-2018 A3L01_08080 998663372511b964cea962f652f85848 425 Gene3D G3DSA:3.40.50.620 217 408 3.6E-36 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_07630 f232e77cdf7ac6e6c773d2d3a3146dc0 440 SUPERFAMILY SSF53448 220 423 5.98E-32 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_07630 f232e77cdf7ac6e6c773d2d3a3146dc0 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 172 185 1.6E-5 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_07630 f232e77cdf7ac6e6c773d2d3a3146dc0 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.6E-5 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_07630 f232e77cdf7ac6e6c773d2d3a3146dc0 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 94 107 1.6E-5 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_07630 f232e77cdf7ac6e6c773d2d3a3146dc0 440 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 182 2.7E-19 T 23-10-2018 A3L01_07630 f232e77cdf7ac6e6c773d2d3a3146dc0 440 Gene3D G3DSA:1.10.150.240 21 80 6.3E-27 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A3L01_07630 f232e77cdf7ac6e6c773d2d3a3146dc0 440 SUPERFAMILY SSF56784 2 217 2.23E-34 T 23-10-2018 IPR036412 HAD-like superfamily A3L01_07630 f232e77cdf7ac6e6c773d2d3a3146dc0 440 Gene3D G3DSA:3.90.550.10 214 436 5.5E-46 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_07630 f232e77cdf7ac6e6c773d2d3a3146dc0 440 Gene3D G3DSA:3.40.50.1000 6 184 6.3E-27 T 23-10-2018 IPR023214 HAD superfamily A3L01_07630 f232e77cdf7ac6e6c773d2d3a3146dc0 440 Pfam PF00535 Glycosyl transferase family 2 221 343 8.6E-24 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L01_05000 fbfdc66c1a6f1225c252bf45ab87bb4f 115 Gene3D G3DSA:3.30.300.130 23 106 1.5E-12 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L01_05000 fbfdc66c1a6f1225c252bf45ab87bb4f 115 Pfam PF01883 Iron-sulfur cluster assembly protein 26 87 4.8E-10 T 23-10-2018 IPR002744 MIP18 family-like A3L01_05000 fbfdc66c1a6f1225c252bf45ab87bb4f 115 SUPERFAMILY SSF117916 25 88 4.9E-11 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L01_02730 bf6b6ec89d7873b2f21eaa6591e060da 120 Gene3D G3DSA:1.10.150.80 55 120 1.4E-27 T 23-10-2018 A3L01_02730 bf6b6ec89d7873b2f21eaa6591e060da 120 Gene3D G3DSA:1.10.287.420 1 54 6.9E-36 T 23-10-2018 A3L01_02730 bf6b6ec89d7873b2f21eaa6591e060da 120 SUPERFAMILY SSF47819 1 115 9.16E-24 T 23-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 A3L01_02730 bf6b6ec89d7873b2f21eaa6591e060da 120 PIRSF PIRSF005053 1 120 4.2E-29 T 23-10-2018 IPR010924 DNA-directed RNA polymerase subunit F (Rpo4) A3L01_02730 bf6b6ec89d7873b2f21eaa6591e060da 120 Pfam PF03874 RNA polymerase Rpb4 11 118 9.5E-7 T 23-10-2018 IPR005574 RNA polymerase subunit RPB4/RPC9 GO:0006352|GO:0030880 A3L01_02820 5c71b47b62a3ddc8164fa9b57282337e 164 Gene3D G3DSA:3.10.580.10 1 73 4.6E-7 T 23-10-2018 A3L01_02820 5c71b47b62a3ddc8164fa9b57282337e 164 Pfam PF00571 CBS domain 99 152 6.6E-9 T 23-10-2018 IPR000644 CBS domain A3L01_02820 5c71b47b62a3ddc8164fa9b57282337e 164 Pfam PF00571 CBS domain 26 72 1.6E-5 T 23-10-2018 IPR000644 CBS domain A3L01_02820 5c71b47b62a3ddc8164fa9b57282337e 164 SMART SM00116 105 152 1.2E-5 T 23-10-2018 IPR000644 CBS domain A3L01_02820 5c71b47b62a3ddc8164fa9b57282337e 164 SMART SM00116 24 72 0.59 T 23-10-2018 IPR000644 CBS domain A3L01_02820 5c71b47b62a3ddc8164fa9b57282337e 164 SUPERFAMILY SSF54631 6 152 2.65E-21 T 23-10-2018 A3L01_02820 5c71b47b62a3ddc8164fa9b57282337e 164 Gene3D G3DSA:3.10.580.10 78 156 8.3E-13 T 23-10-2018 A3L01_07210 82277a992d227bb3232bfc2d1f92d947 140 PIRSF PIRSF006606 3 134 1.4E-44 T 23-10-2018 IPR007154 Protein of unknown function DUF356 A3L01_07210 82277a992d227bb3232bfc2d1f92d947 140 Pfam PF04009 Protein of unknown function (DUF356) 5 110 1.8E-34 T 23-10-2018 IPR007154 Protein of unknown function DUF356 A3L01_01485 f4d757092cd9c004d60fe2535a10d75d 441 PIRSF PIRSF001413 6 430 6.1E-156 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L01_01485 f4d757092cd9c004d60fe2535a10d75d 441 Gene3D G3DSA:3.40.50.1100 10 417 2.8E-176 T 23-10-2018 A3L01_01485 f4d757092cd9c004d60fe2535a10d75d 441 PIRSF PIRSF500824 1 433 1.1E-212 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L01_01485 f4d757092cd9c004d60fe2535a10d75d 441 Gene3D G3DSA:3.40.50.1100 11 236 2.8E-176 T 23-10-2018 A3L01_01485 f4d757092cd9c004d60fe2535a10d75d 441 SUPERFAMILY SSF53686 27 423 6.42E-111 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L01_01485 f4d757092cd9c004d60fe2535a10d75d 441 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 75 411 1.5E-45 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L01_01485 f4d757092cd9c004d60fe2535a10d75d 441 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 10 427 3.7E-218 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L01_01485 f4d757092cd9c004d60fe2535a10d75d 441 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 103 117 - T 23-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L01_01485 f4d757092cd9c004d60fe2535a10d75d 441 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 18 424 42.699 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L01_05475 a22503c13c711725ddd578fda90dc4cf 206 PIRSF PIRSF015877 1 199 9.0E-68 T 23-10-2018 IPR012041 Uncharacterised conserved protein UCP015877, zinc finger-containing A3L01_05475 a22503c13c711725ddd578fda90dc4cf 206 Pfam PF01873 Domain found in IF2B/IF5 2 34 5.2E-5 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L01_05475 a22503c13c711725ddd578fda90dc4cf 206 SUPERFAMILY SSF75689 4 38 3.27E-5 T 23-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L01_07080 acd25ca0ec5822d7976d8bca628be281 201 PIRSF PIRSF019239 29 201 8.5E-51 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L01_07080 acd25ca0ec5822d7976d8bca628be281 201 Pfam PF01899 Na+/H+ ion antiporter subunit 40 199 9.2E-41 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L01_04140 e08e21307905760f6f9102e01ce3ffca 122 SUPERFAMILY SSF103481 45 119 5.75E-11 T 23-10-2018 A3L01_04140 e08e21307905760f6f9102e01ce3ffca 122 Pfam PF00892 EamA-like transporter family 51 118 2.4E-8 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L01_00310 24b0e530e09bbbe0522329a5c3d13992 237 Gene3D G3DSA:3.40.50.300 7 235 1.5E-55 T 23-10-2018 A3L01_00310 24b0e530e09bbbe0522329a5c3d13992 237 SUPERFAMILY SSF52540 8 233 5.27E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_00310 24b0e530e09bbbe0522329a5c3d13992 237 Pfam PF06745 KaiC 13 234 3.7E-46 T 23-10-2018 IPR014774 KaiC-like domain A3L01_08995 9c2bafbba263adc2783bba36a2391092 325 Hamap MF_01446 tRNA N6-adenosine threonylcarbamoyltransferase [kae1]. 1 325 38.535 T 23-10-2018 IPR034680 tRNA N6-adenosine threonylcarbamoyltransferase Kae1/OSGEP GO:0000408|GO:0002949 Reactome: R-HSA-6782315 A3L01_08995 9c2bafbba263adc2783bba36a2391092 325 ProSitePatterns PS01016 Glycoprotease family signature. 92 112 - T 23-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 A3L01_08995 9c2bafbba263adc2783bba36a2391092 325 TIGRFAM TIGR03722 arch_KAE1: universal archaeal protein Kae1 4 324 1.3E-153 T 23-10-2018 IPR022449 tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea GO:0000408|GO:0002949 A3L01_08995 9c2bafbba263adc2783bba36a2391092 325 Gene3D G3DSA:3.30.420.40 4 298 4.4E-115 T 23-10-2018 A3L01_08995 9c2bafbba263adc2783bba36a2391092 325 Pfam PF00814 Glycoprotease family 22 292 6.2E-97 T 23-10-2018 IPR000905 Gcp-like domain A3L01_08995 9c2bafbba263adc2783bba36a2391092 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 93 112 2.4E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L01_08995 9c2bafbba263adc2783bba36a2391092 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 72 92 2.4E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L01_08995 9c2bafbba263adc2783bba36a2391092 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 124 136 2.4E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L01_08995 9c2bafbba263adc2783bba36a2391092 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 146 167 2.4E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L01_08995 9c2bafbba263adc2783bba36a2391092 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 2.4E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L01_08995 9c2bafbba263adc2783bba36a2391092 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 248 257 2.4E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L01_08995 9c2bafbba263adc2783bba36a2391092 325 Gene3D G3DSA:3.30.420.40 122 278 4.4E-115 T 23-10-2018 A3L01_08995 9c2bafbba263adc2783bba36a2391092 325 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 291 1.1E-100 T 23-10-2018 IPR017861 Kae1/TsaD family A3L01_08995 9c2bafbba263adc2783bba36a2391092 325 SUPERFAMILY SSF53067 1 293 2.41E-37 T 23-10-2018 A3L01_06990 3379d861e3f9fa59b0b1a874ba5e0c15 269 Pfam PF02535 ZIP Zinc transporter 121 264 3.7E-20 T 23-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 A3L01_04030 0e8f46c4632ad36775fe2a8a9ed9de94 120 Pfam PF09685 Domain of unknown function (DUF4870) 24 106 4.3E-11 T 23-10-2018 IPR019109 Protein of unknown function DUF4870 A3L01_06585 fd073fd896a3e95d7d9346f87418046f 345 SUPERFAMILY SSF53850 32 338 3.78E-50 T 23-10-2018 A3L01_06585 fd073fd896a3e95d7d9346f87418046f 345 Gene3D G3DSA:3.40.190.10 121 289 1.4E-127 T 23-10-2018 A3L01_06585 fd073fd896a3e95d7d9346f87418046f 345 Gene3D G3DSA:3.40.190.10 35 338 1.4E-127 T 23-10-2018 A3L01_06585 fd073fd896a3e95d7d9346f87418046f 345 TIGRFAM TIGR03730 tungstate_WtpA: tungstate ABC transporter binding protein WtpA 34 307 7.0E-120 T 23-10-2018 IPR022498 Tungstate ABC transporter, substrate-binding protein WtpA GO:1901359 A3L01_06585 fd073fd896a3e95d7d9346f87418046f 345 Pfam PF13531 Bacterial extracellular solute-binding protein 35 319 2.3E-34 T 23-10-2018 A3L01_06690 10b98973e215e9231342730324ea7fa1 283 SUPERFAMILY SSF161098 3 276 4.71E-47 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_06690 10b98973e215e9231342730324ea7fa1 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 270 2.2E-12 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_06690 10b98973e215e9231342730324ea7fa1 283 Gene3D G3DSA:1.10.3720.10 2 271 1.5E-45 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_03755 0384ea54847c821869f800a549e88bae 639 SUPERFAMILY SSF52540 422 626 1.18E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_03755 0384ea54847c821869f800a549e88bae 639 Pfam PF00583 Acetyltransferase (GNAT) family 275 339 2.2E-4 T 23-10-2018 IPR000182 GNAT domain A3L01_03755 0384ea54847c821869f800a549e88bae 639 Gene3D G3DSA:3.40.50.300 414 633 8.8E-38 T 23-10-2018 A3L01_03755 0384ea54847c821869f800a549e88bae 639 Pfam PF00005 ABC transporter 436 572 1.8E-18 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_03755 0384ea54847c821869f800a549e88bae 639 SMART SM00382 445 624 8.1E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_03755 0384ea54847c821869f800a549e88bae 639 SUPERFAMILY SSF55729 229 368 5.15E-9 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L01_03755 0384ea54847c821869f800a549e88bae 639 Gene3D G3DSA:3.40.630.30 220 349 3.9E-8 T 23-10-2018 A3L01_08960 f36390b97c45e561a1ab64e855430b4c 302 Pfam PF03168 Late embryogenesis abundant protein 187 266 4.1E-9 T 23-10-2018 IPR004864 Late embryogenesis abundant protein, LEA_2 subgroup A3L01_08960 f36390b97c45e561a1ab64e855430b4c 302 Gene3D G3DSA:2.60.40.10 30 145 2.2E-8 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_08960 f36390b97c45e561a1ab64e855430b4c 302 Gene3D G3DSA:2.60.40.10 164 295 3.7E-32 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_08960 f36390b97c45e561a1ab64e855430b4c 302 SUPERFAMILY SSF117070 160 266 2.75E-13 T 23-10-2018 A3L01_08960 f36390b97c45e561a1ab64e855430b4c 302 SMART SM00769 165 284 2.0E-8 T 23-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 A3L01_01760 6737fc45d97b196789d645cf54d636b0 993 SUPERFAMILY SSF69318 45 336 1.96E-27 T 23-10-2018 A3L01_01760 6737fc45d97b196789d645cf54d636b0 993 SUPERFAMILY SSF49299 751 841 5.62E-25 T 23-10-2018 IPR035986 PKD domain superfamily A3L01_01760 6737fc45d97b196789d645cf54d636b0 993 SUPERFAMILY SSF49299 843 927 4.19E-24 T 23-10-2018 IPR035986 PKD domain superfamily A3L01_01760 6737fc45d97b196789d645cf54d636b0 993 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 974 993 4.8E-6 T 23-10-2018 IPR027552 CGP-CTERM domain A3L01_01760 6737fc45d97b196789d645cf54d636b0 993 Pfam PF00801 PKD domain 858 916 6.3E-14 T 23-10-2018 IPR000601 PKD domain A3L01_01760 6737fc45d97b196789d645cf54d636b0 993 Pfam PF00801 PKD domain 676 742 2.8E-5 T 23-10-2018 IPR000601 PKD domain A3L01_01760 6737fc45d97b196789d645cf54d636b0 993 Pfam PF00801 PKD domain 764 829 1.0E-16 T 23-10-2018 IPR000601 PKD domain A3L01_01760 6737fc45d97b196789d645cf54d636b0 993 Gene3D G3DSA:2.60.40.10 753 840 3.8E-27 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_01760 6737fc45d97b196789d645cf54d636b0 993 SMART SM00089 847 929 6.0E-26 T 23-10-2018 IPR022409 PKD/Chitinase domain A3L01_01760 6737fc45d97b196789d645cf54d636b0 993 SMART SM00089 760 842 8.5E-25 T 23-10-2018 IPR022409 PKD/Chitinase domain A3L01_01760 6737fc45d97b196789d645cf54d636b0 993 SMART SM00089 672 756 9.3E-9 T 23-10-2018 IPR022409 PKD/Chitinase domain A3L01_01760 6737fc45d97b196789d645cf54d636b0 993 SUPERFAMILY SSF49299 668 755 5.23E-14 T 23-10-2018 IPR035986 PKD domain superfamily A3L01_01760 6737fc45d97b196789d645cf54d636b0 993 Gene3D G3DSA:2.120.10.30 66 310 2.9E-6 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A3L01_01760 6737fc45d97b196789d645cf54d636b0 993 Gene3D G3DSA:2.60.40.10 841 930 1.3E-26 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_01760 6737fc45d97b196789d645cf54d636b0 993 Gene3D G3DSA:2.60.40.10 666 752 6.9E-15 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_08605 cbf73461ba1628905573dfeae876c4d5 621 Pfam PF00326 Prolyl oligopeptidase family 397 605 1.0E-52 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A3L01_08605 cbf73461ba1628905573dfeae876c4d5 621 SUPERFAMILY SSF82171 23 352 5.3E-21 T 23-10-2018 A3L01_08605 cbf73461ba1628905573dfeae876c4d5 621 Gene3D G3DSA:2.120.10.30 22 143 5.4E-11 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A3L01_08605 cbf73461ba1628905573dfeae876c4d5 621 Gene3D G3DSA:3.40.50.1820 353 621 5.5E-82 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L01_08605 cbf73461ba1628905573dfeae876c4d5 621 SUPERFAMILY SSF53474 353 605 2.94E-57 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L01_01320 c447d1fc9353c210217db7957cb23aea 79 Gene3D G3DSA:3.30.70.920 1 74 2.4E-22 T 23-10-2018 A3L01_01320 c447d1fc9353c210217db7957cb23aea 79 SUPERFAMILY SSF54909 2 75 1.15E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L01_01320 c447d1fc9353c210217db7957cb23aea 79 Pfam PF01037 Lrp/AsnC ligand binding domain 6 74 5.9E-17 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L01_00990 ec257b4a5fb9c93c0e67127443e7338f 388 Gene3D G3DSA:1.20.1250.20 207 382 4.7E-8 T 23-10-2018 A3L01_00990 ec257b4a5fb9c93c0e67127443e7338f 388 Gene3D G3DSA:1.20.1250.20 1 198 1.7E-13 T 23-10-2018 A3L01_00990 ec257b4a5fb9c93c0e67127443e7338f 388 Pfam PF07690 Major Facilitator Superfamily 12 343 8.7E-19 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L01_00990 ec257b4a5fb9c93c0e67127443e7338f 388 SUPERFAMILY SSF103473 8 379 1.83E-26 T 23-10-2018 IPR036259 MFS transporter superfamily A3L01_01690 53184071eb13641be07a0001e653eb1d 194 Gene3D G3DSA:3.90.550.10 4 192 2.3E-40 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_01690 53184071eb13641be07a0001e653eb1d 194 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 188 19.307 T 23-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 A3L01_01690 53184071eb13641be07a0001e653eb1d 194 SUPERFAMILY SSF53448 1 185 7.21E-28 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_01690 53184071eb13641be07a0001e653eb1d 194 Pfam PF12804 MobA-like NTP transferase domain 3 134 1.0E-28 T 23-10-2018 IPR025877 MobA-like NTP transferase A3L01_06380 72160b67e29355428dbe93da284b9442 518 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 84 106 - T 23-10-2018 IPR023765 Solute-binding protein family 5, conserved site A3L01_06380 72160b67e29355428dbe93da284b9442 518 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 438 8.7E-105 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain A3L01_06380 72160b67e29355428dbe93da284b9442 518 Gene3D G3DSA:3.10.105.10 275 494 3.9E-145 T 23-10-2018 A3L01_06380 72160b67e29355428dbe93da284b9442 518 Gene3D G3DSA:3.40.190.10 193 505 3.9E-145 T 23-10-2018 A3L01_06380 72160b67e29355428dbe93da284b9442 518 SUPERFAMILY SSF53850 33 517 1.97E-145 T 23-10-2018 A3L01_06380 72160b67e29355428dbe93da284b9442 518 Gene3D G3DSA:3.90.76.10 50 192 3.9E-145 T 23-10-2018 A3L01_06380 72160b67e29355428dbe93da284b9442 518 PIRSF PIRSF002741 4 516 5.0E-113 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A3L01_01535 76e65ef6777122849baddfd29a3f9297 419 SUPERFAMILY SSF51735 182 417 3.8E-82 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_01535 76e65ef6777122849baddfd29a3f9297 419 SMART SM00839 184 415 3.3E-99 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L01_01535 76e65ef6777122849baddfd29a3f9297 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 173 195 7.1E-30 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L01_01535 76e65ef6777122849baddfd29a3f9297 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 343 354 7.1E-30 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L01_01535 76e65ef6777122849baddfd29a3f9297 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 91 105 7.1E-30 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L01_01535 76e65ef6777122849baddfd29a3f9297 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 215 235 7.1E-30 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L01_01535 76e65ef6777122849baddfd29a3f9297 419 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 182 415 3.8E-76 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L01_01535 76e65ef6777122849baddfd29a3f9297 419 Gene3D G3DSA:3.40.50.720 182 418 4.7E-97 T 23-10-2018 A3L01_01535 76e65ef6777122849baddfd29a3f9297 419 SUPERFAMILY SSF53223 4 184 3.52E-66 T 23-10-2018 A3L01_01535 76e65ef6777122849baddfd29a3f9297 419 Gene3D G3DSA:3.40.50.10860 36 180 1.3E-65 T 23-10-2018 A3L01_01535 76e65ef6777122849baddfd29a3f9297 419 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 99 112 - T 23-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L01_01535 76e65ef6777122849baddfd29a3f9297 419 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 34 161 6.1E-53 T 23-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L01_01535 76e65ef6777122849baddfd29a3f9297 419 PIRSF PIRSF000185 1 418 6.7E-173 T 23-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 A3L01_01590 741cda8a602f28a2622f25f00905f4c2 463 Pfam PF01554 MatE 27 186 1.4E-33 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L01_01590 741cda8a602f28a2622f25f00905f4c2 463 Pfam PF01554 MatE 264 418 2.2E-24 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L01_01590 741cda8a602f28a2622f25f00905f4c2 463 PIRSF PIRSF006603 2 463 2.5E-143 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L01_01590 741cda8a602f28a2622f25f00905f4c2 463 TIGRFAM TIGR00797 matE: MATE efflux family protein 27 429 3.9E-74 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L01_09020 1e94da1cd3ea6bf9ec08cf197183ee35 226 Pfam PF05690 Thiazole biosynthesis protein ThiG 167 216 6.2E-6 T 23-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A3L01_09020 1e94da1cd3ea6bf9ec08cf197183ee35 226 Pfam PF00121 Triosephosphate isomerase 8 112 1.0E-9 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_09020 1e94da1cd3ea6bf9ec08cf197183ee35 226 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 8 212 1.0E-61 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_09020 1e94da1cd3ea6bf9ec08cf197183ee35 226 Gene3D G3DSA:3.20.20.70 1 225 8.2E-94 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_09020 1e94da1cd3ea6bf9ec08cf197183ee35 226 SUPERFAMILY SSF51351 4 223 1.57E-46 T 23-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_09020 1e94da1cd3ea6bf9ec08cf197183ee35 226 Hamap MF_00147_A Triosephosphate isomerase [tpiA]. 6 225 43.943 T 23-10-2018 IPR022891 Triosephosphate isomerase, archaeal GO:0004807|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003 A3L01_09020 1e94da1cd3ea6bf9ec08cf197183ee35 226 ProSitePatterns PS00171 Triosephosphate isomerase active site. 142 152 - T 23-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_08515 98338c803244f569cfce8e00350fb25c 175 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 8 175 2.6E-62 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 A3L01_08515 98338c803244f569cfce8e00350fb25c 175 Gene3D G3DSA:3.40.50.300 2 175 1.0E-65 T 23-10-2018 A3L01_08515 98338c803244f569cfce8e00350fb25c 175 PIRSF PIRSF015617 1 175 1.0E-63 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 A3L01_08515 98338c803244f569cfce8e00350fb25c 175 SUPERFAMILY SSF52540 4 175 1.8E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_08515 98338c803244f569cfce8e00350fb25c 175 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 3 175 3.0E-70 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 A3L01_09720 099e787036c9d24f760b77802203d770 913 SUPERFAMILY SSF55186 603 752 8.37E-48 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A3L01_09720 099e787036c9d24f760b77802203d770 913 Gene3D G3DSA:2.40.30.130 502 599 1.1E-36 T 23-10-2018 A3L01_09720 099e787036c9d24f760b77802203d770 913 Gene3D G3DSA:3.10.310.40 813 913 1.4E-20 T 23-10-2018 A3L01_09720 099e787036c9d24f760b77802203d770 913 SUPERFAMILY SSF101353 306 520 7.85E-51 T 23-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A3L01_09720 099e787036c9d24f760b77802203d770 913 Pfam PF02272 DHHA1 domain 782 910 7.2E-19 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L01_09720 099e787036c9d24f760b77802203d770 913 Gene3D G3DSA:3.30.980.10 605 674 1.0E-21 T 23-10-2018 A3L01_09720 099e787036c9d24f760b77802203d770 913 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 61 893 2.3E-234 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L01_09720 099e787036c9d24f760b77802203d770 913 SUPERFAMILY SSF50447 512 597 3.14E-19 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L01_09720 099e787036c9d24f760b77802203d770 913 Gene3D G3DSA:3.30.54.20 675 726 8.6E-29 T 23-10-2018 A3L01_09720 099e787036c9d24f760b77802203d770 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 336 352 4.6E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L01_09720 099e787036c9d24f760b77802203d770 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 127 138 4.6E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L01_09720 099e787036c9d24f760b77802203d770 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 360 373 4.6E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L01_09720 099e787036c9d24f760b77802203d770 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 245 258 4.6E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L01_09720 099e787036c9d24f760b77802203d770 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 206 217 4.6E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L01_09720 099e787036c9d24f760b77802203d770 913 Gene3D G3DSA:3.30.930.10 1 260 5.4E-114 T 23-10-2018 A3L01_09720 099e787036c9d24f760b77802203d770 913 TIGRFAM TIGR03683 A-tRNA_syn_arch: alanine--tRNA ligase 4 911 0.0 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A3L01_09720 099e787036c9d24f760b77802203d770 913 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 702 744 1.2E-14 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L01_09720 099e787036c9d24f760b77802203d770 913 SUPERFAMILY SSF55681 57 264 1.21E-57 T 23-10-2018 A3L01_09720 099e787036c9d24f760b77802203d770 913 Pfam PF01411 tRNA synthetases class II (A) 61 603 1.3E-161 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A3L01_09720 099e787036c9d24f760b77802203d770 913 SMART SM00863 702 745 2.2E-17 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L01_09720 099e787036c9d24f760b77802203d770 913 Hamap MF_00036_A Alanine--tRNA ligase [alaS]. 4 910 24.16 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A3L01_05980 e32f813c929cc660c6ee13696d8d8f0b 255 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 245 47.916 T 23-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A3L01_05980 e32f813c929cc660c6ee13696d8d8f0b 255 Pfam PF03746 LamB/YcsF family 3 241 9.4E-106 T 23-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A3L01_05980 e32f813c929cc660c6ee13696d8d8f0b 255 Gene3D G3DSA:3.20.20.370 1 255 7.2E-112 T 23-10-2018 A3L01_05980 e32f813c929cc660c6ee13696d8d8f0b 255 SUPERFAMILY SSF88713 1 252 1.72E-105 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L01_03650 d64129a1bf736a6e58d1a5e5ef7a63be 170 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 9 166 9.2E-38 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L01_03650 d64129a1bf736a6e58d1a5e5ef7a63be 170 SUPERFAMILY SSF53323 2 167 4.97E-42 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L01_03650 d64129a1bf736a6e58d1a5e5ef7a63be 170 Gene3D G3DSA:3.40.920.10 1 169 5.1E-54 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L01_04685 ef11e9e8eb3fb2767fcb6f86fe598094 93 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 3 92 3.2E-28 T 23-10-2018 IPR002767 Thiamine-binding protein A3L01_04685 ef11e9e8eb3fb2767fcb6f86fe598094 93 Pfam PF01910 Thiamine-binding protein 4 92 1.8E-30 T 23-10-2018 IPR002767 Thiamine-binding protein A3L01_04685 ef11e9e8eb3fb2767fcb6f86fe598094 93 SUPERFAMILY SSF89957 1 92 2.62E-29 T 23-10-2018 IPR029756 MTH1187/YkoF-like A3L01_04685 ef11e9e8eb3fb2767fcb6f86fe598094 93 Gene3D G3DSA:3.30.70.930 1 93 2.7E-33 T 23-10-2018 IPR029756 MTH1187/YkoF-like A3L01_07435 060855a9eb709d027af66568b6a787c1 508 Gene3D G3DSA:1.10.287.70 393 508 8.2E-14 T 23-10-2018 A3L01_07435 060855a9eb709d027af66568b6a787c1 508 SUPERFAMILY SSF81324 383 507 1.22E-14 T 23-10-2018 A3L01_07435 060855a9eb709d027af66568b6a787c1 508 SUPERFAMILY SSF141571 31 171 3.79E-7 T 23-10-2018 A3L01_07435 060855a9eb709d027af66568b6a787c1 508 Pfam PF00805 Pentapeptide repeats (8 copies) 65 94 0.002 T 23-10-2018 IPR001646 Pentapeptide repeat A3L01_07435 060855a9eb709d027af66568b6a787c1 508 Pfam PF13576 Pentapeptide repeats (9 copies) 164 208 3.0E-8 T 23-10-2018 IPR001646 Pentapeptide repeat A3L01_07435 060855a9eb709d027af66568b6a787c1 508 Pfam PF13576 Pentapeptide repeats (9 copies) 4 49 6.2E-10 T 23-10-2018 IPR001646 Pentapeptide repeat A3L01_07435 060855a9eb709d027af66568b6a787c1 508 Pfam PF07885 Ion channel 454 505 2.0E-12 T 23-10-2018 IPR013099 Potassium channel domain A3L01_07435 060855a9eb709d027af66568b6a787c1 508 Gene3D G3DSA:2.160.20.100 4 114 1.3E-9 T 23-10-2018 A3L01_04085 b0b34a2f2295cb8b88c494af878e2b01 274 Pfam PF00753 Metallo-beta-lactamase superfamily 22 101 3.3E-14 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_04085 b0b34a2f2295cb8b88c494af878e2b01 274 SMART SM00849 21 245 1.3E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_04085 b0b34a2f2295cb8b88c494af878e2b01 274 Gene3D G3DSA:3.60.15.10 1 274 5.6E-88 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_04085 b0b34a2f2295cb8b88c494af878e2b01 274 SUPERFAMILY SSF56281 5 274 2.62E-37 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_06090 4f38bd327504b363eb9698494413a3c6 134 Pfam PF05168 HEPN domain 8 128 1.8E-34 T 23-10-2018 IPR007842 HEPN domain A3L01_06090 4f38bd327504b363eb9698494413a3c6 134 Gene3D G3DSA:1.20.120.330 3 130 3.6E-39 T 23-10-2018 A3L01_06090 4f38bd327504b363eb9698494413a3c6 134 SMART SM00748 11 122 8.7E-41 T 23-10-2018 IPR007842 HEPN domain A3L01_06090 4f38bd327504b363eb9698494413a3c6 134 SUPERFAMILY SSF81593 5 128 1.57E-43 T 23-10-2018 A3L01_03240 b53a83b799dc76c1a8ae932b95561cd9 377 Pfam PF04007 Protein of unknown function (DUF354) 1 320 1.7E-97 T 23-10-2018 IPR007152 Protein of unknown function DUF354 A3L01_03240 b53a83b799dc76c1a8ae932b95561cd9 377 SUPERFAMILY SSF53756 1 319 1.75E-25 T 23-10-2018 A3L01_03240 b53a83b799dc76c1a8ae932b95561cd9 377 PIRSF PIRSF005357 1 346 4.8E-117 T 23-10-2018 IPR007152 Protein of unknown function DUF354 A3L01_01435 e4d3bcd0ab09a2ee5aa5234a72399de6 967 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 6 967 18.36 T 23-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 A3L01_01435 e4d3bcd0ab09a2ee5aa5234a72399de6 967 Gene3D G3DSA:1.10.730.10 690 810 2.9E-35 T 23-10-2018 A3L01_01435 e4d3bcd0ab09a2ee5aa5234a72399de6 967 Gene3D G3DSA:3.30.2320.20 835 967 1.5E-47 T 23-10-2018 A3L01_01435 e4d3bcd0ab09a2ee5aa5234a72399de6 967 Gene3D G3DSA:1.10.10.720 866 917 1.5E-47 T 23-10-2018 A3L01_01435 e4d3bcd0ab09a2ee5aa5234a72399de6 967 SUPERFAMILY SSF47323 713 903 2.62E-38 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_01435 e4d3bcd0ab09a2ee5aa5234a72399de6 967 Gene3D G3DSA:3.40.50.620 9 688 4.8E-302 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_01435 e4d3bcd0ab09a2ee5aa5234a72399de6 967 Gene3D G3DSA:3.90.740.10 205 451 4.8E-302 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L01_01435 e4d3bcd0ab09a2ee5aa5234a72399de6 967 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_01435 e4d3bcd0ab09a2ee5aa5234a72399de6 967 SUPERFAMILY SSF52374 4 694 1.05E-100 T 23-10-2018 A3L01_01435 e4d3bcd0ab09a2ee5aa5234a72399de6 967 Pfam PF08264 Anticodon-binding domain of tRNA 726 857 6.1E-31 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A3L01_01435 e4d3bcd0ab09a2ee5aa5234a72399de6 967 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 12 689 5.5E-68 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_01435 e4d3bcd0ab09a2ee5aa5234a72399de6 967 SUPERFAMILY SSF50677 210 443 2.44E-33 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L01_01435 e4d3bcd0ab09a2ee5aa5234a72399de6 967 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 8 967 0.0 T 23-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L01_05300 59ac76bae739d67247542f288f61a236 140 Pfam PF03479 Domain of unknown function (DUF296) 8 117 2.4E-18 T 23-10-2018 IPR005175 PPC domain A3L01_05300 59ac76bae739d67247542f288f61a236 140 Gene3D G3DSA:3.30.1330.80 1 140 5.2E-48 T 23-10-2018 A3L01_05300 59ac76bae739d67247542f288f61a236 140 PIRSF PIRSF016702 1 139 2.4E-43 T 23-10-2018 IPR025707 Predicted DNA-binding protein with PD1-like DNA-binding motif A3L01_05300 59ac76bae739d67247542f288f61a236 140 SUPERFAMILY SSF117856 4 129 1.57E-35 T 23-10-2018 A3L01_07900 bce08d48e34a7cd245ce7bddaae22b88 448 Gene3D G3DSA:3.40.50.720 3 132 3.3E-8 T 23-10-2018 A3L01_07900 bce08d48e34a7cd245ce7bddaae22b88 448 Gene3D G3DSA:3.40.50.300 211 304 1.5E-7 T 23-10-2018 A3L01_07900 bce08d48e34a7cd245ce7bddaae22b88 448 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 241 299 4.2E-5 T 23-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain A3L01_07900 bce08d48e34a7cd245ce7bddaae22b88 448 SUPERFAMILY SSF52540 125 295 6.91E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_02895 25fe7faed7a1f39aa88225a5752f23e4 249 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 5 219 30.704 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A3L01_02895 25fe7faed7a1f39aa88225a5752f23e4 249 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 7 199 1.7E-51 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A3L01_02895 25fe7faed7a1f39aa88225a5752f23e4 249 SUPERFAMILY SSF69796 4 198 1.57E-59 T 23-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A3L01_02895 25fe7faed7a1f39aa88225a5752f23e4 249 Gene3D G3DSA:3.30.1360.170 1 203 4.1E-63 T 23-10-2018 A3L01_02895 25fe7faed7a1f39aa88225a5752f23e4 249 Pfam PF02511 Thymidylate synthase complementing protein 8 198 2.8E-62 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A3L01_05535 736061ff514cdc8b9bbbcd7680ca1474 169 Pfam PF01917 Archaebacterial flagellin 8 139 2.7E-7 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 A3L01_05795 8f2c3711d2cb6c276aadbef5e7a07b4d 255 SUPERFAMILY SSF51658 16 253 2.49E-49 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily A3L01_05795 8f2c3711d2cb6c276aadbef5e7a07b4d 255 Pfam PF01261 Xylose isomerase-like TIM barrel 22 220 5.1E-34 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A3L01_05795 8f2c3711d2cb6c276aadbef5e7a07b4d 255 Gene3D G3DSA:3.20.20.150 1 255 3.4E-60 T 23-10-2018 A3L01_05795 8f2c3711d2cb6c276aadbef5e7a07b4d 255 SMART SM00518 1 255 0.0034 T 23-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A3L01_00665 246b6e75dbce10aa6385453d7c738d5d 392 Pfam PF07690 Major Facilitator Superfamily 214 387 4.1E-14 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L01_00665 246b6e75dbce10aa6385453d7c738d5d 392 Pfam PF07690 Major Facilitator Superfamily 20 189 2.5E-20 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L01_00665 246b6e75dbce10aa6385453d7c738d5d 392 SUPERFAMILY SSF103473 11 384 5.1E-53 T 23-10-2018 IPR036259 MFS transporter superfamily A3L01_00665 246b6e75dbce10aa6385453d7c738d5d 392 Gene3D G3DSA:1.20.1250.20 8 211 1.0E-27 T 23-10-2018 A3L01_00665 246b6e75dbce10aa6385453d7c738d5d 392 Gene3D G3DSA:1.20.1250.20 212 386 4.2E-19 T 23-10-2018 A3L01_08100 d2f5f0de1f66a5c722594c01da4fbfa1 171 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 12 171 1.3E-60 T 23-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A3L01_08100 d2f5f0de1f66a5c722594c01da4fbfa1 171 Pfam PF05683 Fumarase C-terminus 3 170 1.3E-43 T 23-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A3L01_08100 d2f5f0de1f66a5c722594c01da4fbfa1 171 SUPERFAMILY SSF117457 4 170 6.28E-56 T 23-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 A3L01_08100 d2f5f0de1f66a5c722594c01da4fbfa1 171 Gene3D G3DSA:3.20.130.10 1 171 2.6E-70 T 23-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 A3L01_03220 b4f2d404c3b3680583a036ea2092fa30 419 SMART SM00729 115 333 4.7E-14 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L01_03220 b4f2d404c3b3680583a036ea2092fa30 419 Pfam PF04055 Radical SAM superfamily 123 287 6.6E-28 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L01_03220 b4f2d404c3b3680583a036ea2092fa30 419 SUPERFAMILY SSF102114 111 333 4.58E-39 T 23-10-2018 A3L01_03220 b4f2d404c3b3680583a036ea2092fa30 419 Gene3D G3DSA:3.20.20.70 113 358 1.3E-38 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_03105 f34989402552630b5470769837f050eb 128 Pfam PF01022 Bacterial regulatory protein, arsR family 17 51 5.3E-6 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_03105 f34989402552630b5470769837f050eb 128 SUPERFAMILY SSF47413 14 53 2.31E-6 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L01_03105 f34989402552630b5470769837f050eb 128 Gene3D G3DSA:1.10.260.40 16 61 7.5E-7 T 23-10-2018 A3L01_05555 7189b0ec07db10f578ffaac6eaf1d5a7 320 SUPERFAMILY SSF53335 127 302 3.5E-30 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_05555 7189b0ec07db10f578ffaac6eaf1d5a7 320 Gene3D G3DSA:3.40.50.150 113 314 1.3E-29 T 23-10-2018 A3L01_05555 7189b0ec07db10f578ffaac6eaf1d5a7 320 Pfam PF13847 Methyltransferase domain 157 264 1.1E-16 T 23-10-2018 IPR025714 Methyltransferase domain A3L01_04490 80fd451622d9a49df0c7f14a639f8f9b 291 Pfam PF00753 Metallo-beta-lactamase superfamily 16 189 1.4E-11 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_04490 80fd451622d9a49df0c7f14a639f8f9b 291 SUPERFAMILY SSF56281 4 277 9.66E-37 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_04490 80fd451622d9a49df0c7f14a639f8f9b 291 Gene3D G3DSA:3.60.15.10 1 223 1.7E-28 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_04490 80fd451622d9a49df0c7f14a639f8f9b 291 SMART SM00849 15 200 3.2E-15 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_09710 c8ad4facc30b1328cc75f894329a4bd8 309 Gene3D G3DSA:2.10.109.10 25 136 3.7E-7 T 23-10-2018 A3L01_09710 c8ad4facc30b1328cc75f894329a4bd8 309 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 7 150 1.0E-30 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L01_09710 c8ad4facc30b1328cc75f894329a4bd8 309 SUPERFAMILY SSF51306 27 128 4.71E-13 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A3L01_09710 c8ad4facc30b1328cc75f894329a4bd8 309 Pfam PF00717 Peptidase S24-like 30 81 1.3E-7 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A3L01_09710 c8ad4facc30b1328cc75f894329a4bd8 309 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 30 45 2.7E-7 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L01_09710 c8ad4facc30b1328cc75f894329a4bd8 309 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 91 102 2.7E-7 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L01_01825 1dfb992a5c47070ec70f468900fcbe0e 219 Pfam PF02361 Cobalt transport protein 23 193 1.1E-24 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component A3L01_06325 3ca328f511d436c2ea73b82c78800be0 285 Gene3D G3DSA:3.60.15.10 50 127 2.5E-22 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_06325 3ca328f511d436c2ea73b82c78800be0 285 Gene3D G3DSA:3.40.50.10890 128 172 2.5E-22 T 23-10-2018 A3L01_06325 3ca328f511d436c2ea73b82c78800be0 285 SUPERFAMILY SSF56281 14 280 1.08E-40 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_02310 016bd40698c8d820314f18106989e808 315 TIGRFAM TIGR02583 DevR_archaea: CRISPR-associated protein Cas7/Csa2, subtype I-A/APERN 2 282 8.8E-106 T 23-10-2018 IPR002764 CRISPR-associated protein Cas7/Cst2/DevR, subtype I-a/Apern A3L01_02310 016bd40698c8d820314f18106989e808 315 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 5 273 4.2E-81 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR A3L01_02310 016bd40698c8d820314f18106989e808 315 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 4 258 6.1E-45 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR A3L01_03510 0cd4ca08c3eb9aceabfc5a6f99343d9c 189 Gene3D G3DSA:3.30.2170.10 144 187 1.7E-7 T 23-10-2018 A3L01_03510 0cd4ca08c3eb9aceabfc5a6f99343d9c 189 Pfam PF04493 Endonuclease V 144 182 3.0E-5 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 A3L01_03510 0cd4ca08c3eb9aceabfc5a6f99343d9c 189 Pfam PF04493 Endonuclease V 16 139 3.8E-33 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 A3L01_03510 0cd4ca08c3eb9aceabfc5a6f99343d9c 189 Hamap MF_00801 Endonuclease V [nfi]. 6 189 26.092 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 A3L01_03510 0cd4ca08c3eb9aceabfc5a6f99343d9c 189 Gene3D G3DSA:3.30.2170.10 1 143 3.6E-37 T 23-10-2018 A3L01_05045 c9c888eba71921aacacc592b00c28ee0 126 Pfam PF00174 Oxidoreductase molybdopterin binding domain 16 107 1.4E-17 T 23-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 A3L01_05045 c9c888eba71921aacacc592b00c28ee0 126 SUPERFAMILY SSF56524 3 116 7.46E-29 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 A3L01_05045 c9c888eba71921aacacc592b00c28ee0 126 Gene3D G3DSA:3.90.420.10 9 123 3.5E-22 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 A3L01_05425 1554cfcf0eb48fd72531bbbe3b392399 237 Pfam PF01904 Protein of unknown function DUF72 14 234 5.5E-37 T 23-10-2018 IPR002763 Protein of unknown function DUF72 A3L01_05425 1554cfcf0eb48fd72531bbbe3b392399 237 Gene3D G3DSA:3.20.20.410 1 237 8.1E-41 T 23-10-2018 IPR036520 UPF0759 superfamily A3L01_05425 1554cfcf0eb48fd72531bbbe3b392399 237 SUPERFAMILY SSF117396 2 237 4.71E-46 T 23-10-2018 IPR036520 UPF0759 superfamily A3L01_05350 6fe04e7f16f0084bdd28fe27bde0bf24 356 Pfam PF01008 Initiation factor 2 subunit family 55 343 2.2E-81 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A3L01_05350 6fe04e7f16f0084bdd28fe27bde0bf24 356 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 42 343 4.3E-113 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L01_05350 6fe04e7f16f0084bdd28fe27bde0bf24 356 Gene3D G3DSA:1.20.120.420 11 156 2.0E-46 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L01_05350 6fe04e7f16f0084bdd28fe27bde0bf24 356 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 15 342 2.1E-127 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L01_05350 6fe04e7f16f0084bdd28fe27bde0bf24 356 Gene3D G3DSA:3.40.50.10470 159 356 1.4E-59 T 23-10-2018 A3L01_05350 6fe04e7f16f0084bdd28fe27bde0bf24 356 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 13 353 39.918 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L01_05350 6fe04e7f16f0084bdd28fe27bde0bf24 356 SUPERFAMILY SSF100950 12 350 1.53E-114 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L01_02795 21081d580d1f8b400b55aff0ca60bb30 327 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 2 151 1.8E-27 T 23-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A3L01_02795 21081d580d1f8b400b55aff0ca60bb30 327 PIRSF PIRSF000808 1 314 6.7E-106 T 23-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A3L01_02795 21081d580d1f8b400b55aff0ca60bb30 327 Gene3D G3DSA:3.30.428.10 3 309 9.9E-92 T 23-10-2018 IPR036265 HIT-like superfamily A3L01_02795 21081d580d1f8b400b55aff0ca60bb30 327 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 159 311 8.5E-13 T 23-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A3L01_02795 21081d580d1f8b400b55aff0ca60bb30 327 SUPERFAMILY SSF54197 154 317 9.74E-41 T 23-10-2018 IPR036265 HIT-like superfamily A3L01_02795 21081d580d1f8b400b55aff0ca60bb30 327 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 5 310 8.2E-51 T 23-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A3L01_02795 21081d580d1f8b400b55aff0ca60bb30 327 SUPERFAMILY SSF54197 1 151 1.29E-47 T 23-10-2018 IPR036265 HIT-like superfamily A3L01_02795 21081d580d1f8b400b55aff0ca60bb30 327 Gene3D G3DSA:3.30.428.10 31 150 9.9E-92 T 23-10-2018 IPR036265 HIT-like superfamily A3L01_05545 816e5d802b23b12ca9968dd6d1c67337 170 Pfam PF05377 Flagella accessory protein C (FlaC) 60 113 1.1E-19 T 23-10-2018 IPR009205 Predicted archaeal flagellar protein C A3L01_05545 816e5d802b23b12ca9968dd6d1c67337 170 Gene3D G3DSA:1.20.5.340 18 150 6.9E-7 T 23-10-2018 A3L01_01175 11c4930001ab51f325b0026f29e651c6 83 Gene3D G3DSA:2.30.30.30 2 83 1.0E-28 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L01_01175 11c4930001ab51f325b0026f29e651c6 83 SUPERFAMILY SSF50104 2 80 1.2E-18 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L01_01175 11c4930001ab51f325b0026f29e651c6 83 Pfam PF01929 Ribosomal protein L14 44 81 2.3E-4 T 23-10-2018 IPR002784 Ribosomal protein L14e domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01175 11c4930001ab51f325b0026f29e651c6 83 Hamap MF_00721 50S ribosomal protein L14e [rpl14e]. 1 79 26.155 T 23-10-2018 IPR023651 Ribosomal protein L14e GO:0003735|GO:0005840|GO:0006412 A3L01_02905 21022d50295522874055890045646755 168 SUPERFAMILY SSF54197 1 155 1.15E-46 T 23-10-2018 IPR036265 HIT-like superfamily A3L01_02905 21022d50295522874055890045646755 168 Gene3D G3DSA:3.30.428.10 1 165 1.2E-58 T 23-10-2018 IPR036265 HIT-like superfamily A3L01_02905 21022d50295522874055890045646755 168 Pfam PF01230 HIT domain 35 125 1.0E-14 T 23-10-2018 IPR001310 Histidine triad (HIT) protein A3L01_06355 6aac90d7434ee76580351f1497f45d7b 244 SUPERFAMILY SSF52540 1 111 1.66E-11 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06355 6aac90d7434ee76580351f1497f45d7b 244 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 111 3.8E-18 T 23-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A3L01_06355 6aac90d7434ee76580351f1497f45d7b 244 Gene3D G3DSA:3.20.20.20 158 219 6.4E-6 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L01_06355 6aac90d7434ee76580351f1497f45d7b 244 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 5 122 1.2E-22 T 23-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A3L01_06355 6aac90d7434ee76580351f1497f45d7b 244 Pfam PF04060 Putative Fe-S cluster 160 191 6.8E-9 T 23-10-2018 IPR007202 4Fe-4S domain GO:0051536 A3L01_06355 6aac90d7434ee76580351f1497f45d7b 244 Gene3D G3DSA:3.40.50.300 1 157 7.1E-29 T 23-10-2018 A3L01_05275 ffd34d2f7c1f2eaff6baa782fe91ce47 203 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 107 5.1E-22 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A3L01_05275 ffd34d2f7c1f2eaff6baa782fe91ce47 203 SUPERFAMILY SSF53146 1 118 9.81E-29 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L01_05275 ffd34d2f7c1f2eaff6baa782fe91ce47 203 Gene3D G3DSA:3.30.420.130 1 118 1.7E-28 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L01_08785 86ce92fcd0d9f5a04bfa95d0deb8c7e8 148 Gene3D G3DSA:3.40.50.12280 1 148 5.3E-57 T 23-10-2018 A3L01_08785 86ce92fcd0d9f5a04bfa95d0deb8c7e8 148 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 7 134 3.7E-44 T 23-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_08785 86ce92fcd0d9f5a04bfa95d0deb8c7e8 148 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 21 131 8.3E-29 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_08785 86ce92fcd0d9f5a04bfa95d0deb8c7e8 148 SUPERFAMILY SSF56770 7 137 9.42E-56 T 23-10-2018 A3L01_07215 9988054c8f0ec6aa95cf67016f0189e4 179 Pfam PF01381 Helix-turn-helix 95 143 7.7E-7 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L01_07215 9988054c8f0ec6aa95cf67016f0189e4 179 SMART SM00530 91 146 8.2E-6 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L01_07215 9988054c8f0ec6aa95cf67016f0189e4 179 TIGRFAM TIGR00270 TIGR00270: TIGR00270 family protein 8 172 1.1E-22 T 23-10-2018 IPR004451 Conserved hypothetical protein CHP00270 A3L01_07215 9988054c8f0ec6aa95cf67016f0189e4 179 Gene3D G3DSA:1.10.260.40 80 179 8.5E-11 T 23-10-2018 A3L01_07215 9988054c8f0ec6aa95cf67016f0189e4 179 SUPERFAMILY SSF47413 81 145 5.09E-7 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L01_06410 9030b9d95e08c5de273ed253e2b85b3c 249 SUPERFAMILY SSF56281 3 247 1.44E-41 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_06410 9030b9d95e08c5de273ed253e2b85b3c 249 SMART SM00849 37 215 9.3E-17 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_06410 9030b9d95e08c5de273ed253e2b85b3c 249 Pfam PF12706 Beta-lactamase superfamily domain 64 216 7.1E-18 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_06410 9030b9d95e08c5de273ed253e2b85b3c 249 Gene3D G3DSA:3.60.15.10 2 249 4.0E-50 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_06125 adbd3d1eaae96e80a34883a39197b1b8 184 Hamap MF_00528 Septum formation protein Maf [maf]. 1 183 30.275 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A3L01_06125 adbd3d1eaae96e80a34883a39197b1b8 184 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 175 4.4E-49 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A3L01_06125 adbd3d1eaae96e80a34883a39197b1b8 184 SUPERFAMILY SSF52972 1 175 3.92E-57 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L01_06125 adbd3d1eaae96e80a34883a39197b1b8 184 Gene3D G3DSA:3.90.950.10 1 180 1.9E-64 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L01_06125 adbd3d1eaae96e80a34883a39197b1b8 184 PIRSF PIRSF006305 1 183 3.4E-58 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A3L01_06125 adbd3d1eaae96e80a34883a39197b1b8 184 Pfam PF02545 Maf-like protein 2 175 3.5E-57 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A3L01_03275 d0c0f050228f6a218edaa9404cd06e7a 78 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 9 77 5.3E-7 T 23-10-2018 IPR010001 SigmaK-factor processing regulatory BofA A3L01_02355 0c648a52bf25306cbe05103de6e8d30b 70 Pfam PF01022 Bacterial regulatory protein, arsR family 4 44 8.5E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_02355 0c648a52bf25306cbe05103de6e8d30b 70 Gene3D G3DSA:1.10.10.10 1 70 2.2E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_02355 0c648a52bf25306cbe05103de6e8d30b 70 SUPERFAMILY SSF46785 4 61 1.49E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_00640 3169e2c4722a89073072ce02019b7c9a 130 Pfam PF01850 PIN domain 2 120 2.2E-8 T 23-10-2018 IPR002716 PIN domain A3L01_00640 3169e2c4722a89073072ce02019b7c9a 130 SUPERFAMILY SSF88723 2 123 1.96E-15 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L01_00640 3169e2c4722a89073072ce02019b7c9a 130 Gene3D G3DSA:3.40.50.1010 1 125 1.8E-28 T 23-10-2018 A3L01_00855 40462fc59d110b30b642bca375cbe171 123 PIRSF PIRSF018867 1 120 3.1E-30 T 23-10-2018 IPR014497 Methylmalonyl-CoA decarboxylase, delta subunit A3L01_00855 40462fc59d110b30b642bca375cbe171 123 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 4 82 2.6E-13 T 23-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 A3L01_00855 40462fc59d110b30b642bca375cbe171 123 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 6 80 2.2E-14 T 23-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 A3L01_01540 f3d4fb39cdb4589ecab12a99eebdcaab 116 SUPERFAMILY SSF81324 14 113 4.97E-17 T 23-10-2018 A3L01_01540 f3d4fb39cdb4589ecab12a99eebdcaab 116 Pfam PF07885 Ion channel 37 105 1.9E-11 T 23-10-2018 IPR013099 Potassium channel domain A3L01_01540 f3d4fb39cdb4589ecab12a99eebdcaab 116 Gene3D G3DSA:1.10.287.70 11 116 2.1E-14 T 23-10-2018 A3L01_04120 a336f6bc762dafea5e5bbec81b58ff9b 455 PIRSF PIRSF004919 1 455 4.7E-156 T 23-10-2018 IPR025502 TldD A3L01_04120 a336f6bc762dafea5e5bbec81b58ff9b 455 SUPERFAMILY SSF111283 2 450 1.57E-96 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L01_04120 a336f6bc762dafea5e5bbec81b58ff9b 455 Gene3D G3DSA:3.30.2290.10 1 212 2.7E-16 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L01_04120 a336f6bc762dafea5e5bbec81b58ff9b 455 Pfam PF01523 Putative modulator of DNA gyrase 19 310 6.7E-45 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L01_04840 e165c6b0aaa075c6d89a7e670545c71c 182 SMART SM01022 1 102 3.3E-18 T 23-10-2018 IPR007374 ASCH domain A3L01_04840 e165c6b0aaa075c6d89a7e670545c71c 182 Pfam PF04266 ASCH domain 4 102 9.4E-21 T 23-10-2018 IPR007374 ASCH domain A3L01_04840 e165c6b0aaa075c6d89a7e670545c71c 182 SUPERFAMILY SSF88697 3 101 6.46E-19 T 23-10-2018 IPR015947 PUA-like superfamily A3L01_02690 9b0b81ed9730eb2fd46739a51fd646ef 407 Gene3D G3DSA:1.10.3270.10 1 73 2.3E-8 T 23-10-2018 IPR023282 Hydroxymethylglutaryl-CoA reductase, N-terminal GO:0004420 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L01_02690 9b0b81ed9730eb2fd46739a51fd646ef 407 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 94 114 4.3E-60 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L01_02690 9b0b81ed9730eb2fd46739a51fd646ef 407 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 184 202 4.3E-60 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L01_02690 9b0b81ed9730eb2fd46739a51fd646ef 407 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 275 301 4.3E-60 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L01_02690 9b0b81ed9730eb2fd46739a51fd646ef 407 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 63 84 4.3E-60 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L01_02690 9b0b81ed9730eb2fd46739a51fd646ef 407 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 224 249 4.3E-60 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L01_02690 9b0b81ed9730eb2fd46739a51fd646ef 407 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 327 348 4.3E-60 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L01_02690 9b0b81ed9730eb2fd46739a51fd646ef 407 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 31 407 7.3E-142 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L01_02690 9b0b81ed9730eb2fd46739a51fd646ef 407 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 186 200 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L01_02690 9b0b81ed9730eb2fd46739a51fd646ef 407 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 339 346 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L01_02690 9b0b81ed9730eb2fd46739a51fd646ef 407 SUPERFAMILY SSF56542 4 397 1.7E-94 T 23-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L01_02690 9b0b81ed9730eb2fd46739a51fd646ef 407 Gene3D G3DSA:3.30.70.420 128 243 4.5E-134 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L01_02690 9b0b81ed9730eb2fd46739a51fd646ef 407 TIGRFAM TIGR00533 HMG_CoA_R_NADP: hydroxymethylglutaryl-CoA reductase (NADPH) 1 407 1.6E-168 T 23-10-2018 IPR004554 Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type GO:0004420|GO:0008299|GO:0016021|GO:0050661|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L01_02690 9b0b81ed9730eb2fd46739a51fd646ef 407 SUPERFAMILY SSF55035 128 243 1.44E-39 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L01_02690 9b0b81ed9730eb2fd46739a51fd646ef 407 Gene3D G3DSA:3.90.770.10 74 394 4.5E-134 T 23-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L01_06810 80188fa16ce54270d0a68be6410859b4 103 SUPERFAMILY SSF50447 1 72 1.55E-16 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L01_06810 80188fa16ce54270d0a68be6410859b4 103 Pfam PF04410 Gar1/Naf1 RNA binding region 3 75 2.4E-9 T 23-10-2018 IPR007504 H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 GO:0001522|GO:0042254 A3L01_06810 80188fa16ce54270d0a68be6410859b4 103 ProDom PD064583 RNA-BINDING GAR1 COMPONENT RNP SNORNP HOMOLOG NUCLEOLAR PROCESSING RRNA VNG1366H 1 71 1.0E-16 T 23-10-2018 IPR020321 H/ACA ribonucleoprotein complex, subunit Gar1, archaea GO:0001522|GO:0042254 A3L01_06810 80188fa16ce54270d0a68be6410859b4 103 Gene3D G3DSA:2.40.10.230 1 75 4.6E-24 T 23-10-2018 IPR038664 H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain A3L01_01380 05f4cfc613fa67717b6baa5118da1455 262 Pfam PF00696 Amino acid kinase family 1 236 1.1E-41 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A3L01_01380 05f4cfc613fa67717b6baa5118da1455 262 Gene3D G3DSA:3.40.1160.10 1 261 1.9E-60 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L01_01380 05f4cfc613fa67717b6baa5118da1455 262 PIRSF PIRSF016496 1 262 2.0E-81 T 23-10-2018 IPR024192 Fosfomycin resistance kinase, FomA-type GO:0016301 KEGG: 00900+2.7.4.26|MetaCyc: PWY-6174|MetaCyc: PWY-7524 A3L01_01380 05f4cfc613fa67717b6baa5118da1455 262 SUPERFAMILY SSF53633 1 262 2.09E-33 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L01_04735 1a1ac8beef1fdf6c63c0713ae769525e 348 PIRSF PIRSF004869 54 347 3.0E-69 T 23-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted A3L01_04735 1a1ac8beef1fdf6c63c0713ae769525e 348 SUPERFAMILY SSF102114 137 331 1.18E-21 T 23-10-2018 A3L01_04735 1a1ac8beef1fdf6c63c0713ae769525e 348 Gene3D G3DSA:3.20.20.70 130 345 5.6E-21 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_04735 1a1ac8beef1fdf6c63c0713ae769525e 348 Pfam PF04055 Radical SAM superfamily 135 282 3.5E-18 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L01_04735 1a1ac8beef1fdf6c63c0713ae769525e 348 Pfam PF13353 4Fe-4S single cluster domain 133 221 2.3E-9 T 23-10-2018 A3L01_04340 a0a9c8615c6ad034ea0b7b30bce6eb5f 309 Pfam PF00005 ABC transporter 22 165 8.8E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_04340 a0a9c8615c6ad034ea0b7b30bce6eb5f 309 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_04340 a0a9c8615c6ad034ea0b7b30bce6eb5f 309 SMART SM00382 30 213 5.8E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_04340 a0a9c8615c6ad034ea0b7b30bce6eb5f 309 Gene3D G3DSA:3.40.50.300 2 239 4.4E-65 T 23-10-2018 A3L01_04340 a0a9c8615c6ad034ea0b7b30bce6eb5f 309 SUPERFAMILY SSF52540 4 227 2.93E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_04340 a0a9c8615c6ad034ea0b7b30bce6eb5f 309 Pfam PF13732 Domain of unknown function (DUF4162) 218 302 1.5E-8 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 A3L01_08505 41b15a2c3e7baf300ee6cdc39da7ff0f 186 SMART SM01007 7 181 5.5E-56 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal A3L01_08505 41b15a2c3e7baf300ee6cdc39da7ff0f 186 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 180 1.3E-46 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal A3L01_08505 41b15a2c3e7baf300ee6cdc39da7ff0f 186 Gene3D G3DSA:3.40.225.10 2 186 3.7E-58 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L01_08505 41b15a2c3e7baf300ee6cdc39da7ff0f 186 SUPERFAMILY SSF53639 3 184 1.79E-52 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L01_05400 ee2ffea4b84ad86f32f4d9a508300524 252 Pfam PF01026 TatD related DNase 3 249 1.6E-59 T 23-10-2018 IPR001130 TatD family GO:0016788 A3L01_05400 ee2ffea4b84ad86f32f4d9a508300524 252 Gene3D G3DSA:3.20.20.140 1 251 8.3E-66 T 23-10-2018 A3L01_05400 ee2ffea4b84ad86f32f4d9a508300524 252 PIRSF PIRSF005902 1 252 1.2E-61 T 23-10-2018 IPR001130 TatD family GO:0016788 A3L01_05400 ee2ffea4b84ad86f32f4d9a508300524 252 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 1 249 1.1E-70 T 23-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 A3L01_05400 ee2ffea4b84ad86f32f4d9a508300524 252 SUPERFAMILY SSF51556 1 250 7.22E-59 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L01_05770 578dee76823a1f3d34c5020011648bc7 241 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 53 190 2.4E-16 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A3L01_05770 578dee76823a1f3d34c5020011648bc7 241 SUPERFAMILY SSF48150 21 229 1.19E-62 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A3L01_05770 578dee76823a1f3d34c5020011648bc7 241 SMART SM00478 57 207 2.4E-57 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A3L01_05770 578dee76823a1f3d34c5020011648bc7 241 ProSitePatterns PS01155 Endonuclease III family signature. 123 152 - T 23-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 A3L01_05770 578dee76823a1f3d34c5020011648bc7 241 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 209 225 - T 23-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A3L01_05770 578dee76823a1f3d34c5020011648bc7 241 PIRSF PIRSF001435 19 233 8.7E-41 T 23-10-2018 A3L01_05770 578dee76823a1f3d34c5020011648bc7 241 Gene3D G3DSA:1.10.340.30 40 153 3.3E-63 T 23-10-2018 A3L01_05770 578dee76823a1f3d34c5020011648bc7 241 Pfam PF00633 Helix-hairpin-helix motif 120 149 1.6E-6 T 23-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 A3L01_05770 578dee76823a1f3d34c5020011648bc7 241 Gene3D G3DSA:1.10.1670.10 36 225 3.3E-63 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A3L01_05770 578dee76823a1f3d34c5020011648bc7 241 SMART SM00525 208 228 1.8E-5 T 23-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A3L01_05770 578dee76823a1f3d34c5020011648bc7 241 Hamap MF_00942 Endonuclease III [nth]. 21 231 33.298 T 23-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 A3L01_00460 3ec156542ddeb1992bb1be46a120f288 410 Hamap MF_00119 Translation initiation factor 2 subunit gamma [eif2g]. 4 409 61.381 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit A3L01_00460 3ec156542ddeb1992bb1be46a120f288 410 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 193 3.4E-18 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L01_00460 3ec156542ddeb1992bb1be46a120f288 410 SUPERFAMILY SSF50447 204 316 3.33E-38 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L01_00460 3ec156542ddeb1992bb1be46a120f288 410 PRINTS PR00315 GTP-binding elongation factor signature 13 26 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_00460 3ec156542ddeb1992bb1be46a120f288 410 PRINTS PR00315 GTP-binding elongation factor signature 140 149 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_00460 3ec156542ddeb1992bb1be46a120f288 410 PRINTS PR00315 GTP-binding elongation factor signature 103 114 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_00460 3ec156542ddeb1992bb1be46a120f288 410 PRINTS PR00315 GTP-binding elongation factor signature 87 97 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_00460 3ec156542ddeb1992bb1be46a120f288 410 TIGRFAM TIGR03680 eif2g_arch: translation initiation factor 2, gamma subunit 8 409 2.2E-206 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit A3L01_00460 3ec156542ddeb1992bb1be46a120f288 410 SUPERFAMILY SSF50465 317 409 2.63E-33 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A3L01_00460 3ec156542ddeb1992bb1be46a120f288 410 Gene3D G3DSA:2.40.30.10 204 318 1.7E-46 T 23-10-2018 A3L01_00460 3ec156542ddeb1992bb1be46a120f288 410 Pfam PF03144 Elongation factor Tu domain 2 231 311 6.1E-11 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A3L01_00460 3ec156542ddeb1992bb1be46a120f288 410 SUPERFAMILY SSF52540 4 209 2.7E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_00460 3ec156542ddeb1992bb1be46a120f288 410 Pfam PF09173 Initiation factor eIF2 gamma, C terminal 324 408 2.3E-31 T 23-10-2018 IPR015256 Translation initiation factor 2, gamma subunit, C-terminal A3L01_00460 3ec156542ddeb1992bb1be46a120f288 410 Pfam PF00009 Elongation factor Tu GTP binding domain 12 199 2.5E-36 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L01_00460 3ec156542ddeb1992bb1be46a120f288 410 Gene3D G3DSA:2.40.30.10 319 410 1.2E-34 T 23-10-2018 A3L01_00460 3ec156542ddeb1992bb1be46a120f288 410 Gene3D G3DSA:3.40.50.300 3 203 1.2E-67 T 23-10-2018 A3L01_06390 0059b70cbfb7db6b683148ee57efd4d7 282 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 22 57 4.2E-7 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A3L01_06390 0059b70cbfb7db6b683148ee57efd4d7 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 277 1.7E-26 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_06390 0059b70cbfb7db6b683148ee57efd4d7 282 SUPERFAMILY SSF161098 75 265 7.72E-27 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_06390 0059b70cbfb7db6b683148ee57efd4d7 282 Gene3D G3DSA:1.10.3720.10 68 279 1.7E-23 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_05885 d39221019e2b8c12dd60289a37bcea83 297 Pfam PF01751 Toprim domain 8 87 6.8E-8 T 23-10-2018 IPR006171 TOPRIM domain A3L01_05885 d39221019e2b8c12dd60289a37bcea83 297 SMART SM00493 5 84 9.0E-7 T 23-10-2018 IPR006171 TOPRIM domain A3L01_05885 d39221019e2b8c12dd60289a37bcea83 297 Gene3D G3DSA:3.40.1360.10 4 119 3.2E-6 T 23-10-2018 A3L01_07370 4baa8941a7545e4372b30593bfbf4956 500 Gene3D G3DSA:3.50.50.60 110 482 6.3E-145 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_07370 4baa8941a7545e4372b30593bfbf4956 500 Gene3D G3DSA:3.50.50.60 221 311 6.3E-145 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_07370 4baa8941a7545e4372b30593bfbf4956 500 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 264 354 7.7E-8 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L01_07370 4baa8941a7545e4372b30593bfbf4956 500 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 13 87 4.4E-15 T 23-10-2018 A3L01_07370 4baa8941a7545e4372b30593bfbf4956 500 SUPERFAMILY SSF51905 109 376 3.35E-22 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_07370 4baa8941a7545e4372b30593bfbf4956 500 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 110 259 5.5E-11 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L01_07370 4baa8941a7545e4372b30593bfbf4956 500 Gene3D G3DSA:3.10.20.440 1 95 3.0E-38 T 23-10-2018 A3L01_07370 4baa8941a7545e4372b30593bfbf4956 500 Gene3D G3DSA:1.10.10.1100 400 476 6.3E-145 T 23-10-2018 A3L01_02910 063c0260ad984ee201cbdbd86305e985 411 Pfam PF01676 Metalloenzyme superfamily 5 400 1.3E-53 T 23-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 A3L01_02910 063c0260ad984ee201cbdbd86305e985 411 Gene3D G3DSA:3.40.720.10 7 397 2.8E-141 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L01_02910 063c0260ad984ee201cbdbd86305e985 411 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 40 208 2.2E-53 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_02910 063c0260ad984ee201cbdbd86305e985 411 Gene3D G3DSA:3.30.70.2130 81 230 2.8E-141 T 23-10-2018 A3L01_02910 063c0260ad984ee201cbdbd86305e985 411 PIRSF PIRSF006392 1 407 7.9E-154 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_02910 063c0260ad984ee201cbdbd86305e985 411 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 7 401 7.3E-135 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_02910 063c0260ad984ee201cbdbd86305e985 411 SUPERFAMILY SSF53649 5 404 2.37E-44 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L01_02910 063c0260ad984ee201cbdbd86305e985 411 Hamap MF_01402_A 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 4 402 45.252 T 23-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_01400 aef0f30c71b63741ef72cdaee322862c 185 Pfam PF12798 4Fe-4S binding domain 110 127 0.14 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_01400 aef0f30c71b63741ef72cdaee322862c 185 Pfam PF12798 4Fe-4S binding domain 52 68 0.053 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_01400 aef0f30c71b63741ef72cdaee322862c 185 Gene3D G3DSA:3.30.70.20 6 146 2.6E-29 T 23-10-2018 A3L01_01400 aef0f30c71b63741ef72cdaee322862c 185 Pfam PF12800 4Fe-4S binding domain 8 23 0.041 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_01400 aef0f30c71b63741ef72cdaee322862c 185 Pfam PF00037 4Fe-4S binding domain 77 100 1.1E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_01400 aef0f30c71b63741ef72cdaee322862c 185 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 84 95 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_01400 aef0f30c71b63741ef72cdaee322862c 185 Gene3D G3DSA:3.30.70.20 58 109 2.6E-29 T 23-10-2018 A3L01_01400 aef0f30c71b63741ef72cdaee322862c 185 SUPERFAMILY SSF54862 9 145 1.31E-40 T 23-10-2018 A3L01_09475 6cc33e5e776697ef140199f8284cf5d9 312 SUPERFAMILY SSF161098 102 291 9.16E-23 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_09475 6cc33e5e776697ef140199f8284cf5d9 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 311 1.4E-24 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_09475 6cc33e5e776697ef140199f8284cf5d9 312 Gene3D G3DSA:1.10.3720.10 93 310 2.3E-20 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_00350 13649efd32edbedcd740e03a9d14fcf1 266 SUPERFAMILY SSF53335 21 193 4.91E-20 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_00350 13649efd32edbedcd740e03a9d14fcf1 266 Gene3D G3DSA:3.40.50.150 14 209 4.8E-15 T 23-10-2018 A3L01_00350 13649efd32edbedcd740e03a9d14fcf1 266 Pfam PF13649 Methyltransferase domain 45 144 2.1E-8 T 23-10-2018 A3L01_07950 a0594db133da45b9200d8b3f358173e5 192 Pfam PF13238 AAA domain 3 142 1.8E-18 T 23-10-2018 A3L01_07950 a0594db133da45b9200d8b3f358173e5 192 SUPERFAMILY SSF52540 1 188 1.95E-18 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_07950 a0594db133da45b9200d8b3f358173e5 192 Gene3D G3DSA:3.40.50.300 2 189 1.2E-41 T 23-10-2018 A3L01_08520 479ae2d72f3be850909fe59a74b6a17e 318 Pfam PF01555 DNA methylase 177 306 1.1E-11 T 23-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 A3L01_08520 479ae2d72f3be850909fe59a74b6a17e 318 Pfam PF01555 DNA methylase 43 120 8.9E-17 T 23-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 A3L01_08520 479ae2d72f3be850909fe59a74b6a17e 318 Gene3D G3DSA:3.40.50.150 159 317 3.4E-27 T 23-10-2018 A3L01_08520 479ae2d72f3be850909fe59a74b6a17e 318 Gene3D G3DSA:3.40.50.150 3 137 1.7E-20 T 23-10-2018 A3L01_08520 479ae2d72f3be850909fe59a74b6a17e 318 SUPERFAMILY SSF53335 46 130 1.14E-21 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_08520 479ae2d72f3be850909fe59a74b6a17e 318 SUPERFAMILY SSF53335 149 304 5.26E-26 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_08520 479ae2d72f3be850909fe59a74b6a17e 318 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 109 129 2.4E-9 T 23-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A3L01_08520 479ae2d72f3be850909fe59a74b6a17e 318 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 86 104 2.4E-9 T 23-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A3L01_01900 4c5c4048d08f3f128bc8b584b274b76e 67 Pfam PF02597 ThiS family 10 67 1.6E-11 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L01_01900 4c5c4048d08f3f128bc8b584b274b76e 67 Gene3D G3DSA:3.10.20.30 1 67 3.4E-26 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L01_01900 4c5c4048d08f3f128bc8b584b274b76e 67 SUPERFAMILY SSF54285 4 67 5.52E-14 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L01_01110 1334a742223019e325ffdc4e6fc49b55 130 Gene3D G3DSA:3.30.1490.10 70 128 1.5E-27 T 23-10-2018 A3L01_01110 1334a742223019e325ffdc4e6fc49b55 130 SUPERFAMILY SSF56047 3 130 1.31E-39 T 23-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01110 1334a742223019e325ffdc4e6fc49b55 130 Gene3D G3DSA:3.30.1370.30 1 69 7.0E-32 T 23-10-2018 A3L01_01110 1334a742223019e325ffdc4e6fc49b55 130 Pfam PF00410 Ribosomal protein S8 5 130 5.8E-28 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01110 1334a742223019e325ffdc4e6fc49b55 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01110 1334a742223019e325ffdc4e6fc49b55 130 Hamap MF_01302_A 30S ribosomal protein S8 [rpsH]. 2 130 38.258 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_04605 ae6e5850a7d64a2952590b6679f25f25 415 Pfam PF04409 Protein of unknown function (DUF530) 5 255 2.2E-23 T 23-10-2018 IPR007503 Protein of unknown function DUF530 A3L01_04605 ae6e5850a7d64a2952590b6679f25f25 415 PIRSF PIRSF018863 1 415 7.5E-190 T 23-10-2018 IPR014496 Uncharacterised conserved protein UCP018863 A3L01_07580 461f6f72d1400ab3692bc281201ccd0d 280 PIRSF PIRSF006816 1 257 1.3E-45 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L01_07580 461f6f72d1400ab3692bc281201ccd0d 280 Gene3D G3DSA:2.40.30.10 1 92 8.2E-14 T 23-10-2018 A3L01_07580 461f6f72d1400ab3692bc281201ccd0d 280 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 215 251 2.4E-12 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L01_07580 461f6f72d1400ab3692bc281201ccd0d 280 SUPERFAMILY SSF63380 1 92 3.14E-15 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L01_07580 461f6f72d1400ab3692bc281201ccd0d 280 SUPERFAMILY SSF52343 89 250 2.01E-12 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L01_07580 461f6f72d1400ab3692bc281201ccd0d 280 Gene3D G3DSA:3.40.50.80 100 205 6.0E-13 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L01_08235 f0caff21de496e7ec7b9fe09ce57a6e8 656 PIRSF PIRSF005023 1 656 2.4E-240 T 23-10-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 A3L01_08235 f0caff21de496e7ec7b9fe09ce57a6e8 656 Gene3D G3DSA:1.20.1270.30 63 267 6.7E-76 T 23-10-2018 IPR016101 CO dehydrogenase, alpha-bundle GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 A3L01_08235 f0caff21de496e7ec7b9fe09ce57a6e8 656 TIGRFAM TIGR01702 CO_DH_cata: carbon-monoxide dehydrogenase, catalytic subunit 123 656 9.9E-174 T 23-10-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 A3L01_08235 f0caff21de496e7ec7b9fe09ce57a6e8 656 SUPERFAMILY SSF56821 5 656 2.49E-193 T 23-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 A3L01_08235 f0caff21de496e7ec7b9fe09ce57a6e8 656 Pfam PF03063 Prismane/CO dehydrogenase family 46 636 2.9E-160 T 23-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 A3L01_08235 f0caff21de496e7ec7b9fe09ce57a6e8 656 Gene3D G3DSA:3.40.50.2030 438 653 3.3E-81 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 A3L01_08235 f0caff21de496e7ec7b9fe09ce57a6e8 656 Gene3D G3DSA:3.40.50.2030 268 435 2.0E-73 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 A3L01_06190 bddc473b21c47bee65a93f4a462911f0 388 SUPERFAMILY SSF48452 171 321 1.71E-6 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_06190 bddc473b21c47bee65a93f4a462911f0 388 SUPERFAMILY SSF48452 8 227 4.49E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_06190 bddc473b21c47bee65a93f4a462911f0 388 SMART SM00028 123 156 5.8 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L01_06190 bddc473b21c47bee65a93f4a462911f0 388 SMART SM00028 285 318 15.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L01_06190 bddc473b21c47bee65a93f4a462911f0 388 Gene3D G3DSA:1.25.40.10 7 166 7.5E-6 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_06190 bddc473b21c47bee65a93f4a462911f0 388 Gene3D G3DSA:1.25.40.10 167 384 5.4E-8 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_08025 11073c00a98ebf4afd9b92507c810b37 192 Pfam PF14470 Bacterial PH domain 13 105 1.3E-19 T 23-10-2018 IPR039519 YokE-like, PH domain A3L01_08025 11073c00a98ebf4afd9b92507c810b37 192 Pfam PF09851 Short C-terminal domain 162 189 2.9E-11 T 23-10-2018 IPR018649 SHOCT domain A3L01_03765 cd3512b67bfae3ba22b2dbb56de9f558 234 Pfam PF06745 KaiC 6 228 5.6E-51 T 23-10-2018 IPR014774 KaiC-like domain A3L01_03765 cd3512b67bfae3ba22b2dbb56de9f558 234 SUPERFAMILY SSF52540 5 227 7.28E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_03765 cd3512b67bfae3ba22b2dbb56de9f558 234 Gene3D G3DSA:3.40.50.300 3 231 6.2E-57 T 23-10-2018 A3L01_03765 cd3512b67bfae3ba22b2dbb56de9f558 234 PRINTS PR01874 DNA repair protein radA signature 15 43 1.6E-8 T 23-10-2018 A3L01_03765 cd3512b67bfae3ba22b2dbb56de9f558 234 PRINTS PR01874 DNA repair protein radA signature 57 74 1.6E-8 T 23-10-2018 A3L01_04000 38bab41d2b56f169b66ceaee5bef526a 88 ProDom PD012670 RIBOSOMAL L35A 60S RIBONUCLEOPROTEIN L35A L35AE 50S RNA-BINDING TRNA-BINDING SEQUENCE 5 87 3.0E-31 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_04000 38bab41d2b56f169b66ceaee5bef526a 88 Hamap MF_00573 50S ribosomal protein L35Ae [rpl35ae]. 4 88 23.596 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_04000 38bab41d2b56f169b66ceaee5bef526a 88 Pfam PF01247 Ribosomal protein L35Ae 5 87 2.6E-14 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_04000 38bab41d2b56f169b66ceaee5bef526a 88 Gene3D G3DSA:2.40.10.190 3 88 2.0E-23 T 23-10-2018 IPR038661 Ribosomal protein L35A superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_04000 38bab41d2b56f169b66ceaee5bef526a 88 ProSitePatterns PS01105 Ribosomal protein L35Ae signature. 56 77 - T 23-10-2018 IPR018266 Ribosomal protein L35Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_04000 38bab41d2b56f169b66ceaee5bef526a 88 SUPERFAMILY SSF50447 5 87 1.15E-22 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L01_05655 b0342a66d462ac2caedd0bff7b1942f8 253 Pfam PF02361 Cobalt transport protein 11 204 4.1E-29 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component A3L01_09120 f906e29c6c9e1c7114dae1844e77ae72 424 SUPERFAMILY SSF51338 1 423 2.45E-37 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L01_09120 f906e29c6c9e1c7114dae1844e77ae72 424 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 2 424 48.114 T 23-10-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 A3L01_09120 f906e29c6c9e1c7114dae1844e77ae72 424 Gene3D G3DSA:3.20.20.140 55 344 3.3E-156 T 23-10-2018 A3L01_09120 f906e29c6c9e1c7114dae1844e77ae72 424 Pfam PF01979 Amidohydrolase family 51 397 2.6E-76 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A3L01_09120 f906e29c6c9e1c7114dae1844e77ae72 424 Gene3D G3DSA:2.30.40.10 4 415 3.3E-156 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L01_09120 f906e29c6c9e1c7114dae1844e77ae72 424 SUPERFAMILY SSF51556 54 347 1.05E-103 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L01_10090 3c18965ef48088e5935ef133f566425c 340 SUPERFAMILY SSF159071 255 339 6.67E-19 T 23-10-2018 A3L01_10090 3c18965ef48088e5935ef133f566425c 340 Pfam PF11495 Archaeal transcriptional regulator TrmB 112 338 4.5E-52 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal A3L01_10090 3c18965ef48088e5935ef133f566425c 340 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 77 4.4E-25 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L01_10090 3c18965ef48088e5935ef133f566425c 340 Gene3D G3DSA:1.10.10.10 2 99 7.1E-30 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_10090 3c18965ef48088e5935ef133f566425c 340 SUPERFAMILY SSF46785 4 91 1.5E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_09285 7d95278bf682aaab50a688590baf863b 317 Gene3D G3DSA:1.10.8.300 202 311 1.7E-37 T 23-10-2018 A3L01_09285 7d95278bf682aaab50a688590baf863b 317 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 40 170 1.5E-67 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A3L01_09285 7d95278bf682aaab50a688590baf863b 317 SUPERFAMILY SSF52540 15 287 2.28E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_09285 7d95278bf682aaab50a688590baf863b 317 Gene3D G3DSA:3.40.50.300 21 187 5.3E-48 T 23-10-2018 A3L01_09285 7d95278bf682aaab50a688590baf863b 317 PIRSF PIRSF002849 1 316 1.1E-139 T 23-10-2018 A3L01_10255 900f01e394b48de359ab41395be0b0e8 442 SUPERFAMILY SSF53649 3 403 2.36E-35 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L01_10255 900f01e394b48de359ab41395be0b0e8 442 Pfam PF00884 Sulfatase 4 319 2.0E-20 T 23-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 A3L01_09520 6b7fe162e23777e76eaaab11944530a4 83 Pfam PF01998 Protein of unknown function DUF131 33 75 6.6E-14 T 23-10-2018 IPR002849 Protein of unknown function DUF131 A3L01_08430 6db40ef61d4eebb9a5088b392dfc897d 186 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 186 28.16 T 23-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L01_08430 6db40ef61d4eebb9a5088b392dfc897d 186 SUPERFAMILY SSF53271 9 173 1.2E-47 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L01_08430 6db40ef61d4eebb9a5088b392dfc897d 186 Pfam PF00156 Phosphoribosyl transferase domain 38 166 3.5E-23 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L01_08430 6db40ef61d4eebb9a5088b392dfc897d 186 Gene3D G3DSA:3.40.50.2020 1 179 1.7E-60 T 23-10-2018 A3L01_08430 6db40ef61d4eebb9a5088b392dfc897d 186 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 14 174 1.5E-51 T 23-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L01_04355 82db0a96e98c31861c842aa6f899b20d 479 Gene3D G3DSA:3.90.1860.10 1 479 3.7E-227 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A3L01_04355 82db0a96e98c31861c842aa6f899b20d 479 SUPERFAMILY SSF103365 2 479 1.83E-184 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A3L01_04355 82db0a96e98c31861c842aa6f899b20d 479 Pfam PF01139 tRNA-splicing ligase RtcB 45 479 2.5E-181 T 23-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A3L01_02545 79b5b6b9f46b8bf396e1e70b2d640d40 183 SUPERFAMILY SSF55486 19 173 2.43E-15 T 23-10-2018 A3L01_02545 79b5b6b9f46b8bf396e1e70b2d640d40 183 Hamap MF_01842 Archaemetzincin [amzA]. 1 176 34.754 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 A3L01_02545 79b5b6b9f46b8bf396e1e70b2d640d40 183 Pfam PF07998 Peptidase family M54 14 177 6.7E-30 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 A3L01_02545 79b5b6b9f46b8bf396e1e70b2d640d40 183 Gene3D G3DSA:3.40.390.10 7 182 1.5E-51 T 23-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 A3L01_02545 79b5b6b9f46b8bf396e1e70b2d640d40 183 PIRSF PIRSF005785 1 183 3.6E-61 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 A3L01_07330 c6519e687780924efc1ca46a18e5d6dd 166 Pfam PF01965 DJ-1/PfpI family 1 163 7.1E-59 T 23-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A3L01_07330 c6519e687780924efc1ca46a18e5d6dd 166 SUPERFAMILY SSF52317 1 165 1.72E-52 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_07330 c6519e687780924efc1ca46a18e5d6dd 166 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 2 165 4.5E-66 T 23-10-2018 IPR006286 Deglycase PfpI A3L01_07330 c6519e687780924efc1ca46a18e5d6dd 166 Gene3D G3DSA:3.40.50.880 1 166 2.9E-53 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_05260 95e51db7cc6ad90579e335f2459f74d0 220 Pfam PF00753 Metallo-beta-lactamase superfamily 22 142 1.4E-8 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_05260 95e51db7cc6ad90579e335f2459f74d0 220 Gene3D G3DSA:3.60.15.10 111 220 5.8E-20 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_05260 95e51db7cc6ad90579e335f2459f74d0 220 SUPERFAMILY SSF56281 4 217 2.1E-24 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_05260 95e51db7cc6ad90579e335f2459f74d0 220 Gene3D G3DSA:3.60.15.10 1 97 9.6E-20 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_05260 95e51db7cc6ad90579e335f2459f74d0 220 SMART SM00849 19 191 2.2E-7 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_00085 386caea41c5f38e4817f40633e5613cc 234 ProSitePatterns PS01058 SAICAR synthetase signature 2. 171 179 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L01_00085 386caea41c5f38e4817f40633e5613cc 234 SUPERFAMILY SSF56104 6 233 1.67E-82 T 23-10-2018 A3L01_00085 386caea41c5f38e4817f40633e5613cc 234 ProSitePatterns PS01057 SAICAR synthetase signature 1. 85 99 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L01_00085 386caea41c5f38e4817f40633e5613cc 234 Pfam PF01259 SAICAR synthetase 7 227 5.6E-69 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L01_00085 386caea41c5f38e4817f40633e5613cc 234 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 233 33.34 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L01_00085 386caea41c5f38e4817f40633e5613cc 234 Gene3D G3DSA:3.30.200.20 21 231 1.2E-96 T 23-10-2018 A3L01_00085 386caea41c5f38e4817f40633e5613cc 234 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 2 230 2.2E-77 T 23-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A3L01_00085 386caea41c5f38e4817f40633e5613cc 234 Gene3D G3DSA:3.30.470.20 84 219 1.2E-96 T 23-10-2018 A3L01_07650 87819ed4aabc1d420d5fde8f676bd36d 374 Gene3D G3DSA:1.20.1250.20 1 185 1.1E-43 T 23-10-2018 A3L01_07650 87819ed4aabc1d420d5fde8f676bd36d 374 Gene3D G3DSA:1.20.1250.20 193 370 3.0E-26 T 23-10-2018 A3L01_07650 87819ed4aabc1d420d5fde8f676bd36d 374 Pfam PF07690 Major Facilitator Superfamily 11 330 1.1E-47 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L01_07650 87819ed4aabc1d420d5fde8f676bd36d 374 SUPERFAMILY SSF103473 2 360 3.92E-71 T 23-10-2018 IPR036259 MFS transporter superfamily A3L01_07780 68dee44c648970d0ca6ee03f1d73e594 308 Pfam PF04055 Radical SAM superfamily 16 172 6.6E-32 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L01_07780 68dee44c648970d0ca6ee03f1d73e594 308 Hamap MF_01225_A GTP 3',8-cyclase [moaA]. 3 308 43.454 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 A3L01_07780 68dee44c648970d0ca6ee03f1d73e594 308 SUPERFAMILY SSF102114 3 302 9.29E-69 T 23-10-2018 A3L01_07780 68dee44c648970d0ca6ee03f1d73e594 308 TIGRFAM TIGR02668 moaA_archaeal: probable molybdenum cofactor biosynthesis protein A 3 308 1.3E-124 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 A3L01_07780 68dee44c648970d0ca6ee03f1d73e594 308 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 18 29 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L01_07780 68dee44c648970d0ca6ee03f1d73e594 308 Gene3D G3DSA:3.20.20.70 1 306 9.0E-77 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_07780 68dee44c648970d0ca6ee03f1d73e594 308 SMART SM00729 12 214 2.8E-17 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L01_07780 68dee44c648970d0ca6ee03f1d73e594 308 Pfam PF13353 4Fe-4S single cluster domain 19 104 1.7E-9 T 23-10-2018 A3L01_07780 68dee44c648970d0ca6ee03f1d73e594 308 Pfam PF06463 Molybdenum Cofactor Synthesis C 180 307 6.7E-22 T 23-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L01_07825 55de527bc01eb22e1d3d00b2145fa48e 167 Pfam PF00583 Acetyltransferase (GNAT) family 28 137 8.7E-28 T 23-10-2018 IPR000182 GNAT domain A3L01_07825 55de527bc01eb22e1d3d00b2145fa48e 167 SUPERFAMILY SSF55729 16 157 4.25E-38 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L01_07825 55de527bc01eb22e1d3d00b2145fa48e 167 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 27 156 1.2E-33 T 23-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 A3L01_07825 55de527bc01eb22e1d3d00b2145fa48e 167 Gene3D G3DSA:3.40.630.30 16 163 6.7E-48 T 23-10-2018 A3L01_06610 b7a66c6b8e0482fe574e44639bcc1c75 134 Pfam PF01894 Uncharacterised protein family UPF0047 17 131 1.5E-37 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L01_06610 b7a66c6b8e0482fe574e44639bcc1c75 134 Gene3D G3DSA:2.60.120.460 1 133 9.0E-50 T 23-10-2018 IPR035917 YjbQ-like superfamily A3L01_06610 b7a66c6b8e0482fe574e44639bcc1c75 134 PIRSF PIRSF004681 2 133 9.0E-40 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L01_06610 b7a66c6b8e0482fe574e44639bcc1c75 134 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 4 131 1.1E-41 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L01_06610 b7a66c6b8e0482fe574e44639bcc1c75 134 SUPERFAMILY SSF111038 2 131 1.1E-41 T 23-10-2018 IPR035917 YjbQ-like superfamily A3L01_07400 19e394c59e82fb4b8eb4618822469057 435 SUPERFAMILY SSF51735 2 164 6.49E-28 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_07400 19e394c59e82fb4b8eb4618822469057 435 SUPERFAMILY SSF56327 167 421 1.81E-39 T 23-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A3L01_07400 19e394c59e82fb4b8eb4618822469057 435 Gene3D G3DSA:3.90.1820.20 1 419 3.7E-86 T 23-10-2018 A3L01_07400 19e394c59e82fb4b8eb4618822469057 435 Pfam PF02056 Family 4 glycosyl hydrolase 2 182 4.9E-24 T 23-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A3L01_07400 19e394c59e82fb4b8eb4618822469057 435 PRINTS PR00732 Glycosyl hydrolase family 4 signature 92 105 1.8E-18 T 23-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A3L01_07400 19e394c59e82fb4b8eb4618822469057 435 PRINTS PR00732 Glycosyl hydrolase family 4 signature 137 154 1.8E-18 T 23-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A3L01_07400 19e394c59e82fb4b8eb4618822469057 435 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 1.8E-18 T 23-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A3L01_07400 19e394c59e82fb4b8eb4618822469057 435 PRINTS PR00732 Glycosyl hydrolase family 4 signature 189 201 1.8E-18 T 23-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A3L01_07400 19e394c59e82fb4b8eb4618822469057 435 PRINTS PR00732 Glycosyl hydrolase family 4 signature 108 128 1.8E-18 T 23-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A3L01_07400 19e394c59e82fb4b8eb4618822469057 435 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 193 397 2.2E-31 T 23-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 A3L01_10265 d2e0692bdd2fbb9e7e57672e8915bb67 303 Gene3D G3DSA:3.40.50.720 3 271 8.4E-96 T 23-10-2018 A3L01_10265 d2e0692bdd2fbb9e7e57672e8915bb67 303 Gene3D G3DSA:3.90.25.10 164 277 8.4E-96 T 23-10-2018 A3L01_10265 d2e0692bdd2fbb9e7e57672e8915bb67 303 SUPERFAMILY SSF51735 1 283 4.39E-84 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_10265 d2e0692bdd2fbb9e7e57672e8915bb67 303 Pfam PF04321 RmlD substrate binding domain 1 281 3.8E-86 T 23-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 A3L01_10265 d2e0692bdd2fbb9e7e57672e8915bb67 303 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 282 1.0E-106 T 23-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 A3L01_03590 a201dba63a88c9d411419b8a39e16a98 93 SUPERFAMILY SSF56784 22 55 2.25E-5 T 23-10-2018 IPR036412 HAD-like superfamily A3L01_04350 d6fff0a4c5b44ed077ed75502e720d95 308 Pfam PF12679 ABC-2 family transporter protein 5 307 4.5E-59 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A3L01_04225 a6a0a5fd2a514ea25895c50f43959444 396 Pfam PF03454 MoeA C-terminal region (domain IV) 329 395 1.1E-14 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L01_04225 a6a0a5fd2a514ea25895c50f43959444 396 Pfam PF00994 Probable molybdopterin binding domain 186 315 3.7E-16 T 23-10-2018 IPR001453 MoaB/Mog domain A3L01_04225 a6a0a5fd2a514ea25895c50f43959444 396 SUPERFAMILY SSF63882 7 181 3.14E-59 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L01_04225 a6a0a5fd2a514ea25895c50f43959444 396 SMART SM00852 186 317 2.9E-28 T 23-10-2018 IPR001453 MoaB/Mog domain A3L01_04225 a6a0a5fd2a514ea25895c50f43959444 396 Gene3D G3DSA:3.90.105.10 27 181 5.6E-110 T 23-10-2018 A3L01_04225 a6a0a5fd2a514ea25895c50f43959444 396 SUPERFAMILY SSF63867 327 396 1.7E-17 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L01_04225 a6a0a5fd2a514ea25895c50f43959444 396 SUPERFAMILY SSF53218 181 321 1.19E-33 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L01_04225 a6a0a5fd2a514ea25895c50f43959444 396 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 173 7.9E-48 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L01_04225 a6a0a5fd2a514ea25895c50f43959444 396 Gene3D G3DSA:2.40.340.10 320 396 4.2E-25 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L01_04225 a6a0a5fd2a514ea25895c50f43959444 396 Gene3D G3DSA:3.40.980.10 19 314 5.6E-110 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L01_04225 a6a0a5fd2a514ea25895c50f43959444 396 Gene3D G3DSA:2.170.190.11 50 148 5.6E-110 T 23-10-2018 A3L01_07665 1704478d92f29b2735fd7417679851a3 315 SUPERFAMILY SSF102114 15 240 1.96E-35 T 23-10-2018 A3L01_07665 1704478d92f29b2735fd7417679851a3 315 SMART SM00729 27 235 3.4E-12 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L01_07665 1704478d92f29b2735fd7417679851a3 315 Pfam PF04055 Radical SAM superfamily 36 192 5.0E-8 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L01_07665 1704478d92f29b2735fd7417679851a3 315 Gene3D G3DSA:3.20.20.70 13 241 8.8E-24 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_05685 96e2568cc726938abf07a71e2f570c19 375 Pfam PF00579 tRNA synthetases class I (W and Y) 33 351 9.8E-44 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L01_05685 96e2568cc726938abf07a71e2f570c19 375 PIRSF PIRSF006588 1 375 6.0E-129 T 23-10-2018 IPR023617 Tyrosine-tRNA ligase, archaeal/eukaryotic-type GO:0004831 KEGG: 00970+6.1.1.1 A3L01_05685 96e2568cc726938abf07a71e2f570c19 375 Gene3D G3DSA:1.10.240.10 227 375 2.4E-55 T 23-10-2018 A3L01_05685 96e2568cc726938abf07a71e2f570c19 375 SUPERFAMILY SSF52374 2 363 2.02E-66 T 23-10-2018 A3L01_05685 96e2568cc726938abf07a71e2f570c19 375 Gene3D G3DSA:3.40.50.620 1 226 3.8E-59 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_05685 96e2568cc726938abf07a71e2f570c19 375 Hamap MF_02009 Tyrosine--tRNA ligase [tyrS]. 5 359 47.761 T 23-10-2018 IPR023678 Tyrosine-tRNA ligase, type 4 GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A3L01_09840 6cca0d0f3c5ae0cfc44660529d97bdf5 102 Hamap MF_00312 V-type ATP synthase subunit F [atpF]. 1 101 19.548 T 23-10-2018 IPR022944 ATPase, V1 complex, subunit F, bacterial/archaeal A3L01_09840 6cca0d0f3c5ae0cfc44660529d97bdf5 102 Gene3D G3DSA:3.40.50.10580 1 102 1.7E-32 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L01_09840 6cca0d0f3c5ae0cfc44660529d97bdf5 102 Pfam PF01990 ATP synthase (F/14-kDa) subunit 3 90 4.5E-18 T 23-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L01_09840 6cca0d0f3c5ae0cfc44660529d97bdf5 102 SUPERFAMILY SSF159468 3 100 7.72E-20 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L01_00255 20bfb507bd5fb6d654ef96a5b896e3e2 340 Pfam PF17231 Family of unknown function (DUF5305) 122 328 4.0E-15 T 23-10-2018 IPR035185 Protein of unknown function DUF5305 A3L01_01790 1f359c05f2169be0613a0e64fa95d9a6 454 SUPERFAMILY SSF53613 2 452 3.14E-150 T 23-10-2018 IPR029056 Ribokinase-like A3L01_01790 1f359c05f2169be0613a0e64fa95d9a6 454 Hamap MF_00809 ADP-dependent glucokinase [glkA]. 1 453 58.84 T 23-10-2018 IPR031299 ADP-dependent glucokinase, archaeal KEGG: 00010+2.7.1.147|MetaCyc: PWY-6855 A3L01_01790 1f359c05f2169be0613a0e64fa95d9a6 454 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 24 447 1.3E-92 T 23-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 A3L01_01790 1f359c05f2169be0613a0e64fa95d9a6 454 Gene3D G3DSA:3.40.1190.20 24 447 3.3E-150 T 23-10-2018 IPR029056 Ribokinase-like A3L01_01790 1f359c05f2169be0613a0e64fa95d9a6 454 Gene3D G3DSA:3.30.1110.20 31 203 3.3E-150 T 23-10-2018 A3L01_02595 9269d074b0decdee6ecd10e189f07474 95 Gene3D G3DSA:3.30.1360.10 1 94 9.6E-34 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_02595 9269d074b0decdee6ecd10e189f07474 95 Pfam PF13656 RNA polymerase Rpb3/Rpb11 dimerisation domain 13 83 1.7E-20 T 23-10-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 A3L01_02595 9269d074b0decdee6ecd10e189f07474 95 Hamap MF_00261 DNA-directed RNA polymerase subunit L [rpoL]. 1 89 19.926 T 23-10-2018 IPR022905 DNA-directed RNA polymerase subunit L (Rpo11) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_02595 9269d074b0decdee6ecd10e189f07474 95 ProSitePatterns PS01154 RNA polymerases L / 13 to 16 Kd subunits signature. 17 48 - T 23-10-2018 IPR008193 DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 A3L01_02595 9269d074b0decdee6ecd10e189f07474 95 SUPERFAMILY SSF55257 1 93 3.66E-25 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_06065 f2b8e856b402724e0c7a5896937276b0 281 PIRSF PIRSF015853 1 278 2.6E-92 T 23-10-2018 IPR007035 Peptidase M55, D-aminopeptidase A3L01_06065 f2b8e856b402724e0c7a5896937276b0 281 SUPERFAMILY SSF63992 2 276 8.24E-79 T 23-10-2018 IPR036177 Peptidase M55, D-aminopeptidase superfamily A3L01_06065 f2b8e856b402724e0c7a5896937276b0 281 Gene3D G3DSA:3.40.50.10780 2 218 3.3E-74 T 23-10-2018 IPR027476 D-aminopeptidase, N-terminal A3L01_06065 f2b8e856b402724e0c7a5896937276b0 281 Pfam PF04951 D-aminopeptidase 2 266 1.7E-78 T 23-10-2018 IPR007035 Peptidase M55, D-aminopeptidase A3L01_06065 f2b8e856b402724e0c7a5896937276b0 281 Gene3D G3DSA:3.30.1360.130 119 265 3.3E-74 T 23-10-2018 A3L01_09910 6b9d3372b265d55ff2f062f74adb8b01 818 SUPERFAMILY SSF53850 15 369 9.64E-23 T 23-10-2018 A3L01_09910 6b9d3372b265d55ff2f062f74adb8b01 818 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 54 349 1.1E-17 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain A3L01_09910 6b9d3372b265d55ff2f062f74adb8b01 818 Gene3D G3DSA:3.40.190.10 33 170 1.1E-5 T 23-10-2018 A3L01_09910 6b9d3372b265d55ff2f062f74adb8b01 818 Gene3D G3DSA:3.10.105.10 175 409 2.3E-14 T 23-10-2018 A3L01_01870 14b74e6dd00f1c241fbd3a878a9c7cc8 59 SUPERFAMILY SSF46785 5 56 1.16E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_01870 14b74e6dd00f1c241fbd3a878a9c7cc8 59 Pfam PF08279 HTH domain 7 49 1.7E-4 T 23-10-2018 IPR013196 Helix-turn-helix, type 11 A3L01_01870 14b74e6dd00f1c241fbd3a878a9c7cc8 59 Gene3D G3DSA:1.10.10.10 3 56 1.9E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_02125 b43dbd1dc874e388d97baf61e295831a 464 Gene3D G3DSA:3.40.1360.10 198 294 1.2E-12 T 23-10-2018 A3L01_02125 b43dbd1dc874e388d97baf61e295831a 464 SMART SM00493 200 269 2.0E-12 T 23-10-2018 IPR006171 TOPRIM domain A3L01_02125 b43dbd1dc874e388d97baf61e295831a 464 Hamap MF_00007 DNA primase DnaG [dnaG]. 36 463 36.362 T 23-10-2018 IPR020607 DNA primase DnaG, archaea GO:0000178|GO:0003896|GO:0008143 A3L01_02125 b43dbd1dc874e388d97baf61e295831a 464 SUPERFAMILY SSF56731 199 312 6.02E-11 T 23-10-2018 A3L01_02125 b43dbd1dc874e388d97baf61e295831a 464 Pfam PF13662 Toprim domain 201 284 1.4E-12 T 23-10-2018 IPR006171 TOPRIM domain A3L01_02855 55aa1bb955f32cb68bcc25b628ce6fc7 362 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 113 3.5E-19 T 23-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 A3L01_02855 55aa1bb955f32cb68bcc25b628ce6fc7 362 Gene3D G3DSA:3.40.50.720 2 349 3.0E-131 T 23-10-2018 A3L01_02855 55aa1bb955f32cb68bcc25b628ce6fc7 362 SUPERFAMILY SSF51735 1 169 3.89E-22 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_02855 55aa1bb955f32cb68bcc25b628ce6fc7 362 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 117 349 7.1E-31 T 23-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 A3L01_02855 55aa1bb955f32cb68bcc25b628ce6fc7 362 Gene3D G3DSA:3.30.360.10 118 299 3.0E-131 T 23-10-2018 A3L01_02855 55aa1bb955f32cb68bcc25b628ce6fc7 362 SUPERFAMILY SSF55347 118 262 1.37E-39 T 23-10-2018 A3L01_04070 0abe7beba6260d20cb06a14fc56e85c1 171 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 1 164 1.6E-30 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 A3L01_04070 0abe7beba6260d20cb06a14fc56e85c1 171 Gene3D G3DSA:2.40.320.10 1 171 1.6E-49 T 23-10-2018 A3L01_04070 0abe7beba6260d20cb06a14fc56e85c1 171 SUPERFAMILY SSF55154 1 164 1.47E-39 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 A3L01_04070 0abe7beba6260d20cb06a14fc56e85c1 171 SMART SM01118 1 166 8.4E-12 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A3L01_04070 0abe7beba6260d20cb06a14fc56e85c1 171 Pfam PF01928 CYTH domain 2 160 3.8E-25 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A3L01_04070 0abe7beba6260d20cb06a14fc56e85c1 171 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 2 141 3.0E-47 T 23-10-2018 A3L01_01310 c03ddc3936822aa49e56724a84d46bcb 238 Pfam PF00156 Phosphoribosyl transferase domain 96 215 5.6E-13 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L01_01310 c03ddc3936822aa49e56724a84d46bcb 238 SUPERFAMILY SSF47413 15 62 7.95E-5 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L01_01310 c03ddc3936822aa49e56724a84d46bcb 238 Gene3D G3DSA:3.40.50.2020 64 238 2.7E-40 T 23-10-2018 A3L01_01310 c03ddc3936822aa49e56724a84d46bcb 238 Pfam PF01381 Helix-turn-helix 17 62 1.3E-5 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L01_01310 c03ddc3936822aa49e56724a84d46bcb 238 SUPERFAMILY SSF53271 75 237 3.15E-35 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L01_04820 2ddb41e57c3ffdc375c39c701a032184 396 Gene3D G3DSA:1.20.1250.20 6 382 1.3E-22 T 23-10-2018 A3L01_04820 2ddb41e57c3ffdc375c39c701a032184 396 Pfam PF07690 Major Facilitator Superfamily 11 347 1.6E-12 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L01_04820 2ddb41e57c3ffdc375c39c701a032184 396 SUPERFAMILY SSF103473 14 380 1.27E-23 T 23-10-2018 IPR036259 MFS transporter superfamily A3L01_05985 ef44521caf392344ea7c11fb4e347f87 168 SUPERFAMILY SSF88723 70 115 3.86E-7 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L01_05985 ef44521caf392344ea7c11fb4e347f87 168 Pfam PF17146 PIN domain of ribonuclease 5 87 3.6E-18 T 23-10-2018 IPR033411 Ribonuclease, PIN domain Reactome: R-HSA-6791226 A3L01_05985 ef44521caf392344ea7c11fb4e347f87 168 Gene3D G3DSA:2.20.28.10 119 156 6.4E-19 T 23-10-2018 A3L01_05985 ef44521caf392344ea7c11fb4e347f87 168 Gene3D G3DSA:3.40.50.1010 1 118 1.8E-41 T 23-10-2018 A3L01_05985 ef44521caf392344ea7c11fb4e347f87 168 SMART SM00670 2 100 9.0E-4 T 23-10-2018 IPR002716 PIN domain A3L01_05370 2076ad37a94bb7f1fadfef57fa60d5a0 351 SUPERFAMILY SSF55031 155 271 2.54E-10 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A3L01_05370 2076ad37a94bb7f1fadfef57fa60d5a0 351 SUPERFAMILY SSF53187 8 343 1.74E-40 T 23-10-2018 A3L01_05370 2076ad37a94bb7f1fadfef57fa60d5a0 351 Gene3D G3DSA:3.30.70.360 155 264 1.2E-60 T 23-10-2018 A3L01_05370 2076ad37a94bb7f1fadfef57fa60d5a0 351 Pfam PF07687 Peptidase dimerisation domain 152 254 3.9E-9 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A3L01_05370 2076ad37a94bb7f1fadfef57fa60d5a0 351 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 87 124 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A3L01_05370 2076ad37a94bb7f1fadfef57fa60d5a0 351 Pfam PF01546 Peptidase family M20/M25/M40 64 343 2.0E-25 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A3L01_05370 2076ad37a94bb7f1fadfef57fa60d5a0 351 Gene3D G3DSA:3.40.630.10 14 336 1.2E-60 T 23-10-2018 A3L01_06830 5ba9c9eb51a974fac39e13898433dde4 487 PIRSF PIRSF018875 1 483 2.3E-82 T 23-10-2018 IPR018646 Membrane protein of 12 TMs A3L01_06830 5ba9c9eb51a974fac39e13898433dde4 487 Pfam PF09847 Membrane protein of 12 TMs 40 476 6.9E-81 T 23-10-2018 IPR018646 Membrane protein of 12 TMs A3L01_02110 a95018f1971f030491d90d22054e179e 622 SUPERFAMILY SSF53795 241 603 9.84E-107 T 23-10-2018 A3L01_02110 a95018f1971f030491d90d22054e179e 622 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 15 604 36.303 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L01_02110 a95018f1971f030491d90d22054e179e 622 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 241 603 1.7E-105 T 23-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L01_02110 a95018f1971f030491d90d22054e179e 622 Gene3D G3DSA:2.170.8.10 62 395 3.3E-148 T 23-10-2018 A3L01_02110 a95018f1971f030491d90d22054e179e 622 PIRSF PIRSF001348 2 607 4.1E-210 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L01_02110 a95018f1971f030491d90d22054e179e 622 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 265 273 - T 23-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L01_02110 a95018f1971f030491d90d22054e179e 622 Gene3D G3DSA:3.90.228.20 244 602 3.3E-148 T 23-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A3L01_02110 a95018f1971f030491d90d22054e179e 622 SUPERFAMILY SSF68923 8 240 1.73E-62 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A3L01_02110 a95018f1971f030491d90d22054e179e 622 Gene3D G3DSA:3.40.449.10 24 243 3.3E-148 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A3L01_02110 a95018f1971f030491d90d22054e179e 622 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 26 236 2.5E-57 T 23-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L01_05355 c7dd0d9b02648a4b5052588b1c8367bd 378 Pfam PF00465 Iron-containing alcohol dehydrogenase 6 367 1.9E-93 T 23-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A3L01_05355 c7dd0d9b02648a4b5052588b1c8367bd 378 Gene3D G3DSA:3.40.50.1970 1 183 4.5E-41 T 23-10-2018 A3L01_05355 c7dd0d9b02648a4b5052588b1c8367bd 378 SUPERFAMILY SSF56796 2 377 3.14E-95 T 23-10-2018 A3L01_05355 c7dd0d9b02648a4b5052588b1c8367bd 378 Gene3D G3DSA:1.20.1090.10 185 378 4.5E-53 T 23-10-2018 A3L01_04210 9561c06afc7af603dc11207c320e7b21 336 Gene3D G3DSA:3.40.50.10210 1 333 2.4E-127 T 23-10-2018 A3L01_04210 9561c06afc7af603dc11207c320e7b21 336 SUPERFAMILY SSF52733 18 327 2.62E-42 T 23-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 A3L01_04210 9561c06afc7af603dc11207c320e7b21 336 Hamap MF_01086 UPF0284 protein . 1 336 138.965 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative A3L01_04210 9561c06afc7af603dc11207c320e7b21 336 TIGRFAM TIGR00303 TIGR00303: TIGR00303 family protein 2 323 2.4E-102 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative A3L01_06165 c70911c9f42da0a335549643b12811a8 247 Gene3D G3DSA:3.40.50.300 1 243 3.4E-55 T 23-10-2018 A3L01_06165 c70911c9f42da0a335549643b12811a8 247 Pfam PF03029 Conserved hypothetical ATP binding protein 6 241 2.0E-48 T 23-10-2018 IPR004130 GPN-loop GTPase A3L01_06165 c70911c9f42da0a335549643b12811a8 247 SUPERFAMILY SSF52540 1 239 4.5E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_09895 d343760b3f9cc2c0e541e04adc7a5c22 301 Gene3D G3DSA:3.20.20.70 51 279 3.9E-29 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_09895 d343760b3f9cc2c0e541e04adc7a5c22 301 Pfam PF04055 Radical SAM superfamily 61 210 5.1E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L01_09895 d343760b3f9cc2c0e541e04adc7a5c22 301 SMART SM00729 56 253 2.3E-5 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L01_09895 d343760b3f9cc2c0e541e04adc7a5c22 301 SUPERFAMILY SSF102114 60 261 1.83E-29 T 23-10-2018 A3L01_00845 d05dd392cb11f89137e49933f4f36546 401 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 24 399 8.8E-158 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 A3L01_00845 d05dd392cb11f89137e49933f4f36546 401 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 23 395 3.2E-157 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 A3L01_00845 d05dd392cb11f89137e49933f4f36546 401 PIRSF PIRSF015658 1 401 2.4E-166 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 A3L01_01390 1ec04237a28fc20c4522f8eb9b67cf89 394 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.5E-20 T 23-10-2018 A3L01_01390 1ec04237a28fc20c4522f8eb9b67cf89 394 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 274 2.5E-20 T 23-10-2018 A3L01_01390 1ec04237a28fc20c4522f8eb9b67cf89 394 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 2.5E-20 T 23-10-2018 A3L01_01390 1ec04237a28fc20c4522f8eb9b67cf89 394 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 2.5E-20 T 23-10-2018 A3L01_01390 1ec04237a28fc20c4522f8eb9b67cf89 394 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 2.5E-20 T 23-10-2018 A3L01_01390 1ec04237a28fc20c4522f8eb9b67cf89 394 Gene3D G3DSA:3.50.50.60 111 343 8.2E-67 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_01390 1ec04237a28fc20c4522f8eb9b67cf89 394 Gene3D G3DSA:3.50.50.60 4 330 8.2E-67 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_01390 1ec04237a28fc20c4522f8eb9b67cf89 394 SUPERFAMILY SSF51905 3 304 1.28E-38 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_01390 1ec04237a28fc20c4522f8eb9b67cf89 394 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 3.6E-13 T 23-10-2018 A3L01_01390 1ec04237a28fc20c4522f8eb9b67cf89 394 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 3.6E-13 T 23-10-2018 A3L01_01390 1ec04237a28fc20c4522f8eb9b67cf89 394 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 274 3.6E-13 T 23-10-2018 A3L01_01390 1ec04237a28fc20c4522f8eb9b67cf89 394 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 274 3.9E-49 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L01_03940 627f9511c10369f3c18d19093c5fb655 95 SMART SM01152 9 84 7.6E-35 T 23-10-2018 IPR003746 Protein of unknown function DUF167 A3L01_03940 627f9511c10369f3c18d19093c5fb655 95 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 13 82 1.4E-24 T 23-10-2018 IPR003746 Protein of unknown function DUF167 A3L01_03940 627f9511c10369f3c18d19093c5fb655 95 Hamap MF_00634 UPF0235 protein YggU [yggU]. 9 95 20.824 T 23-10-2018 IPR003746 Protein of unknown function DUF167 A3L01_03940 627f9511c10369f3c18d19093c5fb655 95 SUPERFAMILY SSF69786 5 93 4.05E-28 T 23-10-2018 IPR036591 YggU-like superfamily A3L01_03940 627f9511c10369f3c18d19093c5fb655 95 Gene3D G3DSA:3.30.1200.10 1 95 3.0E-31 T 23-10-2018 IPR036591 YggU-like superfamily A3L01_03940 627f9511c10369f3c18d19093c5fb655 95 TIGRFAM TIGR00251 TIGR00251: TIGR00251 family protein 6 84 6.0E-29 T 23-10-2018 IPR005228 Conserved hypothetical protein CHP00251 A3L01_05805 409b07b48bbf576ebeea56cec5aded63 253 SUPERFAMILY SSF56059 20 236 1.11E-45 T 23-10-2018 A3L01_05805 409b07b48bbf576ebeea56cec5aded63 253 Gene3D G3DSA:3.30.470.20 17 232 4.2E-91 T 23-10-2018 A3L01_05805 409b07b48bbf576ebeea56cec5aded63 253 Pfam PF13549 ATP-grasp domain 12 234 5.7E-81 T 23-10-2018 A3L01_05805 409b07b48bbf576ebeea56cec5aded63 253 Gene3D G3DSA:3.30.1490.20 38 115 4.2E-91 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L01_07535 f66e07bc92a01c5167086e671e9eafb0 175 SUPERFAMILY SSF117916 76 173 3.27E-32 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L01_07535 f66e07bc92a01c5167086e671e9eafb0 175 Pfam PF01883 Iron-sulfur cluster assembly protein 79 152 9.2E-22 T 23-10-2018 IPR002744 MIP18 family-like A3L01_07535 f66e07bc92a01c5167086e671e9eafb0 175 Gene3D G3DSA:3.30.300.130 72 175 5.1E-36 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L01_08915 0723fce3c0b80590b5d57faea7d0ed1b 310 SUPERFAMILY SSF102114 77 286 5.1E-12 T 23-10-2018 A3L01_08915 0723fce3c0b80590b5d57faea7d0ed1b 310 Pfam PF13186 Iron-sulfur cluster-binding domain 225 281 8.5E-7 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A3L01_08915 0723fce3c0b80590b5d57faea7d0ed1b 310 Gene3D G3DSA:3.20.20.70 193 309 7.5E-11 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_08915 0723fce3c0b80590b5d57faea7d0ed1b 310 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 222 302 2.9E-10 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A3L01_07455 7e64cc00ef982433cfeae52449cbe0e1 90 Gene3D G3DSA:1.10.10.1100 1 67 3.4E-21 T 23-10-2018 A3L01_07455 7e64cc00ef982433cfeae52449cbe0e1 90 Pfam PF04324 BFD-like [2Fe-2S] binding domain 6 58 2.7E-13 T 23-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A3L01_07365 246de2909c05b4f64c6ed67ff069bb4a 539 Gene3D G3DSA:1.20.1730.10 22 515 1.5E-92 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily A3L01_07365 246de2909c05b4f64c6ed67ff069bb4a 539 Pfam PF00474 Sodium:solute symporter family 33 435 1.3E-85 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A3L01_07365 246de2909c05b4f64c6ed67ff069bb4a 539 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 435 4.5E-79 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A3L01_04325 aef75edb8c590187ec7580fd90cbf77e 578 PIRSF PIRSF029254 1 575 2.6E-197 T 23-10-2018 IPR012401 DNA-binding protein MutS2, archaea A3L01_04325 aef75edb8c590187ec7580fd90cbf77e 578 Pfam PF00488 MutS domain V 389 471 6.9E-7 T 23-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A3L01_04325 aef75edb8c590187ec7580fd90cbf77e 578 SMART SM00534 386 578 1.1E-25 T 23-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A3L01_04325 aef75edb8c590187ec7580fd90cbf77e 578 SUPERFAMILY SSF52540 383 548 6.19E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_04325 aef75edb8c590187ec7580fd90cbf77e 578 Hamap MF_00971 DNA-binding protein MutS2 [mutS2]. 3 573 25.607 T 23-10-2018 IPR012401 DNA-binding protein MutS2, archaea A3L01_04325 aef75edb8c590187ec7580fd90cbf77e 578 Gene3D G3DSA:3.40.50.300 340 523 2.4E-21 T 23-10-2018 A3L01_00075 3e2316e21342dfa3a5dd55d9d3363d0e 104 Gene3D G3DSA:2.30.30.110 10 104 2.6E-22 T 23-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A3L01_00075 3e2316e21342dfa3a5dd55d9d3363d0e 104 SUPERFAMILY SSF50118 10 104 2.83E-19 T 23-10-2018 A3L01_00075 3e2316e21342dfa3a5dd55d9d3363d0e 104 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 12 101 5.8E-16 T 23-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 A3L01_09370 61bffb11621fd262290f73a355966f29 377 SUPERFAMILY SSF50156 204 293 2.23E-22 T 23-10-2018 IPR036034 PDZ superfamily GO:0005515 A3L01_09370 61bffb11621fd262290f73a355966f29 377 Pfam PF13180 PDZ domain 205 272 5.2E-14 T 23-10-2018 IPR001478 PDZ domain GO:0005515 A3L01_09370 61bffb11621fd262290f73a355966f29 377 SMART SM00228 190 263 7.7E-9 T 23-10-2018 IPR001478 PDZ domain GO:0005515 A3L01_09370 61bffb11621fd262290f73a355966f29 377 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 123 137 2.3E-22 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L01_09370 61bffb11621fd262290f73a355966f29 377 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 139 154 2.3E-22 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L01_09370 61bffb11621fd262290f73a355966f29 377 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 155 167 2.3E-22 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L01_09370 61bffb11621fd262290f73a355966f29 377 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 103 122 2.3E-22 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L01_09370 61bffb11621fd262290f73a355966f29 377 Pfam PF02163 Peptidase family M50 115 364 2.0E-21 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L01_09370 61bffb11621fd262290f73a355966f29 377 Gene3D G3DSA:2.30.42.10 203 291 7.1E-23 T 23-10-2018 A3L01_02170 40b6d11bfee298deaad1709a36e90901 216 PIRSF PIRSF002155 1 216 4.3E-68 T 23-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_02170 40b6d11bfee298deaad1709a36e90901 216 Gene3D G3DSA:3.40.50.790 59 150 2.4E-77 T 23-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich A3L01_02170 40b6d11bfee298deaad1709a36e90901 216 Gene3D G3DSA:3.30.190.20 13 213 2.4E-77 T 23-10-2018 A3L01_02170 40b6d11bfee298deaad1709a36e90901 216 SUPERFAMILY SSF56808 5 214 1.7E-65 T 23-10-2018 IPR023674 Ribosomal protein L1-like A3L01_02170 40b6d11bfee298deaad1709a36e90901 216 Pfam PF00687 Ribosomal protein L1p/L10e family 21 210 1.1E-48 T 23-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein A3L01_02170 40b6d11bfee298deaad1709a36e90901 216 ProSitePatterns PS01199 Ribosomal protein L1 signature. 114 133 - T 23-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_02170 40b6d11bfee298deaad1709a36e90901 216 Hamap MF_01318_A 50S ribosomal protein L1 [rplA]. 4 215 37.289 T 23-10-2018 IPR023669 Ribosomal protein L1, archaea GO:0003723|GO:0003735|GO:0006412|GO:0015934 A3L01_04185 f040e7aec771803b2a621fc325107217 233 Pfam PF02654 Cobalamin-5-phosphate synthase 5 221 9.0E-41 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A3L01_04185 f040e7aec771803b2a621fc325107217 233 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 233 30.072 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A3L01_04185 f040e7aec771803b2a621fc325107217 233 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 2 223 8.5E-47 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A3L01_08825 2c28521911d53074380171179fc8d669 235 SUPERFAMILY SSF55469 52 233 5.68E-37 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L01_08825 2c28521911d53074380171179fc8d669 235 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 73 231 3.5E-44 T 23-10-2018 IPR020051 SagB-type dehydrogenase domain A3L01_08825 2c28521911d53074380171179fc8d669 235 Gene3D G3DSA:3.40.109.10 25 233 4.9E-71 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L01_08825 2c28521911d53074380171179fc8d669 235 Pfam PF00881 Nitroreductase family 58 231 6.6E-34 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A3L01_04505 1b42172a471800a5d61ce1e5a0dd7fca 279 SUPERFAMILY SSF53335 20 277 7.23E-71 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_04505 1b42172a471800a5d61ce1e5a0dd7fca 279 Hamap MF_01922 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase [taw2]. 27 277 41.685 T 23-10-2018 IPR030867 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase GO:0006400|GO:0016765 MetaCyc: PWY-7286 A3L01_04505 1b42172a471800a5d61ce1e5a0dd7fca 279 Gene3D G3DSA:3.40.50.150 88 279 3.4E-59 T 23-10-2018 A3L01_04505 1b42172a471800a5d61ce1e5a0dd7fca 279 Gene3D G3DSA:3.30.300.110 20 87 8.0E-29 T 23-10-2018 A3L01_04505 1b42172a471800a5d61ce1e5a0dd7fca 279 Pfam PF02475 Met-10+ like-protein 30 224 8.9E-69 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A3L01_05285 963a17bc48bce137c4cb1af1b8e72cb8 158 Gene3D G3DSA:3.30.420.130 1 115 2.8E-31 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L01_05285 963a17bc48bce137c4cb1af1b8e72cb8 158 SUPERFAMILY SSF53146 1 112 1.57E-30 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L01_05285 963a17bc48bce137c4cb1af1b8e72cb8 158 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 106 8.9E-22 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A3L01_07785 7e5618360995e969c84d1ae0f36c2ed2 336 Pfam PF02475 Met-10+ like-protein 89 266 1.7E-36 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A3L01_07785 7e5618360995e969c84d1ae0f36c2ed2 336 Gene3D G3DSA:3.40.50.150 150 335 2.5E-34 T 23-10-2018 A3L01_07785 7e5618360995e969c84d1ae0f36c2ed2 336 Gene3D G3DSA:3.30.300.110 64 146 1.1E-11 T 23-10-2018 A3L01_07785 7e5618360995e969c84d1ae0f36c2ed2 336 SUPERFAMILY SSF53335 88 335 3.94E-46 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_09110 9a54cd37a326e31985c0163fb222d474 257 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 48 88 - T 23-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 A3L01_09110 9a54cd37a326e31985c0163fb222d474 257 SUPERFAMILY SSF53167 1 255 2.09E-92 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A3L01_09110 9a54cd37a326e31985c0163fb222d474 257 Pfam PF01048 Phosphorylase superfamily 3 237 3.0E-49 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A3L01_09110 9a54cd37a326e31985c0163fb222d474 257 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 4 238 9.3E-101 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A3L01_09110 9a54cd37a326e31985c0163fb222d474 257 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 257 45.23 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A3L01_09110 9a54cd37a326e31985c0163fb222d474 257 Gene3D G3DSA:3.40.50.1580 1 257 7.1E-103 T 23-10-2018 A3L01_05030 1475244973957a1e1874c6c0a364a857 125 Pfam PF01475 Ferric uptake regulator family 12 122 4.2E-21 T 23-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A3L01_05030 1475244973957a1e1874c6c0a364a857 125 Gene3D G3DSA:1.10.10.10 2 83 9.6E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_05030 1475244973957a1e1874c6c0a364a857 125 SUPERFAMILY SSF46785 4 112 4.76E-20 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_04475 e2548a64d689a1e37cfc1ecf629b5912 296 SUPERFAMILY SSF52540 93 280 4.1E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_04475 e2548a64d689a1e37cfc1ecf629b5912 296 Pfam PF03477 ATP cone domain 13 86 5.9E-10 T 23-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A3L01_04475 e2548a64d689a1e37cfc1ecf629b5912 296 Gene3D G3DSA:3.40.50.300 92 288 9.8E-11 T 23-10-2018 A3L01_04475 e2548a64d689a1e37cfc1ecf629b5912 296 Hamap MF_00769 2-phosphoglycerate kinase [pgk2]. 5 294 44.655 T 23-10-2018 IPR020872 2-phosphoglycerate kinase GO:0016774 A3L01_09050 5978736fb5b408c8174435e810bbf0e9 1299 TIGRFAM TIGR00354 polC: DNA polymerase II, large subunit DP2 10 1205 0.0 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L01_09050 5978736fb5b408c8174435e810bbf0e9 1299 Hamap MF_00324 DNA polymerase II large subunit [polC]. 1 1227 518.471 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L01_09050 5978736fb5b408c8174435e810bbf0e9 1299 Pfam PF03833 DNA polymerase II large subunit DP2 13 962 0.0 T 23-10-2018 IPR016033 DNA polymerase II large subunit DP2, N-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L01_09050 5978736fb5b408c8174435e810bbf0e9 1299 PIRSF PIRSF016275 3 1213 0.0 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L01_00455 961d38aa5f2f1a29344ec6d903d43292 138 Gene3D G3DSA:3.40.50.1010 7 136 3.5E-28 T 23-10-2018 A3L01_00455 961d38aa5f2f1a29344ec6d903d43292 138 Pfam PF04900 Fcf1 33 130 1.2E-6 T 23-10-2018 IPR006984 rRNA-processing protein Fcf1/Utp23 GO:0032040 A3L01_00455 961d38aa5f2f1a29344ec6d903d43292 138 SUPERFAMILY SSF88723 7 130 1.06E-23 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L01_00455 961d38aa5f2f1a29344ec6d903d43292 138 SMART SM00670 7 113 3.0E-6 T 23-10-2018 IPR002716 PIN domain A3L01_01215 cebf47e9bb079e3dabd9662b3ad64b45 261 Hamap MF_00320 DNA-directed RNA polymerase subunit D [rpoD]. 3 257 32.707 T 23-10-2018 IPR022842 DNA-directed RNA polymerase subunit D (Rpo3) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01215 cebf47e9bb079e3dabd9662b3ad64b45 261 Gene3D G3DSA:3.30.1360.10 7 251 4.4E-95 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01215 cebf47e9bb079e3dabd9662b3ad64b45 261 SUPERFAMILY SSF56553 39 149 2.75E-29 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01215 cebf47e9bb079e3dabd9662b3ad64b45 261 SUPERFAMILY SSF55257 3 257 6.47E-29 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01215 cebf47e9bb079e3dabd9662b3ad64b45 261 Gene3D G3DSA:2.170.120.12 40 147 4.4E-95 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01215 cebf47e9bb079e3dabd9662b3ad64b45 261 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 16 247 1.6E-18 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01215 cebf47e9bb079e3dabd9662b3ad64b45 261 SMART SM00662 14 254 1.2E-86 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01215 cebf47e9bb079e3dabd9662b3ad64b45 261 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 46 148 3.5E-28 T 23-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L01_01215 cebf47e9bb079e3dabd9662b3ad64b45 261 ProSitePatterns PS00446 RNA polymerases D / 30 to 40 Kd subunits signature. 28 68 - T 23-10-2018 IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 A3L01_01215 cebf47e9bb079e3dabd9662b3ad64b45 261 Gene3D G3DSA:3.30.70.3110 157 218 4.4E-95 T 23-10-2018 A3L01_00550 ef92d21a6e875f08e3a726bbb9299118 445 PIRSF PIRSF005353 1 442 1.1E-166 T 23-10-2018 IPR026033 Purine permease PbuG-like A3L01_00550 ef92d21a6e875f08e3a726bbb9299118 445 Pfam PF00860 Permease family 20 401 3.9E-45 T 23-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A3L01_01045 faa098a63b84c8472e9ac9d2a7aa3320 239 Gene3D G3DSA:4.10.950.10 163 239 3.4E-34 T 23-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01045 faa098a63b84c8472e9ac9d2a7aa3320 239 Gene3D G3DSA:2.30.30.30 85 162 1.3E-29 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L01_01045 faa098a63b84c8472e9ac9d2a7aa3320 239 SMART SM01383 11 85 5.1E-26 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01045 faa098a63b84c8472e9ac9d2a7aa3320 239 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 11 84 4.1E-21 T 23-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01045 faa098a63b84c8472e9ac9d2a7aa3320 239 SMART SM01382 91 223 3.1E-61 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A3L01_01045 faa098a63b84c8472e9ac9d2a7aa3320 239 Gene3D G3DSA:2.40.50.140 1 81 1.6E-31 T 23-10-2018 A3L01_01045 faa098a63b84c8472e9ac9d2a7aa3320 239 PIRSF PIRSF002158 1 239 2.9E-73 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01045 faa098a63b84c8472e9ac9d2a7aa3320 239 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 92 222 4.4E-42 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A3L01_01045 faa098a63b84c8472e9ac9d2a7aa3320 239 SUPERFAMILY SSF50249 2 93 3.77E-24 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_01045 faa098a63b84c8472e9ac9d2a7aa3320 239 SUPERFAMILY SSF50104 94 237 1.87E-47 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L01_01045 faa098a63b84c8472e9ac9d2a7aa3320 239 Hamap MF_01320_A 50S ribosomal protein L2 [rplB]. 1 238 42.249 T 23-10-2018 IPR023672 Ribosomal protein L2, archaeal-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_02735 f36cf969553c7dc58c5a5f7d2441fd93 206 Pfam PF04919 Protein of unknown function (DUF655) 23 198 7.1E-68 T 23-10-2018 IPR007003 Protein of unknown function DUF655 A3L01_02735 f36cf969553c7dc58c5a5f7d2441fd93 206 Gene3D G3DSA:2.40.50.140 23 92 2.2E-22 T 23-10-2018 A3L01_02735 f36cf969553c7dc58c5a5f7d2441fd93 206 Gene3D G3DSA:1.10.150.280 93 190 4.0E-42 T 23-10-2018 A3L01_02735 f36cf969553c7dc58c5a5f7d2441fd93 206 SUPERFAMILY SSF160975 23 199 3.79E-91 T 23-10-2018 A3L01_08635 0b6880fc067098d974e6d39297db902f 538 SUPERFAMILY SSF56300 309 512 7.6E-32 T 23-10-2018 A3L01_08635 0b6880fc067098d974e6d39297db902f 538 Pfam PF00149 Calcineurin-like phosphoesterase 309 486 4.7E-10 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L01_08635 0b6880fc067098d974e6d39297db902f 538 Gene3D G3DSA:3.60.21.10 305 518 6.9E-17 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L01_08965 2dae4a4b6aa89a5500864df2b2e75243 172 Pfam PF11447 Protein of unknown function (DUF3201) 8 158 4.8E-66 T 23-10-2018 IPR024505 Protein of unknown function DUF3201 A3L01_08965 2dae4a4b6aa89a5500864df2b2e75243 172 SUPERFAMILY SSF142913 3 170 1.05E-51 T 23-10-2018 A3L01_08965 2dae4a4b6aa89a5500864df2b2e75243 172 Gene3D G3DSA:3.30.930.10 1 170 2.8E-64 T 23-10-2018 A3L01_04585 b670e3e5acb126ad1e503e31e0b92717 361 Pfam PF01966 HD domain 50 132 1.6E-10 T 23-10-2018 IPR006674 HD domain A3L01_04585 b670e3e5acb126ad1e503e31e0b92717 361 Gene3D G3DSA:1.10.3210.10 1 255 4.9E-72 T 23-10-2018 A3L01_04585 b670e3e5acb126ad1e503e31e0b92717 361 SUPERFAMILY SSF109604 1 347 3.29E-81 T 23-10-2018 A3L01_04585 b670e3e5acb126ad1e503e31e0b92717 361 SMART SM00471 46 156 4.9E-15 T 23-10-2018 IPR003607 HD/PDEase domain A3L01_07105 6fabd3ce75a9e7448b9ea61418b7bb9a 133 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 6 120 2.9E-25 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A3L01_09745 372e3c0e5ac2ab612b3919c0f3b0ea88 255 Gene3D G3DSA:3.30.70.1450 133 230 1.9E-14 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L01_09745 372e3c0e5ac2ab612b3919c0f3b0ea88 255 Pfam PF02080 TrkA-C domain 156 225 2.1E-11 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A3L01_09745 372e3c0e5ac2ab612b3919c0f3b0ea88 255 SUPERFAMILY SSF116726 144 226 3.4E-13 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L01_01935 76caf095d0eb8849ecc7d31dfb1d2a61 147 SUPERFAMILY SSF50249 23 147 4.88E-37 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_01935 76caf095d0eb8849ecc7d31dfb1d2a61 147 Hamap MF_00403_A 30S ribosomal protein S12 [rpsL]. 1 147 44.994 T 23-10-2018 IPR022863 Ribosomal protein S12, archaea A3L01_01935 76caf095d0eb8849ecc7d31dfb1d2a61 147 PRINTS PR01034 Ribosomal protein S12 signature 47 62 9.7E-5 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01935 76caf095d0eb8849ecc7d31dfb1d2a61 147 PRINTS PR01034 Ribosomal protein S12 signature 79 98 9.7E-5 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01935 76caf095d0eb8849ecc7d31dfb1d2a61 147 PRINTS PR01034 Ribosomal protein S12 signature 62 77 9.7E-5 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01935 76caf095d0eb8849ecc7d31dfb1d2a61 147 TIGRFAM TIGR00982 uS12_E_A: ribosomal protein uS12 9 147 1.1E-81 T 23-10-2018 IPR005680 Ribosomal protein S23, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01935 76caf095d0eb8849ecc7d31dfb1d2a61 147 Pfam PF00164 Ribosomal protein S12/S23 32 146 7.5E-51 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01935 76caf095d0eb8849ecc7d31dfb1d2a61 147 Gene3D G3DSA:2.40.50.140 28 147 1.1E-51 T 23-10-2018 A3L01_01935 76caf095d0eb8849ecc7d31dfb1d2a61 147 ProSitePatterns PS00055 Ribosomal protein S12 signature. 63 70 - T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01935 76caf095d0eb8849ecc7d31dfb1d2a61 147 PIRSF PIRSF002133 19 147 2.2E-37 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_06485 948b6d7b518e34d559eb6c685f031a4b 259 Gene3D G3DSA:2.40.30.90 161 256 1.7E-35 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal A3L01_06485 948b6d7b518e34d559eb6c685f031a4b 259 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 2 252 2.1E-76 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase A3L01_06485 948b6d7b518e34d559eb6c685f031a4b 259 SUPERFAMILY SSF101852 163 254 6.41E-26 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal A3L01_06485 948b6d7b518e34d559eb6c685f031a4b 259 SUPERFAMILY SSF102522 1 161 1.31E-54 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal A3L01_06485 948b6d7b518e34d559eb6c685f031a4b 259 Gene3D G3DSA:3.40.50.10790 1 160 2.5E-59 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal A3L01_06485 948b6d7b518e34d559eb6c685f031a4b 259 PIRSF PIRSF006779 1 256 1.3E-76 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase A3L01_07315 f385a5bee15d004c52704652e38d1457 308 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 9 286 2.8E-50 T 23-10-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 A3L01_07315 f385a5bee15d004c52704652e38d1457 308 Gene3D G3DSA:1.10.4200.10 25 293 4.1E-59 T 23-10-2018 A3L01_05765 941c51f16d51bf39ac7d0185f6a7670d 143 SUPERFAMILY SSF54585 2 74 2.68E-11 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily A3L01_05765 941c51f16d51bf39ac7d0185f6a7670d 143 Gene3D G3DSA:3.10.330.10 1 77 3.0E-27 T 23-10-2018 A3L01_05765 941c51f16d51bf39ac7d0185f6a7670d 143 Gene3D G3DSA:2.40.10.360 81 143 1.2E-11 T 23-10-2018 A3L01_05765 941c51f16d51bf39ac7d0185f6a7670d 143 SMART SM01072 12 74 1.2E-6 T 23-10-2018 IPR004201 CDC48, domain 2 A3L01_05765 941c51f16d51bf39ac7d0185f6a7670d 143 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 13 70 5.8E-6 T 23-10-2018 IPR004201 CDC48, domain 2 A3L01_08480 cd3c52a75df6ea94bb50bfaddde8f7b5 115 Pfam PF03788 LrgA family 15 106 5.3E-28 T 23-10-2018 IPR005538 LrgA/CidA family GO:0016021 A3L01_09250 bebe29614dd7dc097fd0209d366f2b93 621 Gene3D G3DSA:3.40.50.300 322 609 7.3E-102 T 23-10-2018 A3L01_09250 bebe29614dd7dc097fd0209d366f2b93 621 SUPERFAMILY SSF52540 207 531 6.39E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_09250 bebe29614dd7dc097fd0209d366f2b93 621 Gene3D G3DSA:3.30.450.380 104 321 7.4E-67 T 23-10-2018 A3L01_09250 bebe29614dd7dc097fd0209d366f2b93 621 SMART SM00382 354 519 0.0018 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_09250 bebe29614dd7dc097fd0209d366f2b93 621 Pfam PF00437 Type II/IV secretion system protein 227 484 1.3E-64 T 23-10-2018 IPR001482 Type II/IV secretion system protein A3L01_09030 5aab01fbe70c25bae5a8299d52333b02 1682 SMART SM00487 150 410 5.8E-16 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L01_09030 5aab01fbe70c25bae5a8299d52333b02 1682 SUPERFAMILY SSF52540 162 592 4.1E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_09030 5aab01fbe70c25bae5a8299d52333b02 1682 SMART SM00490 514 590 1.3E-15 T 23-10-2018 IPR001650 Helicase, C-terminal A3L01_09030 5aab01fbe70c25bae5a8299d52333b02 1682 Gene3D G3DSA:3.30.870.10 1563 1679 5.1E-7 T 23-10-2018 A3L01_09030 5aab01fbe70c25bae5a8299d52333b02 1682 Pfam PF00270 DEAD/DEAH box helicase 155 277 4.5E-10 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L01_09030 5aab01fbe70c25bae5a8299d52333b02 1682 Pfam PF00271 Helicase conserved C-terminal domain 450 588 1.5E-12 T 23-10-2018 IPR001650 Helicase, C-terminal A3L01_00585 a2339aa01c8a58b485be23e7d3a2c009 374 Pfam PF04123 Domain of unknown function (DUF373) 3 345 1.0E-96 T 23-10-2018 IPR007254 Protein of unknown function DUF373 A3L01_05950 d2cc2f48c80467948ace7080ea3df071 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 197 221 2.3E-25 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L01_05950 d2cc2f48c80467948ace7080ea3df071 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 164 185 2.3E-25 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L01_05950 d2cc2f48c80467948ace7080ea3df071 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 2.3E-25 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L01_05950 d2cc2f48c80467948ace7080ea3df071 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 80 96 2.3E-25 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L01_05950 d2cc2f48c80467948ace7080ea3df071 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 129 152 2.3E-25 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L01_05950 d2cc2f48c80467948ace7080ea3df071 256 SUPERFAMILY SSF56655 6 248 1.06E-55 T 23-10-2018 A3L01_05950 d2cc2f48c80467948ace7080ea3df071 256 Pfam PF00459 Inositol monophosphatase family 7 253 2.4E-33 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L01_05950 d2cc2f48c80467948ace7080ea3df071 256 Gene3D G3DSA:3.40.190.80 143 254 6.8E-26 T 23-10-2018 A3L01_05950 d2cc2f48c80467948ace7080ea3df071 256 Gene3D G3DSA:3.30.540.10 3 139 4.2E-37 T 23-10-2018 A3L01_05840 aaaa7fef1f7941af7e6872629d18191d 216 SUPERFAMILY SSF81301 12 71 1.58E-5 T 23-10-2018 A3L01_05840 aaaa7fef1f7941af7e6872629d18191d 216 Gene3D G3DSA:3.30.460.10 9 97 9.0E-6 T 23-10-2018 A3L01_08645 c135ff06352e70a48702e3a1fed39445 189 Gene3D G3DSA:2.10.109.10 27 136 1.7E-5 T 23-10-2018 A3L01_08645 c135ff06352e70a48702e3a1fed39445 189 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 98 109 7.2E-5 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L01_08645 c135ff06352e70a48702e3a1fed39445 189 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 37 52 7.2E-5 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L01_08645 c135ff06352e70a48702e3a1fed39445 189 Pfam PF00717 Peptidase S24-like 37 91 6.2E-7 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A3L01_08645 c135ff06352e70a48702e3a1fed39445 189 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 7 148 5.4E-24 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L01_08645 c135ff06352e70a48702e3a1fed39445 189 SUPERFAMILY SSF51306 29 127 7.06E-12 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A3L01_07120 27bff87b7b7d0cd5729df4b757144d68 135 Gene3D G3DSA:3.30.70.260 47 131 9.7E-11 T 23-10-2018 A3L01_07120 27bff87b7b7d0cd5729df4b757144d68 135 SUPERFAMILY SSF55021 60 130 3.05E-12 T 23-10-2018 A3L01_07120 27bff87b7b7d0cd5729df4b757144d68 135 Pfam PF01842 ACT domain 59 119 6.0E-11 T 23-10-2018 IPR002912 ACT domain A3L01_01500 5d29bbfe7a7a268d3afac246a1cc2dd6 138 SUPERFAMILY SSF47598 2 49 7.41E-14 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A3L01_01500 5d29bbfe7a7a268d3afac246a1cc2dd6 138 Pfam PF08753 NikR C terminal nickel binding domain 55 131 4.5E-34 T 23-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal A3L01_01500 5d29bbfe7a7a268d3afac246a1cc2dd6 138 Pfam PF01402 Ribbon-helix-helix protein, copG family 5 42 1.8E-8 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A3L01_01500 5d29bbfe7a7a268d3afac246a1cc2dd6 138 SUPERFAMILY SSF55021 53 133 3.89E-29 T 23-10-2018 A3L01_01500 5d29bbfe7a7a268d3afac246a1cc2dd6 138 Gene3D G3DSA:3.30.70.1150 51 138 8.1E-38 T 23-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal A3L01_01500 5d29bbfe7a7a268d3afac246a1cc2dd6 138 Gene3D G3DSA:1.10.1220.10 10 50 2.0E-21 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A3L01_01500 5d29bbfe7a7a268d3afac246a1cc2dd6 138 Hamap MF_00476 Nickel-responsive regulator [nikR]. 3 133 30.918 T 23-10-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 A3L01_08310 f797a9a254921dc1e03f2c2e33463f83 275 SUPERFAMILY SSF103481 178 272 1.96E-6 T 23-10-2018 A3L01_08310 f797a9a254921dc1e03f2c2e33463f83 275 Pfam PF00892 EamA-like transporter family 6 130 4.4E-20 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L01_08310 f797a9a254921dc1e03f2c2e33463f83 275 Pfam PF00892 EamA-like transporter family 144 272 8.1E-13 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L01_08310 f797a9a254921dc1e03f2c2e33463f83 275 SUPERFAMILY SSF103481 38 133 1.19E-16 T 23-10-2018 A3L01_07465 2c644b70aee522fb1077c3cf96b66a1f 168 SUPERFAMILY SSF54862 27 137 2.8E-18 T 23-10-2018 A3L01_07465 2c644b70aee522fb1077c3cf96b66a1f 168 Pfam PF00037 4Fe-4S binding domain 67 88 2.3E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_07465 2c644b70aee522fb1077c3cf96b66a1f 168 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 74 85 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_07465 2c644b70aee522fb1077c3cf96b66a1f 168 Gene3D G3DSA:3.30.70.20 36 106 2.9E-12 T 23-10-2018 A3L01_06320 0019f9ef420d3ebf5429037dbc6a9bc2 562 Gene3D G3DSA:3.20.20.240 1 562 7.4E-270 T 23-10-2018 A3L01_06320 0019f9ef420d3ebf5429037dbc6a9bc2 562 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 37 560 1.2E-290 T 23-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L01_06320 0019f9ef420d3ebf5429037dbc6a9bc2 562 Pfam PF01642 Methylmalonyl-CoA mutase 39 554 2.2E-241 T 23-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L01_06320 0019f9ef420d3ebf5429037dbc6a9bc2 562 SUPERFAMILY SSF51703 9 556 6.28E-231 T 23-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L01_02990 83394a17d3d0553ed2f4cbfc35987f31 213 Hamap MF_00699 Probable Brix domain-containing ribosomal biogenesis protein. 2 191 29.396 T 23-10-2018 IPR023548 Probable Brix domain-containing ribosomal biogenesis protein A3L01_02990 83394a17d3d0553ed2f4cbfc35987f31 213 SMART SM00879 3 190 9.5E-16 T 23-10-2018 IPR007109 Brix domain A3L01_02990 83394a17d3d0553ed2f4cbfc35987f31 213 SUPERFAMILY SSF52954 1 193 8.83E-35 T 23-10-2018 A3L01_02990 83394a17d3d0553ed2f4cbfc35987f31 213 Gene3D G3DSA:3.40.50.10480 1 186 1.3E-32 T 23-10-2018 A3L01_01620 ad0b2d9ee974c5daf7bf8d8a771b1c44 388 Pfam PF04981 NMD3 family 6 276 2.7E-62 T 23-10-2018 IPR007064 Nmd3, N-terminal A3L01_01620 ad0b2d9ee974c5daf7bf8d8a771b1c44 388 Gene3D G3DSA:2.40.50.140 332 384 7.4E-8 T 23-10-2018 A3L01_01620 ad0b2d9ee974c5daf7bf8d8a771b1c44 388 SUPERFAMILY SSF50249 332 382 6.0E-5 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_05255 4e074512c6c8127c1d85fb67de34065b 177 Pfam PF10007 Uncharacterized protein conserved in archaea (DUF2250) 18 105 2.9E-32 T 23-10-2018 IPR019254 Protein of unknown function DUF2250 A3L01_09900 73a5a74c29a0bcc0b8440f949d6d3fce 233 Gene3D G3DSA:2.40.30.10 3 83 1.3E-10 T 23-10-2018 A3L01_09900 73a5a74c29a0bcc0b8440f949d6d3fce 233 PIRSF PIRSF006816 1 232 2.0E-71 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L01_09900 73a5a74c29a0bcc0b8440f949d6d3fce 233 SUPERFAMILY SSF63380 4 85 1.24E-16 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L01_09900 73a5a74c29a0bcc0b8440f949d6d3fce 233 SUPERFAMILY SSF52343 80 228 1.06E-31 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L01_09900 73a5a74c29a0bcc0b8440f949d6d3fce 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 93 112 4.9E-5 T 23-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A3L01_09900 73a5a74c29a0bcc0b8440f949d6d3fce 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 170 178 4.9E-5 T 23-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A3L01_09900 73a5a74c29a0bcc0b8440f949d6d3fce 233 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 2 231 32.942 T 23-10-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit A3L01_09900 73a5a74c29a0bcc0b8440f949d6d3fce 233 Pfam PF00175 Oxidoreductase NAD-binding domain 94 183 1.9E-5 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A3L01_09900 73a5a74c29a0bcc0b8440f949d6d3fce 233 Gene3D G3DSA:3.40.50.80 86 196 1.2E-25 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L01_09900 73a5a74c29a0bcc0b8440f949d6d3fce 233 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 197 229 9.4E-11 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L01_07230 b9e1ac26f8803653c362db88ebb40e8e 284 SUPERFAMILY SSF103481 39 141 1.83E-8 T 23-10-2018 A3L01_07230 b9e1ac26f8803653c362db88ebb40e8e 284 SUPERFAMILY SSF103481 189 283 3.79E-14 T 23-10-2018 A3L01_07230 b9e1ac26f8803653c362db88ebb40e8e 284 Pfam PF00892 EamA-like transporter family 148 283 5.3E-22 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L01_07230 b9e1ac26f8803653c362db88ebb40e8e 284 Pfam PF00892 EamA-like transporter family 5 136 2.8E-20 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L01_07090 d7f3cb157924d623bbbf636fe4d96447 104 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 6 99 9.5E-29 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L01_07090 d7f3cb157924d623bbbf636fe4d96447 104 Pfam PF03334 Na+/H+ antiporter subunit 6 86 2.5E-22 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L01_08215 e936bf0ba055a71403dee15b012af5e8 153 Gene3D G3DSA:3.40.50.1450 9 152 2.3E-20 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L01_08215 e936bf0ba055a71403dee15b012af5e8 153 SUPERFAMILY SSF53163 12 145 1.52E-13 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L01_02325 a3d1f9d23dcb6eedb79dd27972c00760 232 SUPERFAMILY SSF56059 23 232 5.13E-51 T 23-10-2018 A3L01_02325 a3d1f9d23dcb6eedb79dd27972c00760 232 Gene3D G3DSA:3.30.1490.20 39 116 3.1E-91 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L01_02325 a3d1f9d23dcb6eedb79dd27972c00760 232 Gene3D G3DSA:3.30.470.20 21 230 3.1E-91 T 23-10-2018 A3L01_02325 a3d1f9d23dcb6eedb79dd27972c00760 232 Pfam PF13549 ATP-grasp domain 16 231 5.4E-84 T 23-10-2018 A3L01_08930 fe21621ece5e44b97c3dc624a66420c0 232 SUPERFAMILY SSF69572 2 230 5.49E-80 T 23-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 A3L01_08930 fe21621ece5e44b97c3dc624a66420c0 232 Pfam PF00899 ThiF family 10 231 6.1E-57 T 23-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A3L01_08930 fe21621ece5e44b97c3dc624a66420c0 232 Gene3D G3DSA:3.40.50.720 2 232 3.7E-73 T 23-10-2018 A3L01_00820 fca28fc5823329ba95ff65631e3a7e24 207 TIGRFAM TIGR00310 ZPR1_znf: ZPR1 zinc finger domain 15 193 4.7E-63 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 A3L01_00820 fca28fc5823329ba95ff65631e3a7e24 207 TIGRFAM TIGR00340 zpr1_rel: zinc finger protein ZPR1 homolog 16 181 7.1E-69 T 23-10-2018 IPR004470 Zinc finger, ZPR1-type, subgroup GO:0008270 A3L01_00820 fca28fc5823329ba95ff65631e3a7e24 207 Gene3D G3DSA:2.20.25.420 3 59 2.5E-7 T 23-10-2018 A3L01_00820 fca28fc5823329ba95ff65631e3a7e24 207 Pfam PF03367 ZPR1 zinc-finger domain 15 171 1.0E-38 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 A3L01_00820 fca28fc5823329ba95ff65631e3a7e24 207 SMART SM00709 14 174 3.1E-76 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 A3L01_00820 fca28fc5823329ba95ff65631e3a7e24 207 Gene3D G3DSA:2.60.120.1040 63 188 8.8E-22 T 23-10-2018 A3L01_05090 803898eee02ea07b03d8669b22749ae1 377 Pfam PF00815 Histidinol dehydrogenase 256 376 3.0E-39 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L01_05090 803898eee02ea07b03d8669b22749ae1 377 Pfam PF00815 Histidinol dehydrogenase 5 248 8.0E-91 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L01_05090 803898eee02ea07b03d8669b22749ae1 377 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 9 249 4.6E-92 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L01_05090 803898eee02ea07b03d8669b22749ae1 377 Gene3D G3DSA:3.40.50.1980 2 213 1.9E-69 T 23-10-2018 A3L01_05090 803898eee02ea07b03d8669b22749ae1 377 PRINTS PR00083 Histidinol dehydrogenase signature 221 240 2.8E-95 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L01_05090 803898eee02ea07b03d8669b22749ae1 377 PRINTS PR00083 Histidinol dehydrogenase signature 311 329 2.8E-95 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L01_05090 803898eee02ea07b03d8669b22749ae1 377 PRINTS PR00083 Histidinol dehydrogenase signature 170 195 2.8E-95 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L01_05090 803898eee02ea07b03d8669b22749ae1 377 PRINTS PR00083 Histidinol dehydrogenase signature 199 220 2.8E-95 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L01_05090 803898eee02ea07b03d8669b22749ae1 377 PRINTS PR00083 Histidinol dehydrogenase signature 270 295 2.8E-95 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L01_05090 803898eee02ea07b03d8669b22749ae1 377 PRINTS PR00083 Histidinol dehydrogenase signature 9 33 2.8E-95 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L01_05090 803898eee02ea07b03d8669b22749ae1 377 PRINTS PR00083 Histidinol dehydrogenase signature 141 167 2.8E-95 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L01_05090 803898eee02ea07b03d8669b22749ae1 377 PRINTS PR00083 Histidinol dehydrogenase signature 107 133 2.8E-95 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L01_05090 803898eee02ea07b03d8669b22749ae1 377 PRINTS PR00083 Histidinol dehydrogenase signature 80 107 2.8E-95 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L01_05090 803898eee02ea07b03d8669b22749ae1 377 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 377 36.421 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L01_05090 803898eee02ea07b03d8669b22749ae1 377 SUPERFAMILY SSF53720 8 376 1.29E-56 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A3L01_05090 803898eee02ea07b03d8669b22749ae1 377 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 199 231 - T 23-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 A3L01_05090 803898eee02ea07b03d8669b22749ae1 377 Gene3D G3DSA:3.40.50.1980 250 321 4.2E-20 T 23-10-2018 A3L01_04005 f0af8f8a97e54e53824fdca15e06e68a 222 Gene3D G3DSA:3.40.50.1000 5 134 1.8E-9 T 23-10-2018 IPR023214 HAD superfamily A3L01_04005 f0af8f8a97e54e53824fdca15e06e68a 222 SUPERFAMILY SSF56784 3 187 1.87E-14 T 23-10-2018 IPR036412 HAD-like superfamily A3L01_04005 f0af8f8a97e54e53824fdca15e06e68a 222 Gene3D G3DSA:1.10.150.520 15 84 1.8E-9 T 23-10-2018 A3L01_04005 f0af8f8a97e54e53824fdca15e06e68a 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 101 9.4E-6 T 23-10-2018 A3L01_09860 124b37a0f6fe297f68915ef31a8599b2 407 Gene3D G3DSA:3.10.310.40 302 406 1.5E-9 T 23-10-2018 A3L01_09860 124b37a0f6fe297f68915ef31a8599b2 407 SMART SM00863 191 234 6.3E-14 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L01_09860 124b37a0f6fe297f68915ef31a8599b2 407 Gene3D G3DSA:2.40.30.130 1 79 5.0E-19 T 23-10-2018 A3L01_09860 124b37a0f6fe297f68915ef31a8599b2 407 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 191 234 2.1E-10 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L01_09860 124b37a0f6fe297f68915ef31a8599b2 407 SUPERFAMILY SSF55186 92 238 1.7E-34 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A3L01_09860 124b37a0f6fe297f68915ef31a8599b2 407 Pfam PF01411 tRNA synthetases class II (A) 17 94 2.7E-11 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A3L01_09860 124b37a0f6fe297f68915ef31a8599b2 407 Gene3D G3DSA:3.30.980.10 92 247 4.4E-39 T 23-10-2018 A3L01_09860 124b37a0f6fe297f68915ef31a8599b2 407 Pfam PF02272 DHHA1 domain 272 401 2.8E-12 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L01_09860 124b37a0f6fe297f68915ef31a8599b2 407 SUPERFAMILY SSF50447 1 89 1.59E-14 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L01_07220 6265b55bff1e4755abfc809c023e3bd3 169 Pfam PF00583 Acetyltransferase (GNAT) family 41 141 7.7E-18 T 23-10-2018 IPR000182 GNAT domain A3L01_07220 6265b55bff1e4755abfc809c023e3bd3 169 Gene3D G3DSA:3.40.630.30 1 159 2.4E-49 T 23-10-2018 A3L01_07220 6265b55bff1e4755abfc809c023e3bd3 169 SUPERFAMILY SSF55729 1 154 8.61E-30 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L01_04045 32f6e09a3e21188ba538ad706cb2ed68 84 Pfam PF09012 FeoC like transcriptional regulator 14 58 3.9E-6 T 23-10-2018 IPR015102 Transcriptional regulator HTH-type, FeoC A3L01_04045 32f6e09a3e21188ba538ad706cb2ed68 84 Gene3D G3DSA:1.10.10.10 2 55 2.0E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_04045 32f6e09a3e21188ba538ad706cb2ed68 84 SUPERFAMILY SSF46785 2 64 8.33E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_08830 82debc33152b273e7734e5ab5d4e948d 161 Pfam PF02926 THUMP domain 33 148 5.2E-20 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L01_08830 82debc33152b273e7734e5ab5d4e948d 161 SUPERFAMILY SSF143437 47 147 1.01E-14 T 23-10-2018 A3L01_08830 82debc33152b273e7734e5ab5d4e948d 161 Gene3D G3DSA:3.30.2130.30 1 151 1.5E-12 T 23-10-2018 A3L01_08830 82debc33152b273e7734e5ab5d4e948d 161 SMART SM00981 63 150 1.0E-13 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L01_08920 7dd4611742ac4613ef9ef919cd8c42d6 142 Pfam PF02391 MoaE protein 5 117 3.9E-36 T 23-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A3L01_08920 7dd4611742ac4613ef9ef919cd8c42d6 142 Gene3D G3DSA:3.90.1170.40 1 136 1.2E-48 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A3L01_08920 7dd4611742ac4613ef9ef919cd8c42d6 142 SUPERFAMILY SSF54690 3 136 3.27E-45 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A3L01_09435 c74d0fbb3d895b5a62164da03f9158f6 379 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 26 376 50.528 T 23-10-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A3L01_09435 c74d0fbb3d895b5a62164da03f9158f6 379 SUPERFAMILY SSF52374 164 372 2.25E-78 T 23-10-2018 A3L01_09435 c74d0fbb3d895b5a62164da03f9158f6 379 SUPERFAMILY SSF88697 4 161 4.28E-48 T 23-10-2018 IPR015947 PUA-like superfamily A3L01_09435 c74d0fbb3d895b5a62164da03f9158f6 379 Gene3D G3DSA:3.40.50.620 164 373 2.8E-90 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_09435 c74d0fbb3d895b5a62164da03f9158f6 379 Gene3D G3DSA:3.10.400.10 1 159 5.7E-47 T 23-10-2018 A3L01_09435 c74d0fbb3d895b5a62164da03f9158f6 379 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 5 371 4.3E-120 T 23-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A3L01_09435 c74d0fbb3d895b5a62164da03f9158f6 379 Pfam PF01747 ATP-sulfurylase 164 372 8.6E-87 T 23-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A3L01_09435 c74d0fbb3d895b5a62164da03f9158f6 379 Pfam PF14306 PUA-like domain 4 156 5.8E-50 T 23-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A3L01_06670 26b39c225e1401741d10d520dbcf7b89 439 Gene3D G3DSA:3.40.1480.10 269 432 4.4E-162 T 23-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily A3L01_06670 26b39c225e1401741d10d520dbcf7b89 439 Pfam PF13660 Domain of unknown function (DUF4147) 7 243 2.0E-80 T 23-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 A3L01_06670 26b39c225e1401741d10d520dbcf7b89 439 SUPERFAMILY SSF82544 2 435 1.44E-134 T 23-10-2018 A3L01_06670 26b39c225e1401741d10d520dbcf7b89 439 Gene3D G3DSA:3.40.50.10180 23 268 4.4E-162 T 23-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 A3L01_06670 26b39c225e1401741d10d520dbcf7b89 439 Pfam PF05161 MOFRL family 325 428 1.1E-33 T 23-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 A3L01_09360 789e8422ec419be74f6536f9a3820240 323 PIRSF PIRSF004976 1 317 2.1E-110 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 A3L01_09360 789e8422ec419be74f6536f9a3820240 323 SUPERFAMILY SSF52402 36 270 1.32E-53 T 23-10-2018 A3L01_09360 789e8422ec419be74f6536f9a3820240 323 Gene3D G3DSA:3.40.50.620 1 318 4.7E-86 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_09360 789e8422ec419be74f6536f9a3820240 323 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 204 305 5.7E-37 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 A3L01_09360 789e8422ec419be74f6536f9a3820240 323 Pfam PF01171 PP-loop family 50 228 9.7E-14 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A3L01_02610 9ae37fcfa3cd5d219a0956b6af63ddd8 268 SUPERFAMILY SSF51658 1 237 3.4E-27 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily A3L01_02610 9ae37fcfa3cd5d219a0956b6af63ddd8 268 Gene3D G3DSA:3.20.20.150 1 255 4.0E-26 T 23-10-2018 A3L01_02610 9ae37fcfa3cd5d219a0956b6af63ddd8 268 Pfam PF01261 Xylose isomerase-like TIM barrel 30 228 1.7E-15 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A3L01_00120 6ad9f3596200764804c2b6e2ad68b7f3 223 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 220 6.5E-50 T 23-10-2018 A3L01_00120 6ad9f3596200764804c2b6e2ad68b7f3 223 Gene3D G3DSA:3.40.50.880 1 223 5.4E-78 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_00120 6ad9f3596200764804c2b6e2ad68b7f3 223 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 2 220 1.0E-94 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L01_00120 6ad9f3596200764804c2b6e2ad68b7f3 223 SMART SM01211 1 221 4.7E-132 T 23-10-2018 A3L01_00120 6ad9f3596200764804c2b6e2ad68b7f3 223 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 2 219 44.633 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L01_00120 6ad9f3596200764804c2b6e2ad68b7f3 223 PIRSF PIRSF001586 1 223 7.1E-83 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L01_00120 6ad9f3596200764804c2b6e2ad68b7f3 223 SUPERFAMILY SSF52317 3 221 1.53E-77 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_05680 20282694ba1f592df1e2481c8fce28ff 157 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 23-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A3L01_05680 20282694ba1f592df1e2481c8fce28ff 157 SMART SM00344 4 112 1.6E-30 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L01_05680 20282694ba1f592df1e2481c8fce28ff 157 Gene3D G3DSA:3.30.70.920 56 149 1.7E-11 T 23-10-2018 A3L01_05680 20282694ba1f592df1e2481c8fce28ff 157 SUPERFAMILY SSF46785 4 62 2.12E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_05680 20282694ba1f592df1e2481c8fce28ff 157 Pfam PF13404 AsnC-type helix-turn-helix domain 5 45 1.1E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_05680 20282694ba1f592df1e2481c8fce28ff 157 SUPERFAMILY SSF54909 66 149 3.49E-7 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L01_05680 20282694ba1f592df1e2481c8fce28ff 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 7.9E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_05680 20282694ba1f592df1e2481c8fce28ff 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 7.9E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_05680 20282694ba1f592df1e2481c8fce28ff 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 7.9E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_05680 20282694ba1f592df1e2481c8fce28ff 157 Gene3D G3DSA:1.10.10.10 2 55 3.3E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_03150 fa955176c4e68f85a32bc08401d8509f 248 Pfam PF12838 4Fe-4S dicluster domain 63 117 5.4E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_03150 fa955176c4e68f85a32bc08401d8509f 248 SUPERFAMILY SSF54862 25 125 3.03E-22 T 23-10-2018 A3L01_03150 fa955176c4e68f85a32bc08401d8509f 248 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 103 114 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_03150 fa955176c4e68f85a32bc08401d8509f 248 Gene3D G3DSA:3.30.70.3270 42 174 1.1E-23 T 23-10-2018 A3L01_04370 94ce0123fb5fe1dd22fe721fb241308a 142 Hamap MF_01222 Protein archease. 2 142 40.394 T 23-10-2018 IPR022952 Archease, archaea A3L01_04370 94ce0123fb5fe1dd22fe721fb241308a 142 SUPERFAMILY SSF69819 2 142 1.11E-47 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 A3L01_04370 94ce0123fb5fe1dd22fe721fb241308a 142 Pfam PF01951 Archease protein family (MTH1598/TM1083) 4 142 3.7E-46 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 A3L01_04370 94ce0123fb5fe1dd22fe721fb241308a 142 Gene3D G3DSA:3.55.10.10 1 142 2.2E-52 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 A3L01_04370 94ce0123fb5fe1dd22fe721fb241308a 142 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 8 142 2.0E-32 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 A3L01_01450 a021ee346f8815de8cf7fc9da903a655 356 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 131 1.3E-20 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 A3L01_01450 a021ee346f8815de8cf7fc9da903a655 356 SUPERFAMILY SSF53092 2 129 2.27E-18 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L01_01450 a021ee346f8815de8cf7fc9da903a655 356 Gene3D G3DSA:3.40.350.10 1 129 2.7E-34 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L01_01450 a021ee346f8815de8cf7fc9da903a655 356 Pfam PF00557 Metallopeptidase family M24 138 338 9.3E-68 T 23-10-2018 IPR000994 Peptidase M24 A3L01_01450 a021ee346f8815de8cf7fc9da903a655 356 SUPERFAMILY SSF55920 130 355 2.09E-75 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like A3L01_01450 a021ee346f8815de8cf7fc9da903a655 356 Gene3D G3DSA:3.90.230.10 131 355 3.1E-82 T 23-10-2018 A3L01_01450 a021ee346f8815de8cf7fc9da903a655 356 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 286 298 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site A3L01_01800 77cd5d874a8bda093a043071386406c5 247 TIGRFAM TIGR01486 HAD-SF-IIB-MPGP: mannosyl-3-phosphoglycerate phosphatase family 3 231 2.0E-63 T 23-10-2018 IPR006381 HAD-superfamily hydrolase, superfamily IIB, MPGP GO:0005737|GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 A3L01_01800 77cd5d874a8bda093a043071386406c5 247 SUPERFAMILY SSF56784 1 230 2.11E-34 T 23-10-2018 IPR036412 HAD-like superfamily A3L01_01800 77cd5d874a8bda093a043071386406c5 247 Gene3D G3DSA:3.40.50.1000 4 220 6.0E-63 T 23-10-2018 IPR023214 HAD superfamily A3L01_01800 77cd5d874a8bda093a043071386406c5 247 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 225 1.3E-15 T 23-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A3L01_01800 77cd5d874a8bda093a043071386406c5 247 TIGRFAM TIGR02461 osmo_MPG_phos: mannosyl-3-phosphoglycerate phosphatase 3 226 6.4E-77 T 23-10-2018 IPR033980 Mannosyl-3-phosphoglycerate phosphatase, thermophiles GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 A3L01_01800 77cd5d874a8bda093a043071386406c5 247 Pfam PF08282 haloacid dehalogenase-like hydrolase 180 231 3.9E-5 T 23-10-2018 A3L01_01800 77cd5d874a8bda093a043071386406c5 247 Gene3D G3DSA:3.30.980.20 94 180 6.0E-63 T 23-10-2018 A3L01_00515 facd659ae2948e672361ffaa49f655ba 354 Gene3D G3DSA:2.40.50.140 166 320 1.3E-10 T 23-10-2018 A3L01_00515 facd659ae2948e672361ffaa49f655ba 354 Gene3D G3DSA:2.40.50.140 58 159 5.7E-21 T 23-10-2018 A3L01_00515 facd659ae2948e672361ffaa49f655ba 354 SUPERFAMILY SSF50249 181 345 7.45E-16 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_00515 facd659ae2948e672361ffaa49f655ba 354 SUPERFAMILY SSF50249 53 174 3.98E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_00515 facd659ae2948e672361ffaa49f655ba 354 Pfam PF08646 Replication factor-A C terminal domain 193 278 1.4E-9 T 23-10-2018 IPR013955 Replication factor A, C-terminal A3L01_00515 facd659ae2948e672361ffaa49f655ba 354 Pfam PF01336 OB-fold nucleic acid binding domain 73 151 1.0E-11 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L01_10270 fa02b30ff0a2b0ad8d48e278a01c39f8 185 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 5 178 5.1E-87 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A3L01_10270 fa02b30ff0a2b0ad8d48e278a01c39f8 185 Gene3D G3DSA:2.60.120.10 5 184 1.3E-77 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L01_10270 fa02b30ff0a2b0ad8d48e278a01c39f8 185 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 8 177 5.9E-77 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A3L01_10270 fa02b30ff0a2b0ad8d48e278a01c39f8 185 SUPERFAMILY SSF51182 3 181 2.22E-79 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L01_10270 fa02b30ff0a2b0ad8d48e278a01c39f8 185 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 3 177 2.0E-87 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A3L01_06505 abecff8465630f2d45273e8a90e67be1 235 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 2 226 4.5E-53 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 A3L01_06505 abecff8465630f2d45273e8a90e67be1 235 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 104 196 4.1E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_06505 abecff8465630f2d45273e8a90e67be1 235 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 200 1.1E-25 T 23-10-2018 A3L01_06505 abecff8465630f2d45273e8a90e67be1 235 Gene3D G3DSA:1.10.150.240 15 100 1.1E-57 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A3L01_06505 abecff8465630f2d45273e8a90e67be1 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 9.3E-10 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_06505 abecff8465630f2d45273e8a90e67be1 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 114 127 9.3E-10 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_06505 abecff8465630f2d45273e8a90e67be1 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 161 9.3E-10 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_06505 abecff8465630f2d45273e8a90e67be1 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 163 183 9.3E-10 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_06505 abecff8465630f2d45273e8a90e67be1 235 Gene3D G3DSA:3.40.50.1000 3 222 1.1E-57 T 23-10-2018 IPR023214 HAD superfamily A3L01_06505 abecff8465630f2d45273e8a90e67be1 235 SUPERFAMILY SSF56784 1 230 1.35E-48 T 23-10-2018 IPR036412 HAD-like superfamily A3L01_04100 4132f97ab8d63cce0521f0cf03d19cda 114 SUPERFAMILY SSF51182 12 104 1.01E-24 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L01_04100 4132f97ab8d63cce0521f0cf03d19cda 114 Gene3D G3DSA:2.60.120.10 11 106 1.7E-23 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L01_04100 4132f97ab8d63cce0521f0cf03d19cda 114 Pfam PF07883 Cupin domain 32 100 3.4E-19 T 23-10-2018 IPR013096 Cupin 2, conserved barrel A3L01_00655 99641abd833836b8c349faf65b657bef 170 Pfam PF09622 Putative integral membrane protein (DUF2391) 35 163 1.8E-9 T 23-10-2018 IPR024464 Protein of unknown function DUF2391 A3L01_01180 952de151ff61ea4f83945e8fed5384f3 235 SUPERFAMILY SSF51735 2 226 3.41E-47 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_01180 952de151ff61ea4f83945e8fed5384f3 235 Pfam PF00106 short chain dehydrogenase 2 183 5.7E-37 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_01180 952de151ff61ea4f83945e8fed5384f3 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 1.8E-12 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_01180 952de151ff61ea4f83945e8fed5384f3 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 1.8E-12 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_01180 952de151ff61ea4f83945e8fed5384f3 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.8E-12 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_01180 952de151ff61ea4f83945e8fed5384f3 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 2.2E-5 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_01180 952de151ff61ea4f83945e8fed5384f3 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 2.2E-5 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_01180 952de151ff61ea4f83945e8fed5384f3 235 Gene3D G3DSA:3.40.50.720 1 232 6.0E-51 T 23-10-2018 A3L01_06915 815897d2894fbebe26951b68bfeb5877 63 Gene3D G3DSA:1.10.1220.10 11 46 3.1E-10 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A3L01_06915 815897d2894fbebe26951b68bfeb5877 63 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 45 1.8E-9 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A3L01_06915 815897d2894fbebe26951b68bfeb5877 63 SUPERFAMILY SSF47598 4 46 1.39E-12 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A3L01_06180 0b3ea5bbb2302ee53c6271a57f7d7c9c 342 Pfam PF13692 Glycosyl transferases group 1 179 306 4.9E-24 T 23-10-2018 A3L01_06180 0b3ea5bbb2302ee53c6271a57f7d7c9c 342 Pfam PF13439 Glycosyltransferase Family 4 14 168 8.6E-29 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L01_06180 0b3ea5bbb2302ee53c6271a57f7d7c9c 342 Gene3D G3DSA:3.40.50.2000 1 171 4.9E-38 T 23-10-2018 A3L01_06180 0b3ea5bbb2302ee53c6271a57f7d7c9c 342 Gene3D G3DSA:3.40.50.2000 172 314 4.5E-32 T 23-10-2018 A3L01_06180 0b3ea5bbb2302ee53c6271a57f7d7c9c 342 SUPERFAMILY SSF53756 5 341 1.1E-73 T 23-10-2018 A3L01_07385 99166bcc9603362b04808041a4d8f4fb 361 Gene3D G3DSA:3.20.110.20 2 328 5.8E-24 T 23-10-2018 A3L01_07385 99166bcc9603362b04808041a4d8f4fb 361 Pfam PF03065 Glycosyl hydrolase family 57 56 313 2.6E-37 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A3L01_07385 99166bcc9603362b04808041a4d8f4fb 361 SUPERFAMILY SSF88713 2 307 6.67E-36 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L01_06420 3264b249672883e7bd5f76706f6d83af 187 Gene3D G3DSA:3.40.109.10 1 185 7.0E-49 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L01_06420 3264b249672883e7bd5f76706f6d83af 187 SUPERFAMILY SSF55469 1 187 2.36E-46 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L01_06420 3264b249672883e7bd5f76706f6d83af 187 Pfam PF00881 Nitroreductase family 8 165 4.7E-27 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A3L01_03915 54f49bd9ca079e9d919fe9a0a9f3c7a8 171 SUPERFAMILY SSF89028 1 163 1.96E-50 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L01_03915 54f49bd9ca079e9d919fe9a0a9f3c7a8 171 Gene3D G3DSA:1.20.1200.10 24 171 2.2E-49 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L01_03915 54f49bd9ca079e9d919fe9a0a9f3c7a8 171 Pfam PF01923 Cobalamin adenosyltransferase 3 159 2.4E-50 T 23-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L01_03915 54f49bd9ca079e9d919fe9a0a9f3c7a8 171 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 166 5.6E-58 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L01_03915 54f49bd9ca079e9d919fe9a0a9f3c7a8 171 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 20 164 6.0E-56 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L01_07595 d565b15a04768fe333c251481d3bfee1 264 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 213 9.2E-22 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A3L01_07595 d565b15a04768fe333c251481d3bfee1 264 Hamap MF_01084 Diphthine synthase [dphB]. 2 256 36.08 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 A3L01_07595 d565b15a04768fe333c251481d3bfee1 264 Gene3D G3DSA:3.30.950.10 115 264 4.0E-54 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 A3L01_07595 d565b15a04768fe333c251481d3bfee1 264 SUPERFAMILY SSF53790 1 259 1.09E-62 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A3L01_07595 d565b15a04768fe333c251481d3bfee1 264 PIRSF PIRSF036432 2 260 1.1E-98 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 A3L01_07595 d565b15a04768fe333c251481d3bfee1 264 TIGRFAM TIGR00522 dph5: diphthine synthase 3 256 2.8E-101 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 A3L01_07595 d565b15a04768fe333c251481d3bfee1 264 Gene3D G3DSA:3.40.1010.10 1 114 2.8E-40 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A3L01_02360 e0b343e4cc2fda169c273d5aa424655b 109 Pfam PF06677 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 18 50 5.0E-14 T 23-10-2018 IPR009563 Sjoegren syndrome/scleroderma autoantigen 1 A3L01_07375 ef9df72839ee0e55ea168a8410ed7752 386 Pfam PF01266 FAD dependent oxidoreductase 11 355 1.4E-74 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A3L01_07375 ef9df72839ee0e55ea168a8410ed7752 386 SUPERFAMILY SSF51905 10 376 5.24E-62 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_07375 ef9df72839ee0e55ea168a8410ed7752 386 Gene3D G3DSA:3.50.50.60 12 359 2.3E-143 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_07375 ef9df72839ee0e55ea168a8410ed7752 386 Gene3D G3DSA:3.30.9.10 88 315 2.3E-143 T 23-10-2018 A3L01_07375 ef9df72839ee0e55ea168a8410ed7752 386 SUPERFAMILY SSF54373 224 316 9.81E-10 T 23-10-2018 A3L01_04275 44bf86810ef1474f1f4fe80ff1560906 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.7E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_04275 44bf86810ef1474f1f4fe80ff1560906 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 2.7E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_04275 44bf86810ef1474f1f4fe80ff1560906 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 2.7E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_04275 44bf86810ef1474f1f4fe80ff1560906 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.7E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_04275 44bf86810ef1474f1f4fe80ff1560906 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 2.7E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_04275 44bf86810ef1474f1f4fe80ff1560906 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.7E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L01_04275 44bf86810ef1474f1f4fe80ff1560906 268 SUPERFAMILY SSF51735 12 263 2.15E-49 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_04275 44bf86810ef1474f1f4fe80ff1560906 268 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 262 3.4E-30 T 23-10-2018 A3L01_04275 44bf86810ef1474f1f4fe80ff1560906 268 Gene3D G3DSA:3.40.50.720 4 265 6.7E-47 T 23-10-2018 A3L01_06975 6d243b9495790f481fc7c26ddda36784 252 Pfam PF00005 ABC transporter 19 162 5.2E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_06975 6d243b9495790f481fc7c26ddda36784 252 SUPERFAMILY SSF52540 3 226 1.23E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06975 6d243b9495790f481fc7c26ddda36784 252 SMART SM00382 28 220 3.3E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_06975 6d243b9495790f481fc7c26ddda36784 252 Gene3D G3DSA:3.40.50.300 1 244 1.0E-66 T 23-10-2018 A3L01_04295 be7e19e307c704836f2b28c1745ca4e1 380 SUPERFAMILY SSF51338 341 376 4.86E-5 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L01_04295 be7e19e307c704836f2b28c1745ca4e1 380 SUPERFAMILY SSF51556 49 342 5.83E-29 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L01_04295 be7e19e307c704836f2b28c1745ca4e1 380 Gene3D G3DSA:2.30.40.10 37 372 5.5E-73 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L01_04295 be7e19e307c704836f2b28c1745ca4e1 380 Pfam PF01979 Amidohydrolase family 238 369 8.1E-11 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A3L01_04295 be7e19e307c704836f2b28c1745ca4e1 380 Gene3D G3DSA:3.20.20.140 50 338 5.5E-73 T 23-10-2018 A3L01_00940 d5b74a66261f82b018e500b0a622d8cf 154 SUPERFAMILY SSF52833 7 151 4.14E-53 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L01_00940 d5b74a66261f82b018e500b0a622d8cf 154 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 9 147 1.2E-43 T 23-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_00940 d5b74a66261f82b018e500b0a622d8cf 154 PIRSF PIRSF000216 3 154 1.0E-59 T 23-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_00940 d5b74a66261f82b018e500b0a622d8cf 154 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 105 123 - T 23-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_00940 d5b74a66261f82b018e500b0a622d8cf 154 Gene3D G3DSA:1.10.10.1590 2 65 1.7E-20 T 23-10-2018 A3L01_00940 d5b74a66261f82b018e500b0a622d8cf 154 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 8 147 8.8E-54 T 23-10-2018 A3L01_00940 d5b74a66261f82b018e500b0a622d8cf 154 Gene3D G3DSA:3.40.30.10 66 153 7.7E-32 T 23-10-2018 A3L01_01330 94403bba02ba1e5f8aff4313d64e8f19 284 Pfam PF01937 Protein of unknown function DUF89 4 276 3.5E-50 T 23-10-2018 IPR002791 Domain of unknown function DUF89 A3L01_01330 94403bba02ba1e5f8aff4313d64e8f19 284 PIRSF PIRSF006593 1 284 4.2E-93 T 23-10-2018 IPR014444 Uncharacterised conserved protein UCP006593 A3L01_01330 94403bba02ba1e5f8aff4313d64e8f19 284 SUPERFAMILY SSF111321 1 282 9.68E-80 T 23-10-2018 IPR036075 AF1104-like superfamily A3L01_01330 94403bba02ba1e5f8aff4313d64e8f19 284 Gene3D G3DSA:1.10.8.380 1 68 2.3E-28 T 23-10-2018 A3L01_01330 94403bba02ba1e5f8aff4313d64e8f19 284 Gene3D G3DSA:1.10.285.20 69 128 8.6E-15 T 23-10-2018 A3L01_01330 94403bba02ba1e5f8aff4313d64e8f19 284 Gene3D G3DSA:3.40.50.10880 132 284 5.3E-60 T 23-10-2018 A3L01_01300 c3d147b907d22e3964f0985102c90a31 149 SUPERFAMILY SSF54909 61 144 6.57E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L01_01300 c3d147b907d22e3964f0985102c90a31 149 SUPERFAMILY SSF46785 1 61 1.89E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_01300 c3d147b907d22e3964f0985102c90a31 149 Pfam PF01037 Lrp/AsnC ligand binding domain 67 136 5.7E-14 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L01_01300 c3d147b907d22e3964f0985102c90a31 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 9.9E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_01300 c3d147b907d22e3964f0985102c90a31 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 9.9E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_01300 c3d147b907d22e3964f0985102c90a31 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 9.9E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L01_01300 c3d147b907d22e3964f0985102c90a31 149 SMART SM00344 1 107 1.3E-42 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L01_01300 c3d147b907d22e3964f0985102c90a31 149 Gene3D G3DSA:3.30.70.920 53 146 3.2E-21 T 23-10-2018 A3L01_01300 c3d147b907d22e3964f0985102c90a31 149 Gene3D G3DSA:1.10.10.10 1 51 2.1E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_01300 c3d147b907d22e3964f0985102c90a31 149 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 48 4.7E-18 T 23-10-2018 A3L01_01645 c26cae55a617eefa4d59ec3d26777238 481 SUPERFAMILY SSF81324 394 480 6.67E-16 T 23-10-2018 A3L01_01645 c26cae55a617eefa4d59ec3d26777238 481 Gene3D G3DSA:1.10.287.70 387 481 5.1E-13 T 23-10-2018 A3L01_01645 c26cae55a617eefa4d59ec3d26777238 481 Pfam PF07885 Ion channel 403 480 1.1E-12 T 23-10-2018 IPR013099 Potassium channel domain A3L01_07190 7a62d2dee34a68890ee3d40b18a1f4da 368 Gene3D G3DSA:3.40.50.300 1 212 5.5E-40 T 23-10-2018 A3L01_07190 7a62d2dee34a68890ee3d40b18a1f4da 368 SUPERFAMILY SSF46785 291 360 9.25E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_07190 7a62d2dee34a68890ee3d40b18a1f4da 368 Gene3D G3DSA:1.10.8.60 214 291 1.9E-25 T 23-10-2018 A3L01_07190 7a62d2dee34a68890ee3d40b18a1f4da 368 Gene3D G3DSA:1.10.10.10 293 362 1.8E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_07190 7a62d2dee34a68890ee3d40b18a1f4da 368 SUPERFAMILY SSF52540 3 291 5.32E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_07190 7a62d2dee34a68890ee3d40b18a1f4da 368 Pfam PF01637 ATPase domain predominantly from Archaea 15 253 1.1E-13 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L01_07045 b8c8002da3d5bf344e3df6312e7ac07e 212 Gene3D G3DSA:3.40.50.11570 5 208 6.7E-16 T 23-10-2018 A3L01_07045 b8c8002da3d5bf344e3df6312e7ac07e 212 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 14 197 2.0E-14 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L01_08180 da123105823c08c17d818597b1120a09 185 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 10 177 1.6E-42 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L01_08180 da123105823c08c17d818597b1120a09 185 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 1 180 2.4E-78 T 23-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 A3L01_08180 da123105823c08c17d818597b1120a09 185 SUPERFAMILY SSF53323 1 179 1.11E-55 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L01_08180 da123105823c08c17d818597b1120a09 185 Gene3D G3DSA:3.40.920.10 1 182 8.9E-71 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L01_06985 de1bda3e1e6c01115091ddaf542ffbbd 139 Pfam PF01877 RNA binding 8 117 1.6E-17 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 A3L01_06985 de1bda3e1e6c01115091ddaf542ffbbd 139 SUPERFAMILY SSF55282 8 138 2.59E-38 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06985 de1bda3e1e6c01115091ddaf542ffbbd 139 Gene3D G3DSA:3.30.1440.10 3 138 2.3E-43 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06985 de1bda3e1e6c01115091ddaf542ffbbd 139 Hamap MF_01112 UPF0201 protein . 7 136 24.481 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 A3L01_09915 1ca140b94dcceadb4f8c7a1c2d2da758 351 Gene3D G3DSA:1.10.3720.10 115 341 8.4E-17 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_09915 1ca140b94dcceadb4f8c7a1c2d2da758 351 SUPERFAMILY SSF161098 119 327 1.16E-14 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_09915 1ca140b94dcceadb4f8c7a1c2d2da758 351 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 141 344 2.2E-35 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_05820 1ded65de128136c14fa3b897eb5854aa 344 SUPERFAMILY SSF50969 152 329 1.75E-8 T 23-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like A3L01_05820 1ded65de128136c14fa3b897eb5854aa 344 Gene3D G3DSA:2.130.10.10 91 333 3.4E-5 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A3L01_01875 f118624de4f625c9830034ac0bb58dbf 193 Pfam PF03956 Lysine exporter LysO 9 190 1.4E-57 T 23-10-2018 IPR005642 Lysine exporter LysO A3L01_01875 f118624de4f625c9830034ac0bb58dbf 193 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 84 193 4.0E-43 T 23-10-2018 IPR005642 Lysine exporter LysO A3L01_08560 cd6b2b7fa789f725a5bfd9151f320d3c 158 SUPERFAMILY SSF51306 36 89 5.41E-10 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A3L01_08560 cd6b2b7fa789f725a5bfd9151f320d3c 158 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 39 54 7.2E-8 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L01_08560 cd6b2b7fa789f725a5bfd9151f320d3c 158 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 104 115 7.2E-8 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L01_08560 cd6b2b7fa789f725a5bfd9151f320d3c 158 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 5 150 8.1E-33 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L01_08560 cd6b2b7fa789f725a5bfd9151f320d3c 158 Pfam PF00717 Peptidase S24-like 39 89 4.0E-6 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A3L01_05730 6649690eb4873c031198bba7f0c5a83e 411 SUPERFAMILY SSF53748 2 400 6.95E-114 T 23-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_05730 6649690eb4873c031198bba7f0c5a83e 411 Gene3D G3DSA:3.40.50.1260 10 397 6.8E-136 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_05730 6649690eb4873c031198bba7f0c5a83e 411 Pfam PF00162 Phosphoglycerate kinase 5 389 2.4E-104 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_05730 6649690eb4873c031198bba7f0c5a83e 411 PIRSF PIRSF000724 1 407 7.7E-129 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_05730 6649690eb4873c031198bba7f0c5a83e 411 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 13 23 - T 23-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_05730 6649690eb4873c031198bba7f0c5a83e 411 Gene3D G3DSA:3.40.50.1260 189 390 6.8E-136 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_05730 6649690eb4873c031198bba7f0c5a83e 411 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 4 400 34.182 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_05730 6649690eb4873c031198bba7f0c5a83e 411 PRINTS PR00477 Phosphoglycerate kinase family signature 29 51 2.8E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_05730 6649690eb4873c031198bba7f0c5a83e 411 PRINTS PR00477 Phosphoglycerate kinase family signature 105 120 2.8E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_05730 6649690eb4873c031198bba7f0c5a83e 411 PRINTS PR00477 Phosphoglycerate kinase family signature 170 192 2.8E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_05730 6649690eb4873c031198bba7f0c5a83e 411 PRINTS PR00477 Phosphoglycerate kinase family signature 321 346 2.8E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_05730 6649690eb4873c031198bba7f0c5a83e 411 PRINTS PR00477 Phosphoglycerate kinase family signature 354 365 2.8E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_05730 6649690eb4873c031198bba7f0c5a83e 411 PRINTS PR00477 Phosphoglycerate kinase family signature 8 24 2.8E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_05730 6649690eb4873c031198bba7f0c5a83e 411 PRINTS PR00477 Phosphoglycerate kinase family signature 140 162 2.8E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_05730 6649690eb4873c031198bba7f0c5a83e 411 PRINTS PR00477 Phosphoglycerate kinase family signature 376 393 2.8E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_05730 6649690eb4873c031198bba7f0c5a83e 411 PRINTS PR00477 Phosphoglycerate kinase family signature 193 212 2.8E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L01_08465 a563ca830148a720a1a3a913b200f3bc 591 Gene3D G3DSA:3.20.20.70 128 401 1.4E-32 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_08465 a563ca830148a720a1a3a913b200f3bc 591 Pfam PF04055 Radical SAM superfamily 142 301 8.4E-20 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L01_08465 a563ca830148a720a1a3a913b200f3bc 591 SUPERFAMILY SSF102114 127 395 5.76E-43 T 23-10-2018 A3L01_08465 a563ca830148a720a1a3a913b200f3bc 591 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 144 155 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L01_08465 a563ca830148a720a1a3a913b200f3bc 591 Pfam PF13353 4Fe-4S single cluster domain 142 225 8.3E-7 T 23-10-2018 A3L01_00625 40336e14ad4874a39a9d6c3e78ea78c0 691 Pfam PF09376 NurA domain 77 524 5.0E-5 T 23-10-2018 IPR018977 NurA domain A3L01_02415 50c2dd24bb52cc4b1f6393d5864b654e 118 Hamap MF_00628 Peptidyl-tRNA hydrolase [pth]. 4 118 29.757 T 23-10-2018 IPR034759 Peptidyl-tRNA hydrolase, archaea GO:0004045 MetaCyc: PWY-6308 A3L01_02415 50c2dd24bb52cc4b1f6393d5864b654e 118 Gene3D G3DSA:3.40.1490.10 1 118 1.1E-47 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 A3L01_02415 50c2dd24bb52cc4b1f6393d5864b654e 118 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 4 117 1.8E-44 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 A3L01_02415 50c2dd24bb52cc4b1f6393d5864b654e 118 SUPERFAMILY SSF102462 3 117 5.41E-43 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 A3L01_02415 50c2dd24bb52cc4b1f6393d5864b654e 118 TIGRFAM TIGR00283 arch_pth2: peptidyl-tRNA hydrolase 5 117 8.2E-43 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 A3L01_02560 36f196d8a727025635478a58ebcc8d94 133 ProDom PD015874 RESOLVASE HOLLIDAY JUNCTION ARCHAEAL HOLLIDAY-JUNCTION TYPE MJ0497 ORF-C21_024 PF1503 NEQ424 10 96 3.0E-28 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal A3L01_02560 36f196d8a727025635478a58ebcc8d94 133 Gene3D G3DSA:3.40.1350.10 1 128 1.8E-38 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A3L01_02560 36f196d8a727025635478a58ebcc8d94 133 PIRSF PIRSF004985 1 126 1.2E-38 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal A3L01_02560 36f196d8a727025635478a58ebcc8d94 133 SUPERFAMILY SSF52980 3 106 4.42E-28 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L01_02560 36f196d8a727025635478a58ebcc8d94 133 Pfam PF01870 Archaeal holliday junction resolvase (hjc) 9 94 1.3E-29 T 23-10-2018 IPR002732 Holliday junction resolvase Hjc A3L01_02560 36f196d8a727025635478a58ebcc8d94 133 Hamap MF_01490 Holliday junction resolvase Hjc [hjc]. 2 125 37.016 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal A3L01_06660 9e307771fa1ce08cd96528fe7e804bba 266 Gene3D G3DSA:3.20.20.70 19 253 4.2E-6 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_06660 9e307771fa1ce08cd96528fe7e804bba 266 Pfam PF04055 Radical SAM superfamily 29 183 7.5E-12 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L01_06660 9e307771fa1ce08cd96528fe7e804bba 266 SUPERFAMILY SSF102114 31 219 8.24E-9 T 23-10-2018 A3L01_01250 529a643455b9785bb794c3c4967b78b6 57 Gene3D G3DSA:3.90.940.50 1 57 6.8E-28 T 23-10-2018 A3L01_01250 529a643455b9785bb794c3c4967b78b6 57 ProSitePatterns PS01111 RNA polymerases K / 14 to 18 Kd subunits signature. 5 19 - T 23-10-2018 IPR020708 DNA-directed RNA polymerase, 14-18kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L01_01250 529a643455b9785bb794c3c4967b78b6 57 PIRSF PIRSF000778 1 57 4.3E-22 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L01_01250 529a643455b9785bb794c3c4967b78b6 57 Hamap MF_00192 DNA-directed RNA polymerase subunit K [rpoK]. 2 57 21.785 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L01_01250 529a643455b9785bb794c3c4967b78b6 57 Pfam PF01192 RNA polymerase Rpb6 5 51 4.9E-11 T 23-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L01_01250 529a643455b9785bb794c3c4967b78b6 57 SUPERFAMILY SSF63562 3 55 4.58E-20 T 23-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L01_03780 2b71d09130176a503723a975bb8eb4af 349 Gene3D G3DSA:3.90.550.10 32 245 2.4E-49 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_03780 2b71d09130176a503723a975bb8eb4af 349 SUPERFAMILY SSF53448 36 256 9.85E-57 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_03780 2b71d09130176a503723a975bb8eb4af 349 Pfam PF00535 Glycosyl transferase family 2 40 200 7.6E-38 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L01_00490 2af60b980708f397c607c67cc4daea9e 355 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 34 209 6.8E-40 T 23-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain A3L01_00490 2af60b980708f397c607c67cc4daea9e 355 SUPERFAMILY SSF52540 8 137 5.12E-15 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_00490 2af60b980708f397c607c67cc4daea9e 355 SMART SM00382 26 345 0.0015 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_00490 2af60b980708f397c607c67cc4daea9e 355 Gene3D G3DSA:3.40.50.300 19 214 3.1E-27 T 23-10-2018 A3L01_00705 47ff1d7d6d9b020e025598cff2d5ec84 96 Gene3D G3DSA:1.10.10.10 1 94 1.2E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_00705 47ff1d7d6d9b020e025598cff2d5ec84 96 Pfam PF03551 Transcriptional regulator PadR-like family 11 80 3.7E-20 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L01_00705 47ff1d7d6d9b020e025598cff2d5ec84 96 SUPERFAMILY SSF46785 2 92 1.27E-26 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_00920 58278d4ce207647e07d5059e2c44f345 415 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 402 411 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 A3L01_00920 58278d4ce207647e07d5059e2c44f345 415 SUPERFAMILY SSF56762 2 411 4.71E-92 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_00920 58278d4ce207647e07d5059e2c44f345 415 Pfam PF00374 Nickel-dependent hydrogenase 221 411 1.6E-17 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L01_00920 58278d4ce207647e07d5059e2c44f345 415 Pfam PF00374 Nickel-dependent hydrogenase 39 122 2.6E-14 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L01_00920 58278d4ce207647e07d5059e2c44f345 415 Gene3D G3DSA:1.10.645.10 1 411 3.8E-99 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_07970 a15bf0c9d2b78a2cc7251f25ba44591b 449 Gene3D G3DSA:3.40.120.10 247 330 3.1E-53 T 23-10-2018 A3L01_07970 a15bf0c9d2b78a2cc7251f25ba44591b 449 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 132 5.6E-45 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_07970 a15bf0c9d2b78a2cc7251f25ba44591b 449 SUPERFAMILY SSF53738 150 249 1.77E-23 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_07970 a15bf0c9d2b78a2cc7251f25ba44591b 449 SUPERFAMILY SSF53738 252 355 3.57E-22 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_07970 a15bf0c9d2b78a2cc7251f25ba44591b 449 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 90 99 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_07970 a15bf0c9d2b78a2cc7251f25ba44591b 449 Hamap MF_01554_A Phosphoglucosamine mutase [glmM]. 2 446 51.606 T 23-10-2018 IPR023666 Phosphoglucosamine mutase, archaeal GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_07970 a15bf0c9d2b78a2cc7251f25ba44591b 449 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 254 357 2.7E-18 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_07970 a15bf0c9d2b78a2cc7251f25ba44591b 449 SUPERFAMILY SSF55957 348 447 2.49E-23 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_07970 a15bf0c9d2b78a2cc7251f25ba44591b 449 Gene3D G3DSA:3.40.120.10 164 345 3.1E-53 T 23-10-2018 A3L01_07970 a15bf0c9d2b78a2cc7251f25ba44591b 449 Gene3D G3DSA:3.30.310.50 360 446 2.8E-21 T 23-10-2018 A3L01_07970 a15bf0c9d2b78a2cc7251f25ba44591b 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 89 103 1.3E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_07970 a15bf0c9d2b78a2cc7251f25ba44591b 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 226 241 1.3E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_07970 a15bf0c9d2b78a2cc7251f25ba44591b 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 165 184 1.3E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_07970 a15bf0c9d2b78a2cc7251f25ba44591b 449 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 151 246 9.1E-21 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_07970 a15bf0c9d2b78a2cc7251f25ba44591b 449 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 442 2.6E-163 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_07970 a15bf0c9d2b78a2cc7251f25ba44591b 449 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 366 441 1.2E-7 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_07970 a15bf0c9d2b78a2cc7251f25ba44591b 449 SUPERFAMILY SSF53738 3 171 1.14E-46 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L01_07970 a15bf0c9d2b78a2cc7251f25ba44591b 449 Gene3D G3DSA:3.40.120.10 1 147 2.3E-51 T 23-10-2018 A3L01_03460 b3264c384ddbe601232b55b84e1db79b 190 PIRSF PIRSF037253 2 190 3.2E-79 T 23-10-2018 IPR017158 Transcription regulator, CBS domain-containing, predicted A3L01_03460 b3264c384ddbe601232b55b84e1db79b 190 SMART SM00116 77 124 2.0E-5 T 23-10-2018 IPR000644 CBS domain A3L01_03460 b3264c384ddbe601232b55b84e1db79b 190 SMART SM00116 141 187 0.21 T 23-10-2018 IPR000644 CBS domain A3L01_03460 b3264c384ddbe601232b55b84e1db79b 190 Gene3D G3DSA:3.10.580.10 64 186 1.5E-26 T 23-10-2018 A3L01_03460 b3264c384ddbe601232b55b84e1db79b 190 Pfam PF00571 CBS domain 134 184 6.1E-7 T 23-10-2018 IPR000644 CBS domain A3L01_03460 b3264c384ddbe601232b55b84e1db79b 190 Pfam PF00571 CBS domain 70 121 1.5E-11 T 23-10-2018 IPR000644 CBS domain A3L01_03460 b3264c384ddbe601232b55b84e1db79b 190 Gene3D G3DSA:1.10.260.40 10 63 2.2E-15 T 23-10-2018 A3L01_03460 b3264c384ddbe601232b55b84e1db79b 190 SMART SM00530 12 68 1.6E-12 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L01_03460 b3264c384ddbe601232b55b84e1db79b 190 SUPERFAMILY SSF54631 68 184 5.05E-26 T 23-10-2018 A3L01_03460 b3264c384ddbe601232b55b84e1db79b 190 SUPERFAMILY SSF47413 11 60 2.57E-13 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L01_03460 b3264c384ddbe601232b55b84e1db79b 190 Pfam PF01381 Helix-turn-helix 13 60 6.9E-14 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L01_06300 eb8ddfde5e516f2d1b740c2db19fd8d7 89 Gene3D G3DSA:3.10.440.10 2 89 3.5E-26 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06300 eb8ddfde5e516f2d1b740c2db19fd8d7 89 SUPERFAMILY SSF54575 6 83 6.02E-23 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06300 eb8ddfde5e516f2d1b740c2db19fd8d7 89 Hamap MF_00410 50S ribosomal protein L31e [rpl31e]. 3 89 22.603 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06300 eb8ddfde5e516f2d1b740c2db19fd8d7 89 ProDom PD006030 RIBOSOMAL 60S L31 RIBONUCLEOPROTEIN L31E 50S L31 SUBUNIT STRAIN PHOSPHORYLATION 12 57 2.0E-17 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06300 eb8ddfde5e516f2d1b740c2db19fd8d7 89 SMART SM01380 7 85 2.4E-19 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06300 eb8ddfde5e516f2d1b740c2db19fd8d7 89 ProSitePatterns PS01144 Ribosomal protein L31e signature. 47 61 - T 23-10-2018 IPR020052 Ribosomal protein L31e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06300 eb8ddfde5e516f2d1b740c2db19fd8d7 89 Pfam PF01198 Ribosomal protein L31e 12 79 1.9E-9 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_03655 a249a020688faf2c4ac271fd56b902e4 284 Gene3D G3DSA:3.40.50.970 68 264 6.3E-33 T 23-10-2018 A3L01_03655 a249a020688faf2c4ac271fd56b902e4 284 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 57 205 5.4E-39 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L01_03655 a249a020688faf2c4ac271fd56b902e4 284 SUPERFAMILY SSF52518 19 268 1.35E-74 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L01_07680 eccc943d6504395923cec1d497b97c78 304 Pfam PF01895 PhoU domain 138 230 3.5E-15 T 23-10-2018 IPR026022 PhoU domain A3L01_07680 eccc943d6504395923cec1d497b97c78 304 SMART SM00966 8 54 2.2E-9 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L01_07680 eccc943d6504395923cec1d497b97c78 304 SUPERFAMILY SSF109755 125 301 2.35E-18 T 23-10-2018 A3L01_07680 eccc943d6504395923cec1d497b97c78 304 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 51 8.2E-8 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L01_07680 eccc943d6504395923cec1d497b97c78 304 Gene3D G3DSA:1.20.58.220 134 236 8.7E-13 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L01_09090 a1a6609ef80363b126f1dbc77e503e84 223 Gene3D G3DSA:3.40.1350.10 98 209 7.9E-43 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A3L01_09090 a1a6609ef80363b126f1dbc77e503e84 223 Pfam PF01939 Endonuclease NucS 2 219 1.6E-90 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 A3L01_09090 a1a6609ef80363b126f1dbc77e503e84 223 Hamap MF_00722 Endonuclease NucS [nucS]. 1 214 38.84 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 A3L01_09090 a1a6609ef80363b126f1dbc77e503e84 223 Gene3D G3DSA:2.70.180.20 1 97 7.4E-38 T 23-10-2018 A3L01_07110 4d5d99a80ca0cd8961e3ec6586ae8d9c 96 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 9 93 5.6E-16 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A3L01_06155 b701d475f3af099f9d2f06a166e113ba 602 Gene3D G3DSA:3.40.50.1010 1 127 3.5E-33 T 23-10-2018 A3L01_06155 b701d475f3af099f9d2f06a166e113ba 602 SUPERFAMILY SSF54814 465 520 2.75E-6 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L01_06155 b701d475f3af099f9d2f06a166e113ba 602 SMART SM00670 2 115 3.1E-21 T 23-10-2018 IPR002716 PIN domain A3L01_06155 b701d475f3af099f9d2f06a166e113ba 602 Gene3D G3DSA:3.40.50.300 232 391 1.4E-16 T 23-10-2018 A3L01_06155 b701d475f3af099f9d2f06a166e113ba 602 SUPERFAMILY SSF88723 1 131 1.21E-16 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L01_06155 b701d475f3af099f9d2f06a166e113ba 602 SUPERFAMILY SSF52540 134 440 1.47E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06155 b701d475f3af099f9d2f06a166e113ba 602 Pfam PF00437 Type II/IV secretion system protein 213 370 4.5E-8 T 23-10-2018 IPR001482 Type II/IV secretion system protein A3L01_09440 fbb294c0f617da137f87aef115163752 75 SUPERFAMILY SSF47598 7 49 1.1E-6 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A3L01_07675 77e8282a2263ab682bbf614c2702f57d 306 Gene3D G3DSA:3.60.20.30 176 303 1.1E-33 T 23-10-2018 A3L01_07675 77e8282a2263ab682bbf614c2702f57d 306 Pfam PF01112 Asparaginase 3 297 6.2E-93 T 23-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 A3L01_07675 77e8282a2263ab682bbf614c2702f57d 306 SUPERFAMILY SSF56235 18 299 6.43E-87 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L01_08855 79a4c5bb6338295c339f6dc9efc1dec6 199 Gene3D G3DSA:1.10.1760.20 36 194 6.0E-48 T 23-10-2018 A3L01_08855 79a4c5bb6338295c339f6dc9efc1dec6 199 Pfam PF07155 ECF-type riboflavin transporter, S component 39 190 9.6E-40 T 23-10-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 A3L01_04080 f7ab2315a65bfd68cd3bb5e68b269e91 674 Pfam PF08308 PEGA domain 582 647 8.4E-16 T 23-10-2018 IPR013229 PEGA A3L01_04080 f7ab2315a65bfd68cd3bb5e68b269e91 674 Pfam PF08308 PEGA domain 442 506 2.3E-9 T 23-10-2018 IPR013229 PEGA A3L01_04080 f7ab2315a65bfd68cd3bb5e68b269e91 674 Pfam PF08308 PEGA domain 508 577 5.3E-11 T 23-10-2018 IPR013229 PEGA A3L01_00695 6a02116a8c170078cad43a92e8a55437 329 PRINTS PR00139 Asparaginase/glutaminase family signature 77 95 1.4E-14 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L01_00695 6a02116a8c170078cad43a92e8a55437 329 PRINTS PR00139 Asparaginase/glutaminase family signature 250 268 1.4E-14 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L01_00695 6a02116a8c170078cad43a92e8a55437 329 PRINTS PR00139 Asparaginase/glutaminase family signature 3 14 1.4E-14 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L01_00695 6a02116a8c170078cad43a92e8a55437 329 Pfam PF00710 Asparaginase, N-terminal 2 186 2.1E-57 T 23-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A3L01_00695 6a02116a8c170078cad43a92e8a55437 329 SMART SM00870 2 313 2.7E-115 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L01_00695 6a02116a8c170078cad43a92e8a55437 329 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 5 13 - T 23-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 A3L01_00695 6a02116a8c170078cad43a92e8a55437 329 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 3 324 4.2E-87 T 23-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 A3L01_00695 6a02116a8c170078cad43a92e8a55437 329 Gene3D G3DSA:3.40.50.1170 1 196 2.6E-66 T 23-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 A3L01_00695 6a02116a8c170078cad43a92e8a55437 329 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 78 88 - T 23-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 A3L01_00695 6a02116a8c170078cad43a92e8a55437 329 PIRSF PIRSF001220 1 324 2.5E-90 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L01_00695 6a02116a8c170078cad43a92e8a55437 329 Gene3D G3DSA:3.40.50.40 200 326 7.4E-40 T 23-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 A3L01_00695 6a02116a8c170078cad43a92e8a55437 329 PIRSF PIRSF500176 1 322 2.2E-93 T 23-10-2018 A3L01_00695 6a02116a8c170078cad43a92e8a55437 329 SUPERFAMILY SSF53774 2 325 8.5E-95 T 23-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 A3L01_07405 2f534161350cd67e2f783b549b01fc4e 417 PRINTS PR00131 Glycosyl hydrolase family 1 signature 328 339 4.4E-20 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L01_07405 2f534161350cd67e2f783b549b01fc4e 417 PRINTS PR00131 Glycosyl hydrolase family 1 signature 316 324 4.4E-20 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L01_07405 2f534161350cd67e2f783b549b01fc4e 417 PRINTS PR00131 Glycosyl hydrolase family 1 signature 349 366 4.4E-20 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L01_07405 2f534161350cd67e2f783b549b01fc4e 417 PRINTS PR00131 Glycosyl hydrolase family 1 signature 373 385 4.4E-20 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L01_07405 2f534161350cd67e2f783b549b01fc4e 417 PRINTS PR00131 Glycosyl hydrolase family 1 signature 256 270 4.4E-20 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L01_07405 2f534161350cd67e2f783b549b01fc4e 417 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 316 324 - T 23-10-2018 IPR018120 Glycoside hydrolase family 1, active site A3L01_07405 2f534161350cd67e2f783b549b01fc4e 417 SUPERFAMILY SSF51445 2 408 1.81E-123 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L01_07405 2f534161350cd67e2f783b549b01fc4e 417 Gene3D G3DSA:3.20.20.80 1 417 4.0E-137 T 23-10-2018 A3L01_07405 2f534161350cd67e2f783b549b01fc4e 417 Pfam PF00232 Glycosyl hydrolase family 1 3 401 3.3E-84 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L01_06500 7056f162e7816fd98a37e9579c127c15 188 Pfam PF01066 CDP-alcohol phosphatidyltransferase 26 90 2.4E-15 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A3L01_06500 7056f162e7816fd98a37e9579c127c15 188 Gene3D G3DSA:1.20.120.1760 7 188 1.2E-51 T 23-10-2018 A3L01_06500 7056f162e7816fd98a37e9579c127c15 188 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 90 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A3L01_05150 b842b9e70637bc38b23d75e28623191d 428 Gene3D G3DSA:1.10.3860.10 2 428 6.6E-172 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A3L01_05150 b842b9e70637bc38b23d75e28623191d 428 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 45 60 - T 23-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site A3L01_05150 b842b9e70637bc38b23d75e28623191d 428 PRINTS PR00173 Glutamate-aspartate symporter signature 53 73 1.1E-48 T 23-10-2018 A3L01_05150 b842b9e70637bc38b23d75e28623191d 428 PRINTS PR00173 Glutamate-aspartate symporter signature 82 107 1.1E-48 T 23-10-2018 A3L01_05150 b842b9e70637bc38b23d75e28623191d 428 PRINTS PR00173 Glutamate-aspartate symporter signature 10 30 1.1E-48 T 23-10-2018 A3L01_05150 b842b9e70637bc38b23d75e28623191d 428 PRINTS PR00173 Glutamate-aspartate symporter signature 201 220 1.1E-48 T 23-10-2018 A3L01_05150 b842b9e70637bc38b23d75e28623191d 428 PRINTS PR00173 Glutamate-aspartate symporter signature 232 251 1.1E-48 T 23-10-2018 A3L01_05150 b842b9e70637bc38b23d75e28623191d 428 PRINTS PR00173 Glutamate-aspartate symporter signature 337 356 1.1E-48 T 23-10-2018 A3L01_05150 b842b9e70637bc38b23d75e28623191d 428 PRINTS PR00173 Glutamate-aspartate symporter signature 364 384 1.1E-48 T 23-10-2018 A3L01_05150 b842b9e70637bc38b23d75e28623191d 428 PRINTS PR00173 Glutamate-aspartate symporter signature 302 328 1.1E-48 T 23-10-2018 A3L01_05150 b842b9e70637bc38b23d75e28623191d 428 SUPERFAMILY SSF118215 13 418 4.32E-121 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A3L01_05150 b842b9e70637bc38b23d75e28623191d 428 Pfam PF00375 Sodium:dicarboxylate symporter family 13 416 1.8E-125 T 23-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A3L01_01455 b05bec04c7449a980d2f8235b5aa1dfe 194 ProSitePatterns PS01194 Ribosomal protein L15e signature. 46 69 - T 23-10-2018 IPR020925 Ribosomal protein L15e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01455 b05bec04c7449a980d2f8235b5aa1dfe 194 Gene3D G3DSA:3.40.1120.10 1 193 3.2E-90 T 23-10-2018 IPR024794 Ribosomal protein L15e core domain superfamily GO:0003735|GO:0005840 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01455 b05bec04c7449a980d2f8235b5aa1dfe 194 Pfam PF00827 Ribosomal L15 2 189 1.0E-89 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01455 b05bec04c7449a980d2f8235b5aa1dfe 194 SMART SM01384 2 191 4.0E-135 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01455 b05bec04c7449a980d2f8235b5aa1dfe 194 SUPERFAMILY SSF54189 1 191 1.63E-87 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01455 b05bec04c7449a980d2f8235b5aa1dfe 194 Hamap MF_00256 50S ribosomal protein L15e [rpl15e]. 1 193 43.196 T 23-10-2018 IPR020926 Ribosomal protein L15e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_09255 18abe5df48108d092491005da9a2bf0e 354 Gene3D G3DSA:1.20.81.30 173 285 5.1E-12 T 23-10-2018 A3L01_09255 18abe5df48108d092491005da9a2bf0e 354 Pfam PF00482 Type II secretion system (T2SS), protein F 185 310 6.1E-24 T 23-10-2018 IPR018076 Type II secretion system F domain A3L01_03200 fba428c789ca6357541af0810163aad8 139 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 10 110 6.8E-28 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L01_03200 fba428c789ca6357541af0810163aad8 139 Pfam PF03334 Na+/H+ antiporter subunit 11 95 4.6E-25 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L01_01835 8a37503de78bd84ac022e47a361ea19b 204 Gene3D G3DSA:1.10.1760.20 1 197 3.3E-64 T 23-10-2018 A3L01_01835 8a37503de78bd84ac022e47a361ea19b 204 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 195 1.0E-60 T 23-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 A3L01_01925 dabcedbde47faf3f6f84672a6ee36df3 427 Gene3D G3DSA:3.50.50.60 343 427 5.7E-11 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_01925 dabcedbde47faf3f6f84672a6ee36df3 427 Pfam PF05199 GMC oxidoreductase 369 419 5.4E-11 T 23-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 A3L01_01925 dabcedbde47faf3f6f84672a6ee36df3 427 SUPERFAMILY SSF51905 1 426 3.18E-41 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_01925 dabcedbde47faf3f6f84672a6ee36df3 427 Gene3D G3DSA:3.50.50.60 1 123 5.7E-11 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_01925 dabcedbde47faf3f6f84672a6ee36df3 427 Gene3D G3DSA:3.50.50.60 163 275 3.6E-9 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_01925 dabcedbde47faf3f6f84672a6ee36df3 427 Pfam PF00732 GMC oxidoreductase 6 240 7.5E-22 T 23-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A3L01_06995 78b2dd95abf1115ed256d10a491391f5 185 Hamap MF_01111 UPF0200 protein . 2 182 32.052 T 23-10-2018 IPR022970 Nucleoside triphosphate hydrolase-related A3L01_06995 78b2dd95abf1115ed256d10a491391f5 185 Gene3D G3DSA:3.40.50.300 1 183 2.1E-44 T 23-10-2018 A3L01_06995 78b2dd95abf1115ed256d10a491391f5 185 SUPERFAMILY SSF52540 1 182 2.13E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06995 78b2dd95abf1115ed256d10a491391f5 185 Pfam PF13207 AAA domain 6 137 9.0E-20 T 23-10-2018 A3L01_10210 20883dc40ea7fcc7740a413334cfb2b8 432 Pfam PF01882 Protein of unknown function DUF58 182 260 3.5E-20 T 23-10-2018 IPR002881 Domain of unknown function DUF58 A3L01_10070 f9ea47b4e0acc97dba39a37055dcbda0 422 SUPERFAMILY SSF161098 176 421 1.2E-52 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_10070 f9ea47b4e0acc97dba39a37055dcbda0 422 SUPERFAMILY SSF161098 9 68 2.88E-6 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_10070 f9ea47b4e0acc97dba39a37055dcbda0 422 Gene3D G3DSA:1.10.3720.10 3 83 1.7E-7 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_10070 f9ea47b4e0acc97dba39a37055dcbda0 422 Gene3D G3DSA:1.10.3720.10 176 412 1.3E-45 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_10070 f9ea47b4e0acc97dba39a37055dcbda0 422 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 229 408 1.1E-13 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_02085 7af83b41aa76c336342cccffa9c72dac 296 Gene3D G3DSA:3.40.50.300 1 227 4.2E-66 T 23-10-2018 A3L01_02085 7af83b41aa76c336342cccffa9c72dac 296 Pfam PF00005 ABC transporter 19 154 4.6E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_02085 7af83b41aa76c336342cccffa9c72dac 296 SMART SM00382 28 248 8.3E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_02085 7af83b41aa76c336342cccffa9c72dac 296 SUPERFAMILY SSF52540 3 214 6.22E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_02085 7af83b41aa76c336342cccffa9c72dac 296 Pfam PF13732 Domain of unknown function (DUF4162) 207 291 2.1E-10 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 A3L01_06025 4c3cd82018082a97741d78c4a68f7d78 259 PIRSF PIRSF003092 1 259 3.9E-65 T 23-10-2018 IPR025501 ATP binding protein MinD A3L01_06025 4c3cd82018082a97741d78c4a68f7d78 259 SUPERFAMILY SSF52540 3 236 3.34E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06025 4c3cd82018082a97741d78c4a68f7d78 259 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 4 251 3.2E-117 T 23-10-2018 IPR010224 ATP binding protein MinD, archaea A3L01_06025 4c3cd82018082a97741d78c4a68f7d78 259 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 212 3.4E-24 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L01_06025 4c3cd82018082a97741d78c4a68f7d78 259 Gene3D G3DSA:3.40.50.300 4 233 7.6E-67 T 23-10-2018 A3L01_06025 4c3cd82018082a97741d78c4a68f7d78 259 SMART SM00382 3 163 0.0061 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_03410 94e17c706bce8601af7783d24b849c2a 153 PRINTS PR00446 Hydrogen uptake protein signature 15 26 2.3E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L01_03410 94e17c706bce8601af7783d24b849c2a 153 PRINTS PR00446 Hydrogen uptake protein signature 63 79 2.3E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L01_03410 94e17c706bce8601af7783d24b849c2a 153 PRINTS PR00446 Hydrogen uptake protein signature 51 61 2.3E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L01_03410 94e17c706bce8601af7783d24b849c2a 153 PRINTS PR00446 Hydrogen uptake protein signature 3 15 2.3E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L01_03410 94e17c706bce8601af7783d24b849c2a 153 Gene3D G3DSA:3.40.50.1450 1 148 4.2E-36 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L01_03410 94e17c706bce8601af7783d24b849c2a 153 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 4 145 6.1E-32 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L01_03410 94e17c706bce8601af7783d24b849c2a 153 Pfam PF01750 Hydrogenase maturation protease 28 144 6.0E-21 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L01_03410 94e17c706bce8601af7783d24b849c2a 153 SUPERFAMILY SSF53163 1 148 1.26E-31 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L01_02455 e52af3a3509e5cf15f97c0cff70ef962 125 Hamap MF_01223 UPF0212 protein . 1 112 32.377 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A3L01_02455 e52af3a3509e5cf15f97c0cff70ef962 125 Pfam PF04475 Protein of unknown function (DUF555) 3 104 2.8E-40 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A3L01_02455 e52af3a3509e5cf15f97c0cff70ef962 125 ProDom PD020367 UPF0212 RRNAC1165 RRNAC0441 AF0282 VNG1264C MJ0068 PYRAB08340 PH1312 MA1372 TK1194 1 102 3.0E-51 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A3L01_02455 e52af3a3509e5cf15f97c0cff70ef962 125 PIRSF PIRSF016934 1 122 7.0E-53 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A3L01_00430 caf1e6339bd754916775f68a9d1ec5f0 213 Pfam PF04254 Protein of unknown function (DUF432) 51 165 8.9E-28 T 23-10-2018 IPR007366 Protein of unknown function DUF432 A3L01_00430 caf1e6339bd754916775f68a9d1ec5f0 213 PIRSF PIRSF019202 1 213 3.4E-51 T 23-10-2018 IPR007366 Protein of unknown function DUF432 A3L01_02565 4f7c59a8a9fe6633607d7dcbe0d07c25 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 89 121 3.1E-9 T 23-10-2018 IPR001451 Hexapeptide repeat A3L01_02565 4f7c59a8a9fe6633607d7dcbe0d07c25 174 Gene3D G3DSA:2.160.10.10 1 172 2.1E-63 T 23-10-2018 A3L01_02565 4f7c59a8a9fe6633607d7dcbe0d07c25 174 SUPERFAMILY SSF51161 4 169 3.33E-51 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A3L01_03375 02e39c3b383225d9ed5070369838c4ef 123 Gene3D G3DSA:3.40.140.10 2 123 4.2E-29 T 23-10-2018 A3L01_03375 02e39c3b383225d9ed5070369838c4ef 123 SUPERFAMILY SSF102712 3 121 3.53E-29 T 23-10-2018 A3L01_03375 02e39c3b383225d9ed5070369838c4ef 123 Pfam PF14464 Prokaryotic homologs of the JAB domain 10 103 5.6E-11 T 23-10-2018 IPR028090 JAB domain, prokaryotic A3L01_04710 8baa73c7f8d3e67253d3bfc8e6df9e26 203 Hamap MF_00587 tRNA (pseudouridine(54)-N(1))-methyltransferase [trmY]. 1 200 36.29 T 23-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 A3L01_04710 8baa73c7f8d3e67253d3bfc8e6df9e26 203 SUPERFAMILY SSF75217 1 198 8.37E-65 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L01_04710 8baa73c7f8d3e67253d3bfc8e6df9e26 203 Pfam PF04013 Putative SAM-dependent RNA methyltransferase 1 197 3.7E-48 T 23-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 A3L01_04710 8baa73c7f8d3e67253d3bfc8e6df9e26 203 Gene3D G3DSA:3.40.1280.10 1 201 2.0E-68 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L01_10205 268bc48fb4d4ef7f2b39a1aba664921c 309 PIRSF PIRSF002849 1 309 3.9E-130 T 23-10-2018 A3L01_10205 268bc48fb4d4ef7f2b39a1aba664921c 309 SUPERFAMILY SSF52540 10 280 1.65E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_10205 268bc48fb4d4ef7f2b39a1aba664921c 309 Gene3D G3DSA:1.10.8.300 197 305 8.5E-34 T 23-10-2018 A3L01_10205 268bc48fb4d4ef7f2b39a1aba664921c 309 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 37 167 2.2E-62 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A3L01_10205 268bc48fb4d4ef7f2b39a1aba664921c 309 SMART SM00382 34 175 9.3E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_10205 268bc48fb4d4ef7f2b39a1aba664921c 309 Gene3D G3DSA:3.40.50.300 18 183 2.7E-48 T 23-10-2018 A3L01_00370 aa1506eb1376ae37b329088a07288c5e 130 SUPERFAMILY SSF88659 9 48 8.72E-7 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A3L01_00370 aa1506eb1376ae37b329088a07288c5e 130 Gene3D G3DSA:1.10.10.10 1 50 1.9E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_06795 5e07b373e6036f7b501f282ba99b6244 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 65 4.1E-21 T 23-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain A3L01_06795 5e07b373e6036f7b501f282ba99b6244 67 SMART SM00803 12 66 0.002 T 23-10-2018 IPR004823 TATA box binding protein associated factor (TAF) GO:0006352 A3L01_06795 5e07b373e6036f7b501f282ba99b6244 67 Gene3D G3DSA:1.10.20.10 1 67 6.0E-23 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L01_06795 5e07b373e6036f7b501f282ba99b6244 67 SUPERFAMILY SSF47113 3 66 6.79E-20 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L01_01405 f3904aaf047afa393f1ad7ec91941acd 644 SUPERFAMILY SSF56228 9 212 1.7E-64 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L01_01405 f3904aaf047afa393f1ad7ec91941acd 644 SMART SM00790 8 209 8.0E-93 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L01_01405 f3904aaf047afa393f1ad7ec91941acd 644 Gene3D G3DSA:1.10.569.10 278 428 3.4E-73 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L01_01405 f3904aaf047afa393f1ad7ec91941acd 644 SUPERFAMILY SSF48310 213 624 9.16E-68 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L01_01405 f3904aaf047afa393f1ad7ec91941acd 644 Gene3D G3DSA:3.60.9.10 7 212 5.5E-74 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L01_01405 f3904aaf047afa393f1ad7ec91941acd 644 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 275 621 8.6E-71 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L01_01405 f3904aaf047afa393f1ad7ec91941acd 644 Gene3D G3DSA:1.10.599.10 429 621 3.4E-73 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A3L01_01405 f3904aaf047afa393f1ad7ec91941acd 644 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 10 208 4.9E-70 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L01_09685 e0623cfe67c7e081b5ea884a4cf03e5a 91 Pfam PF14947 Winged helix-turn-helix 2 79 2.2E-23 T 23-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain A3L01_09685 e0623cfe67c7e081b5ea884a4cf03e5a 91 Gene3D G3DSA:1.10.10.10 1 90 1.2E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_09685 e0623cfe67c7e081b5ea884a4cf03e5a 91 SUPERFAMILY SSF46785 3 85 4.48E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_03890 ed77d0c2229a5d96547f5810a08ef165 137 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 3.7E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_03890 ed77d0c2229a5d96547f5810a08ef165 137 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 90 105 3.7E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_03890 ed77d0c2229a5d96547f5810a08ef165 137 SMART SM00418 56 134 1.6E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_03890 ed77d0c2229a5d96547f5810a08ef165 137 SUPERFAMILY SSF46785 48 123 3.51E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_03890 ed77d0c2229a5d96547f5810a08ef165 137 Pfam PF01022 Bacterial regulatory protein, arsR family 63 109 1.5E-12 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_03890 ed77d0c2229a5d96547f5810a08ef165 137 Gene3D G3DSA:1.10.10.10 35 125 8.7E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_09460 ae7ba2a701de7130aad619b9ea252298 490 Pfam PF00232 Glycosyl hydrolase family 1 125 480 3.4E-55 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L01_09460 ae7ba2a701de7130aad619b9ea252298 490 Pfam PF00232 Glycosyl hydrolase family 1 3 90 7.8E-9 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L01_09460 ae7ba2a701de7130aad619b9ea252298 490 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 395 403 - T 23-10-2018 IPR018120 Glycoside hydrolase family 1, active site A3L01_09460 ae7ba2a701de7130aad619b9ea252298 490 SUPERFAMILY SSF51445 3 481 1.49E-126 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L01_09460 ae7ba2a701de7130aad619b9ea252298 490 PRINTS PR00131 Glycosyl hydrolase family 1 signature 452 464 3.1E-18 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L01_09460 ae7ba2a701de7130aad619b9ea252298 490 PRINTS PR00131 Glycosyl hydrolase family 1 signature 318 332 3.1E-18 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L01_09460 ae7ba2a701de7130aad619b9ea252298 490 PRINTS PR00131 Glycosyl hydrolase family 1 signature 428 445 3.1E-18 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L01_09460 ae7ba2a701de7130aad619b9ea252298 490 PRINTS PR00131 Glycosyl hydrolase family 1 signature 395 403 3.1E-18 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L01_09460 ae7ba2a701de7130aad619b9ea252298 490 PRINTS PR00131 Glycosyl hydrolase family 1 signature 407 418 3.1E-18 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L01_09460 ae7ba2a701de7130aad619b9ea252298 490 Gene3D G3DSA:3.20.20.80 1 488 3.7E-138 T 23-10-2018 A3L01_01430 8f6283833a9df468a0e7ae2fa6492cfb 509 Pfam PF07690 Major Facilitator Superfamily 14 406 4.3E-41 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L01_01430 8f6283833a9df468a0e7ae2fa6492cfb 509 Gene3D G3DSA:1.20.1720.10 8 217 5.0E-36 T 23-10-2018 A3L01_01430 8f6283833a9df468a0e7ae2fa6492cfb 509 Gene3D G3DSA:1.20.1720.10 220 426 3.6E-13 T 23-10-2018 A3L01_01430 8f6283833a9df468a0e7ae2fa6492cfb 509 SUPERFAMILY SSF103473 4 503 8.89E-57 T 23-10-2018 IPR036259 MFS transporter superfamily A3L01_10140 8c5d2ac65eb387c3b2ceeb06ed85946c 459 SUPERFAMILY SSF55003 270 453 5.1E-37 T 23-10-2018 IPR011068 Nucleotidyltransferase, class I-like, C-terminal GO:0003723|GO:0016779|GO:0031123 A3L01_10140 8c5d2ac65eb387c3b2ceeb06ed85946c 459 Pfam PF01909 Nucleotidyltransferase domain 40 145 1.2E-11 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L01_10140 8c5d2ac65eb387c3b2ceeb06ed85946c 459 Pfam PF09249 tRNA nucleotidyltransferase, second domain 159 282 2.6E-39 T 23-10-2018 IPR015329 tRNA nucleotidyltransferase, substrate binding GO:0004810|GO:0016437 A3L01_10140 8c5d2ac65eb387c3b2ceeb06ed85946c 459 Gene3D G3DSA:3.30.460.10 20 156 2.6E-85 T 23-10-2018 A3L01_10140 8c5d2ac65eb387c3b2ceeb06ed85946c 459 Gene3D G3DSA:3.30.70.1550 364 403 2.8E-23 T 23-10-2018 A3L01_10140 8c5d2ac65eb387c3b2ceeb06ed85946c 459 Gene3D G3DSA:1.10.1410.30 13 282 2.6E-85 T 23-10-2018 A3L01_10140 8c5d2ac65eb387c3b2ceeb06ed85946c 459 Hamap MF_01264 CCA-adding enzyme [cca]. 1 459 157.782 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 A3L01_10140 8c5d2ac65eb387c3b2ceeb06ed85946c 459 SUPERFAMILY SSF81631 157 283 2.75E-37 T 23-10-2018 A3L01_10140 8c5d2ac65eb387c3b2ceeb06ed85946c 459 SUPERFAMILY SSF81301 7 154 5.35E-36 T 23-10-2018 A3L01_10140 8c5d2ac65eb387c3b2ceeb06ed85946c 459 PIRSF PIRSF005335 6 458 1.7E-149 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 A3L01_10140 8c5d2ac65eb387c3b2ceeb06ed85946c 459 TIGRFAM TIGR03671 cca_archaeal: CCA-adding enzyme 10 422 1.0E-139 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 A3L01_10140 8c5d2ac65eb387c3b2ceeb06ed85946c 459 Gene3D G3DSA:3.30.70.590 294 431 2.8E-23 T 23-10-2018 A3L01_02760 c80a6a0f5b416e29834f3156d14ac68e 612 TIGRFAM TIGR01564 S_layer_MJ: S-layer protein 4 609 1.1E-65 T 23-10-2018 IPR006454 S-layer protein GO:0005618 A3L01_02760 c80a6a0f5b416e29834f3156d14ac68e 612 Pfam PF05123 S-layer like family, N-terminal region 4 310 6.1E-42 T 23-10-2018 IPR022650 S-layer protein, N-terminal A3L01_02760 c80a6a0f5b416e29834f3156d14ac68e 612 Pfam PF05124 S-layer like family, C-terminal region 404 609 7.1E-30 T 23-10-2018 IPR022651 S-layer protein, C-terminal A3L01_01290 232208c827c82745eb90c2497789f018 251 PIRSF PIRSF000883 2 251 1.7E-27 T 23-10-2018 IPR011152 Phosphoesterase MJ0912 A3L01_01290 232208c827c82745eb90c2497789f018 251 SUPERFAMILY SSF56300 1 250 5.82E-58 T 23-10-2018 A3L01_01290 232208c827c82745eb90c2497789f018 251 Gene3D G3DSA:3.60.21.10 1 251 5.3E-51 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L01_09780 ed5ac61ab93a6d1f91110073d6bb4ab0 167 Pfam PF03657 Uncharacterised protein family (UPF0113) 6 165 6.4E-11 T 23-10-2018 IPR005155 Ribosome biogenesis factor NIP7-like Reactome: R-HSA-6791226 A3L01_09780 ed5ac61ab93a6d1f91110073d6bb4ab0 167 Gene3D G3DSA:3.10.450.220 1 93 1.3E-44 T 23-10-2018 A3L01_09780 ed5ac61ab93a6d1f91110073d6bb4ab0 167 Gene3D G3DSA:2.30.130.10 94 165 3.2E-20 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L01_00815 6ff754824c5ef30fa52be38f6c04c9b7 131 Pfam PF04472 Cell division protein SepF 57 129 7.1E-14 T 23-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 A3L01_00815 6ff754824c5ef30fa52be38f6c04c9b7 131 PIRSF PIRSF019313 1 131 2.8E-30 T 23-10-2018 IPR012426 Uncharacterised protein family SepF-related, archaea A3L01_00815 6ff754824c5ef30fa52be38f6c04c9b7 131 Gene3D G3DSA:3.30.110.150 47 131 2.7E-25 T 23-10-2018 IPR038594 SepF-like superfamily A3L01_07170 6efda1ed04319d01f1908212b40439d7 224 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 2 224 38.808 T 23-10-2018 IPR022877 Protein of unknown funcion UPF0173 A3L01_07170 6efda1ed04319d01f1908212b40439d7 224 Gene3D G3DSA:3.60.15.10 2 224 2.1E-72 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_07170 6efda1ed04319d01f1908212b40439d7 224 SUPERFAMILY SSF56281 1 223 2.88E-39 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_07170 6efda1ed04319d01f1908212b40439d7 224 Pfam PF13483 Beta-lactamase superfamily domain 3 189 7.3E-32 T 23-10-2018 A3L01_07170 6efda1ed04319d01f1908212b40439d7 224 SMART SM00849 8 189 9.5E-19 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_06835 26c6988635693c9e6553a39827d8cf85 253 Pfam PF00005 ABC transporter 18 161 7.6E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_06835 26c6988635693c9e6553a39827d8cf85 253 Gene3D G3DSA:3.40.50.300 1 242 6.1E-68 T 23-10-2018 A3L01_06835 26c6988635693c9e6553a39827d8cf85 253 SMART SM00382 26 209 2.5E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_06835 26c6988635693c9e6553a39827d8cf85 253 SUPERFAMILY SSF52540 2 222 1.49E-62 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_05750 b44629e0e5a9c2c3750ae871d2d5e1ef 254 PIRSF PIRSF006648 1 253 3.8E-71 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L01_05750 b44629e0e5a9c2c3750ae871d2d5e1ef 254 Pfam PF01061 ABC-2 type transporter 3 216 2.5E-44 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A3L01_05750 b44629e0e5a9c2c3750ae871d2d5e1ef 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 138 162 6.6E-16 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L01_05750 b44629e0e5a9c2c3750ae871d2d5e1ef 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 195 214 6.6E-16 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L01_05750 b44629e0e5a9c2c3750ae871d2d5e1ef 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 175 194 6.6E-16 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L01_05750 b44629e0e5a9c2c3750ae871d2d5e1ef 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 101 126 6.6E-16 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L01_05750 b44629e0e5a9c2c3750ae871d2d5e1ef 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 22 43 6.6E-16 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L01_05750 b44629e0e5a9c2c3750ae871d2d5e1ef 254 TIGRFAM TIGR01247 drrB: daunorubicin resistance ABC transporter membrane protein 10 248 4.7E-118 T 23-10-2018 IPR005942 Daunorubicin resistance ABC transporter membrane protein A3L01_04470 f45fca32d9f60b4382254037dc78b3f6 510 SUPERFAMILY SSF56300 1 234 3.94E-49 T 23-10-2018 A3L01_04470 f45fca32d9f60b4382254037dc78b3f6 510 SUPERFAMILY SSF56300 269 481 3.8E-28 T 23-10-2018 A3L01_04470 f45fca32d9f60b4382254037dc78b3f6 510 Pfam PF00149 Calcineurin-like phosphoesterase 1 184 1.7E-19 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L01_04470 f45fca32d9f60b4382254037dc78b3f6 510 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 281 471 1.6E-7 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L01_04470 f45fca32d9f60b4382254037dc78b3f6 510 Gene3D G3DSA:3.60.21.10 257 492 1.2E-18 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L01_04470 f45fca32d9f60b4382254037dc78b3f6 510 Gene3D G3DSA:3.60.21.10 1 252 6.7E-39 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L01_08150 4036353bcbcb094fb3ec90701b6a06cb 75 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 1 39 1.2E-7 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L01_08150 4036353bcbcb094fb3ec90701b6a06cb 75 SUPERFAMILY SSF89447 2 51 3.01E-6 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L01_06005 e2cb44eca5439c073b7ac161281d55c3 282 Gene3D G3DSA:1.10.1670.10 215 272 3.8E-7 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A3L01_06005 e2cb44eca5439c073b7ac161281d55c3 282 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 105 250 2.1E-14 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A3L01_06005 e2cb44eca5439c073b7ac161281d55c3 282 SUPERFAMILY SSF48150 88 266 7.85E-37 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A3L01_06005 e2cb44eca5439c073b7ac161281d55c3 282 SMART SM00478 109 267 3.3E-21 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A3L01_06005 e2cb44eca5439c073b7ac161281d55c3 282 Gene3D G3DSA:1.10.340.30 99 214 9.4E-25 T 23-10-2018 A3L01_05135 f57c4608b7a6c679a6848f3a04379529 221 Gene3D G3DSA:3.40.50.11570 6 217 4.2E-56 T 23-10-2018 A3L01_05135 f57c4608b7a6c679a6848f3a04379529 221 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 11 214 2.8E-51 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L01_08745 41be0f93a72c4fa288df403d41afa158 99 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 32 83 5.0E-18 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A3L01_07545 72011b4f822fd4a58905b4b92f3d788e 67 SUPERFAMILY SSF54862 3 65 1.32E-14 T 23-10-2018 A3L01_07545 72011b4f822fd4a58905b4b92f3d788e 67 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 62 6.6E-17 T 23-10-2018 A3L01_07545 72011b4f822fd4a58905b4b92f3d788e 67 Gene3D G3DSA:3.30.70.20 2 67 3.0E-23 T 23-10-2018 A3L01_07545 72011b4f822fd4a58905b4b92f3d788e 67 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 2.2E-9 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A3L01_07545 72011b4f822fd4a58905b4b92f3d788e 67 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 2.2E-9 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A3L01_07545 72011b4f822fd4a58905b4b92f3d788e 67 PRINTS PR00352 3Fe-4S ferredoxin signature 50 62 2.2E-9 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A3L01_02955 a2c3621bb3c92f4ba6852a183711be08 241 SUPERFAMILY SSF50249 134 223 2.42E-16 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_02955 a2c3621bb3c92f4ba6852a183711be08 241 Gene3D G3DSA:2.40.50.140 125 241 3.7E-35 T 23-10-2018 A3L01_02955 a2c3621bb3c92f4ba6852a183711be08 241 Pfam PF01588 Putative tRNA binding domain 138 224 2.5E-18 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A3L01_02955 a2c3621bb3c92f4ba6852a183711be08 241 Gene3D G3DSA:1.20.1440.150 1 124 1.3E-58 T 23-10-2018 A3L01_09365 9a889f5e35401c4a74565668e5a05667 252 Gene3D G3DSA:3.40.50.300 5 249 1.2E-67 T 23-10-2018 A3L01_08665 735bf8cef1a39399b2c15b210a15ea5a 70 Pfam PF01938 TRAM domain 14 70 5.5E-15 T 23-10-2018 IPR002792 TRAM domain A3L01_08665 735bf8cef1a39399b2c15b210a15ea5a 70 Gene3D G3DSA:2.40.50.140 5 70 4.1E-26 T 23-10-2018 A3L01_08665 735bf8cef1a39399b2c15b210a15ea5a 70 SUPERFAMILY SSF50249 10 70 1.14E-16 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_10100 afbbf66951763092f0a5c120cc7e6afa 120 PIRSF PIRSF004952 4 120 3.7E-46 T 23-10-2018 IPR016434 Ribonuclease P, protein component 2 GO:0001682|GO:0004526 A3L01_10100 afbbf66951763092f0a5c120cc7e6afa 120 Gene3D G3DSA:3.30.70.3250 1 120 1.5E-49 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 A3L01_10100 afbbf66951763092f0a5c120cc7e6afa 120 SUPERFAMILY SSF160350 4 116 2.62E-34 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 A3L01_10100 afbbf66951763092f0a5c120cc7e6afa 120 Pfam PF01900 Rpp14/Pop5 family 17 113 1.1E-22 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 A3L01_10100 afbbf66951763092f0a5c120cc7e6afa 120 Hamap MF_00755 Ribonuclease P protein component 2 [rnp2]. 5 116 26.757 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 A3L01_01685 2a1b7fe6b52ad3d271a967338c296586 74 Gene3D G3DSA:2.40.50.970 1 74 1.2E-33 T 23-10-2018 IPR037254 HupF/HypC superfamily A3L01_01685 2a1b7fe6b52ad3d271a967338c296586 74 Pfam PF01455 HupF/HypC family 1 65 2.6E-30 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L01_01685 2a1b7fe6b52ad3d271a967338c296586 74 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 72 4.0E-28 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L01_01685 2a1b7fe6b52ad3d271a967338c296586 74 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 23-10-2018 IPR019812 Hydrogenase assembly chaperone, conserved site A3L01_01685 2a1b7fe6b52ad3d271a967338c296586 74 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 56 68 4.0E-15 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L01_01685 2a1b7fe6b52ad3d271a967338c296586 74 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 17 33 4.0E-15 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L01_01685 2a1b7fe6b52ad3d271a967338c296586 74 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 38 54 4.0E-15 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L01_01685 2a1b7fe6b52ad3d271a967338c296586 74 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 4.0E-15 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L01_01685 2a1b7fe6b52ad3d271a967338c296586 74 SUPERFAMILY SSF159127 1 73 1.7E-27 T 23-10-2018 IPR037254 HupF/HypC superfamily A3L01_09485 ebc8961987d71d3068389fc72a1dfd13 321 Pfam PF00005 ABC transporter 28 181 1.9E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_09485 ebc8961987d71d3068389fc72a1dfd13 321 SMART SM00382 36 231 3.3E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_09485 ebc8961987d71d3068389fc72a1dfd13 321 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 317 1.2E-21 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L01_09485 ebc8961987d71d3068389fc72a1dfd13 321 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_09485 ebc8961987d71d3068389fc72a1dfd13 321 Gene3D G3DSA:3.40.50.300 1 320 8.5E-90 T 23-10-2018 A3L01_09485 ebc8961987d71d3068389fc72a1dfd13 321 SUPERFAMILY SSF52540 4 263 7.1E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_09485 ebc8961987d71d3068389fc72a1dfd13 321 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 297 2.1E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L01_00190 3658a737ac19e42b666a59cd827db6bb 389 PRINTS PR00423 Cell division protein FtsZ signature 93 113 5.5E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L01_00190 3658a737ac19e42b666a59cd827db6bb 389 PRINTS PR00423 Cell division protein FtsZ signature 183 205 5.5E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L01_00190 3658a737ac19e42b666a59cd827db6bb 389 PRINTS PR00423 Cell division protein FtsZ signature 123 144 5.5E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L01_00190 3658a737ac19e42b666a59cd827db6bb 389 SMART SM00864 2 199 1.1E-33 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L01_00190 3658a737ac19e42b666a59cd827db6bb 389 SUPERFAMILY SSF52490 2 199 2.75E-39 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L01_00190 3658a737ac19e42b666a59cd827db6bb 389 Hamap MF_01946 Tubulin-like protein CetZ [cetZ]. 1 354 26.383 T 23-10-2018 IPR032907 Tubulin-like protein CetZ GO:0008360 A3L01_00190 3658a737ac19e42b666a59cd827db6bb 389 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 5 168 1.5E-26 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L01_00190 3658a737ac19e42b666a59cd827db6bb 389 ProSitePatterns PS00227 Tubulin subunits alpha, beta, and gamma signature. 101 107 - T 23-10-2018 IPR017975 Tubulin, conserved site GO:0005525|GO:0005874|GO:0007017 Reactome: R-HSA-380320 A3L01_00190 3658a737ac19e42b666a59cd827db6bb 389 Gene3D G3DSA:3.40.50.1440 2 363 8.8E-86 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L01_07640 c553e66b745b4595658c080bda64f1d0 249 Pfam PF01881 CRISPR associated protein Cas6 95 238 1.2E-30 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L01_07640 c553e66b745b4595658c080bda64f1d0 249 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 50 237 6.1E-43 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L01_07640 c553e66b745b4595658c080bda64f1d0 249 Gene3D G3DSA:3.30.70.1900 123 242 3.3E-37 T 23-10-2018 A3L01_07640 c553e66b745b4595658c080bda64f1d0 249 Gene3D G3DSA:3.30.70.1890 1 121 2.2E-44 T 23-10-2018 A3L01_07640 c553e66b745b4595658c080bda64f1d0 249 PIRSF PIRSF005054 1 242 1.5E-62 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L01_09450 89d7a9f68f193a8d93fc0a343d39f5aa 149 Pfam PF01850 PIN domain 24 118 4.3E-5 T 23-10-2018 IPR002716 PIN domain A3L01_09450 89d7a9f68f193a8d93fc0a343d39f5aa 149 Gene3D G3DSA:3.40.50.1010 1 149 3.0E-43 T 23-10-2018 A3L01_09450 89d7a9f68f193a8d93fc0a343d39f5aa 149 SUPERFAMILY SSF88723 7 145 2.05E-30 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L01_03950 c3c420cb136857cfee5f4fc95f25834b 101 SUPERFAMILY SSF81301 5 99 6.14E-24 T 23-10-2018 A3L01_03950 c3c420cb136857cfee5f4fc95f25834b 101 Gene3D G3DSA:3.30.460.10 5 99 1.1E-22 T 23-10-2018 A3L01_03950 c3c420cb136857cfee5f4fc95f25834b 101 Pfam PF01909 Nucleotidyltransferase domain 15 83 4.8E-17 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L01_05055 8b5aa2dbbbf8d899b83c9d66091c0f04 232 SUPERFAMILY SSF52540 1 216 4.18E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_05055 8b5aa2dbbbf8d899b83c9d66091c0f04 232 Pfam PF00005 ABC transporter 18 155 1.5E-20 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_05055 8b5aa2dbbbf8d899b83c9d66091c0f04 232 Gene3D G3DSA:3.40.50.300 1 224 9.7E-47 T 23-10-2018 A3L01_05055 8b5aa2dbbbf8d899b83c9d66091c0f04 232 SMART SM00382 25 210 3.5E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_05055 8b5aa2dbbbf8d899b83c9d66091c0f04 232 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_09805 e4a1db7a13b67a3b80b5794b59d0047f 507 SUPERFAMILY SSF82866 311 492 2.88E-24 T 23-10-2018 A3L01_09805 e4a1db7a13b67a3b80b5794b59d0047f 507 Hamap MF_01463_A Protein translocase subunit SecD [secD]. 6 506 18.697 T 23-10-2018 IPR024912 Protein translocase subunit SecD, archaeal A3L01_09805 e4a1db7a13b67a3b80b5794b59d0047f 507 Gene3D G3DSA:1.20.1640.10 313 501 4.1E-13 T 23-10-2018 A3L01_09805 e4a1db7a13b67a3b80b5794b59d0047f 507 Gene3D G3DSA:3.30.70.3400 35 118 2.0E-8 T 23-10-2018 A3L01_09805 e4a1db7a13b67a3b80b5794b59d0047f 507 Pfam PF02355 Protein export membrane protein 331 490 1.2E-17 T 23-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A3L01_10105 9b93f8872828c157a320ca338bb21a2c 361 Pfam PF13394 4Fe-4S single cluster domain 31 121 4.3E-5 T 23-10-2018 A3L01_10105 9b93f8872828c157a320ca338bb21a2c 361 SUPERFAMILY SSF102114 27 206 4.45E-22 T 23-10-2018 A3L01_10105 9b93f8872828c157a320ca338bb21a2c 361 Pfam PF04055 Radical SAM superfamily 33 185 1.1E-12 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L01_10105 9b93f8872828c157a320ca338bb21a2c 361 Gene3D G3DSA:3.20.20.70 24 285 5.7E-16 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_02450 e3fae76ad30680d9741dc0d1ec63b29d 95 Pfam PF04010 Protein of unknown function (DUF357) 12 84 8.1E-30 T 23-10-2018 IPR023140 Domain of unknown function DUF357 A3L01_02450 e3fae76ad30680d9741dc0d1ec63b29d 95 SUPERFAMILY SSF158372 4 85 4.45E-26 T 23-10-2018 IPR036809 AF1782-like superfamily A3L01_02450 e3fae76ad30680d9741dc0d1ec63b29d 95 Gene3D G3DSA:1.20.1270.90 5 84 2.0E-25 T 23-10-2018 A3L01_07175 03147b0683e9cf14c190ef4dc6cf6e14 459 Gene3D G3DSA:3.40.50.261 290 458 2.7E-66 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L01_07175 03147b0683e9cf14c190ef4dc6cf6e14 459 SMART SM00881 6 100 1.8E-34 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L01_07175 03147b0683e9cf14c190ef4dc6cf6e14 459 SUPERFAMILY SSF51735 3 138 2.81E-39 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_07175 03147b0683e9cf14c190ef4dc6cf6e14 459 SUPERFAMILY SSF52210 132 288 1.27E-45 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L01_07175 03147b0683e9cf14c190ef4dc6cf6e14 459 Gene3D G3DSA:3.40.50.720 3 129 2.6E-46 T 23-10-2018 A3L01_07175 03147b0683e9cf14c190ef4dc6cf6e14 459 Gene3D G3DSA:3.40.50.261 130 289 5.4E-62 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L01_07175 03147b0683e9cf14c190ef4dc6cf6e14 459 SUPERFAMILY SSF52210 292 449 2.62E-41 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L01_07175 03147b0683e9cf14c190ef4dc6cf6e14 459 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 150 287 1.5E-56 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L01_07175 03147b0683e9cf14c190ef4dc6cf6e14 459 Pfam PF13380 CoA binding domain 10 135 9.8E-27 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L01_07750 5e88d069a24c4b1cd34932336c2cba1c 234 Pfam PF07758 Protein of unknown function (DUF1614) 56 233 4.5E-55 T 23-10-2018 IPR011672 Protein of unknown function DUF1614 A3L01_04170 fc5a370973f3b171502880ee85138396 294 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 292 80.318 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A3L01_04170 fc5a370973f3b171502880ee85138396 294 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 5 288 9.5E-87 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A3L01_04170 fc5a370973f3b171502880ee85138396 294 Pfam PF03186 CobD/Cbib protein 8 267 4.3E-84 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A3L01_01255 72a58b20c267317c29b91f4bcc362c1e 341 PRINTS PR00148 Enolase signature 92 108 1.7E-5 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_01255 72a58b20c267317c29b91f4bcc362c1e 341 PRINTS PR00148 Enolase signature 316 330 1.7E-5 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_01255 72a58b20c267317c29b91f4bcc362c1e 341 SMART SM01193 4 119 5.9E-34 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_01255 72a58b20c267317c29b91f4bcc362c1e 341 Gene3D G3DSA:3.30.390.10 1 111 3.7E-21 T 23-10-2018 IPR029017 Enolase-like, N-terminal A3L01_01255 72a58b20c267317c29b91f4bcc362c1e 341 Pfam PF03952 Enolase, N-terminal domain 38 119 6.8E-23 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_01255 72a58b20c267317c29b91f4bcc362c1e 341 SMART SM01192 124 340 2.6E-13 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_01255 72a58b20c267317c29b91f4bcc362c1e 341 Gene3D G3DSA:3.20.20.120 205 339 7.2E-14 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A3L01_01255 72a58b20c267317c29b91f4bcc362c1e 341 SUPERFAMILY SSF51604 126 337 6.15E-30 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A3L01_01255 72a58b20c267317c29b91f4bcc362c1e 341 Pfam PF00113 Enolase, C-terminal TIM barrel domain 246 334 8.5E-9 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L01_01255 72a58b20c267317c29b91f4bcc362c1e 341 SUPERFAMILY SSF54826 4 125 4.95E-30 T 23-10-2018 A3L01_09535 866e838f5348e6ae906afc846769a160 889 SUPERFAMILY SSF49344 26 207 3.26E-9 T 23-10-2018 A3L01_09535 866e838f5348e6ae906afc846769a160 889 SUPERFAMILY SSF49344 241 439 7.45E-14 T 23-10-2018 A3L01_09535 866e838f5348e6ae906afc846769a160 889 SUPERFAMILY SSF49344 682 837 7.06E-10 T 23-10-2018 A3L01_09535 866e838f5348e6ae906afc846769a160 889 Gene3D G3DSA:2.60.40.10 436 560 1.0E-27 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_09535 866e838f5348e6ae906afc846769a160 889 Pfam PF07705 CARDB 454 552 2.9E-17 T 23-10-2018 IPR011635 CARDB domain A3L01_01945 6882c78bc5e69c3b84121699a2800bd8 102 Gene3D G3DSA:3.30.1330.30 1 101 5.4E-39 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L01_01945 6882c78bc5e69c3b84121699a2800bd8 102 ProSitePatterns PS00709 Ribosomal protein L30e signature 1. 14 38 - T 23-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01945 6882c78bc5e69c3b84121699a2800bd8 102 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 7 95 8.7E-19 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 A3L01_01945 6882c78bc5e69c3b84121699a2800bd8 102 SUPERFAMILY SSF55315 3 97 2.95E-27 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L01_01945 6882c78bc5e69c3b84121699a2800bd8 102 Hamap MF_00481 50S ribosomal protein L30e [rpl30e]. 2 99 29.652 T 23-10-2018 IPR000231 Ribosomal protein L30e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01945 6882c78bc5e69c3b84121699a2800bd8 102 ProSitePatterns PS00993 Ribosomal protein L30e signature 2. 70 90 - T 23-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_05385 8abbbaf5df4de0d2e6172bf5de166b88 239 SMART SM00849 31 221 8.4E-39 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_05385 8abbbaf5df4de0d2e6172bf5de166b88 239 SUPERFAMILY SSF56281 9 235 3.14E-46 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_05385 8abbbaf5df4de0d2e6172bf5de166b88 239 Pfam PF00753 Metallo-beta-lactamase superfamily 31 221 1.1E-24 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_05385 8abbbaf5df4de0d2e6172bf5de166b88 239 Gene3D G3DSA:3.60.15.10 4 234 5.6E-48 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_01640 23906affd1868d955b89da57673b8e7e 316 Pfam PF04055 Radical SAM superfamily 25 191 1.1E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L01_01640 23906affd1868d955b89da57673b8e7e 316 Gene3D G3DSA:3.20.20.70 19 270 2.3E-19 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_01640 23906affd1868d955b89da57673b8e7e 316 SUPERFAMILY SSF102114 25 230 7.06E-21 T 23-10-2018 A3L01_01640 23906affd1868d955b89da57673b8e7e 316 SMART SM00729 15 226 0.0019 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L01_04975 416ea391050084428cb8deb78bc43101 171 Gene3D G3DSA:2.20.28.10 133 171 4.3E-19 T 23-10-2018 A3L01_04975 416ea391050084428cb8deb78bc43101 171 SUPERFAMILY SSF57802 137 170 1.27E-10 T 23-10-2018 A3L01_04975 416ea391050084428cb8deb78bc43101 171 Pfam PF02915 Rubrerythrin 10 124 1.8E-25 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L01_04975 416ea391050084428cb8deb78bc43101 171 Gene3D G3DSA:1.20.1260.10 2 132 1.8E-47 T 23-10-2018 IPR012347 Ferritin-like A3L01_04975 416ea391050084428cb8deb78bc43101 171 SUPERFAMILY SSF47240 5 132 1.16E-37 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L01_01160 8912deaa301a56c599ea2d5927b8319e 175 Pfam PF01956 Integral membrane protein DUF106 13 173 9.2E-28 T 23-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 A3L01_01160 8912deaa301a56c599ea2d5927b8319e 175 SMART SM01415 10 174 3.9E-19 T 23-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 A3L01_07860 0ca86ec91cbab3d23f3334ac81af43d8 240 Pfam PF00005 ABC transporter 18 155 1.4E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_07860 0ca86ec91cbab3d23f3334ac81af43d8 240 SUPERFAMILY SSF52540 8 214 1.95E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_07860 0ca86ec91cbab3d23f3334ac81af43d8 240 Gene3D G3DSA:3.40.50.300 6 237 1.3E-62 T 23-10-2018 A3L01_07860 0ca86ec91cbab3d23f3334ac81af43d8 240 SMART SM00382 27 201 5.2E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_09355 5f1aa71d3db6a73c469428781899b12a 66 TIGRFAM TIGR04140 chp_AF_0576: TIGR04140 family protein 1 66 6.3E-25 T 23-10-2018 IPR026486 Uncharacterised protein AF_0576 A3L01_01750 7c188dd1191282430f03e00c0eb854a6 260 SMART SM00382 28 211 3.1E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_01750 7c188dd1191282430f03e00c0eb854a6 260 SUPERFAMILY SSF52540 4 219 1.15E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_01750 7c188dd1191282430f03e00c0eb854a6 260 Pfam PF00005 ABC transporter 19 163 1.2E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_01750 7c188dd1191282430f03e00c0eb854a6 260 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_01750 7c188dd1191282430f03e00c0eb854a6 260 Gene3D G3DSA:3.40.50.300 3 241 2.2E-64 T 23-10-2018 A3L01_02205 2fa49f5b576d6bf0746d3ba88b812deb 345 Gene3D G3DSA:3.40.190.10 55 336 2.6E-100 T 23-10-2018 A3L01_02205 2fa49f5b576d6bf0746d3ba88b812deb 345 Gene3D G3DSA:3.40.190.10 136 273 2.6E-100 T 23-10-2018 A3L01_02205 2fa49f5b576d6bf0746d3ba88b812deb 345 Pfam PF16868 NMT1-like family 56 336 1.7E-87 T 23-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family A3L01_02205 2fa49f5b576d6bf0746d3ba88b812deb 345 SUPERFAMILY SSF53850 48 337 1.46E-74 T 23-10-2018 A3L01_02205 2fa49f5b576d6bf0746d3ba88b812deb 345 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 1 336 7.5E-99 T 23-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family A3L01_00465 c024a12cb33b1a864798bea5f28b0416 125 SMART SM01405 4 124 1.6E-52 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_00465 c024a12cb33b1a864798bea5f28b0416 125 Pfam PF01092 Ribosomal protein S6e 4 124 3.9E-37 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_00465 c024a12cb33b1a864798bea5f28b0416 125 Hamap MF_00512 30S ribosomal protein S6e [rps6e]. 2 125 18.831 T 23-10-2018 IPR020924 Ribosomal protein S6e, archaeal GO:0003735|GO:0005840|GO:0006412 A3L01_00465 c024a12cb33b1a864798bea5f28b0416 125 ProSitePatterns PS00578 Ribosomal protein S6e signature. 63 74 - T 23-10-2018 IPR018282 Ribosomal protein S6e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_08985 4a878f7444248d240c159f118ed0c99a 278 SUPERFAMILY SSF111331 2 270 2.49E-73 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A3L01_08985 4a878f7444248d240c159f118ed0c99a 278 Gene3D G3DSA:3.40.50.10330 20 267 2.8E-71 T 23-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A3L01_08985 4a878f7444248d240c159f118ed0c99a 278 Hamap MF_00361 NAD kinase [nadK]. 1 276 30.074 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A3L01_08985 4a878f7444248d240c159f118ed0c99a 278 Pfam PF01513 ATP-NAD kinase 2 261 7.6E-70 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A3L01_08985 4a878f7444248d240c159f118ed0c99a 278 Gene3D G3DSA:2.60.200.30 121 254 2.8E-71 T 23-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A3L01_03370 a3246fac0cb9cd39e0d8d8ff98f25b11 125 Gene3D G3DSA:1.10.10.10 12 123 7.6E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_03370 a3246fac0cb9cd39e0d8d8ff98f25b11 125 Pfam PF01022 Bacterial regulatory protein, arsR family 51 96 7.8E-14 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_03370 a3246fac0cb9cd39e0d8d8ff98f25b11 125 SMART SM00418 44 121 2.7E-25 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_03370 a3246fac0cb9cd39e0d8d8ff98f25b11 125 SUPERFAMILY SSF46785 41 120 3.52E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_03370 a3246fac0cb9cd39e0d8d8ff98f25b11 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 78 93 2.0E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_03370 a3246fac0cb9cd39e0d8d8ff98f25b11 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 76 2.0E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_03370 a3246fac0cb9cd39e0d8d8ff98f25b11 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 2.0E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_03370 a3246fac0cb9cd39e0d8d8ff98f25b11 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 93 108 2.0E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_01490 a3363660071832a5c0da0c30cd1d747c 333 TIGRFAM TIGR00341 TIGR00341: TIGR00341 family protein 102 329 9.8E-41 T 23-10-2018 A3L01_01490 a3363660071832a5c0da0c30cd1d747c 333 Pfam PF04087 Domain of unknown function (DUF389) 146 284 9.0E-27 T 23-10-2018 IPR005240 Protein of unknown function DUF389 A3L01_06880 e0765a631648f9e545fec26fb99655fa 200 SUPERFAMILY SSF46785 18 76 8.95E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_06880 e0765a631648f9e545fec26fb99655fa 200 Pfam PF14544 Domain of unknown function (DUF4443) 80 191 4.0E-56 T 23-10-2018 IPR029349 Domain of unknown function DUF4443 A3L01_06880 e0765a631648f9e545fec26fb99655fa 200 Gene3D G3DSA:3.30.1360.30 83 191 7.6E-42 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A3L01_06880 e0765a631648f9e545fec26fb99655fa 200 SUPERFAMILY SSF55261 88 197 4.51E-35 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A3L01_06880 e0765a631648f9e545fec26fb99655fa 200 Gene3D G3DSA:1.10.10.10 1 82 8.9E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_06330 3427dac585c0e52973529fcf3196fb10 161 Pfam PF00011 Hsp20/alpha crystallin family 57 152 9.0E-19 T 23-10-2018 IPR002068 Alpha crystallin/Hsp20 domain A3L01_06330 3427dac585c0e52973529fcf3196fb10 161 SUPERFAMILY SSF49764 44 152 8.64E-32 T 23-10-2018 IPR008978 HSP20-like chaperone A3L01_06330 3427dac585c0e52973529fcf3196fb10 161 Gene3D G3DSA:2.60.40.790 2 160 4.8E-32 T 23-10-2018 IPR008978 HSP20-like chaperone A3L01_08140 07453219c9293a43d70a38573f8c949e 343 Gene3D G3DSA:1.25.40.10 101 334 7.4E-18 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_08140 07453219c9293a43d70a38573f8c949e 343 SUPERFAMILY SSF103473 8 135 2.62E-5 T 23-10-2018 IPR036259 MFS transporter superfamily A3L01_08140 07453219c9293a43d70a38573f8c949e 343 SUPERFAMILY SSF48452 130 323 2.43E-23 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_08140 07453219c9293a43d70a38573f8c949e 343 Pfam PF13174 Tetratricopeptide repeat 159 182 0.024 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L01_08140 07453219c9293a43d70a38573f8c949e 343 Pfam PF13181 Tetratricopeptide repeat 222 248 0.014 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L01_08140 07453219c9293a43d70a38573f8c949e 343 Pfam PF13181 Tetratricopeptide repeat 260 284 0.078 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L01_06865 0c24d43d4dc3ad46532d813e29dc3685 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 291 3.7E-13 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_06865 0c24d43d4dc3ad46532d813e29dc3685 312 SUPERFAMILY SSF161098 55 290 9.16E-38 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_06865 0c24d43d4dc3ad46532d813e29dc3685 312 Gene3D G3DSA:1.10.3720.10 50 303 1.9E-43 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_02140 ea65ed341e5b52d5ea6fbcccbb863f60 67 SUPERFAMILY SSF47113 3 66 3.76E-20 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L01_02140 ea65ed341e5b52d5ea6fbcccbb863f60 67 Gene3D G3DSA:1.10.20.10 1 67 4.4E-25 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L01_02140 ea65ed341e5b52d5ea6fbcccbb863f60 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 65 1.4E-19 T 23-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain A3L01_02140 ea65ed341e5b52d5ea6fbcccbb863f60 67 SMART SM00803 12 66 0.0047 T 23-10-2018 IPR004823 TATA box binding protein associated factor (TAF) GO:0006352 A3L01_08550 5fb7bc3e2059c7fcd71a8a05d3f7bbea 212 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 1 186 27.049 T 23-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 A3L01_08550 5fb7bc3e2059c7fcd71a8a05d3f7bbea 212 Gene3D G3DSA:3.30.1960.10 1 188 3.1E-49 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L01_08550 5fb7bc3e2059c7fcd71a8a05d3f7bbea 212 SUPERFAMILY SSF111278 2 183 4.84E-50 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L01_08550 5fb7bc3e2059c7fcd71a8a05d3f7bbea 212 Pfam PF02676 Methyltransferase TYW3 4 184 5.7E-40 T 23-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L01_08630 6e9da2163f70a9a0f36b331246f1c153 389 Pfam PF01384 Phosphate transporter family 5 378 2.5E-110 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A3L01_06370 bd5e31d420a2e1a38c0897cfa4727ca3 429 Pfam PF00209 Sodium:neurotransmitter symporter family 11 105 1.4E-5 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L01_06370 bd5e31d420a2e1a38c0897cfa4727ca3 429 Pfam PF00209 Sodium:neurotransmitter symporter family 118 364 1.8E-6 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L01_06370 bd5e31d420a2e1a38c0897cfa4727ca3 429 SUPERFAMILY SSF161070 11 365 5.62E-35 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 A3L01_04400 75de1c0f08a48232fed704b08203b250 271 Pfam PF14378 PAP2 superfamily 63 213 7.4E-10 T 23-10-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 A3L01_04400 75de1c0f08a48232fed704b08203b250 271 SUPERFAMILY SSF48317 65 217 2.09E-9 T 23-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily A3L01_04400 75de1c0f08a48232fed704b08203b250 271 Gene3D G3DSA:1.20.144.10 149 235 3.3E-6 T 23-10-2018 A3L01_07245 f8f983ab2ef60d5c2f7e7517267770e2 350 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 110 172 1.9E-4 T 23-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A3L01_07245 f8f983ab2ef60d5c2f7e7517267770e2 350 SUPERFAMILY SSF53901 11 169 4.45E-32 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L01_07245 f8f983ab2ef60d5c2f7e7517267770e2 350 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 223 303 8.5E-10 T 23-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A3L01_07245 f8f983ab2ef60d5c2f7e7517267770e2 350 Gene3D G3DSA:3.40.47.10 9 349 1.5E-69 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L01_07245 f8f983ab2ef60d5c2f7e7517267770e2 350 Hamap MF_01409 UPF0219 protein . 10 350 60.659 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related A3L01_07245 f8f983ab2ef60d5c2f7e7517267770e2 350 TIGRFAM TIGR00748 HMG_CoA_syn_Arc: putative hydroxymethylglutaryl-CoA synthase 11 349 5.8E-192 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related A3L01_07245 f8f983ab2ef60d5c2f7e7517267770e2 350 SUPERFAMILY SSF53901 174 348 6.4E-45 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L01_04855 5fc093311a9fdb47a10cee1b1b72bd24 251 Gene3D G3DSA:3.30.1600.10 29 168 3.0E-91 T 23-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily A3L01_04855 5fc093311a9fdb47a10cee1b1b72bd24 251 Pfam PF02146 Sir2 family 20 198 2.2E-58 T 23-10-2018 IPR003000 Sirtuin family GO:0070403 A3L01_04855 5fc093311a9fdb47a10cee1b1b72bd24 251 Gene3D G3DSA:3.40.50.1220 12 241 3.0E-91 T 23-10-2018 A3L01_04855 5fc093311a9fdb47a10cee1b1b72bd24 251 SUPERFAMILY SSF52467 2 246 6.0E-90 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A3L01_04855 5fc093311a9fdb47a10cee1b1b72bd24 251 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 13 248 60.872 T 23-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 A3L01_07390 1e252a199da51a824c15d21aa309f39c 429 Pfam PF07690 Major Facilitator Superfamily 3 329 1.5E-47 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L01_07390 1e252a199da51a824c15d21aa309f39c 429 Gene3D G3DSA:1.20.1250.20 1 178 5.7E-37 T 23-10-2018 A3L01_07390 1e252a199da51a824c15d21aa309f39c 429 Gene3D G3DSA:1.20.1250.20 195 411 2.8E-23 T 23-10-2018 A3L01_07390 1e252a199da51a824c15d21aa309f39c 429 SUPERFAMILY SSF103473 3 411 1.11E-66 T 23-10-2018 IPR036259 MFS transporter superfamily A3L01_08200 61952ee20b5b74fb5badc9e47bb4a1bf 105 Gene3D G3DSA:3.30.70.20 7 105 4.9E-15 T 23-10-2018 A3L01_08200 61952ee20b5b74fb5badc9e47bb4a1bf 105 Pfam PF14697 4Fe-4S dicluster domain 50 100 8.8E-11 T 23-10-2018 A3L01_08200 61952ee20b5b74fb5badc9e47bb4a1bf 105 SUPERFAMILY SSF54862 30 103 6.14E-23 T 23-10-2018 A3L01_08200 61952ee20b5b74fb5badc9e47bb4a1bf 105 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_08200 61952ee20b5b74fb5badc9e47bb4a1bf 105 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 29 104 1.1E-33 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 A3L01_00440 6fef4751b24ff2a59508d127f392dddb 373 Gene3D G3DSA:2.130.10.10 180 371 2.9E-5 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A3L01_00440 6fef4751b24ff2a59508d127f392dddb 373 SUPERFAMILY SSF50969 49 370 2.04E-12 T 23-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like A3L01_01860 22334dcaa335269a4a30e9edb51c5895 94 ProSitePatterns PS01172 Ribosomal protein L44e signature. 60 71 - T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01860 22334dcaa335269a4a30e9edb51c5895 94 Pfam PF00935 Ribosomal protein L44 16 92 4.7E-26 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01860 22334dcaa335269a4a30e9edb51c5895 94 ProDom PD002841 RIBOSOMAL RIBONUCLEOPROTEIN 60S L44 L44E L41 RESISTANCE 50S ANTIBIOTIC CYCLOHEXIMIDE 9 93 4.0E-40 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01860 22334dcaa335269a4a30e9edb51c5895 94 SUPERFAMILY SSF57829 1 93 2.93E-30 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L01_01860 22334dcaa335269a4a30e9edb51c5895 94 Gene3D G3DSA:3.10.450.80 1 93 3.4E-31 T 23-10-2018 A3L01_01860 22334dcaa335269a4a30e9edb51c5895 94 Hamap MF_01476 50S ribosomal protein L44e [rpl44e]. 1 92 24.954 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_05120 b660d79e53a516231bc8099080eec9cd 339 Gene3D G3DSA:3.40.640.10 44 252 8.1E-98 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L01_05120 b660d79e53a516231bc8099080eec9cd 339 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 333 52.774 T 23-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A3L01_05120 b660d79e53a516231bc8099080eec9cd 339 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 4 331 5.8E-93 T 23-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A3L01_05120 b660d79e53a516231bc8099080eec9cd 339 SUPERFAMILY SSF53383 14 330 3.99E-77 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L01_05120 b660d79e53a516231bc8099080eec9cd 339 Gene3D G3DSA:3.90.1150.10 11 328 8.1E-98 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L01_05120 b660d79e53a516231bc8099080eec9cd 339 Pfam PF00155 Aminotransferase class I and II 23 329 2.3E-48 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L01_05120 b660d79e53a516231bc8099080eec9cd 339 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 202 211 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A3L01_05020 0ff3f69c3f2143996eee6e4b608a0862 100 Gene3D G3DSA:1.20.1260.10 6 75 9.6E-11 T 23-10-2018 IPR012347 Ferritin-like A3L01_05020 0ff3f69c3f2143996eee6e4b608a0862 100 Pfam PF02915 Rubrerythrin 24 80 1.1E-7 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L01_05020 0ff3f69c3f2143996eee6e4b608a0862 100 SUPERFAMILY SSF47240 6 82 2.52E-18 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L01_09500 d054cf69d285937894bbccaf93421f95 286 Gene3D G3DSA:3.30.70.1350 207 282 9.6E-21 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A3L01_09500 d054cf69d285937894bbccaf93421f95 286 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 6 281 6.2E-82 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A3L01_09500 d054cf69d285937894bbccaf93421f95 286 Gene3D G3DSA:1.20.1510.10 4 200 1.2E-62 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A3L01_09500 d054cf69d285937894bbccaf93421f95 286 SUPERFAMILY SSF161111 5 202 8.11E-57 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A3L01_09500 d054cf69d285937894bbccaf93421f95 286 SUPERFAMILY SSF160240 205 280 1.31E-21 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A3L01_09500 d054cf69d285937894bbccaf93421f95 286 Pfam PF16916 Dimerisation domain of Zinc Transporter 208 280 2.6E-22 T 23-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain A3L01_09500 d054cf69d285937894bbccaf93421f95 286 Pfam PF01545 Cation efflux family 8 200 9.0E-46 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A3L01_05330 22af3cbcbd39ffd4bef69b967e80fc94 91 Gene3D G3DSA:3.30.110.20 2 90 1.4E-38 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 A3L01_05330 22af3cbcbd39ffd4bef69b967e80fc94 91 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 4 90 4.7E-46 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 A3L01_05330 22af3cbcbd39ffd4bef69b967e80fc94 91 Pfam PF01918 Alba 6 66 6.4E-22 T 23-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 A3L01_05330 22af3cbcbd39ffd4bef69b967e80fc94 91 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 8 90 2.0E-40 T 23-10-2018 A3L01_05330 22af3cbcbd39ffd4bef69b967e80fc94 91 PIRSF PIRSF028732 1 91 2.5E-40 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 A3L01_05330 22af3cbcbd39ffd4bef69b967e80fc94 91 SUPERFAMILY SSF82704 5 90 3.92E-27 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 A3L01_05330 22af3cbcbd39ffd4bef69b967e80fc94 91 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 1 90 27.952 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 A3L01_07075 5a3c5f64465848d2e49a850c4ba7363e 134 Pfam PF01597 Glycine cleavage H-protein 13 133 5.6E-51 T 23-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate A3L01_07075 5a3c5f64465848d2e49a850c4ba7363e 134 Gene3D G3DSA:2.40.50.100 2 132 3.8E-53 T 23-10-2018 A3L01_07075 5a3c5f64465848d2e49a850c4ba7363e 134 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 11 132 1.7E-46 T 23-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A3L01_07075 5a3c5f64465848d2e49a850c4ba7363e 134 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 54 83 - T 23-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A3L01_07075 5a3c5f64465848d2e49a850c4ba7363e 134 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 10 132 42.103 T 23-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A3L01_07075 5a3c5f64465848d2e49a850c4ba7363e 134 SUPERFAMILY SSF51230 10 133 2.66E-43 T 23-10-2018 IPR011053 Single hybrid motif A3L01_00785 89f9b6e13532e1f5841fc3e78539e3be 260 ProSitePatterns PS00388 Proteasome alpha-type subunits signature. 10 32 - T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L01_00785 89f9b6e13532e1f5841fc3e78539e3be 260 Hamap MF_00289_A Proteasome subunit alpha [prcA]. 5 234 47.852 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 A3L01_00785 89f9b6e13532e1f5841fc3e78539e3be 260 TIGRFAM TIGR03633 arc_protsome_A: proteasome endopeptidase complex, archaeal, alpha subunit 8 234 4.7E-107 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 A3L01_00785 89f9b6e13532e1f5841fc3e78539e3be 260 SUPERFAMILY SSF56235 7 241 2.44E-82 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L01_00785 89f9b6e13532e1f5841fc3e78539e3be 260 Pfam PF10584 Proteasome subunit A N-terminal signature 10 32 4.0E-12 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L01_00785 89f9b6e13532e1f5841fc3e78539e3be 260 Gene3D G3DSA:3.60.20.10 5 253 1.8E-91 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L01_00785 89f9b6e13532e1f5841fc3e78539e3be 260 SMART SM00948 10 32 3.4E-10 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L01_00785 89f9b6e13532e1f5841fc3e78539e3be 260 Pfam PF00227 Proteasome subunit 33 215 5.6E-65 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L01_08910 21c7cca284c8ff67ca71442c04080079 305 SUPERFAMILY SSF46785 155 205 5.84E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_08910 21c7cca284c8ff67ca71442c04080079 305 Pfam PF13412 Winged helix-turn-helix DNA-binding 157 194 3.0E-9 T 23-10-2018 A3L01_08910 21c7cca284c8ff67ca71442c04080079 305 Gene3D G3DSA:1.10.10.10 154 198 1.6E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_00415 b7dfe846341d58e8a8fd3635e889c3c7 554 SUPERFAMILY SSF48371 24 551 3.84E-30 T 23-10-2018 IPR016024 Armadillo-type fold A3L01_00415 b7dfe846341d58e8a8fd3635e889c3c7 554 Gene3D G3DSA:1.25.10.10 352 553 2.5E-14 T 23-10-2018 IPR011989 Armadillo-like helical A3L01_00415 b7dfe846341d58e8a8fd3635e889c3c7 554 Gene3D G3DSA:1.25.10.10 1 253 7.2E-72 T 23-10-2018 IPR011989 Armadillo-like helical A3L01_07965 511ae7bff4c5354219a2481c0511260f 188 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 168 1.6E-25 T 23-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase A3L01_02715 5ce0e4e12912f3a68f40774bd163cb4f 97 Gene3D G3DSA:2.20.28.10 1 97 9.7E-34 T 23-10-2018 A3L01_02715 5ce0e4e12912f3a68f40774bd163cb4f 97 SUPERFAMILY SSF46785 1 95 6.8E-35 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_08425 f0d8e93a482d88d940e1ea82f30fde76 277 Gene3D G3DSA:3.40.50.300 2 241 4.2E-46 T 23-10-2018 A3L01_08425 f0d8e93a482d88d940e1ea82f30fde76 277 SUPERFAMILY SSF52540 4 241 1.45E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_08425 f0d8e93a482d88d940e1ea82f30fde76 277 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 221 4.4E-19 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L01_05550 d2b3adbb0519c1c6a8c3c557c78613d3 217 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 7 30 9.5E-6 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal A3L01_05550 d2b3adbb0519c1c6a8c3c557c78613d3 217 Pfam PF01917 Archaebacterial flagellin 9 196 1.2E-45 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 A3L01_03160 6eb25e8813afc37baf23247eb78579e8 199 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 111 152 1.0E-15 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_03160 6eb25e8813afc37baf23247eb78579e8 199 SUPERFAMILY SSF143243 54 185 8.37E-36 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_03160 6eb25e8813afc37baf23247eb78579e8 199 Gene3D G3DSA:3.30.460.80 9 155 2.1E-27 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_03160 6eb25e8813afc37baf23247eb78579e8 199 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 61 178 8.2E-32 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_08890 6a4de0fe3a143dbb81f922a83e84a2b7 275 SMART SM00729 13 216 1.4E-5 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L01_08890 6a4de0fe3a143dbb81f922a83e84a2b7 275 SUPERFAMILY SSF102114 13 224 4.05E-27 T 23-10-2018 A3L01_08890 6a4de0fe3a143dbb81f922a83e84a2b7 275 Pfam PF04055 Radical SAM superfamily 20 159 3.4E-9 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L01_08890 6a4de0fe3a143dbb81f922a83e84a2b7 275 Gene3D G3DSA:3.20.20.70 5 223 2.6E-15 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_02930 cf0ab5f3f1f326acdb3bb2880bf6f82b 232 Pfam PF09968 Uncharacterized protein domain (DUF2202) 71 230 2.7E-63 T 23-10-2018 IPR019243 Domain of unknown function DUF2202 A3L01_02930 cf0ab5f3f1f326acdb3bb2880bf6f82b 232 Gene3D G3DSA:1.20.1260.10 66 232 9.1E-67 T 23-10-2018 IPR012347 Ferritin-like A3L01_02930 cf0ab5f3f1f326acdb3bb2880bf6f82b 232 SUPERFAMILY SSF47240 70 211 6.34E-16 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L01_08575 7937c61a72f7951032a3603effba8642 311 SUPERFAMILY SSF51556 1 310 5.33E-76 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L01_08575 7937c61a72f7951032a3603effba8642 311 Gene3D G3DSA:3.20.20.140 1 311 4.1E-92 T 23-10-2018 A3L01_08575 7937c61a72f7951032a3603effba8642 311 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 307 4.1E-92 T 23-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 A3L01_00405 29e6221f25e68b34614dbfa153ba721d 203 Gene3D G3DSA:3.40.50.150 1 203 2.7E-61 T 23-10-2018 A3L01_00405 29e6221f25e68b34614dbfa153ba721d 203 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 116 122 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A3L01_00405 29e6221f25e68b34614dbfa153ba721d 203 Pfam PF05175 Methyltransferase small domain 39 128 1.0E-12 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A3L01_00405 29e6221f25e68b34614dbfa153ba721d 203 SUPERFAMILY SSF53335 4 202 1.74E-32 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_02540 fe128bd32fa8ce318dbaf3edd6363ff2 184 SMART SM01118 1 175 1.1E-22 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A3L01_02540 fe128bd32fa8ce318dbaf3edd6363ff2 184 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 1 152 1.0E-62 T 23-10-2018 A3L01_02540 fe128bd32fa8ce318dbaf3edd6363ff2 184 Gene3D G3DSA:2.40.320.10 1 180 1.5E-55 T 23-10-2018 A3L01_02540 fe128bd32fa8ce318dbaf3edd6363ff2 184 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 1 173 2.9E-44 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 A3L01_02540 fe128bd32fa8ce318dbaf3edd6363ff2 184 SUPERFAMILY SSF55154 2 172 1.44E-35 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 A3L01_02540 fe128bd32fa8ce318dbaf3edd6363ff2 184 Pfam PF01928 CYTH domain 1 169 3.7E-34 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A3L01_04450 9d136687c20bf4dac69883aac23be470 330 Pfam PF00586 AIR synthase related protein, N-terminal domain 37 140 9.5E-18 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L01_04450 9d136687c20bf4dac69883aac23be470 330 SUPERFAMILY SSF56042 146 314 2.09E-38 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L01_04450 9d136687c20bf4dac69883aac23be470 330 SUPERFAMILY SSF55326 5 144 5.58E-27 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L01_04450 9d136687c20bf4dac69883aac23be470 330 PIRSF PIRSF005644 2 330 8.9E-92 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A3L01_04450 9d136687c20bf4dac69883aac23be470 330 Pfam PF02769 AIR synthase related protein, C-terminal domain 152 310 1.0E-26 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L01_04450 9d136687c20bf4dac69883aac23be470 330 Gene3D G3DSA:3.90.650.10 146 330 7.1E-52 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L01_04450 9d136687c20bf4dac69883aac23be470 330 Gene3D G3DSA:3.30.1330.10 3 143 1.3E-28 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L01_01965 529f4551dbde2e86bae87994bddd479b 82 ProDom PD005155 RNA POLYMERASE DNA-DIRECTED SUBUNIT NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION II H POLYPEPTIDE 37 79 2.0E-17 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L01_01965 529f4551dbde2e86bae87994bddd479b 82 Pfam PF01191 RNA polymerase Rpb5, C-terminal domain 7 79 9.9E-32 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L01_01965 529f4551dbde2e86bae87994bddd479b 82 Hamap MF_00025 DNA-directed RNA polymerase subunit H [rpoH]. 7 80 23.822 T 23-10-2018 IPR020609 Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L01_01965 529f4551dbde2e86bae87994bddd479b 82 Gene3D G3DSA:3.90.940.20 1 82 1.2E-36 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L01_01965 529f4551dbde2e86bae87994bddd479b 82 SUPERFAMILY SSF55287 7 80 4.97E-28 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L01_01965 529f4551dbde2e86bae87994bddd479b 82 ProSitePatterns PS01110 RNA polymerases H / 23 Kd subunits signature. 12 25 - T 23-10-2018 IPR020608 RNA polymerase, subunit H/Rpb5, conserved site Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L01_07015 de873a0386ae37c02b9aa9628d155d93 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 325 3.7E-31 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L01_07015 de873a0386ae37c02b9aa9628d155d93 326 SMART SM00382 34 247 2.0E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_07015 de873a0386ae37c02b9aa9628d155d93 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 305 4.6E-21 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L01_07015 de873a0386ae37c02b9aa9628d155d93 326 SUPERFAMILY SSF52540 34 323 2.72E-66 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_07015 de873a0386ae37c02b9aa9628d155d93 326 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_07015 de873a0386ae37c02b9aa9628d155d93 326 Pfam PF00005 ABC transporter 26 189 2.0E-25 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_07015 de873a0386ae37c02b9aa9628d155d93 326 Gene3D G3DSA:3.40.50.300 3 326 3.4E-99 T 23-10-2018 A3L01_07760 0b8dc98ebf4654f724ded483f675c7cc 211 Pfam PF13483 Beta-lactamase superfamily domain 2 175 3.2E-29 T 23-10-2018 A3L01_07760 0b8dc98ebf4654f724ded483f675c7cc 211 Gene3D G3DSA:3.60.15.10 1 204 8.9E-50 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_07760 0b8dc98ebf4654f724ded483f675c7cc 211 SUPERFAMILY SSF56281 1 197 1.07E-36 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_07760 0b8dc98ebf4654f724ded483f675c7cc 211 SMART SM00849 7 175 4.5E-18 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_05110 2549c5394f27ead2d53ffba0b67493a2 252 Pfam PF00977 Histidine biosynthesis protein 5 233 7.5E-88 T 23-10-2018 IPR006062 Histidine biosynthesis GO:0000105 A3L01_05110 2549c5394f27ead2d53ffba0b67493a2 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 249 47.679 T 23-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A3L01_05110 2549c5394f27ead2d53ffba0b67493a2 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 249 3.9E-108 T 23-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A3L01_05110 2549c5394f27ead2d53ffba0b67493a2 252 SUPERFAMILY SSF51366 1 249 2.75E-83 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L01_05110 2549c5394f27ead2d53ffba0b67493a2 252 Gene3D G3DSA:3.20.20.70 1 252 8.5E-107 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_08835 2c8f27e2dd4dca468e3dbad04641a29e 401 Gene3D G3DSA:3.40.50.300 45 235 5.8E-10 T 23-10-2018 A3L01_08835 2c8f27e2dd4dca468e3dbad04641a29e 401 SUPERFAMILY SSF52540 60 300 9.36E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_01165 f3bc929f18e6d0aeefb9449a78d9432e 90 Hamap MF_00349 50S ribosomal protein L34e [rpl34e]. 1 86 29.208 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01165 f3bc929f18e6d0aeefb9449a78d9432e 90 ProSitePatterns PS01145 Ribosomal protein L34e signature. 7 20 - T 23-10-2018 IPR018065 Ribosomal protein L34e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01165 f3bc929f18e6d0aeefb9449a78d9432e 90 Gene3D G3DSA:3.40.1800.40 29 86 3.7E-9 T 23-10-2018 IPR038562 Ribosomal protein L34Ae superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01165 f3bc929f18e6d0aeefb9449a78d9432e 90 Pfam PF01199 Ribosomal protein L34e 3 83 7.5E-24 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01165 f3bc929f18e6d0aeefb9449a78d9432e 90 PRINTS PR01250 Ribosomal protein L34 signature 18 35 2.6E-16 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01165 f3bc929f18e6d0aeefb9449a78d9432e 90 PRINTS PR01250 Ribosomal protein L34 signature 56 78 2.6E-16 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01165 f3bc929f18e6d0aeefb9449a78d9432e 90 PRINTS PR01250 Ribosomal protein L34 signature 36 46 2.6E-16 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01165 f3bc929f18e6d0aeefb9449a78d9432e 90 PRINTS PR01250 Ribosomal protein L34 signature 5 18 2.6E-16 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_08195 7f835f3a5195deec73098f4055c2dd45 311 Gene3D G3DSA:3.40.50.970 102 310 8.5E-69 T 23-10-2018 A3L01_08195 7f835f3a5195deec73098f4055c2dd45 311 Gene3D G3DSA:3.40.50.970 12 101 2.1E-6 T 23-10-2018 A3L01_08195 7f835f3a5195deec73098f4055c2dd45 311 SUPERFAMILY SSF52518 17 309 2.13E-72 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L01_08195 7f835f3a5195deec73098f4055c2dd45 311 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 63 218 7.3E-20 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L01_08275 4f8f69c965dc5c61fb2f40665f92dc37 296 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 228 241 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A3L01_08275 4f8f69c965dc5c61fb2f40665f92dc37 296 Pfam PF00294 pfkB family carbohydrate kinase 5 273 3.6E-41 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A3L01_08275 4f8f69c965dc5c61fb2f40665f92dc37 296 SUPERFAMILY SSF53613 1 274 2.03E-63 T 23-10-2018 IPR029056 Ribokinase-like A3L01_08275 4f8f69c965dc5c61fb2f40665f92dc37 296 PRINTS PR00990 Ribokinase signature 8 29 1.8E-6 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L01_08275 4f8f69c965dc5c61fb2f40665f92dc37 296 PRINTS PR00990 Ribokinase signature 105 118 1.8E-6 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L01_08275 4f8f69c965dc5c61fb2f40665f92dc37 296 PRINTS PR00990 Ribokinase signature 166 181 1.8E-6 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L01_08275 4f8f69c965dc5c61fb2f40665f92dc37 296 PRINTS PR00990 Ribokinase signature 198 209 1.8E-6 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L01_08275 4f8f69c965dc5c61fb2f40665f92dc37 296 Gene3D G3DSA:3.40.1190.20 1 285 1.3E-61 T 23-10-2018 IPR029056 Ribokinase-like A3L01_02300 453af13e88ecbdeb6585b1a9cafb8d79 412 Pfam PF09658 CRISPR-associated protein (Cas_Csx9) 23 412 8.5E-213 T 23-10-2018 IPR013488 CRISPR-associated protein Csx9 A3L01_02300 453af13e88ecbdeb6585b1a9cafb8d79 412 TIGRFAM TIGR02671 cas_csx9: CRISPR-associated protein Cas8a2/Csx9, subtype I-A/APERN 23 412 2.9E-202 T 23-10-2018 IPR013488 CRISPR-associated protein Csx9 A3L01_06015 1188e75f7ccbea29c5ba1405da511900 445 SUPERFAMILY SSF52096 7 190 3.78E-31 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L01_06015 1188e75f7ccbea29c5ba1405da511900 445 Pfam PF01957 NfeD-like C-terminal, partner-binding 293 439 6.0E-36 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain A3L01_06015 1188e75f7ccbea29c5ba1405da511900 445 SUPERFAMILY SSF141322 371 440 4.84E-17 T 23-10-2018 A3L01_06015 1188e75f7ccbea29c5ba1405da511900 445 Gene3D G3DSA:2.40.50.140 375 445 6.8E-24 T 23-10-2018 A3L01_06015 1188e75f7ccbea29c5ba1405da511900 445 Gene3D G3DSA:3.90.226.10 19 243 5.1E-69 T 23-10-2018 A3L01_06015 1188e75f7ccbea29c5ba1405da511900 445 Pfam PF00574 Clp protease 52 190 5.5E-11 T 23-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A3L01_05315 fbdc2fd818d667711cc6d60870639052 152 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 10 149 1.8E-27 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A3L01_05315 fbdc2fd818d667711cc6d60870639052 152 Gene3D G3DSA:3.30.479.10 12 150 3.7E-33 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 A3L01_05315 fbdc2fd818d667711cc6d60870639052 152 SUPERFAMILY SSF55620 9 150 1.89E-35 T 23-10-2018 A3L01_02925 9755dbbc2ac450fb45cb1cb49ce3d55f 206 Pfam PF14358 Domain of unknown function (DUF4405) 10 73 2.3E-15 T 23-10-2018 IPR025517 Domain of unknown function DUF4405 A3L01_09305 857fc8b838ba4de7400a0db2a0028158 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 382 399 3.8E-85 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L01_09305 857fc8b838ba4de7400a0db2a0028158 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 449 467 3.8E-85 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L01_09305 857fc8b838ba4de7400a0db2a0028158 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 296 312 3.8E-85 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L01_09305 857fc8b838ba4de7400a0db2a0028158 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 405 426 3.8E-85 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L01_09305 857fc8b838ba4de7400a0db2a0028158 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 249 268 3.8E-85 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L01_09305 857fc8b838ba4de7400a0db2a0028158 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 150 170 3.8E-85 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L01_09305 857fc8b838ba4de7400a0db2a0028158 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 232 248 3.8E-85 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L01_09305 857fc8b838ba4de7400a0db2a0028158 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 269 288 3.8E-85 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L01_09305 857fc8b838ba4de7400a0db2a0028158 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 336 355 3.8E-85 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L01_09305 857fc8b838ba4de7400a0db2a0028158 498 Gene3D G3DSA:1.10.1370.30 1 498 2.1E-194 T 23-10-2018 A3L01_09305 857fc8b838ba4de7400a0db2a0028158 498 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 12 497 1.5E-101 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L01_09305 857fc8b838ba4de7400a0db2a0028158 498 PIRSF PIRSF006615 5 498 4.3E-196 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L01_09305 857fc8b838ba4de7400a0db2a0028158 498 SUPERFAMILY SSF55486 8 498 7.65E-113 T 23-10-2018 A3L01_02825 11e5a2813765d3c8860003cdeb40f397 450 Pfam PF00999 Sodium/hydrogen exchanger family 25 427 5.6E-57 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L01_02825 11e5a2813765d3c8860003cdeb40f397 450 Gene3D G3DSA:1.20.1530.20 16 435 2.2E-23 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L01_00975 276a872500e702dabe1340989143159e 193 SUPERFAMILY SSF52540 9 128 4.88E-11 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_00975 276a872500e702dabe1340989143159e 193 Gene3D G3DSA:3.40.50.300 5 190 1.0E-14 T 23-10-2018 A3L01_00975 276a872500e702dabe1340989143159e 193 Pfam PF00437 Type II/IV secretion system protein 7 111 3.4E-7 T 23-10-2018 IPR001482 Type II/IV secretion system protein A3L01_02625 2587c36c7cacd0b6bed0da5217cf70b7 331 Pfam PF01594 AI-2E family transporter 10 322 2.4E-41 T 23-10-2018 IPR002549 Transmembrane protein TqsA-like A3L01_02530 26624dcc6c635d069870e6dcd60b5936 286 SUPERFAMILY SSF52540 3 240 3.84E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_02530 26624dcc6c635d069870e6dcd60b5936 286 Gene3D G3DSA:3.40.50.300 2 277 4.2E-72 T 23-10-2018 A3L01_02530 26624dcc6c635d069870e6dcd60b5936 286 Pfam PF00005 ABC transporter 21 178 6.8E-25 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_02530 26624dcc6c635d069870e6dcd60b5936 286 SMART SM00382 30 227 1.7E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_02530 26624dcc6c635d069870e6dcd60b5936 286 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_08290 d9aab81f3d7d8a2105351ac4523ec322 103 Gene3D G3DSA:3.30.70.120 1 103 5.7E-36 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A3L01_08290 d9aab81f3d7d8a2105351ac4523ec322 103 SUPERFAMILY SSF54913 2 101 1.15E-33 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A3L01_08290 d9aab81f3d7d8a2105351ac4523ec322 103 Pfam PF03091 CutA1 divalent ion tolerance protein 4 100 4.8E-31 T 23-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 A3L01_06870 c059bb669ad0f471216f3a8657a9eaea 544 SUPERFAMILY SSF53850 56 521 1.83E-44 T 23-10-2018 A3L01_06870 c059bb669ad0f471216f3a8657a9eaea 544 Gene3D G3DSA:3.40.190.10 52 521 6.4E-48 T 23-10-2018 A3L01_06870 c059bb669ad0f471216f3a8657a9eaea 544 Pfam PF01547 Bacterial extracellular solute-binding protein 95 426 1.0E-16 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein A3L01_05870 d6f9104b2b364900347c38565830ecb5 237 PIRSF PIRSF015736 1 237 2.9E-90 T 23-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase A3L01_05870 d6f9104b2b364900347c38565830ecb5 237 Gene3D G3DSA:3.40.50.12500 6 237 4.9E-89 T 23-10-2018 A3L01_05870 d6f9104b2b364900347c38565830ecb5 237 Pfam PF01177 Asp/Glu/Hydantoin racemase 10 215 6.7E-14 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L01_05810 1cefe4207d1d52b0825d9c23473bb0e2 375 Gene3D G3DSA:1.20.1250.20 3 193 1.6E-26 T 23-10-2018 A3L01_05810 1cefe4207d1d52b0825d9c23473bb0e2 375 Pfam PF07690 Major Facilitator Superfamily 14 228 4.1E-25 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L01_05810 1cefe4207d1d52b0825d9c23473bb0e2 375 SUPERFAMILY SSF103473 9 372 6.8E-57 T 23-10-2018 IPR036259 MFS transporter superfamily A3L01_05810 1cefe4207d1d52b0825d9c23473bb0e2 375 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 82 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A3L01_05810 1cefe4207d1d52b0825d9c23473bb0e2 375 Gene3D G3DSA:1.20.1250.20 199 374 3.3E-24 T 23-10-2018 A3L01_09885 7a9b2e8663800d1c30d01017eb7fa421 274 SUPERFAMILY SSF52402 32 203 7.94E-30 T 23-10-2018 A3L01_09885 7a9b2e8663800d1c30d01017eb7fa421 274 Gene3D G3DSA:3.40.50.620 2 195 1.8E-27 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_09885 7a9b2e8663800d1c30d01017eb7fa421 274 PIRSF PIRSF036668 1 273 6.6E-126 T 23-10-2018 IPR012121 ATPase, PP-loop, MJ1599-related A3L01_09885 7a9b2e8663800d1c30d01017eb7fa421 274 Pfam PF01171 PP-loop family 55 160 9.8E-7 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A3L01_04360 4f2e795219baec77cd603b3e3644b753 149 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 97 145 5.9E-14 T 23-10-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain A3L01_04360 4f2e795219baec77cd603b3e3644b753 149 Gene3D G3DSA:2.30.130.90 52 148 1.0E-9 T 23-10-2018 A3L01_04090 60a964939297e4f1602487fc6f4a5a0a 325 Gene3D G3DSA:1.20.58.340 248 325 7.3E-34 T 23-10-2018 A3L01_04090 60a964939297e4f1602487fc6f4a5a0a 325 SUPERFAMILY SSF144083 260 323 1.83E-22 T 23-10-2018 A3L01_04090 60a964939297e4f1602487fc6f4a5a0a 325 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 9 325 9.1E-80 T 23-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 A3L01_04090 60a964939297e4f1602487fc6f4a5a0a 325 Gene3D G3DSA:3.30.460.20 2 135 5.7E-16 T 23-10-2018 A3L01_04090 60a964939297e4f1602487fc6f4a5a0a 325 Gene3D G3DSA:1.20.58.340 136 246 1.4E-29 T 23-10-2018 A3L01_04090 60a964939297e4f1602487fc6f4a5a0a 325 Pfam PF01544 CorA-like Mg2+ transporter protein 38 321 3.3E-64 T 23-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 A3L01_04090 60a964939297e4f1602487fc6f4a5a0a 325 SUPERFAMILY SSF143865 7 258 5.75E-54 T 23-10-2018 A3L01_09855 f7fae42287b2bfaf7c1f88a4252c764a 217 Pfam PF01813 ATP synthase subunit D 13 206 3.8E-61 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L01_09855 f7fae42287b2bfaf7c1f88a4252c764a 217 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 6 209 4.2E-72 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L01_09855 f7fae42287b2bfaf7c1f88a4252c764a 217 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 4 211 25.528 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L01_09575 c2c450b12420d30b4e19a48f577e3474 380 Gene3D G3DSA:1.20.1530.20 1 380 3.0E-98 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L01_09575 c2c450b12420d30b4e19a48f577e3474 380 Pfam PF00999 Sodium/hydrogen exchanger family 9 376 3.2E-67 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L01_06490 1e8cfab110fcbcfe72e3ce9713811c2f 533 Pfam PF01841 Transglutaminase-like superfamily 294 386 1.1E-5 T 23-10-2018 IPR002931 Transglutaminase-like A3L01_06490 1e8cfab110fcbcfe72e3ce9713811c2f 533 Gene3D G3DSA:3.10.620.30 261 401 1.4E-5 T 23-10-2018 A3L01_06490 1e8cfab110fcbcfe72e3ce9713811c2f 533 SUPERFAMILY SSF54001 287 445 5.4E-7 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A3L01_07575 b090f18ebd0e3b8a1b36411c65071367 479 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 18 472 2.3E-217 T 23-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 A3L01_07575 b090f18ebd0e3b8a1b36411c65071367 479 Gene3D G3DSA:3.40.50.720 153 265 4.4E-26 T 23-10-2018 A3L01_07575 b090f18ebd0e3b8a1b36411c65071367 479 SUPERFAMILY SSF46548 9 167 1.1E-31 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L01_07575 b090f18ebd0e3b8a1b36411c65071367 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 178 5.7E-25 T 23-10-2018 A3L01_07575 b090f18ebd0e3b8a1b36411c65071367 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 426 448 5.7E-25 T 23-10-2018 A3L01_07575 b090f18ebd0e3b8a1b36411c65071367 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 297 315 5.7E-25 T 23-10-2018 A3L01_07575 b090f18ebd0e3b8a1b36411c65071367 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 242 260 5.7E-25 T 23-10-2018 A3L01_07575 b090f18ebd0e3b8a1b36411c65071367 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 399 415 5.7E-25 T 23-10-2018 A3L01_07575 b090f18ebd0e3b8a1b36411c65071367 479 Gene3D G3DSA:3.50.50.60 266 407 1.9E-46 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_07575 b090f18ebd0e3b8a1b36411c65071367 479 SUPERFAMILY SSF51971 158 407 1.71E-72 T 23-10-2018 A3L01_07575 b090f18ebd0e3b8a1b36411c65071367 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 441 448 1.7E-17 T 23-10-2018 A3L01_07575 b090f18ebd0e3b8a1b36411c65071367 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 180 1.7E-17 T 23-10-2018 A3L01_07575 b090f18ebd0e3b8a1b36411c65071367 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 400 414 1.7E-17 T 23-10-2018 A3L01_07575 b090f18ebd0e3b8a1b36411c65071367 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 322 1.7E-17 T 23-10-2018 A3L01_07575 b090f18ebd0e3b8a1b36411c65071367 479 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 22 140 1.2E-38 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A3L01_07575 b090f18ebd0e3b8a1b36411c65071367 479 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 158 457 1.2E-42 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L01_07575 b090f18ebd0e3b8a1b36411c65071367 479 Gene3D G3DSA:1.10.1060.10 7 149 1.2E-38 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L01_06405 c901876c5ae953cadafb9cf7b11f0ace 155 Pfam PF01927 Mut7-C RNAse domain 1 145 1.3E-45 T 23-10-2018 IPR002782 Mut7-C RNAse domain A3L01_06405 c901876c5ae953cadafb9cf7b11f0ace 155 SUPERFAMILY SSF88723 19 67 7.19E-5 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L01_10260 dd23e63ec2b6e62a522f5d1256e10332 409 Pfam PF16363 GDP-mannose 4,6 dehydratase 9 397 2.4E-74 T 23-10-2018 IPR016040 NAD(P)-binding domain A3L01_10260 dd23e63ec2b6e62a522f5d1256e10332 409 SUPERFAMILY SSF51735 2 404 5.42E-70 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_04925 371b0116ccedba568581bf42c61090a9 210 SUPERFAMILY SSF55729 12 201 1.36E-26 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L01_04925 371b0116ccedba568581bf42c61090a9 210 Gene3D G3DSA:3.40.630.30 10 209 1.4E-38 T 23-10-2018 A3L01_04925 371b0116ccedba568581bf42c61090a9 210 Pfam PF00583 Acetyltransferase (GNAT) family 35 177 1.9E-19 T 23-10-2018 IPR000182 GNAT domain A3L01_04610 f9f36928d2b5443af5d972978ca5dee7 386 Gene3D G3DSA:1.10.10.10 15 155 5.7E-52 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_04610 f9f36928d2b5443af5d972978ca5dee7 386 Hamap MF_00132 Type 2 DNA topoisomerase 6 subunit A [top6A]. 17 385 40.292 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L01_04610 f9f36928d2b5443af5d972978ca5dee7 386 SUPERFAMILY SSF56726 81 384 4.05E-78 T 23-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L01_04610 f9f36928d2b5443af5d972978ca5dee7 386 Pfam PF04406 Type IIB DNA topoisomerase 83 151 2.0E-19 T 23-10-2018 IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal GO:0003677|GO:0003824|GO:0005524|GO:0005694|GO:0006259 Reactome: R-HSA-912446 A3L01_04610 f9f36928d2b5443af5d972978ca5dee7 386 Gene3D G3DSA:3.40.1360.10 156 385 1.0E-63 T 23-10-2018 A3L01_04610 f9f36928d2b5443af5d972978ca5dee7 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 147 162 6.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L01_04610 f9f36928d2b5443af5d972978ca5dee7 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 226 247 6.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L01_04610 f9f36928d2b5443af5d972978ca5dee7 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 107 118 6.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L01_04610 f9f36928d2b5443af5d972978ca5dee7 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 129 146 6.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L01_04610 f9f36928d2b5443af5d972978ca5dee7 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 202 219 6.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L01_04610 f9f36928d2b5443af5d972978ca5dee7 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 258 274 6.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L01_04610 f9f36928d2b5443af5d972978ca5dee7 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 49 69 1.5E-48 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L01_04610 f9f36928d2b5443af5d972978ca5dee7 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 232 252 1.5E-48 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L01_04610 f9f36928d2b5443af5d972978ca5dee7 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 356 379 1.5E-48 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L01_04610 f9f36928d2b5443af5d972978ca5dee7 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 123 140 1.5E-48 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L01_04610 f9f36928d2b5443af5d972978ca5dee7 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 176 194 1.5E-48 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L01_03205 bd1843ea30060fc30d74c5796855ccdf 84 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 30 81 1.6E-18 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A3L01_03530 b5ff7a8fe4123b5a3223be1e0883f7c0 180 Gene3D G3DSA:3.40.50.300 1 180 1.9E-58 T 23-10-2018 A3L01_03530 b5ff7a8fe4123b5a3223be1e0883f7c0 180 Hamap MF_00039 Putative adenylate kinase. 1 160 24.822 T 23-10-2018 IPR020618 Adenylate kinase isoenzyme 6 GO:0004017|GO:0005524 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L01_03530 b5ff7a8fe4123b5a3223be1e0883f7c0 180 Pfam PF13238 AAA domain 3 116 1.0E-20 T 23-10-2018 A3L01_03530 b5ff7a8fe4123b5a3223be1e0883f7c0 180 SUPERFAMILY SSF52540 1 155 6.75E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_07635 d65faf4a2537ef28edb19f1e3b77616a 302 Pfam PF00953 Glycosyl transferase family 4 69 215 1.2E-33 T 23-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 A3L01_03215 3590cff438eb7c05c0b56629f77765e5 166 SUPERFAMILY SSF55021 106 164 4.3E-8 T 23-10-2018 A3L01_03215 3590cff438eb7c05c0b56629f77765e5 166 PIRSF PIRSF004897 1 166 2.0E-70 T 23-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type A3L01_06235 fd773a493aa014a0ffd32a7b2691c56f 464 SUPERFAMILY SSF52210 301 457 4.84E-32 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L01_06235 fd773a493aa014a0ffd32a7b2691c56f 464 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 158 295 1.4E-55 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L01_06235 fd773a493aa014a0ffd32a7b2691c56f 464 Gene3D G3DSA:3.40.50.720 3 136 1.6E-45 T 23-10-2018 A3L01_06235 fd773a493aa014a0ffd32a7b2691c56f 464 Gene3D G3DSA:3.40.50.261 299 463 2.7E-49 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L01_06235 fd773a493aa014a0ffd32a7b2691c56f 464 Pfam PF13380 CoA binding domain 12 141 1.2E-21 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L01_06235 fd773a493aa014a0ffd32a7b2691c56f 464 SUPERFAMILY SSF52210 138 297 1.13E-44 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L01_06235 fd773a493aa014a0ffd32a7b2691c56f 464 SUPERFAMILY SSF51735 5 136 5.8E-37 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_06235 fd773a493aa014a0ffd32a7b2691c56f 464 TIGRFAM TIGR02717 AcCoA-syn-alpha: acetyl coenzyme A synthetase (ADP forming), alpha domain 5 454 2.1E-185 T 23-10-2018 IPR014089 Acetate-CoA ligase [ADP-forming], alpha domain KEGG: 00010+6.2.1.13|KEGG: 00620+6.2.1.13|KEGG: 00640+6.2.1.13|MetaCyc: PWY-5483|MetaCyc: PWY-5535 A3L01_06235 fd773a493aa014a0ffd32a7b2691c56f 464 SMART SM00881 8 107 5.1E-39 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L01_06235 fd773a493aa014a0ffd32a7b2691c56f 464 Gene3D G3DSA:3.40.50.261 137 298 2.5E-64 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L01_04580 08e0d2b6476f91db2274c33ce257d9de 72 Pfam PF02381 MraZ protein, putative antitoxin-like 8 43 2.9E-5 T 23-10-2018 IPR020603 MraZ domain A3L01_04580 08e0d2b6476f91db2274c33ce257d9de 72 SUPERFAMILY SSF89447 1 53 3.66E-6 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L01_07620 b3e1f12af08dca01e32cf446771970fc 178 Gene3D G3DSA:3.40.140.10 18 166 5.8E-48 T 23-10-2018 A3L01_07620 b3e1f12af08dca01e32cf446771970fc 178 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 21 132 9.4E-29 T 23-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A3L01_07620 b3e1f12af08dca01e32cf446771970fc 178 PIRSF PIRSF006019 12 169 1.0E-56 T 23-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A3L01_07620 b3e1f12af08dca01e32cf446771970fc 178 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 86 121 - T 23-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A3L01_07620 b3e1f12af08dca01e32cf446771970fc 178 SUPERFAMILY SSF53927 22 151 9.79E-40 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A3L01_03110 117fe0483768e92be5e56d2384d73480 158 Gene3D G3DSA:3.30.110.40 1 67 1.1E-6 T 23-10-2018 IPR036868 TusA-like domain superfamily A3L01_03110 117fe0483768e92be5e56d2384d73480 158 Gene3D G3DSA:1.10.3910.10 83 153 4.4E-19 T 23-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily A3L01_03110 117fe0483768e92be5e56d2384d73480 158 SUPERFAMILY SSF140683 87 152 2.62E-17 T 23-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily A3L01_03110 117fe0483768e92be5e56d2384d73480 158 SUPERFAMILY SSF64307 2 67 2.09E-11 T 23-10-2018 IPR036868 TusA-like domain superfamily A3L01_03110 117fe0483768e92be5e56d2384d73480 158 Pfam PF01206 Sulfurtransferase TusA 2 67 8.2E-9 T 23-10-2018 IPR001455 TusA-like domain A3L01_03110 117fe0483768e92be5e56d2384d73480 158 Pfam PF08984 Domain of unknown function (DUF1858) 88 145 1.2E-16 T 23-10-2018 IPR015077 Domain of unknown function DUF1858 A3L01_04415 8964be2659e8dd34923f6a73611934f4 376 Gene3D G3DSA:1.10.8.60 210 291 2.5E-11 T 23-10-2018 A3L01_04415 8964be2659e8dd34923f6a73611934f4 376 SUPERFAMILY SSF52540 22 259 8.3E-29 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_04415 8964be2659e8dd34923f6a73611934f4 376 Gene3D G3DSA:3.40.50.300 6 208 1.2E-26 T 23-10-2018 A3L01_04415 8964be2659e8dd34923f6a73611934f4 376 Pfam PF13173 AAA domain 38 187 2.3E-8 T 23-10-2018 A3L01_04415 8964be2659e8dd34923f6a73611934f4 376 SUPERFAMILY SSF46785 296 370 2.72E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_07030 b264a91e3ff07648e7b18f7790a4b617 727 Gene3D G3DSA:3.90.76.10 245 436 2.6E-23 T 23-10-2018 A3L01_07030 b264a91e3ff07648e7b18f7790a4b617 727 Gene3D G3DSA:3.40.190.10 194 207 1.6E-5 T 23-10-2018 A3L01_07030 b264a91e3ff07648e7b18f7790a4b617 727 Gene3D G3DSA:3.10.105.10 558 723 7.2E-42 T 23-10-2018 A3L01_07030 b264a91e3ff07648e7b18f7790a4b617 727 SUPERFAMILY SSF53850 138 216 1.41E-6 T 23-10-2018 A3L01_07030 b264a91e3ff07648e7b18f7790a4b617 727 SUPERFAMILY SSF53850 234 715 3.03E-85 T 23-10-2018 A3L01_07030 b264a91e3ff07648e7b18f7790a4b617 727 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 281 716 4.1E-68 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain A3L01_07030 b264a91e3ff07648e7b18f7790a4b617 727 Gene3D G3DSA:3.40.190.10 454 555 8.0E-20 T 23-10-2018 A3L01_07030 b264a91e3ff07648e7b18f7790a4b617 727 Gene3D G3DSA:3.10.105.10 128 193 1.6E-5 T 23-10-2018 A3L01_09490 fc9aa7b9f2e34c5c67295b4cc880699e 326 Pfam PF01380 SIS domain 35 153 7.2E-9 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A3L01_09490 fc9aa7b9f2e34c5c67295b4cc880699e 326 Gene3D G3DSA:3.40.50.10490 3 161 9.5E-36 T 23-10-2018 A3L01_09490 fc9aa7b9f2e34c5c67295b4cc880699e 326 SUPERFAMILY SSF53697 4 325 3.75E-56 T 23-10-2018 A3L01_09490 fc9aa7b9f2e34c5c67295b4cc880699e 326 Gene3D G3DSA:3.40.50.10490 164 312 5.6E-43 T 23-10-2018 A3L01_10095 82650461a3f68ace2cbc3175d07084a0 450 Pfam PF00534 Glycosyl transferases group 1 253 420 3.9E-24 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L01_10095 82650461a3f68ace2cbc3175d07084a0 450 Gene3D G3DSA:3.40.50.2000 2 438 1.4E-114 T 23-10-2018 A3L01_10095 82650461a3f68ace2cbc3175d07084a0 450 Pfam PF08323 Starch synthase catalytic domain 2 206 6.4E-36 T 23-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 A3L01_10095 82650461a3f68ace2cbc3175d07084a0 450 Gene3D G3DSA:3.40.50.2000 220 428 1.4E-114 T 23-10-2018 A3L01_10095 82650461a3f68ace2cbc3175d07084a0 450 SUPERFAMILY SSF53756 1 441 8.38E-89 T 23-10-2018 A3L01_06960 c95bcb9cdd18612d69c049ed07551d52 99 Pfam PF09946 Predicted membrane protein (DUF2178) 4 83 1.2E-6 T 23-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane A3L01_00150 a0a017dbeaa2ff3c7ea953fff2c15a5f 251 Pfam PF09874 Predicted membrane protein (DUF2101) 24 228 5.8E-79 T 23-10-2018 IPR018663 Protein of unknown function DUF2101, membrane A3L01_00985 0cc74fde059bbfc46c33c72a8bf8e916 384 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 202 222 - T 23-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A3L01_00985 0cc74fde059bbfc46c33c72a8bf8e916 384 Gene3D G3DSA:3.40.640.10 35 280 2.6E-135 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L01_00985 0cc74fde059bbfc46c33c72a8bf8e916 384 Gene3D G3DSA:3.90.1150.10 25 379 2.6E-135 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L01_00985 0cc74fde059bbfc46c33c72a8bf8e916 384 SUPERFAMILY SSF53383 11 383 2.13E-97 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L01_00985 0cc74fde059bbfc46c33c72a8bf8e916 384 PIRSF PIRSF000524 17 384 9.7E-100 T 23-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 A3L01_00985 0cc74fde059bbfc46c33c72a8bf8e916 384 Pfam PF00266 Aminotransferase class-V 45 370 3.2E-41 T 23-10-2018 IPR000192 Aminotransferase class V domain A3L01_03305 46270333ed3f14b6e559c6452d9dfc13 386 Pfam PF04412 Protein of unknown function (DUF521) 1 382 1.7E-148 T 23-10-2018 IPR007506 Aconitase X catalytic domain, putative A3L01_06465 7526a2d75927b9f206aca8338af9624e 153 Pfam PF00583 Acetyltransferase (GNAT) family 17 127 5.0E-14 T 23-10-2018 IPR000182 GNAT domain A3L01_06465 7526a2d75927b9f206aca8338af9624e 153 SUPERFAMILY SSF55729 10 150 1.62E-23 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L01_06465 7526a2d75927b9f206aca8338af9624e 153 Gene3D G3DSA:3.40.630.30 7 150 8.5E-27 T 23-10-2018 A3L01_09990 6bd8253044bdfa7321efaae83b5ef2ba 249 SUPERFAMILY SSF52540 7 244 1.22E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_09990 6bd8253044bdfa7321efaae83b5ef2ba 249 Gene3D G3DSA:3.40.50.300 2 249 5.8E-74 T 23-10-2018 A3L01_09990 6bd8253044bdfa7321efaae83b5ef2ba 249 Pfam PF06745 KaiC 10 246 1.7E-76 T 23-10-2018 IPR014774 KaiC-like domain A3L01_03645 1f44e1c2a65c1da274e43db5068dd7ae 382 Gene3D G3DSA:3.40.50.970 1 199 1.0E-83 T 23-10-2018 A3L01_03645 1f44e1c2a65c1da274e43db5068dd7ae 382 SUPERFAMILY SSF52922 274 378 3.4E-25 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L01_03645 1f44e1c2a65c1da274e43db5068dd7ae 382 SUPERFAMILY SSF52518 12 264 1.57E-70 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L01_03645 1f44e1c2a65c1da274e43db5068dd7ae 382 Gene3D G3DSA:3.40.50.920 273 381 1.7E-22 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L01_03645 1f44e1c2a65c1da274e43db5068dd7ae 382 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 282 376 3.2E-19 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A3L01_03645 1f44e1c2a65c1da274e43db5068dd7ae 382 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 22 258 3.1E-80 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L01_06455 7765fec5648e7dc6b9367dc4c94c19b1 270 SUPERFAMILY SSF55729 1 136 5.32E-24 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L01_06455 7765fec5648e7dc6b9367dc4c94c19b1 270 Pfam PF00583 Acetyltransferase (GNAT) family 27 126 1.6E-15 T 23-10-2018 IPR000182 GNAT domain A3L01_06455 7765fec5648e7dc6b9367dc4c94c19b1 270 Gene3D G3DSA:3.40.630.30 4 184 3.5E-34 T 23-10-2018 A3L01_05620 99c3b475341b0cbdf92e49f565ee0267 116 SUPERFAMILY SSF88723 5 98 6.73E-15 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L01_05620 99c3b475341b0cbdf92e49f565ee0267 116 Pfam PF01850 PIN domain 10 95 6.9E-6 T 23-10-2018 IPR002716 PIN domain A3L01_05620 99c3b475341b0cbdf92e49f565ee0267 116 Gene3D G3DSA:3.40.50.1010 1 111 1.6E-11 T 23-10-2018 A3L01_00485 110c3b48d7449e4c1d62b9f786491e1c 154 Gene3D G3DSA:3.30.70.920 79 154 1.9E-10 T 23-10-2018 A3L01_00485 110c3b48d7449e4c1d62b9f786491e1c 154 Gene3D G3DSA:1.10.10.10 6 78 1.2E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_00485 110c3b48d7449e4c1d62b9f786491e1c 154 Pfam PF12802 MarR family 7 65 5.6E-9 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A3L01_00485 110c3b48d7449e4c1d62b9f786491e1c 154 Pfam PF01037 Lrp/AsnC ligand binding domain 87 152 9.6E-9 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L01_00485 110c3b48d7449e4c1d62b9f786491e1c 154 SMART SM00419 21 72 4.3E-10 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L01_00485 110c3b48d7449e4c1d62b9f786491e1c 154 SUPERFAMILY SSF46785 31 136 2.14E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_01200 6926f6e53c224512d10f65050ddacabb 149 Gene3D G3DSA:1.10.8.50 1 76 5.5E-26 T 23-10-2018 A3L01_01200 6926f6e53c224512d10f65050ddacabb 149 ProSitePatterns PS00646 Ribosomal protein S13 signature. 117 130 - T 23-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01200 6926f6e53c224512d10f65050ddacabb 149 Gene3D G3DSA:4.10.910.10 88 138 4.3E-20 T 23-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01200 6926f6e53c224512d10f65050ddacabb 149 Pfam PF00416 Ribosomal protein S13/S18 10 137 1.0E-40 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01200 6926f6e53c224512d10f65050ddacabb 149 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 8 148 25.311 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01200 6926f6e53c224512d10f65050ddacabb 149 TIGRFAM TIGR03629 uS13_arch: ribosomal protein uS13 4 148 7.6E-62 T 23-10-2018 IPR019977 Ribosomal protein S13, archaeal GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_01200 6926f6e53c224512d10f65050ddacabb 149 PIRSF PIRSF002134 2 149 4.2E-41 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01200 6926f6e53c224512d10f65050ddacabb 149 SUPERFAMILY SSF46946 9 148 1.55E-34 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A3L01_05170 0dabe805512305dfae525409917fcba5 566 Pfam PF02554 Carbon starvation protein CstA 1 363 2.8E-111 T 23-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 A3L01_05170 0dabe805512305dfae525409917fcba5 566 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 402 520 2.7E-31 T 23-10-2018 IPR025299 CstA, C-terminal domain A3L01_04815 55498eddd8eeed7c1f621309ef76ccc0 440 Pfam PF01523 Putative modulator of DNA gyrase 21 303 2.1E-51 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L01_04815 55498eddd8eeed7c1f621309ef76ccc0 440 SUPERFAMILY SSF111283 2 436 1.28E-94 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L01_04815 55498eddd8eeed7c1f621309ef76ccc0 440 Gene3D G3DSA:3.30.2290.10 3 209 1.5E-16 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L01_06290 60adc269513873bd5adf18dc06dc9b9c 76 SUPERFAMILY SSF160374 1 74 2.09E-24 T 23-10-2018 A3L01_06290 60adc269513873bd5adf18dc06dc9b9c 76 Pfam PF01775 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A 2 58 1.6E-11 T 23-10-2018 IPR023573 Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06290 60adc269513873bd5adf18dc06dc9b9c 76 Gene3D G3DSA:3.10.20.10 3 75 5.1E-26 T 23-10-2018 A3L01_06290 60adc269513873bd5adf18dc06dc9b9c 76 Hamap MF_00273 50S ribosomal protein L18Ae [rpl18a]. 3 58 18.203 T 23-10-2018 IPR028877 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_06290 60adc269513873bd5adf18dc06dc9b9c 76 ProDom PD010302 RIBOSOMAL LX 50S RIBONUCLEOPROTEIN HL32 DIRECT SEQUENCING LXA LSU 6 49 1.0E-11 T 23-10-2018 IPR002768 50S ribosomal protein L18Ae, archaea GO:0003735|GO:0005840|GO:0006412 A3L01_07425 2279f112590de0e363fc0869b83927ea 282 Pfam PF01040 UbiA prenyltransferase family 19 259 2.5E-30 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A3L01_07425 2279f112590de0e363fc0869b83927ea 282 Gene3D G3DSA:1.10.357.140 12 146 3.5E-10 T 23-10-2018 A3L01_05590 dddb9657cc640feeb76dc152938519c4 313 Gene3D G3DSA:1.20.1420.30 35 296 5.5E-82 T 23-10-2018 A3L01_05590 dddb9657cc640feeb76dc152938519c4 313 Gene3D G3DSA:1.20.58.1130 8 195 5.5E-82 T 23-10-2018 A3L01_05590 dddb9657cc640feeb76dc152938519c4 313 Pfam PF01699 Sodium/calcium exchanger protein 165 302 6.5E-25 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A3L01_05590 dddb9657cc640feeb76dc152938519c4 313 Pfam PF01699 Sodium/calcium exchanger protein 5 143 2.5E-25 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A3L01_05590 dddb9657cc640feeb76dc152938519c4 313 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 3 297 2.9E-62 T 23-10-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 A3L01_00330 08bb12e24b7916f7c9b47e9f423cc14b 218 Pfam PF00149 Calcineurin-like phosphoesterase 20 129 1.9E-9 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L01_00330 08bb12e24b7916f7c9b47e9f423cc14b 218 SUPERFAMILY SSF56300 20 156 9.07E-16 T 23-10-2018 A3L01_00330 08bb12e24b7916f7c9b47e9f423cc14b 218 Gene3D G3DSA:3.60.21.10 9 117 7.2E-10 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L01_00330 08bb12e24b7916f7c9b47e9f423cc14b 218 PIRSF PIRSF000887 5 215 3.1E-37 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 A3L01_04800 4b452be634b5c32c75852cf3dc471a09 96 SUPERFAMILY SSF101386 2 79 4.91E-21 T 23-10-2018 A3L01_04800 4b452be634b5c32c75852cf3dc471a09 96 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 23 82 5.0E-14 T 23-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A3L01_04800 4b452be634b5c32c75852cf3dc471a09 96 Gene3D G3DSA:1.10.287.1080 1 79 1.5E-28 T 23-10-2018 A3L01_05195 fb0e136a67d0ab5bafdbd60eb0b6a02a 90 SMART SM00966 6 51 6.1E-11 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L01_05195 fb0e136a67d0ab5bafdbd60eb0b6a02a 90 SUPERFAMILY SSF89447 3 45 6.93E-11 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L01_05195 fb0e136a67d0ab5bafdbd60eb0b6a02a 90 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 44 8.4E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L01_05195 fb0e136a67d0ab5bafdbd60eb0b6a02a 90 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 45 2.8E-11 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L01_05195 fb0e136a67d0ab5bafdbd60eb0b6a02a 90 Gene3D G3DSA:2.10.260.10 5 44 1.7E-9 T 23-10-2018 A3L01_01140 2dd466ac02ae7cfceaac34234b7a7a1e 155 Gene3D G3DSA:3.30.1390.20 5 143 1.3E-55 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily A3L01_01140 2dd466ac02ae7cfceaac34234b7a7a1e 155 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 23-10-2018 IPR018038 Ribosomal protein L30, conserved site A3L01_01140 2dd466ac02ae7cfceaac34234b7a7a1e 155 Gene3D G3DSA:1.10.15.30 60 114 1.3E-55 T 23-10-2018 IPR023106 Ribosomal protein L30, central domain, archaeal type A3L01_01140 2dd466ac02ae7cfceaac34234b7a7a1e 155 Pfam PF00327 Ribosomal protein L30p/L7e 6 54 3.5E-15 T 23-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A3L01_01140 2dd466ac02ae7cfceaac34234b7a7a1e 155 TIGRFAM TIGR01309 uL30_arch: ribosomal protein uL30 4 155 7.2E-62 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 A3L01_01140 2dd466ac02ae7cfceaac34234b7a7a1e 155 SUPERFAMILY SSF55129 5 155 1.57E-48 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily A3L01_01140 2dd466ac02ae7cfceaac34234b7a7a1e 155 Hamap MF_01371_A 50S ribosomal protein L30 [rpmD]. 1 155 81.562 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 A3L01_00710 1c0609c02f414e8d99f0c699885592dc 127 Pfam PF03061 Thioesterase superfamily 40 108 1.6E-8 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A3L01_00710 1c0609c02f414e8d99f0c699885592dc 127 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 19 109 4.7E-11 T 23-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 A3L01_00710 1c0609c02f414e8d99f0c699885592dc 127 Gene3D G3DSA:3.10.129.10 1 127 3.0E-44 T 23-10-2018 A3L01_00710 1c0609c02f414e8d99f0c699885592dc 127 SUPERFAMILY SSF54637 13 118 1.39E-26 T 23-10-2018 IPR029069 HotDog domain superfamily A3L01_07610 1d8e57bec277e0c0620c0b0e2476a23c 121 Gene3D G3DSA:1.10.10.10 19 86 3.4E-13 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_07610 1d8e57bec277e0c0620c0b0e2476a23c 121 SUPERFAMILY SSF46785 17 116 1.01E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_07610 1d8e57bec277e0c0620c0b0e2476a23c 121 Pfam PF03965 Penicillinase repressor 19 111 2.8E-15 T 23-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 A3L01_03575 f7f3c3ccc6e33f860b04ae9f0a780a6a 254 Pfam PF01925 Sulfite exporter TauE/SafE 8 244 7.4E-58 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A3L01_08625 d7ac4c97d238bf694765c7409fcbe8e7 224 Gene3D G3DSA:1.20.58.220 1 224 1.3E-49 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L01_08625 d7ac4c97d238bf694765c7409fcbe8e7 224 SUPERFAMILY SSF109755 26 221 7.72E-18 T 23-10-2018 A3L01_08625 d7ac4c97d238bf694765c7409fcbe8e7 224 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 5 222 9.2E-37 T 23-10-2018 IPR002727 Protein of unknown function DUF47 A3L01_08625 d7ac4c97d238bf694765c7409fcbe8e7 224 Pfam PF01865 Protein of unknown function DUF47 6 222 8.8E-45 T 23-10-2018 IPR018445 Putative phosphate transport regulator A3L01_06920 68ad4936df27a74ac26bd14d9d6b09fd 135 Gene3D G3DSA:3.30.2380.10 5 135 1.8E-44 T 23-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 A3L01_06920 68ad4936df27a74ac26bd14d9d6b09fd 135 SUPERFAMILY SSF143870 9 127 3.27E-23 T 23-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 A3L01_03385 715a0405cfb291a51e1ea2c35d0aa787 266 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 5 103 2.0E-27 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A3L01_03385 715a0405cfb291a51e1ea2c35d0aa787 266 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 138 265 3.0E-41 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A3L01_03385 715a0405cfb291a51e1ea2c35d0aa787 266 Pfam PF10869 Protein of unknown function (DUF2666) 5 116 1.2E-12 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A3L01_03385 715a0405cfb291a51e1ea2c35d0aa787 266 Pfam PF10869 Protein of unknown function (DUF2666) 138 265 5.5E-38 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A3L01_06860 6789cdf421880799449edf685a149606 289 Gene3D G3DSA:1.10.3720.10 5 277 1.1E-44 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_06860 6789cdf421880799449edf685a149606 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 279 6.6E-10 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_06860 6789cdf421880799449edf685a149606 289 SUPERFAMILY SSF161098 9 286 2.62E-47 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_05335 399f72546416d1362af27a09176e8820 218 Pfam PF12840 Helix-turn-helix domain 15 70 4.5E-10 T 23-10-2018 A3L01_05335 399f72546416d1362af27a09176e8820 218 Gene3D G3DSA:1.10.10.10 9 92 1.2E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_05335 399f72546416d1362af27a09176e8820 218 SUPERFAMILY SSF46785 7 96 4.25E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_07755 336cf0e22bd1124828c2bf45c850ff93 125 SMART SM01022 12 100 1.3E-5 T 23-10-2018 IPR007374 ASCH domain A3L01_07755 336cf0e22bd1124828c2bf45c850ff93 125 SUPERFAMILY SSF88697 7 117 6.79E-29 T 23-10-2018 IPR015947 PUA-like superfamily A3L01_07755 336cf0e22bd1124828c2bf45c850ff93 125 Pfam PF04266 ASCH domain 14 101 2.4E-10 T 23-10-2018 IPR007374 ASCH domain A3L01_07755 336cf0e22bd1124828c2bf45c850ff93 125 Gene3D G3DSA:2.30.130.30 9 108 4.4E-32 T 23-10-2018 A3L01_02065 3a518e79181412ddde5ddc7e1be31d16 440 Gene3D G3DSA:1.20.1250.20 223 425 2.6E-24 T 23-10-2018 A3L01_02065 3a518e79181412ddde5ddc7e1be31d16 440 Pfam PF07690 Major Facilitator Superfamily 12 319 1.0E-41 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L01_02065 3a518e79181412ddde5ddc7e1be31d16 440 Gene3D G3DSA:1.20.1250.20 2 196 3.2E-30 T 23-10-2018 A3L01_02065 3a518e79181412ddde5ddc7e1be31d16 440 SUPERFAMILY SSF103473 8 425 1.23E-63 T 23-10-2018 IPR036259 MFS transporter superfamily A3L01_06110 b9b8ebd8053c20076b27dd7b261a988a 319 Gene3D G3DSA:3.40.50.300 43 252 4.2E-88 T 23-10-2018 A3L01_06110 b9b8ebd8053c20076b27dd7b261a988a 319 Pfam PF03308 ArgK protein 18 281 1.7E-102 T 23-10-2018 A3L01_06110 b9b8ebd8053c20076b27dd7b261a988a 319 Gene3D G3DSA:1.20.5.170 1 42 1.1E-5 T 23-10-2018 A3L01_06110 b9b8ebd8053c20076b27dd7b261a988a 319 SMART SM00382 44 194 1.0E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_06110 b9b8ebd8053c20076b27dd7b261a988a 319 SUPERFAMILY SSF52540 2 311 2.5E-81 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06110 b9b8ebd8053c20076b27dd7b261a988a 319 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 12 312 3.9E-128 T 23-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L01_01425 b51e2df3ba0ccdce2be69781d4559a9b 343 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 83 97 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site A3L01_01425 b51e2df3ba0ccdce2be69781d4559a9b 343 Gene3D G3DSA:1.10.600.10 1 343 4.1E-133 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily A3L01_01425 b51e2df3ba0ccdce2be69781d4559a9b 343 Pfam PF00348 Polyprenyl synthetase 33 269 1.1E-69 T 23-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 A3L01_01425 b51e2df3ba0ccdce2be69781d4559a9b 343 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 210 222 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site A3L01_01425 b51e2df3ba0ccdce2be69781d4559a9b 343 SUPERFAMILY SSF48576 4 342 4.68E-96 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily A3L01_08060 4bad9b4a95cbe09a6e84bec7ab81911e 149 Gene3D G3DSA:3.40.50.620 1 149 2.1E-32 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_08060 4bad9b4a95cbe09a6e84bec7ab81911e 149 Pfam PF00582 Universal stress protein family 2 149 2.1E-22 T 23-10-2018 IPR006016 UspA A3L01_08060 4bad9b4a95cbe09a6e84bec7ab81911e 149 SUPERFAMILY SSF52402 2 149 2.43E-28 T 23-10-2018 A3L01_04220 1c3edb9bb29e47f7d4221b62491fee60 171 PIRSF PIRSF006443 1 171 1.7E-58 T 23-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 A3L01_04220 1c3edb9bb29e47f7d4221b62491fee60 171 SMART SM00852 17 165 1.0E-28 T 23-10-2018 IPR001453 MoaB/Mog domain A3L01_04220 1c3edb9bb29e47f7d4221b62491fee60 171 SUPERFAMILY SSF53218 13 168 1.7E-44 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L01_04220 1c3edb9bb29e47f7d4221b62491fee60 171 Gene3D G3DSA:3.40.980.10 12 170 1.8E-47 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L01_04220 1c3edb9bb29e47f7d4221b62491fee60 171 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 159 3.0E-36 T 23-10-2018 IPR001453 MoaB/Mog domain A3L01_04220 1c3edb9bb29e47f7d4221b62491fee60 171 Pfam PF00994 Probable molybdopterin binding domain 17 159 9.3E-36 T 23-10-2018 IPR001453 MoaB/Mog domain A3L01_03520 592944e50f8aee88ec7767b018795057 405 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 21 405 0.0 T 23-10-2018 A3L01_03520 592944e50f8aee88ec7767b018795057 405 Hamap MF_00136 S-adenosylmethionine synthase [mat]. 5 405 52.111 T 23-10-2018 IPR002795 S-adenosylmethionine synthetase, archaea GO:0004478|GO:0005524|GO:0006730 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 A3L01_03520 592944e50f8aee88ec7767b018795057 405 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 6 401 5.5E-180 T 23-10-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 A3L01_03520 592944e50f8aee88ec7767b018795057 405 Gene3D G3DSA:3.30.300.340 18 286 5.5E-171 T 23-10-2018 A3L01_03520 592944e50f8aee88ec7767b018795057 405 Gene3D G3DSA:3.30.300.280 16 398 5.5E-171 T 23-10-2018 A3L01_03520 592944e50f8aee88ec7767b018795057 405 Gene3D G3DSA:3.30.300.10 30 154 5.5E-171 T 23-10-2018 A3L01_00800 ff7db3246d68fd4d2b018a0fa3c56c0f 249 Pfam PF01138 3' exoribonuclease family, domain 1 25 154 1.1E-35 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L01_00800 ff7db3246d68fd4d2b018a0fa3c56c0f 249 Pfam PF03725 3' exoribonuclease family, domain 2 157 222 1.8E-16 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L01_00800 ff7db3246d68fd4d2b018a0fa3c56c0f 249 SUPERFAMILY SSF54211 10 180 3.85E-47 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L01_00800 ff7db3246d68fd4d2b018a0fa3c56c0f 249 TIGRFAM TIGR02065 ECX1: exosome complex exonuclease 1 9 238 3.3E-120 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 A3L01_00800 ff7db3246d68fd4d2b018a0fa3c56c0f 249 Hamap MF_00591 Exosome complex component Rrp41 [rrp41]. 6 242 61.238 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 A3L01_00800 ff7db3246d68fd4d2b018a0fa3c56c0f 249 Gene3D G3DSA:3.30.230.70 24 248 9.8E-78 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L01_00800 ff7db3246d68fd4d2b018a0fa3c56c0f 249 SUPERFAMILY SSF55666 154 240 5.5E-25 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L01_02200 d519da788d8b2f3400acb07c82044071 633 TIGRFAM TIGR00238 TIGR00238: KamA family protein 208 564 2.4E-113 T 23-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase A3L01_02200 d519da788d8b2f3400acb07c82044071 633 Gene3D G3DSA:3.20.20.70 266 566 4.1E-74 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_02200 d519da788d8b2f3400acb07c82044071 633 SUPERFAMILY SSF102114 332 555 6.93E-12 T 23-10-2018 A3L01_01805 55381e4047138ccfbca9d8fcbfa54185 460 Pfam PF00483 Nucleotidyl transferase 2 272 1.3E-59 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L01_01805 55381e4047138ccfbca9d8fcbfa54185 460 Gene3D G3DSA:3.90.550.10 1 341 3.6E-111 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_01805 55381e4047138ccfbca9d8fcbfa54185 460 Gene3D G3DSA:2.60.120.10 345 446 1.6E-18 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L01_01805 55381e4047138ccfbca9d8fcbfa54185 460 Pfam PF01050 Mannose-6-phosphate isomerase 305 455 3.4E-67 T 23-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 A3L01_01805 55381e4047138ccfbca9d8fcbfa54185 460 SUPERFAMILY SSF51182 185 459 7.74E-66 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L01_01805 55381e4047138ccfbca9d8fcbfa54185 460 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 3 458 4.9E-159 T 23-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 A3L01_01805 55381e4047138ccfbca9d8fcbfa54185 460 SUPERFAMILY SSF53448 1 267 1.93E-68 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_01930 249594de3cf77e00f960296f72fcc5d1 215 SUPERFAMILY SSF47973 16 215 3.14E-62 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily A3L01_01930 249594de3cf77e00f960296f72fcc5d1 215 Hamap MF_00480_A 30S ribosomal protein S7 [rpsG]. 15 215 38.168 T 23-10-2018 IPR026018 Ribosomal protein S7, archaeal A3L01_01930 249594de3cf77e00f960296f72fcc5d1 215 Gene3D G3DSA:1.10.455.10 15 215 5.4E-79 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily A3L01_01930 249594de3cf77e00f960296f72fcc5d1 215 TIGRFAM TIGR01028 uS7_euk_arch: ribosomal protein uS7 14 215 2.9E-89 T 23-10-2018 IPR005716 Ribosomal protein S5/S7, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01930 249594de3cf77e00f960296f72fcc5d1 215 PIRSF PIRSF002122 1 215 1.9E-47 T 23-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 A3L01_01930 249594de3cf77e00f960296f72fcc5d1 215 Pfam PF00177 Ribosomal protein S7p/S5e 58 215 4.0E-38 T 23-10-2018 IPR023798 Ribosomal protein S7 domain A3L01_07910 1611724033483c37dc891becc60ca1f5 137 Gene3D G3DSA:2.60.120.460 1 137 5.3E-50 T 23-10-2018 IPR035917 YjbQ-like superfamily A3L01_07910 1611724033483c37dc891becc60ca1f5 137 PIRSF PIRSF004681 1 137 7.8E-39 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L01_07910 1611724033483c37dc891becc60ca1f5 137 Pfam PF01894 Uncharacterised protein family UPF0047 20 134 1.3E-36 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L01_07910 1611724033483c37dc891becc60ca1f5 137 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 11 137 1.8E-39 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L01_07910 1611724033483c37dc891becc60ca1f5 137 SUPERFAMILY SSF111038 1 137 3.4E-44 T 23-10-2018 IPR035917 YjbQ-like superfamily A3L01_03175 5a81bae12f6e16f7c4d128d2d5c00eed 614 Pfam PF00361 Proton-conducting membrane transporter 118 418 5.8E-53 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_05240 57478868739fa2c97ab6fdfe3a0564cf 289 SUPERFAMILY SSF54862 50 123 9.21E-18 T 23-10-2018 A3L01_05240 57478868739fa2c97ab6fdfe3a0564cf 289 Pfam PF13187 4Fe-4S dicluster domain 68 114 1.4E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_05240 57478868739fa2c97ab6fdfe3a0564cf 289 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_05240 57478868739fa2c97ab6fdfe3a0564cf 289 SUPERFAMILY SSF52540 3 284 6.5E-32 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_05240 57478868739fa2c97ab6fdfe3a0564cf 289 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 263 1.7E-20 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L01_05240 57478868739fa2c97ab6fdfe3a0564cf 289 Gene3D G3DSA:3.30.70.20 62 115 1.4E-9 T 23-10-2018 A3L01_03750 cff5e6ad9eca6a13b791a59bd953101d 248 Pfam PF07786 Protein of unknown function (DUF1624) 11 230 8.2E-60 T 23-10-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 A3L01_08570 c9b621be15eb329a3cf9e9ddf99c1355 362 SUPERFAMILY SSF48452 15 189 2.8E-12 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_08570 c9b621be15eb329a3cf9e9ddf99c1355 362 Gene3D G3DSA:1.25.40.10 1 359 4.3E-89 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_09865 7a1354c99b097595e92faf68b0fffcfb 339 SUPERFAMILY SSF161098 117 318 1.5E-6 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_09865 7a1354c99b097595e92faf68b0fffcfb 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 137 330 3.0E-10 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_07290 f59c92b535d729d6bcc4b35eb9c5125e 135 SUPERFAMILY SSF82784 8 133 5.37E-34 T 23-10-2018 IPR036102 OsmC/Ohr superfamily A3L01_07290 f59c92b535d729d6bcc4b35eb9c5125e 135 Pfam PF02566 OsmC-like protein 32 121 5.9E-17 T 23-10-2018 IPR003718 OsmC/Ohr family A3L01_07290 f59c92b535d729d6bcc4b35eb9c5125e 135 Gene3D G3DSA:3.30.300.20 4 134 2.3E-37 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L01_06905 f18886b583fa0f77d0e855c53ceef309 256 Pfam PF13614 AAA domain 4 178 1.8E-54 T 23-10-2018 IPR025669 AAA domain A3L01_06905 f18886b583fa0f77d0e855c53ceef309 256 SUPERFAMILY SSF52540 3 254 7.43E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06905 f18886b583fa0f77d0e855c53ceef309 256 Gene3D G3DSA:3.40.50.300 1 255 2.8E-73 T 23-10-2018 A3L01_06905 f18886b583fa0f77d0e855c53ceef309 256 PIRSF PIRSF009320 92 256 9.7E-6 T 23-10-2018 A3L01_06905 f18886b583fa0f77d0e855c53ceef309 256 PIRSF PIRSF009320 2 47 1.2E-14 T 23-10-2018 A3L01_01340 1c670e656c32609a1af4d5efa61c53c4 433 Gene3D G3DSA:1.25.40.10 3 175 1.5E-15 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_01340 1c670e656c32609a1af4d5efa61c53c4 433 Gene3D G3DSA:1.25.40.10 274 407 1.4E-12 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_06400 197ad259db84a1148aca872976e5e0f5 329 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 306 2.6E-21 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L01_06400 197ad259db84a1148aca872976e5e0f5 329 SUPERFAMILY SSF52540 5 260 1.23E-71 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06400 197ad259db84a1148aca872976e5e0f5 329 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 325 1.1E-30 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L01_06400 197ad259db84a1148aca872976e5e0f5 329 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_06400 197ad259db84a1148aca872976e5e0f5 329 SMART SM00382 45 247 3.6E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_06400 197ad259db84a1148aca872976e5e0f5 329 Gene3D G3DSA:3.40.50.300 3 329 1.3E-99 T 23-10-2018 A3L01_06400 197ad259db84a1148aca872976e5e0f5 329 Pfam PF00005 ABC transporter 37 189 1.7E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_09060 94221ab6974fd98e993e39a23f8da3e9 415 Gene3D G3DSA:3.40.50.300 35 216 7.9E-110 T 23-10-2018 A3L01_09060 94221ab6974fd98e993e39a23f8da3e9 415 SUPERFAMILY SSF46785 297 401 6.17E-31 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_09060 94221ab6974fd98e993e39a23f8da3e9 415 Gene3D G3DSA:1.10.10.10 304 405 1.4E-33 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_09060 94221ab6974fd98e993e39a23f8da3e9 415 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 19 383 1.7E-150 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea A3L01_09060 94221ab6974fd98e993e39a23f8da3e9 415 SMART SM01074 312 393 8.3E-36 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 A3L01_09060 94221ab6974fd98e993e39a23f8da3e9 415 SUPERFAMILY SSF52540 19 291 4.88E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_09060 94221ab6974fd98e993e39a23f8da3e9 415 Hamap MF_01407 ORC1-type DNA replication protein. 12 394 34.215 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea A3L01_09060 94221ab6974fd98e993e39a23f8da3e9 415 Gene3D G3DSA:1.10.8.60 19 295 7.9E-110 T 23-10-2018 A3L01_09060 94221ab6974fd98e993e39a23f8da3e9 415 Pfam PF09079 CDC6, C terminal winged helix domain 312 391 2.1E-26 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 A3L01_09060 94221ab6974fd98e993e39a23f8da3e9 415 SMART SM00382 57 218 5.0E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_09060 94221ab6974fd98e993e39a23f8da3e9 415 Pfam PF13401 AAA domain 58 175 3.4E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_05360 5c81ec9dcb9e5a6cb349882e9cc25fce 481 Gene3D G3DSA:1.20.1720.10 8 198 8.2E-48 T 23-10-2018 A3L01_05360 5c81ec9dcb9e5a6cb349882e9cc25fce 481 SUPERFAMILY SSF103473 5 471 7.72E-69 T 23-10-2018 IPR036259 MFS transporter superfamily A3L01_05360 5c81ec9dcb9e5a6cb349882e9cc25fce 481 Pfam PF07690 Major Facilitator Superfamily 16 406 2.0E-51 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L01_05360 5c81ec9dcb9e5a6cb349882e9cc25fce 481 Gene3D G3DSA:1.20.1250.20 257 463 5.4E-15 T 23-10-2018 A3L01_09570 681f935d3b0143aa91625d2989940254 180 Pfam PF00571 CBS domain 46 95 3.0E-10 T 23-10-2018 IPR000644 CBS domain A3L01_09570 681f935d3b0143aa91625d2989940254 180 Pfam PF00571 CBS domain 121 175 3.5E-15 T 23-10-2018 IPR000644 CBS domain A3L01_09570 681f935d3b0143aa91625d2989940254 180 SUPERFAMILY SSF54631 31 175 7.95E-31 T 23-10-2018 A3L01_09570 681f935d3b0143aa91625d2989940254 180 Gene3D G3DSA:3.10.580.10 107 177 3.3E-17 T 23-10-2018 A3L01_09570 681f935d3b0143aa91625d2989940254 180 SMART SM00116 128 176 1.7E-9 T 23-10-2018 IPR000644 CBS domain A3L01_09570 681f935d3b0143aa91625d2989940254 180 SMART SM00116 50 97 0.0034 T 23-10-2018 IPR000644 CBS domain A3L01_09570 681f935d3b0143aa91625d2989940254 180 Gene3D G3DSA:3.10.580.10 7 98 8.6E-13 T 23-10-2018 A3L01_02615 fd63544106a7ddadc89a548e74e15fa7 334 Gene3D G3DSA:3.40.1750.20 187 253 3.5E-54 T 23-10-2018 A3L01_02615 fd63544106a7ddadc89a548e74e15fa7 334 Gene3D G3DSA:3.90.226.10 91 288 3.5E-54 T 23-10-2018 A3L01_02615 fd63544106a7ddadc89a548e74e15fa7 334 SUPERFAMILY SSF52096 82 281 2.49E-36 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L01_02615 fd63544106a7ddadc89a548e74e15fa7 334 Pfam PF01343 Peptidase family S49 150 296 2.9E-39 T 23-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 A3L01_02615 fd63544106a7ddadc89a548e74e15fa7 334 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 89 292 6.3E-68 T 23-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 A3L01_02340 7a211e8c26b1b6ee562e67775875661b 180 Pfam PF04434 SWIM zinc finger 42 68 9.8E-7 T 23-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 A3L01_01725 cf5686a25704420a34cc458ad1e82519 332 Gene3D G3DSA:1.50.10.150 2 332 2.2E-40 T 23-10-2018 IPR038665 Voltage-dependent anion channel superfamily A3L01_01725 cf5686a25704420a34cc458ad1e82519 332 Pfam PF03595 Voltage-dependent anion channel 6 326 1.0E-67 T 23-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 A3L01_01725 cf5686a25704420a34cc458ad1e82519 332 TIGRFAM TIGR00816 tdt: C4-dicarboxylate transporter/malic acid transport protein 6 331 9.0E-86 T 23-10-2018 IPR011552 Tellurite resistance protein TehA/malic acid transport protein GO:0016021 A3L01_02765 134d830fc09158ea9a6b05bc65c07660 274 ProDom PD039347 PF1398 MJ0538 PH1392 4 253 4.0E-71 T 23-10-2018 IPR020292 Uncharacterised protein family MJ0538 A3L01_05585 8a3d464abe8941c82b2421d68c77f9e6 378 Gene3D G3DSA:3.40.190.10 30 306 2.1E-117 T 23-10-2018 A3L01_05585 8a3d464abe8941c82b2421d68c77f9e6 378 Gene3D G3DSA:3.40.190.10 131 331 2.1E-117 T 23-10-2018 A3L01_05585 8a3d464abe8941c82b2421d68c77f9e6 378 PIRSF PIRSF002825 1 335 7.9E-53 T 23-10-2018 IPR026045 Ferric binding protein A3L01_05585 8a3d464abe8941c82b2421d68c77f9e6 378 Pfam PF13416 Bacterial extracellular solute-binding protein 45 304 4.3E-32 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein A3L01_05585 8a3d464abe8941c82b2421d68c77f9e6 378 SUPERFAMILY SSF53850 24 332 4.83E-81 T 23-10-2018 A3L01_05585 8a3d464abe8941c82b2421d68c77f9e6 378 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 358 377 4.6E-8 T 23-10-2018 IPR027552 CGP-CTERM domain A3L01_05585 8a3d464abe8941c82b2421d68c77f9e6 378 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 25 330 1.4E-97 T 23-10-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030975 A3L01_02275 9b2f76148643b6ca2f2a48e4fe9dcd6b 221 Pfam PF12705 PD-(D/E)XK nuclease superfamily 59 216 9.4E-5 T 23-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type A3L01_02275 9b2f76148643b6ca2f2a48e4fe9dcd6b 221 Gene3D G3DSA:3.90.320.10 7 218 2.5E-18 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal A3L01_00375 138c361a4f7f8567743ceb8081afb2e1 116 Pfam PF03551 Transcriptional regulator PadR-like family 24 97 9.9E-23 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L01_00375 138c361a4f7f8567743ceb8081afb2e1 116 Gene3D G3DSA:1.10.10.10 2 116 8.2E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_00375 138c361a4f7f8567743ceb8081afb2e1 116 SUPERFAMILY SSF46785 13 113 4.4E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_01005 9fefa8deb23af6594d7e1c7eb44ee421 458 Gene3D G3DSA:1.10.10.10 234 303 2.3E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_01005 9fefa8deb23af6594d7e1c7eb44ee421 458 SUPERFAMILY SSF46785 239 314 1.18E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_01005 9fefa8deb23af6594d7e1c7eb44ee421 458 Gene3D G3DSA:3.40.50.300 1 165 6.4E-30 T 23-10-2018 A3L01_01005 9fefa8deb23af6594d7e1c7eb44ee421 458 Pfam PF03008 Archaea bacterial proteins of unknown function 306 401 2.3E-29 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L01_01005 9fefa8deb23af6594d7e1c7eb44ee421 458 SUPERFAMILY SSF52540 4 238 1.3E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_01005 9fefa8deb23af6594d7e1c7eb44ee421 458 Pfam PF01637 ATPase domain predominantly from Archaea 5 200 9.0E-21 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L01_06395 4032a3944831551834d002958527e072 323 SMART SM00382 31 226 2.8E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_06395 4032a3944831551834d002958527e072 323 Gene3D G3DSA:3.40.50.300 1 321 9.6E-96 T 23-10-2018 A3L01_06395 4032a3944831551834d002958527e072 323 Pfam PF00005 ABC transporter 24 177 9.7E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_06395 4032a3944831551834d002958527e072 323 SUPERFAMILY SSF52540 2 248 1.0E-68 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_06395 4032a3944831551834d002958527e072 323 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 226 317 4.0E-24 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L01_06395 4032a3944831551834d002958527e072 323 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 228 288 2.3E-18 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L01_06395 4032a3944831551834d002958527e072 323 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_01755 03149a99f7c28bb4d2ccb408dd66e7af 319 SUPERFAMILY SSF48452 78 219 9.76E-13 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_01755 03149a99f7c28bb4d2ccb408dd66e7af 319 Gene3D G3DSA:1.25.40.10 30 229 7.7E-15 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_01755 03149a99f7c28bb4d2ccb408dd66e7af 319 SMART SM00028 121 154 0.0056 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L01_01755 03149a99f7c28bb4d2ccb408dd66e7af 319 SMART SM00028 81 114 29.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L01_01755 03149a99f7c28bb4d2ccb408dd66e7af 319 Pfam PF13424 Tetratricopeptide repeat 86 153 3.2E-7 T 23-10-2018 A3L01_10295 8077ff866b7c864ee8f2a57c9f8b232f 317 Gene3D G3DSA:3.90.25.10 180 223 5.1E-12 T 23-10-2018 A3L01_10295 8077ff866b7c864ee8f2a57c9f8b232f 317 Gene3D G3DSA:3.90.25.10 224 317 1.5E-27 T 23-10-2018 A3L01_10295 8077ff866b7c864ee8f2a57c9f8b232f 317 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 240 5.3E-56 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A3L01_10295 8077ff866b7c864ee8f2a57c9f8b232f 317 SUPERFAMILY SSF51735 1 315 3.21E-86 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L01_10295 8077ff866b7c864ee8f2a57c9f8b232f 317 Gene3D G3DSA:3.40.50.720 1 179 9.8E-52 T 23-10-2018 A3L01_06495 c7c0450585687e8e6af162b5a89b36a8 178 SUPERFAMILY SSF75217 1 175 2.62E-71 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L01_06495 c7c0450585687e8e6af162b5a89b36a8 178 PIRSF PIRSF016123 1 178 1.8E-87 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A3L01_06495 c7c0450585687e8e6af162b5a89b36a8 178 Gene3D G3DSA:3.40.1280.10 1 178 5.8E-80 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L01_06495 c7c0450585687e8e6af162b5a89b36a8 178 ProDom PD016584 UPF0106 MK0803 MM0086 METAL MA3241 UNCHARACTERIZED DOMAIN TA0931 APE2006 ST0333 54 178 5.0E-56 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A3L01_06495 c7c0450585687e8e6af162b5a89b36a8 178 Hamap MF_00077 tRNA (cytidine(56)-2'-O)-methyltransferase. 1 177 44.982 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A3L01_06495 c7c0450585687e8e6af162b5a89b36a8 178 Pfam PF01994 tRNA ribose 2'-O-methyltransferase, aTrm56 54 175 1.1E-52 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A3L01_04440 e42d64b96a890a0dbfbef5c3b9efe43a 98 Gene3D G3DSA:1.10.10.10 5 96 6.1E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_04440 e42d64b96a890a0dbfbef5c3b9efe43a 98 SUPERFAMILY SSF46785 7 92 1.07E-21 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_04440 e42d64b96a890a0dbfbef5c3b9efe43a 98 SMART SM00418 10 91 1.6E-12 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_04440 e42d64b96a890a0dbfbef5c3b9efe43a 98 Pfam PF12840 Helix-turn-helix domain 11 64 3.7E-14 T 23-10-2018 A3L01_02255 7ce76012603f23a39592541cde0b0431 240 SUPERFAMILY SSF46785 149 194 2.35E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_02255 7ce76012603f23a39592541cde0b0431 240 SMART SM00418 5 86 4.9E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_02255 7ce76012603f23a39592541cde0b0431 240 Gene3D G3DSA:1.10.10.10 2 77 2.6E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_02255 7ce76012603f23a39592541cde0b0431 240 Pfam PF12840 Helix-turn-helix domain 5 59 1.6E-8 T 23-10-2018 A3L01_02255 7ce76012603f23a39592541cde0b0431 240 Gene3D G3DSA:1.10.10.10 164 232 4.2E-35 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_02255 7ce76012603f23a39592541cde0b0431 240 SUPERFAMILY SSF46785 5 101 4.23E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_03845 8c7c1a52767fa013ed13abe83b50e68a 334 Pfam PF12773 Double zinc ribbon 289 330 6.9E-10 T 23-10-2018 IPR025874 Double zinc ribbon A3L01_03845 8c7c1a52767fa013ed13abe83b50e68a 334 SUPERFAMILY SSF117892 75 203 5.1E-13 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily A3L01_03845 8c7c1a52767fa013ed13abe83b50e68a 334 Pfam PF13421 SPFH domain-Band 7 family 16 204 8.1E-36 T 23-10-2018 IPR033880 SPFH domain, YdjI-like A3L01_07145 96492b8f5d4fd4972870ccc6a644bf26 238 Gene3D G3DSA:3.40.50.10310 1 237 5.2E-69 T 23-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 A3L01_07145 96492b8f5d4fd4972870ccc6a644bf26 238 SUPERFAMILY SSF102215 1 235 1.96E-63 T 23-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 A3L01_07145 96492b8f5d4fd4972870ccc6a644bf26 238 Pfam PF02633 Creatinine amidohydrolase 4 234 5.4E-65 T 23-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 A3L01_06460 425a534f61be04b81475c69cf6b4705b 371 SUPERFAMILY SSF51445 61 363 3.3E-55 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L01_06460 425a534f61be04b81475c69cf6b4705b 371 Gene3D G3DSA:3.20.20.80 52 363 1.8E-55 T 23-10-2018 A3L01_06460 425a534f61be04b81475c69cf6b4705b 371 Pfam PF01229 Glycosyl hydrolases family 39 94 208 1.5E-4 T 23-10-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 A3L01_04655 90ae34603f2e7729d47dad166e6b3db5 381 Pfam PF13847 Methyltransferase domain 84 155 1.0E-7 T 23-10-2018 IPR025714 Methyltransferase domain A3L01_04655 90ae34603f2e7729d47dad166e6b3db5 381 Gene3D G3DSA:3.40.50.150 39 234 1.5E-27 T 23-10-2018 A3L01_04655 90ae34603f2e7729d47dad166e6b3db5 381 SUPERFAMILY SSF53335 59 158 1.39E-19 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_09690 ba5287c74e8f2e1c021a069ff172d67c 186 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 8 41 1.1E-9 T 23-10-2018 IPR023833 Signal peptide, camelysin A3L01_09690 ba5287c74e8f2e1c021a069ff172d67c 186 Pfam PF12389 Camelysin metallo-endopeptidase 16 185 2.5E-9 T 23-10-2018 IPR022121 Peptidase M73, camelysin A3L01_04775 fa339295efcfcd1582de25cd07dbf4d6 126 Gene3D G3DSA:3.30.70.120 1 126 9.9E-56 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A3L01_04775 fa339295efcfcd1582de25cd07dbf4d6 126 SUPERFAMILY SSF54913 8 104 3.42E-34 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A3L01_04775 fa339295efcfcd1582de25cd07dbf4d6 126 Pfam PF02641 Uncharacterized ACR, COG1993 11 104 3.6E-38 T 23-10-2018 IPR003793 Domain of unknown function DUF190 A3L01_01730 4e96b3f4c9d0f3e5a78cfa787fe5f9e7 123 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 14 103 1.7E-21 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A3L01_01730 4e96b3f4c9d0f3e5a78cfa787fe5f9e7 123 SUPERFAMILY SSF53146 1 109 4.58E-31 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L01_01730 4e96b3f4c9d0f3e5a78cfa787fe5f9e7 123 Gene3D G3DSA:3.30.420.130 1 104 4.8E-32 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L01_07510 8847ee32b1181920aaf0e85b9170e01f 605 SUPERFAMILY SSF56228 1 209 3.14E-80 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L01_07510 8847ee32b1181920aaf0e85b9170e01f 605 SMART SM00790 4 207 1.6E-129 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L01_07510 8847ee32b1181920aaf0e85b9170e01f 605 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 220 602 8.6E-143 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L01_07510 8847ee32b1181920aaf0e85b9170e01f 605 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 205 1.7E-83 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L01_07510 8847ee32b1181920aaf0e85b9170e01f 605 Gene3D G3DSA:3.60.9.10 1 211 3.4E-95 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L01_07510 8847ee32b1181920aaf0e85b9170e01f 605 SUPERFAMILY SSF48310 211 605 7.19E-142 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L01_07510 8847ee32b1181920aaf0e85b9170e01f 605 Gene3D G3DSA:1.10.599.10 240 602 7.4E-154 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A3L01_07510 8847ee32b1181920aaf0e85b9170e01f 605 Gene3D G3DSA:1.10.569.10 242 428 7.4E-154 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L01_09170 ae2a9f0eb56ee00e4ebcd57b3767338d 101 SUPERFAMILY SSF160363 4 93 1.09E-34 T 23-10-2018 IPR023129 MTH889-like domain superfamily A3L01_09170 ae2a9f0eb56ee00e4ebcd57b3767338d 101 ProDom PD012512 ARCHAEA PH1931 STS176 TA1183 MJ0319 PRECURSOR TVG0378908 UNCHARACTERIZED DUF211 AF1549 12 95 9.0E-39 T 23-10-2018 IPR003831 Protein of unknown function DUF211 A3L01_09170 ae2a9f0eb56ee00e4ebcd57b3767338d 101 Pfam PF02680 Uncharacterized ArCR, COG1888 5 90 6.7E-38 T 23-10-2018 IPR003831 Protein of unknown function DUF211 A3L01_09170 ae2a9f0eb56ee00e4ebcd57b3767338d 101 Gene3D G3DSA:3.30.70.1340 1 86 1.2E-34 T 23-10-2018 IPR023129 MTH889-like domain superfamily A3L01_06245 3d36262c28f4fa73c2b867dd25c0c1b3 146 Pfam PF06146 Phosphate-starvation-inducible E 57 123 5.4E-16 T 23-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like A3L01_08120 a6cd05f5c2cd18f9657665c68a484c0a 215 SUPERFAMILY SSF109755 30 209 4.4E-7 T 23-10-2018 A3L01_08120 a6cd05f5c2cd18f9657665c68a484c0a 215 Pfam PF01865 Protein of unknown function DUF47 7 211 7.9E-43 T 23-10-2018 IPR018445 Putative phosphate transport regulator A3L01_08120 a6cd05f5c2cd18f9657665c68a484c0a 215 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 16 214 5.8E-40 T 23-10-2018 IPR002727 Protein of unknown function DUF47 A3L01_08120 a6cd05f5c2cd18f9657665c68a484c0a 215 Gene3D G3DSA:1.20.58.220 3 212 2.3E-49 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L01_04895 1dc06d6fb57e93b4dbba4a01a91e3e84 215 SUPERFAMILY SSF52833 1 215 1.2E-64 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L01_04895 1dc06d6fb57e93b4dbba4a01a91e3e84 215 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 155 195 2.0E-9 T 23-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L01_04895 1dc06d6fb57e93b4dbba4a01a91e3e84 215 Gene3D G3DSA:3.30.1020.10 145 215 3.5E-33 T 23-10-2018 A3L01_04895 1dc06d6fb57e93b4dbba4a01a91e3e84 215 Gene3D G3DSA:3.40.30.10 1 144 5.5E-46 T 23-10-2018 A3L01_04895 1dc06d6fb57e93b4dbba4a01a91e3e84 215 Pfam PF00578 AhpC/TSA family 4 134 1.1E-32 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L01_04895 1dc06d6fb57e93b4dbba4a01a91e3e84 215 Hamap MF_00401 Peroxiredoxin. 2 215 51.15 T 23-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A3L01_04895 1dc06d6fb57e93b4dbba4a01a91e3e84 215 PIRSF PIRSF000239 1 214 1.5E-70 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L01_05715 aed481efd5378a65b0bc27dbb11f429d 660 Pfam PF00149 Calcineurin-like phosphoesterase 129 366 8.8E-10 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L01_05715 aed481efd5378a65b0bc27dbb11f429d 660 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 640 659 9.4E-6 T 23-10-2018 IPR027552 CGP-CTERM domain A3L01_05715 aed481efd5378a65b0bc27dbb11f429d 660 SUPERFAMILY SSF56300 126 392 1.21E-28 T 23-10-2018 A3L01_05715 aed481efd5378a65b0bc27dbb11f429d 660 Gene3D G3DSA:3.60.21.10 168 374 3.9E-18 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L01_10040 6ad9ef879057893ecbccb0d2a069b657 271 SUPERFAMILY SSF56281 3 251 5.46E-35 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_10040 6ad9ef879057893ecbccb0d2a069b657 271 Gene3D G3DSA:3.60.15.10 1 253 2.3E-29 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L01_10040 6ad9ef879057893ecbccb0d2a069b657 271 Pfam PF12706 Beta-lactamase superfamily domain 32 220 7.2E-24 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L01_03660 a13de4351fdad957662cd62003b8aa5e 396 SUPERFAMILY SSF52922 285 393 6.14E-23 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L01_03660 a13de4351fdad957662cd62003b8aa5e 396 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 34 270 3.2E-76 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L01_03660 a13de4351fdad957662cd62003b8aa5e 396 Gene3D G3DSA:3.40.50.920 283 395 3.7E-22 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L01_03660 a13de4351fdad957662cd62003b8aa5e 396 SUPERFAMILY SSF52518 23 278 2.9E-66 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L01_03660 a13de4351fdad957662cd62003b8aa5e 396 Gene3D G3DSA:3.40.50.970 12 211 2.2E-76 T 23-10-2018 A3L01_03660 a13de4351fdad957662cd62003b8aa5e 396 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 294 388 1.4E-18 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A3L01_06230 4924b1b048779c4cc59c7a83f31c28fd 235 PIRSF PIRSF000883 1 235 8.4E-73 T 23-10-2018 IPR011152 Phosphoesterase MJ0912 A3L01_06230 4924b1b048779c4cc59c7a83f31c28fd 235 Gene3D G3DSA:3.60.21.10 2 235 3.9E-70 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L01_06230 4924b1b048779c4cc59c7a83f31c28fd 235 SUPERFAMILY SSF56300 1 235 1.67E-64 T 23-10-2018 A3L01_06230 4924b1b048779c4cc59c7a83f31c28fd 235 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 196 6.2E-30 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L01_08475 a2645030c6d69491ddc56b2b01914dd9 488 Pfam PF09910 Uncharacterized protein conserved in archaea (DUF2139) 31 362 3.2E-153 T 23-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 A3L01_08475 a2645030c6d69491ddc56b2b01914dd9 488 Gene3D G3DSA:2.130.10.10 13 254 8.0E-6 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A3L01_08475 a2645030c6d69491ddc56b2b01914dd9 488 SUPERFAMILY SSF50998 16 209 2.9E-9 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A3L01_08475 a2645030c6d69491ddc56b2b01914dd9 488 PIRSF PIRSF016666 1 488 5.7E-243 T 23-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 A3L01_09315 6f5662cb9e62ceaa0ad721e1824890f2 116 SUPERFAMILY SSF88697 1 109 8.45E-37 T 23-10-2018 IPR015947 PUA-like superfamily A3L01_09315 6f5662cb9e62ceaa0ad721e1824890f2 116 Pfam PF04266 ASCH domain 6 108 8.0E-18 T 23-10-2018 IPR007374 ASCH domain A3L01_09315 6f5662cb9e62ceaa0ad721e1824890f2 116 Gene3D G3DSA:2.30.130.30 2 109 1.8E-42 T 23-10-2018 A3L01_09315 6f5662cb9e62ceaa0ad721e1824890f2 116 PIRSF PIRSF016134 2 111 2.5E-46 T 23-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 A3L01_09315 6f5662cb9e62ceaa0ad721e1824890f2 116 SMART SM01022 6 109 5.3E-17 T 23-10-2018 IPR007374 ASCH domain A3L01_05970 0edc1725b541488d2898bfc8f0f95c51 333 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 1 309 5.5E-109 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A3L01_05970 0edc1725b541488d2898bfc8f0f95c51 333 SUPERFAMILY SSF50891 174 290 3.45E-12 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A3L01_05970 0edc1725b541488d2898bfc8f0f95c51 333 Gene3D G3DSA:2.40.100.10 172 311 1.5E-50 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A3L01_05970 0edc1725b541488d2898bfc8f0f95c51 333 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 24 283 1.3E-83 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A3L01_05970 0edc1725b541488d2898bfc8f0f95c51 333 SMART SM00797 23 300 2.5E-139 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A3L01_04670 b0b05d8c7391eaef8a2406ea0bf454b1 954 Gene3D G3DSA:2.40.128.390 603 670 4.4E-90 T 23-10-2018 A3L01_04670 b0b05d8c7391eaef8a2406ea0bf454b1 954 Gene3D G3DSA:2.60.40.3020 713 953 6.8E-110 T 23-10-2018 A3L01_04670 b0b05d8c7391eaef8a2406ea0bf454b1 954 Gene3D G3DSA:2.60.40.3030 813 945 6.8E-110 T 23-10-2018 A3L01_04670 b0b05d8c7391eaef8a2406ea0bf454b1 954 Gene3D G3DSA:3.40.50.12610 497 711 4.4E-90 T 23-10-2018 A3L01_09350 d83d90dde846e729b030c1e49cf3fa9f 205 Pfam PF02517 CAAX protease self-immunity 98 190 1.1E-11 T 23-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A3L01_10220 05cf921e1ba9ab9fd20257057a9a26e2 321 Gene3D G3DSA:3.90.550.10 1 242 2.8E-48 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_10220 05cf921e1ba9ab9fd20257057a9a26e2 321 SUPERFAMILY SSF53448 1 261 1.69E-39 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_10220 05cf921e1ba9ab9fd20257057a9a26e2 321 Pfam PF00535 Glycosyl transferase family 2 5 168 6.9E-24 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L01_03155 10536ec45271a57c87f88df1bc18d3ce 394 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 64 75 - T 23-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_03155 10536ec45271a57c87f88df1bc18d3ce 394 Gene3D G3DSA:1.10.645.20 30 394 3.2E-115 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_03155 10536ec45271a57c87f88df1bc18d3ce 394 SUPERFAMILY SSF56762 41 394 5.76E-94 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_03155 10536ec45271a57c87f88df1bc18d3ce 394 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 142 394 5.9E-72 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_08705 716edbebf0d024f8f409ef90d3cc0d8a 512 Pfam PF00361 Proton-conducting membrane transporter 135 435 2.5E-63 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_08705 716edbebf0d024f8f409ef90d3cc0d8a 512 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 74 120 1.8E-11 T 23-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_08705 716edbebf0d024f8f409ef90d3cc0d8a 512 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 223 244 4.1E-16 T 23-10-2018 A3L01_08705 716edbebf0d024f8f409ef90d3cc0d8a 512 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 83 108 4.1E-16 T 23-10-2018 A3L01_08705 716edbebf0d024f8f409ef90d3cc0d8a 512 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 111 131 4.1E-16 T 23-10-2018 A3L01_08705 716edbebf0d024f8f409ef90d3cc0d8a 512 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 318 330 4.1E-16 T 23-10-2018 A3L01_08445 9503d4d346c9f1ebaff7295a902fde38 300 SUPERFAMILY SSF54211 3 155 2.81E-13 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L01_08445 9503d4d346c9f1ebaff7295a902fde38 300 Gene3D G3DSA:3.30.230.10 28 158 5.4E-5 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L01_08445 9503d4d346c9f1ebaff7295a902fde38 300 Pfam PF00288 GHMP kinases N terminal domain 93 151 1.3E-7 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A3L01_08445 9503d4d346c9f1ebaff7295a902fde38 300 PIRSF PIRSF016896 1 295 1.0E-88 T 23-10-2018 IPR012043 Pantoate kinase KEGG: 00770+2.7.1.169|MetaCyc: PWY-6654 A3L01_04900 a8996f786deb9372124123c42a0f4713 234 Pfam PF12698 ABC-2 family transporter protein 46 229 2.5E-9 T 23-10-2018 A3L01_00850 4201fe544ff78288cf730f93e8fa0c7f 152 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 108 125 - T 23-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A3L01_00850 4201fe544ff78288cf730f93e8fa0c7f 152 Gene3D G3DSA:2.40.50.100 78 152 1.5E-29 T 23-10-2018 A3L01_00850 4201fe544ff78288cf730f93e8fa0c7f 152 SUPERFAMILY SSF51230 75 151 1.07E-26 T 23-10-2018 IPR011053 Single hybrid motif A3L01_00850 4201fe544ff78288cf730f93e8fa0c7f 152 Pfam PF00364 Biotin-requiring enzyme 86 151 6.4E-25 T 23-10-2018 IPR000089 Biotin/lipoyl attachment A3L01_08170 10604b94c55fbe7260b6da6d14648e91 436 SUPERFAMILY SSF52540 188 389 1.89E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_08170 10604b94c55fbe7260b6da6d14648e91 436 Pfam PF13167 GTP-binding GTPase N-terminal 17 100 1.0E-23 T 23-10-2018 IPR025121 GTPase HflX, N-terminal A3L01_08170 10604b94c55fbe7260b6da6d14648e91 436 Pfam PF16360 GTP-binding GTPase Middle Region 103 180 6.6E-18 T 23-10-2018 IPR032305 GTP-binding protein, middle domain A3L01_08170 10604b94c55fbe7260b6da6d14648e91 436 Pfam PF01926 50S ribosome-binding GTPase 189 307 8.7E-21 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_08170 10604b94c55fbe7260b6da6d14648e91 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 188 326 1.1E-13 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L01_08170 10604b94c55fbe7260b6da6d14648e91 436 Gene3D G3DSA:3.40.50.300 188 361 8.5E-42 T 23-10-2018 A3L01_08170 10604b94c55fbe7260b6da6d14648e91 436 PIRSF PIRSF006809 1 420 3.8E-121 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 A3L01_08170 10604b94c55fbe7260b6da6d14648e91 436 Hamap MF_00900 GTPase HflX [hflX]. 17 391 42.51 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 A3L01_08170 10604b94c55fbe7260b6da6d14648e91 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 254 272 1.0E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_08170 10604b94c55fbe7260b6da6d14648e91 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 188 208 1.0E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_08170 10604b94c55fbe7260b6da6d14648e91 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 209 227 1.0E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L01_08170 10604b94c55fbe7260b6da6d14648e91 436 Gene3D G3DSA:3.40.50.11060 8 129 1.2E-33 T 23-10-2018 A3L01_08170 10604b94c55fbe7260b6da6d14648e91 436 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 10 356 2.6E-93 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 A3L01_05105 7805f6845fc7ef45e889dd97fd04e2b2 232 Pfam PF00977 Histidine biosynthesis protein 3 217 2.9E-53 T 23-10-2018 IPR006062 Histidine biosynthesis GO:0000105 A3L01_05105 7805f6845fc7ef45e889dd97fd04e2b2 232 Gene3D G3DSA:3.20.20.70 1 228 1.6E-63 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_05105 7805f6845fc7ef45e889dd97fd04e2b2 232 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 225 28.405 T 23-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 A3L01_05105 7805f6845fc7ef45e889dd97fd04e2b2 232 SUPERFAMILY SSF51366 1 224 1.61E-48 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L01_03620 27f863b370cbb3c79593f685f7c05ef3 157 Pfam PF02643 Uncharacterized ACR, COG1430 15 114 8.8E-18 T 23-10-2018 IPR003795 Protein of unknown function DUF192 A3L01_03620 27f863b370cbb3c79593f685f7c05ef3 157 Hamap MF_00263 UPF0127 protein . 2 116 28.561 T 23-10-2018 IPR022906 Uncharacterised protein family UPF0127 A3L01_03620 27f863b370cbb3c79593f685f7c05ef3 157 Gene3D G3DSA:2.60.120.1140 1 123 1.2E-13 T 23-10-2018 IPR038695 Saro_0823-like superfamily A3L01_10000 d25e4a109fdadb31ff1b184d3939b66f 375 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 5 365 7.2E-37 T 23-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane A3L01_08230 bb834f35d02e93809e57841b8a400c93 159 Pfam PF00037 4Fe-4S binding domain 35 52 7.2E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_08230 bb834f35d02e93809e57841b8a400c93 159 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 37 48 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_08230 bb834f35d02e93809e57841b8a400c93 159 SUPERFAMILY SSF54862 34 112 4.89E-15 T 23-10-2018 A3L01_08230 bb834f35d02e93809e57841b8a400c93 159 Gene3D G3DSA:3.30.70.20 31 89 2.5E-12 T 23-10-2018 A3L01_08300 45a065a6c26c833add1858b13cef6ba8 278 Gene3D G3DSA:3.40.50.620 148 278 1.9E-23 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_08300 45a065a6c26c833add1858b13cef6ba8 278 PRINTS PR01438 Universal stress protein signature 236 248 2.1E-17 T 23-10-2018 IPR006015 Universal stress protein A A3L01_08300 45a065a6c26c833add1858b13cef6ba8 278 PRINTS PR01438 Universal stress protein signature 2 20 2.1E-17 T 23-10-2018 IPR006015 Universal stress protein A A3L01_08300 45a065a6c26c833add1858b13cef6ba8 278 PRINTS PR01438 Universal stress protein signature 254 276 2.1E-17 T 23-10-2018 IPR006015 Universal stress protein A A3L01_08300 45a065a6c26c833add1858b13cef6ba8 278 SUPERFAMILY SSF52402 151 276 1.0E-19 T 23-10-2018 A3L01_08300 45a065a6c26c833add1858b13cef6ba8 278 Pfam PF00582 Universal stress protein family 1 133 9.8E-20 T 23-10-2018 IPR006016 UspA A3L01_08300 45a065a6c26c833add1858b13cef6ba8 278 Pfam PF00582 Universal stress protein family 199 276 6.7E-17 T 23-10-2018 IPR006016 UspA A3L01_08300 45a065a6c26c833add1858b13cef6ba8 278 Gene3D G3DSA:3.40.50.620 1 142 1.0E-30 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_08300 45a065a6c26c833add1858b13cef6ba8 278 SUPERFAMILY SSF52402 2 135 1.59E-27 T 23-10-2018 A3L01_01190 85be1c8feda6de8949d0293bc9f083cc 195 Gene3D G3DSA:3.40.50.150 5 193 7.0E-50 T 23-10-2018 A3L01_01190 85be1c8feda6de8949d0293bc9f083cc 195 SUPERFAMILY SSF53335 6 190 3.78E-42 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_01190 85be1c8feda6de8949d0293bc9f083cc 195 Pfam PF05175 Methyltransferase small domain 28 191 3.4E-44 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A3L01_07160 a6044abc69878fc4a4022f79bc49c8bd 47 SUPERFAMILY SSF57667 13 43 5.04E-6 T 23-10-2018 IPR036236 Zinc finger C2H2 superfamily A3L01_07160 a6044abc69878fc4a4022f79bc49c8bd 47 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 20 41 - T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 A3L01_02620 065c8abec91d6876cfe9cbea02561c3f 160 Pfam PF09638 Ph1570 protein 1 156 1.2E-75 T 23-10-2018 IPR023110 PH1570-like domain A3L01_02620 065c8abec91d6876cfe9cbea02561c3f 160 SUPERFAMILY SSF159902 1 156 8.37E-68 T 23-10-2018 A3L01_02620 065c8abec91d6876cfe9cbea02561c3f 160 Gene3D G3DSA:3.40.1600.10 1 156 1.7E-68 T 23-10-2018 IPR036807 PH1570-like superfamily A3L01_06375 c04a41de5a68522d9fea13f4a9fba045 236 Hamap MF_02131 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase [mptE]. 7 224 36.96 T 23-10-2018 IPR027510 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, MptE GO:0003848|GO:0005524 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A3L01_06375 c04a41de5a68522d9fea13f4a9fba045 236 SUPERFAMILY SSF63999 51 139 8.37E-9 T 23-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A3L01_06375 c04a41de5a68522d9fea13f4a9fba045 236 Pfam PF01973 Protein of unknown function DUF115 52 187 5.4E-28 T 23-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like A3L01_06360 7805ed05448a9101a33faafed4118adc 71 SUPERFAMILY SSF50182 6 71 1.09E-28 T 23-10-2018 IPR010920 LSM domain superfamily A3L01_06360 7805ed05448a9101a33faafed4118adc 71 Gene3D G3DSA:2.30.30.100 2 71 3.7E-31 T 23-10-2018 A3L01_02265 eb72c8d234f9aeb370dd5f6f00a7a927 310 SUPERFAMILY SSF53795 105 186 7.32E-5 T 23-10-2018 A3L01_02075 39065334ef30d649f6a39e16051c6025 289 Pfam PF12146 Serine aminopeptidase, S33 66 202 1.2E-13 T 23-10-2018 IPR022742 Serine aminopeptidase, S33 A3L01_02075 39065334ef30d649f6a39e16051c6025 289 Gene3D G3DSA:3.40.50.1820 43 288 1.7E-44 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L01_02075 39065334ef30d649f6a39e16051c6025 289 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 125 155 - T 23-10-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 A3L01_02075 39065334ef30d649f6a39e16051c6025 289 SUPERFAMILY SSF53474 14 288 8.44E-54 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L01_04600 7281c5244c26238f2562cd3840a963bf 136 Gene3D G3DSA:1.10.10.60 85 128 3.0E-7 T 23-10-2018 A3L01_04600 7281c5244c26238f2562cd3840a963bf 136 SUPERFAMILY SSF46689 85 125 4.03E-6 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A3L01_01365 6b1561f0e1a9f63ec92240f73c0a502f 354 SUPERFAMILY SSF53686 2 352 6.02E-76 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L01_01365 6b1561f0e1a9f63ec92240f73c0a502f 354 Gene3D G3DSA:3.40.50.1100 91 186 1.8E-81 T 23-10-2018 A3L01_01365 6b1561f0e1a9f63ec92240f73c0a502f 354 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 75 345 9.5E-61 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L01_01365 6b1561f0e1a9f63ec92240f73c0a502f 354 Gene3D G3DSA:3.40.50.1100 48 350 1.8E-81 T 23-10-2018 A3L01_07125 c53521c8365663fb2fc2fa3ad90ab4e9 382 Pfam PF00999 Sodium/hydrogen exchanger family 8 361 8.1E-27 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L01_07125 c53521c8365663fb2fc2fa3ad90ab4e9 382 Gene3D G3DSA:1.20.1530.20 2 377 5.2E-43 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L01_05520 cb7784d112c9b45cb76f259e5624c919 542 SUPERFAMILY SSF52540 143 522 2.16E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_05520 cb7784d112c9b45cb76f259e5624c919 542 Pfam PF00437 Type II/IV secretion system protein 163 407 2.6E-49 T 23-10-2018 IPR001482 Type II/IV secretion system protein A3L01_05520 cb7784d112c9b45cb76f259e5624c919 542 Gene3D G3DSA:1.10.390.40 83 160 1.6E-59 T 23-10-2018 A3L01_05520 cb7784d112c9b45cb76f259e5624c919 542 Gene3D G3DSA:3.40.50.300 261 538 8.1E-90 T 23-10-2018 A3L01_05520 cb7784d112c9b45cb76f259e5624c919 542 Gene3D G3DSA:3.30.450.370 48 258 1.6E-59 T 23-10-2018 A3L01_07530 c46eefca7d1b0fdc0b4cc88d219f814f 246 SUPERFAMILY SSF52402 50 190 5.67E-13 T 23-10-2018 A3L01_07530 c46eefca7d1b0fdc0b4cc88d219f814f 246 PIRSF PIRSF006601 1 246 4.8E-82 T 23-10-2018 IPR012096 ATPase, PP-loop, MJ1638-related A3L01_07530 c46eefca7d1b0fdc0b4cc88d219f814f 246 Gene3D G3DSA:3.40.50.620 34 191 2.6E-8 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_08735 1008c8f89d8916e52ba0b9fc677723c1 141 SUPERFAMILY SSF54862 27 112 1.2E-22 T 23-10-2018 A3L01_08735 1008c8f89d8916e52ba0b9fc677723c1 141 Gene3D G3DSA:3.30.70.3270 23 141 5.4E-22 T 23-10-2018 A3L01_08735 1008c8f89d8916e52ba0b9fc677723c1 141 Pfam PF12838 4Fe-4S dicluster domain 45 91 4.2E-10 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L01_08735 1008c8f89d8916e52ba0b9fc677723c1 141 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L01_01465 93792a370628209227609483dd115135 122 Gene3D G3DSA:3.40.50.1010 2 122 9.5E-10 T 23-10-2018 A3L01_01465 93792a370628209227609483dd115135 122 SUPERFAMILY SSF88723 1 117 5.89E-14 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L01_01465 93792a370628209227609483dd115135 122 Pfam PF01850 PIN domain 2 111 1.5E-12 T 23-10-2018 IPR002716 PIN domain A3L01_05125 5780db6412c1489667bc1d90eede816d 243 SUPERFAMILY SSF56784 2 206 1.76E-12 T 23-10-2018 IPR036412 HAD-like superfamily A3L01_03285 cd885d602eb1437804f1ca9682701f75 67 Pfam PF04021 Class III signal peptide 8 32 1.6E-6 T 23-10-2018 IPR007166 Class III signal peptide motif A3L01_08790 dc5b1186f4e3ee0cf202ad5b6ad498dd 184 SUPERFAMILY SSF143243 37 163 7.32E-28 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_08790 dc5b1186f4e3ee0cf202ad5b6ad498dd 184 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 106 162 8.0E-12 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_08790 dc5b1186f4e3ee0cf202ad5b6ad498dd 184 Gene3D G3DSA:3.30.460.80 20 145 6.5E-14 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_08790 dc5b1186f4e3ee0cf202ad5b6ad498dd 184 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 46 162 1.4E-21 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_02290 aa3b2ed1833fb1b15168037375425618 220 Gene3D G3DSA:1.10.3210.30 1 179 4.9E-15 T 23-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily A3L01_02290 aa3b2ed1833fb1b15168037375425618 220 Pfam PF01966 HD domain 17 186 4.3E-15 T 23-10-2018 IPR006674 HD domain A3L01_07830 27e1c55fddcbf27cc678b78eee069818 589 Gene3D G3DSA:3.40.50.300 139 292 1.8E-19 T 23-10-2018 A3L01_07830 27e1c55fddcbf27cc678b78eee069818 589 Pfam PF09378 HAS barrel domain 11 113 7.9E-21 T 23-10-2018 IPR018538 Helicase HerA, barrel domain A3L01_07830 27e1c55fddcbf27cc678b78eee069818 589 SUPERFAMILY SSF52540 118 546 2.31E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_07830 27e1c55fddcbf27cc678b78eee069818 589 Pfam PF01935 Domain of unknown function DUF87 153 378 3.0E-49 T 23-10-2018 IPR002789 Helicase HerA, central domain A3L01_06710 9954f30c02b891ad1e4d6e22908d64a1 380 Pfam PF00535 Glycosyl transferase family 2 5 136 3.1E-8 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L01_06710 9954f30c02b891ad1e4d6e22908d64a1 380 SUPERFAMILY SSF53448 3 373 1.97E-71 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_06710 9954f30c02b891ad1e4d6e22908d64a1 380 Gene3D G3DSA:3.90.550.10 1 254 4.3E-43 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_05245 cb63076f5f767ec1740c1ed81bd2327e 136 Gene3D G3DSA:3.30.420.130 2 127 9.1E-15 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L01_05245 cb63076f5f767ec1740c1ed81bd2327e 136 SUPERFAMILY SSF53146 3 117 2.09E-14 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L01_05245 cb63076f5f767ec1740c1ed81bd2327e 136 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 114 7.5E-16 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A3L01_05470 4aad0e78bd46c0999d733ab3bb701c9e 123 Gene3D G3DSA:3.30.1330.30 1 123 7.7E-43 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L01_05470 4aad0e78bd46c0999d733ab3bb701c9e 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 32 46 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A3L01_05470 4aad0e78bd46c0999d733ab3bb701c9e 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 67 77 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A3L01_05470 4aad0e78bd46c0999d733ab3bb701c9e 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 77 91 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A3L01_05470 4aad0e78bd46c0999d733ab3bb701c9e 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 51 64 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A3L01_05470 4aad0e78bd46c0999d733ab3bb701c9e 123 Hamap MF_00326 50S ribosomal protein L7Ae [rpl7ae]. 3 122 35.212 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_05470 4aad0e78bd46c0999d733ab3bb701c9e 123 TIGRFAM TIGR03677 eL8_ribo: ribosomal protein eL8 6 121 2.1E-57 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_05470 4aad0e78bd46c0999d733ab3bb701c9e 123 ProSitePatterns PS01082 Ribosomal protein L7Ae signature. 70 87 - T 23-10-2018 IPR004037 Ribosomal protein L7Ae conserved site GO:0042254|GO:1990904 Reactome: R-HSA-6791226 A3L01_05470 4aad0e78bd46c0999d733ab3bb701c9e 123 PRINTS PR00884 Ribosomal protein HS6 signature 50 61 3.7E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_05470 4aad0e78bd46c0999d733ab3bb701c9e 123 PRINTS PR00884 Ribosomal protein HS6 signature 77 87 3.7E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_05470 4aad0e78bd46c0999d733ab3bb701c9e 123 PRINTS PR00884 Ribosomal protein HS6 signature 6 17 3.7E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_05470 4aad0e78bd46c0999d733ab3bb701c9e 123 PRINTS PR00884 Ribosomal protein HS6 signature 40 50 3.7E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_05470 4aad0e78bd46c0999d733ab3bb701c9e 123 PRINTS PR00884 Ribosomal protein HS6 signature 91 107 3.7E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L01_05470 4aad0e78bd46c0999d733ab3bb701c9e 123 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 18 110 7.6E-32 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 A3L01_05470 4aad0e78bd46c0999d733ab3bb701c9e 123 SUPERFAMILY SSF55315 4 120 5.6E-40 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L01_09215 628966479364da2a304c7f688ddda097 583 PRINTS PR00173 Glutamate-aspartate symporter signature 20 40 8.8E-6 T 23-10-2018 A3L01_09215 628966479364da2a304c7f688ddda097 583 PRINTS PR00173 Glutamate-aspartate symporter signature 112 137 8.8E-6 T 23-10-2018 A3L01_09215 628966479364da2a304c7f688ddda097 583 PRINTS PR00173 Glutamate-aspartate symporter signature 273 292 8.8E-6 T 23-10-2018 A3L01_09215 628966479364da2a304c7f688ddda097 583 PRINTS PR00173 Glutamate-aspartate symporter signature 401 420 8.8E-6 T 23-10-2018 A3L01_09215 628966479364da2a304c7f688ddda097 583 Pfam PF03169 OPT oligopeptide transporter protein 24 575 4.2E-63 T 23-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 A3L01_10235 b98be6c9b46b2a3b9b60e311787d19ba 726 Pfam PF09971 Predicted membrane protein (DUF2206) 350 723 2.6E-47 T 23-10-2018 IPR018701 Protein of unknown function DUF2206, membrane A3L01_04625 3d399f3618c0d58cdaa5bae1af59b25f 258 Pfam PF01163 RIO1 family 65 247 2.9E-53 T 23-10-2018 A3L01_04625 3d399f3618c0d58cdaa5bae1af59b25f 258 SUPERFAMILY SSF56112 54 238 1.68E-20 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A3L01_04625 3d399f3618c0d58cdaa5bae1af59b25f 258 SMART SM00090 23 257 3.0E-114 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A3L01_04625 3d399f3618c0d58cdaa5bae1af59b25f 258 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 191 202 - T 23-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A3L01_04625 3d399f3618c0d58cdaa5bae1af59b25f 258 Gene3D G3DSA:3.30.200.20 51 151 1.8E-12 T 23-10-2018 A3L01_04625 3d399f3618c0d58cdaa5bae1af59b25f 258 Gene3D G3DSA:1.10.510.10 156 257 9.1E-25 T 23-10-2018 A3L01_05405 ae029d32aed2f57ea31bde29513fc2e0 98 Pfam PF11505 Protein of unknown function (DUF3216) 6 97 6.2E-35 T 23-10-2018 IPR023108 Domain of unknown function, DUF3216 A3L01_05405 ae029d32aed2f57ea31bde29513fc2e0 98 Gene3D G3DSA:1.20.120.460 2 98 1.4E-35 T 23-10-2018 IPR038317 Pf1176-like superfamily A3L01_07835 a679a0e504691340de79575f2441688c 436 Gene3D G3DSA:3.60.21.10 1 279 1.9E-123 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L01_07835 a679a0e504691340de79575f2441688c 436 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 240 4.3E-15 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L01_07835 a679a0e504691340de79575f2441688c 436 Hamap MF_02044 DNA double-strand break repair protein Mre11 [mre11]. 1 407 24.226 T 23-10-2018 IPR032885 DNA double-strand break repair protein Mre11, archaea-type GO:0006302 A3L01_07835 a679a0e504691340de79575f2441688c 436 SUPERFAMILY SSF56300 1 336 3.3E-59 T 23-10-2018 A3L01_07835 a679a0e504691340de79575f2441688c 436 Gene3D G3DSA:3.30.110.80 237 333 1.9E-123 T 23-10-2018 A3L01_01695 9668641857d96af9b506afec3a380733 290 SUPERFAMILY SSF55729 4 192 2.1E-23 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L01_01695 9668641857d96af9b506afec3a380733 290 Pfam PF00583 Acetyltransferase (GNAT) family 55 143 2.5E-14 T 23-10-2018 IPR000182 GNAT domain A3L01_01695 9668641857d96af9b506afec3a380733 290 Gene3D G3DSA:3.40.630.30 1 151 1.9E-21 T 23-10-2018 A3L01_05965 34df26c69e5779b4148729489fe06039 144 Pfam PF03684 Uncharacterised protein family (UPF0179) 4 139 1.8E-42 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A3L01_05965 34df26c69e5779b4148729489fe06039 144 Hamap MF_00498 UPF0179 protein . 2 141 23.597 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A3L01_05965 34df26c69e5779b4148729489fe06039 144 PIRSF PIRSF006595 1 144 1.6E-50 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A3L01_05965 34df26c69e5779b4148729489fe06039 144 ProDom PD016182 UPF0179 TK0790 TV1250 PAE0681 PF1381 AF2154 MA3685 VNG1401C MJ1627 PH1477 3 143 8.0E-65 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A3L01_00305 f30e7b67a7992a7b5ec4227a13e5583a 352 SUPERFAMILY SSF53448 2 234 3.56E-47 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_00305 f30e7b67a7992a7b5ec4227a13e5583a 352 Pfam PF04138 GtrA-like protein 236 351 4.8E-27 T 23-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 A3L01_00305 f30e7b67a7992a7b5ec4227a13e5583a 352 Pfam PF00535 Glycosyl transferase family 2 4 167 5.0E-39 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L01_00305 f30e7b67a7992a7b5ec4227a13e5583a 352 Gene3D G3DSA:3.90.550.10 1 240 2.3E-55 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_03355 cf1370847104313560cbcdb75904399b 237 Pfam PF01940 Integral membrane protein DUF92 11 215 9.5E-52 T 23-10-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 A3L01_09790 441243f5c83e836fa0b6c163aef0e0ad 181 TIGRFAM TIGR03879 near_KaiC_dom: probable regulatory domain 29 101 7.1E-26 T 23-10-2018 IPR022285 Conserved hypothetical protein CHP03879, regulatory domain, putative A3L01_09790 441243f5c83e836fa0b6c163aef0e0ad 181 Gene3D G3DSA:1.10.10.60 55 83 6.9E-6 T 23-10-2018 A3L01_03095 642028918ad97b5946a03cca1aa0f928 116 Pfam PF13192 Thioredoxin domain 33 106 1.0E-11 T 23-10-2018 IPR012336 Thioredoxin-like fold A3L01_03095 642028918ad97b5946a03cca1aa0f928 116 SUPERFAMILY SSF52833 26 103 6.77E-16 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L01_03095 642028918ad97b5946a03cca1aa0f928 116 Gene3D G3DSA:3.40.30.10 14 109 1.4E-15 T 23-10-2018 A3L01_01035 98cf2b6a57d0075aa21bfe7f9a12ca9d 255 ProSitePatterns PS00939 Ribosomal protein L1e signature. 106 132 - T 23-10-2018 IPR013000 Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01035 98cf2b6a57d0075aa21bfe7f9a12ca9d 255 SUPERFAMILY SSF52166 1 252 2.62E-73 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 A3L01_01035 98cf2b6a57d0075aa21bfe7f9a12ca9d 255 Hamap MF_01328_A 50S ribosomal protein L4 [rplD]. 2 253 44.692 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 A3L01_01035 98cf2b6a57d0075aa21bfe7f9a12ca9d 255 TIGRFAM TIGR03672 rpl4p_arch: 50S ribosomal protein uL4 1 252 4.8E-117 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 A3L01_01035 98cf2b6a57d0075aa21bfe7f9a12ca9d 255 Pfam PF00573 Ribosomal protein L4/L1 family 16 252 6.4E-50 T 23-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 A3L01_01035 98cf2b6a57d0075aa21bfe7f9a12ca9d 255 Gene3D G3DSA:3.40.1370.10 1 255 3.7E-100 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 A3L01_04810 4c658c5bb4c6cdab7004097640efde3d 472 PIRSF PIRSF004919 1 471 2.9E-152 T 23-10-2018 IPR025502 TldD A3L01_04810 4c658c5bb4c6cdab7004097640efde3d 472 SUPERFAMILY SSF111283 2 467 1.19E-102 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L01_04810 4c658c5bb4c6cdab7004097640efde3d 472 Gene3D G3DSA:3.30.2290.10 1 194 8.1E-26 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L01_04810 4c658c5bb4c6cdab7004097640efde3d 472 Pfam PF01523 Putative modulator of DNA gyrase 18 324 6.8E-56 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L01_10075 a8735a48ecc890f6ab6ab19f9e1c717c 299 SUPERFAMILY SSF160964 7 43 6.54E-7 T 23-10-2018 A3L01_10075 a8735a48ecc890f6ab6ab19f9e1c717c 299 SUPERFAMILY SSF161098 58 284 7.72E-49 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_10075 a8735a48ecc890f6ab6ab19f9e1c717c 299 Gene3D G3DSA:1.10.3720.10 54 296 7.3E-57 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_10075 a8735a48ecc890f6ab6ab19f9e1c717c 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 284 7.1E-17 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_00900 9b7187a2ed0cbb097390032863f5e7a1 281 ProDom PD038341 HYDROLASE COFACTOR MOLYBDENUM BIOSYNTHESIS METAL-DEPENDENT DEOXYRIBONUCLEASE PREDICTED TATD-RELATED TVG0313409 A 114 280 4.0E-82 T 23-10-2018 A3L01_00900 9b7187a2ed0cbb097390032863f5e7a1 281 SUPERFAMILY SSF51556 1 278 3.0E-32 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L01_00900 9b7187a2ed0cbb097390032863f5e7a1 281 Gene3D G3DSA:3.20.20.140 3 280 2.2E-26 T 23-10-2018 A3L01_00900 9b7187a2ed0cbb097390032863f5e7a1 281 Pfam PF01026 TatD related DNase 5 275 9.5E-30 T 23-10-2018 IPR001130 TatD family GO:0016788 A3L01_00900 9b7187a2ed0cbb097390032863f5e7a1 281 PIRSF PIRSF004961 1 281 5.5E-123 T 23-10-2018 IPR011589 Protein of unknown function UCP004961 A3L01_06760 714b2684d87e40ceeb5a59626ac0738f 621 SUPERFAMILY SSF48208 220 585 1.21E-59 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A3L01_06760 714b2684d87e40ceeb5a59626ac0738f 621 Pfam PF06202 Amylo-alpha-1,6-glucosidase 227 570 8.6E-10 T 23-10-2018 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 A3L01_06760 714b2684d87e40ceeb5a59626ac0738f 621 Gene3D G3DSA:1.50.10.10 218 577 8.0E-36 T 23-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A3L01_06760 714b2684d87e40ceeb5a59626ac0738f 621 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 8 148 5.1E-13 T 23-10-2018 IPR032856 Putative glycogen debranching enzyme, N-terminal A3L01_08940 149a0a3e9329e2edbcb38b3683a0ae9f 171 Hamap MF_01117 CDP-archaeol synthase [carS]. 14 171 28.144 T 23-10-2018 IPR002726 CDP-archaeol synthase, archaea KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 A3L01_08940 149a0a3e9329e2edbcb38b3683a0ae9f 171 Pfam PF01864 CDP-archaeol synthase 7 171 2.3E-57 T 23-10-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 A3L01_00825 e5b4ce2e16ad3851a58306ce01944697 174 Pfam PF04266 ASCH domain 6 116 2.2E-6 T 23-10-2018 IPR007374 ASCH domain A3L01_00825 e5b4ce2e16ad3851a58306ce01944697 174 SUPERFAMILY SSF88697 3 145 1.18E-16 T 23-10-2018 IPR015947 PUA-like superfamily A3L01_00825 e5b4ce2e16ad3851a58306ce01944697 174 SMART SM01022 5 125 8.3E-5 T 23-10-2018 IPR007374 ASCH domain A3L01_03495 be0b2b5b1f2a1d87f6b970a632c9ae91 69 Pfam PF05239 PRC-barrel domain 2 68 1.8E-13 T 23-10-2018 IPR027275 PRC-barrel domain A3L01_03495 be0b2b5b1f2a1d87f6b970a632c9ae91 69 SUPERFAMILY SSF50346 1 66 4.87E-15 T 23-10-2018 IPR011033 PRC-barrel-like superfamily A3L01_03495 be0b2b5b1f2a1d87f6b970a632c9ae91 69 Gene3D G3DSA:2.30.30.240 3 69 4.5E-7 T 23-10-2018 A3L01_03070 ebaf099e7c02507bcb4d6099a88fe030 155 SUPERFAMILY SSF49777 7 154 1.31E-45 T 23-10-2018 IPR036610 PEBP-like superfamily A3L01_03070 ebaf099e7c02507bcb4d6099a88fe030 155 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 20 152 1.4E-41 T 23-10-2018 IPR005247 YbhB/YbcL A3L01_03070 ebaf099e7c02507bcb4d6099a88fe030 155 Gene3D G3DSA:3.90.280.10 5 155 6.1E-51 T 23-10-2018 IPR036610 PEBP-like superfamily A3L01_03070 ebaf099e7c02507bcb4d6099a88fe030 155 Pfam PF01161 Phosphatidylethanolamine-binding protein 15 152 5.2E-34 T 23-10-2018 IPR008914 Phosphatidylethanolamine-binding protein A3L01_05035 6f3ca77fac6094870b201fd8778ba060 159 SUPERFAMILY SSF47240 1 147 3.25E-27 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L01_05035 6f3ca77fac6094870b201fd8778ba060 159 Pfam PF02915 Rubrerythrin 5 138 6.5E-15 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L01_05035 6f3ca77fac6094870b201fd8778ba060 159 Gene3D G3DSA:1.20.1260.10 1 143 1.1E-25 T 23-10-2018 IPR012347 Ferritin-like A3L01_03720 b75eba52654b3a999d8f9c132f6b2e69 602 Pfam PF16286 Domain of unknown function (DUF4932) 31 167 3.1E-11 T 23-10-2018 IPR032560 Protein of unknown function DUF4932 A3L01_03720 b75eba52654b3a999d8f9c132f6b2e69 602 Pfam PF05124 S-layer like family, C-terminal region 435 570 4.6E-9 T 23-10-2018 IPR022651 S-layer protein, C-terminal A3L01_01440 5f0d0f053094e49c81ce4d43a57c05a5 224 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 12 216 3.4E-60 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L01_01440 5f0d0f053094e49c81ce4d43a57c05a5 224 Gene3D G3DSA:3.40.50.11570 7 221 6.3E-53 T 23-10-2018 A3L01_02605 d8e5a7fcb2465fbcafd6847b732c656f 128 Pfam PF11469 Ribonuclease III 10 127 7.7E-59 T 23-10-2018 IPR021568 Ribonuclease III, archaeal A3L01_02605 d8e5a7fcb2465fbcafd6847b732c656f 128 SUPERFAMILY SSF69065 7 127 3.66E-50 T 23-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 A3L01_02605 d8e5a7fcb2465fbcafd6847b732c656f 128 Gene3D G3DSA:1.10.1520.20 2 127 1.0E-46 T 23-10-2018 IPR038133 Ribonuclease III superfamily, archaeal A3L01_07195 a956043f7d5d4cd1a873b22a6a3bb6d4 336 Pfam PF00850 Histone deacetylase domain 20 290 1.1E-65 T 23-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A3L01_07195 a956043f7d5d4cd1a873b22a6a3bb6d4 336 Gene3D G3DSA:3.40.800.20 5 317 4.4E-81 T 23-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A3L01_07195 a956043f7d5d4cd1a873b22a6a3bb6d4 336 SUPERFAMILY SSF52768 3 335 1.2E-87 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily A3L01_07195 a956043f7d5d4cd1a873b22a6a3bb6d4 336 PRINTS PR01270 Histone deacetylase superfamily signature 241 251 7.4E-11 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A3L01_07195 a956043f7d5d4cd1a873b22a6a3bb6d4 336 PRINTS PR01270 Histone deacetylase superfamily signature 157 172 7.4E-11 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A3L01_07195 a956043f7d5d4cd1a873b22a6a3bb6d4 336 PRINTS PR01270 Histone deacetylase superfamily signature 125 148 7.4E-11 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A3L01_08590 8fa5d9ec4f492802eae187fca6739892 440 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 8 415 2.7E-50 T 23-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane A3L01_08670 b0c52855c4a4a13d0cd99d60e00ff72f 166 Pfam PF01899 Na+/H+ ion antiporter subunit 7 163 1.2E-43 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L01_08670 b0c52855c4a4a13d0cd99d60e00ff72f 166 PIRSF PIRSF019239 1 165 7.6E-41 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L01_05640 ba426d693b2c928f2f0c52861d0c2d88 343 SUPERFAMILY SSF52317 36 230 9.38E-11 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_03865 c89cc58105e51dfbc8ddb229da28d09a 857 SUPERFAMILY SSF103647 345 484 1.57E-5 T 23-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 A3L01_00280 bcb8c3a6452d084b66c3d09b0edca576 216 Pfam PF06510 Protein of unknown function (DUF1102) 39 198 2.7E-45 T 23-10-2018 IPR009482 Protein of unknown function DUF1102 A3L01_03020 c16813336f140eab20259aa5a8703388 253 Pfam PF04055 Radical SAM superfamily 31 183 2.7E-12 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L01_03020 c16813336f140eab20259aa5a8703388 253 Pfam PF13394 4Fe-4S single cluster domain 29 110 3.5E-6 T 23-10-2018 A3L01_03020 c16813336f140eab20259aa5a8703388 253 Gene3D G3DSA:3.20.20.70 4 253 2.4E-25 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_03020 c16813336f140eab20259aa5a8703388 253 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 253 36.747 T 23-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 A3L01_03020 c16813336f140eab20259aa5a8703388 253 SUPERFAMILY SSF102114 32 208 9.29E-11 T 23-10-2018 A3L01_09800 ece2b94745f2c040354ee7e67aed2f4a 301 Pfam PF02355 Protein export membrane protein 122 295 5.7E-30 T 23-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A3L01_09800 ece2b94745f2c040354ee7e67aed2f4a 301 Hamap MF_01464_A Protein-export membrane protein SecF [secF]. 28 300 25.626 T 23-10-2018 IPR024921 Protein-export membrane protein SecF, archaeal GO:0016021|GO:0065002 A3L01_09800 ece2b94745f2c040354ee7e67aed2f4a 301 Gene3D G3DSA:1.20.1640.10 114 299 5.3E-15 T 23-10-2018 A3L01_09800 ece2b94745f2c040354ee7e67aed2f4a 301 SUPERFAMILY SSF82866 124 288 1.7E-24 T 23-10-2018 A3L01_07955 f2b7cf971024582b26b8186143632c9c 65 Pfam PF01954 Protein of unknown function DUF104 1 59 4.0E-15 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 A3L01_07955 f2b7cf971024582b26b8186143632c9c 65 Gene3D G3DSA:4.10.1150.10 1 65 2.1E-13 T 23-10-2018 IPR024069 AF2212-like domain superfamily A3L01_07955 f2b7cf971024582b26b8186143632c9c 65 SUPERFAMILY SSF141694 1 63 1.62E-14 T 23-10-2018 A3L01_10055 384b05614b14fddc234651c609e2b392 136 SUPERFAMILY SSF53335 6 101 1.99E-6 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_10055 384b05614b14fddc234651c609e2b392 136 Hamap MF_00341 UPF0146 protein . 3 132 26.399 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 A3L01_10055 384b05614b14fddc234651c609e2b392 136 Gene3D G3DSA:3.40.50.150 1 136 2.5E-25 T 23-10-2018 A3L01_10055 384b05614b14fddc234651c609e2b392 136 ProDom PD021130 UPF0146 MJ0688 SIMILAR ARCHAEA UNCHARACTERIZED AF0739.1 MTH1000 PYRAB01940 PH0209 VNG2609C 19 112 3.0E-39 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 A3L01_10055 384b05614b14fddc234651c609e2b392 136 Pfam PF03686 Uncharacterised protein family (UPF0146) 4 131 4.2E-31 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 A3L01_09550 5944ec0211daf907137408303ea4fa09 305 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 192 291 1.3E-25 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 A3L01_09550 5944ec0211daf907137408303ea4fa09 305 SUPERFAMILY SSF52402 24 245 4.63E-51 T 23-10-2018 A3L01_09550 5944ec0211daf907137408303ea4fa09 305 Gene3D G3DSA:3.40.50.620 1 304 1.1E-90 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_09550 5944ec0211daf907137408303ea4fa09 305 Pfam PF01171 PP-loop family 50 220 2.0E-13 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A3L01_09550 5944ec0211daf907137408303ea4fa09 305 PIRSF PIRSF004976 1 302 1.2E-95 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 A3L01_09835 c5dd00400396489cbbf9d4c05051e2cc 366 Pfam PF01992 ATP synthase (C/AC39) subunit 39 360 2.8E-65 T 23-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L01_09835 c5dd00400396489cbbf9d4c05051e2cc 366 SUPERFAMILY SSF103486 35 361 2.62E-76 T 23-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L01_09835 c5dd00400396489cbbf9d4c05051e2cc 366 TIGRFAM TIGR02923 AhaC: ATP synthase A1, C subunit 32 361 1.6E-103 T 23-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 A3L01_09835 c5dd00400396489cbbf9d4c05051e2cc 366 Gene3D G3DSA:1.20.1690.10 220 323 7.3E-58 T 23-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L01_09835 c5dd00400396489cbbf9d4c05051e2cc 366 Gene3D G3DSA:1.20.1690.10 112 209 7.3E-58 T 23-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L01_09835 c5dd00400396489cbbf9d4c05051e2cc 366 Gene3D G3DSA:1.10.132.50 35 354 7.3E-58 T 23-10-2018 A3L01_09835 c5dd00400396489cbbf9d4c05051e2cc 366 Hamap MF_00314 V-type ATP synthase subunit C [atpC]. 31 363 24.901 T 23-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 A3L01_03180 5d777f82a516a85e08a8a76713ae4049 495 Pfam PF00361 Proton-conducting membrane transporter 130 416 1.4E-64 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_03180 5d777f82a516a85e08a8a76713ae4049 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 78 103 3.4E-11 T 23-10-2018 A3L01_03180 5d777f82a516a85e08a8a76713ae4049 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 151 172 3.4E-11 T 23-10-2018 A3L01_03180 5d777f82a516a85e08a8a76713ae4049 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 309 321 3.4E-11 T 23-10-2018 A3L01_03180 5d777f82a516a85e08a8a76713ae4049 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 3.4E-11 T 23-10-2018 A3L01_03180 5d777f82a516a85e08a8a76713ae4049 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 238 264 3.4E-11 T 23-10-2018 A3L01_03180 5d777f82a516a85e08a8a76713ae4049 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 413 432 3.4E-11 T 23-10-2018 A3L01_01075 d1fcc18b3c660695cbd991f6908d8b3e 88 Hamap MF_00754 Ribonuclease P protein component 1 [rnp1]. 8 83 18.808 T 23-10-2018 IPR023538 Ribonuclease P protein component 1 GO:0001682|GO:0004526 A3L01_01075 d1fcc18b3c660695cbd991f6908d8b3e 88 Gene3D G3DSA:2.30.30.210 1 88 3.0E-31 T 23-10-2018 IPR036980 Ribonuclease P/MRP, subunit p29 superfamily GO:0003723|GO:0004540|GO:0008033|GO:0030677 Reactome: R-HSA-6784531 A3L01_01075 d1fcc18b3c660695cbd991f6908d8b3e 88 Pfam PF01868 Domain of unknown function UPF0086 5 84 1.3E-18 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 A3L01_01075 d1fcc18b3c660695cbd991f6908d8b3e 88 SUPERFAMILY SSF101744 2 87 2.09E-23 T 23-10-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 A3L01_01075 d1fcc18b3c660695cbd991f6908d8b3e 88 SMART SM00538 1 88 1.9E-28 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 A3L01_08335 caa251362f2c9171974dceda0e6dec9c 652 SUPERFAMILY SSF52540 1 408 1.57E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_08335 caa251362f2c9171974dceda0e6dec9c 652 Pfam PF13175 AAA ATPase domain 1 406 5.6E-57 T 23-10-2018 A3L01_07165 6d6d723eb4ef486eec34812bb7aa8088 335 SUPERFAMILY SSF46785 267 331 1.01E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_07165 6d6d723eb4ef486eec34812bb7aa8088 335 Pfam PF04122 Putative cell wall binding repeat 2 115 175 1.2E-6 T 23-10-2018 IPR007253 Putative cell wall binding repeat 2 A3L01_07165 6d6d723eb4ef486eec34812bb7aa8088 335 Gene3D G3DSA:1.10.10.10 267 331 2.5E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_06595 febec53bdef6ddcc31f4970d5c6db8a2 184 Gene3D G3DSA:1.10.3210.10 2 183 4.9E-62 T 23-10-2018 A3L01_06595 febec53bdef6ddcc31f4970d5c6db8a2 184 SUPERFAMILY SSF109604 3 177 4.19E-42 T 23-10-2018 A3L01_06595 febec53bdef6ddcc31f4970d5c6db8a2 184 SMART SM00471 28 146 3.4E-12 T 23-10-2018 IPR003607 HD/PDEase domain A3L01_06595 febec53bdef6ddcc31f4970d5c6db8a2 184 Pfam PF13023 HD domain 11 153 2.9E-32 T 23-10-2018 IPR006674 HD domain A3L01_07025 333f1a77940b3d1245312f2f030252a0 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 333 4.0E-44 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_07025 333f1a77940b3d1245312f2f030252a0 333 SUPERFAMILY SSF161098 96 320 1.55E-18 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_03135 791493196e2af411a17ae247c2688b8f 433 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 23 430 4.0E-96 T 23-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A3L01_03135 791493196e2af411a17ae247c2688b8f 433 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 348 368 - T 23-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A3L01_03135 791493196e2af411a17ae247c2688b8f 433 Pfam PF00860 Permease family 24 401 1.9E-93 T 23-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A3L01_07470 18d3d7c417748988b0a57279ba400e0b 478 Gene3D G3DSA:3.10.20.440 5 99 7.6E-34 T 23-10-2018 A3L01_07470 18d3d7c417748988b0a57279ba400e0b 478 Gene3D G3DSA:3.50.50.60 118 442 2.8E-59 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_07470 18d3d7c417748988b0a57279ba400e0b 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 391 413 2.1E-26 T 23-10-2018 A3L01_07470 18d3d7c417748988b0a57279ba400e0b 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 225 243 2.1E-26 T 23-10-2018 A3L01_07470 18d3d7c417748988b0a57279ba400e0b 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 287 2.1E-26 T 23-10-2018 A3L01_07470 18d3d7c417748988b0a57279ba400e0b 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 119 138 2.1E-26 T 23-10-2018 A3L01_07470 18d3d7c417748988b0a57279ba400e0b 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 359 375 2.1E-26 T 23-10-2018 A3L01_07470 18d3d7c417748988b0a57279ba400e0b 478 SUPERFAMILY SSF51905 107 433 3.67E-42 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_07470 18d3d7c417748988b0a57279ba400e0b 478 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 60 68 - T 23-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A3L01_07470 18d3d7c417748988b0a57279ba400e0b 478 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 118 425 6.1E-39 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L01_07470 18d3d7c417748988b0a57279ba400e0b 478 SUPERFAMILY SSF54292 17 99 1.19E-21 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A3L01_07470 18d3d7c417748988b0a57279ba400e0b 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 360 374 4.7E-22 T 23-10-2018 A3L01_07470 18d3d7c417748988b0a57279ba400e0b 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 413 4.7E-22 T 23-10-2018 A3L01_07470 18d3d7c417748988b0a57279ba400e0b 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 228 237 4.7E-22 T 23-10-2018 A3L01_07470 18d3d7c417748988b0a57279ba400e0b 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 118 140 4.7E-22 T 23-10-2018 A3L01_07470 18d3d7c417748988b0a57279ba400e0b 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 294 4.7E-22 T 23-10-2018 A3L01_07470 18d3d7c417748988b0a57279ba400e0b 478 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 15 95 3.6E-28 T 23-10-2018 A3L01_07470 18d3d7c417748988b0a57279ba400e0b 478 Gene3D G3DSA:3.50.50.60 237 367 2.8E-59 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L01_09715 81858ee95577edecafda6dd0a489226c 344 Pfam PF17231 Family of unknown function (DUF5305) 119 335 2.5E-33 T 23-10-2018 IPR035185 Protein of unknown function DUF5305 A3L01_04480 80d8e0040251cc4062227c8b11b73062 435 PIRSF PIRSF009445 1 434 4.0E-193 T 23-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 A3L01_04480 80d8e0040251cc4062227c8b11b73062 435 Hamap MF_01908 Cyclic 2,3-diphosphoglycerate synthetase [cpgS]. 4 435 49.147 T 23-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 A3L01_04480 80d8e0040251cc4062227c8b11b73062 435 Gene3D G3DSA:3.40.50.300 181 322 2.2E-7 T 23-10-2018 A3L01_04705 9df7adb3d9f3bfb3d940d246052d729e 148 Pfam PF10015 Uncharacterized protein conserved in archaea (DUF2258) 3 73 1.5E-22 T 23-10-2018 IPR017140 Uncharacterised conserved protein UCP037214 A3L01_01885 b964f6c605285e8f5d5d98b0ed71e8f6 433 Pfam PF07282 Putative transposase DNA-binding domain 319 393 5.0E-11 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L01_01885 b964f6c605285e8f5d5d98b0ed71e8f6 433 Pfam PF01385 Probable transposase 185 300 1.9E-26 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 A3L01_01885 b964f6c605285e8f5d5d98b0ed71e8f6 433 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 265 346 3.7E-25 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L01_02965 a691370a54b7a9ee214b4246dce6aea3 108 Gene3D G3DSA:1.10.10.1220 1 88 5.3E-45 T 23-10-2018 A3L01_02965 a691370a54b7a9ee214b4246dce6aea3 108 SUPERFAMILY SSF52467 2 73 5.64E-5 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A3L01_08990 90668365be86681a00ad2627b2921b46 262 Pfam PF05763 Protein of unknown function (DUF835) 127 248 4.9E-30 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L01_05525 0913cd80c7dc567db581d74fc9ff9e38 231 Gene3D G3DSA:3.40.50.300 4 231 9.5E-46 T 23-10-2018 A3L01_05525 0913cd80c7dc567db581d74fc9ff9e38 231 Pfam PF06745 KaiC 14 219 3.8E-17 T 23-10-2018 IPR014774 KaiC-like domain A3L01_05525 0913cd80c7dc567db581d74fc9ff9e38 231 SUPERFAMILY SSF52540 3 220 9.5E-27 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_05650 c5ec1956c98a0e41a5d78425c205fa9e 263 SMART SM00382 26 210 1.3E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L01_05650 c5ec1956c98a0e41a5d78425c205fa9e 263 SUPERFAMILY SSF52540 2 220 1.61E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_05650 c5ec1956c98a0e41a5d78425c205fa9e 263 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L01_05650 c5ec1956c98a0e41a5d78425c205fa9e 263 Pfam PF00005 ABC transporter 27 162 1.3E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L01_05650 c5ec1956c98a0e41a5d78425c205fa9e 263 Gene3D G3DSA:3.40.50.300 1 249 6.0E-70 T 23-10-2018 A3L01_01795 08197646c033ccd56876911f937502ed 393 SUPERFAMILY SSF53448 50 288 1.29E-7 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_01795 08197646c033ccd56876911f937502ed 393 TIGRFAM TIGR02460 osmo_MPGsynth: mannosyl-3-phosphoglycerate synthase 2 381 5.2E-178 T 23-10-2018 IPR012812 Mannosyl-3-phosphoglycerate synthase GO:0005737|GO:0050504|GO:0051479 KEGG: 00051+2.4.1.217|MetaCyc: PWY-5656 A3L01_01795 08197646c033ccd56876911f937502ed 393 Pfam PF09488 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) 7 380 8.4E-155 T 23-10-2018 IPR012812 Mannosyl-3-phosphoglycerate synthase GO:0005737|GO:0050504|GO:0051479 KEGG: 00051+2.4.1.217|MetaCyc: PWY-5656 A3L01_01795 08197646c033ccd56876911f937502ed 393 Gene3D G3DSA:3.90.550.10 1 393 2.2E-156 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_08680 0c4fb097ca0d266fc477d0deaf8777e5 123 Pfam PF03334 Na+/H+ antiporter subunit 11 100 2.8E-23 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L01_08680 0c4fb097ca0d266fc477d0deaf8777e5 123 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 114 1.5E-34 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L01_00745 aa1c91bf536f665d68f04a5d564552d8 227 Gene3D G3DSA:3.30.420.440 1 227 9.4E-104 T 23-10-2018 A3L01_00745 aa1c91bf536f665d68f04a5d564552d8 227 Pfam PF13680 Protein of unknown function (DUF4152) 1 224 3.5E-127 T 23-10-2018 IPR025206 Protein of unknown function DUF4152 A3L01_08770 d06ed330405e856eef8f385043287e2f 117 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7 113 3.6E-28 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A3L01_02535 d6121d2c09e06b32a16dcc8dfa312f1a 276 Gene3D G3DSA:1.25.40.10 81 218 1.5E-8 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_07065 b536d78f8b9ce31901d2aeaa792ad37d 364 Pfam PF01637 ATPase domain predominantly from Archaea 15 247 4.7E-16 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L01_07065 b536d78f8b9ce31901d2aeaa792ad37d 364 Gene3D G3DSA:1.10.8.60 207 284 2.5E-23 T 23-10-2018 A3L01_07065 b536d78f8b9ce31901d2aeaa792ad37d 364 SUPERFAMILY SSF52540 2 281 8.87E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_07065 b536d78f8b9ce31901d2aeaa792ad37d 364 SUPERFAMILY SSF46785 288 361 4.25E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_07065 b536d78f8b9ce31901d2aeaa792ad37d 364 Gene3D G3DSA:1.10.10.10 285 362 6.7E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_07065 b536d78f8b9ce31901d2aeaa792ad37d 364 Gene3D G3DSA:3.40.50.300 1 205 1.5E-43 T 23-10-2018 A3L01_02365 e217864c3bf591d990ccc4e1cf287f9a 241 Pfam PF00491 Arginase family 56 224 1.2E-17 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L01_02365 e217864c3bf591d990ccc4e1cf287f9a 241 SUPERFAMILY SSF52768 56 227 8.46E-25 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily A3L01_02365 e217864c3bf591d990ccc4e1cf287f9a 241 PIRSF PIRSF036979 33 229 9.7E-15 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L01_02365 e217864c3bf591d990ccc4e1cf287f9a 241 Gene3D G3DSA:3.40.800.10 39 241 2.3E-18 T 23-10-2018 A3L01_00510 72168a3a76146af813b8b9647a6118f8 125 SUPERFAMILY SSF50249 24 89 2.51E-6 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L01_02495 c419be6cbeecceabd56d0dce2d42abe3 271 Pfam PF02673 Bacitracin resistance protein BacA 11 254 8.7E-23 T 23-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A3L01_07585 33950bfdd1876585828e0855a8d7cd2f 261 Pfam PF02006 Phosphopantothenate/pantothenate synthetase 66 241 2.8E-76 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase A3L01_07585 33950bfdd1876585828e0855a8d7cd2f 261 PIRSF PIRSF004853 1 253 1.1E-114 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase A3L01_07585 33950bfdd1876585828e0855a8d7cd2f 261 Gene3D G3DSA:3.40.50.12640 1 261 5.5E-122 T 23-10-2018 IPR038138 Phosphopantoate/pantothenate synthetase superfamily A3L01_07585 33950bfdd1876585828e0855a8d7cd2f 261 ProDom PD016827 ARCHAEA ST0532 APE1937 VNG0250C MM2281 PAE3406 AF0927 UNCHARACTERIZED C3_0043 MJ0209 70 252 2.0E-92 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase A3L01_04495 0a4a98ba55a918aa58011b612ad9a83c 212 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 13 209 1.1E-29 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 A3L01_04495 0a4a98ba55a918aa58011b612ad9a83c 212 Gene3D G3DSA:3.90.320.10 4 210 7.7E-23 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal A3L01_04495 0a4a98ba55a918aa58011b612ad9a83c 212 Pfam PF12705 PD-(D/E)XK nuclease superfamily 61 207 1.3E-5 T 23-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type A3L01_10165 b7bc4fc6e80337049d61dc1c56ead90e 144 SUPERFAMILY SSF47240 2 143 1.31E-15 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L01_10165 b7bc4fc6e80337049d61dc1c56ead90e 144 Pfam PF02915 Rubrerythrin 30 139 4.1E-10 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L01_10165 b7bc4fc6e80337049d61dc1c56ead90e 144 Gene3D G3DSA:1.20.1260.10 1 144 3.1E-14 T 23-10-2018 IPR012347 Ferritin-like A3L01_06100 e010ab5ab892a8ef2371cdd0cb17213a 141 Pfam PF05763 Protein of unknown function (DUF835) 30 138 2.0E-21 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L01_01520 04fc12303c9fbdb1430ea3de1dfeba46 105 ProSitePatterns PS00638 P-II protein C-terminal region signature. 75 88 - T 23-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 A3L01_01520 04fc12303c9fbdb1430ea3de1dfeba46 105 Gene3D G3DSA:3.30.70.120 1 105 9.2E-39 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A3L01_01520 04fc12303c9fbdb1430ea3de1dfeba46 105 SMART SM00938 4 97 1.1E-41 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A3L01_01520 04fc12303c9fbdb1430ea3de1dfeba46 105 PRINTS PR00340 P-II protein signature 75 95 5.3E-24 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A3L01_01520 04fc12303c9fbdb1430ea3de1dfeba46 105 PRINTS PR00340 P-II protein signature 44 67 5.3E-24 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A3L01_01520 04fc12303c9fbdb1430ea3de1dfeba46 105 PRINTS PR00340 P-II protein signature 2 17 5.3E-24 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A3L01_01520 04fc12303c9fbdb1430ea3de1dfeba46 105 SUPERFAMILY SSF54913 1 104 2.67E-35 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A3L01_01520 04fc12303c9fbdb1430ea3de1dfeba46 105 Pfam PF00543 Nitrogen regulatory protein P-II 4 97 9.6E-30 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A3L01_06515 44b898d51f0f84e95168293a774603ed 189 SMART SM01022 4 104 1.6E-24 T 23-10-2018 IPR007374 ASCH domain A3L01_06515 44b898d51f0f84e95168293a774603ed 189 SUPERFAMILY SSF88697 2 103 4.72E-23 T 23-10-2018 IPR015947 PUA-like superfamily A3L01_06515 44b898d51f0f84e95168293a774603ed 189 Pfam PF04266 ASCH domain 4 104 3.6E-16 T 23-10-2018 IPR007374 ASCH domain A3L01_04860 ed55a13e6b95a42cf00999d0b9452543 398 Pfam PF03222 Tryptophan/tyrosine permease family 69 395 7.7E-29 T 23-10-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 A3L01_09880 3d499a8b31b165fde94d658ffe9d812f 355 SUPERFAMILY SSF161098 114 335 3.92E-9 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_09880 3d499a8b31b165fde94d658ffe9d812f 355 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 136 349 2.6E-16 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L01_09880 3d499a8b31b165fde94d658ffe9d812f 355 Gene3D G3DSA:1.10.3720.10 108 352 1.2E-6 T 23-10-2018 IPR035906 MetI-like superfamily A3L01_04160 c461e8300de089b53d7e7bd984bd4219 248 Pfam PF13649 Methyltransferase domain 45 139 1.5E-25 T 23-10-2018 A3L01_04160 c461e8300de089b53d7e7bd984bd4219 248 Gene3D G3DSA:3.40.50.150 1 149 6.8E-50 T 23-10-2018 A3L01_04160 c461e8300de089b53d7e7bd984bd4219 248 SUPERFAMILY SSF53335 3 246 1.47E-48 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_04160 c461e8300de089b53d7e7bd984bd4219 248 Gene3D G3DSA:2.20.25.110 150 209 3.4E-29 T 23-10-2018 A3L01_06570 53b090bf7742d9a163f618f0d16d679e 218 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 16 129 3.7E-35 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain A3L01_06570 53b090bf7742d9a163f618f0d16d679e 218 SUPERFAMILY SSF118196 4 134 2.09E-39 T 23-10-2018 IPR036413 YaeB-like superfamily A3L01_06570 53b090bf7742d9a163f618f0d16d679e 218 Gene3D G3DSA:2.40.30.70 4 143 8.6E-31 T 23-10-2018 IPR036414 YaeB, N-terminal domain superfamily A3L01_06570 53b090bf7742d9a163f618f0d16d679e 218 ProSitePatterns PS01318 TsaA-like domain signature. 73 84 - T 23-10-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site A3L01_06570 53b090bf7742d9a163f618f0d16d679e 218 Pfam PF01980 Uncharacterised protein family UPF0066 16 125 1.3E-29 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain A3L01_08740 9007c083449ac816c2c94385c673291c 167 Pfam PF01899 Na+/H+ ion antiporter subunit 7 165 6.7E-39 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L01_08740 9007c083449ac816c2c94385c673291c 167 PIRSF PIRSF019239 1 167 6.4E-37 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L01_04825 2560440514fae9bf5b137809a9004992 426 Pfam PF07690 Major Facilitator Superfamily 19 383 7.3E-43 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L01_04825 2560440514fae9bf5b137809a9004992 426 SUPERFAMILY SSF103473 5 425 1.57E-77 T 23-10-2018 IPR036259 MFS transporter superfamily A3L01_04825 2560440514fae9bf5b137809a9004992 426 ProSitePatterns PS00217 Sugar transport proteins signature 2. 114 139 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A3L01_04825 2560440514fae9bf5b137809a9004992 426 Gene3D G3DSA:1.10.286.90 194 230 1.0E-6 T 23-10-2018 A3L01_08210 ad72a5b58349bd0c58a5ea091dab802f 331 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 57 218 1.8E-25 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L01_08210 ad72a5b58349bd0c58a5ea091dab802f 331 SUPERFAMILY SSF52518 12 318 4.91E-76 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L01_08210 ad72a5b58349bd0c58a5ea091dab802f 331 Gene3D G3DSA:3.40.50.970 14 96 2.6E-10 T 23-10-2018 A3L01_08210 ad72a5b58349bd0c58a5ea091dab802f 331 Gene3D G3DSA:3.40.50.970 97 321 2.2E-67 T 23-10-2018 A3L01_07895 2ffdb4a73bf79676dbd4ebdbc2876515 145 Gene3D G3DSA:3.90.960.10 1 145 1.3E-34 T 23-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 A3L01_07895 2ffdb4a73bf79676dbd4ebdbc2876515 145 SUPERFAMILY SSF55826 20 144 4.97E-29 T 23-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 A3L01_07895 2ffdb4a73bf79676dbd4ebdbc2876515 145 Pfam PF04073 Aminoacyl-tRNA editing domain 21 132 1.5E-26 T 23-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A3L01_09940 1237d41cec92562f07391a16b4c7227c 253 Gene3D G3DSA:3.40.50.620 7 253 1.2E-90 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_09940 1237d41cec92562f07391a16b4c7227c 253 Pfam PF02540 NAD synthase 10 248 6.4E-84 T 23-10-2018 IPR022310 NAD/GMP synthase A3L01_09940 1237d41cec92562f07391a16b4c7227c 253 TIGRFAM TIGR00552 nadE: NAD+ synthetase 9 248 1.1E-81 T 23-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 A3L01_09940 1237d41cec92562f07391a16b4c7227c 253 SUPERFAMILY SSF52402 3 249 3.09E-77 T 23-10-2018 A3L01_09940 1237d41cec92562f07391a16b4c7227c 253 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 5 251 50.581 T 23-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 A3L01_05295 4c3083e97e44bfccaed334ed55e1cf6c 188 Pfam PF06197 Protein of unknown function (DUF998) 13 181 2.4E-23 T 23-10-2018 IPR009339 Protein of unknown function DUF998 A3L01_00615 0862bd0284eb87a329d09ead6b6d4d55 329 SUPERFAMILY SSF51713 58 234 1.44E-11 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L01_06225 f86d0b218022862bafde6a7de69870a4 108 Gene3D G3DSA:2.30.30.240 3 81 1.4E-5 T 23-10-2018 A3L01_06225 f86d0b218022862bafde6a7de69870a4 108 Pfam PF05239 PRC-barrel domain 2 82 1.3E-13 T 23-10-2018 IPR027275 PRC-barrel domain A3L01_06225 f86d0b218022862bafde6a7de69870a4 108 SUPERFAMILY SSF50346 4 79 1.57E-12 T 23-10-2018 IPR011033 PRC-barrel-like superfamily A3L01_04985 c0227e4dec46b5838d2a59f03c923dab 115 Pfam PF01880 Desulfoferrodoxin 9 111 1.7E-32 T 23-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 A3L01_04985 c0227e4dec46b5838d2a59f03c923dab 115 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 8 114 9.9E-34 T 23-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 A3L01_04985 c0227e4dec46b5838d2a59f03c923dab 115 Gene3D G3DSA:2.60.40.730 1 115 2.6E-51 T 23-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 A3L01_04985 c0227e4dec46b5838d2a59f03c923dab 115 SUPERFAMILY SSF49367 5 114 2.62E-40 T 23-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 A3L01_09515 22cd3277aeba955b39cef0fd4def37f0 391 Gene3D G3DSA:1.20.1530.20 1 391 9.9E-76 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L01_09515 22cd3277aeba955b39cef0fd4def37f0 391 Pfam PF00999 Sodium/hydrogen exchanger family 9 382 1.6E-55 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L01_00910 26985d3ba4d51b86d6c22a7f4dc4a839 233 Gene3D G3DSA:3.40.50.11570 11 218 2.7E-52 T 23-10-2018 A3L01_00910 26985d3ba4d51b86d6c22a7f4dc4a839 233 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 17 215 1.8E-57 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L01_05955 44b4d5dd45bdf00b1821471696b889d9 269 Pfam PF01889 Membrane protein of unknown function DUF63 4 268 5.0E-84 T 23-10-2018 IPR002749 Protein of unknown function DUF63 A3L01_04270 a3e95ab59ece15b157878e3024a61aae 336 Pfam PF01916 Deoxyhypusine synthase 34 331 2.5E-113 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 A3L01_04270 a3e95ab59ece15b157878e3024a61aae 336 SUPERFAMILY SSF52467 5 334 8.83E-116 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A3L01_04270 a3e95ab59ece15b157878e3024a61aae 336 Hamap MF_00153 Probable deoxyhypusine synthase [dys]. 31 334 42.381 T 23-10-2018 IPR022899 Deoxyhypusine synthase, putative, archaeal GO:0034038 A3L01_04270 a3e95ab59ece15b157878e3024a61aae 336 TIGRFAM TIGR00321 dhys: deoxyhypusine synthase 20 335 4.1E-121 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 A3L01_04270 a3e95ab59ece15b157878e3024a61aae 336 Gene3D G3DSA:3.40.910.10 2 336 1.7E-146 T 23-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 A3L01_09340 daea4c9aa2e1b890f453f8c5791cdb81 102 SMART SM00418 6 93 0.0025 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L01_09340 daea4c9aa2e1b890f453f8c5791cdb81 102 Pfam PF13601 Winged helix DNA-binding domain 17 94 5.9E-21 T 23-10-2018 IPR027395 Winged helix DNA-binding domain A3L01_09340 daea4c9aa2e1b890f453f8c5791cdb81 102 Gene3D G3DSA:1.10.10.10 1 98 3.5E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_09340 daea4c9aa2e1b890f453f8c5791cdb81 102 SUPERFAMILY SSF46785 10 95 7.29E-19 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_03250 4a11d0825dc89982dfef6240fdf63387 92 SUPERFAMILY SSF82649 4 86 4.45E-10 T 23-10-2018 A3L01_03250 4a11d0825dc89982dfef6240fdf63387 92 Gene3D G3DSA:3.30.390.50 1 88 1.6E-25 T 23-10-2018 A3L01_03250 4a11d0825dc89982dfef6240fdf63387 92 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 7 58 3.3E-7 T 23-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 A3L01_00250 ee025b272f2963c7ea08a2589f216fa5 178 Gene3D G3DSA:3.90.80.10 1 178 2.2E-75 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L01_00250 ee025b272f2963c7ea08a2589f216fa5 178 SUPERFAMILY SSF50324 2 172 1.14E-67 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L01_00250 ee025b272f2963c7ea08a2589f216fa5 178 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 15 171 36.682 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L01_00250 ee025b272f2963c7ea08a2589f216fa5 178 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L01_00250 ee025b272f2963c7ea08a2589f216fa5 178 Pfam PF00719 Inorganic pyrophosphatase 20 171 4.6E-58 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L01_00590 726eb5cd93411133952315b615ac91a4 100 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 2 96 1.4E-28 T 23-10-2018 IPR002767 Thiamine-binding protein A3L01_00590 726eb5cd93411133952315b615ac91a4 100 SUPERFAMILY SSF89957 2 95 6.41E-30 T 23-10-2018 IPR029756 MTH1187/YkoF-like A3L01_00590 726eb5cd93411133952315b615ac91a4 100 Pfam PF01910 Thiamine-binding protein 4 93 1.1E-31 T 23-10-2018 IPR002767 Thiamine-binding protein A3L01_00590 726eb5cd93411133952315b615ac91a4 100 Gene3D G3DSA:3.30.70.930 1 97 7.7E-34 T 23-10-2018 IPR029756 MTH1187/YkoF-like A3L01_07560 aa63bd6545bbbc95fa2d35d89e3befed 231 Gene3D G3DSA:3.40.50.300 1 231 2.1E-55 T 23-10-2018 A3L01_09815 3a434bc648f21e7abf83aa0dd56dc790 103 TIGRFAM TIGR02926 AhaH: ATP synthase archaeal, H subunit 5 89 2.1E-18 T 23-10-2018 IPR014275 ATPase, A1A0, subunit H A3L01_09815 3a434bc648f21e7abf83aa0dd56dc790 103 SUPERFAMILY SSF81573 36 88 7.19E-7 T 23-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily A3L01_09815 3a434bc648f21e7abf83aa0dd56dc790 103 Gene3D G3DSA:1.20.5.620 33 91 2.3E-6 T 23-10-2018 A3L01_03280 c75d350fe167b32ec690978d3f2a7ca0 187 SUPERFAMILY SSF48371 32 156 4.87E-12 T 23-10-2018 IPR016024 Armadillo-type fold A3L01_03280 c75d350fe167b32ec690978d3f2a7ca0 187 Gene3D G3DSA:1.25.10.10 13 159 1.0E-10 T 23-10-2018 IPR011989 Armadillo-like helical A3L01_07310 88abb52a11285c682a2e3abc68ec57f4 93 PIRSF PIRSF004604 1 93 1.1E-21 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L01_07310 88abb52a11285c682a2e3abc68ec57f4 93 Gene3D G3DSA:3.30.2320.10 1 93 3.1E-27 T 23-10-2018 A3L01_07310 88abb52a11285c682a2e3abc68ec57f4 93 Pfam PF08967 Domain of unknown function (DUF1884) 2 92 8.9E-40 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L01_07310 88abb52a11285c682a2e3abc68ec57f4 93 SUPERFAMILY SSF111057 1 92 4.05E-32 T 23-10-2018 IPR036216 Hypothetical protein UCP004604 superfamily A3L01_07310 88abb52a11285c682a2e3abc68ec57f4 93 ProDom PD029791 ORF 3'REGION GAP PF1875 PF0899 PH1831 B PHS036 2 92 3.0E-25 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L01_03210 61255170427c302b5aa6838075290b1c 168 Pfam PF01899 Na+/H+ ion antiporter subunit 15 164 1.9E-48 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L01_03210 61255170427c302b5aa6838075290b1c 168 PIRSF PIRSF019239 4 168 5.5E-55 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L01_08075 5081de0b58b44302c383600258dfcaa1 642 Gene3D G3DSA:3.30.230.10 32 226 2.1E-28 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L01_08075 5081de0b58b44302c383600258dfcaa1 642 SUPERFAMILY SSF54211 49 230 5.31E-25 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L01_08075 5081de0b58b44302c383600258dfcaa1 642 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 69 178 1.1E-12 T 23-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A3L01_03705 ccc6a683b80961e0c7d1d0a018b6ddbf 350 Pfam PF02653 Branched-chain amino acid transport system / permease component 60 331 5.3E-37 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A3L01_04215 bcb4b16fc98c537a95526a0f5b8d2704 196 Pfam PF01955 Adenosylcobinamide amidohydrolase 10 182 8.9E-45 T 23-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ A3L01_06105 bd108dd22d01089cd4d6d5642ce84926 133 Gene3D G3DSA:3.10.180.10 1 132 6.6E-44 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A3L01_06105 bd108dd22d01089cd4d6d5642ce84926 133 SUPERFAMILY SSF54593 1 132 4.23E-35 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A3L01_06105 bd108dd22d01089cd4d6d5642ce84926 133 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 130 3.4E-53 T 23-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 A3L01_06105 bd108dd22d01089cd4d6d5642ce84926 133 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 115 1.2E-25 T 23-10-2018 A3L01_05635 73e831be06516c4d0f3e24401b01e5c1 194 Pfam PF12804 MobA-like NTP transferase domain 18 150 1.0E-6 T 23-10-2018 IPR025877 MobA-like NTP transferase A3L01_05635 73e831be06516c4d0f3e24401b01e5c1 194 SUPERFAMILY SSF53448 18 135 4.13E-9 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_05635 73e831be06516c4d0f3e24401b01e5c1 194 Gene3D G3DSA:3.90.550.10 16 194 7.7E-12 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L01_06740 855c4a35f4de40fbffbf09472a607068 414 Pfam PF00534 Glycosyl transferases group 1 223 388 1.8E-25 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L01_06740 855c4a35f4de40fbffbf09472a607068 414 SUPERFAMILY SSF53756 39 407 1.37E-53 T 23-10-2018 A3L01_06740 855c4a35f4de40fbffbf09472a607068 414 Gene3D G3DSA:3.40.50.2000 199 395 9.9E-162 T 23-10-2018 A3L01_06740 855c4a35f4de40fbffbf09472a607068 414 Gene3D G3DSA:3.40.50.2000 12 198 9.9E-162 T 23-10-2018 A3L01_08260 bf69bab716379b7d2a20510a5858aff0 244 PIRSF PIRSF019322 2 244 1.3E-87 T 23-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 A3L01_08260 bf69bab716379b7d2a20510a5858aff0 244 Pfam PF09883 Uncharacterized protein conserved in archaea (DUF2110) 6 236 3.9E-72 T 23-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 A3L01_04255 6a26dcb9632597f8c014047e607ab2cf 318 Hamap MF_00584 Putative HTH-type transcriptional regulatory protein . 2 300 28.469 T 23-10-2018 IPR020886 Transcription regulator HTH, Cro/C1-type DNA-binding GO:0003700|GO:0006355 A3L01_04255 6a26dcb9632597f8c014047e607ab2cf 318 SMART SM00530 130 185 8.0E-13 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L01_04255 6a26dcb9632597f8c014047e607ab2cf 318 Pfam PF01381 Helix-turn-helix 131 184 1.8E-13 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L01_04255 6a26dcb9632597f8c014047e607ab2cf 318 SUPERFAMILY SSF47413 127 186 9.38E-13 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L01_04255 6a26dcb9632597f8c014047e607ab2cf 318 Gene3D G3DSA:1.10.260.40 130 187 2.6E-12 T 23-10-2018 A3L01_02080 99a03451bab17db562ea333e5b4f4508 409 Pfam PF12698 ABC-2 family transporter protein 24 399 3.7E-31 T 23-10-2018 A3L01_09705 8714c2013a2000b34f92d6cf77622d5e 200 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 9 38 1.9E-4 T 23-10-2018 IPR023833 Signal peptide, camelysin A3L01_00730 e8714774888e13b1bc28b5bdbcf10143 348 Pfam PF01594 AI-2E family transporter 11 322 1.7E-36 T 23-10-2018 IPR002549 Transmembrane protein TqsA-like A3L01_06435 3658c25578e14fcb8e37ba4f44711324 226 Gene3D G3DSA:3.60.110.10 1 225 7.9E-35 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A3L01_06435 3658c25578e14fcb8e37ba4f44711324 226 Pfam PF00795 Carbon-nitrogen hydrolase 3 208 1.2E-17 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A3L01_06435 3658c25578e14fcb8e37ba4f44711324 226 SUPERFAMILY SSF56317 1 213 1.57E-38 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A3L01_06720 625b4810553bb2d692724075f8ac4171 395 Gene3D G3DSA:3.20.20.80 3 365 2.2E-36 T 23-10-2018 A3L01_06720 625b4810553bb2d692724075f8ac4171 395 SUPERFAMILY SSF51445 3 354 1.97E-49 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L01_06720 625b4810553bb2d692724075f8ac4171 395 Pfam PF02449 Beta-galactosidase 24 185 2.2E-9 T 23-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A3L01_00380 397ce3ff77ee3f5f213e24052075e6b2 234 Pfam PF10086 Putative membrane peptidase family (DUF2324) 26 127 7.7E-6 T 23-10-2018 IPR011397 Uncharacterised conserved protein UCP033101 A3L01_00380 397ce3ff77ee3f5f213e24052075e6b2 234 Pfam PF10086 Putative membrane peptidase family (DUF2324) 136 205 4.5E-6 T 23-10-2018 IPR011397 Uncharacterised conserved protein UCP033101 A3L01_09560 f9d617b1c73f542d01aad3fe9df23dc2 202 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 15 184 2.6E-25 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L01_09560 f9d617b1c73f542d01aad3fe9df23dc2 202 Gene3D G3DSA:3.40.50.11570 4 198 2.4E-33 T 23-10-2018 A3L01_05900 c73d6ce9cd2bc82e48cdbb2a949dbb6a 203 Gene3D G3DSA:2.30.110.10 97 196 4.6E-5 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A3L01_07790 05af4b3b997796cf57a35f5c2c3b737d 103 SUPERFAMILY SSF81301 6 100 1.66E-25 T 23-10-2018 A3L01_07790 05af4b3b997796cf57a35f5c2c3b737d 103 Pfam PF01909 Nucleotidyltransferase domain 20 94 8.6E-17 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L01_07790 05af4b3b997796cf57a35f5c2c3b737d 103 Gene3D G3DSA:3.30.460.10 3 100 3.1E-26 T 23-10-2018 A3L01_02390 c41a25aea008c0a3acfc86c97153b43c 269 Pfam PF14336 Domain of unknown function (DUF4392) 3 260 2.0E-61 T 23-10-2018 IPR025504 Domain of unknown function DUF4392 KEGG: 00471+4.2.1.48 A3L01_02390 c41a25aea008c0a3acfc86c97153b43c 269 Gene3D G3DSA:3.90.1640.20 1 269 1.7E-97 T 23-10-2018 A3L01_07690 a37318139e416641aa9a7258f7b72fd0 194 SUPERFAMILY SSF53323 2 192 8.37E-27 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L01_07690 a37318139e416641aa9a7258f7b72fd0 194 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 190 1.5E-34 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L01_07690 a37318139e416641aa9a7258f7b72fd0 194 Gene3D G3DSA:3.40.920.10 1 194 2.0E-34 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L01_00525 00baced51199b12166c1fe2aa1946345 308 Pfam PF05763 Protein of unknown function (DUF835) 181 304 3.0E-29 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L01_06635 14001022e35b3b11060ced7361ec4f64 99 SUPERFAMILY SSF88723 12 84 7.29E-8 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L01_06635 14001022e35b3b11060ced7361ec4f64 99 Pfam PF10130 PIN domain 2 79 4.1E-15 T 23-10-2018 IPR002716 PIN domain A3L01_05010 198d0ad99ce544f6dce3ca7aace6f101 393 Pfam PF05763 Protein of unknown function (DUF835) 271 391 1.1E-23 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L01_00725 c49e7d3a01b6e38b9884e933f66604c2 181 SUPERFAMILY SSF52499 4 178 8.9E-56 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A3L01_00725 c49e7d3a01b6e38b9884e933f66604c2 181 Pfam PF00857 Isochorismatase family 5 178 3.0E-45 T 23-10-2018 IPR000868 Isochorismatase-like GO:0003824 A3L01_00725 c49e7d3a01b6e38b9884e933f66604c2 181 Gene3D G3DSA:3.40.50.850 1 179 2.5E-73 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A3L01_09270 530c439563bf7101e2e57bbe7f592fa0 164 PIRSF PIRSF019115 1 164 2.1E-67 T 23-10-2018 IPR019217 Protein of unknown function DUF2118 A3L01_09270 530c439563bf7101e2e57bbe7f592fa0 164 Gene3D G3DSA:2.40.50.100 97 163 1.5E-30 T 23-10-2018 A3L01_09270 530c439563bf7101e2e57bbe7f592fa0 164 Pfam PF09891 Uncharacterized protein conserved in archaea (DUF2118) 2 163 2.3E-51 T 23-10-2018 IPR019217 Protein of unknown function DUF2118 A3L01_06800 687d7a832770d534d0a9a2e3ec7a850a 164 Gene3D G3DSA:3.60.21.10 1 164 5.7E-41 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L01_06800 687d7a832770d534d0a9a2e3ec7a850a 164 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 2 158 1.2E-33 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A3L01_06800 687d7a832770d534d0a9a2e3ec7a850a 164 SUPERFAMILY SSF56300 2 163 4.09E-37 T 23-10-2018 A3L01_06800 687d7a832770d534d0a9a2e3ec7a850a 164 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 152 1.7E-25 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L01_03800 f6f2e3a0e3847f7863d2cd4c48001c6c 381 Pfam PF05559 Protein of unknown function (DUF763) 4 335 1.7E-121 T 23-10-2018 IPR008482 Protein of unknown function DUF763 A3L01_03400 033cb4d9cbf57ef04565b401384ca6e1 445 Pfam PF01458 Uncharacterized protein family (UPF0051) 194 417 6.9E-53 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A3L01_03400 033cb4d9cbf57ef04565b401384ca6e1 445 SUPERFAMILY SSF101960 18 441 3.01E-102 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily A3L01_02685 4a869182b93f4beaff828ba8674eadd0 247 Gene3D G3DSA:3.40.50.300 2 241 3.1E-46 T 23-10-2018 A3L01_02685 4a869182b93f4beaff828ba8674eadd0 247 SUPERFAMILY SSF52540 3 244 2.1E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_02685 4a869182b93f4beaff828ba8674eadd0 247 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 221 1.5E-18 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L01_04465 15b08c0f94e895c20396c21472bbc93f 135 Pfam PF00571 CBS domain 10 60 3.0E-10 T 23-10-2018 IPR000644 CBS domain A3L01_04465 15b08c0f94e895c20396c21472bbc93f 135 Pfam PF00571 CBS domain 71 123 3.5E-13 T 23-10-2018 IPR000644 CBS domain A3L01_04465 15b08c0f94e895c20396c21472bbc93f 135 SUPERFAMILY SSF54631 7 127 3.28E-31 T 23-10-2018 A3L01_04465 15b08c0f94e895c20396c21472bbc93f 135 SMART SM00116 78 125 1.1E-6 T 23-10-2018 IPR000644 CBS domain A3L01_04465 15b08c0f94e895c20396c21472bbc93f 135 SMART SM00116 14 61 1.0E-9 T 23-10-2018 IPR000644 CBS domain A3L01_04465 15b08c0f94e895c20396c21472bbc93f 135 Gene3D G3DSA:3.10.580.10 1 135 8.9E-44 T 23-10-2018 A3L01_02885 4c5b94f49b4f42592f3f32ced552898f 177 Pfam PF06195 Protein of unknown function (DUF996) 22 150 2.6E-25 T 23-10-2018 IPR010397 Protein of unknown function DUF996 A3L01_03455 7e09ed1787d025dbdcb18fe9c1b39a76 403 SUPERFAMILY SSF52317 51 315 4.12E-6 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_07205 e2f996e82146f8b0bef2391d6c81fe26 567 Pfam PF04458 Protein of unknown function (DUF505) 1 300 6.1E-74 T 23-10-2018 IPR007548 Protein of unknown function DUF505 A3L01_07205 e2f996e82146f8b0bef2391d6c81fe26 567 Pfam PF04458 Protein of unknown function (DUF505) 306 566 1.7E-77 T 23-10-2018 IPR007548 Protein of unknown function DUF505 A3L01_08975 08bb4824c64eb1ff37e603872bf73b73 341 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 11 321 3.4E-60 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L01_08975 08bb4824c64eb1ff37e603872bf73b73 341 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 11 337 9.9E-59 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L01_07520 25ea00721e818116038af3fddbe6d330 588 Gene3D G3DSA:1.50.10.20 335 484 1.3E-5 T 23-10-2018 A3L01_07520 25ea00721e818116038af3fddbe6d330 588 Gene3D G3DSA:1.50.10.20 22 124 6.7E-11 T 23-10-2018 A3L01_07520 25ea00721e818116038af3fddbe6d330 588 SUPERFAMILY SSF48239 52 233 1.35E-17 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L01_07520 25ea00721e818116038af3fddbe6d330 588 SUPERFAMILY SSF48239 402 483 7.85E-11 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L01_10290 b86d5d5d0457d79c30b7f4a6e1e290db 134 Gene3D G3DSA:3.30.460.10 5 97 4.2E-10 T 23-10-2018 A3L01_10290 b86d5d5d0457d79c30b7f4a6e1e290db 134 SUPERFAMILY SSF81301 12 96 5.35E-13 T 23-10-2018 A3L01_04770 2d0710e2aa4538a0cb35e8c2fd8b413f 123 TIGRFAM TIGR00494 crcB: protein CrcB 8 121 2.2E-27 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A3L01_04770 2d0710e2aa4538a0cb35e8c2fd8b413f 123 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 6 122 19.158 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A3L01_04770 2d0710e2aa4538a0cb35e8c2fd8b413f 123 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 8 117 9.9E-24 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A3L01_00645 a84f3538681887f888866c2a5b571b2b 235 Pfam PF13419 Haloacid dehalogenase-like hydrolase 96 199 8.4E-14 T 23-10-2018 A3L01_00645 a84f3538681887f888866c2a5b571b2b 235 Gene3D G3DSA:1.10.150.400 14 92 7.4E-64 T 23-10-2018 A3L01_00645 a84f3538681887f888866c2a5b571b2b 235 Gene3D G3DSA:3.40.50.1000 2 215 7.4E-64 T 23-10-2018 IPR023214 HAD superfamily A3L01_00645 a84f3538681887f888866c2a5b571b2b 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 5.4E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_00645 a84f3538681887f888866c2a5b571b2b 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 188 201 5.4E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_00645 a84f3538681887f888866c2a5b571b2b 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 158 5.4E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_00645 a84f3538681887f888866c2a5b571b2b 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 108 121 5.4E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L01_00645 a84f3538681887f888866c2a5b571b2b 235 SUPERFAMILY SSF56784 1 228 1.46E-33 T 23-10-2018 IPR036412 HAD-like superfamily A3L01_06525 c4dbb33aac55a55411ddca2827f85b99 405 Pfam PF06819 Archaeal Peptidase A24 C-terminal Domain 261 369 1.0E-27 T 23-10-2018 IPR009639 Peptidase A24A-predicted, C-terminal archaea A3L01_06525 c4dbb33aac55a55411ddca2827f85b99 405 Gene3D G3DSA:1.20.120.1220 56 173 7.0E-13 T 23-10-2018 A3L01_04385 b28215b03bb64dfa390933e819015b16 284 Pfam PF00892 EamA-like transporter family 6 139 5.0E-18 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L01_04385 b28215b03bb64dfa390933e819015b16 284 Pfam PF00892 EamA-like transporter family 149 271 4.9E-13 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L01_04385 b28215b03bb64dfa390933e819015b16 284 SUPERFAMILY SSF103481 182 274 4.18E-7 T 23-10-2018 A3L01_04385 b28215b03bb64dfa390933e819015b16 284 SUPERFAMILY SSF103481 41 143 8.63E-13 T 23-10-2018 A3L01_01770 e24260c0d2fe23b072500ae1920ba044 233 Pfam PF01963 TraB family 9 222 9.2E-16 T 23-10-2018 IPR002816 Pheromone shutdown, TraB A3L01_05100 cde4e9fd6e22d876f993a8fd34ee5d08 195 PIRSF PIRSF000495 1 195 1.1E-57 T 23-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A3L01_05100 cde4e9fd6e22d876f993a8fd34ee5d08 195 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 193 3.8E-61 T 23-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A3L01_05100 cde4e9fd6e22d876f993a8fd34ee5d08 195 SUPERFAMILY SSF52317 1 193 6.45E-48 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_05100 cde4e9fd6e22d876f993a8fd34ee5d08 195 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 195 34.142 T 23-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A3L01_05100 cde4e9fd6e22d876f993a8fd34ee5d08 195 Gene3D G3DSA:3.40.50.880 1 194 1.9E-63 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L01_05100 cde4e9fd6e22d876f993a8fd34ee5d08 195 Pfam PF00117 Glutamine amidotransferase class-I 35 189 1.1E-19 T 23-10-2018 IPR017926 Glutamine amidotransferase A3L01_09235 f9bd5d6b007b8bc8d2caa0408ace4bfe 113 TIGRFAM TIGR04076 TIGR04076: TIGR04076 family protein 1 96 7.3E-21 T 23-10-2018 IPR023811 Conserved hypothetical protein CHP04076 A3L01_05390 eb64719364335139ef9c688788603656 81 Pfam PF04457 Protein of unknown function (DUF504) 26 77 2.4E-14 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 A3L01_05390 eb64719364335139ef9c688788603656 81 Hamap MF_01245 UPF0248 protein . 10 79 18.779 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 A3L01_03295 12c9c46449571bd61d27140f4c86c054 416 Pfam PF02163 Peptidase family M50 302 347 2.9E-7 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L01_00660 68ad24213e479d5bd77663fc721afdc5 489 Pfam PF05124 S-layer like family, C-terminal region 384 488 8.8E-11 T 23-10-2018 IPR022651 S-layer protein, C-terminal A3L01_06950 39365db685bab8bfa7e072d01485f604 126 Pfam PF09946 Predicted membrane protein (DUF2178) 15 97 2.6E-13 T 23-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane A3L01_06620 ead1093d995157bff6e2f3f019e8deef 427 Gene3D G3DSA:1.25.40.10 260 410 2.6E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L01_00470 8f773791e8d2e8b9a10179391444e6cb 56 Pfam PF03911 Sec61beta family 11 51 1.6E-15 T 23-10-2018 IPR016482 Protein transport protein SecG/Sec61-beta/Sbh Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L01_00470 8f773791e8d2e8b9a10179391444e6cb 56 Hamap MF_00751 Preprotein translocase subunit SecG [secG]. 1 51 15.22 T 23-10-2018 IPR023531 Preprotein translocase subunit SecG A3L01_07040 5f62e8d7e03b4a4a5efdb1b35190f018 115 Pfam PF01922 SRP19 protein 5 83 1.0E-12 T 23-10-2018 IPR002778 Signal recognition particle, SRP19 subunit GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L01_07040 5f62e8d7e03b4a4a5efdb1b35190f018 115 SUPERFAMILY SSF69695 1 108 2.35E-22 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L01_07040 5f62e8d7e03b4a4a5efdb1b35190f018 115 Gene3D G3DSA:3.30.56.30 1 105 1.3E-30 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L01_09750 b7a2a8116f2ed72fb2f86fd159f1631f 185 Pfam PF03729 Short repeat of unknown function (DUF308) 79 141 4.9E-7 T 23-10-2018 IPR005325 Protein of unknown function DUF308, membrane A3L01_09750 b7a2a8116f2ed72fb2f86fd159f1631f 185 Pfam PF03729 Short repeat of unknown function (DUF308) 16 85 2.2E-10 T 23-10-2018 IPR005325 Protein of unknown function DUF308, membrane A3L01_06240 0a13ba63ca092ed7dfa3d7510d02f520 151 Pfam PF06146 Phosphate-starvation-inducible E 58 123 7.9E-12 T 23-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like A3L01_00775 b50466a15f55db7b69935deec4238a77 161 ProSitePatterns PS00892 HIT domain signature. 81 99 - T 23-10-2018 IPR019808 Histidine triad, conserved site A3L01_00775 b50466a15f55db7b69935deec4238a77 161 SUPERFAMILY SSF54197 2 119 8.97E-37 T 23-10-2018 IPR036265 HIT-like superfamily A3L01_00775 b50466a15f55db7b69935deec4238a77 161 Pfam PF01230 HIT domain 12 100 1.1E-21 T 23-10-2018 IPR001310 Histidine triad (HIT) protein A3L01_00775 b50466a15f55db7b69935deec4238a77 161 Gene3D G3DSA:3.30.428.10 1 142 4.7E-39 T 23-10-2018 IPR036265 HIT-like superfamily A3L01_08750 d1dc31331414bd6ed3bfb16345722121 117 Pfam PF03334 Na+/H+ antiporter subunit 9 98 3.7E-27 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L01_08750 d1dc31331414bd6ed3bfb16345722121 117 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 8 113 4.2E-32 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L01_08755 36b11463a45043d23635d93bff21aa96 87 Pfam PF13244 Domain of unknown function (DUF4040) 17 80 4.0E-20 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A3L01_08700 a60da086ff25924c1600e7e1b317b882 119 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 116 1.0E-25 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A3L01_08070 ee48998f272a8db248f431e460e9e3b3 183 SUPERFAMILY SSF52402 44 182 1.84E-10 T 23-10-2018 A3L01_08070 ee48998f272a8db248f431e460e9e3b3 183 Pfam PF00582 Universal stress protein family 66 182 2.2E-5 T 23-10-2018 IPR006016 UspA A3L01_08070 ee48998f272a8db248f431e460e9e3b3 183 Gene3D G3DSA:3.40.50.620 41 183 3.7E-10 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L01_05540 0bed1a106c59f411ee5e453fb68fc09b 300 PIRSF PIRSF017066 1 100 1.4E-18 T 23-10-2018 IPR016682 Flagella accessory protein D, predicted, archaeal A3L01_05540 0bed1a106c59f411ee5e453fb68fc09b 300 PIRSF PIRSF017066 110 300 1.1E-62 T 23-10-2018 IPR016682 Flagella accessory protein D, predicted, archaeal A3L01_05540 0bed1a106c59f411ee5e453fb68fc09b 300 Pfam PF04659 Archaeal flagella protein 179 272 1.2E-29 T 23-10-2018 IPR006752 Archaeal flagella protein FlaD/E domain GO:0097588 A3L01_05540 0bed1a106c59f411ee5e453fb68fc09b 300 ProDom PD012942 FLAGELLUM FLAGELLA-RELATED E D ACCESSORY FLAGELLA ARCHAEAL FLAD SIMILAR D 183 284 5.0E-41 T 23-10-2018 IPR006752 Archaeal flagella protein FlaD/E domain GO:0097588 A3L01_04885 29740b3686e8c5b089a083543a183abf 189 Gene3D G3DSA:3.40.5.50 134 188 5.4E-27 T 23-10-2018 A3L01_04885 29740b3686e8c5b089a083543a183abf 189 Gene3D G3DSA:1.20.58.1030 1 114 2.8E-45 T 23-10-2018 A3L01_08035 4037e4cf1b80e418528afdf7e704546e 220 Gene3D G3DSA:3.40.50.11570 3 215 1.1E-68 T 23-10-2018 A3L01_08035 4037e4cf1b80e418528afdf7e704546e 220 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 9 208 1.4E-67 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L01_03185 5e59e2f30a2ec5d2c38cfb9a039176af 114 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 111 8.1E-32 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A3L01_05015 8ca39cdcf95180341701aae3dac8ca54 147 Gene3D G3DSA:1.20.1260.10 2 144 1.5E-8 T 23-10-2018 IPR012347 Ferritin-like A3L01_05015 8ca39cdcf95180341701aae3dac8ca54 147 SUPERFAMILY SSF47240 5 141 1.57E-8 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L01_05015 8ca39cdcf95180341701aae3dac8ca54 147 Pfam PF02915 Rubrerythrin 7 141 8.6E-7 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L01_09585 60cd0d4e05093702678e41aa5baa4ac2 204 Pfam PF01914 MarC family integral membrane protein 6 196 2.1E-30 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A3L01_02025 db4d30b5d406bbe860c3021d798891b9 235 Pfam PF13367 Protease prsW family 31 203 1.0E-31 T 23-10-2018 IPR026898 Protease PrsW GO:0008233 A3L01_02025 db4d30b5d406bbe860c3021d798891b9 235 PIRSF PIRSF016933 4 221 1.6E-32 T 23-10-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 A3L01_04595 2efc6adea1c792e7ad265b1723c137a4 200 Pfam PF13559 Domain of unknown function (DUF4129) 127 184 3.4E-5 T 23-10-2018 IPR025403 Domain of unknown function DUF4129 A3L01_08850 41ae6b1e655ba4fbc759beffd12d8c6c 445 PIRSF PIRSF000521 132 443 2.6E-54 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L01_08850 41ae6b1e655ba4fbc759beffd12d8c6c 445 PIRSF PIRSF000521 2 143 1.1E-7 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L01_08850 41ae6b1e655ba4fbc759beffd12d8c6c 445 SUPERFAMILY SSF53383 34 441 1.15E-122 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L01_08850 41ae6b1e655ba4fbc759beffd12d8c6c 445 Gene3D G3DSA:3.40.640.10 72 340 3.4E-148 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L01_08850 41ae6b1e655ba4fbc759beffd12d8c6c 445 Pfam PF00202 Aminotransferase class-III 35 438 6.1E-112 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L01_08850 41ae6b1e655ba4fbc759beffd12d8c6c 445 Gene3D G3DSA:3.90.1150.10 15 438 3.4E-148 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L01_09415 7cb4a257fc62017ad9e49940326a7cff 247 Pfam PF01925 Sulfite exporter TauE/SafE 8 241 1.8E-41 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A3L01_07940 2dab3cfafc1bc38007263afe94f0c699 193 Gene3D G3DSA:1.10.1760.20 1 193 3.7E-16 T 23-10-2018 A3L01_08815 c5f54ccb3a48ea610b283794e2e85fe2 162 SUPERFAMILY SSF47240 14 159 1.74E-26 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L01_08815 c5f54ccb3a48ea610b283794e2e85fe2 162 Pfam PF02915 Rubrerythrin 18 152 8.2E-16 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L01_08815 c5f54ccb3a48ea610b283794e2e85fe2 162 Gene3D G3DSA:1.20.1260.10 8 158 9.7E-31 T 23-10-2018 IPR012347 Ferritin-like A3L01_02430 39a02f9ac4ff849515ff8237f6966d12 277 Pfam PF00583 Acetyltransferase (GNAT) family 56 141 3.0E-14 T 23-10-2018 IPR000182 GNAT domain A3L01_02430 39a02f9ac4ff849515ff8237f6966d12 277 SUPERFAMILY SSF55729 1 144 4.75E-25 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L01_02430 39a02f9ac4ff849515ff8237f6966d12 277 Gene3D G3DSA:3.40.630.30 1 151 3.2E-23 T 23-10-2018 A3L01_05560 df21b231abccaca3760f4cc1023e6e8a 106 Gene3D G3DSA:1.10.10.10 8 102 5.7E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L01_05560 df21b231abccaca3760f4cc1023e6e8a 106 Pfam PF07381 Winged helix DNA-binding domain (DUF1495) 7 94 1.2E-33 T 23-10-2018 IPR010863 Protein of unknown function DUF1495 A3L01_05560 df21b231abccaca3760f4cc1023e6e8a 106 SUPERFAMILY SSF46785 13 102 1.75E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L01_10155 5516380c2c756eb296bb83cab029b6c4 154 Gene3D G3DSA:3.40.50.2020 1 154 4.3E-53 T 23-10-2018 A3L01_10155 5516380c2c756eb296bb83cab029b6c4 154 SUPERFAMILY SSF53271 3 145 5.77E-35 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L01_10155 5516380c2c756eb296bb83cab029b6c4 154 Pfam PF00156 Phosphoribosyl transferase domain 13 150 3.8E-28 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L01_02555 ce62e615c84f6079032637f358ff64a9 508 Gene3D G3DSA:2.60.40.10 299 383 1.1E-7 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_02555 ce62e615c84f6079032637f358ff64a9 508 SUPERFAMILY SSF49373 308 369 3.77E-7 T 23-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments A3L01_04290 37874a58905c92150aaa500ada71b7c7 315 Gene3D G3DSA:3.20.20.70 5 274 6.4E-27 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L01_04290 37874a58905c92150aaa500ada71b7c7 315 SUPERFAMILY SSF102114 42 219 1.11E-10 T 23-10-2018 A3L01_04290 37874a58905c92150aaa500ada71b7c7 315 PIRSF PIRSF006004 1 306 8.4E-39 T 23-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 A3L01_04290 37874a58905c92150aaa500ada71b7c7 315 Pfam PF04055 Radical SAM superfamily 46 215 7.0E-8 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L01_04995 293b544f2f0906a597437f1b5eedd6fa 119 SUPERFAMILY SSF117916 17 59 4.9E-5 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L01_06045 eda07c2bcb5da672699fa046c3f3280c 128 Pfam PF09868 Uncharacterized protein conserved in archaea (DUF2095) 4 126 5.4E-68 T 23-10-2018 IPR018662 Protein of unknown function DUF2095 A3L01_06625 757fd09524dba24e564ad758ac5b7173 366 Gene3D G3DSA:3.40.50.150 172 351 8.7E-25 T 23-10-2018 A3L01_06625 757fd09524dba24e564ad758ac5b7173 366 Pfam PF01170 Putative RNA methylase family UPF0020 175 320 9.6E-11 T 23-10-2018 IPR000241 Putative RNA methylase domain A3L01_06625 757fd09524dba24e564ad758ac5b7173 366 SUPERFAMILY SSF53335 174 339 2.96E-21 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L01_00770 6b1e687353af393f6d3c14127d00436f 108 Gene3D G3DSA:1.10.287.1080 1 105 1.7E-33 T 23-10-2018 A3L01_00770 6b1e687353af393f6d3c14127d00436f 108 PIRSF PIRSF029826 1 107 2.3E-39 T 23-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 A3L01_00770 6b1e687353af393f6d3c14127d00436f 108 Pfam PF12643 MazG-like family 30 105 1.5E-21 T 23-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 A3L01_00770 6b1e687353af393f6d3c14127d00436f 108 SUPERFAMILY SSF101386 2 105 1.45E-31 T 23-10-2018 A3L01_00905 91635ebdaf4e7738c782e2171321de2e 102 Gene3D G3DSA:2.40.30.10 15 102 2.5E-13 T 23-10-2018 A3L01_00905 91635ebdaf4e7738c782e2171321de2e 102 SUPERFAMILY SSF50447 21 100 4.82E-7 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L01_08675 7eb0d5277ed3878a87bc72dc77928d7e 87 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 82 2.0E-22 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A3L01_06930 6ee5759ca06c44cb901a963eb556c188 87 Pfam PF01169 Uncharacterized protein family UPF0016 6 79 2.6E-22 T 23-10-2018 IPR001727 Gdt1 family A3L01_00875 86a57e0a74b4d60176cda94d32b7ac3d 164 Gene3D G3DSA:1.20.58.2050 1 164 7.7E-82 T 23-10-2018 IPR038437 GINS complex, subunit Psf3 superfamily Reactome: R-HSA-176974 A3L01_00875 86a57e0a74b4d60176cda94d32b7ac3d 164 Pfam PF05916 GINS complex protein 27 147 9.6E-9 T 23-10-2018 IPR021151 GINS subunit, domain A Reactome: R-HSA-176974 A3L01_03470 fbfd9a2f9c4c40802abde88474b04006 234 Pfam PF01040 UbiA prenyltransferase family 3 214 5.4E-23 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A3L01_00715 46d76594675837cb5d3974875f187cf6 132 Pfam PF09999 Uncharacterized protein conserved in archaea (DUF2240) 10 128 3.5E-10 T 23-10-2018 IPR018716 Protein of unknown function DUF2240 A3L01_05925 8a9fb89197d098a9d6c37d70450b1a1b 391 Pfam PF04473 Transglutaminase-like domain 107 253 4.8E-38 T 23-10-2018 IPR007562 Transglutaminase-like domain A3L01_07815 f712e1093088c85adeedc448d0e41973 270 Pfam PF05763 Protein of unknown function (DUF835) 136 263 2.2E-39 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L01_03245 f6b25311dae9330bf757e43262d59668 172 Pfam PF01944 Stage II sporulation protein M 2 167 7.4E-35 T 23-10-2018 IPR002798 Stage II sporulation protein M-like A3L01_02645 3433ac11f1e301532098ef53e32b1840 289 Pfam PF12679 ABC-2 family transporter protein 7 288 3.1E-39 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A3L01_08450 bb86b2c32a35c82bb15ba30b7483d533 531 Pfam PF03553 Na+/H+ antiporter family 158 486 6.8E-75 T 23-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A3L01_00180 372e9a8b594a9a023f2290d4959dff53 208 Pfam PF04021 Class III signal peptide 3 29 1.1E-6 T 23-10-2018 IPR007166 Class III signal peptide motif A3L01_09265 205fa8f313499a69aed7d80c0c7201a2 164 SUPERFAMILY SSF54534 2 150 3.93E-49 T 23-10-2018 A3L01_09265 205fa8f313499a69aed7d80c0c7201a2 164 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 147 1.4E-23 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A3L01_09265 205fa8f313499a69aed7d80c0c7201a2 164 Gene3D G3DSA:3.10.50.80 2 152 1.1E-55 T 23-10-2018 A3L01_09260 b2cd1211962b1a43b0d4979647361d31 300 Gene3D G3DSA:1.20.81.30 88 206 2.0E-6 T 23-10-2018 A3L01_09260 b2cd1211962b1a43b0d4979647361d31 300 Pfam PF00482 Type II secretion system (T2SS), protein F 102 226 7.0E-16 T 23-10-2018 IPR018076 Type II secretion system F domain A3L01_04765 d137ca1750fa503ac3e3f10d95b24155 426 Gene3D G3DSA:1.20.1530.20 12 422 1.2E-16 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L01_04765 d137ca1750fa503ac3e3f10d95b24155 426 Pfam PF00999 Sodium/hydrogen exchanger family 20 420 2.2E-43 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L01_07625 82fae46f68985a704b70c8c698f6b675 121 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 4 108 7.6E-26 T 23-10-2018 IPR019277 Protein of unknown function DUF2304 A3L01_08390 d333b9c794bcdd8a7dce31a24b39bd2a 98 Pfam PF09876 Predicted metal-binding protein (DUF2103) 5 93 8.6E-22 T 23-10-2018 IPR018664 Protein of unknown function DUF2103, metal-binding A3L01_00680 6f6d1313a37724616134ac09a95c7a43 166 SUPERFAMILY SSF51126 39 121 1.76E-12 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor A3L01_02845 11bffc62ec066622ed415da2196f548b 459 SUPERFAMILY SSF161070 5 367 3.4E-7 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 A3L01_02220 4e83534f3dc86df3cfd41b6486cea502 402 SUPERFAMILY SSF53743 1 281 5.23E-39 T 23-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 A3L01_08435 9c9f73ec463516bbb627338bc209910e 247 Pfam PF13367 Protease prsW family 47 186 9.8E-5 T 23-10-2018 IPR026898 Protease PrsW GO:0008233 A3L01_10175 98dafb549d7226c496965a84f6090859 197 Pfam PF12389 Camelysin metallo-endopeptidase 4 162 3.2E-5 T 23-10-2018 IPR022121 Peptidase M73, camelysin A3L01_03535 128b91779f69634aac2de6afd36b1257 285 Pfam PF01435 Peptidase family M48 71 276 7.4E-24 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A3L01_03535 128b91779f69634aac2de6afd36b1257 285 Gene3D G3DSA:3.30.2010.10 65 151 1.2E-20 T 23-10-2018 A3L01_02505 9a0a5862befb6affed968bae78df3f87 371 Pfam PF05763 Protein of unknown function (DUF835) 236 368 9.5E-35 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L01_03195 bfebaa110f7202991041ce7f090828fa 94 Pfam PF13244 Domain of unknown function (DUF4040) 14 79 8.8E-20 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A3L01_00915 ac41b5178dedb61351626644e4696110 221 Gene3D G3DSA:3.40.50.11570 2 216 2.9E-59 T 23-10-2018 A3L01_00915 ac41b5178dedb61351626644e4696110 221 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 8 213 7.4E-63 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L01_04640 be15e9a5fcac6169da247a3e698da157 273 Pfam PF00950 ABC 3 transport family 4 266 5.2E-27 T 23-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 A3L01_04640 be15e9a5fcac6169da247a3e698da157 273 SUPERFAMILY SSF81345 4 272 7.19E-19 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L01_10315 5407160600210f1d9b668779894113a9 59 Pfam PF07754 Domain of unknown function (DUF1610) 10 33 2.5E-14 T 23-10-2018 IPR011668 Domain of unknown function DUF1610 A3L01_08175 8cd3da026fe2588950927bf2e5583bfe 320 Pfam PF01384 Phosphate transporter family 19 307 4.3E-70 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A3L01_08765 cac8e793daaeb7125e5ab9984c187630 155 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 5 139 2.9E-25 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A3L01_07855 fce0441a8af39c8f9aeaf6a01f99faef 337 Pfam PF01032 FecCD transport family 13 329 8.2E-84 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A3L01_07855 fce0441a8af39c8f9aeaf6a01f99faef 337 SUPERFAMILY SSF81345 4 329 4.84E-76 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L01_07855 fce0441a8af39c8f9aeaf6a01f99faef 337 Gene3D G3DSA:1.10.3470.10 2 334 7.5E-91 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L01_03140 5c3a51e7474abee228185b89b2c9fc35 191 Pfam PF06195 Protein of unknown function (DUF996) 33 163 3.3E-28 T 23-10-2018 IPR010397 Protein of unknown function DUF996 A3L01_01315 14eb9201931703e1d0501f7874e9f619 166 Pfam PF03692 Putative zinc- or iron-chelating domain 25 131 4.2E-20 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein A3L01_08800 aaeff6fa8e320c2f31dbeb04679a47d4 321 Pfam PF00146 NADH dehydrogenase 17 317 1.8E-65 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_08800 aaeff6fa8e320c2f31dbeb04679a47d4 321 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 200 213 - T 23-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_01775 2f09d67c9cbafad1e9604548ec15beed 59 Gene3D G3DSA:3.30.300.20 5 58 7.5E-9 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L01_01775 2f09d67c9cbafad1e9604548ec15beed 59 Pfam PF07650 KH domain 7 56 7.0E-6 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L01_01775 2f09d67c9cbafad1e9604548ec15beed 59 SUPERFAMILY SSF54814 14 57 1.61E-7 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L01_03170 31abab6e831967a87e7e155de7898834 297 Pfam PF00146 NADH dehydrogenase 11 296 1.0E-60 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_08585 fa85cbc020550757e150edd5a01ba290 465 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 304 385 2.0E-7 T 23-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase A3L01_08485 363416da88b29b801a89896db3b3ed21 224 Pfam PF04172 LrgB-like family 9 221 1.7E-73 T 23-10-2018 IPR007300 CidB/LrgB family A3L01_08485 363416da88b29b801a89896db3b3ed21 224 TIGRFAM TIGR00659 TIGR00659: TIGR00659 family protein 6 223 8.5E-82 T 23-10-2018 IPR005261 Conserved hypothetical protein CHP00659 A3L01_01830 3dd0053dd6d5f3d3933b6af0601a6cbc 82 ProDom PD486863 PRECURSOR CBIM SIGNAL COBALT MEMBRANE VITAMIN B12 BIOSYNTHESIS COBALAMIN ABC-TYPE 23 81 0.003 T 23-10-2018 A3L01_08695 043aaaaf0b8615efd2d7d0508810ab48 148 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 8 134 3.9E-26 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A3L01_09770 fd44b2b234ff4141c01c24bde734be6d 171 Pfam PF03692 Putative zinc- or iron-chelating domain 16 126 1.6E-16 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein A3L01_04650 c22f9e5d637767c22031ac050461e76f 461 Pfam PF09594 Glycosyltransferase family 87 180 314 3.7E-5 T 23-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 A3L01_03745 e98d90b2c26d8f5b5735f35d91509a60 200 Pfam PF02517 CAAX protease self-immunity 111 188 1.1E-8 T 23-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A3L01_01280 d13b073f97eae881e2eb94ead1557b64 99 Pfam PF04930 FUN14 family 12 96 1.6E-14 T 23-10-2018 IPR007014 FUN14 A3L01_08730 c149183d42064008094415052cb9f0df 329 Pfam PF00146 NADH dehydrogenase 13 319 2.4E-61 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L01_01615 9c78eb198be341f47cd844a7391011dc 99 Pfam PF04242 Protein of unknown function (DUF424) 7 97 7.4E-32 T 23-10-2018 IPR007355 Protein of unknown function DUF424 A3L01_01615 9c78eb198be341f47cd844a7391011dc 99 Gene3D G3DSA:3.30.1860.10 1 97 1.7E-34 T 23-10-2018 A3L01_07295 d642fb00b7d129aed9b163fae1659701 213 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 3 207 5.6E-64 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A3L01_07295 d642fb00b7d129aed9b163fae1659701 213 Pfam PF01914 MarC family integral membrane protein 7 211 3.3E-61 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A3L01_03190 d8c361dbe2da5a95d45191c18e753722 235 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 98 221 1.6E-23 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A3L01_07440 fe71ed9c644127024703499c6fb499a6 147 Pfam PF13576 Pentapeptide repeats (9 copies) 75 122 2.4E-14 T 23-10-2018 IPR001646 Pentapeptide repeat A3L01_08615 b56ee8bd599dfe29ab4ba6cc2cd61773 215 SUPERFAMILY SSF56112 9 154 1.5E-12 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A3L01_08395 f31d1bc44eb3a9d2c4b7d1b8010a91cc 211 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 5 188 1.4E-41 T 23-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 A3L01_08105 101c866291e5c9b711ead3cbd29331ce 284 Pfam PF05681 Fumarate hydratase (Fumerase) 4 270 6.9E-95 T 23-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 A3L01_08105 101c866291e5c9b711ead3cbd29331ce 284 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 3 273 2.1E-121 T 23-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 A3L01_03820 d3609ea0010ef49b2effc195306c81bd 264 SUPERFAMILY SSF55961 3 128 5.01E-7 T 23-10-2018 A3L01_08685 d8b78bfadfcc29260fe00de4dd373bde 88 Pfam PF13244 Domain of unknown function (DUF4040) 17 82 3.8E-17 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A3L01_10005 66e8870e7ba83470071b8fdf381dbc8e 102 Gene3D G3DSA:3.30.720.70 1 102 2.3E-42 T 23-10-2018 A3L01_05415 f3dc99e05303e2c0964b18cf30f605c7 266 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 248 266 4.0E-5 T 23-10-2018 IPR027552 CGP-CTERM domain A3L01_03480 0b5fa13965e9a841c50b9259d0270c6c 249 Gene3D G3DSA:3.40.50.300 5 243 7.4E-71 T 23-10-2018 A3L01_04425 4f5945b163d47115e3b9e1abae9ff7bb 291 Gene3D G3DSA:3.40.50.12090 28 123 3.4E-6 T 23-10-2018 A3L01_09665 d17c406f6b5bd5128301f058e78bbf55 1077 Gene3D G3DSA:2.60.40.10 631 733 8.6E-9 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L01_05310 8e05cff4d34fe5ac55c798ea406497a9 143 Pfam PF09828 Chromate resistance exported protein 3 134 1.8E-47 T 23-10-2018 IPR018634 Chromate resistance exported protein A3L01_03710 bb486ed761b9fc2fae6f89fe6658d51a 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 277 1.6E-34 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A3L01_02590 593b86599822a373a07713db5df81a0d 210 Pfam PF09840 Uncharacterized protein conserved in archaea (DUF2067) 10 197 8.3E-51 T 23-10-2018 IPR019202 Protein of unknown function DUF2067 A3L01_07350 42925b9cd1da031e5a8fe1aba94bc0d1 150 Pfam PF11848 Domain of unknown function (DUF3368) 102 146 1.9E-16 T 23-10-2018 IPR021799 Protein of unknown function DUF3368 A3L01_04830 7805bad62ed941a70c11180b5a80b94a 153 Pfam PF06695 Putative small multi-drug export protein 17 143 7.3E-31 T 23-10-2018 IPR009577 Putative small multi-drug export A3L01_05530 4df915f88c2ad23d7ff37606a6e108a6 149 Pfam PF01917 Archaebacterial flagellin 2 145 2.7E-17 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 A3L01_04235 0436c67632f5d9cc6c2925b81246cda5 364 Pfam PF05763 Protein of unknown function (DUF835) 233 363 7.4E-31 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L01_09275 bd72214b52e6303683d37c3de648458e 263 Pfam PF13559 Domain of unknown function (DUF4129) 190 254 2.8E-8 T 23-10-2018 IPR025403 Domain of unknown function DUF4129 A3L01_08280 dfa5156f33ae9173605b21771ae3da2a 197 PIRSF PIRSF004897 1 165 1.3E-46 T 23-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type A3L01_09330 c6c964cc21f74cb35aae4f46afaa0696 680 Pfam PF04312 Protein of unknown function (DUF460) 222 362 4.4E-49 T 23-10-2018 IPR007408 Protein of unknown function DUF460 A3L01_10145 5f42a3deb060b1272a4bb0715049da94 439 SUPERFAMILY SSF52540 13 227 7.14E-15 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L01_10145 5f42a3deb060b1272a4bb0715049da94 439 Pfam PF13173 AAA domain 43 165 8.2E-21 T 23-10-2018 A3L01_06755 954fab7c43e93be5ab07375e24a59be0 492 Pfam PF02952 L-fucose isomerase, C-terminal domain 348 478 9.9E-27 T 23-10-2018 IPR015888 L-fucose isomerase, C-terminal GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 A3L01_06755 954fab7c43e93be5ab07375e24a59be0 492 SUPERFAMILY SSF53743 50 330 3.27E-42 T 23-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861