locus-tag	class	description
A3L02_00025	COG0535	radical SAM domain protein
A3L02_00070	COG0142	geranyltranstransferase activity
A3L02_00075	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A3L02_00090	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A3L02_00100	COG1355	regulation of microtubule-based process
A3L02_00110	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
A3L02_00135	COG0585	pseudouridine synthase activity
A3L02_00150	COG0017	Asparaginyl-tRNA synthetase
A3L02_00160	COG1418	mRNA catabolic process
A3L02_00175	COG0546	phosphoglycolate phosphatase activity
A3L02_00185	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
A3L02_00210	COG1110	DNA topoisomerase II activity
A3L02_00265	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A3L02_00285	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A3L02_00300	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A3L02_00315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A3L02_00325	COG1522	sequence-specific DNA binding
A3L02_00335	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A3L02_00340	COG0534	Mate efflux family protein
A3L02_00345	COG0574	Belongs to the PEP-utilizing enzyme family
A3L02_00345	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A3L02_00360	COG1404	Belongs to the peptidase S8 family
A3L02_00375	COG0446	pyridine nucleotide-disulphide oxidoreductase
A3L02_00390	COG2414	aldehyde ferredoxin oxidoreductase
A3L02_00405	COG0731	radical SAM domain protein
A3L02_00405	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L02_00425	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A3L02_00445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A3L02_00460	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A3L02_00465	COG0409	Hydrogenase expression formation protein
A3L02_00470	COG0298	carbon dioxide binding
A3L02_00475	COG0746	molybdenum cofactor guanylyltransferase activity
A3L02_00485	COG0489	protein tyrosine kinase activity
A3L02_00500	COG1234	tRNA 3'-trailer cleavage
A3L02_00515	COG2140	Oxalate decarboxylase
A3L02_00555	COG1122	ATPase activity
A3L02_00560	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A3L02_00570	COG0310	cobalt ion transport
A3L02_00585	COG1185	polyribonucleotide nucleotidyltransferase activity
A3L02_00620	COG0436	Aminotransferase
A3L02_00670	COG0052	Belongs to the universal ribosomal protein uS2 family
A3L02_00675	COG0148	phosphopyruvate hydratase activity
A3L02_00695	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A3L02_00700	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A3L02_00705	COG0200	Binds to the 23S rRNA
A3L02_00715	COG0202	RNA polymerase activity
A3L02_00725	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A3L02_00730	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A3L02_00740	COG2813	Specifically methylates the guanine in position
A3L02_00745	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A3L02_00750	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
A3L02_00760	COG1102	Psort location Cytoplasmic, score
A3L02_00780	COG0201	protein transport
A3L02_00785	COG0200	Binds to the 23S rRNA
A3L02_00795	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A3L02_00800	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A3L02_00820	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A3L02_00830	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A3L02_00840	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
A3L02_00845	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A3L02_00850	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A3L02_00860	COG0023	Translation Initiation Factor
A3L02_00865	COG0255	Belongs to the universal ribosomal protein uL29 family
A3L02_00870	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A3L02_00875	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A3L02_00880	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A3L02_00885	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A3L02_00890	COG0089	rRNA binding
A3L02_00895	COG0088	Forms part of the polypeptide exit tunnel
A3L02_00900	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A3L02_00925	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A3L02_00935	COG0017	Asparaginyl-tRNA synthetase
A3L02_00960	COG0543	2 iron, 2 sulfur cluster binding
A3L02_00970	COG3259	Nickel-dependent hydrogenase
A3L02_00995	COG0430	RNA-3'-phosphate cyclase activity
A3L02_01030	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3L02_01040	COG5016	pyruvate
A3L02_01040	COG0511	ligase activity, forming carbon-carbon bonds
A3L02_01045	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
A3L02_01050	COG2239	Acts as a magnesium transporter
A3L02_01075	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
A3L02_01080	COG1185	polyribonucleotide nucleotidyltransferase activity
A3L02_01095	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
A3L02_01115	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L02_01140	COG1335	isochorismatase
A3L02_01150	COG2050	protein possibly involved in aromatic compounds catabolism
A3L02_01150	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L02_01155	COG1695	Transcriptional regulator
A3L02_01180	COG1185	polyribonucleotide nucleotidyltransferase activity
A3L02_01205	COG0417	DNA replication proofreading
A3L02_01215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L02_01215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A3L02_01220	COG2078	PFAM AMMECR1 domain protein
A3L02_01225	COG0011	TIGRFAM Protein of
A3L02_01250	COG1178	ABC-type Fe3 transport system permease component
A3L02_01255	COG3842	ATPase activity
A3L02_01325	COG0516	GMP reductase activity
A3L02_01325	COG0517	IMP dehydrogenase activity
A3L02_01330	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A3L02_01335	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A3L02_01350	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A3L02_01365	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A3L02_01365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A3L02_01365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A3L02_01370	COG1105	Belongs to the carbohydrate kinase PfkB family
A3L02_01375	COG1349	DNA-binding transcription factor activity
A3L02_01385	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
A3L02_01390	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
A3L02_01395	COG3383	formate dehydrogenase (NAD+) activity
A3L02_01400	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A3L02_01410	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A3L02_01415	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
A3L02_01420	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A3L02_01425	COG0151	Belongs to the GarS family
A3L02_01440	COG0047	phosphoribosylformylglycinamidine synthase activity
A3L02_01475	COG1131	(ABC) transporter
A3L02_01490	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A3L02_01495	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A3L02_01495	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A3L02_01500	COG0307	riboflavin synthase, alpha
A3L02_01505	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A3L02_01505	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A3L02_01510	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
A3L02_01520	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A3L02_01520	COG0519	Catalyzes the synthesis of GMP from XMP
A3L02_01530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A3L02_01530	COG0519	Catalyzes the synthesis of GMP from XMP
A3L02_01595	COG2890	protein-(glutamine-N5) methyltransferase activity
A3L02_01620	COG0557	exoribonuclease II activity
A3L02_01705	COG2046	Belongs to the sulfate adenylyltransferase family
A3L02_01790	COG0438	transferase activity, transferring glycosyl groups
A3L02_01825	COG0438	transferase activity, transferring glycosyl groups
A3L02_01865	COG0714	Associated with various cellular activities
A3L02_01915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A3L02_01915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A3L02_01930	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A3L02_01975	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A3L02_01980	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
A3L02_01985	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
A3L02_01990	COG0351	phosphomethylpyrimidine kinase
A3L02_01990	COG1992	Thiamine-phosphate synthase
A3L02_02005	COG0215	cysteine-tRNA ligase activity
A3L02_02055	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A3L02_02060	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
A3L02_02090	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A3L02_02090	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L02_02095	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L02_02105	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A3L02_02105	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L02_02110	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L02_02165	COG0720	synthase
A3L02_02190	COG0730	response to heat
A3L02_02195	COG0730	response to heat
A3L02_02200	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A3L02_02205	COG0442	prolyl-tRNA aminoacylation
A3L02_02210	COG2192	nodulation
A3L02_02215	COG0436	Aminotransferase
A3L02_02225	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A3L02_02235	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
A3L02_02245	COG1515	deoxyribonuclease V activity
A3L02_02265	COG0569	domain protein
A3L02_02280	COG1476	TRANSCRIPTIONal
A3L02_02290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A3L02_02340	COG1120	ATPase activity
A3L02_02365	COG1131	(ABC) transporter
A3L02_02425	COG1694	Mazg nucleotide pyrophosphohydrolase
A3L02_02430	COG1522	sequence-specific DNA binding
A3L02_02435	COG1836	PFAM Integral membrane protein DUF92
A3L02_02460	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A3L02_02520	COG0018	arginyl-trna synthetase
A3L02_02540	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A3L02_02555	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L02_02565	COG1863	multisubunit Na H antiporter MnhE subunit
A3L02_02570	COG2212	antiporter activity
A3L02_02575	COG1320	monovalent cation:proton antiporter activity
A3L02_02585	COG2111	Na H antiporter
A3L02_02585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A3L02_02590	COG1006	Multisubunit Na H antiporter MnhC subunit
A3L02_02595	COG0651	ATP synthesis coupled electron transport
A3L02_02610	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L02_02615	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L02_02620	COG0649	NAD binding
A3L02_02700	COG0719	Fe-S assembly protein
A3L02_02725	COG2414	aldehyde ferredoxin oxidoreductase
A3L02_02730	COG0719	Fe-S assembly protein
A3L02_02740	COG0396	ATPase activity
A3L02_02750	COG1528	Iron-storage protein
A3L02_02755	COG0301	tRNA thio-modification
A3L02_02760	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A3L02_02765	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A3L02_02770	COG0778	Nitroreductase
A3L02_02795	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L02_02795	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A3L02_02800	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L02_02805	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A3L02_02810	COG0426	domain, Protein
A3L02_02825	COG1592	Rubrerythrin
A3L02_02830	COG1773	rubredoxin
A3L02_02835	COG2033	superoxide reductase activity
A3L02_02905	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A3L02_02920	COG0124	histidyl-tRNA synthetase
A3L02_02925	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A3L02_02935	COG0131	Imidazoleglycerol-phosphate dehydratase
A3L02_02940	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A3L02_02945	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
A3L02_02950	COG0107	imidazoleglycerol-phosphate synthase activity
A3L02_02955	COG0140	phosphoribosyl-ATP diphosphatase activity
A3L02_02955	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A3L02_02960	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A3L02_02970	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A3L02_02975	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A3L02_02980	COG1518	maintenance of DNA repeat elements
A3L02_02985	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A3L02_02995	COG1203	CRISPR-associated helicase, Cas3
A3L02_03000	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L02_03010	COG1301	dicarboxylic acid transport
A3L02_03015	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A3L02_03015	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A3L02_03020	COG1830	Aldolase
A3L02_03030	COG1966	Carbon starvation protein
A3L02_03045	COG0003	Pfam Anion-transporting ATPase
A3L02_03060	COG2267	carboxylic ester hydrolase activity
A3L02_03065	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A3L02_03070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A3L02_03090	COG0489	protein tyrosine kinase activity
A3L02_03120	COG1028	Short-chain dehydrogenase reductase Sdr
A3L02_03145	COG1342	Belongs to the UPF0251 family
A3L02_03150	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A3L02_03165	COG4109	DRTGG domain
A3L02_03175	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L02_03180	COG0456	acetyltransferase
A3L02_03225	COG2814	Major facilitator Superfamily
A3L02_03230	COG1201	RNA secondary structure unwinding
A3L02_03235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3L02_03240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3L02_03255	COG0084	hydrolase, TatD family'
A3L02_03265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A3L02_03280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A3L02_03285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3L02_03290	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3L02_03300	COG0105	UTP biosynthetic process
A3L02_03335	COG0175	sulfate reduction
A3L02_03355	COG0444	Belongs to the ABC transporter superfamily
A3L02_03360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3L02_03365	COG0601	transmembrane transport
A3L02_03370	COG4166	transmembrane transport
A3L02_03385	COG2723	6-phospho-beta-galactosidase activity
A3L02_03410	COG4221	oxidoreductase activity
A3L02_03425	COG0402	S-adenosylhomocysteine deaminase activity
A3L02_03430	COG0017	Asparaginyl-tRNA synthetase
A3L02_03475	COG4143	(ABC) transporter
A3L02_03495	COG1444	tRNA N-acetyltransferase activity
A3L02_03500	COG4946	Tricorn protease homolog
A3L02_03500	COG0823	Involved in the tonB-independent uptake of proteins
A3L02_03500	COG1506	peptidase
A3L02_03510	COG1268	BioY protein
A3L02_03515	COG1122	ATPase activity
A3L02_03555	COG1522	sequence-specific DNA binding
A3L02_03575	COG1178	ABC-type Fe3 transport system permease component
A3L02_03580	COG3842	ATPase activity
A3L02_03605	COG0126	phosphoglycerate kinase activity
A3L02_03635	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A3L02_03665	COG1042	CoA-binding domain protein
A3L02_03665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L02_03665	COG0045	succinate-CoA ligase (ADP-forming) activity
A3L02_03675	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A3L02_03690	COG0301	tRNA thio-modification
A3L02_03725	COG1489	DNA binding
A3L02_03745	COG1199	ATP-dependent helicase activity
A3L02_03760	COG1216	Glycosyl transferase, family 2
A3L02_03765	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
A3L02_03785	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L02_03785	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A3L02_03800	COG0315	cyclic pyranopterin monophosphate synthase activity
A3L02_03810	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A3L02_03815	COG0515	serine threonine protein kinase
A3L02_03830	COG1028	Short-chain dehydrogenase reductase Sdr
A3L02_03835	COG1899	peptidyl-lysine modification to peptidyl-hypusine
A3L02_03850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L02_03860	COG1078	dGTPase activity
A3L02_03890	COG0521	Mo-molybdopterin cofactor biosynthetic process
A3L02_03900	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
A3L02_03910	COG1492	cobalamin metabolic process
A3L02_03930	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
A3L02_03950	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
A3L02_03955	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A3L02_03970	COG0525	valine-tRNA ligase activity
A3L02_03985	COG2076	Multidrug Resistance protein
A3L02_03995	COG0602	queuosine metabolic process
A3L02_04000	COG1328	CTP reductase activity
A3L02_04000	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A3L02_04005	COG2264	protein methyltransferase activity
A3L02_04020	COG0312	modulator of DNA gyrase
A3L02_04030	COG1794	racemase activity, acting on amino acids and derivatives
A3L02_04040	COG0012	GTP binding
A3L02_04065	COG0163	prenyltransferase activity
A3L02_04075	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A3L02_04100	COG0482	sulfurtransferase activity
A3L02_04115	COG0006	proline dipeptidase activity
A3L02_04130	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
A3L02_04140	COG0534	Mate efflux family protein
A3L02_04160	COG0423	glycine-tRNA ligase activity
A3L02_04165	COG2361	Protein of unknown function DUF86
A3L02_04185	COG1872	DUF167
A3L02_04200	COG1122	ATPase activity
A3L02_04220	COG1058	Belongs to the CinA family
A3L02_04220	COG1546	Belongs to the CinA family
A3L02_04225	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L02_04235	COG2096	Adenosyltransferase
A3L02_04270	COG1363	Peptidase, m42
A3L02_04325	COG0543	2 iron, 2 sulfur cluster binding
A3L02_04330	COG0493	'glutamate synthase
A3L02_04330	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A3L02_04350	COG1141	Ferredoxin
A3L02_04355	COG2151	metal-sulfur cluster biosynthetic enzyme
A3L02_04375	COG1404	Belongs to the peptidase S8 family
A3L02_04400	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A3L02_04415	COG0167	dihydroorotate dehydrogenase activity
A3L02_04440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A3L02_04480	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A3L02_04490	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L02_04495	COG1522	sequence-specific DNA binding
A3L02_04500	COG0693	protein deglycase activity
A3L02_04515	COG2095	MarC family integral membrane protein
A3L02_04520	COG1765	OsmC-like protein
A3L02_04530	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A3L02_04535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3L02_04540	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L02_04545	COG0588	phosphoglycerate mutase activity
A3L02_04565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A3L02_04570	COG0183	Belongs to the thiolase family
A3L02_04625	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A3L02_04655	COG0159	tryptophan synthase activity
A3L02_04660	COG0133	tryptophan synthase activity
A3L02_04665	COG0135	phosphoribosylanthranilate isomerase activity
A3L02_04670	COG0512	Glutamine amidotransferase of anthranilate synthase
A3L02_04670	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A3L02_04675	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A3L02_04680	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A3L02_04695	COG3959	Transketolase, thiamine diphosphate binding domain
A3L02_04700	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A3L02_04705	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A3L02_04715	COG0710	3-dehydroquinate dehydratase activity
A3L02_04725	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
A3L02_04740	COG0287	Prephenate dehydrogenase
A3L02_04740	COG1605	Chorismate mutase
A3L02_04745	COG0436	Aminotransferase
A3L02_04760	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A3L02_04780	COG0440	acetolactate synthase activity
A3L02_04785	COG0651	ATP synthesis coupled electron transport
A3L02_04815	COG2212	antiporter activity
A3L02_04820	COG1863	multisubunit Na H antiporter MnhE subunit
A3L02_04825	COG0509	glycine decarboxylation via glycine cleavage system
A3L02_04835	COG0438	transferase activity, transferring glycosyl groups
A3L02_04850	COG0493	'glutamate synthase
A3L02_04855	COG0543	2 iron, 2 sulfur cluster binding
A3L02_04890	COG0601	transmembrane transport
A3L02_04900	COG0444	Belongs to the ABC transporter superfamily
A3L02_04905	COG4608	Belongs to the ABC transporter superfamily
A3L02_04940	COG1131	(ABC) transporter
A3L02_04950	COG1476	TRANSCRIPTIONal
A3L02_04970	COG0483	inositol monophosphate 1-phosphatase activity
A3L02_04980	COG1454	alcohol dehydrogenase
A3L02_04990	COG1984	allophanate hydrolase subunit 2
A3L02_04995	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A3L02_05000	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A3L02_05025	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A3L02_05040	COG0330	HflC and HflK could
A3L02_05045	COG2894	cell division
A3L02_05060	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A3L02_05075	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
A3L02_05105	COG1196	nuclear chromosome segregation
A3L02_05125	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A3L02_05125	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A3L02_05140	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A3L02_05170	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A3L02_05175	COG1993	acr, cog1993
A3L02_05185	COG0668	transmembrane transport
A3L02_05190	COG1794	racemase activity, acting on amino acids and derivatives
A3L02_05205	COG0312	modulator of DNA gyrase
A3L02_05210	COG0312	modulator of DNA gyrase
A3L02_05220	COG0477	Major facilitator Superfamily
A3L02_05280	COG0438	transferase activity, transferring glycosyl groups
A3L02_05300	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A3L02_05340	COG0243	molybdopterin cofactor binding
A3L02_05345	COG0450	alkyl hydroperoxide reductase
A3L02_05390	COG1230	cation diffusion facilitator family transporter
A3L02_05395	COG0450	alkyl hydroperoxide reductase
A3L02_05435	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
A3L02_05455	COG1012	belongs to the aldehyde dehydrogenase family
A3L02_05485	COG1160	GTP binding
A3L02_05510	COG1832	CoA-binding protein
A3L02_05535	COG2379	hydroxypyruvate reductase
A3L02_05545	COG3842	ATPase activity
A3L02_05570	COG0673	inositol 2-dehydrogenase activity
A3L02_05575	COG0463	Glycosyl transferase, family 2
A3L02_05625	COG1435	thymidine kinase activity
A3L02_05630	COG1850	ribulose-bisphosphate carboxylase activity
A3L02_05655	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A3L02_05655	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A3L02_05675	COG1131	(ABC) transporter
A3L02_05685	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A3L02_05685	COG1213	nucleotidyl transferase
A3L02_05700	COG0284	orotidine-5'-phosphate decarboxylase activity
A3L02_05710	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A3L02_05710	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A3L02_05725	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A3L02_05765	COG0501	Belongs to the peptidase M48B family
A3L02_05770	COG2131	deaminase
A3L02_05780	COG0463	Glycosyl transferase, family 2
A3L02_05785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A3L02_05795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L02_05800	COG2814	Major facilitator Superfamily
A3L02_05815	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A3L02_05825	COG1446	asparaginase
A3L02_05835	COG2814	Major facilitator Superfamily
A3L02_05845	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
A3L02_05880	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A3L02_05895	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A3L02_05910	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L02_05920	COG2255	four-way junction helicase activity
A3L02_05925	COG2255	four-way junction helicase activity
A3L02_05930	COG0156	8-amino-7-oxononanoate synthase activity
A3L02_05945	COG0456	acetyltransferase
A3L02_05950	COG0433	COG0433 Predicted ATPase
A3L02_05960	COG0419	ATPase involved in DNA repair
A3L02_05960	COG0419	ATPase involved in DNA repair
A3L02_05980	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A3L02_06010	COG0432	Pfam Uncharacterised protein family UPF0047
A3L02_06020	COG0351	phosphomethylpyrimidine kinase
A3L02_06020	COG1992	Thiamine-phosphate synthase
A3L02_06025	COG0540	Belongs to the ATCase OTCase family
A3L02_06030	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
A3L02_06050	COG0237	dephospho-CoA kinase activity
A3L02_06070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3L02_06105	COG0434	BtpA family
A3L02_06150	COG0312	modulator of DNA gyrase
A3L02_06155	COG0312	modulator of DNA gyrase
A3L02_06160	COG1846	Transcriptional regulator
A3L02_06175	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A3L02_06205	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L02_06210	COG1394	ATPase activity, coupled to movement of substances
A3L02_06215	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
A3L02_06220	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
A3L02_06245	COG1269	ATP hydrolysis coupled proton transport
A3L02_06255	COG0569	domain protein
A3L02_06260	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A3L02_06270	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A3L02_06280	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L02_06315	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L02_06325	COG1573	uracil-dna glycosylase
A3L02_06330	COG1757	Na H antiporter
A3L02_06365	COG1793	dna ligase
A3L02_06375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A3L02_06385	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3L02_06390	COG1522	sequence-specific DNA binding
A3L02_06440	COG1233	COG1233 Phytoene dehydrogenase and related
A3L02_06455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A3L02_06470	COG1980	fructose-bisphosphate aldolase activity
A3L02_06490	COG0463	Glycosyl transferase, family 2
A3L02_06495	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L02_06505	COG2234	aminopeptidase activity
A3L02_06545	COG1695	Transcriptional regulator
A3L02_06555	COG0393	Putative heavy-metal-binding
A3L02_06570	COG2264	protein methyltransferase activity
A3L02_06585	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L02_06585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A3L02_06590	COG0668	transmembrane transport
A3L02_06660	COG0218	Necessary for normal cell division and for the maintenance of normal septation
A3L02_06665	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A3L02_06670	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
A3L02_06730	COG0589	response to stress
A3L02_06735	COG1628	Protein of unknown function DUF99
A3L02_06745	COG1254	Belongs to the acylphosphatase family
A3L02_06755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A3L02_06780	COG0489	protein tyrosine kinase activity
A3L02_06785	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L02_06790	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L02_06800	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L02_06805	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L02_06820	COG0306	phosphate transporter
A3L02_06825	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A3L02_06855	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A3L02_06870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A3L02_06910	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A3L02_06915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A3L02_06950	COG1115	amino acid carrier protein
A3L02_06970	COG0475	glutathione-regulated potassium exporter activity
A3L02_06975	COG0475	glutathione-regulated potassium exporter activity
A3L02_06980	COG2239	Acts as a magnesium transporter
A3L02_06985	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
A3L02_07000	COG0037	tRNA processing
A3L02_07015	COG1449	Belongs to the glycosyl hydrolase 57 family
A3L02_07040	COG4651	solute:proton antiporter activity
A3L02_07040	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A3L02_07045	COG0076	glutamate decarboxylase activity
A3L02_07050	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A3L02_07070	COG1216	Glycosyl transferase, family 2
A3L02_07085	COG0438	transferase activity, transferring glycosyl groups
A3L02_07085	COG0297	glycogen (starch) synthase activity
A3L02_07100	COG1442	glycosyl transferase family 8
A3L02_07100	COG1216	Glycosyl transferase, family 2
A3L02_07115	COG0673	inositol 2-dehydrogenase activity
A3L02_07120	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A3L02_07125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A3L02_07130	COG0037	tRNA processing
A3L02_07160	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
A3L02_07165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3L02_07175	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A3L02_07195	COG0714	Associated with various cellular activities
A3L02_07215	COG1047	Peptidyl-prolyl cis-trans
A3L02_07250	COG1160	GTP binding
A3L02_07255	COG0116	Belongs to the methyltransferase superfamily
A3L02_07255	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A3L02_07260	COG0179	Fumarylacetoacetate (FAA) hydrolase
A3L02_07270	COG0463	Glycosyl transferase, family 2
A3L02_07295	COG0180	Tryptophanyl-tRNA synthetase
A3L02_07305	COG0640	Transcriptional regulator
A3L02_07330	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A3L02_07330	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A3L02_07340	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
A3L02_07340	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A3L02_07355	COG0402	S-adenosylhomocysteine deaminase activity
A3L02_07375	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A3L02_07390	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
A3L02_07510	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A3L02_07520	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A3L02_07530	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A3L02_07530	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L02_07570	COG0235	Class ii aldolase
A3L02_07600	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
A3L02_07605	COG1451	nucleotide metabolic process
A3L02_07645	COG0095	Lipoate-protein ligase
A3L02_07650	COG0681	Belongs to the peptidase S26 family
A3L02_07690	COG4946	Tricorn protease homolog
A3L02_07690	COG1506	peptidase
A3L02_07690	COG0823	Involved in the tonB-independent uptake of proteins
A3L02_07715	COG0306	phosphate transporter
A3L02_07735	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A3L02_07740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3L02_07750	COG2212	antiporter activity
A3L02_07755	COG1320	monovalent cation:proton antiporter activity
A3L02_07775	COG0713	ATP synthesis coupled electron transport
A3L02_07780	COG0651	ATP synthesis coupled electron transport
A3L02_07790	COG3260	NADH ubiquinone oxidoreductase 20
A3L02_07795	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L02_07795	COG0649	NAD binding
A3L02_07795	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L02_07800	COG3261	NADH dehydrogenase
A3L02_07800	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
A3L02_07805	COG0650	Formate hydrogenlyase subunit 4
A3L02_07850	COG0492	ferredoxin-NADP+ reductase activity
A3L02_07860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A3L02_07875	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A3L02_07885	COG0148	phosphopyruvate hydratase activity
A3L02_07900	COG1522	sequence-specific DNA binding
A3L02_07905	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A3L02_07925	COG0314	molybdopterin synthase activity
A3L02_07935	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A3L02_07940	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
A3L02_07945	COG0482	sulfurtransferase activity
A3L02_07960	COG0543	2 iron, 2 sulfur cluster binding
A3L02_07965	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A3L02_07975	COG0601	transmembrane transport
A3L02_07980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3L02_07985	COG0444	Belongs to the ABC transporter superfamily
A3L02_07990	COG4608	Belongs to the ABC transporter superfamily
A3L02_08010	COG0174	glutamine synthetase
A3L02_08045	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L02_08065	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A3L02_08080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3L02_08085	COG1297	OPT oligopeptide transporter protein
A3L02_08095	COG1234	tRNA 3'-trailer cleavage
A3L02_08100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3L02_08105	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A3L02_08110	COG3842	ATPase activity
A3L02_08120	COG3833	ABC-type maltose transport systems, permease component
A3L02_08125	COG1175	transmembrane transport
A3L02_08140	COG1378	Sugar-specific transcriptional regulator TrmB
A3L02_08145	COG0297	glycogen (starch) synthase activity
A3L02_08175	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L02_08180	COG1201	RNA secondary structure unwinding
A3L02_08190	COG1215	transferase activity, transferring glycosyl groups
A3L02_08225	COG1739	Uncharacterized protein family UPF0029
A3L02_08230	COG1129	ABC transporter
A3L02_08275	COG2403	cyclic 2,3-diphosphoglycerate synthetase activity
A3L02_08300	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3L02_08305	COG2414	aldehyde ferredoxin oxidoreductase
A3L02_08320	COG0051	transcription antitermination factor activity, RNA binding
A3L02_08325	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A3L02_08330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A3L02_08335	COG1078	dGTPase activity
A3L02_08360	COG1469	GTP cyclohydrolase I activity
A3L02_08370	COG1401	restriction endodeoxyribonuclease activity
A3L02_08415	COG1121	(ABC) transporter
A3L02_08425	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A3L02_08445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A3L02_08460	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A3L02_08465	COG0011	TIGRFAM Protein of
A3L02_08480	COG0424	maF-like protein
A3L02_08490	COG4956	integral membrane protein (PIN domain superfamily)
A3L02_08495	COG2894	cell division
A3L02_08505	COG0367	asparagine synthase
A3L02_08520	COG0009	L-threonylcarbamoyladenylate synthase
A3L02_08545	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A3L02_08550	COG0303	'Molybdopterin
A3L02_08560	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L02_08595	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A3L02_08600	COG0045	succinate-CoA ligase (ADP-forming) activity
A3L02_08600	COG1042	CoA-binding domain protein
A3L02_08600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L02_08680	COG1793	dna ligase
A3L02_08680	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A3L02_08690	COG0071	Belongs to the small heat shock protein (HSP20) family
A3L02_08740	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A3L02_08745	COG0778	Nitroreductase
A3L02_08765	COG1132	(ABC) transporter
A3L02_08770	COG1132	(ABC) transporter
A3L02_08775	COG1051	belongs to the nudix hydrolase family
A3L02_08775	COG1056	cytidyltransferase-related domain
A3L02_08825	COG0560	Phosphoserine phosphatase
A3L02_08830	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A3L02_08895	COG2264	protein methyltransferase activity
A3L02_08940	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
A3L02_08945	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
A3L02_08975	COG0714	Associated with various cellular activities
A3L02_08985	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A3L02_08990	COG0725	ABC transporter, periplasmic molybdate-binding protein
A3L02_09010	COG1881	PFAM PEBP family protein
A3L02_09015	COG1028	Short-chain dehydrogenase reductase Sdr
A3L02_09040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L02_09045	COG0602	queuosine metabolic process
A3L02_09080	COG0704	Plays a role in the regulation of phosphate uptake
A3L02_09090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A3L02_09100	COG0573	inorganic phosphate transmembrane transporter activity
A3L02_09105	COG1082	Xylose isomerase domain protein TIM barrel
A3L02_09125	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A3L02_09125	COG0359	binds to the 23S rRNA
A3L02_09140	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3L02_09140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3L02_09155	COG0656	L-ascorbic acid biosynthetic process
A3L02_09160	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
A3L02_09175	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
A3L02_09180	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A3L02_09225	COG0010	Belongs to the arginase family
A3L02_09255	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A3L02_09295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A3L02_09305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A3L02_09335	COG0252	asparaginase activity
A3L02_09340	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A3L02_09350	COG2894	cell division
A3L02_09355	COG1063	alcohol dehydrogenase
A3L02_09370	COG0101	tRNA pseudouridine synthase activity
A3L02_09375	COG0556	nucleotide-excision repair
A3L02_09385	COG4152	abc transporter atp-binding protein
A3L02_09415	COG0628	permease
A3L02_09510	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A3L02_09525	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A3L02_09560	COG1122	ATPase activity
A3L02_09565	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A3L02_09570	COG0024	Methionine aminopeptidase
A3L02_09580	COG0516	GMP reductase activity
A3L02_09580	COG0517	IMP dehydrogenase activity
A3L02_09590	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A3L02_09605	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L02_09620	COG0504	CTP synthase activity
A3L02_09645	COG0717	Belongs to the dCTP deaminase family
A3L02_09655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A3L02_09670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A3L02_09670	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A3L02_09680	COG0058	SHG alpha-glucan phosphorylase activity
A3L02_09700	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A3L02_09710	COG2271	Major facilitator Superfamily
A3L02_09715	COG2814	Major facilitator Superfamily
A3L02_09720	COG0584	glycerophosphoryl diester phosphodiesterase
A3L02_09725	COG0584	glycerophosphoryl diester phosphodiesterase
A3L02_09735	COG2339	peptidase activity
A3L02_09760	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3L02_09765	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3L02_09795	COG0081	regulation of translation
A3L02_09800	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A3L02_09815	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A3L02_09865	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A3L02_09870	COG0049	tRNA binding
A3L02_09890	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A3L02_09895	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A3L02_09900	COG0085	RNA polymerase activity
A3L02_09930	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A3L02_09935	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
A3L02_09950	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A3L02_09960	COG0733	neurotransmitter:sodium symporter activity
A3L02_09970	COG0347	Belongs to the P(II) protein family
A3L02_09975	COG1543	Belongs to the glycosyl hydrolase 57 family
A3L02_09990	COG0864	Transcriptional regulator
A3L02_10000	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
A3L02_10020	COG0006	proline dipeptidase activity
A3L02_10025	COG0495	leucyl-tRNA aminoacylation