A3L04_06555 b94031f185ee83f3313a15f796ff21e0 266 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 17 24 7.3E-44 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L04_06555 b94031f185ee83f3313a15f796ff21e0 266 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 30 51 7.3E-44 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L04_06555 b94031f185ee83f3313a15f796ff21e0 266 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 117 131 7.3E-44 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L04_06555 b94031f185ee83f3313a15f796ff21e0 266 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 61 69 7.3E-44 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L04_06555 b94031f185ee83f3313a15f796ff21e0 266 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 87 104 7.3E-44 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L04_06555 b94031f185ee83f3313a15f796ff21e0 266 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 162 179 7.3E-44 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L04_06555 b94031f185ee83f3313a15f796ff21e0 266 Gene3D G3DSA:3.40.1190.20 2 266 2.2E-99 T 23-10-2018 IPR029056 Ribokinase-like A3L04_06555 b94031f185ee83f3313a15f796ff21e0 266 Pfam PF02110 Hydroxyethylthiazole kinase family 9 252 1.6E-84 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L04_06555 b94031f185ee83f3313a15f796ff21e0 266 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 9 255 4.3E-99 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L04_06555 b94031f185ee83f3313a15f796ff21e0 266 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 11 256 33.463 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L04_06555 b94031f185ee83f3313a15f796ff21e0 266 SUPERFAMILY SSF53613 5 262 1.8E-69 T 23-10-2018 IPR029056 Ribokinase-like A3L04_06555 b94031f185ee83f3313a15f796ff21e0 266 PIRSF PIRSF000513 3 264 8.1E-104 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L04_08295 389ffabd68d12e2cdd30f16727be0483 572 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_08295 389ffabd68d12e2cdd30f16727be0483 572 SUPERFAMILY SSF52540 328 549 6.56E-80 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_08295 389ffabd68d12e2cdd30f16727be0483 572 Gene3D G3DSA:1.20.1560.10 2 322 1.6E-93 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A3L04_08295 389ffabd68d12e2cdd30f16727be0483 572 Gene3D G3DSA:3.40.50.300 332 566 2.3E-82 T 23-10-2018 A3L04_08295 389ffabd68d12e2cdd30f16727be0483 572 Pfam PF00664 ABC transporter transmembrane region 22 291 1.6E-61 T 23-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A3L04_08295 389ffabd68d12e2cdd30f16727be0483 572 Pfam PF00005 ABC transporter 352 500 2.3E-34 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_08295 389ffabd68d12e2cdd30f16727be0483 572 SUPERFAMILY SSF90123 9 319 4.05E-82 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A3L04_08295 389ffabd68d12e2cdd30f16727be0483 572 SMART SM00382 361 547 4.7E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_01350 30eb22795e6ec666f1703ebae30bbc32 140 SUPERFAMILY SSF56276 3 117 1.67E-42 T 23-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 A3L04_01350 30eb22795e6ec666f1703ebae30bbc32 140 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 3 113 6.8E-46 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A3L04_01350 30eb22795e6ec666f1703ebae30bbc32 140 Pfam PF02675 S-adenosylmethionine decarboxylase 7 113 6.0E-38 T 23-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A3L04_01350 30eb22795e6ec666f1703ebae30bbc32 140 Gene3D G3DSA:3.30.360.110 1 62 1.3E-20 T 23-10-2018 A3L04_01350 30eb22795e6ec666f1703ebae30bbc32 140 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 1 117 32.333 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A3L04_01350 30eb22795e6ec666f1703ebae30bbc32 140 Gene3D G3DSA:3.30.160.750 63 129 2.5E-25 T 23-10-2018 A3L04_07355 b5b8b0d32a2bb514cab9974f08fec263 300 Gene3D G3DSA:3.40.50.620 175 300 2.6E-20 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_07355 b5b8b0d32a2bb514cab9974f08fec263 300 SMART SM00981 73 167 2.7E-22 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L04_07355 b5b8b0d32a2bb514cab9974f08fec263 300 SUPERFAMILY SSF143437 1 175 4.19E-50 T 23-10-2018 A3L04_07355 b5b8b0d32a2bb514cab9974f08fec263 300 Gene3D G3DSA:3.30.2300.10 84 165 2.5E-32 T 23-10-2018 A3L04_07355 b5b8b0d32a2bb514cab9974f08fec263 300 Pfam PF02926 THUMP domain 28 166 1.7E-27 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L04_07355 b5b8b0d32a2bb514cab9974f08fec263 300 Gene3D G3DSA:3.30.70.1510 1 83 9.3E-31 T 23-10-2018 A3L04_07355 b5b8b0d32a2bb514cab9974f08fec263 300 SUPERFAMILY SSF52402 178 299 9.63E-16 T 23-10-2018 A3L04_05325 4126ed91c7d9169d1b2e23a9f9ea4095 225 SUPERFAMILY SSF56281 3 214 6.63E-48 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_05325 4126ed91c7d9169d1b2e23a9f9ea4095 225 Pfam PF00753 Metallo-beta-lactamase superfamily 19 206 1.2E-28 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_05325 4126ed91c7d9169d1b2e23a9f9ea4095 225 Gene3D G3DSA:3.60.15.10 1 219 5.7E-49 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_05325 4126ed91c7d9169d1b2e23a9f9ea4095 225 SMART SM00849 19 206 3.2E-42 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_02640 9947f123fa42cc0a18d87a4689b90a53 60 Pfam PF01954 Protein of unknown function DUF104 1 56 1.4E-20 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 A3L04_02640 9947f123fa42cc0a18d87a4689b90a53 60 SUPERFAMILY SSF141694 1 58 2.25E-16 T 23-10-2018 A3L04_02640 9947f123fa42cc0a18d87a4689b90a53 60 Gene3D G3DSA:4.10.1150.10 1 60 9.4E-18 T 23-10-2018 IPR024069 AF2212-like domain superfamily A3L04_02810 6f5205b9fca639646196fb3639a9221b 141 Gene3D G3DSA:2.40.50.140 69 140 1.3E-22 T 23-10-2018 A3L04_02810 6f5205b9fca639646196fb3639a9221b 141 Pfam PF01957 NfeD-like C-terminal, partner-binding 7 137 5.1E-20 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain A3L04_02810 6f5205b9fca639646196fb3639a9221b 141 SUPERFAMILY SSF141322 70 136 2.48E-22 T 23-10-2018 A3L04_00020 d77203490f43679f57699d7cc02849fe 493 PRINTS PR00131 Glycosyl hydrolase family 1 signature 449 461 7.1E-18 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L04_00020 d77203490f43679f57699d7cc02849fe 493 PRINTS PR00131 Glycosyl hydrolase family 1 signature 425 442 7.1E-18 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L04_00020 d77203490f43679f57699d7cc02849fe 493 PRINTS PR00131 Glycosyl hydrolase family 1 signature 404 415 7.1E-18 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L04_00020 d77203490f43679f57699d7cc02849fe 493 PRINTS PR00131 Glycosyl hydrolase family 1 signature 315 329 7.1E-18 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L04_00020 d77203490f43679f57699d7cc02849fe 493 PRINTS PR00131 Glycosyl hydrolase family 1 signature 392 400 7.1E-18 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L04_00020 d77203490f43679f57699d7cc02849fe 493 Pfam PF00232 Glycosyl hydrolase family 1 30 74 1.7E-6 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L04_00020 d77203490f43679f57699d7cc02849fe 493 Pfam PF00232 Glycosyl hydrolase family 1 108 480 3.2E-57 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L04_00020 d77203490f43679f57699d7cc02849fe 493 SUPERFAMILY SSF51445 9 485 3.73E-118 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L04_00020 d77203490f43679f57699d7cc02849fe 493 Gene3D G3DSA:3.20.20.80 2 492 2.6E-138 T 23-10-2018 A3L04_00020 d77203490f43679f57699d7cc02849fe 493 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 392 400 - T 23-10-2018 IPR018120 Glycoside hydrolase family 1, active site A3L04_01395 6050f134c6050bec50d82659f3d53b9d 357 SMART SM00981 60 149 1.6E-20 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L04_01395 6050f134c6050bec50d82659f3d53b9d 357 SUPERFAMILY SSF75217 184 341 3.47E-23 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L04_01395 6050f134c6050bec50d82659f3d53b9d 357 Gene3D G3DSA:3.30.2130.30 1 149 2.9E-18 T 23-10-2018 A3L04_01395 6050f134c6050bec50d82659f3d53b9d 357 SUPERFAMILY SSF143437 3 147 4.19E-25 T 23-10-2018 A3L04_01395 6050f134c6050bec50d82659f3d53b9d 357 Pfam PF02926 THUMP domain 27 148 1.1E-27 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L04_01395 6050f134c6050bec50d82659f3d53b9d 357 Pfam PF14419 AF2226-like SPOUT RNA Methylase fused to THUMP 172 345 1.8E-82 T 23-10-2018 IPR025849 AF2226-like SPOUT RNA methylase fused to THUMP A3L04_07710 4c87c1202bf832024e524bd58a05e6e9 648 SUPERFAMILY SSF54814 96 141 4.58E-5 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L04_07710 4c87c1202bf832024e524bd58a05e6e9 648 Gene3D G3DSA:3.30.300.20 72 142 3.2E-65 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L04_07710 4c87c1202bf832024e524bd58a05e6e9 648 Pfam PF17214 KH domain 9 76 3.1E-27 T 23-10-2018 IPR033769 KH domain, archaeal A3L04_07710 4c87c1202bf832024e524bd58a05e6e9 648 Gene3D G3DSA:3.30.300.230 18 176 3.2E-65 T 23-10-2018 A3L04_07710 4c87c1202bf832024e524bd58a05e6e9 648 Pfam PF16661 Metallo-beta-lactamase superfamily domain 203 351 6.3E-10 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_07710 4c87c1202bf832024e524bd58a05e6e9 648 SMART SM00322 35 91 59.0 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L04_07710 4c87c1202bf832024e524bd58a05e6e9 648 SMART SM00322 102 169 9.9E-4 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L04_07710 4c87c1202bf832024e524bd58a05e6e9 648 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 576 639 3.8E-19 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A3L04_07710 4c87c1202bf832024e524bd58a05e6e9 648 Gene3D G3DSA:3.40.50.10890 401 588 1.8E-174 T 23-10-2018 A3L04_07710 4c87c1202bf832024e524bd58a05e6e9 648 SMART SM00849 198 428 1.6E-25 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_07710 4c87c1202bf832024e524bd58a05e6e9 648 Gene3D G3DSA:3.60.15.10 191 628 1.8E-174 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_07710 4c87c1202bf832024e524bd58a05e6e9 648 Pfam PF10996 Beta-Casp domain 433 556 5.8E-25 T 23-10-2018 IPR022712 Beta-Casp domain A3L04_07710 4c87c1202bf832024e524bd58a05e6e9 648 TIGRFAM TIGR03675 arCOG00543: arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein 13 647 9.5E-303 T 23-10-2018 IPR019975 KH-domain/beta-lactamase-domain protein, archaea A3L04_07710 4c87c1202bf832024e524bd58a05e6e9 648 SMART SM01027 433 557 9.8E-56 T 23-10-2018 IPR022712 Beta-Casp domain A3L04_07710 4c87c1202bf832024e524bd58a05e6e9 648 SUPERFAMILY SSF56281 183 647 4.88E-137 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_06115 71911e13b1ac358c6656ed47541c72f3 476 SUPERFAMILY SSF51621 5 341 1.15E-95 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A3L04_06115 71911e13b1ac358c6656ed47541c72f3 476 PRINTS PR01050 Pyruvate kinase family signature 188 202 1.8E-62 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L04_06115 71911e13b1ac358c6656ed47541c72f3 476 PRINTS PR01050 Pyruvate kinase family signature 219 245 1.8E-62 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L04_06115 71911e13b1ac358c6656ed47541c72f3 476 PRINTS PR01050 Pyruvate kinase family signature 63 79 1.8E-62 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L04_06115 71911e13b1ac358c6656ed47541c72f3 476 PRINTS PR01050 Pyruvate kinase family signature 246 270 1.8E-62 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L04_06115 71911e13b1ac358c6656ed47541c72f3 476 PRINTS PR01050 Pyruvate kinase family signature 271 295 1.8E-62 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L04_06115 71911e13b1ac358c6656ed47541c72f3 476 PRINTS PR01050 Pyruvate kinase family signature 296 314 1.8E-62 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L04_06115 71911e13b1ac358c6656ed47541c72f3 476 PRINTS PR01050 Pyruvate kinase family signature 315 331 1.8E-62 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L04_06115 71911e13b1ac358c6656ed47541c72f3 476 Gene3D G3DSA:3.20.20.60 7 337 3.8E-170 T 23-10-2018 A3L04_06115 71911e13b1ac358c6656ed47541c72f3 476 Gene3D G3DSA:3.40.1380.20 338 471 3.8E-170 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L04_06115 71911e13b1ac358c6656ed47541c72f3 476 Pfam PF02887 Pyruvate kinase, alpha/beta domain 364 472 2.1E-20 T 23-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L04_06115 71911e13b1ac358c6656ed47541c72f3 476 SUPERFAMILY SSF52935 325 475 1.31E-30 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L04_06115 71911e13b1ac358c6656ed47541c72f3 476 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 475 2.4E-182 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L04_06115 71911e13b1ac358c6656ed47541c72f3 476 ProSitePatterns PS00110 Pyruvate kinase active site signature. 217 229 - T 23-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L04_06115 71911e13b1ac358c6656ed47541c72f3 476 Gene3D G3DSA:2.40.33.10 74 170 3.8E-170 T 23-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L04_06115 71911e13b1ac358c6656ed47541c72f3 476 Pfam PF00224 Pyruvate kinase, barrel domain 6 340 1.8E-121 T 23-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L04_06115 71911e13b1ac358c6656ed47541c72f3 476 SUPERFAMILY SSF50800 75 168 1.22E-26 T 23-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily A3L04_08850 3e65b340c13718f77b692af20dbea5d3 607 SUPERFAMILY SSF48310 211 606 1.96E-145 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L04_08850 3e65b340c13718f77b692af20dbea5d3 607 Gene3D G3DSA:1.10.599.10 240 603 1.1E-155 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A3L04_08850 3e65b340c13718f77b692af20dbea5d3 607 Gene3D G3DSA:3.60.9.10 1 211 5.9E-99 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L04_08850 3e65b340c13718f77b692af20dbea5d3 607 Gene3D G3DSA:1.10.569.10 242 429 1.1E-155 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L04_08850 3e65b340c13718f77b692af20dbea5d3 607 SMART SM00790 4 207 3.0E-135 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L04_08850 3e65b340c13718f77b692af20dbea5d3 607 SUPERFAMILY SSF56228 1 209 1.57E-82 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L04_08850 3e65b340c13718f77b692af20dbea5d3 607 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 205 2.2E-86 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L04_08850 3e65b340c13718f77b692af20dbea5d3 607 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 220 603 3.1E-144 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L04_04200 77f13dbb247a69bf2211475ea1663e69 387 SUPERFAMILY SSF52540 83 322 4.46E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_04200 77f13dbb247a69bf2211475ea1663e69 387 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 82 189 2.0E-15 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L04_04200 77f13dbb247a69bf2211475ea1663e69 387 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 132 147 3.0E-27 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_04200 77f13dbb247a69bf2211475ea1663e69 387 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 84 104 3.0E-27 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_04200 77f13dbb247a69bf2211475ea1663e69 387 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 105 123 3.0E-27 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_04200 77f13dbb247a69bf2211475ea1663e69 387 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 149 167 3.0E-27 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_04200 77f13dbb247a69bf2211475ea1663e69 387 Gene3D G3DSA:3.10.20.30 311 387 2.6E-29 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L04_04200 77f13dbb247a69bf2211475ea1663e69 387 SUPERFAMILY SSF81271 308 385 5.49E-19 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A3L04_04200 77f13dbb247a69bf2211475ea1663e69 387 Pfam PF02824 TGS domain 314 385 8.6E-24 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A3L04_04200 77f13dbb247a69bf2211475ea1663e69 387 Pfam PF16897 C-terminal region of MMR_HSR1 domain 205 309 1.9E-18 T 23-10-2018 IPR031662 GTP binding protein, second domain A3L04_04200 77f13dbb247a69bf2211475ea1663e69 387 Pfam PF01926 50S ribosome-binding GTPase 83 183 3.4E-21 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_01325 676283e45317c679af7fe4b7197d138f 166 Gene3D G3DSA:2.30.130.10 95 166 1.7E-22 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L04_01325 676283e45317c679af7fe4b7197d138f 166 Gene3D G3DSA:3.10.450.220 1 94 1.1E-53 T 23-10-2018 A3L04_01325 676283e45317c679af7fe4b7197d138f 166 Pfam PF03657 Uncharacterised protein family (UPF0113) 6 166 2.0E-15 T 23-10-2018 IPR005155 Ribosome biogenesis factor NIP7-like Reactome: R-HSA-6791226 A3L04_07540 cca55f783f3300fe034e76a33be3a640 401 SUPERFAMILY SSF52507 18 217 1.7E-47 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A3L04_07540 cca55f783f3300fe034e76a33be3a640 401 Gene3D G3DSA:3.40.50.10300 189 401 7.3E-69 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A3L04_07540 cca55f783f3300fe034e76a33be3a640 401 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 193 373 1.4E-57 T 23-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A3L04_07540 cca55f783f3300fe034e76a33be3a640 401 Pfam PF02441 Flavoprotein 19 188 2.2E-41 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A3L04_07540 cca55f783f3300fe034e76a33be3a640 401 Gene3D G3DSA:3.40.50.1950 15 187 3.5E-48 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A3L04_07540 cca55f783f3300fe034e76a33be3a640 401 SUPERFAMILY SSF102645 180 400 1.2E-64 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A3L04_07540 cca55f783f3300fe034e76a33be3a640 401 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 18 397 3.8E-129 T 23-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 A3L04_03370 073f8677330722714f9f0b36a71a04dd 258 Gene3D G3DSA:2.40.50.140 91 157 5.5E-75 T 23-10-2018 A3L04_03370 073f8677330722714f9f0b36a71a04dd 258 SUPERFAMILY SSF75217 4 256 1.57E-47 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L04_03370 073f8677330722714f9f0b36a71a04dd 258 SUPERFAMILY SSF50249 90 157 7.71E-13 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_03370 073f8677330722714f9f0b36a71a04dd 258 Gene3D G3DSA:3.40.1280.10 5 254 5.5E-75 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L04_03370 073f8677330722714f9f0b36a71a04dd 258 Pfam PF02598 Putative RNA methyltransferase 5 251 1.4E-52 T 23-10-2018 IPR003750 Putative RNA methyltransferase A3L04_01720 1b37bce9a60857c8367e351189f8118d 444 Pfam PF00271 Helicase conserved C-terminal domain 306 404 3.8E-11 T 23-10-2018 IPR001650 Helicase, C-terminal A3L04_01720 1b37bce9a60857c8367e351189f8118d 444 Pfam PF04851 Type III restriction enzyme, res subunit 92 231 1.6E-19 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A3L04_01720 1b37bce9a60857c8367e351189f8118d 444 SUPERFAMILY SSF52540 25 252 1.41E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01720 1b37bce9a60857c8367e351189f8118d 444 SUPERFAMILY SSF52540 113 434 1.03E-26 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01720 1b37bce9a60857c8367e351189f8118d 444 Gene3D G3DSA:3.40.50.300 272 443 2.2E-34 T 23-10-2018 A3L04_01720 1b37bce9a60857c8367e351189f8118d 444 Gene3D G3DSA:3.40.50.300 85 261 7.5E-36 T 23-10-2018 A3L04_01720 1b37bce9a60857c8367e351189f8118d 444 SMART SM00487 91 262 9.6E-27 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L04_01720 1b37bce9a60857c8367e351189f8118d 444 SMART SM00490 328 406 9.0E-14 T 23-10-2018 IPR001650 Helicase, C-terminal A3L04_02375 e43ab53b3c013a7a9c2c98718565f987 188 SUPERFAMILY SSF50249 80 179 5.89E-26 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_02375 e43ab53b3c013a7a9c2c98718565f987 188 Pfam PF00575 S1 RNA binding domain 79 154 1.4E-15 T 23-10-2018 IPR003029 S1 domain GO:0003676 A3L04_02375 e43ab53b3c013a7a9c2c98718565f987 188 SUPERFAMILY SSF88798 1 77 5.36E-21 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 A3L04_02375 e43ab53b3c013a7a9c2c98718565f987 188 Gene3D G3DSA:2.40.50.140 82 188 2.5E-33 T 23-10-2018 A3L04_02375 e43ab53b3c013a7a9c2c98718565f987 188 TIGRFAM TIGR00448 rpoE: DNA-directed RNA polymerase 1 179 1.0E-65 T 23-10-2018 IPR004519 DNA-directed RNA polymerase, subunit E/RPC8 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 A3L04_02375 e43ab53b3c013a7a9c2c98718565f987 188 Pfam PF03876 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 8 77 2.5E-20 T 23-10-2018 IPR005576 RNA polymerase Rpb7, N-terminal GO:0003899|GO:0006351 A3L04_02375 e43ab53b3c013a7a9c2c98718565f987 188 SMART SM00316 80 166 8.9E-19 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L04_02375 e43ab53b3c013a7a9c2c98718565f987 188 Gene3D G3DSA:3.30.1490.120 1 80 1.5E-31 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 A3L04_01170 3fc820257bd49fb538068a68ff4cfcc8 224 SMART SM00382 19 203 6.4E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_01170 3fc820257bd49fb538068a68ff4cfcc8 224 SUPERFAMILY SSF52540 1 196 7.59E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01170 3fc820257bd49fb538068a68ff4cfcc8 224 Gene3D G3DSA:3.40.50.300 1 194 5.6E-20 T 23-10-2018 A3L04_01170 3fc820257bd49fb538068a68ff4cfcc8 224 Pfam PF01637 ATPase domain predominantly from Archaea 2 200 1.8E-49 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_04550 e320bc6d98360965c93f63272a098737 503 Gene3D G3DSA:3.40.1030.10 152 412 3.7E-101 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L04_04550 e320bc6d98360965c93f63272a098737 503 Hamap MF_02132 AMP phosphorylase. 1 503 47.176 T 23-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 A3L04_04550 e320bc6d98360965c93f63272a098737 503 Gene3D G3DSA:3.90.1170.30 413 493 3.8E-30 T 23-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L04_04550 e320bc6d98360965c93f63272a098737 503 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 424 485 1.4E-16 T 23-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L04_04550 e320bc6d98360965c93f63272a098737 503 SUPERFAMILY SSF50692 5 60 1.7E-6 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L04_04550 e320bc6d98360965c93f63272a098737 503 SUPERFAMILY SSF52418 155 404 2.49E-70 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L04_04550 e320bc6d98360965c93f63272a098737 503 TIGRFAM TIGR03327 AMP_phos: AMP phosphorylase 3 499 3.0E-244 T 23-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 A3L04_04550 e320bc6d98360965c93f63272a098737 503 Gene3D G3DSA:2.40.40.20 1 83 8.9E-36 T 23-10-2018 A3L04_04550 e320bc6d98360965c93f63272a098737 503 Pfam PF00591 Glycosyl transferase family, a/b domain 158 387 2.2E-15 T 23-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L04_04550 e320bc6d98360965c93f63272a098737 503 SMART SM00941 424 491 8.1E-26 T 23-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L04_04550 e320bc6d98360965c93f63272a098737 503 Gene3D G3DSA:1.20.970.10 84 151 7.2E-24 T 23-10-2018 A3L04_04550 e320bc6d98360965c93f63272a098737 503 SUPERFAMILY SSF47648 86 153 3.27E-16 T 23-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L04_04550 e320bc6d98360965c93f63272a098737 503 PIRSF PIRSF000478 84 500 3.0E-126 T 23-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L04_04550 e320bc6d98360965c93f63272a098737 503 SUPERFAMILY SSF54680 412 495 3.27E-19 T 23-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L04_04550 e320bc6d98360965c93f63272a098737 503 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 193 208 - T 23-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L04_04550 e320bc6d98360965c93f63272a098737 503 Pfam PF02885 Glycosyl transferase family, helical bundle domain 89 150 7.3E-14 T 23-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L04_04550 e320bc6d98360965c93f63272a098737 503 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 4 494 7.6E-237 T 23-10-2018 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 A3L04_06310 73a6218895152a42fba7c599e58d2646 878 SUPERFAMILY SSF75712 394 491 1.83E-17 T 23-10-2018 A3L04_06310 73a6218895152a42fba7c599e58d2646 878 Gene3D G3DSA:3.40.50.300 668 878 6.1E-43 T 23-10-2018 A3L04_06310 73a6218895152a42fba7c599e58d2646 878 Gene3D G3DSA:3.40.50.300 1 242 4.9E-46 T 23-10-2018 A3L04_06310 73a6218895152a42fba7c599e58d2646 878 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 45 1.6E-10 T 23-10-2018 IPR003395 RecF/RecN/SMC, N-terminal A3L04_06310 73a6218895152a42fba7c599e58d2646 878 Hamap MF_00449 DNA double-strand break repair Rad50 ATPase [rad50]. 1 876 13.541 T 23-10-2018 IPR022982 DNA double-strand break repair Rad50 ATPase, archaeal type A3L04_06310 73a6218895152a42fba7c599e58d2646 878 SUPERFAMILY SSF52540 1 866 2.27E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_06310 73a6218895152a42fba7c599e58d2646 878 Pfam PF04423 Rad50 zinc hook motif 425 468 9.0E-14 T 23-10-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A3L04_06310 73a6218895152a42fba7c599e58d2646 878 Gene3D G3DSA:1.10.287.510 392 502 1.3E-27 T 23-10-2018 A3L04_06310 73a6218895152a42fba7c599e58d2646 878 SUPERFAMILY SSF52540 1 246 1.12E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_07845 bbe0f73cad5586bcecc7fed185c119ef 629 Pfam PF00750 tRNA synthetases class I (R) 376 493 7.3E-10 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 A3L04_07845 bbe0f73cad5586bcecc7fed185c119ef 629 Pfam PF00750 tRNA synthetases class I (R) 100 339 1.3E-27 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 A3L04_07845 bbe0f73cad5586bcecc7fed185c119ef 629 SMART SM00836 507 629 4.6E-47 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A3L04_07845 bbe0f73cad5586bcecc7fed185c119ef 629 SUPERFAMILY SSF47323 503 629 5.3E-35 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_07845 bbe0f73cad5586bcecc7fed185c119ef 629 Gene3D G3DSA:1.10.730.10 511 629 6.1E-40 T 23-10-2018 A3L04_07845 bbe0f73cad5586bcecc7fed185c119ef 629 PRINTS PR01038 Arginyl-tRNA synthetase signature 120 135 1.5E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L04_07845 bbe0f73cad5586bcecc7fed185c119ef 629 PRINTS PR01038 Arginyl-tRNA synthetase signature 321 342 1.5E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L04_07845 bbe0f73cad5586bcecc7fed185c119ef 629 PRINTS PR01038 Arginyl-tRNA synthetase signature 135 151 1.5E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L04_07845 bbe0f73cad5586bcecc7fed185c119ef 629 PRINTS PR01038 Arginyl-tRNA synthetase signature 159 172 1.5E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L04_07845 bbe0f73cad5586bcecc7fed185c119ef 629 Gene3D G3DSA:3.40.50.620 117 510 4.1E-168 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_07845 bbe0f73cad5586bcecc7fed185c119ef 629 SUPERFAMILY SSF52374 115 500 1.72E-83 T 23-10-2018 A3L04_07845 bbe0f73cad5586bcecc7fed185c119ef 629 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 7 356 1.4E-78 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L04_07845 bbe0f73cad5586bcecc7fed185c119ef 629 Hamap MF_00123 Arginine--tRNA ligase [argS]. 7 629 28.236 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L04_07845 bbe0f73cad5586bcecc7fed185c119ef 629 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 130 139 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_07845 bbe0f73cad5586bcecc7fed185c119ef 629 Pfam PF05746 DALR anticodon binding domain 507 629 6.2E-36 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A3L04_07845 bbe0f73cad5586bcecc7fed185c119ef 629 SMART SM01016 3 90 2.9E-20 T 23-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L04_07845 bbe0f73cad5586bcecc7fed185c119ef 629 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 10 90 6.7E-16 T 23-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L04_07845 bbe0f73cad5586bcecc7fed185c119ef 629 SUPERFAMILY SSF55190 12 111 6.67E-18 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A3L04_07845 bbe0f73cad5586bcecc7fed185c119ef 629 Gene3D G3DSA:3.30.1360.70 1 116 4.6E-34 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A3L04_09320 7bd2b304cecc28fdbd386070e4c57bf7 146 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 102 119 - T 23-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A3L04_09320 7bd2b304cecc28fdbd386070e4c57bf7 146 Pfam PF00364 Biotin-requiring enzyme 79 145 1.0E-23 T 23-10-2018 IPR000089 Biotin/lipoyl attachment A3L04_09320 7bd2b304cecc28fdbd386070e4c57bf7 146 SUPERFAMILY SSF51230 74 145 6.94E-26 T 23-10-2018 IPR011053 Single hybrid motif A3L04_09320 7bd2b304cecc28fdbd386070e4c57bf7 146 Gene3D G3DSA:2.40.50.100 73 146 8.8E-30 T 23-10-2018 A3L04_06760 072ebd0ae4e911c09fd2933bc759b955 625 SUPERFAMILY SSF52954 503 606 1.66E-31 T 23-10-2018 A3L04_06760 072ebd0ae4e911c09fd2933bc759b955 625 Gene3D G3DSA:3.30.930.10 202 493 2.7E-63 T 23-10-2018 A3L04_06760 072ebd0ae4e911c09fd2933bc759b955 625 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 288 491 9.2E-21 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_06760 072ebd0ae4e911c09fd2933bc759b955 625 Pfam PF03129 Anticodon binding domain 512 601 7.2E-26 T 23-10-2018 IPR004154 Anticodon-binding A3L04_06760 072ebd0ae4e911c09fd2933bc759b955 625 PRINTS PR01047 Threonyl-tRNA synthetase signature 327 350 7.6E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L04_06760 072ebd0ae4e911c09fd2933bc759b955 625 PRINTS PR01047 Threonyl-tRNA synthetase signature 470 483 7.6E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L04_06760 072ebd0ae4e911c09fd2933bc759b955 625 PRINTS PR01047 Threonyl-tRNA synthetase signature 293 321 7.6E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L04_06760 072ebd0ae4e911c09fd2933bc759b955 625 PRINTS PR01047 Threonyl-tRNA synthetase signature 427 455 7.6E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L04_06760 072ebd0ae4e911c09fd2933bc759b955 625 PRINTS PR01047 Threonyl-tRNA synthetase signature 505 517 7.6E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L04_06760 072ebd0ae4e911c09fd2933bc759b955 625 ProDom PD016189 SYNTHETASE LIGASE THREONYL-TRNA AMINOACYL-TRNA NUCLEOTIDE-BINDING BIOSYNTHESIS ATP-BINDING ZINC METAL-BINDING THRRS 1 139 8.0E-48 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 A3L04_06760 072ebd0ae4e911c09fd2933bc759b955 625 Pfam PF08915 Archaea-specific editing domain of threonyl-tRNA synthetase 2 139 6.5E-56 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 A3L04_06760 072ebd0ae4e911c09fd2933bc759b955 625 SUPERFAMILY SSF55681 206 488 3.45E-58 T 23-10-2018 A3L04_06760 072ebd0ae4e911c09fd2933bc759b955 625 Gene3D G3DSA:3.40.50.800 503 606 1.0E-32 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A3L04_06760 072ebd0ae4e911c09fd2933bc759b955 625 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 35 601 29.515 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L04_06760 072ebd0ae4e911c09fd2933bc759b955 625 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 25 602 1.2E-176 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L04_06760 072ebd0ae4e911c09fd2933bc759b955 625 Gene3D G3DSA:3.50.80.10 1 139 1.7E-57 T 23-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily A3L04_05280 a3d9236862597d96b4182087b1a0b533 267 Pfam PF13412 Winged helix-turn-helix DNA-binding 209 251 5.9E-8 T 23-10-2018 A3L04_05280 a3d9236862597d96b4182087b1a0b533 267 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 204 220 2.9E-5 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_05280 a3d9236862597d96b4182087b1a0b533 267 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 220 231 2.9E-5 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_05280 a3d9236862597d96b4182087b1a0b533 267 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 231 250 2.9E-5 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_05280 a3d9236862597d96b4182087b1a0b533 267 SUPERFAMILY SSF46785 191 257 2.31E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_05280 a3d9236862597d96b4182087b1a0b533 267 Gene3D G3DSA:1.10.10.10 182 258 3.6E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_02385 a4039339d5d15738ac5b94d5e9550127 281 Pfam PF01261 Xylose isomerase-like TIM barrel 28 239 4.7E-21 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A3L04_02385 a4039339d5d15738ac5b94d5e9550127 281 SUPERFAMILY SSF51658 7 278 9.17E-62 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily A3L04_02385 a4039339d5d15738ac5b94d5e9550127 281 Gene3D G3DSA:3.20.20.150 13 280 2.3E-43 T 23-10-2018 A3L04_02385 a4039339d5d15738ac5b94d5e9550127 281 SMART SM00518 4 276 7.2E-92 T 23-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A3L04_04800 4f39fc777371a90484fe72ac15f7c240 1117 Pfam PF04567 RNA polymerase Rpb2, domain 5 601 633 7.2E-10 T 23-10-2018 IPR007647 RNA polymerase Rpb2, domain 5 GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04800 4f39fc777371a90484fe72ac15f7c240 1117 Gene3D G3DSA:2.40.270.10 649 1006 1.7E-145 T 23-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04800 4f39fc777371a90484fe72ac15f7c240 1117 Pfam PF04563 RNA polymerase beta subunit 26 379 2.3E-53 T 23-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04800 4f39fc777371a90484fe72ac15f7c240 1117 Gene3D G3DSA:3.90.1800.10 1007 1115 5.2E-42 T 23-10-2018 A3L04_04800 4f39fc777371a90484fe72ac15f7c240 1117 Pfam PF04566 RNA polymerase Rpb2, domain 4 519 580 5.7E-21 T 23-10-2018 IPR007646 RNA polymerase Rpb2, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04800 4f39fc777371a90484fe72ac15f7c240 1117 Gene3D G3DSA:2.40.50.150 679 869 1.7E-145 T 23-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04800 4f39fc777371a90484fe72ac15f7c240 1117 TIGRFAM TIGR03670 rpoB_arch: DNA-directed RNA polymerase subunit B 519 1116 0.0 T 23-10-2018 IPR019969 DNA-directed RNA polymerase subunit B (Rpo2) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04800 4f39fc777371a90484fe72ac15f7c240 1117 Gene3D G3DSA:3.90.1100.10 19 172 6.0E-13 T 23-10-2018 A3L04_04800 4f39fc777371a90484fe72ac15f7c240 1117 Gene3D G3DSA:3.90.1100.10 332 506 3.6E-50 T 23-10-2018 A3L04_04800 4f39fc777371a90484fe72ac15f7c240 1117 Gene3D G3DSA:3.90.1110.10 174 331 7.5E-60 T 23-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04800 4f39fc777371a90484fe72ac15f7c240 1117 Pfam PF00562 RNA polymerase Rpb2, domain 6 649 1020 7.2E-131 T 23-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04800 4f39fc777371a90484fe72ac15f7c240 1117 SUPERFAMILY SSF64484 10 1114 0.0 T 23-10-2018 A3L04_04800 4f39fc777371a90484fe72ac15f7c240 1117 ProSitePatterns PS01166 RNA polymerases beta chain signature. 873 885 - T 23-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04800 4f39fc777371a90484fe72ac15f7c240 1117 Pfam PF04565 RNA polymerase Rpb2, domain 3 422 486 2.6E-29 T 23-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04800 4f39fc777371a90484fe72ac15f7c240 1117 Pfam PF04560 RNA polymerase Rpb2, domain 7 1022 1112 1.9E-31 T 23-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04800 4f39fc777371a90484fe72ac15f7c240 1117 Pfam PF04561 RNA polymerase Rpb2, domain 2 173 346 1.4E-38 T 23-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_09180 140c465bd2ff445f3fca94c636eb7189 438 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 146 283 4.8E-57 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L04_09180 140c465bd2ff445f3fca94c636eb7189 438 SUPERFAMILY SSF52210 290 436 3.92E-39 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L04_09180 140c465bd2ff445f3fca94c636eb7189 438 SUPERFAMILY SSF51735 2 131 3.74E-21 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_09180 140c465bd2ff445f3fca94c636eb7189 438 SUPERFAMILY SSF52210 128 283 4.71E-42 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L04_09180 140c465bd2ff445f3fca94c636eb7189 438 Gene3D G3DSA:3.40.50.261 287 438 5.1E-53 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L04_09180 140c465bd2ff445f3fca94c636eb7189 438 Gene3D G3DSA:3.40.50.261 135 286 7.5E-61 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L04_09180 140c465bd2ff445f3fca94c636eb7189 438 Gene3D G3DSA:3.40.50.720 1 125 2.2E-28 T 23-10-2018 A3L04_09180 140c465bd2ff445f3fca94c636eb7189 438 Pfam PF13380 CoA binding domain 8 129 1.2E-16 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L04_09180 140c465bd2ff445f3fca94c636eb7189 438 SMART SM00881 4 98 3.1E-17 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L04_03830 f7415cd21172e2a866f59c290cf3e143 306 Pfam PF02779 Transketolase, pyrimidine binding domain 5 163 1.9E-40 T 23-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A3L04_03830 f7415cd21172e2a866f59c290cf3e143 306 Gene3D G3DSA:3.40.50.970 2 175 2.2E-64 T 23-10-2018 A3L04_03830 f7415cd21172e2a866f59c290cf3e143 306 Gene3D G3DSA:3.40.50.920 178 306 1.2E-37 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L04_03830 f7415cd21172e2a866f59c290cf3e143 306 SMART SM00861 3 168 1.6E-57 T 23-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A3L04_03830 f7415cd21172e2a866f59c290cf3e143 306 Pfam PF02780 Transketolase, C-terminal domain 178 298 3.0E-33 T 23-10-2018 IPR033248 Transketolase, C-terminal domain A3L04_03830 f7415cd21172e2a866f59c290cf3e143 306 SUPERFAMILY SSF52922 174 305 1.22E-35 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L04_03830 f7415cd21172e2a866f59c290cf3e143 306 SUPERFAMILY SSF52518 4 169 3.43E-56 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L04_05805 6b572eed6baa8b327439375fa3c11eb4 355 Gene3D G3DSA:3.40.718.10 1 348 1.8E-143 T 23-10-2018 A3L04_05805 6b572eed6baa8b327439375fa3c11eb4 355 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 237 256 - T 23-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A3L04_05805 6b572eed6baa8b327439375fa3c11eb4 355 SMART SM01329 3 341 8.6E-191 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A3L04_05805 6b572eed6baa8b327439375fa3c11eb4 355 SUPERFAMILY SSF53659 2 345 3.26E-127 T 23-10-2018 A3L04_05805 6b572eed6baa8b327439375fa3c11eb4 355 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 3 341 3.5E-110 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A3L04_03335 2682fc4b5003df31d42d45bee3c2e190 203 Pfam PF07998 Peptidase family M54 3 194 1.3E-94 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 A3L04_03335 2682fc4b5003df31d42d45bee3c2e190 203 PIRSF PIRSF005785 2 203 2.2E-64 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 A3L04_03335 2682fc4b5003df31d42d45bee3c2e190 203 Gene3D G3DSA:3.40.390.10 107 199 3.7E-22 T 23-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 A3L04_03335 2682fc4b5003df31d42d45bee3c2e190 203 SUPERFAMILY SSF55486 144 193 1.55E-7 T 23-10-2018 A3L04_00465 f5227c730e5657f089e9754f7b1bdac0 211 Gene3D G3DSA:3.40.50.300 1 206 1.7E-43 T 23-10-2018 A3L04_00465 f5227c730e5657f089e9754f7b1bdac0 211 Pfam PF00005 ABC transporter 18 154 2.6E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_00465 f5227c730e5657f089e9754f7b1bdac0 211 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_00465 f5227c730e5657f089e9754f7b1bdac0 211 SMART SM00382 27 209 0.0044 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_00465 f5227c730e5657f089e9754f7b1bdac0 211 SUPERFAMILY SSF52540 2 184 4.17E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_07885 e725a6eb385bca8991bf303348edc314 286 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 6 281 6.5E-80 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A3L04_07885 e725a6eb385bca8991bf303348edc314 286 Gene3D G3DSA:1.20.1510.10 5 200 1.2E-61 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A3L04_07885 e725a6eb385bca8991bf303348edc314 286 SUPERFAMILY SSF161111 2 202 3.27E-57 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A3L04_07885 e725a6eb385bca8991bf303348edc314 286 Pfam PF01545 Cation efflux family 9 200 9.8E-46 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A3L04_07885 e725a6eb385bca8991bf303348edc314 286 Pfam PF16916 Dimerisation domain of Zinc Transporter 206 280 3.9E-25 T 23-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain A3L04_07885 e725a6eb385bca8991bf303348edc314 286 Gene3D G3DSA:3.30.70.1350 207 282 4.3E-24 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A3L04_07885 e725a6eb385bca8991bf303348edc314 286 SUPERFAMILY SSF160240 204 280 4.97E-23 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A3L04_09250 d3b8dc49b007c5c22b275bd65d1c0743 452 Gene3D G3DSA:3.30.70.1170 187 244 6.7E-29 T 23-10-2018 A3L04_09250 d3b8dc49b007c5c22b275bd65d1c0743 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 432 449 1.5E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_09250 d3b8dc49b007c5c22b275bd65d1c0743 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 236 250 1.5E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_09250 d3b8dc49b007c5c22b275bd65d1c0743 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 333 345 1.5E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_09250 d3b8dc49b007c5c22b275bd65d1c0743 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 383 399 1.5E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_09250 d3b8dc49b007c5c22b275bd65d1c0743 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 265 275 1.5E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_09250 d3b8dc49b007c5c22b275bd65d1c0743 452 Gene3D G3DSA:1.10.940.10 1 158 4.2E-61 T 23-10-2018 IPR035926 NusB-like superfamily A3L04_09250 d3b8dc49b007c5c22b275bd65d1c0743 452 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 190 449 2.8E-68 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L04_09250 d3b8dc49b007c5c22b275bd65d1c0743 452 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 159 249 2.1E-6 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L04_09250 d3b8dc49b007c5c22b275bd65d1c0743 452 Pfam PF01189 16S rRNA methyltransferase RsmB/F 254 447 5.6E-61 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L04_09250 d3b8dc49b007c5c22b275bd65d1c0743 452 Gene3D G3DSA:1.10.287.730 159 186 1.4E-17 T 23-10-2018 A3L04_09250 d3b8dc49b007c5c22b275bd65d1c0743 452 SUPERFAMILY SSF53335 150 449 3.56E-73 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_09250 d3b8dc49b007c5c22b275bd65d1c0743 452 Gene3D G3DSA:3.40.50.150 245 450 1.7E-73 T 23-10-2018 A3L04_10390 aef9cee8896f2da47b1fa0cfe5d70df3 208 Pfam PF01980 Uncharacterised protein family UPF0066 12 121 1.7E-29 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain A3L04_10390 aef9cee8896f2da47b1fa0cfe5d70df3 208 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 13 126 2.9E-35 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain A3L04_10390 aef9cee8896f2da47b1fa0cfe5d70df3 208 ProSitePatterns PS01318 TsaA-like domain signature. 69 80 - T 23-10-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site A3L04_10390 aef9cee8896f2da47b1fa0cfe5d70df3 208 Gene3D G3DSA:2.40.30.70 5 139 3.4E-31 T 23-10-2018 IPR036414 YaeB, N-terminal domain superfamily A3L04_10390 aef9cee8896f2da47b1fa0cfe5d70df3 208 SUPERFAMILY SSF118196 2 152 3.92E-40 T 23-10-2018 IPR036413 YaeB-like superfamily A3L04_07640 1974f4412be9942dbb2aaeff09a08cb9 229 Hamap MF_01419 Phosphoglycolate phosphatase. 3 226 32.245 T 23-10-2018 IPR006382 Phosphoglycolate phosphatase GO:0000287|GO:0008967|GO:0016311 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 A3L04_07640 1974f4412be9942dbb2aaeff09a08cb9 229 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 6 228 8.2E-77 T 23-10-2018 A3L04_07640 1974f4412be9942dbb2aaeff09a08cb9 229 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 3 219 2.5E-84 T 23-10-2018 A3L04_07640 1974f4412be9942dbb2aaeff09a08cb9 229 Gene3D G3DSA:3.90.1070.10 82 150 8.8E-81 T 23-10-2018 A3L04_07640 1974f4412be9942dbb2aaeff09a08cb9 229 SUPERFAMILY SSF56784 1 225 5.43E-44 T 23-10-2018 IPR036412 HAD-like superfamily A3L04_07640 1974f4412be9942dbb2aaeff09a08cb9 229 Gene3D G3DSA:3.40.50.1000 4 220 8.8E-81 T 23-10-2018 IPR023214 HAD superfamily A3L04_07640 1974f4412be9942dbb2aaeff09a08cb9 229 Pfam PF08282 haloacid dehalogenase-like hydrolase 115 220 1.5E-18 T 23-10-2018 A3L04_07640 1974f4412be9942dbb2aaeff09a08cb9 229 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 86 6.0E-11 T 23-10-2018 A3L04_00195 bd842787b0e3e3f5cfe9350bf5260da3 270 Pfam PF01336 OB-fold nucleic acid binding domain 45 113 9.0E-9 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L04_00195 bd842787b0e3e3f5cfe9350bf5260da3 270 Gene3D G3DSA:2.40.50.140 6 138 3.8E-14 T 23-10-2018 A3L04_00195 bd842787b0e3e3f5cfe9350bf5260da3 270 SUPERFAMILY SSF50249 11 131 3.26E-13 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 PRINTS PR00344 Bacterial sensor protein C-terminal signature 579 589 6.8E-15 T 23-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 PRINTS PR00344 Bacterial sensor protein C-terminal signature 595 613 6.8E-15 T 23-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 PRINTS PR00344 Bacterial sensor protein C-terminal signature 537 551 6.8E-15 T 23-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 PRINTS PR00344 Bacterial sensor protein C-terminal signature 619 632 6.8E-15 T 23-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 SMART SM00387 492 635 3.1E-33 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 Gene3D G3DSA:1.20.120.160 2 153 1.5E-35 T 23-10-2018 IPR036641 HPT domain superfamily GO:0000160 A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 495 632 8.2E-21 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 388 447 1.3E-16 T 23-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 Pfam PF01627 Hpt domain 6 106 2.5E-23 T 23-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 Gene3D G3DSA:2.40.50.180 658 719 1.2E-39 T 23-10-2018 A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 SMART SM01231 387 447 2.5E-20 T 23-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 Pfam PF07194 P2 response regulator binding domain 171 250 5.9E-19 T 23-10-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 Pfam PF07194 P2 response regulator binding domain 266 346 1.3E-19 T 23-10-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 SUPERFAMILY SSF55052 170 251 1.44E-18 T 23-10-2018 IPR035891 CheY-binding domain of CheA A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 SUPERFAMILY SSF50341 634 764 2.35E-34 T 23-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 Gene3D G3DSA:3.30.565.10 448 634 3.3E-64 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 SUPERFAMILY SSF55874 451 632 1.7E-46 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 Pfam PF01584 CheW-like domain 639 764 1.6E-25 T 23-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 Gene3D G3DSA:3.30.70.1110 262 347 1.6E-13 T 23-10-2018 IPR037052 Chemotaxis protein CheA, P2 response regulator-binding domain superfamily A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 Gene3D G3DSA:3.30.70.1110 169 252 2.8E-14 T 23-10-2018 IPR037052 Chemotaxis protein CheA, P2 response regulator-binding domain superfamily A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 SMART SM00073 4 108 2.2E-27 T 23-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 SUPERFAMILY SSF55052 262 346 1.39E-17 T 23-10-2018 IPR035891 CheY-binding domain of CheA A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 Gene3D G3DSA:1.10.287.560 387 447 1.4E-19 T 23-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 Gene3D G3DSA:2.30.30.40 635 760 1.2E-39 T 23-10-2018 A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 SMART SM00260 627 764 6.6E-44 T 23-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 SUPERFAMILY SSF47226 4 134 6.8E-30 T 23-10-2018 IPR036641 HPT domain superfamily GO:0000160 A3L04_02855 3c14d16d778bb53731bb60d03aafc4d6 770 SUPERFAMILY SSF47384 388 448 3.3E-16 T 23-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A3L04_08755 37503de404eb338096921bfe0d564ea4 451 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 132 1.0E-45 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08755 37503de404eb338096921bfe0d564ea4 451 Gene3D G3DSA:3.40.120.10 165 345 1.1E-54 T 23-10-2018 A3L04_08755 37503de404eb338096921bfe0d564ea4 451 SUPERFAMILY SSF53738 252 355 1.02E-23 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08755 37503de404eb338096921bfe0d564ea4 451 SUPERFAMILY SSF55957 348 446 3.01E-23 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08755 37503de404eb338096921bfe0d564ea4 451 Hamap MF_01554_A Phosphoglucosamine mutase [glmM]. 2 446 52.58 T 23-10-2018 IPR023666 Phosphoglucosamine mutase, archaeal GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08755 37503de404eb338096921bfe0d564ea4 451 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 254 357 2.0E-20 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08755 37503de404eb338096921bfe0d564ea4 451 SUPERFAMILY SSF53738 2 140 3.92E-46 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08755 37503de404eb338096921bfe0d564ea4 451 Gene3D G3DSA:3.40.120.10 247 330 1.1E-54 T 23-10-2018 A3L04_08755 37503de404eb338096921bfe0d564ea4 451 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 90 99 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08755 37503de404eb338096921bfe0d564ea4 451 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 374 441 1.4E-7 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08755 37503de404eb338096921bfe0d564ea4 451 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 442 3.1E-166 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08755 37503de404eb338096921bfe0d564ea4 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 89 103 5.3E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08755 37503de404eb338096921bfe0d564ea4 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 165 184 5.3E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08755 37503de404eb338096921bfe0d564ea4 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 226 241 5.3E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08755 37503de404eb338096921bfe0d564ea4 451 Gene3D G3DSA:3.30.310.50 360 449 3.2E-22 T 23-10-2018 A3L04_08755 37503de404eb338096921bfe0d564ea4 451 SUPERFAMILY SSF53738 150 249 1.69E-23 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08755 37503de404eb338096921bfe0d564ea4 451 Gene3D G3DSA:3.40.120.10 1 147 4.7E-53 T 23-10-2018 A3L04_08755 37503de404eb338096921bfe0d564ea4 451 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 151 246 1.9E-20 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_02325 5133993ba7ac022e479ef342d7110f0e 184 Pfam PF01725 Ham1 family 3 178 3.7E-50 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 A3L04_02325 5133993ba7ac022e479ef342d7110f0e 184 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 181 41.622 T 23-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 A3L04_02325 5133993ba7ac022e479ef342d7110f0e 184 Gene3D G3DSA:3.90.950.10 1 184 1.3E-76 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L04_02325 5133993ba7ac022e479ef342d7110f0e 184 SUPERFAMILY SSF52972 1 182 4.97E-62 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L04_02325 5133993ba7ac022e479ef342d7110f0e 184 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 2 179 3.7E-65 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 A3L04_07520 ba016d8012125574427a1a3dfdc1d768 192 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 25 136 3.2E-19 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07520 ba016d8012125574427a1a3dfdc1d768 192 SUPERFAMILY SSF56770 6 155 2.75E-54 T 23-10-2018 A3L04_07520 ba016d8012125574427a1a3dfdc1d768 192 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 8 142 1.6E-44 T 23-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07520 ba016d8012125574427a1a3dfdc1d768 192 Gene3D G3DSA:3.40.50.12280 2 163 5.7E-53 T 23-10-2018 A3L04_04140 06beb1bd192b6e57c305cd59f4e4f767 112 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 7 109 25.158 T 23-10-2018 IPR002765 Uncharacterised protein family UPF0145 A3L04_04140 06beb1bd192b6e57c305cd59f4e4f767 112 Gene3D G3DSA:3.30.110.70 7 112 4.4E-33 T 23-10-2018 A3L04_04140 06beb1bd192b6e57c305cd59f4e4f767 112 SUPERFAMILY SSF117782 8 111 1.7E-36 T 23-10-2018 IPR035439 UPF0145 domain superfamily A3L04_04140 06beb1bd192b6e57c305cd59f4e4f767 112 Pfam PF01906 Putative heavy-metal-binding 7 109 2.0E-37 T 23-10-2018 IPR002765 Uncharacterised protein family UPF0145 A3L04_09965 60495f3de2c7813f0c47505cb62752b9 414 Pfam PF12327 FtsZ family, C-terminal domain 251 345 5.1E-23 T 23-10-2018 IPR024757 Cell division protein FtsZ, C-terminal A3L04_09965 60495f3de2c7813f0c47505cb62752b9 414 ProSitePatterns PS01135 FtsZ protein signature 2. 119 140 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A3L04_09965 60495f3de2c7813f0c47505cb62752b9 414 SMART SM00865 236 353 3.2E-35 T 23-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 A3L04_09965 60495f3de2c7813f0c47505cb62752b9 414 SUPERFAMILY SSF55307 236 352 1.51E-33 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A3L04_09965 60495f3de2c7813f0c47505cb62752b9 414 ProSitePatterns PS01134 FtsZ protein signature 1. 66 100 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A3L04_09965 60495f3de2c7813f0c47505cb62752b9 414 SMART SM00864 35 234 5.1E-83 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L04_09965 60495f3de2c7813f0c47505cb62752b9 414 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 32 354 8.7E-109 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A3L04_09965 60495f3de2c7813f0c47505cb62752b9 414 Gene3D G3DSA:3.40.50.1440 32 345 2.3E-98 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L04_09965 60495f3de2c7813f0c47505cb62752b9 414 SUPERFAMILY SSF52490 34 237 2.22E-58 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L04_09965 60495f3de2c7813f0c47505cb62752b9 414 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 35 203 4.9E-42 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L04_09965 60495f3de2c7813f0c47505cb62752b9 414 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 31 410 33.008 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A3L04_09965 60495f3de2c7813f0c47505cb62752b9 414 PRINTS PR00423 Cell division protein FtsZ signature 156 177 2.4E-33 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L04_09965 60495f3de2c7813f0c47505cb62752b9 414 PRINTS PR00423 Cell division protein FtsZ signature 218 240 2.4E-33 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L04_09965 60495f3de2c7813f0c47505cb62752b9 414 PRINTS PR00423 Cell division protein FtsZ signature 241 262 2.4E-33 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L04_09965 60495f3de2c7813f0c47505cb62752b9 414 PRINTS PR00423 Cell division protein FtsZ signature 120 140 2.4E-33 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L04_03785 f181f41c273a0d99e630ba7a58ee68e7 345 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 317 1.7E-84 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A3L04_03785 f181f41c273a0d99e630ba7a58ee68e7 345 SMART SM01329 3 315 1.6E-136 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A3L04_03785 f181f41c273a0d99e630ba7a58ee68e7 345 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 214 233 - T 23-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A3L04_03785 f181f41c273a0d99e630ba7a58ee68e7 345 Gene3D G3DSA:3.40.718.10 1 332 1.2E-136 T 23-10-2018 A3L04_03785 f181f41c273a0d99e630ba7a58ee68e7 345 TIGRFAM TIGR02088 LEU3_arch: isopropylmalate/isohomocitrate dehydrogenases 4 316 1.1E-130 T 23-10-2018 IPR011828 Isopropylmalate/isohomocitrate dehydrogenase GO:0003862|GO:0009098|GO:0051287|GO:0055114 A3L04_03785 f181f41c273a0d99e630ba7a58ee68e7 345 SUPERFAMILY SSF53659 2 318 4.42E-102 T 23-10-2018 A3L04_06960 eb211444e1a5c96b3ff6fe40cb7b045f 250 SMART SM00849 4 222 2.4E-14 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_06960 eb211444e1a5c96b3ff6fe40cb7b045f 250 Gene3D G3DSA:3.60.15.10 1 250 5.0E-76 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_06960 eb211444e1a5c96b3ff6fe40cb7b045f 250 Pfam PF00753 Metallo-beta-lactamase superfamily 5 127 5.9E-20 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_06960 eb211444e1a5c96b3ff6fe40cb7b045f 250 SUPERFAMILY SSF56281 2 236 6.55E-38 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_04055 91b8aaf9f8a67e2851d14b108f4f5a09 148 Pfam PF01037 Lrp/AsnC ligand binding domain 69 138 1.1E-14 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L04_04055 91b8aaf9f8a67e2851d14b108f4f5a09 148 SMART SM00344 3 109 1.3E-43 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L04_04055 91b8aaf9f8a67e2851d14b108f4f5a09 148 Gene3D G3DSA:3.30.70.920 55 146 1.3E-22 T 23-10-2018 A3L04_04055 91b8aaf9f8a67e2851d14b108f4f5a09 148 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 50 2.0E-16 T 23-10-2018 A3L04_04055 91b8aaf9f8a67e2851d14b108f4f5a09 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.8E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_04055 91b8aaf9f8a67e2851d14b108f4f5a09 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.8E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_04055 91b8aaf9f8a67e2851d14b108f4f5a09 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.8E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_04055 91b8aaf9f8a67e2851d14b108f4f5a09 148 SUPERFAMILY SSF54909 63 145 4.96E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L04_04055 91b8aaf9f8a67e2851d14b108f4f5a09 148 SUPERFAMILY SSF46785 2 63 2.82E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_04055 91b8aaf9f8a67e2851d14b108f4f5a09 148 Gene3D G3DSA:1.10.10.10 1 53 2.7E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_07940 cd30a72947d5a9ee8ed9e9187283d079 142 SMART SM01072 12 74 1.9E-7 T 23-10-2018 IPR004201 CDC48, domain 2 A3L04_07940 cd30a72947d5a9ee8ed9e9187283d079 142 Gene3D G3DSA:2.40.10.360 82 142 1.1E-20 T 23-10-2018 A3L04_07940 cd30a72947d5a9ee8ed9e9187283d079 142 Gene3D G3DSA:3.10.330.10 1 77 3.9E-32 T 23-10-2018 A3L04_07940 cd30a72947d5a9ee8ed9e9187283d079 142 SUPERFAMILY SSF54585 2 73 7.85E-14 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily A3L04_07940 cd30a72947d5a9ee8ed9e9187283d079 142 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 13 68 1.8E-8 T 23-10-2018 IPR004201 CDC48, domain 2 A3L04_06550 7d08a3b69c71e518841b4a72f5af2da1 207 Gene3D G3DSA:3.20.20.70 2 207 1.7E-80 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_06550 7d08a3b69c71e518841b4a72f5af2da1 207 SUPERFAMILY SSF51391 5 203 2.22E-67 T 23-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L04_06550 7d08a3b69c71e518841b4a72f5af2da1 207 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 6 203 28.546 T 23-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L04_06550 7d08a3b69c71e518841b4a72f5af2da1 207 Pfam PF02581 Thiamine monophosphate synthase 9 185 9.6E-65 T 23-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L04_06550 7d08a3b69c71e518841b4a72f5af2da1 207 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 8 198 1.7E-66 T 23-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L04_02595 ca9683be1e72aba8540e2ea615e968d4 324 Pfam PF00534 Glycosyl transferases group 1 157 274 6.8E-23 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L04_02595 ca9683be1e72aba8540e2ea615e968d4 324 Gene3D G3DSA:3.40.50.2000 160 311 2.3E-29 T 23-10-2018 A3L04_02595 ca9683be1e72aba8540e2ea615e968d4 324 Pfam PF13439 Glycosyltransferase Family 4 27 151 2.8E-10 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L04_02595 ca9683be1e72aba8540e2ea615e968d4 324 Gene3D G3DSA:3.40.50.2000 5 159 1.5E-10 T 23-10-2018 A3L04_02595 ca9683be1e72aba8540e2ea615e968d4 324 SUPERFAMILY SSF53756 13 311 4.54E-53 T 23-10-2018 A3L04_08485 c2bd8030ba4450e2cdae62b0ede53281 963 SUPERFAMILY SSF52540 464 838 2.06E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_08485 c2bd8030ba4450e2cdae62b0ede53281 963 SMART SM00382 473 835 4.3E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_08485 c2bd8030ba4450e2cdae62b0ede53281 963 Gene3D G3DSA:3.40.50.300 463 563 3.3E-5 T 23-10-2018 A3L04_08485 c2bd8030ba4450e2cdae62b0ede53281 963 Pfam PF07728 AAA domain (dynein-related subfamily) 749 825 2.4E-7 T 23-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 A3L04_08650 9cdf9a8dfc8cf7b298631205b1964020 654 Gene3D G3DSA:2.40.30.270 29 123 1.0E-94 T 23-10-2018 A3L04_08650 9cdf9a8dfc8cf7b298631205b1964020 654 Gene3D G3DSA:3.40.50.300 448 653 5.6E-63 T 23-10-2018 A3L04_08650 9cdf9a8dfc8cf7b298631205b1964020 654 SMART SM00487 167 449 0.0071 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L04_08650 9cdf9a8dfc8cf7b298631205b1964020 654 TIGRFAM TIGR00376 TIGR00376: putative DNA helicase 15 647 1.7E-252 T 23-10-2018 IPR004483 Helicase SMUBP-2/Hcs1-like GO:0003677|GO:0005524 A3L04_08650 9cdf9a8dfc8cf7b298631205b1964020 654 Pfam PF13087 AAA domain 425 625 2.0E-58 T 23-10-2018 A3L04_08650 9cdf9a8dfc8cf7b298631205b1964020 654 Pfam PF13086 AAA domain 171 419 5.8E-55 T 23-10-2018 A3L04_08650 9cdf9a8dfc8cf7b298631205b1964020 654 SUPERFAMILY SSF52540 164 637 2.88E-66 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_08650 9cdf9a8dfc8cf7b298631205b1964020 654 Gene3D G3DSA:3.40.50.300 10 431 1.0E-94 T 23-10-2018 A3L04_09710 d203079dafafc61c5a7faab6b10d36cb 406 Pfam PF02163 Peptidase family M50 295 336 1.1E-6 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L04_08555 fdbad54959f229b80d322c9b9b45fb88 935 SUPERFAMILY SSF58100 739 903 1.7E-5 T 23-10-2018 A3L04_08555 fdbad54959f229b80d322c9b9b45fb88 935 Pfam PF13476 AAA domain 5 228 4.1E-25 T 23-10-2018 IPR038729 Rad50/SbcC-type AAA domain A3L04_08555 fdbad54959f229b80d322c9b9b45fb88 935 SUPERFAMILY SSF75712 572 667 5.23E-14 T 23-10-2018 A3L04_08555 fdbad54959f229b80d322c9b9b45fb88 935 SUPERFAMILY SSF52540 1 268 1.33E-30 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_08555 fdbad54959f229b80d322c9b9b45fb88 935 Gene3D G3DSA:1.10.287.510 567 678 7.6E-12 T 23-10-2018 A3L04_08555 fdbad54959f229b80d322c9b9b45fb88 935 Pfam PF04423 Rad50 zinc hook motif 598 644 4.1E-8 T 23-10-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A3L04_08555 fdbad54959f229b80d322c9b9b45fb88 935 Gene3D G3DSA:3.40.50.300 1 251 4.1E-52 T 23-10-2018 A3L04_07440 138dbdaaa504284cfa3c93413da2043e 629 Pfam PF02934 GatB/GatE catalytic domain 13 444 1.3E-65 T 23-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 A3L04_07440 138dbdaaa504284cfa3c93413da2043e 629 Pfam PF02637 GatB domain 485 624 1.0E-26 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A3L04_07440 138dbdaaa504284cfa3c93413da2043e 629 Hamap MF_00588 Glutamyl-tRNA(Gln) amidotransferase subunit E [gatE]. 1 629 337.248 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 A3L04_07440 138dbdaaa504284cfa3c93413da2043e 629 Pfam PF02938 GAD domain 299 390 2.1E-18 T 23-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 A3L04_07440 138dbdaaa504284cfa3c93413da2043e 629 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 177 191 - T 23-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 A3L04_07440 138dbdaaa504284cfa3c93413da2043e 629 SUPERFAMILY SSF89095 482 625 2.35E-27 T 23-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 A3L04_07440 138dbdaaa504284cfa3c93413da2043e 629 Gene3D G3DSA:1.10.10.410 566 625 3.9E-13 T 23-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal A3L04_07440 138dbdaaa504284cfa3c93413da2043e 629 SMART SM00845 484 624 5.0E-35 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A3L04_07440 138dbdaaa504284cfa3c93413da2043e 629 Gene3D G3DSA:3.30.1360.30 274 404 1.7E-54 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A3L04_07440 138dbdaaa504284cfa3c93413da2043e 629 SUPERFAMILY SSF55931 3 453 1.63E-100 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A3L04_07440 138dbdaaa504284cfa3c93413da2043e 629 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 282 406 9.0E-61 T 23-10-2018 A3L04_07440 138dbdaaa504284cfa3c93413da2043e 629 SUPERFAMILY SSF55261 278 404 8.5E-48 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A3L04_07440 138dbdaaa504284cfa3c93413da2043e 629 TIGRFAM TIGR00134 gatE_arch: glutamyl-tRNA(Gln) amidotransferase, subunit E 5 626 1.9E-242 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 A3L04_07440 138dbdaaa504284cfa3c93413da2043e 629 Gene3D G3DSA:1.10.150.380 453 545 8.7E-24 T 23-10-2018 A3L04_01265 bd66c2b5c601ae62ef010a41c18b8908 642 SUPERFAMILY SSF54862 577 634 2.09E-14 T 23-10-2018 A3L04_01265 bd66c2b5c601ae62ef010a41c18b8908 642 SUPERFAMILY SSF52402 236 428 2.3E-43 T 23-10-2018 A3L04_01265 bd66c2b5c601ae62ef010a41c18b8908 642 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 618 629 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_01265 bd66c2b5c601ae62ef010a41c18b8908 642 Gene3D G3DSA:3.30.70.20 583 634 3.2E-12 T 23-10-2018 A3L04_01265 bd66c2b5c601ae62ef010a41c18b8908 642 SMART SM00359 144 218 9.7E-18 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L04_01265 bd66c2b5c601ae62ef010a41c18b8908 642 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 587 598 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_01265 bd66c2b5c601ae62ef010a41c18b8908 642 SUPERFAMILY SSF88697 143 215 6.08E-17 T 23-10-2018 IPR015947 PUA-like superfamily A3L04_01265 bd66c2b5c601ae62ef010a41c18b8908 642 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 264 439 1.0E-45 T 23-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 A3L04_01265 bd66c2b5c601ae62ef010a41c18b8908 642 Gene3D G3DSA:2.30.130.10 141 218 5.1E-15 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L04_01265 bd66c2b5c601ae62ef010a41c18b8908 642 Gene3D G3DSA:3.40.50.620 231 453 2.6E-48 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_01265 bd66c2b5c601ae62ef010a41c18b8908 642 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 105 213 1.1E-13 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L04_01265 bd66c2b5c601ae62ef010a41c18b8908 642 Pfam PF12838 4Fe-4S dicluster domain 587 629 3.6E-10 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L04_01265 bd66c2b5c601ae62ef010a41c18b8908 642 Pfam PF01472 PUA domain 145 215 5.9E-16 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L04_03355 7bedfd5c119357ed1ae6b9e9d9caf4f5 399 Pfam PF01966 HD domain 39 165 4.0E-18 T 23-10-2018 IPR006674 HD domain A3L04_03355 7bedfd5c119357ed1ae6b9e9d9caf4f5 399 SUPERFAMILY SSF109604 7 393 6.91E-89 T 23-10-2018 A3L04_03355 7bedfd5c119357ed1ae6b9e9d9caf4f5 399 SMART SM00471 35 171 7.1E-13 T 23-10-2018 IPR003607 HD/PDEase domain A3L04_03355 7bedfd5c119357ed1ae6b9e9d9caf4f5 399 Gene3D G3DSA:1.10.3210.10 1 262 4.2E-82 T 23-10-2018 A3L04_04275 4331933c683bcce51108aa0a593c1be5 427 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 23-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A3L04_04275 4331933c683bcce51108aa0a593c1be5 427 SUPERFAMILY SSF53383 4 423 6.99E-133 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L04_04275 4331933c683bcce51108aa0a593c1be5 427 Gene3D G3DSA:3.90.1150.10 282 425 1.2E-52 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L04_04275 4331933c683bcce51108aa0a593c1be5 427 Gene3D G3DSA:3.40.640.10 32 281 3.6E-82 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L04_04275 4331933c683bcce51108aa0a593c1be5 427 PIRSF PIRSF000412 1 423 3.0E-145 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A3L04_04275 4331933c683bcce51108aa0a593c1be5 427 Pfam PF00464 Serine hydroxymethyltransferase 8 388 2.3E-79 T 23-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A3L04_04275 4331933c683bcce51108aa0a593c1be5 427 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 416 43.037 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A3L04_00785 03867b25409f397963e6b8ed8db3be30 388 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 10 187 8.1E-44 T 23-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L04_00785 03867b25409f397963e6b8ed8db3be30 388 PIRSF PIRSF001259 1 387 7.3E-132 T 23-10-2018 A3L04_00785 03867b25409f397963e6b8ed8db3be30 388 SUPERFAMILY SSF142695 194 362 1.1E-58 T 23-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A3L04_00785 03867b25409f397963e6b8ed8db3be30 388 Gene3D G3DSA:3.90.870.10 3 195 3.6E-46 T 23-10-2018 A3L04_00785 03867b25409f397963e6b8ed8db3be30 388 SUPERFAMILY SSF55821 4 187 1.56E-46 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A3L04_00785 03867b25409f397963e6b8ed8db3be30 388 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 194 386 38.267 T 23-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A3L04_00785 03867b25409f397963e6b8ed8db3be30 388 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 201 383 1.8E-68 T 23-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A3L04_00785 03867b25409f397963e6b8ed8db3be30 388 Pfam PF00925 GTP cyclohydrolase II 201 360 6.3E-65 T 23-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A3L04_00785 03867b25409f397963e6b8ed8db3be30 388 Gene3D G3DSA:3.40.50.10990 196 360 2.1E-67 T 23-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A3L04_10480 8e7574526534dc72d78dcf8321253d15 392 SMART SM00116 75 123 0.027 T 23-10-2018 IPR000644 CBS domain A3L04_10480 8e7574526534dc72d78dcf8321253d15 392 SMART SM00116 139 187 2.3E-13 T 23-10-2018 IPR000644 CBS domain A3L04_10480 8e7574526534dc72d78dcf8321253d15 392 SMART SM00116 217 265 1.6E-9 T 23-10-2018 IPR000644 CBS domain A3L04_10480 8e7574526534dc72d78dcf8321253d15 392 Gene3D G3DSA:3.10.580.10 207 301 1.1E-15 T 23-10-2018 A3L04_10480 8e7574526534dc72d78dcf8321253d15 392 Gene3D G3DSA:3.10.580.10 125 206 5.3E-21 T 23-10-2018 A3L04_10480 8e7574526534dc72d78dcf8321253d15 392 Pfam PF00571 CBS domain 132 183 1.4E-18 T 23-10-2018 IPR000644 CBS domain A3L04_10480 8e7574526534dc72d78dcf8321253d15 392 Pfam PF00571 CBS domain 69 122 2.7E-6 T 23-10-2018 IPR000644 CBS domain A3L04_10480 8e7574526534dc72d78dcf8321253d15 392 Pfam PF00571 CBS domain 212 261 1.3E-12 T 23-10-2018 IPR000644 CBS domain A3L04_10480 8e7574526534dc72d78dcf8321253d15 392 Gene3D G3DSA:3.10.580.10 4 124 2.7E-17 T 23-10-2018 A3L04_10480 8e7574526534dc72d78dcf8321253d15 392 PIRSF PIRSF036983 2 391 1.4E-143 T 23-10-2018 IPR014651 Uncharacterised conserved protein, 2xCBS, MJ1404 type A3L04_10480 8e7574526534dc72d78dcf8321253d15 392 SUPERFAMILY SSF54631 4 122 1.89E-18 T 23-10-2018 A3L04_10480 8e7574526534dc72d78dcf8321253d15 392 SUPERFAMILY SSF54631 123 261 4.57E-37 T 23-10-2018 A3L04_02890 9cfe90bdaaf24fd2b9a9d42e7c6bab49 234 Gene3D G3DSA:3.40.50.11570 4 217 1.8E-48 T 23-10-2018 A3L04_02890 9cfe90bdaaf24fd2b9a9d42e7c6bab49 234 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 9 215 2.3E-48 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L04_04230 52ee71fb7b88610b1d48bb57a2e11ccc 282 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 56 204 4.3E-39 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L04_04230 52ee71fb7b88610b1d48bb57a2e11ccc 282 Gene3D G3DSA:3.40.50.970 68 269 1.3E-32 T 23-10-2018 A3L04_04230 52ee71fb7b88610b1d48bb57a2e11ccc 282 SUPERFAMILY SSF52518 18 270 2.4E-77 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L04_03410 a0e6b4080e0369bda5ec4a94b837a0eb 68 Pfam PF00831 Ribosomal L29 protein 4 61 8.8E-18 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03410 a0e6b4080e0369bda5ec4a94b837a0eb 68 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 61 9.3E-21 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03410 a0e6b4080e0369bda5ec4a94b837a0eb 68 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 61 14.991 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03410 a0e6b4080e0369bda5ec4a94b837a0eb 68 Gene3D G3DSA:1.10.287.310 1 66 7.0E-19 T 23-10-2018 A3L04_03410 a0e6b4080e0369bda5ec4a94b837a0eb 68 SUPERFAMILY SSF46561 2 62 9.81E-16 T 23-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03410 a0e6b4080e0369bda5ec4a94b837a0eb 68 ProSitePatterns PS00579 Ribosomal protein L29 signature. 40 54 - T 23-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_01460 8a0d6752f47c8dff74ef71184d3cdb95 419 SMART SM01074 315 397 2.8E-38 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 A3L04_01460 8a0d6752f47c8dff74ef71184d3cdb95 419 Gene3D G3DSA:1.10.10.10 307 408 5.3E-32 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_01460 8a0d6752f47c8dff74ef71184d3cdb95 419 SUPERFAMILY SSF46785 300 406 5.8E-32 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_01460 8a0d6752f47c8dff74ef71184d3cdb95 419 SUPERFAMILY SSF52540 22 294 2.13E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01460 8a0d6752f47c8dff74ef71184d3cdb95 419 Pfam PF09079 CDC6, C terminal winged helix domain 315 394 2.0E-26 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 A3L04_01460 8a0d6752f47c8dff74ef71184d3cdb95 419 Gene3D G3DSA:1.10.8.60 22 298 4.6E-111 T 23-10-2018 A3L04_01460 8a0d6752f47c8dff74ef71184d3cdb95 419 Hamap MF_01407 ORC1-type DNA replication protein. 15 397 34.455 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea A3L04_01460 8a0d6752f47c8dff74ef71184d3cdb95 419 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 65 207 7.9E-10 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L04_01460 8a0d6752f47c8dff74ef71184d3cdb95 419 Gene3D G3DSA:3.40.50.300 38 219 4.6E-111 T 23-10-2018 A3L04_01460 8a0d6752f47c8dff74ef71184d3cdb95 419 SMART SM00382 60 221 7.9E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_01460 8a0d6752f47c8dff74ef71184d3cdb95 419 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 22 386 4.6E-152 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea A3L04_07245 41d78e850461d11e61339c546cdea2e6 126 Gene3D G3DSA:3.40.1350.10 1 122 1.7E-44 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A3L04_07245 41d78e850461d11e61339c546cdea2e6 126 SUPERFAMILY SSF52980 1 92 8.71E-28 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L04_07245 41d78e850461d11e61339c546cdea2e6 126 Pfam PF01870 Archaeal holliday junction resolvase (hjc) 8 93 9.7E-31 T 23-10-2018 IPR002732 Holliday junction resolvase Hjc A3L04_07245 41d78e850461d11e61339c546cdea2e6 126 ProDom PD015874 RESOLVASE HOLLIDAY JUNCTION ARCHAEAL HOLLIDAY-JUNCTION TYPE MJ0497 ORF-C21_024 PF1503 NEQ424 9 118 3.0E-36 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal A3L04_07245 41d78e850461d11e61339c546cdea2e6 126 Hamap MF_01490 Holliday junction resolvase Hjc [hjc]. 1 118 34.266 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal A3L04_07245 41d78e850461d11e61339c546cdea2e6 126 PIRSF PIRSF004985 1 118 2.0E-37 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal A3L04_08350 ed5e3f2ed9633e38f3176051961dd369 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 277 4.3E-27 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L04_08350 ed5e3f2ed9633e38f3176051961dd369 282 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 22 57 3.0E-6 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A3L04_08350 ed5e3f2ed9633e38f3176051961dd369 282 SUPERFAMILY SSF161098 75 265 9.55E-27 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_08350 ed5e3f2ed9633e38f3176051961dd369 282 Gene3D G3DSA:1.10.3720.10 68 279 1.4E-22 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_04080 6bae6b50426c851c325c8e62c8b50e20 572 TIGRFAM TIGR00463 gltX_arch: glutamate--tRNA ligase 4 572 2.9E-214 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L04_04080 6bae6b50426c851c325c8e62c8b50e20 572 Hamap MF_02076 Glutamate--tRNA ligase [gltX]. 7 570 40.421 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L04_04080 6bae6b50426c851c325c8e62c8b50e20 572 SUPERFAMILY SSF50715 409 569 2.14E-32 T 23-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L04_04080 6bae6b50426c851c325c8e62c8b50e20 572 Gene3D G3DSA:2.40.240.10 418 516 3.5E-44 T 23-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L04_04080 6bae6b50426c851c325c8e62c8b50e20 572 PRINTS PR00987 Glutamyl-tRNA synthetase signature 103 115 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L04_04080 6bae6b50426c851c325c8e62c8b50e20 572 PRINTS PR00987 Glutamyl-tRNA synthetase signature 117 128 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L04_04080 6bae6b50426c851c325c8e62c8b50e20 572 PRINTS PR00987 Glutamyl-tRNA synthetase signature 132 145 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L04_04080 6bae6b50426c851c325c8e62c8b50e20 572 PRINTS PR00987 Glutamyl-tRNA synthetase signature 296 304 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L04_04080 6bae6b50426c851c325c8e62c8b50e20 572 PRINTS PR00987 Glutamyl-tRNA synthetase signature 280 290 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L04_04080 6bae6b50426c851c325c8e62c8b50e20 572 Gene3D G3DSA:2.40.240.100 409 571 3.5E-44 T 23-10-2018 A3L04_04080 6bae6b50426c851c325c8e62c8b50e20 572 SUPERFAMILY SSF52374 99 415 5.09E-92 T 23-10-2018 A3L04_04080 6bae6b50426c851c325c8e62c8b50e20 572 Gene3D G3DSA:3.40.50.620 93 408 5.0E-122 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_04080 6bae6b50426c851c325c8e62c8b50e20 572 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 409 558 1.4E-31 T 23-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L04_04080 6bae6b50426c851c325c8e62c8b50e20 572 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 99 404 1.0E-86 T 23-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 A3L04_06640 86498ae41bee6df418ea1b989eac393d 120 Pfam PF03874 RNA polymerase Rpb4 11 119 1.2E-10 T 23-10-2018 IPR005574 RNA polymerase subunit RPB4/RPC9 GO:0006352|GO:0030880 A3L04_06640 86498ae41bee6df418ea1b989eac393d 120 Gene3D G3DSA:1.10.287.420 1 54 1.0E-23 T 23-10-2018 A3L04_06640 86498ae41bee6df418ea1b989eac393d 120 PIRSF PIRSF005053 1 120 2.7E-37 T 23-10-2018 IPR010924 DNA-directed RNA polymerase subunit F (Rpo4) A3L04_06640 86498ae41bee6df418ea1b989eac393d 120 Gene3D G3DSA:1.10.150.80 55 120 1.1E-23 T 23-10-2018 A3L04_06640 86498ae41bee6df418ea1b989eac393d 120 SUPERFAMILY SSF47819 1 115 1.87E-26 T 23-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 A3L04_09450 9f69aef0a3c7b8d4bfcfe0f8bada260a 315 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 310 2.0E-150 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L04_09450 9f69aef0a3c7b8d4bfcfe0f8bada260a 315 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 1.0E-53 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A3L04_09450 9f69aef0a3c7b8d4bfcfe0f8bada260a 315 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 308 7.1E-66 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A3L04_09450 9f69aef0a3c7b8d4bfcfe0f8bada260a 315 SUPERFAMILY SSF53671 4 312 2.75E-119 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L04_09450 9f69aef0a3c7b8d4bfcfe0f8bada260a 315 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 311 87.247 T 23-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 A3L04_09450 9f69aef0a3c7b8d4bfcfe0f8bada260a 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 3.0E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L04_09450 9f69aef0a3c7b8d4bfcfe0f8bada260a 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 3.0E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L04_09450 9f69aef0a3c7b8d4bfcfe0f8bada260a 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 289 300 3.0E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L04_09450 9f69aef0a3c7b8d4bfcfe0f8bada260a 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 3.0E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L04_09450 9f69aef0a3c7b8d4bfcfe0f8bada260a 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 227 237 3.0E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L04_09450 9f69aef0a3c7b8d4bfcfe0f8bada260a 315 Gene3D G3DSA:3.40.50.1370 9 307 4.8E-143 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L04_09450 9f69aef0a3c7b8d4bfcfe0f8bada260a 315 Gene3D G3DSA:3.40.50.1370 138 297 4.8E-143 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L04_09450 9f69aef0a3c7b8d4bfcfe0f8bada260a 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 263 272 1.0E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L04_09450 9f69aef0a3c7b8d4bfcfe0f8bada260a 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 1.0E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L04_09450 9f69aef0a3c7b8d4bfcfe0f8bada260a 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 1.0E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L04_09450 9f69aef0a3c7b8d4bfcfe0f8bada260a 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 275 298 1.0E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L04_09450 9f69aef0a3c7b8d4bfcfe0f8bada260a 315 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L04_05715 f2885efea31afa684391c9a06b5bf10e 262 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 218 1.3E-55 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L04_05715 f2885efea31afa684391c9a06b5bf10e 262 SUPERFAMILY SSF55120 1 231 1.73E-66 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L04_05715 f2885efea31afa684391c9a06b5bf10e 262 Gene3D G3DSA:3.30.70.580 1 96 4.1E-25 T 23-10-2018 A3L04_05715 f2885efea31afa684391c9a06b5bf10e 262 Gene3D G3DSA:3.30.70.660 97 222 1.7E-28 T 23-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 A3L04_05715 f2885efea31afa684391c9a06b5bf10e 262 PIRSF PIRSF001430 1 239 2.5E-72 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L04_05715 f2885efea31afa684391c9a06b5bf10e 262 Pfam PF01416 tRNA pseudouridine synthase 125 224 5.6E-22 T 23-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L04_05715 f2885efea31afa684391c9a06b5bf10e 262 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 223 32.628 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L04_09240 cb9a96817c23f9bfdf5550e29782b9c0 345 Gene3D G3DSA:3.20.20.70 114 330 3.9E-27 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_09240 cb9a96817c23f9bfdf5550e29782b9c0 345 SUPERFAMILY SSF102114 109 328 6.02E-22 T 23-10-2018 A3L04_09240 cb9a96817c23f9bfdf5550e29782b9c0 345 Pfam PF04055 Radical SAM superfamily 122 272 2.8E-18 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_09240 cb9a96817c23f9bfdf5550e29782b9c0 345 PIRSF PIRSF004869 3 344 1.8E-76 T 23-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted A3L04_09240 cb9a96817c23f9bfdf5550e29782b9c0 345 Pfam PF13353 4Fe-4S single cluster domain 119 208 2.2E-6 T 23-10-2018 A3L04_02195 3391a0e2edc5011756f33da58a577a23 430 Gene3D G3DSA:3.20.20.120 129 429 1.4E-132 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A3L04_02195 3391a0e2edc5011756f33da58a577a23 430 Gene3D G3DSA:3.30.390.10 2 127 2.0E-57 T 23-10-2018 IPR029017 Enolase-like, N-terminal A3L04_02195 3391a0e2edc5011756f33da58a577a23 430 SMART SM01192 140 428 1.2E-205 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_02195 3391a0e2edc5011756f33da58a577a23 430 SUPERFAMILY SSF54826 6 140 3.54E-58 T 23-10-2018 A3L04_02195 3391a0e2edc5011756f33da58a577a23 430 PIRSF PIRSF001400 3 428 3.9E-197 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_02195 3391a0e2edc5011756f33da58a577a23 430 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 427 6.3E-132 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_02195 3391a0e2edc5011756f33da58a577a23 430 SMART SM01193 7 135 6.2E-97 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_02195 3391a0e2edc5011756f33da58a577a23 430 SUPERFAMILY SSF51604 139 427 1.08E-124 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A3L04_02195 3391a0e2edc5011756f33da58a577a23 430 Hamap MF_00318 Enolase [eno]. 5 414 46.16 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_02195 3391a0e2edc5011756f33da58a577a23 430 Pfam PF03952 Enolase, N-terminal domain 7 135 1.2E-60 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_02195 3391a0e2edc5011756f33da58a577a23 430 PRINTS PR00148 Enolase signature 162 175 1.7E-49 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_02195 3391a0e2edc5011756f33da58a577a23 430 PRINTS PR00148 Enolase signature 108 124 1.7E-49 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_02195 3391a0e2edc5011756f33da58a577a23 430 PRINTS PR00148 Enolase signature 314 325 1.7E-49 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_02195 3391a0e2edc5011756f33da58a577a23 430 PRINTS PR00148 Enolase signature 39 53 1.7E-49 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_02195 3391a0e2edc5011756f33da58a577a23 430 PRINTS PR00148 Enolase signature 337 351 1.7E-49 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_02195 3391a0e2edc5011756f33da58a577a23 430 PRINTS PR00148 Enolase signature 366 383 1.7E-49 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_02195 3391a0e2edc5011756f33da58a577a23 430 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 7 426 3.0E-200 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_02195 3391a0e2edc5011756f33da58a577a23 430 ProSitePatterns PS00164 Enolase signature. 337 350 - T 23-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_01770 efc1595682a1a16441dc241a9c9b4a97 187 PIRSF PIRSF006503 1 187 5.9E-83 T 23-10-2018 IPR007162 Protein of unknown function DUF366 A3L04_01770 efc1595682a1a16441dc241a9c9b4a97 187 ProDom PD022700 PH0223 5/5 GENOME PF0133 SEGMENT UNCHARACTERIZED MA4198 MJ0805 4 185 3.0E-80 T 23-10-2018 IPR007162 Protein of unknown function DUF366 A3L04_01770 efc1595682a1a16441dc241a9c9b4a97 187 Gene3D G3DSA:3.30.930.10 1 187 2.4E-77 T 23-10-2018 A3L04_01770 efc1595682a1a16441dc241a9c9b4a97 187 Pfam PF04017 Domain of unknown function (DUF366) 5 184 5.5E-67 T 23-10-2018 IPR007162 Protein of unknown function DUF366 A3L04_01770 efc1595682a1a16441dc241a9c9b4a97 187 SUPERFAMILY SSF55681 3 186 1.19E-72 T 23-10-2018 A3L04_05550 e1f52788ecd90d2e2031a4360d981aea 97 SMART SM00418 5 93 0.0074 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_05550 e1f52788ecd90d2e2031a4360d981aea 97 SUPERFAMILY SSF46785 8 91 3.34E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_05550 e1f52788ecd90d2e2031a4360d981aea 97 Pfam PF13601 Winged helix DNA-binding domain 17 94 5.9E-18 T 23-10-2018 IPR027395 Winged helix DNA-binding domain A3L04_05550 e1f52788ecd90d2e2031a4360d981aea 97 Gene3D G3DSA:1.10.10.10 1 97 3.5E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_02130 0efae2af2babf867473213f241389bf0 624 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 30 240 1.3E-54 T 23-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L04_02130 0efae2af2babf867473213f241389bf0 624 SUPERFAMILY SSF53795 245 605 5.26E-111 T 23-10-2018 A3L04_02130 0efae2af2babf867473213f241389bf0 624 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 269 277 - T 23-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L04_02130 0efae2af2babf867473213f241389bf0 624 SUPERFAMILY SSF68923 13 244 5.75E-60 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A3L04_02130 0efae2af2babf867473213f241389bf0 624 PIRSF PIRSF001348 6 609 2.8E-220 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L04_02130 0efae2af2babf867473213f241389bf0 624 Gene3D G3DSA:3.90.228.20 248 604 1.2E-146 T 23-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A3L04_02130 0efae2af2babf867473213f241389bf0 624 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 245 605 9.5E-108 T 23-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L04_02130 0efae2af2babf867473213f241389bf0 624 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 19 606 37.571 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L04_02130 0efae2af2babf867473213f241389bf0 624 Gene3D G3DSA:2.170.8.10 66 399 1.2E-146 T 23-10-2018 A3L04_02130 0efae2af2babf867473213f241389bf0 624 Gene3D G3DSA:3.40.449.10 29 247 1.2E-146 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A3L04_04485 1ef3ac50bdc9d6d977164610fef10bee 164 SUPERFAMILY SSF159234 3 162 5.36E-36 T 23-10-2018 IPR035930 FomD-like superfamily A3L04_04485 1ef3ac50bdc9d6d977164610fef10bee 164 Pfam PF04167 Protein of unknown function (DUF402) 56 120 5.9E-12 T 23-10-2018 IPR007295 Domain of unknown function DUF402 A3L04_04485 1ef3ac50bdc9d6d977164610fef10bee 164 Gene3D G3DSA:2.40.380.10 39 162 3.8E-12 T 23-10-2018 IPR035930 FomD-like superfamily A3L04_06205 d1fea5099af5611ead737faa552f3524 175 SUPERFAMILY SSF88697 1 146 1.84E-16 T 23-10-2018 IPR015947 PUA-like superfamily A3L04_06205 d1fea5099af5611ead737faa552f3524 175 Pfam PF04266 ASCH domain 6 115 7.9E-5 T 23-10-2018 IPR007374 ASCH domain A3L04_06205 d1fea5099af5611ead737faa552f3524 175 SMART SM01022 5 110 9.7E-4 T 23-10-2018 IPR007374 ASCH domain A3L04_07335 cfa217e7a4d2c2fc7e9701c6b37da154 67 ProSitePatterns PS00712 Ribosomal protein S17e signature. 41 56 - T 23-10-2018 IPR018273 Ribosomal protein S17e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_07335 cfa217e7a4d2c2fc7e9701c6b37da154 67 Gene3D G3DSA:1.10.60.20 1 62 6.5E-30 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_07335 cfa217e7a4d2c2fc7e9701c6b37da154 67 SUPERFAMILY SSF116820 1 60 1.03E-23 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_07335 cfa217e7a4d2c2fc7e9701c6b37da154 67 Hamap MF_00511 30S ribosomal protein S17e [rps17e]. 1 63 22.153 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_07335 cfa217e7a4d2c2fc7e9701c6b37da154 67 Pfam PF00833 Ribosomal S17 1 64 8.1E-18 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03965 738beff72de3c3429819029a5887407c 1051 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 2 1033 13.966 T 23-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_03965 738beff72de3c3429819029a5887407c 1051 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 421 526 7.4E-27 T 23-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_03965 738beff72de3c3429819029a5887407c 1051 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 816 823 - T 23-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A3L04_03965 738beff72de3c3429819029a5887407c 1051 Gene3D G3DSA:3.40.50.20 504 643 6.8E-50 T 23-10-2018 A3L04_03965 738beff72de3c3429819029a5887407c 1051 Gene3D G3DSA:3.30.1490.20 667 736 4.1E-89 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L04_03965 738beff72de3c3429819029a5887407c 1051 SUPERFAMILY SSF52440 539 655 1.44E-38 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L04_03965 738beff72de3c3429819029a5887407c 1051 SUPERFAMILY SSF48108 391 534 3.4E-32 T 23-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_03965 738beff72de3c3429819029a5887407c 1051 SUPERFAMILY SSF56059 654 913 7.41E-80 T 23-10-2018 A3L04_03965 738beff72de3c3429819029a5887407c 1051 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 690 704 - T 23-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A3L04_03965 738beff72de3c3429819029a5887407c 1051 Gene3D G3DSA:3.40.50.20 1 113 5.0E-45 T 23-10-2018 A3L04_03965 738beff72de3c3429819029a5887407c 1051 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 16 30 4.0E-59 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_03965 738beff72de3c3429819029a5887407c 1051 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 236 253 4.0E-59 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_03965 738beff72de3c3429819029a5887407c 1051 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 201 220 4.0E-59 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_03965 738beff72de3c3429819029a5887407c 1051 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 45 55 4.0E-59 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_03965 738beff72de3c3429819029a5887407c 1051 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 375 393 4.0E-59 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_03965 738beff72de3c3429819029a5887407c 1051 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 293 322 4.0E-59 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_03965 738beff72de3c3429819029a5887407c 1051 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 165 177 4.0E-59 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_03965 738beff72de3c3429819029a5887407c 1051 SUPERFAMILY SSF52440 2 123 2.01E-42 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L04_03965 738beff72de3c3429819029a5887407c 1051 Gene3D G3DSA:1.10.1030.10 403 503 4.5E-19 T 23-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_03965 738beff72de3c3429819029a5887407c 1051 SUPERFAMILY SSF52335 930 1035 9.16E-8 T 23-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily A3L04_03965 738beff72de3c3429819029a5887407c 1051 Gene3D G3DSA:3.40.50.1380 930 1038 2.2E-5 T 23-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily A3L04_03965 738beff72de3c3429819029a5887407c 1051 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 3 1016 0.0 T 23-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_03965 738beff72de3c3429819029a5887407c 1051 Gene3D G3DSA:3.30.470.20 648 910 4.1E-89 T 23-10-2018 A3L04_03965 738beff72de3c3429819029a5887407c 1051 SUPERFAMILY SSF56059 125 396 1.45E-99 T 23-10-2018 A3L04_03965 738beff72de3c3429819029a5887407c 1051 Gene3D G3DSA:3.30.470.20 117 398 1.7E-119 T 23-10-2018 A3L04_03965 738beff72de3c3429819029a5887407c 1051 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 655 849 3.6E-30 T 23-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A3L04_03965 738beff72de3c3429819029a5887407c 1051 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 125 330 5.2E-71 T 23-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A3L04_03965 738beff72de3c3429819029a5887407c 1051 SMART SM01096 418 527 4.4E-36 T 23-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_10635 055b158067509d6628f4105888374f8a 78 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 44 4.7E-16 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L04_10635 055b158067509d6628f4105888374f8a 78 SUPERFAMILY SSF89447 1 64 1.73E-13 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L04_10635 055b158067509d6628f4105888374f8a 78 Gene3D G3DSA:2.10.260.10 2 42 1.0E-16 T 23-10-2018 A3L04_10635 055b158067509d6628f4105888374f8a 78 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 45 3.4E-11 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L04_10635 055b158067509d6628f4105888374f8a 78 SMART SM00966 4 49 4.1E-14 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L04_03445 0ed03c955b5f53adff281e039c3dd03a 186 Pfam PF00673 ribosomal L5P family C-terminus 75 173 1.6E-26 T 23-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03445 0ed03c955b5f53adff281e039c3dd03a 186 Pfam PF00281 Ribosomal protein L5 19 71 3.2E-21 T 23-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03445 0ed03c955b5f53adff281e039c3dd03a 186 PIRSF PIRSF002161 2 183 8.0E-57 T 23-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03445 0ed03c955b5f53adff281e039c3dd03a 186 Hamap MF_01333_A 50S ribosomal protein L5 [rplE]. 17 184 43.278 T 23-10-2018 IPR022804 Ribosomal protein L5, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_03445 0ed03c955b5f53adff281e039c3dd03a 186 SUPERFAMILY SSF55282 18 183 3.3E-58 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03445 0ed03c955b5f53adff281e039c3dd03a 186 Gene3D G3DSA:3.30.1440.10 13 186 6.4E-74 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_07715 7ffc29bef85a11ff26a6e427345cbb4f 207 SUPERFAMILY SSF56235 6 205 1.85E-66 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L04_07715 7ffc29bef85a11ff26a6e427345cbb4f 207 PRINTS PR00141 Proteasome component signature 149 160 2.1E-11 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L04_07715 7ffc29bef85a11ff26a6e427345cbb4f 207 PRINTS PR00141 Proteasome component signature 18 33 2.1E-11 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L04_07715 7ffc29bef85a11ff26a6e427345cbb4f 207 PRINTS PR00141 Proteasome component signature 138 149 2.1E-11 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L04_07715 7ffc29bef85a11ff26a6e427345cbb4f 207 PRINTS PR00141 Proteasome component signature 174 185 2.1E-11 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L04_07715 7ffc29bef85a11ff26a6e427345cbb4f 207 Pfam PF00227 Proteasome subunit 9 188 6.9E-56 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L04_07715 7ffc29bef85a11ff26a6e427345cbb4f 207 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 10 193 4.2E-80 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A3L04_07715 7ffc29bef85a11ff26a6e427345cbb4f 207 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 14 61 - T 23-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L04_07715 7ffc29bef85a11ff26a6e427345cbb4f 207 Gene3D G3DSA:3.60.20.10 5 207 1.6E-71 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L04_07715 7ffc29bef85a11ff26a6e427345cbb4f 207 Hamap MF_02113_A Proteasome subunit beta [prcB]. 6 200 36.094 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A3L04_09305 b5adfb84d13e9c3ef3e444993183982d 589 Gene3D G3DSA:3.40.50.300 1 326 7.7E-105 T 23-10-2018 A3L04_09305 b5adfb84d13e9c3ef3e444993183982d 589 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_09305 b5adfb84d13e9c3ef3e444993183982d 589 ProSitePatterns PS00211 ABC transporters family signature. 211 225 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_09305 b5adfb84d13e9c3ef3e444993183982d 589 SMART SM00382 363 531 3.6E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_09305 b5adfb84d13e9c3ef3e444993183982d 589 SMART SM00382 98 286 2.2E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_09305 b5adfb84d13e9c3ef3e444993183982d 589 Pfam PF00037 4Fe-4S binding domain 45 67 3.7E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L04_09305 b5adfb84d13e9c3ef3e444993183982d 589 SUPERFAMILY SSF52540 360 529 6.18E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09305 b5adfb84d13e9c3ef3e444993183982d 589 Gene3D G3DSA:3.40.50.300 327 589 7.1E-73 T 23-10-2018 A3L04_09305 b5adfb84d13e9c3ef3e444993183982d 589 PRINTS PR01868 ABC transporter family E signature 134 150 4.7E-64 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L04_09305 b5adfb84d13e9c3ef3e444993183982d 589 PRINTS PR01868 ABC transporter family E signature 103 128 4.7E-64 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L04_09305 b5adfb84d13e9c3ef3e444993183982d 589 PRINTS PR01868 ABC transporter family E signature 75 95 4.7E-64 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L04_09305 b5adfb84d13e9c3ef3e444993183982d 589 PRINTS PR01868 ABC transporter family E signature 150 176 4.7E-64 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L04_09305 b5adfb84d13e9c3ef3e444993183982d 589 PRINTS PR01868 ABC transporter family E signature 48 72 4.7E-64 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L04_09305 b5adfb84d13e9c3ef3e444993183982d 589 PRINTS PR01868 ABC transporter family E signature 20 35 4.7E-64 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L04_09305 b5adfb84d13e9c3ef3e444993183982d 589 Pfam PF00005 ABC transporter 360 482 7.3E-23 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_09305 b5adfb84d13e9c3ef3e444993183982d 589 SUPERFAMILY SSF52540 96 285 2.71E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09305 b5adfb84d13e9c3ef3e444993183982d 589 SUPERFAMILY SSF54862 4 123 1.09E-23 T 23-10-2018 A3L04_09305 b5adfb84d13e9c3ef3e444993183982d 589 ProSitePatterns PS00211 ABC transporters family signature. 454 468 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_09305 b5adfb84d13e9c3ef3e444993183982d 589 Pfam PF00005 ABC transporter 96 238 4.1E-18 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_09305 b5adfb84d13e9c3ef3e444993183982d 589 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 1 32 2.7E-11 T 23-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain A3L04_01235 4ab6e8a72546785d0df9c2de40642bf3 273 Gene3D G3DSA:3.40.190.10 5 171 2.0E-54 T 23-10-2018 A3L04_01235 4ab6e8a72546785d0df9c2de40642bf3 273 SUPERFAMILY SSF55021 181 264 2.15E-23 T 23-10-2018 A3L04_01235 4ab6e8a72546785d0df9c2de40642bf3 273 Pfam PF01842 ACT domain 190 253 3.5E-9 T 23-10-2018 IPR002912 ACT domain A3L04_01235 4ab6e8a72546785d0df9c2de40642bf3 273 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 217 224 - T 23-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A3L04_01235 4ab6e8a72546785d0df9c2de40642bf3 273 Pfam PF00800 Prephenate dehydratase 3 175 7.8E-55 T 23-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A3L04_01235 4ab6e8a72546785d0df9c2de40642bf3 273 SUPERFAMILY SSF53850 2 176 4.23E-53 T 23-10-2018 A3L04_01235 4ab6e8a72546785d0df9c2de40642bf3 273 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 149 171 - T 23-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A3L04_01235 4ab6e8a72546785d0df9c2de40642bf3 273 Gene3D G3DSA:3.40.190.10 81 162 2.0E-54 T 23-10-2018 A3L04_01235 4ab6e8a72546785d0df9c2de40642bf3 273 Gene3D G3DSA:3.30.70.260 183 268 5.8E-25 T 23-10-2018 A3L04_10725 c817084c818324a243d3b6fd1afb5fba 94 ProDom PD006030 RIBOSOMAL 60S L31 RIBONUCLEOPROTEIN L31E 50S L31 SUBUNIT STRAIN PHOSPHORYLATION 10 58 2.0E-18 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_10725 c817084c818324a243d3b6fd1afb5fba 94 SMART SM01380 8 87 2.1E-27 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_10725 c817084c818324a243d3b6fd1afb5fba 94 Gene3D G3DSA:3.10.440.10 2 90 4.1E-28 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_10725 c817084c818324a243d3b6fd1afb5fba 94 Pfam PF01198 Ribosomal protein L31e 12 85 1.0E-15 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_10725 c817084c818324a243d3b6fd1afb5fba 94 SUPERFAMILY SSF54575 7 85 1.31E-26 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_10725 c817084c818324a243d3b6fd1afb5fba 94 Hamap MF_00410 50S ribosomal protein L31e [rpl31e]. 4 94 24.041 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_10725 c817084c818324a243d3b6fd1afb5fba 94 ProSitePatterns PS01144 Ribosomal protein L31e signature. 48 62 - T 23-10-2018 IPR020052 Ribosomal protein L31e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_09840 28cd23df79f32b411dbadb0b27d80a2e 278 Gene3D G3DSA:3.40.50.150 87 278 3.1E-59 T 23-10-2018 A3L04_09840 28cd23df79f32b411dbadb0b27d80a2e 278 SUPERFAMILY SSF53335 19 276 8.0E-70 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_09840 28cd23df79f32b411dbadb0b27d80a2e 278 Pfam PF02475 Met-10+ like-protein 29 223 1.1E-70 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A3L04_09840 28cd23df79f32b411dbadb0b27d80a2e 278 Hamap MF_01922 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase [taw2]. 26 276 42.282 T 23-10-2018 IPR030867 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase GO:0006400|GO:0016765 MetaCyc: PWY-7286 A3L04_09840 28cd23df79f32b411dbadb0b27d80a2e 278 Gene3D G3DSA:3.30.300.110 19 86 4.3E-30 T 23-10-2018 A3L04_02300 05e530543e9e4ad725aaa86a8c30662d 86 SUPERFAMILY SSF158436 2 86 1.44E-30 T 23-10-2018 A3L04_02300 05e530543e9e4ad725aaa86a8c30662d 86 Pfam PF03685 Uncharacterised protein family (UPF0147) 5 85 1.6E-33 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 A3L04_02300 05e530543e9e4ad725aaa86a8c30662d 86 Hamap MF_00342 UPF0147 protein . 4 86 30.356 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 A3L04_02300 05e530543e9e4ad725aaa86a8c30662d 86 ProDom PD029943 UPF0147 ARCHAEAL PF0239 ST0460.1 MM1385 CYTOSOLIC SACI_0891 TV0625 APES069 TA0600 4 86 5.0E-39 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 A3L04_02300 05e530543e9e4ad725aaa86a8c30662d 86 Gene3D G3DSA:1.20.1440.50 3 86 1.3E-31 T 23-10-2018 IPR023130 Ta0600-like superfamily A3L04_00685 c3cf5759a8a3d2b5ba4c66a1e7abd1b1 854 SMART SM00490 453 538 3.3E-20 T 23-10-2018 IPR001650 Helicase, C-terminal A3L04_00685 c3cf5759a8a3d2b5ba4c66a1e7abd1b1 854 Pfam PF00270 DEAD/DEAH box helicase 220 382 5.7E-24 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L04_00685 c3cf5759a8a3d2b5ba4c66a1e7abd1b1 854 SUPERFAMILY SSF52540 228 552 3.51E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_00685 c3cf5759a8a3d2b5ba4c66a1e7abd1b1 854 Pfam PF00271 Helicase conserved C-terminal domain 426 536 6.0E-15 T 23-10-2018 IPR001650 Helicase, C-terminal A3L04_00685 c3cf5759a8a3d2b5ba4c66a1e7abd1b1 854 SMART SM00487 213 410 3.6E-30 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L04_00685 c3cf5759a8a3d2b5ba4c66a1e7abd1b1 854 Gene3D G3DSA:3.40.50.300 199 402 2.3E-52 T 23-10-2018 A3L04_00685 c3cf5759a8a3d2b5ba4c66a1e7abd1b1 854 Gene3D G3DSA:3.40.50.300 404 576 2.4E-30 T 23-10-2018 A3L04_05000 7c3f6d3b3ad070de5a952769f37d8925 76 Hamap MF_00257 Putative snRNP Sm-like protein. 1 72 26.126 T 23-10-2018 IPR022901 snRNP Sm-like, putative, archaea A3L04_05000 7c3f6d3b3ad070de5a952769f37d8925 76 SUPERFAMILY SSF50182 5 75 6.78E-19 T 23-10-2018 IPR010920 LSM domain superfamily A3L04_05000 7c3f6d3b3ad070de5a952769f37d8925 76 Pfam PF01423 LSM domain 8 72 5.1E-20 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type A3L04_05000 7c3f6d3b3ad070de5a952769f37d8925 76 SMART SM00651 7 72 1.2E-22 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type A3L04_05000 7c3f6d3b3ad070de5a952769f37d8925 76 Gene3D G3DSA:2.30.30.100 1 75 1.4E-24 T 23-10-2018 A3L04_00005 94e945ded94b7caf3a3513294f07709a 307 Gene3D G3DSA:1.10.3720.10 91 298 5.1E-19 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_00005 94e945ded94b7caf3a3513294f07709a 307 SUPERFAMILY SSF161098 97 288 4.32E-21 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_00005 94e945ded94b7caf3a3513294f07709a 307 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 6 42 4.0E-6 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A3L04_00005 94e945ded94b7caf3a3513294f07709a 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 306 1.0E-27 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L04_06855 fb38a0eda46ccab6c10d6c9648dbb047 389 Gene3D G3DSA:1.20.1250.20 1 191 3.8E-38 T 23-10-2018 A3L04_06855 fb38a0eda46ccab6c10d6c9648dbb047 389 Gene3D G3DSA:1.20.1250.20 194 369 9.0E-24 T 23-10-2018 A3L04_06855 fb38a0eda46ccab6c10d6c9648dbb047 389 Pfam PF07690 Major Facilitator Superfamily 19 331 5.3E-43 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L04_06855 fb38a0eda46ccab6c10d6c9648dbb047 389 SUPERFAMILY SSF103473 3 370 8.24E-68 T 23-10-2018 IPR036259 MFS transporter superfamily A3L04_02040 905be150e017d66c7b4c29377e1156de 255 SMART SM00849 39 228 7.2E-25 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_02040 905be150e017d66c7b4c29377e1156de 255 Pfam PF00753 Metallo-beta-lactamase superfamily 38 228 1.4E-17 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_02040 905be150e017d66c7b4c29377e1156de 255 SUPERFAMILY SSF56281 34 244 1.06E-34 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_02040 905be150e017d66c7b4c29377e1156de 255 Gene3D G3DSA:3.60.15.10 6 246 8.9E-46 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_03920 d19c46c408d9f02799628d429d72fdc2 248 SUPERFAMILY SSF51366 6 243 1.13E-82 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L04_03920 d19c46c408d9f02799628d429d72fdc2 248 Pfam PF00290 Tryptophan synthase alpha chain 4 243 4.5E-81 T 23-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L04_03920 d19c46c408d9f02799628d429d72fdc2 248 Gene3D G3DSA:3.20.20.70 1 248 1.8E-99 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_03920 d19c46c408d9f02799628d429d72fdc2 248 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 2 248 36.577 T 23-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L04_03920 d19c46c408d9f02799628d429d72fdc2 248 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 35 48 - T 23-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L04_03920 d19c46c408d9f02799628d429d72fdc2 248 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 3 244 7.3E-88 T 23-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L04_02560 3eac2442165bb3a59fec2d7650d3526b 502 SUPERFAMILY SSF51395 97 494 1.03E-129 T 23-10-2018 A3L04_02560 3eac2442165bb3a59fec2d7650d3526b 502 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 49 60 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_02560 3eac2442165bb3a59fec2d7650d3526b 502 Gene3D G3DSA:3.30.70.20 3 40 4.5E-6 T 23-10-2018 A3L04_02560 3eac2442165bb3a59fec2d7650d3526b 502 Pfam PF01645 Conserved region in glutamate synthase 107 470 9.2E-145 T 23-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 A3L04_02560 3eac2442165bb3a59fec2d7650d3526b 502 Gene3D G3DSA:3.30.70.20 41 85 2.2E-5 T 23-10-2018 A3L04_02560 3eac2442165bb3a59fec2d7650d3526b 502 PIRSF PIRSF006429 2 502 4.2E-162 T 23-10-2018 IPR024188 Glutamate synthase large subunit-like protein A3L04_02560 3eac2442165bb3a59fec2d7650d3526b 502 Pfam PF13187 4Fe-4S dicluster domain 17 63 1.7E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L04_02560 3eac2442165bb3a59fec2d7650d3526b 502 Gene3D G3DSA:3.20.20.70 128 495 3.5E-139 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_02560 3eac2442165bb3a59fec2d7650d3526b 502 PIRSF PIRSF500061 1 502 1.2E-209 T 23-10-2018 A3L04_02560 3eac2442165bb3a59fec2d7650d3526b 502 SUPERFAMILY SSF54862 7 143 4.19E-21 T 23-10-2018 A3L04_05270 32d11aafb3fe9cdf0b2cef8a508f6538 101 Pfam PF03091 CutA1 divalent ion tolerance protein 2 98 8.4E-34 T 23-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 A3L04_05270 32d11aafb3fe9cdf0b2cef8a508f6538 101 Gene3D G3DSA:3.30.70.120 1 100 2.1E-38 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A3L04_05270 32d11aafb3fe9cdf0b2cef8a508f6538 101 SUPERFAMILY SSF54913 1 100 2.34E-35 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A3L04_09890 c7e9921457cc01e47b080c950818c5d4 96 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 25 82 2.6E-13 T 23-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A3L04_09890 c7e9921457cc01e47b080c950818c5d4 96 SUPERFAMILY SSF101386 1 79 1.57E-21 T 23-10-2018 A3L04_09890 c7e9921457cc01e47b080c950818c5d4 96 Gene3D G3DSA:1.10.287.1080 1 79 9.6E-28 T 23-10-2018 A3L04_05170 849b8fa423ef0013d38636e92f2c3570 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 295 1.6E-26 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L04_05170 849b8fa423ef0013d38636e92f2c3570 297 SUPERFAMILY SSF161098 81 271 7.59E-25 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_05170 849b8fa423ef0013d38636e92f2c3570 297 Gene3D G3DSA:1.10.3720.10 76 296 1.2E-21 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 SUPERFAMILY SSF52540 540 818 6.9E-83 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 118 199 6.6E-13 T 23-10-2018 IPR004201 CDC48, domain 2 A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 14 97 8.1E-30 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 SMART SM01072 116 199 1.1E-16 T 23-10-2018 IPR004201 CDC48, domain 2 A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 Gene3D G3DSA:3.40.50.300 205 377 1.3E-82 T 23-10-2018 A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 ProSitePatterns PS00674 AAA-protein family signature. 683 701 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 13 824 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 ProSitePatterns PS00674 AAA-protein family signature. 347 365 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 SUPERFAMILY SSF54585 98 212 3.92E-18 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 Gene3D G3DSA:1.10.8.60 435 533 8.6E-17 T 23-10-2018 A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 Gene3D G3DSA:1.10.8.60 378 408 1.3E-82 T 23-10-2018 A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 SUPERFAMILY SSF52540 205 531 8.37E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 SMART SM01073 14 98 2.4E-34 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 SMART SM00382 243 379 1.1E-25 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 SMART SM00382 578 715 1.0E-25 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 Gene3D G3DSA:2.40.40.20 7 98 3.5E-33 T 23-10-2018 A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 Gene3D G3DSA:1.10.8.60 714 822 7.4E-32 T 23-10-2018 A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 251 270 2.7E-5 T 23-10-2018 A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 651 670 2.7E-5 T 23-10-2018 A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 SUPERFAMILY SSF50692 9 96 4.72E-27 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 Gene3D G3DSA:3.40.50.300 534 713 8.5E-76 T 23-10-2018 A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 247 376 3.4E-51 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L04_05850 f21fb8355eae6dba872de0c431c45d8f 837 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 582 712 2.3E-48 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L04_03680 c2eab94b5ea5497efeafb129d373c951 251 Pfam PF00977 Histidine biosynthesis protein 5 233 1.3E-87 T 23-10-2018 IPR006062 Histidine biosynthesis GO:0000105 A3L04_03680 c2eab94b5ea5497efeafb129d373c951 251 Gene3D G3DSA:3.20.20.70 1 251 9.3E-108 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_03680 c2eab94b5ea5497efeafb129d373c951 251 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 2 249 1.4E-107 T 23-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A3L04_03680 c2eab94b5ea5497efeafb129d373c951 251 SUPERFAMILY SSF51366 2 249 2.51E-83 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L04_03680 c2eab94b5ea5497efeafb129d373c951 251 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 249 47.565 T 23-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A3L04_02440 09adee2926d2e7c037762f0e1dbdb55c 170 SUPERFAMILY SSF53032 79 168 2.09E-29 T 23-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A3L04_02440 09adee2926d2e7c037762f0e1dbdb55c 170 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 80 162 3.0E-31 T 23-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A3L04_02440 09adee2926d2e7c037762f0e1dbdb55c 170 Pfam PF02778 tRNA intron endonuclease, N-terminal domain 6 69 1.5E-19 T 23-10-2018 IPR006678 tRNA intron endonuclease, N-terminal GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A3L04_02440 09adee2926d2e7c037762f0e1dbdb55c 170 Gene3D G3DSA:3.40.1170.20 7 73 4.1E-15 T 23-10-2018 A3L04_02440 09adee2926d2e7c037762f0e1dbdb55c 170 Hamap MF_01833 tRNA-splicing endonuclease [endA]. 5 170 33.861 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 A3L04_02440 09adee2926d2e7c037762f0e1dbdb55c 170 PIRSF PIRSF005285 8 170 5.9E-65 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 A3L04_02440 09adee2926d2e7c037762f0e1dbdb55c 170 TIGRFAM TIGR00324 endA: tRNA-intron lyase 9 167 1.3E-38 T 23-10-2018 IPR006676 tRNA-splicing endonuclease GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A3L04_02440 09adee2926d2e7c037762f0e1dbdb55c 170 Gene3D G3DSA:3.40.1350.10 79 170 2.9E-32 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A3L04_02440 09adee2926d2e7c037762f0e1dbdb55c 170 SUPERFAMILY SSF55267 5 76 1.12E-18 T 23-10-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 A3L04_02230 bb21af9d526876c18b0a808a6b31de18 219 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 23-10-2018 A3L04_02230 bb21af9d526876c18b0a808a6b31de18 219 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 1 206 1.5E-55 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 A3L04_02230 bb21af9d526876c18b0a808a6b31de18 219 Gene3D G3DSA:1.10.150.520 16 87 1.8E-47 T 23-10-2018 A3L04_02230 bb21af9d526876c18b0a808a6b31de18 219 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 82 185 1.8E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_02230 bb21af9d526876c18b0a808a6b31de18 219 Gene3D G3DSA:3.40.50.1000 3 206 1.8E-47 T 23-10-2018 IPR023214 HAD superfamily A3L04_02230 bb21af9d526876c18b0a808a6b31de18 219 SUPERFAMILY SSF56784 1 210 1.31E-48 T 23-10-2018 IPR036412 HAD-like superfamily A3L04_02230 bb21af9d526876c18b0a808a6b31de18 219 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 185 1.6E-30 T 23-10-2018 A3L04_02230 bb21af9d526876c18b0a808a6b31de18 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 144 3.9E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_02230 bb21af9d526876c18b0a808a6b31de18 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 3.9E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_02230 bb21af9d526876c18b0a808a6b31de18 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 98 111 3.9E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_02230 bb21af9d526876c18b0a808a6b31de18 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 174 187 3.9E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_02230 bb21af9d526876c18b0a808a6b31de18 219 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 87 179 5.0E-13 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_07970 8412aaa098a05f23320506960161f95f 287 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_07970 8412aaa098a05f23320506960161f95f 287 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 263 1.8E-17 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L04_07970 8412aaa098a05f23320506960161f95f 287 Gene3D G3DSA:3.30.70.20 66 110 1.2E-8 T 23-10-2018 A3L04_07970 8412aaa098a05f23320506960161f95f 287 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 69 80 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_07970 8412aaa098a05f23320506960161f95f 287 SUPERFAMILY SSF52540 1 284 9.3E-32 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_07970 8412aaa098a05f23320506960161f95f 287 Pfam PF14697 4Fe-4S dicluster domain 64 116 2.1E-9 T 23-10-2018 A3L04_01795 eeb0a934f9a4b6608826b106f2ab49d2 317 Pfam PF08544 GHMP kinases C terminal 210 294 2.2E-4 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain A3L04_01795 eeb0a934f9a4b6608826b106f2ab49d2 317 SUPERFAMILY SSF54211 1 139 3.26E-13 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L04_01795 eeb0a934f9a4b6608826b106f2ab49d2 317 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 4 313 2.1E-41 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 A3L04_01795 eeb0a934f9a4b6608826b106f2ab49d2 317 Gene3D G3DSA:3.30.230.10 4 138 1.3E-5 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L04_01795 eeb0a934f9a4b6608826b106f2ab49d2 317 PIRSF PIRSF004884 1 316 1.0E-75 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 A3L04_02610 9672dabcb6d6f6520aa01d3884c6fab7 348 Gene3D G3DSA:3.40.50.2000 4 161 2.0E-6 T 23-10-2018 A3L04_02610 9672dabcb6d6f6520aa01d3884c6fab7 348 Gene3D G3DSA:3.40.50.2000 162 327 4.6E-16 T 23-10-2018 A3L04_02610 9672dabcb6d6f6520aa01d3884c6fab7 348 SUPERFAMILY SSF53756 39 346 1.44E-33 T 23-10-2018 A3L04_02610 9672dabcb6d6f6520aa01d3884c6fab7 348 Pfam PF00534 Glycosyl transferases group 1 159 286 3.0E-11 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L04_08590 ddfac1872b1a404899f5167944ad42f8 288 Pfam PF00175 Oxidoreductase NAD-binding domain 113 226 1.4E-12 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A3L04_08590 ddfac1872b1a404899f5167944ad42f8 288 PRINTS PR00410 Phenol hydroxylase reductase family signature 213 221 1.1E-11 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L04_08590 ddfac1872b1a404899f5167944ad42f8 288 PRINTS PR00410 Phenol hydroxylase reductase family signature 137 146 1.1E-11 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L04_08590 ddfac1872b1a404899f5167944ad42f8 288 PRINTS PR00410 Phenol hydroxylase reductase family signature 39 51 1.1E-11 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L04_08590 ddfac1872b1a404899f5167944ad42f8 288 PRINTS PR00410 Phenol hydroxylase reductase family signature 112 131 1.1E-11 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L04_08590 ddfac1872b1a404899f5167944ad42f8 288 SUPERFAMILY SSF63380 5 101 1.15E-19 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L04_08590 ddfac1872b1a404899f5167944ad42f8 288 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 245 279 1.6E-13 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L04_08590 ddfac1872b1a404899f5167944ad42f8 288 SUPERFAMILY SSF52343 96 279 5.37E-32 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L04_08590 ddfac1872b1a404899f5167944ad42f8 288 Gene3D G3DSA:2.40.30.10 2 100 2.9E-18 T 23-10-2018 A3L04_08590 ddfac1872b1a404899f5167944ad42f8 288 PIRSF PIRSF006816 3 288 3.2E-82 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L04_08590 ddfac1872b1a404899f5167944ad42f8 288 Gene3D G3DSA:3.40.50.80 103 245 8.2E-24 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L04_08590 ddfac1872b1a404899f5167944ad42f8 288 Gene3D G3DSA:2.10.240.10 246 280 9.6E-9 T 23-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily A3L04_09210 bd3fedd92982c8dee62d00d575c4d8f4 112 SUPERFAMILY SSF88659 46 93 4.3E-9 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A3L04_09210 bd3fedd92982c8dee62d00d575c4d8f4 112 Hamap MF_00674 UPF0251 protein . 12 109 23.459 T 23-10-2018 IPR002852 Uncharacterised protein family UPF0251 A3L04_09210 bd3fedd92982c8dee62d00d575c4d8f4 112 Pfam PF02001 Protein of unknown function DUF134 11 100 7.5E-27 T 23-10-2018 IPR002852 Uncharacterised protein family UPF0251 A3L04_09210 bd3fedd92982c8dee62d00d575c4d8f4 112 Gene3D G3DSA:1.10.10.10 45 94 8.1E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_06720 d15608f00f19fd58e4dc9cb96e5ffe64 866 Gene3D G3DSA:3.40.50.300 258 418 2.9E-26 T 23-10-2018 A3L04_06720 d15608f00f19fd58e4dc9cb96e5ffe64 866 PIRSF PIRSF037307 5 864 1.2E-296 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 A3L04_06720 d15608f00f19fd58e4dc9cb96e5ffe64 866 Pfam PF08494 DEAD/H associated 639 827 3.0E-57 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 A3L04_06720 d15608f00f19fd58e4dc9cb96e5ffe64 866 SUPERFAMILY SSF52540 47 386 1.67E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_06720 d15608f00f19fd58e4dc9cb96e5ffe64 866 SMART SM00382 48 368 0.0078 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_06720 d15608f00f19fd58e4dc9cb96e5ffe64 866 Gene3D G3DSA:3.40.50.300 13 235 1.6E-54 T 23-10-2018 A3L04_06720 d15608f00f19fd58e4dc9cb96e5ffe64 866 SMART SM00487 31 245 5.8E-31 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L04_06720 d15608f00f19fd58e4dc9cb96e5ffe64 866 SMART SM00490 303 385 1.7E-20 T 23-10-2018 IPR001650 Helicase, C-terminal A3L04_06720 d15608f00f19fd58e4dc9cb96e5ffe64 866 Pfam PF00270 DEAD/DEAH box helicase 36 220 1.4E-27 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L04_06720 d15608f00f19fd58e4dc9cb96e5ffe64 866 Pfam PF00271 Helicase conserved C-terminal domain 274 381 1.7E-18 T 23-10-2018 IPR001650 Helicase, C-terminal A3L04_04395 27ca197a8a1526b00bd17a4d13247e2f 341 Gene3D G3DSA:3.20.20.120 201 339 5.8E-9 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A3L04_04395 27ca197a8a1526b00bd17a4d13247e2f 341 SMART SM01193 4 119 3.1E-33 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_04395 27ca197a8a1526b00bd17a4d13247e2f 341 SUPERFAMILY SSF51604 126 337 1.09E-29 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A3L04_04395 27ca197a8a1526b00bd17a4d13247e2f 341 SMART SM01192 124 340 1.4E-11 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_04395 27ca197a8a1526b00bd17a4d13247e2f 341 PRINTS PR00148 Enolase signature 316 330 1.2E-5 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_04395 27ca197a8a1526b00bd17a4d13247e2f 341 PRINTS PR00148 Enolase signature 92 108 1.2E-5 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_04395 27ca197a8a1526b00bd17a4d13247e2f 341 Gene3D G3DSA:3.30.390.10 1 111 1.4E-20 T 23-10-2018 IPR029017 Enolase-like, N-terminal A3L04_04395 27ca197a8a1526b00bd17a4d13247e2f 341 SUPERFAMILY SSF54826 4 125 5.3E-28 T 23-10-2018 A3L04_04395 27ca197a8a1526b00bd17a4d13247e2f 341 Pfam PF03952 Enolase, N-terminal domain 4 119 8.2E-21 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_03700 98ed8ce0960e89fb2089975f8141de9d 131 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 131 9.686 T 23-10-2018 IPR022907 VapC family GO:0004540 A3L04_03700 98ed8ce0960e89fb2089975f8141de9d 131 Gene3D G3DSA:3.40.50.1010 2 130 2.9E-19 T 23-10-2018 A3L04_03700 98ed8ce0960e89fb2089975f8141de9d 131 SMART SM00670 1 123 6.9E-11 T 23-10-2018 IPR002716 PIN domain A3L04_03700 98ed8ce0960e89fb2089975f8141de9d 131 Pfam PF01850 PIN domain 3 126 8.7E-23 T 23-10-2018 IPR002716 PIN domain A3L04_03700 98ed8ce0960e89fb2089975f8141de9d 131 SUPERFAMILY SSF88723 1 130 1.65E-26 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_00290 5a0ca7545583224c69c00e6214ad31f1 492 SUPERFAMILY SSF53067 246 484 2.23E-83 T 23-10-2018 A3L04_00290 5a0ca7545583224c69c00e6214ad31f1 492 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 484 5.2E-216 T 23-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A3L04_00290 5a0ca7545583224c69c00e6214ad31f1 492 PIRSF PIRSF000538 1 489 1.2E-175 T 23-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A3L04_00290 5a0ca7545583224c69c00e6214ad31f1 492 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 352 372 - T 23-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A3L04_00290 5a0ca7545583224c69c00e6214ad31f1 492 Gene3D G3DSA:3.30.420.40 1 244 1.0E-109 T 23-10-2018 A3L04_00290 5a0ca7545583224c69c00e6214ad31f1 492 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 253 438 6.1E-55 T 23-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A3L04_00290 5a0ca7545583224c69c00e6214ad31f1 492 Gene3D G3DSA:3.30.420.40 245 491 1.5E-95 T 23-10-2018 A3L04_00290 5a0ca7545583224c69c00e6214ad31f1 492 SUPERFAMILY SSF53067 3 245 9.07E-95 T 23-10-2018 A3L04_00290 5a0ca7545583224c69c00e6214ad31f1 492 Hamap MF_00186 Glycerol kinase [glpK]. 1 485 57.352 T 23-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A3L04_00290 5a0ca7545583224c69c00e6214ad31f1 492 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 131 143 - T 23-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A3L04_00290 5a0ca7545583224c69c00e6214ad31f1 492 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 243 1.2E-84 T 23-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A3L04_08805 a17f1029c18247c8db1f0f1e9627b71d 358 Gene3D G3DSA:3.20.20.70 38 220 4.6E-9 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_08805 a17f1029c18247c8db1f0f1e9627b71d 358 SUPERFAMILY SSF102114 39 211 1.57E-14 T 23-10-2018 A3L04_08805 a17f1029c18247c8db1f0f1e9627b71d 358 PIRSF PIRSF018654 4 358 4.6E-174 T 23-10-2018 IPR014494 Predicted Fe-S oxidoreductase, NifB/MoaA-like family, euryarchaeota type A3L04_08805 a17f1029c18247c8db1f0f1e9627b71d 358 Pfam PF04459 Protein of unknown function (DUF512) 249 332 1.5E-11 T 23-10-2018 IPR007549 Domain of unknown function DUF512 A3L04_03735 0f820b47f3862cbab61cb4f04a455aad 199 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 104 110 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A3L04_03735 0f820b47f3862cbab61cb4f04a455aad 199 Pfam PF05175 Methyltransferase small domain 23 173 5.9E-19 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A3L04_03735 0f820b47f3862cbab61cb4f04a455aad 199 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 16 194 3.0E-50 T 23-10-2018 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 A3L04_03735 0f820b47f3862cbab61cb4f04a455aad 199 Gene3D G3DSA:3.40.50.150 14 198 4.5E-43 T 23-10-2018 A3L04_03735 0f820b47f3862cbab61cb4f04a455aad 199 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 134 158 9.9E-5 T 23-10-2018 A3L04_03735 0f820b47f3862cbab61cb4f04a455aad 199 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 40 54 9.9E-5 T 23-10-2018 A3L04_03735 0f820b47f3862cbab61cb4f04a455aad 199 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 101 113 9.9E-5 T 23-10-2018 A3L04_03735 0f820b47f3862cbab61cb4f04a455aad 199 SUPERFAMILY SSF53335 3 183 4.26E-38 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_04695 d5397a666619ed12f2f219dd06154360 222 TIGRFAM TIGR03665 arCOG04150: arCOG04150 universal archaeal KH domain protein 40 214 1.4E-70 T 23-10-2018 IPR019964 KH domain protein, archaea A3L04_04695 d5397a666619ed12f2f219dd06154360 222 SUPERFAMILY SSF54791 123 204 4.24E-18 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L04_04695 d5397a666619ed12f2f219dd06154360 222 Gene3D G3DSA:3.30.1370.10 34 117 3.8E-36 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L04_04695 d5397a666619ed12f2f219dd06154360 222 Pfam PF00013 KH domain 142 189 3.7E-6 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A3L04_04695 d5397a666619ed12f2f219dd06154360 222 Pfam PF00013 KH domain 40 86 6.2E-9 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A3L04_04695 d5397a666619ed12f2f219dd06154360 222 SUPERFAMILY SSF54791 32 114 5.94E-14 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L04_04695 d5397a666619ed12f2f219dd06154360 222 Gene3D G3DSA:3.30.1370.10 118 221 8.9E-34 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L04_04695 d5397a666619ed12f2f219dd06154360 222 SMART SM00322 35 105 5.3E-12 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L04_04695 d5397a666619ed12f2f219dd06154360 222 SMART SM00322 119 193 3.0E-6 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L04_01285 e4de80d7384eca3c75baefe1d489de4b 133 Gene3D G3DSA:3.10.180.10 1 132 1.5E-43 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A3L04_01285 e4de80d7384eca3c75baefe1d489de4b 133 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 115 6.0E-26 T 23-10-2018 A3L04_01285 e4de80d7384eca3c75baefe1d489de4b 133 SUPERFAMILY SSF54593 1 132 1.13E-35 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A3L04_01285 e4de80d7384eca3c75baefe1d489de4b 133 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 130 6.5E-54 T 23-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 A3L04_02940 b5c90e91e59edcb670ac8446ea5d5311 321 Pfam PF00005 ABC transporter 24 179 1.9E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_02940 b5c90e91e59edcb670ac8446ea5d5311 321 SUPERFAMILY SSF52540 3 261 8.05E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_02940 b5c90e91e59edcb670ac8446ea5d5311 321 Gene3D G3DSA:3.40.50.300 1 320 6.8E-86 T 23-10-2018 A3L04_02940 b5c90e91e59edcb670ac8446ea5d5311 321 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_02940 b5c90e91e59edcb670ac8446ea5d5311 321 SMART SM00382 32 237 6.5E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_02940 b5c90e91e59edcb670ac8446ea5d5311 321 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 229 317 8.4E-27 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L04_02940 b5c90e91e59edcb670ac8446ea5d5311 321 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 297 4.3E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L04_00920 0a67f0eb7b2fc68421897679511fe466 359 Pfam PF03576 Peptidase family S58 19 340 2.9E-119 T 23-10-2018 IPR005321 Peptidase S58, DmpA A3L04_00920 0a67f0eb7b2fc68421897679511fe466 359 Gene3D G3DSA:3.60.70.12 1 359 3.8E-162 T 23-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A3L04_00920 0a67f0eb7b2fc68421897679511fe466 359 SUPERFAMILY SSF56266 2 358 2.62E-114 T 23-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A3L04_03985 2a6b75e8ea987519b256a7c42deec2da 338 Gene3D G3DSA:3.20.20.70 1 338 3.2E-136 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_03985 2a6b75e8ea987519b256a7c42deec2da 338 SUPERFAMILY SSF102114 73 296 1.59E-16 T 23-10-2018 A3L04_03985 2a6b75e8ea987519b256a7c42deec2da 338 Pfam PF04055 Radical SAM superfamily 72 257 4.1E-23 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_03985 2a6b75e8ea987519b256a7c42deec2da 338 Pfam PF08608 Wyosine base formation 259 320 9.5E-23 T 23-10-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 A3L04_03985 2a6b75e8ea987519b256a7c42deec2da 338 Hamap MF_01921 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase [taw1]. 20 321 50.108 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 A3L04_03985 2a6b75e8ea987519b256a7c42deec2da 338 TIGRFAM TIGR03972 rSAM_TYW1: wyosine biosynthesis protein TYW1 22 319 6.6E-132 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 A3L04_01290 81ffd50bf477c8afdc4bd79d5d3195c4 315 Pfam PF03308 ArgK protein 18 282 7.4E-99 T 23-10-2018 A3L04_01290 81ffd50bf477c8afdc4bd79d5d3195c4 315 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 12 311 5.4E-130 T 23-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L04_01290 81ffd50bf477c8afdc4bd79d5d3195c4 315 SUPERFAMILY SSF52540 2 309 1.57E-80 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01290 81ffd50bf477c8afdc4bd79d5d3195c4 315 SMART SM00382 44 194 7.0E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_01290 81ffd50bf477c8afdc4bd79d5d3195c4 315 Gene3D G3DSA:3.40.50.300 43 252 2.2E-87 T 23-10-2018 A3L04_01290 81ffd50bf477c8afdc4bd79d5d3195c4 315 Gene3D G3DSA:1.20.5.170 1 42 1.8E-6 T 23-10-2018 A3L04_00150 9858baf4c5752ad897712c04d78b94b7 206 TIGRFAM TIGR01491 HAD-SF-IB-PSPlk: phosphoserine phosphatase-like hydrolase, archaeal 1 183 1.8E-73 T 23-10-2018 IPR006386 HAD-superfamily hydrolase, subfamily IB, PSPase-like, archaeal A3L04_00150 9858baf4c5752ad897712c04d78b94b7 206 SUPERFAMILY SSF56784 1 200 9.74E-40 T 23-10-2018 IPR036412 HAD-like superfamily A3L04_00150 9858baf4c5752ad897712c04d78b94b7 206 Pfam PF12710 haloacid dehalogenase-like hydrolase 4 170 3.2E-19 T 23-10-2018 A3L04_00150 9858baf4c5752ad897712c04d78b94b7 206 Gene3D G3DSA:1.10.150.210 13 73 8.5E-50 T 23-10-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 A3L04_00150 9858baf4c5752ad897712c04d78b94b7 206 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 3 171 1.5E-43 T 23-10-2018 A3L04_00150 9858baf4c5752ad897712c04d78b94b7 206 Gene3D G3DSA:3.40.50.1000 2 180 8.5E-50 T 23-10-2018 IPR023214 HAD superfamily A3L04_09215 ec2be0b118bfe7da011df55343e3808a 290 Gene3D G3DSA:1.10.10.10 204 277 3.2E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_09215 ec2be0b118bfe7da011df55343e3808a 290 SUPERFAMILY SSF46785 213 275 3.27E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_03245 c8b12fd900c83119a790b9f650c5201c 441 Gene3D G3DSA:1.10.8.60 355 439 1.4E-27 T 23-10-2018 A3L04_03245 c8b12fd900c83119a790b9f650c5201c 441 SUPERFAMILY SSF50249 126 207 2.74E-19 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_03245 c8b12fd900c83119a790b9f650c5201c 441 Pfam PF06068 TIP49 C-terminus 14 404 2.6E-163 T 23-10-2018 IPR010339 TIP49, C-terminal GO:0003678|GO:0005524 Reactome: R-HSA-171319|Reactome: R-HSA-3214847 A3L04_03245 c8b12fd900c83119a790b9f650c5201c 441 SMART SM00382 62 354 2.4E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_03245 c8b12fd900c83119a790b9f650c5201c 441 SUPERFAMILY SSF52540 37 424 5.4E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_03245 c8b12fd900c83119a790b9f650c5201c 441 Gene3D G3DSA:2.40.50.360 119 243 9.6E-112 T 23-10-2018 A3L04_03245 c8b12fd900c83119a790b9f650c5201c 441 Gene3D G3DSA:3.40.50.300 18 350 9.6E-112 T 23-10-2018 A3L04_05450 5543b2b308e103474260e321f4e5c304 320 Gene3D G3DSA:3.40.50.720 6 310 4.6E-101 T 23-10-2018 A3L04_05450 5543b2b308e103474260e321f4e5c304 320 PIRSF PIRSF036497 1 319 1.6E-85 T 23-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A3L04_05450 5543b2b308e103474260e321f4e5c304 320 Gene3D G3DSA:3.30.360.10 160 293 4.6E-101 T 23-10-2018 A3L04_05450 5543b2b308e103474260e321f4e5c304 320 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 141 1.2E-11 T 23-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 A3L04_05450 5543b2b308e103474260e321f4e5c304 320 SUPERFAMILY SSF55347 149 297 1.5E-30 T 23-10-2018 A3L04_05450 5543b2b308e103474260e321f4e5c304 320 SUPERFAMILY SSF51735 1 170 5.78E-28 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_05450 5543b2b308e103474260e321f4e5c304 320 Pfam PF00742 Homoserine dehydrogenase 149 310 1.0E-36 T 23-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A3L04_04505 306d421f4448be185820d0f299e978ca 249 SMART SM00849 37 215 5.4E-13 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_04505 306d421f4448be185820d0f299e978ca 249 Gene3D G3DSA:3.60.15.10 1 249 9.4E-49 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_04505 306d421f4448be185820d0f299e978ca 249 SUPERFAMILY SSF56281 1 247 3.54E-40 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_04505 306d421f4448be185820d0f299e978ca 249 Pfam PF12706 Beta-lactamase superfamily domain 50 216 1.2E-18 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_06695 fd5e51e5efb4cf4f14bc4ac4c7a33675 583 SMART SM00359 508 582 4.7E-18 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L04_06695 fd5e51e5efb4cf4f14bc4ac4c7a33675 583 SUPERFAMILY SSF88802 361 505 1.18E-45 T 23-10-2018 A3L04_06695 fd5e51e5efb4cf4f14bc4ac4c7a33675 583 Gene3D G3DSA:3.90.1020.10 361 430 5.4E-31 T 23-10-2018 IPR038370 TGT, C1 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L04_06695 fd5e51e5efb4cf4f14bc4ac4c7a33675 583 Gene3D G3DSA:3.10.450.90 431 504 2.9E-30 T 23-10-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L04_06695 fd5e51e5efb4cf4f14bc4ac4c7a33675 583 SUPERFAMILY SSF51713 6 359 2.09E-117 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L04_06695 fd5e51e5efb4cf4f14bc4ac4c7a33675 583 Pfam PF14809 C1 domain of tRNA-guanine transglycosylase dimerisation 361 430 8.9E-41 T 23-10-2018 IPR032729 tRNA-guanine(15) transglycosylase, C1 domain MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L04_06695 fd5e51e5efb4cf4f14bc4ac4c7a33675 583 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 438 506 6.8E-23 T 23-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L04_06695 fd5e51e5efb4cf4f14bc4ac4c7a33675 583 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 489 578 8.0E-9 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L04_06695 fd5e51e5efb4cf4f14bc4ac4c7a33675 583 TIGRFAM TIGR00432 arcsn_tRNA_tgt: tRNA-guanine(15) transglycosylase 10 392 1.4E-169 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L04_06695 fd5e51e5efb4cf4f14bc4ac4c7a33675 583 Gene3D G3DSA:2.30.130.10 505 582 5.6E-33 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L04_06695 fd5e51e5efb4cf4f14bc4ac4c7a33675 583 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 10 341 9.7E-88 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L04_06695 fd5e51e5efb4cf4f14bc4ac4c7a33675 583 SUPERFAMILY SSF88697 507 581 3.31E-20 T 23-10-2018 IPR015947 PUA-like superfamily A3L04_06695 fd5e51e5efb4cf4f14bc4ac4c7a33675 583 Pfam PF01472 PUA domain 509 579 3.9E-12 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L04_06695 fd5e51e5efb4cf4f14bc4ac4c7a33675 583 Pfam PF01702 Queuine tRNA-ribosyltransferase 113 334 1.1E-40 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L04_06695 fd5e51e5efb4cf4f14bc4ac4c7a33675 583 Gene3D G3DSA:3.20.20.105 1 360 1.2E-126 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L04_06695 fd5e51e5efb4cf4f14bc4ac4c7a33675 583 Hamap MF_01634 tRNA-guanine(15) transglycosylase [tgtA]. 10 534 48.229 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L04_08110 bb69ff353d23afa0529d1f06336a3e2e 100 Gene3D G3DSA:1.20.1260.10 4 74 1.7E-10 T 23-10-2018 IPR012347 Ferritin-like A3L04_08110 bb69ff353d23afa0529d1f06336a3e2e 100 SUPERFAMILY SSF47240 6 85 4.88E-20 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L04_08110 bb69ff353d23afa0529d1f06336a3e2e 100 Pfam PF02915 Rubrerythrin 24 89 7.4E-8 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L04_10105 7dd7abec1f3fe23629f28cf1f1f5d75f 336 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 2 336 3.2E-121 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A3L04_10105 7dd7abec1f3fe23629f28cf1f1f5d75f 336 SUPERFAMILY SSF56042 155 330 3.59E-46 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L04_10105 7dd7abec1f3fe23629f28cf1f1f5d75f 336 Gene3D G3DSA:3.90.650.10 154 336 1.2E-55 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L04_10105 7dd7abec1f3fe23629f28cf1f1f5d75f 336 Pfam PF00586 AIR synthase related protein, N-terminal domain 40 149 2.0E-17 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L04_10105 7dd7abec1f3fe23629f28cf1f1f5d75f 336 Gene3D G3DSA:3.30.1330.10 1 153 3.9E-44 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L04_10105 7dd7abec1f3fe23629f28cf1f1f5d75f 336 PIRSF PIRSF005644 1 336 1.1E-127 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A3L04_10105 7dd7abec1f3fe23629f28cf1f1f5d75f 336 Pfam PF02769 AIR synthase related protein, C-terminal domain 160 313 3.7E-31 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L04_10105 7dd7abec1f3fe23629f28cf1f1f5d75f 336 SUPERFAMILY SSF55326 2 153 1.92E-33 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L04_09800 be70e74f7e665e8a01fd916000027413 681 SUPERFAMILY SSF56712 1 617 1.96E-161 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain A3L04_09800 be70e74f7e665e8a01fd916000027413 681 SMART SM00436 130 225 1.5E-43 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A3L04_09800 be70e74f7e665e8a01fd916000027413 681 SMART SM00437 270 526 2.3E-107 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A3L04_09800 be70e74f7e665e8a01fd916000027413 681 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 391 407 1.8E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L04_09800 be70e74f7e665e8a01fd916000027413 681 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 490 504 1.8E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L04_09800 be70e74f7e665e8a01fd916000027413 681 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 102 115 1.8E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L04_09800 be70e74f7e665e8a01fd916000027413 681 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 195 213 1.8E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L04_09800 be70e74f7e665e8a01fd916000027413 681 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 312 321 1.8E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L04_09800 be70e74f7e665e8a01fd916000027413 681 Pfam PF01131 DNA topoisomerase 155 563 8.6E-131 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L04_09800 be70e74f7e665e8a01fd916000027413 681 Gene3D G3DSA:3.40.50.140 1 153 5.7E-26 T 23-10-2018 A3L04_09800 be70e74f7e665e8a01fd916000027413 681 Pfam PF01751 Toprim domain 3 138 9.0E-17 T 23-10-2018 IPR006171 TOPRIM domain A3L04_09800 be70e74f7e665e8a01fd916000027413 681 SMART SM00493 1 128 1.7E-23 T 23-10-2018 IPR006171 TOPRIM domain A3L04_09800 be70e74f7e665e8a01fd916000027413 681 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 604 642 2.1E-13 T 23-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A3L04_09800 be70e74f7e665e8a01fd916000027413 681 Gene3D G3DSA:2.70.20.10 219 474 1.4E-122 T 23-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 A3L04_09800 be70e74f7e665e8a01fd916000027413 681 TIGRFAM TIGR01057 topA_arch: DNA topoisomerase I 5 635 0.0 T 23-10-2018 IPR005739 DNA topoisomerase I, archeal-type GO:0003677|GO:0003916|GO:0006265 A3L04_09800 be70e74f7e665e8a01fd916000027413 681 Hamap MF_00952 DNA topoisomerase 1 [topA]. 1 674 50.546 T 23-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 A3L04_09800 be70e74f7e665e8a01fd916000027413 681 Gene3D G3DSA:1.10.460.10 164 574 1.4E-122 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A3L04_09800 be70e74f7e665e8a01fd916000027413 681 Gene3D G3DSA:1.10.290.10 278 405 1.4E-122 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 A3L04_09800 be70e74f7e665e8a01fd916000027413 681 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 307 321 - T 23-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 A3L04_10460 f1117caff7d514f617149d5630919276 148 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 5 122 6.2E-28 T 23-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component A3L04_10460 f1117caff7d514f617149d5630919276 148 SUPERFAMILY SSF88723 1 123 3.08E-10 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_10460 f1117caff7d514f617149d5630919276 148 Pfam PF13470 PIN domain 5 117 4.3E-20 T 23-10-2018 IPR002716 PIN domain A3L04_10460 f1117caff7d514f617149d5630919276 148 SMART SM00670 4 121 3.9E-5 T 23-10-2018 IPR002716 PIN domain A3L04_02360 2774d1bae707d4b677c260ca062367cf 99 Gene3D G3DSA:3.30.70.330 1 99 1.4E-41 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily A3L04_02360 2774d1bae707d4b677c260ca062367cf 99 SUPERFAMILY SSF54189 1 97 9.71E-32 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_02360 2774d1bae707d4b677c260ca062367cf 99 ProDom PD006052 RIBOSOMAL S24 40S RIBONUCLEOPROTEIN S24E 30S S24 CDNA RIKEN ACETYLATION 11 57 2.0E-21 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_02360 2774d1bae707d4b677c260ca062367cf 99 ProSitePatterns PS00529 Ribosomal protein S24e signature. 60 82 - T 23-10-2018 IPR018098 Ribosomal S24e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_02360 2774d1bae707d4b677c260ca062367cf 99 Pfam PF01282 Ribosomal protein S24e 21 97 1.2E-26 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_02360 2774d1bae707d4b677c260ca062367cf 99 Hamap MF_00545 30S ribosomal protein S24e [rps24e]. 1 99 21.483 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_09040 96bfc84c2a2ce96d00c372a9f90e86db 362 TIGRFAM TIGR02585 cas_Cst2_DevR: CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP 16 353 8.7E-80 T 23-10-2018 IPR013414 CRISPR-associated protein Cas7, subtype I-B/Tneap A3L04_09040 96bfc84c2a2ce96d00c372a9f90e86db 362 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 30 268 1.7E-38 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR A3L04_09040 96bfc84c2a2ce96d00c372a9f90e86db 362 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 15 255 7.5E-15 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR A3L04_10115 48a24ffe77b9b0696e59c451d1092532 336 Pfam PF01916 Deoxyhypusine synthase 34 331 2.5E-113 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 A3L04_10115 48a24ffe77b9b0696e59c451d1092532 336 Hamap MF_00153 Probable deoxyhypusine synthase [dys]. 31 334 42.772 T 23-10-2018 IPR022899 Deoxyhypusine synthase, putative, archaeal GO:0034038 A3L04_10115 48a24ffe77b9b0696e59c451d1092532 336 Gene3D G3DSA:3.40.910.10 3 336 4.0E-147 T 23-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 A3L04_10115 48a24ffe77b9b0696e59c451d1092532 336 SUPERFAMILY SSF52467 4 334 3.92E-118 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A3L04_10115 48a24ffe77b9b0696e59c451d1092532 336 TIGRFAM TIGR00321 dhys: deoxyhypusine synthase 20 334 3.2E-123 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 A3L04_10815 b94caddd65389aae5178e58d10260a7b 319 SUPERFAMILY SSF46785 8 94 1.07E-22 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_10815 b94caddd65389aae5178e58d10260a7b 319 SUPERFAMILY SSF56112 102 273 7.69E-25 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A3L04_10815 b94caddd65389aae5178e58d10260a7b 319 SMART SM00090 68 299 5.8E-101 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A3L04_10815 b94caddd65389aae5178e58d10260a7b 319 Pfam PF01163 RIO1 family 111 291 1.3E-50 T 23-10-2018 A3L04_10815 b94caddd65389aae5178e58d10260a7b 319 Pfam PF09202 Rio2, N-terminal 13 93 2.3E-23 T 23-10-2018 IPR015285 RIO2 kinase winged helix domain, N-terminal GO:0004674|GO:0005524|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A3L04_10815 b94caddd65389aae5178e58d10260a7b 319 Gene3D G3DSA:3.30.200.20 98 195 1.6E-24 T 23-10-2018 A3L04_10815 b94caddd65389aae5178e58d10260a7b 319 Gene3D G3DSA:1.10.510.10 203 299 2.1E-17 T 23-10-2018 A3L04_10815 b94caddd65389aae5178e58d10260a7b 319 Gene3D G3DSA:1.10.10.10 5 94 1.6E-16 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_05360 c38d987616ec5a63934fc1512e9b2520 842 Pfam PF04851 Type III restriction enzyme, res subunit 153 307 5.3E-39 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A3L04_05360 c38d987616ec5a63934fc1512e9b2520 842 Gene3D G3DSA:3.90.1570.30 1 134 1.0E-41 T 23-10-2018 A3L04_05360 c38d987616ec5a63934fc1512e9b2520 842 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 3 120 1.7E-8 T 23-10-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain A3L04_05360 c38d987616ec5a63934fc1512e9b2520 842 SMART SM00487 150 342 1.6E-23 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L04_05360 c38d987616ec5a63934fc1512e9b2520 842 Gene3D G3DSA:3.40.50.300 135 323 1.2E-67 T 23-10-2018 A3L04_05360 c38d987616ec5a63934fc1512e9b2520 842 Pfam PF00271 Helicase conserved C-terminal domain 398 513 3.4E-9 T 23-10-2018 IPR001650 Helicase, C-terminal A3L04_05360 c38d987616ec5a63934fc1512e9b2520 842 Gene3D G3DSA:3.40.50.300 324 543 3.1E-49 T 23-10-2018 A3L04_05360 c38d987616ec5a63934fc1512e9b2520 842 Pfam PF08463 EcoEI R protein C-terminal 673 828 3.3E-12 T 23-10-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 A3L04_05360 c38d987616ec5a63934fc1512e9b2520 842 SUPERFAMILY SSF52540 166 522 5.6E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_08015 9fecd1a6a8cd6400fdcb8b3c860abcb9 464 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 60 112 1.7E-6 T 23-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_08015 9fecd1a6a8cd6400fdcb8b3c860abcb9 464 Pfam PF00361 Proton-conducting membrane transporter 128 406 4.8E-40 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_08015 9fecd1a6a8cd6400fdcb8b3c860abcb9 464 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 105 125 9.6E-27 T 23-10-2018 A3L04_08015 9fecd1a6a8cd6400fdcb8b3c860abcb9 464 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 70 95 9.6E-27 T 23-10-2018 A3L04_08015 9fecd1a6a8cd6400fdcb8b3c860abcb9 464 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 213 234 9.6E-27 T 23-10-2018 A3L04_08015 9fecd1a6a8cd6400fdcb8b3c860abcb9 464 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 151 172 9.6E-27 T 23-10-2018 A3L04_08015 9fecd1a6a8cd6400fdcb8b3c860abcb9 464 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 235 261 9.6E-27 T 23-10-2018 A3L04_07265 628c09c2e5d58f2fef04037c68c31ada 150 Hamap MF_01474 30S ribosomal protein S19e [rps19e]. 1 148 38.299 T 23-10-2018 IPR027548 Ribosomal protein S19e, archaeal GO:0003735|GO:0005840|GO:0006412 A3L04_07265 628c09c2e5d58f2fef04037c68c31ada 150 ProDom PD003854 RIBOSOMAL 40S RIBONUCLEOPROTEIN S19 S19E 30S MULTIGENE FAMILY S19 SSU 3 115 9.0E-60 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_07265 628c09c2e5d58f2fef04037c68c31ada 150 Gene3D G3DSA:1.10.10.2700 1 150 5.6E-66 T 23-10-2018 IPR038111 Ribosomal protein S19e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_07265 628c09c2e5d58f2fef04037c68c31ada 150 SMART SM01413 3 139 3.1E-91 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_07265 628c09c2e5d58f2fef04037c68c31ada 150 Pfam PF01090 Ribosomal protein S19e 3 138 8.4E-58 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_07265 628c09c2e5d58f2fef04037c68c31ada 150 ProSitePatterns PS00628 Ribosomal protein S19e signature. 87 106 - T 23-10-2018 IPR018277 Ribosomal protein S19e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_07265 628c09c2e5d58f2fef04037c68c31ada 150 SUPERFAMILY SSF46785 3 150 6.3E-61 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_09310 ea04e089493709271359277c42ff1f46 522 Gene3D G3DSA:3.90.226.10 1 260 1.8E-97 T 23-10-2018 A3L04_09310 ea04e089493709271359277c42ff1f46 522 Pfam PF01039 Carboxyl transferase domain 28 520 5.2E-203 T 23-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A3L04_09310 ea04e089493709271359277c42ff1f46 522 SUPERFAMILY SSF52096 3 257 1.13E-78 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L04_09310 ea04e089493709271359277c42ff1f46 522 SUPERFAMILY SSF52096 244 522 3.55E-94 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L04_09310 ea04e089493709271359277c42ff1f46 522 TIGRFAM TIGR01117 mmdA: methylmalonyl-CoA decarboxylase alpha subunit 5 522 0.0 T 23-10-2018 IPR005783 Methylmalonyl-CoA decarboxylase, alpha subunit A3L04_09310 ea04e089493709271359277c42ff1f46 522 Gene3D G3DSA:3.90.226.10 261 522 4.2E-96 T 23-10-2018 A3L04_03460 00e9c527306c1569b484fae3cb6cb9a1 184 Hamap MF_01365_A 50S ribosomal protein L6 [rplF]. 2 178 39.911 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 A3L04_03460 00e9c527306c1569b484fae3cb6cb9a1 184 Pfam PF00347 Ribosomal protein L6 13 85 7.6E-19 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03460 00e9c527306c1569b484fae3cb6cb9a1 184 Pfam PF00347 Ribosomal protein L6 97 171 8.0E-17 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03460 00e9c527306c1569b484fae3cb6cb9a1 184 SUPERFAMILY SSF56053 86 177 1.57E-31 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03460 00e9c527306c1569b484fae3cb6cb9a1 184 PIRSF PIRSF002162 5 182 1.7E-41 T 23-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03460 00e9c527306c1569b484fae3cb6cb9a1 184 ProSitePatterns PS00700 Ribosomal protein L6 signature 2. 156 177 - T 23-10-2018 IPR002359 Ribosomal protein L6, conserved site-2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03460 00e9c527306c1569b484fae3cb6cb9a1 184 SUPERFAMILY SSF56053 8 85 2.47E-23 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03460 00e9c527306c1569b484fae3cb6cb9a1 184 Gene3D G3DSA:3.90.930.12 6 85 2.3E-31 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03460 00e9c527306c1569b484fae3cb6cb9a1 184 Gene3D G3DSA:3.90.930.12 86 182 3.0E-39 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03460 00e9c527306c1569b484fae3cb6cb9a1 184 TIGRFAM TIGR03653 uL6_arch: ribosomal protein uL6 8 177 1.8E-80 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 A3L04_04770 df100645adf384c345cb77b6e5d24da7 276 Pfam PF01138 3' exoribonuclease family, domain 1 33 167 4.0E-29 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L04_04770 df100645adf384c345cb77b6e5d24da7 276 Gene3D G3DSA:3.30.230.70 1 273 6.7E-91 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L04_04770 df100645adf384c345cb77b6e5d24da7 276 Hamap MF_00622 Exosome complex component Rrp42 [rrp42]. 3 268 45.236 T 23-10-2018 IPR020869 Exosome complex component Rrp42, archaea GO:0000178|GO:0006401 A3L04_04770 df100645adf384c345cb77b6e5d24da7 276 SUPERFAMILY SSF55666 187 271 1.82E-25 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L04_04770 df100645adf384c345cb77b6e5d24da7 276 SUPERFAMILY SSF54211 12 215 3.54E-55 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L04_04770 df100645adf384c345cb77b6e5d24da7 276 Pfam PF03725 3' exoribonuclease family, domain 2 192 256 1.0E-14 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L04_01925 d973855ba2151050693183b269f54d04 204 Gene3D G3DSA:3.40.50.11570 1 203 1.5E-66 T 23-10-2018 A3L04_01925 d973855ba2151050693183b269f54d04 204 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 5 199 8.1E-50 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L04_06175 83b2cc12ff44824c3230c872d54f8e67 401 SUPERFAMILY SSF63882 6 180 1.44E-57 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L04_06175 83b2cc12ff44824c3230c872d54f8e67 401 SMART SM00852 184 321 5.1E-39 T 23-10-2018 IPR001453 MoaB/Mog domain A3L04_06175 83b2cc12ff44824c3230c872d54f8e67 401 SUPERFAMILY SSF63867 331 399 8.24E-20 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L04_06175 83b2cc12ff44824c3230c872d54f8e67 401 Gene3D G3DSA:3.90.105.10 26 178 5.5E-114 T 23-10-2018 A3L04_06175 83b2cc12ff44824c3230c872d54f8e67 401 Gene3D G3DSA:3.40.980.10 179 319 5.5E-114 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L04_06175 83b2cc12ff44824c3230c872d54f8e67 401 Pfam PF00994 Probable molybdopterin binding domain 184 319 1.5E-25 T 23-10-2018 IPR001453 MoaB/Mog domain A3L04_06175 83b2cc12ff44824c3230c872d54f8e67 401 SUPERFAMILY SSF53218 181 324 3.53E-42 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L04_06175 83b2cc12ff44824c3230c872d54f8e67 401 Gene3D G3DSA:2.170.190.11 49 145 5.5E-114 T 23-10-2018 A3L04_06175 83b2cc12ff44824c3230c872d54f8e67 401 Pfam PF03453 MoeA N-terminal region (domain I and II) 7 171 5.6E-43 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L04_06175 83b2cc12ff44824c3230c872d54f8e67 401 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 181 317 1.4E-34 T 23-10-2018 IPR001453 MoaB/Mog domain A3L04_06175 83b2cc12ff44824c3230c872d54f8e67 401 Gene3D G3DSA:2.40.340.10 329 400 1.7E-27 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L04_06175 83b2cc12ff44824c3230c872d54f8e67 401 Pfam PF03454 MoeA C-terminal region (domain IV) 333 399 1.1E-18 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L04_04525 a09bfb28e7f556481eeb8682e92bda6a 114 Gene3D G3DSA:1.20.5.420 1 60 1.6E-27 T 23-10-2018 A3L04_04525 a09bfb28e7f556481eeb8682e92bda6a 114 Gene3D G3DSA:2.20.25.200 61 114 6.9E-27 T 23-10-2018 A3L04_04525 a09bfb28e7f556481eeb8682e92bda6a 114 Pfam PF04032 RNAse P Rpr2/Rpp21/SNM1 subunit domain 18 97 7.2E-17 T 23-10-2018 IPR007175 RNAse P, Rpr2/Rpp21 subunit Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L04_04525 a09bfb28e7f556481eeb8682e92bda6a 114 PIRSF PIRSF004878 2 113 2.0E-44 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 A3L04_04525 a09bfb28e7f556481eeb8682e92bda6a 114 Hamap MF_00757 Ribonuclease P protein component 4 [rnp4]. 7 106 26.77 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 A3L04_03095 7172cdde20a4a6ad593a2c08cf15c1d9 107 SUPERFAMILY SSF111057 7 85 2.48E-28 T 23-10-2018 IPR036216 Hypothetical protein UCP004604 superfamily A3L04_03095 7172cdde20a4a6ad593a2c08cf15c1d9 107 Pfam PF08967 Domain of unknown function (DUF1884) 8 87 5.0E-26 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L04_03095 7172cdde20a4a6ad593a2c08cf15c1d9 107 PIRSF PIRSF004604 4 105 1.1E-41 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L04_03095 7172cdde20a4a6ad593a2c08cf15c1d9 107 ProDom PD029791 ORF 3'REGION GAP PF1875 PF0899 PH1831 B PHS036 17 82 1.0E-21 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L04_03095 7172cdde20a4a6ad593a2c08cf15c1d9 107 Gene3D G3DSA:3.30.2320.10 2 86 2.6E-26 T 23-10-2018 A3L04_06215 03e122c3079d49ae859d69bb2a56a091 250 SUPERFAMILY SSF52467 4 245 2.0E-92 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A3L04_06215 03e122c3079d49ae859d69bb2a56a091 250 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 13 247 64.044 T 23-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 A3L04_06215 03e122c3079d49ae859d69bb2a56a091 250 Pfam PF02146 Sir2 family 20 197 6.7E-59 T 23-10-2018 IPR003000 Sirtuin family GO:0070403 A3L04_06215 03e122c3079d49ae859d69bb2a56a091 250 Gene3D G3DSA:3.30.1600.10 29 167 7.9E-94 T 23-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily A3L04_06215 03e122c3079d49ae859d69bb2a56a091 250 Gene3D G3DSA:3.40.50.1220 11 241 7.9E-94 T 23-10-2018 A3L04_06775 f5e512b8c17c84af3e9ee43a40071604 1005 Gene3D G3DSA:3.20.110.10 260 527 2.0E-55 T 23-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily A3L04_06775 f5e512b8c17c84af3e9ee43a40071604 1005 SMART SM00872 526 604 2.7E-31 T 23-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 A3L04_06775 f5e512b8c17c84af3e9ee43a40071604 1005 Gene3D G3DSA:1.20.1270.50 529 625 2.3E-26 T 23-10-2018 IPR037094 Glycoside hydrolase family 38, central domain superfamily GO:0004559|GO:0006013 A3L04_06775 f5e512b8c17c84af3e9ee43a40071604 1005 Gene3D G3DSA:2.70.98.30 670 913 1.4E-15 T 23-10-2018 A3L04_06775 f5e512b8c17c84af3e9ee43a40071604 1005 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 628 998 2.3E-52 T 23-10-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 A3L04_06775 f5e512b8c17c84af3e9ee43a40071604 1005 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 265 519 3.1E-71 T 23-10-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 A3L04_06775 f5e512b8c17c84af3e9ee43a40071604 1005 SUPERFAMILY SSF74650 628 998 1.88E-65 T 23-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 A3L04_06775 f5e512b8c17c84af3e9ee43a40071604 1005 Pfam PF09261 Alpha mannosidase middle domain 526 603 6.2E-25 T 23-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 A3L04_06775 f5e512b8c17c84af3e9ee43a40071604 1005 SUPERFAMILY SSF88688 526 627 7.19E-24 T 23-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily A3L04_06775 f5e512b8c17c84af3e9ee43a40071604 1005 SUPERFAMILY SSF88713 258 524 5.34E-69 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L04_04750 a804db729a15332b6fdc984c5ae9e0b1 260 Gene3D G3DSA:3.60.20.10 5 247 1.7E-95 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L04_04750 a804db729a15332b6fdc984c5ae9e0b1 260 Hamap MF_00289_A Proteasome subunit alpha [prcA]. 5 234 48.947 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 A3L04_04750 a804db729a15332b6fdc984c5ae9e0b1 260 SUPERFAMILY SSF56235 7 241 1.85E-84 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L04_04750 a804db729a15332b6fdc984c5ae9e0b1 260 Pfam PF10584 Proteasome subunit A N-terminal signature 10 32 4.0E-12 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L04_04750 a804db729a15332b6fdc984c5ae9e0b1 260 SMART SM00948 10 32 3.4E-10 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L04_04750 a804db729a15332b6fdc984c5ae9e0b1 260 Pfam PF00227 Proteasome subunit 33 215 7.0E-67 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L04_04750 a804db729a15332b6fdc984c5ae9e0b1 260 TIGRFAM TIGR03633 arc_protsome_A: proteasome endopeptidase complex, archaeal, alpha subunit 8 235 2.7E-109 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 A3L04_04750 a804db729a15332b6fdc984c5ae9e0b1 260 ProSitePatterns PS00388 Proteasome alpha-type subunits signature. 10 32 - T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L04_04860 8d4b3966d222954fe9a9515f82c79c93 158 SUPERFAMILY SSF46785 4 57 8.24E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_04860 8d4b3966d222954fe9a9515f82c79c93 158 SUPERFAMILY SSF54909 65 145 6.84E-8 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L04_04860 8d4b3966d222954fe9a9515f82c79c93 158 Gene3D G3DSA:3.30.70.920 64 139 1.4E-8 T 23-10-2018 A3L04_04860 8d4b3966d222954fe9a9515f82c79c93 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 4.9E-10 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_04860 8d4b3966d222954fe9a9515f82c79c93 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 4.9E-10 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_04860 8d4b3966d222954fe9a9515f82c79c93 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 4.9E-10 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_04860 8d4b3966d222954fe9a9515f82c79c93 158 Pfam PF01037 Lrp/AsnC ligand binding domain 68 139 6.3E-6 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L04_04860 8d4b3966d222954fe9a9515f82c79c93 158 Gene3D G3DSA:1.10.10.10 3 50 4.1E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_04860 8d4b3966d222954fe9a9515f82c79c93 158 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 50 5.2E-12 T 23-10-2018 A3L04_04860 8d4b3966d222954fe9a9515f82c79c93 158 SMART SM00344 4 112 4.5E-10 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L04_02200 945502933f31ba576fc71df8dccbd9f6 185 Gene3D G3DSA:3.90.950.10 1 182 2.0E-65 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L04_02200 945502933f31ba576fc71df8dccbd9f6 185 Pfam PF02545 Maf-like protein 2 178 3.9E-57 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A3L04_02200 945502933f31ba576fc71df8dccbd9f6 185 SUPERFAMILY SSF52972 1 177 4.64E-56 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L04_02200 945502933f31ba576fc71df8dccbd9f6 185 Hamap MF_00528 Septum formation protein Maf [maf]. 1 183 30.592 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A3L04_02200 945502933f31ba576fc71df8dccbd9f6 185 PIRSF PIRSF006305 1 184 7.5E-57 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A3L04_02200 945502933f31ba576fc71df8dccbd9f6 185 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 177 4.0E-49 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A3L04_01655 df27b519ebb3b37a34ad08846813ae08 155 Pfam PF01037 Lrp/AsnC ligand binding domain 88 152 4.7E-8 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L04_01655 df27b519ebb3b37a34ad08846813ae08 155 Gene3D G3DSA:3.30.70.920 86 151 1.1E-9 T 23-10-2018 A3L04_01655 df27b519ebb3b37a34ad08846813ae08 155 Gene3D G3DSA:1.10.10.10 5 85 9.8E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_01655 df27b519ebb3b37a34ad08846813ae08 155 SUPERFAMILY SSF54909 86 153 2.68E-8 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L04_01655 df27b519ebb3b37a34ad08846813ae08 155 SUPERFAMILY SSF46785 6 85 6.73E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_01655 df27b519ebb3b37a34ad08846813ae08 155 SMART SM00419 22 73 4.9E-9 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L04_01655 df27b519ebb3b37a34ad08846813ae08 155 Pfam PF12802 MarR family 8 66 1.1E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A3L04_10430 a2fce307ccabf83e0ab25176ec132b5d 455 Gene3D G3DSA:3.40.1190.20 186 455 1.3E-96 T 23-10-2018 IPR029056 Ribokinase-like A3L04_10430 a2fce307ccabf83e0ab25176ec132b5d 455 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 24 448 1.2E-97 T 23-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 A3L04_10430 a2fce307ccabf83e0ab25176ec132b5d 455 Gene3D G3DSA:3.40.1190.20 109 185 3.0E-22 T 23-10-2018 IPR029056 Ribokinase-like A3L04_10430 a2fce307ccabf83e0ab25176ec132b5d 455 Gene3D G3DSA:3.40.1190.20 1 35 1.7E-10 T 23-10-2018 IPR029056 Ribokinase-like A3L04_10430 a2fce307ccabf83e0ab25176ec132b5d 455 SUPERFAMILY SSF53613 3 453 8.0E-159 T 23-10-2018 IPR029056 Ribokinase-like A3L04_10430 a2fce307ccabf83e0ab25176ec132b5d 455 PIRSF PIRSF015883 8 455 2.9E-170 T 23-10-2018 IPR015990 ADP-specific phosphofructokinase/glucokinase, archaeal GO:0000287|GO:0006096|GO:0016773 A3L04_10430 a2fce307ccabf83e0ab25176ec132b5d 455 Gene3D G3DSA:3.30.1110.20 36 108 6.2E-27 T 23-10-2018 A3L04_10430 a2fce307ccabf83e0ab25176ec132b5d 455 Hamap MF_00809 ADP-dependent glucokinase [glkA]. 2 454 63.13 T 23-10-2018 IPR031299 ADP-dependent glucokinase, archaeal KEGG: 00010+2.7.1.147|MetaCyc: PWY-6855 A3L04_03910 0e49fddf54bb423e805898feff35656f 344 Gene3D G3DSA:3.40.640.10 47 247 5.2E-77 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L04_03910 0e49fddf54bb423e805898feff35656f 344 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 197 210 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A3L04_03910 0e49fddf54bb423e805898feff35656f 344 Gene3D G3DSA:3.90.1150.10 17 333 5.2E-77 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L04_03910 0e49fddf54bb423e805898feff35656f 344 SUPERFAMILY SSF53383 13 337 5.28E-73 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L04_03910 0e49fddf54bb423e805898feff35656f 344 Pfam PF00155 Aminotransferase class I and II 18 332 1.8E-40 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L04_06900 d1fdd72e2f7c20a54b370d539640df9c 133 SUPERFAMILY SSF53146 3 116 5.62E-15 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L04_06900 d1fdd72e2f7c20a54b370d539640df9c 133 Gene3D G3DSA:3.30.420.130 2 126 6.5E-16 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L04_06900 d1fdd72e2f7c20a54b370d539640df9c 133 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 113 3.5E-15 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A3L04_03360 44e12df1a9264f9be23a088b6d091488 133 Pfam PF04472 Cell division protein SepF 55 130 2.6E-8 T 23-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 A3L04_03360 44e12df1a9264f9be23a088b6d091488 133 Gene3D G3DSA:3.30.110.150 48 133 7.8E-25 T 23-10-2018 IPR038594 SepF-like superfamily A3L04_03360 44e12df1a9264f9be23a088b6d091488 133 PIRSF PIRSF019313 1 133 7.0E-40 T 23-10-2018 IPR012426 Uncharacterised protein family SepF-related, archaea A3L04_09165 99d11cb30d007dbfa0defbf1ffa39e6d 385 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 17 369 1.2E-114 T 23-10-2018 IPR017439 Amidohydrolase GO:0016787 A3L04_09165 99d11cb30d007dbfa0defbf1ffa39e6d 385 SUPERFAMILY SSF53187 4 384 1.8E-88 T 23-10-2018 A3L04_09165 99d11cb30d007dbfa0defbf1ffa39e6d 385 Gene3D G3DSA:3.40.630.10 17 368 1.6E-137 T 23-10-2018 A3L04_09165 99d11cb30d007dbfa0defbf1ffa39e6d 385 Gene3D G3DSA:3.30.70.360 179 294 1.6E-137 T 23-10-2018 A3L04_09165 99d11cb30d007dbfa0defbf1ffa39e6d 385 SUPERFAMILY SSF55031 182 287 2.36E-29 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A3L04_09165 99d11cb30d007dbfa0defbf1ffa39e6d 385 Pfam PF01546 Peptidase family M20/M25/M40 73 378 7.0E-36 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A3L04_09165 99d11cb30d007dbfa0defbf1ffa39e6d 385 PIRSF PIRSF005962 1 385 2.4E-129 T 23-10-2018 IPR017439 Amidohydrolase GO:0016787 A3L04_09165 99d11cb30d007dbfa0defbf1ffa39e6d 385 Pfam PF07687 Peptidase dimerisation domain 183 278 4.8E-12 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A3L04_03210 98ab0952df30a4d1bb1cb95a2ea8c837 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 253 1.2E-29 T 23-10-2018 A3L04_03210 98ab0952df30a4d1bb1cb95a2ea8c837 259 Gene3D G3DSA:3.40.50.720 1 258 1.0E-45 T 23-10-2018 A3L04_03210 98ab0952df30a4d1bb1cb95a2ea8c837 259 SUPERFAMILY SSF51735 3 254 1.11E-48 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_03210 98ab0952df30a4d1bb1cb95a2ea8c837 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.3E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_03210 98ab0952df30a4d1bb1cb95a2ea8c837 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.3E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_03210 98ab0952df30a4d1bb1cb95a2ea8c837 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.3E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_03210 98ab0952df30a4d1bb1cb95a2ea8c837 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.3E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_03210 98ab0952df30a4d1bb1cb95a2ea8c837 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 2.3E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_03210 98ab0952df30a4d1bb1cb95a2ea8c837 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 2.3E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_04910 808e9f0d0e7f9ce5d8a95c58ed51a3ff 142 Pfam PF01951 Archease protein family (MTH1598/TM1083) 4 142 6.1E-48 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 A3L04_04910 808e9f0d0e7f9ce5d8a95c58ed51a3ff 142 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 8 128 4.0E-45 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 A3L04_04910 808e9f0d0e7f9ce5d8a95c58ed51a3ff 142 SUPERFAMILY SSF69819 2 142 2.62E-50 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 A3L04_04910 808e9f0d0e7f9ce5d8a95c58ed51a3ff 142 Hamap MF_01222 Protein archease. 2 142 44.14 T 23-10-2018 IPR022952 Archease, archaea A3L04_04910 808e9f0d0e7f9ce5d8a95c58ed51a3ff 142 Gene3D G3DSA:3.55.10.10 1 142 3.1E-58 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 A3L04_01715 abee9083a7cf211ac172a285fd0bd449 70 SUPERFAMILY SSF50346 1 66 2.16E-12 T 23-10-2018 IPR011033 PRC-barrel-like superfamily A3L04_01715 abee9083a7cf211ac172a285fd0bd449 70 Gene3D G3DSA:2.30.30.240 2 69 3.0E-6 T 23-10-2018 A3L04_01715 abee9083a7cf211ac172a285fd0bd449 70 Pfam PF05239 PRC-barrel domain 3 68 3.2E-13 T 23-10-2018 IPR027275 PRC-barrel domain A3L04_08600 89d6233d9f4c99e9175e081ec5b2c7e0 410 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 397 406 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 A3L04_08600 89d6233d9f4c99e9175e081ec5b2c7e0 410 Pfam PF00374 Nickel-dependent hydrogenase 38 114 1.2E-14 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L04_08600 89d6233d9f4c99e9175e081ec5b2c7e0 410 Pfam PF00374 Nickel-dependent hydrogenase 222 406 4.7E-17 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L04_08600 89d6233d9f4c99e9175e081ec5b2c7e0 410 Gene3D G3DSA:1.10.645.10 1 406 4.5E-102 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_08600 89d6233d9f4c99e9175e081ec5b2c7e0 410 SUPERFAMILY SSF56762 1 406 4.97E-95 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_01095 c5e506b5a24f660a94820aaea81fce0e 136 Gene3D G3DSA:3.10.580.10 1 136 5.1E-51 T 23-10-2018 A3L04_01095 c5e506b5a24f660a94820aaea81fce0e 136 Pfam PF00571 CBS domain 10 61 2.0E-12 T 23-10-2018 IPR000644 CBS domain A3L04_01095 c5e506b5a24f660a94820aaea81fce0e 136 Pfam PF00571 CBS domain 72 124 1.9E-16 T 23-10-2018 IPR000644 CBS domain A3L04_01095 c5e506b5a24f660a94820aaea81fce0e 136 SMART SM00116 79 126 7.5E-11 T 23-10-2018 IPR000644 CBS domain A3L04_01095 c5e506b5a24f660a94820aaea81fce0e 136 SMART SM00116 14 62 1.9E-10 T 23-10-2018 IPR000644 CBS domain A3L04_01095 c5e506b5a24f660a94820aaea81fce0e 136 SUPERFAMILY SSF54631 7 128 1.77E-35 T 23-10-2018 A3L04_00950 177820fa5180b8fbbd1401cf0b2d852f 349 Gene3D G3DSA:3.40.190.10 125 293 5.5E-134 T 23-10-2018 A3L04_00950 177820fa5180b8fbbd1401cf0b2d852f 349 TIGRFAM TIGR03730 tungstate_WtpA: tungstate ABC transporter binding protein WtpA 38 311 1.1E-125 T 23-10-2018 IPR022498 Tungstate ABC transporter, substrate-binding protein WtpA GO:1901359 A3L04_00950 177820fa5180b8fbbd1401cf0b2d852f 349 Gene3D G3DSA:3.40.190.10 39 342 5.5E-134 T 23-10-2018 A3L04_00950 177820fa5180b8fbbd1401cf0b2d852f 349 Pfam PF13531 Bacterial extracellular solute-binding protein 41 323 1.4E-34 T 23-10-2018 A3L04_00950 177820fa5180b8fbbd1401cf0b2d852f 349 SUPERFAMILY SSF53850 38 341 3.46E-51 T 23-10-2018 A3L04_00185 77a9dbb5fe10936114e60ccefb8508d7 358 Gene3D G3DSA:2.40.50.140 63 170 7.7E-22 T 23-10-2018 A3L04_00185 77a9dbb5fe10936114e60ccefb8508d7 358 Pfam PF01336 OB-fold nucleic acid binding domain 78 157 7.1E-11 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L04_00185 77a9dbb5fe10936114e60ccefb8508d7 358 Pfam PF08646 Replication factor-A C terminal domain 199 291 7.3E-11 T 23-10-2018 IPR013955 Replication factor A, C-terminal A3L04_00185 77a9dbb5fe10936114e60ccefb8508d7 358 SUPERFAMILY SSF50249 58 181 7.28E-23 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_00185 77a9dbb5fe10936114e60ccefb8508d7 358 SUPERFAMILY SSF50249 185 355 1.03E-22 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_00185 77a9dbb5fe10936114e60ccefb8508d7 358 Gene3D G3DSA:2.40.50.140 176 355 1.5E-14 T 23-10-2018 A3L04_05975 926438a1f7ce4bbe67372eb76364b74e 183 Gene3D G3DSA:3.30.2170.10 1 136 2.1E-36 T 23-10-2018 A3L04_05975 926438a1f7ce4bbe67372eb76364b74e 183 Gene3D G3DSA:3.30.2170.10 137 183 4.1E-7 T 23-10-2018 A3L04_05975 926438a1f7ce4bbe67372eb76364b74e 183 Pfam PF04493 Endonuclease V 11 129 1.5E-31 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 A3L04_05975 926438a1f7ce4bbe67372eb76364b74e 183 Pfam PF04493 Endonuclease V 136 176 3.3E-6 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 A3L04_01030 f2483f999b46749d65fc28507ef9cca9 233 Gene3D G3DSA:1.10.3740.10 101 172 2.6E-5 T 23-10-2018 IPR027419 CRISPR-associated protein Csx1, C-terminal A3L04_01030 f2483f999b46749d65fc28507ef9cca9 233 Gene3D G3DSA:3.40.50.10640 1 100 7.1E-16 T 23-10-2018 A3L04_01030 f2483f999b46749d65fc28507ef9cca9 233 SUPERFAMILY SSF160980 2 210 4.45E-22 T 23-10-2018 A3L04_06890 a4da6cbd63d67cf422ff251bbe12832b 64 Pfam PF00096 Zinc finger, C2H2 type 19 41 1.7E-5 T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 A3L04_06890 a4da6cbd63d67cf422ff251bbe12832b 64 SMART SM00355 18 41 0.0088 T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 A3L04_06890 a4da6cbd63d67cf422ff251bbe12832b 64 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 20 41 - T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 A3L04_02010 373997b8d9c07127a53781ce9465caf0 198 Pfam PF01991 ATP synthase (E/31 kDa) subunit 10 197 3.5E-37 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L04_02010 373997b8d9c07127a53781ce9465caf0 198 Gene3D G3DSA:1.20.5.620 18 98 2.1E-27 T 23-10-2018 A3L04_02010 373997b8d9c07127a53781ce9465caf0 198 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 2 198 15.516 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L04_02010 373997b8d9c07127a53781ce9465caf0 198 Gene3D G3DSA:3.30.2320.30 100 198 1.2E-19 T 23-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L04_02010 373997b8d9c07127a53781ce9465caf0 198 SUPERFAMILY SSF160527 81 198 2.35E-29 T 23-10-2018 A3L04_02145 a95c4e8f7a33411bc440e93b9c3f876c 414 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 6 14 - T 23-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A3L04_02145 a95c4e8f7a33411bc440e93b9c3f876c 414 Pfam PF00764 Arginosuccinate synthase 4 384 6.3E-172 T 23-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A3L04_02145 a95c4e8f7a33411bc440e93b9c3f876c 414 Hamap MF_00005 Argininosuccinate synthase [argG]. 1 391 53.231 T 23-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A3L04_02145 a95c4e8f7a33411bc440e93b9c3f876c 414 Gene3D G3DSA:3.40.50.620 4 166 1.2E-156 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_02145 a95c4e8f7a33411bc440e93b9c3f876c 414 TIGRFAM TIGR00032 argG: argininosuccinate synthase 2 385 9.5E-165 T 23-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A3L04_02145 a95c4e8f7a33411bc440e93b9c3f876c 414 SUPERFAMILY SSF52402 1 199 1.49E-49 T 23-10-2018 A3L04_02145 a95c4e8f7a33411bc440e93b9c3f876c 414 SUPERFAMILY SSF69864 165 390 1.96E-94 T 23-10-2018 A3L04_02145 a95c4e8f7a33411bc440e93b9c3f876c 414 Gene3D G3DSA:3.90.1260.10 61 347 1.2E-156 T 23-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A3L04_02145 a95c4e8f7a33411bc440e93b9c3f876c 414 Gene3D G3DSA:1.20.5.470 357 388 7.7E-7 T 23-10-2018 A3L04_02145 a95c4e8f7a33411bc440e93b9c3f876c 414 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 114 125 - T 23-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 Gene3D G3DSA:1.10.8.60 606 669 4.9E-28 T 23-10-2018 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 SMART SM00305 478 526 2.8E-8 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 SMART SM00382 45 612 9.1E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 Gene3D G3DSA:3.10.28.10 231 403 9.4E-27 T 23-10-2018 IPR027434 Homing endonuclease A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 497 521 3.0E-4 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 86 176 8.5E-10 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 15 70 2.3E-8 T 23-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 SUPERFAMILY SSF51294 85 521 1.96E-26 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 SUPERFAMILY SSF55608 228 314 5.95E-5 T 23-10-2018 IPR027434 Homing endonuclease A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 SUPERFAMILY SSF48019 671 760 4.08E-23 T 23-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 SUPERFAMILY SSF55608 328 396 6.8E-13 T 23-10-2018 IPR027434 Homing endonuclease A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 Gene3D G3DSA:1.20.272.10 670 763 1.5E-37 T 23-10-2018 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 PRINTS PR00379 Intein signature 372 387 2.1E-16 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 PRINTS PR00379 Intein signature 235 247 2.1E-16 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 PRINTS PR00379 Intein signature 163 176 2.1E-16 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 PRINTS PR00379 Intein signature 495 512 2.1E-16 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 PRINTS PR00379 Intein signature 345 357 2.1E-16 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 PRINTS PR00379 Intein signature 515 524 2.1E-16 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 Pfam PF13177 DNA polymerase III, delta subunit 523 605 7.3E-11 T 23-10-2018 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 Pfam PF08542 Replication factor C C-terminal domain 671 756 2.1E-21 T 23-10-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 Pfam PF14890 Intein splicing domain 108 520 3.7E-22 T 23-10-2018 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 Pfam PF14528 LAGLIDADG-like domain 345 394 8.9E-5 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 Pfam PF14528 LAGLIDADG-like domain 238 316 2.0E-5 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 SMART SM00306 83 200 2.3E-17 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 Gene3D G3DSA:3.40.50.300 474 605 1.2E-25 T 23-10-2018 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 Gene3D G3DSA:3.40.50.300 1 188 7.8E-31 T 23-10-2018 A3L04_01560 bb51054f5a5a2d7f21bf6d2ac21b9ce0 763 SUPERFAMILY SSF52540 13 655 6.53E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_02785 bf04ce3291adc31764b0a237ac54c099 294 Pfam PF03787 RAMP superfamily 11 290 3.3E-29 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein A3L04_02785 bf04ce3291adc31764b0a237ac54c099 294 TIGRFAM TIGR02580 cas_RAMP_Cmr4: CRISPR type III-B/RAMP module RAMP protein Cmr4 7 290 4.5E-83 T 23-10-2018 IPR013410 CRISPR-associated RAMP Cmr4 A3L04_10345 a07ed7d3ac76a7e2a4ba258580eafe4f 252 Hamap MF_00226_A Putative competence-damage inducible protein [cinA]. 1 249 39.018 T 23-10-2018 IPR023055 Putative competence-damage inducible protein, Archaea A3L04_10345 a07ed7d3ac76a7e2a4ba258580eafe4f 252 Pfam PF00994 Probable molybdopterin binding domain 4 176 9.9E-33 T 23-10-2018 IPR001453 MoaB/Mog domain A3L04_10345 a07ed7d3ac76a7e2a4ba258580eafe4f 252 SMART SM00852 4 179 4.7E-41 T 23-10-2018 IPR001453 MoaB/Mog domain A3L04_10345 a07ed7d3ac76a7e2a4ba258580eafe4f 252 Gene3D G3DSA:3.40.980.10 2 178 7.8E-54 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L04_10345 a07ed7d3ac76a7e2a4ba258580eafe4f 252 SUPERFAMILY SSF53218 1 203 6.28E-40 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L04_03580 e6abc5b0e1e4d0444d8e56631bbdb4e3 259 Pfam PF05763 Protein of unknown function (DUF835) 136 256 5.3E-34 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L04_01815 f17f6e30468818fea7f035399ab00a9f 304 SMART SM00966 8 54 3.3E-11 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L04_01815 f17f6e30468818fea7f035399ab00a9f 304 SUPERFAMILY SSF109755 125 301 7.06E-20 T 23-10-2018 A3L04_01815 f17f6e30468818fea7f035399ab00a9f 304 Gene3D G3DSA:1.20.58.220 135 236 7.2E-14 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L04_01815 f17f6e30468818fea7f035399ab00a9f 304 Pfam PF01895 PhoU domain 139 230 4.2E-16 T 23-10-2018 IPR026022 PhoU domain A3L04_01815 f17f6e30468818fea7f035399ab00a9f 304 SUPERFAMILY SSF89447 12 60 1.92E-5 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L04_01815 f17f6e30468818fea7f035399ab00a9f 304 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 2.0E-10 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L04_01430 262b0ad97e31dcce7e63e4363d15b3f0 249 Hamap MF_00722 Endonuclease NucS [nucS]. 28 238 38.466 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 A3L04_01430 262b0ad97e31dcce7e63e4363d15b3f0 249 Gene3D G3DSA:3.40.1350.10 121 233 3.8E-44 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A3L04_01430 262b0ad97e31dcce7e63e4363d15b3f0 249 Pfam PF01939 Endonuclease NucS 28 247 6.9E-84 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 A3L04_01430 262b0ad97e31dcce7e63e4363d15b3f0 249 Gene3D G3DSA:2.70.180.20 1 120 4.6E-47 T 23-10-2018 A3L04_02885 d33bf64d685847accdbdab249f470448 341 Pfam PF04283 Chemotaxis signal transduction system protein F from archaea 4 228 2.6E-17 T 23-10-2018 IPR007381 Chemotaxis signal transduction system protein F A3L04_02885 d33bf64d685847accdbdab249f470448 341 Gene3D G3DSA:1.10.10.10 246 338 2.8E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_02885 d33bf64d685847accdbdab249f470448 341 SUPERFAMILY SSF46785 237 335 6.68E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_07430 0b29a81dd5964444e84132adb2070622 75 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 4 43 1.6E-17 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L04_07430 0b29a81dd5964444e84132adb2070622 75 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 48 4.6E-15 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L04_07430 0b29a81dd5964444e84132adb2070622 75 SMART SM00966 4 49 5.1E-15 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L04_07430 0b29a81dd5964444e84132adb2070622 75 SUPERFAMILY SSF89447 2 61 4.36E-14 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L04_07430 0b29a81dd5964444e84132adb2070622 75 Gene3D G3DSA:2.10.260.10 2 42 4.6E-17 T 23-10-2018 A3L04_09460 52c4701e24cc0f77443fb80eb33fe69f 349 Pfam PF01861 Protein of unknown function DUF43 105 348 5.9E-125 T 23-10-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal A3L04_09460 52c4701e24cc0f77443fb80eb33fe69f 349 SUPERFAMILY SSF53335 164 275 2.62E-7 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_09460 52c4701e24cc0f77443fb80eb33fe69f 349 PIRSF PIRSF005895 1 349 7.4E-165 T 23-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 A3L04_09460 52c4701e24cc0f77443fb80eb33fe69f 349 Hamap MF_01947 N(4)-bis(aminopropyl)spermidine synthase [bpsA]. 15 349 50.303 T 23-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 A3L04_09460 52c4701e24cc0f77443fb80eb33fe69f 349 Gene3D G3DSA:3.40.50.150 100 325 1.8E-85 T 23-10-2018 A3L04_09460 52c4701e24cc0f77443fb80eb33fe69f 349 Gene3D G3DSA:1.10.10.10 1 82 1.9E-34 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_03405 98caf6d4fb49f488ba0a14aaf4928bfc 210 SUPERFAMILY SSF54814 7 93 1.1E-24 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L04_03405 98caf6d4fb49f488ba0a14aaf4928bfc 210 Hamap MF_01309_A 30S ribosomal protein S3 [rpsC]. 2 197 42.508 T 23-10-2018 IPR027488 Ribosomal protein S3, archaeal GO:0003735|GO:0006412|GO:0015935 A3L04_03405 98caf6d4fb49f488ba0a14aaf4928bfc 210 Gene3D G3DSA:3.30.1140.32 87 210 2.5E-42 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03405 98caf6d4fb49f488ba0a14aaf4928bfc 210 Pfam PF07650 KH domain 17 88 1.2E-14 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03405 98caf6d4fb49f488ba0a14aaf4928bfc 210 SMART SM00322 38 104 3.0E-8 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L04_03405 98caf6d4fb49f488ba0a14aaf4928bfc 210 Gene3D G3DSA:3.30.300.20 1 86 3.6E-29 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L04_03405 98caf6d4fb49f488ba0a14aaf4928bfc 210 TIGRFAM TIGR01008 uS3_euk_arch: ribosomal protein uS3 3 197 1.1E-94 T 23-10-2018 IPR005703 Ribosomal protein S3, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03405 98caf6d4fb49f488ba0a14aaf4928bfc 210 Pfam PF00189 Ribosomal protein S3, C-terminal domain 99 182 1.6E-23 T 23-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03405 98caf6d4fb49f488ba0a14aaf4928bfc 210 SUPERFAMILY SSF54821 86 186 7.32E-26 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_08195 4de4d18db9d30ce9e95c43547a6bc8d7 265 PIRSF PIRSF000388 1 265 1.4E-104 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A3L04_08195 4de4d18db9d30ce9e95c43547a6bc8d7 265 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 262 41.015 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A3L04_08195 4de4d18db9d30ce9e95c43547a6bc8d7 265 SUPERFAMILY SSF51621 4 262 2.51E-102 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A3L04_08195 4de4d18db9d30ce9e95c43547a6bc8d7 265 Gene3D G3DSA:3.20.20.60 2 265 5.5E-110 T 23-10-2018 A3L04_08195 4de4d18db9d30ce9e95c43547a6bc8d7 265 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 257 2.4E-107 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A3L04_08195 4de4d18db9d30ce9e95c43547a6bc8d7 265 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 10 261 5.8E-92 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A3L04_03535 56d2f5e37adf579bea01ba64687b8993 205 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 1 197 4.2E-37 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 A3L04_03535 56d2f5e37adf579bea01ba64687b8993 205 Gene3D G3DSA:3.90.320.10 2 200 4.1E-21 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal A3L04_05900 d8df7efa7a9a9b6b3728cfa97f400658 388 Gene3D G3DSA:3.40.47.10 4 387 2.1E-126 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L04_05900 d8df7efa7a9a9b6b3728cfa97f400658 388 SUPERFAMILY SSF53901 4 229 6.85E-47 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L04_05900 d8df7efa7a9a9b6b3728cfa97f400658 388 Pfam PF02803 Thiolase, C-terminal domain 250 355 8.7E-11 T 23-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 A3L04_05900 d8df7efa7a9a9b6b3728cfa97f400658 388 SUPERFAMILY SSF53901 233 386 3.85E-30 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L04_05900 d8df7efa7a9a9b6b3728cfa97f400658 388 PIRSF PIRSF000429 1 386 3.1E-67 T 23-10-2018 IPR002155 Thiolase GO:0016747 A3L04_05900 d8df7efa7a9a9b6b3728cfa97f400658 388 Pfam PF00108 Thiolase, N-terminal domain 5 220 8.3E-28 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 A3L04_04100 882e7c681f608d3e0fcb5ad25d610507 78 Gene3D G3DSA:3.30.160.250 4 77 1.1E-8 T 23-10-2018 A3L04_04100 882e7c681f608d3e0fcb5ad25d610507 78 SUPERFAMILY SSF143100 8 60 5.23E-11 T 23-10-2018 IPR035069 TTHA1013/TTHA0281-like A3L04_05660 91b2c62400b7a5b647cc88e7026c6aef 368 Gene3D G3DSA:3.40.50.1980 169 364 6.4E-83 T 23-10-2018 A3L04_05660 91b2c62400b7a5b647cc88e7026c6aef 368 SUPERFAMILY SSF53807 32 339 1.77E-60 T 23-10-2018 A3L04_05660 91b2c62400b7a5b647cc88e7026c6aef 368 Pfam PF01497 Periplasmic binding protein 48 289 1.1E-27 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain A3L04_05660 91b2c62400b7a5b647cc88e7026c6aef 368 Gene3D G3DSA:3.40.50.1980 22 168 8.5E-62 T 23-10-2018 A3L04_08630 052b77b5f178c79046a253b93aee5454 533 Pfam PF13353 4Fe-4S single cluster domain 131 237 8.4E-9 T 23-10-2018 A3L04_08630 052b77b5f178c79046a253b93aee5454 533 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 384 470 1.7E-13 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A3L04_08630 052b77b5f178c79046a253b93aee5454 533 Gene3D G3DSA:3.20.20.70 130 438 1.6E-54 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_08630 052b77b5f178c79046a253b93aee5454 533 SMART SM00729 129 329 1.5E-14 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L04_08630 052b77b5f178c79046a253b93aee5454 533 Pfam PF13186 Iron-sulfur cluster-binding domain 384 444 9.1E-10 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A3L04_08630 052b77b5f178c79046a253b93aee5454 533 SUPERFAMILY SSF102114 128 451 2.62E-73 T 23-10-2018 A3L04_08630 052b77b5f178c79046a253b93aee5454 533 Pfam PF04055 Radical SAM superfamily 134 290 1.3E-24 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_02455 1058098f9c2ae17c799abca20a30bdae 912 Pfam PF01411 tRNA synthetases class II (A) 61 602 4.3E-165 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A3L04_02455 1058098f9c2ae17c799abca20a30bdae 912 SMART SM00863 701 744 2.6E-17 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L04_02455 1058098f9c2ae17c799abca20a30bdae 912 Pfam PF02272 DHHA1 domain 781 911 7.7E-21 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L04_02455 1058098f9c2ae17c799abca20a30bdae 912 Gene3D G3DSA:3.10.310.40 812 911 5.7E-20 T 23-10-2018 A3L04_02455 1058098f9c2ae17c799abca20a30bdae 912 PRINTS PR00980 Alanyl-tRNA synthetase signature 336 352 4.6E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L04_02455 1058098f9c2ae17c799abca20a30bdae 912 PRINTS PR00980 Alanyl-tRNA synthetase signature 360 373 4.6E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L04_02455 1058098f9c2ae17c799abca20a30bdae 912 PRINTS PR00980 Alanyl-tRNA synthetase signature 127 138 4.6E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L04_02455 1058098f9c2ae17c799abca20a30bdae 912 PRINTS PR00980 Alanyl-tRNA synthetase signature 245 258 4.6E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L04_02455 1058098f9c2ae17c799abca20a30bdae 912 PRINTS PR00980 Alanyl-tRNA synthetase signature 206 217 4.6E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L04_02455 1058098f9c2ae17c799abca20a30bdae 912 SUPERFAMILY SSF55186 602 751 9.68E-49 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A3L04_02455 1058098f9c2ae17c799abca20a30bdae 912 Hamap MF_00036_A Alanine--tRNA ligase [alaS]. 4 908 24.181 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A3L04_02455 1058098f9c2ae17c799abca20a30bdae 912 TIGRFAM TIGR03683 A-tRNA_syn_arch: alanine--tRNA ligase 5 909 0.0 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A3L04_02455 1058098f9c2ae17c799abca20a30bdae 912 SUPERFAMILY SSF101353 306 505 2.88E-50 T 23-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A3L04_02455 1058098f9c2ae17c799abca20a30bdae 912 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 701 743 9.5E-15 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L04_02455 1058098f9c2ae17c799abca20a30bdae 912 Gene3D G3DSA:3.30.54.20 674 725 2.5E-30 T 23-10-2018 A3L04_02455 1058098f9c2ae17c799abca20a30bdae 912 Gene3D G3DSA:3.30.980.10 604 673 6.8E-22 T 23-10-2018 A3L04_02455 1058098f9c2ae17c799abca20a30bdae 912 Gene3D G3DSA:2.40.30.130 501 598 6.4E-38 T 23-10-2018 A3L04_02455 1058098f9c2ae17c799abca20a30bdae 912 Gene3D G3DSA:3.30.930.10 1 260 4.2E-116 T 23-10-2018 A3L04_02455 1058098f9c2ae17c799abca20a30bdae 912 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 61 893 1.6E-239 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L04_02455 1058098f9c2ae17c799abca20a30bdae 912 SUPERFAMILY SSF50447 511 596 2.15E-19 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L04_02455 1058098f9c2ae17c799abca20a30bdae 912 SUPERFAMILY SSF55681 57 264 8.57E-59 T 23-10-2018 A3L04_02185 62cf2c68e7ab961065910cbd40d32682 270 SUPERFAMILY SSF56281 3 254 7.45E-39 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_02185 62cf2c68e7ab961065910cbd40d32682 270 Gene3D G3DSA:3.60.15.10 1 252 1.9E-30 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_02185 62cf2c68e7ab961065910cbd40d32682 270 Pfam PF12706 Beta-lactamase superfamily domain 33 219 1.5E-24 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_00030 c49675a86787c34a2a0d540f6e564e54 158 SUPERFAMILY SSF88723 7 149 4.71E-19 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_00030 c49675a86787c34a2a0d540f6e564e54 158 Gene3D G3DSA:3.40.50.1010 2 151 1.1E-32 T 23-10-2018 A3L04_00715 c05554585f34a3b1ef76a70f67d9ee33 227 Gene3D G3DSA:3.40.50.150 52 227 2.4E-73 T 23-10-2018 A3L04_00715 c05554585f34a3b1ef76a70f67d9ee33 227 Pfam PF01269 Fibrillarin 5 225 1.1E-101 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L04_00715 c05554585f34a3b1ef76a70f67d9ee33 227 ProSitePatterns PS00566 Fibrillarin signature. 99 113 - T 23-10-2018 IPR020813 Fibrillarin, conserved site GO:0003723|GO:0006364|GO:0008168 A3L04_00715 c05554585f34a3b1ef76a70f67d9ee33 227 PIRSF PIRSF006540 1 227 3.7E-101 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L04_00715 c05554585f34a3b1ef76a70f67d9ee33 227 Gene3D G3DSA:3.30.200.20 1 51 2.4E-27 T 23-10-2018 A3L04_00715 c05554585f34a3b1ef76a70f67d9ee33 227 PRINTS PR00052 Fibrillarin signature 24 43 9.7E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L04_00715 c05554585f34a3b1ef76a70f67d9ee33 227 PRINTS PR00052 Fibrillarin signature 74 95 9.7E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L04_00715 c05554585f34a3b1ef76a70f67d9ee33 227 PRINTS PR00052 Fibrillarin signature 99 116 9.7E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L04_00715 c05554585f34a3b1ef76a70f67d9ee33 227 PRINTS PR00052 Fibrillarin signature 47 66 9.7E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L04_00715 c05554585f34a3b1ef76a70f67d9ee33 227 PRINTS PR00052 Fibrillarin signature 124 153 9.7E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L04_00715 c05554585f34a3b1ef76a70f67d9ee33 227 PRINTS PR00052 Fibrillarin signature 154 183 9.7E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L04_00715 c05554585f34a3b1ef76a70f67d9ee33 227 PRINTS PR00052 Fibrillarin signature 205 226 9.7E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L04_00715 c05554585f34a3b1ef76a70f67d9ee33 227 SUPERFAMILY SSF53335 3 226 3.14E-62 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_00715 c05554585f34a3b1ef76a70f67d9ee33 227 Hamap MF_00351 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase [flpA]. 17 227 44.572 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L04_00715 c05554585f34a3b1ef76a70f67d9ee33 227 SMART SM01206 4 227 9.7E-147 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L04_04370 8e5263063e254f117e3177ce0ba7bba1 142 Gene3D G3DSA:3.90.1180.10 1 142 1.8E-58 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 A3L04_04370 8e5263063e254f117e3177ce0ba7bba1 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 79 102 - T 23-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 A3L04_04370 8e5263063e254f117e3177ce0ba7bba1 142 SUPERFAMILY SSF52161 2 142 4.19E-44 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 A3L04_04370 8e5263063e254f117e3177ce0ba7bba1 142 TIGRFAM TIGR01077 L13_A_E: ribosomal protein uL13 3 142 1.5E-66 T 23-10-2018 IPR005755 Ribosomal protein L13, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 A3L04_04370 8e5263063e254f117e3177ce0ba7bba1 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 1 132 21.163 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A3L04_04370 8e5263063e254f117e3177ce0ba7bba1 142 Pfam PF00572 Ribosomal protein L13 3 105 1.6E-11 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A3L04_04370 8e5263063e254f117e3177ce0ba7bba1 142 PIRSF PIRSF002181 1 142 4.4E-43 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A3L04_10015 2bad59f1e18442992655105f83722cf2 202 TIGRFAM TIGR03334 IOR_beta: indolepyruvate ferredoxin oxidoreductase, beta subunit 4 194 8.7E-92 T 23-10-2018 IPR017719 Indolepyruvate ferredoxin oxidoreductase, beta subunit GO:0043805|GO:0055114 A3L04_10015 2bad59f1e18442992655105f83722cf2 202 SUPERFAMILY SSF53323 4 199 1.44E-44 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L04_10015 2bad59f1e18442992655105f83722cf2 202 Gene3D G3DSA:3.40.920.10 1 201 1.2E-48 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L04_10015 2bad59f1e18442992655105f83722cf2 202 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 193 3.4E-39 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L04_05260 90b41d09b7a2d71ca8470ae9d3349b34 283 SUPERFAMILY SSF52343 110 249 4.03E-11 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L04_05260 90b41d09b7a2d71ca8470ae9d3349b34 283 SUPERFAMILY SSF63380 3 91 3.14E-12 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L04_05260 90b41d09b7a2d71ca8470ae9d3349b34 283 Gene3D G3DSA:3.40.50.80 99 204 1.3E-12 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L04_05260 90b41d09b7a2d71ca8470ae9d3349b34 283 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 214 250 4.4E-13 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L04_05260 90b41d09b7a2d71ca8470ae9d3349b34 283 PIRSF PIRSF006816 1 256 1.7E-43 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L04_05260 90b41d09b7a2d71ca8470ae9d3349b34 283 Gene3D G3DSA:2.40.30.10 2 91 2.3E-11 T 23-10-2018 A3L04_00510 700c7ee5e51d72181329147700a53745 469 PIRSF PIRSF006677 1 469 2.2E-177 T 23-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A3L04_00510 700c7ee5e51d72181329147700a53745 469 TIGRFAM TIGR02751 PEPCase_arch: phosphoenolpyruvate carboxylase 2 441 7.4E-179 T 23-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A3L04_00510 700c7ee5e51d72181329147700a53745 469 Pfam PF14010 Phosphoenolpyruvate carboxylase 2 435 1.4E-164 T 23-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A3L04_00510 700c7ee5e51d72181329147700a53745 469 SUPERFAMILY SSF51621 93 418 4.08E-37 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A3L04_00510 700c7ee5e51d72181329147700a53745 469 Hamap MF_01904 Phosphoenolpyruvate carboxylase [ppcA]. 1 469 38.076 T 23-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A3L04_05185 297287d858e4842bcfdf375222bb3e9b 347 SUPERFAMILY SSF53697 4 343 8.35E-64 T 23-10-2018 A3L04_05185 297287d858e4842bcfdf375222bb3e9b 347 Gene3D G3DSA:3.40.50.10490 190 345 1.8E-27 T 23-10-2018 A3L04_05185 297287d858e4842bcfdf375222bb3e9b 347 Gene3D G3DSA:3.40.50.10490 1 189 9.5E-46 T 23-10-2018 A3L04_05185 297287d858e4842bcfdf375222bb3e9b 347 Pfam PF01380 SIS domain 33 154 4.0E-22 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A3L04_05185 297287d858e4842bcfdf375222bb3e9b 347 Pfam PF01380 SIS domain 202 327 6.9E-6 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A3L04_06820 cb30777a29e7ad29233dfafa6410c6ae 335 PRINTS PR01270 Histone deacetylase superfamily signature 124 147 2.1E-11 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A3L04_06820 cb30777a29e7ad29233dfafa6410c6ae 335 PRINTS PR01270 Histone deacetylase superfamily signature 241 251 2.1E-11 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A3L04_06820 cb30777a29e7ad29233dfafa6410c6ae 335 PRINTS PR01270 Histone deacetylase superfamily signature 157 172 2.1E-11 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A3L04_06820 cb30777a29e7ad29233dfafa6410c6ae 335 Pfam PF00850 Histone deacetylase domain 20 290 2.5E-68 T 23-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A3L04_06820 cb30777a29e7ad29233dfafa6410c6ae 335 Gene3D G3DSA:3.40.800.20 3 329 6.3E-83 T 23-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A3L04_06820 cb30777a29e7ad29233dfafa6410c6ae 335 SUPERFAMILY SSF52768 5 328 2.25E-88 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily A3L04_06965 0abf967ab41a7b0a345e3256350e7932 138 Pfam PF01287 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 70 134 5.7E-13 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 A3L04_06965 0abf967ab41a7b0a345e3256350e7932 138 PIRSF PIRSF003025 1 138 6.8E-47 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 A3L04_06965 0abf967ab41a7b0a345e3256350e7932 138 TIGRFAM TIGR00037 eIF_5A: translation elongation factor IF5A 4 134 1.1E-49 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 A3L04_06965 0abf967ab41a7b0a345e3256350e7932 138 SUPERFAMILY SSF50104 5 78 3.46E-21 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L04_06965 0abf967ab41a7b0a345e3256350e7932 138 SMART SM01376 70 134 1.1E-20 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 A3L04_06965 0abf967ab41a7b0a345e3256350e7932 138 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 9 40 1.8E-4 T 23-10-2018 IPR013185 Translation elongation factor, KOW-like A3L04_06965 0abf967ab41a7b0a345e3256350e7932 138 Hamap MF_00085 Translation initiation factor 5A [eif5a]. 3 133 35.648 T 23-10-2018 IPR022847 Translation elongation factor IF5A, archaeal A3L04_06965 0abf967ab41a7b0a345e3256350e7932 138 Gene3D G3DSA:2.40.50.140 71 135 5.9E-30 T 23-10-2018 A3L04_06965 0abf967ab41a7b0a345e3256350e7932 138 Gene3D G3DSA:2.30.30.30 1 70 1.8E-28 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L04_06965 0abf967ab41a7b0a345e3256350e7932 138 SUPERFAMILY SSF50249 71 133 6.43E-15 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_06965 0abf967ab41a7b0a345e3256350e7932 138 ProSitePatterns PS00302 Eukaryotic initiation factor 5A hypusine signature. 35 42 - T 23-10-2018 IPR019769 Translation elongation factor, IF5A, hypusine site GO:0003723|GO:0003746|GO:0043022|GO:0045901|GO:0045905 A3L04_04580 6089097508b2ccce5aca01053c75d01c 141 SMART SM00344 2 108 1.0E-51 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L04_04580 6089097508b2ccce5aca01053c75d01c 141 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 49 2.9E-15 T 23-10-2018 A3L04_04580 6089097508b2ccce5aca01053c75d01c 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 5.9E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_04580 6089097508b2ccce5aca01053c75d01c 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 5.9E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_04580 6089097508b2ccce5aca01053c75d01c 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 5.9E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_04580 6089097508b2ccce5aca01053c75d01c 141 SUPERFAMILY SSF46785 1 62 1.81E-19 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_04580 6089097508b2ccce5aca01053c75d01c 141 Gene3D G3DSA:3.30.70.920 65 141 3.2E-19 T 23-10-2018 A3L04_04580 6089097508b2ccce5aca01053c75d01c 141 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 23-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A3L04_04580 6089097508b2ccce5aca01053c75d01c 141 SUPERFAMILY SSF54909 62 141 5.63E-17 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L04_04580 6089097508b2ccce5aca01053c75d01c 141 Gene3D G3DSA:1.10.10.10 1 52 1.4E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_04580 6089097508b2ccce5aca01053c75d01c 141 Pfam PF01037 Lrp/AsnC ligand binding domain 70 139 3.9E-14 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L04_07535 5c034eef8e24b5eacf6dc639ddd4b59d 206 SUPERFAMILY SSF54862 21 118 2.09E-23 T 23-10-2018 A3L04_07535 5c034eef8e24b5eacf6dc639ddd4b59d 206 Pfam PF12838 4Fe-4S dicluster domain 59 113 1.3E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L04_07535 5c034eef8e24b5eacf6dc639ddd4b59d 206 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_07535 5c034eef8e24b5eacf6dc639ddd4b59d 206 Gene3D G3DSA:3.30.70.3270 38 177 3.9E-24 T 23-10-2018 A3L04_03415 19d66997ad5f98900d30322017f12131 98 Hamap MF_00604 Protein translation factor SUI1 homolog. 2 93 26.997 T 23-10-2018 IPR022851 Translation factor SUI1 homolog, archaea A3L04_03415 19d66997ad5f98900d30322017f12131 98 Gene3D G3DSA:3.30.780.10 20 98 4.4E-29 T 23-10-2018 A3L04_03415 19d66997ad5f98900d30322017f12131 98 SUPERFAMILY SSF55159 5 90 1.06E-23 T 23-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 A3L04_03415 19d66997ad5f98900d30322017f12131 98 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 4 96 4.9E-37 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 A3L04_03415 19d66997ad5f98900d30322017f12131 98 Pfam PF01253 Translation initiation factor SUI1 20 90 2.8E-20 T 23-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 A3L04_03415 19d66997ad5f98900d30322017f12131 98 PIRSF PIRSF037511 5 97 2.3E-26 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 A3L04_08410 d0bf38bb8245cd1f93f51b1313d7f148 292 Hamap MF_00384 Homoserine kinase [thrB]. 3 292 28.429 T 23-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A3L04_08410 d0bf38bb8245cd1f93f51b1313d7f148 292 Pfam PF00288 GHMP kinases N terminal domain 75 139 3.8E-14 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A3L04_08410 d0bf38bb8245cd1f93f51b1313d7f148 292 TIGRFAM TIGR00191 thrB: homoserine kinase 1 266 3.7E-59 T 23-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A3L04_08410 d0bf38bb8245cd1f93f51b1313d7f148 292 PIRSF PIRSF000676 1 292 2.9E-82 T 23-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A3L04_08410 d0bf38bb8245cd1f93f51b1313d7f148 292 Pfam PF08544 GHMP kinases C terminal 200 272 3.5E-12 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain A3L04_08410 d0bf38bb8245cd1f93f51b1313d7f148 292 SUPERFAMILY SSF55060 157 274 3.42E-30 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A3L04_08410 d0bf38bb8245cd1f93f51b1313d7f148 292 PRINTS PR00958 Homoserine kinase signature 126 139 8.1E-29 T 23-10-2018 A3L04_08410 d0bf38bb8245cd1f93f51b1313d7f148 292 PRINTS PR00958 Homoserine kinase signature 87 102 8.1E-29 T 23-10-2018 A3L04_08410 d0bf38bb8245cd1f93f51b1313d7f148 292 PRINTS PR00958 Homoserine kinase signature 8 23 8.1E-29 T 23-10-2018 A3L04_08410 d0bf38bb8245cd1f93f51b1313d7f148 292 PRINTS PR00958 Homoserine kinase signature 241 256 8.1E-29 T 23-10-2018 A3L04_08410 d0bf38bb8245cd1f93f51b1313d7f148 292 PRINTS PR00958 Homoserine kinase signature 162 179 8.1E-29 T 23-10-2018 A3L04_08410 d0bf38bb8245cd1f93f51b1313d7f148 292 Gene3D G3DSA:3.30.230.10 1 158 1.2E-41 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L04_08410 d0bf38bb8245cd1f93f51b1313d7f148 292 Gene3D G3DSA:3.30.70.890 159 284 2.1E-38 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A3L04_08410 d0bf38bb8245cd1f93f51b1313d7f148 292 SUPERFAMILY SSF54211 1 151 6.83E-30 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L04_00090 623705ecd14b5a87a8a01f992e713005 389 SUPERFAMILY SSF51690 111 385 3.09E-78 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A3L04_00090 623705ecd14b5a87a8a01f992e713005 389 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 51 112 1.4E-4 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A3L04_00090 623705ecd14b5a87a8a01f992e713005 389 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 114 302 8.4E-28 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 A3L04_00090 623705ecd14b5a87a8a01f992e713005 389 Gene3D G3DSA:3.90.1170.20 1 105 9.8E-47 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 A3L04_00090 623705ecd14b5a87a8a01f992e713005 389 SUPERFAMILY SSF54675 2 114 2.49E-32 T 23-10-2018 A3L04_00090 623705ecd14b5a87a8a01f992e713005 389 Gene3D G3DSA:3.20.140.10 311 389 2.8E-6 T 23-10-2018 A3L04_00090 623705ecd14b5a87a8a01f992e713005 389 PIRSF PIRSF000484 69 387 6.8E-51 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A3L04_00090 623705ecd14b5a87a8a01f992e713005 389 PIRSF PIRSF000484 9 71 2.6 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A3L04_00090 623705ecd14b5a87a8a01f992e713005 389 Gene3D G3DSA:3.20.20.70 106 296 1.9E-66 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_02295 12a4ba729b38c53224a8a9f404e8d044 116 SUPERFAMILY SSF88697 1 110 2.49E-29 T 23-10-2018 IPR015947 PUA-like superfamily A3L04_02295 12a4ba729b38c53224a8a9f404e8d044 116 Pfam PF04266 ASCH domain 6 97 2.5E-12 T 23-10-2018 IPR007374 ASCH domain A3L04_02295 12a4ba729b38c53224a8a9f404e8d044 116 Gene3D G3DSA:2.30.130.30 1 100 1.9E-32 T 23-10-2018 A3L04_02295 12a4ba729b38c53224a8a9f404e8d044 116 SMART SM01022 4 98 2.3E-5 T 23-10-2018 IPR007374 ASCH domain A3L04_03055 cad8925660d2deedc129b151570fa383 795 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 7 793 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 A3L04_03055 cad8925660d2deedc129b151570fa383 795 SUPERFAMILY SSF50692 2 91 1.53E-31 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L04_03055 cad8925660d2deedc129b151570fa383 795 Gene3D G3DSA:3.40.50.300 507 682 1.2E-74 T 23-10-2018 A3L04_03055 cad8925660d2deedc129b151570fa383 795 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 8 92 9.8E-36 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A3L04_03055 cad8925660d2deedc129b151570fa383 795 SMART SM01072 107 170 6.5E-19 T 23-10-2018 IPR004201 CDC48, domain 2 A3L04_03055 cad8925660d2deedc129b151570fa383 795 Gene3D G3DSA:1.10.8.60 684 792 4.6E-36 T 23-10-2018 A3L04_03055 cad8925660d2deedc129b151570fa383 795 Gene3D G3DSA:3.10.330.10 93 173 1.6E-8 T 23-10-2018 A3L04_03055 cad8925660d2deedc129b151570fa383 795 Gene3D G3DSA:1.10.8.60 414 505 1.7E-17 T 23-10-2018 A3L04_03055 cad8925660d2deedc129b151570fa383 795 SUPERFAMILY SSF52540 511 790 2.12E-80 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_03055 cad8925660d2deedc129b151570fa383 795 Gene3D G3DSA:1.10.8.60 350 371 1.7E-82 T 23-10-2018 A3L04_03055 cad8925660d2deedc129b151570fa383 795 SMART SM01073 8 92 3.2E-45 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A3L04_03055 cad8925660d2deedc129b151570fa383 795 SUPERFAMILY SSF54585 93 184 1.8E-21 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily A3L04_03055 cad8925660d2deedc129b151570fa383 795 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 107 169 1.2E-14 T 23-10-2018 IPR004201 CDC48, domain 2 A3L04_03055 cad8925660d2deedc129b151570fa383 795 Gene3D G3DSA:2.40.40.20 1 92 1.8E-37 T 23-10-2018 A3L04_03055 cad8925660d2deedc129b151570fa383 795 ProSitePatterns PS00674 AAA-protein family signature. 653 671 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L04_03055 cad8925660d2deedc129b151570fa383 795 Gene3D G3DSA:3.40.50.300 179 349 1.7E-82 T 23-10-2018 A3L04_03055 cad8925660d2deedc129b151570fa383 795 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 219 348 1.8E-51 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L04_03055 cad8925660d2deedc129b151570fa383 795 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 553 682 4.2E-48 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L04_03055 cad8925660d2deedc129b151570fa383 795 Pfam PF09336 Vps4 C terminal oligomerisation domain 749 785 1.3E-4 T 23-10-2018 IPR015415 Vps4 oligomerisation, C-terminal A3L04_03055 cad8925660d2deedc129b151570fa383 795 SUPERFAMILY SSF52540 179 502 1.09E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_03055 cad8925660d2deedc129b151570fa383 795 SMART SM00382 215 351 2.0E-25 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_03055 cad8925660d2deedc129b151570fa383 795 SMART SM00382 549 685 1.2E-23 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_03055 cad8925660d2deedc129b151570fa383 795 ProSitePatterns PS00674 AAA-protein family signature. 319 337 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L04_09090 eabd2110ae122ffcb56d1e148553ba68 534 Gene3D G3DSA:3.30.420.40 10 311 4.6E-67 T 23-10-2018 A3L04_09090 eabd2110ae122ffcb56d1e148553ba68 534 Pfam PF16861 Carbamoyltransferase C-terminus 363 532 1.9E-61 T 23-10-2018 IPR031730 Carbamoyltransferase, C-terminal A3L04_09090 eabd2110ae122ffcb56d1e148553ba68 534 SUPERFAMILY SSF53067 1 315 2.14E-15 T 23-10-2018 A3L04_09090 eabd2110ae122ffcb56d1e148553ba68 534 Gene3D G3DSA:3.30.420.350 96 304 4.6E-67 T 23-10-2018 A3L04_09090 eabd2110ae122ffcb56d1e148553ba68 534 Pfam PF02543 Carbamoyltransferase N-terminus 3 69 3.1E-9 T 23-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 A3L04_09090 eabd2110ae122ffcb56d1e148553ba68 534 Pfam PF02543 Carbamoyltransferase N-terminus 85 310 1.1E-39 T 23-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 A3L04_09090 eabd2110ae122ffcb56d1e148553ba68 534 Gene3D G3DSA:3.90.870.20 329 532 4.5E-71 T 23-10-2018 IPR038152 Carbamoyltransferase, C-terminal domain superfamily A3L04_01665 21c4ba87768a02b3fa88a02090741b36 356 SUPERFAMILY SSF103473 3 354 6.54E-49 T 23-10-2018 IPR036259 MFS transporter superfamily A3L04_01665 21c4ba87768a02b3fa88a02090741b36 356 Gene3D G3DSA:1.20.1250.20 1 171 6.6E-24 T 23-10-2018 A3L04_01665 21c4ba87768a02b3fa88a02090741b36 356 Pfam PF07690 Major Facilitator Superfamily 188 347 1.1E-14 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L04_01665 21c4ba87768a02b3fa88a02090741b36 356 Pfam PF07690 Major Facilitator Superfamily 3 162 1.7E-18 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L04_01665 21c4ba87768a02b3fa88a02090741b36 356 Gene3D G3DSA:1.20.1250.20 178 355 4.1E-19 T 23-10-2018 A3L04_04955 a08f9c308f2ff182ce3d7739bb8c178d 343 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 1 337 41.878 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 A3L04_04955 a08f9c308f2ff182ce3d7739bb8c178d 343 ProSitePatterns PS01287 RNA 3'-terminal phosphate cyclase signature. 154 164 - T 23-10-2018 IPR020719 RNA 3'-terminal phosphate cyclase-like, conserved site A3L04_04955 a08f9c308f2ff182ce3d7739bb8c178d 343 PIRSF PIRSF005378 1 341 1.9E-118 T 23-10-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 A3L04_04955 a08f9c308f2ff182ce3d7739bb8c178d 343 Gene3D G3DSA:3.30.360.20 182 275 6.3E-137 T 23-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily A3L04_04955 a08f9c308f2ff182ce3d7739bb8c178d 343 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 184 274 9.4E-25 T 23-10-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain A3L04_04955 a08f9c308f2ff182ce3d7739bb8c178d 343 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 2 324 6.9E-136 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 A3L04_04955 a08f9c308f2ff182ce3d7739bb8c178d 343 Gene3D G3DSA:3.65.10.20 4 320 6.3E-137 T 23-10-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily A3L04_04955 a08f9c308f2ff182ce3d7739bb8c178d 343 SUPERFAMILY SSF55205 1 226 2.09E-70 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A3L04_04955 a08f9c308f2ff182ce3d7739bb8c178d 343 Pfam PF01137 RNA 3'-terminal phosphate cyclase 8 325 1.6E-81 T 23-10-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain A3L04_09495 b14633187105f691fd8daca65c1891f8 335 Gene3D G3DSA:2.40.30.40 70 164 7.7E-113 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A3L04_09495 b14633187105f691fd8daca65c1891f8 335 SUPERFAMILY SSF53187 3 333 3.14E-49 T 23-10-2018 A3L04_09495 b14633187105f691fd8daca65c1891f8 335 Pfam PF05343 M42 glutamyl aminopeptidase 49 327 5.1E-72 T 23-10-2018 IPR008007 Peptidase M42 A3L04_09495 b14633187105f691fd8daca65c1891f8 335 Gene3D G3DSA:3.40.630.10 11 332 7.7E-113 T 23-10-2018 A3L04_09495 b14633187105f691fd8daca65c1891f8 335 SUPERFAMILY SSF101821 67 178 8.85E-26 T 23-10-2018 A3L04_09495 b14633187105f691fd8daca65c1891f8 335 PIRSF PIRSF001123 1 335 1.9E-38 T 23-10-2018 IPR008007 Peptidase M42 A3L04_06745 57a277c2493e47304abc10cf3784bfb1 356 SUPERFAMILY SSF100950 12 354 1.6E-111 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L04_06745 57a277c2493e47304abc10cf3784bfb1 356 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 42 342 1.9E-114 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L04_06745 57a277c2493e47304abc10cf3784bfb1 356 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 13 353 39.242 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L04_06745 57a277c2493e47304abc10cf3784bfb1 356 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 15 341 1.7E-126 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L04_06745 57a277c2493e47304abc10cf3784bfb1 356 Pfam PF01008 Initiation factor 2 subunit family 56 341 1.4E-79 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A3L04_06745 57a277c2493e47304abc10cf3784bfb1 356 Gene3D G3DSA:3.40.50.10470 145 343 8.0E-107 T 23-10-2018 A3L04_06745 57a277c2493e47304abc10cf3784bfb1 356 Gene3D G3DSA:1.20.120.420 47 144 8.0E-107 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L04_09255 52044e7f0f976633132b49fb7364e3e1 450 PRINTS PR00145 Argininosuccinate lyase family signature 227 251 6.2E-11 T 23-10-2018 A3L04_09255 52044e7f0f976633132b49fb7364e3e1 450 PRINTS PR00145 Argininosuccinate lyase family signature 136 156 6.2E-11 T 23-10-2018 A3L04_09255 52044e7f0f976633132b49fb7364e3e1 450 PRINTS PR00145 Argininosuccinate lyase family signature 95 117 6.2E-11 T 23-10-2018 A3L04_09255 52044e7f0f976633132b49fb7364e3e1 450 PRINTS PR00145 Argininosuccinate lyase family signature 272 288 6.2E-11 T 23-10-2018 A3L04_09255 52044e7f0f976633132b49fb7364e3e1 450 SUPERFAMILY SSF48557 4 445 5.18E-136 T 23-10-2018 IPR008948 L-Aspartase-like GO:0003824 A3L04_09255 52044e7f0f976633132b49fb7364e3e1 450 Gene3D G3DSA:1.10.40.30 359 448 2.0E-22 T 23-10-2018 A3L04_09255 52044e7f0f976633132b49fb7364e3e1 450 ProSitePatterns PS00163 Fumarate lyases signature. 272 281 - T 23-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A3L04_09255 52044e7f0f976633132b49fb7364e3e1 450 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 2.2E-26 T 23-10-2018 IPR000362 Fumarate lyase family A3L04_09255 52044e7f0f976633132b49fb7364e3e1 450 PRINTS PR00149 Fumarate lyase superfamily signature 272 288 2.2E-26 T 23-10-2018 IPR000362 Fumarate lyase family A3L04_09255 52044e7f0f976633132b49fb7364e3e1 450 PRINTS PR00149 Fumarate lyase superfamily signature 96 114 2.2E-26 T 23-10-2018 IPR000362 Fumarate lyase family A3L04_09255 52044e7f0f976633132b49fb7364e3e1 450 PRINTS PR00149 Fumarate lyase superfamily signature 227 254 2.2E-26 T 23-10-2018 IPR000362 Fumarate lyase family A3L04_09255 52044e7f0f976633132b49fb7364e3e1 450 Gene3D G3DSA:1.10.275.10 1 100 7.9E-38 T 23-10-2018 IPR024083 Fumarase/histidase, N-terminal A3L04_09255 52044e7f0f976633132b49fb7364e3e1 450 Pfam PF00206 Lyase 13 292 5.6E-59 T 23-10-2018 IPR022761 Fumarate lyase, N-terminal A3L04_09255 52044e7f0f976633132b49fb7364e3e1 450 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 6 439 4.3E-189 T 23-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L04_09255 52044e7f0f976633132b49fb7364e3e1 450 Gene3D G3DSA:1.20.200.10 101 358 2.0E-95 T 23-10-2018 A3L04_09255 52044e7f0f976633132b49fb7364e3e1 450 SMART SM00998 360 439 4.0E-29 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L04_09255 52044e7f0f976633132b49fb7364e3e1 450 Pfam PF10397 Adenylosuccinate lyase C-terminus 362 436 1.4E-18 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L04_08625 85ba1518a8ab5d7a1326ffc1017bb44b 367 Gene3D G3DSA:1.10.10.2140 315 367 2.2E-25 T 23-10-2018 A3L04_08625 85ba1518a8ab5d7a1326ffc1017bb44b 367 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 4 364 9.0E-135 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 A3L04_08625 85ba1518a8ab5d7a1326ffc1017bb44b 367 Gene3D G3DSA:3.40.50.11740 59 300 5.5E-112 T 23-10-2018 A3L04_08625 85ba1518a8ab5d7a1326ffc1017bb44b 367 Gene3D G3DSA:3.40.50.11750 15 260 5.5E-112 T 23-10-2018 A3L04_08625 85ba1518a8ab5d7a1326ffc1017bb44b 367 PIRSF PIRSF005622 1 367 8.1E-144 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 A3L04_08625 85ba1518a8ab5d7a1326ffc1017bb44b 367 Pfam PF01924 Hydrogenase formation hypA family 10 364 1.2E-137 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 A3L04_01870 9fb094da5c9f5254fcd8171869fd17ab 442 Pfam PF00156 Phosphoribosyl transferase domain 271 367 2.9E-9 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L04_01870 9fb094da5c9f5254fcd8171869fd17ab 442 SUPERFAMILY SSF56235 5 240 3.0E-56 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L04_01870 9fb094da5c9f5254fcd8171869fd17ab 442 Pfam PF13537 Glutamine amidotransferase domain 72 199 4.4E-19 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A3L04_01870 9fb094da5c9f5254fcd8171869fd17ab 442 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 5 436 6.4E-161 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A3L04_01870 9fb094da5c9f5254fcd8171869fd17ab 442 SUPERFAMILY SSF53271 233 438 3.67E-70 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L04_01870 9fb094da5c9f5254fcd8171869fd17ab 442 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 4 435 45.713 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A3L04_01870 9fb094da5c9f5254fcd8171869fd17ab 442 Gene3D G3DSA:3.60.20.10 5 436 5.9E-149 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L04_01870 9fb094da5c9f5254fcd8171869fd17ab 442 Gene3D G3DSA:3.40.50.2020 258 420 5.9E-149 T 23-10-2018 A3L04_01870 9fb094da5c9f5254fcd8171869fd17ab 442 PIRSF PIRSF000485 1 440 1.8E-159 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A3L04_03675 8f5708071088650cc191f236d7add75b 238 SUPERFAMILY SSF51366 1 224 1.33E-50 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L04_03675 8f5708071088650cc191f236d7add75b 238 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 226 29.548 T 23-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 A3L04_03675 8f5708071088650cc191f236d7add75b 238 Gene3D G3DSA:3.20.20.70 3 235 1.6E-66 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_03675 8f5708071088650cc191f236d7add75b 238 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 222 2.1E-71 T 23-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 A3L04_03675 8f5708071088650cc191f236d7add75b 238 Pfam PF00977 Histidine biosynthesis protein 3 218 5.1E-58 T 23-10-2018 IPR006062 Histidine biosynthesis GO:0000105 A3L04_10280 0a0b06091d750b9803415ede8ea07367 653 SUPERFAMILY SSF48310 240 651 3.53E-66 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L04_10280 0a0b06091d750b9803415ede8ea07367 653 Gene3D G3DSA:1.10.569.10 281 474 1.5E-12 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L04_10280 0a0b06091d750b9803415ede8ea07367 653 SUPERFAMILY SSF56228 3 230 2.09E-44 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L04_10280 0a0b06091d750b9803415ede8ea07367 653 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 5 226 4.8E-41 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L04_10280 0a0b06091d750b9803415ede8ea07367 653 Gene3D G3DSA:3.60.9.10 2 230 1.3E-25 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L04_10280 0a0b06091d750b9803415ede8ea07367 653 SMART SM00790 1 228 6.4E-71 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L04_10280 0a0b06091d750b9803415ede8ea07367 653 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 272 578 7.7E-17 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L04_05945 b90857f050e58c76309fc668be4d2b46 410 Gene3D G3DSA:1.20.1250.20 236 410 2.0E-26 T 23-10-2018 A3L04_05945 b90857f050e58c76309fc668be4d2b46 410 SUPERFAMILY SSF103473 22 408 3.4E-63 T 23-10-2018 IPR036259 MFS transporter superfamily A3L04_05945 b90857f050e58c76309fc668be4d2b46 410 Pfam PF07690 Major Facilitator Superfamily 33 272 1.8E-32 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L04_05945 b90857f050e58c76309fc668be4d2b46 410 Pfam PF00083 Sugar (and other) transporter 273 408 2.9E-7 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A3L04_05945 b90857f050e58c76309fc668be4d2b46 410 Gene3D G3DSA:1.20.1250.20 23 210 5.0E-31 T 23-10-2018 A3L04_03175 be99a97b4d4b45f2069de8e7a5f502e0 183 SUPERFAMILY SSF55154 1 177 3.27E-38 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 A3L04_03175 be99a97b4d4b45f2069de8e7a5f502e0 183 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 1 153 2.0E-75 T 23-10-2018 A3L04_03175 be99a97b4d4b45f2069de8e7a5f502e0 183 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 2 173 4.4E-47 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 A3L04_03175 be99a97b4d4b45f2069de8e7a5f502e0 183 Pfam PF01928 CYTH domain 1 164 1.5E-34 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A3L04_03175 be99a97b4d4b45f2069de8e7a5f502e0 183 SMART SM01118 1 175 2.0E-23 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A3L04_03175 be99a97b4d4b45f2069de8e7a5f502e0 183 Gene3D G3DSA:2.40.320.10 1 179 3.8E-59 T 23-10-2018 A3L04_00230 82fb224023bd0a7594f97dab599fd6a7 257 Gene3D G3DSA:3.40.50.300 1 215 1.5E-44 T 23-10-2018 A3L04_00230 82fb224023bd0a7594f97dab599fd6a7 257 SMART SM00382 26 222 5.1E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_00230 82fb224023bd0a7594f97dab599fd6a7 257 SUPERFAMILY SSF52540 2 210 8.44E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_00230 82fb224023bd0a7594f97dab599fd6a7 257 Pfam PF00005 ABC transporter 18 151 5.9E-20 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_05095 a755aa6ee74873477ea002e312ec9b8d 128 Gene3D G3DSA:1.10.260.40 10 75 6.1E-7 T 23-10-2018 A3L04_05095 a755aa6ee74873477ea002e312ec9b8d 128 SMART SM00530 20 76 3.0E-4 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L04_05095 a755aa6ee74873477ea002e312ec9b8d 128 Pfam PF01022 Bacterial regulatory protein, arsR family 17 52 1.4E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_05095 a755aa6ee74873477ea002e312ec9b8d 128 SUPERFAMILY SSF47413 14 54 2.7E-6 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L04_01740 e0f95b363c44d43a73e5a6237b9a3d9c 202 Pfam PF01914 MarC family integral membrane protein 4 194 2.8E-28 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A3L04_03440 d62fdb1c80f39615a4c2118351b27182 243 ProSitePatterns PS00528 Ribosomal protein S4e signature. 9 23 - T 23-10-2018 IPR018199 Ribosomal protein S4e, N-terminal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03440 d62fdb1c80f39615a4c2118351b27182 243 ProDom PD002667 RIBOSOMAL RIBONUCLEOPROTEIN RNA-BINDING 40S S4 S4 S4E 30S ISOFORM X 88 182 1.0E-48 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03440 d62fdb1c80f39615a4c2118351b27182 243 SMART SM00363 44 107 5.7E-9 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03440 d62fdb1c80f39615a4c2118351b27182 243 Pfam PF00900 Ribosomal family S4e 96 173 1.1E-23 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03440 d62fdb1c80f39615a4c2118351b27182 243 Hamap MF_00485 30S ribosomal protein S4e [rps4e]. 8 242 42.9 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03440 d62fdb1c80f39615a4c2118351b27182 243 Gene3D G3DSA:3.10.290.40 1 118 1.9E-49 T 23-10-2018 A3L04_03440 d62fdb1c80f39615a4c2118351b27182 243 Gene3D G3DSA:2.30.30.30 179 243 4.5E-18 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L04_03440 d62fdb1c80f39615a4c2118351b27182 243 Gene3D G3DSA:2.40.50.740 123 177 8.0E-17 T 23-10-2018 IPR038237 Ribosomal protein S4e, central domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03440 d62fdb1c80f39615a4c2118351b27182 243 PIRSF PIRSF002116 2 243 1.2E-100 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03440 d62fdb1c80f39615a4c2118351b27182 243 Pfam PF08071 RS4NT (NUC023) domain 4 40 3.0E-17 T 23-10-2018 IPR013843 Ribosomal protein S4e, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03440 d62fdb1c80f39615a4c2118351b27182 243 Pfam PF01479 S4 domain 45 91 1.0E-12 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03440 d62fdb1c80f39615a4c2118351b27182 243 SUPERFAMILY SSF55174 52 96 1.22E-6 T 23-10-2018 A3L04_03440 d62fdb1c80f39615a4c2118351b27182 243 SMART SM00739 178 205 0.0055 T 23-10-2018 IPR005824 KOW A3L04_08370 b6e5cb0f888cc78a8ff08b42c1223850 206 Gene3D G3DSA:2.20.25.420 7 61 1.5E-7 T 23-10-2018 A3L04_08370 b6e5cb0f888cc78a8ff08b42c1223850 206 SMART SM00709 16 176 1.2E-81 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 A3L04_08370 b6e5cb0f888cc78a8ff08b42c1223850 206 Pfam PF03367 ZPR1 zinc-finger domain 17 173 1.4E-38 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 A3L04_08370 b6e5cb0f888cc78a8ff08b42c1223850 206 TIGRFAM TIGR00340 zpr1_rel: zinc finger protein ZPR1 homolog 18 184 1.3E-73 T 23-10-2018 IPR004470 Zinc finger, ZPR1-type, subgroup GO:0008270 A3L04_08370 b6e5cb0f888cc78a8ff08b42c1223850 206 TIGRFAM TIGR00310 ZPR1_znf: ZPR1 zinc finger domain 17 198 1.1E-60 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 A3L04_08370 b6e5cb0f888cc78a8ff08b42c1223850 206 Gene3D G3DSA:2.60.120.1040 64 192 1.5E-21 T 23-10-2018 A3L04_05620 6b6d03db78646be37d883073f66852ae 253 SMART SM00382 26 208 9.8E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_05620 6b6d03db78646be37d883073f66852ae 253 Pfam PF00005 ABC transporter 18 161 2.6E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_05620 6b6d03db78646be37d883073f66852ae 253 Gene3D G3DSA:3.40.50.300 1 242 1.0E-65 T 23-10-2018 A3L04_05620 6b6d03db78646be37d883073f66852ae 253 SUPERFAMILY SSF52540 2 221 1.88E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01865 604a4958b6e657d1bd640aba61c7e06d 235 ProSitePatterns PS01058 SAICAR synthetase signature 2. 167 175 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L04_01865 604a4958b6e657d1bd640aba61c7e06d 235 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 229 32.407 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L04_01865 604a4958b6e657d1bd640aba61c7e06d 235 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 3 229 4.7E-76 T 23-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A3L04_01865 604a4958b6e657d1bd640aba61c7e06d 235 Gene3D G3DSA:3.30.200.20 17 227 6.5E-99 T 23-10-2018 A3L04_01865 604a4958b6e657d1bd640aba61c7e06d 235 Pfam PF01259 SAICAR synthetase 3 224 2.5E-70 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L04_01865 604a4958b6e657d1bd640aba61c7e06d 235 SUPERFAMILY SSF56104 3 231 2.26E-82 T 23-10-2018 A3L04_01865 604a4958b6e657d1bd640aba61c7e06d 235 Gene3D G3DSA:3.30.470.20 80 215 6.5E-99 T 23-10-2018 A3L04_01865 604a4958b6e657d1bd640aba61c7e06d 235 ProSitePatterns PS01057 SAICAR synthetase signature 1. 81 95 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L04_03655 60a9f610c17e684b23b50ceb5c79a64f 176 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 22 159 1.4E-39 T 23-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A3L04_03655 60a9f610c17e684b23b50ceb5c79a64f 176 Gene3D G3DSA:3.30.230.40 1 75 1.3E-22 T 23-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 A3L04_03655 60a9f610c17e684b23b50ceb5c79a64f 176 Gene3D G3DSA:3.30.230.40 76 176 8.5E-33 T 23-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 A3L04_03655 60a9f610c17e684b23b50ceb5c79a64f 176 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 141 153 - T 23-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A3L04_03655 60a9f610c17e684b23b50ceb5c79a64f 176 SUPERFAMILY SSF54211 75 164 5.94E-26 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L04_03655 60a9f610c17e684b23b50ceb5c79a64f 176 SUPERFAMILY SSF54211 2 73 1.26E-16 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L04_03195 fb80086a1b8b06bd58122441c8fc0ec5 424 Hamap MF_01892 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS [tiaS]. 3 422 36.45 T 23-10-2018 IPR024913 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS GO:0002101|GO:0016879 A3L04_03195 fb80086a1b8b06bd58122441c8fc0ec5 424 Gene3D G3DSA:3.90.600.20 156 251 7.7E-34 T 23-10-2018 A3L04_03195 fb80086a1b8b06bd58122441c8fc0ec5 424 Pfam PF01336 OB-fold nucleic acid binding domain 268 342 4.6E-10 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L04_03195 fb80086a1b8b06bd58122441c8fc0ec5 424 Pfam PF08489 Domain of unknown function (DUF1743) 140 253 1.0E-37 T 23-10-2018 IPR013696 Domain of unknown function DUF1743 A3L04_03195 fb80086a1b8b06bd58122441c8fc0ec5 424 Gene3D G3DSA:3.30.70.2200 1 155 2.3E-61 T 23-10-2018 A3L04_03195 fb80086a1b8b06bd58122441c8fc0ec5 424 SUPERFAMILY SSF50249 267 344 4.76E-5 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_03195 fb80086a1b8b06bd58122441c8fc0ec5 424 Gene3D G3DSA:2.40.50.1010 252 401 3.9E-42 T 23-10-2018 A3L04_04685 6e6987b1f92b015bbc500b797dd5dfc3 113 ProDom PD005579 INITIATION FACTOR TRANSLATION 1A BIOSYNTHESIS EUKARYOTIC EIF-1A AIF-1A EIF-4C 1A 43 100 1.0E-17 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A3L04_04685 6e6987b1f92b015bbc500b797dd5dfc3 113 TIGRFAM TIGR00523 eIF-1A: translation initiation factor eIF-1A 11 100 1.2E-32 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A3L04_04685 6e6987b1f92b015bbc500b797dd5dfc3 113 Hamap MF_00216 Translation initiation factor 1A [eif1a]. 7 101 27.777 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A3L04_04685 6e6987b1f92b015bbc500b797dd5dfc3 113 Pfam PF01176 Translation initiation factor 1A / IF-1 22 85 2.2E-22 T 23-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 A3L04_04685 6e6987b1f92b015bbc500b797dd5dfc3 113 ProSitePatterns PS01262 Eukaryotic initiation factor 1A signature. 31 53 - T 23-10-2018 IPR018104 Translation initiation factor 1A (eIF-1A), conserved site GO:0003743|GO:0006413 A3L04_04685 6e6987b1f92b015bbc500b797dd5dfc3 113 SMART SM00652 18 101 1.7E-43 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A3L04_04685 6e6987b1f92b015bbc500b797dd5dfc3 113 Gene3D G3DSA:2.40.50.140 1 113 4.0E-43 T 23-10-2018 A3L04_04685 6e6987b1f92b015bbc500b797dd5dfc3 113 SUPERFAMILY SSF50249 4 104 1.49E-31 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_08725 97469d404ea9e887e054c502599ccd13 187 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 177 37.187 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like A3L04_08725 97469d404ea9e887e054c502599ccd13 187 Pfam PF02441 Flavoprotein 1 156 1.1E-27 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A3L04_08725 97469d404ea9e887e054c502599ccd13 187 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 2 175 5.3E-69 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like A3L04_08725 97469d404ea9e887e054c502599ccd13 187 SUPERFAMILY SSF52507 1 176 4.06E-58 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A3L04_08725 97469d404ea9e887e054c502599ccd13 187 Gene3D G3DSA:3.40.50.1950 1 182 1.1E-73 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A3L04_01075 595c3e7bde6db68e8a4fac7fbb042bf9 1319 Pfam PF13604 AAA domain 849 1039 4.4E-11 T 23-10-2018 A3L04_01075 595c3e7bde6db68e8a4fac7fbb042bf9 1319 Pfam PF13087 AAA domain 1100 1271 1.2E-21 T 23-10-2018 A3L04_01075 595c3e7bde6db68e8a4fac7fbb042bf9 1319 Gene3D G3DSA:3.40.50.300 1107 1306 1.3E-33 T 23-10-2018 A3L04_01075 595c3e7bde6db68e8a4fac7fbb042bf9 1319 Gene3D G3DSA:3.40.50.300 795 1054 2.1E-25 T 23-10-2018 A3L04_01075 595c3e7bde6db68e8a4fac7fbb042bf9 1319 SUPERFAMILY SSF52540 847 1305 4.42E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_07700 451a12478921a48cf50faab0eefd4798 225 TIGRFAM TIGR02076 pyrH_arch: putative uridylate kinase 3 224 8.1E-87 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A3L04_07700 451a12478921a48cf50faab0eefd4798 225 SUPERFAMILY SSF53633 1 224 3.27E-48 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L04_07700 451a12478921a48cf50faab0eefd4798 225 Hamap MF_01220_A Uridylate kinase [pyrH]. 1 225 34.836 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A3L04_07700 451a12478921a48cf50faab0eefd4798 225 PIRSF PIRSF005650 1 225 7.0E-58 T 23-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A3L04_07700 451a12478921a48cf50faab0eefd4798 225 Gene3D G3DSA:3.40.1160.10 1 225 1.3E-60 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L04_07700 451a12478921a48cf50faab0eefd4798 225 Pfam PF00696 Amino acid kinase family 1 202 1.6E-27 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A3L04_06200 82981da5269911d81b8ef6e51ef311c9 295 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 30 281 2.0E-95 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 A3L04_06200 82981da5269911d81b8ef6e51ef311c9 295 ProSitePatterns PS01215 Mrp family signature. 146 162 - T 23-10-2018 IPR000808 Mrp, conserved site GO:0005524 A3L04_06200 82981da5269911d81b8ef6e51ef311c9 295 Gene3D G3DSA:3.40.50.300 17 280 1.3E-80 T 23-10-2018 A3L04_06200 82981da5269911d81b8ef6e51ef311c9 295 SUPERFAMILY SSF52540 18 265 5.43E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_06200 82981da5269911d81b8ef6e51ef311c9 295 Hamap MF_02040 Iron-sulfur cluster carrier protein. 20 282 36.902 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein A3L04_04020 c7b8a906e70394268ff3b3da6bb1872f 452 Gene3D G3DSA:3.40.1360.10 198 293 2.3E-12 T 23-10-2018 A3L04_04020 c7b8a906e70394268ff3b3da6bb1872f 452 SUPERFAMILY SSF56731 199 295 1.65E-10 T 23-10-2018 A3L04_04020 c7b8a906e70394268ff3b3da6bb1872f 452 Hamap MF_00007 DNA primase DnaG [dnaG]. 36 451 36.959 T 23-10-2018 IPR020607 DNA primase DnaG, archaea GO:0000178|GO:0003896|GO:0008143 A3L04_04020 c7b8a906e70394268ff3b3da6bb1872f 452 SMART SM00493 200 269 5.7E-12 T 23-10-2018 IPR006171 TOPRIM domain A3L04_04020 c7b8a906e70394268ff3b3da6bb1872f 452 Pfam PF13662 Toprim domain 201 284 5.0E-13 T 23-10-2018 IPR006171 TOPRIM domain A3L04_09580 beaa8f1e5b4d85278dd63528f51fbcfa 438 Gene3D G3DSA:3.30.470.20 189 328 3.6E-47 T 23-10-2018 A3L04_09580 beaa8f1e5b4d85278dd63528f51fbcfa 438 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 330 416 3.6E-13 T 23-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L04_09580 beaa8f1e5b4d85278dd63528f51fbcfa 438 SUPERFAMILY SSF56059 103 321 1.13E-48 T 23-10-2018 A3L04_09580 beaa8f1e5b4d85278dd63528f51fbcfa 438 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 290 297 - T 23-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L04_09580 beaa8f1e5b4d85278dd63528f51fbcfa 438 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 102 296 5.2E-61 T 23-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L04_09580 beaa8f1e5b4d85278dd63528f51fbcfa 438 SUPERFAMILY SSF52440 1 102 1.73E-26 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L04_09580 beaa8f1e5b4d85278dd63528f51fbcfa 438 SMART SM01209 102 296 1.6E-97 T 23-10-2018 A3L04_09580 beaa8f1e5b4d85278dd63528f51fbcfa 438 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 417 1.5E-152 T 23-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L04_09580 beaa8f1e5b4d85278dd63528f51fbcfa 438 Gene3D G3DSA:3.90.600.10 329 418 2.0E-9 T 23-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L04_09580 beaa8f1e5b4d85278dd63528f51fbcfa 438 SUPERFAMILY SSF51246 326 417 4.63E-17 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A3L04_09580 beaa8f1e5b4d85278dd63528f51fbcfa 438 Gene3D G3DSA:3.30.1490.20 122 187 5.0E-16 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L04_09580 beaa8f1e5b4d85278dd63528f51fbcfa 438 Gene3D G3DSA:3.40.50.20 2 94 3.4E-23 T 23-10-2018 A3L04_09580 beaa8f1e5b4d85278dd63528f51fbcfa 438 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 101 4.1E-24 T 23-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L04_09580 beaa8f1e5b4d85278dd63528f51fbcfa 438 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 418 36.931 T 23-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L04_09580 beaa8f1e5b4d85278dd63528f51fbcfa 438 SMART SM01210 328 418 6.7E-23 T 23-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L04_01100 1cc6a40f594742ffb07d4e491233f718 502 SUPERFAMILY SSF56300 1 234 1.9E-47 T 23-10-2018 A3L04_01100 1cc6a40f594742ffb07d4e491233f718 502 SUPERFAMILY SSF56300 268 484 3.0E-27 T 23-10-2018 A3L04_01100 1cc6a40f594742ffb07d4e491233f718 502 Gene3D G3DSA:3.60.21.10 1 251 3.9E-38 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L04_01100 1cc6a40f594742ffb07d4e491233f718 502 Gene3D G3DSA:3.60.21.10 262 491 5.2E-17 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L04_01100 1cc6a40f594742ffb07d4e491233f718 502 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 278 470 4.9E-9 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L04_01100 1cc6a40f594742ffb07d4e491233f718 502 Pfam PF00149 Calcineurin-like phosphoesterase 2 184 1.3E-17 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L04_05810 fc70cedfa1c8ab36c4222683b5748704 534 Gene3D G3DSA:3.20.20.70 5 327 3.7E-116 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_05810 fc70cedfa1c8ab36c4222683b5748704 534 SMART SM00917 376 518 1.1E-42 T 23-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A3L04_05810 fc70cedfa1c8ab36c4222683b5748704 534 SUPERFAMILY SSF51569 3 294 1.72E-86 T 23-10-2018 A3L04_05810 fc70cedfa1c8ab36c4222683b5748704 534 Gene3D G3DSA:3.30.160.270 399 517 2.2E-10 T 23-10-2018 A3L04_05810 fc70cedfa1c8ab36c4222683b5748704 534 SUPERFAMILY SSF110921 397 514 1.31E-23 T 23-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A3L04_05810 fc70cedfa1c8ab36c4222683b5748704 534 Pfam PF08502 LeuA allosteric (dimerisation) domain 377 516 4.2E-29 T 23-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A3L04_05810 fc70cedfa1c8ab36c4222683b5748704 534 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 6 521 3.1E-246 T 23-10-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 A3L04_05810 fc70cedfa1c8ab36c4222683b5748704 534 Pfam PF00682 HMGL-like 6 275 2.2E-48 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A3L04_05810 fc70cedfa1c8ab36c4222683b5748704 534 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 13 29 - T 23-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 Gene3D G3DSA:3.10.28.10 715 822 2.1E-25 T 23-10-2018 IPR027434 Homing endonuclease A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 SUPERFAMILY SSF51294 465 959 2.16E-37 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 937 959 8.4E-11 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 PRINTS PR00379 Intein signature 650 662 1.4E-19 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 PRINTS PR00379 Intein signature 547 560 1.4E-19 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 PRINTS PR00379 Intein signature 755 770 1.4E-19 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 PRINTS PR00379 Intein signature 935 952 1.4E-19 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 PRINTS PR00379 Intein signature 727 739 1.4E-19 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 467 560 8.6E-8 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 Pfam PF14528 LAGLIDADG-like domain 726 800 4.2E-15 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 Gene3D G3DSA:3.30.450.380 102 323 1.5E-66 T 23-10-2018 A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 Pfam PF00437 Type II/IV secretion system protein 229 461 1.5E-54 T 23-10-2018 IPR001482 Type II/IV secretion system protein A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 Gene3D G3DSA:3.40.50.300 959 1110 3.1E-34 T 23-10-2018 A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 Gene3D G3DSA:3.40.50.300 324 461 3.4E-59 T 23-10-2018 A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 SUPERFAMILY SSF55608 718 817 3.4E-21 T 23-10-2018 IPR027434 Homing endonuclease A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 SUPERFAMILY SSF52540 209 459 2.26E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 Gene3D G3DSA:2.170.16.10 462 608 8.0E-28 T 23-10-2018 A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 SMART SM00382 356 587 2.3E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 Pfam PF14890 Intein splicing domain 467 958 9.9E-32 T 23-10-2018 A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 SMART SM00306 458 584 3.3E-20 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 Gene3D G3DSA:2.170.16.10 886 958 6.5E-14 T 23-10-2018 A3L04_06010 365909680f4059e3f8a293ea529bcc6c 1123 SMART SM00305 914 964 2.7E-17 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L04_04480 1ab0597ad955e4173c27965b67fd34e8 570 Pfam PF03129 Anticodon binding domain 476 566 1.1E-23 T 23-10-2018 IPR004154 Anticodon-binding A3L04_04480 1ab0597ad955e4173c27965b67fd34e8 570 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 8 566 2.0E-220 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L04_04480 1ab0597ad955e4173c27965b67fd34e8 570 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 157 232 5.4E-10 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_04480 1ab0597ad955e4173c27965b67fd34e8 570 Hamap MF_00253_A Glycine--tRNA ligase [glyQS]. 6 569 47.335 T 23-10-2018 IPR022960 Glycine-tRNA ligase, archaeal GO:0004820 KEGG: 00970+6.1.1.14 A3L04_04480 1ab0597ad955e4173c27965b67fd34e8 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 27 41 1.7E-57 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L04_04480 1ab0597ad955e4173c27965b67fd34e8 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 193 210 1.7E-57 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L04_04480 1ab0597ad955e4173c27965b67fd34e8 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 435 447 1.7E-57 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L04_04480 1ab0597ad955e4173c27965b67fd34e8 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 210 220 1.7E-57 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L04_04480 1ab0597ad955e4173c27965b67fd34e8 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 514 533 1.7E-57 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L04_04480 1ab0597ad955e4173c27965b67fd34e8 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 142 154 1.7E-57 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L04_04480 1ab0597ad955e4173c27965b67fd34e8 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 161 178 1.7E-57 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L04_04480 1ab0597ad955e4173c27965b67fd34e8 570 Gene3D G3DSA:3.30.930.10 14 458 7.0E-143 T 23-10-2018 A3L04_04480 1ab0597ad955e4173c27965b67fd34e8 570 SUPERFAMILY SSF52954 463 568 6.95E-33 T 23-10-2018 A3L04_04480 1ab0597ad955e4173c27965b67fd34e8 570 SUPERFAMILY SSF55681 6 479 1.46E-119 T 23-10-2018 A3L04_04480 1ab0597ad955e4173c27965b67fd34e8 570 Gene3D G3DSA:3.40.50.800 474 570 1.6E-32 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A3L04_04480 1ab0597ad955e4173c27965b67fd34e8 570 Gene3D G3DSA:1.10.30.30 363 426 7.0E-143 T 23-10-2018 A3L04_04480 1ab0597ad955e4173c27965b67fd34e8 570 Gene3D G3DSA:1.20.1430.20 84 147 7.0E-143 T 23-10-2018 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 Gene3D G3DSA:2.170.16.10 673 732 5.3E-9 T 23-10-2018 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 Gene3D G3DSA:2.20.28.10 130 174 5.5E-25 T 23-10-2018 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 Pfam PF14890 Intein splicing domain 419 735 2.1E-23 T 23-10-2018 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 Gene3D G3DSA:2.170.16.10 415 545 1.2E-36 T 23-10-2018 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 Gene3D G3DSA:3.30.1640.10 1 98 1.0E-34 T 23-10-2018 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 SUPERFAMILY SSF52540 287 424 4.57E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 SUPERFAMILY SSF52540 734 919 1.1E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 Gene3D G3DSA:3.10.28.10 546 672 1.8E-11 T 23-10-2018 IPR027434 Homing endonuclease A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 Gene3D G3DSA:3.40.50.300 733 919 4.0E-71 T 23-10-2018 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 Gene3D G3DSA:3.40.50.300 261 414 9.3E-67 T 23-10-2018 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 Pfam PF17207 MCM OB domain 104 229 4.0E-33 T 23-10-2018 IPR033762 MCM OB domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 SMART SM00305 693 741 0.0026 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 714 736 2.7E-5 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 SUPERFAMILY SSF50249 9 245 1.08E-58 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 SUPERFAMILY SSF55608 609 669 9.07E-9 T 23-10-2018 IPR027434 Homing endonuclease A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 PRINTS PR00379 Intein signature 730 739 1.2E-7 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 PRINTS PR00379 Intein signature 625 637 1.2E-7 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 PRINTS PR00379 Intein signature 495 508 1.2E-7 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 PRINTS PR00379 Intein signature 712 729 1.2E-7 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 416 508 8.3E-15 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 Pfam PF00493 MCM2/3/5 family 734 914 3.6E-66 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 Pfam PF00493 MCM2/3/5 family 264 412 3.6E-65 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 Pfam PF14551 MCM N-terminal domain 8 96 2.3E-10 T 23-10-2018 IPR027925 MCM N-terminal domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 SMART SM00306 410 532 4.7E-23 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 SMART SM00350 99 916 4.4E-123 T 23-10-2018 IPR031327 Mini-chromosome maintenance protein A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 Gene3D G3DSA:2.40.50.140 175 255 5.0E-28 T 23-10-2018 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 Gene3D G3DSA:1.10.10.10 920 1003 1.0E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 754 766 1.8E-18 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 730 743 1.8E-18 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 781 789 1.8E-18 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 318 333 1.8E-18 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 SUPERFAMILY SSF51294 414 736 8.63E-33 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L04_09735 f4b03f69f3ba6a2f681e64680b777b58 1004 Pfam PF14528 LAGLIDADG-like domain 626 669 6.2E-5 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L04_04405 6b671f7e36c17dd236d727ba1a55ca27 341 Gene3D G3DSA:3.40.50.1100 65 338 8.7E-75 T 23-10-2018 A3L04_04405 6b671f7e36c17dd236d727ba1a55ca27 341 Gene3D G3DSA:3.40.50.1100 86 181 8.7E-75 T 23-10-2018 A3L04_04405 6b671f7e36c17dd236d727ba1a55ca27 341 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 64 338 2.8E-55 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L04_04405 6b671f7e36c17dd236d727ba1a55ca27 341 SUPERFAMILY SSF53686 2 338 3.14E-71 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L04_05790 4d5536545389eebddf85fc208c0ac3a6 498 SUPERFAMILY SSF110921 395 496 4.05E-24 T 23-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A3L04_05790 4d5536545389eebddf85fc208c0ac3a6 498 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 1 498 44.347 T 23-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A3L04_05790 4d5536545389eebddf85fc208c0ac3a6 498 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 23-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A3L04_05790 4d5536545389eebddf85fc208c0ac3a6 498 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 3 494 1.2E-227 T 23-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A3L04_05790 4d5536545389eebddf85fc208c0ac3a6 498 Pfam PF00682 HMGL-like 3 272 6.9E-103 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A3L04_05790 4d5536545389eebddf85fc208c0ac3a6 498 Gene3D G3DSA:1.10.238.260 279 390 1.8E-39 T 23-10-2018 A3L04_05790 4d5536545389eebddf85fc208c0ac3a6 498 Pfam PF08502 LeuA allosteric (dimerisation) domain 369 496 2.2E-34 T 23-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A3L04_05790 4d5536545389eebddf85fc208c0ac3a6 498 SUPERFAMILY SSF51569 2 290 9.23E-104 T 23-10-2018 A3L04_05790 4d5536545389eebddf85fc208c0ac3a6 498 Gene3D G3DSA:3.20.20.70 1 275 1.7E-117 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_05790 4d5536545389eebddf85fc208c0ac3a6 498 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 198 211 - T 23-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A3L04_05790 4d5536545389eebddf85fc208c0ac3a6 498 Gene3D G3DSA:3.30.160.270 391 498 4.8E-11 T 23-10-2018 A3L04_05790 4d5536545389eebddf85fc208c0ac3a6 498 SMART SM00917 368 497 5.7E-39 T 23-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A3L04_04425 e40473b585bd35e97d368f8c080f08e5 559 Hamap MF_00407 DNA ligase [lig]. 1 550 34.46 T 23-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 A3L04_04425 e40473b585bd35e97d368f8c080f08e5 559 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 57 550 5.2E-174 T 23-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 A3L04_04425 e40473b585bd35e97d368f8c080f08e5 559 SUPERFAMILY SSF117018 2 242 2.22E-70 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 A3L04_04425 e40473b585bd35e97d368f8c080f08e5 559 Pfam PF04675 DNA ligase N terminus 3 176 3.9E-39 T 23-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 A3L04_04425 e40473b585bd35e97d368f8c080f08e5 559 Gene3D G3DSA:2.40.50.140 422 559 2.0E-54 T 23-10-2018 A3L04_04425 e40473b585bd35e97d368f8c080f08e5 559 Pfam PF01068 ATP dependent DNA ligase domain 224 422 1.9E-67 T 23-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 A3L04_04425 e40473b585bd35e97d368f8c080f08e5 559 Pfam PF04679 ATP dependent DNA ligase C terminal region 443 534 1.1E-23 T 23-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 A3L04_04425 e40473b585bd35e97d368f8c080f08e5 559 Gene3D G3DSA:1.10.3260.10 1 220 2.9E-81 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 A3L04_04425 e40473b585bd35e97d368f8c080f08e5 559 SUPERFAMILY SSF50249 426 552 1.83E-42 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_04425 e40473b585bd35e97d368f8c080f08e5 559 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 398 422 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 A3L04_04425 e40473b585bd35e97d368f8c080f08e5 559 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 247 255 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 A3L04_04425 e40473b585bd35e97d368f8c080f08e5 559 SUPERFAMILY SSF56091 219 422 5.04E-55 T 23-10-2018 A3L04_04425 e40473b585bd35e97d368f8c080f08e5 559 Gene3D G3DSA:3.30.470.30 221 421 2.2E-73 T 23-10-2018 A3L04_10325 bbffba2e49c044e2d291bd9732dd3636 219 Gene3D G3DSA:3.30.200.20 9 87 3.1E-26 T 23-10-2018 A3L04_10325 bbffba2e49c044e2d291bd9732dd3636 219 Pfam PF01163 RIO1 family 41 146 3.1E-16 T 23-10-2018 A3L04_10325 bbffba2e49c044e2d291bd9732dd3636 219 TIGRFAM TIGR03724 arch_bud32: Kae1-associated kinase Bud32 3 212 5.5E-76 T 23-10-2018 IPR022495 Serine/threonine-protein kinase Bud32 GO:0004674 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 A3L04_10325 bbffba2e49c044e2d291bd9732dd3636 219 SMART SM00220 1 218 1.4E-4 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A3L04_10325 bbffba2e49c044e2d291bd9732dd3636 219 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 123 135 - T 23-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 A3L04_10325 bbffba2e49c044e2d291bd9732dd3636 219 Gene3D G3DSA:1.10.510.10 96 214 4.5E-34 T 23-10-2018 A3L04_10325 bbffba2e49c044e2d291bd9732dd3636 219 SUPERFAMILY SSF56112 2 156 2.43E-30 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A3L04_00720 4d0ec247900bd7436de777bac0c59d5c 403 Gene3D G3DSA:1.10.287.660 131 243 4.2E-39 T 23-10-2018 IPR029012 Helix hairpin bin domain superfamily A3L04_00720 4d0ec247900bd7436de777bac0c59d5c 403 SUPERFAMILY SSF89124 126 366 2.22E-80 T 23-10-2018 IPR036070 Nop domain superfamily A3L04_00720 4d0ec247900bd7436de777bac0c59d5c 403 Gene3D G3DSA:1.10.246.90 244 368 1.8E-52 T 23-10-2018 A3L04_00720 4d0ec247900bd7436de777bac0c59d5c 403 Gene3D G3DSA:3.30.420.220 1 125 2.4E-53 T 23-10-2018 A3L04_00720 4d0ec247900bd7436de777bac0c59d5c 403 Gene3D G3DSA:1.10.150.460 161 212 4.2E-39 T 23-10-2018 A3L04_00720 4d0ec247900bd7436de777bac0c59d5c 403 Pfam PF01798 snoRNA binding domain, fibrillarin 138 363 1.7E-73 T 23-10-2018 IPR002687 Nop domain A3L04_00720 4d0ec247900bd7436de777bac0c59d5c 403 SMART SM00931 130 182 2.8E-27 T 23-10-2018 IPR012976 NOSIC A3L04_02240 78f5c8945c53a6e7a89588c1c48357d4 257 Gene3D G3DSA:3.90.1640.20 1 256 2.3E-78 T 23-10-2018 A3L04_02240 78f5c8945c53a6e7a89588c1c48357d4 257 Pfam PF14336 Domain of unknown function (DUF4392) 2 249 1.3E-55 T 23-10-2018 IPR025504 Domain of unknown function DUF4392 KEGG: 00471+4.2.1.48 A3L04_00235 507853362dfb577ba4aac4ce86e40330 756 Gene3D G3DSA:1.10.150.20 683 756 3.3E-24 T 23-10-2018 A3L04_00235 507853362dfb577ba4aac4ce86e40330 756 Gene3D G3DSA:3.40.50.300 1 199 5.4E-77 T 23-10-2018 A3L04_00235 507853362dfb577ba4aac4ce86e40330 756 Pfam PF00271 Helicase conserved C-terminal domain 346 463 1.3E-23 T 23-10-2018 IPR001650 Helicase, C-terminal A3L04_00235 507853362dfb577ba4aac4ce86e40330 756 SMART SM00891 545 625 3.2E-30 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 A3L04_00235 507853362dfb577ba4aac4ce86e40330 756 Pfam PF04851 Type III restriction enzyme, res subunit 21 166 8.2E-20 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A3L04_00235 507853362dfb577ba4aac4ce86e40330 756 SMART SM00487 6 201 1.7E-33 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L04_00235 507853362dfb577ba4aac4ce86e40330 756 Gene3D G3DSA:3.40.50.300 209 481 4.3E-105 T 23-10-2018 A3L04_00235 507853362dfb577ba4aac4ce86e40330 756 SMART SM00278 728 747 0.046 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L04_00235 507853362dfb577ba4aac4ce86e40330 756 SMART SM00278 696 715 730.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L04_00235 507853362dfb577ba4aac4ce86e40330 756 SMART SM00490 375 464 7.8E-24 T 23-10-2018 IPR001650 Helicase, C-terminal A3L04_00235 507853362dfb577ba4aac4ce86e40330 756 Pfam PF02732 ERCC4 domain 548 665 2.9E-30 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 A3L04_00235 507853362dfb577ba4aac4ce86e40330 756 SUPERFAMILY SSF52980 545 673 4.29E-40 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L04_00235 507853362dfb577ba4aac4ce86e40330 756 Gene3D G3DSA:3.40.50.10130 541 682 1.6E-56 T 23-10-2018 A3L04_00235 507853362dfb577ba4aac4ce86e40330 756 SUPERFAMILY SSF52540 52 483 6.32E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_00235 507853362dfb577ba4aac4ce86e40330 756 SUPERFAMILY SSF47781 683 753 3.71E-16 T 23-10-2018 IPR010994 RuvA domain 2-like A3L04_00235 507853362dfb577ba4aac4ce86e40330 756 Pfam PF12826 Helix-hairpin-helix motif 700 749 9.1E-11 T 23-10-2018 A3L04_00235 507853362dfb577ba4aac4ce86e40330 756 Gene3D G3DSA:1.20.1320.20 212 341 4.3E-105 T 23-10-2018 A3L04_04855 70ad29a16012ae6b31f8213fc9784b8b 311 Gene3D G3DSA:3.40.50.150 103 310 6.6E-72 T 23-10-2018 A3L04_04855 70ad29a16012ae6b31f8213fc9784b8b 311 Gene3D G3DSA:3.30.70.3130 2 99 1.3E-18 T 23-10-2018 A3L04_04855 70ad29a16012ae6b31f8213fc9784b8b 311 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 39 309 1.7E-91 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L04_04855 70ad29a16012ae6b31f8213fc9784b8b 311 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 14 100 1.3E-14 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L04_04855 70ad29a16012ae6b31f8213fc9784b8b 311 Pfam PF01189 16S rRNA methyltransferase RsmB/F 104 307 2.4E-52 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L04_04855 70ad29a16012ae6b31f8213fc9784b8b 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 231 247 3.6E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_04855 70ad29a16012ae6b31f8213fc9784b8b 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 292 309 3.6E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_04855 70ad29a16012ae6b31f8213fc9784b8b 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 86 100 3.6E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_04855 70ad29a16012ae6b31f8213fc9784b8b 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 181 193 3.6E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_04855 70ad29a16012ae6b31f8213fc9784b8b 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 115 125 3.6E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_04855 70ad29a16012ae6b31f8213fc9784b8b 311 SUPERFAMILY SSF53335 21 309 1.07E-64 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_06845 af32849cc276f8de42cf8b11eb92a716 620 SUPERFAMILY SSF53474 368 614 5.15E-52 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L04_06845 af32849cc276f8de42cf8b11eb92a716 620 Gene3D G3DSA:3.40.50.1820 2 610 4.4E-143 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L04_06845 af32849cc276f8de42cf8b11eb92a716 620 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 2 351 3.8E-24 T 23-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 A3L04_06845 af32849cc276f8de42cf8b11eb92a716 620 SUPERFAMILY SSF50993 2 351 1.33E-44 T 23-10-2018 A3L04_06845 af32849cc276f8de42cf8b11eb92a716 620 Pfam PF00326 Prolyl oligopeptidase family 412 614 1.9E-56 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A3L04_06845 af32849cc276f8de42cf8b11eb92a716 620 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 548 570 1.1E-53 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L04_06845 af32849cc276f8de42cf8b11eb92a716 620 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 449 468 1.1E-53 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L04_06845 af32849cc276f8de42cf8b11eb92a716 620 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 395 413 1.1E-53 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L04_06845 af32849cc276f8de42cf8b11eb92a716 620 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 530 545 1.1E-53 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L04_06845 af32849cc276f8de42cf8b11eb92a716 620 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 475 495 1.1E-53 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L04_06845 af32849cc276f8de42cf8b11eb92a716 620 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 421 445 1.1E-53 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L04_06845 af32849cc276f8de42cf8b11eb92a716 620 Gene3D G3DSA:2.130.10.120 49 362 4.4E-143 T 23-10-2018 A3L04_05890 575a327ac44d80753024a29e86e7a489 185 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 10 178 1.4E-44 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L04_05890 575a327ac44d80753024a29e86e7a489 185 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 1 181 5.5E-81 T 23-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 A3L04_05890 575a327ac44d80753024a29e86e7a489 185 Gene3D G3DSA:3.40.920.10 1 183 1.7E-73 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L04_05890 575a327ac44d80753024a29e86e7a489 185 SUPERFAMILY SSF53323 1 180 6.28E-58 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L04_08595 f729028e038fd7272997de0f68dfb8b1 237 SUPERFAMILY SSF56770 2 212 1.96E-46 T 23-10-2018 A3L04_08595 f729028e038fd7272997de0f68dfb8b1 237 Gene3D G3DSA:3.40.50.700 1 161 1.2E-39 T 23-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily A3L04_08595 f729028e038fd7272997de0f68dfb8b1 237 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 11 146 7.4E-27 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07875 901418c58136dbbbf223f44056cc6485 428 SUPERFAMILY SSF50465 321 424 8.63E-39 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A3L04_07875 901418c58136dbbbf223f44056cc6485 428 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 59 74 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site A3L04_07875 901418c58136dbbbf223f44056cc6485 428 Pfam PF03143 Elongation factor Tu C-terminal domain 318 424 7.5E-37 T 23-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal A3L04_07875 901418c58136dbbbf223f44056cc6485 428 Gene3D G3DSA:2.40.30.10 315 425 1.2E-40 T 23-10-2018 A3L04_07875 901418c58136dbbbf223f44056cc6485 428 Hamap MF_00118_A Elongation factor Tu [tuf]. 2 427 61.943 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 A3L04_07875 901418c58136dbbbf223f44056cc6485 428 PRINTS PR00315 GTP-binding elongation factor signature 66 74 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_07875 901418c58136dbbbf223f44056cc6485 428 PRINTS PR00315 GTP-binding elongation factor signature 102 113 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_07875 901418c58136dbbbf223f44056cc6485 428 PRINTS PR00315 GTP-binding elongation factor signature 86 96 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_07875 901418c58136dbbbf223f44056cc6485 428 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_07875 901418c58136dbbbf223f44056cc6485 428 PRINTS PR00315 GTP-binding elongation factor signature 139 148 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_07875 901418c58136dbbbf223f44056cc6485 428 SUPERFAMILY SSF50447 213 315 7.07E-30 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L04_07875 901418c58136dbbbf223f44056cc6485 428 SUPERFAMILY SSF52540 3 236 4.46E-78 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_07875 901418c58136dbbbf223f44056cc6485 428 Pfam PF03144 Elongation factor Tu domain 2 235 306 2.6E-17 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A3L04_07875 901418c58136dbbbf223f44056cc6485 428 TIGRFAM TIGR00483 EF-1_alpha: translation elongation factor EF-1, subunit alpha 1 426 3.8E-214 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 A3L04_07875 901418c58136dbbbf223f44056cc6485 428 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 190 3.7E-17 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L04_07875 901418c58136dbbbf223f44056cc6485 428 Gene3D G3DSA:3.40.50.300 1 212 5.3E-90 T 23-10-2018 A3L04_07875 901418c58136dbbbf223f44056cc6485 428 Gene3D G3DSA:2.40.30.10 216 310 1.7E-42 T 23-10-2018 A3L04_07875 901418c58136dbbbf223f44056cc6485 428 Pfam PF00009 Elongation factor Tu GTP binding domain 5 209 1.6E-60 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_05370 43f4b3b485099966806be65f30a96e42 419 Gene3D G3DSA:3.90.220.20 13 227 7.4E-41 T 23-10-2018 A3L04_05370 43f4b3b485099966806be65f30a96e42 419 Gene3D G3DSA:3.90.220.20 229 419 2.2E-42 T 23-10-2018 A3L04_05370 43f4b3b485099966806be65f30a96e42 419 SUPERFAMILY SSF116734 22 221 4.09E-35 T 23-10-2018 A3L04_05370 43f4b3b485099966806be65f30a96e42 419 Pfam PF01420 Type I restriction modification DNA specificity domain 231 404 2.6E-14 T 23-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A3L04_05370 43f4b3b485099966806be65f30a96e42 419 Pfam PF01420 Type I restriction modification DNA specificity domain 33 203 3.6E-14 T 23-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A3L04_05370 43f4b3b485099966806be65f30a96e42 419 SUPERFAMILY SSF116734 230 419 4.74E-39 T 23-10-2018 A3L04_08005 8d0511e9f6b3c65686220c3886d2a093 682 SMART SM00926 2 58 1.0E-10 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_08005 8d0511e9f6b3c65686220c3886d2a093 682 Pfam PF01568 Molydopterin dinucleotide binding domain 569 672 1.4E-33 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A3L04_08005 8d0511e9f6b3c65686220c3886d2a093 682 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 5 55 4.8E-10 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_08005 8d0511e9f6b3c65686220c3886d2a093 682 SUPERFAMILY SSF50692 532 678 2.49E-47 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L04_08005 8d0511e9f6b3c65686220c3886d2a093 682 Gene3D G3DSA:2.40.40.20 558 681 2.6E-41 T 23-10-2018 A3L04_08005 8d0511e9f6b3c65686220c3886d2a093 682 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 7 676 5.2E-204 T 23-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 A3L04_08005 8d0511e9f6b3c65686220c3886d2a093 682 Gene3D G3DSA:2.20.25.90 1 63 4.2E-12 T 23-10-2018 A3L04_08005 8d0511e9f6b3c65686220c3886d2a093 682 Gene3D G3DSA:3.40.228.10 138 337 3.3E-162 T 23-10-2018 A3L04_08005 8d0511e9f6b3c65686220c3886d2a093 682 Pfam PF00384 Molybdopterin oxidoreductase 61 481 5.2E-89 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_08005 8d0511e9f6b3c65686220c3886d2a093 682 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 427 444 - T 23-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A3L04_08005 8d0511e9f6b3c65686220c3886d2a093 682 SUPERFAMILY SSF53706 3 571 4.19E-190 T 23-10-2018 A3L04_08005 8d0511e9f6b3c65686220c3886d2a093 682 Gene3D G3DSA:3.40.50.740 66 527 3.3E-162 T 23-10-2018 A3L04_09355 56bfbb3b3be8cb88e94a78daf47a4c4c 720 SUPERFAMILY SSF158702 492 701 8.11E-60 T 23-10-2018 A3L04_09355 56bfbb3b3be8cb88e94a78daf47a4c4c 720 Gene3D G3DSA:3.40.50.300 8 200 4.2E-78 T 23-10-2018 A3L04_09355 56bfbb3b3be8cb88e94a78daf47a4c4c 720 Pfam PF00271 Helicase conserved C-terminal domain 233 372 1.1E-8 T 23-10-2018 IPR001650 Helicase, C-terminal A3L04_09355 56bfbb3b3be8cb88e94a78daf47a4c4c 720 SUPERFAMILY SSF52540 36 386 4.56E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09355 56bfbb3b3be8cb88e94a78daf47a4c4c 720 SMART SM00490 287 373 1.3E-16 T 23-10-2018 IPR001650 Helicase, C-terminal A3L04_09355 56bfbb3b3be8cb88e94a78daf47a4c4c 720 SMART SM00487 20 204 3.1E-33 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L04_09355 56bfbb3b3be8cb88e94a78daf47a4c4c 720 Gene3D G3DSA:3.40.50.300 201 398 9.3E-61 T 23-10-2018 A3L04_09355 56bfbb3b3be8cb88e94a78daf47a4c4c 720 SUPERFAMILY SSF46785 404 491 2.99E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_09355 56bfbb3b3be8cb88e94a78daf47a4c4c 720 Hamap MF_00442 ATP-dependent DNA helicase Hel308 [hel308]. 9 701 30.89 T 23-10-2018 IPR022965 ATP-dependent DNA helicase Hel308 GO:0004386 A3L04_09355 56bfbb3b3be8cb88e94a78daf47a4c4c 720 Gene3D G3DSA:1.10.150.20 644 700 1.0E-24 T 23-10-2018 A3L04_09355 56bfbb3b3be8cb88e94a78daf47a4c4c 720 Pfam PF14520 Helix-hairpin-helix domain 648 699 4.8E-11 T 23-10-2018 A3L04_09355 56bfbb3b3be8cb88e94a78daf47a4c4c 720 SMART SM00278 679 698 0.004 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L04_09355 56bfbb3b3be8cb88e94a78daf47a4c4c 720 SMART SM00278 646 665 0.74 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L04_09355 56bfbb3b3be8cb88e94a78daf47a4c4c 720 Pfam PF00270 DEAD/DEAH box helicase 26 180 1.4E-28 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L04_09355 56bfbb3b3be8cb88e94a78daf47a4c4c 720 Gene3D G3DSA:1.10.3380.30 410 642 1.6E-79 T 23-10-2018 A3L04_06030 61961267e8e82bba55960021447236d7 355 Gene3D G3DSA:3.40.50.300 5 160 6.6E-44 T 23-10-2018 A3L04_06030 61961267e8e82bba55960021447236d7 355 SUPERFAMILY SSF52540 4 166 4.97E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_06030 61961267e8e82bba55960021447236d7 355 Pfam PF01926 50S ribosome-binding GTPase 105 160 5.7E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_06030 61961267e8e82bba55960021447236d7 355 Gene3D G3DSA:1.10.1580.10 168 250 1.4E-14 T 23-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily A3L04_00085 76b1f37573309d7ab5a77bddbf2034c4 143 Gene3D G3DSA:3.40.50.360 1 136 4.6E-16 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A3L04_00085 76b1f37573309d7ab5a77bddbf2034c4 143 SUPERFAMILY SSF52218 1 136 1.01E-17 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A3L04_00085 76b1f37573309d7ab5a77bddbf2034c4 143 Pfam PF12724 Flavodoxin domain 1 86 8.1E-16 T 23-10-2018 IPR026816 Flavodoxin domain A3L04_00085 76b1f37573309d7ab5a77bddbf2034c4 143 ProSitePatterns PS00201 Flavodoxin signature. 2 18 - T 23-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 A3L04_04465 6b5a53d53d819ab42539927cb7e8ee4f 230 PIRSF PIRSF000883 1 230 6.3E-74 T 23-10-2018 IPR011152 Phosphoesterase MJ0912 A3L04_04465 6b5a53d53d819ab42539927cb7e8ee4f 230 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 193 4.7E-30 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L04_04465 6b5a53d53d819ab42539927cb7e8ee4f 230 Gene3D G3DSA:3.60.21.10 2 230 1.8E-73 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L04_04465 6b5a53d53d819ab42539927cb7e8ee4f 230 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 194 1.7E-17 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A3L04_04465 6b5a53d53d819ab42539927cb7e8ee4f 230 SUPERFAMILY SSF56300 1 230 3.49E-67 T 23-10-2018 A3L04_10780 97f9e80004e61f162728d89a6ca3a8fd 169 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 75 88 - T 23-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 A3L04_10780 97f9e80004e61f162728d89a6ca3a8fd 169 SMART SM00852 17 163 7.6E-27 T 23-10-2018 IPR001453 MoaB/Mog domain A3L04_10780 97f9e80004e61f162728d89a6ca3a8fd 169 Gene3D G3DSA:3.40.980.10 10 169 2.5E-48 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L04_10780 97f9e80004e61f162728d89a6ca3a8fd 169 PIRSF PIRSF006443 1 169 4.4E-54 T 23-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 A3L04_10780 97f9e80004e61f162728d89a6ca3a8fd 169 SUPERFAMILY SSF53218 13 167 4.58E-39 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L04_10780 97f9e80004e61f162728d89a6ca3a8fd 169 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 15 157 2.5E-32 T 23-10-2018 IPR001453 MoaB/Mog domain A3L04_10780 97f9e80004e61f162728d89a6ca3a8fd 169 Pfam PF00994 Probable molybdopterin binding domain 17 158 1.0E-33 T 23-10-2018 IPR001453 MoaB/Mog domain A3L04_09480 62f9d4b88f6c91b183d6b5216ea2d313 148 SUPERFAMILY SSF52374 7 142 1.18E-26 T 23-10-2018 A3L04_09480 62f9d4b88f6c91b183d6b5216ea2d313 148 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 8 74 4.1E-21 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L04_09480 62f9d4b88f6c91b183d6b5216ea2d313 148 Hamap MF_02115 FAD synthase [ribL]. 7 147 29.979 T 23-10-2018 IPR024902 FAD synthase RibL GO:0003919|GO:0006747|GO:0046444 KEGG: 00740+2.7.7.2|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L04_09480 62f9d4b88f6c91b183d6b5216ea2d313 148 Gene3D G3DSA:3.40.50.620 1 146 1.5E-41 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_09480 62f9d4b88f6c91b183d6b5216ea2d313 148 Pfam PF01467 Cytidylyltransferase-like 10 141 1.2E-25 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L04_07155 b91460d85ea95c8b400551c98a0e375b 333 SUPERFAMILY SSF52440 2 98 9.59E-33 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L04_07155 b91460d85ea95c8b400551c98a0e375b 333 Pfam PF06849 Protein of unknown function (DUF1246) 4 118 2.9E-35 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L04_07155 b91460d85ea95c8b400551c98a0e375b 333 Gene3D G3DSA:3.30.1490.20 115 176 2.0E-102 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L04_07155 b91460d85ea95c8b400551c98a0e375b 333 Gene3D G3DSA:3.40.50.20 1 86 1.0E-30 T 23-10-2018 A3L04_07155 b91460d85ea95c8b400551c98a0e375b 333 Gene3D G3DSA:3.30.470.20 88 332 2.0E-102 T 23-10-2018 A3L04_07155 b91460d85ea95c8b400551c98a0e375b 333 Pfam PF06973 Domain of unknown function (DUF1297) 149 333 9.4E-75 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L04_07155 b91460d85ea95c8b400551c98a0e375b 333 Hamap MF_01163 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [purP]. 2 333 50.233 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L04_07155 b91460d85ea95c8b400551c98a0e375b 333 PIRSF PIRSF004602 1 333 2.9E-136 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L04_07155 b91460d85ea95c8b400551c98a0e375b 333 SUPERFAMILY SSF56059 102 333 1.03E-79 T 23-10-2018 A3L04_00695 39483aaccc5db9df66ab63d693ac63f9 109 Gene3D G3DSA:1.10.10.10 2 109 2.7E-34 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_00695 39483aaccc5db9df66ab63d693ac63f9 109 SUPERFAMILY SSF46785 7 104 4.57E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_00695 39483aaccc5db9df66ab63d693ac63f9 109 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 14 85 1.6E-11 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L04_09085 c8e740a9d0d36bcecd9aa281809c22e0 270 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 42 234 1.0E-49 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L04_09085 c8e740a9d0d36bcecd9aa281809c22e0 270 PIRSF PIRSF005054 1 239 6.4E-73 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L04_09085 c8e740a9d0d36bcecd9aa281809c22e0 270 Gene3D G3DSA:3.30.70.1900 123 237 4.8E-40 T 23-10-2018 A3L04_09085 c8e740a9d0d36bcecd9aa281809c22e0 270 Gene3D G3DSA:3.30.70.1890 1 122 7.5E-46 T 23-10-2018 A3L04_09085 c8e740a9d0d36bcecd9aa281809c22e0 270 Pfam PF01881 CRISPR associated protein Cas6 95 235 2.0E-32 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L04_03840 b0e14ae060d137d6ade6e8898e010b35 334 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 329 58.872 T 23-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A3L04_03840 b0e14ae060d137d6ade6e8898e010b35 334 SUPERFAMILY SSF56796 8 330 4.58E-88 T 23-10-2018 A3L04_03840 b0e14ae060d137d6ade6e8898e010b35 334 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 21 327 3.0E-102 T 23-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A3L04_03840 b0e14ae060d137d6ade6e8898e010b35 334 Gene3D G3DSA:3.40.50.1970 3 156 8.7E-50 T 23-10-2018 A3L04_03840 b0e14ae060d137d6ade6e8898e010b35 334 Pfam PF01761 3-dehydroquinate synthase 52 299 7.1E-88 T 23-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A3L04_03840 b0e14ae060d137d6ade6e8898e010b35 334 Gene3D G3DSA:1.20.1090.10 157 333 2.1E-48 T 23-10-2018 A3L04_03840 b0e14ae060d137d6ade6e8898e010b35 334 PIRSF PIRSF001455 5 333 1.4E-99 T 23-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A3L04_01945 1f9b992572ef4125a7adc4978ad8d5a6 175 TIGRFAM TIGR00725 TIGR00725: TIGR00725 family protein 1 163 1.4E-53 T 23-10-2018 IPR005268 Conserved hypothetical protein CHP00725 A3L04_01945 1f9b992572ef4125a7adc4978ad8d5a6 175 Pfam PF03641 Possible lysine decarboxylase 44 160 1.2E-5 T 23-10-2018 IPR031100 LOG family A3L04_01945 1f9b992572ef4125a7adc4978ad8d5a6 175 SUPERFAMILY SSF102405 1 162 2.9E-34 T 23-10-2018 A3L04_01945 1f9b992572ef4125a7adc4978ad8d5a6 175 Gene3D G3DSA:3.40.50.450 1 165 2.4E-33 T 23-10-2018 A3L04_08425 a4d4e796abb9e417ef113c258e7ef3fe 359 Pfam PF00557 Metallopeptidase family M24 149 350 5.5E-30 T 23-10-2018 IPR000994 Peptidase M24 A3L04_08425 a4d4e796abb9e417ef113c258e7ef3fe 359 Pfam PF01321 Creatinase/Prolidase N-terminal domain 11 142 2.7E-12 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 A3L04_08425 a4d4e796abb9e417ef113c258e7ef3fe 359 SUPERFAMILY SSF55920 141 358 1.11E-41 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like A3L04_08425 a4d4e796abb9e417ef113c258e7ef3fe 359 Gene3D G3DSA:3.40.350.10 8 142 1.2E-20 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L04_08425 a4d4e796abb9e417ef113c258e7ef3fe 359 Gene3D G3DSA:3.90.230.10 143 359 3.5E-40 T 23-10-2018 A3L04_08425 a4d4e796abb9e417ef113c258e7ef3fe 359 SUPERFAMILY SSF53092 3 141 6.15E-24 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L04_02205 1041774f9f5fa98173a37415a0f1a6d6 94 Hamap MF_01476 50S ribosomal protein L44e [rpl44e]. 1 92 25.365 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_02205 1041774f9f5fa98173a37415a0f1a6d6 94 ProSitePatterns PS01172 Ribosomal protein L44e signature. 60 71 - T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_02205 1041774f9f5fa98173a37415a0f1a6d6 94 SUPERFAMILY SSF57829 1 93 9.16E-32 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L04_02205 1041774f9f5fa98173a37415a0f1a6d6 94 ProDom PD002841 RIBOSOMAL RIBONUCLEOPROTEIN 60S L44 L44E L41 RESISTANCE 50S ANTIBIOTIC CYCLOHEXIMIDE 9 93 4.0E-41 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_02205 1041774f9f5fa98173a37415a0f1a6d6 94 Pfam PF00935 Ribosomal protein L44 16 92 1.4E-26 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_02205 1041774f9f5fa98173a37415a0f1a6d6 94 Gene3D G3DSA:3.10.450.80 1 93 2.4E-32 T 23-10-2018 A3L04_07760 ae541b5c933cda5ee3dd76a93a919081 212 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 10 212 5.9E-42 T 23-10-2018 IPR002727 Protein of unknown function DUF47 A3L04_07760 ae541b5c933cda5ee3dd76a93a919081 212 Pfam PF01865 Protein of unknown function DUF47 5 209 5.8E-43 T 23-10-2018 IPR018445 Putative phosphate transport regulator A3L04_07760 ae541b5c933cda5ee3dd76a93a919081 212 SUPERFAMILY SSF109755 28 207 6.45E-10 T 23-10-2018 A3L04_07760 ae541b5c933cda5ee3dd76a93a919081 212 Gene3D G3DSA:1.20.58.220 4 210 4.0E-47 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L04_05365 5b741e266d29244a6318c84e3b3e1787 502 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 275 287 2.4E-18 T 23-10-2018 A3L04_05365 5b741e266d29244a6318c84e3b3e1787 502 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 193 207 2.4E-18 T 23-10-2018 A3L04_05365 5b741e266d29244a6318c84e3b3e1787 502 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 169 185 2.4E-18 T 23-10-2018 A3L04_05365 5b741e266d29244a6318c84e3b3e1787 502 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 302 326 2.4E-18 T 23-10-2018 A3L04_05365 5b741e266d29244a6318c84e3b3e1787 502 Gene3D G3DSA:1.20.1260.30 1 142 9.3E-34 T 23-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily A3L04_05365 5b741e266d29244a6318c84e3b3e1787 502 SUPERFAMILY SSF53335 5 500 1.45E-112 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_05365 5b741e266d29244a6318c84e3b3e1787 502 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 278 284 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A3L04_05365 5b741e266d29244a6318c84e3b3e1787 502 Gene3D G3DSA:3.40.50.150 144 470 2.7E-74 T 23-10-2018 A3L04_05365 5b741e266d29244a6318c84e3b3e1787 502 Pfam PF12161 HsdM N-terminal domain 8 132 1.7E-9 T 23-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain A3L04_05365 5b741e266d29244a6318c84e3b3e1787 502 Pfam PF02384 N-6 DNA Methylase 146 464 7.0E-63 T 23-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A3L04_00410 9a553cb45c08fd691378d4955636238f 61 Gene3D G3DSA:1.20.5.820 1 61 1.5E-28 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L04_00410 9a553cb45c08fd691378d4955636238f 61 Hamap MF_00422 Protein translocase subunit SecE [secE]. 6 61 12.1 T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L04_00410 9a553cb45c08fd691378d4955636238f 61 TIGRFAM TIGR00327 secE_euk_arch: protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic 6 56 2.1E-19 T 23-10-2018 IPR008158 Protein translocase SEC61 complex, gamma subunit GO:0015031|GO:0015450|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L04_00410 9a553cb45c08fd691378d4955636238f 61 SUPERFAMILY SSF103456 4 57 9.02E-21 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L04_00410 9a553cb45c08fd691378d4955636238f 61 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 11 39 - T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L04_01805 1bd94a3c23b7e3af7b88a62307e6e350 196 SUPERFAMILY SSF53323 2 191 2.09E-27 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L04_01805 1bd94a3c23b7e3af7b88a62307e6e350 196 Gene3D G3DSA:3.40.920.10 1 196 5.0E-36 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L04_01805 1bd94a3c23b7e3af7b88a62307e6e350 196 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 190 9.4E-35 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L04_04220 a7589377c75d34f8be563b01666f3ec7 89 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 70 81 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_04220 a7589377c75d34f8be563b01666f3ec7 89 SUPERFAMILY SSF54862 23 87 1.01E-15 T 23-10-2018 A3L04_04220 a7589377c75d34f8be563b01666f3ec7 89 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 33 44 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_04220 a7589377c75d34f8be563b01666f3ec7 89 Gene3D G3DSA:3.30.70.20 2 89 2.3E-16 T 23-10-2018 A3L04_04220 a7589377c75d34f8be563b01666f3ec7 89 Pfam PF12838 4Fe-4S dicluster domain 33 81 5.6E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L04_04160 a401871dcdbf32423736fa2021752b4f 198 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 67 83 - T 23-10-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site MetaCyc: PWY-7942 A3L04_04160 a401871dcdbf32423736fa2021752b4f 198 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 128 142 - T 23-10-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site MetaCyc: PWY-7942 A3L04_04160 a401871dcdbf32423736fa2021752b4f 198 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 78 98 2.9E-41 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L04_04160 a401871dcdbf32423736fa2021752b4f 198 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 130 146 2.9E-41 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L04_04160 a401871dcdbf32423736fa2021752b4f 198 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 3 26 2.9E-41 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L04_04160 a401871dcdbf32423736fa2021752b4f 198 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 160 172 2.9E-41 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L04_04160 a401871dcdbf32423736fa2021752b4f 198 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 60 72 2.9E-41 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L04_04160 a401871dcdbf32423736fa2021752b4f 198 Pfam PF01470 Pyroglutamyl peptidase 1 197 4.5E-79 T 23-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 A3L04_04160 a401871dcdbf32423736fa2021752b4f 198 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 1 198 38.424 T 23-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 A3L04_04160 a401871dcdbf32423736fa2021752b4f 198 SUPERFAMILY SSF53182 1 197 5.76E-72 T 23-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 A3L04_04160 a401871dcdbf32423736fa2021752b4f 198 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 2 196 1.6E-75 T 23-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 A3L04_04160 a401871dcdbf32423736fa2021752b4f 198 PIRSF PIRSF015592 1 198 3.9E-81 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L04_04160 a401871dcdbf32423736fa2021752b4f 198 Gene3D G3DSA:3.40.630.20 1 198 6.1E-78 T 23-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 A3L04_06125 f30b1fb9028a2730e5ee8c13d2cea8b7 440 SUPERFAMILY SSF55424 319 437 1.27E-29 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A3L04_06125 f30b1fb9028a2730e5ee8c13d2cea8b7 440 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 325 426 5.2E-19 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A3L04_06125 f30b1fb9028a2730e5ee8c13d2cea8b7 440 Gene3D G3DSA:3.50.50.60 319 440 1.6E-44 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_06125 f30b1fb9028a2730e5ee8c13d2cea8b7 440 Gene3D G3DSA:3.50.50.60 42 240 2.9E-118 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_06125 f30b1fb9028a2730e5ee8c13d2cea8b7 440 Gene3D G3DSA:3.50.50.60 3 313 2.9E-118 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_06125 f30b1fb9028a2730e5ee8c13d2cea8b7 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 4.7E-22 T 23-10-2018 A3L04_06125 f30b1fb9028a2730e5ee8c13d2cea8b7 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 383 398 4.7E-22 T 23-10-2018 A3L04_06125 f30b1fb9028a2730e5ee8c13d2cea8b7 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 148 173 4.7E-22 T 23-10-2018 A3L04_06125 f30b1fb9028a2730e5ee8c13d2cea8b7 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 273 280 4.7E-22 T 23-10-2018 A3L04_06125 f30b1fb9028a2730e5ee8c13d2cea8b7 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 232 246 4.7E-22 T 23-10-2018 A3L04_06125 f30b1fb9028a2730e5ee8c13d2cea8b7 440 SUPERFAMILY SSF51905 1 343 3.69E-50 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_06125 f30b1fb9028a2730e5ee8c13d2cea8b7 440 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 302 4.5E-61 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L04_06125 f30b1fb9028a2730e5ee8c13d2cea8b7 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 3.1E-29 T 23-10-2018 A3L04_06125 f30b1fb9028a2730e5ee8c13d2cea8b7 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.1E-29 T 23-10-2018 A3L04_06125 f30b1fb9028a2730e5ee8c13d2cea8b7 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 3.1E-29 T 23-10-2018 A3L04_06125 f30b1fb9028a2730e5ee8c13d2cea8b7 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 3.1E-29 T 23-10-2018 A3L04_06125 f30b1fb9028a2730e5ee8c13d2cea8b7 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 3.1E-29 T 23-10-2018 A3L04_06125 f30b1fb9028a2730e5ee8c13d2cea8b7 440 TIGRFAM TIGR03385 CoA_CoA_reduc: CoA-disulfide reductase 3 435 3.0E-185 T 23-10-2018 IPR017758 Coenzyme A disulphide reductase GO:0003756|GO:0050451|GO:0050660|GO:0050661|GO:0055114 A3L04_05780 671bd9f9457a678237e496be33654be4 564 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 195 329 1.1E-47 T 23-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A3L04_05780 671bd9f9457a678237e496be33654be4 564 Gene3D G3DSA:3.40.50.970 367 563 1.2E-69 T 23-10-2018 A3L04_05780 671bd9f9457a678237e496be33654be4 564 SUPERFAMILY SSF52518 1 171 6.41E-63 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L04_05780 671bd9f9457a678237e496be33654be4 564 Gene3D G3DSA:3.40.50.1220 189 366 6.4E-59 T 23-10-2018 A3L04_05780 671bd9f9457a678237e496be33654be4 564 SUPERFAMILY SSF52518 369 561 4.18E-70 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L04_05780 671bd9f9457a678237e496be33654be4 564 SUPERFAMILY SSF52467 190 357 5.51E-54 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A3L04_05780 671bd9f9457a678237e496be33654be4 564 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 428 447 - T 23-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A3L04_05780 671bd9f9457a678237e496be33654be4 564 Gene3D G3DSA:3.40.50.970 1 181 1.1E-71 T 23-10-2018 A3L04_05780 671bd9f9457a678237e496be33654be4 564 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 3 562 6.0E-221 T 23-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A3L04_05780 671bd9f9457a678237e496be33654be4 564 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 167 2.0E-59 T 23-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A3L04_05780 671bd9f9457a678237e496be33654be4 564 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 392 539 7.8E-52 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L04_08990 acd86503093fd7afe8a6e683f7d38478 309 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 5 301 1.6E-12 T 23-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A3L04_08990 acd86503093fd7afe8a6e683f7d38478 309 Gene3D G3DSA:3.20.20.210 4 307 1.3E-49 T 23-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A3L04_08990 acd86503093fd7afe8a6e683f7d38478 309 SUPERFAMILY SSF51726 6 303 4.45E-48 T 23-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A3L04_04345 f6c572afd94829677f4d2d699db6ff2a 180 Pfam PF01479 S4 domain 103 148 3.1E-17 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_04345 f6c572afd94829677f4d2d699db6ff2a 180 SUPERFAMILY SSF55174 9 160 1.18E-34 T 23-10-2018 A3L04_04345 f6c572afd94829677f4d2d699db6ff2a 180 Gene3D G3DSA:3.10.290.10 102 176 4.1E-18 T 23-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A3L04_04345 f6c572afd94829677f4d2d699db6ff2a 180 ProSitePatterns PS00632 Ribosomal protein S4 signature. 101 125 - T 23-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_04345 f6c572afd94829677f4d2d699db6ff2a 180 SMART SM01390 5 102 1.3E-7 T 23-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A3L04_04345 f6c572afd94829677f4d2d699db6ff2a 180 Hamap MF_01306_A 30S ribosomal protein S4 [rpsD]. 1 156 34.52 T 23-10-2018 IPR022802 Ribosomal protein S4, archaeal GO:0006412|GO:0019843 A3L04_04345 f6c572afd94829677f4d2d699db6ff2a 180 TIGRFAM TIGR01018 uS4_arch: ribosomal protein uS4 1 161 7.0E-78 T 23-10-2018 IPR005710 Ribosomal protein S4/S9, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_04345 f6c572afd94829677f4d2d699db6ff2a 180 SMART SM00363 103 165 3.4E-15 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_09330 0eec6b1517d3039b2b132e3658db1ea0 432 Gene3D G3DSA:3.40.50.720 169 432 2.6E-91 T 23-10-2018 A3L04_09330 0eec6b1517d3039b2b132e3658db1ea0 432 Pfam PF03949 Malic enzyme, NAD binding domain 173 374 2.6E-24 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A3L04_09330 0eec6b1517d3039b2b132e3658db1ea0 432 SMART SM01274 27 159 7.7E-77 T 23-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A3L04_09330 0eec6b1517d3039b2b132e3658db1ea0 432 SMART SM00919 171 393 5.1E-126 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A3L04_09330 0eec6b1517d3039b2b132e3658db1ea0 432 Pfam PF00390 Malic enzyme, N-terminal domain 28 159 8.1E-29 T 23-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A3L04_09330 0eec6b1517d3039b2b132e3658db1ea0 432 Gene3D G3DSA:3.40.50.10380 11 168 2.8E-68 T 23-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 A3L04_09330 0eec6b1517d3039b2b132e3658db1ea0 432 ProSitePatterns PS00331 Malic enzymes signature. 167 183 - T 23-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 A3L04_09330 0eec6b1517d3039b2b132e3658db1ea0 432 SUPERFAMILY SSF51735 171 417 2.03E-81 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_09330 0eec6b1517d3039b2b132e3658db1ea0 432 PIRSF PIRSF000106 48 423 2.1E-90 T 23-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A3L04_09330 0eec6b1517d3039b2b132e3658db1ea0 432 SUPERFAMILY SSF53223 23 169 3.96E-54 T 23-10-2018 A3L04_09195 902615e7e5a007dfc71a434f5a6eba48 481 Pfam PF13186 Iron-sulfur cluster-binding domain 340 400 1.6E-7 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A3L04_09195 902615e7e5a007dfc71a434f5a6eba48 481 Gene3D G3DSA:3.20.20.70 91 441 5.6E-72 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_09195 902615e7e5a007dfc71a434f5a6eba48 481 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 340 425 5.7E-16 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A3L04_09195 902615e7e5a007dfc71a434f5a6eba48 481 Pfam PF13353 4Fe-4S single cluster domain 96 213 3.9E-11 T 23-10-2018 A3L04_09195 902615e7e5a007dfc71a434f5a6eba48 481 SUPERFAMILY SSF102114 92 406 1.07E-50 T 23-10-2018 A3L04_09195 902615e7e5a007dfc71a434f5a6eba48 481 SMART SM00729 88 308 5.7E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L04_09195 902615e7e5a007dfc71a434f5a6eba48 481 Pfam PF04055 Radical SAM superfamily 93 260 3.3E-16 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_10150 3deb4f7c052ef7b9de17aa9d593d3939 352 Pfam PF01637 ATPase domain predominantly from Archaea 14 240 1.6E-16 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_10150 3deb4f7c052ef7b9de17aa9d593d3939 352 Gene3D G3DSA:3.40.50.300 1 201 2.0E-38 T 23-10-2018 A3L04_10150 3deb4f7c052ef7b9de17aa9d593d3939 352 SUPERFAMILY SSF52540 3 281 2.18E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_10150 3deb4f7c052ef7b9de17aa9d593d3939 352 SUPERFAMILY SSF46785 280 350 3.35E-21 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_10150 3deb4f7c052ef7b9de17aa9d593d3939 352 Gene3D G3DSA:1.10.10.10 282 351 7.3E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_10150 3deb4f7c052ef7b9de17aa9d593d3939 352 Gene3D G3DSA:1.10.8.60 203 280 5.8E-27 T 23-10-2018 A3L04_04640 125942ca9ddae6601ccf6827560fa8de 241 Hamap MF_02040 Iron-sulfur cluster carrier protein. 11 235 27.381 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein A3L04_04640 125942ca9ddae6601ccf6827560fa8de 241 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 15 226 2.9E-54 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 A3L04_04640 125942ca9ddae6601ccf6827560fa8de 241 Gene3D G3DSA:3.40.50.300 1 223 3.1E-65 T 23-10-2018 A3L04_04640 125942ca9ddae6601ccf6827560fa8de 241 SUPERFAMILY SSF52540 14 215 2.2E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_00890 ff486960825b6073c9ba09e445042ad2 447 Pfam PF13692 Glycosyl transferases group 1 251 398 2.3E-25 T 23-10-2018 A3L04_00890 ff486960825b6073c9ba09e445042ad2 447 SUPERFAMILY SSF53756 1 436 7.85E-90 T 23-10-2018 A3L04_00890 ff486960825b6073c9ba09e445042ad2 447 Gene3D G3DSA:3.40.50.2000 2 435 1.0E-126 T 23-10-2018 A3L04_00890 ff486960825b6073c9ba09e445042ad2 447 Pfam PF08323 Starch synthase catalytic domain 2 199 3.3E-33 T 23-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 A3L04_00890 ff486960825b6073c9ba09e445042ad2 447 Gene3D G3DSA:3.40.50.2000 219 425 1.0E-126 T 23-10-2018 A3L04_09295 d0706e61a62c44c957c37e67d3a80b19 421 SUPERFAMILY SSF52283 5 421 9.64E-104 T 23-10-2018 A3L04_09295 d0706e61a62c44c957c37e67d3a80b19 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 6 138 1.0E-34 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L04_09295 d0706e61a62c44c957c37e67d3a80b19 421 Gene3D G3DSA:3.40.50.1480 9 410 4.4E-178 T 23-10-2018 A3L04_09295 d0706e61a62c44c957c37e67d3a80b19 421 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 2 421 51.216 T 23-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 A3L04_09295 d0706e61a62c44c957c37e67d3a80b19 421 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 210 226 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L04_09295 d0706e61a62c44c957c37e67d3a80b19 421 SMART SM00997 188 349 6.8E-112 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L04_09295 d0706e61a62c44c957c37e67d3a80b19 421 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 188 348 1.1E-50 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L04_09295 d0706e61a62c44c957c37e67d3a80b19 421 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 7 421 7.6E-215 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L04_09295 d0706e61a62c44c957c37e67d3a80b19 421 Gene3D G3DSA:3.40.50.720 190 349 4.4E-178 T 23-10-2018 A3L04_09295 d0706e61a62c44c957c37e67d3a80b19 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 141 416 1.3E-28 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L04_09295 d0706e61a62c44c957c37e67d3a80b19 421 SMART SM00996 6 420 7.3E-144 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L04_09295 d0706e61a62c44c957c37e67d3a80b19 421 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 78 92 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L04_09295 d0706e61a62c44c957c37e67d3a80b19 421 SUPERFAMILY SSF51735 188 350 6.61E-69 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_09295 d0706e61a62c44c957c37e67d3a80b19 421 PIRSF PIRSF001109 1 421 2.3E-199 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L04_02310 f550b3f0f192f39eaa0c9b68e0e794d1 102 Gene3D G3DSA:3.30.720.70 1 102 5.0E-49 T 23-10-2018 A3L04_05515 22ee5f49bc069a1b702422b6895da452 127 Gene3D G3DSA:1.20.120.330 1 119 1.3E-31 T 23-10-2018 A3L04_05515 22ee5f49bc069a1b702422b6895da452 127 Pfam PF05168 HEPN domain 3 115 4.4E-22 T 23-10-2018 IPR007842 HEPN domain A3L04_05515 22ee5f49bc069a1b702422b6895da452 127 SUPERFAMILY SSF81593 4 117 3.1E-7 T 23-10-2018 A3L04_03455 ef94fdba5b7b56c91a18e2240a57ac6b 130 Hamap MF_01302_A 30S ribosomal protein S8 [rpsH]. 2 130 38.963 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03455 ef94fdba5b7b56c91a18e2240a57ac6b 130 Gene3D G3DSA:3.30.1370.30 1 69 1.8E-33 T 23-10-2018 A3L04_03455 ef94fdba5b7b56c91a18e2240a57ac6b 130 SUPERFAMILY SSF56047 3 130 1.1E-40 T 23-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03455 ef94fdba5b7b56c91a18e2240a57ac6b 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03455 ef94fdba5b7b56c91a18e2240a57ac6b 130 Pfam PF00410 Ribosomal protein S8 5 130 1.3E-27 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03455 ef94fdba5b7b56c91a18e2240a57ac6b 130 Gene3D G3DSA:3.30.1490.10 70 128 3.0E-28 T 23-10-2018 A3L04_01315 51447bfa7ab2e6962787033f1ce81f63 509 TIGRFAM TIGR00284 TIGR00284: dihydropteroate synthase-related protein 1 494 1.9E-99 T 23-10-2018 IPR005236 Dihydropteroate synthase-related protein synthase-related protein A3L04_01315 51447bfa7ab2e6962787033f1ce81f63 509 Gene3D G3DSA:3.20.20.20 160 318 8.5E-11 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L04_01315 51447bfa7ab2e6962787033f1ce81f63 509 Pfam PF00809 Pterin binding enzyme 166 293 3.1E-9 T 23-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L04_01315 51447bfa7ab2e6962787033f1ce81f63 509 SUPERFAMILY SSF51717 138 359 6.28E-32 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L04_07145 6ebb30d6b523dcd5acb64d07d59d698d 142 Pfam PF13635 Domain of unknown function (DUF4143) 2 82 8.3E-12 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 A3L04_07765 fed0b8d57f9502812bfff51d63ad01a3 304 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 219 235 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A3L04_07765 fed0b8d57f9502812bfff51d63ad01a3 304 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 280 1.6E-73 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A3L04_07765 fed0b8d57f9502812bfff51d63ad01a3 304 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 190 212 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A3L04_07765 fed0b8d57f9502812bfff51d63ad01a3 304 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 304 7.4E-41 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A3L04_07765 fed0b8d57f9502812bfff51d63ad01a3 304 SUPERFAMILY SSF52283 1 133 1.66E-39 T 23-10-2018 A3L04_07765 fed0b8d57f9502812bfff51d63ad01a3 304 SUPERFAMILY SSF51735 99 281 2.82E-68 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_07765 fed0b8d57f9502812bfff51d63ad01a3 304 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 142 169 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A3L04_07765 fed0b8d57f9502812bfff51d63ad01a3 304 Gene3D G3DSA:3.40.50.720 7 298 6.9E-137 T 23-10-2018 A3L04_07765 fed0b8d57f9502812bfff51d63ad01a3 304 Gene3D G3DSA:3.40.50.720 92 282 6.9E-137 T 23-10-2018 A3L04_03800 2d5faf71789514efc07f68d6af1360ae 330 Gene3D G3DSA:3.40.50.720 5 315 1.9E-102 T 23-10-2018 A3L04_03800 2d5faf71789514efc07f68d6af1360ae 330 SUPERFAMILY SSF51735 1 157 8.36E-50 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_03800 2d5faf71789514efc07f68d6af1360ae 330 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 137 153 - T 23-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A3L04_03800 2d5faf71789514efc07f68d6af1360ae 330 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 134 1.5E-29 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A3L04_03800 2d5faf71789514efc07f68d6af1360ae 330 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 329 3.2E-115 T 23-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A3L04_03800 2d5faf71789514efc07f68d6af1360ae 330 SUPERFAMILY SSF55347 142 297 1.44E-31 T 23-10-2018 A3L04_03800 2d5faf71789514efc07f68d6af1360ae 330 SMART SM00859 3 134 4.9E-50 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A3L04_03800 2d5faf71789514efc07f68d6af1360ae 330 Gene3D G3DSA:3.30.360.10 140 301 1.9E-102 T 23-10-2018 A3L04_03800 2d5faf71789514efc07f68d6af1360ae 330 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 323 39.06 T 23-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A3L04_03970 65e9aed7fbb6cffa710aeeffc502127d 264 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 256 26.648 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A3L04_03970 65e9aed7fbb6cffa710aeeffc502127d 264 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 254 6.7E-80 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A3L04_03970 65e9aed7fbb6cffa710aeeffc502127d 264 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 152 254 4.0E-36 T 23-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A3L04_03970 65e9aed7fbb6cffa710aeeffc502127d 264 SUPERFAMILY SSF48179 151 257 9.69E-35 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A3L04_03970 65e9aed7fbb6cffa710aeeffc502127d 264 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 91 1.2E-20 T 23-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal A3L04_03970 65e9aed7fbb6cffa710aeeffc502127d 264 SUPERFAMILY SSF51735 2 150 8.92E-34 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_03970 65e9aed7fbb6cffa710aeeffc502127d 264 Gene3D G3DSA:3.40.50.720 1 154 3.0E-47 T 23-10-2018 A3L04_03970 65e9aed7fbb6cffa710aeeffc502127d 264 Gene3D G3DSA:1.10.3730.10 155 258 2.4E-36 T 23-10-2018 A3L04_03970 65e9aed7fbb6cffa710aeeffc502127d 264 PIRSF PIRSF000193 1 259 1.3E-75 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A3L04_03495 1efb66053ace5af99f8d2feda7658986 468 PRINTS PR00303 Preprotein translocase SecY subunit signature 170 193 1.0E-9 T 23-10-2018 A3L04_03495 1efb66053ace5af99f8d2feda7658986 468 PRINTS PR00303 Preprotein translocase SecY subunit signature 432 450 1.0E-9 T 23-10-2018 A3L04_03495 1efb66053ace5af99f8d2feda7658986 468 PRINTS PR00303 Preprotein translocase SecY subunit signature 30 48 1.0E-9 T 23-10-2018 A3L04_03495 1efb66053ace5af99f8d2feda7658986 468 PRINTS PR00303 Preprotein translocase SecY subunit signature 144 169 1.0E-9 T 23-10-2018 A3L04_03495 1efb66053ace5af99f8d2feda7658986 468 Pfam PF00344 SecY translocase 72 447 6.0E-71 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L04_03495 1efb66053ace5af99f8d2feda7658986 468 PIRSF PIRSF004557 5 467 1.2E-105 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L04_03495 1efb66053ace5af99f8d2feda7658986 468 SUPERFAMILY SSF103491 6 454 4.05E-110 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L04_03495 1efb66053ace5af99f8d2feda7658986 468 ProSitePatterns PS00755 Protein secY signature 1. 72 91 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L04_03495 1efb66053ace5af99f8d2feda7658986 468 ProSitePatterns PS00756 Protein secY signature 2. 163 180 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L04_03495 1efb66053ace5af99f8d2feda7658986 468 Gene3D G3DSA:1.10.3370.10 26 468 3.5E-194 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L04_03495 1efb66053ace5af99f8d2feda7658986 468 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 27 457 7.4E-91 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L04_03495 1efb66053ace5af99f8d2feda7658986 468 Pfam PF10559 Plug domain of Sec61p 38 71 1.9E-11 T 23-10-2018 IPR019561 Translocon Sec61/SecY, plug domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L04_03495 1efb66053ace5af99f8d2feda7658986 468 Hamap MF_01465 Protein translocase subunit SecY [secY]. 17 463 21.72 T 23-10-2018 IPR026593 Protein translocase subunit SecY A3L04_10410 e4b5ad997c008783d157535550c8c1a0 136 Pfam PF01886 Protein of unknown function DUF61 5 132 9.4E-37 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A3L04_10410 e4b5ad997c008783d157535550c8c1a0 136 ProDom PD016056 UPF0216 PYRAB16100 PH0358 MTH949 MK1676 AF0460 PF0452 MJ1224 23 134 5.0E-26 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A3L04_10410 e4b5ad997c008783d157535550c8c1a0 136 Hamap MF_00585 UPF0216 protein . 4 135 27.188 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A3L04_10410 e4b5ad997c008783d157535550c8c1a0 136 PIRSF PIRSF005264 1 136 2.3E-53 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A3L04_09145 cff10e423049777bb7e0e0448af3c41d 597 Pfam PF00009 Elongation factor Tu GTP binding domain 8 214 1.1E-32 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_09145 cff10e423049777bb7e0e0448af3c41d 597 Pfam PF03144 Elongation factor Tu domain 2 247 325 4.3E-13 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A3L04_09145 cff10e423049777bb7e0e0448af3c41d 597 SUPERFAMILY SSF50447 465 592 5.3E-28 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L04_09145 cff10e423049777bb7e0e0448af3c41d 597 PRINTS PR00315 GTP-binding elongation factor signature 8 21 1.8E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_09145 cff10e423049777bb7e0e0448af3c41d 597 PRINTS PR00315 GTP-binding elongation factor signature 74 84 1.8E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_09145 cff10e423049777bb7e0e0448af3c41d 597 PRINTS PR00315 GTP-binding elongation factor signature 90 101 1.8E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_09145 cff10e423049777bb7e0e0448af3c41d 597 PRINTS PR00315 GTP-binding elongation factor signature 126 135 1.8E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_09145 cff10e423049777bb7e0e0448af3c41d 597 Gene3D G3DSA:3.40.50.300 1 227 1.8E-64 T 23-10-2018 A3L04_09145 cff10e423049777bb7e0e0448af3c41d 597 SUPERFAMILY SSF52540 5 288 1.54E-54 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09145 cff10e423049777bb7e0e0448af3c41d 597 Gene3D G3DSA:3.40.50.10050 349 457 5.0E-36 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily A3L04_09145 cff10e423049777bb7e0e0448af3c41d 597 TIGRFAM TIGR00491 aIF-2: translation initiation factor aIF-2 3 594 1.6E-245 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 A3L04_09145 cff10e423049777bb7e0e0448af3c41d 597 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 150 2.4E-20 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L04_09145 cff10e423049777bb7e0e0448af3c41d 597 SUPERFAMILY SSF52156 334 460 2.48E-35 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily A3L04_09145 cff10e423049777bb7e0e0448af3c41d 597 Pfam PF11987 Translation-initiation factor 2 348 446 2.2E-23 T 23-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 A3L04_09145 cff10e423049777bb7e0e0448af3c41d 597 Gene3D G3DSA:2.40.30.10 466 556 2.3E-30 T 23-10-2018 A3L04_09145 cff10e423049777bb7e0e0448af3c41d 597 Gene3D G3DSA:2.40.30.10 228 338 2.1E-40 T 23-10-2018 A3L04_09145 cff10e423049777bb7e0e0448af3c41d 597 Pfam PF14578 Elongation factor Tu domain 4 467 553 3.9E-30 T 23-10-2018 IPR029459 Elongation factor Tu-type domain A3L04_09145 cff10e423049777bb7e0e0448af3c41d 597 Hamap MF_00100_A Translation initiation factor IF-2 [infB]. 2 596 43.802 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 A3L04_06060 4c465d59a714c36e474728e4db821358 211 PIRSF PIRSF000887 3 203 7.6E-42 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 A3L04_06060 4c465d59a714c36e474728e4db821358 211 SUPERFAMILY SSF56300 16 152 3.8E-21 T 23-10-2018 A3L04_06060 4c465d59a714c36e474728e4db821358 211 Pfam PF00149 Calcineurin-like phosphoesterase 16 129 3.0E-11 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L04_06060 4c465d59a714c36e474728e4db821358 211 Gene3D G3DSA:3.60.21.10 16 120 1.8E-12 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L04_01310 d1b4abeeeb3c118faa974b7d3bf9d35e 488 SUPERFAMILY SSF64182 162 453 2.62E-57 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L04_01310 d1b4abeeeb3c118faa974b7d3bf9d35e 488 Gene3D G3DSA:3.90.1640.10 161 350 8.4E-26 T 23-10-2018 A3L04_01310 d1b4abeeeb3c118faa974b7d3bf9d35e 488 Gene3D G3DSA:3.40.50.720 1 140 1.5E-21 T 23-10-2018 A3L04_01310 d1b4abeeeb3c118faa974b7d3bf9d35e 488 Pfam PF02254 TrkA-N domain 3 126 3.6E-18 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A3L04_01310 d1b4abeeeb3c118faa974b7d3bf9d35e 488 Pfam PF02272 DHHA1 domain 355 473 6.1E-17 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L04_01310 d1b4abeeeb3c118faa974b7d3bf9d35e 488 Pfam PF01368 DHH family 165 315 1.2E-10 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A3L04_01310 d1b4abeeeb3c118faa974b7d3bf9d35e 488 SUPERFAMILY SSF51735 1 138 1.22E-19 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_07685 42f5f20e13acca5eedd81530a5f1665b 385 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 43 100 5.7E-8 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A3L04_07685 42f5f20e13acca5eedd81530a5f1665b 385 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 153 368 1.2E-33 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L04_07685 42f5f20e13acca5eedd81530a5f1665b 385 SUPERFAMILY SSF161098 130 349 1.14E-29 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_07685 42f5f20e13acca5eedd81530a5f1665b 385 Gene3D G3DSA:1.10.3720.10 124 367 3.5E-27 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_00750 fb6b2ac81b13e42ca952073e79b9e091 93 SUPERFAMILY SSF88723 2 91 1.23E-14 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_00750 fb6b2ac81b13e42ca952073e79b9e091 93 Gene3D G3DSA:3.40.50.1010 1 88 1.2E-13 T 23-10-2018 A3L04_00750 fb6b2ac81b13e42ca952073e79b9e091 93 Pfam PF01850 PIN domain 2 86 1.3E-11 T 23-10-2018 IPR002716 PIN domain A3L04_05585 1f2c5272ef505bf0d44b5dbe5829a161 227 Gene3D G3DSA:3.30.1360.40 2 84 1.4E-27 T 23-10-2018 A3L04_05585 1f2c5272ef505bf0d44b5dbe5829a161 227 Gene3D G3DSA:2.40.100.10 85 225 1.1E-61 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A3L04_05585 1f2c5272ef505bf0d44b5dbe5829a161 227 SUPERFAMILY SSF50891 86 216 1.21E-46 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A3L04_05585 1f2c5272ef505bf0d44b5dbe5829a161 227 SUPERFAMILY SSF160467 3 90 1.83E-23 T 23-10-2018 A3L04_05585 1f2c5272ef505bf0d44b5dbe5829a161 227 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 3 198 7.6E-74 T 23-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A3L04_05585 1f2c5272ef505bf0d44b5dbe5829a161 227 SMART SM00796 2 200 8.6E-108 T 23-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A3L04_05585 1f2c5272ef505bf0d44b5dbe5829a161 227 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 7 209 6.7E-67 T 23-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A3L04_07950 908155bfc3594af1b3ac5d97cc2150e8 443 Pfam PF00202 Aminotransferase class-III 20 424 6.4E-116 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L04_07950 908155bfc3594af1b3ac5d97cc2150e8 443 Gene3D G3DSA:3.90.1150.10 6 420 1.1E-149 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L04_07950 908155bfc3594af1b3ac5d97cc2150e8 443 SUPERFAMILY SSF53383 13 426 1.16E-128 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L04_07950 908155bfc3594af1b3ac5d97cc2150e8 443 PIRSF PIRSF000521 122 427 6.1E-37 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L04_07950 908155bfc3594af1b3ac5d97cc2150e8 443 PIRSF PIRSF000521 18 129 2.7E-7 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L04_07950 908155bfc3594af1b3ac5d97cc2150e8 443 Gene3D G3DSA:3.40.640.10 59 324 1.1E-149 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L04_07950 908155bfc3594af1b3ac5d97cc2150e8 443 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 241 278 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L04_05235 106dbed11932885c0fe2eb0386a8db11 405 Gene3D G3DSA:3.20.20.80 86 404 6.0E-6 T 23-10-2018 A3L04_05235 106dbed11932885c0fe2eb0386a8db11 405 SUPERFAMILY SSF51445 87 182 2.57E-5 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L04_05235 106dbed11932885c0fe2eb0386a8db11 405 SUPERFAMILY SSF51445 270 394 9.09E-6 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L04_08675 9bfafaa9f567ba7ff4b77cdb93d9d26b 158 Gene3D G3DSA:2.70.70.10 6 138 8.3E-30 T 23-10-2018 IPR011055 Duplicated hybrid motif A3L04_08675 9bfafaa9f567ba7ff4b77cdb93d9d26b 158 SUPERFAMILY SSF51261 17 115 9.42E-26 T 23-10-2018 IPR011055 Duplicated hybrid motif A3L04_08675 9bfafaa9f567ba7ff4b77cdb93d9d26b 158 Pfam PF01551 Peptidase family M23 20 116 1.9E-20 T 23-10-2018 IPR016047 Peptidase M23 A3L04_00680 be61e611118e9a870a77a987a08b416b 198 SUPERFAMILY SSF50249 67 188 4.29E-28 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_00680 be61e611118e9a870a77a987a08b416b 198 Hamap MF_00975 Exosome complex component Csl4 [csl4]. 15 195 27.882 T 23-10-2018 IPR030850 Exosome complex component Csl4, archaea GO:0000178|GO:0006396 A3L04_00680 be61e611118e9a870a77a987a08b416b 198 Gene3D G3DSA:2.20.70.10 158 191 3.5E-17 T 23-10-2018 A3L04_00680 be61e611118e9a870a77a987a08b416b 198 Pfam PF10447 Exosome component EXOSC1/CSL4 69 123 2.1E-4 T 23-10-2018 IPR019495 Exosome complex component CSL4, C-terminal GO:0000178|GO:0003723 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L04_00680 be61e611118e9a870a77a987a08b416b 198 Gene3D G3DSA:2.40.50.140 68 157 7.7E-23 T 23-10-2018 A3L04_00680 be61e611118e9a870a77a987a08b416b 198 SMART SM00316 71 151 3.6E-7 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L04_00680 be61e611118e9a870a77a987a08b416b 198 Gene3D G3DSA:2.40.50.100 14 63 1.2E-15 T 23-10-2018 A3L04_00680 be61e611118e9a870a77a987a08b416b 198 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 15 51 2.1E-9 T 23-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L04_00680 be61e611118e9a870a77a987a08b416b 198 SUPERFAMILY SSF110324 14 66 2.51E-12 T 23-10-2018 A3L04_03030 bd203eec9dbbb356222ecf32270d302a 318 Pfam PF13732 Domain of unknown function (DUF4162) 234 312 9.8E-7 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 A3L04_03030 bd203eec9dbbb356222ecf32270d302a 318 SUPERFAMILY SSF52540 3 235 3.55E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_03030 bd203eec9dbbb356222ecf32270d302a 318 SMART SM00382 39 232 9.2E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_03030 bd203eec9dbbb356222ecf32270d302a 318 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 26 313 9.8E-103 T 23-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A3L04_03030 bd203eec9dbbb356222ecf32270d302a 318 Pfam PF00005 ABC transporter 30 174 8.5E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_03030 bd203eec9dbbb356222ecf32270d302a 318 Gene3D G3DSA:3.40.50.300 1 250 8.8E-69 T 23-10-2018 A3L04_08995 9375c758f2c462bfac4d210cbec00bbe 339 Pfam PF12225 Methylene-tetrahydrofolate reductase C terminal 3 42 2.4E-9 T 23-10-2018 IPR022026 Methylene-tetrahydrofolate reductase C-terminal A3L04_08995 9375c758f2c462bfac4d210cbec00bbe 339 SUPERFAMILY SSF51730 102 306 5.69E-27 T 23-10-2018 IPR029041 FAD-linked oxidoreductase-like A3L04_08995 9375c758f2c462bfac4d210cbec00bbe 339 Pfam PF02219 Methylenetetrahydrofolate reductase 116 255 4.0E-7 T 23-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 A3L04_08995 9375c758f2c462bfac4d210cbec00bbe 339 Gene3D G3DSA:3.20.20.220 85 318 2.0E-15 T 23-10-2018 A3L04_06730 cda40d6089d5469d48cd4fe968572a89 142 Gene3D G3DSA:3.40.50.720 4 142 1.1E-49 T 23-10-2018 A3L04_06730 cda40d6089d5469d48cd4fe968572a89 142 SMART SM00881 18 111 1.0E-28 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L04_06730 cda40d6089d5469d48cd4fe968572a89 142 Pfam PF13380 CoA binding domain 23 137 7.1E-40 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L04_06730 cda40d6089d5469d48cd4fe968572a89 142 SUPERFAMILY SSF51735 7 139 5.07E-45 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_09560 b7c21c51d1e41216a6346118580c5832 172 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 159 1.6E-72 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A3L04_09560 b7c21c51d1e41216a6346118580c5832 172 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 156 35.256 T 23-10-2018 IPR033747 Class I PurE A3L04_09560 b7c21c51d1e41216a6346118580c5832 172 SMART SM01001 3 152 1.3E-109 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A3L04_09560 b7c21c51d1e41216a6346118580c5832 172 Pfam PF00731 AIR carboxylase 4 150 2.7E-73 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A3L04_09560 b7c21c51d1e41216a6346118580c5832 172 SUPERFAMILY SSF52255 3 169 1.31E-72 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 A3L04_09560 b7c21c51d1e41216a6346118580c5832 172 Gene3D G3DSA:3.40.50.7700 1 172 5.9E-85 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 A3L04_09560 b7c21c51d1e41216a6346118580c5832 172 PIRSF PIRSF001338 1 163 1.9E-77 T 23-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 A3L04_04840 ec9e722326588a42fe2b243f7ed24179 449 Pfam PF01637 ATPase domain predominantly from Archaea 5 200 2.8E-26 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_04840 ec9e722326588a42fe2b243f7ed24179 449 SUPERFAMILY SSF52540 3 238 7.19E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_04840 ec9e722326588a42fe2b243f7ed24179 449 Gene3D G3DSA:3.40.50.300 2 165 1.4E-31 T 23-10-2018 A3L04_04840 ec9e722326588a42fe2b243f7ed24179 449 Pfam PF01022 Bacterial regulatory protein, arsR family 240 279 8.5E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_04840 ec9e722326588a42fe2b243f7ed24179 449 Pfam PF03008 Archaea bacterial proteins of unknown function 306 398 1.5E-26 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L04_04840 ec9e722326588a42fe2b243f7ed24179 449 SUPERFAMILY SSF46785 239 312 8.88E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_06665 76cf11b61f37da6b90820b1d725ee45c 601 SMART SM00670 2 115 9.6E-26 T 23-10-2018 IPR002716 PIN domain A3L04_06665 76cf11b61f37da6b90820b1d725ee45c 601 Pfam PF00437 Type II/IV secretion system protein 213 370 8.3E-10 T 23-10-2018 IPR001482 Type II/IV secretion system protein A3L04_06665 76cf11b61f37da6b90820b1d725ee45c 601 Gene3D G3DSA:3.40.50.300 236 405 1.9E-18 T 23-10-2018 A3L04_06665 76cf11b61f37da6b90820b1d725ee45c 601 SMART SM00382 257 392 3.1E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_06665 76cf11b61f37da6b90820b1d725ee45c 601 Gene3D G3DSA:3.30.310.210 434 546 2.9E-5 T 23-10-2018 A3L04_06665 76cf11b61f37da6b90820b1d725ee45c 601 SUPERFAMILY SSF54814 468 520 1.96E-6 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L04_06665 76cf11b61f37da6b90820b1d725ee45c 601 SUPERFAMILY SSF52540 136 440 2.63E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_06665 76cf11b61f37da6b90820b1d725ee45c 601 Pfam PF00013 KH domain 493 524 1.3E-4 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A3L04_06665 76cf11b61f37da6b90820b1d725ee45c 601 SUPERFAMILY SSF88723 3 131 6.45E-17 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_06665 76cf11b61f37da6b90820b1d725ee45c 601 Gene3D G3DSA:3.40.50.1010 1 127 8.6E-35 T 23-10-2018 A3L04_07105 47834244621376718d9a944ac639c787 196 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 3 194 36.322 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L04_07105 47834244621376718d9a944ac639c787 196 PIRSF PIRSF005639 1 196 1.7E-71 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L04_07105 47834244621376718d9a944ac639c787 196 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 2 193 1.7E-79 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L04_07105 47834244621376718d9a944ac639c787 196 Pfam PF01174 SNO glutamine amidotransferase family 5 194 6.4E-60 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L04_07105 47834244621376718d9a944ac639c787 196 ProSitePatterns PS01236 PdxT/SNO family family signature. 46 56 - T 23-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L04_07105 47834244621376718d9a944ac639c787 196 Gene3D G3DSA:3.40.50.880 1 196 1.5E-71 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L04_07105 47834244621376718d9a944ac639c787 196 SUPERFAMILY SSF52317 2 193 1.15E-51 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L04_08765 4910b3af2fbb2e4f4eda71c4a09213e6 252 SUPERFAMILY SSF51556 2 250 3.52E-57 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L04_08765 4910b3af2fbb2e4f4eda71c4a09213e6 252 PIRSF PIRSF005902 1 251 2.0E-59 T 23-10-2018 IPR001130 TatD family GO:0016788 A3L04_08765 4910b3af2fbb2e4f4eda71c4a09213e6 252 Pfam PF01026 TatD related DNase 2 248 5.1E-59 T 23-10-2018 IPR001130 TatD family GO:0016788 A3L04_08765 4910b3af2fbb2e4f4eda71c4a09213e6 252 Gene3D G3DSA:3.20.20.140 1 251 2.2E-66 T 23-10-2018 A3L04_08765 4910b3af2fbb2e4f4eda71c4a09213e6 252 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 1 249 3.9E-72 T 23-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 A3L04_02050 1de1d875418d807090f89c0aad1ffdd9 404 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 189 232 1.5E-13 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L04_02050 1de1d875418d807090f89c0aad1ffdd9 404 Pfam PF01411 tRNA synthetases class II (A) 24 95 3.0E-13 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A3L04_02050 1de1d875418d807090f89c0aad1ffdd9 404 Gene3D G3DSA:2.40.30.130 1 91 4.0E-21 T 23-10-2018 A3L04_02050 1de1d875418d807090f89c0aad1ffdd9 404 SUPERFAMILY SSF50447 1 90 5.3E-18 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L04_02050 1de1d875418d807090f89c0aad1ffdd9 404 SUPERFAMILY SSF55186 93 236 1.44E-35 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A3L04_02050 1de1d875418d807090f89c0aad1ffdd9 404 Gene3D G3DSA:3.30.980.10 93 247 1.2E-42 T 23-10-2018 A3L04_02050 1de1d875418d807090f89c0aad1ffdd9 404 Pfam PF02272 DHHA1 domain 268 402 2.4E-16 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L04_02050 1de1d875418d807090f89c0aad1ffdd9 404 SMART SM00863 189 232 1.1E-15 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L04_02050 1de1d875418d807090f89c0aad1ffdd9 404 Gene3D G3DSA:3.10.310.40 300 403 1.1E-7 T 23-10-2018 A3L04_08580 de13f3271b3c5a3bf6e18faa9b07d6b1 278 PIRSF PIRSF006816 1 255 2.5E-71 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L04_08580 de13f3271b3c5a3bf6e18faa9b07d6b1 278 SUPERFAMILY SSF52343 88 248 1.11E-31 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L04_08580 de13f3271b3c5a3bf6e18faa9b07d6b1 278 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 213 249 9.8E-13 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L04_08580 de13f3271b3c5a3bf6e18faa9b07d6b1 278 Gene3D G3DSA:3.40.50.80 99 203 4.0E-41 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L04_08580 de13f3271b3c5a3bf6e18faa9b07d6b1 278 SUPERFAMILY SSF63380 2 91 3.63E-20 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L04_08580 de13f3271b3c5a3bf6e18faa9b07d6b1 278 Gene3D G3DSA:2.40.30.10 1 91 6.4E-22 T 23-10-2018 A3L04_09035 7c44acf151f892ba39fd828382b156f1 209 TIGRFAM TIGR01895 cas_Cas5t: CRISPR-associated protein Cas5, subtype I-B/TNEAP 1 199 5.3E-57 T 23-10-2018 IPR013337 CRISPR-associated protein Cas5, Tneap type A3L04_09035 7c44acf151f892ba39fd828382b156f1 209 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 1 43 1.8E-13 T 23-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal A3L04_08010 2fca89bc6cb344b8649899ea4868bb45 164 Pfam PF13247 4Fe-4S dicluster domain 41 133 1.3E-27 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L04_08010 2fca89bc6cb344b8649899ea4868bb45 164 SUPERFAMILY SSF54862 3 138 7.12E-53 T 23-10-2018 A3L04_08010 2fca89bc6cb344b8649899ea4868bb45 164 Gene3D G3DSA:3.30.70.20 26 161 3.9E-41 T 23-10-2018 A3L04_08010 2fca89bc6cb344b8649899ea4868bb45 164 Pfam PF12800 4Fe-4S binding domain 10 24 0.0031 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L04_08010 2fca89bc6cb344b8649899ea4868bb45 164 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 78 89 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_02370 ebe4fb51c1bdfdcc6d5443a5b2f57f6b 61 SMART SM01389 3 61 1.9E-29 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A3L04_02370 ebe4fb51c1bdfdcc6d5443a5b2f57f6b 61 ProDom PD019197 RNA DNA-DIRECTED POLYMERASE SUBUNIT E'' POLYMERASE RPOE2 TRANSFERASE NUCLEOTIDYLTRANSFERASE E 18 60 6.0E-18 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 A3L04_02370 ebe4fb51c1bdfdcc6d5443a5b2f57f6b 61 Gene3D G3DSA:2.20.28.90 1 61 1.1E-32 T 23-10-2018 IPR038589 Archaeal transcription elongation factor Spt4 superfamily A3L04_02370 ebe4fb51c1bdfdcc6d5443a5b2f57f6b 61 Pfam PF06093 Spt4/RpoE2 zinc finger 3 61 7.0E-17 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A3L04_02370 ebe4fb51c1bdfdcc6d5443a5b2f57f6b 61 SUPERFAMILY SSF63393 3 61 4.71E-22 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A3L04_02370 ebe4fb51c1bdfdcc6d5443a5b2f57f6b 61 Hamap MF_00949 Transcription elongation factor Spt4 [spt4]. 5 61 29.16 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 A3L04_03135 b4e20a16b3b1090cb77479a4af4693ca 276 Pfam PF00589 Phage integrase family 95 257 1.6E-51 T 23-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A3L04_03135 b4e20a16b3b1090cb77479a4af4693ca 276 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 4 73 6.7E-6 T 23-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A3L04_03135 b4e20a16b3b1090cb77479a4af4693ca 276 Gene3D G3DSA:1.10.443.10 87 275 2.9E-82 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A3L04_03135 b4e20a16b3b1090cb77479a4af4693ca 276 Gene3D G3DSA:1.10.150.130 2 86 2.9E-23 T 23-10-2018 IPR010998 Integrase/recombinase, N-terminal A3L04_03135 b4e20a16b3b1090cb77479a4af4693ca 276 SUPERFAMILY SSF56349 5 265 2.62E-62 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A3L04_03135 b4e20a16b3b1090cb77479a4af4693ca 276 Hamap MF_02055 Tyrosine recombinase XerA [xerA]. 1 268 43.697 T 23-10-2018 IPR033686 Tyrosine recombinase XerA A3L04_04710 17c19f91f1de9c206c1ec5b02a62b724 415 Pfam PF04409 Protein of unknown function (DUF530) 32 257 8.0E-15 T 23-10-2018 IPR007503 Protein of unknown function DUF530 A3L04_04710 17c19f91f1de9c206c1ec5b02a62b724 415 PIRSF PIRSF018863 1 415 9.1E-247 T 23-10-2018 IPR014496 Uncharacterised conserved protein UCP018863 A3L04_09685 290e551779f9633ad265f23ef98637b1 187 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 88 106 6.7E-8 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_09685 290e551779f9633ad265f23ef98637b1 187 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 6.7E-8 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_09685 290e551779f9633ad265f23ef98637b1 187 Gene3D G3DSA:3.40.50.300 1 181 2.9E-38 T 23-10-2018 A3L04_09685 290e551779f9633ad265f23ef98637b1 187 Pfam PF01926 50S ribosome-binding GTPase 3 136 6.6E-23 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_09685 290e551779f9633ad265f23ef98637b1 187 SUPERFAMILY SSF52540 2 182 1.09E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09685 290e551779f9633ad265f23ef98637b1 187 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 176 2.0E-21 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L04_06380 13d60ab44cb1be79b6ff54257603ac38 299 Pfam PF13643 Domain of unknown function (DUF4145) 196 286 3.4E-22 T 23-10-2018 IPR025285 Domain of unknown function DUF4145 A3L04_02110 4f845fd5db2376bce5d1b8776cc9cac9 80 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 5 76 4.1E-24 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L04_02110 4f845fd5db2376bce5d1b8776cc9cac9 80 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 3 76 19.579 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L04_02110 4f845fd5db2376bce5d1b8776cc9cac9 80 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 77 2.6E-23 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L04_02110 4f845fd5db2376bce5d1b8776cc9cac9 80 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 12 77 8.0E-22 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L04_02110 4f845fd5db2376bce5d1b8776cc9cac9 80 Gene3D G3DSA:3.30.1280.10 1 80 7.2E-27 T 23-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L04_02110 4f845fd5db2376bce5d1b8776cc9cac9 80 SUPERFAMILY SSF82697 3 78 1.62E-23 T 23-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L04_04290 781d32becabad8028259cb2ce2774f18 222 Hamap MF_00052_A Ribonuclease HII [rnhB]. 2 206 37.82 T 23-10-2018 IPR020787 Ribonuclease HII, archaea GO:0004523|GO:0005737|GO:0006401|GO:0030145 A3L04_04290 781d32becabad8028259cb2ce2774f18 222 TIGRFAM TIGR00729 TIGR00729: ribonuclease HII 3 205 9.7E-82 T 23-10-2018 IPR004649 Ribonuclease H2, subunit A GO:0004523|GO:0016070 A3L04_04290 781d32becabad8028259cb2ce2774f18 222 SUPERFAMILY SSF53098 1 209 2.73E-59 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily A3L04_04290 781d32becabad8028259cb2ce2774f18 222 Gene3D G3DSA:1.10.10.460 162 208 6.3E-24 T 23-10-2018 IPR023160 Ribonuclease HII, helix-loop-helix cap domain superfamily GO:0004523 A3L04_04290 781d32becabad8028259cb2ce2774f18 222 Gene3D G3DSA:3.30.420.10 2 161 2.9E-56 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A3L04_04290 781d32becabad8028259cb2ce2774f18 222 Pfam PF01351 Ribonuclease HII 4 201 5.0E-52 T 23-10-2018 IPR024567 Ribonuclease HII/HIII domain A3L04_04940 43055885e78bfa3e187ebad27020fe5e 241 SUPERFAMILY SSF52540 4 226 8.64E-62 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_04940 43055885e78bfa3e187ebad27020fe5e 241 Pfam PF00005 ABC transporter 19 163 3.2E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_04940 43055885e78bfa3e187ebad27020fe5e 241 Gene3D G3DSA:3.40.50.300 1 241 5.1E-71 T 23-10-2018 A3L04_04940 43055885e78bfa3e187ebad27020fe5e 241 SMART SM00382 28 219 1.1E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_06165 351f38969d396e33ae24373cb04e6949 133 SUPERFAMILY SSF111038 3 130 1.57E-45 T 23-10-2018 IPR035917 YjbQ-like superfamily A3L04_06165 351f38969d396e33ae24373cb04e6949 133 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 95 113 - T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L04_06165 351f38969d396e33ae24373cb04e6949 133 Gene3D G3DSA:2.60.120.460 1 132 1.7E-53 T 23-10-2018 IPR035917 YjbQ-like superfamily A3L04_06165 351f38969d396e33ae24373cb04e6949 133 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 5 130 3.0E-47 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L04_06165 351f38969d396e33ae24373cb04e6949 133 PIRSF PIRSF004681 1 132 9.6E-43 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L04_06165 351f38969d396e33ae24373cb04e6949 133 Pfam PF01894 Uncharacterised protein family UPF0047 17 130 3.5E-42 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L04_09475 b13781aa6556282b7e645a3f71dd4182 172 SMART SM00359 88 163 2.8E-26 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L04_09475 b13781aa6556282b7e645a3f71dd4182 172 Pfam PF01472 PUA domain 89 161 4.5E-26 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L04_09475 b13781aa6556282b7e645a3f71dd4182 172 Gene3D G3DSA:3.10.450.120 1 78 2.0E-36 T 23-10-2018 A3L04_09475 b13781aa6556282b7e645a3f71dd4182 172 TIGRFAM TIGR03684 arCOG00985: arCOG04150 universal archaeal PUA-domain protein 6 169 4.5E-56 T 23-10-2018 IPR022430 Conserved hypothetical protein CHP03684 A3L04_09475 b13781aa6556282b7e645a3f71dd4182 172 PIRSF PIRSF005067 1 172 2.5E-45 T 23-10-2018 IPR016437 MCT-1/Tma20 A3L04_09475 b13781aa6556282b7e645a3f71dd4182 172 SUPERFAMILY SSF88697 88 168 1.49E-24 T 23-10-2018 IPR015947 PUA-like superfamily A3L04_09475 b13781aa6556282b7e645a3f71dd4182 172 Gene3D G3DSA:2.30.130.10 79 172 2.0E-36 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L04_09475 b13781aa6556282b7e645a3f71dd4182 172 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 52 164 1.5E-32 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L04_09475 b13781aa6556282b7e645a3f71dd4182 172 Pfam PF09183 Domain of unknown function (DUF1947) 6 75 1.1E-5 T 23-10-2018 IPR015266 Domain of unknown function DUF1947 A3L04_00045 c39a470908cfcf457f317fa14d20730e 589 Pfam PF16199 Radical_SAM C-terminal domain 333 412 8.5E-26 T 23-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 A3L04_00045 c39a470908cfcf457f317fa14d20730e 589 TIGRFAM TIGR01211 ELP3: radical SAM enzyme/protein acetyltransferase, ELP3 family 10 570 3.6E-268 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 A3L04_00045 c39a470908cfcf457f317fa14d20730e 589 SUPERFAMILY SSF102114 82 379 2.35E-33 T 23-10-2018 A3L04_00045 c39a470908cfcf457f317fa14d20730e 589 PIRSF PIRSF005669 1 571 5.4E-251 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 A3L04_00045 c39a470908cfcf457f317fa14d20730e 589 Gene3D G3DSA:3.80.30.20 231 379 3.1E-12 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L04_00045 c39a470908cfcf457f317fa14d20730e 589 SMART SM00729 77 372 3.5E-47 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L04_00045 c39a470908cfcf457f317fa14d20730e 589 SUPERFAMILY SSF55729 448 566 1.78E-10 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L04_00045 c39a470908cfcf457f317fa14d20730e 589 Pfam PF00583 Acetyltransferase (GNAT) family 458 559 1.8E-8 T 23-10-2018 IPR000182 GNAT domain A3L04_00045 c39a470908cfcf457f317fa14d20730e 589 Gene3D G3DSA:3.40.630.30 411 571 2.6E-9 T 23-10-2018 A3L04_00045 c39a470908cfcf457f317fa14d20730e 589 Pfam PF04055 Radical SAM superfamily 84 316 2.1E-29 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_07965 6cd385d195de91ff86e5cf51023d2b30 296 SUPERFAMILY SSF54862 56 121 1.73E-17 T 23-10-2018 A3L04_07965 6cd385d195de91ff86e5cf51023d2b30 296 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 71 82 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_07965 6cd385d195de91ff86e5cf51023d2b30 296 SUPERFAMILY SSF52540 2 294 1.33E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_07965 6cd385d195de91ff86e5cf51023d2b30 296 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 101 112 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_07965 6cd385d195de91ff86e5cf51023d2b30 296 Pfam PF14697 4Fe-4S dicluster domain 64 118 4.9E-12 T 23-10-2018 A3L04_07965 6cd385d195de91ff86e5cf51023d2b30 296 Gene3D G3DSA:3.30.70.20 69 116 5.7E-10 T 23-10-2018 A3L04_07965 6cd385d195de91ff86e5cf51023d2b30 296 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 265 1.1E-22 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L04_07740 155fa969f61c6894fc5481bad20a55b6 617 Pfam PF05123 S-layer like family, N-terminal region 4 328 1.8E-61 T 23-10-2018 IPR022650 S-layer protein, N-terminal A3L04_07740 155fa969f61c6894fc5481bad20a55b6 617 Pfam PF05124 S-layer like family, C-terminal region 377 613 1.7E-54 T 23-10-2018 IPR022651 S-layer protein, C-terminal A3L04_07740 155fa969f61c6894fc5481bad20a55b6 617 TIGRFAM TIGR01564 S_layer_MJ: S-layer protein 4 613 1.1E-142 T 23-10-2018 IPR006454 S-layer protein GO:0005618 A3L04_03420 18668a2570e0a782792b2e213aef30fb 98 SMART SM00538 9 98 2.0E-40 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 A3L04_03420 18668a2570e0a782792b2e213aef30fb 98 SUPERFAMILY SSF101744 11 97 4.71E-29 T 23-10-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 A3L04_03420 18668a2570e0a782792b2e213aef30fb 98 Pfam PF01868 Domain of unknown function UPF0086 14 94 1.1E-23 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 A3L04_03420 18668a2570e0a782792b2e213aef30fb 98 Gene3D G3DSA:2.30.30.210 1 98 4.5E-43 T 23-10-2018 IPR036980 Ribonuclease P/MRP, subunit p29 superfamily GO:0003723|GO:0004540|GO:0008033|GO:0030677 Reactome: R-HSA-6784531 A3L04_03420 18668a2570e0a782792b2e213aef30fb 98 Hamap MF_00754 Ribonuclease P protein component 1 [rnp1]. 17 93 21.271 T 23-10-2018 IPR023538 Ribonuclease P protein component 1 GO:0001682|GO:0004526 A3L04_10420 30c5b9a6094a336743b7acb64bf07d75 370 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 3 278 2.8E-50 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 A3L04_10420 30c5b9a6094a336743b7acb64bf07d75 370 Pfam PF01494 FAD binding domain 3 162 3.6E-14 T 23-10-2018 IPR002938 FAD-binding domain GO:0071949 A3L04_10420 30c5b9a6094a336743b7acb64bf07d75 370 Gene3D G3DSA:3.50.50.60 1 368 1.7E-55 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_10420 30c5b9a6094a336743b7acb64bf07d75 370 SUPERFAMILY SSF51905 1 281 1.35E-31 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_10420 30c5b9a6094a336743b7acb64bf07d75 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 6.8E-11 T 23-10-2018 A3L04_10420 30c5b9a6094a336743b7acb64bf07d75 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 244 259 6.8E-11 T 23-10-2018 A3L04_10420 30c5b9a6094a336743b7acb64bf07d75 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 134 149 6.8E-11 T 23-10-2018 A3L04_05590 59269661da45ebe89a60a51ad2b97029 88 Gene3D G3DSA:3.40.50.1010 15 85 2.1E-17 T 23-10-2018 A3L04_05590 59269661da45ebe89a60a51ad2b97029 88 Pfam PF01850 PIN domain 20 78 5.3E-10 T 23-10-2018 IPR002716 PIN domain A3L04_05590 59269661da45ebe89a60a51ad2b97029 88 SUPERFAMILY SSF88723 1 85 2.16E-21 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_09620 e9f63a59b6d1a9f60c4bff51f7469f9e 387 SUPERFAMILY SSF50998 117 351 4.32E-17 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A3L04_09620 e9f63a59b6d1a9f60c4bff51f7469f9e 387 Pfam PF13360 PQQ-like domain 168 356 1.5E-9 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A3L04_09620 e9f63a59b6d1a9f60c4bff51f7469f9e 387 Gene3D G3DSA:2.130.10.10 10 364 7.6E-19 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A3L04_09620 e9f63a59b6d1a9f60c4bff51f7469f9e 387 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 368 387 2.9E-4 T 23-10-2018 IPR027552 CGP-CTERM domain A3L04_09620 e9f63a59b6d1a9f60c4bff51f7469f9e 387 SMART SM00564 252 282 200.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A3L04_09620 e9f63a59b6d1a9f60c4bff51f7469f9e 387 SMART SM00564 289 332 2.5 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A3L04_09620 e9f63a59b6d1a9f60c4bff51f7469f9e 387 SMART SM00564 164 204 0.086 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A3L04_09620 e9f63a59b6d1a9f60c4bff51f7469f9e 387 SMART SM00564 212 245 520.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A3L04_07945 911313a847daa789e5f05d7852045003 148 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 49 9.4E-19 T 23-10-2018 A3L04_07945 911313a847daa789e5f05d7852045003 148 SUPERFAMILY SSF54909 62 139 3.04E-17 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L04_07945 911313a847daa789e5f05d7852045003 148 Gene3D G3DSA:1.10.10.10 1 53 6.2E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_07945 911313a847daa789e5f05d7852045003 148 Gene3D G3DSA:3.30.70.920 54 143 1.7E-21 T 23-10-2018 A3L04_07945 911313a847daa789e5f05d7852045003 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 7.8E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_07945 911313a847daa789e5f05d7852045003 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 7.8E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_07945 911313a847daa789e5f05d7852045003 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 7.8E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_07945 911313a847daa789e5f05d7852045003 148 Pfam PF01037 Lrp/AsnC ligand binding domain 68 137 3.3E-15 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L04_07945 911313a847daa789e5f05d7852045003 148 SMART SM00344 2 108 2.3E-46 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L04_07945 911313a847daa789e5f05d7852045003 148 SUPERFAMILY SSF46785 2 70 1.65E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_04690 1035a37db40eea5f57b3eeb2d7eb3594 266 SMART SM00090 21 255 3.9E-120 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A3L04_04690 1035a37db40eea5f57b3eeb2d7eb3594 266 Gene3D G3DSA:3.30.200.20 50 149 2.8E-11 T 23-10-2018 A3L04_04690 1035a37db40eea5f57b3eeb2d7eb3594 266 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 189 200 - T 23-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A3L04_04690 1035a37db40eea5f57b3eeb2d7eb3594 266 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 189 201 - T 23-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 A3L04_04690 1035a37db40eea5f57b3eeb2d7eb3594 266 Gene3D G3DSA:1.10.510.10 154 265 5.6E-25 T 23-10-2018 A3L04_04690 1035a37db40eea5f57b3eeb2d7eb3594 266 Pfam PF01163 RIO1 family 63 245 7.9E-53 T 23-10-2018 A3L04_04690 1035a37db40eea5f57b3eeb2d7eb3594 266 SUPERFAMILY SSF56112 33 246 6.65E-23 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A3L04_00530 7fffe953bcf935c6c37f22b744850c57 613 Gene3D G3DSA:3.20.70.20 32 592 3.4E-72 T 23-10-2018 A3L04_00530 7fffe953bcf935c6c37f22b744850c57 613 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 21 610 1.3E-153 T 23-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 A3L04_00530 7fffe953bcf935c6c37f22b744850c57 613 SUPERFAMILY SSF51998 22 594 1.8E-130 T 23-10-2018 A3L04_00530 7fffe953bcf935c6c37f22b744850c57 613 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 21 609 9.3E-167 T 23-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 A3L04_01400 d49b8de71bc46e6a501facffc473c2fc 568 SUPERFAMILY SSF52141 265 418 1.31E-43 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L04_01400 d49b8de71bc46e6a501facffc473c2fc 568 Pfam PF01472 PUA domain 511 564 1.8E-12 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L04_01400 d49b8de71bc46e6a501facffc473c2fc 568 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 509 563 5.8E-10 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L04_01400 d49b8de71bc46e6a501facffc473c2fc 568 Gene3D G3DSA:2.30.130.10 500 568 2.9E-24 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L04_01400 d49b8de71bc46e6a501facffc473c2fc 568 SMART SM00359 500 567 4.6E-13 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L04_01400 d49b8de71bc46e6a501facffc473c2fc 568 SUPERFAMILY SSF88697 509 564 1.12E-13 T 23-10-2018 IPR015947 PUA-like superfamily A3L04_01400 d49b8de71bc46e6a501facffc473c2fc 568 SUPERFAMILY SSF88802 248 497 1.37E-14 T 23-10-2018 A3L04_01400 d49b8de71bc46e6a501facffc473c2fc 568 SUPERFAMILY SSF51713 1 242 4.45E-21 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L04_01400 d49b8de71bc46e6a501facffc473c2fc 568 Gene3D G3DSA:3.40.50.10630 250 420 3.5E-49 T 23-10-2018 A3L04_05380 29234e9c0e733e2be07e47e81443cb0c 135 Pfam PF01877 RNA binding 4 113 7.9E-15 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 A3L04_05380 29234e9c0e733e2be07e47e81443cb0c 135 Hamap MF_01112 UPF0201 protein . 3 132 24.655 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 A3L04_05380 29234e9c0e733e2be07e47e81443cb0c 135 SUPERFAMILY SSF55282 4 134 2.91E-38 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_05380 29234e9c0e733e2be07e47e81443cb0c 135 Gene3D G3DSA:3.30.1440.10 1 134 2.2E-44 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_05225 a597c4336bcd086e41b0b64e291bc8c8 320 SUPERFAMILY SSF55347 127 290 5.23E-19 T 23-10-2018 A3L04_05225 a597c4336bcd086e41b0b64e291bc8c8 320 SUPERFAMILY SSF51735 1 183 1.28E-40 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_05225 a597c4336bcd086e41b0b64e291bc8c8 320 Gene3D G3DSA:3.30.360.10 132 319 2.8E-32 T 23-10-2018 A3L04_05225 a597c4336bcd086e41b0b64e291bc8c8 320 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 114 7.8E-27 T 23-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A3L04_05225 a597c4336bcd086e41b0b64e291bc8c8 320 Gene3D G3DSA:3.40.50.720 1 131 8.7E-39 T 23-10-2018 A3L04_01040 315192de6bb7eff26a18fd13d6602321 327 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 12 259 5.5E-19 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR A3L04_01040 315192de6bb7eff26a18fd13d6602321 327 TIGRFAM TIGR02585 cas_Cst2_DevR: CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP 9 323 3.0E-88 T 23-10-2018 IPR013414 CRISPR-associated protein Cas7, subtype I-B/Tneap A3L04_01040 315192de6bb7eff26a18fd13d6602321 327 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 4 247 7.7E-61 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR A3L04_03900 f9ce7599582ee5c350b2c863ff93bb55 356 Hamap MF_00300 Chorismate synthase [aroC]. 6 353 35.894 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A3L04_03900 f9ce7599582ee5c350b2c863ff93bb55 356 PIRSF PIRSF001456 1 354 1.9E-141 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A3L04_03900 f9ce7599582ee5c350b2c863ff93bb55 356 Gene3D G3DSA:3.60.150.10 1 355 4.3E-137 T 23-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A3L04_03900 f9ce7599582ee5c350b2c863ff93bb55 356 ProSitePatterns PS00787 Chorismate synthase signature 1. 12 27 - T 23-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A3L04_03900 f9ce7599582ee5c350b2c863ff93bb55 356 Pfam PF01264 Chorismate synthase 7 346 3.4E-126 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A3L04_03900 f9ce7599582ee5c350b2c863ff93bb55 356 ProSitePatterns PS00788 Chorismate synthase signature 2. 120 136 - T 23-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A3L04_03900 f9ce7599582ee5c350b2c863ff93bb55 356 TIGRFAM TIGR00033 aroC: chorismate synthase 7 350 2.3E-121 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A3L04_03900 f9ce7599582ee5c350b2c863ff93bb55 356 ProSitePatterns PS00789 Chorismate synthase signature 3. 320 336 - T 23-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A3L04_03900 f9ce7599582ee5c350b2c863ff93bb55 356 SUPERFAMILY SSF103263 3 351 4.97E-126 T 23-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A3L04_07125 367b39865838b33cecfc6569551dcabc 332 Gene3D G3DSA:3.40.50.300 1 197 5.7E-19 T 23-10-2018 A3L04_07125 367b39865838b33cecfc6569551dcabc 332 ProDom PD003808 ATP-BINDING NUCLEOTIDE-BINDING PLASMID MJ0801 MJ0147 PYRAB06260 MJ0632 PYRAB09480 MJ0819 MJ1076 268 324 1.0E-12 T 23-10-2018 A3L04_07125 367b39865838b33cecfc6569551dcabc 332 Gene3D G3DSA:1.10.10.10 233 324 4.0E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_07125 367b39865838b33cecfc6569551dcabc 332 Pfam PF01637 ATPase domain predominantly from Archaea 2 236 1.7E-63 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_07125 367b39865838b33cecfc6569551dcabc 332 SUPERFAMILY SSF52540 1 249 8.54E-27 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_07125 367b39865838b33cecfc6569551dcabc 332 SMART SM00382 20 203 8.6E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_10255 c3573c50ff7f172b333fa04aaddebb7c 257 SUPERFAMILY SSF102522 1 161 9.81E-56 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal A3L04_10255 c3573c50ff7f172b333fa04aaddebb7c 257 Gene3D G3DSA:3.40.50.10790 1 160 5.7E-62 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal A3L04_10255 c3573c50ff7f172b333fa04aaddebb7c 257 SUPERFAMILY SSF101852 163 254 3.66E-25 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal A3L04_10255 c3573c50ff7f172b333fa04aaddebb7c 257 PIRSF PIRSF006779 1 256 1.0E-78 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase A3L04_10255 c3573c50ff7f172b333fa04aaddebb7c 257 Gene3D G3DSA:2.40.30.90 161 256 4.5E-35 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal A3L04_10255 c3573c50ff7f172b333fa04aaddebb7c 257 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 2 252 6.1E-79 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase A3L04_01155 9f59a0e34df28c39afc13d031402814d 580 SUPERFAMILY SSF102114 193 450 6.67E-23 T 23-10-2018 A3L04_01155 9f59a0e34df28c39afc13d031402814d 580 SMART SM00729 199 449 2.7E-33 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L04_01155 9f59a0e34df28c39afc13d031402814d 580 Gene3D G3DSA:3.80.30.20 199 456 1.2E-22 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L04_01155 9f59a0e34df28c39afc13d031402814d 580 SUPERFAMILY SSF81585 510 565 1.37E-7 T 23-10-2018 A3L04_01155 9f59a0e34df28c39afc13d031402814d 580 Pfam PF04055 Radical SAM superfamily 203 402 1.1E-24 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_03530 80b94187636fd3d267f6b267bc998144 186 Gene3D G3DSA:3.10.580.10 64 186 7.6E-28 T 23-10-2018 A3L04_03530 80b94187636fd3d267f6b267bc998144 186 SMART SM00530 12 66 4.6E-14 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L04_03530 80b94187636fd3d267f6b267bc998144 186 SUPERFAMILY SSF54631 67 184 8.46E-27 T 23-10-2018 A3L04_03530 80b94187636fd3d267f6b267bc998144 186 Gene3D G3DSA:1.10.260.40 10 63 1.3E-16 T 23-10-2018 A3L04_03530 80b94187636fd3d267f6b267bc998144 186 Pfam PF01381 Helix-turn-helix 13 60 1.6E-15 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L04_03530 80b94187636fd3d267f6b267bc998144 186 SMART SM00116 141 185 0.71 T 23-10-2018 IPR000644 CBS domain A3L04_03530 80b94187636fd3d267f6b267bc998144 186 SMART SM00116 77 124 8.2E-9 T 23-10-2018 IPR000644 CBS domain A3L04_03530 80b94187636fd3d267f6b267bc998144 186 PIRSF PIRSF037253 2 186 1.6E-79 T 23-10-2018 IPR017158 Transcription regulator, CBS domain-containing, predicted A3L04_03530 80b94187636fd3d267f6b267bc998144 186 SUPERFAMILY SSF47413 12 60 6.97E-14 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L04_03530 80b94187636fd3d267f6b267bc998144 186 Pfam PF00571 CBS domain 134 184 1.6E-7 T 23-10-2018 IPR000644 CBS domain A3L04_03530 80b94187636fd3d267f6b267bc998144 186 Pfam PF00571 CBS domain 70 123 9.6E-13 T 23-10-2018 IPR000644 CBS domain A3L04_07840 1406467f2887e1f8355af85b8007f770 142 Hamap MF_00498 UPF0179 protein . 1 139 24.146 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A3L04_07840 1406467f2887e1f8355af85b8007f770 142 Pfam PF03684 Uncharacterised protein family (UPF0179) 3 137 2.3E-43 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A3L04_07840 1406467f2887e1f8355af85b8007f770 142 ProDom PD016182 UPF0179 TK0790 TV1250 PAE0681 PF1381 AF2154 MA3685 VNG1401C MJ1627 PH1477 1 141 1.0E-66 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A3L04_07840 1406467f2887e1f8355af85b8007f770 142 PIRSF PIRSF006595 1 142 4.1E-51 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A3L04_05010 be07c6de2cee71d94f59d186d183f617 462 SMART SM00881 6 105 2.7E-39 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L04_05010 be07c6de2cee71d94f59d186d183f617 462 Gene3D G3DSA:3.40.50.261 297 462 2.5E-50 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L04_05010 be07c6de2cee71d94f59d186d183f617 462 SUPERFAMILY SSF52210 299 456 1.57E-34 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L04_05010 be07c6de2cee71d94f59d186d183f617 462 Gene3D G3DSA:3.40.50.261 135 296 4.4E-66 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L04_05010 be07c6de2cee71d94f59d186d183f617 462 SUPERFAMILY SSF52210 136 295 1.83E-46 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L04_05010 be07c6de2cee71d94f59d186d183f617 462 TIGRFAM TIGR02717 AcCoA-syn-alpha: acetyl coenzyme A synthetase (ADP forming), alpha domain 3 452 1.3E-190 T 23-10-2018 IPR014089 Acetate-CoA ligase [ADP-forming], alpha domain KEGG: 00010+6.2.1.13|KEGG: 00620+6.2.1.13|KEGG: 00640+6.2.1.13|MetaCyc: PWY-5483|MetaCyc: PWY-5535 A3L04_05010 be07c6de2cee71d94f59d186d183f617 462 Pfam PF13380 CoA binding domain 10 139 1.7E-21 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L04_05010 be07c6de2cee71d94f59d186d183f617 462 SUPERFAMILY SSF51735 3 134 1.28E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_05010 be07c6de2cee71d94f59d186d183f617 462 Gene3D G3DSA:3.40.50.720 1 134 1.3E-46 T 23-10-2018 A3L04_05010 be07c6de2cee71d94f59d186d183f617 462 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 156 293 2.3E-56 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L04_02830 31b6490474af44d93a24976684725455 145 Pfam PF01584 CheW-like domain 5 143 1.6E-37 T 23-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 A3L04_02830 31b6490474af44d93a24976684725455 145 Gene3D G3DSA:2.30.30.40 7 135 1.5E-42 T 23-10-2018 A3L04_02830 31b6490474af44d93a24976684725455 145 SUPERFAMILY SSF50341 3 143 1.57E-38 T 23-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 A3L04_02830 31b6490474af44d93a24976684725455 145 SMART SM00260 1 141 2.9E-50 T 23-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 A3L04_02830 31b6490474af44d93a24976684725455 145 Gene3D G3DSA:2.40.50.180 24 136 1.5E-42 T 23-10-2018 A3L04_04270 e399cc5ab20f132ba0dece7721218961 237 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 193 9.6E-35 T 23-10-2018 A3L04_04270 e399cc5ab20f132ba0dece7721218961 237 SUPERFAMILY SSF56784 1 225 2.89E-50 T 23-10-2018 IPR036412 HAD-like superfamily A3L04_04270 e399cc5ab20f132ba0dece7721218961 237 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 94 195 1.8E-14 T 23-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 A3L04_04270 e399cc5ab20f132ba0dece7721218961 237 Gene3D G3DSA:1.10.150.520 16 94 1.6E-91 T 23-10-2018 A3L04_04270 e399cc5ab20f132ba0dece7721218961 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 106 119 4.6E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_04270 e399cc5ab20f132ba0dece7721218961 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 175 4.6E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_04270 e399cc5ab20f132ba0dece7721218961 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 4.6E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_04270 e399cc5ab20f132ba0dece7721218961 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 137 153 4.6E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_04270 e399cc5ab20f132ba0dece7721218961 237 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 96 188 2.2E-14 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_04270 e399cc5ab20f132ba0dece7721218961 237 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 1 220 1.2E-92 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 A3L04_04270 e399cc5ab20f132ba0dece7721218961 237 Gene3D G3DSA:3.40.50.1000 4 220 1.6E-91 T 23-10-2018 IPR023214 HAD superfamily A3L04_04270 e399cc5ab20f132ba0dece7721218961 237 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 97 193 1.0E-10 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_03825 e488b9e0c1df4764f722967c506f31bc 217 Gene3D G3DSA:3.40.50.970 3 216 1.2E-64 T 23-10-2018 A3L04_03825 e488b9e0c1df4764f722967c506f31bc 217 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 41 214 2.2E-25 T 23-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A3L04_03825 e488b9e0c1df4764f722967c506f31bc 217 SUPERFAMILY SSF52518 38 214 2.18E-55 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L04_00495 1e47d39b245e5a98857dcb4dca2f6072 302 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 2 302 8.4E-113 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L04_00495 1e47d39b245e5a98857dcb4dca2f6072 302 Pfam PF02445 Quinolinate synthetase A protein 8 300 5.3E-112 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L04_00495 1e47d39b245e5a98857dcb4dca2f6072 302 Gene3D G3DSA:3.40.50.10800 8 282 7.4E-124 T 23-10-2018 A3L04_00495 1e47d39b245e5a98857dcb4dca2f6072 302 SUPERFAMILY SSF142754 5 301 1.57E-116 T 23-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L04_00495 1e47d39b245e5a98857dcb4dca2f6072 302 Gene3D G3DSA:3.40.50.10800 173 257 7.4E-124 T 23-10-2018 A3L04_00495 1e47d39b245e5a98857dcb4dca2f6072 302 Hamap MF_00568 Quinolinate synthase A [nadA]. 4 301 46.233 T 23-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L04_00495 1e47d39b245e5a98857dcb4dca2f6072 302 Gene3D G3DSA:3.40.50.10800 88 300 7.4E-124 T 23-10-2018 A3L04_00515 53ceba1fd4b462c64703f0cc6439e856 547 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 89 108 1.8E-36 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L04_00515 53ceba1fd4b462c64703f0cc6439e856 547 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 37 53 1.8E-36 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L04_00515 53ceba1fd4b462c64703f0cc6439e856 547 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 59 77 1.8E-36 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L04_00515 53ceba1fd4b462c64703f0cc6439e856 547 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 407 419 1.8E-36 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L04_00515 53ceba1fd4b462c64703f0cc6439e856 547 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 373 395 1.8E-36 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L04_00515 53ceba1fd4b462c64703f0cc6439e856 547 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 8 525 1.0E-247 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 A3L04_00515 53ceba1fd4b462c64703f0cc6439e856 547 Gene3D G3DSA:1.10.560.10 28 522 7.7E-220 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily A3L04_00515 53ceba1fd4b462c64703f0cc6439e856 547 Gene3D G3DSA:3.50.7.10 218 369 7.7E-220 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily A3L04_00515 53ceba1fd4b462c64703f0cc6439e856 547 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 40 52 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L04_00515 53ceba1fd4b462c64703f0cc6439e856 547 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 89 97 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L04_00515 53ceba1fd4b462c64703f0cc6439e856 547 SUPERFAMILY SSF48592 17 524 6.54E-97 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily A3L04_00515 53ceba1fd4b462c64703f0cc6439e856 547 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 61 77 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L04_00515 53ceba1fd4b462c64703f0cc6439e856 547 Gene3D G3DSA:3.30.260.10 147 405 7.7E-220 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A3L04_00515 53ceba1fd4b462c64703f0cc6439e856 547 SUPERFAMILY SSF54849 149 405 2.5E-30 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A3L04_00515 53ceba1fd4b462c64703f0cc6439e856 547 Pfam PF00118 TCP-1/cpn60 chaperonin family 35 525 1.1E-189 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 A3L04_00515 53ceba1fd4b462c64703f0cc6439e856 547 SUPERFAMILY SSF52029 212 378 4.4E-63 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily A3L04_08910 fee4d2cb8fed9a153e14dbb4bce40411 131 Pfam PF01850 PIN domain 3 113 1.1E-7 T 23-10-2018 IPR002716 PIN domain A3L04_08910 fee4d2cb8fed9a153e14dbb4bce40411 131 Gene3D G3DSA:3.40.50.1010 1 122 9.0E-12 T 23-10-2018 A3L04_08910 fee4d2cb8fed9a153e14dbb4bce40411 131 SUPERFAMILY SSF88723 1 120 1.07E-16 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_10160 803916a805ea611a2a785e608d4df79c 289 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 287 78.455 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A3L04_10160 803916a805ea611a2a785e608d4df79c 289 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 3 280 2.0E-83 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A3L04_10160 803916a805ea611a2a785e608d4df79c 289 Pfam PF03186 CobD/Cbib protein 4 263 1.3E-85 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A3L04_05815 5b26ac7dade3c422d5c98a601efe69e0 551 SUPERFAMILY SSF52016 372 550 4.24E-60 T 23-10-2018 A3L04_05815 5b26ac7dade3c422d5c98a601efe69e0 551 Pfam PF00920 Dehydratase family 31 547 3.9E-227 T 23-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A3L04_05815 5b26ac7dade3c422d5c98a601efe69e0 551 SUPERFAMILY SSF143975 1 371 7.32E-145 T 23-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A3L04_05815 5b26ac7dade3c422d5c98a601efe69e0 551 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 550 3.3E-248 T 23-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A3L04_05815 5b26ac7dade3c422d5c98a601efe69e0 551 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 23-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A3L04_05815 5b26ac7dade3c422d5c98a601efe69e0 551 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 550 48.716 T 23-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A3L04_05815 5b26ac7dade3c422d5c98a601efe69e0 551 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 459 470 - T 23-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A3L04_05815 5b26ac7dade3c422d5c98a601efe69e0 551 Gene3D G3DSA:3.50.30.80 372 522 1.7E-54 T 23-10-2018 A3L04_01000 9f1481b0910da249f5dd2671d44883f9 751 Gene3D G3DSA:3.30.70.2230 471 637 5.7E-43 T 23-10-2018 A3L04_01000 9f1481b0910da249f5dd2671d44883f9 751 Pfam PF01966 HD domain 4 91 3.9E-6 T 23-10-2018 IPR006674 HD domain A3L04_01000 9f1481b0910da249f5dd2671d44883f9 751 TIGRFAM TIGR02578 cas_TM1811_Csm1: CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE 7 629 1.3E-110 T 23-10-2018 IPR013408 CRISPR-associated protein Csm1 A3L04_01000 9f1481b0910da249f5dd2671d44883f9 751 Gene3D G3DSA:1.10.3210.10 2 109 3.0E-5 T 23-10-2018 A3L04_01000 9f1481b0910da249f5dd2671d44883f9 751 SUPERFAMILY SSF109604 4 91 3.84E-6 T 23-10-2018 A3L04_01675 e321a8c2eb37064ef3e8ec49eb06a2bf 362 SMART SM00382 28 211 4.7E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_01675 e321a8c2eb37064ef3e8ec49eb06a2bf 362 Gene3D G3DSA:2.40.50.140 282 342 8.3E-38 T 23-10-2018 A3L04_01675 e321a8c2eb37064ef3e8ec49eb06a2bf 362 Gene3D G3DSA:3.40.50.300 1 237 8.0E-82 T 23-10-2018 A3L04_01675 e321a8c2eb37064ef3e8ec49eb06a2bf 362 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_01675 e321a8c2eb37064ef3e8ec49eb06a2bf 362 Gene3D G3DSA:2.40.50.100 239 356 8.3E-38 T 23-10-2018 A3L04_01675 e321a8c2eb37064ef3e8ec49eb06a2bf 362 SUPERFAMILY SSF52540 4 243 1.56E-89 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01675 e321a8c2eb37064ef3e8ec49eb06a2bf 362 SUPERFAMILY SSF50331 237 357 1.25E-17 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L04_01675 e321a8c2eb37064ef3e8ec49eb06a2bf 362 Pfam PF00005 ABC transporter 19 161 3.2E-35 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_04700 26a436313e3e2483331d3928577b3487 564 ProDom PD013790 TOPOISOMERASE ISOMERASE SUBUNIT DNA B VI TYPE II NUCLEOTIDE-BINDING ATP-BINDING 353 546 5.0E-93 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 A3L04_04700 26a436313e3e2483331d3928577b3487 564 TIGRFAM TIGR01052 top6b: DNA topoisomerase VI, B subunit 10 533 1.8E-239 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A3L04_04700 26a436313e3e2483331d3928577b3487 564 Pfam PF09239 Topoisomerase VI B subunit, transducer 354 502 4.8E-57 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 A3L04_04700 26a436313e3e2483331d3928577b3487 564 Hamap MF_00322 Type 2 DNA topoisomerase 6 subunit B [top6B]. 8 549 31.998 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A3L04_04700 26a436313e3e2483331d3928577b3487 564 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 142 4.5E-13 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A3L04_04700 26a436313e3e2483331d3928577b3487 564 PIRSF PIRSF006553 1 564 4.0E-217 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A3L04_04700 26a436313e3e2483331d3928577b3487 564 Gene3D G3DSA:3.30.565.10 1 231 1.7E-68 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A3L04_04700 26a436313e3e2483331d3928577b3487 564 SUPERFAMILY SSF54211 353 513 8.34E-61 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L04_04700 26a436313e3e2483331d3928577b3487 564 SMART SM00387 31 151 4.1E-10 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A3L04_04700 26a436313e3e2483331d3928577b3487 564 Gene3D G3DSA:1.10.8.50 232 305 5.4E-9 T 23-10-2018 A3L04_04700 26a436313e3e2483331d3928577b3487 564 SUPERFAMILY SSF55874 18 228 3.14E-28 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A3L04_04700 26a436313e3e2483331d3928577b3487 564 Gene3D G3DSA:3.30.230.10 353 563 3.6E-71 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 Hamap MF_00054_A Elongation factor G [fusA]. 2 725 44.007 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 Pfam PF00009 Elongation factor Tu GTP binding domain 20 257 6.6E-65 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 20 156 1.1E-21 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 Pfam PF00679 Elongation factor G C-terminus 621 707 1.6E-24 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 Gene3D G3DSA:3.30.230.10 472 721 3.1E-75 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 SUPERFAMILY SSF54211 463 623 1.77E-47 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 Pfam PF14492 Elongation Factor G, domain II 386 459 1.5E-26 T 23-10-2018 A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 SUPERFAMILY SSF54980 386 461 3.96E-23 T 23-10-2018 IPR035647 EF-G domain III/V-like A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 Gene3D G3DSA:3.30.70.240 466 718 3.1E-75 T 23-10-2018 A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 SUPERFAMILY SSF52540 10 261 1.16E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 Gene3D G3DSA:3.30.70.870 388 463 2.4E-28 T 23-10-2018 A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 SMART SM00889 505 619 3.3E-21 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 SUPERFAMILY SSF50447 259 375 6.68E-34 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 Pfam PF03764 Elongation factor G, domain IV 512 618 2.7E-26 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 Gene3D G3DSA:2.40.30.10 259 385 2.9E-27 T 23-10-2018 A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 Pfam PF03144 Elongation factor Tu domain 2 306 372 1.0E-15 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 SUPERFAMILY SSF54980 624 718 2.62E-24 T 23-10-2018 IPR035647 EF-G domain III/V-like A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 TIGRFAM TIGR00490 aEF-2: translation elongation factor aEF-2 3 721 0.0 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 PRINTS PR00315 GTP-binding elongation factor signature 23 36 2.3E-15 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 PRINTS PR00315 GTP-binding elongation factor signature 143 152 2.3E-15 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 PRINTS PR00315 GTP-binding elongation factor signature 67 75 2.3E-15 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 PRINTS PR00315 GTP-binding elongation factor signature 91 101 2.3E-15 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 PRINTS PR00315 GTP-binding elongation factor signature 107 118 2.3E-15 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 SMART SM00838 621 708 9.9E-46 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like A3L04_00250 df93d4dfd34d0dbfb205224d699d93b1 732 Gene3D G3DSA:3.40.50.300 7 222 1.7E-73 T 23-10-2018 A3L04_03945 cc9a67138743bd02ed3e5be2591bd334 324 Gene3D G3DSA:1.20.970.10 2 174 7.2E-115 T 23-10-2018 A3L04_03945 cc9a67138743bd02ed3e5be2591bd334 324 Pfam PF00591 Glycosyl transferase family, a/b domain 66 307 1.4E-83 T 23-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L04_03945 cc9a67138743bd02ed3e5be2591bd334 324 SUPERFAMILY SSF52418 66 309 4.84E-78 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L04_03945 cc9a67138743bd02ed3e5be2591bd334 324 Pfam PF02885 Glycosyl transferase family, helical bundle domain 2 59 3.4E-15 T 23-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L04_03945 cc9a67138743bd02ed3e5be2591bd334 324 Gene3D G3DSA:3.40.1030.10 65 304 7.2E-115 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L04_03945 cc9a67138743bd02ed3e5be2591bd334 324 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 2 319 7.1E-120 T 23-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 A3L04_03945 cc9a67138743bd02ed3e5be2591bd334 324 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 1 321 35.265 T 23-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 A3L04_03945 cc9a67138743bd02ed3e5be2591bd334 324 SUPERFAMILY SSF47648 2 63 5.1E-15 T 23-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L04_10295 d258aaf74684f3a93a51bfadbb292cfa 985 TIGRFAM TIGR00764 lon_rel: putative ATP-dependent protease 1 951 6.2E-285 T 23-10-2018 IPR004663 Lon protease, archaeal GO:0004176|GO:0005524|GO:0030163 A3L04_10295 d258aaf74684f3a93a51bfadbb292cfa 985 Gene3D G3DSA:3.10.28.10 289 473 1.4E-22 T 23-10-2018 IPR027434 Homing endonuclease A3L04_10295 d258aaf74684f3a93a51bfadbb292cfa 985 SUPERFAMILY SSF51294 86 541 1.47E-7 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L04_10295 d258aaf74684f3a93a51bfadbb292cfa 985 Gene3D G3DSA:2.170.16.10 85 201 2.6E-9 T 23-10-2018 A3L04_10295 d258aaf74684f3a93a51bfadbb292cfa 985 SUPERFAMILY SSF54211 763 936 7.59E-43 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L04_10295 d258aaf74684f3a93a51bfadbb292cfa 985 Gene3D G3DSA:1.10.8.60 644 736 6.1E-44 T 23-10-2018 A3L04_10295 d258aaf74684f3a93a51bfadbb292cfa 985 SUPERFAMILY SSF52540 551 737 4.99E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_10295 d258aaf74684f3a93a51bfadbb292cfa 985 Pfam PF14528 LAGLIDADG-like domain 392 482 2.9E-12 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L04_10295 d258aaf74684f3a93a51bfadbb292cfa 985 SUPERFAMILY SSF55608 380 497 9.36E-10 T 23-10-2018 IPR027434 Homing endonuclease A3L04_10295 d258aaf74684f3a93a51bfadbb292cfa 985 Gene3D G3DSA:3.40.50.300 474 643 8.2E-33 T 23-10-2018 A3L04_10295 d258aaf74684f3a93a51bfadbb292cfa 985 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 840 859 3.1E-21 T 23-10-2018 A3L04_10295 d258aaf74684f3a93a51bfadbb292cfa 985 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 893 911 3.1E-21 T 23-10-2018 A3L04_10295 d258aaf74684f3a93a51bfadbb292cfa 985 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 870 889 3.1E-21 T 23-10-2018 A3L04_10295 d258aaf74684f3a93a51bfadbb292cfa 985 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 763 779 3.1E-21 T 23-10-2018 A3L04_10295 d258aaf74684f3a93a51bfadbb292cfa 985 Gene3D G3DSA:3.30.230.10 755 962 1.3E-77 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L04_10295 d258aaf74684f3a93a51bfadbb292cfa 985 Pfam PF13654 AAA domain 546 733 2.4E-18 T 23-10-2018 A3L04_10295 d258aaf74684f3a93a51bfadbb292cfa 985 PRINTS PR00379 Intein signature 170 183 2.4E-12 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_10295 d258aaf74684f3a93a51bfadbb292cfa 985 PRINTS PR00379 Intein signature 435 450 2.4E-12 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_10295 d258aaf74684f3a93a51bfadbb292cfa 985 PRINTS PR00379 Intein signature 291 303 2.4E-12 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_10295 d258aaf74684f3a93a51bfadbb292cfa 985 PRINTS PR00379 Intein signature 393 405 2.4E-12 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_10295 d258aaf74684f3a93a51bfadbb292cfa 985 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 759 938 3.4E-37 T 23-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A3L04_03795 af7b1bcce78039ecdf33e44b731865d9 273 Gene3D G3DSA:3.30.1490.20 97 165 3.7E-27 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L04_03795 af7b1bcce78039ecdf33e44b731865d9 273 TIGRFAM TIGR02144 LysX_arch: lysine biosynthesis enzyme LysX 3 273 5.9E-112 T 23-10-2018 IPR011870 Lysine biosynthesis enzyme LysX GO:0003824|GO:0005524|GO:0009085 A3L04_03795 af7b1bcce78039ecdf33e44b731865d9 273 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 2 267 8.4E-91 T 23-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 A3L04_03795 af7b1bcce78039ecdf33e44b731865d9 273 Gene3D G3DSA:3.30.470.80 166 273 6.5E-40 T 23-10-2018 A3L04_03795 af7b1bcce78039ecdf33e44b731865d9 273 Gene3D G3DSA:3.40.50.20 1 96 2.0E-33 T 23-10-2018 A3L04_03795 af7b1bcce78039ecdf33e44b731865d9 273 SUPERFAMILY SSF52440 2 82 1.15E-20 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L04_03795 af7b1bcce78039ecdf33e44b731865d9 273 Pfam PF08443 RimK-like ATP-grasp domain 83 266 7.6E-25 T 23-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 A3L04_03795 af7b1bcce78039ecdf33e44b731865d9 273 SUPERFAMILY SSF56059 81 269 8.42E-37 T 23-10-2018 A3L04_06305 5fecb7696c3ba1318337ec449133d26c 411 Gene3D G3DSA:3.60.21.10 1 272 4.6E-144 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L04_06305 5fecb7696c3ba1318337ec449133d26c 411 SUPERFAMILY SSF56300 1 328 3.34E-69 T 23-10-2018 A3L04_06305 5fecb7696c3ba1318337ec449133d26c 411 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 233 3.6E-14 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L04_06305 5fecb7696c3ba1318337ec449133d26c 411 Gene3D G3DSA:3.30.110.80 230 327 4.6E-144 T 23-10-2018 A3L04_06305 5fecb7696c3ba1318337ec449133d26c 411 Hamap MF_02044 DNA double-strand break repair protein Mre11 [mre11]. 1 399 24.509 T 23-10-2018 IPR032885 DNA double-strand break repair protein Mre11, archaea-type GO:0006302 A3L04_05985 dee80b79093f0a957f2ce3b3582621b9 500 Gene3D G3DSA:1.10.10.10 1 73 1.0E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_05985 dee80b79093f0a957f2ce3b3582621b9 500 SUPERFAMILY SSF55681 225 497 4.06E-59 T 23-10-2018 A3L04_05985 dee80b79093f0a957f2ce3b3582621b9 500 Hamap MF_00282 Phenylalanine--tRNA ligase alpha subunit [pheS]. 2 497 38.323 T 23-10-2018 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 A3L04_05985 dee80b79093f0a957f2ce3b3582621b9 500 SUPERFAMILY SSF46785 3 110 5.81E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_05985 dee80b79093f0a957f2ce3b3582621b9 500 Gene3D G3DSA:3.30.930.10 194 499 3.1E-92 T 23-10-2018 A3L04_05985 dee80b79093f0a957f2ce3b3582621b9 500 Pfam PF01409 tRNA synthetases class II core domain (F) 224 495 2.8E-83 T 23-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 A3L04_05985 dee80b79093f0a957f2ce3b3582621b9 500 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 173 497 3.2E-94 T 23-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A3L04_09400 b3226262a3f821512a2118e6c03622e1 172 SUPERFAMILY SSF50475 4 161 1.67E-38 T 23-10-2018 A3L04_09400 b3226262a3f821512a2118e6c03622e1 172 Gene3D G3DSA:2.30.110.10 2 163 2.4E-45 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A3L04_09400 b3226262a3f821512a2118e6c03622e1 172 Pfam PF01613 Flavin reductase like domain 9 141 2.9E-22 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A3L04_09400 b3226262a3f821512a2118e6c03622e1 172 SMART SM00903 5 156 2.1E-12 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A3L04_10710 91e54c9e92edfa749f723f4fa8fc8b17 242 Pfam PF02195 ParB-like nuclease domain 22 91 2.6E-8 T 23-10-2018 IPR003115 ParB/Sulfiredoxin A3L04_10710 91e54c9e92edfa749f723f4fa8fc8b17 242 SUPERFAMILY SSF110849 11 241 8.37E-66 T 23-10-2018 IPR036086 ParB/Sulfiredoxin superfamily A3L04_10710 91e54c9e92edfa749f723f4fa8fc8b17 242 Gene3D G3DSA:3.90.1530.10 17 238 2.0E-84 T 23-10-2018 A3L04_10710 91e54c9e92edfa749f723f4fa8fc8b17 242 SMART SM00470 19 114 1.7E-11 T 23-10-2018 IPR003115 ParB/Sulfiredoxin A3L04_10710 91e54c9e92edfa749f723f4fa8fc8b17 242 Gene3D G3DSA:3.30.1760.10 98 227 2.0E-84 T 23-10-2018 IPR023098 ParB-like nuclease, C-terminal A3L04_09455 7e6e4d02dde910160616e03550e45ef8 224 Pfam PF01909 Nucleotidyltransferase domain 12 84 1.5E-9 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L04_09455 7e6e4d02dde910160616e03550e45ef8 224 SUPERFAMILY SSF81301 18 77 2.34E-11 T 23-10-2018 A3L04_09455 7e6e4d02dde910160616e03550e45ef8 224 Gene3D G3DSA:3.30.460.10 8 93 2.3E-7 T 23-10-2018 A3L04_07870 7a197612ae8ab5534b6439d0259b918c 102 Pfam PF00338 Ribosomal protein S10p/S20e 5 98 4.9E-27 T 23-10-2018 IPR027486 Ribosomal protein S10 domain A3L04_07870 7a197612ae8ab5534b6439d0259b918c 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 27 42 - T 23-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_07870 7a197612ae8ab5534b6439d0259b918c 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 1 100 24.83 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_07870 7a197612ae8ab5534b6439d0259b918c 102 TIGRFAM TIGR01046 uS10_euk_arch: ribosomal protein uS10 2 100 1.1E-52 T 23-10-2018 IPR005729 Ribosomal protein S10, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_07870 7a197612ae8ab5534b6439d0259b918c 102 SUPERFAMILY SSF54999 3 100 4.45E-29 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily A3L04_07870 7a197612ae8ab5534b6439d0259b918c 102 PRINTS PR00971 Ribosomal protein S10 family signature 60 74 8.2E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_07870 7a197612ae8ab5534b6439d0259b918c 102 PRINTS PR00971 Ribosomal protein S10 family signature 3 16 8.2E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_07870 7a197612ae8ab5534b6439d0259b918c 102 PRINTS PR00971 Ribosomal protein S10 family signature 38 53 8.2E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_07870 7a197612ae8ab5534b6439d0259b918c 102 SMART SM01403 5 99 5.0E-42 T 23-10-2018 IPR027486 Ribosomal protein S10 domain A3L04_07870 7a197612ae8ab5534b6439d0259b918c 102 Gene3D G3DSA:3.30.70.600 1 101 1.6E-34 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily A3L04_06265 57c164d6b42d4d7a75ea4a2baa800dd2 385 SUPERFAMILY SSF161093 219 383 1.57E-19 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 A3L04_06265 57c164d6b42d4d7a75ea4a2baa800dd2 385 Pfam PF01769 Divalent cation transporter 57 179 4.7E-21 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A3L04_06265 57c164d6b42d4d7a75ea4a2baa800dd2 385 Pfam PF01769 Divalent cation transporter 257 382 5.8E-17 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A3L04_06265 57c164d6b42d4d7a75ea4a2baa800dd2 385 SUPERFAMILY SSF161093 16 183 1.18E-29 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 A3L04_06265 57c164d6b42d4d7a75ea4a2baa800dd2 385 Gene3D G3DSA:1.10.357.20 10 185 2.1E-10 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain A3L04_06265 57c164d6b42d4d7a75ea4a2baa800dd2 385 Gene3D G3DSA:1.10.357.20 211 385 2.1E-9 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain A3L04_05135 be4748fe3720ef884da571fcce8060e9 328 SMART SM00382 28 220 9.7E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_05135 be4748fe3720ef884da571fcce8060e9 328 Pfam PF00005 ABC transporter 20 162 2.0E-34 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_05135 be4748fe3720ef884da571fcce8060e9 328 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 11 305 2.6E-122 T 23-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A3L04_05135 be4748fe3720ef884da571fcce8060e9 328 Pfam PF13732 Domain of unknown function (DUF4162) 217 303 2.2E-9 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 A3L04_05135 be4748fe3720ef884da571fcce8060e9 328 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_05135 be4748fe3720ef884da571fcce8060e9 328 Gene3D G3DSA:3.40.50.300 1 231 5.2E-75 T 23-10-2018 A3L04_05135 be4748fe3720ef884da571fcce8060e9 328 SUPERFAMILY SSF52540 3 224 1.46E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_08860 e535e443b46b8e8c6ec9ecf30332cd4c 413 Gene3D G3DSA:3.90.550.10 1 238 8.8E-73 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_08860 e535e443b46b8e8c6ec9ecf30332cd4c 413 Pfam PF00483 Nucleotidyl transferase 2 231 3.2E-45 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L04_08860 e535e443b46b8e8c6ec9ecf30332cd4c 413 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 312 346 4.2E-5 T 23-10-2018 IPR001451 Hexapeptide repeat A3L04_08860 e535e443b46b8e8c6ec9ecf30332cd4c 413 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 261 287 3.6E-5 T 23-10-2018 IPR001451 Hexapeptide repeat A3L04_08860 e535e443b46b8e8c6ec9ecf30332cd4c 413 SUPERFAMILY SSF53448 1 299 1.92E-74 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_08860 e535e443b46b8e8c6ec9ecf30332cd4c 413 SUPERFAMILY SSF51161 231 395 7.07E-22 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A3L04_08860 e535e443b46b8e8c6ec9ecf30332cd4c 413 Gene3D G3DSA:2.160.10.10 239 378 2.8E-18 T 23-10-2018 A3L04_02895 d419a7e4530ede3fefb604f1b9b7f08f 431 Gene3D G3DSA:3.40.1480.10 262 425 6.2E-169 T 23-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily A3L04_02895 d419a7e4530ede3fefb604f1b9b7f08f 431 SUPERFAMILY SSF82544 2 428 9.68E-133 T 23-10-2018 A3L04_02895 d419a7e4530ede3fefb604f1b9b7f08f 431 Pfam PF13660 Domain of unknown function (DUF4147) 5 236 1.1E-80 T 23-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 A3L04_02895 d419a7e4530ede3fefb604f1b9b7f08f 431 Gene3D G3DSA:3.40.50.10180 21 261 6.2E-169 T 23-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 A3L04_02895 d419a7e4530ede3fefb604f1b9b7f08f 431 Pfam PF05161 MOFRL family 317 421 3.3E-34 T 23-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 A3L04_04355 30b458115ca240e75853eb999f263667 259 SUPERFAMILY SSF56553 38 148 1.57E-29 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04355 30b458115ca240e75853eb999f263667 259 SUPERFAMILY SSF55257 3 255 5.69E-31 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04355 30b458115ca240e75853eb999f263667 259 Hamap MF_00320 DNA-directed RNA polymerase subunit D [rpoD]. 2 256 33.976 T 23-10-2018 IPR022842 DNA-directed RNA polymerase subunit D (Rpo3) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04355 30b458115ca240e75853eb999f263667 259 Gene3D G3DSA:2.170.120.12 39 146 6.9E-97 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04355 30b458115ca240e75853eb999f263667 259 SMART SM00662 13 253 5.3E-96 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04355 30b458115ca240e75853eb999f263667 259 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 45 147 2.0E-28 T 23-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04355 30b458115ca240e75853eb999f263667 259 Gene3D G3DSA:3.30.70.3110 156 217 6.9E-97 T 23-10-2018 A3L04_04355 30b458115ca240e75853eb999f263667 259 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 15 246 1.1E-18 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04355 30b458115ca240e75853eb999f263667 259 Gene3D G3DSA:3.30.1360.10 5 250 6.9E-97 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04355 30b458115ca240e75853eb999f263667 259 ProSitePatterns PS00446 RNA polymerases D / 30 to 40 Kd subunits signature. 27 67 - T 23-10-2018 IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 A3L04_06100 5bff8fbda71d4c68bcc06a23edc8813c 181 PIRSF PIRSF005590 1 179 4.7E-71 T 23-10-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_06100 5bff8fbda71d4c68bcc06a23edc8813c 181 SUPERFAMILY SSF54686 4 167 4.06E-56 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 A3L04_06100 5bff8fbda71d4c68bcc06a23edc8813c 181 Pfam PF00252 Ribosomal protein L16p/L10e 14 160 5.5E-32 T 23-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A3L04_06100 5bff8fbda71d4c68bcc06a23edc8813c 181 ProSitePatterns PS01257 Ribosomal protein L10e signature. 105 126 - T 23-10-2018 IPR018255 Ribosomal protein L10e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_06100 5bff8fbda71d4c68bcc06a23edc8813c 181 Hamap MF_00448 50S ribosomal protein L10e [rpl10e]. 1 174 37.951 T 23-10-2018 IPR022981 Ribosomal protein L10e, archaea A3L04_06100 5bff8fbda71d4c68bcc06a23edc8813c 181 Gene3D G3DSA:3.90.1170.10 1 178 1.8E-66 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 A3L04_00780 a9406c9a867b5a50ca879bdbf5fb6588 154 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 11 151 28.287 T 23-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L04_00780 a9406c9a867b5a50ca879bdbf5fb6588 154 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 15 147 1.3E-46 T 23-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L04_00780 a9406c9a867b5a50ca879bdbf5fb6588 154 Gene3D G3DSA:3.40.50.960 4 153 1.1E-52 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L04_00780 a9406c9a867b5a50ca879bdbf5fb6588 154 SUPERFAMILY SSF52121 7 151 1.57E-51 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L04_00780 a9406c9a867b5a50ca879bdbf5fb6588 154 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 14 148 3.9E-49 T 23-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L04_00015 249d76eae23e1a4082a7b9cf920ba353 632 Gene3D G3DSA:3.90.76.10 42 187 4.7E-204 T 23-10-2018 A3L04_00015 249d76eae23e1a4082a7b9cf920ba353 632 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 612 631 2.6E-7 T 23-10-2018 IPR027552 CGP-CTERM domain A3L04_00015 249d76eae23e1a4082a7b9cf920ba353 632 Gene3D G3DSA:3.40.190.10 29 542 4.7E-204 T 23-10-2018 A3L04_00015 249d76eae23e1a4082a7b9cf920ba353 632 Gene3D G3DSA:3.10.105.10 276 518 4.7E-204 T 23-10-2018 A3L04_00015 249d76eae23e1a4082a7b9cf920ba353 632 SUPERFAMILY SSF53850 28 548 5.43E-116 T 23-10-2018 A3L04_00015 249d76eae23e1a4082a7b9cf920ba353 632 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 75 455 1.1E-73 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain A3L04_04765 74bc8e075b720427edcb4ffcf395d24f 249 SUPERFAMILY SSF55666 155 243 5.37E-26 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L04_04765 74bc8e075b720427edcb4ffcf395d24f 249 Gene3D G3DSA:3.30.230.70 24 249 1.3E-78 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L04_04765 74bc8e075b720427edcb4ffcf395d24f 249 Pfam PF01138 3' exoribonuclease family, domain 1 25 154 2.5E-36 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L04_04765 74bc8e075b720427edcb4ffcf395d24f 249 Pfam PF03725 3' exoribonuclease family, domain 2 157 222 9.8E-17 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L04_04765 74bc8e075b720427edcb4ffcf395d24f 249 SUPERFAMILY SSF54211 8 180 8.1E-47 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L04_04765 74bc8e075b720427edcb4ffcf395d24f 249 Hamap MF_00591 Exosome complex component Rrp41 [rrp41]. 6 242 61.471 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 A3L04_04765 74bc8e075b720427edcb4ffcf395d24f 249 TIGRFAM TIGR02065 ECX1: exosome complex exonuclease 1 9 238 2.7E-121 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 A3L04_06190 fac30ddf36a61676fdb362ed9200569c 295 Gene3D G3DSA:3.90.230.10 8 285 1.0E-110 T 23-10-2018 A3L04_06190 fac30ddf36a61676fdb362ed9200569c 295 ProSitePatterns PS01202 Methionine aminopeptidase subfamily 2 signature. 77 93 - T 23-10-2018 IPR018349 Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L04_06190 fac30ddf36a61676fdb362ed9200569c 295 SUPERFAMILY SSF46785 195 271 5.3E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_06190 fac30ddf36a61676fdb362ed9200569c 295 Hamap MF_01975 Methionine aminopeptidase [map]. 3 294 48.327 T 23-10-2018 IPR028595 Methionine aminopeptidase, archaeal GO:0004177|GO:0006508 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L04_06190 fac30ddf36a61676fdb362ed9200569c 295 TIGRFAM TIGR00501 met_pdase_II: methionine aminopeptidase, type II 3 294 3.4E-115 T 23-10-2018 IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800|Reactome: R-HSA-2514859 A3L04_06190 fac30ddf36a61676fdb362ed9200569c 295 Pfam PF00557 Metallopeptidase family M24 5 286 4.7E-46 T 23-10-2018 IPR000994 Peptidase M24 A3L04_06190 fac30ddf36a61676fdb362ed9200569c 295 Gene3D G3DSA:1.10.10.10 195 271 1.0E-110 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_06190 fac30ddf36a61676fdb362ed9200569c 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 144 156 1.4E-17 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L04_06190 fac30ddf36a61676fdb362ed9200569c 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 77 93 1.4E-17 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L04_06190 fac30ddf36a61676fdb362ed9200569c 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 176 188 1.4E-17 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L04_06190 fac30ddf36a61676fdb362ed9200569c 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 52 65 1.4E-17 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L04_06190 fac30ddf36a61676fdb362ed9200569c 295 SUPERFAMILY SSF55920 2 294 7.07E-69 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like A3L04_02005 1ece77022e9213a8317879883095cde9 159 Pfam PF00137 ATP synthase subunit C 97 155 4.3E-16 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A3L04_02005 1ece77022e9213a8317879883095cde9 159 Pfam PF00137 ATP synthase subunit C 9 68 5.1E-11 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A3L04_02005 1ece77022e9213a8317879883095cde9 159 SUPERFAMILY SSF81333 5 68 2.09E-9 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily A3L04_02005 1ece77022e9213a8317879883095cde9 159 Gene3D G3DSA:1.20.120.610 1 158 2.4E-37 T 23-10-2018 A3L04_02005 1ece77022e9213a8317879883095cde9 159 SUPERFAMILY SSF81333 89 157 7.45E-14 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily A3L04_01065 78b8ddede88854c3f80ab9f5bccf3cc3 689 Gene3D G3DSA:3.40.50.300 218 380 6.8E-8 T 23-10-2018 A3L04_01065 78b8ddede88854c3f80ab9f5bccf3cc3 689 Pfam PF01966 HD domain 20 138 6.2E-7 T 23-10-2018 IPR006674 HD domain A3L04_01065 78b8ddede88854c3f80ab9f5bccf3cc3 689 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 19 181 9.0E-22 T 23-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain A3L04_01065 78b8ddede88854c3f80ab9f5bccf3cc3 689 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 228 522 6.9E-69 T 23-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core A3L04_01065 78b8ddede88854c3f80ab9f5bccf3cc3 689 SUPERFAMILY SSF52540 223 528 1.07E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01065 78b8ddede88854c3f80ab9f5bccf3cc3 689 SMART SM00490 437 515 2.1E-11 T 23-10-2018 IPR001650 Helicase, C-terminal A3L04_01065 78b8ddede88854c3f80ab9f5bccf3cc3 689 SUPERFAMILY SSF109604 17 107 1.76E-6 T 23-10-2018 A3L04_01065 78b8ddede88854c3f80ab9f5bccf3cc3 689 Gene3D G3DSA:1.10.3210.30 4 163 2.7E-13 T 23-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily A3L04_01065 78b8ddede88854c3f80ab9f5bccf3cc3 689 SMART SM00487 206 406 3.7E-11 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L04_01065 78b8ddede88854c3f80ab9f5bccf3cc3 689 Pfam PF00271 Helicase conserved C-terminal domain 416 515 2.5E-8 T 23-10-2018 IPR001650 Helicase, C-terminal A3L04_01065 78b8ddede88854c3f80ab9f5bccf3cc3 689 Gene3D G3DSA:3.40.50.300 381 555 3.4E-21 T 23-10-2018 A3L04_01215 b332f951605c49f9d1d41af7aacf32b3 285 Gene3D G3DSA:3.40.800.10 4 283 1.3E-73 T 23-10-2018 A3L04_01215 b332f951605c49f9d1d41af7aacf32b3 285 Pfam PF00491 Arginase family 22 278 1.8E-60 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L04_01215 b332f951605c49f9d1d41af7aacf32b3 285 SUPERFAMILY SSF52768 15 281 1.98E-70 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily A3L04_01215 b332f951605c49f9d1d41af7aacf32b3 285 PIRSF PIRSF036979 1 284 1.6E-88 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L04_01215 b332f951605c49f9d1d41af7aacf32b3 285 TIGRFAM TIGR01230 agmatinase: agmatinase 18 279 8.6E-67 T 23-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 A3L04_07795 f44c60fe0be4eacab889f8280bc191be 136 SUPERFAMILY SSF82784 8 133 5.76E-32 T 23-10-2018 IPR036102 OsmC/Ohr superfamily A3L04_07795 f44c60fe0be4eacab889f8280bc191be 136 Pfam PF02566 OsmC-like protein 32 119 1.0E-14 T 23-10-2018 IPR003718 OsmC/Ohr family A3L04_07795 f44c60fe0be4eacab889f8280bc191be 136 Gene3D G3DSA:3.30.300.20 3 134 5.0E-33 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L04_07860 55789d070a2ee7ad6843989682386d90 300 PRINTS PR00685 Transcription initiation factor IIB signature 41 54 2.5E-64 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L04_07860 55789d070a2ee7ad6843989682386d90 300 PRINTS PR00685 Transcription initiation factor IIB signature 54 75 2.5E-64 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L04_07860 55789d070a2ee7ad6843989682386d90 300 PRINTS PR00685 Transcription initiation factor IIB signature 19 39 2.5E-64 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L04_07860 55789d070a2ee7ad6843989682386d90 300 PRINTS PR00685 Transcription initiation factor IIB signature 245 261 2.5E-64 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L04_07860 55789d070a2ee7ad6843989682386d90 300 PRINTS PR00685 Transcription initiation factor IIB signature 182 197 2.5E-64 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L04_07860 55789d070a2ee7ad6843989682386d90 300 PRINTS PR00685 Transcription initiation factor IIB signature 211 229 2.5E-64 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L04_07860 55789d070a2ee7ad6843989682386d90 300 PRINTS PR00685 Transcription initiation factor IIB signature 156 175 2.5E-64 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L04_07860 55789d070a2ee7ad6843989682386d90 300 PRINTS PR00685 Transcription initiation factor IIB signature 277 291 2.5E-64 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L04_07860 55789d070a2ee7ad6843989682386d90 300 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 1 297 45.77 T 23-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea A3L04_07860 55789d070a2ee7ad6843989682386d90 300 SUPERFAMILY SSF47954 206 298 2.11E-31 T 23-10-2018 IPR036915 Cyclin-like superfamily A3L04_07860 55789d070a2ee7ad6843989682386d90 300 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 148 163 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L04_07860 55789d070a2ee7ad6843989682386d90 300 SUPERFAMILY SSF57783 4 50 7.65E-19 T 23-10-2018 A3L04_07860 55789d070a2ee7ad6843989682386d90 300 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 244 259 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L04_07860 55789d070a2ee7ad6843989682386d90 300 Gene3D G3DSA:1.10.472.10 207 300 6.0E-30 T 23-10-2018 A3L04_07860 55789d070a2ee7ad6843989682386d90 300 Gene3D G3DSA:1.10.472.170 6 197 1.5E-68 T 23-10-2018 A3L04_07860 55789d070a2ee7ad6843989682386d90 300 SUPERFAMILY SSF47954 113 200 2.76E-27 T 23-10-2018 IPR036915 Cyclin-like superfamily A3L04_07860 55789d070a2ee7ad6843989682386d90 300 SMART SM00385 114 195 7.3E-12 T 23-10-2018 IPR013763 Cyclin-like A3L04_07860 55789d070a2ee7ad6843989682386d90 300 SMART SM00385 210 291 2.2E-14 T 23-10-2018 IPR013763 Cyclin-like A3L04_07860 55789d070a2ee7ad6843989682386d90 300 Pfam PF00382 Transcription factor TFIIB repeat 117 186 1.4E-20 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A3L04_07860 55789d070a2ee7ad6843989682386d90 300 Pfam PF00382 Transcription factor TFIIB repeat 212 282 3.0E-24 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A3L04_07860 55789d070a2ee7ad6843989682386d90 300 Pfam PF08271 TFIIB zinc-binding 6 47 1.7E-20 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type A3L04_09950 31e498060247ec1c605968e344a7c58e 392 Gene3D G3DSA:3.90.1150.10 33 382 2.3E-137 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L04_09950 31e498060247ec1c605968e344a7c58e 392 SUPERFAMILY SSF53383 12 389 2.13E-123 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L04_09950 31e498060247ec1c605968e344a7c58e 392 Pfam PF00155 Aminotransferase class I and II 33 383 5.7E-76 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L04_09950 31e498060247ec1c605968e344a7c58e 392 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 233 246 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A3L04_09950 31e498060247ec1c605968e344a7c58e 392 Gene3D G3DSA:3.40.640.10 64 283 2.3E-137 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L04_01810 69bf3c29aba2659ca9570e91f5ef9fcb 385 SUPERFAMILY SSF103473 5 383 2.35E-48 T 23-10-2018 IPR036259 MFS transporter superfamily A3L04_01810 69bf3c29aba2659ca9570e91f5ef9fcb 385 Pfam PF07690 Major Facilitator Superfamily 215 382 1.5E-10 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L04_01810 69bf3c29aba2659ca9570e91f5ef9fcb 385 Pfam PF07690 Major Facilitator Superfamily 9 201 2.4E-15 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L04_01810 69bf3c29aba2659ca9570e91f5ef9fcb 385 Gene3D G3DSA:1.20.1250.20 5 198 3.1E-18 T 23-10-2018 A3L04_01810 69bf3c29aba2659ca9570e91f5ef9fcb 385 Gene3D G3DSA:1.20.1250.20 206 385 2.7E-17 T 23-10-2018 A3L04_01240 a4f81134800520cf55aa8011dbc46dc5 61 SUPERFAMILY SSF56574 12 57 2.62E-7 T 23-10-2018 IPR036186 Serpin superfamily A3L04_01240 a4f81134800520cf55aa8011dbc46dc5 61 Gene3D G3DSA:3.30.497.10 1 61 9.4E-11 T 23-10-2018 A3L04_01240 a4f81134800520cf55aa8011dbc46dc5 61 Pfam PF00079 Serpin (serine protease inhibitor) 11 59 3.3E-7 T 23-10-2018 IPR023796 Serpin domain A3L04_04010 cf5c8d2870cdfa1dce803743ea8a9d74 424 Pfam PF04055 Radical SAM superfamily 168 338 4.5E-26 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_04010 cf5c8d2870cdfa1dce803743ea8a9d74 424 SUPERFAMILY SSF102114 159 377 2.49E-39 T 23-10-2018 A3L04_04010 cf5c8d2870cdfa1dce803743ea8a9d74 424 TIGRFAM TIGR04013 B12_SAM_MJ_1487: B12-binding domain/radical SAM domain protein, MJ_1487 family 4 392 4.8E-146 T 23-10-2018 IPR023980 Conserved hypothetical protein CHP04013, B12-binding/radical SAM-type A3L04_04010 cf5c8d2870cdfa1dce803743ea8a9d74 424 Gene3D G3DSA:3.80.30.20 164 389 6.6E-38 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L04_04010 cf5c8d2870cdfa1dce803743ea8a9d74 424 Pfam PF02310 B12 binding domain 18 112 1.9E-14 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A3L04_04010 cf5c8d2870cdfa1dce803743ea8a9d74 424 SMART SM00729 164 382 2.3E-49 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L04_04010 cf5c8d2870cdfa1dce803743ea8a9d74 424 Gene3D G3DSA:3.40.50.280 2 128 4.3E-26 T 23-10-2018 A3L04_05050 8f1e9b44739e03a4613b08e51127f0ce 440 Gene3D G3DSA:3.50.50.60 107 431 6.6E-149 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_05050 8f1e9b44739e03a4613b08e51127f0ce 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 3.5E-24 T 23-10-2018 A3L04_05050 8f1e9b44739e03a4613b08e51127f0ce 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 3.5E-24 T 23-10-2018 A3L04_05050 8f1e9b44739e03a4613b08e51127f0ce 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 3.5E-24 T 23-10-2018 A3L04_05050 8f1e9b44739e03a4613b08e51127f0ce 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 3.5E-24 T 23-10-2018 A3L04_05050 8f1e9b44739e03a4613b08e51127f0ce 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 3.5E-24 T 23-10-2018 A3L04_05050 8f1e9b44739e03a4613b08e51127f0ce 440 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 296 1.4E-68 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L04_05050 8f1e9b44739e03a4613b08e51127f0ce 440 SUPERFAMILY SSF51905 1 191 1.08E-47 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_05050 8f1e9b44739e03a4613b08e51127f0ce 440 Gene3D G3DSA:3.50.50.60 2 331 6.6E-149 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_05050 8f1e9b44739e03a4613b08e51127f0ce 440 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 324 423 5.0E-18 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A3L04_05050 8f1e9b44739e03a4613b08e51127f0ce 440 SUPERFAMILY SSF51905 142 307 1.84E-34 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_05050 8f1e9b44739e03a4613b08e51127f0ce 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 2.8E-17 T 23-10-2018 A3L04_05050 8f1e9b44739e03a4613b08e51127f0ce 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 170 2.8E-17 T 23-10-2018 A3L04_05050 8f1e9b44739e03a4613b08e51127f0ce 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 2.8E-17 T 23-10-2018 A3L04_05050 8f1e9b44739e03a4613b08e51127f0ce 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 2.8E-17 T 23-10-2018 A3L04_05050 8f1e9b44739e03a4613b08e51127f0ce 440 SUPERFAMILY SSF55424 316 437 2.23E-29 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A3L04_10485 14929fee1c191e0a429b6459237987cb 138 SUPERFAMILY SSF55021 53 133 2.59E-29 T 23-10-2018 A3L04_10485 14929fee1c191e0a429b6459237987cb 138 Gene3D G3DSA:1.10.1220.10 10 50 8.9E-23 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A3L04_10485 14929fee1c191e0a429b6459237987cb 138 SUPERFAMILY SSF47598 2 47 1.48E-14 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A3L04_10485 14929fee1c191e0a429b6459237987cb 138 Hamap MF_00476 Nickel-responsive regulator [nikR]. 3 133 31.233 T 23-10-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 A3L04_10485 14929fee1c191e0a429b6459237987cb 138 Pfam PF01402 Ribbon-helix-helix protein, copG family 5 43 3.7E-9 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A3L04_10485 14929fee1c191e0a429b6459237987cb 138 Pfam PF08753 NikR C terminal nickel binding domain 55 131 2.5E-33 T 23-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal A3L04_10485 14929fee1c191e0a429b6459237987cb 138 Gene3D G3DSA:3.30.70.1150 51 138 6.2E-38 T 23-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal A3L04_02570 e3529b19d35706784d9bfb67cbb9771e 371 Gene3D G3DSA:1.10.580.10 19 343 1.6E-134 T 23-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A3L04_02570 e3529b19d35706784d9bfb67cbb9771e 371 Pfam PF00285 Citrate synthase, C-terminal domain 7 354 1.1E-126 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 A3L04_02570 e3529b19d35706784d9bfb67cbb9771e 371 Gene3D G3DSA:1.10.230.10 221 318 1.6E-134 T 23-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain A3L04_02570 e3529b19d35706784d9bfb67cbb9771e 371 SUPERFAMILY SSF48256 6 371 3.93E-134 T 23-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 A3L04_02570 e3529b19d35706784d9bfb67cbb9771e 371 PRINTS PR00143 Citrate synthase signature 248 268 1.0E-42 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 A3L04_02570 e3529b19d35706784d9bfb67cbb9771e 371 PRINTS PR00143 Citrate synthase signature 173 188 1.0E-42 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 A3L04_02570 e3529b19d35706784d9bfb67cbb9771e 371 PRINTS PR00143 Citrate synthase signature 324 338 1.0E-42 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 A3L04_02570 e3529b19d35706784d9bfb67cbb9771e 371 PRINTS PR00143 Citrate synthase signature 195 223 1.0E-42 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 A3L04_02570 e3529b19d35706784d9bfb67cbb9771e 371 PRINTS PR00143 Citrate synthase signature 304 320 1.0E-42 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 A3L04_02570 e3529b19d35706784d9bfb67cbb9771e 371 PRINTS PR00143 Citrate synthase signature 124 137 1.0E-42 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 A3L04_02570 e3529b19d35706784d9bfb67cbb9771e 371 ProSitePatterns PS00480 Citrate synthase signature. 255 267 - T 23-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A3L04_02570 e3529b19d35706784d9bfb67cbb9771e 371 PIRSF PIRSF001369 1 371 8.9E-137 T 23-10-2018 IPR024176 Citrate synthase, bacterial-type A3L04_02570 e3529b19d35706784d9bfb67cbb9771e 371 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 6 371 2.5E-158 T 23-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 A3L04_04210 e961f0308cb1725d359ceae972e139be 91 SMART SM01152 5 80 1.2E-31 T 23-10-2018 IPR003746 Protein of unknown function DUF167 A3L04_04210 e961f0308cb1725d359ceae972e139be 91 SUPERFAMILY SSF69786 2 89 4.32E-27 T 23-10-2018 IPR036591 YggU-like superfamily A3L04_04210 e961f0308cb1725d359ceae972e139be 91 TIGRFAM TIGR00251 TIGR00251: TIGR00251 family protein 2 79 5.1E-28 T 23-10-2018 IPR005228 Conserved hypothetical protein CHP00251 A3L04_04210 e961f0308cb1725d359ceae972e139be 91 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 9 78 1.3E-24 T 23-10-2018 IPR003746 Protein of unknown function DUF167 A3L04_04210 e961f0308cb1725d359ceae972e139be 91 Hamap MF_00634 UPF0235 protein YggU [yggU]. 5 91 19.996 T 23-10-2018 IPR003746 Protein of unknown function DUF167 A3L04_04210 e961f0308cb1725d359ceae972e139be 91 Gene3D G3DSA:3.30.1200.10 1 91 1.2E-31 T 23-10-2018 IPR036591 YggU-like superfamily A3L04_03905 3efff703830e1f1dde25a503f791e1d7 76 SUPERFAMILY SSF48600 4 74 1.68E-19 T 23-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A3L04_03905 3efff703830e1f1dde25a503f791e1d7 76 TIGRFAM TIGR01808 CM_M_hiGC-arch: chorismate mutase 4 72 1.5E-23 T 23-10-2018 IPR010958 Chorismate mutase, high GC Gram-positive bacteria/archaeal A3L04_03905 3efff703830e1f1dde25a503f791e1d7 76 SMART SM00830 8 76 9.1E-19 T 23-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A3L04_03905 3efff703830e1f1dde25a503f791e1d7 76 Pfam PF01817 Chorismate mutase type II 8 74 1.5E-18 T 23-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A3L04_03905 3efff703830e1f1dde25a503f791e1d7 76 Gene3D G3DSA:1.20.59.10 1 76 1.2E-28 T 23-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A3L04_05965 c6540c1ae9eb089f78d1a4bd388aca2f 110 ProSitePatterns PS00466 Zinc finger TFIIS-type signature. 71 106 - T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 A3L04_05965 c6540c1ae9eb089f78d1a4bd388aca2f 110 SMART SM00661 3 56 1.7E-19 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 A3L04_05965 c6540c1ae9eb089f78d1a4bd388aca2f 110 SUPERFAMILY SSF57783 48 109 1.98E-21 T 23-10-2018 A3L04_05965 c6540c1ae9eb089f78d1a4bd388aca2f 110 SUPERFAMILY SSF57783 2 34 8.5E-5 T 23-10-2018 A3L04_05965 c6540c1ae9eb089f78d1a4bd388aca2f 110 Gene3D G3DSA:2.20.25.10 55 110 1.3E-24 T 23-10-2018 A3L04_05965 c6540c1ae9eb089f78d1a4bd388aca2f 110 PIRSF PIRSF005586 2 110 2.6E-37 T 23-10-2018 IPR012164 DNA-directed RNA polymerase subunit/transcription factor S GO:0006351 A3L04_05965 c6540c1ae9eb089f78d1a4bd388aca2f 110 SMART SM00440 69 108 2.8E-20 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 A3L04_05965 c6540c1ae9eb089f78d1a4bd388aca2f 110 Pfam PF01096 Transcription factor S-II (TFIIS) 70 107 2.9E-19 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 A3L04_05965 c6540c1ae9eb089f78d1a4bd388aca2f 110 ProSitePatterns PS01030 RNA polymerases M / 15 Kd subunits signature. 4 26 - T 23-10-2018 IPR019761 DNA-directed RNA polymerase M, 15kDa subunit, conserved site A3L04_05965 c6540c1ae9eb089f78d1a4bd388aca2f 110 TIGRFAM TIGR01384 TFS_arch: transcription factor S 3 110 6.1E-42 T 23-10-2018 IPR006288 Transcription factor S GO:0006355 A3L04_05965 c6540c1ae9eb089f78d1a4bd388aca2f 110 Pfam PF02150 RNA polymerases M/15 Kd subunit 2 33 1.0E-11 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 A3L04_03270 d79ace28822c929466f15c72fbb81ff9 1173 Gene3D G3DSA:3.40.50.300 1005 1173 4.9E-61 T 23-10-2018 A3L04_03270 d79ace28822c929466f15c72fbb81ff9 1173 TIGRFAM TIGR02169 SMC_prok_A: chromosome segregation protein SMC 3 1157 0.0 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A3L04_03270 d79ace28822c929466f15c72fbb81ff9 1173 SUPERFAMILY SSF75553 480 676 3.27E-49 T 23-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 A3L04_03270 d79ace28822c929466f15c72fbb81ff9 1173 SUPERFAMILY SSF57997 379 509 1.9E-7 T 23-10-2018 A3L04_03270 d79ace28822c929466f15c72fbb81ff9 1173 PIRSF PIRSF005719 1 1163 6.9E-280 T 23-10-2018 IPR024704 Structural maintenance of chromosomes protein A3L04_03270 d79ace28822c929466f15c72fbb81ff9 1173 Pfam PF06470 SMC proteins Flexible Hinge Domain 520 627 2.6E-32 T 23-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A3L04_03270 d79ace28822c929466f15c72fbb81ff9 1173 Gene3D G3DSA:1.20.5.340 776 871 2.5E-5 T 23-10-2018 A3L04_03270 d79ace28822c929466f15c72fbb81ff9 1173 Gene3D G3DSA:3.40.50.300 2 234 6.6E-64 T 23-10-2018 A3L04_03270 d79ace28822c929466f15c72fbb81ff9 1173 Gene3D G3DSA:3.30.70.1620 581 655 4.6E-43 T 23-10-2018 A3L04_03270 d79ace28822c929466f15c72fbb81ff9 1173 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1150 1.5E-70 T 23-10-2018 IPR003395 RecF/RecN/SMC, N-terminal A3L04_03270 d79ace28822c929466f15c72fbb81ff9 1173 SMART SM00968 520 630 1.6E-42 T 23-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A3L04_03270 d79ace28822c929466f15c72fbb81ff9 1173 Gene3D G3DSA:1.20.1060.20 506 657 4.6E-43 T 23-10-2018 A3L04_03270 d79ace28822c929466f15c72fbb81ff9 1173 Hamap MF_01894 Chromosome partition protein Smc [smc]. 2 1159 21.738 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A3L04_03270 d79ace28822c929466f15c72fbb81ff9 1173 SUPERFAMILY SSF52540 1 1165 3.89E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_03270 d79ace28822c929466f15c72fbb81ff9 1173 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1157 9.5E-236 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A3L04_03215 6eb52ccaadaf30d039037f70ca1d246e 348 PRINTS PR00419 Adrenodoxin reductase family signature 39 52 3.7E-16 T 23-10-2018 A3L04_03215 6eb52ccaadaf30d039037f70ca1d246e 348 PRINTS PR00419 Adrenodoxin reductase family signature 16 38 3.7E-16 T 23-10-2018 A3L04_03215 6eb52ccaadaf30d039037f70ca1d246e 348 PRINTS PR00419 Adrenodoxin reductase family signature 169 183 3.7E-16 T 23-10-2018 A3L04_03215 6eb52ccaadaf30d039037f70ca1d246e 348 Gene3D G3DSA:3.50.50.60 152 266 1.5E-15 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_03215 6eb52ccaadaf30d039037f70ca1d246e 348 SUPERFAMILY SSF51971 14 270 2.77E-55 T 23-10-2018 A3L04_03215 6eb52ccaadaf30d039037f70ca1d246e 348 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 307 1.1E-29 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L04_03215 6eb52ccaadaf30d039037f70ca1d246e 348 Gene3D G3DSA:3.50.50.60 13 151 4.8E-25 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_03805 380054ab30d8c1828fc880c90901a4f2 249 TIGRFAM TIGR00761 argB: acetylglutamate kinase 1 239 7.6E-65 T 23-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A3L04_03805 380054ab30d8c1828fc880c90901a4f2 249 PIRSF PIRSF000728 1 248 2.3E-55 T 23-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A3L04_03805 380054ab30d8c1828fc880c90901a4f2 249 Hamap MF_02082 [LysW]-aminoadipate/[LysW]-glutamate kinase [lysZ]. 1 249 43.886 T 23-10-2018 IPR037529 [LysW]-aminoadipate/[LysW]-glutamate kinase GO:0016301 A3L04_03805 380054ab30d8c1828fc880c90901a4f2 249 SUPERFAMILY SSF53633 2 241 1.09E-35 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L04_03805 380054ab30d8c1828fc880c90901a4f2 249 Pfam PF00696 Amino acid kinase family 2 239 7.3E-28 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A3L04_03805 380054ab30d8c1828fc880c90901a4f2 249 Gene3D G3DSA:3.40.1160.10 2 248 8.5E-45 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L04_06570 062acddd6c6e95e7b15ac04aef7e17b9 214 Gene3D G3DSA:1.20.910.10 1 214 1.6E-63 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A3L04_06570 062acddd6c6e95e7b15ac04aef7e17b9 214 Pfam PF03070 TENA/THI-4/PQQC family 8 209 4.2E-46 T 23-10-2018 IPR004305 Thiaminase-2/PQQC A3L04_06570 062acddd6c6e95e7b15ac04aef7e17b9 214 SUPERFAMILY SSF48613 2 210 9.64E-64 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A3L04_06570 062acddd6c6e95e7b15ac04aef7e17b9 214 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 11 209 3.0E-41 T 23-10-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 A3L04_08235 82776499f896391111d03f23bbcbcf4f 359 Gene3D G3DSA:3.40.50.300 1 203 5.6E-39 T 23-10-2018 A3L04_08235 82776499f896391111d03f23bbcbcf4f 359 Pfam PF01637 ATPase domain predominantly from Archaea 16 244 2.0E-16 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_08235 82776499f896391111d03f23bbcbcf4f 359 Gene3D G3DSA:1.10.8.60 205 280 2.8E-23 T 23-10-2018 A3L04_08235 82776499f896391111d03f23bbcbcf4f 359 SUPERFAMILY SSF52540 1 278 4.0E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_08235 82776499f896391111d03f23bbcbcf4f 359 SUPERFAMILY SSF46785 283 357 1.54E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_08235 82776499f896391111d03f23bbcbcf4f 359 Gene3D G3DSA:1.10.10.10 281 358 7.0E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_06300 98f985362e81c25861b68e6cad5f39c6 549 Gene3D G3DSA:3.40.50.300 109 258 1.2E-7 T 23-10-2018 A3L04_06300 98f985362e81c25861b68e6cad5f39c6 549 Pfam PF01935 Domain of unknown function DUF87 134 359 1.1E-51 T 23-10-2018 IPR002789 Helicase HerA, central domain A3L04_06300 98f985362e81c25861b68e6cad5f39c6 549 SUPERFAMILY SSF52540 128 513 1.22E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_06300 98f985362e81c25861b68e6cad5f39c6 549 Gene3D G3DSA:3.40.50.300 310 521 7.6E-55 T 23-10-2018 A3L04_06300 98f985362e81c25861b68e6cad5f39c6 549 Pfam PF05872 Bacterial protein of unknown function (DUF853) 403 496 1.9E-4 T 23-10-2018 IPR033186 Helicase HerA-like C-terminal A3L04_06300 98f985362e81c25861b68e6cad5f39c6 549 Pfam PF09378 HAS barrel domain 8 98 3.4E-16 T 23-10-2018 IPR018538 Helicase HerA, barrel domain A3L04_09430 55e240304ce5cb7d3646434cf456e88e 380 Gene3D G3DSA:3.40.630.10 15 366 2.3E-143 T 23-10-2018 A3L04_09430 55e240304ce5cb7d3646434cf456e88e 380 SUPERFAMILY SSF55031 178 286 3.27E-32 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A3L04_09430 55e240304ce5cb7d3646434cf456e88e 380 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 15 369 2.8E-115 T 23-10-2018 IPR017439 Amidohydrolase GO:0016787 A3L04_09430 55e240304ce5cb7d3646434cf456e88e 380 Gene3D G3DSA:3.30.70.360 177 291 2.3E-143 T 23-10-2018 A3L04_09430 55e240304ce5cb7d3646434cf456e88e 380 Pfam PF07687 Peptidase dimerisation domain 178 279 2.8E-12 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A3L04_09430 55e240304ce5cb7d3646434cf456e88e 380 PIRSF PIRSF005962 1 380 3.5E-136 T 23-10-2018 IPR017439 Amidohydrolase GO:0016787 A3L04_09430 55e240304ce5cb7d3646434cf456e88e 380 Pfam PF01546 Peptidase family M20/M25/M40 69 371 1.3E-36 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A3L04_09430 55e240304ce5cb7d3646434cf456e88e 380 SUPERFAMILY SSF53187 5 379 2.27E-87 T 23-10-2018 A3L04_06315 f03be6b7f6fe7fcba687e7b303957dfc 449 PIRSF PIRSF018871 10 449 1.5E-178 T 23-10-2018 IPR016738 DNA double-strand break repair nuclease NurA-like A3L04_06315 f03be6b7f6fe7fcba687e7b303957dfc 449 SMART SM00933 46 414 4.5E-22 T 23-10-2018 IPR018977 NurA domain A3L04_06315 f03be6b7f6fe7fcba687e7b303957dfc 449 Pfam PF09376 NurA domain 47 414 9.3E-53 T 23-10-2018 IPR018977 NurA domain A3L04_05335 14c6bd40f15b7bf60df912a378b1e27d 175 SUPERFAMILY SSF50199 27 173 1.83E-38 T 23-10-2018 A3L04_05335 14c6bd40f15b7bf60df912a378b1e27d 175 SMART SM00318 29 174 2.4E-49 T 23-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 A3L04_05335 14c6bd40f15b7bf60df912a378b1e27d 175 ProSitePatterns PS01123 Thermonuclease family signature 1. 40 65 - T 23-10-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 A3L04_05335 14c6bd40f15b7bf60df912a378b1e27d 175 Gene3D G3DSA:2.40.50.90 26 175 1.9E-39 T 23-10-2018 IPR035437 SNase-like, OB-fold superfamily A3L04_05335 14c6bd40f15b7bf60df912a378b1e27d 175 ProSitePatterns PS01284 Thermonuclease family signature 2. 117 127 - T 23-10-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 A3L04_05335 14c6bd40f15b7bf60df912a378b1e27d 175 Pfam PF00565 Staphylococcal nuclease homologue 55 172 4.7E-28 T 23-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 A3L04_09760 fb680c9faf3c3e9bc9ad1766655611a9 332 SUPERFAMILY SSF46785 265 328 7.76E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_09760 fb680c9faf3c3e9bc9ad1766655611a9 332 Pfam PF13412 Winged helix-turn-helix DNA-binding 265 312 5.0E-9 T 23-10-2018 A3L04_09760 fb680c9faf3c3e9bc9ad1766655611a9 332 Gene3D G3DSA:1.10.10.10 244 325 2.0E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_09760 fb680c9faf3c3e9bc9ad1766655611a9 332 Pfam PF04122 Putative cell wall binding repeat 2 105 182 6.6E-6 T 23-10-2018 IPR007253 Putative cell wall binding repeat 2 A3L04_01125 5d0705c72b67fdc69ee0e3d5010d61e4 184 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 182 27.795 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A3L04_01125 5d0705c72b67fdc69ee0e3d5010d61e4 184 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 182 1.8E-55 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A3L04_01125 5d0705c72b67fdc69ee0e3d5010d61e4 184 Pfam PF02834 LigT like Phosphoesterase 7 91 2.2E-19 T 23-10-2018 IPR014051 Phosphoesterase, HXTX A3L04_01125 5d0705c72b67fdc69ee0e3d5010d61e4 184 Pfam PF02834 LigT like Phosphoesterase 98 174 6.8E-13 T 23-10-2018 IPR014051 Phosphoesterase, HXTX A3L04_01125 5d0705c72b67fdc69ee0e3d5010d61e4 184 Gene3D G3DSA:3.90.1140.10 1 184 1.7E-68 T 23-10-2018 A3L04_01125 5d0705c72b67fdc69ee0e3d5010d61e4 184 SUPERFAMILY SSF55144 1 182 2.09E-46 T 23-10-2018 IPR009097 Cyclic phosphodiesterase A3L04_05520 d09ba6c2583ed0595a78cce512fe034c 350 Gene3D G3DSA:1.10.10.10 281 350 5.4E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_05520 d09ba6c2583ed0595a78cce512fe034c 350 SUPERFAMILY SSF46785 278 348 4.54E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_05520 d09ba6c2583ed0595a78cce512fe034c 350 Gene3D G3DSA:1.10.8.60 203 280 1.3E-27 T 23-10-2018 A3L04_05520 d09ba6c2583ed0595a78cce512fe034c 350 SUPERFAMILY SSF52540 2 277 1.73E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_05520 d09ba6c2583ed0595a78cce512fe034c 350 Pfam PF01637 ATPase domain predominantly from Archaea 15 243 8.3E-26 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_05520 d09ba6c2583ed0595a78cce512fe034c 350 Gene3D G3DSA:3.40.50.300 1 202 2.2E-53 T 23-10-2018 A3L04_00135 cb64ddc37d28d42aa77d9fea0ee727bd 341 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 160 205 4.5E-7 T 23-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 A3L04_00135 cb64ddc37d28d42aa77d9fea0ee727bd 341 SUPERFAMILY SSF51735 3 142 4.02E-46 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_00135 cb64ddc37d28d42aa77d9fea0ee727bd 341 SUPERFAMILY SSF55347 158 306 1.31E-21 T 23-10-2018 A3L04_00135 cb64ddc37d28d42aa77d9fea0ee727bd 341 Gene3D G3DSA:3.40.50.720 5 311 2.1E-81 T 23-10-2018 A3L04_00135 cb64ddc37d28d42aa77d9fea0ee727bd 341 Gene3D G3DSA:3.30.360.10 125 324 2.1E-81 T 23-10-2018 A3L04_00135 cb64ddc37d28d42aa77d9fea0ee727bd 341 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 124 1.2E-30 T 23-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A3L04_09015 b28cb61294bf76dca913c00d3700b9d1 85 Gene3D G3DSA:3.30.70.240 1 66 2.3E-29 T 23-10-2018 A3L04_09015 b28cb61294bf76dca913c00d3700b9d1 85 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 85 15.535 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 A3L04_09015 b28cb61294bf76dca913c00d3700b9d1 85 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 67 2.2E-12 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 A3L04_09015 b28cb61294bf76dca913c00d3700b9d1 85 SUPERFAMILY SSF143430 1 80 1.7E-23 T 23-10-2018 A3L04_09015 b28cb61294bf76dca913c00d3700b9d1 85 Pfam PF09827 CRISPR associated protein Cas2 1 67 5.7E-21 T 23-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 A3L04_02055 24edf58b95c5f666d88d2ecd94f7a159 274 Gene3D G3DSA:3.40.50.620 2 186 2.7E-30 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_02055 24edf58b95c5f666d88d2ecd94f7a159 274 Pfam PF06508 Queuosine biosynthesis protein QueC 54 136 1.3E-8 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L04_02055 24edf58b95c5f666d88d2ecd94f7a159 274 PIRSF PIRSF036668 1 273 1.9E-135 T 23-10-2018 IPR012121 ATPase, PP-loop, MJ1599-related A3L04_02055 24edf58b95c5f666d88d2ecd94f7a159 274 SUPERFAMILY SSF52402 25 203 1.81E-31 T 23-10-2018 A3L04_09185 881d24d97582b888e9ce379744231bd6 164 Hamap MF_00647 Phosphopantetheine adenylyltransferase [coaD]. 5 155 33.918 T 23-10-2018 IPR023540 Phosphopantetheine adenylyltransferase, archaea GO:0004595 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A3L04_09185 881d24d97582b888e9ce379744231bd6 164 Gene3D G3DSA:3.40.50.620 5 153 1.9E-41 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_09185 881d24d97582b888e9ce379744231bd6 164 SUPERFAMILY SSF52374 5 144 3.38E-20 T 23-10-2018 A3L04_09185 881d24d97582b888e9ce379744231bd6 164 Pfam PF01467 Cytidylyltransferase-like 8 144 2.0E-17 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L04_09185 881d24d97582b888e9ce379744231bd6 164 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 7 61 1.8E-13 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L04_05600 5d32cdd86a6b31105ea1e930a615ff99 423 Gene3D G3DSA:3.40.50.300 16 103 1.5E-5 T 23-10-2018 A3L04_05600 5d32cdd86a6b31105ea1e930a615ff99 423 Pfam PF13635 Domain of unknown function (DUF4143) 219 371 1.7E-19 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 A3L04_05600 5d32cdd86a6b31105ea1e930a615ff99 423 Pfam PF13173 AAA domain 45 165 5.2E-30 T 23-10-2018 A3L04_05600 5d32cdd86a6b31105ea1e930a615ff99 423 SUPERFAMILY SSF52540 23 221 4.73E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09945 4e7a87b13463bb871e08510e6f1ff55b 87 Pfam PF01169 Uncharacterized protein family UPF0016 6 79 1.1E-24 T 23-10-2018 IPR001727 Gdt1 family A3L04_09845 23540706d274b89f885767ec4d6447ba 180 Gene3D G3DSA:3.40.50.300 1 170 3.9E-42 T 23-10-2018 A3L04_09845 23540706d274b89f885767ec4d6447ba 180 SMART SM00382 2 152 3.7E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_09845 23540706d274b89f885767ec4d6447ba 180 SUPERFAMILY SSF52540 3 158 1.9E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09845 23540706d274b89f885767ec4d6447ba 180 Pfam PF03266 NTPase 2 162 1.8E-55 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A3L04_09845 23540706d274b89f885767ec4d6447ba 180 Hamap MF_00796 Nucleoside-triphosphatase . 1 169 30.051 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A3L04_03630 77a531bba9c68b57d9efe88a7e7b9444 455 Pfam PF09339 IclR helix-turn-helix domain 241 281 8.3E-6 T 23-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A3L04_03630 77a531bba9c68b57d9efe88a7e7b9444 455 SUPERFAMILY SSF52540 3 238 3.42E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_03630 77a531bba9c68b57d9efe88a7e7b9444 455 SUPERFAMILY SSF46785 240 394 2.72E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_03630 77a531bba9c68b57d9efe88a7e7b9444 455 Gene3D G3DSA:3.40.50.300 2 169 9.8E-30 T 23-10-2018 A3L04_03630 77a531bba9c68b57d9efe88a7e7b9444 455 Pfam PF01637 ATPase domain predominantly from Archaea 5 202 1.2E-27 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_03630 77a531bba9c68b57d9efe88a7e7b9444 455 Pfam PF03008 Archaea bacterial proteins of unknown function 306 403 1.4E-30 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L04_03630 77a531bba9c68b57d9efe88a7e7b9444 455 Gene3D G3DSA:1.10.10.10 234 319 2.4E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_08550 bdb9ce2b8f60cea6568ae5df36912db7 380 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 210 8.6E-14 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L04_08550 bdb9ce2b8f60cea6568ae5df36912db7 380 Gene3D G3DSA:3.60.21.10 1 246 1.8E-57 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L04_08550 bdb9ce2b8f60cea6568ae5df36912db7 380 SUPERFAMILY SSF56300 1 304 2.76E-50 T 23-10-2018 A3L04_08550 bdb9ce2b8f60cea6568ae5df36912db7 380 Hamap MF_02044 DNA double-strand break repair protein Mre11 [mre11]. 1 363 24.045 T 23-10-2018 IPR032885 DNA double-strand break repair protein Mre11, archaea-type GO:0006302 A3L04_02580 b2d9810940adcbc3e5be8f5c4d1ec4cb 827 Pfam PF00330 Aconitase family (aconitate hydratase) 47 520 1.6E-160 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A3L04_02580 b2d9810940adcbc3e5be8f5c4d1ec4cb 827 SUPERFAMILY SSF52016 587 824 5.1E-70 T 23-10-2018 A3L04_02580 b2d9810940adcbc3e5be8f5c4d1ec4cb 827 Gene3D G3DSA:3.30.499.20 2 344 1.0E-141 T 23-10-2018 A3L04_02580 b2d9810940adcbc3e5be8f5c4d1ec4cb 827 Gene3D G3DSA:1.10.1440.20 549 605 1.5E-14 T 23-10-2018 A3L04_02580 b2d9810940adcbc3e5be8f5c4d1ec4cb 827 Pfam PF00694 Aconitase C-terminal domain 669 756 3.9E-35 T 23-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 A3L04_02580 b2d9810940adcbc3e5be8f5c4d1ec4cb 827 Gene3D G3DSA:3.30.499.10 345 548 4.0E-80 T 23-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 A3L04_02580 b2d9810940adcbc3e5be8f5c4d1ec4cb 827 PRINTS PR00415 Aconitase family signature 126 139 4.8E-32 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A3L04_02580 b2d9810940adcbc3e5be8f5c4d1ec4cb 827 PRINTS PR00415 Aconitase family signature 268 281 4.8E-32 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A3L04_02580 b2d9810940adcbc3e5be8f5c4d1ec4cb 827 PRINTS PR00415 Aconitase family signature 193 208 4.8E-32 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A3L04_02580 b2d9810940adcbc3e5be8f5c4d1ec4cb 827 PRINTS PR00415 Aconitase family signature 179 192 4.8E-32 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A3L04_02580 b2d9810940adcbc3e5be8f5c4d1ec4cb 827 PRINTS PR00415 Aconitase family signature 344 358 4.8E-32 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A3L04_02580 b2d9810940adcbc3e5be8f5c4d1ec4cb 827 PRINTS PR00415 Aconitase family signature 452 465 4.8E-32 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A3L04_02580 b2d9810940adcbc3e5be8f5c4d1ec4cb 827 PRINTS PR00415 Aconitase family signature 150 158 4.8E-32 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A3L04_02580 b2d9810940adcbc3e5be8f5c4d1ec4cb 827 PRINTS PR00415 Aconitase family signature 390 401 4.8E-32 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A3L04_02580 b2d9810940adcbc3e5be8f5c4d1ec4cb 827 Gene3D G3DSA:3.20.19.10 606 825 3.0E-86 T 23-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 A3L04_02580 b2d9810940adcbc3e5be8f5c4d1ec4cb 827 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 9 824 0.0 T 23-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 A3L04_02580 b2d9810940adcbc3e5be8f5c4d1ec4cb 827 SUPERFAMILY SSF53732 18 574 9.55E-191 T 23-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 A3L04_10130 326eb77996ef108438ebc7d27d6f1e84 246 Pfam PF13649 Methyltransferase domain 45 135 2.1E-21 T 23-10-2018 A3L04_10130 326eb77996ef108438ebc7d27d6f1e84 246 SUPERFAMILY SSF53335 1 236 1.94E-41 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_10130 326eb77996ef108438ebc7d27d6f1e84 246 Gene3D G3DSA:2.20.25.110 147 205 6.3E-27 T 23-10-2018 A3L04_10130 326eb77996ef108438ebc7d27d6f1e84 246 Gene3D G3DSA:3.40.50.150 1 146 1.2E-43 T 23-10-2018 A3L04_08390 89228cc2f79059497c6439bbe0fd60c5 409 Gene3D G3DSA:3.40.50.1260 189 390 1.9E-146 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_08390 89228cc2f79059497c6439bbe0fd60c5 409 PIRSF PIRSF000724 1 407 1.8E-133 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_08390 89228cc2f79059497c6439bbe0fd60c5 409 PRINTS PR00477 Phosphoglycerate kinase family signature 354 365 4.0E-67 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_08390 89228cc2f79059497c6439bbe0fd60c5 409 PRINTS PR00477 Phosphoglycerate kinase family signature 8 24 4.0E-67 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_08390 89228cc2f79059497c6439bbe0fd60c5 409 PRINTS PR00477 Phosphoglycerate kinase family signature 105 120 4.0E-67 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_08390 89228cc2f79059497c6439bbe0fd60c5 409 PRINTS PR00477 Phosphoglycerate kinase family signature 140 162 4.0E-67 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_08390 89228cc2f79059497c6439bbe0fd60c5 409 PRINTS PR00477 Phosphoglycerate kinase family signature 29 51 4.0E-67 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_08390 89228cc2f79059497c6439bbe0fd60c5 409 PRINTS PR00477 Phosphoglycerate kinase family signature 376 393 4.0E-67 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_08390 89228cc2f79059497c6439bbe0fd60c5 409 PRINTS PR00477 Phosphoglycerate kinase family signature 193 212 4.0E-67 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_08390 89228cc2f79059497c6439bbe0fd60c5 409 PRINTS PR00477 Phosphoglycerate kinase family signature 170 192 4.0E-67 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_08390 89228cc2f79059497c6439bbe0fd60c5 409 PRINTS PR00477 Phosphoglycerate kinase family signature 321 346 4.0E-67 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_08390 89228cc2f79059497c6439bbe0fd60c5 409 Pfam PF00162 Phosphoglycerate kinase 5 389 8.9E-113 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_08390 89228cc2f79059497c6439bbe0fd60c5 409 Gene3D G3DSA:3.40.50.1260 8 397 1.9E-146 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_08390 89228cc2f79059497c6439bbe0fd60c5 409 SUPERFAMILY SSF53748 2 399 5.77E-120 T 23-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_08390 89228cc2f79059497c6439bbe0fd60c5 409 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 3 400 35.505 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_04660 5690931dfa7a514d182181bc5953a934 284 PIRSF PIRSF006593 1 284 3.5E-108 T 23-10-2018 IPR014444 Uncharacterised conserved protein UCP006593 A3L04_04660 5690931dfa7a514d182181bc5953a934 284 Gene3D G3DSA:1.10.8.380 1 68 1.3E-32 T 23-10-2018 A3L04_04660 5690931dfa7a514d182181bc5953a934 284 Gene3D G3DSA:3.40.50.10880 134 284 6.9E-59 T 23-10-2018 A3L04_04660 5690931dfa7a514d182181bc5953a934 284 SUPERFAMILY SSF111321 1 282 1.83E-84 T 23-10-2018 IPR036075 AF1104-like superfamily A3L04_04660 5690931dfa7a514d182181bc5953a934 284 Pfam PF01937 Protein of unknown function DUF89 4 277 2.9E-55 T 23-10-2018 IPR002791 Domain of unknown function DUF89 A3L04_04660 5690931dfa7a514d182181bc5953a934 284 Gene3D G3DSA:1.10.285.20 69 133 7.3E-22 T 23-10-2018 A3L04_05030 bf6bd9943a7d74f14486c45cd3770069 185 SMART SM00506 1 143 1.1E-49 T 23-10-2018 IPR002589 Macro domain A3L04_05030 bf6bd9943a7d74f14486c45cd3770069 185 Gene3D G3DSA:3.40.220.10 1 184 2.9E-56 T 23-10-2018 A3L04_05030 bf6bd9943a7d74f14486c45cd3770069 185 SUPERFAMILY SSF52949 2 179 3.2E-51 T 23-10-2018 A3L04_05030 bf6bd9943a7d74f14486c45cd3770069 185 Pfam PF01661 Macro domain 17 142 4.9E-33 T 23-10-2018 IPR002589 Macro domain A3L04_00845 6d167dbf3d42f548a74f7a95b1b67806 91 Gene3D G3DSA:1.10.287.1080 1 91 2.9E-25 T 23-10-2018 A3L04_00845 6d167dbf3d42f548a74f7a95b1b67806 91 SUPERFAMILY SSF101386 2 89 2.62E-21 T 23-10-2018 A3L04_00845 6d167dbf3d42f548a74f7a95b1b67806 91 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 19 90 2.9E-16 T 23-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A3L04_00845 6d167dbf3d42f548a74f7a95b1b67806 91 PIRSF PIRSF029904 1 91 2.9E-32 T 23-10-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD A3L04_00120 6aaffac8aaa192c6419dfc058a3689a6 202 Gene3D G3DSA:3.20.20.140 1 201 1.7E-71 T 23-10-2018 A3L04_00120 6aaffac8aaa192c6419dfc058a3689a6 202 ProDom PD016938 P COMPONENT RIBONUCLEASE RNASE HYDROLASE PROCESSING TRNA SUBUNIT SIMILAR P/RNASE 98 196 3.0E-39 T 23-10-2018 A3L04_00120 6aaffac8aaa192c6419dfc058a3689a6 202 SUPERFAMILY SSF89550 3 199 2.2E-33 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L04_00120 6aaffac8aaa192c6419dfc058a3689a6 202 Hamap MF_00756 Ribonuclease P protein component 3 [rnp3]. 9 202 20.235 T 23-10-2018 IPR023539 Ribonuclease P, protein component 3, archaeal GO:0001682|GO:0004526 A3L04_00120 6aaffac8aaa192c6419dfc058a3689a6 202 Pfam PF01876 RNase P subunit p30 40 192 5.6E-28 T 23-10-2018 IPR002738 RNase P subunit p30 GO:0004540|GO:0008033 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L04_02270 50203a50ec5c3d62d9249d3e50394d55 185 Pfam PF12840 Helix-turn-helix domain 14 68 6.3E-17 T 23-10-2018 A3L04_02270 50203a50ec5c3d62d9249d3e50394d55 185 SUPERFAMILY SSF46785 4 124 2.82E-26 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_02270 50203a50ec5c3d62d9249d3e50394d55 185 SMART SM00418 13 102 4.5E-13 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_02270 50203a50ec5c3d62d9249d3e50394d55 185 Gene3D G3DSA:1.10.10.10 2 87 5.2E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_02270 50203a50ec5c3d62d9249d3e50394d55 185 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 4.0E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_02270 50203a50ec5c3d62d9249d3e50394d55 185 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 4.0E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_01345 43ea3467bc9a60f09888001624d1130f 247 SMART SM00382 22 198 0.0087 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_01345 43ea3467bc9a60f09888001624d1130f 247 Hamap MF_01076 UPF0273 protein . 2 243 65.172 T 23-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like A3L04_01345 43ea3467bc9a60f09888001624d1130f 247 SUPERFAMILY SSF52540 3 236 3.79E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01345 43ea3467bc9a60f09888001624d1130f 247 PRINTS PR01874 DNA repair protein radA signature 14 42 3.6E-9 T 23-10-2018 A3L04_01345 43ea3467bc9a60f09888001624d1130f 247 PRINTS PR01874 DNA repair protein radA signature 56 73 3.6E-9 T 23-10-2018 A3L04_01345 43ea3467bc9a60f09888001624d1130f 247 PRINTS PR01874 DNA repair protein radA signature 135 159 3.6E-9 T 23-10-2018 A3L04_01345 43ea3467bc9a60f09888001624d1130f 247 Gene3D G3DSA:3.40.50.300 1 247 1.2E-83 T 23-10-2018 A3L04_01345 43ea3467bc9a60f09888001624d1130f 247 Pfam PF06745 KaiC 5 237 8.8E-94 T 23-10-2018 IPR014774 KaiC-like domain A3L04_01345 43ea3467bc9a60f09888001624d1130f 247 TIGRFAM TIGR03877 thermo_KaiC_1: KaiC domain protein, Ph0284 family 3 239 1.6E-143 T 23-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like A3L04_09485 08f24cac5f362cb7bf8510964cc92635 178 SUPERFAMILY SSF55729 14 167 4.15E-24 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L04_09485 08f24cac5f362cb7bf8510964cc92635 178 Gene3D G3DSA:3.40.630.30 1 142 2.3E-56 T 23-10-2018 A3L04_09485 08f24cac5f362cb7bf8510964cc92635 178 Pfam PF00583 Acetyltransferase (GNAT) family 35 158 4.3E-17 T 23-10-2018 IPR000182 GNAT domain A3L04_09485 08f24cac5f362cb7bf8510964cc92635 178 Gene3D G3DSA:3.30.1990.20 143 178 6.3E-12 T 23-10-2018 A3L04_07040 8461e1f957da265774b2f81f7cc9a4a5 382 SUPERFAMILY SSF54373 220 312 2.49E-10 T 23-10-2018 A3L04_07040 8461e1f957da265774b2f81f7cc9a4a5 382 Gene3D G3DSA:3.30.9.10 84 311 1.1E-143 T 23-10-2018 A3L04_07040 8461e1f957da265774b2f81f7cc9a4a5 382 Pfam PF01266 FAD dependent oxidoreductase 8 351 6.7E-75 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A3L04_07040 8461e1f957da265774b2f81f7cc9a4a5 382 Gene3D G3DSA:3.50.50.60 8 356 1.1E-143 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_07040 8461e1f957da265774b2f81f7cc9a4a5 382 SUPERFAMILY SSF51905 6 374 1.42E-60 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_07485 75b6f2089bc21c651fbefe2033b71cfb 128 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 109 1.7E-26 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L04_07485 75b6f2089bc21c651fbefe2033b71cfb 128 Pfam PF03334 Na+/H+ antiporter subunit 11 94 2.0E-23 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L04_08080 8967eddbe3b7115f4191c845a4a9d7b4 486 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 306 318 7.3E-10 T 23-10-2018 A3L04_08080 8967eddbe3b7115f4191c845a4a9d7b4 486 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 74 99 7.3E-10 T 23-10-2018 A3L04_08080 8967eddbe3b7115f4191c845a4a9d7b4 486 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 212 233 7.3E-10 T 23-10-2018 A3L04_08080 8967eddbe3b7115f4191c845a4a9d7b4 486 Pfam PF00361 Proton-conducting membrane transporter 124 416 3.6E-59 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_09730 5cc6099e299670d0f14d0db92fbdcc1e 140 TIGRFAM TIGR00311 aIF-2beta: putative translation initiation factor aIF-2, beta subunit 7 139 3.0E-53 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 A3L04_09730 5cc6099e299670d0f14d0db92fbdcc1e 140 Gene3D G3DSA:3.30.70.3150 38 128 2.5E-35 T 23-10-2018 A3L04_09730 5cc6099e299670d0f14d0db92fbdcc1e 140 SUPERFAMILY SSF75689 104 139 2.88E-12 T 23-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L04_09730 5cc6099e299670d0f14d0db92fbdcc1e 140 SUPERFAMILY SSF100966 6 107 9.29E-31 T 23-10-2018 IPR016189 Translation initiation factor IF2/IF5, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L04_09730 5cc6099e299670d0f14d0db92fbdcc1e 140 SMART SM00653 27 134 3.5E-62 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L04_09730 5cc6099e299670d0f14d0db92fbdcc1e 140 Pfam PF01873 Domain found in IF2B/IF5 21 133 2.8E-39 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L04_09730 5cc6099e299670d0f14d0db92fbdcc1e 140 Hamap MF_00232 Translation initiation factor 2 subunit beta [eif2b]. 6 140 34.935 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 A3L04_05865 6d668b47652014a156e0a0264a1c59b1 395 SUPERFAMILY SSF52518 5 251 1.51E-69 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L04_05865 6d668b47652014a156e0a0264a1c59b1 395 Gene3D G3DSA:3.40.50.920 253 392 1.7E-38 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L04_05865 6d668b47652014a156e0a0264a1c59b1 395 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 240 1.1E-79 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L04_05865 6d668b47652014a156e0a0264a1c59b1 395 Gene3D G3DSA:3.40.50.970 3 252 2.1E-105 T 23-10-2018 A3L04_05865 6d668b47652014a156e0a0264a1c59b1 395 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 262 364 2.3E-27 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A3L04_05865 6d668b47652014a156e0a0264a1c59b1 395 SUPERFAMILY SSF52922 254 371 3.85E-30 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L04_06530 a01c858724a417dfe11ee57618ab9550 469 Pfam PF02436 Conserved carboxylase domain 290 448 1.6E-44 T 23-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 A3L04_06530 a01c858724a417dfe11ee57618ab9550 469 Gene3D G3DSA:3.20.20.70 1 450 1.7E-158 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_06530 a01c858724a417dfe11ee57618ab9550 469 Pfam PF00682 HMGL-like 2 266 3.3E-40 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A3L04_06530 a01c858724a417dfe11ee57618ab9550 469 SUPERFAMILY SSF89000 295 438 1.37E-43 T 23-10-2018 A3L04_06530 a01c858724a417dfe11ee57618ab9550 469 SUPERFAMILY SSF51569 2 298 2.38E-84 T 23-10-2018 A3L04_00010 4287e3cdd6c826832eec0e079ccf2bb7 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 322 8.9E-43 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L04_00010 4287e3cdd6c826832eec0e079ccf2bb7 329 Gene3D G3DSA:1.10.3720.10 87 325 1.1E-10 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_00010 4287e3cdd6c826832eec0e079ccf2bb7 329 SUPERFAMILY SSF161098 99 310 1.96E-8 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_03425 a75af3704aee15418c7bc09829f74a85 113 ProSitePatterns PS00056 Ribosomal protein S17 signature. 83 95 - T 23-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03425 a75af3704aee15418c7bc09829f74a85 113 SUPERFAMILY SSF50249 30 109 2.18E-28 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_03425 a75af3704aee15418c7bc09829f74a85 113 TIGRFAM TIGR03630 uS17_arch: ribosomal protein uS17 5 105 4.9E-49 T 23-10-2018 IPR028333 Ribosomal protein S17, archaeal/eukaryotic Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03425 a75af3704aee15418c7bc09829f74a85 113 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 32 103 1.0E-35 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_03425 a75af3704aee15418c7bc09829f74a85 113 Gene3D G3DSA:2.40.50.1000 1 113 2.1E-40 T 23-10-2018 A3L04_03425 a75af3704aee15418c7bc09829f74a85 113 PRINTS PR00973 Ribosomal protein S17 family signature 50 73 5.6E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_03425 a75af3704aee15418c7bc09829f74a85 113 PRINTS PR00973 Ribosomal protein S17 family signature 93 100 5.6E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_03425 a75af3704aee15418c7bc09829f74a85 113 PRINTS PR00973 Ribosomal protein S17 family signature 83 93 5.6E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_03425 a75af3704aee15418c7bc09829f74a85 113 Hamap MF_01345_A 30S ribosomal protein S17 [rpsQ]. 3 107 34.17 T 23-10-2018 IPR019978 Ribosomal protein S17, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_03425 a75af3704aee15418c7bc09829f74a85 113 Pfam PF00366 Ribosomal protein S17 36 103 2.6E-27 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_00935 b4f99af894b6186118b2d0c74ced346d 235 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 13 233 3.1E-52 T 23-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A3L04_00935 b4f99af894b6186118b2d0c74ced346d 235 Pfam PF02237 Biotin protein ligase C terminal domain 188 233 1.0E-12 T 23-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A3L04_00935 b4f99af894b6186118b2d0c74ced346d 235 Pfam PF03099 Biotin/lipoate A/B protein ligase family 19 133 6.0E-20 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A3L04_00935 b4f99af894b6186118b2d0c74ced346d 235 SUPERFAMILY SSF55681 3 174 1.08E-50 T 23-10-2018 A3L04_00935 b4f99af894b6186118b2d0c74ced346d 235 Gene3D G3DSA:2.30.30.100 188 235 7.4E-18 T 23-10-2018 A3L04_00935 b4f99af894b6186118b2d0c74ced346d 235 SUPERFAMILY SSF50037 191 233 5.04E-10 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal A3L04_00935 b4f99af894b6186118b2d0c74ced346d 235 Gene3D G3DSA:3.30.930.10 1 187 2.1E-63 T 23-10-2018 A3L04_08840 addbdf53e727ed55cb0d0ef38cec0f5f 476 SUPERFAMILY SSF51338 4 474 2.16E-9 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L04_08840 addbdf53e727ed55cb0d0ef38cec0f5f 476 Gene3D G3DSA:2.30.40.10 5 473 2.6E-170 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L04_08840 addbdf53e727ed55cb0d0ef38cec0f5f 476 Gene3D G3DSA:3.10.310.70 78 179 2.6E-170 T 23-10-2018 A3L04_08840 addbdf53e727ed55cb0d0ef38cec0f5f 476 Pfam PF07969 Amidohydrolase family 49 475 3.0E-90 T 23-10-2018 IPR013108 Amidohydrolase 3 A3L04_08840 addbdf53e727ed55cb0d0ef38cec0f5f 476 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 61 69 - T 23-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A3L04_08840 addbdf53e727ed55cb0d0ef38cec0f5f 476 SUPERFAMILY SSF51556 59 448 1.17E-28 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L04_08840 addbdf53e727ed55cb0d0ef38cec0f5f 476 Gene3D G3DSA:3.20.20.140 60 455 2.6E-170 T 23-10-2018 A3L04_02535 a7033f8f7f64703207ed59953c9f7345 485 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 14 452 6.4E-196 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A3L04_02535 a7033f8f7f64703207ed59953c9f7345 485 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 14 483 83.069 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A3L04_02535 a7033f8f7f64703207ed59953c9f7345 485 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 291 303 - T 23-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 A3L04_02535 a7033f8f7f64703207ed59953c9f7345 485 SMART SM01240 13 470 7.6E-265 T 23-10-2018 A3L04_02535 a7033f8f7f64703207ed59953c9f7345 485 SMART SM00116 102 149 6.9E-15 T 23-10-2018 IPR000644 CBS domain A3L04_02535 a7033f8f7f64703207ed59953c9f7345 485 SMART SM00116 159 207 1.2E-14 T 23-10-2018 IPR000644 CBS domain A3L04_02535 a7033f8f7f64703207ed59953c9f7345 485 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 14 470 3.1E-148 T 23-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A3L04_02535 a7033f8f7f64703207ed59953c9f7345 485 SUPERFAMILY SSF54631 94 203 2.91E-34 T 23-10-2018 A3L04_02535 a7033f8f7f64703207ed59953c9f7345 485 Gene3D G3DSA:3.20.20.70 6 483 8.6E-200 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_02535 a7033f8f7f64703207ed59953c9f7345 485 Pfam PF00571 CBS domain 100 145 2.5E-13 T 23-10-2018 IPR000644 CBS domain A3L04_02535 a7033f8f7f64703207ed59953c9f7345 485 Pfam PF00571 CBS domain 152 204 1.0E-16 T 23-10-2018 IPR000644 CBS domain A3L04_02535 a7033f8f7f64703207ed59953c9f7345 485 PIRSF PIRSF000130 3 485 3.9E-198 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A3L04_02535 a7033f8f7f64703207ed59953c9f7345 485 SUPERFAMILY SSF51412 11 474 1.22E-109 T 23-10-2018 A3L04_08865 d2ec09327258c6904800b4445e36d5fb 438 Pfam PF01336 OB-fold nucleic acid binding domain 19 98 6.8E-13 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L04_08865 d2ec09327258c6904800b4445e36d5fb 438 SUPERFAMILY SSF55681 96 437 1.21E-101 T 23-10-2018 A3L04_08865 d2ec09327258c6904800b4445e36d5fb 438 SUPERFAMILY SSF50249 1 101 3.24E-26 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_08865 d2ec09327258c6904800b4445e36d5fb 438 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 5 438 6.0E-188 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L04_08865 d2ec09327258c6904800b4445e36d5fb 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 393 407 7.8E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_08865 d2ec09327258c6904800b4445e36d5fb 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 204 217 7.8E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_08865 d2ec09327258c6904800b4445e36d5fb 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 353 369 7.8E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_08865 d2ec09327258c6904800b4445e36d5fb 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 187 199 7.8E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_08865 d2ec09327258c6904800b4445e36d5fb 438 Gene3D G3DSA:3.30.930.10 108 438 3.5E-123 T 23-10-2018 A3L04_08865 d2ec09327258c6904800b4445e36d5fb 438 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 2 438 43.974 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L04_08865 d2ec09327258c6904800b4445e36d5fb 438 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 432 1.6E-95 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_08865 d2ec09327258c6904800b4445e36d5fb 438 Gene3D G3DSA:2.40.50.140 1 107 5.4E-27 T 23-10-2018 A3L04_04005 46a7b1dd92b9ad5ac81bdb526ef4264a 61 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 60 7.6E-18 T 23-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain A3L04_04005 46a7b1dd92b9ad5ac81bdb526ef4264a 61 Gene3D G3DSA:1.10.20.10 1 60 9.5E-20 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L04_04005 46a7b1dd92b9ad5ac81bdb526ef4264a 61 SUPERFAMILY SSF47113 3 60 4.94E-16 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L04_02475 1fa783a5f8a6593273e9f1c716ef68fb 641 SUPERFAMILY SSF88713 2 307 2.59E-68 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L04_02475 1fa783a5f8a6593273e9f1c716ef68fb 641 Pfam PF09095 Domain of unknown function (DUF1926) 390 637 1.1E-58 T 23-10-2018 IPR015179 Alpha-amylase/4-alpha-glucanotransferase, C-terminal GO:0003824|GO:0005975|GO:0030246 A3L04_02475 1fa783a5f8a6593273e9f1c716ef68fb 641 Gene3D G3DSA:3.20.110.20 1 379 1.8E-176 T 23-10-2018 A3L04_02475 1fa783a5f8a6593273e9f1c716ef68fb 641 ProDom PD014405 HYDROLASE METABOLISM CARBOHYDRATE GLYCOSIDASE ALPHA-AMYLASE TRANSFERASE 4-ALPHA-GLUCANOTRANSFERASE GLYCOSYLTRANSFERASE FAMILY DIRECT 317 382 1.0E-29 T 23-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain A3L04_02475 1fa783a5f8a6593273e9f1c716ef68fb 641 SUPERFAMILY SSF74650 386 640 2.32E-80 T 23-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 A3L04_02475 1fa783a5f8a6593273e9f1c716ef68fb 641 Gene3D G3DSA:2.70.98.10 386 641 1.3E-63 T 23-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A3L04_02475 1fa783a5f8a6593273e9f1c716ef68fb 641 Pfam PF09094 Domain of unknown function (DUF1925) 309 381 2.7E-37 T 23-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain A3L04_02475 1fa783a5f8a6593273e9f1c716ef68fb 641 Pfam PF03065 Glycosyl hydrolase family 57 5 288 2.6E-63 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A3L04_02475 1fa783a5f8a6593273e9f1c716ef68fb 641 SUPERFAMILY SSF88688 309 381 1.7E-37 T 23-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily A3L04_03180 b730ec86ab2f49c1d0c520ee24ef2e4d 284 SUPERFAMILY SSF53686 3 265 2.62E-60 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L04_03180 b730ec86ab2f49c1d0c520ee24ef2e4d 284 Gene3D G3DSA:3.40.50.1100 3 260 6.1E-70 T 23-10-2018 A3L04_03180 b730ec86ab2f49c1d0c520ee24ef2e4d 284 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 3 254 1.0E-45 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L04_03180 b730ec86ab2f49c1d0c520ee24ef2e4d 284 Gene3D G3DSA:3.40.50.1100 19 120 6.1E-70 T 23-10-2018 A3L04_03380 ad9ed76a3dc72a195ca8edcc70eb2351 255 SUPERFAMILY SSF52166 1 252 8.11E-72 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 A3L04_03380 ad9ed76a3dc72a195ca8edcc70eb2351 255 TIGRFAM TIGR03672 rpl4p_arch: 50S ribosomal protein uL4 1 252 8.5E-117 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 A3L04_03380 ad9ed76a3dc72a195ca8edcc70eb2351 255 ProSitePatterns PS00939 Ribosomal protein L1e signature. 106 132 - T 23-10-2018 IPR013000 Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03380 ad9ed76a3dc72a195ca8edcc70eb2351 255 Pfam PF00573 Ribosomal protein L4/L1 family 16 252 1.8E-49 T 23-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 A3L04_03380 ad9ed76a3dc72a195ca8edcc70eb2351 255 Hamap MF_01328_A 50S ribosomal protein L4 [rplD]. 2 253 44.456 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 A3L04_03380 ad9ed76a3dc72a195ca8edcc70eb2351 255 Gene3D G3DSA:3.40.1370.10 1 255 4.0E-96 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 A3L04_05005 475feea991a9cfdf81d6477e384a0a15 62 ProDom PD005132 RIBOSOMAL RRNA-BINDING METAL-BINDING RNA-BINDING ZINC RIBONUCLEOPROTEIN ZINC-FINGER L37 60S L37E 9 41 5.0E-12 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_05005 475feea991a9cfdf81d6477e384a0a15 62 Gene3D G3DSA:2.20.25.30 1 59 1.2E-21 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_05005 475feea991a9cfdf81d6477e384a0a15 62 SUPERFAMILY SSF57829 1 56 3.3E-20 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L04_05005 475feea991a9cfdf81d6477e384a0a15 62 Pfam PF01907 Ribosomal protein L37e 3 56 5.4E-22 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_05005 475feea991a9cfdf81d6477e384a0a15 62 ProSitePatterns PS01077 Ribosomal protein L37e signature. 4 24 - T 23-10-2018 IPR018267 Ribosomal protein L37e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_05005 475feea991a9cfdf81d6477e384a0a15 62 Hamap MF_00547 50S ribosomal protein L37e [rpl37e]. 2 55 20.994 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_00400 d7666e7aab81bde9218dc84849a2bf23 164 Gene3D G3DSA:1.10.10.250 73 163 9.2E-38 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily A3L04_00400 d7666e7aab81bde9218dc84849a2bf23 164 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 2 139 28.461 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A3L04_00400 d7666e7aab81bde9218dc84849a2bf23 164 SUPERFAMILY SSF54747 4 82 3.4E-25 T 23-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily A3L04_00400 d7666e7aab81bde9218dc84849a2bf23 164 Pfam PF03946 Ribosomal protein L11, N-terminal domain 6 59 1.5E-22 T 23-10-2018 IPR020784 Ribosomal protein L11, N-terminal A3L04_00400 d7666e7aab81bde9218dc84849a2bf23 164 Gene3D G3DSA:2.10.260.30 3 69 5.6E-28 T 23-10-2018 A3L04_00400 d7666e7aab81bde9218dc84849a2bf23 164 Pfam PF00298 Ribosomal protein L11, RNA binding domain 70 137 3.9E-25 T 23-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A3L04_00400 d7666e7aab81bde9218dc84849a2bf23 164 SMART SM00649 6 138 1.9E-70 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A3L04_00400 d7666e7aab81bde9218dc84849a2bf23 164 SUPERFAMILY SSF46906 66 138 2.62E-24 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily A3L04_00400 d7666e7aab81bde9218dc84849a2bf23 164 ProSitePatterns PS00359 Ribosomal protein L11 signature. 124 139 - T 23-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_04060 9250b86d11503d2e98fc9f57590a176f 237 SUPERFAMILY SSF53271 75 236 1.21E-31 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L04_04060 9250b86d11503d2e98fc9f57590a176f 237 Pfam PF00156 Phosphoribosyl transferase domain 114 215 6.7E-11 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L04_04060 9250b86d11503d2e98fc9f57590a176f 237 SUPERFAMILY SSF47413 11 62 7.51E-6 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L04_04060 9250b86d11503d2e98fc9f57590a176f 237 Gene3D G3DSA:3.40.50.2020 59 237 3.2E-38 T 23-10-2018 A3L04_04060 9250b86d11503d2e98fc9f57590a176f 237 Pfam PF01381 Helix-turn-helix 14 62 5.1E-7 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L04_08000 2cb014c9dbb2cfb72161dccec1daed70 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 8.0E-10 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A3L04_08000 2cb014c9dbb2cfb72161dccec1daed70 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 8.0E-10 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A3L04_08000 2cb014c9dbb2cfb72161dccec1daed70 192 Gene3D G3DSA:1.10.357.10 1 188 1.2E-28 T 23-10-2018 A3L04_08000 2cb014c9dbb2cfb72161dccec1daed70 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 1.2E-16 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A3L04_08000 2cb014c9dbb2cfb72161dccec1daed70 192 SUPERFAMILY SSF46689 2 57 9.48E-17 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A3L04_01725 9439ea90537d694ee2cd9c3e415fa4f1 280 Gene3D G3DSA:2.30.140.10 1 53 1.7E-26 T 23-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L04_01725 9439ea90537d694ee2cd9c3e415fa4f1 280 Pfam PF17284 Spermidine synthase tetramerisation domain 3 51 1.2E-13 T 23-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L04_01725 9439ea90537d694ee2cd9c3e415fa4f1 280 Gene3D G3DSA:3.40.50.150 55 280 1.0E-77 T 23-10-2018 A3L04_01725 9439ea90537d694ee2cd9c3e415fa4f1 280 SUPERFAMILY SSF53335 3 278 1.82E-72 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_01725 9439ea90537d694ee2cd9c3e415fa4f1 280 Pfam PF01564 Spermine/spermidine synthase domain 56 239 6.0E-48 T 23-10-2018 A3L04_01725 9439ea90537d694ee2cd9c3e415fa4f1 280 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 1 278 35.802 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L04_01725 9439ea90537d694ee2cd9c3e415fa4f1 280 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 77 90 - T 23-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L04_01725 9439ea90537d694ee2cd9c3e415fa4f1 280 TIGRFAM TIGR00417 speE: spermidine synthase 3 272 3.4E-77 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L04_05085 8e1d2f87a9bb76edfca7235a47851220 405 SUPERFAMILY SSF56281 5 255 3.41E-46 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_05085 8e1d2f87a9bb76edfca7235a47851220 405 Gene3D G3DSA:3.60.15.10 1 258 8.0E-90 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_05085 8e1d2f87a9bb76edfca7235a47851220 405 PIRSF PIRSF005243 5 405 3.3E-114 T 23-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 A3L04_05085 8e1d2f87a9bb76edfca7235a47851220 405 SUPERFAMILY SSF52218 262 404 7.05E-26 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A3L04_05085 8e1d2f87a9bb76edfca7235a47851220 405 Pfam PF00753 Metallo-beta-lactamase superfamily 41 185 5.7E-8 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_05085 8e1d2f87a9bb76edfca7235a47851220 405 Gene3D G3DSA:3.40.50.360 259 403 2.8E-26 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A3L04_05085 8e1d2f87a9bb76edfca7235a47851220 405 SMART SM00849 39 209 6.6E-28 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_00490 be2ff9b7e028ed78d5ad35cfdddec75f 385 SUPERFAMILY SSF52540 39 222 2.19E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_00490 be2ff9b7e028ed78d5ad35cfdddec75f 385 Pfam PF13173 AAA domain 44 175 9.8E-21 T 23-10-2018 A3L04_00490 be2ff9b7e028ed78d5ad35cfdddec75f 385 SUPERFAMILY SSF46785 234 279 2.83E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_00490 be2ff9b7e028ed78d5ad35cfdddec75f 385 Gene3D G3DSA:3.40.50.300 30 132 3.2E-6 T 23-10-2018 A3L04_03285 7993988d15523e4ecd3f5626544d5bd3 218 Gene3D G3DSA:1.10.10.580 147 216 3.1E-36 T 23-10-2018 IPR023093 ScpA-like, C-terminal A3L04_03285 7993988d15523e4ecd3f5626544d5bd3 218 Pfam PF02616 Segregation and condensation protein ScpA 19 160 7.5E-12 T 23-10-2018 IPR003768 Segregation and condensation protein A A3L04_07080 ad6ce1efec9967173d36660d86e08a48 427 Pfam PF00860 Permease family 17 393 3.0E-97 T 23-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A3L04_07080 ad6ce1efec9967173d36660d86e08a48 427 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 341 361 - T 23-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A3L04_07080 ad6ce1efec9967173d36660d86e08a48 427 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 17 423 1.1E-99 T 23-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A3L04_08635 be54f0d51359ac57be260180442a8ca4 773 SUPERFAMILY SSF55821 176 391 6.1E-45 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A3L04_08635 be54f0d51359ac57be260180442a8ca4 773 Pfam PF00814 Glycoprotease family 611 739 9.4E-7 T 23-10-2018 IPR000905 Gcp-like domain A3L04_08635 be54f0d51359ac57be260180442a8ca4 773 Gene3D G3DSA:3.30.420.360 384 756 2.1E-106 T 23-10-2018 A3L04_08635 be54f0d51359ac57be260180442a8ca4 773 SUPERFAMILY SSF54975 1 88 5.01E-26 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L04_08635 be54f0d51359ac57be260180442a8ca4 773 SUPERFAMILY SSF53067 543 738 1.72E-5 T 23-10-2018 A3L04_08635 be54f0d51359ac57be260180442a8ca4 773 Gene3D G3DSA:3.30.420.350 487 744 2.1E-106 T 23-10-2018 A3L04_08635 be54f0d51359ac57be260180442a8ca4 773 PIRSF PIRSF006256 1 766 9.6E-291 T 23-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 A3L04_08635 be54f0d51359ac57be260180442a8ca4 773 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 6 756 9.6E-268 T 23-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 A3L04_08635 be54f0d51359ac57be260180442a8ca4 773 Gene3D G3DSA:3.30.110.120 253 372 1.1E-144 T 23-10-2018 A3L04_08635 be54f0d51359ac57be260180442a8ca4 773 Pfam PF07503 HypF finger 159 192 3.4E-15 T 23-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 A3L04_08635 be54f0d51359ac57be260180442a8ca4 773 Pfam PF07503 HypF finger 109 142 1.7E-16 T 23-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 A3L04_08635 be54f0d51359ac57be260180442a8ca4 773 Pfam PF00708 Acylphosphatase 4 87 2.1E-23 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L04_08635 be54f0d51359ac57be260180442a8ca4 773 Gene3D G3DSA:3.90.870.50 6 363 1.1E-144 T 23-10-2018 A3L04_08635 be54f0d51359ac57be260180442a8ca4 773 Pfam PF01300 Telomere recombination 210 384 9.0E-48 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 A3L04_01995 2e3973db3f0640a7c4d5574989e36d7b 103 SUPERFAMILY SSF81573 36 88 4.51E-5 T 23-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily A3L04_01995 2e3973db3f0640a7c4d5574989e36d7b 103 Pfam PF16999 Vacuolar (H+)-ATPase G subunit 3 98 5.5E-7 T 23-10-2018 A3L04_01995 2e3973db3f0640a7c4d5574989e36d7b 103 TIGRFAM TIGR02926 AhaH: ATP synthase archaeal, H subunit 5 89 9.1E-21 T 23-10-2018 IPR014275 ATPase, A1A0, subunit H A3L04_05345 fe5e167ae31cc805ac74ca2941d6a399 414 Pfam PF13635 Domain of unknown function (DUF4143) 203 353 6.3E-12 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 A3L04_05345 fe5e167ae31cc805ac74ca2941d6a399 414 Pfam PF13173 AAA domain 30 154 6.5E-32 T 23-10-2018 A3L04_05345 fe5e167ae31cc805ac74ca2941d6a399 414 SUPERFAMILY SSF52540 28 223 3.79E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09325 4fedf3a341e289eed9323f6cb50fa3b8 400 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 23 398 9.2E-159 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 A3L04_09325 4fedf3a341e289eed9323f6cb50fa3b8 400 PIRSF PIRSF015658 1 400 1.8E-168 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 A3L04_09325 4fedf3a341e289eed9323f6cb50fa3b8 400 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 22 394 7.0E-157 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 A3L04_07825 8612dfe49e25653973aad18ff2f84af8 268 SUPERFAMILY SSF51658 1 239 3.8E-29 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily A3L04_07825 8612dfe49e25653973aad18ff2f84af8 268 Gene3D G3DSA:3.20.20.150 1 256 1.9E-29 T 23-10-2018 A3L04_07825 8612dfe49e25653973aad18ff2f84af8 268 Pfam PF01261 Xylose isomerase-like TIM barrel 29 228 1.6E-15 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A3L04_02285 d9585caaf1655f4f78e2ad2efa573f3e 420 Gene3D G3DSA:3.90.550.10 1 220 6.0E-53 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_02285 d9585caaf1655f4f78e2ad2efa573f3e 420 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 366 400 5.5E-6 T 23-10-2018 IPR001451 Hexapeptide repeat A3L04_02285 d9585caaf1655f4f78e2ad2efa573f3e 420 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 255 288 1.6E-9 T 23-10-2018 IPR001451 Hexapeptide repeat A3L04_02285 d9585caaf1655f4f78e2ad2efa573f3e 420 TIGRFAM TIGR03992 Arch_glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 1 399 4.2E-156 T 23-10-2018 IPR023915 UDP-GlcNAc diphosphorylase/GlcNAc-1-P N-acetyltransferase, GlmU, archaeal-type GO:0003977|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 A3L04_02285 d9585caaf1655f4f78e2ad2efa573f3e 420 Gene3D G3DSA:2.160.10.10 221 410 1.3E-58 T 23-10-2018 A3L04_02285 d9585caaf1655f4f78e2ad2efa573f3e 420 SUPERFAMILY SSF53448 1 313 7.74E-74 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_02285 d9585caaf1655f4f78e2ad2efa573f3e 420 Pfam PF00483 Nucleotidyl transferase 2 233 1.3E-41 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L04_02285 d9585caaf1655f4f78e2ad2efa573f3e 420 SUPERFAMILY SSF51161 244 410 6.21E-40 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A3L04_04300 8dab5823ccb66fda75e5588bf784c1cb 394 SUPERFAMILY SSF53218 179 319 3.66E-35 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L04_04300 8dab5823ccb66fda75e5588bf784c1cb 394 SUPERFAMILY SSF63882 6 180 1.31E-59 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L04_04300 8dab5823ccb66fda75e5588bf784c1cb 394 Gene3D G3DSA:2.40.340.10 318 394 4.4E-25 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L04_04300 8dab5823ccb66fda75e5588bf784c1cb 394 Gene3D G3DSA:3.40.980.10 21 312 5.7E-113 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L04_04300 8dab5823ccb66fda75e5588bf784c1cb 394 Pfam PF00994 Probable molybdopterin binding domain 184 313 1.5E-18 T 23-10-2018 IPR001453 MoaB/Mog domain A3L04_04300 8dab5823ccb66fda75e5588bf784c1cb 394 Pfam PF03453 MoeA N-terminal region (domain I and II) 8 171 1.7E-47 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L04_04300 8dab5823ccb66fda75e5588bf784c1cb 394 Gene3D G3DSA:3.90.105.10 25 179 5.7E-113 T 23-10-2018 A3L04_04300 8dab5823ccb66fda75e5588bf784c1cb 394 SMART SM00852 184 315 2.0E-30 T 23-10-2018 IPR001453 MoaB/Mog domain A3L04_04300 8dab5823ccb66fda75e5588bf784c1cb 394 Gene3D G3DSA:2.170.190.11 48 146 5.7E-113 T 23-10-2018 A3L04_04300 8dab5823ccb66fda75e5588bf784c1cb 394 SUPERFAMILY SSF63867 325 394 4.19E-18 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L04_04300 8dab5823ccb66fda75e5588bf784c1cb 394 Pfam PF03454 MoeA C-terminal region (domain IV) 327 391 2.7E-14 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L04_07850 fbb3f82162fa3ae981a4e1d5dd1e31c6 356 Pfam PF03463 eRF1 domain 1 7 127 1.9E-28 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A3L04_07850 fbb3f82162fa3ae981a4e1d5dd1e31c6 356 Gene3D G3DSA:3.30.1330.30 258 356 5.7E-31 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L04_07850 fbb3f82162fa3ae981a4e1d5dd1e31c6 356 Gene3D G3DSA:3.30.420.60 133 256 1.9E-35 T 23-10-2018 A3L04_07850 fbb3f82162fa3ae981a4e1d5dd1e31c6 356 SUPERFAMILY SSF159065 3 129 1.27E-35 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain A3L04_07850 fbb3f82162fa3ae981a4e1d5dd1e31c6 356 SUPERFAMILY SSF55315 251 355 3.24E-27 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L04_07850 fbb3f82162fa3ae981a4e1d5dd1e31c6 356 Gene3D G3DSA:2.30.30.870 1 129 5.4E-37 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain A3L04_07850 fbb3f82162fa3ae981a4e1d5dd1e31c6 356 SUPERFAMILY SSF53137 131 259 1.09E-31 T 23-10-2018 A3L04_07850 fbb3f82162fa3ae981a4e1d5dd1e31c6 356 Hamap MF_01853 Protein pelota homolog [pelA]. 2 355 36.681 T 23-10-2018 IPR023521 Translation release factor pelota, archaea GO:0070481|GO:0070966|GO:0071025 A3L04_07850 fbb3f82162fa3ae981a4e1d5dd1e31c6 356 TIGRFAM TIGR00111 pelota: mRNA surveillance protein pelota 2 355 7.9E-109 T 23-10-2018 IPR004405 Translation release factor pelota GO:0070481|GO:0070966|GO:0071025 A3L04_07850 fbb3f82162fa3ae981a4e1d5dd1e31c6 356 SMART SM01194 1 129 7.7E-46 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A3L04_07850 fbb3f82162fa3ae981a4e1d5dd1e31c6 356 Pfam PF03464 eRF1 domain 2 136 248 3.4E-15 T 23-10-2018 IPR005141 eRF1 domain 2 A3L04_07850 fbb3f82162fa3ae981a4e1d5dd1e31c6 356 Pfam PF03465 eRF1 domain 3 261 355 2.1E-24 T 23-10-2018 IPR005142 eRF1 domain 3 A3L04_02090 f6646de2bedceaff15980d60a6a34297 319 SMART SM00382 34 240 1.8E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_02090 f6646de2bedceaff15980d60a6a34297 319 SUPERFAMILY SSF52540 33 314 3.22E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_02090 f6646de2bedceaff15980d60a6a34297 319 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 298 1.9E-21 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L04_02090 f6646de2bedceaff15980d60a6a34297 319 Gene3D G3DSA:3.40.50.300 2 319 8.4E-105 T 23-10-2018 A3L04_02090 f6646de2bedceaff15980d60a6a34297 319 Pfam PF00005 ABC transporter 26 182 1.8E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_02090 f6646de2bedceaff15980d60a6a34297 319 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_02090 f6646de2bedceaff15980d60a6a34297 319 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 2.4E-32 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L04_05220 90951fd1a8afd33c87758385dab0ae75 177 SUPERFAMILY SSF46785 22 70 4.75E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_05220 90951fd1a8afd33c87758385dab0ae75 177 SUPERFAMILY SSF54909 85 157 3.08E-5 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L04_05220 90951fd1a8afd33c87758385dab0ae75 177 SMART SM00344 23 131 1.9E-4 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L04_05220 90951fd1a8afd33c87758385dab0ae75 177 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 50 69 1.1E-7 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_05220 90951fd1a8afd33c87758385dab0ae75 177 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 50 1.1E-7 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_05220 90951fd1a8afd33c87758385dab0ae75 177 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 39 1.1E-7 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_05220 90951fd1a8afd33c87758385dab0ae75 177 Gene3D G3DSA:1.10.10.10 16 74 4.4E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_05220 90951fd1a8afd33c87758385dab0ae75 177 Pfam PF13412 Winged helix-turn-helix DNA-binding 23 70 7.5E-8 T 23-10-2018 A3L04_02990 5bbc0b4447bcb961f4eb6afc0bacc9c1 100 Gene3D G3DSA:3.30.56.30 1 100 5.9E-34 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L04_02990 5bbc0b4447bcb961f4eb6afc0bacc9c1 100 SUPERFAMILY SSF69695 2 99 7.98E-23 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L04_02990 5bbc0b4447bcb961f4eb6afc0bacc9c1 100 Pfam PF01922 SRP19 protein 5 93 7.1E-12 T 23-10-2018 IPR002778 Signal recognition particle, SRP19 subunit GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L04_02990 5bbc0b4447bcb961f4eb6afc0bacc9c1 100 Hamap MF_00305 Signal recognition particle 19 kDa protein [srp19]. 5 94 22.16 T 23-10-2018 IPR022938 Signal recognition particle, SRP19 subunit, archaeal-type A3L04_09985 6c402a3a73ff178a34d3267bbaa7c5b3 264 Pfam PF00005 ABC transporter 17 162 4.2E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_09985 6c402a3a73ff178a34d3267bbaa7c5b3 264 SUPERFAMILY SSF52540 2 220 3.47E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09985 6c402a3a73ff178a34d3267bbaa7c5b3 264 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_09985 6c402a3a73ff178a34d3267bbaa7c5b3 264 SMART SM00382 26 237 1.7E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_09985 6c402a3a73ff178a34d3267bbaa7c5b3 264 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 12 192 1.2E-65 T 23-10-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 A3L04_09985 6c402a3a73ff178a34d3267bbaa7c5b3 264 Gene3D G3DSA:3.40.50.300 1 233 1.4E-69 T 23-10-2018 A3L04_06500 e12df789b1163e17ed2c02ab8c94a799 423 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 188 328 4.2E-15 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L04_06500 e12df789b1163e17ed2c02ab8c94a799 423 Gene3D G3DSA:3.40.50.11060 8 129 2.4E-33 T 23-10-2018 A3L04_06500 e12df789b1163e17ed2c02ab8c94a799 423 Gene3D G3DSA:3.40.50.300 187 361 8.2E-43 T 23-10-2018 A3L04_06500 e12df789b1163e17ed2c02ab8c94a799 423 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 188 208 5.1E-8 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_06500 e12df789b1163e17ed2c02ab8c94a799 423 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 254 272 5.1E-8 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_06500 e12df789b1163e17ed2c02ab8c94a799 423 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 209 227 5.1E-8 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_06500 e12df789b1163e17ed2c02ab8c94a799 423 PIRSF PIRSF006809 1 420 7.4E-124 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 A3L04_06500 e12df789b1163e17ed2c02ab8c94a799 423 Pfam PF13167 GTP-binding GTPase N-terminal 17 100 6.3E-22 T 23-10-2018 IPR025121 GTPase HflX, N-terminal A3L04_06500 e12df789b1163e17ed2c02ab8c94a799 423 Hamap MF_00900 GTPase HflX [hflX]. 17 386 42.401 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 A3L04_06500 e12df789b1163e17ed2c02ab8c94a799 423 SUPERFAMILY SSF52540 188 376 3.83E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_06500 e12df789b1163e17ed2c02ab8c94a799 423 Pfam PF16360 GTP-binding GTPase Middle Region 103 180 3.3E-19 T 23-10-2018 IPR032305 GTP-binding protein, middle domain A3L04_06500 e12df789b1163e17ed2c02ab8c94a799 423 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 8 356 1.5E-94 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 A3L04_06500 e12df789b1163e17ed2c02ab8c94a799 423 Pfam PF01926 50S ribosome-binding GTPase 188 307 8.8E-21 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_05140 897b21a03ca015f51f2cd677a65e4241 151 SUPERFAMILY SSF46785 5 96 2.46E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_05140 897b21a03ca015f51f2cd677a65e4241 151 Pfam PF03551 Transcriptional regulator PadR-like family 14 83 6.1E-18 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L04_05140 897b21a03ca015f51f2cd677a65e4241 151 Gene3D G3DSA:1.10.10.10 2 105 5.3E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_05390 fdc0ffbecd381b26d77564d99592be4f 362 SMART SM00382 31 196 0.0063 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_05390 fdc0ffbecd381b26d77564d99592be4f 362 Gene3D G3DSA:3.40.50.300 1 201 6.5E-33 T 23-10-2018 A3L04_05390 fdc0ffbecd381b26d77564d99592be4f 362 Gene3D G3DSA:1.10.8.60 204 278 3.6E-12 T 23-10-2018 A3L04_05390 fdc0ffbecd381b26d77564d99592be4f 362 SUPERFAMILY SSF52540 2 269 1.13E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_05390 fdc0ffbecd381b26d77564d99592be4f 362 Pfam PF01637 ATPase domain predominantly from Archaea 21 179 4.2E-10 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_00735 c451aabf6f590e12afeb121bd1b164c7 80 SMART SM00966 6 48 1.8E-5 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L04_00735 c451aabf6f590e12afeb121bd1b164c7 80 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 44 1.1E-8 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L04_00735 c451aabf6f590e12afeb121bd1b164c7 80 Gene3D G3DSA:2.10.260.10 1 41 2.8E-5 T 23-10-2018 A3L04_00735 c451aabf6f590e12afeb121bd1b164c7 80 SUPERFAMILY SSF89447 1 51 1.83E-8 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L04_08490 aae884c01843cd4594fe8e2e6ac20f5b 952 Pfam PF13020 Domain of unknown function (DUF3883) 839 928 7.5E-17 T 23-10-2018 IPR024975 Domain of unknown function DUF3883 A3L04_08490 aae884c01843cd4594fe8e2e6ac20f5b 952 Pfam PF00176 SNF2 family N-terminal domain 60 215 3.5E-12 T 23-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 A3L04_08490 aae884c01843cd4594fe8e2e6ac20f5b 952 Gene3D G3DSA:3.40.50.300 331 532 1.5E-36 T 23-10-2018 A3L04_08490 aae884c01843cd4594fe8e2e6ac20f5b 952 SMART SM00490 421 502 2.1E-16 T 23-10-2018 IPR001650 Helicase, C-terminal A3L04_08490 aae884c01843cd4594fe8e2e6ac20f5b 952 Gene3D G3DSA:3.40.50.10810 37 330 5.5E-44 T 23-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily A3L04_08490 aae884c01843cd4594fe8e2e6ac20f5b 952 SUPERFAMILY SSF52540 154 540 2.83E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_08490 aae884c01843cd4594fe8e2e6ac20f5b 952 Pfam PF00271 Helicase conserved C-terminal domain 391 502 8.7E-18 T 23-10-2018 IPR001650 Helicase, C-terminal A3L04_08490 aae884c01843cd4594fe8e2e6ac20f5b 952 SUPERFAMILY SSF52540 13 221 1.19E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_08490 aae884c01843cd4594fe8e2e6ac20f5b 952 SMART SM00487 36 231 3.2E-18 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L04_00690 beed72055f57f4335362af895df7a3ee 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 3.3E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_00690 beed72055f57f4335362af895df7a3ee 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 3.3E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_00690 beed72055f57f4335362af895df7a3ee 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 3.3E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_00690 beed72055f57f4335362af895df7a3ee 155 Gene3D G3DSA:3.30.70.920 55 151 2.2E-13 T 23-10-2018 A3L04_00690 beed72055f57f4335362af895df7a3ee 155 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 23-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A3L04_00690 beed72055f57f4335362af895df7a3ee 155 Gene3D G3DSA:1.10.10.10 5 54 3.2E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_00690 beed72055f57f4335362af895df7a3ee 155 Pfam PF01037 Lrp/AsnC ligand binding domain 75 145 2.5E-10 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L04_00690 beed72055f57f4335362af895df7a3ee 155 SUPERFAMILY SSF46785 4 63 1.82E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_00690 beed72055f57f4335362af895df7a3ee 155 SUPERFAMILY SSF54909 74 151 2.95E-7 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L04_00690 beed72055f57f4335362af895df7a3ee 155 Pfam PF13404 AsnC-type helix-turn-helix domain 5 45 1.2E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_00690 beed72055f57f4335362af895df7a3ee 155 SMART SM00344 4 113 4.3E-38 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L04_08345 4cceb64cb59f2cec75755aca71d1a419 339 Gene3D G3DSA:1.10.3720.10 92 334 3.6E-17 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_08345 4cceb64cb59f2cec75755aca71d1a419 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 338 6.8E-48 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L04_08345 4cceb64cb59f2cec75755aca71d1a419 339 SUPERFAMILY SSF161098 95 321 1.9E-9 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_09555 566f6f9a9e798fa2ca77ad68ed27f0d7 429 SUPERFAMILY SSF52440 8 115 5.32E-34 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L04_09555 566f6f9a9e798fa2ca77ad68ed27f0d7 429 SUPERFAMILY SSF51246 339 410 2.9E-19 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A3L04_09555 566f6f9a9e798fa2ca77ad68ed27f0d7 429 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 18 410 2.8E-194 T 23-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 A3L04_09555 566f6f9a9e798fa2ca77ad68ed27f0d7 429 Pfam PF02222 ATP-grasp domain 127 303 8.9E-57 T 23-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type A3L04_09555 566f6f9a9e798fa2ca77ad68ed27f0d7 429 SUPERFAMILY SSF56059 118 324 1.33E-51 T 23-10-2018 A3L04_09555 566f6f9a9e798fa2ca77ad68ed27f0d7 429 Gene3D G3DSA:3.30.1490.20 129 200 6.2E-33 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L04_09555 566f6f9a9e798fa2ca77ad68ed27f0d7 429 Gene3D G3DSA:3.30.470.20 201 429 1.5E-82 T 23-10-2018 A3L04_09555 566f6f9a9e798fa2ca77ad68ed27f0d7 429 Gene3D G3DSA:3.40.50.20 1 128 1.2E-58 T 23-10-2018 A3L04_09555 566f6f9a9e798fa2ca77ad68ed27f0d7 429 Hamap MF_01643 Formate-dependent phosphoribosylglycinamide formyltransferase [purT]. 12 411 49.39 T 23-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 A3L04_03395 13bab3aa2f48e431481fe86ede697872 132 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 32 121 25.866 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03395 13bab3aa2f48e431481fe86ede697872 132 TIGRFAM TIGR01025 uS19_arch: ribosomal protein uS19 3 132 2.9E-71 T 23-10-2018 IPR005713 Ribosomal protein S19A/S15e GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03395 13bab3aa2f48e431481fe86ede697872 132 PRINTS PR00975 Ribosomal protein S19 family signature 97 112 3.3E-19 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03395 13bab3aa2f48e431481fe86ede697872 132 PRINTS PR00975 Ribosomal protein S19 family signature 65 84 3.3E-19 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03395 13bab3aa2f48e431481fe86ede697872 132 PRINTS PR00975 Ribosomal protein S19 family signature 85 97 3.3E-19 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03395 13bab3aa2f48e431481fe86ede697872 132 Pfam PF00203 Ribosomal protein S19 34 115 1.1E-36 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03395 13bab3aa2f48e431481fe86ede697872 132 SUPERFAMILY SSF54570 33 116 1.01E-31 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03395 13bab3aa2f48e431481fe86ede697872 132 PIRSF PIRSF002144 1 132 7.8E-41 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03395 13bab3aa2f48e431481fe86ede697872 132 ProSitePatterns PS00323 Ribosomal protein S19 signature. 85 109 - T 23-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03395 13bab3aa2f48e431481fe86ede697872 132 Gene3D G3DSA:3.30.860.20 1 132 4.1E-56 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_02025 4d35235667b9d3051365739aff9eca8b 588 Gene3D G3DSA:1.10.1140.10 438 588 2.7E-61 T 23-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L04_02025 4d35235667b9d3051365739aff9eca8b 588 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 214 437 8.9E-94 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L04_02025 4d35235667b9d3051365739aff9eca8b 588 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 2 586 55.559 T 23-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L04_02025 4d35235667b9d3051365739aff9eca8b 588 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 85 205 7.1E-50 T 23-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L04_02025 4d35235667b9d3051365739aff9eca8b 588 Gene3D G3DSA:3.40.50.300 73 437 1.3E-189 T 23-10-2018 A3L04_02025 4d35235667b9d3051365739aff9eca8b 588 SMART SM00382 226 414 0.0022 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_02025 4d35235667b9d3051365739aff9eca8b 588 Gene3D G3DSA:2.40.30.20 2 72 3.5E-31 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L04_02025 4d35235667b9d3051365739aff9eca8b 588 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 7 69 7.8E-15 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L04_02025 4d35235667b9d3051365739aff9eca8b 588 SUPERFAMILY SSF52540 148 443 1.03E-87 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_02025 4d35235667b9d3051365739aff9eca8b 588 Gene3D G3DSA:2.40.50.100 116 187 1.3E-189 T 23-10-2018 A3L04_02025 4d35235667b9d3051365739aff9eca8b 588 TIGRFAM TIGR01043 ATP_syn_A_arch: ATP synthase archaeal, A subunit 4 583 0.0 T 23-10-2018 IPR005726 ATP synthase alpha chain, archaea GO:0015986|GO:0033178|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L04_02025 4d35235667b9d3051365739aff9eca8b 588 SUPERFAMILY SSF50615 4 71 6.02E-14 T 23-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L04_02025 4d35235667b9d3051365739aff9eca8b 588 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 428 437 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L04_02025 4d35235667b9d3051365739aff9eca8b 588 SUPERFAMILY SSF47917 450 556 4.55E-28 T 23-10-2018 A3L04_04320 bf737761df377fa8ac3970d38dee6087 122 PIRSF PIRSF014543 1 121 4.9E-47 T 23-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 A3L04_04320 bf737761df377fa8ac3970d38dee6087 122 Pfam PF12646 Domain of unknown function (DUF3783) 55 109 1.3E-16 T 23-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 A3L04_05930 08dbea7b048cefd80e78f90af89882c2 171 SUPERFAMILY SSF89028 1 165 1.75E-48 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L04_05930 08dbea7b048cefd80e78f90af89882c2 171 Pfam PF01923 Cobalamin adenosyltransferase 3 158 2.6E-46 T 23-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L04_05930 08dbea7b048cefd80e78f90af89882c2 171 Gene3D G3DSA:1.20.1200.10 24 171 1.6E-49 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L04_05930 08dbea7b048cefd80e78f90af89882c2 171 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 168 2.1E-58 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L04_05930 08dbea7b048cefd80e78f90af89882c2 171 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 14 134 1.0E-49 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L04_04015 2fbb81d147a5fb124be8f5ef609647ca 144 Gene3D G3DSA:3.40.1360.10 3 115 3.4E-21 T 23-10-2018 A3L04_04015 2fbb81d147a5fb124be8f5ef609647ca 144 Hamap MF_01095 UPF0292 protein . 3 122 32.092 T 23-10-2018 IPR022972 Uncharacterised protein family UPF0292 A3L04_04015 2fbb81d147a5fb124be8f5ef609647ca 144 SMART SM00493 20 90 3.2E-5 T 23-10-2018 IPR006171 TOPRIM domain A3L04_04015 2fbb81d147a5fb124be8f5ef609647ca 144 Pfam PF01751 Toprim domain 22 87 1.7E-5 T 23-10-2018 IPR006171 TOPRIM domain A3L04_04015 2fbb81d147a5fb124be8f5ef609647ca 144 SUPERFAMILY SSF110455 20 87 4.05E-7 T 23-10-2018 A3L04_08335 9ff555b0de7c418636ebc3cde8a595de 67 Pfam PF02597 ThiS family 10 67 7.1E-12 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L04_08335 9ff555b0de7c418636ebc3cde8a595de 67 SUPERFAMILY SSF54285 4 67 2.33E-13 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L04_08335 9ff555b0de7c418636ebc3cde8a595de 67 Gene3D G3DSA:3.10.20.30 1 67 9.7E-28 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L04_10335 f5a9f509eef15db9a2b6fef97f93c4ad 567 Gene3D G3DSA:3.40.50.300 328 532 6.8E-21 T 23-10-2018 A3L04_10335 f5a9f509eef15db9a2b6fef97f93c4ad 567 PIRSF PIRSF029254 1 560 2.3E-217 T 23-10-2018 IPR012401 DNA-binding protein MutS2, archaea A3L04_10335 f5a9f509eef15db9a2b6fef97f93c4ad 567 Pfam PF00488 MutS domain V 375 457 5.1E-7 T 23-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A3L04_10335 f5a9f509eef15db9a2b6fef97f93c4ad 567 SMART SM00534 371 559 5.1E-32 T 23-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A3L04_10335 f5a9f509eef15db9a2b6fef97f93c4ad 567 Hamap MF_00971 DNA-binding protein MutS2 [mutS2]. 1 558 24.918 T 23-10-2018 IPR012401 DNA-binding protein MutS2, archaea A3L04_10335 f5a9f509eef15db9a2b6fef97f93c4ad 567 SUPERFAMILY SSF52540 367 537 1.07E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_10750 44c75eaa9263c86dfc222bf527829272 397 SUPERFAMILY SSF81271 322 393 5.1E-18 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A3L04_10750 44c75eaa9263c86dfc222bf527829272 397 Gene3D G3DSA:3.10.20.30 319 397 6.3E-32 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L04_10750 44c75eaa9263c86dfc222bf527829272 397 Pfam PF02824 TGS domain 345 393 6.0E-11 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A3L04_10750 44c75eaa9263c86dfc222bf527829272 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 92 110 7.6E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_10750 44c75eaa9263c86dfc222bf527829272 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 3 23 7.6E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_10750 44c75eaa9263c86dfc222bf527829272 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 75 90 7.6E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_10750 44c75eaa9263c86dfc222bf527829272 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 24 42 7.6E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_10750 44c75eaa9263c86dfc222bf527829272 397 SUPERFAMILY SSF52540 1 315 6.49E-73 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_10750 44c75eaa9263c86dfc222bf527829272 397 Pfam PF01926 50S ribosome-binding GTPase 2 121 2.8E-19 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_10750 44c75eaa9263c86dfc222bf527829272 397 Gene3D G3DSA:1.10.8.470 126 215 3.4E-32 T 23-10-2018 A3L04_10750 44c75eaa9263c86dfc222bf527829272 397 Pfam PF08438 GTPase of unknown function C-terminal 220 327 9.0E-37 T 23-10-2018 IPR013646 Uncharacterised GTP-binding protein, C-terminal A3L04_04805 0b9116a52e4160bd92e546a9077163f0 907 Gene3D G3DSA:2.20.25.410 850 900 4.8E-22 T 23-10-2018 A3L04_04805 0b9116a52e4160bd92e546a9077163f0 907 Gene3D G3DSA:3.30.1490.180 354 418 3.8E-82 T 23-10-2018 A3L04_04805 0b9116a52e4160bd92e546a9077163f0 907 Gene3D G3DSA:1.10.274.100 491 670 7.0E-66 T 23-10-2018 A3L04_04805 0b9116a52e4160bd92e546a9077163f0 907 SMART SM00663 211 515 1.6E-210 T 23-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04805 0b9116a52e4160bd92e546a9077163f0 907 Gene3D G3DSA:1.20.120.1280 235 284 1.4E-11 T 23-10-2018 A3L04_04805 0b9116a52e4160bd92e546a9077163f0 907 Gene3D G3DSA:1.20.120.1280 1 122 7.0E-32 T 23-10-2018 A3L04_04805 0b9116a52e4160bd92e546a9077163f0 907 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 319 6.5E-110 T 23-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04805 0b9116a52e4160bd92e546a9077163f0 907 Pfam PF00623 RNA polymerase Rpb1, domain 2 321 487 2.0E-75 T 23-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04805 0b9116a52e4160bd92e546a9077163f0 907 Pfam PF05000 RNA polymerase Rpb1, domain 4 698 804 3.9E-31 T 23-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04805 0b9116a52e4160bd92e546a9077163f0 907 Pfam PF04998 RNA polymerase Rpb1, domain 5 811 876 5.9E-29 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04805 0b9116a52e4160bd92e546a9077163f0 907 Gene3D G3DSA:1.10.132.30 671 813 1.2E-45 T 23-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04805 0b9116a52e4160bd92e546a9077163f0 907 TIGRFAM TIGR02390 RNA_pol_rpoA1: DNA-directed RNA polymerase subunit A' 5 894 0.0 T 23-10-2018 IPR012758 DNA-directed RNA polymerase subunit A' (Rpo1N) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04805 0b9116a52e4160bd92e546a9077163f0 907 Gene3D G3DSA:2.40.40.20 311 482 3.8E-82 T 23-10-2018 A3L04_04805 0b9116a52e4160bd92e546a9077163f0 907 Pfam PF04983 RNA polymerase Rpb1, domain 3 490 672 2.7E-39 T 23-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04805 0b9116a52e4160bd92e546a9077163f0 907 SUPERFAMILY SSF64484 3 887 0.0 T 23-10-2018 A3L04_06610 267cc326dbc9f76dd1d48582b3caed9f 305 SMART SM00849 19 208 8.6E-4 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_06610 267cc326dbc9f76dd1d48582b3caed9f 305 Pfam PF12706 Beta-lactamase superfamily domain 32 153 1.2E-10 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_06610 267cc326dbc9f76dd1d48582b3caed9f 305 Pfam PF12706 Beta-lactamase superfamily domain 198 263 2.1E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_06610 267cc326dbc9f76dd1d48582b3caed9f 305 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 3 293 3.7E-94 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 A3L04_06610 267cc326dbc9f76dd1d48582b3caed9f 305 Gene3D G3DSA:3.60.15.10 2 295 6.3E-83 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_06610 267cc326dbc9f76dd1d48582b3caed9f 305 Hamap MF_01818 Ribonuclease BN [rbn]. 2 295 32.407 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 A3L04_06610 267cc326dbc9f76dd1d48582b3caed9f 305 SUPERFAMILY SSF56281 3 293 6.62E-70 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_03185 14cedf8e636e56713bb82458aeec9bf9 280 Pfam PF00005 ABC transporter 21 172 4.3E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_03185 14cedf8e636e56713bb82458aeec9bf9 280 Gene3D G3DSA:3.40.50.300 1 277 5.5E-74 T 23-10-2018 A3L04_03185 14cedf8e636e56713bb82458aeec9bf9 280 SMART SM00382 30 229 4.5E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_03185 14cedf8e636e56713bb82458aeec9bf9 280 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_03185 14cedf8e636e56713bb82458aeec9bf9 280 SUPERFAMILY SSF52540 3 234 7.28E-62 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_04400 63c693e850485b717df1d4a8f3f0e494 202 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 112 136 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A3L04_04400 63c693e850485b717df1d4a8f3f0e494 202 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 9 20 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A3L04_04400 63c693e850485b717df1d4a8f3f0e494 202 PRINTS PR00395 Ribosomal protein S2 signature 39 48 2.3E-30 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_04400 63c693e850485b717df1d4a8f3f0e494 202 PRINTS PR00395 Ribosomal protein S2 signature 9 27 2.3E-30 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_04400 63c693e850485b717df1d4a8f3f0e494 202 PRINTS PR00395 Ribosomal protein S2 signature 129 140 2.3E-30 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_04400 63c693e850485b717df1d4a8f3f0e494 202 PRINTS PR00395 Ribosomal protein S2 signature 112 129 2.3E-30 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_04400 63c693e850485b717df1d4a8f3f0e494 202 PRINTS PR00395 Ribosomal protein S2 signature 87 104 2.3E-30 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_04400 63c693e850485b717df1d4a8f3f0e494 202 PRINTS PR00395 Ribosomal protein S2 signature 150 164 2.3E-30 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_04400 63c693e850485b717df1d4a8f3f0e494 202 Pfam PF00318 Ribosomal protein S2 13 103 2.8E-10 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_04400 63c693e850485b717df1d4a8f3f0e494 202 Pfam PF00318 Ribosomal protein S2 111 175 6.5E-14 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_04400 63c693e850485b717df1d4a8f3f0e494 202 SUPERFAMILY SSF52313 5 193 1.27E-61 T 23-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily A3L04_04400 63c693e850485b717df1d4a8f3f0e494 202 Hamap MF_00291_A 30S ribosomal protein S2 [rpsB]. 1 199 50.088 T 23-10-2018 IPR023454 Ribosomal protein S2, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_04400 63c693e850485b717df1d4a8f3f0e494 202 TIGRFAM TIGR01012 uS2_euk_arch: ribosomal protein uS2 4 198 6.2E-102 T 23-10-2018 IPR005707 Ribosomal protein S2, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_04400 63c693e850485b717df1d4a8f3f0e494 202 Gene3D G3DSA:3.40.50.10490 8 201 2.7E-71 T 23-10-2018 A3L04_05215 221162fa9fc8196172c7be498d094901 382 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 2 374 1.1E-109 T 23-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 A3L04_05215 221162fa9fc8196172c7be498d094901 382 Pfam PF01979 Amidohydrolase family 47 377 3.4E-29 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A3L04_05215 221162fa9fc8196172c7be498d094901 382 Gene3D G3DSA:2.30.40.10 10 375 5.9E-140 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L04_05215 221162fa9fc8196172c7be498d094901 382 SUPERFAMILY SSF51556 51 346 1.13E-102 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L04_05215 221162fa9fc8196172c7be498d094901 382 SUPERFAMILY SSF51338 1 380 6.43E-19 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L04_05215 221162fa9fc8196172c7be498d094901 382 Gene3D G3DSA:3.20.20.140 51 348 5.9E-140 T 23-10-2018 A3L04_05215 221162fa9fc8196172c7be498d094901 382 PIRSF PIRSF038994 1 381 1.9E-137 T 23-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 Pfam PF08264 Anticodon-binding domain of tRNA 429 519 1.8E-11 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 548 1.5E-176 T 23-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 Gene3D G3DSA:1.10.730.10 397 547 8.1E-112 T 23-10-2018 A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 Hamap MF_00098 Methionine--tRNA ligase [metG]. 2 559 43.313 T 23-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 Gene3D G3DSA:1.10.730.10 340 578 8.1E-112 T 23-10-2018 A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 603 724 1.6E-38 T 23-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 Pfam PF01588 Putative tRNA binding domain 630 721 2.8E-33 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 SUPERFAMILY SSF52374 3 394 3.22E-108 T 23-10-2018 A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 1.4E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 1.4E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 PRINTS PR01041 Methionyl-tRNA synthetase signature 293 308 1.4E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 PRINTS PR01041 Methionyl-tRNA synthetase signature 251 262 1.4E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 1.4E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 PRINTS PR01041 Methionyl-tRNA synthetase signature 395 406 1.4E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 Gene3D G3DSA:2.40.50.140 618 724 4.0E-46 T 23-10-2018 A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 SUPERFAMILY SSF57770 139 173 1.01E-10 T 23-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 Pfam PF09334 tRNA synthetases class I (M) 4 408 3.2E-160 T 23-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 Gene3D G3DSA:2.170.220.10 98 251 1.9E-145 T 23-10-2018 A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 SUPERFAMILY SSF47323 397 637 5.79E-46 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 SUPERFAMILY SSF50249 623 723 2.94E-38 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_05255 bef6c78c0f0249daae50270057b596cb 724 Gene3D G3DSA:3.40.50.620 5 315 1.9E-145 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_03520 cd1e515b9c3fc6240c2fc6d95311c095 168 Gene3D G3DSA:3.30.70.20 47 93 8.5E-12 T 23-10-2018 A3L04_03520 cd1e515b9c3fc6240c2fc6d95311c095 168 Pfam PF00037 4Fe-4S binding domain 67 88 3.8E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L04_03520 cd1e515b9c3fc6240c2fc6d95311c095 168 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 74 85 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_03520 cd1e515b9c3fc6240c2fc6d95311c095 168 SUPERFAMILY SSF54862 4 139 4.19E-19 T 23-10-2018 A3L04_04280 165533802de4a836e10ac6b5405fffb7 260 SUPERFAMILY SSF52540 3 228 1.23E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_04280 165533802de4a836e10ac6b5405fffb7 260 Gene3D G3DSA:3.40.50.300 1 248 3.5E-66 T 23-10-2018 A3L04_04280 165533802de4a836e10ac6b5405fffb7 260 Pfam PF00005 ABC transporter 21 166 1.4E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_04280 165533802de4a836e10ac6b5405fffb7 260 SMART SM00382 29 223 3.2E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_04280 165533802de4a836e10ac6b5405fffb7 260 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_10315 e5d7ce176ee1c3cf51102df79f422837 113 Gene3D G3DSA:2.30.130.30 1 113 7.0E-42 T 23-10-2018 A3L04_10315 e5d7ce176ee1c3cf51102df79f422837 113 Pfam PF04266 ASCH domain 7 107 6.8E-13 T 23-10-2018 IPR007374 ASCH domain A3L04_10315 e5d7ce176ee1c3cf51102df79f422837 113 SMART SM01022 6 109 7.9E-9 T 23-10-2018 IPR007374 ASCH domain A3L04_10315 e5d7ce176ee1c3cf51102df79f422837 113 PIRSF PIRSF016134 2 111 5.6E-45 T 23-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 A3L04_10315 e5d7ce176ee1c3cf51102df79f422837 113 SUPERFAMILY SSF88697 1 108 1.86E-32 T 23-10-2018 IPR015947 PUA-like superfamily A3L04_09265 f926c926016e01b98253e1d8a4e4a380 384 Pfam PF13439 Glycosyltransferase Family 4 17 184 1.7E-30 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L04_09265 f926c926016e01b98253e1d8a4e4a380 384 SUPERFAMILY SSF53756 5 378 8.38E-97 T 23-10-2018 A3L04_09265 f926c926016e01b98253e1d8a4e4a380 384 Pfam PF00534 Glycosyl transferases group 1 197 352 9.7E-40 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L04_09265 f926c926016e01b98253e1d8a4e4a380 384 Gene3D G3DSA:3.40.50.2000 2 208 2.5E-43 T 23-10-2018 A3L04_09265 f926c926016e01b98253e1d8a4e4a380 384 Gene3D G3DSA:3.40.50.2000 209 365 1.5E-46 T 23-10-2018 A3L04_04950 b70533b6bfdebeab901b903ba329c740 170 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 154 4.2E-42 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A3L04_04950 b70533b6bfdebeab901b903ba329c740 170 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 151 2.8E-32 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L04_04950 b70533b6bfdebeab901b903ba329c740 170 Gene3D G3DSA:3.60.21.10 1 159 1.2E-50 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L04_04950 b70533b6bfdebeab901b903ba329c740 170 SUPERFAMILY SSF56300 1 157 3.8E-38 T 23-10-2018 A3L04_08770 ddbd77f58011c0ea480075da6e25e700 75 SUPERFAMILY SSF50037 5 74 8.24E-15 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal A3L04_08770 ddbd77f58011c0ea480075da6e25e700 75 SMART SM00899 3 74 1.5E-18 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A3L04_08770 ddbd77f58011c0ea480075da6e25e700 75 Pfam PF04023 FeoA domain 3 74 6.5E-19 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A3L04_08770 ddbd77f58011c0ea480075da6e25e700 75 Gene3D G3DSA:2.30.30.90 12 74 1.7E-18 T 23-10-2018 IPR038157 Ferrous iron transporter, core domain A3L04_09060 17f6260f893017fda49b68ca7fb8e8c8 385 TIGRFAM TIGR02580 cas_RAMP_Cmr4: CRISPR type III-B/RAMP module RAMP protein Cmr4 108 369 6.3E-53 T 23-10-2018 IPR013410 CRISPR-associated RAMP Cmr4 A3L04_09060 17f6260f893017fda49b68ca7fb8e8c8 385 Pfam PF03787 RAMP superfamily 15 369 1.5E-33 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein A3L04_06690 a9ecbee54897ab2b267b7d3a738af61f 220 ProSitePatterns PS00113 Adenylate kinase signature. 79 90 - T 23-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L04_06690 a9ecbee54897ab2b267b7d3a738af61f 220 Pfam PF00406 Adenylate kinase 5 188 9.3E-41 T 23-10-2018 A3L04_06690 a9ecbee54897ab2b267b7d3a738af61f 220 Gene3D G3DSA:3.40.50.300 1 218 2.6E-76 T 23-10-2018 A3L04_06690 a9ecbee54897ab2b267b7d3a738af61f 220 Pfam PF05191 Adenylate kinase, active site lid 125 160 1.8E-19 T 23-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A3L04_06690 a9ecbee54897ab2b267b7d3a738af61f 220 PRINTS PR00094 Adenylate kinase signature 158 173 2.2E-29 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L04_06690 a9ecbee54897ab2b267b7d3a738af61f 220 PRINTS PR00094 Adenylate kinase signature 32 46 2.2E-29 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L04_06690 a9ecbee54897ab2b267b7d3a738af61f 220 PRINTS PR00094 Adenylate kinase signature 79 95 2.2E-29 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L04_06690 a9ecbee54897ab2b267b7d3a738af61f 220 PRINTS PR00094 Adenylate kinase signature 4 17 2.2E-29 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L04_06690 a9ecbee54897ab2b267b7d3a738af61f 220 PRINTS PR00094 Adenylate kinase signature 175 189 2.2E-29 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L04_06690 a9ecbee54897ab2b267b7d3a738af61f 220 TIGRFAM TIGR01351 adk: adenylate kinase 2 209 1.4E-74 T 23-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A3L04_06690 a9ecbee54897ab2b267b7d3a738af61f 220 Hamap MF_00235 Adenylate kinase [adk]. 1 211 46.202 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L04_06690 a9ecbee54897ab2b267b7d3a738af61f 220 SUPERFAMILY SSF52540 1 212 1.93E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_02245 161ef0e2beac00ecc4d9e31fc9ddf8c1 204 SMART SM00471 33 146 9.2E-13 T 23-10-2018 IPR003607 HD/PDEase domain A3L04_02245 161ef0e2beac00ecc4d9e31fc9ddf8c1 204 TIGRFAM TIGR00277 HDIG: HDIG domain 35 105 9.8E-8 T 23-10-2018 IPR006675 HDIG domain A3L04_02245 161ef0e2beac00ecc4d9e31fc9ddf8c1 204 Gene3D G3DSA:1.10.3210.50 22 204 1.9E-58 T 23-10-2018 A3L04_02245 161ef0e2beac00ecc4d9e31fc9ddf8c1 204 SUPERFAMILY SSF109604 34 201 5.56E-54 T 23-10-2018 A3L04_02245 161ef0e2beac00ecc4d9e31fc9ddf8c1 204 Pfam PF01966 HD domain 38 136 5.8E-18 T 23-10-2018 IPR006674 HD domain A3L04_07365 6f46c32966dd941d1faf5926095dc790 97 Pfam PF04010 Protein of unknown function (DUF357) 14 86 4.2E-30 T 23-10-2018 IPR023140 Domain of unknown function DUF357 A3L04_07365 6f46c32966dd941d1faf5926095dc790 97 SUPERFAMILY SSF158372 6 87 8.37E-26 T 23-10-2018 IPR036809 AF1782-like superfamily A3L04_07365 6f46c32966dd941d1faf5926095dc790 97 Gene3D G3DSA:1.20.1270.90 3 86 1.8E-25 T 23-10-2018 A3L04_03880 0ec791755eded0065f7a766220c35942 328 SUPERFAMILY SSF50129 1 167 8.67E-45 T 23-10-2018 IPR011032 GroES-like superfamily A3L04_03880 0ec791755eded0065f7a766220c35942 328 SUPERFAMILY SSF51735 132 291 2.47E-24 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_03880 0ec791755eded0065f7a766220c35942 328 Pfam PF16912 Glucose dehydrogenase C-terminus 159 324 1.3E-11 T 23-10-2018 IPR031640 Glucose dehydrogenase, C-terminal KEGG: 00030+1.1.1.47 A3L04_03880 0ec791755eded0065f7a766220c35942 328 Gene3D G3DSA:3.90.180.10 13 315 5.5E-79 T 23-10-2018 A3L04_03880 0ec791755eded0065f7a766220c35942 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 128 3.3E-29 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A3L04_03880 0ec791755eded0065f7a766220c35942 328 Gene3D G3DSA:3.40.50.720 146 277 5.5E-79 T 23-10-2018 A3L04_08205 c77f049b40c5b21e9374bcc3d9445c33 456 Gene3D G3DSA:3.40.50.300 1 167 7.6E-35 T 23-10-2018 A3L04_08205 c77f049b40c5b21e9374bcc3d9445c33 456 Pfam PF01637 ATPase domain predominantly from Archaea 2 202 5.0E-36 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_08205 c77f049b40c5b21e9374bcc3d9445c33 456 SUPERFAMILY SSF46785 240 319 1.72E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_08205 c77f049b40c5b21e9374bcc3d9445c33 456 Pfam PF03008 Archaea bacterial proteins of unknown function 309 406 5.3E-31 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L04_08205 c77f049b40c5b21e9374bcc3d9445c33 456 SUPERFAMILY SSF52540 2 241 1.48E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_08205 c77f049b40c5b21e9374bcc3d9445c33 456 Pfam PF09339 IclR helix-turn-helix domain 242 284 4.8E-5 T 23-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A3L04_04545 8aec3b1daec40ea4e6883f2d8a4ee789 129 Pfam PF09868 Uncharacterized protein conserved in archaea (DUF2095) 3 129 6.3E-73 T 23-10-2018 IPR018662 Protein of unknown function DUF2095 A3L04_04635 e344e9dd2f6fe7483b458f7f64816486 138 Gene3D G3DSA:2.20.28.10 69 123 1.2E-27 T 23-10-2018 A3L04_04635 e344e9dd2f6fe7483b458f7f64816486 138 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 132 1.2E-27 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 A3L04_04635 e344e9dd2f6fe7483b458f7f64816486 138 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 23-10-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site A3L04_04635 e344e9dd2f6fe7483b458f7f64816486 138 Gene3D G3DSA:3.30.2320.50 2 129 1.2E-27 T 23-10-2018 A3L04_04635 e344e9dd2f6fe7483b458f7f64816486 138 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 134 21.241 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 A3L04_04635 e344e9dd2f6fe7483b458f7f64816486 138 PIRSF PIRSF004761 1 137 1.2E-35 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 A3L04_00055 8a5f0bc1089b5222862ea83e8696931e 263 SUPERFAMILY SSF51735 12 261 4.41E-74 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_00055 8a5f0bc1089b5222862ea83e8696931e 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 4.2E-12 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_00055 8a5f0bc1089b5222862ea83e8696931e 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 4.2E-12 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_00055 8a5f0bc1089b5222862ea83e8696931e 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 4.2E-12 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_00055 8a5f0bc1089b5222862ea83e8696931e 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 9.5E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_00055 8a5f0bc1089b5222862ea83e8696931e 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 9.5E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_00055 8a5f0bc1089b5222862ea83e8696931e 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 9.5E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_00055 8a5f0bc1089b5222862ea83e8696931e 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 9.5E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_00055 8a5f0bc1089b5222862ea83e8696931e 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 9.5E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_00055 8a5f0bc1089b5222862ea83e8696931e 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 9.5E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_00055 8a5f0bc1089b5222862ea83e8696931e 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 260 3.9E-56 T 23-10-2018 A3L04_00055 8a5f0bc1089b5222862ea83e8696931e 263 Gene3D G3DSA:3.40.50.720 2 262 9.3E-76 T 23-10-2018 A3L04_04995 111900e2b2b8188cb073bfc2df6d4d16 151 Gene3D G3DSA:1.10.10.10 2 56 5.2E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_04995 111900e2b2b8188cb073bfc2df6d4d16 151 Pfam PF01037 Lrp/AsnC ligand binding domain 71 140 1.3E-19 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L04_04995 111900e2b2b8188cb073bfc2df6d4d16 151 SMART SM00344 5 111 1.0E-52 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L04_04995 111900e2b2b8188cb073bfc2df6d4d16 151 SUPERFAMILY SSF54909 65 150 4.96E-23 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L04_04995 111900e2b2b8188cb073bfc2df6d4d16 151 Gene3D G3DSA:3.30.70.920 57 151 8.6E-30 T 23-10-2018 A3L04_04995 111900e2b2b8188cb073bfc2df6d4d16 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 2.8E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_04995 111900e2b2b8188cb073bfc2df6d4d16 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 2.8E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_04995 111900e2b2b8188cb073bfc2df6d4d16 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 2.8E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_04995 111900e2b2b8188cb073bfc2df6d4d16 151 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 52 2.1E-15 T 23-10-2018 A3L04_04995 111900e2b2b8188cb073bfc2df6d4d16 151 SUPERFAMILY SSF46785 4 65 1.07E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_08135 0b7c8bdd05ed6934bcc86131742eb239 439 SUPERFAMILY SSF52980 331 391 4.11E-5 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L04_08135 0b7c8bdd05ed6934bcc86131742eb239 439 Gene3D G3DSA:3.40.50.300 59 161 1.1E-14 T 23-10-2018 A3L04_08135 0b7c8bdd05ed6934bcc86131742eb239 439 Pfam PF03008 Archaea bacterial proteins of unknown function 301 396 2.0E-31 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L04_08135 0b7c8bdd05ed6934bcc86131742eb239 439 SUPERFAMILY SSF46785 233 308 4.96E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_08135 0b7c8bdd05ed6934bcc86131742eb239 439 Pfam PF01637 ATPase domain predominantly from Archaea 5 196 3.4E-26 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_08135 0b7c8bdd05ed6934bcc86131742eb239 439 SUPERFAMILY SSF52540 4 233 2.8E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_03225 fa8e5093d3ac54a0b7d0923c8f75526a 463 TIGRFAM TIGR00797 matE: MATE efflux family protein 14 410 1.2E-139 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L04_03225 fa8e5093d3ac54a0b7d0923c8f75526a 463 PIRSF PIRSF006603 1 463 2.8E-110 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L04_03225 fa8e5093d3ac54a0b7d0923c8f75526a 463 Pfam PF01554 MatE 238 404 6.0E-36 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L04_03225 fa8e5093d3ac54a0b7d0923c8f75526a 463 Pfam PF01554 MatE 14 174 7.8E-40 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L04_10370 bbf44464eb5caf27b7db66969a8c3e8e 339 SMART SM00788 3 334 8.9E-161 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L04_10370 bbf44464eb5caf27b7db66969a8c3e8e 339 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 23-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L04_10370 bbf44464eb5caf27b7db66969a8c3e8e 339 SUPERFAMILY SSF52540 1 335 9.03E-108 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_10370 bbf44464eb5caf27b7db66969a8c3e8e 339 Pfam PF00709 Adenylosuccinate synthetase 150 289 5.6E-43 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L04_10370 bbf44464eb5caf27b7db66969a8c3e8e 339 Pfam PF00709 Adenylosuccinate synthetase 290 333 5.8E-6 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L04_10370 bbf44464eb5caf27b7db66969a8c3e8e 339 Pfam PF00709 Adenylosuccinate synthetase 5 149 1.2E-38 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L04_10370 bbf44464eb5caf27b7db66969a8c3e8e 339 Gene3D G3DSA:3.40.440.10 1 339 2.2E-140 T 23-10-2018 A3L04_10370 bbf44464eb5caf27b7db66969a8c3e8e 339 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 339 99.468 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L04_05435 1ba9a26e30efa18783a4d05a594af8b8 151 SUPERFAMILY SSF54197 1 127 2.41E-39 T 23-10-2018 IPR036265 HIT-like superfamily A3L04_05435 1ba9a26e30efa18783a4d05a594af8b8 151 Pfam PF01230 HIT domain 9 102 2.8E-24 T 23-10-2018 IPR001310 Histidine triad (HIT) protein A3L04_05435 1ba9a26e30efa18783a4d05a594af8b8 151 Gene3D G3DSA:3.30.428.10 1 137 1.0E-38 T 23-10-2018 IPR036265 HIT-like superfamily A3L04_05435 1ba9a26e30efa18783a4d05a594af8b8 151 ProSitePatterns PS00892 HIT domain signature. 81 99 - T 23-10-2018 IPR019808 Histidine triad, conserved site A3L04_00390 024510b93816c43e74cda4a65e7b8da1 341 Hamap MF_00280 50S ribosomal protein L10 [rpl10]. 1 284 36.276 T 23-10-2018 IPR022909 50S ribosomal protein L10, archaea A3L04_00390 024510b93816c43e74cda4a65e7b8da1 341 Gene3D G3DSA:3.90.105.20 108 187 9.4E-71 T 23-10-2018 A3L04_00390 024510b93816c43e74cda4a65e7b8da1 341 Gene3D G3DSA:3.30.70.1730 15 211 9.4E-71 T 23-10-2018 A3L04_00390 024510b93816c43e74cda4a65e7b8da1 341 SUPERFAMILY SSF160369 5 143 2.48E-24 T 23-10-2018 A3L04_00390 024510b93816c43e74cda4a65e7b8da1 341 Pfam PF00428 60s Acidic ribosomal protein 233 340 1.1E-9 T 23-10-2018 A3L04_00390 024510b93816c43e74cda4a65e7b8da1 341 Pfam PF00466 Ribosomal protein L10 5 106 8.5E-22 T 23-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 A3L04_08420 1ec68541aa463ad380c7034ad3b0ef98 376 SUPERFAMILY SSF53633 1 268 1.05E-52 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L04_08420 1ec68541aa463ad380c7034ad3b0ef98 376 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 23-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A3L04_08420 1ec68541aa463ad380c7034ad3b0ef98 376 TIGRFAM TIGR02078 AspKin_pair: putative Pyrococcus aspartate kinase subunit 1 327 2.4E-143 T 23-10-2018 IPR011819 Pyrococcus aspartate kinase subunit, putative A3L04_08420 1ec68541aa463ad380c7034ad3b0ef98 376 Pfam PF00696 Amino acid kinase family 1 251 2.1E-38 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A3L04_08420 1ec68541aa463ad380c7034ad3b0ef98 376 Gene3D G3DSA:3.40.1160.10 1 269 5.8E-54 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L04_02585 a6dbee8994bafba752fe75972433702a 478 SUPERFAMILY SSF64153 4 225 4.97E-52 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 A3L04_02585 a6dbee8994bafba752fe75972433702a 478 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 215 475 4.7E-72 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A3L04_02585 a6dbee8994bafba752fe75972433702a 478 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 8 183 7.1E-44 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A3L04_02585 a6dbee8994bafba752fe75972433702a 478 PIRSF PIRSF017184 2 478 1.0E-100 T 23-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 A3L04_02585 a6dbee8994bafba752fe75972433702a 478 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 204 476 22.462 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A3L04_02585 a6dbee8994bafba752fe75972433702a 478 Pfam PF03853 YjeF-related protein N-terminus 22 182 4.5E-36 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A3L04_02585 a6dbee8994bafba752fe75972433702a 478 Pfam PF01256 Carbohydrate kinase 227 470 1.9E-54 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A3L04_02585 a6dbee8994bafba752fe75972433702a 478 Gene3D G3DSA:3.40.1190.20 213 477 2.6E-79 T 23-10-2018 IPR029056 Ribokinase-like A3L04_02585 a6dbee8994bafba752fe75972433702a 478 Gene3D G3DSA:3.40.50.10260 9 212 4.7E-46 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 A3L04_02585 a6dbee8994bafba752fe75972433702a 478 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 1 198 18.848 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A3L04_02585 a6dbee8994bafba752fe75972433702a 478 SUPERFAMILY SSF53613 212 475 8.61E-65 T 23-10-2018 IPR029056 Ribokinase-like A3L04_02585 a6dbee8994bafba752fe75972433702a 478 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 415 425 - T 23-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site A3L04_09915 4f0efcd5b321d4df8bd99b1e68fe8182 268 Pfam PF13559 Domain of unknown function (DUF4129) 197 261 2.2E-7 T 23-10-2018 IPR025403 Domain of unknown function DUF4129 A3L04_05675 ea616515b3e17cd984ccf3953aa2cd60 459 Pfam PF01637 ATPase domain predominantly from Archaea 3 202 4.3E-12 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_05675 ea616515b3e17cd984ccf3953aa2cd60 459 Gene3D G3DSA:3.40.50.300 1 168 8.8E-23 T 23-10-2018 A3L04_05675 ea616515b3e17cd984ccf3953aa2cd60 459 SUPERFAMILY SSF52540 2 222 1.26E-26 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_05675 ea616515b3e17cd984ccf3953aa2cd60 459 Pfam PF03008 Archaea bacterial proteins of unknown function 315 409 1.6E-14 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L04_08680 e3f6a0f5c57e7d53af734af1cb31a292 455 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 447 1.2E-181 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08680 e3f6a0f5c57e7d53af734af1cb31a292 455 Gene3D G3DSA:3.40.120.10 1 152 1.1E-64 T 23-10-2018 A3L04_08680 e3f6a0f5c57e7d53af734af1cb31a292 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 6.9E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08680 e3f6a0f5c57e7d53af734af1cb31a292 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 208 221 6.9E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08680 e3f6a0f5c57e7d53af734af1cb31a292 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 6.9E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08680 e3f6a0f5c57e7d53af734af1cb31a292 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 6.9E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08680 e3f6a0f5c57e7d53af734af1cb31a292 455 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 393 443 8.8E-13 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08680 e3f6a0f5c57e7d53af734af1cb31a292 455 Gene3D G3DSA:3.40.120.10 169 358 4.3E-77 T 23-10-2018 A3L04_08680 e3f6a0f5c57e7d53af734af1cb31a292 455 SUPERFAMILY SSF53738 155 259 3.53E-31 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08680 e3f6a0f5c57e7d53af734af1cb31a292 455 SUPERFAMILY SSF53738 261 367 1.65E-26 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08680 e3f6a0f5c57e7d53af734af1cb31a292 455 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 137 7.8E-49 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08680 e3f6a0f5c57e7d53af734af1cb31a292 455 Gene3D G3DSA:3.40.120.10 257 365 4.3E-77 T 23-10-2018 A3L04_08680 e3f6a0f5c57e7d53af734af1cb31a292 455 SUPERFAMILY SSF55957 358 455 2.35E-23 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08680 e3f6a0f5c57e7d53af734af1cb31a292 455 Gene3D G3DSA:3.30.310.50 371 455 1.1E-32 T 23-10-2018 A3L04_08680 e3f6a0f5c57e7d53af734af1cb31a292 455 SUPERFAMILY SSF53738 3 180 1.53E-49 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08680 e3f6a0f5c57e7d53af734af1cb31a292 455 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 261 370 9.9E-28 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_08680 e3f6a0f5c57e7d53af734af1cb31a292 455 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 256 1.9E-30 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_01670 2772231e3db487d288a7d77c0fcf9422 396 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 174 307 2.2E-44 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L04_01670 2772231e3db487d288a7d77c0fcf9422 396 Pfam PF16450 Proteasomal ATPase OB/ID domain 63 119 3.3E-8 T 23-10-2018 IPR032501 Proteasomal ATPase, OB/ID domain A3L04_01670 2772231e3db487d288a7d77c0fcf9422 396 ProSitePatterns PS00674 AAA-protein family signature. 277 295 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L04_01670 2772231e3db487d288a7d77c0fcf9422 396 Gene3D G3DSA:3.40.50.300 127 307 6.0E-72 T 23-10-2018 A3L04_01670 2772231e3db487d288a7d77c0fcf9422 396 Gene3D G3DSA:1.10.8.60 308 379 2.3E-30 T 23-10-2018 A3L04_01670 2772231e3db487d288a7d77c0fcf9422 396 SMART SM00382 170 309 1.1E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_01670 2772231e3db487d288a7d77c0fcf9422 396 TIGRFAM TIGR01242 26Sp45: 26S proteasome subunit P45 family 17 378 2.4E-204 T 23-10-2018 IPR005937 26S proteasome regulatory subunit P45-like GO:0005737|GO:0016787|GO:0030163 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L04_01670 2772231e3db487d288a7d77c0fcf9422 396 Hamap MF_00553 Proteasome-activating nucleotidase [pan]. 1 395 47.376 T 23-10-2018 IPR023501 Proteasome-activating nucleotidase PAN A3L04_01670 2772231e3db487d288a7d77c0fcf9422 396 Gene3D G3DSA:2.40.50.140 23 126 8.8E-27 T 23-10-2018 A3L04_01670 2772231e3db487d288a7d77c0fcf9422 396 SUPERFAMILY SSF52540 132 385 9.85E-73 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_06765 ccec1b04f1da0d3eb77fc1df797c8020 170 SUPERFAMILY SSF54814 39 96 1.77E-8 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L04_06765 ccec1b04f1da0d3eb77fc1df797c8020 170 SMART SM00322 57 119 1.9E-4 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L04_06765 ccec1b04f1da0d3eb77fc1df797c8020 170 Gene3D G3DSA:3.30.300.20 47 97 9.4E-10 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L04_06765 ccec1b04f1da0d3eb77fc1df797c8020 170 Pfam PF13184 NusA-like KH domain 57 124 9.1E-9 T 23-10-2018 IPR025249 KH domain, NusA-like GO:0003723 A3L04_05830 08d0571a792d738a6c462e1e7a5b1001 280 Pfam PF00583 Acetyltransferase (GNAT) family 50 144 5.6E-16 T 23-10-2018 IPR000182 GNAT domain A3L04_05830 08d0571a792d738a6c462e1e7a5b1001 280 SUPERFAMILY SSF55729 2 190 9.16E-24 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L04_05830 08d0571a792d738a6c462e1e7a5b1001 280 Gene3D G3DSA:3.40.630.30 1 163 5.3E-23 T 23-10-2018 A3L04_10330 06f263c53975298fba83cb80f037a7a7 429 Gene3D G3DSA:1.10.287.950 108 416 3.4E-64 T 23-10-2018 A3L04_10330 06f263c53975298fba83cb80f037a7a7 429 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 239 266 1.2E-22 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A3L04_10330 06f263c53975298fba83cb80f037a7a7 429 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 268 297 1.2E-22 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A3L04_10330 06f263c53975298fba83cb80f037a7a7 429 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 162 191 1.2E-22 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A3L04_10330 06f263c53975298fba83cb80f037a7a7 429 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 202 352 6.1E-38 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A3L04_10330 06f263c53975298fba83cb80f037a7a7 429 SUPERFAMILY SSF58104 119 416 4.32E-60 T 23-10-2018 A3L04_10330 06f263c53975298fba83cb80f037a7a7 429 SMART SM00283 120 402 7.4E-52 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A3L04_02600 24526e543c850067f5bcc6f85f3edb1b 427 Gene3D G3DSA:3.40.50.720 1 216 1.4E-80 T 23-10-2018 A3L04_02600 24526e543c850067f5bcc6f85f3edb1b 427 SUPERFAMILY SSF52413 303 418 1.57E-32 T 23-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 A3L04_02600 24526e543c850067f5bcc6f85f3edb1b 427 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 410 6.9E-147 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L04_02600 24526e543c850067f5bcc6f85f3edb1b 427 Gene3D G3DSA:3.40.50.720 217 427 6.4E-79 T 23-10-2018 A3L04_02600 24526e543c850067f5bcc6f85f3edb1b 427 SMART SM00984 317 415 3.9E-40 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L04_02600 24526e543c850067f5bcc6f85f3edb1b 427 PIRSF PIRSF000124 1 427 6.4E-142 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L04_02600 24526e543c850067f5bcc6f85f3edb1b 427 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 188 9.2E-69 T 23-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L04_02600 24526e543c850067f5bcc6f85f3edb1b 427 SUPERFAMILY SSF51735 1 192 1.53E-58 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_02600 24526e543c850067f5bcc6f85f3edb1b 427 PIRSF PIRSF500134 1 424 3.6E-147 T 23-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 A3L04_02600 24526e543c850067f5bcc6f85f3edb1b 427 SUPERFAMILY SSF48179 202 296 1.7E-32 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A3L04_02600 24526e543c850067f5bcc6f85f3edb1b 427 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 318 412 1.8E-26 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L04_02600 24526e543c850067f5bcc6f85f3edb1b 427 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 202 294 1.3E-38 T 23-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 Gene3D G3DSA:3.40.50.300 543 625 1.1E-16 T 23-10-2018 A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 Gene3D G3DSA:3.40.50.300 319 499 1.6E-30 T 23-10-2018 A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 SMART SM00487 81 329 3.6E-21 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 Pfam PF01131 DNA topoisomerase 817 1201 4.2E-89 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 SMART SM00437 908 1164 1.2E-118 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 Pfam PF00270 DEAD/DEAH box helicase 88 223 1.0E-11 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 SMART SM00436 793 881 6.8E-45 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 SMART SM00493 639 792 2.2E-46 T 23-10-2018 IPR006171 TOPRIM domain A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 Pfam PF01751 Toprim domain 641 802 3.0E-28 T 23-10-2018 IPR006171 TOPRIM domain A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1125 1139 1.4E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1031 1047 1.4E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 950 959 1.4E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 852 870 1.4E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 766 779 1.4E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 Gene3D G3DSA:1.10.290.10 918 1042 5.6E-150 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 SMART SM00382 98 327 0.007 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 Gene3D G3DSA:3.40.50.300 64 317 1.8E-84 T 23-10-2018 A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 SUPERFAMILY SSF56712 634 1211 5.1E-150 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 Gene3D G3DSA:2.60.510.20 874 1109 5.6E-150 T 23-10-2018 A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 SUPERFAMILY SSF52540 2 241 4.69E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 Gene3D G3DSA:1.10.460.10 822 1205 5.6E-150 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 Gene3D G3DSA:3.40.50.140 627 816 5.6E-30 T 23-10-2018 A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 TIGRFAM TIGR01054 rgy: reverse gyrase 2 1209 0.0 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 SUPERFAMILY SSF52540 324 622 3.36E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09815 82ad3e50e7cd47a451af03f8baaad887 1215 Hamap MF_01125 Reverse gyrase [rgy]. 1 1212 68.473 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 A3L04_02390 8fcd0b190b32238043ca73ad86852006 102 Pfam PF01910 Thiamine-binding protein 6 94 8.9E-34 T 23-10-2018 IPR002767 Thiamine-binding protein A3L04_02390 8fcd0b190b32238043ca73ad86852006 102 Gene3D G3DSA:3.30.70.930 2 98 2.7E-36 T 23-10-2018 IPR029756 MTH1187/YkoF-like A3L04_02390 8fcd0b190b32238043ca73ad86852006 102 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 3 98 9.0E-32 T 23-10-2018 IPR002767 Thiamine-binding protein A3L04_02390 8fcd0b190b32238043ca73ad86852006 102 SUPERFAMILY SSF89957 1 98 7.06E-32 T 23-10-2018 IPR029756 MTH1187/YkoF-like A3L04_10010 1041327fcf8b2d536559a927395d1e1a 646 Gene3D G3DSA:3.30.70.20 580 640 4.8E-11 T 23-10-2018 A3L04_10010 1041327fcf8b2d536559a927395d1e1a 646 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 623 634 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_10010 1041327fcf8b2d536559a927395d1e1a 646 SUPERFAMILY SSF52922 239 353 4.04E-7 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L04_10010 1041327fcf8b2d536559a927395d1e1a 646 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 28 217 5.3E-17 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L04_10010 1041327fcf8b2d536559a927395d1e1a 646 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 16 638 2.4E-279 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A3L04_10010 1041327fcf8b2d536559a927395d1e1a 646 PIRSF PIRSF006439 5 645 3.5E-264 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A3L04_10010 1041327fcf8b2d536559a927395d1e1a 646 SUPERFAMILY SSF52518 14 250 9.94E-60 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L04_10010 1041327fcf8b2d536559a927395d1e1a 646 SUPERFAMILY SSF52518 378 601 6.48E-32 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L04_10010 1041327fcf8b2d536559a927395d1e1a 646 Gene3D G3DSA:3.40.50.970 8 196 3.3E-54 T 23-10-2018 A3L04_10010 1041327fcf8b2d536559a927395d1e1a 646 Gene3D G3DSA:3.40.50.970 386 571 1.1E-22 T 23-10-2018 A3L04_10010 1041327fcf8b2d536559a927395d1e1a 646 Pfam PF12838 4Fe-4S dicluster domain 591 637 5.3E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L04_10010 1041327fcf8b2d536559a927395d1e1a 646 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 408 562 5.9E-30 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L04_10010 1041327fcf8b2d536559a927395d1e1a 646 SUPERFAMILY SSF54862 582 642 2.21E-13 T 23-10-2018 A3L04_04040 2210b102a5a0ddfb58bda1943db50067 443 SUPERFAMILY SSF52540 97 297 1.72E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_04040 2210b102a5a0ddfb58bda1943db50067 443 SUPERFAMILY SSF47446 297 430 6.54E-42 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L04_04040 2210b102a5a0ddfb58bda1943db50067 443 SMART SM00382 99 230 7.1E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_04040 2210b102a5a0ddfb58bda1943db50067 443 SMART SM00963 2 87 2.3E-25 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L04_04040 2210b102a5a0ddfb58bda1943db50067 443 SMART SM00962 100 295 1.1E-102 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L04_04040 2210b102a5a0ddfb58bda1943db50067 443 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 438 38.003 T 23-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 A3L04_04040 2210b102a5a0ddfb58bda1943db50067 443 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 5.6E-20 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L04_04040 2210b102a5a0ddfb58bda1943db50067 443 Pfam PF02978 Signal peptide binding domain 327 425 4.6E-33 T 23-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L04_04040 2210b102a5a0ddfb58bda1943db50067 443 SUPERFAMILY SSF47364 1 94 2.09E-23 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 A3L04_04040 2210b102a5a0ddfb58bda1943db50067 443 Pfam PF00448 SRP54-type protein, GTPase domain 100 295 5.2E-77 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L04_04040 2210b102a5a0ddfb58bda1943db50067 443 Gene3D G3DSA:1.20.120.140 6 305 8.5E-124 T 23-10-2018 A3L04_04040 2210b102a5a0ddfb58bda1943db50067 443 Gene3D G3DSA:3.40.50.300 91 284 8.5E-124 T 23-10-2018 A3L04_04040 2210b102a5a0ddfb58bda1943db50067 443 Gene3D G3DSA:1.10.260.30 310 443 1.5E-51 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L04_04040 2210b102a5a0ddfb58bda1943db50067 443 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 268 281 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L04_00115 b75e09bc72805c29f37f92916ba0e56c 154 SUPERFAMILY SSF55282 8 150 2.62E-46 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_00115 b75e09bc72805c29f37f92916ba0e56c 154 Gene3D G3DSA:3.30.1440.10 3 153 1.7E-49 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_00115 b75e09bc72805c29f37f92916ba0e56c 154 Pfam PF01877 RNA binding 9 132 1.3E-41 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 A3L04_10445 aa51a5a38c7ec8300ec14e577c6d78e9 343 SUPERFAMILY SSF48452 26 180 4.14E-10 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L04_10445 aa51a5a38c7ec8300ec14e577c6d78e9 343 Gene3D G3DSA:1.25.40.10 1 343 3.6E-61 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L04_10445 aa51a5a38c7ec8300ec14e577c6d78e9 343 SMART SM00028 65 98 0.0049 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L04_00960 f143631f82cc28c317e50f25f62df0bd 248 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 242 5.8E-22 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L04_00960 f143631f82cc28c317e50f25f62df0bd 248 Gene3D G3DSA:1.10.3720.10 5 247 5.9E-67 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_00960 f143631f82cc28c317e50f25f62df0bd 248 SUPERFAMILY SSF161098 6 241 9.29E-49 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_01590 a6a0c22dca114235a69048ceea5ecfa5 316 Gene3D G3DSA:1.25.40.10 69 227 6.2E-15 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L04_01590 a6a0c22dca114235a69048ceea5ecfa5 316 SUPERFAMILY SSF48452 85 199 6.64E-12 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L04_01590 a6a0c22dca114235a69048ceea5ecfa5 316 SMART SM00028 119 152 0.033 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L04_01590 a6a0c22dca114235a69048ceea5ecfa5 316 SMART SM00028 82 115 8.5 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L04_01590 a6a0c22dca114235a69048ceea5ecfa5 316 Pfam PF10602 26S proteasome subunit RPN7 84 196 9.0E-8 T 23-10-2018 IPR019585 26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 Reactome: R-HSA-8951664 A3L04_01470 7caff8849e26de052f135a708ad124f8 1738 SUPERFAMILY SSF51294 955 1429 4.32E-33 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L04_01470 7caff8849e26de052f135a708ad124f8 1738 TIGRFAM TIGR00354 polC: DNA polymerase II, large subunit DP2 6 967 0.0 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L04_01470 7caff8849e26de052f135a708ad124f8 1738 Gene3D G3DSA:3.10.28.10 1170 1329 2.4E-27 T 23-10-2018 IPR027434 Homing endonuclease A3L04_01470 7caff8849e26de052f135a708ad124f8 1738 SUPERFAMILY SSF55608 1254 1371 5.67E-8 T 23-10-2018 IPR027434 Homing endonuclease A3L04_01470 7caff8849e26de052f135a708ad124f8 1738 PRINTS PR00379 Intein signature 1172 1184 1.2E-6 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_01470 7caff8849e26de052f135a708ad124f8 1738 PRINTS PR00379 Intein signature 1268 1280 1.2E-6 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_01470 7caff8849e26de052f135a708ad124f8 1738 PRINTS PR00379 Intein signature 1038 1051 1.2E-6 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_01470 7caff8849e26de052f135a708ad124f8 1738 PRINTS PR00379 Intein signature 1404 1421 1.2E-6 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_01470 7caff8849e26de052f135a708ad124f8 1738 Pfam PF14528 LAGLIDADG-like domain 1267 1361 6.4E-10 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L04_01470 7caff8849e26de052f135a708ad124f8 1738 Pfam PF03833 DNA polymerase II large subunit DP2 9 954 0.0 T 23-10-2018 IPR016033 DNA polymerase II large subunit DP2, N-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L04_01470 7caff8849e26de052f135a708ad124f8 1738 Pfam PF14890 Intein splicing domain 998 1427 1.3E-24 T 23-10-2018 A3L04_01470 7caff8849e26de052f135a708ad124f8 1738 SMART SM00306 953 1075 3.0E-30 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L04_01470 7caff8849e26de052f135a708ad124f8 1738 Hamap MF_00324 DNA polymerase II large subunit [polC]. 1 1693 403.334 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L04_01470 7caff8849e26de052f135a708ad124f8 1738 Gene3D G3DSA:2.170.16.10 955 1108 5.7E-46 T 23-10-2018 A3L04_01470 7caff8849e26de052f135a708ad124f8 1738 Gene3D G3DSA:2.170.16.10 1359 1428 4.6E-13 T 23-10-2018 A3L04_01470 7caff8849e26de052f135a708ad124f8 1738 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 955 1051 1.7E-15 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L04_05055 3e87f9176aaad78e14fc47e57b951069 115 SUPERFAMILY SSF49367 1 113 3.53E-41 T 23-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 A3L04_05055 3e87f9176aaad78e14fc47e57b951069 115 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 8 114 2.4E-34 T 23-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 A3L04_05055 3e87f9176aaad78e14fc47e57b951069 115 Pfam PF01880 Desulfoferrodoxin 9 111 2.9E-33 T 23-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 A3L04_05055 3e87f9176aaad78e14fc47e57b951069 115 Gene3D G3DSA:2.60.40.730 1 115 5.5E-52 T 23-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 A3L04_08620 a21aa9bc1afc04f156aa1f5bfdc05bab 74 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 5.6E-15 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L04_08620 a21aa9bc1afc04f156aa1f5bfdc05bab 74 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 56 68 5.6E-15 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L04_08620 a21aa9bc1afc04f156aa1f5bfdc05bab 74 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 17 33 5.6E-15 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L04_08620 a21aa9bc1afc04f156aa1f5bfdc05bab 74 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 38 54 5.6E-15 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L04_08620 a21aa9bc1afc04f156aa1f5bfdc05bab 74 Gene3D G3DSA:2.40.50.970 1 74 3.0E-34 T 23-10-2018 IPR037254 HupF/HypC superfamily A3L04_08620 a21aa9bc1afc04f156aa1f5bfdc05bab 74 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 73 1.2E-30 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L04_08620 a21aa9bc1afc04f156aa1f5bfdc05bab 74 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 23-10-2018 IPR019812 Hydrogenase assembly chaperone, conserved site A3L04_08620 a21aa9bc1afc04f156aa1f5bfdc05bab 74 Pfam PF01455 HupF/HypC family 1 65 1.1E-30 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L04_08620 a21aa9bc1afc04f156aa1f5bfdc05bab 74 SUPERFAMILY SSF159127 1 73 3.4E-28 T 23-10-2018 IPR037254 HupF/HypC superfamily A3L04_06590 736d5c88c83ea5d4bdf399ad567f6923 398 Gene3D G3DSA:2.40.30.110 309 383 3.1E-32 T 23-10-2018 A3L04_06590 736d5c88c83ea5d4bdf399ad567f6923 398 PIRSF PIRSF006487 1 398 2.0E-111 T 23-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A3L04_06590 736d5c88c83ea5d4bdf399ad567f6923 398 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 389 44.652 T 23-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A3L04_06590 736d5c88c83ea5d4bdf399ad567f6923 398 Gene3D G3DSA:3.30.70.1400 52 143 1.3E-94 T 23-10-2018 A3L04_06590 736d5c88c83ea5d4bdf399ad567f6923 398 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 2 387 1.1E-98 T 23-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A3L04_06590 736d5c88c83ea5d4bdf399ad567f6923 398 SUPERFAMILY SSF101790 300 392 9.81E-26 T 23-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal A3L04_06590 736d5c88c83ea5d4bdf399ad567f6923 398 Gene3D G3DSA:4.10.1250.10 268 305 8.0E-11 T 23-10-2018 A3L04_06590 736d5c88c83ea5d4bdf399ad567f6923 398 Pfam PF01571 Aminomethyltransferase folate-binding domain 7 287 2.9E-102 T 23-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain A3L04_06590 736d5c88c83ea5d4bdf399ad567f6923 398 Gene3D G3DSA:3.30.1360.120 8 255 1.3E-94 T 23-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 A3L04_06590 736d5c88c83ea5d4bdf399ad567f6923 398 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 292 382 4.1E-26 T 23-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A3L04_06590 736d5c88c83ea5d4bdf399ad567f6923 398 SUPERFAMILY SSF103025 3 307 1.32E-96 T 23-10-2018 A3L04_07070 69c0d51baa4f9dae9e71550c5b47800e 641 Gene3D G3DSA:2.20.25.90 1 57 2.5E-11 T 23-10-2018 A3L04_07070 69c0d51baa4f9dae9e71550c5b47800e 641 Gene3D G3DSA:2.40.40.20 507 639 1.0E-28 T 23-10-2018 A3L04_07070 69c0d51baa4f9dae9e71550c5b47800e 641 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 3 46 2.7E-7 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07070 69c0d51baa4f9dae9e71550c5b47800e 641 SMART SM00926 1 52 1.6E-8 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07070 69c0d51baa4f9dae9e71550c5b47800e 641 Gene3D G3DSA:3.40.228.10 132 504 1.2E-121 T 23-10-2018 A3L04_07070 69c0d51baa4f9dae9e71550c5b47800e 641 SUPERFAMILY SSF50692 517 638 1.2E-31 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L04_07070 69c0d51baa4f9dae9e71550c5b47800e 641 Gene3D G3DSA:3.40.50.740 66 449 1.2E-121 T 23-10-2018 A3L04_07070 69c0d51baa4f9dae9e71550c5b47800e 641 Pfam PF01568 Molydopterin dinucleotide binding domain 525 628 2.6E-21 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A3L04_07070 69c0d51baa4f9dae9e71550c5b47800e 641 Pfam PF00384 Molybdopterin oxidoreductase 55 435 1.2E-49 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07070 69c0d51baa4f9dae9e71550c5b47800e 641 Gene3D G3DSA:3.30.2070.10 406 486 1.2E-121 T 23-10-2018 A3L04_07070 69c0d51baa4f9dae9e71550c5b47800e 641 SUPERFAMILY SSF53706 3 518 1.96E-135 T 23-10-2018 A3L04_07425 4fe9eb2ae2b37cf0ef83e52954f5abc0 425 SUPERFAMILY SSF118215 14 416 2.62E-127 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A3L04_07425 4fe9eb2ae2b37cf0ef83e52954f5abc0 425 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 45 60 - T 23-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site A3L04_07425 4fe9eb2ae2b37cf0ef83e52954f5abc0 425 PRINTS PR00173 Glutamate-aspartate symporter signature 10 30 3.9E-56 T 23-10-2018 A3L04_07425 4fe9eb2ae2b37cf0ef83e52954f5abc0 425 PRINTS PR00173 Glutamate-aspartate symporter signature 201 220 3.9E-56 T 23-10-2018 A3L04_07425 4fe9eb2ae2b37cf0ef83e52954f5abc0 425 PRINTS PR00173 Glutamate-aspartate symporter signature 336 355 3.9E-56 T 23-10-2018 A3L04_07425 4fe9eb2ae2b37cf0ef83e52954f5abc0 425 PRINTS PR00173 Glutamate-aspartate symporter signature 82 107 3.9E-56 T 23-10-2018 A3L04_07425 4fe9eb2ae2b37cf0ef83e52954f5abc0 425 PRINTS PR00173 Glutamate-aspartate symporter signature 301 327 3.9E-56 T 23-10-2018 A3L04_07425 4fe9eb2ae2b37cf0ef83e52954f5abc0 425 PRINTS PR00173 Glutamate-aspartate symporter signature 53 73 3.9E-56 T 23-10-2018 A3L04_07425 4fe9eb2ae2b37cf0ef83e52954f5abc0 425 PRINTS PR00173 Glutamate-aspartate symporter signature 232 251 3.9E-56 T 23-10-2018 A3L04_07425 4fe9eb2ae2b37cf0ef83e52954f5abc0 425 PRINTS PR00173 Glutamate-aspartate symporter signature 363 383 3.9E-56 T 23-10-2018 A3L04_07425 4fe9eb2ae2b37cf0ef83e52954f5abc0 425 Pfam PF00375 Sodium:dicarboxylate symporter family 14 414 2.0E-129 T 23-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A3L04_07425 4fe9eb2ae2b37cf0ef83e52954f5abc0 425 Gene3D G3DSA:1.10.3860.10 1 422 8.1E-171 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A3L04_06915 4713309289e449bd63f84e811ab3895d 419 SUPERFAMILY SSF52540 10 154 5.92E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_06915 4713309289e449bd63f84e811ab3895d 419 SUPERFAMILY SSF46785 191 269 3.89E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_03620 0441bed6ccc8549a39951edb0eec2de1 293 Pfam PF01435 Peptidase family M48 151 290 6.9E-20 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A3L04_03620 0441bed6ccc8549a39951edb0eec2de1 293 Gene3D G3DSA:3.30.2010.10 138 227 8.8E-18 T 23-10-2018 A3L04_09585 9599143cb910915aeee915685f45390c 380 Gene3D G3DSA:3.30.470.20 122 379 1.1E-95 T 23-10-2018 A3L04_09585 9599143cb910915aeee915685f45390c 380 SUPERFAMILY SSF56059 139 380 1.21E-77 T 23-10-2018 A3L04_09585 9599143cb910915aeee915685f45390c 380 PIRSF PIRSF004602 1 380 2.1E-145 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L04_09585 9599143cb910915aeee915685f45390c 380 Pfam PF06973 Domain of unknown function (DUF1297) 189 380 1.0E-81 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L04_09585 9599143cb910915aeee915685f45390c 380 Gene3D G3DSA:3.30.1490.20 152 218 1.1E-95 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L04_09585 9599143cb910915aeee915685f45390c 380 Gene3D G3DSA:3.40.50.20 1 121 3.9E-44 T 23-10-2018 A3L04_09585 9599143cb910915aeee915685f45390c 380 SUPERFAMILY SSF52440 1 133 4.32E-42 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L04_09585 9599143cb910915aeee915685f45390c 380 Pfam PF06849 Protein of unknown function (DUF1246) 21 154 1.3E-42 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L04_03155 29471dd90d686085916100e365385173 273 Pfam PF00398 Ribosomal RNA adenine dimethylase 15 227 1.8E-56 T 23-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm A3L04_03155 29471dd90d686085916100e365385173 273 SUPERFAMILY SSF53335 13 263 6.02E-68 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_03155 29471dd90d686085916100e365385173 273 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 47 74 - T 23-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 A3L04_03155 29471dd90d686085916100e365385173 273 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 16 259 9.0E-81 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A3L04_03155 29471dd90d686085916100e365385173 273 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 15 263 48.126 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A3L04_03155 29471dd90d686085916100e365385173 273 Gene3D G3DSA:1.10.8.100 196 267 2.7E-8 T 23-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 A3L04_03155 29471dd90d686085916100e365385173 273 SMART SM00650 31 194 5.7E-82 T 23-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 A3L04_03155 29471dd90d686085916100e365385173 273 Gene3D G3DSA:3.40.50.150 2 195 2.1E-68 T 23-10-2018 A3L04_10720 91840eac3072907fb0c6fac417521d0d 51 Gene3D G3DSA:1.10.1620.10 2 51 1.8E-18 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily A3L04_10720 91840eac3072907fb0c6fac417521d0d 51 Hamap MF_00629 50S ribosomal protein L39e [rpl39e]. 1 51 19.51 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_10720 91840eac3072907fb0c6fac417521d0d 51 SUPERFAMILY SSF48662 4 50 5.75E-19 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily A3L04_10720 91840eac3072907fb0c6fac417521d0d 51 Pfam PF00832 Ribosomal L39 protein 9 50 1.9E-21 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_10720 91840eac3072907fb0c6fac417521d0d 51 ProSitePatterns PS00051 Ribosomal protein L39e signature. 30 46 - T 23-10-2018 IPR020083 Ribosomal protein L39e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_00105 3fdc03267b1c28b92ba2f09ad3eb88ca 290 SUPERFAMILY SSF63380 2 94 1.18E-14 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L04_00105 3fdc03267b1c28b92ba2f09ad3eb88ca 290 Gene3D G3DSA:3.40.50.80 101 212 3.2E-23 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L04_00105 3fdc03267b1c28b92ba2f09ad3eb88ca 290 SUPERFAMILY SSF52343 90 257 5.47E-18 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L04_00105 3fdc03267b1c28b92ba2f09ad3eb88ca 290 Gene3D G3DSA:2.40.30.10 1 93 2.2E-14 T 23-10-2018 A3L04_00105 3fdc03267b1c28b92ba2f09ad3eb88ca 290 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 222 258 2.3E-12 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L04_00105 3fdc03267b1c28b92ba2f09ad3eb88ca 290 PIRSF PIRSF006816 1 264 1.9E-65 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L04_01050 09ec18362a073f5f8c6e8ee6a91e5f85 317 Pfam PF01867 CRISPR associated protein Cas1 5 271 2.7E-74 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 A3L04_01050 09ec18362a073f5f8c6e8ee6a91e5f85 317 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 4 317 2.2E-126 T 23-10-2018 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype GO:0004520|GO:0043571|GO:0046872 A3L04_01050 09ec18362a073f5f8c6e8ee6a91e5f85 317 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 5 311 2.5E-83 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 A3L04_01050 09ec18362a073f5f8c6e8ee6a91e5f85 317 Gene3D G3DSA:3.100.10.20 1 80 1.1E-27 T 23-10-2018 A3L04_01050 09ec18362a073f5f8c6e8ee6a91e5f85 317 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 302 24.777 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 A3L04_01050 09ec18362a073f5f8c6e8ee6a91e5f85 317 Gene3D G3DSA:1.20.120.920 82 315 5.7E-61 T 23-10-2018 A3L04_03435 4c469ec7abb12febaaff62cf5ab7c0cb 121 SUPERFAMILY SSF50104 5 116 4.08E-39 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L04_03435 4c469ec7abb12febaaff62cf5ab7c0cb 121 SMART SM00739 45 72 3.4E-7 T 23-10-2018 IPR005824 KOW A3L04_03435 4c469ec7abb12febaaff62cf5ab7c0cb 121 ProSitePatterns PS01108 Ribosomal protein L24 signature. 49 66 - T 23-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_03435 4c469ec7abb12febaaff62cf5ab7c0cb 121 TIGRFAM TIGR01080 rplX_A_E: ribosomal protein uL24 5 120 1.8E-60 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03435 4c469ec7abb12febaaff62cf5ab7c0cb 121 Gene3D G3DSA:2.30.30.30 1 121 2.6E-53 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L04_03435 4c469ec7abb12febaaff62cf5ab7c0cb 121 Pfam PF16906 Ribosomal proteins L26 eukaryotic, L24P archaeal 5 119 5.8E-36 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03435 4c469ec7abb12febaaff62cf5ab7c0cb 121 Hamap MF_01326_A 50S ribosomal protein L24 [rplX]. 5 118 31.88 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03435 4c469ec7abb12febaaff62cf5ab7c0cb 121 Pfam PF00467 KOW motif 48 79 6.8E-10 T 23-10-2018 IPR005824 KOW A3L04_08240 79612cca9beeeee70baa79cc8309bb46 440 Gene3D G3DSA:3.30.2290.10 3 209 9.3E-16 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L04_08240 79612cca9beeeee70baa79cc8309bb46 440 SUPERFAMILY SSF111283 3 436 1.96E-94 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L04_08240 79612cca9beeeee70baa79cc8309bb46 440 Pfam PF01523 Putative modulator of DNA gyrase 23 303 1.4E-50 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L04_05935 0cf0fe4266c494850aff7d643ea9bdf2 226 Gene3D G3DSA:3.40.50.1860 4 217 5.1E-92 T 23-10-2018 A3L04_05935 0cf0fe4266c494850aff7d643ea9bdf2 226 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 79 87 - T 23-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L04_05935 0cf0fe4266c494850aff7d643ea9bdf2 226 SUPERFAMILY SSF53681 117 224 1.19E-26 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L04_05935 0cf0fe4266c494850aff7d643ea9bdf2 226 Gene3D G3DSA:3.40.50.1860 105 211 5.1E-92 T 23-10-2018 A3L04_05935 0cf0fe4266c494850aff7d643ea9bdf2 226 SUPERFAMILY SSF53681 1 111 6.54E-38 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L04_05935 0cf0fe4266c494850aff7d643ea9bdf2 226 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 225 9.2E-104 T 23-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 A3L04_05935 0cf0fe4266c494850aff7d643ea9bdf2 226 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 217 1.3E-61 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L04_00360 635ee28d207188e6db99868d6949e24c 448 Gene3D G3DSA:3.90.1150.10 70 444 5.0E-150 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L04_00360 635ee28d207188e6db99868d6949e24c 448 Gene3D G3DSA:3.40.640.10 81 351 5.0E-150 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L04_00360 635ee28d207188e6db99868d6949e24c 448 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 447 48.494 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 A3L04_00360 635ee28d207188e6db99868d6949e24c 448 Pfam PF02347 Glycine cleavage system P-protein 4 444 1.4E-125 T 23-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A3L04_00360 635ee28d207188e6db99868d6949e24c 448 PIRSF PIRSF006815 3 448 2.8E-160 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 A3L04_00360 635ee28d207188e6db99868d6949e24c 448 SUPERFAMILY SSF53383 3 447 8.78E-103 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L04_03005 45bd8bf0ab9ee43ca9a58b796500db94 172 Gene3D G3DSA:3.10.580.10 98 169 1.8E-15 T 23-10-2018 A3L04_03005 45bd8bf0ab9ee43ca9a58b796500db94 172 SMART SM00116 120 168 2.8E-9 T 23-10-2018 IPR000644 CBS domain A3L04_03005 45bd8bf0ab9ee43ca9a58b796500db94 172 SMART SM00116 42 89 0.0021 T 23-10-2018 IPR000644 CBS domain A3L04_03005 45bd8bf0ab9ee43ca9a58b796500db94 172 SUPERFAMILY SSF54631 23 167 3.13E-29 T 23-10-2018 A3L04_03005 45bd8bf0ab9ee43ca9a58b796500db94 172 Gene3D G3DSA:3.10.580.10 1 88 4.6E-13 T 23-10-2018 A3L04_03005 45bd8bf0ab9ee43ca9a58b796500db94 172 Pfam PF00571 CBS domain 113 167 2.3E-13 T 23-10-2018 IPR000644 CBS domain A3L04_03005 45bd8bf0ab9ee43ca9a58b796500db94 172 Pfam PF00571 CBS domain 38 87 2.2E-12 T 23-10-2018 IPR000644 CBS domain A3L04_08185 5473fb5f6386ec22a6deff07c3feb67c 288 Pfam PF00753 Metallo-beta-lactamase superfamily 31 206 9.5E-18 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_08185 5473fb5f6386ec22a6deff07c3feb67c 288 SUPERFAMILY SSF56281 28 230 1.21E-37 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_08185 5473fb5f6386ec22a6deff07c3feb67c 288 Gene3D G3DSA:3.60.15.10 10 253 1.6E-56 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_08185 5473fb5f6386ec22a6deff07c3feb67c 288 SMART SM00849 23 206 3.7E-29 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_05885 88241d4ee972b3451b3ff5d7f82c7953 105 Pfam PF14697 4Fe-4S dicluster domain 47 100 7.8E-11 T 23-10-2018 A3L04_05885 88241d4ee972b3451b3ff5d7f82c7953 105 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 33 104 2.7E-34 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 A3L04_05885 88241d4ee972b3451b3ff5d7f82c7953 105 Gene3D G3DSA:3.30.70.20 35 70 1.9E-6 T 23-10-2018 A3L04_05885 88241d4ee972b3451b3ff5d7f82c7953 105 Gene3D G3DSA:3.30.70.20 71 105 1.5E-9 T 23-10-2018 A3L04_05885 88241d4ee972b3451b3ff5d7f82c7953 105 SUPERFAMILY SSF54862 32 103 3.93E-25 T 23-10-2018 A3L04_05885 88241d4ee972b3451b3ff5d7f82c7953 105 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_03065 92e691dc412befcf21fd6cc2785857dd 93 PIRSF PIRSF028732 1 92 2.1E-39 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 A3L04_03065 92e691dc412befcf21fd6cc2785857dd 93 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 8 92 2.0E-41 T 23-10-2018 A3L04_03065 92e691dc412befcf21fd6cc2785857dd 93 SUPERFAMILY SSF82704 5 91 4.84E-28 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 A3L04_03065 92e691dc412befcf21fd6cc2785857dd 93 Pfam PF01918 Alba 6 68 3.4E-23 T 23-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 A3L04_03065 92e691dc412befcf21fd6cc2785857dd 93 Gene3D G3DSA:3.30.110.20 2 91 5.8E-38 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 A3L04_03065 92e691dc412befcf21fd6cc2785857dd 93 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 1 91 28.61 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 A3L04_03065 92e691dc412befcf21fd6cc2785857dd 93 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 4 90 6.5E-45 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 A3L04_01435 c8b7923abfa5ead64503d7db32d762d1 126 ProDom PD020987 PF0014 UNCHARACTERIZED AF1250 PH0127 MJ0105 MA4414 ARCHAEAL 1 106 9.0E-47 T 23-10-2018 IPR007417 Protein of unknown function DUF473 A3L04_01435 c8b7923abfa5ead64503d7db32d762d1 126 Pfam PF04322 Protein of unknown function (DUF473) 1 115 2.6E-36 T 23-10-2018 IPR007417 Protein of unknown function DUF473 A3L04_02575 34354bd7efe1c5c61705f5eb0440718a 401 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 287 306 - T 23-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A3L04_02575 34354bd7efe1c5c61705f5eb0440718a 401 SUPERFAMILY SSF53659 4 398 1.86E-130 T 23-10-2018 A3L04_02575 34354bd7efe1c5c61705f5eb0440718a 401 Gene3D G3DSA:3.40.718.10 1 401 1.1E-159 T 23-10-2018 A3L04_02575 34354bd7efe1c5c61705f5eb0440718a 401 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 27 394 4.2E-106 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A3L04_02575 34354bd7efe1c5c61705f5eb0440718a 401 SMART SM01329 26 394 2.4E-166 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A3L04_07165 45495219983efc5977a474485b612beb 69 SUPERFAMILY SSF141694 1 61 5.49E-15 T 23-10-2018 A3L04_07165 45495219983efc5977a474485b612beb 69 Pfam PF01954 Protein of unknown function DUF104 1 55 6.3E-18 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 A3L04_07165 45495219983efc5977a474485b612beb 69 Gene3D G3DSA:4.10.1150.10 1 66 7.6E-14 T 23-10-2018 IPR024069 AF2212-like domain superfamily A3L04_08150 4db1facd13287f703f87ef14ef4f4979 390 Hamap MF_01893 tRNA pseudouridine synthase Pus10 [pus10]. 7 381 55.637 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 A3L04_08150 4db1facd13287f703f87ef14ef4f4979 390 SUPERFAMILY SSF55120 267 379 1.01E-13 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L04_08150 4db1facd13287f703f87ef14ef4f4979 390 SMART SM00981 66 158 7.5E-4 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L04_08150 4db1facd13287f703f87ef14ef4f4979 390 Pfam PF02926 THUMP domain 22 158 3.8E-14 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L04_08150 4db1facd13287f703f87ef14ef4f4979 390 Gene3D G3DSA:3.30.70.2510 158 271 3.1E-31 T 23-10-2018 A3L04_08150 4db1facd13287f703f87ef14ef4f4979 390 Gene3D G3DSA:3.30.70.3190 272 380 8.1E-30 T 23-10-2018 A3L04_08150 4db1facd13287f703f87ef14ef4f4979 390 TIGRFAM TIGR01213 pseudo_Pus10arc: tRNA pseudouridine(54/55) synthase 7 381 2.9E-154 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 A3L04_00970 1eb8eef288ef3a2e702d0f4cc507bbb2 237 SUPERFAMILY SSF160945 1 236 4.84E-59 T 23-10-2018 A3L04_00970 1eb8eef288ef3a2e702d0f4cc507bbb2 237 Gene3D G3DSA:3.40.50.10620 1 228 9.5E-99 T 23-10-2018 A3L04_00970 1eb8eef288ef3a2e702d0f4cc507bbb2 237 ProDom PD038575 MJECL12 PLASMID PH0156 1 232 3.0E-40 T 23-10-2018 IPR024508 Protein of unknown function DUF3226 A3L04_00970 1eb8eef288ef3a2e702d0f4cc507bbb2 237 Gene3D G3DSA:1.10.3490.10 133 225 9.5E-99 T 23-10-2018 A3L04_00970 1eb8eef288ef3a2e702d0f4cc507bbb2 237 Pfam PF11536 Protein of unknown function (DUF3226) 3 235 5.7E-66 T 23-10-2018 IPR024508 Protein of unknown function DUF3226 A3L04_05955 8059c3db766272428f9f52e142c1ab40 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 35 53 3.2E-18 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L04_05955 8059c3db766272428f9f52e142c1ab40 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 57 81 3.2E-18 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L04_05955 8059c3db766272428f9f52e142c1ab40 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 195 209 3.2E-18 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L04_05955 8059c3db766272428f9f52e142c1ab40 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 107 129 3.2E-18 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L04_05955 8059c3db766272428f9f52e142c1ab40 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 11 30 3.2E-18 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L04_05955 8059c3db766272428f9f52e142c1ab40 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 233 249 3.2E-18 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L04_05955 8059c3db766272428f9f52e142c1ab40 249 TIGRFAM TIGR00590 pcna: proliferating cell nuclear antigen (pcna) 3 249 1.4E-39 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L04_05955 8059c3db766272428f9f52e142c1ab40 249 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 126 245 9.0E-11 T 23-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L04_05955 8059c3db766272428f9f52e142c1ab40 249 SUPERFAMILY SSF55979 125 247 2.32E-31 T 23-10-2018 A3L04_05955 8059c3db766272428f9f52e142c1ab40 249 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 3 96 1.3E-18 T 23-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L04_05955 8059c3db766272428f9f52e142c1ab40 249 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 35 58 - T 23-10-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L04_05955 8059c3db766272428f9f52e142c1ab40 249 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 3 247 33.719 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L04_05955 8059c3db766272428f9f52e142c1ab40 249 Gene3D G3DSA:3.70.10.10 2 242 4.9E-78 T 23-10-2018 A3L04_05955 8059c3db766272428f9f52e142c1ab40 249 SUPERFAMILY SSF55979 3 126 6.77E-33 T 23-10-2018 A3L04_04725 d34e2f2f67a898ed21bbdd5bd92017ad 442 Gene3D G3DSA:3.30.2290.10 1 206 7.6E-23 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L04_04725 d34e2f2f67a898ed21bbdd5bd92017ad 442 SUPERFAMILY SSF111283 2 439 6.8E-98 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L04_04725 d34e2f2f67a898ed21bbdd5bd92017ad 442 Pfam PF01523 Putative modulator of DNA gyrase 15 304 3.7E-48 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L04_07160 db794ae28c341748ede81af91d3cc5ed 307 Gene3D G3DSA:3.30.300.10 190 307 4.8E-54 T 23-10-2018 A3L04_07160 db794ae28c341748ede81af91d3cc5ed 307 SUPERFAMILY SSF52402 2 224 6.84E-55 T 23-10-2018 A3L04_07160 db794ae28c341748ede81af91d3cc5ed 307 SUPERFAMILY SSF54810 189 307 6.8E-45 T 23-10-2018 A3L04_07160 db794ae28c341748ede81af91d3cc5ed 307 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 4 307 2.9E-153 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A3L04_07160 db794ae28c341748ede81af91d3cc5ed 307 Hamap MF_00345 GMP synthase [glutamine-hydrolyzing] subunit B [guaAB]. 1 307 46.535 T 23-10-2018 IPR026598 GMP synthase subunit B KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 A3L04_07160 db794ae28c341748ede81af91d3cc5ed 307 Gene3D G3DSA:3.40.50.620 2 189 1.2E-77 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_07160 db794ae28c341748ede81af91d3cc5ed 307 Pfam PF02540 NAD synthase 157 186 6.3E-5 T 23-10-2018 IPR022310 NAD/GMP synthase A3L04_07160 db794ae28c341748ede81af91d3cc5ed 307 Pfam PF02540 NAD synthase 4 85 2.7E-7 T 23-10-2018 IPR022310 NAD/GMP synthase A3L04_07160 db794ae28c341748ede81af91d3cc5ed 307 Pfam PF00958 GMP synthase C terminal domain 218 306 1.6E-34 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A3L04_03770 287385a5504fda192dc05450dae1c302 336 Pfam PF00682 HMGL-like 1 230 1.9E-49 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A3L04_03770 287385a5504fda192dc05450dae1c302 336 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 160 173 - T 23-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A3L04_03770 287385a5504fda192dc05450dae1c302 336 Gene3D G3DSA:3.20.20.70 1 236 3.0E-67 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_03770 287385a5504fda192dc05450dae1c302 336 TIGRFAM TIGR02146 LysS_fung_arch: homocitrate synthase 1 317 7.4E-139 T 23-10-2018 IPR011872 Homocitrate synthase, fungi/archaea GO:0004410|GO:0019752|GO:0019878|GO:0046912 KEGG: 00300+2.3.3.14|KEGG: 00620+2.3.3.14|MetaCyc: PWY-3081|MetaCyc: PWY-7710 A3L04_03770 287385a5504fda192dc05450dae1c302 336 Gene3D G3DSA:1.10.238.260 237 335 1.1E-19 T 23-10-2018 A3L04_03770 287385a5504fda192dc05450dae1c302 336 SUPERFAMILY SSF51569 1 248 1.01E-62 T 23-10-2018 A3L04_03115 5eb6fba6f197b6c79b86759a8c0072d3 87 Pfam PF01247 Ribosomal protein L35Ae 3 86 9.4E-23 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03115 5eb6fba6f197b6c79b86759a8c0072d3 87 Gene3D G3DSA:2.40.10.190 1 87 8.4E-33 T 23-10-2018 IPR038661 Ribosomal protein L35A superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03115 5eb6fba6f197b6c79b86759a8c0072d3 87 ProSitePatterns PS01105 Ribosomal protein L35Ae signature. 55 76 - T 23-10-2018 IPR018266 Ribosomal protein L35Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03115 5eb6fba6f197b6c79b86759a8c0072d3 87 ProDom PD012670 RIBOSOMAL L35A 60S RIBONUCLEOPROTEIN L35A L35AE 50S RNA-BINDING TRNA-BINDING SEQUENCE 3 86 2.0E-41 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03115 5eb6fba6f197b6c79b86759a8c0072d3 87 Hamap MF_00573 50S ribosomal protein L35Ae [rpl35ae]. 3 87 26.227 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03115 5eb6fba6f197b6c79b86759a8c0072d3 87 SUPERFAMILY SSF50447 2 86 6.53E-27 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L04_09535 a877761877aa05cc6d2971b6def4e10b 333 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 2 329 38.402 T 23-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L04_09535 a877761877aa05cc6d2971b6def4e10b 333 Gene3D G3DSA:3.30.1330.10 2 164 3.4E-53 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L04_09535 a877761877aa05cc6d2971b6def4e10b 333 SUPERFAMILY SSF56042 165 326 1.02E-43 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L04_09535 a877761877aa05cc6d2971b6def4e10b 333 Pfam PF02769 AIR synthase related protein, C-terminal domain 170 326 3.9E-27 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L04_09535 a877761877aa05cc6d2971b6def4e10b 333 SUPERFAMILY SSF55326 2 164 3.14E-41 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L04_09535 a877761877aa05cc6d2971b6def4e10b 333 Pfam PF00586 AIR synthase related protein, N-terminal domain 56 158 2.7E-19 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L04_09535 a877761877aa05cc6d2971b6def4e10b 333 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 2 320 2.2E-129 T 23-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L04_09535 a877761877aa05cc6d2971b6def4e10b 333 Gene3D G3DSA:3.90.650.10 165 332 1.6E-50 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L04_08380 e64678ff6edff4f40d0be501899d7a2f 422 SUPERFAMILY SSF53448 2 217 3.42E-35 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_08380 e64678ff6edff4f40d0be501899d7a2f 422 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 291 313 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A3L04_08380 e64678ff6edff4f40d0be501899d7a2f 422 Pfam PF12804 MobA-like NTP transferase domain 3 104 5.6E-17 T 23-10-2018 IPR025877 MobA-like NTP transferase A3L04_08380 e64678ff6edff4f40d0be501899d7a2f 422 Pfam PF01066 CDP-alcohol phosphatidyltransferase 251 313 6.9E-13 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A3L04_08380 e64678ff6edff4f40d0be501899d7a2f 422 Gene3D G3DSA:1.20.120.1760 226 417 7.6E-57 T 23-10-2018 A3L04_08380 e64678ff6edff4f40d0be501899d7a2f 422 Gene3D G3DSA:3.90.550.10 1 216 3.4E-59 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_04000 523a9212970df11f92c78355a817c9b6 302 Gene3D G3DSA:1.10.4200.10 25 293 5.8E-61 T 23-10-2018 A3L04_04000 523a9212970df11f92c78355a817c9b6 302 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 8 286 7.4E-50 T 23-10-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 A3L04_06510 60fb6eed54f8a1e7eaf03a193a03c3dd 67 Gene3D G3DSA:1.10.10.10 5 65 2.9E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_06510 60fb6eed54f8a1e7eaf03a193a03c3dd 67 SUPERFAMILY SSF46785 6 54 1.37E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_06510 60fb6eed54f8a1e7eaf03a193a03c3dd 67 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 6 50 1.4E-4 T 23-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 A3L04_04455 e73162ad89ab7f44722aa5a549c8e1d1 378 Gene3D G3DSA:3.40.50.2000 183 347 2.4E-137 T 23-10-2018 A3L04_04455 e73162ad89ab7f44722aa5a549c8e1d1 378 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 4 361 8.3E-133 T 23-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 A3L04_04455 e73162ad89ab7f44722aa5a549c8e1d1 378 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 26 360 1.3E-118 T 23-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A3L04_04455 e73162ad89ab7f44722aa5a549c8e1d1 378 Gene3D G3DSA:3.40.50.2000 5 357 2.4E-137 T 23-10-2018 A3L04_04455 e73162ad89ab7f44722aa5a549c8e1d1 378 SUPERFAMILY SSF53756 4 364 2.15E-119 T 23-10-2018 A3L04_01515 bd7c14a82db160cfbb5d8395dcb2c415 323 Pfam PF12679 ABC-2 family transporter protein 4 322 1.1E-38 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A3L04_10180 503a5b23b2f3340a580ece7b08fd7163 227 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 227 26.263 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A3L04_10180 503a5b23b2f3340a580ece7b08fd7163 227 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 4 223 4.0E-44 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A3L04_10180 503a5b23b2f3340a580ece7b08fd7163 227 Pfam PF02654 Cobalamin-5-phosphate synthase 7 221 1.4E-38 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A3L04_05490 c966e34275f9037d0f61092f08cd9123 198 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 15 198 29.609 T 23-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 A3L04_05490 c966e34275f9037d0f61092f08cd9123 198 Gene3D G3DSA:3.30.1960.10 6 198 1.3E-72 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L04_05490 c966e34275f9037d0f61092f08cd9123 198 Pfam PF02676 Methyltransferase TYW3 18 198 1.7E-49 T 23-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L04_05490 c966e34275f9037d0f61092f08cd9123 198 SUPERFAMILY SSF111278 13 198 2.88E-61 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L04_03650 ee1f475908dc7f61fb556c4cd6e51dba 376 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 7 375 3.3E-136 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L04_03650 ee1f475908dc7f61fb556c4cd6e51dba 376 Gene3D G3DSA:3.40.50.1980 249 320 8.2E-21 T 23-10-2018 A3L04_03650 ee1f475908dc7f61fb556c4cd6e51dba 376 Pfam PF00815 Histidinol dehydrogenase 255 375 3.3E-39 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L04_03650 ee1f475908dc7f61fb556c4cd6e51dba 376 Pfam PF00815 Histidinol dehydrogenase 3 248 1.6E-95 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L04_03650 ee1f475908dc7f61fb556c4cd6e51dba 376 SUPERFAMILY SSF53720 5 375 5.89E-59 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A3L04_03650 ee1f475908dc7f61fb556c4cd6e51dba 376 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 376 36.755 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L04_03650 ee1f475908dc7f61fb556c4cd6e51dba 376 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 198 230 - T 23-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 A3L04_03650 ee1f475908dc7f61fb556c4cd6e51dba 376 Gene3D G3DSA:3.40.50.1980 1 211 1.2E-74 T 23-10-2018 A3L04_03650 ee1f475908dc7f61fb556c4cd6e51dba 376 PRINTS PR00083 Histidinol dehydrogenase signature 220 239 1.8E-86 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L04_03650 ee1f475908dc7f61fb556c4cd6e51dba 376 PRINTS PR00083 Histidinol dehydrogenase signature 7 31 1.8E-86 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L04_03650 ee1f475908dc7f61fb556c4cd6e51dba 376 PRINTS PR00083 Histidinol dehydrogenase signature 269 294 1.8E-86 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L04_03650 ee1f475908dc7f61fb556c4cd6e51dba 376 PRINTS PR00083 Histidinol dehydrogenase signature 310 328 1.8E-86 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L04_03650 ee1f475908dc7f61fb556c4cd6e51dba 376 PRINTS PR00083 Histidinol dehydrogenase signature 169 194 1.8E-86 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L04_03650 ee1f475908dc7f61fb556c4cd6e51dba 376 PRINTS PR00083 Histidinol dehydrogenase signature 198 219 1.8E-86 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L04_03650 ee1f475908dc7f61fb556c4cd6e51dba 376 PRINTS PR00083 Histidinol dehydrogenase signature 140 166 1.8E-86 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L04_03650 ee1f475908dc7f61fb556c4cd6e51dba 376 PRINTS PR00083 Histidinol dehydrogenase signature 106 132 1.8E-86 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L04_00440 ce771ed8024024b345486a34722f6abf 232 Pfam PF01909 Nucleotidyltransferase domain 31 83 9.1E-8 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L04_00440 ce771ed8024024b345486a34722f6abf 232 Gene3D G3DSA:3.30.460.10 22 99 3.4E-6 T 23-10-2018 A3L04_00440 ce771ed8024024b345486a34722f6abf 232 SUPERFAMILY SSF81301 20 69 5.89E-9 T 23-10-2018 A3L04_00440 ce771ed8024024b345486a34722f6abf 232 PIRSF PIRSF005928 10 232 1.5E-109 T 23-10-2018 IPR009185 Predicted nucleotidyltransferase A3L04_03390 bedaa675a7f137bf4fbdbd2a4dae26fb 239 Gene3D G3DSA:2.30.30.30 85 162 2.7E-31 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L04_03390 bedaa675a7f137bf4fbdbd2a4dae26fb 239 SMART SM01383 11 85 3.4E-29 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_03390 bedaa675a7f137bf4fbdbd2a4dae26fb 239 Hamap MF_01320_A 50S ribosomal protein L2 [rplB]. 1 238 42.898 T 23-10-2018 IPR023672 Ribosomal protein L2, archaeal-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03390 bedaa675a7f137bf4fbdbd2a4dae26fb 239 PIRSF PIRSF002158 1 239 1.5E-75 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_03390 bedaa675a7f137bf4fbdbd2a4dae26fb 239 Gene3D G3DSA:2.40.50.140 1 81 1.3E-30 T 23-10-2018 A3L04_03390 bedaa675a7f137bf4fbdbd2a4dae26fb 239 Gene3D G3DSA:4.10.950.10 163 239 1.0E-34 T 23-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03390 bedaa675a7f137bf4fbdbd2a4dae26fb 239 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 11 84 5.7E-22 T 23-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_03390 bedaa675a7f137bf4fbdbd2a4dae26fb 239 SMART SM01382 91 223 9.5E-65 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A3L04_03390 bedaa675a7f137bf4fbdbd2a4dae26fb 239 SUPERFAMILY SSF50104 94 237 2.17E-49 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L04_03390 bedaa675a7f137bf4fbdbd2a4dae26fb 239 SUPERFAMILY SSF50249 2 92 1.23E-22 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_03390 bedaa675a7f137bf4fbdbd2a4dae26fb 239 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 93 222 6.6E-44 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A3L04_03755 49083344854e4eeb82447d6307abb861 156 Gene3D G3DSA:3.90.190.10 11 153 3.1E-30 T 23-10-2018 IPR029021 Protein-tyrosine phosphatase-like A3L04_03755 49083344854e4eeb82447d6307abb861 156 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 95 105 - T 23-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 A3L04_03755 49083344854e4eeb82447d6307abb861 156 SUPERFAMILY SSF52799 11 150 1.5E-32 T 23-10-2018 IPR029021 Protein-tyrosine phosphatase-like A3L04_03755 49083344854e4eeb82447d6307abb861 156 Pfam PF00782 Dual specificity phosphatase, catalytic domain 53 149 4.0E-15 T 23-10-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 A3L04_03755 49083344854e4eeb82447d6307abb861 156 SMART SM00404 56 150 1.0E-6 T 23-10-2018 IPR003595 Protein-tyrosine phosphatase, catalytic A3L04_03755 49083344854e4eeb82447d6307abb861 156 SMART SM00195 10 150 3.6E-6 T 23-10-2018 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 A3L04_08585 7ea64f6774a3d6b61c4d3dad219463e3 334 Pfam PF17179 4Fe-4S dicluster domain 228 320 8.0E-24 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L04_08585 7ea64f6774a3d6b61c4d3dad219463e3 334 Gene3D G3DSA:1.10.1060.10 278 333 2.3E-5 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L04_08585 7ea64f6774a3d6b61c4d3dad219463e3 334 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 306 317 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_08585 7ea64f6774a3d6b61c4d3dad219463e3 334 SUPERFAMILY SSF46548 225 331 2.49E-13 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L04_08585 7ea64f6774a3d6b61c4d3dad219463e3 334 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 229 240 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_08030 2d6339ac463005374c57c10d8ed2965d 566 Pfam PF00374 Nickel-dependent hydrogenase 216 285 4.2E-12 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L04_08030 2d6339ac463005374c57c10d8ed2965d 566 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 119 140 - T 23-10-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_08030 2d6339ac463005374c57c10d8ed2965d 566 SUPERFAMILY SSF143243 8 192 1.44E-37 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_08030 2d6339ac463005374c57c10d8ed2965d 566 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 91 155 1.0E-16 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_08030 2d6339ac463005374c57c10d8ed2965d 566 SUPERFAMILY SSF56762 190 535 3.53E-118 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_08030 2d6339ac463005374c57c10d8ed2965d 566 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 466 535 9.9E-16 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_08030 2d6339ac463005374c57c10d8ed2965d 566 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 294 457 6.5E-46 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_08030 2d6339ac463005374c57c10d8ed2965d 566 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 34 159 5.9E-24 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_08030 2d6339ac463005374c57c10d8ed2965d 566 Gene3D G3DSA:3.30.460.80 2 138 2.1E-16 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_08030 2d6339ac463005374c57c10d8ed2965d 566 Gene3D G3DSA:1.10.645.20 179 535 4.5E-130 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_08845 53afc9e42be2c5fcb7761290bd4ef668 615 PIRSF PIRSF006439 1 613 8.1E-222 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A3L04_08845 53afc9e42be2c5fcb7761290bd4ef668 615 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 393 534 4.4E-32 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L04_08845 53afc9e42be2c5fcb7761290bd4ef668 615 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 591 602 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_08845 53afc9e42be2c5fcb7761290bd4ef668 615 SUPERFAMILY SSF52518 356 541 9.97E-38 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L04_08845 53afc9e42be2c5fcb7761290bd4ef668 615 SUPERFAMILY SSF54862 551 613 8.56E-13 T 23-10-2018 A3L04_08845 53afc9e42be2c5fcb7761290bd4ef668 615 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 13 190 9.6E-16 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L04_08845 53afc9e42be2c5fcb7761290bd4ef668 615 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 2 606 4.8E-222 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A3L04_08845 53afc9e42be2c5fcb7761290bd4ef668 615 Pfam PF00037 4Fe-4S binding domain 584 607 1.0E-5 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L04_08845 53afc9e42be2c5fcb7761290bd4ef668 615 SUPERFAMILY SSF52922 227 307 2.92E-7 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L04_08845 53afc9e42be2c5fcb7761290bd4ef668 615 Gene3D G3DSA:3.40.50.970 1 180 3.9E-54 T 23-10-2018 A3L04_08845 53afc9e42be2c5fcb7761290bd4ef668 615 Gene3D G3DSA:3.40.50.970 386 550 5.6E-24 T 23-10-2018 A3L04_08845 53afc9e42be2c5fcb7761290bd4ef668 615 SUPERFAMILY SSF52518 3 235 1.67E-58 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L04_08845 53afc9e42be2c5fcb7761290bd4ef668 615 Gene3D G3DSA:3.30.70.20 554 615 1.2E-9 T 23-10-2018 A3L04_00180 e1d5a2774cb852089901d09d5463766f 205 Gene3D G3DSA:1.10.10.10 2 82 7.0E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_00180 e1d5a2774cb852089901d09d5463766f 205 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 178 8.2E-32 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A3L04_00180 e1d5a2774cb852089901d09d5463766f 205 SUPERFAMILY SSF46785 3 79 5.36E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_00180 e1d5a2774cb852089901d09d5463766f 205 PIRSF PIRSF019345 2 197 1.0E-47 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A3L04_00180 e1d5a2774cb852089901d09d5463766f 205 Gene3D G3DSA:1.10.10.10 83 166 5.1E-13 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_00180 e1d5a2774cb852089901d09d5463766f 205 SUPERFAMILY SSF46785 84 152 1.48E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_00180 e1d5a2774cb852089901d09d5463766f 205 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 153 1.1E-36 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A3L04_08155 f13d99f7b53a9f310f1c43440bbd9467 275 Hamap MF_00231 Translation initiation factor 2 subunit alpha [eif2a]. 3 263 34.882 T 23-10-2018 IPR022964 Translation initiation factor 2, alpha subunit, archaeal A3L04_08155 f13d99f7b53a9f310f1c43440bbd9467 275 SMART SM00316 10 83 4.9E-24 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L04_08155 f13d99f7b53a9f310f1c43440bbd9467 275 SUPERFAMILY SSF116742 85 174 1.57E-23 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L04_08155 f13d99f7b53a9f310f1c43440bbd9467 275 SUPERFAMILY SSF50249 7 87 3.56E-21 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_08155 f13d99f7b53a9f310f1c43440bbd9467 275 Gene3D G3DSA:1.10.150.190 86 171 9.1E-36 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L04_08155 f13d99f7b53a9f310f1c43440bbd9467 275 Gene3D G3DSA:3.30.70.1130 173 262 1.4E-32 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L04_08155 f13d99f7b53a9f310f1c43440bbd9467 275 Pfam PF07541 Eukaryotic translation initiation factor 2 alpha subunit 122 233 6.0E-22 T 23-10-2018 IPR011488 Translation initiation factor 2, alpha subunit GO:0003723|GO:0003743 Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L04_08155 f13d99f7b53a9f310f1c43440bbd9467 275 Pfam PF00575 S1 RNA binding domain 9 83 1.0E-14 T 23-10-2018 IPR003029 S1 domain GO:0003676 A3L04_08155 f13d99f7b53a9f310f1c43440bbd9467 275 SUPERFAMILY SSF110993 176 260 4.32E-22 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L04_08155 f13d99f7b53a9f310f1c43440bbd9467 275 Gene3D G3DSA:2.40.50.140 3 85 1.1E-31 T 23-10-2018 A3L04_08885 0d680b1d9d1cd4a3f12c2c0a99c6a2d9 237 Pfam PF06745 KaiC 8 230 4.7E-47 T 23-10-2018 IPR014774 KaiC-like domain A3L04_08885 0d680b1d9d1cd4a3f12c2c0a99c6a2d9 237 Gene3D G3DSA:3.40.50.300 3 232 3.6E-53 T 23-10-2018 A3L04_08885 0d680b1d9d1cd4a3f12c2c0a99c6a2d9 237 SUPERFAMILY SSF52540 6 229 5.74E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_02045 ad1d48fd57b3f5b675117ef6a25a4b79 254 SUPERFAMILY SSF58104 11 211 8.24E-38 T 23-10-2018 A3L04_02045 ad1d48fd57b3f5b675117ef6a25a4b79 254 Gene3D G3DSA:1.10.287.950 1 245 5.7E-36 T 23-10-2018 A3L04_02045 ad1d48fd57b3f5b675117ef6a25a4b79 254 SMART SM00283 4 244 8.0E-5 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A3L04_02045 ad1d48fd57b3f5b675117ef6a25a4b79 254 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 82 201 1.8E-28 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A3L04_02045 ad1d48fd57b3f5b675117ef6a25a4b79 254 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 99 126 9.0E-18 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A3L04_02045 ad1d48fd57b3f5b675117ef6a25a4b79 254 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 175 204 9.0E-18 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A3L04_02045 ad1d48fd57b3f5b675117ef6a25a4b79 254 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 128 157 9.0E-18 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A3L04_09605 1654d742542db15ffe6d4983d95f9a91 317 PIRSF PIRSF002849 1 314 6.7E-127 T 23-10-2018 A3L04_09605 1654d742542db15ffe6d4983d95f9a91 317 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 36 165 3.4E-64 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A3L04_09605 1654d742542db15ffe6d4983d95f9a91 317 Gene3D G3DSA:3.40.50.300 16 183 2.6E-47 T 23-10-2018 A3L04_09605 1654d742542db15ffe6d4983d95f9a91 317 Gene3D G3DSA:1.10.8.300 200 309 1.5E-30 T 23-10-2018 A3L04_09605 1654d742542db15ffe6d4983d95f9a91 317 SUPERFAMILY SSF52540 10 284 3.25E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_08955 ded58af893137f9cacb1dc91da164989 292 Pfam PF00970 Oxidoreductase FAD-binding domain 34 111 3.3E-8 T 23-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A3L04_08955 ded58af893137f9cacb1dc91da164989 292 Gene3D G3DSA:3.40.50.80 117 248 7.1E-23 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L04_08955 ded58af893137f9cacb1dc91da164989 292 PRINTS PR00410 Phenol hydroxylase reductase family signature 50 62 1.3E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L04_08955 ded58af893137f9cacb1dc91da164989 292 PRINTS PR00410 Phenol hydroxylase reductase family signature 124 143 1.3E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L04_08955 ded58af893137f9cacb1dc91da164989 292 PRINTS PR00410 Phenol hydroxylase reductase family signature 216 224 1.3E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L04_08955 ded58af893137f9cacb1dc91da164989 292 Pfam PF00175 Oxidoreductase NAD-binding domain 125 229 3.3E-13 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A3L04_08955 ded58af893137f9cacb1dc91da164989 292 SUPERFAMILY SSF52343 108 283 2.1E-32 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L04_08955 ded58af893137f9cacb1dc91da164989 292 Gene3D G3DSA:2.10.240.10 249 285 3.2E-8 T 23-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily A3L04_08955 ded58af893137f9cacb1dc91da164989 292 Gene3D G3DSA:2.40.30.10 14 112 1.2E-20 T 23-10-2018 A3L04_08955 ded58af893137f9cacb1dc91da164989 292 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 248 284 2.0E-13 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L04_08955 ded58af893137f9cacb1dc91da164989 292 SUPERFAMILY SSF63380 11 116 2.51E-25 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L04_08955 ded58af893137f9cacb1dc91da164989 292 PIRSF PIRSF006816 14 291 9.1E-85 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L04_00625 f0bf1a116818308cc0fb2fe47058e1de 522 TIGRFAM TIGR01564 S_layer_MJ: S-layer protein 389 494 7.5E-8 T 23-10-2018 IPR006454 S-layer protein GO:0005618 A3L04_00625 f0bf1a116818308cc0fb2fe47058e1de 522 Pfam PF05124 S-layer like family, C-terminal region 386 495 2.0E-12 T 23-10-2018 IPR022651 S-layer protein, C-terminal A3L04_00625 f0bf1a116818308cc0fb2fe47058e1de 522 Pfam PF16286 Domain of unknown function (DUF4932) 16 240 1.5E-14 T 23-10-2018 IPR032560 Protein of unknown function DUF4932 A3L04_06035 56080a44f4f30b38b95d739ce6678a18 350 Pfam PF01170 Putative RNA methylase family UPF0020 179 342 5.2E-37 T 23-10-2018 IPR000241 Putative RNA methylase domain A3L04_06035 56080a44f4f30b38b95d739ce6678a18 350 SUPERFAMILY SSF143437 18 167 2.27E-16 T 23-10-2018 A3L04_06035 56080a44f4f30b38b95d739ce6678a18 350 SMART SM00981 76 168 4.5E-18 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L04_06035 56080a44f4f30b38b95d739ce6678a18 350 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 208 219 - T 23-10-2018 IPR000241 Putative RNA methylase domain A3L04_06035 56080a44f4f30b38b95d739ce6678a18 350 Gene3D G3DSA:3.30.2130.30 2 175 1.0E-55 T 23-10-2018 A3L04_06035 56080a44f4f30b38b95d739ce6678a18 350 Gene3D G3DSA:3.40.50.150 176 350 7.4E-47 T 23-10-2018 A3L04_06035 56080a44f4f30b38b95d739ce6678a18 350 Pfam PF02926 THUMP domain 40 167 5.1E-26 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L04_06035 56080a44f4f30b38b95d739ce6678a18 350 SUPERFAMILY SSF53335 165 337 1.91E-32 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_02125 7b609a5094bf7f603717927b5f6c9df8 704 Gene3D G3DSA:3.90.650.10 541 704 2.2E-31 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L04_02125 7b609a5094bf7f603717927b5f6c9df8 704 SUPERFAMILY SSF56042 184 402 3.89E-52 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L04_02125 7b609a5094bf7f603717927b5f6c9df8 704 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 704 253.463 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L04_02125 7b609a5094bf7f603717927b5f6c9df8 704 Pfam PF00586 AIR synthase related protein, N-terminal domain 67 172 2.9E-24 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L04_02125 7b609a5094bf7f603717927b5f6c9df8 704 Pfam PF00586 AIR synthase related protein, N-terminal domain 417 533 9.1E-20 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L04_02125 7b609a5094bf7f603717927b5f6c9df8 704 Gene3D G3DSA:3.30.1330.10 27 175 1.1E-120 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L04_02125 7b609a5094bf7f603717927b5f6c9df8 704 PIRSF PIRSF001587 1 704 1.4E-280 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L04_02125 7b609a5094bf7f603717927b5f6c9df8 704 SUPERFAMILY SSF55326 371 534 2.75E-49 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L04_02125 7b609a5094bf7f603717927b5f6c9df8 704 SUPERFAMILY SSF56042 539 703 1.64E-28 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L04_02125 7b609a5094bf7f603717927b5f6c9df8 704 Gene3D G3DSA:3.90.650.10 12 341 1.1E-120 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L04_02125 7b609a5094bf7f603717927b5f6c9df8 704 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 2 703 1.1E-297 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L04_02125 7b609a5094bf7f603717927b5f6c9df8 704 SUPERFAMILY SSF55326 19 178 1.14E-47 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L04_02125 7b609a5094bf7f603717927b5f6c9df8 704 Gene3D G3DSA:3.30.1330.10 364 536 2.2E-55 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L04_02125 7b609a5094bf7f603717927b5f6c9df8 704 Pfam PF02769 AIR synthase related protein, C-terminal domain 544 662 3.9E-11 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L04_02125 7b609a5094bf7f603717927b5f6c9df8 704 Pfam PF02769 AIR synthase related protein, C-terminal domain 185 340 1.9E-35 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L04_07340 d19552d16ffdb2b5a1159291b490f0aa 216 SUPERFAMILY SSF89550 1 212 3.14E-39 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L04_07340 d19552d16ffdb2b5a1159291b490f0aa 216 Pfam PF02811 PHP domain 3 77 1.0E-9 T 23-10-2018 IPR004013 PHP domain GO:0003824 A3L04_07340 d19552d16ffdb2b5a1159291b490f0aa 216 SMART SM00481 2 74 2.8E-18 T 23-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A3L04_07340 d19552d16ffdb2b5a1159291b490f0aa 216 Gene3D G3DSA:3.20.20.140 1 215 1.0E-49 T 23-10-2018 A3L04_02655 3f66fbbd56fd07656d0b7b81a04c858a 356 Pfam PF00534 Glycosyl transferases group 1 181 335 1.7E-29 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L04_02655 3f66fbbd56fd07656d0b7b81a04c858a 356 Gene3D G3DSA:3.40.50.2000 17 351 8.5E-54 T 23-10-2018 A3L04_02655 3f66fbbd56fd07656d0b7b81a04c858a 356 Gene3D G3DSA:3.40.50.2000 175 340 8.5E-54 T 23-10-2018 A3L04_02655 3f66fbbd56fd07656d0b7b81a04c858a 356 Pfam PF13439 Glycosyltransferase Family 4 16 175 8.9E-16 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L04_02655 3f66fbbd56fd07656d0b7b81a04c858a 356 SUPERFAMILY SSF53756 13 353 4.55E-67 T 23-10-2018 A3L04_09500 6e03ba287d5c62144984d848dcd3cd6a 294 Pfam PF03595 Voltage-dependent anion channel 7 288 1.1E-57 T 23-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 A3L04_09500 6e03ba287d5c62144984d848dcd3cd6a 294 Gene3D G3DSA:1.50.10.150 88 294 7.5E-28 T 23-10-2018 IPR038665 Voltage-dependent anion channel superfamily A3L04_09500 6e03ba287d5c62144984d848dcd3cd6a 294 Gene3D G3DSA:1.50.10.150 1 87 8.1E-16 T 23-10-2018 IPR038665 Voltage-dependent anion channel superfamily A3L04_10400 26ecf40f6ad44bc433b538ad383b537c 439 SUPERFAMILY SSF55931 96 437 2.45E-122 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A3L04_10400 26ecf40f6ad44bc433b538ad383b537c 439 ProSitePatterns PS00180 Glutamine synthetase signature 1. 48 66 - T 23-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A3L04_10400 26ecf40f6ad44bc433b538ad383b537c 439 SMART SM01230 96 339 1.8E-135 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L04_10400 26ecf40f6ad44bc433b538ad383b537c 439 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 15 90 1.7E-22 T 23-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A3L04_10400 26ecf40f6ad44bc433b538ad383b537c 439 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 222 237 - T 23-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A3L04_10400 26ecf40f6ad44bc433b538ad383b537c 439 Gene3D G3DSA:3.10.20.70 6 98 2.3E-23 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L04_10400 26ecf40f6ad44bc433b538ad383b537c 439 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 11 437 1.1E-181 T 23-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L04_10400 26ecf40f6ad44bc433b538ad383b537c 439 SUPERFAMILY SSF54368 14 95 3.79E-20 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L04_10400 26ecf40f6ad44bc433b538ad383b537c 439 Gene3D G3DSA:3.30.590.10 99 438 7.3E-129 T 23-10-2018 A3L04_10400 26ecf40f6ad44bc433b538ad383b537c 439 Pfam PF00120 Glutamine synthetase, catalytic domain 97 436 2.2E-130 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L04_05385 33d9d3bd824e9c8c234a94d0a5a7acbf 396 Pfam PF01546 Peptidase family M20/M25/M40 77 394 3.5E-38 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A3L04_05385 33d9d3bd824e9c8c234a94d0a5a7acbf 396 SUPERFAMILY SSF53187 1 393 2.88E-60 T 23-10-2018 A3L04_05385 33d9d3bd824e9c8c234a94d0a5a7acbf 396 Gene3D G3DSA:3.30.70.360 188 316 5.5E-78 T 23-10-2018 A3L04_05385 33d9d3bd824e9c8c234a94d0a5a7acbf 396 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 2 389 3.6E-81 T 23-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase A3L04_05385 33d9d3bd824e9c8c234a94d0a5a7acbf 396 SUPERFAMILY SSF55031 190 297 1.64E-18 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A3L04_05385 33d9d3bd824e9c8c234a94d0a5a7acbf 396 Pfam PF07687 Peptidase dimerisation domain 185 295 2.8E-20 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A3L04_05385 33d9d3bd824e9c8c234a94d0a5a7acbf 396 Gene3D G3DSA:3.40.630.10 7 384 5.5E-78 T 23-10-2018 A3L04_10215 5e3c98c13cbc9db0ccd95185df21066e 497 SUPERFAMILY SSF55486 7 497 1.47E-110 T 23-10-2018 A3L04_10215 5e3c98c13cbc9db0ccd95185df21066e 497 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 11 496 4.8E-104 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L04_10215 5e3c98c13cbc9db0ccd95185df21066e 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 248 267 7.0E-89 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L04_10215 5e3c98c13cbc9db0ccd95185df21066e 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 295 311 7.0E-89 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L04_10215 5e3c98c13cbc9db0ccd95185df21066e 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 268 287 7.0E-89 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L04_10215 5e3c98c13cbc9db0ccd95185df21066e 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 404 425 7.0E-89 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L04_10215 5e3c98c13cbc9db0ccd95185df21066e 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 381 398 7.0E-89 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L04_10215 5e3c98c13cbc9db0ccd95185df21066e 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 231 247 7.0E-89 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L04_10215 5e3c98c13cbc9db0ccd95185df21066e 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 335 354 7.0E-89 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L04_10215 5e3c98c13cbc9db0ccd95185df21066e 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 149 169 7.0E-89 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L04_10215 5e3c98c13cbc9db0ccd95185df21066e 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 448 466 7.0E-89 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L04_10215 5e3c98c13cbc9db0ccd95185df21066e 497 PIRSF PIRSF006615 5 497 4.1E-198 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L04_10215 5e3c98c13cbc9db0ccd95185df21066e 497 Gene3D G3DSA:1.10.1370.30 1 497 2.0E-195 T 23-10-2018 A3L04_10080 2f93c1540ed1277828082d38ee92c92a 123 Pfam PF11469 Ribonuclease III 3 119 1.3E-56 T 23-10-2018 IPR021568 Ribonuclease III, archaeal A3L04_10080 2f93c1540ed1277828082d38ee92c92a 123 Gene3D G3DSA:1.10.1520.20 1 123 8.7E-54 T 23-10-2018 IPR038133 Ribonuclease III superfamily, archaeal A3L04_10080 2f93c1540ed1277828082d38ee92c92a 123 SUPERFAMILY SSF69065 2 121 2.88E-54 T 23-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 A3L04_09005 484f4e1fef2ce5b9a3a55b5527cdf2fe 450 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 191 449 3.4E-63 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L04_09005 484f4e1fef2ce5b9a3a55b5527cdf2fe 450 Gene3D G3DSA:3.40.50.150 154 449 4.1E-80 T 23-10-2018 A3L04_09005 484f4e1fef2ce5b9a3a55b5527cdf2fe 450 Pfam PF01029 NusB family 11 133 1.7E-17 T 23-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A3L04_09005 484f4e1fef2ce5b9a3a55b5527cdf2fe 450 Pfam PF01189 16S rRNA methyltransferase RsmB/F 255 447 2.4E-50 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L04_09005 484f4e1fef2ce5b9a3a55b5527cdf2fe 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 237 251 7.6E-22 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_09005 484f4e1fef2ce5b9a3a55b5527cdf2fe 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 266 276 7.6E-22 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_09005 484f4e1fef2ce5b9a3a55b5527cdf2fe 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 331 343 7.6E-22 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_09005 484f4e1fef2ce5b9a3a55b5527cdf2fe 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 432 449 7.6E-22 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_09005 484f4e1fef2ce5b9a3a55b5527cdf2fe 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 381 397 7.6E-22 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_09005 484f4e1fef2ce5b9a3a55b5527cdf2fe 450 SUPERFAMILY SSF53335 148 449 5.77E-71 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_09005 484f4e1fef2ce5b9a3a55b5527cdf2fe 450 Gene3D G3DSA:1.10.940.10 6 151 3.2E-13 T 23-10-2018 IPR035926 NusB-like superfamily A3L04_09005 484f4e1fef2ce5b9a3a55b5527cdf2fe 450 SUPERFAMILY SSF48013 10 163 2.35E-22 T 23-10-2018 IPR035926 NusB-like superfamily A3L04_03865 31b24a5c4ade9c7462acb5de42074716 500 SUPERFAMILY SSF52540 237 484 1.09E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_03865 31b24a5c4ade9c7462acb5de42074716 500 SUPERFAMILY SSF52540 5 227 1.33E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_03865 31b24a5c4ade9c7462acb5de42074716 500 Pfam PF00005 ABC transporter 20 168 3.9E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_03865 31b24a5c4ade9c7462acb5de42074716 500 Pfam PF00005 ABC transporter 273 426 1.0E-15 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_03865 31b24a5c4ade9c7462acb5de42074716 500 ProSitePatterns PS00211 ABC transporters family signature. 398 412 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_03865 31b24a5c4ade9c7462acb5de42074716 500 Gene3D G3DSA:3.40.50.300 245 489 8.0E-46 T 23-10-2018 A3L04_03865 31b24a5c4ade9c7462acb5de42074716 500 SMART SM00382 29 216 6.3E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_03865 31b24a5c4ade9c7462acb5de42074716 500 SMART SM00382 281 482 3.6 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_03865 31b24a5c4ade9c7462acb5de42074716 500 Gene3D G3DSA:3.40.50.300 1 243 4.5E-59 T 23-10-2018 A3L04_10700 4545f0a264e6b390b9e47734d39f31c8 117 Gene3D G3DSA:1.10.287.370 1 117 3.0E-41 T 23-10-2018 IPR009053 Prefoldin A3L04_10700 4545f0a264e6b390b9e47734d39f31c8 117 SUPERFAMILY SSF46579 6 111 1.7E-23 T 23-10-2018 A3L04_10700 4545f0a264e6b390b9e47734d39f31c8 117 Pfam PF01920 Prefoldin subunit 9 111 2.1E-25 T 23-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 A3L04_10700 4545f0a264e6b390b9e47734d39f31c8 117 TIGRFAM TIGR02338 gimC_beta: prefoldin, beta subunit 4 112 3.7E-41 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 A3L04_10700 4545f0a264e6b390b9e47734d39f31c8 117 Hamap MF_00307 Prefoldin subunit beta [pfdB]. 1 117 50.898 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 A3L04_01950 a3dc0fb2bab651da140f9db2d9e47e72 374 SMART SM00228 194 261 4.0E-12 T 23-10-2018 IPR001478 PDZ domain GO:0005515 A3L04_01950 a3dc0fb2bab651da140f9db2d9e47e72 374 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 154 166 2.0E-22 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L04_01950 a3dc0fb2bab651da140f9db2d9e47e72 374 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 102 121 2.0E-22 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L04_01950 a3dc0fb2bab651da140f9db2d9e47e72 374 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 138 153 2.0E-22 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L04_01950 a3dc0fb2bab651da140f9db2d9e47e72 374 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 122 136 2.0E-22 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L04_01950 a3dc0fb2bab651da140f9db2d9e47e72 374 SUPERFAMILY SSF50156 202 291 1.01E-23 T 23-10-2018 IPR036034 PDZ superfamily GO:0005515 A3L04_01950 a3dc0fb2bab651da140f9db2d9e47e72 374 Pfam PF02163 Peptidase family M50 114 340 1.4E-23 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L04_01950 a3dc0fb2bab651da140f9db2d9e47e72 374 Gene3D G3DSA:2.30.42.10 201 288 7.1E-23 T 23-10-2018 A3L04_01950 a3dc0fb2bab651da140f9db2d9e47e72 374 Pfam PF13180 PDZ domain 201 270 3.8E-12 T 23-10-2018 IPR001478 PDZ domain GO:0005515 A3L04_08685 4b1db188a0d08862a2760916fd81a68a 465 SUPERFAMILY SSF51182 191 464 6.07E-69 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L04_08685 4b1db188a0d08862a2760916fd81a68a 465 Pfam PF00483 Nucleotidyl transferase 2 278 1.6E-59 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L04_08685 4b1db188a0d08862a2760916fd81a68a 465 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 3 464 9.5E-160 T 23-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 A3L04_08685 4b1db188a0d08862a2760916fd81a68a 465 Gene3D G3DSA:3.90.550.10 1 346 4.0E-114 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_08685 4b1db188a0d08862a2760916fd81a68a 465 Pfam PF01050 Mannose-6-phosphate isomerase 310 460 4.7E-68 T 23-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 A3L04_08685 4b1db188a0d08862a2760916fd81a68a 465 SUPERFAMILY SSF53448 1 272 5.63E-66 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_08685 4b1db188a0d08862a2760916fd81a68a 465 Gene3D G3DSA:2.60.120.10 348 457 1.4E-19 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L04_07260 40d62a65def5379e500eebc15f0a1d2b 94 Pfam PF05239 PRC-barrel domain 1 86 4.6E-11 T 23-10-2018 IPR027275 PRC-barrel domain A3L04_07260 40d62a65def5379e500eebc15f0a1d2b 94 SUPERFAMILY SSF50346 4 84 1.37E-10 T 23-10-2018 IPR011033 PRC-barrel-like superfamily A3L04_01260 ebe056b7157ea1a9d387a8e82c97c4e7 179 SUPERFAMILY SSF54631 5 133 1.14E-31 T 23-10-2018 A3L04_01260 ebe056b7157ea1a9d387a8e82c97c4e7 179 Gene3D G3DSA:3.10.580.10 3 175 1.2E-42 T 23-10-2018 A3L04_01260 ebe056b7157ea1a9d387a8e82c97c4e7 179 SMART SM00116 79 126 4.5E-8 T 23-10-2018 IPR000644 CBS domain A3L04_01260 ebe056b7157ea1a9d387a8e82c97c4e7 179 SMART SM00116 14 61 2.9E-8 T 23-10-2018 IPR000644 CBS domain A3L04_01260 ebe056b7157ea1a9d387a8e82c97c4e7 179 Pfam PF00571 CBS domain 72 126 1.6E-13 T 23-10-2018 IPR000644 CBS domain A3L04_01260 ebe056b7157ea1a9d387a8e82c97c4e7 179 Pfam PF00571 CBS domain 7 60 2.8E-10 T 23-10-2018 IPR000644 CBS domain A3L04_01335 0436e0329987627dbb41e20b16da55c7 565 Pfam PF04458 Protein of unknown function (DUF505) 1 297 3.4E-71 T 23-10-2018 IPR007548 Protein of unknown function DUF505 A3L04_01335 0436e0329987627dbb41e20b16da55c7 565 Pfam PF04458 Protein of unknown function (DUF505) 303 563 2.5E-79 T 23-10-2018 IPR007548 Protein of unknown function DUF505 A3L04_10340 3d19b76efbae4d71fd01700d0672d0a9 276 Pfam PF01008 Initiation factor 2 subunit family 18 271 6.1E-52 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A3L04_10340 3d19b76efbae4d71fd01700d0672d0a9 276 Gene3D G3DSA:3.40.50.10470 96 276 2.7E-64 T 23-10-2018 A3L04_10340 3d19b76efbae4d71fd01700d0672d0a9 276 SUPERFAMILY SSF100950 5 272 5.12E-70 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L04_10340 3d19b76efbae4d71fd01700d0672d0a9 276 Gene3D G3DSA:1.20.120.420 1 95 1.1E-38 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L04_03145 3a4dac09513dbc43049fbe91d106580c 401 Gene3D G3DSA:3.30.300.280 13 394 1.8E-169 T 23-10-2018 A3L04_03145 3a4dac09513dbc43049fbe91d106580c 401 Gene3D G3DSA:3.30.300.10 27 151 1.8E-169 T 23-10-2018 A3L04_03145 3a4dac09513dbc43049fbe91d106580c 401 Gene3D G3DSA:3.30.300.340 15 283 1.8E-169 T 23-10-2018 A3L04_03145 3a4dac09513dbc43049fbe91d106580c 401 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 18 401 0.0 T 23-10-2018 A3L04_03145 3a4dac09513dbc43049fbe91d106580c 401 Hamap MF_00136 S-adenosylmethionine synthase [mat]. 2 401 52.304 T 23-10-2018 IPR002795 S-adenosylmethionine synthetase, archaea GO:0004478|GO:0005524|GO:0006730 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 A3L04_03145 3a4dac09513dbc43049fbe91d106580c 401 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 3 397 1.1E-179 T 23-10-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 A3L04_04030 157675a3d68a5a76326d554dcc36771a 234 Gene3D G3DSA:3.40.120.10 3 78 4.5E-7 T 23-10-2018 A3L04_04030 157675a3d68a5a76326d554dcc36771a 234 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 6 76 1.7E-6 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_04030 157675a3d68a5a76326d554dcc36771a 234 SUPERFAMILY SSF53738 7 78 6.28E-8 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_04030 157675a3d68a5a76326d554dcc36771a 234 SUPERFAMILY SSF53738 132 208 3.18E-8 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L04_05950 80786ad2dc2f434269b5ee9bfb537724 187 Gene3D G3DSA:1.20.58.1030 1 113 5.2E-42 T 23-10-2018 A3L04_05950 80786ad2dc2f434269b5ee9bfb537724 187 PIRSF PIRSF019075 1 187 2.4E-81 T 23-10-2018 IPR016745 Uncharacterised conserved protein UCP019075 A3L04_05950 80786ad2dc2f434269b5ee9bfb537724 187 Gene3D G3DSA:3.40.5.50 135 187 1.7E-20 T 23-10-2018 A3L04_04575 f3e2f9eea0067e0b71c0e0c06863cf23 420 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 182 416 1.3E-78 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L04_04575 f3e2f9eea0067e0b71c0e0c06863cf23 420 SUPERFAMILY SSF53223 4 184 3.52E-68 T 23-10-2018 A3L04_04575 f3e2f9eea0067e0b71c0e0c06863cf23 420 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 34 161 3.1E-53 T 23-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L04_04575 f3e2f9eea0067e0b71c0e0c06863cf23 420 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 216 236 2.6E-33 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L04_04575 f3e2f9eea0067e0b71c0e0c06863cf23 420 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 173 195 2.6E-33 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L04_04575 f3e2f9eea0067e0b71c0e0c06863cf23 420 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 91 105 2.6E-33 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L04_04575 f3e2f9eea0067e0b71c0e0c06863cf23 420 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 344 355 2.6E-33 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L04_04575 f3e2f9eea0067e0b71c0e0c06863cf23 420 Gene3D G3DSA:3.40.50.720 182 419 1.6E-98 T 23-10-2018 A3L04_04575 f3e2f9eea0067e0b71c0e0c06863cf23 420 PIRSF PIRSF000185 1 419 1.8E-174 T 23-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 A3L04_04575 f3e2f9eea0067e0b71c0e0c06863cf23 420 SMART SM00839 184 416 3.4E-103 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L04_04575 f3e2f9eea0067e0b71c0e0c06863cf23 420 SUPERFAMILY SSF51735 182 418 1.48E-83 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_04575 f3e2f9eea0067e0b71c0e0c06863cf23 420 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 99 112 - T 23-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L04_04575 f3e2f9eea0067e0b71c0e0c06863cf23 420 Gene3D G3DSA:3.40.50.10860 36 181 1.3E-67 T 23-10-2018 A3L04_08970 25f2c7dbb763c01b8ff353ad18646b65 95 ProDom PD029791 ORF 3'REGION GAP PF1875 PF0899 PH1831 B PHS036 1 95 1.0E-36 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L04_08970 25f2c7dbb763c01b8ff353ad18646b65 95 Gene3D G3DSA:3.30.2320.10 1 95 2.0E-39 T 23-10-2018 A3L04_08970 25f2c7dbb763c01b8ff353ad18646b65 95 Pfam PF08967 Domain of unknown function (DUF1884) 4 95 3.2E-39 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L04_08970 25f2c7dbb763c01b8ff353ad18646b65 95 SUPERFAMILY SSF111057 3 95 5.23E-35 T 23-10-2018 IPR036216 Hypothetical protein UCP004604 superfamily A3L04_08970 25f2c7dbb763c01b8ff353ad18646b65 95 PIRSF PIRSF004604 1 95 2.1E-29 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L04_10560 4a224ed04de5d841185998fd9fc0e4f5 421 Pfam PF04659 Archaeal flagella protein 300 393 1.7E-29 T 23-10-2018 IPR006752 Archaeal flagella protein FlaD/E domain GO:0097588 A3L04_10560 4a224ed04de5d841185998fd9fc0e4f5 421 PIRSF PIRSF017066 1 421 5.0E-142 T 23-10-2018 IPR016682 Flagella accessory protein D, predicted, archaeal A3L04_10560 4a224ed04de5d841185998fd9fc0e4f5 421 ProDom PD012942 FLAGELLUM FLAGELLA-RELATED E D ACCESSORY FLAGELLA ARCHAEAL FLAD SIMILAR D 304 405 3.0E-48 T 23-10-2018 IPR006752 Archaeal flagella protein FlaD/E domain GO:0097588 A3L04_06475 28c4901825eaf28f9752afe1679d08a6 408 Gene3D G3DSA:2.40.50.140 1 56 1.8E-23 T 23-10-2018 A3L04_06475 28c4901825eaf28f9752afe1679d08a6 408 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 7 400 3.3E-76 T 23-10-2018 A3L04_06475 28c4901825eaf28f9752afe1679d08a6 408 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 340 371 - T 23-10-2018 IPR030390 RNA methyltransferase TrmA, active site A3L04_06475 28c4901825eaf28f9752afe1679d08a6 408 Gene3D G3DSA:3.40.50.150 68 402 1.1E-125 T 23-10-2018 A3L04_06475 28c4901825eaf28f9752afe1679d08a6 408 SUPERFAMILY SSF53335 55 406 3.58E-71 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_06475 28c4901825eaf28f9752afe1679d08a6 408 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 241 401 2.6E-18 T 23-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A3L04_06475 28c4901825eaf28f9752afe1679d08a6 408 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 390 400 - T 23-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site A3L04_06475 28c4901825eaf28f9752afe1679d08a6 408 Gene3D G3DSA:3.40.1350.30 107 251 1.1E-125 T 23-10-2018 A3L04_10675 d73a69d04059e6cc38527c84d9ddeea5 111 Gene3D G3DSA:1.10.10.1220 1 88 4.2E-44 T 23-10-2018 A3L04_04310 61f866e068275a2d8eaa6c037436b208 334 SMART SM01136 4 63 1.3E-26 T 23-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A3L04_04310 61f866e068275a2d8eaa6c037436b208 334 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 67 117 9.0E-16 T 23-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 A3L04_04310 61f866e068275a2d8eaa6c037436b208 334 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 121 180 1.9E-6 T 23-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 A3L04_04310 61f866e068275a2d8eaa6c037436b208 334 Gene3D G3DSA:3.30.2350.10 40 243 1.4E-149 T 23-10-2018 A3L04_04310 61f866e068275a2d8eaa6c037436b208 334 SUPERFAMILY SSF88697 249 332 1.77E-23 T 23-10-2018 IPR015947 PUA-like superfamily A3L04_04310 61f866e068275a2d8eaa6c037436b208 334 TIGRFAM TIGR00425 CBF5: putative rRNA pseudouridine synthase 17 334 1.1E-137 T 23-10-2018 IPR004802 tRNA pseudouridine synthase B family GO:0006396 Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A3L04_04310 61f866e068275a2d8eaa6c037436b208 334 Pfam PF08068 DKCLD (NUC011) domain 15 63 6.3E-19 T 23-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A3L04_04310 61f866e068275a2d8eaa6c037436b208 334 Hamap MF_01081 Probable tRNA pseudouridine synthase B [truB]. 40 325 52.11 T 23-10-2018 IPR026326 Probable tRNA pseudouridine synthase B, archaeal GO:0006396 A3L04_04310 61f866e068275a2d8eaa6c037436b208 334 Pfam PF01472 PUA domain 251 323 1.2E-20 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L04_04310 61f866e068275a2d8eaa6c037436b208 334 Gene3D G3DSA:2.30.130.70 23 332 1.4E-149 T 23-10-2018 A3L04_04310 61f866e068275a2d8eaa6c037436b208 334 SUPERFAMILY SSF55120 21 247 4.56E-77 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L04_04310 61f866e068275a2d8eaa6c037436b208 334 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 247 1.0E-23 T 23-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A3L04_04310 61f866e068275a2d8eaa6c037436b208 334 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 240 320 5.8E-11 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L04_04310 61f866e068275a2d8eaa6c037436b208 334 SMART SM00359 251 325 9.7E-24 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L04_08275 1c1c31871949bd35031b4b6fa3f1da59 482 Gene3D G3DSA:3.60.20.10 2 218 1.5E-43 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L04_08275 1c1c31871949bd35031b4b6fa3f1da59 482 Gene3D G3DSA:3.40.50.620 219 476 1.9E-75 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_08275 1c1c31871949bd35031b4b6fa3f1da59 482 PIRSF PIRSF001589 361 475 1.0E-17 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A3L04_08275 1c1c31871949bd35031b4b6fa3f1da59 482 PIRSF PIRSF001589 1 366 3.4E-62 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A3L04_08275 1c1c31871949bd35031b4b6fa3f1da59 482 Pfam PF00733 Asparagine synthase 364 453 2.4E-19 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A3L04_08275 1c1c31871949bd35031b4b6fa3f1da59 482 Pfam PF00733 Asparagine synthase 225 358 3.1E-36 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A3L04_08275 1c1c31871949bd35031b4b6fa3f1da59 482 Pfam PF13537 Glutamine amidotransferase domain 60 179 1.4E-24 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A3L04_08275 1c1c31871949bd35031b4b6fa3f1da59 482 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 360 1.3E-88 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A3L04_08275 1c1c31871949bd35031b4b6fa3f1da59 482 SUPERFAMILY SSF56235 13 210 1.46E-41 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L04_08275 1c1c31871949bd35031b4b6fa3f1da59 482 SUPERFAMILY SSF52402 219 453 7.72E-60 T 23-10-2018 A3L04_04540 fa8b7d7ad625d41b94789993814a7ce4 260 Gene3D G3DSA:3.40.50.300 4 233 2.3E-66 T 23-10-2018 A3L04_04540 fa8b7d7ad625d41b94789993814a7ce4 260 SUPERFAMILY SSF52540 3 236 9.82E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_04540 fa8b7d7ad625d41b94789993814a7ce4 260 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 212 6.3E-25 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L04_04540 fa8b7d7ad625d41b94789993814a7ce4 260 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 4 251 3.2E-118 T 23-10-2018 IPR010224 ATP binding protein MinD, archaea A3L04_04540 fa8b7d7ad625d41b94789993814a7ce4 260 PIRSF PIRSF003092 1 260 4.6E-64 T 23-10-2018 IPR025501 ATP binding protein MinD A3L04_04540 fa8b7d7ad625d41b94789993814a7ce4 260 SMART SM00382 3 163 0.0034 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_04365 58319ab331138442bbe5def1d254acf8 120 Gene3D G3DSA:3.100.10.10 5 120 8.1E-41 T 23-10-2018 A3L04_04365 58319ab331138442bbe5def1d254acf8 120 Pfam PF17135 Ribosomal protein 60S L18 and 50S L18e 11 119 5.9E-17 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P A3L04_04365 58319ab331138442bbe5def1d254acf8 120 Hamap MF_00329 50S ribosomal protein L18e [rpl18e]. 4 120 30.223 T 23-10-2018 IPR022947 Ribosomal protein L18e, archaea A3L04_04365 58319ab331138442bbe5def1d254acf8 120 ProSitePatterns PS01106 Ribosomal protein L18e signature. 35 52 - T 23-10-2018 IPR021132 Ribosomal protein L18e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_04365 58319ab331138442bbe5def1d254acf8 120 SUPERFAMILY SSF52080 5 120 1.57E-31 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily A3L04_01485 9c0434e4cc47c9527bed586f2a490e2d 461 Pfam PF01637 ATPase domain predominantly from Archaea 2 210 9.5E-29 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_01485 9c0434e4cc47c9527bed586f2a490e2d 461 Gene3D G3DSA:3.40.50.300 1 172 2.3E-35 T 23-10-2018 A3L04_01485 9c0434e4cc47c9527bed586f2a490e2d 461 SUPERFAMILY SSF52540 1 218 1.21E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01485 9c0434e4cc47c9527bed586f2a490e2d 461 Pfam PF03008 Archaea bacterial proteins of unknown function 322 413 2.5E-21 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L04_00725 32524db5f36623c102e5416b41e1547d 183 PIRSF PIRSF000498 1 183 6.3E-54 T 23-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L04_00725 32524db5f36623c102e5416b41e1547d 183 Gene3D G3DSA:2.40.30.20 1 77 5.2E-15 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L04_00725 32524db5f36623c102e5416b41e1547d 183 Pfam PF00677 Lumazine binding domain 19 75 2.0E-10 T 23-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L04_00725 32524db5f36623c102e5416b41e1547d 183 Pfam PF00677 Lumazine binding domain 88 171 1.2E-21 T 23-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L04_00725 32524db5f36623c102e5416b41e1547d 183 SUPERFAMILY SSF63380 81 182 3.32E-29 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L04_00725 32524db5f36623c102e5416b41e1547d 183 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 182 1.6E-49 T 23-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L04_00725 32524db5f36623c102e5416b41e1547d 183 Gene3D G3DSA:2.40.30.20 90 183 1.8E-28 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L04_00725 32524db5f36623c102e5416b41e1547d 183 SUPERFAMILY SSF63380 1 81 2.81E-14 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L04_00895 e21d87ec0cdd5bc3f4b3dae9662f0daa 193 ProDom PD016744 UPF0215 ST0304 TK2033 MA4269 PAE0952 SSO0256 NEQ431 MK0057 PTO0905 TV0037 71 189 3.0E-45 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A3L04_00895 e21d87ec0cdd5bc3f4b3dae9662f0daa 193 Gene3D G3DSA:3.30.2170.10 3 193 3.3E-59 T 23-10-2018 A3L04_00895 e21d87ec0cdd5bc3f4b3dae9662f0daa 193 PIRSF PIRSF006380 1 193 3.3E-72 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A3L04_00895 e21d87ec0cdd5bc3f4b3dae9662f0daa 193 Pfam PF01949 Protein of unknown function DUF99 8 186 1.2E-61 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A3L04_00895 e21d87ec0cdd5bc3f4b3dae9662f0daa 193 Hamap MF_00582 UPF0215 protein . 9 187 33.616 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A3L04_07140 bad6ef5adaf0579f2634c7f5e47a6734 348 Gene3D G3DSA:3.40.190.10 32 307 1.4E-108 T 23-10-2018 A3L04_07140 bad6ef5adaf0579f2634c7f5e47a6734 348 SUPERFAMILY SSF53850 29 337 1.17E-78 T 23-10-2018 A3L04_07140 bad6ef5adaf0579f2634c7f5e47a6734 348 PIRSF PIRSF002825 2 336 4.5E-50 T 23-10-2018 IPR026045 Ferric binding protein A3L04_07140 bad6ef5adaf0579f2634c7f5e47a6734 348 Gene3D G3DSA:3.40.190.10 133 332 1.4E-108 T 23-10-2018 A3L04_07140 bad6ef5adaf0579f2634c7f5e47a6734 348 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 29 331 3.7E-90 T 23-10-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030975 A3L04_07140 bad6ef5adaf0579f2634c7f5e47a6734 348 Pfam PF13416 Bacterial extracellular solute-binding protein 46 304 1.6E-34 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein A3L04_04380 198ab97108d5b8a691263e7ad561ca5b 65 Gene3D G3DSA:1.10.10.60 1 65 4.0E-35 T 23-10-2018 A3L04_04380 198ab97108d5b8a691263e7ad561ca5b 65 Pfam PF01194 RNA polymerases N / 8 kDa subunit 1 59 6.1E-32 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L04_04380 198ab97108d5b8a691263e7ad561ca5b 65 ProSitePatterns PS01112 RNA polymerases N / 8 Kd subunits signature. 2 11 - T 23-10-2018 IPR020789 RNA polymerases, subunit N, zinc binding site GO:0003677|GO:0003899|GO:0006351|GO:0008270 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L04_04380 198ab97108d5b8a691263e7ad561ca5b 65 Hamap MF_00250 DNA-directed RNA polymerase subunit N [rpoN]. 1 63 24.65 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L04_04380 198ab97108d5b8a691263e7ad561ca5b 65 ProDom PD006539 RNA POLYMERASE DNA-DIRECTED SUBUNIT TRANSFERASE NUCLEOTIDYLTRANSFERASE METAL-BINDING ZINC TRANSCRIPTION N 10 49 5.0E-16 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L04_04380 198ab97108d5b8a691263e7ad561ca5b 65 PIRSF PIRSF005653 1 65 1.9E-33 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L04_04380 198ab97108d5b8a691263e7ad561ca5b 65 SUPERFAMILY SSF46924 1 63 2.75E-29 T 23-10-2018 IPR023580 RNA polymerase subunit RPB10 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L04_03695 6cab2e7e4637d0255b30ef8c949b1d2b 87 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 50 2.1E-11 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L04_03695 6cab2e7e4637d0255b30ef8c949b1d2b 87 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 47 1.8E-11 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L04_03695 6cab2e7e4637d0255b30ef8c949b1d2b 87 Gene3D G3DSA:2.10.260.10 3 44 6.3E-9 T 23-10-2018 A3L04_03695 6cab2e7e4637d0255b30ef8c949b1d2b 87 SMART SM00966 6 51 2.2E-11 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L04_03695 6cab2e7e4637d0255b30ef8c949b1d2b 87 SUPERFAMILY SSF89447 4 47 2.35E-10 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L04_07075 d4fda46899d9c2dca36029526a5eba1f 232 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 15 218 1.7E-78 T 23-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A3L04_07075 d4fda46899d9c2dca36029526a5eba1f 232 SUPERFAMILY SSF53271 13 217 6.14E-56 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L04_07075 d4fda46899d9c2dca36029526a5eba1f 232 Hamap MF_01218_A Uracil phosphoribosyltransferase [upp]. 9 217 41.844 T 23-10-2018 IPR034331 Uracil phosphoribosyltransferase, archaea GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A3L04_07075 d4fda46899d9c2dca36029526a5eba1f 232 Pfam PF14681 Uracil phosphoribosyltransferase 15 217 7.8E-51 T 23-10-2018 A3L04_07075 d4fda46899d9c2dca36029526a5eba1f 232 Gene3D G3DSA:3.40.50.2020 1 218 1.0E-60 T 23-10-2018 A3L04_02910 f08967824d9ac1bea57446efc80a2f50 149 SUPERFAMILY SSF88723 7 147 7.57E-29 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_02910 f08967824d9ac1bea57446efc80a2f50 149 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 7 130 9.808 T 23-10-2018 IPR022907 VapC family GO:0004540 A3L04_02910 f08967824d9ac1bea57446efc80a2f50 149 Gene3D G3DSA:3.40.50.1010 1 149 9.8E-45 T 23-10-2018 A3L04_02910 f08967824d9ac1bea57446efc80a2f50 149 PIRSF PIRSF016154 1 149 3.1E-71 T 23-10-2018 IPR016647 Probable ribonuclease VapC, Thermococci A3L04_05795 d9ce74a245dad86e0245fce1bd45bb90 423 PRINTS PR00415 Aconitase family signature 298 309 3.7E-19 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A3L04_05795 d9ce74a245dad86e0245fce1bd45bb90 423 PRINTS PR00415 Aconitase family signature 354 367 3.7E-19 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A3L04_05795 d9ce74a245dad86e0245fce1bd45bb90 423 PRINTS PR00415 Aconitase family signature 114 127 3.7E-19 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A3L04_05795 d9ce74a245dad86e0245fce1bd45bb90 423 PRINTS PR00415 Aconitase family signature 128 143 3.7E-19 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A3L04_05795 d9ce74a245dad86e0245fce1bd45bb90 423 PRINTS PR00415 Aconitase family signature 190 203 3.7E-19 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A3L04_05795 d9ce74a245dad86e0245fce1bd45bb90 423 ProSitePatterns PS01244 Aconitase family signature 2. 354 367 - T 23-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A3L04_05795 d9ce74a245dad86e0245fce1bd45bb90 423 Gene3D G3DSA:3.30.499.20 4 270 1.9E-107 T 23-10-2018 A3L04_05795 d9ce74a245dad86e0245fce1bd45bb90 423 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 4 419 5.9E-190 T 23-10-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 A3L04_05795 d9ce74a245dad86e0245fce1bd45bb90 423 Gene3D G3DSA:3.30.499.10 273 421 2.6E-56 T 23-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 A3L04_05795 d9ce74a245dad86e0245fce1bd45bb90 423 Pfam PF00330 Aconitase family (aconitate hydratase) 7 413 1.9E-104 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A3L04_05795 d9ce74a245dad86e0245fce1bd45bb90 423 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 3 421 52.118 T 23-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A3L04_05795 d9ce74a245dad86e0245fce1bd45bb90 423 ProSitePatterns PS00450 Aconitase family signature 1. 294 310 - T 23-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A3L04_05795 d9ce74a245dad86e0245fce1bd45bb90 423 TIGRFAM TIGR02083 LEU2: 3-isopropylmalate dehydratase, large subunit 3 421 3.6E-239 T 23-10-2018 IPR011823 3-isopropylmalate dehydratase, large subunit, bacteria GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A3L04_05795 d9ce74a245dad86e0245fce1bd45bb90 423 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 3 419 8.4E-168 T 23-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A3L04_05795 d9ce74a245dad86e0245fce1bd45bb90 423 SUPERFAMILY SSF53732 1 421 1.29E-150 T 23-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 A3L04_07905 df9f5f4b1b3412b3dd8dbeadd3f93f32 278 SUPERFAMILY SSF103481 181 275 7.98E-13 T 23-10-2018 A3L04_07905 df9f5f4b1b3412b3dd8dbeadd3f93f32 278 SUPERFAMILY SSF103481 39 136 1.83E-12 T 23-10-2018 A3L04_07905 df9f5f4b1b3412b3dd8dbeadd3f93f32 278 Pfam PF00892 EamA-like transporter family 147 275 4.6E-22 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L04_07905 df9f5f4b1b3412b3dd8dbeadd3f93f32 278 Pfam PF00892 EamA-like transporter family 4 133 2.1E-23 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L04_00595 f37108b9dbe6b2574192e86a28c696b1 451 Pfam PF01637 ATPase domain predominantly from Archaea 6 197 2.6E-19 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_00595 f37108b9dbe6b2574192e86a28c696b1 451 SUPERFAMILY SSF46785 237 314 1.26E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_00595 f37108b9dbe6b2574192e86a28c696b1 451 Pfam PF03008 Archaea bacterial proteins of unknown function 306 405 3.3E-33 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L04_00595 f37108b9dbe6b2574192e86a28c696b1 451 Gene3D G3DSA:3.40.50.300 2 163 4.3E-29 T 23-10-2018 A3L04_00595 f37108b9dbe6b2574192e86a28c696b1 451 SUPERFAMILY SSF52980 338 405 3.33E-6 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L04_00595 f37108b9dbe6b2574192e86a28c696b1 451 PRINTS PR01874 DNA repair protein radA signature 14 42 7.2E-5 T 23-10-2018 A3L04_00595 f37108b9dbe6b2574192e86a28c696b1 451 PRINTS PR01874 DNA repair protein radA signature 251 274 7.2E-5 T 23-10-2018 A3L04_00595 f37108b9dbe6b2574192e86a28c696b1 451 SUPERFAMILY SSF52540 4 236 7.37E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01885 0f41e904925bbebb0dfaaef6a918e8bf 434 SUPERFAMILY SSF55681 114 429 4.15E-90 T 23-10-2018 A3L04_01885 0f41e904925bbebb0dfaaef6a918e8bf 434 Gene3D G3DSA:3.30.930.10 106 434 3.0E-119 T 23-10-2018 A3L04_01885 0f41e904925bbebb0dfaaef6a918e8bf 434 PRINTS PR01042 Aspartyl-tRNA synthetase signature 389 403 1.8E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_01885 0f41e904925bbebb0dfaaef6a918e8bf 434 PRINTS PR01042 Aspartyl-tRNA synthetase signature 349 365 1.8E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_01885 0f41e904925bbebb0dfaaef6a918e8bf 434 PRINTS PR01042 Aspartyl-tRNA synthetase signature 185 197 1.8E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_01885 0f41e904925bbebb0dfaaef6a918e8bf 434 PRINTS PR01042 Aspartyl-tRNA synthetase signature 201 214 1.8E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_01885 0f41e904925bbebb0dfaaef6a918e8bf 434 Pfam PF01336 OB-fold nucleic acid binding domain 19 98 9.1E-12 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L04_01885 0f41e904925bbebb0dfaaef6a918e8bf 434 Pfam PF00152 tRNA synthetases class II (D, K and N) 116 428 1.3E-89 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_01885 0f41e904925bbebb0dfaaef6a918e8bf 434 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 14 433 6.3E-128 T 23-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 A3L04_01885 0f41e904925bbebb0dfaaef6a918e8bf 434 Gene3D G3DSA:2.40.50.140 1 104 1.1E-28 T 23-10-2018 A3L04_01885 0f41e904925bbebb0dfaaef6a918e8bf 434 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 4 434 37.796 T 23-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 A3L04_01885 0f41e904925bbebb0dfaaef6a918e8bf 434 SUPERFAMILY SSF50249 3 100 5.78E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_04450 af093582e9e8a30ed94821883af68d71 418 SUPERFAMILY SSF48179 198 289 5.95E-28 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A3L04_04450 af093582e9e8a30ed94821883af68d71 418 SUPERFAMILY SSF51735 1 192 2.91E-49 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_04450 af093582e9e8a30ed94821883af68d71 418 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 199 285 5.1E-26 T 23-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L04_04450 af093582e9e8a30ed94821883af68d71 418 Gene3D G3DSA:3.40.50.720 1 196 2.1E-74 T 23-10-2018 A3L04_04450 af093582e9e8a30ed94821883af68d71 418 PIRSF PIRSF500136 1 414 2.9E-142 T 23-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A3L04_04450 af093582e9e8a30ed94821883af68d71 418 SMART SM00984 312 403 1.6E-32 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L04_04450 af093582e9e8a30ed94821883af68d71 418 SUPERFAMILY SSF52413 301 401 8.63E-24 T 23-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 A3L04_04450 af093582e9e8a30ed94821883af68d71 418 PIRSF PIRSF000124 1 409 1.4E-82 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L04_04450 af093582e9e8a30ed94821883af68d71 418 Gene3D G3DSA:3.40.50.720 230 418 2.2E-68 T 23-10-2018 A3L04_04450 af093582e9e8a30ed94821883af68d71 418 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 399 4.2E-128 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L04_04450 af093582e9e8a30ed94821883af68d71 418 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 313 401 6.7E-23 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L04_04450 af093582e9e8a30ed94821883af68d71 418 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 178 1.0E-51 T 23-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L04_00620 f590807e4fdedc8299b69bc468121274 272 PIRSF PIRSF000097 1 270 5.8E-42 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L04_00620 f590807e4fdedc8299b69bc468121274 272 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 131 148 - T 23-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A3L04_00620 f590807e4fdedc8299b69bc468121274 272 Pfam PF00248 Aldo/keto reductase family 15 266 7.2E-62 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain A3L04_00620 f590807e4fdedc8299b69bc468121274 272 PRINTS PR00069 Aldo-keto reductase signature 131 148 2.1E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L04_00620 f590807e4fdedc8299b69bc468121274 272 PRINTS PR00069 Aldo-keto reductase signature 206 230 2.1E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L04_00620 f590807e4fdedc8299b69bc468121274 272 PRINTS PR00069 Aldo-keto reductase signature 99 117 2.1E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L04_00620 f590807e4fdedc8299b69bc468121274 272 PRINTS PR00069 Aldo-keto reductase signature 43 67 2.1E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L04_00620 f590807e4fdedc8299b69bc468121274 272 Gene3D G3DSA:3.20.20.100 7 269 7.6E-90 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A3L04_00620 f590807e4fdedc8299b69bc468121274 272 SUPERFAMILY SSF51430 10 266 2.23E-79 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A3L04_03940 aa375e27dd98bc5fe3a3e3154c6d7fad 438 Pfam PF04715 Anthranilate synthase component I, N terminal region 9 131 2.7E-18 T 23-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A3L04_03940 aa375e27dd98bc5fe3a3e3154c6d7fad 438 SUPERFAMILY SSF56322 8 430 1.37E-124 T 23-10-2018 IPR005801 ADC synthase GO:0009058 A3L04_03940 aa375e27dd98bc5fe3a3e3154c6d7fad 438 PRINTS PR00095 Anthranilate synthase component I signature 270 283 5.4E-18 T 23-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A3L04_03940 aa375e27dd98bc5fe3a3e3154c6d7fad 438 PRINTS PR00095 Anthranilate synthase component I signature 364 378 5.4E-18 T 23-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A3L04_03940 aa375e27dd98bc5fe3a3e3154c6d7fad 438 PRINTS PR00095 Anthranilate synthase component I signature 284 297 5.4E-18 T 23-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A3L04_03940 aa375e27dd98bc5fe3a3e3154c6d7fad 438 PRINTS PR00095 Anthranilate synthase component I signature 379 393 5.4E-18 T 23-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A3L04_03940 aa375e27dd98bc5fe3a3e3154c6d7fad 438 Pfam PF00425 chorismate binding enzyme 170 421 6.8E-93 T 23-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal A3L04_03940 aa375e27dd98bc5fe3a3e3154c6d7fad 438 TIGRFAM TIGR01820 TrpE-arch: anthranilate synthase component I 11 430 2.1E-169 T 23-10-2018 IPR010116 Anthranilate synthase component I, archaeal type GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A3L04_03940 aa375e27dd98bc5fe3a3e3154c6d7fad 438 Gene3D G3DSA:3.60.120.10 3 434 1.7E-135 T 23-10-2018 IPR005801 ADC synthase GO:0009058 A3L04_03685 3c4a3f0dc67a5c8c3c5e25216cd47013 207 Gene3D G3DSA:1.10.287.1080 119 207 1.5E-28 T 23-10-2018 A3L04_03685 3c4a3f0dc67a5c8c3c5e25216cd47013 207 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 122 202 4.5E-29 T 23-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A3L04_03685 3c4a3f0dc67a5c8c3c5e25216cd47013 207 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 122 205 5.4E-15 T 23-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 A3L04_03685 3c4a3f0dc67a5c8c3c5e25216cd47013 207 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 5 107 28.794 T 23-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A3L04_03685 3c4a3f0dc67a5c8c3c5e25216cd47013 207 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 31 103 4.3E-31 T 23-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A3L04_03685 3c4a3f0dc67a5c8c3c5e25216cd47013 207 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 53 106 7.0E-24 T 23-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A3L04_03685 3c4a3f0dc67a5c8c3c5e25216cd47013 207 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 119 202 19.305 T 23-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A3L04_03685 3c4a3f0dc67a5c8c3c5e25216cd47013 207 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 6 207 36.75 T 23-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 A3L04_03685 3c4a3f0dc67a5c8c3c5e25216cd47013 207 SUPERFAMILY SSF101386 121 206 4.67E-23 T 23-10-2018 A3L04_03685 3c4a3f0dc67a5c8c3c5e25216cd47013 207 SUPERFAMILY SSF141734 3 111 1.7E-43 T 23-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 A3L04_03685 3c4a3f0dc67a5c8c3c5e25216cd47013 207 Gene3D G3DSA:3.10.20.400 2 94 1.3E-34 T 23-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 A3L04_03835 a7ef5d866d42f9fdfd642c3d0533909c 263 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 3 256 7.7E-131 T 23-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A3L04_03835 a7ef5d866d42f9fdfd642c3d0533909c 263 Gene3D G3DSA:3.20.20.70 2 263 3.0E-112 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_03835 a7ef5d866d42f9fdfd642c3d0533909c 263 Pfam PF00793 DAHP synthetase I family 19 255 2.9E-80 T 23-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A3L04_03835 a7ef5d866d42f9fdfd642c3d0533909c 263 SUPERFAMILY SSF51569 8 256 4.85E-98 T 23-10-2018 A3L04_04965 447714738424684bd665df55d19840fd 348 SUPERFAMILY SSF53187 5 345 1.5E-72 T 23-10-2018 A3L04_04965 447714738424684bd665df55d19840fd 348 PIRSF PIRSF001123 1 348 1.5E-125 T 23-10-2018 IPR008007 Peptidase M42 A3L04_04965 447714738424684bd665df55d19840fd 348 Pfam PF05343 M42 glutamyl aminopeptidase 45 335 1.2E-113 T 23-10-2018 IPR008007 Peptidase M42 A3L04_04965 447714738424684bd665df55d19840fd 348 SUPERFAMILY SSF101821 68 177 1.45E-30 T 23-10-2018 A3L04_04965 447714738424684bd665df55d19840fd 348 Gene3D G3DSA:2.40.30.40 68 161 7.2E-141 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A3L04_04965 447714738424684bd665df55d19840fd 348 Gene3D G3DSA:3.40.630.10 6 336 7.2E-141 T 23-10-2018 A3L04_04520 f9a78c33b82402053db724a7190c6744 958 Pfam PF14890 Intein splicing domain 108 574 5.2E-15 T 23-10-2018 A3L04_04520 f9a78c33b82402053db724a7190c6744 958 Gene3D G3DSA:2.170.16.10 103 214 1.3E-10 T 23-10-2018 A3L04_04520 f9a78c33b82402053db724a7190c6744 958 SUPERFAMILY SSF51294 97 574 2.55E-28 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L04_04520 f9a78c33b82402053db724a7190c6744 958 SMART SM00306 96 197 2.3E-21 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L04_04520 f9a78c33b82402053db724a7190c6744 958 SUPERFAMILY SSF103365 574 958 4.18E-147 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A3L04_04520 f9a78c33b82402053db724a7190c6744 958 SMART SM00305 532 580 1.4E-11 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L04_04520 f9a78c33b82402053db724a7190c6744 958 PRINTS PR00379 Intein signature 355 367 2.2E-13 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_04520 f9a78c33b82402053db724a7190c6744 958 PRINTS PR00379 Intein signature 395 410 2.2E-13 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_04520 f9a78c33b82402053db724a7190c6744 958 PRINTS PR00379 Intein signature 164 177 2.2E-13 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_04520 f9a78c33b82402053db724a7190c6744 958 PRINTS PR00379 Intein signature 569 578 2.2E-13 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_04520 f9a78c33b82402053db724a7190c6744 958 PRINTS PR00379 Intein signature 245 257 2.2E-13 T 23-10-2018 IPR006142 Intein GO:0016539 A3L04_04520 f9a78c33b82402053db724a7190c6744 958 Gene3D G3DSA:3.90.1860.10 556 958 8.0E-182 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A3L04_04520 f9a78c33b82402053db724a7190c6744 958 Gene3D G3DSA:3.90.1860.10 1 102 2.6E-40 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A3L04_04520 f9a78c33b82402053db724a7190c6744 958 SUPERFAMILY SSF55608 342 449 1.36E-13 T 23-10-2018 IPR027434 Homing endonuclease A3L04_04520 f9a78c33b82402053db724a7190c6744 958 Pfam PF14528 LAGLIDADG-like domain 354 440 4.8E-15 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L04_04520 f9a78c33b82402053db724a7190c6744 958 Pfam PF01139 tRNA-splicing ligase RtcB 46 958 3.3E-178 T 23-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A3L04_04520 f9a78c33b82402053db724a7190c6744 958 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 98 177 8.3E-13 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L04_04520 f9a78c33b82402053db724a7190c6744 958 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 553 575 1.8E-7 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L04_04520 f9a78c33b82402053db724a7190c6744 958 SUPERFAMILY SSF103365 4 98 5.1E-30 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A3L04_04520 f9a78c33b82402053db724a7190c6744 958 Gene3D G3DSA:3.10.28.10 244 435 2.2E-20 T 23-10-2018 IPR027434 Homing endonuclease A3L04_02070 ecd1389f547003c705fb2706cbd1bebb 414 Gene3D G3DSA:3.20.20.140 41 407 3.3E-111 T 23-10-2018 A3L04_02070 ecd1389f547003c705fb2706cbd1bebb 414 ProSitePatterns PS00482 Dihydroorotase signature 1. 55 63 - T 23-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_02070 ecd1389f547003c705fb2706cbd1bebb 414 SUPERFAMILY SSF51338 313 399 3.17E-24 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L04_02070 ecd1389f547003c705fb2706cbd1bebb 414 ProSitePatterns PS00483 Dihydroorotase signature 2. 270 281 - T 23-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_02070 ecd1389f547003c705fb2706cbd1bebb 414 SUPERFAMILY SSF51556 52 330 3.33E-75 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L04_02070 ecd1389f547003c705fb2706cbd1bebb 414 SUPERFAMILY SSF51338 15 61 8.64E-9 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L04_02070 ecd1389f547003c705fb2706cbd1bebb 414 Pfam PF01979 Amidohydrolase family 48 212 4.2E-16 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A3L04_02070 ecd1389f547003c705fb2706cbd1bebb 414 Pfam PF01979 Amidohydrolase family 262 383 1.9E-10 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A3L04_02070 ecd1389f547003c705fb2706cbd1bebb 414 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 16 386 5.6E-133 T 23-10-2018 A3L04_02070 ecd1389f547003c705fb2706cbd1bebb 414 Hamap MF_00220_A Dihydroorotase [pyrC]. 3 391 66.011 T 23-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_08405 38759b8b2e026cc3ba7d100f3d3cb5ce 394 Gene3D G3DSA:3.40.50.1100 98 194 6.5E-135 T 23-10-2018 A3L04_08405 38759b8b2e026cc3ba7d100f3d3cb5ce 394 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 62 363 2.8E-84 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L04_08405 38759b8b2e026cc3ba7d100f3d3cb5ce 394 TIGRFAM TIGR00260 thrC: threonine synthase 49 370 2.3E-109 T 23-10-2018 IPR004450 Threonine synthase-like A3L04_08405 38759b8b2e026cc3ba7d100f3d3cb5ce 394 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 90 103 - T 23-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A3L04_08405 38759b8b2e026cc3ba7d100f3d3cb5ce 394 PIRSF PIRSF038945 28 394 2.3E-151 T 23-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 A3L04_08405 38759b8b2e026cc3ba7d100f3d3cb5ce 394 Gene3D G3DSA:3.40.50.1100 54 369 6.5E-135 T 23-10-2018 A3L04_08405 38759b8b2e026cc3ba7d100f3d3cb5ce 394 SUPERFAMILY SSF53686 2 386 4.19E-120 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L04_07395 b9758187cfbab134a0a4aaee493528e3 51 Gene3D G3DSA:2.20.28.70 1 48 3.6E-18 T 23-10-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L04_07395 b9758187cfbab134a0a4aaee493528e3 51 Hamap MF_00788 50S ribosomal protein L40e [rpl40e]. 2 47 19.187 T 23-10-2018 IPR023657 Ribosomal protein L40e, archaeal GO:0003735|GO:0005840|GO:0006412 A3L04_07395 b9758187cfbab134a0a4aaee493528e3 51 SMART SM01377 1 46 3.9E-8 T 23-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L04_07395 b9758187cfbab134a0a4aaee493528e3 51 SUPERFAMILY SSF57829 2 46 2.75E-15 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L04_08965 ee90f0cd5e7d6e1d3da483249b3968c7 428 Gene3D G3DSA:1.10.645.10 6 424 1.9E-108 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_08965 ee90f0cd5e7d6e1d3da483249b3968c7 428 SUPERFAMILY SSF56762 8 424 8.24E-97 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_08965 ee90f0cd5e7d6e1d3da483249b3968c7 428 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 415 424 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 A3L04_08965 ee90f0cd5e7d6e1d3da483249b3968c7 428 Pfam PF00374 Nickel-dependent hydrogenase 43 129 6.7E-12 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L04_08965 ee90f0cd5e7d6e1d3da483249b3968c7 428 Pfam PF00374 Nickel-dependent hydrogenase 253 424 4.5E-12 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L04_00315 b9d86f1fae3cedeeefc48567c5bc156b 429 Gene3D G3DSA:1.20.1250.20 1 218 1.3E-15 T 23-10-2018 A3L04_00315 b9d86f1fae3cedeeefc48567c5bc156b 429 Pfam PF13347 MFS/sugar transport protein 40 394 4.4E-15 T 23-10-2018 A3L04_00315 b9d86f1fae3cedeeefc48567c5bc156b 429 SUPERFAMILY SSF103473 3 424 1.31E-41 T 23-10-2018 IPR036259 MFS transporter superfamily A3L04_00315 b9d86f1fae3cedeeefc48567c5bc156b 429 Gene3D G3DSA:1.20.1250.20 227 427 1.0E-18 T 23-10-2018 A3L04_09755 0a356606d93f41e680e36c307cba7956 284 Pfam PF00892 EamA-like transporter family 149 283 6.2E-21 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L04_09755 0a356606d93f41e680e36c307cba7956 284 Pfam PF00892 EamA-like transporter family 3 137 1.0E-24 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L04_09755 0a356606d93f41e680e36c307cba7956 284 SUPERFAMILY SSF103481 197 283 1.96E-11 T 23-10-2018 A3L04_09755 0a356606d93f41e680e36c307cba7956 284 SUPERFAMILY SSF103481 44 138 8.11E-13 T 23-10-2018 A3L04_01205 4dbed91724fea0ab478585cfa25febae 89 Gene3D G3DSA:2.60.40.1240 1 86 1.6E-7 T 23-10-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain superfamily A3L04_02260 faa5fcd46b06c87207f458647f9d7ae4 192 Gene3D G3DSA:1.10.20.10 91 192 7.4E-48 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L04_02260 faa5fcd46b06c87207f458647f9d7ae4 192 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 7.9E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_02260 faa5fcd46b06c87207f458647f9d7ae4 192 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 33 44 7.9E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_02260 faa5fcd46b06c87207f458647f9d7ae4 192 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 14 29 7.9E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_02260 faa5fcd46b06c87207f458647f9d7ae4 192 SUPERFAMILY SSF46785 6 165 1.13E-34 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_02260 faa5fcd46b06c87207f458647f9d7ae4 192 SMART SM00418 12 106 1.8E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_02260 faa5fcd46b06c87207f458647f9d7ae4 192 Pfam PF01022 Bacterial regulatory protein, arsR family 20 64 1.8E-15 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_02260 faa5fcd46b06c87207f458647f9d7ae4 192 Gene3D G3DSA:1.10.10.10 1 90 3.8E-32 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_09700 cbf0b9d8e29f43489cb38100d9984861 292 Pfam PF00953 Glycosyl transferase family 4 65 206 1.2E-31 T 23-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 A3L04_02380 306f1dd5ae30d5d89d47e989213339fa 178 SUPERFAMILY SSF50324 1 176 3.27E-67 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L04_02380 306f1dd5ae30d5d89d47e989213339fa 178 Gene3D G3DSA:3.90.80.10 1 178 7.0E-74 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L04_02380 306f1dd5ae30d5d89d47e989213339fa 178 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 15 171 36.191 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L04_02380 306f1dd5ae30d5d89d47e989213339fa 178 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L04_02380 306f1dd5ae30d5d89d47e989213339fa 178 Pfam PF00719 Inorganic pyrophosphatase 20 171 3.0E-56 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L04_06780 5ae666d95c5386241cf59aa88588ed4f 156 Gene3D G3DSA:2.20.28.10 118 155 4.1E-21 T 23-10-2018 A3L04_06780 5ae666d95c5386241cf59aa88588ed4f 156 Gene3D G3DSA:3.40.50.1010 1 117 6.0E-46 T 23-10-2018 A3L04_06780 5ae666d95c5386241cf59aa88588ed4f 156 Pfam PF17146 PIN domain of ribonuclease 3 86 7.9E-21 T 23-10-2018 IPR033411 Ribonuclease, PIN domain Reactome: R-HSA-6791226 A3L04_06780 5ae666d95c5386241cf59aa88588ed4f 156 SMART SM00670 1 99 2.8E-10 T 23-10-2018 IPR002716 PIN domain A3L04_06780 5ae666d95c5386241cf59aa88588ed4f 156 SUPERFAMILY SSF88723 3 111 4.97E-7 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_02410 dc0d7656653af7f43f05946973619890 170 Pfam PF01047 MarR family 40 81 1.4E-5 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A3L04_02410 dc0d7656653af7f43f05946973619890 170 Gene3D G3DSA:1.10.10.10 2 86 1.3E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_02410 dc0d7656653af7f43f05946973619890 170 SUPERFAMILY SSF46785 3 130 2.45E-21 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_02410 dc0d7656653af7f43f05946973619890 170 PIRSF PIRSF006707 1 169 1.6E-39 T 23-10-2018 IPR026282 DNA-binding protein, MJ1563 type A3L04_04815 dd8abbda43892d884dcd62e8b7df27d0 99 ProSitePatterns PS00709 Ribosomal protein L30e signature 1. 13 37 - T 23-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_04815 dd8abbda43892d884dcd62e8b7df27d0 99 Gene3D G3DSA:3.30.1330.30 1 99 2.7E-39 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L04_04815 dd8abbda43892d884dcd62e8b7df27d0 99 ProSitePatterns PS00993 Ribosomal protein L30e signature 2. 69 89 - T 23-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_04815 dd8abbda43892d884dcd62e8b7df27d0 99 Hamap MF_00481 50S ribosomal protein L30e [rpl30e]. 1 98 30.778 T 23-10-2018 IPR000231 Ribosomal protein L30e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_04815 dd8abbda43892d884dcd62e8b7df27d0 99 SUPERFAMILY SSF55315 1 96 1.85E-28 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L04_04815 dd8abbda43892d884dcd62e8b7df27d0 99 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 5 94 2.8E-22 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 A3L04_02035 aeb44479f04964b9c2cfa42a6e1aa03d 214 Pfam PF01813 ATP synthase subunit D 13 206 6.8E-63 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L04_02035 aeb44479f04964b9c2cfa42a6e1aa03d 214 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 6 209 6.6E-71 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L04_02035 aeb44479f04964b9c2cfa42a6e1aa03d 214 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 4 211 26.027 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L04_04415 df19515909046b364e20942d2aae5916 333 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 108 119 - T 23-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 A3L04_04415 df19515909046b364e20942d2aae5916 333 SUPERFAMILY SSF55060 182 328 1.6E-38 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A3L04_04415 df19515909046b364e20942d2aae5916 333 SUPERFAMILY SSF54211 3 179 3.34E-47 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L04_04415 df19515909046b364e20942d2aae5916 333 Gene3D G3DSA:3.30.230.10 2 181 6.0E-52 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L04_04415 df19515909046b364e20942d2aae5916 333 Pfam PF00288 GHMP kinases N terminal domain 102 168 6.9E-17 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A3L04_04415 df19515909046b364e20942d2aae5916 333 Pfam PF08544 GHMP kinases C terminal 242 309 3.1E-13 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain A3L04_04415 df19515909046b364e20942d2aae5916 333 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 7 297 1.2E-85 T 23-10-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A3L04_04415 df19515909046b364e20942d2aae5916 333 Hamap MF_00217 Mevalonate kinase [mvk]. 3 326 60.047 T 23-10-2018 IPR022937 Mevalonate kinase, archaeal GO:0004496 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922 A3L04_04415 df19515909046b364e20942d2aae5916 333 Gene3D G3DSA:3.30.70.890 186 318 2.8E-41 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A3L04_04415 df19515909046b364e20942d2aae5916 333 PRINTS PR00959 Mevalonate kinase family signature 7 31 6.7E-29 T 23-10-2018 A3L04_04415 df19515909046b364e20942d2aae5916 333 PRINTS PR00959 Mevalonate kinase family signature 106 128 6.7E-29 T 23-10-2018 A3L04_04415 df19515909046b364e20942d2aae5916 333 PRINTS PR00959 Mevalonate kinase family signature 282 299 6.7E-29 T 23-10-2018 A3L04_04415 df19515909046b364e20942d2aae5916 333 PRINTS PR00959 Mevalonate kinase family signature 149 168 6.7E-29 T 23-10-2018 A3L04_06600 87129fb14e7fd92427b449dde015acb9 348 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 280 292 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site A3L04_06600 87129fb14e7fd92427b449dde015acb9 348 Gene3D G3DSA:3.40.350.10 1 122 1.3E-33 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L04_06600 87129fb14e7fd92427b449dde015acb9 348 SUPERFAMILY SSF53092 8 124 2.96E-27 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L04_06600 87129fb14e7fd92427b449dde015acb9 348 PRINTS PR00599 Methionine aminopeptidase-1 signature 302 314 2.8E-5 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L04_06600 87129fb14e7fd92427b449dde015acb9 348 PRINTS PR00599 Methionine aminopeptidase-1 signature 204 220 2.8E-5 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L04_06600 87129fb14e7fd92427b449dde015acb9 348 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 124 6.4E-18 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 A3L04_06600 87129fb14e7fd92427b449dde015acb9 348 SUPERFAMILY SSF55920 123 347 5.76E-85 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like A3L04_06600 87129fb14e7fd92427b449dde015acb9 348 Gene3D G3DSA:3.90.230.10 123 348 2.5E-92 T 23-10-2018 A3L04_06600 87129fb14e7fd92427b449dde015acb9 348 Pfam PF00557 Metallopeptidase family M24 132 334 1.9E-73 T 23-10-2018 IPR000994 Peptidase M24 A3L04_02670 099059110b2dc39f089e22e811090b9a 398 Pfam PF00534 Glycosyl transferases group 1 209 371 4.1E-19 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L04_02670 099059110b2dc39f089e22e811090b9a 398 SUPERFAMILY SSF53756 6 391 2.27E-56 T 23-10-2018 A3L04_02670 099059110b2dc39f089e22e811090b9a 398 Gene3D G3DSA:3.40.50.2000 2 205 6.8E-20 T 23-10-2018 A3L04_02670 099059110b2dc39f089e22e811090b9a 398 Gene3D G3DSA:3.40.50.2000 206 393 1.3E-31 T 23-10-2018 A3L04_02670 099059110b2dc39f089e22e811090b9a 398 Pfam PF13439 Glycosyltransferase Family 4 18 197 2.4E-18 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L04_05115 eccb73a5078b6ef22bf8d6d75f6836a7 272 Gene3D G3DSA:3.40.91.80 1 272 2.2E-156 T 23-10-2018 IPR038365 EcoRII, C-terminal domain superfamily A3L04_05115 eccb73a5078b6ef22bf8d6d75f6836a7 272 SUPERFAMILY SSF52980 3 258 2.57E-49 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L04_05115 eccb73a5078b6ef22bf8d6d75f6836a7 272 Pfam PF09019 EcoRII C terminal 84 181 3.2E-12 T 23-10-2018 IPR015109 Restriction endonuclease, type II, EcoRII, C-terminal GO:0003677|GO:0009036|GO:0009307 A3L04_06080 69f4640d5be5c60fa2229139c220cb15 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 2.6E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A3L04_06080 69f4640d5be5c60fa2229139c220cb15 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 2.6E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A3L04_06080 69f4640d5be5c60fa2229139c220cb15 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 2.6E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A3L04_06080 69f4640d5be5c60fa2229139c220cb15 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 2.6E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A3L04_06080 69f4640d5be5c60fa2229139c220cb15 476 Pfam PF09190 DALR domain 356 415 1.8E-17 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A3L04_06080 69f4640d5be5c60fa2229139c220cb15 476 SMART SM00840 356 417 8.3E-14 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A3L04_06080 69f4640d5be5c60fa2229139c220cb15 476 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 474 39.673 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A3L04_06080 69f4640d5be5c60fa2229139c220cb15 476 SUPERFAMILY SSF52374 4 314 3.33E-113 T 23-10-2018 A3L04_06080 69f4640d5be5c60fa2229139c220cb15 476 Gene3D G3DSA:1.20.120.640 306 473 8.9E-36 T 23-10-2018 A3L04_06080 69f4640d5be5c60fa2229139c220cb15 476 SUPERFAMILY SSF47323 316 473 4.8E-33 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_06080 69f4640d5be5c60fa2229139c220cb15 476 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 314 1.4E-139 T 23-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 A3L04_06080 69f4640d5be5c60fa2229139c220cb15 476 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 473 3.2E-181 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A3L04_06080 69f4640d5be5c60fa2229139c220cb15 476 Gene3D G3DSA:3.40.50.620 1 305 2.4E-152 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_07920 d8a49d791aabbcf0afe131a07c2ab64d 123 Hamap MF_00326 50S ribosomal protein L7Ae [rpl7ae]. 3 122 35.674 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_07920 d8a49d791aabbcf0afe131a07c2ab64d 123 SUPERFAMILY SSF55315 4 120 5.3E-40 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L04_07920 d8a49d791aabbcf0afe131a07c2ab64d 123 PRINTS PR00884 Ribosomal protein HS6 signature 6 17 6.6E-32 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_07920 d8a49d791aabbcf0afe131a07c2ab64d 123 PRINTS PR00884 Ribosomal protein HS6 signature 77 87 6.6E-32 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_07920 d8a49d791aabbcf0afe131a07c2ab64d 123 PRINTS PR00884 Ribosomal protein HS6 signature 40 50 6.6E-32 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_07920 d8a49d791aabbcf0afe131a07c2ab64d 123 PRINTS PR00884 Ribosomal protein HS6 signature 50 61 6.6E-32 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_07920 d8a49d791aabbcf0afe131a07c2ab64d 123 PRINTS PR00884 Ribosomal protein HS6 signature 91 107 6.6E-32 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_07920 d8a49d791aabbcf0afe131a07c2ab64d 123 TIGRFAM TIGR03677 eL8_ribo: ribosomal protein eL8 6 121 3.2E-57 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_07920 d8a49d791aabbcf0afe131a07c2ab64d 123 ProSitePatterns PS01082 Ribosomal protein L7Ae signature. 70 87 - T 23-10-2018 IPR004037 Ribosomal protein L7Ae conserved site GO:0042254|GO:1990904 Reactome: R-HSA-6791226 A3L04_07920 d8a49d791aabbcf0afe131a07c2ab64d 123 Gene3D G3DSA:3.30.1330.30 1 123 2.7E-43 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L04_07920 d8a49d791aabbcf0afe131a07c2ab64d 123 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 18 110 5.2E-32 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 A3L04_07920 d8a49d791aabbcf0afe131a07c2ab64d 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 32 46 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A3L04_07920 d8a49d791aabbcf0afe131a07c2ab64d 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 67 77 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A3L04_07920 d8a49d791aabbcf0afe131a07c2ab64d 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 77 91 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A3L04_07920 d8a49d791aabbcf0afe131a07c2ab64d 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 51 64 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A3L04_09665 58c377c14158a40ab4b6f4e9c5922ca0 234 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_09665 58c377c14158a40ab4b6f4e9c5922ca0 234 SUPERFAMILY SSF52540 3 216 7.46E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09665 58c377c14158a40ab4b6f4e9c5922ca0 234 SMART SM00382 27 206 9.8E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_09665 58c377c14158a40ab4b6f4e9c5922ca0 234 Gene3D G3DSA:3.40.50.300 1 229 3.3E-55 T 23-10-2018 A3L04_09665 58c377c14158a40ab4b6f4e9c5922ca0 234 Pfam PF00005 ABC transporter 23 159 2.4E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_01985 c7dd038d664f74e30bf26d220e6e1091 508 SUPERFAMILY SSF82866 312 492 7.06E-23 T 23-10-2018 A3L04_01985 c7dd038d664f74e30bf26d220e6e1091 508 Gene3D G3DSA:1.20.1640.10 309 494 4.7E-12 T 23-10-2018 A3L04_01985 c7dd038d664f74e30bf26d220e6e1091 508 Pfam PF02355 Protein export membrane protein 327 491 1.7E-17 T 23-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A3L04_01985 c7dd038d664f74e30bf26d220e6e1091 508 Gene3D G3DSA:3.30.70.3400 34 115 8.3E-11 T 23-10-2018 A3L04_01985 c7dd038d664f74e30bf26d220e6e1091 508 Hamap MF_01463_A Protein translocase subunit SecD [secD]. 5 506 19.504 T 23-10-2018 IPR024912 Protein translocase subunit SecD, archaeal A3L04_01985 c7dd038d664f74e30bf26d220e6e1091 508 Pfam PF07549 SecD/SecF GG Motif 25 52 9.4E-8 T 23-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site A3L04_02030 367579e443aa218902dc1135731f07f9 462 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 8 74 7.4E-13 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L04_02030 367579e443aa218902dc1135731f07f9 462 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 131 349 2.1E-68 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L04_02030 367579e443aa218902dc1135731f07f9 462 Gene3D G3DSA:3.40.50.12240 1 458 4.7E-196 T 23-10-2018 A3L04_02030 367579e443aa218902dc1135731f07f9 462 SUPERFAMILY SSF52540 78 354 2.42E-88 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_02030 367579e443aa218902dc1135731f07f9 462 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 2 458 63.364 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L04_02030 367579e443aa218902dc1135731f07f9 462 TIGRFAM TIGR01041 ATP_syn_B_arch: ATP synthase archaeal, B subunit 4 460 7.6E-272 T 23-10-2018 IPR005724 ATPase, A1 complex, beta subunit GO:0015986|GO:0033178|GO:0046933 A3L04_02030 367579e443aa218902dc1135731f07f9 462 SUPERFAMILY SSF47917 362 419 3.92E-10 T 23-10-2018 A3L04_02030 367579e443aa218902dc1135731f07f9 462 PIRSF PIRSF039114 1 462 4.5E-260 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L04_02030 367579e443aa218902dc1135731f07f9 462 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 340 349 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L04_05395 a17b17994afe8b17b4055e2411295058 191 PRINTS PR00686 Transcription initiation factor TFIID signature 11 26 1.3E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L04_05395 a17b17994afe8b17b4055e2411295058 191 PRINTS PR00686 Transcription initiation factor TFIID signature 35 54 1.3E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L04_05395 a17b17994afe8b17b4055e2411295058 191 PRINTS PR00686 Transcription initiation factor TFIID signature 125 140 1.3E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L04_05395 a17b17994afe8b17b4055e2411295058 191 PRINTS PR00686 Transcription initiation factor TFIID signature 54 72 1.3E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L04_05395 a17b17994afe8b17b4055e2411295058 191 PRINTS PR00686 Transcription initiation factor TFIID signature 102 118 1.3E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L04_05395 a17b17994afe8b17b4055e2411295058 191 PRINTS PR00686 Transcription initiation factor TFIID signature 144 160 1.3E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L04_05395 a17b17994afe8b17b4055e2411295058 191 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 100 181 3.1E-28 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L04_05395 a17b17994afe8b17b4055e2411295058 191 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 9 88 2.6E-26 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L04_05395 a17b17994afe8b17b4055e2411295058 191 SUPERFAMILY SSF55945 96 182 8.01E-30 T 23-10-2018 A3L04_05395 a17b17994afe8b17b4055e2411295058 191 Gene3D G3DSA:3.30.310.10 93 182 1.8E-35 T 23-10-2018 IPR012295 TBP domain superfamily A3L04_05395 a17b17994afe8b17b4055e2411295058 191 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 129 178 - T 23-10-2018 IPR030491 TATA-box binding protein, conserved site A3L04_05395 a17b17994afe8b17b4055e2411295058 191 Hamap MF_00408 TATA-box-binding protein [tbp]. 5 184 37.698 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L04_05395 a17b17994afe8b17b4055e2411295058 191 SUPERFAMILY SSF55945 5 96 6.75E-28 T 23-10-2018 A3L04_05395 a17b17994afe8b17b4055e2411295058 191 Gene3D G3DSA:3.30.310.10 1 92 2.4E-29 T 23-10-2018 IPR012295 TBP domain superfamily A3L04_04845 c82e4feb7d46df6894142c8a8cfbd107 410 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 3 398 1.7E-134 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L04_04845 c82e4feb7d46df6894142c8a8cfbd107 410 Gene3D G3DSA:3.30.70.3160 35 114 1.5E-108 T 23-10-2018 A3L04_04845 c82e4feb7d46df6894142c8a8cfbd107 410 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 71 84 - T 23-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 A3L04_04845 c82e4feb7d46df6894142c8a8cfbd107 410 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 5 401 9.0E-83 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L04_04845 c82e4feb7d46df6894142c8a8cfbd107 410 Gene3D G3DSA:1.10.1510.30 158 243 1.5E-108 T 23-10-2018 A3L04_04845 c82e4feb7d46df6894142c8a8cfbd107 410 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 1 403 29.719 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L04_04845 c82e4feb7d46df6894142c8a8cfbd107 410 PIRSF PIRSF037016 375 405 0.0075 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L04_04845 c82e4feb7d46df6894142c8a8cfbd107 410 PIRSF PIRSF037016 23 378 3.2E-53 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L04_04845 c82e4feb7d46df6894142c8a8cfbd107 410 SUPERFAMILY SSF55120 3 400 1.73E-90 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L04_04845 c82e4feb7d46df6894142c8a8cfbd107 410 Gene3D G3DSA:3.30.2350.20 115 397 1.5E-108 T 23-10-2018 A3L04_02020 df8a4c52e94711787366688ec59eef67 103 Pfam PF01990 ATP synthase (F/14-kDa) subunit 3 83 1.3E-19 T 23-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L04_02020 df8a4c52e94711787366688ec59eef67 103 SUPERFAMILY SSF159468 3 102 1.57E-20 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L04_02020 df8a4c52e94711787366688ec59eef67 103 Hamap MF_00312 V-type ATP synthase subunit F [atpF]. 1 102 21.436 T 23-10-2018 IPR022944 ATPase, V1 complex, subunit F, bacterial/archaeal A3L04_02020 df8a4c52e94711787366688ec59eef67 103 Gene3D G3DSA:3.40.50.10580 1 103 9.4E-37 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L04_00910 b6a5192cc4702378314fdb2005b996a4 174 PIRSF PIRSF015617 1 174 2.8E-63 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 A3L04_00910 b6a5192cc4702378314fdb2005b996a4 174 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 7 174 3.4E-63 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 A3L04_00910 b6a5192cc4702378314fdb2005b996a4 174 Gene3D G3DSA:3.40.50.300 1 174 3.9E-67 T 23-10-2018 A3L04_00910 b6a5192cc4702378314fdb2005b996a4 174 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 2 174 2.3E-74 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 A3L04_00910 b6a5192cc4702378314fdb2005b996a4 174 SUPERFAMILY SSF52540 3 174 9.39E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09470 1caf91dcac294d46f8611013deefa4c6 211 Gene3D G3DSA:3.20.20.70 1 207 6.8E-68 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_09470 1caf91dcac294d46f8611013deefa4c6 211 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 3 201 8.4E-56 T 23-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L04_09470 1caf91dcac294d46f8611013deefa4c6 211 SUPERFAMILY SSF51366 2 207 2.07E-58 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L04_09470 1caf91dcac294d46f8611013deefa4c6 211 Hamap MF_01200_A Orotidine 5'-phosphate decarboxylase [pyrF]. 2 211 39.363 T 23-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L04_09470 1caf91dcac294d46f8611013deefa4c6 211 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 54 67 - T 23-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L04_09470 1caf91dcac294d46f8611013deefa4c6 211 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 2 201 4.8E-40 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L04_09470 1caf91dcac294d46f8611013deefa4c6 211 SMART SM00934 1 201 2.4E-63 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L04_03640 137b3f33a006d5a92ddba4c740626eee 294 Pfam PF13393 Histidyl-tRNA synthetase 9 196 1.4E-10 T 23-10-2018 A3L04_03640 137b3f33a006d5a92ddba4c740626eee 294 SUPERFAMILY SSF55681 12 253 5.5E-31 T 23-10-2018 A3L04_03640 137b3f33a006d5a92ddba4c740626eee 294 Gene3D G3DSA:3.30.930.10 15 255 5.8E-33 T 23-10-2018 A3L04_09820 5407686e3c6d9950c8bc5e0bd764ae4b 264 Pfam PF11495 Archaeal transcriptional regulator TrmB 125 262 5.8E-7 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal A3L04_09820 5407686e3c6d9950c8bc5e0bd764ae4b 264 Gene3D G3DSA:3.30.870.10 122 264 3.7E-82 T 23-10-2018 A3L04_09820 5407686e3c6d9950c8bc5e0bd764ae4b 264 SUPERFAMILY SSF46785 10 96 6.67E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_09820 5407686e3c6d9950c8bc5e0bd764ae4b 264 Gene3D G3DSA:1.10.10.10 1 75 1.2E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_09820 5407686e3c6d9950c8bc5e0bd764ae4b 264 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 77 4.8E-20 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L04_09820 5407686e3c6d9950c8bc5e0bd764ae4b 264 SUPERFAMILY SSF56024 142 261 5.23E-5 T 23-10-2018 A3L04_04560 46802c34eafb298c4baabf22ba307a99 75 Pfam PF02597 ThiS family 4 75 1.4E-8 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L04_04560 46802c34eafb298c4baabf22ba307a99 75 SUPERFAMILY SSF54285 3 75 1.87E-9 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L04_04560 46802c34eafb298c4baabf22ba307a99 75 Gene3D G3DSA:3.10.20.30 4 75 3.8E-13 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L04_08130 d782fb8bea98244f4d3d0d5a06563f3e 142 Gene3D G3DSA:2.60.120.630 1 142 7.6E-55 T 23-10-2018 IPR023131 Mth639-like domain superfamily A3L04_08130 d782fb8bea98244f4d3d0d5a06563f3e 142 Pfam PF04027 Domain of unknown function (DUF371) 6 137 2.6E-52 T 23-10-2018 IPR007171 Protein of unknown function DUF371 A3L04_06135 48437a9dc93e47b8159cde5da76c92ca 449 TIGRFAM TIGR00797 matE: MATE efflux family protein 26 420 1.6E-76 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L04_06135 48437a9dc93e47b8159cde5da76c92ca 449 Pfam PF01554 MatE 247 407 8.0E-28 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L04_06135 48437a9dc93e47b8159cde5da76c92ca 449 Pfam PF01554 MatE 26 186 3.8E-29 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L04_06135 48437a9dc93e47b8159cde5da76c92ca 449 PIRSF PIRSF006603 2 449 1.7E-140 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L04_06560 236080865a62942363ace1dc016bfb5c 416 Gene3D G3DSA:1.10.4160.10 3 403 2.9E-54 T 23-10-2018 IPR038271 Purine-cytosine permease superfamily A3L04_06560 236080865a62942363ace1dc016bfb5c 416 PIRSF PIRSF002744 2 416 4.9E-58 T 23-10-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 A3L04_06560 236080865a62942363ace1dc016bfb5c 416 TIGRFAM TIGR02358 thia_cytX: putative hydroxymethylpyrimidine transporter CytX 15 411 1.4E-148 T 23-10-2018 IPR012732 Hydroxymethylpyrimidine transporter CytX A3L04_06560 236080865a62942363ace1dc016bfb5c 416 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 15 379 6.7E-35 T 23-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 A3L04_10085 b06df12acc711c0901923cf69237bfe6 376 Gene3D G3DSA:1.20.1090.10 186 375 3.4E-54 T 23-10-2018 A3L04_10085 b06df12acc711c0901923cf69237bfe6 376 Gene3D G3DSA:3.40.50.1970 1 184 5.8E-45 T 23-10-2018 A3L04_10085 b06df12acc711c0901923cf69237bfe6 376 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 365 1.5E-99 T 23-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A3L04_10085 b06df12acc711c0901923cf69237bfe6 376 SUPERFAMILY SSF56796 2 375 2.22E-99 T 23-10-2018 A3L04_00575 a64fa785223af86f56fbb6aecea8507a 277 Pfam PF01040 UbiA prenyltransferase family 22 259 2.4E-42 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A3L04_00575 a64fa785223af86f56fbb6aecea8507a 277 Gene3D G3DSA:1.10.357.140 9 157 2.7E-17 T 23-10-2018 A3L04_00575 a64fa785223af86f56fbb6aecea8507a 277 Hamap MF_01286 Digeranylgeranylglyceryl phosphate synthase. 3 273 22.081 T 23-10-2018 IPR023547 Digeranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005886|GO:0008654|GO:0047295 KEGG: 00564+2.5.1.42|MetaCyc: PWY-6349 A3L04_00575 a64fa785223af86f56fbb6aecea8507a 277 Gene3D G3DSA:1.20.120.1780 158 276 4.5E-6 T 23-10-2018 A3L04_06635 197cdfeef569fda2ce952d2b89f51227 97 Gene3D G3DSA:2.30.30.70 2 97 1.3E-37 T 23-10-2018 IPR036948 Ribosomal protein L21 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_06635 197cdfeef569fda2ce952d2b89f51227 97 Hamap MF_00369 50S ribosomal protein L21e [rpl21e]. 3 97 31.04 T 23-10-2018 IPR022856 Ribosomal protein L21e, archaeal A3L04_06635 197cdfeef569fda2ce952d2b89f51227 97 Pfam PF01157 Ribosomal protein L21e 6 96 8.5E-33 T 23-10-2018 IPR001147 Ribosomal protein L21e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_06635 197cdfeef569fda2ce952d2b89f51227 97 SUPERFAMILY SSF50104 5 97 1.08E-32 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L04_06635 197cdfeef569fda2ce952d2b89f51227 97 ProSitePatterns PS01171 Ribosomal protein L21e signature. 38 63 - T 23-10-2018 IPR018259 Ribosomal protein L21e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_00730 fc6c602034802cc6540c34bbb6c095ff 355 PIRSF PIRSF006769 1 351 2.6E-109 T 23-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 A3L04_00730 fc6c602034802cc6540c34bbb6c095ff 355 Gene3D G3DSA:3.40.140.10 1 143 9.8E-52 T 23-10-2018 A3L04_00730 fc6c602034802cc6540c34bbb6c095ff 355 Pfam PF01872 RibD C-terminal domain 150 344 1.5E-31 T 23-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A3L04_00730 fc6c602034802cc6540c34bbb6c095ff 355 SUPERFAMILY SSF53927 3 147 4.35E-49 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A3L04_00730 fc6c602034802cc6540c34bbb6c095ff 355 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 7 345 2.2E-100 T 23-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 A3L04_00730 fc6c602034802cc6540c34bbb6c095ff 355 Gene3D G3DSA:3.40.430.10 144 348 1.7E-46 T 23-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A3L04_00730 fc6c602034802cc6540c34bbb6c095ff 355 SUPERFAMILY SSF53597 150 346 5.44E-42 T 23-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A3L04_00730 fc6c602034802cc6540c34bbb6c095ff 355 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 50 91 - T 23-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A3L04_00730 fc6c602034802cc6540c34bbb6c095ff 355 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 2 102 1.1E-23 T 23-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A3L04_08825 4512fe6825394682e79249208c03a0bf 265 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 4 245 7.4E-95 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A3L04_08825 4512fe6825394682e79249208c03a0bf 265 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 47 87 - T 23-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 A3L04_08825 4512fe6825394682e79249208c03a0bf 265 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 265 43.263 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A3L04_08825 4512fe6825394682e79249208c03a0bf 265 Gene3D G3DSA:3.40.50.1580 1 264 2.3E-101 T 23-10-2018 A3L04_08825 4512fe6825394682e79249208c03a0bf 265 Pfam PF01048 Phosphorylase superfamily 3 245 4.1E-55 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A3L04_08825 4512fe6825394682e79249208c03a0bf 265 SUPERFAMILY SSF53167 1 263 3.27E-93 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A3L04_03130 fea15c99c4c7f7aedf1666ef734eebc6 302 Pfam PF00288 GHMP kinases N terminal domain 93 151 1.5E-6 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A3L04_03130 fea15c99c4c7f7aedf1666ef734eebc6 302 SUPERFAMILY SSF54211 1 158 3.64E-15 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L04_03130 fea15c99c4c7f7aedf1666ef734eebc6 302 PIRSF PIRSF016896 1 296 4.7E-99 T 23-10-2018 IPR012043 Pantoate kinase KEGG: 00770+2.7.1.169|MetaCyc: PWY-6654 A3L04_03160 3d742f9a578d85b07fab52a3439f38b1 205 Pfam PF04919 Protein of unknown function (DUF655) 22 197 1.4E-73 T 23-10-2018 IPR007003 Protein of unknown function DUF655 A3L04_03160 3d742f9a578d85b07fab52a3439f38b1 205 Gene3D G3DSA:1.10.150.280 92 189 1.6E-43 T 23-10-2018 A3L04_03160 3d742f9a578d85b07fab52a3439f38b1 205 SUPERFAMILY SSF160975 22 198 1.83E-94 T 23-10-2018 A3L04_03160 3d742f9a578d85b07fab52a3439f38b1 205 Gene3D G3DSA:2.40.50.140 22 91 6.8E-24 T 23-10-2018 A3L04_01650 0751b86e9ba0f8162baf4ac82694efdf 352 SUPERFAMILY SSF52540 24 161 7.65E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01650 0751b86e9ba0f8162baf4ac82694efdf 352 Gene3D G3DSA:3.40.50.300 9 214 3.7E-28 T 23-10-2018 A3L04_01650 0751b86e9ba0f8162baf4ac82694efdf 352 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 36 210 2.1E-40 T 23-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain A3L04_06830 c7295929ed479bf56f7a13c0da2b95e0 188 SUPERFAMILY SSF52540 7 175 1.32E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_06830 c7295929ed479bf56f7a13c0da2b95e0 188 Pfam PF13189 Cytidylate kinase-like family 7 160 8.1E-27 T 23-10-2018 A3L04_06830 c7295929ed479bf56f7a13c0da2b95e0 188 Hamap MF_00239 Cytidylate kinase [cmk]. 6 178 49.779 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A3L04_06830 c7295929ed479bf56f7a13c0da2b95e0 188 TIGRFAM TIGR02173 cyt_kin_arch: putative cytidylate kinase 6 175 1.7E-65 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A3L04_06830 c7295929ed479bf56f7a13c0da2b95e0 188 Gene3D G3DSA:3.40.50.300 2 177 2.2E-46 T 23-10-2018 A3L04_04625 92784cd8e3f90c04f31d142559ae051f 443 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 10 427 4.4E-227 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L04_04625 92784cd8e3f90c04f31d142559ae051f 443 Gene3D G3DSA:3.40.50.1100 11 236 2.2E-178 T 23-10-2018 A3L04_04625 92784cd8e3f90c04f31d142559ae051f 443 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 18 424 42.974 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L04_04625 92784cd8e3f90c04f31d142559ae051f 443 Gene3D G3DSA:3.40.50.1100 10 417 2.2E-178 T 23-10-2018 A3L04_04625 92784cd8e3f90c04f31d142559ae051f 443 PIRSF PIRSF001413 6 430 6.4E-161 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L04_04625 92784cd8e3f90c04f31d142559ae051f 443 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 103 117 - T 23-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L04_04625 92784cd8e3f90c04f31d142559ae051f 443 PIRSF PIRSF500824 1 433 2.2E-217 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L04_04625 92784cd8e3f90c04f31d142559ae051f 443 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 75 410 1.3E-45 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L04_04625 92784cd8e3f90c04f31d142559ae051f 443 SUPERFAMILY SSF53686 24 422 4.06E-111 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L04_05275 4f30c791eb86dd5e6802089a1e8eeb58 387 Pfam PF04981 NMD3 family 4 273 7.2E-62 T 23-10-2018 IPR007064 Nmd3, N-terminal A3L04_05275 4f30c791eb86dd5e6802089a1e8eeb58 387 Gene3D G3DSA:2.40.50.140 329 385 2.7E-7 T 23-10-2018 A3L04_05275 4f30c791eb86dd5e6802089a1e8eeb58 387 SUPERFAMILY SSF50249 329 380 7.28E-6 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_06950 09771ebf8cf84807c5d7f4b6f56a6631 144 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 107 7.1E-22 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A3L04_06950 09771ebf8cf84807c5d7f4b6f56a6631 144 SUPERFAMILY SSF53146 1 115 9.81E-30 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L04_06950 09771ebf8cf84807c5d7f4b6f56a6631 144 Gene3D G3DSA:3.30.420.130 1 120 1.9E-29 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L04_08165 ff6868cda91ecfbfefa57b1b9ea95093 267 SUPERFAMILY SSF159659 2 253 4.18E-44 T 23-10-2018 A3L04_08165 ff6868cda91ecfbfefa57b1b9ea95093 267 Gene3D G3DSA:3.40.50.10900 1 244 2.9E-74 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily A3L04_08165 ff6868cda91ecfbfefa57b1b9ea95093 267 Pfam PF09754 PAC2 family 19 241 2.1E-46 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 A3L04_08165 ff6868cda91ecfbfefa57b1b9ea95093 267 TIGRFAM TIGR00162 TIGR00162: TIGR00162 family protein 9 263 1.8E-77 T 23-10-2018 IPR004426 Conserved hypothetical protein CHP00062 A3L04_09030 ff1b5677643003c17fca471328410bb0 724 SMART SM00490 467 547 3.0E-8 T 23-10-2018 IPR001650 Helicase, C-terminal A3L04_09030 ff1b5677643003c17fca471328410bb0 724 Gene3D G3DSA:3.40.50.300 425 589 9.8E-16 T 23-10-2018 A3L04_09030 ff1b5677643003c17fca471328410bb0 724 Pfam PF00270 DEAD/DEAH box helicase 232 409 3.6E-13 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L04_09030 ff1b5677643003c17fca471328410bb0 724 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 14 206 1.0E-21 T 23-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain A3L04_09030 ff1b5677643003c17fca471328410bb0 724 Pfam PF00271 Helicase conserved C-terminal domain 448 547 4.7E-8 T 23-10-2018 IPR001650 Helicase, C-terminal A3L04_09030 ff1b5677643003c17fca471328410bb0 724 SMART SM00487 226 438 9.7E-16 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L04_09030 ff1b5677643003c17fca471328410bb0 724 Gene3D G3DSA:1.10.3210.30 1 166 4.5E-13 T 23-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily A3L04_09030 ff1b5677643003c17fca471328410bb0 724 SUPERFAMILY SSF52540 239 558 1.66E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09030 ff1b5677643003c17fca471328410bb0 724 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 244 583 1.3E-98 T 23-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core A3L04_09030 ff1b5677643003c17fca471328410bb0 724 Gene3D G3DSA:3.40.50.300 214 416 4.8E-17 T 23-10-2018 A3L04_00125 55e7d1378ef10d7c515b2ee085d70d24 393 SUPERFAMILY SSF48452 36 231 5.39E-12 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L04_00125 55e7d1378ef10d7c515b2ee085d70d24 393 Gene3D G3DSA:1.25.40.10 16 208 6.3E-9 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L04_00125 55e7d1378ef10d7c515b2ee085d70d24 393 SUPERFAMILY SSF48452 215 379 1.06E-10 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L04_00125 55e7d1378ef10d7c515b2ee085d70d24 393 SMART SM00028 30 63 340.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L04_00125 55e7d1378ef10d7c515b2ee085d70d24 393 SMART SM00028 289 322 14.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L04_00125 55e7d1378ef10d7c515b2ee085d70d24 393 SMART SM00028 174 207 270.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L04_00125 55e7d1378ef10d7c515b2ee085d70d24 393 SMART SM00028 127 160 72.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L04_00125 55e7d1378ef10d7c515b2ee085d70d24 393 Gene3D G3DSA:1.25.40.10 212 390 3.8E-6 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L04_00125 55e7d1378ef10d7c515b2ee085d70d24 393 Pfam PF14938 Soluble NSF attachment protein, SNAP 24 202 1.5E-6 T 23-10-2018 A3L04_10695 59dbe99bff5f6d6b450e3ab2869edb54 114 Pfam PF11419 Protein of unknown function (DUF3194) 9 92 4.4E-29 T 23-10-2018 IPR024502 Protein of unknown function DUF3194 A3L04_10695 59dbe99bff5f6d6b450e3ab2869edb54 114 Gene3D G3DSA:3.30.300.100 1 104 1.4E-39 T 23-10-2018 IPR035954 MTH677-like superfamily A3L04_10695 59dbe99bff5f6d6b450e3ab2869edb54 114 SUPERFAMILY SSF110783 8 93 4.84E-7 T 23-10-2018 IPR035954 MTH677-like superfamily A3L04_02900 07a1e0a64ee0c36ef14e05297d03b22d 380 Gene3D G3DSA:3.30.470.30 96 197 6.9E-71 T 23-10-2018 A3L04_02900 07a1e0a64ee0c36ef14e05297d03b22d 380 Pfam PF09414 RNA ligase 86 240 7.1E-19 T 23-10-2018 IPR021122 RNA ligase domain, REL/Rln2 A3L04_02900 07a1e0a64ee0c36ef14e05297d03b22d 380 Gene3D G3DSA:2.20.25.320 7 67 1.6E-32 T 23-10-2018 A3L04_02900 07a1e0a64ee0c36ef14e05297d03b22d 380 PRINTS PR01048 Hypothetical protein Y414 family signature 108 123 1.5E-59 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L04_02900 07a1e0a64ee0c36ef14e05297d03b22d 380 PRINTS PR01048 Hypothetical protein Y414 family signature 219 232 1.5E-59 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L04_02900 07a1e0a64ee0c36ef14e05297d03b22d 380 PRINTS PR01048 Hypothetical protein Y414 family signature 42 56 1.5E-59 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L04_02900 07a1e0a64ee0c36ef14e05297d03b22d 380 PRINTS PR01048 Hypothetical protein Y414 family signature 87 100 1.5E-59 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L04_02900 07a1e0a64ee0c36ef14e05297d03b22d 380 PRINTS PR01048 Hypothetical protein Y414 family signature 291 305 1.5E-59 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L04_02900 07a1e0a64ee0c36ef14e05297d03b22d 380 PRINTS PR01048 Hypothetical protein Y414 family signature 138 153 1.5E-59 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L04_02900 07a1e0a64ee0c36ef14e05297d03b22d 380 PRINTS PR01048 Hypothetical protein Y414 family signature 64 82 1.5E-59 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L04_02900 07a1e0a64ee0c36ef14e05297d03b22d 380 PRINTS PR01048 Hypothetical protein Y414 family signature 355 375 1.5E-59 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L04_02900 07a1e0a64ee0c36ef14e05297d03b22d 380 PRINTS PR01048 Hypothetical protein Y414 family signature 260 278 1.5E-59 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L04_02900 07a1e0a64ee0c36ef14e05297d03b22d 380 PRINTS PR01048 Hypothetical protein Y414 family signature 164 185 1.5E-59 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L04_02900 07a1e0a64ee0c36ef14e05297d03b22d 380 Gene3D G3DSA:3.30.70.3360 314 362 3.3E-41 T 23-10-2018 A3L04_02900 07a1e0a64ee0c36ef14e05297d03b22d 380 Gene3D G3DSA:3.30.1490.70 70 241 6.9E-71 T 23-10-2018 A3L04_02900 07a1e0a64ee0c36ef14e05297d03b22d 380 SUPERFAMILY SSF56091 62 237 4.52E-38 T 23-10-2018 A3L04_02900 07a1e0a64ee0c36ef14e05297d03b22d 380 Gene3D G3DSA:3.30.70.3350 244 375 3.3E-41 T 23-10-2018 A3L04_02900 07a1e0a64ee0c36ef14e05297d03b22d 380 TIGRFAM TIGR01209 TIGR01209: RNA ligase, Pab1020 family 10 380 9.4E-159 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L04_03480 0b6fd59e2f55152252c4d1bc60f0e015 236 Gene3D G3DSA:3.30.160.770 13 123 1.1E-36 T 23-10-2018 A3L04_03480 0b6fd59e2f55152252c4d1bc60f0e015 236 Pfam PF03719 Ribosomal protein S5, C-terminal domain 146 211 1.0E-21 T 23-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 A3L04_03480 0b6fd59e2f55152252c4d1bc60f0e015 236 Hamap MF_01307_A 30S ribosomal protein S5 [rpsE]. 9 213 48.243 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03480 0b6fd59e2f55152252c4d1bc60f0e015 236 SUPERFAMILY SSF54211 139 211 2.3E-19 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L04_03480 0b6fd59e2f55152252c4d1bc60f0e015 236 SUPERFAMILY SSF54768 63 126 3.35E-18 T 23-10-2018 A3L04_03480 0b6fd59e2f55152252c4d1bc60f0e015 236 TIGRFAM TIGR01020 uS5_euk_arch: ribosomal protein uS5 10 222 1.6E-107 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03480 0b6fd59e2f55152252c4d1bc60f0e015 236 Pfam PF00333 Ribosomal protein S5, N-terminal domain 63 124 7.7E-21 T 23-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 A3L04_03480 0b6fd59e2f55152252c4d1bc60f0e015 236 ProSitePatterns PS00585 Ribosomal protein S5 signature. 78 110 - T 23-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site A3L04_03480 0b6fd59e2f55152252c4d1bc60f0e015 236 Gene3D G3DSA:3.30.230.10 124 219 3.1E-31 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L04_08740 99faa482535ad8dd5bca95ebec75fd9f 375 Pfam PF00579 tRNA synthetases class I (W and Y) 33 351 5.7E-42 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_08740 99faa482535ad8dd5bca95ebec75fd9f 375 Hamap MF_02009 Tyrosine--tRNA ligase [tyrS]. 5 359 48.663 T 23-10-2018 IPR023678 Tyrosine-tRNA ligase, type 4 GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A3L04_08740 99faa482535ad8dd5bca95ebec75fd9f 375 Gene3D G3DSA:3.40.50.620 1 226 2.9E-57 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_08740 99faa482535ad8dd5bca95ebec75fd9f 375 PIRSF PIRSF006588 1 375 1.1E-129 T 23-10-2018 IPR023617 Tyrosine-tRNA ligase, archaeal/eukaryotic-type GO:0004831 KEGG: 00970+6.1.1.1 A3L04_08740 99faa482535ad8dd5bca95ebec75fd9f 375 Gene3D G3DSA:1.10.240.10 227 375 3.3E-57 T 23-10-2018 A3L04_08740 99faa482535ad8dd5bca95ebec75fd9f 375 SUPERFAMILY SSF52374 2 363 1.31E-63 T 23-10-2018 A3L04_07770 9a658975b317a7ffcebc7a6d7df5bf15 632 SUPERFAMILY SSF88688 417 533 2.98E-33 T 23-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily A3L04_07770 9a658975b317a7ffcebc7a6d7df5bf15 632 Pfam PF09210 Domain of unknown function (DUF1957) 429 528 3.2E-26 T 23-10-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 A3L04_07770 9a658975b317a7ffcebc7a6d7df5bf15 632 Gene3D G3DSA:3.20.110.10 1 417 9.4E-173 T 23-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily A3L04_07770 9a658975b317a7ffcebc7a6d7df5bf15 632 Gene3D G3DSA:1.20.1430.10 418 563 1.0E-49 T 23-10-2018 IPR037090 Glycoside hydrolase families 57, central domain KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 A3L04_07770 9a658975b317a7ffcebc7a6d7df5bf15 632 Gene3D G3DSA:1.10.150.20 570 632 4.9E-12 T 23-10-2018 A3L04_07770 9a658975b317a7ffcebc7a6d7df5bf15 632 Pfam PF14520 Helix-hairpin-helix domain 575 624 9.2E-8 T 23-10-2018 A3L04_07770 9a658975b317a7ffcebc7a6d7df5bf15 632 SUPERFAMILY SSF47794 577 629 5.69E-7 T 23-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 A3L04_07770 9a658975b317a7ffcebc7a6d7df5bf15 632 Pfam PF03065 Glycosyl hydrolase family 57 6 392 1.6E-90 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A3L04_07770 9a658975b317a7ffcebc7a6d7df5bf15 632 SUPERFAMILY SSF88713 2 417 2.43E-129 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L04_08365 1b42c68f72d73e92e163fe0fd49888bf 299 PIRSF PIRSF016202 1 292 6.7E-95 T 23-10-2018 IPR007184 Mannoside phosphorylase A3L04_08365 1b42c68f72d73e92e163fe0fd49888bf 299 Pfam PF04041 beta-1,4-mannooligosaccharide phosphorylase 20 283 5.5E-75 T 23-10-2018 IPR007184 Mannoside phosphorylase A3L04_08365 1b42c68f72d73e92e163fe0fd49888bf 299 SUPERFAMILY SSF75005 15 291 9.74E-68 T 23-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A3L04_08365 1b42c68f72d73e92e163fe0fd49888bf 299 Gene3D G3DSA:2.115.10.20 1 284 2.8E-96 T 23-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A3L04_01585 69429721b18debe6d3c421caa3e682a8 257 Pfam PF02540 NAD synthase 7 245 1.1E-84 T 23-10-2018 IPR022310 NAD/GMP synthase A3L04_01585 69429721b18debe6d3c421caa3e682a8 257 SUPERFAMILY SSF52402 4 245 9.92E-75 T 23-10-2018 A3L04_01585 69429721b18debe6d3c421caa3e682a8 257 TIGRFAM TIGR00552 nadE: NAD+ synthetase 13 250 2.1E-80 T 23-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 A3L04_01585 69429721b18debe6d3c421caa3e682a8 257 Gene3D G3DSA:3.40.50.620 1 257 1.0E-92 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_01585 69429721b18debe6d3c421caa3e682a8 257 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 5 248 51.18 T 23-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 A3L04_02210 1ce7282700f119a2fa937f1272451d79 65 Pfam PF01667 Ribosomal protein S27 11 64 6.4E-27 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_02210 1ce7282700f119a2fa937f1272451d79 65 SUPERFAMILY SSF57829 11 65 2.2E-19 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L04_02210 1ce7282700f119a2fa937f1272451d79 65 Gene3D G3DSA:2.20.25.100 11 65 3.5E-25 T 23-10-2018 IPR023407 Ribosomal protein S27e, zinc-binding domain superfamily A3L04_02210 1ce7282700f119a2fa937f1272451d79 65 Hamap MF_00371 30S ribosomal protein S27e [rps27e]. 5 64 22.314 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_02210 1ce7282700f119a2fa937f1272451d79 65 ProSitePatterns PS01168 Ribosomal protein S27e signature. 19 51 - T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_08415 71bade24f7cfb51faa909cd22e3d95b7 356 Gene3D G3DSA:3.40.1160.10 7 269 2.7E-67 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L04_08415 71bade24f7cfb51faa909cd22e3d95b7 356 Gene3D G3DSA:1.20.120.1320 43 123 2.7E-67 T 23-10-2018 A3L04_08415 71bade24f7cfb51faa909cd22e3d95b7 356 SUPERFAMILY SSF53633 6 277 2.36E-60 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L04_08415 71bade24f7cfb51faa909cd22e3d95b7 356 ProSitePatterns PS00324 Aspartokinase signature. 7 15 - T 23-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A3L04_08415 71bade24f7cfb51faa909cd22e3d95b7 356 Pfam PF00696 Amino acid kinase family 6 263 1.2E-50 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A3L04_08415 71bade24f7cfb51faa909cd22e3d95b7 356 TIGRFAM TIGR02078 AspKin_pair: putative Pyrococcus aspartate kinase subunit 6 339 1.9E-131 T 23-10-2018 IPR011819 Pyrococcus aspartate kinase subunit, putative A3L04_08415 71bade24f7cfb51faa909cd22e3d95b7 356 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 6 300 3.2E-63 T 23-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A3L04_02545 aa9c49fb615e3ced7dbd91740a11c39e 285 SUPERFAMILY SSF55608 157 273 2.76E-16 T 23-10-2018 IPR027434 Homing endonuclease A3L04_02545 aa9c49fb615e3ced7dbd91740a11c39e 285 Gene3D G3DSA:3.10.28.10 71 236 9.2E-17 T 23-10-2018 IPR027434 Homing endonuclease A3L04_02545 aa9c49fb615e3ced7dbd91740a11c39e 285 Pfam PF14528 LAGLIDADG-like domain 77 147 8.1E-6 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L04_02545 aa9c49fb615e3ced7dbd91740a11c39e 285 Pfam PF14528 LAGLIDADG-like domain 164 256 4.3E-15 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L04_02545 aa9c49fb615e3ced7dbd91740a11c39e 285 SUPERFAMILY SSF55608 70 148 8.72E-14 T 23-10-2018 IPR027434 Homing endonuclease A3L04_05355 637426e3b59958cd20af9a7b8c989d12 143 SUPERFAMILY SSF88697 1 142 2.4E-41 T 23-10-2018 IPR015947 PUA-like superfamily A3L04_05355 637426e3b59958cd20af9a7b8c989d12 143 Hamap MF_00771 UPF0310 protein . 1 142 27.429 T 23-10-2018 IPR022996 Uncharacterised protein family UPF0310 A3L04_05355 637426e3b59958cd20af9a7b8c989d12 143 Gene3D G3DSA:3.10.590.10 1 142 1.5E-59 T 23-10-2018 A3L04_05355 637426e3b59958cd20af9a7b8c989d12 143 Pfam PF01878 EVE domain 3 141 6.0E-25 T 23-10-2018 IPR002740 EVE domain A3L04_10275 93d1f1f7685e21aafa482e3e1d1c68f9 233 Gene3D G3DSA:3.40.50.1000 96 231 1.3E-40 T 23-10-2018 IPR023214 HAD superfamily A3L04_10275 93d1f1f7685e21aafa482e3e1d1c68f9 233 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 1 224 3.6E-70 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 A3L04_10275 93d1f1f7685e21aafa482e3e1d1c68f9 233 SUPERFAMILY SSF56784 1 229 1.29E-51 T 23-10-2018 IPR036412 HAD-like superfamily A3L04_10275 93d1f1f7685e21aafa482e3e1d1c68f9 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 4.8E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_10275 93d1f1f7685e21aafa482e3e1d1c68f9 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 112 125 4.8E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_10275 93d1f1f7685e21aafa482e3e1d1c68f9 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 161 181 4.8E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_10275 93d1f1f7685e21aafa482e3e1d1c68f9 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 159 4.8E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_10275 93d1f1f7685e21aafa482e3e1d1c68f9 233 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 99 193 1.6E-10 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_10275 93d1f1f7685e21aafa482e3e1d1c68f9 233 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 96 200 9.0E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_10275 93d1f1f7685e21aafa482e3e1d1c68f9 233 Gene3D G3DSA:1.10.150.240 16 95 2.2E-29 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A3L04_10275 93d1f1f7685e21aafa482e3e1d1c68f9 233 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 199 1.1E-29 T 23-10-2018 A3L04_03085 23fe365f075f5eb29295a636cca86ce9 303 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 1 295 27.483 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A3L04_03085 23fe365f075f5eb29295a636cca86ce9 303 Gene3D G3DSA:3.90.650.10 136 295 9.4E-47 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L04_03085 23fe365f075f5eb29295a636cca86ce9 303 Pfam PF00586 AIR synthase related protein, N-terminal domain 21 130 1.7E-16 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L04_03085 23fe365f075f5eb29295a636cca86ce9 303 SUPERFAMILY SSF55326 4 130 2.54E-30 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L04_03085 23fe365f075f5eb29295a636cca86ce9 303 PIRSF PIRSF005303 1 295 1.8E-87 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A3L04_03085 23fe365f075f5eb29295a636cca86ce9 303 Gene3D G3DSA:3.30.1330.10 1 135 2.4E-33 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L04_03085 23fe365f075f5eb29295a636cca86ce9 303 SUPERFAMILY SSF56042 134 284 1.79E-38 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L04_03085 23fe365f075f5eb29295a636cca86ce9 303 Pfam PF02769 AIR synthase related protein, C-terminal domain 141 281 3.6E-7 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L04_03085 23fe365f075f5eb29295a636cca86ce9 303 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 4 295 5.0E-89 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A3L04_04620 728c64c4937db1a944ee58dde14fa3c8 417 Pfam PF03463 eRF1 domain 1 20 136 6.8E-11 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A3L04_04620 728c64c4937db1a944ee58dde14fa3c8 417 SUPERFAMILY SSF55315 275 417 2.24E-39 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L04_04620 728c64c4937db1a944ee58dde14fa3c8 417 Hamap MF_00424 Peptide chain release factor subunit 1 [prf1]. 21 417 44.774 T 23-10-2018 IPR020918 Peptide chain release factor aRF1 GO:0003747|GO:0005737|GO:0006415 A3L04_04620 728c64c4937db1a944ee58dde14fa3c8 417 SMART SM01194 4 138 5.8E-36 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A3L04_04620 728c64c4937db1a944ee58dde14fa3c8 417 Pfam PF03465 eRF1 domain 3 278 417 2.5E-35 T 23-10-2018 IPR005142 eRF1 domain 3 A3L04_04620 728c64c4937db1a944ee58dde14fa3c8 417 Pfam PF03464 eRF1 domain 2 143 275 1.7E-49 T 23-10-2018 IPR005141 eRF1 domain 2 A3L04_04620 728c64c4937db1a944ee58dde14fa3c8 417 Gene3D G3DSA:3.30.1330.30 277 417 2.9E-43 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L04_04620 728c64c4937db1a944ee58dde14fa3c8 417 TIGRFAM TIGR03676 aRF1/eRF1: peptide chain release factor 1, archaeal and eukaryotic forms 11 416 7.1E-183 T 23-10-2018 IPR004403 Peptide chain release factor eRF1/aRF1 GO:0003747|GO:0005737|GO:0006415 Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_04620 728c64c4937db1a944ee58dde14fa3c8 417 SUPERFAMILY SSF53137 141 273 3.01E-44 T 23-10-2018 A3L04_04620 728c64c4937db1a944ee58dde14fa3c8 417 Gene3D G3DSA:3.30.960.10 1 133 4.6E-55 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_04620 728c64c4937db1a944ee58dde14fa3c8 417 Gene3D G3DSA:3.30.420.60 134 274 4.7E-54 T 23-10-2018 A3L04_04620 728c64c4937db1a944ee58dde14fa3c8 417 SUPERFAMILY SSF55481 5 138 1.44E-50 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_04680 17ef2085286548b6521ca46fb64455c8 330 Pfam PF01343 Peptidase family S49 147 294 1.4E-41 T 23-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 A3L04_04680 17ef2085286548b6521ca46fb64455c8 330 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 88 292 6.4E-73 T 23-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 A3L04_04680 17ef2085286548b6521ca46fb64455c8 330 Gene3D G3DSA:3.40.1750.20 185 251 4.4E-57 T 23-10-2018 A3L04_04680 17ef2085286548b6521ca46fb64455c8 330 Gene3D G3DSA:3.90.226.10 90 286 4.4E-57 T 23-10-2018 A3L04_04680 17ef2085286548b6521ca46fb64455c8 330 SUPERFAMILY SSF52096 87 282 1.43E-36 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L04_01405 620d736097a765f608977ef82c81259c 300 Gene3D G3DSA:1.10.287.950 114 254 1.9E-5 T 23-10-2018 A3L04_09715 4c3610db9702ef3c49ea3c160f023196 134 SUPERFAMILY SSF52016 1 128 1.33E-41 T 23-10-2018 A3L04_09715 4c3610db9702ef3c49ea3c160f023196 134 Gene3D G3DSA:3.50.30.10 1 133 2.1E-46 T 23-10-2018 A3L04_09715 4c3610db9702ef3c49ea3c160f023196 134 PIRSF PIRSF004966 1 131 1.4E-52 T 23-10-2018 IPR012016 Aconitase X subunit 2, putative A3L04_09715 4c3610db9702ef3c49ea3c160f023196 134 Hamap MF_00078 UPF0107 protein . 2 129 31.988 T 23-10-2018 IPR020794 Aconitase X subunit 2, archaeal, putative A3L04_09715 4c3610db9702ef3c49ea3c160f023196 134 Pfam PF01989 Protein of unknown function DUF126 24 103 4.5E-34 T 23-10-2018 IPR002840 Aconitase X swivel domain, putative A3L04_04115 d95c6ad3a604b4fb525e173f66597056 273 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 2 263 2.9E-115 T 23-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 A3L04_04115 d95c6ad3a604b4fb525e173f66597056 273 Pfam PF05681 Fumarate hydratase (Fumerase) 3 262 5.6E-89 T 23-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 A3L04_06575 410cee0637bc904aaa9a52dbfac2c540 178 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 43 175 2.0E-43 T 23-10-2018 IPR005247 YbhB/YbcL A3L04_06575 410cee0637bc904aaa9a52dbfac2c540 178 Pfam PF01161 Phosphatidylethanolamine-binding protein 39 176 3.1E-39 T 23-10-2018 IPR008914 Phosphatidylethanolamine-binding protein A3L04_06575 410cee0637bc904aaa9a52dbfac2c540 178 SUPERFAMILY SSF49777 30 178 1.18E-48 T 23-10-2018 IPR036610 PEBP-like superfamily A3L04_06575 410cee0637bc904aaa9a52dbfac2c540 178 Gene3D G3DSA:3.90.280.10 20 178 1.9E-57 T 23-10-2018 IPR036610 PEBP-like superfamily A3L04_03975 3b39cfe87f0160488227b108d725305d 138 SMART SM00670 5 113 1.5E-13 T 23-10-2018 IPR002716 PIN domain A3L04_03975 3b39cfe87f0160488227b108d725305d 138 Pfam PF04900 Fcf1 31 129 4.0E-5 T 23-10-2018 IPR006984 rRNA-processing protein Fcf1/Utp23 GO:0032040 A3L04_03975 3b39cfe87f0160488227b108d725305d 138 SUPERFAMILY SSF88723 5 130 1.18E-21 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_03975 3b39cfe87f0160488227b108d725305d 138 Gene3D G3DSA:3.40.50.1010 3 136 9.4E-27 T 23-10-2018 A3L04_05175 880e7122d1e6dea08236f7d230178094 326 SUPERFAMILY SSF161098 101 307 2.45E-17 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_05175 880e7122d1e6dea08236f7d230178094 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 324 8.4E-41 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L04_05175 880e7122d1e6dea08236f7d230178094 326 Gene3D G3DSA:1.10.3720.10 92 318 5.1E-19 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_01960 c20cc7c83c5b67d9a9f06a068d09501b 385 Pfam PF01189 16S rRNA methyltransferase RsmB/F 192 381 1.2E-57 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L04_01960 c20cc7c83c5b67d9a9f06a068d09501b 385 Gene3D G3DSA:3.30.70.3130 2 81 2.9E-12 T 23-10-2018 A3L04_01960 c20cc7c83c5b67d9a9f06a068d09501b 385 Gene3D G3DSA:3.40.50.150 188 385 1.2E-64 T 23-10-2018 A3L04_01960 c20cc7c83c5b67d9a9f06a068d09501b 385 SUPERFAMILY SSF53335 6 383 3.16E-60 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_01960 c20cc7c83c5b67d9a9f06a068d09501b 385 SUPERFAMILY SSF88697 89 160 1.71E-18 T 23-10-2018 IPR015947 PUA-like superfamily A3L04_01960 c20cc7c83c5b67d9a9f06a068d09501b 385 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 203 213 7.5E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_01960 c20cc7c83c5b67d9a9f06a068d09501b 385 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 174 188 7.5E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_01960 c20cc7c83c5b67d9a9f06a068d09501b 385 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 365 382 7.5E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_01960 c20cc7c83c5b67d9a9f06a068d09501b 385 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 269 281 7.5E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_01960 c20cc7c83c5b67d9a9f06a068d09501b 385 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 316 332 7.5E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_01960 c20cc7c83c5b67d9a9f06a068d09501b 385 Pfam PF01472 PUA domain 90 159 1.7E-18 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L04_01960 c20cc7c83c5b67d9a9f06a068d09501b 385 SMART SM00359 90 164 2.3E-22 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L04_01960 c20cc7c83c5b67d9a9f06a068d09501b 385 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 85 159 1.5E-8 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L04_01960 c20cc7c83c5b67d9a9f06a068d09501b 385 Gene3D G3DSA:2.30.130.70 82 168 1.5E-18 T 23-10-2018 A3L04_01960 c20cc7c83c5b67d9a9f06a068d09501b 385 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 168 382 2.5E-65 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L04_06025 f0bcdc75761c4c9efbb86ecef23f9121 120 TIGRFAM TIGR04076 TIGR04076: TIGR04076 family protein 1 96 1.2E-21 T 23-10-2018 IPR023811 Conserved hypothetical protein CHP04076 A3L04_02430 eae978798220184205ab8580291b4f3e 395 Pfam PF00155 Aminotransferase class I and II 40 383 1.3E-72 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L04_02430 eae978798220184205ab8580291b4f3e 395 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 238 247 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A3L04_02430 eae978798220184205ab8580291b4f3e 395 Gene3D G3DSA:3.40.640.10 55 291 4.6E-143 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L04_02430 eae978798220184205ab8580291b4f3e 395 SUPERFAMILY SSF53383 4 391 9.25E-122 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L04_02430 eae978798220184205ab8580291b4f3e 395 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 7 394 1.8E-208 T 23-10-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type A3L04_02430 eae978798220184205ab8580291b4f3e 395 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 23 384 3.5E-130 T 23-10-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 A3L04_02430 eae978798220184205ab8580291b4f3e 395 Gene3D G3DSA:3.90.1150.10 35 385 4.6E-143 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L04_10790 ef8a5ef96f5849a40d3d5b79739e62f9 332 Gene3D G3DSA:3.40.630.10 8 325 1.2E-121 T 23-10-2018 A3L04_10790 ef8a5ef96f5849a40d3d5b79739e62f9 332 SUPERFAMILY SSF53187 1 330 4.11E-57 T 23-10-2018 A3L04_10790 ef8a5ef96f5849a40d3d5b79739e62f9 332 Pfam PF05343 M42 glutamyl aminopeptidase 43 324 3.0E-90 T 23-10-2018 IPR008007 Peptidase M42 A3L04_10790 ef8a5ef96f5849a40d3d5b79739e62f9 332 PIRSF PIRSF001123 1 332 1.5E-95 T 23-10-2018 IPR008007 Peptidase M42 A3L04_10790 ef8a5ef96f5849a40d3d5b79739e62f9 332 Gene3D G3DSA:2.40.30.40 65 156 1.2E-121 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A3L04_10790 ef8a5ef96f5849a40d3d5b79739e62f9 332 SUPERFAMILY SSF101821 66 173 1.16E-22 T 23-10-2018 A3L04_03075 e23229ae9fc7a54e433a813c07b0b491 345 Pfam PF13429 Tetratricopeptide repeat 165 312 3.3E-7 T 23-10-2018 A3L04_03075 e23229ae9fc7a54e433a813c07b0b491 345 SUPERFAMILY SSF48452 130 329 7.21E-24 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L04_03075 e23229ae9fc7a54e433a813c07b0b491 345 SMART SM00028 217 250 1.2 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L04_03075 e23229ae9fc7a54e433a813c07b0b491 345 SMART SM00028 153 186 180.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L04_03075 e23229ae9fc7a54e433a813c07b0b491 345 SMART SM00028 255 288 180.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L04_03075 e23229ae9fc7a54e433a813c07b0b491 345 Gene3D G3DSA:1.25.40.10 71 335 1.1E-19 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L04_02645 c45afa9560ad51f9f315d6bab4458ff2 427 Pfam PF01943 Polysaccharide biosynthesis protein 18 284 3.2E-14 T 23-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A3L04_02340 01a5f43f351e1f2157fe34e7f225f5e5 149 Pfam PF00582 Universal stress protein family 2 149 1.9E-22 T 23-10-2018 IPR006016 UspA A3L04_02340 01a5f43f351e1f2157fe34e7f225f5e5 149 SUPERFAMILY SSF52402 2 149 6.2E-27 T 23-10-2018 A3L04_02340 01a5f43f351e1f2157fe34e7f225f5e5 149 Gene3D G3DSA:3.40.50.620 1 149 4.6E-32 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_09490 36b0910d0bad8bde732329c7798b8de6 191 Gene3D G3DSA:3.40.109.10 1 172 1.6E-48 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L04_09490 36b0910d0bad8bde732329c7798b8de6 191 SUPERFAMILY SSF55469 1 170 2.49E-43 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L04_09490 36b0910d0bad8bde732329c7798b8de6 191 Pfam PF00881 Nitroreductase family 7 61 2.6E-14 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A3L04_09490 36b0910d0bad8bde732329c7798b8de6 191 Pfam PF00881 Nitroreductase family 69 149 1.1E-5 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A3L04_07630 e0d030a2189a9e4ca4389cb262a7b520 330 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 18 321 5.4E-124 T 23-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 A3L04_07630 e0d030a2189a9e4ca4389cb262a7b520 330 SUPERFAMILY SSF51905 14 319 5.87E-63 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_07630 e0d030a2189a9e4ca4389cb262a7b520 330 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 154 174 - T 23-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 A3L04_07630 e0d030a2189a9e4ca4389cb262a7b520 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 213 229 4.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L04_07630 e0d030a2189a9e4ca4389cb262a7b520 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 285 303 4.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L04_07630 e0d030a2189a9e4ca4389cb262a7b520 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 125 133 4.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L04_07630 e0d030a2189a9e4ca4389cb262a7b520 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 51 66 4.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L04_07630 e0d030a2189a9e4ca4389cb262a7b520 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 72 82 4.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L04_07630 e0d030a2189a9e4ca4389cb262a7b520 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 19 41 4.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L04_07630 e0d030a2189a9e4ca4389cb262a7b520 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 162 186 4.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L04_07630 e0d030a2189a9e4ca4389cb262a7b520 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 147 159 4.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L04_07630 e0d030a2189a9e4ca4389cb262a7b520 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 251 272 4.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L04_07630 e0d030a2189a9e4ca4389cb262a7b520 330 Gene3D G3DSA:3.50.50.60 136 257 4.3E-116 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_07630 e0d030a2189a9e4ca4389cb262a7b520 330 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 310 3.6E-61 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L04_07630 e0d030a2189a9e4ca4389cb262a7b520 330 Gene3D G3DSA:3.50.50.60 18 315 4.3E-116 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_07630 e0d030a2189a9e4ca4389cb262a7b520 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 249 265 1.2E-42 T 23-10-2018 A3L04_07630 e0d030a2189a9e4ca4389cb262a7b520 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 1.2E-42 T 23-10-2018 A3L04_07630 e0d030a2189a9e4ca4389cb262a7b520 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 20 39 1.2E-42 T 23-10-2018 A3L04_07630 e0d030a2189a9e4ca4389cb262a7b520 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 124 142 1.2E-42 T 23-10-2018 A3L04_07630 e0d030a2189a9e4ca4389cb262a7b520 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 1.2E-42 T 23-10-2018 A3L04_03305 93f86d2dc1fa0cece4c70564c9b3a4aa 533 TIGRFAM TIGR00337 PyrG: CTP synthase 1 525 3.8E-254 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A3L04_03305 93f86d2dc1fa0cece4c70564c9b3a4aa 533 Pfam PF00117 Glutamine amidotransferase class-I 300 525 1.3E-57 T 23-10-2018 IPR017926 Glutamine amidotransferase A3L04_03305 93f86d2dc1fa0cece4c70564c9b3a4aa 533 Gene3D G3DSA:3.40.50.880 284 533 9.4E-108 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L04_03305 93f86d2dc1fa0cece4c70564c9b3a4aa 533 SUPERFAMILY SSF52540 2 266 1.76E-121 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_03305 93f86d2dc1fa0cece4c70564c9b3a4aa 533 Pfam PF06418 CTP synthase N-terminus 3 265 9.2E-128 T 23-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A3L04_03305 93f86d2dc1fa0cece4c70564c9b3a4aa 533 Hamap MF_01227 CTP synthase [pyrG]. 2 530 53.19 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A3L04_03305 93f86d2dc1fa0cece4c70564c9b3a4aa 533 Gene3D G3DSA:3.40.50.300 1 283 4.8E-141 T 23-10-2018 A3L04_03305 93f86d2dc1fa0cece4c70564c9b3a4aa 533 SUPERFAMILY SSF52317 288 532 2.29E-81 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L04_01440 4433ccef7528a3273f39caf7207feab3 242 Pfam PF09754 PAC2 family 19 222 6.3E-45 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 A3L04_01440 4433ccef7528a3273f39caf7207feab3 242 TIGRFAM TIGR00161 TIGR00161: TIGR00161 family protein 11 237 3.9E-66 T 23-10-2018 IPR004425 Conserved hypothetical protein CHP00061 A3L04_01440 4433ccef7528a3273f39caf7207feab3 242 SUPERFAMILY SSF159659 11 240 7.85E-49 T 23-10-2018 A3L04_01440 4433ccef7528a3273f39caf7207feab3 242 Gene3D G3DSA:3.40.50.10900 1 242 5.4E-72 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily A3L04_10435 c03be0f2f1b74108f74e277eafda5835 154 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 100 111 4.4E-9 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L04_10435 c03be0f2f1b74108f74e277eafda5835 154 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 38 53 4.4E-9 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L04_10435 c03be0f2f1b74108f74e277eafda5835 154 Pfam PF00717 Peptidase S24-like 38 89 4.4E-7 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A3L04_10435 c03be0f2f1b74108f74e277eafda5835 154 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 5 148 4.8E-45 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L04_10435 c03be0f2f1b74108f74e277eafda5835 154 SUPERFAMILY SSF51306 35 88 6.45E-11 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A3L04_04105 a349d370df39021a2349165fc93fe400 77 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 8 65 4.1E-19 T 23-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 A3L04_04105 a349d370df39021a2349165fc93fe400 77 SUPERFAMILY SSF54786 3 72 3.92E-17 T 23-10-2018 A3L04_04105 a349d370df39021a2349165fc93fe400 77 Gene3D G3DSA:3.30.920.30 6 72 8.0E-19 T 23-10-2018 IPR038570 HicA superfamily A3L04_05110 607b46346b0062321a874d8de8b18bef 118 Gene3D G3DSA:3.40.1230.10 1 118 1.4E-35 T 23-10-2018 IPR036748 MTH938-like superfamily A3L04_05110 607b46346b0062321a874d8de8b18bef 118 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 5 99 1.7E-9 T 23-10-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein A3L04_05110 607b46346b0062321a874d8de8b18bef 118 SUPERFAMILY SSF64076 2 118 5.23E-35 T 23-10-2018 IPR036748 MTH938-like superfamily A3L04_01975 89b12b56e176d30a8084b8ce680a54b4 324 ProSitePatterns PS01016 Glycoprotease family signature. 92 112 - T 23-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 A3L04_01975 89b12b56e176d30a8084b8ce680a54b4 324 SUPERFAMILY SSF53067 1 293 3.89E-38 T 23-10-2018 A3L04_01975 89b12b56e176d30a8084b8ce680a54b4 324 Gene3D G3DSA:3.30.420.40 4 299 1.5E-115 T 23-10-2018 A3L04_01975 89b12b56e176d30a8084b8ce680a54b4 324 Gene3D G3DSA:3.30.420.40 122 278 1.5E-115 T 23-10-2018 A3L04_01975 89b12b56e176d30a8084b8ce680a54b4 324 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 291 2.1E-102 T 23-10-2018 IPR017861 Kae1/TsaD family A3L04_01975 89b12b56e176d30a8084b8ce680a54b4 324 Pfam PF00814 Glycoprotease family 23 292 1.2E-96 T 23-10-2018 IPR000905 Gcp-like domain A3L04_01975 89b12b56e176d30a8084b8ce680a54b4 324 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 146 167 1.0E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L04_01975 89b12b56e176d30a8084b8ce680a54b4 324 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 124 136 1.0E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L04_01975 89b12b56e176d30a8084b8ce680a54b4 324 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 93 112 1.0E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L04_01975 89b12b56e176d30a8084b8ce680a54b4 324 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 72 92 1.0E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L04_01975 89b12b56e176d30a8084b8ce680a54b4 324 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 1.0E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L04_01975 89b12b56e176d30a8084b8ce680a54b4 324 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 248 257 1.0E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L04_01975 89b12b56e176d30a8084b8ce680a54b4 324 Hamap MF_01446 tRNA N6-adenosine threonylcarbamoyltransferase [kae1]. 1 324 37.192 T 23-10-2018 IPR034680 tRNA N6-adenosine threonylcarbamoyltransferase Kae1/OSGEP GO:0000408|GO:0002949 Reactome: R-HSA-6782315 A3L04_01975 89b12b56e176d30a8084b8ce680a54b4 324 TIGRFAM TIGR03722 arch_KAE1: universal archaeal protein Kae1 4 324 2.0E-153 T 23-10-2018 IPR022449 tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea GO:0000408|GO:0002949 A3L04_09835 cc6b51b9c9dd12f86936b6ebc4eead22 234 Pfam PF00491 Arginase family 44 215 9.7E-18 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L04_09835 cc6b51b9c9dd12f86936b6ebc4eead22 234 PIRSF PIRSF036979 31 229 7.1E-15 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L04_09835 cc6b51b9c9dd12f86936b6ebc4eead22 234 SUPERFAMILY SSF52768 47 221 5.4E-25 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily A3L04_09835 cc6b51b9c9dd12f86936b6ebc4eead22 234 Gene3D G3DSA:3.40.800.10 33 232 8.5E-19 T 23-10-2018 A3L04_08280 a2729c061acd2535f59a8d351fb2d510 150 SUPERFAMILY SSF102712 20 141 2.22E-23 T 23-10-2018 A3L04_08280 a2729c061acd2535f59a8d351fb2d510 150 SMART SM00232 16 143 2.3E-16 T 23-10-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 A3L04_08280 a2729c061acd2535f59a8d351fb2d510 150 Pfam PF14464 Prokaryotic homologs of the JAB domain 27 133 3.7E-17 T 23-10-2018 IPR028090 JAB domain, prokaryotic A3L04_08280 a2729c061acd2535f59a8d351fb2d510 150 Gene3D G3DSA:3.40.140.10 21 150 5.0E-28 T 23-10-2018 A3L04_07025 f41b0556bb1f3cf18d7cb662e5fa3070 728 Pfam PF13620 Carboxypeptidase regulatory-like domain 404 473 5.4E-8 T 23-10-2018 A3L04_07025 f41b0556bb1f3cf18d7cb662e5fa3070 728 SUPERFAMILY SSF49464 407 489 5.89E-10 T 23-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily A3L04_07025 f41b0556bb1f3cf18d7cb662e5fa3070 728 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 318 376 1.7E-6 T 23-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain A3L04_07025 f41b0556bb1f3cf18d7cb662e5fa3070 728 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 608 683 5.1E-19 T 23-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain A3L04_07025 f41b0556bb1f3cf18d7cb662e5fa3070 728 Gene3D G3DSA:2.60.40.1120 407 477 1.8E-9 T 23-10-2018 A3L04_09865 dc44bd5c643333756eed075c998a6d68 182 Pfam PF08279 HTH domain 140 176 9.9E-7 T 23-10-2018 IPR013196 Helix-turn-helix, type 11 A3L04_09865 dc44bd5c643333756eed075c998a6d68 182 Gene3D G3DSA:1.10.10.10 118 181 9.5E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_09865 dc44bd5c643333756eed075c998a6d68 182 SUPERFAMILY SSF46785 136 176 1.85E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_00340 44ca42b8f13b295b810cd3fcb510f2ef 293 SMART SM00382 28 210 3.3E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_00340 44ca42b8f13b295b810cd3fcb510f2ef 293 Pfam PF13732 Domain of unknown function (DUF4162) 207 288 7.3E-8 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 A3L04_00340 44ca42b8f13b295b810cd3fcb510f2ef 293 SUPERFAMILY SSF52540 3 214 3.65E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_00340 44ca42b8f13b295b810cd3fcb510f2ef 293 Gene3D G3DSA:3.40.50.300 1 229 3.7E-66 T 23-10-2018 A3L04_00340 44ca42b8f13b295b810cd3fcb510f2ef 293 Pfam PF00005 ABC transporter 19 153 3.4E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_09645 d956208b98b7c2a95cceb0d47334e63a 193 Pfam PF12389 Camelysin metallo-endopeptidase 1 98 1.0E-6 T 23-10-2018 IPR022121 Peptidase M73, camelysin A3L04_07810 5d167e344f617afeca0f5384dbd2e850 239 SUPERFAMILY SSF47413 23 75 4.86E-12 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L04_07810 5d167e344f617afeca0f5384dbd2e850 239 SMART SM00530 26 81 1.3E-12 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L04_07810 5d167e344f617afeca0f5384dbd2e850 239 Pfam PF01381 Helix-turn-helix 28 75 3.5E-9 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L04_07810 5d167e344f617afeca0f5384dbd2e850 239 PIRSF PIRSF037724 1 236 2.8E-106 T 23-10-2018 IPR017271 Transcription regulator HTH, MJ1545, predicted A3L04_07810 5d167e344f617afeca0f5384dbd2e850 239 Gene3D G3DSA:1.10.260.40 24 80 6.0E-11 T 23-10-2018 A3L04_05905 175f37da34f7f16dfa89f9c4837bf7d4 134 SUPERFAMILY SSF50249 8 116 9.42E-33 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_05905 175f37da34f7f16dfa89f9c4837bf7d4 134 Gene3D G3DSA:1.10.12.20 2 49 4.8E-6 T 23-10-2018 A3L04_05905 175f37da34f7f16dfa89f9c4837bf7d4 134 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 50 112 5.4E-21 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal A3L04_05905 175f37da34f7f16dfa89f9c4837bf7d4 134 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 17 47 5.1E-11 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal A3L04_08915 727dbb8ea9e0da4152e76771e820df2c 76 Gene3D G3DSA:2.10.260.10 1 40 3.3E-15 T 23-10-2018 A3L04_08915 727dbb8ea9e0da4152e76771e820df2c 76 SUPERFAMILY SSF89447 2 45 2.09E-12 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L04_08915 727dbb8ea9e0da4152e76771e820df2c 76 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 2 41 9.9E-17 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L04_08915 727dbb8ea9e0da4152e76771e820df2c 76 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 3 36 7.6E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L04_08915 727dbb8ea9e0da4152e76771e820df2c 76 SMART SM00966 2 47 3.7E-14 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L04_02850 7c9cce40d1be431afca2660b78fa4ec9 368 Gene3D G3DSA:3.40.50.2300 5 145 4.5E-39 T 23-10-2018 A3L04_02850 7c9cce40d1be431afca2660b78fa4ec9 368 SUPERFAMILY SSF52738 165 350 8.63E-66 T 23-10-2018 IPR035909 Methylesterase CheB, C-terminal A3L04_02850 7c9cce40d1be431afca2660b78fa4ec9 368 SMART SM00448 8 122 2.0E-30 T 23-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A3L04_02850 7c9cce40d1be431afca2660b78fa4ec9 368 SUPERFAMILY SSF52172 6 115 2.13E-32 T 23-10-2018 IPR011006 CheY-like superfamily A3L04_02850 7c9cce40d1be431afca2660b78fa4ec9 368 Pfam PF01339 CheB methylesterase 168 346 2.3E-61 T 23-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A3L04_02850 7c9cce40d1be431afca2660b78fa4ec9 368 Pfam PF00072 Response regulator receiver domain 10 114 6.0E-27 T 23-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A3L04_02850 7c9cce40d1be431afca2660b78fa4ec9 368 PIRSF PIRSF000876 5 355 1.5E-142 T 23-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A3L04_02850 7c9cce40d1be431afca2660b78fa4ec9 368 Gene3D G3DSA:3.40.50.180 146 351 1.2E-72 T 23-10-2018 IPR035909 Methylesterase CheB, C-terminal A3L04_02850 7c9cce40d1be431afca2660b78fa4ec9 368 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 8 352 41.588 T 23-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A3L04_08270 57197712daca0d35032d556075a8750d 136 Pfam PF01022 Bacterial regulatory protein, arsR family 60 106 4.1E-13 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_08270 57197712daca0d35032d556075a8750d 136 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 2.9E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_08270 57197712daca0d35032d556075a8750d 136 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 87 102 2.9E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_08270 57197712daca0d35032d556075a8750d 136 Gene3D G3DSA:1.10.10.10 37 124 1.8E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_08270 57197712daca0d35032d556075a8750d 136 SMART SM00418 53 131 1.4E-11 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_08270 57197712daca0d35032d556075a8750d 136 SUPERFAMILY SSF46785 47 120 2.29E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_06260 3e8d82654792071b7904f8133dcbba90 420 Gene3D G3DSA:3.20.20.110 129 420 7.1E-133 T 23-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L04_06260 3e8d82654792071b7904f8133dcbba90 420 SUPERFAMILY SSF54966 4 128 4.71E-40 T 23-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L04_06260 3e8d82654792071b7904f8133dcbba90 420 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 8 124 1.0E-40 T 23-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L04_06260 3e8d82654792071b7904f8133dcbba90 420 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 134 414 1.3E-92 T 23-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L04_06260 3e8d82654792071b7904f8133dcbba90 420 SUPERFAMILY SSF51649 128 418 6.67E-111 T 23-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L04_06260 3e8d82654792071b7904f8133dcbba90 420 TIGRFAM TIGR03326 rubisco_III: ribulose bisphosphate carboxylase, type III 8 414 7.3E-206 T 23-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L04_06260 3e8d82654792071b7904f8133dcbba90 420 Hamap MF_01133 Ribulose bisphosphate carboxylase [rbcL]. 7 415 50.201 T 23-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L04_06260 3e8d82654792071b7904f8133dcbba90 420 Gene3D G3DSA:3.30.70.150 1 128 8.1E-45 T 23-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L04_10360 41d6ac6ce0d123d0c691eb160c042e7a 59 ProDom PD256538 PF0630 PYRAB06030 AF2407.1 3 59 4.0E-27 T 23-10-2018 IPR020199 Uncharacterised protein family PYRAB06030 A3L04_04025 d169c8acb418821479d273279b3892de 361 Gene3D G3DSA:2.160.10.10 246 360 3.0E-17 T 23-10-2018 A3L04_04025 d169c8acb418821479d273279b3892de 361 SUPERFAMILY SSF53448 1 303 6.07E-82 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_04025 d169c8acb418821479d273279b3892de 361 SUPERFAMILY SSF51161 199 355 1.8E-24 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A3L04_04025 d169c8acb418821479d273279b3892de 361 Pfam PF00483 Nucleotidyl transferase 2 232 3.9E-52 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L04_04025 d169c8acb418821479d273279b3892de 361 Gene3D G3DSA:3.90.550.10 1 243 2.1E-79 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_04025 d169c8acb418821479d273279b3892de 361 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 256 293 7.4E-8 T 23-10-2018 IPR001451 Hexapeptide repeat A3L04_04025 d169c8acb418821479d273279b3892de 361 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 308 341 9.9E-9 T 23-10-2018 IPR001451 Hexapeptide repeat A3L04_02920 71631ecc863acaaa238a14c9cf30b21a 483 Pfam PF00232 Glycosyl hydrolase family 1 122 480 1.1E-51 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L04_02920 71631ecc863acaaa238a14c9cf30b21a 483 Pfam PF00232 Glycosyl hydrolase family 1 2 105 1.0E-9 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L04_02920 71631ecc863acaaa238a14c9cf30b21a 483 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 394 402 - T 23-10-2018 IPR018120 Glycoside hydrolase family 1, active site A3L04_02920 71631ecc863acaaa238a14c9cf30b21a 483 SUPERFAMILY SSF51445 2 481 2.45E-124 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L04_02920 71631ecc863acaaa238a14c9cf30b21a 483 Gene3D G3DSA:3.20.20.80 1 483 1.0E-133 T 23-10-2018 A3L04_02920 71631ecc863acaaa238a14c9cf30b21a 483 PRINTS PR00131 Glycosyl hydrolase family 1 signature 406 417 5.2E-17 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L04_02920 71631ecc863acaaa238a14c9cf30b21a 483 PRINTS PR00131 Glycosyl hydrolase family 1 signature 451 463 5.2E-17 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L04_02920 71631ecc863acaaa238a14c9cf30b21a 483 PRINTS PR00131 Glycosyl hydrolase family 1 signature 394 402 5.2E-17 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L04_02920 71631ecc863acaaa238a14c9cf30b21a 483 PRINTS PR00131 Glycosyl hydrolase family 1 signature 427 444 5.2E-17 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L04_02920 71631ecc863acaaa238a14c9cf30b21a 483 PRINTS PR00131 Glycosyl hydrolase family 1 signature 317 331 5.2E-17 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L04_07680 446dc12c9fa0104e9f489fba13a10b53 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 325 2.6E-32 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L04_07680 446dc12c9fa0104e9f489fba13a10b53 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 305 1.9E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L04_07680 446dc12c9fa0104e9f489fba13a10b53 326 Gene3D G3DSA:3.40.50.300 3 326 1.2E-100 T 23-10-2018 A3L04_07680 446dc12c9fa0104e9f489fba13a10b53 326 SUPERFAMILY SSF52540 34 323 4.17E-65 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_07680 446dc12c9fa0104e9f489fba13a10b53 326 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_07680 446dc12c9fa0104e9f489fba13a10b53 326 Pfam PF00005 ABC transporter 26 189 2.9E-25 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_07680 446dc12c9fa0104e9f489fba13a10b53 326 SMART SM00382 34 247 6.4E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_06535 93e2a749aa64f249cc9f7dd1c423b491 248 Gene3D G3DSA:3.20.20.410 1 238 1.5E-41 T 23-10-2018 IPR036520 UPF0759 superfamily A3L04_06535 93e2a749aa64f249cc9f7dd1c423b491 248 SUPERFAMILY SSF117396 1 237 1.57E-46 T 23-10-2018 IPR036520 UPF0759 superfamily A3L04_06535 93e2a749aa64f249cc9f7dd1c423b491 248 Pfam PF01904 Protein of unknown function DUF72 14 234 4.6E-36 T 23-10-2018 IPR002763 Protein of unknown function DUF72 A3L04_00065 f2d66dd8e2cf52acc1cb6a1aeddc4398 265 SUPERFAMILY SSF46785 4 97 1.99E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_00065 f2d66dd8e2cf52acc1cb6a1aeddc4398 265 Gene3D G3DSA:1.10.10.10 6 103 1.0E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_00065 f2d66dd8e2cf52acc1cb6a1aeddc4398 265 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 15 80 2.9E-26 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L04_02290 96414b4ac400f9574ebb3662f5c3d11c 278 Hamap MF_00583_A Putative ribose-phosphate pyrophosphokinase [prs]. 1 277 37.055 T 23-10-2018 IPR037514 Ribose-phosphate pyrophosphokinase, archaea GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A3L04_02290 96414b4ac400f9574ebb3662f5c3d11c 278 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 2 276 2.2E-93 T 23-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A3L04_02290 96414b4ac400f9574ebb3662f5c3d11c 278 Gene3D G3DSA:3.40.50.2020 143 270 5.1E-42 T 23-10-2018 A3L04_02290 96414b4ac400f9574ebb3662f5c3d11c 278 SMART SM01400 1 109 3.6E-32 T 23-10-2018 A3L04_02290 96414b4ac400f9574ebb3662f5c3d11c 278 SUPERFAMILY SSF53271 61 269 5.23E-37 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L04_02290 96414b4ac400f9574ebb3662f5c3d11c 278 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 9 108 5.9E-21 T 23-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A3L04_02290 96414b4ac400f9574ebb3662f5c3d11c 278 Gene3D G3DSA:3.40.50.2020 1 142 1.0E-38 T 23-10-2018 A3L04_02290 96414b4ac400f9574ebb3662f5c3d11c 278 Pfam PF00156 Phosphoribosyl transferase domain 140 238 2.3E-17 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L04_08695 8badc708594bc149805daf72496084eb 394 Gene3D G3DSA:3.90.550.10 1 394 3.8E-162 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_08695 8badc708594bc149805daf72496084eb 394 TIGRFAM TIGR02460 osmo_MPGsynth: mannosyl-3-phosphoglycerate synthase 2 383 6.9E-196 T 23-10-2018 IPR012812 Mannosyl-3-phosphoglycerate synthase GO:0005737|GO:0050504|GO:0051479 KEGG: 00051+2.4.1.217|MetaCyc: PWY-5656 A3L04_08695 8badc708594bc149805daf72496084eb 394 SUPERFAMILY SSF53448 51 206 3.19E-7 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_08695 8badc708594bc149805daf72496084eb 394 Pfam PF09488 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) 7 380 4.5E-157 T 23-10-2018 IPR012812 Mannosyl-3-phosphoglycerate synthase GO:0005737|GO:0050504|GO:0051479 KEGG: 00051+2.4.1.217|MetaCyc: PWY-5656 A3L04_03235 87458b20b6d6b08d82e96f370f3668fd 408 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 340 347 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L04_03235 87458b20b6d6b08d82e96f370f3668fd 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 225 250 2.3E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L04_03235 87458b20b6d6b08d82e96f370f3668fd 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 276 302 2.3E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L04_03235 87458b20b6d6b08d82e96f370f3668fd 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 64 85 2.3E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L04_03235 87458b20b6d6b08d82e96f370f3668fd 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 95 115 2.3E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L04_03235 87458b20b6d6b08d82e96f370f3668fd 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 328 349 2.3E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L04_03235 87458b20b6d6b08d82e96f370f3668fd 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 185 203 2.3E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L04_03235 87458b20b6d6b08d82e96f370f3668fd 408 Gene3D G3DSA:1.10.3270.10 1 74 3.1E-7 T 23-10-2018 IPR023282 Hydroxymethylglutaryl-CoA reductase, N-terminal GO:0004420 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L04_03235 87458b20b6d6b08d82e96f370f3668fd 408 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 187 201 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L04_03235 87458b20b6d6b08d82e96f370f3668fd 408 SUPERFAMILY SSF56542 4 398 1.83E-92 T 23-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L04_03235 87458b20b6d6b08d82e96f370f3668fd 408 Gene3D G3DSA:3.90.770.10 75 395 2.2E-131 T 23-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L04_03235 87458b20b6d6b08d82e96f370f3668fd 408 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 32 408 1.5E-138 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L04_03235 87458b20b6d6b08d82e96f370f3668fd 408 TIGRFAM TIGR00533 HMG_CoA_R_NADP: hydroxymethylglutaryl-CoA reductase (NADPH) 1 408 2.5E-166 T 23-10-2018 IPR004554 Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type GO:0004420|GO:0008299|GO:0016021|GO:0050661|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L04_03235 87458b20b6d6b08d82e96f370f3668fd 408 Gene3D G3DSA:3.30.70.420 129 244 2.2E-131 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L04_03235 87458b20b6d6b08d82e96f370f3668fd 408 SUPERFAMILY SSF55035 129 244 7.06E-41 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L04_04985 601dbf20496a0558ef6c3a05c4abfe8e 455 SUPERFAMILY SSF48371 28 432 4.61E-34 T 23-10-2018 IPR016024 Armadillo-type fold A3L04_04985 601dbf20496a0558ef6c3a05c4abfe8e 455 Gene3D G3DSA:1.25.10.10 18 249 9.3E-14 T 23-10-2018 IPR011989 Armadillo-like helical A3L04_04985 601dbf20496a0558ef6c3a05c4abfe8e 455 Gene3D G3DSA:1.25.10.10 250 432 2.1E-6 T 23-10-2018 IPR011989 Armadillo-like helical A3L04_06145 ecfadd8e0dfacd69d4a0e5612fb0e1f5 451 Gene3D G3DSA:3.40.50.720 4 133 1.5E-8 T 23-10-2018 A3L04_06145 ecfadd8e0dfacd69d4a0e5612fb0e1f5 451 SUPERFAMILY SSF52540 126 296 3.34E-11 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_06145 ecfadd8e0dfacd69d4a0e5612fb0e1f5 451 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 240 300 1.4E-4 T 23-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain A3L04_06145 ecfadd8e0dfacd69d4a0e5612fb0e1f5 451 Gene3D G3DSA:3.40.50.300 212 307 1.3E-7 T 23-10-2018 A3L04_04305 b3e412c8c8027bd7674804d9e0f81958 454 Hamap MF_00561 ADP-specific phosphofructokinase [pfkC]. 2 452 43.384 T 23-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 A3L04_04305 b3e412c8c8027bd7674804d9e0f81958 454 Gene3D G3DSA:3.40.1190.20 11 443 5.1E-169 T 23-10-2018 IPR029056 Ribokinase-like A3L04_04305 b3e412c8c8027bd7674804d9e0f81958 454 SUPERFAMILY SSF53613 8 451 1.25E-158 T 23-10-2018 IPR029056 Ribokinase-like A3L04_04305 b3e412c8c8027bd7674804d9e0f81958 454 Gene3D G3DSA:3.30.1110.20 16 194 5.1E-169 T 23-10-2018 A3L04_04305 b3e412c8c8027bd7674804d9e0f81958 454 TIGRFAM TIGR02045 P_fruct_ADP: ADP-specific phosphofructokinase 10 452 2.6E-228 T 23-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 A3L04_04305 b3e412c8c8027bd7674804d9e0f81958 454 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 11 443 7.0E-109 T 23-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 A3L04_04305 b3e412c8c8027bd7674804d9e0f81958 454 PIRSF PIRSF015883 1 452 9.8E-201 T 23-10-2018 IPR015990 ADP-specific phosphofructokinase/glucokinase, archaeal GO:0000287|GO:0006096|GO:0016773 A3L04_09515 c3250cb55b1bf173411ab5d8b69378bd 359 SUPERFAMILY SSF52540 2 257 1.35E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09515 c3250cb55b1bf173411ab5d8b69378bd 359 SUPERFAMILY SSF46785 285 356 9.67E-19 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_09515 c3250cb55b1bf173411ab5d8b69378bd 359 Pfam PF01637 ATPase domain predominantly from Archaea 14 247 9.5E-17 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_09515 c3250cb55b1bf173411ab5d8b69378bd 359 Gene3D G3DSA:1.10.8.60 207 282 4.5E-24 T 23-10-2018 A3L04_09515 c3250cb55b1bf173411ab5d8b69378bd 359 Gene3D G3DSA:1.10.10.10 287 357 1.0E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_09515 c3250cb55b1bf173411ab5d8b69378bd 359 Gene3D G3DSA:3.40.50.300 1 205 1.5E-42 T 23-10-2018 A3L04_10470 d9e87b0409583113cf8e155dcd411d05 334 SUPERFAMILY SSF51735 103 290 1.48E-66 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_10470 d9e87b0409583113cf8e155dcd411d05 334 Gene3D G3DSA:3.40.50.720 4 317 8.6E-144 T 23-10-2018 A3L04_10470 d9e87b0409583113cf8e155dcd411d05 334 SUPERFAMILY SSF52283 2 133 1.21E-41 T 23-10-2018 A3L04_10470 d9e87b0409583113cf8e155dcd411d05 334 Gene3D G3DSA:3.40.50.720 98 290 8.6E-144 T 23-10-2018 A3L04_10470 d9e87b0409583113cf8e155dcd411d05 334 Hamap MF_00776 Glyoxylate reductase [gyaR]. 1 331 61.288 T 23-10-2018 IPR023519 Glyoxylate reductase GyaR GO:0047964|GO:0055114 KEGG: 00630+1.1.1.26|MetaCyc: PWY-7294|MetaCyc: PWY-7295 A3L04_10470 d9e87b0409583113cf8e155dcd411d05 334 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 322 6.5E-38 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A3L04_10470 d9e87b0409583113cf8e155dcd411d05 334 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 153 180 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A3L04_10470 d9e87b0409583113cf8e155dcd411d05 334 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 290 7.6E-70 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A3L04_10470 d9e87b0409583113cf8e155dcd411d05 334 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 230 246 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A3L04_01645 9d10f0bf1237dfd0fd8692f7010d1a09 389 SUPERFAMILY SSF140914 2 237 1.31E-33 T 23-10-2018 A3L04_01645 9d10f0bf1237dfd0fd8692f7010d1a09 389 Gene3D G3DSA:1.20.930.50 6 217 6.2E-99 T 23-10-2018 A3L04_01645 9d10f0bf1237dfd0fd8692f7010d1a09 389 Hamap MF_00701 DNA primase large subunit PriL [priL]. 1 376 29.643 T 23-10-2018 IPR023642 DNA primase large subunit PriL GO:0003896 A3L04_01645 9d10f0bf1237dfd0fd8692f7010d1a09 389 Gene3D G3DSA:2.20.20.80 108 161 6.2E-99 T 23-10-2018 A3L04_01645 9d10f0bf1237dfd0fd8692f7010d1a09 389 Pfam PF04104 Eukaryotic and archaeal DNA primase, large subunit 132 356 1.1E-33 T 23-10-2018 IPR007238 DNA primase large subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 A3L04_05995 d2fc37bd3743b9868493a7bfc437360a 348 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 66 80 - T 23-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A3L04_05995 d2fc37bd3743b9868493a7bfc437360a 348 Gene3D G3DSA:3.90.180.10 21 338 1.2E-135 T 23-10-2018 A3L04_05995 d2fc37bd3743b9868493a7bfc437360a 348 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 7 346 1.4E-188 T 23-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 A3L04_05995 d2fc37bd3743b9868493a7bfc437360a 348 Pfam PF00107 Zinc-binding dehydrogenase 178 306 1.8E-31 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A3L04_05995 d2fc37bd3743b9868493a7bfc437360a 348 Gene3D G3DSA:3.40.50.720 157 291 1.2E-135 T 23-10-2018 A3L04_05995 d2fc37bd3743b9868493a7bfc437360a 348 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 5 347 55.25 T 23-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 A3L04_05995 d2fc37bd3743b9868493a7bfc437360a 348 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 138 4.3E-37 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A3L04_05995 d2fc37bd3743b9868493a7bfc437360a 348 SUPERFAMILY SSF50129 3 177 1.02E-55 T 23-10-2018 IPR011032 GroES-like superfamily A3L04_05995 d2fc37bd3743b9868493a7bfc437360a 348 SUPERFAMILY SSF51735 146 310 1.24E-36 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_05995 d2fc37bd3743b9868493a7bfc437360a 348 SMART SM00829 16 345 6.1E-8 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A3L04_09565 4bf9431dfaca5d40e1dd3e1748bf8450 374 Gene3D G3DSA:3.40.50.20 2 105 4.5E-39 T 23-10-2018 A3L04_09565 4bf9431dfaca5d40e1dd3e1748bf8450 374 Pfam PF02222 ATP-grasp domain 109 274 4.7E-52 T 23-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type A3L04_09565 4bf9431dfaca5d40e1dd3e1748bf8450 374 SUPERFAMILY SSF56059 100 293 1.02E-56 T 23-10-2018 A3L04_09565 4bf9431dfaca5d40e1dd3e1748bf8450 374 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 3 353 42.005 T 23-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 A3L04_09565 4bf9431dfaca5d40e1dd3e1748bf8450 374 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 4 355 1.1E-133 T 23-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 A3L04_09565 4bf9431dfaca5d40e1dd3e1748bf8450 374 SUPERFAMILY SSF52440 2 97 5.61E-29 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L04_09565 4bf9431dfaca5d40e1dd3e1748bf8450 374 Gene3D G3DSA:3.30.470.20 176 366 2.3E-79 T 23-10-2018 A3L04_09565 4bf9431dfaca5d40e1dd3e1748bf8450 374 Gene3D G3DSA:3.30.1490.20 106 175 6.8E-18 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L04_09565 4bf9431dfaca5d40e1dd3e1748bf8450 374 SUPERFAMILY SSF51246 299 369 5.89E-18 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A3L04_06040 0a40ebd8601f02d8c56a42600ca3ca49 345 Gene3D G3DSA:1.20.1740.10 1 338 6.6E-9 T 23-10-2018 A3L04_06040 0a40ebd8601f02d8c56a42600ca3ca49 345 Pfam PF03222 Tryptophan/tyrosine permease family 6 333 2.0E-32 T 23-10-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 A3L04_00850 e787d079c3ed87c580fc7934226cc348 132 Gene3D G3DSA:1.10.10.10 12 125 1.6E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_00850 e787d079c3ed87c580fc7934226cc348 132 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 78 93 3.7E-16 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_00850 e787d079c3ed87c580fc7934226cc348 132 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 93 108 3.7E-16 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_00850 e787d079c3ed87c580fc7934226cc348 132 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 76 3.7E-16 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_00850 e787d079c3ed87c580fc7934226cc348 132 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 3.7E-16 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_00850 e787d079c3ed87c580fc7934226cc348 132 SUPERFAMILY SSF46785 37 123 1.14E-21 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_00850 e787d079c3ed87c580fc7934226cc348 132 SMART SM00418 44 122 7.4E-31 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_00850 e787d079c3ed87c580fc7934226cc348 132 Pfam PF01022 Bacterial regulatory protein, arsR family 51 96 2.4E-14 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_09635 005c9d4537588da82036c9c95d6f8a1e 348 SUPERFAMILY SSF50182 175 239 4.25E-18 T 23-10-2018 IPR010920 LSM domain superfamily A3L04_09635 005c9d4537588da82036c9c95d6f8a1e 348 Gene3D G3DSA:2.30.30.60 190 239 3.6E-14 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily A3L04_09635 005c9d4537588da82036c9c95d6f8a1e 348 Pfam PF00924 Mechanosensitive ion channel 130 329 1.8E-59 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A3L04_09635 005c9d4537588da82036c9c95d6f8a1e 348 Gene3D G3DSA:3.30.70.100 241 333 1.8E-31 T 23-10-2018 A3L04_09635 005c9d4537588da82036c9c95d6f8a1e 348 SUPERFAMILY SSF82861 96 173 3.66E-5 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A3L04_09635 005c9d4537588da82036c9c95d6f8a1e 348 SUPERFAMILY SSF82689 243 339 1.57E-33 T 23-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A3L04_09635 005c9d4537588da82036c9c95d6f8a1e 348 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 204 238 - T 23-10-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 A3L04_04585 67d5f16b29e64597632e753955ee4eb8 173 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 121 2.7E-9 T 23-10-2018 IPR001451 Hexapeptide repeat A3L04_04585 67d5f16b29e64597632e753955ee4eb8 173 Gene3D G3DSA:2.160.10.10 1 173 1.1E-63 T 23-10-2018 A3L04_04585 67d5f16b29e64597632e753955ee4eb8 173 SUPERFAMILY SSF51161 4 169 9.29E-52 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A3L04_02065 12424bef985befd3e126890227bd5011 246 PIRSF PIRSF006816 1 233 2.3E-76 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L04_02065 12424bef985befd3e126890227bd5011 246 Pfam PF00175 Oxidoreductase NAD-binding domain 94 181 1.0E-4 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A3L04_02065 12424bef985befd3e126890227bd5011 246 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 2 229 33.952 T 23-10-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit A3L04_02065 12424bef985befd3e126890227bd5011 246 SUPERFAMILY SSF63380 4 85 1.59E-18 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L04_02065 12424bef985befd3e126890227bd5011 246 Pfam PF00970 Oxidoreductase FAD-binding domain 5 83 5.1E-5 T 23-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A3L04_02065 12424bef985befd3e126890227bd5011 246 Gene3D G3DSA:2.40.30.10 3 84 2.5E-12 T 23-10-2018 A3L04_02065 12424bef985befd3e126890227bd5011 246 SUPERFAMILY SSF52343 80 227 2.23E-29 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L04_02065 12424bef985befd3e126890227bd5011 246 Gene3D G3DSA:3.40.50.80 87 194 1.1E-23 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L04_02065 12424bef985befd3e126890227bd5011 246 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 195 227 5.8E-11 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L04_08790 b094c2e1b022197a2e28edfc00ad929f 369 SUPERFAMILY SSF51395 28 360 9.94E-82 T 23-10-2018 A3L04_08790 b094c2e1b022197a2e28edfc00ad929f 369 Pfam PF01070 FMN-dependent dehydrogenase 182 342 1.3E-19 T 23-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 A3L04_08790 b094c2e1b022197a2e28edfc00ad929f 369 Pfam PF01070 FMN-dependent dehydrogenase 10 101 1.1E-7 T 23-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 A3L04_08790 b094c2e1b022197a2e28edfc00ad929f 369 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 9 348 7.1E-134 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A3L04_08790 b094c2e1b022197a2e28edfc00ad929f 369 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 6 349 40.857 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A3L04_08790 b094c2e1b022197a2e28edfc00ad929f 369 Gene3D G3DSA:3.20.20.70 6 367 2.6E-126 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_08790 b094c2e1b022197a2e28edfc00ad929f 369 PIRSF PIRSF003314 3 359 3.6E-135 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A3L04_00795 01066484c3856b853b71fef6063220f3 332 Gene3D G3DSA:3.40.50.1100 53 156 2.1E-120 T 23-10-2018 A3L04_00795 01066484c3856b853b71fef6063220f3 332 Gene3D G3DSA:3.40.50.1100 14 317 2.1E-120 T 23-10-2018 A3L04_00795 01066484c3856b853b71fef6063220f3 332 PIRSF PIRSF006278 2 330 1.7E-85 T 23-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase A3L04_00795 01066484c3856b853b71fef6063220f3 332 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 19 313 6.4E-43 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L04_00795 01066484c3856b853b71fef6063220f3 332 SUPERFAMILY SSF53686 10 321 5.21E-77 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L04_00795 01066484c3856b853b71fef6063220f3 332 TIGRFAM TIGR01275 ACC_deam_rel: pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family 15 324 7.4E-122 T 23-10-2018 IPR005966 D-cysteine desulfhydrase GO:0003824 KEGG: 00270+4.4.1.15 A3L04_04615 b3a4c3efbfbf2002a143887c1ea55231 284 Pfam PF00535 Glycosyl transferase family 2 64 190 4.5E-27 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L04_04615 b3a4c3efbfbf2002a143887c1ea55231 284 SUPERFAMILY SSF53448 63 278 1.45E-36 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_04615 b3a4c3efbfbf2002a143887c1ea55231 284 Gene3D G3DSA:3.90.550.10 62 283 3.8E-47 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_03165 4fbf7c619ffbbe2baa6990533bc25936 346 Gene3D G3DSA:3.40.630.10 9 334 1.0E-133 T 23-10-2018 A3L04_03165 4fbf7c619ffbbe2baa6990533bc25936 346 SUPERFAMILY SSF101821 68 177 1.24E-25 T 23-10-2018 A3L04_03165 4fbf7c619ffbbe2baa6990533bc25936 346 Gene3D G3DSA:2.40.30.40 68 161 1.0E-133 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A3L04_03165 4fbf7c619ffbbe2baa6990533bc25936 346 Pfam PF05343 M42 glutamyl aminopeptidase 45 331 7.6E-97 T 23-10-2018 IPR008007 Peptidase M42 A3L04_03165 4fbf7c619ffbbe2baa6990533bc25936 346 SUPERFAMILY SSF53187 4 341 1.64E-63 T 23-10-2018 A3L04_03165 4fbf7c619ffbbe2baa6990533bc25936 346 PIRSF PIRSF001123 1 345 2.0E-99 T 23-10-2018 IPR008007 Peptidase M42 A3L04_01445 09dc5f788bab02f2edeb9c980c953e45 349 Gene3D G3DSA:1.10.10.10 274 347 1.3E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_01445 09dc5f788bab02f2edeb9c980c953e45 349 Pfam PF01637 ATPase domain predominantly from Archaea 14 237 3.8E-21 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_01445 09dc5f788bab02f2edeb9c980c953e45 349 Gene3D G3DSA:1.10.8.60 196 273 1.5E-28 T 23-10-2018 A3L04_01445 09dc5f788bab02f2edeb9c980c953e45 349 SUPERFAMILY SSF52540 3 269 5.32E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01445 09dc5f788bab02f2edeb9c980c953e45 349 Gene3D G3DSA:3.40.50.300 1 195 3.1E-40 T 23-10-2018 A3L04_01445 09dc5f788bab02f2edeb9c980c953e45 349 SUPERFAMILY SSF46785 272 345 4.9E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_01820 f061d2af01a8cddad6f156973ffbc640 305 Pfam PF01112 Asparaginase 3 297 2.7E-96 T 23-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 A3L04_01820 f061d2af01a8cddad6f156973ffbc640 305 Gene3D G3DSA:3.60.20.30 175 302 7.5E-35 T 23-10-2018 A3L04_01820 f061d2af01a8cddad6f156973ffbc640 305 SUPERFAMILY SSF56235 19 298 1.03E-90 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L04_01120 6aa54b95fee5196242bd44a5c6d5f0d7 446 Gene3D G3DSA:3.30.460.10 13 149 1.6E-85 T 23-10-2018 A3L04_01120 6aa54b95fee5196242bd44a5c6d5f0d7 446 Pfam PF01909 Nucleotidyltransferase domain 37 138 3.1E-11 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L04_01120 6aa54b95fee5196242bd44a5c6d5f0d7 446 PIRSF PIRSF005335 1 446 1.9E-147 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 A3L04_01120 6aa54b95fee5196242bd44a5c6d5f0d7 446 SUPERFAMILY SSF55003 262 443 6.67E-39 T 23-10-2018 IPR011068 Nucleotidyltransferase, class I-like, C-terminal GO:0003723|GO:0016779|GO:0031123 A3L04_01120 6aa54b95fee5196242bd44a5c6d5f0d7 446 Gene3D G3DSA:3.30.70.1550 352 391 3.1E-18 T 23-10-2018 A3L04_01120 6aa54b95fee5196242bd44a5c6d5f0d7 446 SUPERFAMILY SSF81301 2 147 1.19E-32 T 23-10-2018 A3L04_01120 6aa54b95fee5196242bd44a5c6d5f0d7 446 TIGRFAM TIGR03671 cca_archaeal: CCA-adding enzyme 4 410 2.9E-135 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 A3L04_01120 6aa54b95fee5196242bd44a5c6d5f0d7 446 Gene3D G3DSA:1.10.1410.30 6 275 1.6E-85 T 23-10-2018 A3L04_01120 6aa54b95fee5196242bd44a5c6d5f0d7 446 Hamap MF_01264 CCA-adding enzyme [cca]. 1 446 154.632 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 A3L04_01120 6aa54b95fee5196242bd44a5c6d5f0d7 446 Gene3D G3DSA:3.30.70.590 285 421 3.1E-18 T 23-10-2018 A3L04_01120 6aa54b95fee5196242bd44a5c6d5f0d7 446 SUPERFAMILY SSF81631 150 276 1.96E-37 T 23-10-2018 A3L04_01120 6aa54b95fee5196242bd44a5c6d5f0d7 446 Pfam PF09249 tRNA nucleotidyltransferase, second domain 152 275 5.9E-39 T 23-10-2018 IPR015329 tRNA nucleotidyltransferase, substrate binding GO:0004810|GO:0016437 A3L04_08385 6c612deb9661af710f94d7ff0535dde1 71 Pfam PF01850 PIN domain 12 63 7.4E-10 T 23-10-2018 IPR002716 PIN domain A3L04_08385 6c612deb9661af710f94d7ff0535dde1 71 Gene3D G3DSA:3.40.50.1010 1 69 1.5E-6 T 23-10-2018 A3L04_08385 6c612deb9661af710f94d7ff0535dde1 71 SUPERFAMILY SSF88723 8 61 2.8E-8 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_03045 80fb288b0d1bbb0b7e8ab663124ca88a 293 Gene3D G3DSA:3.40.1190.20 2 286 8.0E-65 T 23-10-2018 IPR029056 Ribokinase-like A3L04_03045 80fb288b0d1bbb0b7e8ab663124ca88a 293 Pfam PF00294 pfkB family carbohydrate kinase 4 273 5.0E-45 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A3L04_03045 80fb288b0d1bbb0b7e8ab663124ca88a 293 SUPERFAMILY SSF53613 1 283 1.71E-65 T 23-10-2018 IPR029056 Ribokinase-like A3L04_03045 80fb288b0d1bbb0b7e8ab663124ca88a 293 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 228 241 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A3L04_03045 80fb288b0d1bbb0b7e8ab663124ca88a 293 PRINTS PR00990 Ribokinase signature 7 28 4.3E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L04_03045 80fb288b0d1bbb0b7e8ab663124ca88a 293 PRINTS PR00990 Ribokinase signature 165 180 4.3E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L04_03045 80fb288b0d1bbb0b7e8ab663124ca88a 293 PRINTS PR00990 Ribokinase signature 104 117 4.3E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L04_03045 80fb288b0d1bbb0b7e8ab663124ca88a 293 PRINTS PR00990 Ribokinase signature 198 209 4.3E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L04_03045 80fb288b0d1bbb0b7e8ab663124ca88a 293 PRINTS PR00990 Ribokinase signature 34 53 4.3E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L04_04825 038d56a29d264a5f7f93091cf05cc698 147 Gene3D G3DSA:2.40.50.140 28 147 1.9E-50 T 23-10-2018 A3L04_04825 038d56a29d264a5f7f93091cf05cc698 147 Pfam PF00164 Ribosomal protein S12/S23 32 146 1.4E-49 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_04825 038d56a29d264a5f7f93091cf05cc698 147 Hamap MF_00403_A 30S ribosomal protein S12 [rpsL]. 1 147 45.089 T 23-10-2018 IPR022863 Ribosomal protein S12, archaea A3L04_04825 038d56a29d264a5f7f93091cf05cc698 147 SUPERFAMILY SSF50249 23 147 1.03E-36 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_04825 038d56a29d264a5f7f93091cf05cc698 147 TIGRFAM TIGR00982 uS12_E_A: ribosomal protein uS12 9 147 4.3E-82 T 23-10-2018 IPR005680 Ribosomal protein S23, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_04825 038d56a29d264a5f7f93091cf05cc698 147 PIRSF PIRSF002133 19 147 9.8E-37 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_01690 a4286e7de3262bc1ae6b6b2797a4d4d7 540 Gene3D G3DSA:3.40.190.10 53 517 1.5E-51 T 23-10-2018 A3L04_01690 a4286e7de3262bc1ae6b6b2797a4d4d7 540 Pfam PF01547 Bacterial extracellular solute-binding protein 90 373 6.3E-22 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein A3L04_01690 a4286e7de3262bc1ae6b6b2797a4d4d7 540 SUPERFAMILY SSF53850 85 517 6.11E-49 T 23-10-2018 A3L04_00665 8e2b8cb1cd840fd4ee165474e54e681f 299 Gene3D G3DSA:3.40.50.150 4 291 1.3E-74 T 23-10-2018 A3L04_00665 8e2b8cb1cd840fd4ee165474e54e681f 299 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 110 124 1.2E-16 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A3L04_00665 8e2b8cb1cd840fd4ee165474e54e681f 299 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 2 18 1.2E-16 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A3L04_00665 8e2b8cb1cd840fd4ee165474e54e681f 299 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 151 164 1.2E-16 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A3L04_00665 8e2b8cb1cd840fd4ee165474e54e681f 299 Pfam PF00145 C-5 cytosine-specific DNA methylase 1 165 9.0E-45 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A3L04_00665 8e2b8cb1cd840fd4ee165474e54e681f 299 Pfam PF00145 C-5 cytosine-specific DNA methylase 229 293 6.1E-13 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A3L04_00665 8e2b8cb1cd840fd4ee165474e54e681f 299 Gene3D G3DSA:3.90.120.10 146 284 1.3E-74 T 23-10-2018 A3L04_00665 8e2b8cb1cd840fd4ee165474e54e681f 299 SUPERFAMILY SSF53335 1 295 3.94E-80 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_00665 8e2b8cb1cd840fd4ee165474e54e681f 299 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 3 164 6.9E-42 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A3L04_06275 81249864348f7b00d7681aa485bce711 382 TIGRFAM TIGR03812 tyr_de_CO2_Arch: tyrosine decarboxylase MnfA 10 381 1.2E-172 T 23-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A3L04_06275 81249864348f7b00d7681aa485bce711 382 Hamap MF_01610 Probable L-tyrosine/L-aspartate decarboxylase [mfnA]. 15 382 52.836 T 23-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A3L04_06275 81249864348f7b00d7681aa485bce711 382 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 225 246 - T 23-10-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 A3L04_06275 81249864348f7b00d7681aa485bce711 382 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 9 335 4.5E-36 T 23-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 A3L04_06275 81249864348f7b00d7681aa485bce711 382 Gene3D G3DSA:3.90.1150.10 6 375 5.6E-131 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L04_06275 81249864348f7b00d7681aa485bce711 382 Gene3D G3DSA:3.40.640.10 41 291 5.6E-131 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L04_06275 81249864348f7b00d7681aa485bce711 382 SUPERFAMILY SSF53383 2 382 1.2E-109 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L04_02870 a0daabea06873b652663745946f877f6 163 Pfam PF03975 CheD chemotactic sensory transduction 48 152 3.3E-33 T 23-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 A3L04_02870 a0daabea06873b652663745946f877f6 163 SUPERFAMILY SSF64438 4 156 6.59E-48 T 23-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic A3L04_02870 a0daabea06873b652663745946f877f6 163 Gene3D G3DSA:3.30.1330.200 2 162 2.1E-52 T 23-10-2018 IPR038592 CheD-like superfamily A3L04_02870 a0daabea06873b652663745946f877f6 163 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 1 156 28.416 T 23-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 A3L04_05495 4ebe15cd4df9aa06dc79d19386cbba4b 1067 Pfam PF08264 Anticodon-binding domain of tRNA 711 862 2.7E-37 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A3L04_05495 4ebe15cd4df9aa06dc79d19386cbba4b 1067 SUPERFAMILY SSF47323 676 906 1.48E-59 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_05495 4ebe15cd4df9aa06dc79d19386cbba4b 1067 SUPERFAMILY SSF50677 203 401 1.47E-55 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L04_05495 4ebe15cd4df9aa06dc79d19386cbba4b 1067 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 42 53 1.3E-29 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L04_05495 4ebe15cd4df9aa06dc79d19386cbba4b 1067 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 223 246 1.3E-29 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L04_05495 4ebe15cd4df9aa06dc79d19386cbba4b 1067 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 584 593 1.3E-29 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L04_05495 4ebe15cd4df9aa06dc79d19386cbba4b 1067 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 545 558 1.3E-29 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L04_05495 4ebe15cd4df9aa06dc79d19386cbba4b 1067 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 399 414 1.3E-29 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L04_05495 4ebe15cd4df9aa06dc79d19386cbba4b 1067 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 19 664 5.2E-188 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_05495 4ebe15cd4df9aa06dc79d19386cbba4b 1067 SUPERFAMILY SSF52374 2 674 2.58E-139 T 23-10-2018 A3L04_05495 4ebe15cd4df9aa06dc79d19386cbba4b 1067 Gene3D G3DSA:3.40.50.620 16 651 7.3E-232 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_05495 4ebe15cd4df9aa06dc79d19386cbba4b 1067 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_05495 4ebe15cd4df9aa06dc79d19386cbba4b 1067 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 5 1066 13.857 T 23-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L04_05495 4ebe15cd4df9aa06dc79d19386cbba4b 1067 Gene3D G3DSA:1.10.730.10 669 853 3.3E-55 T 23-10-2018 A3L04_05495 4ebe15cd4df9aa06dc79d19386cbba4b 1067 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 9 875 0.0 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L04_05495 4ebe15cd4df9aa06dc79d19386cbba4b 1067 SUPERFAMILY SSF47323 983 1051 1.9E-6 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_05495 4ebe15cd4df9aa06dc79d19386cbba4b 1067 Gene3D G3DSA:3.90.740.10 199 405 7.3E-232 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L04_06710 5f40f10102376b3bee711d3fcc9eb9d4 337 Gene3D G3DSA:3.20.20.70 119 334 5.2E-22 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_06710 5f40f10102376b3bee711d3fcc9eb9d4 337 SUPERFAMILY SSF102114 126 324 7.55E-22 T 23-10-2018 A3L04_06710 5f40f10102376b3bee711d3fcc9eb9d4 337 Pfam PF04055 Radical SAM superfamily 124 269 1.6E-17 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_06710 5f40f10102376b3bee711d3fcc9eb9d4 337 PIRSF PIRSF004869 45 337 6.4E-74 T 23-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted A3L04_06710 5f40f10102376b3bee711d3fcc9eb9d4 337 Pfam PF13353 4Fe-4S single cluster domain 122 210 6.6E-10 T 23-10-2018 A3L04_02945 effe94e171d8c3101ddb4b6239ff136a 324 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 300 3.4E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L04_02945 effe94e171d8c3101ddb4b6239ff136a 324 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 320 2.6E-21 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L04_02945 effe94e171d8c3101ddb4b6239ff136a 324 SMART SM00382 39 234 3.2E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_02945 effe94e171d8c3101ddb4b6239ff136a 324 Gene3D G3DSA:3.40.50.300 5 324 6.7E-89 T 23-10-2018 A3L04_02945 effe94e171d8c3101ddb4b6239ff136a 324 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_02945 effe94e171d8c3101ddb4b6239ff136a 324 Pfam PF00005 ABC transporter 31 184 4.1E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_02945 effe94e171d8c3101ddb4b6239ff136a 324 SUPERFAMILY SSF52540 7 256 1.36E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_07595 b278bf6440baa153daf20a8aa2d83e9d 117 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 114 3.0E-27 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A3L04_09520 ef88d7e022b53c3630ea9ba483b8ee8a 891 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_09520 ef88d7e022b53c3630ea9ba483b8ee8a 891 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 1.2E-19 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L04_09520 ef88d7e022b53c3630ea9ba483b8ee8a 891 PRINTS PR00986 Valyl-tRNA synthetase signature 450 471 1.2E-19 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L04_09520 ef88d7e022b53c3630ea9ba483b8ee8a 891 PRINTS PR00986 Valyl-tRNA synthetase signature 343 356 1.2E-19 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L04_09520 ef88d7e022b53c3630ea9ba483b8ee8a 891 PRINTS PR00986 Valyl-tRNA synthetase signature 225 242 1.2E-19 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L04_09520 ef88d7e022b53c3630ea9ba483b8ee8a 891 PRINTS PR00986 Valyl-tRNA synthetase signature 488 506 1.2E-19 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L04_09520 ef88d7e022b53c3630ea9ba483b8ee8a 891 SUPERFAMILY SSF50677 187 335 1.44E-52 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L04_09520 ef88d7e022b53c3630ea9ba483b8ee8a 891 TIGRFAM TIGR00422 valS: valine--tRNA ligase 3 857 1.5E-271 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L04_09520 ef88d7e022b53c3630ea9ba483b8ee8a 891 Gene3D G3DSA:1.10.730.10 2 753 5.4E-245 T 23-10-2018 A3L04_09520 ef88d7e022b53c3630ea9ba483b8ee8a 891 Pfam PF08264 Anticodon-binding domain of tRNA 617 765 3.3E-39 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A3L04_09520 ef88d7e022b53c3630ea9ba483b8ee8a 891 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 572 2.7E-143 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_09520 ef88d7e022b53c3630ea9ba483b8ee8a 891 Gene3D G3DSA:3.90.740.10 170 337 5.4E-245 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L04_09520 ef88d7e022b53c3630ea9ba483b8ee8a 891 SUPERFAMILY SSF52374 3 580 2.07E-129 T 23-10-2018 A3L04_09520 ef88d7e022b53c3630ea9ba483b8ee8a 891 SUPERFAMILY SSF47323 588 827 2.06E-58 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_09520 ef88d7e022b53c3630ea9ba483b8ee8a 891 Hamap MF_02005 Valine--tRNA ligase [valS]. 2 796 29.561 T 23-10-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 A3L04_09520 ef88d7e022b53c3630ea9ba483b8ee8a 891 Gene3D G3DSA:3.40.50.620 22 537 5.4E-245 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_09420 27f573fcc825c05215be767d73420c0e 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 8.8E-25 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L04_09420 27f573fcc825c05215be767d73420c0e 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 51 70 8.8E-25 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L04_09420 27f573fcc825c05215be767d73420c0e 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 293 8.8E-25 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L04_09420 27f573fcc825c05215be767d73420c0e 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 8.8E-25 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L04_09420 27f573fcc825c05215be767d73420c0e 308 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 5 307 39.869 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L04_09420 27f573fcc825c05215be767d73420c0e 308 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 6 147 2.3E-51 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A3L04_09420 27f573fcc825c05215be767d73420c0e 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 41 63 8.5E-40 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L04_09420 27f573fcc825c05215be767d73420c0e 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 225 234 8.5E-40 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L04_09420 27f573fcc825c05215be767d73420c0e 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 286 300 8.5E-40 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L04_09420 27f573fcc825c05215be767d73420c0e 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 8.5E-40 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L04_09420 27f573fcc825c05215be767d73420c0e 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 8.5E-40 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L04_09420 27f573fcc825c05215be767d73420c0e 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 80 89 8.5E-40 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L04_09420 27f573fcc825c05215be767d73420c0e 308 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 6 305 2.0E-136 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L04_09420 27f573fcc825c05215be767d73420c0e 308 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 51 58 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L04_09420 27f573fcc825c05215be767d73420c0e 308 SUPERFAMILY SSF53671 2 306 1.57E-104 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L04_09420 27f573fcc825c05215be767d73420c0e 308 Gene3D G3DSA:3.40.50.1370 7 301 3.4E-129 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L04_09420 27f573fcc825c05215be767d73420c0e 308 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 302 3.2E-32 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A3L04_09420 27f573fcc825c05215be767d73420c0e 308 Gene3D G3DSA:3.40.50.1370 135 292 3.4E-129 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L04_06250 55474cc0ae2ebb2ccceb70ed56190de6 492 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 131 150 1.2E-6 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_06250 55474cc0ae2ebb2ccceb70ed56190de6 492 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 225 249 1.2E-6 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_06250 55474cc0ae2ebb2ccceb70ed56190de6 492 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 161 185 1.2E-6 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_06250 55474cc0ae2ebb2ccceb70ed56190de6 492 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 302 321 1.2E-6 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_06250 55474cc0ae2ebb2ccceb70ed56190de6 492 Pfam PF00361 Proton-conducting membrane transporter 125 372 5.1E-40 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_02365 802dd32500010e1c99247e10c707520a 176 Pfam PF04019 Protein of unknown function (DUF359) 49 170 4.0E-37 T 23-10-2018 IPR007164 Protein of unknown function DUF359 A3L04_02365 802dd32500010e1c99247e10c707520a 176 Hamap MF_00590 UPF0218 protein . 7 172 29.683 T 23-10-2018 IPR007164 Protein of unknown function DUF359 A3L04_02365 802dd32500010e1c99247e10c707520a 176 PIRSF PIRSF006533 1 174 1.7E-54 T 23-10-2018 IPR007164 Protein of unknown function DUF359 A3L04_04835 a72b58e553575d360e4eff57072b596c 118 TIGRFAM TIGR00283 arch_pth2: peptidyl-tRNA hydrolase 5 118 2.2E-44 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 A3L04_04835 a72b58e553575d360e4eff57072b596c 118 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 4 118 1.2E-44 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 A3L04_04835 a72b58e553575d360e4eff57072b596c 118 SUPERFAMILY SSF102462 3 118 1.01E-43 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 A3L04_04835 a72b58e553575d360e4eff57072b596c 118 Gene3D G3DSA:3.40.1490.10 1 118 3.8E-49 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 A3L04_04835 a72b58e553575d360e4eff57072b596c 118 Hamap MF_00628 Peptidyl-tRNA hydrolase [pth]. 4 118 30.853 T 23-10-2018 IPR034759 Peptidyl-tRNA hydrolase, archaea GO:0004045 MetaCyc: PWY-6308 A3L04_02565 f7d6b7ef6e313b52978f994e7e53e328 358 Gene3D G3DSA:3.60.20.10 48 358 1.8E-51 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L04_02565 f7d6b7ef6e313b52978f994e7e53e328 358 Pfam PF00310 Glutamine amidotransferases class-II 99 329 5.6E-15 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A3L04_02565 f7d6b7ef6e313b52978f994e7e53e328 358 PIRSF PIRSF018774 1 358 1.1E-190 T 23-10-2018 IPR012375 Glutamate synthase large subunit domain 1 stand-alone protein A3L04_02565 f7d6b7ef6e313b52978f994e7e53e328 358 SUPERFAMILY SSF56235 12 357 1.16E-84 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L04_03950 b4a48429e99a07c6019e45d6e32c697c 228 SUPERFAMILY SSF51366 4 224 1.49E-60 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L04_03950 b4a48429e99a07c6019e45d6e32c697c 228 Gene3D G3DSA:3.20.20.70 3 228 6.9E-71 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_03950 b4a48429e99a07c6019e45d6e32c697c 228 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 1 221 31.326 T 23-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 A3L04_03950 b4a48429e99a07c6019e45d6e32c697c 228 Pfam PF00218 Indole-3-glycerol phosphate synthase 8 221 3.6E-57 T 23-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 A3L04_03950 b4a48429e99a07c6019e45d6e32c697c 228 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 18 33 - T 23-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 A3L04_06540 8255ca78db197eadfb17eb92b5b2a14c 350 SUPERFAMILY SSF53187 8 343 1.0E-42 T 23-10-2018 A3L04_06540 8255ca78db197eadfb17eb92b5b2a14c 350 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 87 124 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A3L04_06540 8255ca78db197eadfb17eb92b5b2a14c 350 Pfam PF07687 Peptidase dimerisation domain 152 257 9.9E-10 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A3L04_06540 8255ca78db197eadfb17eb92b5b2a14c 350 Pfam PF01546 Peptidase family M20/M25/M40 62 342 2.7E-25 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A3L04_06540 8255ca78db197eadfb17eb92b5b2a14c 350 Gene3D G3DSA:3.40.630.10 14 336 9.7E-64 T 23-10-2018 A3L04_06540 8255ca78db197eadfb17eb92b5b2a14c 350 Gene3D G3DSA:3.30.70.360 155 264 9.7E-64 T 23-10-2018 A3L04_06540 8255ca78db197eadfb17eb92b5b2a14c 350 SUPERFAMILY SSF55031 156 261 4.93E-11 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A3L04_07935 f7747251c74e79d17df5ec0aadfa433b 218 SMART SM00525 193 213 2.2E-5 T 23-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A3L04_07935 f7747251c74e79d17df5ec0aadfa433b 218 Hamap MF_00942 Endonuclease III [nth]. 1 216 35.778 T 23-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 A3L04_07935 f7747251c74e79d17df5ec0aadfa433b 218 SMART SM00478 42 192 1.8E-64 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A3L04_07935 f7747251c74e79d17df5ec0aadfa433b 218 Gene3D G3DSA:1.10.1670.10 19 210 4.8E-67 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A3L04_07935 f7747251c74e79d17df5ec0aadfa433b 218 Gene3D G3DSA:1.10.340.30 27 138 4.8E-67 T 23-10-2018 A3L04_07935 f7747251c74e79d17df5ec0aadfa433b 218 Pfam PF00633 Helix-hairpin-helix motif 105 134 1.4E-6 T 23-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 A3L04_07935 f7747251c74e79d17df5ec0aadfa433b 218 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 38 175 1.2E-20 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A3L04_07935 f7747251c74e79d17df5ec0aadfa433b 218 SUPERFAMILY SSF48150 11 211 3.45E-64 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A3L04_07935 f7747251c74e79d17df5ec0aadfa433b 218 ProSitePatterns PS01155 Endonuclease III family signature. 108 137 - T 23-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 A3L04_07935 f7747251c74e79d17df5ec0aadfa433b 218 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 194 210 - T 23-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A3L04_07935 f7747251c74e79d17df5ec0aadfa433b 218 PIRSF PIRSF001435 5 217 2.1E-46 T 23-10-2018 A3L04_02725 27352f51f4bf085fbd59299d2122b997 138 Gene3D G3DSA:3.40.50.1010 1 132 2.5E-29 T 23-10-2018 A3L04_02725 27352f51f4bf085fbd59299d2122b997 138 Pfam PF01850 PIN domain 2 127 2.3E-13 T 23-10-2018 IPR002716 PIN domain A3L04_02725 27352f51f4bf085fbd59299d2122b997 138 SUPERFAMILY SSF88723 2 136 2.75E-20 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_05040 9c4a080269caa1701ba137046e4a82a9 268 Gene3D G3DSA:3.30.479.30 51 182 1.0E-51 T 23-10-2018 A3L04_05040 9c4a080269caa1701ba137046e4a82a9 268 ProSitePatterns PS01270 Band 7 protein family signature. 136 164 - T 23-10-2018 IPR018080 Band 7/stomatin-like, conserved site A3L04_05040 9c4a080269caa1701ba137046e4a82a9 268 PRINTS PR00721 Stomatin signature 30 52 1.8E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L04_05040 9c4a080269caa1701ba137046e4a82a9 268 PRINTS PR00721 Stomatin signature 112 129 1.8E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L04_05040 9c4a080269caa1701ba137046e4a82a9 268 PRINTS PR00721 Stomatin signature 77 98 1.8E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L04_05040 9c4a080269caa1701ba137046e4a82a9 268 PRINTS PR00721 Stomatin signature 132 155 1.8E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L04_05040 9c4a080269caa1701ba137046e4a82a9 268 PRINTS PR00721 Stomatin signature 200 223 1.8E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L04_05040 9c4a080269caa1701ba137046e4a82a9 268 PRINTS PR00721 Stomatin signature 175 196 1.8E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L04_05040 9c4a080269caa1701ba137046e4a82a9 268 PRINTS PR00721 Stomatin signature 156 174 1.8E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L04_05040 9c4a080269caa1701ba137046e4a82a9 268 SMART SM00244 23 180 3.8E-72 T 23-10-2018 IPR001107 Band 7 domain A3L04_05040 9c4a080269caa1701ba137046e4a82a9 268 SUPERFAMILY SSF117892 54 187 4.45E-47 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily A3L04_05040 9c4a080269caa1701ba137046e4a82a9 268 Pfam PF01145 SPFH domain / Band 7 family 27 197 1.1E-38 T 23-10-2018 IPR001107 Band 7 domain A3L04_07580 b8e264413157482dffd2b7c488f2a606 173 SUPERFAMILY SSF56770 30 160 3.66E-53 T 23-10-2018 A3L04_07580 b8e264413157482dffd2b7c488f2a606 173 Gene3D G3DSA:3.40.50.12280 9 173 1.6E-52 T 23-10-2018 A3L04_07580 b8e264413157482dffd2b7c488f2a606 173 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 43 152 1.0E-27 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_00975 c71ce7de3754edead0d4bc811f48dddf 344 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_00975 c71ce7de3754edead0d4bc811f48dddf 344 Pfam PF03459 TOBE domain 281 343 2.5E-16 T 23-10-2018 IPR005116 Transport-associated OB, type 1 A3L04_00975 c71ce7de3754edead0d4bc811f48dddf 344 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 280 343 8.9E-22 T 23-10-2018 IPR004606 Molybdenum-pterin binding GO:0015689 A3L04_00975 c71ce7de3754edead0d4bc811f48dddf 344 Gene3D G3DSA:2.40.50.100 268 339 2.5E-30 T 23-10-2018 A3L04_00975 c71ce7de3754edead0d4bc811f48dddf 344 SUPERFAMILY SSF50331 235 344 1.05E-23 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L04_00975 c71ce7de3754edead0d4bc811f48dddf 344 SUPERFAMILY SSF52540 1 237 1.86E-79 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_00975 c71ce7de3754edead0d4bc811f48dddf 344 SMART SM00382 25 330 1.1E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_00975 c71ce7de3754edead0d4bc811f48dddf 344 Gene3D G3DSA:3.40.50.300 1 234 6.9E-73 T 23-10-2018 A3L04_00975 c71ce7de3754edead0d4bc811f48dddf 344 Pfam PF00005 ABC transporter 16 159 1.8E-34 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_00975 c71ce7de3754edead0d4bc811f48dddf 344 Gene3D G3DSA:2.40.50.140 242 343 2.5E-30 T 23-10-2018 A3L04_05420 224dabd9d47788e37eebd0295de6249b 873 Pfam PF00271 Helicase conserved C-terminal domain 268 372 2.8E-18 T 23-10-2018 IPR001650 Helicase, C-terminal A3L04_05420 224dabd9d47788e37eebd0295de6249b 873 Gene3D G3DSA:3.40.50.300 251 401 1.2E-24 T 23-10-2018 A3L04_05420 224dabd9d47788e37eebd0295de6249b 873 SMART SM00487 42 252 1.4E-30 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L04_05420 224dabd9d47788e37eebd0295de6249b 873 Pfam PF00270 DEAD/DEAH box helicase 48 222 8.2E-23 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L04_05420 224dabd9d47788e37eebd0295de6249b 873 SUPERFAMILY SSF52540 92 382 7.56E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_05420 224dabd9d47788e37eebd0295de6249b 873 SMART SM00490 291 374 2.5E-18 T 23-10-2018 IPR001650 Helicase, C-terminal A3L04_05420 224dabd9d47788e37eebd0295de6249b 873 Gene3D G3DSA:3.40.50.300 29 240 1.0E-40 T 23-10-2018 A3L04_05420 224dabd9d47788e37eebd0295de6249b 873 Pfam PF09369 Domain of unknown function (DUF1998) 767 844 6.3E-14 T 23-10-2018 IPR018973 DEAD/DEAH-box helicase, putative A3L04_10260 bd1995ccfb0e1937072ea1372b963519 530 Gene3D G3DSA:3.10.620.30 255 401 6.5E-8 T 23-10-2018 A3L04_10260 bd1995ccfb0e1937072ea1372b963519 530 SUPERFAMILY SSF54001 258 437 9.16E-11 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A3L04_10260 bd1995ccfb0e1937072ea1372b963519 530 SUPERFAMILY SSF49384 26 156 2.2E-5 T 23-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 A3L04_00270 19f3ab85bf0b7e004a2c4bf08555952b 83 Gene3D G3DSA:2.20.25.30 9 83 4.3E-31 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_00270 19f3ab85bf0b7e004a2c4bf08555952b 83 TIGRFAM TIGR00280 eL43_euk_arch: ribosomal protein eL43 1 80 1.2E-37 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_00270 19f3ab85bf0b7e004a2c4bf08555952b 83 Pfam PF01780 Ribosomal L37ae protein family 4 81 1.7E-33 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_00270 19f3ab85bf0b7e004a2c4bf08555952b 83 SUPERFAMILY SSF57829 10 80 1.22E-28 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L04_00270 19f3ab85bf0b7e004a2c4bf08555952b 83 Hamap MF_00327 50S ribosomal protein L37Ae [rpl37ae]. 3 71 25.232 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_03485 e33fe0ab83538145d65a184dfb953e2d 155 Hamap MF_01371_A 50S ribosomal protein L30 [rpmD]. 1 155 86.549 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 A3L04_03485 e33fe0ab83538145d65a184dfb953e2d 155 SUPERFAMILY SSF55129 4 155 2.09E-52 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily A3L04_03485 e33fe0ab83538145d65a184dfb953e2d 155 Gene3D G3DSA:1.10.15.30 60 114 7.0E-60 T 23-10-2018 IPR023106 Ribosomal protein L30, central domain, archaeal type A3L04_03485 e33fe0ab83538145d65a184dfb953e2d 155 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 4.2E-17 T 23-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A3L04_03485 e33fe0ab83538145d65a184dfb953e2d 155 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 23-10-2018 IPR018038 Ribosomal protein L30, conserved site A3L04_03485 e33fe0ab83538145d65a184dfb953e2d 155 Gene3D G3DSA:3.30.1390.20 5 143 7.0E-60 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily A3L04_03485 e33fe0ab83538145d65a184dfb953e2d 155 TIGRFAM TIGR01309 uL30_arch: ribosomal protein uL30 4 155 1.4E-67 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 A3L04_09640 72361bca356cc03fc8ae2ed2fd567e74 333 SUPERFAMILY SSF51161 204 315 1.91E-13 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A3L04_09640 72361bca356cc03fc8ae2ed2fd567e74 333 Pfam PF00483 Nucleotidyl transferase 2 232 5.5E-43 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L04_09640 72361bca356cc03fc8ae2ed2fd567e74 333 Gene3D G3DSA:2.160.10.10 236 332 1.1E-8 T 23-10-2018 A3L04_09640 72361bca356cc03fc8ae2ed2fd567e74 333 SUPERFAMILY SSF53448 2 238 2.82E-55 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_09640 72361bca356cc03fc8ae2ed2fd567e74 333 Gene3D G3DSA:3.90.550.10 1 235 4.8E-54 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_07705 880c2fbd0864603a37f84f07e59f33a7 441 Gene3D G3DSA:3.40.50.1100 47 357 1.6E-98 T 23-10-2018 A3L04_07705 880c2fbd0864603a37f84f07e59f33a7 441 SMART SM00418 363 441 2.3E-11 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_07705 880c2fbd0864603a37f84f07e59f33a7 441 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 60 352 8.0E-65 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L04_07705 880c2fbd0864603a37f84f07e59f33a7 441 SUPERFAMILY SSF53686 2 369 8.25E-80 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L04_07705 880c2fbd0864603a37f84f07e59f33a7 441 SUPERFAMILY SSF46785 370 438 6.48E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_07705 880c2fbd0864603a37f84f07e59f33a7 441 Gene3D G3DSA:1.10.10.10 368 440 5.6E-13 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_07705 880c2fbd0864603a37f84f07e59f33a7 441 Gene3D G3DSA:3.40.50.1100 94 190 1.6E-98 T 23-10-2018 A3L04_07960 59dbec632964bc3459e56c7ce338817d 952 Gene3D G3DSA:3.20.20.80 645 951 7.8E-104 T 23-10-2018 A3L04_07960 59dbec632964bc3459e56c7ce338817d 952 SUPERFAMILY SSF49899 51 282 2.94E-41 T 23-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A3L04_07960 59dbec632964bc3459e56c7ce338817d 952 SUPERFAMILY SSF49384 327 409 6.35E-12 T 23-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 A3L04_07960 59dbec632964bc3459e56c7ce338817d 952 Pfam PF00553 Cellulose binding domain 329 412 2.0E-5 T 23-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A3L04_07960 59dbec632964bc3459e56c7ce338817d 952 Pfam PF00553 Cellulose binding domain 497 582 1.6E-6 T 23-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A3L04_07960 59dbec632964bc3459e56c7ce338817d 952 Gene3D G3DSA:2.60.40.290 316 417 2.9E-34 T 23-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 A3L04_07960 59dbec632964bc3459e56c7ce338817d 952 Gene3D G3DSA:2.60.40.290 486 587 2.8E-37 T 23-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 A3L04_07960 59dbec632964bc3459e56c7ce338817d 952 SUPERFAMILY SSF49384 491 583 1.19E-12 T 23-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 A3L04_07960 59dbec632964bc3459e56c7ce338817d 952 Gene3D G3DSA:2.60.120.180 28 293 1.3E-74 T 23-10-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A3L04_07960 59dbec632964bc3459e56c7ce338817d 952 SUPERFAMILY SSF51445 650 912 7.03E-23 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L04_07960 59dbec632964bc3459e56c7ce338817d 952 Pfam PF01670 Glycosyl hydrolase family 12 52 284 4.0E-37 T 23-10-2018 IPR002594 Glycoside hydrolase family 12 GO:0000272|GO:0008810 A3L04_07960 59dbec632964bc3459e56c7ce338817d 952 SMART SM00637 322 407 3.3E-11 T 23-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A3L04_07960 59dbec632964bc3459e56c7ce338817d 952 SMART SM00637 492 574 5.6E-12 T 23-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A3L04_02835 14ab7b84388cf6e3d22221848b9c20ab 383 SMART SM00283 104 365 7.8E-51 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A3L04_02835 14ab7b84388cf6e3d22221848b9c20ab 383 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 152 331 1.4E-40 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A3L04_02835 14ab7b84388cf6e3d22221848b9c20ab 383 SUPERFAMILY SSF58104 110 371 6.8E-61 T 23-10-2018 A3L04_02835 14ab7b84388cf6e3d22221848b9c20ab 383 Gene3D G3DSA:1.10.287.950 71 379 1.9E-57 T 23-10-2018 A3L04_02835 14ab7b84388cf6e3d22221848b9c20ab 383 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 231 260 3.7E-23 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A3L04_02835 14ab7b84388cf6e3d22221848b9c20ab 383 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 202 229 3.7E-23 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A3L04_02835 14ab7b84388cf6e3d22221848b9c20ab 383 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 125 154 3.7E-23 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A3L04_02835 14ab7b84388cf6e3d22221848b9c20ab 383 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 279 308 3.7E-23 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A3L04_04495 5a60d77f9955efc8d5ff9f645e8e3cc0 158 TIGRFAM TIGR00286 TIGR00286: arginine decarboxylase, pyruvoyl-dependent 6 154 1.8E-40 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L04_04495 5a60d77f9955efc8d5ff9f645e8e3cc0 158 PIRSF PIRSF005216 2 158 1.6E-49 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L04_04495 5a60d77f9955efc8d5ff9f645e8e3cc0 158 Pfam PF01862 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) 5 155 6.9E-43 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L04_04495 5a60d77f9955efc8d5ff9f645e8e3cc0 158 ProDom PD010449 DECARBOXYLASE PYRUVOYL-DEPENDENT ARGININE SUBUNIT ALPHA CONTAINS: BETA PVLARGDC LYA DECARBOX 6 142 1.0E-62 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L04_04495 5a60d77f9955efc8d5ff9f645e8e3cc0 158 Gene3D G3DSA:3.30.60.30 1 43 2.2E-18 T 23-10-2018 A3L04_04495 5a60d77f9955efc8d5ff9f645e8e3cc0 158 SUPERFAMILY SSF56271 2 156 6.02E-45 T 23-10-2018 IPR016104 Pyruvoyl-dependent histidine/arginine decarboxylase GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L04_04495 5a60d77f9955efc8d5ff9f645e8e3cc0 158 Hamap MF_01404 Pyruvoyl-dependent arginine decarboxylase [pdaD]. 1 158 48.031 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L04_04495 5a60d77f9955efc8d5ff9f645e8e3cc0 158 Gene3D G3DSA:3.50.20.10 44 157 3.2E-34 T 23-10-2018 IPR016105 Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L04_01375 d09de75c093f576cf2b9b5bdb9c14cbb 232 Gene3D G3DSA:3.40.109.10 25 231 5.4E-72 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L04_01375 d09de75c093f576cf2b9b5bdb9c14cbb 232 Pfam PF00881 Nitroreductase family 56 231 8.1E-34 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A3L04_01375 d09de75c093f576cf2b9b5bdb9c14cbb 232 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 71 231 3.0E-45 T 23-10-2018 IPR020051 SagB-type dehydrogenase domain A3L04_01375 d09de75c093f576cf2b9b5bdb9c14cbb 232 SUPERFAMILY SSF55469 50 231 1.93E-36 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L04_10565 55e9027764639695d0d77e1d88ee2018 159 Gene3D G3DSA:1.20.5.340 7 142 1.7E-8 T 23-10-2018 A3L04_10565 55e9027764639695d0d77e1d88ee2018 159 Pfam PF05377 Flagella accessory protein C (FlaC) 50 103 5.9E-20 T 23-10-2018 IPR009205 Predicted archaeal flagellar protein C A3L04_10565 55e9027764639695d0d77e1d88ee2018 159 PIRSF PIRSF018660 6 159 2.2E-18 T 23-10-2018 IPR009205 Predicted archaeal flagellar protein C A3L04_10565 55e9027764639695d0d77e1d88ee2018 159 SUPERFAMILY SSF57997 26 140 2.32E-6 T 23-10-2018 A3L04_04125 c8888083c3dd3586f051f32d7d5f0599 221 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 64 75 9.4E-12 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_04125 c8888083c3dd3586f051f32d7d5f0599 221 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 9.4E-12 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_04125 c8888083c3dd3586f051f32d7d5f0599 221 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 154 9.4E-12 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_04125 c8888083c3dd3586f051f32d7d5f0599 221 SUPERFAMILY SSF51735 3 202 8.0E-41 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_04125 c8888083c3dd3586f051f32d7d5f0599 221 Pfam PF00106 short chain dehydrogenase 3 172 6.8E-31 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_04125 c8888083c3dd3586f051f32d7d5f0599 221 Gene3D G3DSA:3.40.50.720 2 210 3.0E-43 T 23-10-2018 A3L04_08330 2e5e29a67a2eddaf6e685eb5c8cc1a65 79 Pfam PF01938 TRAM domain 22 78 7.4E-14 T 23-10-2018 IPR002792 TRAM domain A3L04_08330 2e5e29a67a2eddaf6e685eb5c8cc1a65 79 SUPERFAMILY SSF50249 18 79 8.18E-18 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_08330 2e5e29a67a2eddaf6e685eb5c8cc1a65 79 Gene3D G3DSA:2.40.50.140 11 78 7.0E-27 T 23-10-2018 A3L04_01640 519d1accb75f8c892d4a79bd7aa7b4bf 350 Pfam PF01896 DNA primase small subunit 94 306 1.8E-13 T 23-10-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 A3L04_01640 519d1accb75f8c892d4a79bd7aa7b4bf 350 Hamap MF_00700 DNA primase small subunit PriS [priS]. 9 349 23.492 T 23-10-2018 IPR023639 DNA primase small subunit PriS GO:0003896 A3L04_01640 519d1accb75f8c892d4a79bd7aa7b4bf 350 Gene3D G3DSA:1.10.8.160 172 279 1.6E-135 T 23-10-2018 A3L04_01640 519d1accb75f8c892d4a79bd7aa7b4bf 350 TIGRFAM TIGR00335 primase_sml: putative DNA primase, eukaryotic-type, small subunit 10 331 2.9E-53 T 23-10-2018 IPR014052 DNA primase, small subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 A3L04_01640 519d1accb75f8c892d4a79bd7aa7b4bf 350 Gene3D G3DSA:3.90.920.10 7 328 1.6E-135 T 23-10-2018 A3L04_01640 519d1accb75f8c892d4a79bd7aa7b4bf 350 SUPERFAMILY SSF56747 3 342 3.71E-95 T 23-10-2018 A3L04_09630 aa2adbdf506445356c7f003326378660 207 Pfam PF04254 Protein of unknown function (DUF432) 48 160 1.9E-26 T 23-10-2018 IPR007366 Protein of unknown function DUF432 A3L04_09630 aa2adbdf506445356c7f003326378660 207 PIRSF PIRSF019202 1 207 2.0E-63 T 23-10-2018 IPR007366 Protein of unknown function DUF432 A3L04_09925 f093996ec10a4dfce77df27b20ba91c6 314 PIRSF PIRSF002849 1 313 2.6E-140 T 23-10-2018 A3L04_09925 f093996ec10a4dfce77df27b20ba91c6 314 SUPERFAMILY SSF52540 9 284 1.85E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09925 f093996ec10a4dfce77df27b20ba91c6 314 Gene3D G3DSA:3.40.50.300 18 184 8.5E-48 T 23-10-2018 A3L04_09925 f093996ec10a4dfce77df27b20ba91c6 314 Gene3D G3DSA:1.10.8.300 199 308 8.6E-39 T 23-10-2018 A3L04_09925 f093996ec10a4dfce77df27b20ba91c6 314 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 37 167 2.0E-68 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A3L04_10600 77d3e5a5c54b3976a696747720c388ab 250 Pfam PF02985 HEAT repeat 179 206 3.1E-4 T 23-10-2018 IPR000357 HEAT repeat GO:0005515 A3L04_10600 77d3e5a5c54b3976a696747720c388ab 250 SUPERFAMILY SSF48371 27 242 4.93E-22 T 23-10-2018 IPR016024 Armadillo-type fold A3L04_10600 77d3e5a5c54b3976a696747720c388ab 250 Gene3D G3DSA:1.25.10.10 1 249 4.2E-87 T 23-10-2018 IPR011989 Armadillo-like helical A3L04_01685 b9fc2d3bc56386ae6508353804fa2bef 312 Gene3D G3DSA:1.10.3720.10 52 303 1.1E-43 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_01685 b9fc2d3bc56386ae6508353804fa2bef 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 291 1.1E-12 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L04_01685 b9fc2d3bc56386ae6508353804fa2bef 312 SUPERFAMILY SSF161098 54 290 2.22E-38 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_07980 10565415153fb30ab6e57c8ee95ff288 245 Gene3D G3DSA:3.30.390.100 16 102 6.9E-26 T 23-10-2018 A3L04_07980 10565415153fb30ab6e57c8ee95ff288 245 SUPERFAMILY SSF159713 4 241 2.75E-59 T 23-10-2018 A3L04_07980 10565415153fb30ab6e57c8ee95ff288 245 Pfam PF13938 Putative heavy-metal chelation 9 89 1.4E-14 T 23-10-2018 IPR025251 Domain of unknown function DUF4213 A3L04_07980 10565415153fb30ab6e57c8ee95ff288 245 Pfam PF04016 Putative heavy-metal chelation 110 240 4.4E-31 T 23-10-2018 IPR007161 Putative heavy-metal chelation domain A3L04_07980 10565415153fb30ab6e57c8ee95ff288 245 Gene3D G3DSA:3.40.50.11590 103 213 6.9E-26 T 23-10-2018 A3L04_00535 4cc3c16588315cac7d20017cf5dd9d7c 364 Pfam PF08402 TOBE domain 279 355 1.7E-9 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A3L04_00535 4cc3c16588315cac7d20017cf5dd9d7c 364 Gene3D G3DSA:2.40.50.140 281 348 1.6E-35 T 23-10-2018 A3L04_00535 4cc3c16588315cac7d20017cf5dd9d7c 364 Pfam PF00005 ABC transporter 20 161 5.4E-34 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_00535 4cc3c16588315cac7d20017cf5dd9d7c 364 SUPERFAMILY SSF52540 4 243 4.09E-91 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_00535 4cc3c16588315cac7d20017cf5dd9d7c 364 Gene3D G3DSA:3.40.50.300 1 238 3.2E-81 T 23-10-2018 A3L04_00535 4cc3c16588315cac7d20017cf5dd9d7c 364 SMART SM00382 28 211 1.0E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_00535 4cc3c16588315cac7d20017cf5dd9d7c 364 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_00535 4cc3c16588315cac7d20017cf5dd9d7c 364 SUPERFAMILY SSF50331 237 363 1.75E-26 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L04_01900 5bcf39c160436fc1c5b7733e95220b9c 598 Pfam PF13522 Glutamine amidotransferase domain 65 194 2.6E-22 T 23-10-2018 A3L04_01900 5bcf39c160436fc1c5b7733e95220b9c 598 Gene3D G3DSA:3.40.50.10490 251 597 1.1E-134 T 23-10-2018 A3L04_01900 5bcf39c160436fc1c5b7733e95220b9c 598 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 598 1.3E-248 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A3L04_01900 5bcf39c160436fc1c5b7733e95220b9c 598 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 598 41.011 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A3L04_01900 5bcf39c160436fc1c5b7733e95220b9c 598 SUPERFAMILY SSF53697 247 598 2.6E-104 T 23-10-2018 A3L04_01900 5bcf39c160436fc1c5b7733e95220b9c 598 Gene3D G3DSA:3.40.50.10490 438 583 1.1E-134 T 23-10-2018 A3L04_01900 5bcf39c160436fc1c5b7733e95220b9c 598 Gene3D G3DSA:3.60.20.10 2 239 3.1E-82 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L04_01900 5bcf39c160436fc1c5b7733e95220b9c 598 Pfam PF01380 SIS domain 453 580 3.1E-23 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A3L04_01900 5bcf39c160436fc1c5b7733e95220b9c 598 Pfam PF01380 SIS domain 286 410 8.3E-33 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A3L04_01900 5bcf39c160436fc1c5b7733e95220b9c 598 SUPERFAMILY SSF56235 2 227 2.74E-77 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L04_10785 18a0136262fea3ec4362a4354c4f713c 334 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A3L04_10785 18a0136262fea3ec4362a4354c4f713c 334 Gene3D G3DSA:3.40.50.720 95 285 1.2E-113 T 23-10-2018 A3L04_10785 18a0136262fea3ec4362a4354c4f713c 334 Gene3D G3DSA:3.40.50.720 16 317 1.2E-113 T 23-10-2018 A3L04_10785 18a0136262fea3ec4362a4354c4f713c 334 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 285 3.3E-55 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A3L04_10785 18a0136262fea3ec4362a4354c4f713c 334 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 10 317 2.7E-35 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A3L04_10785 18a0136262fea3ec4362a4354c4f713c 334 SUPERFAMILY SSF52283 1 132 7.37E-35 T 23-10-2018 A3L04_10785 18a0136262fea3ec4362a4354c4f713c 334 SUPERFAMILY SSF51735 98 286 1.75E-52 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_01940 13c429abebe2f8a0cbf614b1528cb1e9 231 SUPERFAMILY SSF56784 1 227 3.56E-38 T 23-10-2018 IPR036412 HAD-like superfamily A3L04_01940 13c429abebe2f8a0cbf614b1528cb1e9 231 Gene3D G3DSA:3.40.50.1000 2 215 6.9E-74 T 23-10-2018 IPR023214 HAD superfamily A3L04_01940 13c429abebe2f8a0cbf614b1528cb1e9 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 50 199 1.0E-16 T 23-10-2018 A3L04_01940 13c429abebe2f8a0cbf614b1528cb1e9 231 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 146 199 4.7E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_01940 13c429abebe2f8a0cbf614b1528cb1e9 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 135 193 1.6E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_01940 13c429abebe2f8a0cbf614b1528cb1e9 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 108 121 3.0E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_01940 13c429abebe2f8a0cbf614b1528cb1e9 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 158 3.0E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_01940 13c429abebe2f8a0cbf614b1528cb1e9 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 3.0E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_01940 13c429abebe2f8a0cbf614b1528cb1e9 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 188 201 3.0E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_01940 13c429abebe2f8a0cbf614b1528cb1e9 231 Gene3D G3DSA:1.10.150.400 14 92 6.9E-74 T 23-10-2018 A3L04_08540 fdcc05fe15882e9f73a345e1b5da253c 436 Pfam PF09376 NurA domain 58 404 1.1E-13 T 23-10-2018 IPR018977 NurA domain A3L04_08540 fdcc05fe15882e9f73a345e1b5da253c 436 SMART SM00933 57 404 1.9E-15 T 23-10-2018 IPR018977 NurA domain A3L04_08895 748579c3a30ff91437c5f35ab07de8d7 278 Gene3D G3DSA:3.40.50.150 109 275 1.6E-26 T 23-10-2018 A3L04_08895 748579c3a30ff91437c5f35ab07de8d7 278 Pfam PF13649 Methyltransferase domain 127 228 4.7E-10 T 23-10-2018 A3L04_08895 748579c3a30ff91437c5f35ab07de8d7 278 SUPERFAMILY SSF53335 87 262 4.29E-39 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_03465 6c7757597c6d98df61f1c3bdd73517b3 130 SUPERFAMILY SSF52042 4 128 1.96E-49 T 23-10-2018 IPR036351 Ribosomal protein L32e superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03465 6c7757597c6d98df61f1c3bdd73517b3 130 SMART SM01393 20 127 2.4E-65 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03465 6c7757597c6d98df61f1c3bdd73517b3 130 Hamap MF_00810 50S ribosomal protein L32e [rpl32e]. 4 128 33.37 T 23-10-2018 IPR023654 Ribosomal protein L32e, archaeal GO:0003735|GO:0005840|GO:0006412 A3L04_03465 6c7757597c6d98df61f1c3bdd73517b3 130 ProSitePatterns PS00580 Ribosomal protein L32e signature. 23 45 - T 23-10-2018 IPR018263 Ribosomal protein L32e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03465 6c7757597c6d98df61f1c3bdd73517b3 130 Pfam PF01655 Ribosomal protein L32 20 127 1.1E-43 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03465 6c7757597c6d98df61f1c3bdd73517b3 130 ProDom PD003823 RIBOSOMAL L32 RIBONUCLEOPROTEIN 60S L32E 50S L32 STRAIN CHROMOSOME DIRECT 23 128 2.0E-54 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_00660 1ffa21c3cbf7b26b83dcc0634cbfbab7 419 Gene3D G3DSA:3.40.720.10 15 405 6.0E-145 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L04_00660 1ffa21c3cbf7b26b83dcc0634cbfbab7 419 Pfam PF01676 Metalloenzyme superfamily 13 408 9.6E-56 T 23-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 A3L04_00660 1ffa21c3cbf7b26b83dcc0634cbfbab7 419 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 48 216 1.3E-54 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_00660 1ffa21c3cbf7b26b83dcc0634cbfbab7 419 Hamap MF_01402_A 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 12 410 46.251 T 23-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_00660 1ffa21c3cbf7b26b83dcc0634cbfbab7 419 PIRSF PIRSF006392 9 415 2.6E-156 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_00660 1ffa21c3cbf7b26b83dcc0634cbfbab7 419 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 15 409 5.2E-137 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L04_00660 1ffa21c3cbf7b26b83dcc0634cbfbab7 419 SUPERFAMILY SSF53649 12 412 1.6E-44 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L04_00660 1ffa21c3cbf7b26b83dcc0634cbfbab7 419 Gene3D G3DSA:3.30.70.2130 89 238 6.0E-145 T 23-10-2018 A3L04_00110 374a2b03b41deab9e53c17b78ad4b244 425 Pfam PF00919 Uncharacterized protein family UPF0004 3 88 2.8E-20 T 23-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 A3L04_00110 374a2b03b41deab9e53c17b78ad4b244 425 Pfam PF04055 Radical SAM superfamily 142 314 9.8E-24 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_00110 374a2b03b41deab9e53c17b78ad4b244 425 Pfam PF01938 TRAM domain 366 424 1.2E-7 T 23-10-2018 IPR002792 TRAM domain A3L04_00110 374a2b03b41deab9e53c17b78ad4b244 425 TIGRFAM TIGR01578 MiaB-like-B: MiaB-like tRNA modifying enzyme, archaeal-type 3 424 9.2E-145 T 23-10-2018 IPR006466 MiaB-like tRNA modifying enzyme, archaeal-type Reactome: R-HSA-6782315 A3L04_00110 374a2b03b41deab9e53c17b78ad4b244 425 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 421 2.6E-133 T 23-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 A3L04_00110 374a2b03b41deab9e53c17b78ad4b244 425 SMART SM00729 138 355 1.9E-60 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L04_00110 374a2b03b41deab9e53c17b78ad4b244 425 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 142 162 - T 23-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 A3L04_00110 374a2b03b41deab9e53c17b78ad4b244 425 Gene3D G3DSA:3.40.50.12160 2 126 6.7E-24 T 23-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily A3L04_00110 374a2b03b41deab9e53c17b78ad4b244 425 Gene3D G3DSA:3.80.30.20 138 369 7.8E-74 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L04_00110 374a2b03b41deab9e53c17b78ad4b244 425 SUPERFAMILY SSF102114 127 364 1.14E-53 T 23-10-2018 A3L04_02625 7985a36d14683f64704fd82d72e040e6 226 Gene3D G3DSA:1.10.10.10 184 226 3.3E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_02625 7985a36d14683f64704fd82d72e040e6 226 Gene3D G3DSA:3.40.50.300 4 103 4.7E-7 T 23-10-2018 A3L04_02625 7985a36d14683f64704fd82d72e040e6 226 SUPERFAMILY SSF52540 9 175 4.18E-7 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_02625 7985a36d14683f64704fd82d72e040e6 226 Gene3D G3DSA:1.10.8.60 108 183 5.2E-24 T 23-10-2018 A3L04_10765 ac192fd2cdc62f48ab6a9bd515e290be 437 Pfam PF07282 Putative transposase DNA-binding domain 322 391 5.6E-21 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L04_10765 ac192fd2cdc62f48ab6a9bd515e290be 437 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 264 348 2.8E-13 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L04_07805 4344367e8c0a159205e411f86bf3dea2 260 PIRSF PIRSF004853 1 253 7.8E-120 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase A3L04_07805 4344367e8c0a159205e411f86bf3dea2 260 ProDom PD016827 ARCHAEA ST0532 APE1937 VNG0250C MM2281 PAE3406 AF0927 UNCHARACTERIZED C3_0043 MJ0209 71 248 2.0E-84 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase A3L04_07805 4344367e8c0a159205e411f86bf3dea2 260 Gene3D G3DSA:3.40.50.12640 1 260 1.3E-120 T 23-10-2018 IPR038138 Phosphopantoate/pantothenate synthetase superfamily A3L04_07805 4344367e8c0a159205e411f86bf3dea2 260 Pfam PF02006 Phosphopantothenate/pantothenate synthetase 66 240 2.1E-79 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase A3L04_03230 39548eacb79d6855242f2f466a0609b5 252 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 221 2.2E-21 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L04_03230 39548eacb79d6855242f2f466a0609b5 252 Gene3D G3DSA:3.40.50.300 2 240 6.2E-48 T 23-10-2018 A3L04_03230 39548eacb79d6855242f2f466a0609b5 252 SUPERFAMILY SSF52540 1 237 1.99E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_05230 2eb72654804ead786e2ffd56f402094e 267 Pfam PF01261 Xylose isomerase-like TIM barrel 22 209 8.4E-26 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A3L04_05230 2eb72654804ead786e2ffd56f402094e 267 Gene3D G3DSA:3.20.20.150 1 266 1.1E-53 T 23-10-2018 A3L04_05230 2eb72654804ead786e2ffd56f402094e 267 SUPERFAMILY SSF51658 4 263 2.23E-45 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily A3L04_03850 958dc0847c93b7529cd712a5c1fab8db 272 Gene3D G3DSA:3.40.50.10860 8 257 4.1E-92 T 23-10-2018 A3L04_03850 958dc0847c93b7529cd712a5c1fab8db 272 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 7 268 8.4E-87 T 23-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A3L04_03850 958dc0847c93b7529cd712a5c1fab8db 272 SUPERFAMILY SSF53223 3 103 6.91E-32 T 23-10-2018 A3L04_03850 958dc0847c93b7529cd712a5c1fab8db 272 Gene3D G3DSA:3.40.50.720 103 234 4.1E-92 T 23-10-2018 A3L04_03850 958dc0847c93b7529cd712a5c1fab8db 272 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 5 266 35.86 T 23-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A3L04_03850 958dc0847c93b7529cd712a5c1fab8db 272 SUPERFAMILY SSF51735 104 266 7.18E-44 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_03850 958dc0847c93b7529cd712a5c1fab8db 272 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 111 189 4.4E-12 T 23-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase A3L04_03850 958dc0847c93b7529cd712a5c1fab8db 272 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 10 91 9.1E-29 T 23-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A3L04_06705 a5f7a1c2d90181970777d044d4f03cfc 369 SUPERFAMILY SSF53649 2 356 4.74E-73 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L04_06705 a5f7a1c2d90181970777d044d4f03cfc 369 Gene3D G3DSA:3.40.720.10 1 367 1.1E-52 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L04_06705 a5f7a1c2d90181970777d044d4f03cfc 369 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 4 320 2.6E-51 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A3L04_09020 16da342aae055e8fcbff6df8778278f0 322 Pfam PF01867 CRISPR associated protein Cas1 7 277 9.2E-83 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 A3L04_09020 16da342aae055e8fcbff6df8778278f0 322 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 307 24.737 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 A3L04_09020 16da342aae055e8fcbff6df8778278f0 322 Gene3D G3DSA:1.20.120.920 83 322 5.1E-66 T 23-10-2018 A3L04_09020 16da342aae055e8fcbff6df8778278f0 322 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 5 321 1.8E-133 T 23-10-2018 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype GO:0004520|GO:0043571|GO:0046872 A3L04_09020 16da342aae055e8fcbff6df8778278f0 322 Gene3D G3DSA:3.100.10.20 1 82 2.2E-29 T 23-10-2018 A3L04_09020 16da342aae055e8fcbff6df8778278f0 322 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 6 317 1.6E-96 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 A3L04_05990 816e553fcd30bd941257965fe8ae5455 556 Gene3D G3DSA:3.30.930.10 366 555 3.7E-52 T 23-10-2018 A3L04_05990 816e553fcd30bd941257965fe8ae5455 556 SUPERFAMILY SSF46955 5 81 4.39E-8 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily A3L04_05990 816e553fcd30bd941257965fe8ae5455 556 SUPERFAMILY SSF46955 280 352 2.38E-16 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily A3L04_05990 816e553fcd30bd941257965fe8ae5455 556 Gene3D G3DSA:3.30.56.10 279 348 5.8E-28 T 23-10-2018 A3L04_05990 816e553fcd30bd941257965fe8ae5455 556 Pfam PF03483 B3/4 domain 102 244 1.3E-18 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A3L04_05990 816e553fcd30bd941257965fe8ae5455 556 SMART SM00874 280 348 2.7E-18 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A3L04_05990 816e553fcd30bd941257965fe8ae5455 556 SUPERFAMILY SSF55681 345 553 6.83E-49 T 23-10-2018 A3L04_05990 816e553fcd30bd941257965fe8ae5455 556 Pfam PF01409 tRNA synthetases class II core domain (F) 360 547 2.3E-4 T 23-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 A3L04_05990 816e553fcd30bd941257965fe8ae5455 556 Gene3D G3DSA:3.30.56.10 1 80 3.1E-22 T 23-10-2018 A3L04_05990 816e553fcd30bd941257965fe8ae5455 556 Hamap MF_00284 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 551 36.459 T 23-10-2018 IPR022918 Phenylalanine-tRNA ligase beta chain 2, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 A3L04_05990 816e553fcd30bd941257965fe8ae5455 556 SUPERFAMILY SSF56037 142 256 1.26E-6 T 23-10-2018 A3L04_05990 816e553fcd30bd941257965fe8ae5455 556 SMART SM00873 100 259 4.7E-22 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A3L04_05990 816e553fcd30bd941257965fe8ae5455 556 TIGRFAM TIGR00471 pheT_arch: phenylalanine--tRNA ligase, beta subunit 1 548 1.1E-183 T 23-10-2018 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A3L04_05990 816e553fcd30bd941257965fe8ae5455 556 Gene3D G3DSA:3.50.40.10 81 278 1.3E-75 T 23-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 A3L04_05990 816e553fcd30bd941257965fe8ae5455 556 Pfam PF03484 tRNA synthetase B5 domain 284 348 1.1E-13 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A3L04_05925 dc8d91bc8be215eac301bee53d01cc84 313 Pfam PF04473 Transglutaminase-like domain 55 183 1.6E-35 T 23-10-2018 IPR007562 Transglutaminase-like domain A3L04_05925 dc8d91bc8be215eac301bee53d01cc84 313 Gene3D G3DSA:3.10.620.30 25 157 8.6E-6 T 23-10-2018 A3L04_05925 dc8d91bc8be215eac301bee53d01cc84 313 SUPERFAMILY SSF54001 42 128 2.84E-5 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A3L04_03375 977cb875269c7b4543d52e58574cbb6c 359 Gene3D G3DSA:2.40.30.10 39 358 4.3E-118 T 23-10-2018 A3L04_03375 977cb875269c7b4543d52e58574cbb6c 359 Gene3D G3DSA:4.10.960.10 3 269 4.3E-118 T 23-10-2018 A3L04_03375 977cb875269c7b4543d52e58574cbb6c 359 ProSitePatterns PS00474 Ribosomal protein L3 signature. 208 231 - T 23-10-2018 IPR019926 Ribosomal protein L3, conserved site A3L04_03375 977cb875269c7b4543d52e58574cbb6c 359 Hamap MF_01325_A 50S ribosomal protein L3 [rplC]. 1 359 49.325 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_03375 977cb875269c7b4543d52e58574cbb6c 359 Pfam PF00297 Ribosomal protein L3 3 358 2.1E-93 T 23-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_03375 977cb875269c7b4543d52e58574cbb6c 359 SUPERFAMILY SSF50447 3 359 8.3E-92 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L04_03375 977cb875269c7b4543d52e58574cbb6c 359 Gene3D G3DSA:3.30.1430.10 77 202 4.3E-118 T 23-10-2018 A3L04_03375 977cb875269c7b4543d52e58574cbb6c 359 TIGRFAM TIGR03626 L3_arch: ribosomal protein uL3 5 358 7.7E-127 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_09930 563557dad405f5ccd1452ff3b38de019 406 Pfam PF01882 Protein of unknown function DUF58 187 265 4.4E-21 T 23-10-2018 IPR002881 Domain of unknown function DUF58 A3L04_00200 67a9644a5d230a99b5704b6aa5e1fca3 217 SUPERFAMILY SSF52540 92 184 3.4E-5 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_00200 67a9644a5d230a99b5704b6aa5e1fca3 217 Gene3D G3DSA:3.40.50.300 48 213 7.9E-6 T 23-10-2018 A3L04_07230 fe81defa4b8d3fc66aad236a4a93a5f3 688 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 72 103 0.035 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 A3L04_07230 fe81defa4b8d3fc66aad236a4a93a5f3 688 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 137 161 6.8 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 A3L04_07230 fe81defa4b8d3fc66aad236a4a93a5f3 688 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 281 314 0.034 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 A3L04_07230 fe81defa4b8d3fc66aad236a4a93a5f3 688 Gene3D G3DSA:1.50.10.20 241 434 1.5E-8 T 23-10-2018 A3L04_07230 fe81defa4b8d3fc66aad236a4a93a5f3 688 ProSitePatterns PS00018 EF-hand calcium-binding domain. 671 683 - T 23-10-2018 IPR018247 EF-Hand 1, calcium-binding site A3L04_07230 fe81defa4b8d3fc66aad236a4a93a5f3 688 SUPERFAMILY SSF48239 350 483 1.92E-6 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L04_07230 fe81defa4b8d3fc66aad236a4a93a5f3 688 Gene3D G3DSA:1.50.10.20 32 178 8.8E-11 T 23-10-2018 A3L04_07230 fe81defa4b8d3fc66aad236a4a93a5f3 688 SUPERFAMILY SSF48239 65 426 2.58E-23 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L04_07020 e014c7c80219d0d6d78d59b6d50a7d48 332 Pfam PF12679 ABC-2 family transporter protein 6 331 1.3E-47 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A3L04_04565 c778bdb390ad10f353eb6e866832ab13 172 Gene3D G3DSA:3.10.580.10 11 155 2.0E-19 T 23-10-2018 A3L04_04565 c778bdb390ad10f353eb6e866832ab13 172 PIRSF PIRSF019454 1 162 1.3E-86 T 23-10-2018 IPR016761 Uncharacterised conserved protein UCP019454, CBS A3L04_04565 c778bdb390ad10f353eb6e866832ab13 172 SUPERFAMILY SSF54631 5 152 3.54E-23 T 23-10-2018 A3L04_04565 c778bdb390ad10f353eb6e866832ab13 172 Pfam PF00571 CBS domain 96 144 2.2E-9 T 23-10-2018 IPR000644 CBS domain A3L04_04565 c778bdb390ad10f353eb6e866832ab13 172 Pfam PF00571 CBS domain 23 71 1.8E-5 T 23-10-2018 IPR000644 CBS domain A3L04_04565 c778bdb390ad10f353eb6e866832ab13 172 SMART SM00116 24 72 0.3 T 23-10-2018 IPR000644 CBS domain A3L04_04565 c778bdb390ad10f353eb6e866832ab13 172 SMART SM00116 103 151 6.6E-6 T 23-10-2018 IPR000644 CBS domain A3L04_01330 387e601b8d77b0b6fdc0bc96560bbf82 281 Pfam PF01972 Serine dehydrogenase proteinase 1 278 2.0E-153 T 23-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 A3L04_01330 387e601b8d77b0b6fdc0bc96560bbf82 281 Gene3D G3DSA:3.90.226.10 62 268 4.1E-24 T 23-10-2018 A3L04_01330 387e601b8d77b0b6fdc0bc96560bbf82 281 SUPERFAMILY SSF52096 12 240 1.99E-30 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L04_05015 abda541e14e5f4f3e409026d16e4eb1d 299 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 2 296 37.58 T 23-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 A3L04_05015 abda541e14e5f4f3e409026d16e4eb1d 299 PIRSF PIRSF000164 1 298 6.2E-92 T 23-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 A3L04_05015 abda541e14e5f4f3e409026d16e4eb1d 299 Gene3D G3DSA:3.20.20.70 10 287 2.2E-97 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_05015 abda541e14e5f4f3e409026d16e4eb1d 299 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 38 57 - T 23-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A3L04_05015 abda541e14e5f4f3e409026d16e4eb1d 299 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 233 253 - T 23-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A3L04_05015 abda541e14e5f4f3e409026d16e4eb1d 299 Gene3D G3DSA:2.30.26.10 53 210 2.2E-97 T 23-10-2018 IPR023359 Dihydroorotate dehydrogenase A, chain A, domain 2 A3L04_05015 abda541e14e5f4f3e409026d16e4eb1d 299 Pfam PF01180 Dihydroorotate dehydrogenase 1 281 2.5E-68 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A3L04_05015 abda541e14e5f4f3e409026d16e4eb1d 299 SUPERFAMILY SSF51395 2 297 2.6E-84 T 23-10-2018 A3L04_05015 abda541e14e5f4f3e409026d16e4eb1d 299 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 2 296 1.6E-134 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A3L04_02905 c86c5e3d1550c1e10abe7eb75114ac2e 267 Gene3D G3DSA:3.40.50.10320 1 267 5.2E-112 T 23-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A3L04_02905 c86c5e3d1550c1e10abe7eb75114ac2e 267 Pfam PF02585 GlcNAc-PI de-N-acetylase 35 161 8.3E-32 T 23-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A3L04_02905 c86c5e3d1550c1e10abe7eb75114ac2e 267 SUPERFAMILY SSF102588 32 256 3.92E-61 T 23-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A3L04_10455 26f865e7e807760f9f345157a3d12332 620 SUPERFAMILY SSF82171 23 351 9.55E-20 T 23-10-2018 A3L04_10455 26f865e7e807760f9f345157a3d12332 620 Gene3D G3DSA:2.120.10.30 22 134 2.8E-11 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A3L04_10455 26f865e7e807760f9f345157a3d12332 620 Gene3D G3DSA:3.40.50.1820 353 620 4.9E-83 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L04_10455 26f865e7e807760f9f345157a3d12332 620 SUPERFAMILY SSF53474 290 612 1.54E-58 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L04_10455 26f865e7e807760f9f345157a3d12332 620 Pfam PF07676 WD40-like Beta Propeller Repeat 60 77 0.0021 T 23-10-2018 IPR011659 WD40-like Beta Propeller A3L04_10455 26f865e7e807760f9f345157a3d12332 620 Pfam PF00326 Prolyl oligopeptidase family 396 607 7.1E-52 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A3L04_05475 012c40be643fc311ba558841b7613991 289 Pfam PF16916 Dimerisation domain of Zinc Transporter 207 275 2.5E-10 T 23-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain A3L04_05475 012c40be643fc311ba558841b7613991 289 Gene3D G3DSA:3.30.70.1350 199 277 5.7E-6 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A3L04_05475 012c40be643fc311ba558841b7613991 289 SUPERFAMILY SSF161111 4 199 1.03E-54 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A3L04_05475 012c40be643fc311ba558841b7613991 289 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 4 277 3.3E-88 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A3L04_05475 012c40be643fc311ba558841b7613991 289 Gene3D G3DSA:1.20.1510.10 2 198 8.6E-46 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A3L04_05475 012c40be643fc311ba558841b7613991 289 Pfam PF01545 Cation efflux family 7 198 1.1E-47 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A3L04_05475 012c40be643fc311ba558841b7613991 289 SUPERFAMILY SSF160240 202 275 9.16E-14 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A3L04_10535 575844e520867eae02796de67763a8f2 569 Pfam PF00482 Type II secretion system (T2SS), protein F 337 461 2.7E-10 T 23-10-2018 IPR018076 Type II secretion system F domain A3L04_10535 575844e520867eae02796de67763a8f2 569 Pfam PF00482 Type II secretion system (T2SS), protein F 88 213 1.2E-7 T 23-10-2018 IPR018076 Type II secretion system F domain A3L04_10475 39ac96ccb83efa5392f42ec246fd53b8 337 Gene3D G3DSA:1.25.40.10 3 74 8.9E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L04_01480 859cbf2b37994857c62c81fbe5d199fd 228 TIGRFAM TIGR02237 recomb_radB: DNA repair and recombination protein RadB 19 224 6.1E-79 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 A3L04_01480 859cbf2b37994857c62c81fbe5d199fd 228 Pfam PF08423 Rad51 11 225 3.0E-34 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 A3L04_01480 859cbf2b37994857c62c81fbe5d199fd 228 PIRSF PIRSF003336 7 227 2.3E-106 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 A3L04_01480 859cbf2b37994857c62c81fbe5d199fd 228 SMART SM00382 29 186 2.6E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_01480 859cbf2b37994857c62c81fbe5d199fd 228 Hamap MF_00350 DNA repair and recombination protein RadB [radB]. 18 224 38.008 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 A3L04_01480 859cbf2b37994857c62c81fbe5d199fd 228 Gene3D G3DSA:3.40.50.300 17 227 1.1E-57 T 23-10-2018 A3L04_01480 859cbf2b37994857c62c81fbe5d199fd 228 PRINTS PR01874 DNA repair protein radA signature 21 49 1.8E-8 T 23-10-2018 A3L04_01480 859cbf2b37994857c62c81fbe5d199fd 228 PRINTS PR01874 DNA repair protein radA signature 122 146 1.8E-8 T 23-10-2018 A3L04_01480 859cbf2b37994857c62c81fbe5d199fd 228 PRINTS PR01874 DNA repair protein radA signature 197 223 1.8E-8 T 23-10-2018 A3L04_01480 859cbf2b37994857c62c81fbe5d199fd 228 SUPERFAMILY SSF52540 10 227 1.8E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_04155 7a7330a9266a23583671f9ee994f35b1 417 SUPERFAMILY SSF52540 12 157 1.8E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_04155 7a7330a9266a23583671f9ee994f35b1 417 ProSitePatterns PS00018 EF-hand calcium-binding domain. 53 65 - T 23-10-2018 IPR018247 EF-Hand 1, calcium-binding site A3L04_05200 73f321b0d7df7d604d570d50699166d7 391 SUPERFAMILY SSF53187 7 168 7.61E-34 T 23-10-2018 A3L04_05200 73f321b0d7df7d604d570d50699166d7 391 Gene3D G3DSA:3.40.630.10 9 286 1.1E-34 T 23-10-2018 A3L04_05200 73f321b0d7df7d604d570d50699166d7 391 Pfam PF00246 Zinc carboxypeptidase 26 159 1.1E-16 T 23-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A3L04_05465 f8fa1991c82af47f1b46e5125477840a 342 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 83 97 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site A3L04_05465 f8fa1991c82af47f1b46e5125477840a 342 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 210 222 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site A3L04_05465 f8fa1991c82af47f1b46e5125477840a 342 Gene3D G3DSA:1.10.600.10 1 342 7.8E-140 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily A3L04_05465 f8fa1991c82af47f1b46e5125477840a 342 Pfam PF00348 Polyprenyl synthetase 33 270 4.9E-70 T 23-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 A3L04_05465 f8fa1991c82af47f1b46e5125477840a 342 SUPERFAMILY SSF48576 4 341 7.59E-96 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily A3L04_02780 0ab5c92deb32ddb106ec43d97b4e54e2 99 TIGRFAM TIGR02579 cas_csx3: CRISPR-associated protein, Csx3 family 12 92 4.7E-34 T 23-10-2018 IPR013409 CRISPR-associated protein Csx3 A3L04_02780 0ab5c92deb32ddb106ec43d97b4e54e2 99 Pfam PF09620 CRISPR-associated protein (Cas_csx3) 16 91 5.3E-32 T 23-10-2018 IPR013409 CRISPR-associated protein Csx3 A3L04_01175 133fdb2da7d0590558fcb3350f274982 817 SUPERFAMILY SSF56059 2 405 4.24E-105 T 23-10-2018 A3L04_01175 133fdb2da7d0590558fcb3350f274982 817 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 718 733 1.8E-13 T 23-10-2018 A3L04_01175 133fdb2da7d0590558fcb3350f274982 817 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 754 766 1.8E-13 T 23-10-2018 A3L04_01175 133fdb2da7d0590558fcb3350f274982 817 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 537 556 1.8E-13 T 23-10-2018 A3L04_01175 133fdb2da7d0590558fcb3350f274982 817 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 701 716 1.8E-13 T 23-10-2018 A3L04_01175 133fdb2da7d0590558fcb3350f274982 817 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 701 719 - T 23-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 A3L04_01175 133fdb2da7d0590558fcb3350f274982 817 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 436 447 - T 23-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 A3L04_01175 133fdb2da7d0590558fcb3350f274982 817 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 89 796 2.0E-269 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 A3L04_01175 133fdb2da7d0590558fcb3350f274982 817 Pfam PF00391 PEP-utilising enzyme, mobile domain 405 477 4.0E-28 T 23-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A3L04_01175 133fdb2da7d0590558fcb3350f274982 817 PIRSF PIRSF000854 1 800 1.1E-201 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 A3L04_01175 133fdb2da7d0590558fcb3350f274982 817 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 506 795 1.7E-98 T 23-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A3L04_01175 133fdb2da7d0590558fcb3350f274982 817 Gene3D G3DSA:3.30.470.20 223 378 1.7E-54 T 23-10-2018 A3L04_01175 133fdb2da7d0590558fcb3350f274982 817 SUPERFAMILY SSF52009 377 485 2.22E-36 T 23-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 A3L04_01175 133fdb2da7d0590558fcb3350f274982 817 Gene3D G3DSA:3.50.30.10 379 483 1.5E-42 T 23-10-2018 A3L04_01175 133fdb2da7d0590558fcb3350f274982 817 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 375 2.7E-117 T 23-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 A3L04_01175 133fdb2da7d0590558fcb3350f274982 817 Gene3D G3DSA:3.20.20.60 484 816 2.5E-105 T 23-10-2018 A3L04_01175 133fdb2da7d0590558fcb3350f274982 817 SUPERFAMILY SSF51621 510 803 8.38E-96 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A3L04_09990 cbf18cc77a10bb9330dfd935d066f941 218 Pfam PF02361 Cobalt transport protein 4 193 9.9E-27 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component A3L04_08040 06c1836e7a3b898998b5495772e11fe2 271 Gene3D G3DSA:3.40.50.12280 1 167 2.1E-41 T 23-10-2018 A3L04_08040 06c1836e7a3b898998b5495772e11fe2 271 SUPERFAMILY SSF56770 3 160 4.32E-44 T 23-10-2018 A3L04_08040 06c1836e7a3b898998b5495772e11fe2 271 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 16 144 7.8E-25 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_00500 6c7af204cd8189acd96aafaa5b8a4405 571 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 30 138 3.5E-18 T 23-10-2018 IPR029095 NarX-like, N-terminal A3L04_00500 6c7af204cd8189acd96aafaa5b8a4405 571 SMART SM00283 294 555 1.3E-55 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A3L04_00500 6c7af204cd8189acd96aafaa5b8a4405 571 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 354 501 1.3E-39 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A3L04_00500 6c7af204cd8189acd96aafaa5b8a4405 571 SUPERFAMILY SSF58104 241 568 3.49E-59 T 23-10-2018 A3L04_00500 6c7af204cd8189acd96aafaa5b8a4405 571 Gene3D G3DSA:1.10.287.950 261 569 6.3E-62 T 23-10-2018 A3L04_05205 eb9e690af43e9844f474974699fa65f8 309 Pfam PF13527 Acetyltransferase (GNAT) domain 7 134 3.5E-16 T 23-10-2018 A3L04_05205 eb9e690af43e9844f474974699fa65f8 309 SUPERFAMILY SSF55729 2 264 9.09E-34 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L04_05205 eb9e690af43e9844f474974699fa65f8 309 Gene3D G3DSA:3.40.630.30 3 135 1.1E-18 T 23-10-2018 A3L04_05060 651ac573098c6f742b5d73fcbcc94f58 53 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 23-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 A3L04_05060 651ac573098c6f742b5d73fcbcc94f58 53 Gene3D G3DSA:2.20.28.10 1 53 1.8E-29 T 23-10-2018 A3L04_05060 651ac573098c6f742b5d73fcbcc94f58 53 PIRSF PIRSF000071 1 53 1.3E-28 T 23-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 A3L04_05060 651ac573098c6f742b5d73fcbcc94f58 53 Pfam PF00301 Rubredoxin 3 49 5.2E-26 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 A3L04_05060 651ac573098c6f742b5d73fcbcc94f58 53 SUPERFAMILY SSF57802 1 52 5.22E-25 T 23-10-2018 A3L04_05060 651ac573098c6f742b5d73fcbcc94f58 53 PRINTS PR00163 Rubredoxin signature 3 19 1.8E-12 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 A3L04_05060 651ac573098c6f742b5d73fcbcc94f58 53 PRINTS PR00163 Rubredoxin signature 33 49 1.8E-12 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 A3L04_00835 ce5504a2355549640ffe5ca7266cac48 199 Hamap MF_00359 30S ribosomal protein S3Ae [rps3ae]. 5 195 37.112 T 23-10-2018 IPR030838 30S ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 A3L04_00835 ce5504a2355549640ffe5ca7266cac48 199 ProSitePatterns PS01191 Ribosomal protein S3Ae signature. 44 56 - T 23-10-2018 IPR018281 Ribosomal protein S3Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_00835 ce5504a2355549640ffe5ca7266cac48 199 SMART SM01397 5 195 4.3E-102 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_00835 ce5504a2355549640ffe5ca7266cac48 199 Pfam PF01015 Ribosomal S3Ae family 9 195 2.3E-67 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_02330 74cba8f052241301aae3dbe05fc98f05 150 Gene3D G3DSA:1.10.10.10 2 56 1.2E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_02330 74cba8f052241301aae3dbe05fc98f05 150 Gene3D G3DSA:3.30.70.920 59 150 2.8E-25 T 23-10-2018 A3L04_02330 74cba8f052241301aae3dbe05fc98f05 150 SUPERFAMILY SSF54909 65 147 1.34E-18 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L04_02330 74cba8f052241301aae3dbe05fc98f05 150 SUPERFAMILY SSF46785 4 63 2.86E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_02330 74cba8f052241301aae3dbe05fc98f05 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 52 9.6E-15 T 23-10-2018 A3L04_02330 74cba8f052241301aae3dbe05fc98f05 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 5.1E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_02330 74cba8f052241301aae3dbe05fc98f05 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 5.1E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_02330 74cba8f052241301aae3dbe05fc98f05 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 5.1E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_02330 74cba8f052241301aae3dbe05fc98f05 150 SMART SM00344 5 114 3.8E-49 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L04_02330 74cba8f052241301aae3dbe05fc98f05 150 Pfam PF01037 Lrp/AsnC ligand binding domain 71 142 1.1E-15 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L04_02155 4984150fa1db86f428b205b365616a79 274 SUPERFAMILY SSF52440 3 83 7.77E-21 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L04_02155 4984150fa1db86f428b205b365616a79 274 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 4 268 9.0E-86 T 23-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 A3L04_02155 4984150fa1db86f428b205b365616a79 274 Gene3D G3DSA:3.30.1490.20 98 166 6.2E-30 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L04_02155 4984150fa1db86f428b205b365616a79 274 Gene3D G3DSA:3.30.470.80 167 274 1.9E-38 T 23-10-2018 A3L04_02155 4984150fa1db86f428b205b365616a79 274 TIGRFAM TIGR02144 LysX_arch: lysine biosynthesis enzyme LysX 4 273 7.2E-108 T 23-10-2018 IPR011870 Lysine biosynthesis enzyme LysX GO:0003824|GO:0005524|GO:0009085 A3L04_02155 4984150fa1db86f428b205b365616a79 274 Gene3D G3DSA:3.40.50.20 2 97 1.2E-32 T 23-10-2018 A3L04_02155 4984150fa1db86f428b205b365616a79 274 Pfam PF08443 RimK-like ATP-grasp domain 84 267 9.3E-24 T 23-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 A3L04_02155 4984150fa1db86f428b205b365616a79 274 SUPERFAMILY SSF56059 82 270 2.02E-40 T 23-10-2018 A3L04_03050 c4c6056ed0fdf61dfd8cdd560668f3f3 167 SUPERFAMILY SSF49764 33 158 8.11E-34 T 23-10-2018 IPR008978 HSP20-like chaperone A3L04_03050 c4c6056ed0fdf61dfd8cdd560668f3f3 167 Pfam PF00011 Hsp20/alpha crystallin family 63 158 1.6E-20 T 23-10-2018 IPR002068 Alpha crystallin/Hsp20 domain A3L04_03050 c4c6056ed0fdf61dfd8cdd560668f3f3 167 Gene3D G3DSA:2.60.40.790 13 160 1.6E-33 T 23-10-2018 IPR008978 HSP20-like chaperone A3L04_06470 f6f07c3bd9513e86fa52bdc8b29db94f 263 Gene3D G3DSA:1.10.443.10 91 258 2.4E-37 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A3L04_06470 f6f07c3bd9513e86fa52bdc8b29db94f 263 Pfam PF16795 Archaeal phage integrase 93 254 7.8E-45 T 23-10-2018 IPR031857 Integrase SSV1, C-terminal A3L04_06470 f6f07c3bd9513e86fa52bdc8b29db94f 263 SUPERFAMILY SSF56349 3 241 3.0E-10 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A3L04_04430 90c2954294779fe1ffb163378988208b 143 SUPERFAMILY SSF82784 9 140 2.49E-32 T 23-10-2018 IPR036102 OsmC/Ohr superfamily A3L04_04430 90c2954294779fe1ffb163378988208b 143 Pfam PF02566 OsmC-like protein 36 138 3.2E-21 T 23-10-2018 IPR003718 OsmC/Ohr family A3L04_04430 90c2954294779fe1ffb163378988208b 143 Gene3D G3DSA:3.30.300.20 3 142 2.8E-31 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L04_07800 1c5232c224ddbacc02e965482c28d407 109 SUPERFAMILY SSF110857 1 96 1.7E-19 T 23-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily A3L04_07800 1c5232c224ddbacc02e965482c28d407 109 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 5 107 1.2E-11 T 23-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like A3L04_07800 1c5232c224ddbacc02e965482c28d407 109 Gene3D G3DSA:3.10.490.10 1 109 1.6E-31 T 23-10-2018 A3L04_03385 19c6bcac20b21ce34e4c307b07801e0d 86 SUPERFAMILY SSF54189 1 80 7.19E-29 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_03385 19c6bcac20b21ce34e4c307b07801e0d 86 Pfam PF00276 Ribosomal protein L23 5 73 2.5E-20 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A3L04_03385 19c6bcac20b21ce34e4c307b07801e0d 86 Hamap MF_01369_A 50S ribosomal protein L23 [rplW]. 6 86 28.68 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A3L04_03385 19c6bcac20b21ce34e4c307b07801e0d 86 ProSitePatterns PS00050 Ribosomal protein L23 signature. 64 79 - T 23-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03385 19c6bcac20b21ce34e4c307b07801e0d 86 TIGRFAM TIGR03636 uL23_arch: ribosomal protein uL23 10 86 4.6E-40 T 23-10-2018 IPR019985 Ribosomal protein L23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03385 19c6bcac20b21ce34e4c307b07801e0d 86 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 82 15.4 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A3L04_03385 19c6bcac20b21ce34e4c307b07801e0d 86 Gene3D G3DSA:3.30.70.330 1 86 2.0E-37 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily A3L04_01700 f7ed8702e3aefc385c58d37ac4f876dc 321 Gene3D G3DSA:1.20.120.420 1 113 1.1E-41 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L04_01700 f7ed8702e3aefc385c58d37ac4f876dc 321 Pfam PF01008 Initiation factor 2 subunit family 17 298 2.0E-95 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A3L04_01700 f7ed8702e3aefc385c58d37ac4f876dc 321 Gene3D G3DSA:3.40.50.10470 114 309 4.5E-86 T 23-10-2018 A3L04_01700 f7ed8702e3aefc385c58d37ac4f876dc 321 TIGRFAM TIGR00511 ribulose_e2b2: ribose-1,5-bisphosphate isomerase, e2b2 family 5 311 3.9E-152 T 23-10-2018 IPR005250 Ribose-1,5-bisphosphate isomerase, e2b2 family MetaCyc: PWY-5532 A3L04_01700 f7ed8702e3aefc385c58d37ac4f876dc 321 SUPERFAMILY SSF100950 2 310 1.19E-101 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L04_01700 f7ed8702e3aefc385c58d37ac4f876dc 321 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 4 298 1.8E-99 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L04_00815 c1517adf5730cdb1b02953551408fba3 164 Pfam PF01230 HIT domain 34 125 5.5E-15 T 23-10-2018 IPR001310 Histidine triad (HIT) protein A3L04_00815 c1517adf5730cdb1b02953551408fba3 164 SUPERFAMILY SSF54197 1 161 3.25E-48 T 23-10-2018 IPR036265 HIT-like superfamily A3L04_00815 c1517adf5730cdb1b02953551408fba3 164 Gene3D G3DSA:3.30.428.10 1 163 1.9E-58 T 23-10-2018 IPR036265 HIT-like superfamily A3L04_05980 cf580dd907a7542f8862793c8c8f9fe2 212 Hamap MF_01285 Riboflavin kinase [ribK]. 88 211 25.489 T 23-10-2018 IPR023470 Riboflavin kinase, archaeal GO:0008531|GO:0009231 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 A3L04_05980 cf580dd907a7542f8862793c8c8f9fe2 212 Pfam PF13545 Crp-like helix-turn-helix domain 8 69 4.1E-7 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L04_05980 cf580dd907a7542f8862793c8c8f9fe2 212 Gene3D G3DSA:1.10.10.10 2 85 2.2E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_05980 cf580dd907a7542f8862793c8c8f9fe2 212 Gene3D G3DSA:2.40.30.30 87 212 3.3E-40 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 A3L04_05980 cf580dd907a7542f8862793c8c8f9fe2 212 SUPERFAMILY SSF82114 90 211 1.08E-40 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 A3L04_05980 cf580dd907a7542f8862793c8c8f9fe2 212 SUPERFAMILY SSF46785 6 81 1.6E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_05980 cf580dd907a7542f8862793c8c8f9fe2 212 Pfam PF01982 Domain of unknown function DUF120 94 210 5.4E-38 T 23-10-2018 IPR023602 Riboflavin kinase domain, CTP-dependent GO:0016773 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 A3L04_10715 4ecfeaa6060b5ca48e20393e8eccdb7b 264 Pfam PF13344 Haloacid dehalogenase-like hydrolase 4 103 3.0E-31 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A3L04_10715 4ecfeaa6060b5ca48e20393e8eccdb7b 264 TIGRFAM TIGR01452 PGP_euk: phosphoglycolate/pyridoxal phosphate phosphatase family 3 252 6.5E-61 T 23-10-2018 IPR006349 2-phosphoglycolate phosphatase, eukaryotic GO:0016791 A3L04_10715 4ecfeaa6060b5ca48e20393e8eccdb7b 264 Gene3D G3DSA:3.40.50.1000 69 185 5.0E-100 T 23-10-2018 IPR023214 HAD superfamily A3L04_10715 4ecfeaa6060b5ca48e20393e8eccdb7b 264 Pfam PF13242 HAD-hyrolase-like 185 254 1.3E-21 T 23-10-2018 A3L04_10715 4ecfeaa6060b5ca48e20393e8eccdb7b 264 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 4 232 2.8E-50 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A3L04_10715 4ecfeaa6060b5ca48e20393e8eccdb7b 264 PIRSF PIRSF000915 3 262 2.0E-71 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A3L04_10715 4ecfeaa6060b5ca48e20393e8eccdb7b 264 Gene3D G3DSA:3.40.50.1000 5 250 5.0E-100 T 23-10-2018 IPR023214 HAD superfamily A3L04_10715 4ecfeaa6060b5ca48e20393e8eccdb7b 264 SUPERFAMILY SSF56784 3 257 8.68E-73 T 23-10-2018 IPR036412 HAD-like superfamily A3L04_10715 4ecfeaa6060b5ca48e20393e8eccdb7b 264 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 185 223 6.9E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_02180 9c7ad90c5728d03d4b053d5bc0f1bf1a 775 Gene3D G3DSA:3.30.342.10 3 366 6.7E-173 T 23-10-2018 A3L04_02180 9c7ad90c5728d03d4b053d5bc0f1bf1a 775 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 447 747 6.1E-119 T 23-10-2018 A3L04_02180 9c7ad90c5728d03d4b053d5bc0f1bf1a 775 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 2 490 1.4E-110 T 23-10-2018 A3L04_02180 9c7ad90c5728d03d4b053d5bc0f1bf1a 775 SUPERFAMILY SSF56672 349 756 3.0E-128 T 23-10-2018 A3L04_02180 9c7ad90c5728d03d4b053d5bc0f1bf1a 775 Gene3D G3DSA:1.10.132.60 608 774 3.8E-60 T 23-10-2018 A3L04_02180 9c7ad90c5728d03d4b053d5bc0f1bf1a 775 ProSitePatterns PS00116 DNA polymerase family B signature. 539 547 - T 23-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L04_02180 9c7ad90c5728d03d4b053d5bc0f1bf1a 775 Pfam PF00136 DNA polymerase family B 350 748 1.2E-78 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L04_02180 9c7ad90c5728d03d4b053d5bc0f1bf1a 775 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 484 496 2.8E-9 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L04_02180 9c7ad90c5728d03d4b053d5bc0f1bf1a 775 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 537 545 2.8E-9 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L04_02180 9c7ad90c5728d03d4b053d5bc0f1bf1a 775 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 401 414 2.8E-9 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L04_02180 9c7ad90c5728d03d4b053d5bc0f1bf1a 775 SUPERFAMILY SSF53098 1 346 3.08E-92 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily A3L04_02180 9c7ad90c5728d03d4b053d5bc0f1bf1a 775 Gene3D G3DSA:1.10.287.690 449 500 9.2E-24 T 23-10-2018 A3L04_02180 9c7ad90c5728d03d4b053d5bc0f1bf1a 775 Pfam PF03104 DNA polymerase family B, exonuclease domain 22 129 3.7E-14 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L04_02180 9c7ad90c5728d03d4b053d5bc0f1bf1a 775 Pfam PF03104 DNA polymerase family B, exonuclease domain 130 278 9.1E-38 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L04_02180 9c7ad90c5728d03d4b053d5bc0f1bf1a 775 SMART SM00486 133 551 3.0E-140 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L04_02180 9c7ad90c5728d03d4b053d5bc0f1bf1a 775 Gene3D G3DSA:3.30.420.10 131 347 6.7E-173 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A3L04_07030 747873d21270a36deb24ed5905fc16da 305 SUPERFAMILY SSF52540 3 225 3.22E-62 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_07030 747873d21270a36deb24ed5905fc16da 305 Pfam PF13732 Domain of unknown function (DUF4162) 216 300 2.4E-10 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 A3L04_07030 747873d21270a36deb24ed5905fc16da 305 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_07030 747873d21270a36deb24ed5905fc16da 305 SMART SM00382 28 211 1.6E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_07030 747873d21270a36deb24ed5905fc16da 305 Pfam PF00005 ABC transporter 19 163 2.6E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_07030 747873d21270a36deb24ed5905fc16da 305 Gene3D G3DSA:3.40.50.300 1 238 1.7E-68 T 23-10-2018 A3L04_07665 6c6c3006169488bfe7cb39a1c85d43f9 341 SUPERFAMILY SSF88723 7 236 5.89E-67 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_07665 6c6c3006169488bfe7cb39a1c85d43f9 341 Gene3D G3DSA:1.10.150.20 221 281 3.5E-22 T 23-10-2018 A3L04_07665 6c6c3006169488bfe7cb39a1c85d43f9 341 Pfam PF00752 XPG N-terminal domain 12 101 6.6E-23 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 A3L04_07665 6c6c3006169488bfe7cb39a1c85d43f9 341 Gene3D G3DSA:3.40.50.1010 1 220 1.2E-90 T 23-10-2018 A3L04_07665 6c6c3006169488bfe7cb39a1c85d43f9 341 SMART SM00484 140 221 2.0E-36 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 A3L04_07665 6c6c3006169488bfe7cb39a1c85d43f9 341 TIGRFAM TIGR03674 fen_arch: flap structure-specific endonuclease 1 338 2.4E-158 T 23-10-2018 IPR019973 Flap structure-specific endonuclease, archaea GO:0016788 A3L04_07665 6c6c3006169488bfe7cb39a1c85d43f9 341 SMART SM00485 1 101 5.3E-51 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 A3L04_07665 6c6c3006169488bfe7cb39a1c85d43f9 341 Pfam PF00867 XPG I-region 141 236 3.4E-29 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 A3L04_07665 6c6c3006169488bfe7cb39a1c85d43f9 341 SMART SM00279 223 257 1.1E-11 T 23-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 A3L04_07665 6c6c3006169488bfe7cb39a1c85d43f9 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 75 94 4.7E-34 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L04_07665 6c6c3006169488bfe7cb39a1c85d43f9 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 139 156 4.7E-34 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L04_07665 6c6c3006169488bfe7cb39a1c85d43f9 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 160 180 4.7E-34 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L04_07665 6c6c3006169488bfe7cb39a1c85d43f9 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 21 35 4.7E-34 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L04_07665 6c6c3006169488bfe7cb39a1c85d43f9 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 226 241 4.7E-34 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L04_07665 6c6c3006169488bfe7cb39a1c85d43f9 341 Hamap MF_00614 Flap endonuclease 1 [fen]. 1 340 148.419 T 23-10-2018 IPR023426 Flap endonuclease 1 GO:0016788 Reactome: R-HSA-110362|Reactome: R-HSA-162594|Reactome: R-HSA-174437|Reactome: R-HSA-5651801|Reactome: R-HSA-5685939|Reactome: R-HSA-69166 A3L04_07665 6c6c3006169488bfe7cb39a1c85d43f9 341 SUPERFAMILY SSF47807 221 338 6.58E-33 T 23-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily A3L04_07665 6c6c3006169488bfe7cb39a1c85d43f9 341 ProSitePatterns PS00841 XPG protein signature 1. 73 87 - T 23-10-2018 IPR019974 XPG conserved site GO:0016788 A3L04_02445 55fd76f854716cc9f36b0c060561ef2d 172 Gene3D G3DSA:3.40.630.30 19 170 1.6E-48 T 23-10-2018 A3L04_02445 55fd76f854716cc9f36b0c060561ef2d 172 Pfam PF00583 Acetyltransferase (GNAT) family 38 140 2.1E-25 T 23-10-2018 IPR000182 GNAT domain A3L04_02445 55fd76f854716cc9f36b0c060561ef2d 172 SUPERFAMILY SSF55729 20 171 9.0E-40 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L04_02445 55fd76f854716cc9f36b0c060561ef2d 172 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 30 159 1.3E-34 T 23-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 A3L04_09150 0576dd4c4e00fbb3ff41ea3644af8ce5 329 Gene3D G3DSA:3.20.20.70 62 264 2.5E-17 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_09150 0576dd4c4e00fbb3ff41ea3644af8ce5 329 SUPERFAMILY SSF102114 69 293 9.68E-20 T 23-10-2018 A3L04_09150 0576dd4c4e00fbb3ff41ea3644af8ce5 329 PIRSF PIRSF004869 1 306 4.2E-65 T 23-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted A3L04_09150 0576dd4c4e00fbb3ff41ea3644af8ce5 329 Pfam PF04055 Radical SAM superfamily 80 226 1.3E-10 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_06585 089c37befa330adcd64a541f114c3fa1 218 Gene3D G3DSA:3.40.50.11570 3 214 2.1E-50 T 23-10-2018 A3L04_06585 089c37befa330adcd64a541f114c3fa1 218 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 7 210 1.6E-58 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L04_05130 6d96439a19d16483c6bb1a806bd773f0 254 TIGRFAM TIGR01247 drrB: daunorubicin resistance ABC transporter membrane protein 10 248 4.8E-123 T 23-10-2018 IPR005942 Daunorubicin resistance ABC transporter membrane protein A3L04_05130 6d96439a19d16483c6bb1a806bd773f0 254 Pfam PF01061 ABC-2 type transporter 4 216 5.4E-44 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A3L04_05130 6d96439a19d16483c6bb1a806bd773f0 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 195 214 3.4E-14 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L04_05130 6d96439a19d16483c6bb1a806bd773f0 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 22 43 3.4E-14 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L04_05130 6d96439a19d16483c6bb1a806bd773f0 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 175 194 3.4E-14 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L04_05130 6d96439a19d16483c6bb1a806bd773f0 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 138 162 3.4E-14 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L04_05130 6d96439a19d16483c6bb1a806bd773f0 254 PIRSF PIRSF006648 1 253 2.5E-70 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L04_01360 4dadc26ff7e072d279254ab58028214a 256 SUPERFAMILY SSF56281 1 256 9.96E-41 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_01360 4dadc26ff7e072d279254ab58028214a 256 Gene3D G3DSA:3.60.15.10 1 256 8.1E-46 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_01360 4dadc26ff7e072d279254ab58028214a 256 Pfam PF12706 Beta-lactamase superfamily domain 45 224 5.8E-22 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_01360 4dadc26ff7e072d279254ab58028214a 256 SMART SM00849 36 223 1.5E-10 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_08950 667ddac39a0632d7664a4be364ff4749 367 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 233 244 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_08950 667ddac39a0632d7664a4be364ff4749 367 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 312 323 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_08950 667ddac39a0632d7664a4be364ff4749 367 Pfam PF17179 4Fe-4S dicluster domain 232 326 9.7E-27 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L04_08950 667ddac39a0632d7664a4be364ff4749 367 SUPERFAMILY SSF46548 219 333 3.35E-12 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L04_04110 b80e6de4476248eae60e6a44ee046356 164 SUPERFAMILY SSF117457 4 163 1.83E-48 T 23-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 A3L04_04110 b80e6de4476248eae60e6a44ee046356 164 Gene3D G3DSA:3.20.130.10 1 164 3.5E-60 T 23-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 A3L04_04110 b80e6de4476248eae60e6a44ee046356 164 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 13 163 2.1E-47 T 23-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A3L04_04110 b80e6de4476248eae60e6a44ee046356 164 Pfam PF05683 Fumarase C-terminus 3 163 1.3E-35 T 23-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A3L04_08735 03dbe4182a46f6397706c4fa8e7cfbf0 165 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 2 135 6.0E-50 T 23-10-2018 A3L04_08735 03dbe4182a46f6397706c4fa8e7cfbf0 165 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 1 163 8.0E-26 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 A3L04_08735 03dbe4182a46f6397706c4fa8e7cfbf0 165 SMART SM01118 1 165 1.5E-14 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A3L04_08735 03dbe4182a46f6397706c4fa8e7cfbf0 165 Gene3D G3DSA:2.40.320.10 1 165 8.6E-53 T 23-10-2018 A3L04_08735 03dbe4182a46f6397706c4fa8e7cfbf0 165 SUPERFAMILY SSF55154 1 162 1.23E-41 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 A3L04_08735 03dbe4182a46f6397706c4fa8e7cfbf0 165 Pfam PF01928 CYTH domain 2 159 5.9E-31 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A3L04_02105 a0a36c674611049124e9694bf8705f0e 189 PIRSF PIRSF019325 1 189 6.8E-77 T 23-10-2018 IPR016758 Glucose-6-phosphate isomerase, archaea/bacteria GO:0004347|GO:0005506 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 A3L04_02105 a0a36c674611049124e9694bf8705f0e 189 Hamap MF_01410 Glucose-6-phosphate isomerase [pgiA]. 1 185 48.703 T 23-10-2018 IPR016758 Glucose-6-phosphate isomerase, archaea/bacteria GO:0004347|GO:0005506 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 A3L04_02105 a0a36c674611049124e9694bf8705f0e 189 Gene3D G3DSA:2.60.120.10 1 189 2.7E-78 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L04_02105 a0a36c674611049124e9694bf8705f0e 189 Pfam PF06560 Glucose-6-phosphate isomerase (GPI) 24 182 8.0E-41 T 23-10-2018 IPR010551 Glucose-6-phosphate isomerase, prokaryote GO:0004347|GO:0005737|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 A3L04_02105 a0a36c674611049124e9694bf8705f0e 189 SUPERFAMILY SSF51182 1 187 1.94E-48 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L04_03930 72b77d5f1e835200548a224f8110e929 208 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 1 206 30.693 T 23-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 A3L04_03930 72b77d5f1e835200548a224f8110e929 208 SUPERFAMILY SSF51366 1 205 1.57E-38 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L04_03930 72b77d5f1e835200548a224f8110e929 208 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 3 201 6.3E-29 T 23-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 A3L04_03930 72b77d5f1e835200548a224f8110e929 208 Gene3D G3DSA:3.20.20.70 1 208 1.4E-72 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_03765 d00458272e09c092526c17e21e8c6bc9 388 SUPERFAMILY SSF53383 2 387 8.11E-108 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L04_03765 d00458272e09c092526c17e21e8c6bc9 388 Pfam PF00155 Aminotransferase class I and II 49 365 5.1E-38 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L04_03765 d00458272e09c092526c17e21e8c6bc9 388 Gene3D G3DSA:3.40.640.10 59 280 3.7E-132 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L04_03765 d00458272e09c092526c17e21e8c6bc9 388 Gene3D G3DSA:3.90.1150.10 18 385 3.7E-132 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L04_00405 fab110843457f8dc2eae81ea43e5d880 152 SUPERFAMILY SSF50104 53 146 1.0E-17 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L04_00405 fab110843457f8dc2eae81ea43e5d880 152 SMART SM00738 2 86 5.8E-24 T 23-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A3L04_00405 fab110843457f8dc2eae81ea43e5d880 152 Gene3D G3DSA:2.30.30.30 87 152 1.5E-29 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L04_00405 fab110843457f8dc2eae81ea43e5d880 152 TIGRFAM TIGR00405 KOW_elon_Spt5: transcription elongation factor Spt5 6 149 5.8E-55 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 A3L04_00405 fab110843457f8dc2eae81ea43e5d880 152 Pfam PF00467 KOW motif 94 125 4.6E-9 T 23-10-2018 IPR005824 KOW A3L04_00405 fab110843457f8dc2eae81ea43e5d880 152 Hamap MF_00950 Transcription elongation factor Spt5 [spt5]. 4 147 40.025 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 A3L04_00405 fab110843457f8dc2eae81ea43e5d880 152 SMART SM00739 91 118 1.4E-6 T 23-10-2018 IPR005824 KOW A3L04_00405 fab110843457f8dc2eae81ea43e5d880 152 Pfam PF03439 Early transcription elongation factor of RNA pol II, NGN section 4 83 1.6E-26 T 23-10-2018 IPR005100 NGN domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A3L04_00405 fab110843457f8dc2eae81ea43e5d880 152 Gene3D G3DSA:3.30.70.940 1 86 4.7E-35 T 23-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A3L04_02305 205ee6e05b1835c60a8cb0a05cd40dff 385 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 73 380 6.4E-108 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L04_02305 205ee6e05b1835c60a8cb0a05cd40dff 385 SUPERFAMILY SSF52374 5 369 2.37E-91 T 23-10-2018 A3L04_02305 205ee6e05b1835c60a8cb0a05cd40dff 385 Hamap MF_00140_A Tryptophan--tRNA ligase [trpS]. 6 367 46.467 T 23-10-2018 IPR020653 Tryptophan-tRNA ligase, archaea GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L04_02305 205ee6e05b1835c60a8cb0a05cd40dff 385 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 86 102 1.9E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L04_02305 205ee6e05b1835c60a8cb0a05cd40dff 385 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 253 263 1.9E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L04_02305 205ee6e05b1835c60a8cb0a05cd40dff 385 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 209 230 1.9E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L04_02305 205ee6e05b1835c60a8cb0a05cd40dff 385 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 139 158 1.9E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L04_02305 205ee6e05b1835c60a8cb0a05cd40dff 385 Pfam PF00579 tRNA synthetases class I (W and Y) 74 348 7.9E-27 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_02305 205ee6e05b1835c60a8cb0a05cd40dff 385 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 82 91 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_02305 205ee6e05b1835c60a8cb0a05cd40dff 385 Gene3D G3DSA:1.10.240.10 257 385 7.3E-46 T 23-10-2018 A3L04_02305 205ee6e05b1835c60a8cb0a05cd40dff 385 Gene3D G3DSA:3.40.50.620 1 256 1.2E-104 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_07100 3a9a43140102b2101d26fdb414818807 335 ProSitePatterns PS01235 PdxS/SNZ family signature. 248 266 - T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L04_07100 3a9a43140102b2101d26fdb414818807 335 Pfam PF05690 Thiazole biosynthesis protein ThiG 245 299 6.1E-8 T 23-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A3L04_07100 3a9a43140102b2101d26fdb414818807 335 Pfam PF01680 SOR/SNZ family 13 213 2.9E-96 T 23-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L04_07100 3a9a43140102b2101d26fdb414818807 335 PIRSF PIRSF029271 2 335 2.2E-147 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L04_07100 3a9a43140102b2101d26fdb414818807 335 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 10 335 53.289 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L04_07100 3a9a43140102b2101d26fdb414818807 335 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 15 334 8.8E-145 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L04_07100 3a9a43140102b2101d26fdb414818807 335 Gene3D G3DSA:3.20.20.70 1 316 5.8E-157 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_07100 3a9a43140102b2101d26fdb414818807 335 SUPERFAMILY SSF51366 24 312 8.47E-61 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L04_04645 ab6f9f0872d6819b248792ef2cfc5a3f 169 PRINTS PR00502 NUDIX hydrolase family signature 82 97 6.1E-7 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A3L04_04645 ab6f9f0872d6819b248792ef2cfc5a3f 169 PRINTS PR00502 NUDIX hydrolase family signature 68 82 6.1E-7 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A3L04_04645 ab6f9f0872d6819b248792ef2cfc5a3f 169 Pfam PF00293 NUDIX domain 44 163 7.2E-22 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A3L04_04645 ab6f9f0872d6819b248792ef2cfc5a3f 169 SUPERFAMILY SSF55811 40 166 2.3E-31 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A3L04_04645 ab6f9f0872d6819b248792ef2cfc5a3f 169 ProSitePatterns PS00893 Nudix box signature. 73 94 - T 23-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A3L04_04645 ab6f9f0872d6819b248792ef2cfc5a3f 169 Gene3D G3DSA:3.90.79.10 39 168 3.8E-41 T 23-10-2018 A3L04_05845 09aa8dc7d2b644453fee51609eab9bd9 537 Gene3D G3DSA:3.10.580.10 479 535 7.5E-8 T 23-10-2018 A3L04_05845 09aa8dc7d2b644453fee51609eab9bd9 537 Pfam PF00654 Voltage gated chloride channel 53 387 4.0E-76 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A3L04_05845 09aa8dc7d2b644453fee51609eab9bd9 537 Pfam PF00571 CBS domain 482 521 3.4E-8 T 23-10-2018 IPR000644 CBS domain A3L04_05845 09aa8dc7d2b644453fee51609eab9bd9 537 Pfam PF00571 CBS domain 420 472 4.5E-7 T 23-10-2018 IPR000644 CBS domain A3L04_05845 09aa8dc7d2b644453fee51609eab9bd9 537 SUPERFAMILY SSF81340 4 408 4.71E-92 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 A3L04_05845 09aa8dc7d2b644453fee51609eab9bd9 537 Gene3D G3DSA:3.10.580.10 413 478 2.7E-9 T 23-10-2018 A3L04_05845 09aa8dc7d2b644453fee51609eab9bd9 537 SMART SM00116 427 475 1.1 T 23-10-2018 IPR000644 CBS domain A3L04_05845 09aa8dc7d2b644453fee51609eab9bd9 537 SMART SM00116 479 525 0.17 T 23-10-2018 IPR000644 CBS domain A3L04_05845 09aa8dc7d2b644453fee51609eab9bd9 537 PRINTS PR00762 Chloride channel signature 337 353 2.2E-18 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A3L04_05845 09aa8dc7d2b644453fee51609eab9bd9 537 PRINTS PR00762 Chloride channel signature 355 374 2.2E-18 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A3L04_05845 09aa8dc7d2b644453fee51609eab9bd9 537 PRINTS PR00762 Chloride channel signature 66 83 2.2E-18 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A3L04_05845 09aa8dc7d2b644453fee51609eab9bd9 537 PRINTS PR00762 Chloride channel signature 309 329 2.2E-18 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A3L04_05845 09aa8dc7d2b644453fee51609eab9bd9 537 PRINTS PR00762 Chloride channel signature 146 165 2.2E-18 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A3L04_05845 09aa8dc7d2b644453fee51609eab9bd9 537 SUPERFAMILY SSF54631 415 522 4.27E-22 T 23-10-2018 A3L04_05845 09aa8dc7d2b644453fee51609eab9bd9 537 Gene3D G3DSA:1.10.3080.10 2 408 1.7E-87 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 A3L04_01195 b3f6eef5563982049536339c9b527559 239 Pfam PF06508 Queuosine biosynthesis protein QueC 3 224 2.8E-63 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L04_01195 b3f6eef5563982049536339c9b527559 239 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 4 218 1.3E-49 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L04_01195 b3f6eef5563982049536339c9b527559 239 Gene3D G3DSA:3.40.50.620 1 234 8.4E-61 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_01195 b3f6eef5563982049536339c9b527559 239 PIRSF PIRSF006293 1 238 7.4E-70 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L04_01195 b3f6eef5563982049536339c9b527559 239 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 2 231 45.125 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L04_01195 b3f6eef5563982049536339c9b527559 239 SUPERFAMILY SSF52402 1 234 7.72E-50 T 23-10-2018 A3L04_04350 5958ff97369878dfbe83a584f20af472 137 Pfam PF00411 Ribosomal protein S11 15 133 7.7E-48 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A3L04_04350 5958ff97369878dfbe83a584f20af472 137 Gene3D G3DSA:3.30.420.80 1 137 4.7E-67 T 23-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 A3L04_04350 5958ff97369878dfbe83a584f20af472 137 SUPERFAMILY SSF53137 9 135 3.92E-40 T 23-10-2018 A3L04_04350 5958ff97369878dfbe83a584f20af472 137 TIGRFAM TIGR03628 arch_S11P: ribosomal protein uS11 13 129 2.4E-67 T 23-10-2018 IPR019961 Ribosomal protein S11, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_04350 5958ff97369878dfbe83a584f20af472 137 PIRSF PIRSF002131 1 136 2.7E-36 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A3L04_04350 5958ff97369878dfbe83a584f20af472 137 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 9 134 23.837 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A3L04_04350 5958ff97369878dfbe83a584f20af472 137 ProSitePatterns PS00054 Ribosomal protein S11 signature. 102 124 - T 23-10-2018 IPR018102 Ribosomal S11, conserved site A3L04_08315 432c4974944e862705585081d36049e6 250 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 248 9.5E-61 T 23-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A3L04_08315 432c4974944e862705585081d36049e6 250 Gene3D G3DSA:3.40.1390.30 6 238 9.5E-77 T 23-10-2018 A3L04_08315 432c4974944e862705585081d36049e6 250 Gene3D G3DSA:3.40.1390.30 96 221 9.5E-77 T 23-10-2018 A3L04_08315 432c4974944e862705585081d36049e6 250 SUPERFAMILY SSF102705 1 249 3.79E-69 T 23-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily A3L04_08315 432c4974944e862705585081d36049e6 250 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 5 238 1.3E-59 T 23-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A3L04_07755 af61560659afb46cd864be4010d6dacc 305 Gene3D G3DSA:1.10.1040.10 171 295 5.7E-39 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A3L04_07755 af61560659afb46cd864be4010d6dacc 305 Gene3D G3DSA:3.40.50.720 1 170 4.3E-53 T 23-10-2018 A3L04_07755 af61560659afb46cd864be4010d6dacc 305 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 171 294 3.5E-30 T 23-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain A3L04_07755 af61560659afb46cd864be4010d6dacc 305 SUPERFAMILY SSF51735 2 149 1.94E-16 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_07755 af61560659afb46cd864be4010d6dacc 305 SUPERFAMILY SSF48179 171 294 1.39E-29 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A3L04_07755 af61560659afb46cd864be4010d6dacc 305 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 145 1.9E-33 T 23-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain A3L04_07755 af61560659afb46cd864be4010d6dacc 305 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 295 1.2E-82 T 23-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 A3L04_06605 2dce41dbcd266a5b02b80aed1bc46920 236 PIRSF PIRSF015736 1 236 4.0E-87 T 23-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase A3L04_06605 2dce41dbcd266a5b02b80aed1bc46920 236 Gene3D G3DSA:3.40.50.12500 6 236 3.8E-86 T 23-10-2018 A3L04_06605 2dce41dbcd266a5b02b80aed1bc46920 236 Pfam PF01177 Asp/Glu/Hydantoin racemase 11 217 4.5E-15 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L04_00070 7ea92b4305b1fd33a54b487ec0cdea93 237 Pfam PF00005 ABC transporter 20 160 2.5E-34 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_00070 7ea92b4305b1fd33a54b487ec0cdea93 237 Gene3D G3DSA:3.40.50.300 1 236 2.2E-72 T 23-10-2018 A3L04_00070 7ea92b4305b1fd33a54b487ec0cdea93 237 SUPERFAMILY SSF52540 3 222 3.06E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_00070 7ea92b4305b1fd33a54b487ec0cdea93 237 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_00070 7ea92b4305b1fd33a54b487ec0cdea93 237 SMART SM00382 28 217 7.8E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_10585 62e28ee226949b01e4055c1f3d628974 321 Gene3D G3DSA:3.40.50.150 142 314 2.3E-26 T 23-10-2018 A3L04_10585 62e28ee226949b01e4055c1f3d628974 321 Pfam PF13847 Methyltransferase domain 161 266 3.1E-14 T 23-10-2018 IPR025714 Methyltransferase domain A3L04_10585 62e28ee226949b01e4055c1f3d628974 321 SUPERFAMILY SSF53335 137 306 3.87E-28 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_04590 dc55f9ade89cc37de5e26ff73058a97a 264 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 34 263 2.0E-88 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A3L04_04590 dc55f9ade89cc37de5e26ff73058a97a 264 SUPERFAMILY SSF64005 31 259 8.76E-89 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 A3L04_04590 dc55f9ade89cc37de5e26ff73058a97a 264 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 209 226 - T 23-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 A3L04_04590 dc55f9ade89cc37de5e26ff73058a97a 264 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 34 264 40.519 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A3L04_04590 dc55f9ade89cc37de5e26ff73058a97a 264 Gene3D G3DSA:3.40.1180.10 18 264 5.0E-103 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 A3L04_04590 dc55f9ade89cc37de5e26ff73058a97a 264 Pfam PF01255 Putative undecaprenyl diphosphate synthase 41 263 6.5E-84 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A3L04_04375 1843eecbaba09d1c7f06b0d100438cc5 135 TIGRFAM TIGR03627 uS9_arch: ribosomal protein uS9 3 135 6.9E-62 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_04375 1843eecbaba09d1c7f06b0d100438cc5 135 SUPERFAMILY SSF54211 3 135 9.1E-35 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L04_04375 1843eecbaba09d1c7f06b0d100438cc5 135 Gene3D G3DSA:3.30.230.10 1 135 8.2E-52 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L04_04375 1843eecbaba09d1c7f06b0d100438cc5 135 ProSitePatterns PS00360 Ribosomal protein S9 signature. 68 86 - T 23-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 A3L04_04375 1843eecbaba09d1c7f06b0d100438cc5 135 Hamap MF_00532_A 30S ribosomal protein S9 [rpsI]. 3 135 37.753 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_04375 1843eecbaba09d1c7f06b0d100438cc5 135 Pfam PF00380 Ribosomal protein S9/S16 8 135 2.2E-30 T 23-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 A3L04_05555 6e6e1b2962093c3eed4e78dc7eeaa32e 112 SUPERFAMILY SSF46950 8 111 1.83E-28 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 A3L04_05555 6e6e1b2962093c3eed4e78dc7eeaa32e 112 PIRSF PIRSF015730 1 112 7.0E-37 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 A3L04_05555 6e6e1b2962093c3eed4e78dc7eeaa32e 112 Hamap MF_00026 DNA-binding protein . 3 112 16.469 T 23-10-2018 IPR022889 DNA-binding protein, archaeal A3L04_05555 6e6e1b2962093c3eed4e78dc7eeaa32e 112 Gene3D G3DSA:1.10.8.140 31 112 1.7E-25 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 A3L04_05555 6e6e1b2962093c3eed4e78dc7eeaa32e 112 Pfam PF01984 Double-stranded DNA-binding domain 8 110 4.2E-27 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 A3L04_01605 1d00dcbc93b736c9bd97a27a0727ca4e 248 SUPERFAMILY SSF52540 4 243 4.68E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01605 1d00dcbc93b736c9bd97a27a0727ca4e 248 SMART SM00382 26 206 3.3E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_01605 1d00dcbc93b736c9bd97a27a0727ca4e 248 Gene3D G3DSA:3.40.50.300 2 248 5.7E-78 T 23-10-2018 A3L04_01605 1d00dcbc93b736c9bd97a27a0727ca4e 248 Pfam PF06745 KaiC 9 245 1.4E-84 T 23-10-2018 IPR014774 KaiC-like domain A3L04_09780 8cb085c66974a41ba5bc3b78adc6089a 182 TIGRFAM TIGR00373 TIGR00373: transcription factor E 9 164 9.4E-52 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 A3L04_09780 8cb085c66974a41ba5bc3b78adc6089a 182 SUPERFAMILY SSF46785 3 86 1.05E-24 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_09780 8cb085c66974a41ba5bc3b78adc6089a 182 SMART SM00531 18 157 2.6E-68 T 23-10-2018 IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal GO:0006367 Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L04_09780 8cb085c66974a41ba5bc3b78adc6089a 182 PIRSF PIRSF006373 1 178 2.0E-73 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 A3L04_09780 8cb085c66974a41ba5bc3b78adc6089a 182 Pfam PF02002 TFIIE alpha subunit 7 110 4.0E-29 T 23-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L04_09780 8cb085c66974a41ba5bc3b78adc6089a 182 Gene3D G3DSA:1.10.10.10 1 86 4.1E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_09780 8cb085c66974a41ba5bc3b78adc6089a 182 Hamap MF_01909 Transcription factor E [tfe]. 2 165 26.818 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 A3L04_00740 14a8d801565fc57324aa256871979293 121 SUPERFAMILY SSF88723 2 120 9.81E-21 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_00740 14a8d801565fc57324aa256871979293 121 Pfam PF01850 PIN domain 3 116 3.5E-19 T 23-10-2018 IPR002716 PIN domain A3L04_00740 14a8d801565fc57324aa256871979293 121 Gene3D G3DSA:3.40.50.1010 2 120 9.1E-16 T 23-10-2018 A3L04_01780 d22296530a8f9a4ccc00e6a3ce1db565 523 Pfam PF01921 tRNA synthetases class I (K) 3 359 8.5E-131 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A3L04_01780 d22296530a8f9a4ccc00e6a3ce1db565 523 SUPERFAMILY SSF48163 322 520 1.2E-48 T 23-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A3L04_01780 d22296530a8f9a4ccc00e6a3ce1db565 523 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 2 520 3.8E-157 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A3L04_01780 d22296530a8f9a4ccc00e6a3ce1db565 523 Gene3D G3DSA:3.40.50.620 4 269 3.0E-113 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_01780 d22296530a8f9a4ccc00e6a3ce1db565 523 SUPERFAMILY SSF52374 3 318 6.7E-70 T 23-10-2018 A3L04_01780 d22296530a8f9a4ccc00e6a3ce1db565 523 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 2 523 37.083 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A3L04_01780 d22296530a8f9a4ccc00e6a3ce1db565 523 Gene3D G3DSA:2.30.30.300 170 212 3.0E-113 T 23-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 A3L04_01780 d22296530a8f9a4ccc00e6a3ce1db565 523 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 30 39 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_01780 d22296530a8f9a4ccc00e6a3ce1db565 523 Gene3D G3DSA:1.10.10.770 318 430 1.3E-38 T 23-10-2018 A3L04_01780 d22296530a8f9a4ccc00e6a3ce1db565 523 Gene3D G3DSA:1.10.10.860 270 317 1.2E-24 T 23-10-2018 A3L04_01780 d22296530a8f9a4ccc00e6a3ce1db565 523 Gene3D G3DSA:1.10.10.350 431 523 4.3E-24 T 23-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A3L04_03980 0d95112d8b8b1298755e29402adbaea0 411 TIGRFAM TIGR03680 eif2g_arch: translation initiation factor 2, gamma subunit 8 410 8.4E-213 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit A3L04_03980 0d95112d8b8b1298755e29402adbaea0 411 Pfam PF09173 Initiation factor eIF2 gamma, C terminal 325 409 1.6E-31 T 23-10-2018 IPR015256 Translation initiation factor 2, gamma subunit, C-terminal A3L04_03980 0d95112d8b8b1298755e29402adbaea0 411 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 196 2.2E-16 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L04_03980 0d95112d8b8b1298755e29402adbaea0 411 PRINTS PR00315 GTP-binding elongation factor signature 103 114 2.2E-13 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_03980 0d95112d8b8b1298755e29402adbaea0 411 PRINTS PR00315 GTP-binding elongation factor signature 13 26 2.2E-13 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_03980 0d95112d8b8b1298755e29402adbaea0 411 PRINTS PR00315 GTP-binding elongation factor signature 141 150 2.2E-13 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_03980 0d95112d8b8b1298755e29402adbaea0 411 PRINTS PR00315 GTP-binding elongation factor signature 87 97 2.2E-13 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_03980 0d95112d8b8b1298755e29402adbaea0 411 Gene3D G3DSA:2.40.30.10 205 319 9.4E-47 T 23-10-2018 A3L04_03980 0d95112d8b8b1298755e29402adbaea0 411 SUPERFAMILY SSF50465 318 410 5.04E-33 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A3L04_03980 0d95112d8b8b1298755e29402adbaea0 411 Gene3D G3DSA:3.40.50.300 2 204 2.1E-68 T 23-10-2018 A3L04_03980 0d95112d8b8b1298755e29402adbaea0 411 Pfam PF03144 Elongation factor Tu domain 2 232 312 9.7E-11 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A3L04_03980 0d95112d8b8b1298755e29402adbaea0 411 SUPERFAMILY SSF52540 9 200 2.52E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_03980 0d95112d8b8b1298755e29402adbaea0 411 Gene3D G3DSA:2.40.30.10 320 411 7.0E-35 T 23-10-2018 A3L04_03980 0d95112d8b8b1298755e29402adbaea0 411 Hamap MF_00119 Translation initiation factor 2 subunit gamma [eif2g]. 4 410 64.632 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit A3L04_03980 0d95112d8b8b1298755e29402adbaea0 411 SUPERFAMILY SSF50447 204 317 1.08E-38 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L04_03980 0d95112d8b8b1298755e29402adbaea0 411 Pfam PF00009 Elongation factor Tu GTP binding domain 12 200 2.1E-30 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L04_02355 7b897876f74a6e3d2dff0f2ee0376a2d 50 Hamap MF_00777 30S ribosomal protein S27ae [rps27ae]. 4 49 19.519 T 23-10-2018 IPR022845 Ribosomal protein S27ae A3L04_02355 7b897876f74a6e3d2dff0f2ee0376a2d 50 Pfam PF01599 Ribosomal protein S27a 5 46 1.2E-21 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L04_02355 7b897876f74a6e3d2dff0f2ee0376a2d 50 SUPERFAMILY SSF57829 4 50 1.37E-20 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L04_02355 7b897876f74a6e3d2dff0f2ee0376a2d 50 SMART SM01402 4 46 1.5E-23 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L04_02355 7b897876f74a6e3d2dff0f2ee0376a2d 50 Gene3D G3DSA:2.20.25.660 2 49 9.9E-19 T 23-10-2018 IPR038582 S27a-like superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L04_01020 c9d9b4365b49d796b7d99402da014d25 384 TIGRFAM TIGR01899 cas_TM1807_csm5: CRISPR type III-A/MTUBE-associated RAMP protein Csm5 2 384 3.4E-88 T 23-10-2018 IPR010173 CRISPR-associated protein, TM1807 A3L04_01020 c9d9b4365b49d796b7d99402da014d25 384 Pfam PF03787 RAMP superfamily 3 331 4.8E-22 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein A3L04_07270 f99b0965adf267508eedd7b8e624c6c5 139 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 12 96 3.0E-39 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A3L04_07270 f99b0965adf267508eedd7b8e624c6c5 139 SUPERFAMILY SSF75471 6 101 5.49E-17 T 23-10-2018 IPR035920 YhbY-like superfamily A3L04_07270 f99b0965adf267508eedd7b8e624c6c5 139 SMART SM01103 6 93 5.0E-24 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A3L04_07270 f99b0965adf267508eedd7b8e624c6c5 139 Pfam PF01985 CRS1 / YhbY (CRM) domain 6 93 2.5E-12 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A3L04_07270 f99b0965adf267508eedd7b8e624c6c5 139 Gene3D G3DSA:3.30.110.60 6 114 4.2E-20 T 23-10-2018 IPR035920 YhbY-like superfamily A3L04_06880 7a13646cdf9c90663d826c02c05d5e4b 411 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 20 403 4.5E-63 T 23-10-2018 A3L04_06880 7a13646cdf9c90663d826c02c05d5e4b 411 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 342 372 - T 23-10-2018 IPR030390 RNA methyltransferase TrmA, active site A3L04_06880 7a13646cdf9c90663d826c02c05d5e4b 411 Gene3D G3DSA:3.40.1350.30 107 253 8.4E-93 T 23-10-2018 A3L04_06880 7a13646cdf9c90663d826c02c05d5e4b 411 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 393 403 - T 23-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site A3L04_06880 7a13646cdf9c90663d826c02c05d5e4b 411 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 244 320 1.6E-6 T 23-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A3L04_06880 7a13646cdf9c90663d826c02c05d5e4b 411 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 336 409 4.7E-12 T 23-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A3L04_06880 7a13646cdf9c90663d826c02c05d5e4b 411 Gene3D G3DSA:3.40.50.150 68 405 8.4E-93 T 23-10-2018 A3L04_06880 7a13646cdf9c90663d826c02c05d5e4b 411 Gene3D G3DSA:2.40.50.140 1 56 1.2E-17 T 23-10-2018 A3L04_06880 7a13646cdf9c90663d826c02c05d5e4b 411 SUPERFAMILY SSF53335 55 409 3.58E-59 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_04705 2acbe9a9bc2fcea40e9646d6945f9267 382 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 143 158 2.7E-30 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L04_04705 2acbe9a9bc2fcea40e9646d6945f9267 382 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 222 243 2.7E-30 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L04_04705 2acbe9a9bc2fcea40e9646d6945f9267 382 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 198 215 2.7E-30 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L04_04705 2acbe9a9bc2fcea40e9646d6945f9267 382 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 103 114 2.7E-30 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L04_04705 2acbe9a9bc2fcea40e9646d6945f9267 382 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 125 142 2.7E-30 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L04_04705 2acbe9a9bc2fcea40e9646d6945f9267 382 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 254 270 2.7E-30 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L04_04705 2acbe9a9bc2fcea40e9646d6945f9267 382 Gene3D G3DSA:3.40.1360.10 152 381 2.4E-67 T 23-10-2018 A3L04_04705 2acbe9a9bc2fcea40e9646d6945f9267 382 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 45 65 1.2E-50 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L04_04705 2acbe9a9bc2fcea40e9646d6945f9267 382 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 119 136 1.2E-50 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L04_04705 2acbe9a9bc2fcea40e9646d6945f9267 382 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 172 190 1.2E-50 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L04_04705 2acbe9a9bc2fcea40e9646d6945f9267 382 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 352 375 1.2E-50 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L04_04705 2acbe9a9bc2fcea40e9646d6945f9267 382 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 228 248 1.2E-50 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L04_04705 2acbe9a9bc2fcea40e9646d6945f9267 382 Pfam PF04406 Type IIB DNA topoisomerase 79 148 2.4E-19 T 23-10-2018 IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal GO:0003677|GO:0003824|GO:0005524|GO:0005694|GO:0006259 Reactome: R-HSA-912446 A3L04_04705 2acbe9a9bc2fcea40e9646d6945f9267 382 Hamap MF_00132 Type 2 DNA topoisomerase 6 subunit A [top6A]. 13 381 41.257 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L04_04705 2acbe9a9bc2fcea40e9646d6945f9267 382 Gene3D G3DSA:1.10.10.10 9 151 5.2E-52 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_04705 2acbe9a9bc2fcea40e9646d6945f9267 382 SUPERFAMILY SSF56726 77 379 1.31E-81 T 23-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L04_01105 655aaf8385ae4a41b91261f3df26edff 285 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 22 113 1.8E-9 T 23-10-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain A3L04_01105 655aaf8385ae4a41b91261f3df26edff 285 Gene3D G3DSA:3.90.1570.30 7 127 1.5E-9 T 23-10-2018 A3L04_08215 5eab43b664f9b8be6eb9a4080d7dc75b 117 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 115 4.9E-17 T 23-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 A3L04_08215 5eab43b664f9b8be6eb9a4080d7dc75b 117 SUPERFAMILY SSF50118 3 116 1.4E-19 T 23-10-2018 A3L04_08215 5eab43b664f9b8be6eb9a4080d7dc75b 117 Gene3D G3DSA:2.30.30.110 17 117 1.6E-17 T 23-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A3L04_09860 41c4010d59157e81887c1d229bfe2087 816 Pfam PF13718 GNAT acetyltransferase 2 498 615 4.7E-32 T 23-10-2018 IPR000182 GNAT domain A3L04_09860 41c4010d59157e81887c1d229bfe2087 816 Pfam PF05127 Helicase 283 457 1.2E-56 T 23-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 A3L04_09860 41c4010d59157e81887c1d229bfe2087 816 Gene3D G3DSA:3.40.630.30 455 661 3.2E-55 T 23-10-2018 A3L04_09860 41c4010d59157e81887c1d229bfe2087 816 Gene3D G3DSA:3.40.50.12320 279 447 3.7E-35 T 23-10-2018 A3L04_09860 41c4010d59157e81887c1d229bfe2087 816 Gene3D G3DSA:3.40.50.11040 95 247 2.2E-10 T 23-10-2018 A3L04_09860 41c4010d59157e81887c1d229bfe2087 816 Pfam PF08351 Domain of unknown function (DUF1726) 127 219 2.1E-33 T 23-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 A3L04_09860 41c4010d59157e81887c1d229bfe2087 816 SUPERFAMILY SSF52540 208 396 2.47E-9 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09860 41c4010d59157e81887c1d229bfe2087 816 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 39 806 50.233 T 23-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 A3L04_09860 41c4010d59157e81887c1d229bfe2087 816 SUPERFAMILY SSF55729 489 646 8.54E-10 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L04_06680 985ba4169c1dd858233c5be3e59fe552 157 Gene3D G3DSA:2.60.40.1820 22 156 5.7E-6 T 23-10-2018 A3L04_06680 985ba4169c1dd858233c5be3e59fe552 157 SUPERFAMILY SSF117070 30 153 4.32E-12 T 23-10-2018 A3L04_06835 dc98380b0ac5b780ab901d0da0df1f16 90 PRINTS PR01250 Ribosomal protein L34 signature 56 78 3.7E-16 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_06835 dc98380b0ac5b780ab901d0da0df1f16 90 PRINTS PR01250 Ribosomal protein L34 signature 18 35 3.7E-16 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_06835 dc98380b0ac5b780ab901d0da0df1f16 90 PRINTS PR01250 Ribosomal protein L34 signature 5 18 3.7E-16 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_06835 dc98380b0ac5b780ab901d0da0df1f16 90 PRINTS PR01250 Ribosomal protein L34 signature 36 46 3.7E-16 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_06835 dc98380b0ac5b780ab901d0da0df1f16 90 Gene3D G3DSA:3.40.1800.40 29 87 4.5E-8 T 23-10-2018 IPR038562 Ribosomal protein L34Ae superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_06835 dc98380b0ac5b780ab901d0da0df1f16 90 ProSitePatterns PS01145 Ribosomal protein L34e signature. 7 20 - T 23-10-2018 IPR018065 Ribosomal protein L34e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_06835 dc98380b0ac5b780ab901d0da0df1f16 90 Hamap MF_00349 50S ribosomal protein L34e [rpl34e]. 1 86 29.2 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_06835 dc98380b0ac5b780ab901d0da0df1f16 90 Pfam PF01199 Ribosomal protein L34e 3 83 1.2E-22 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_00265 ebd436119deabbe4ee9a2da3ebd3e286 49 SMART SM00659 4 49 2.8E-21 T 23-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L04_00265 ebd436119deabbe4ee9a2da3ebd3e286 49 SUPERFAMILY SSF63393 3 48 1.62E-12 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A3L04_00265 ebd436119deabbe4ee9a2da3ebd3e286 49 Gene3D G3DSA:2.20.28.30 1 49 1.4E-21 T 23-10-2018 A3L04_00265 ebd436119deabbe4ee9a2da3ebd3e286 49 Pfam PF03604 DNA directed RNA polymerase, 7 kDa subunit 6 39 1.8E-9 T 23-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L04_00265 ebd436119deabbe4ee9a2da3ebd3e286 49 Hamap MF_00615 DNA-directed RNA polymerase subunit P [rpoP]. 6 49 16.653 T 23-10-2018 IPR023464 DNA-directed RNA polymerase subunit P (Rpo12) GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_05400 6aefecc1e14a6592dacca2c3a628bfdc 185 Hamap MF_01111 UPF0200 protein . 2 182 33.935 T 23-10-2018 IPR022970 Nucleoside triphosphate hydrolase-related A3L04_05400 6aefecc1e14a6592dacca2c3a628bfdc 185 Gene3D G3DSA:3.40.50.300 1 183 8.5E-48 T 23-10-2018 A3L04_05400 6aefecc1e14a6592dacca2c3a628bfdc 185 Pfam PF13207 AAA domain 6 137 2.5E-17 T 23-10-2018 A3L04_05400 6aefecc1e14a6592dacca2c3a628bfdc 185 SUPERFAMILY SSF52540 1 183 1.65E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_03540 0658be01c9cf59834bc6ef459bba1ae6 164 SUPERFAMILY SSF56300 1 161 2.06E-37 T 23-10-2018 A3L04_03540 0658be01c9cf59834bc6ef459bba1ae6 164 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 150 6.7E-29 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L04_03540 0658be01c9cf59834bc6ef459bba1ae6 164 Gene3D G3DSA:3.60.21.10 1 163 4.4E-44 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L04_03540 0658be01c9cf59834bc6ef459bba1ae6 164 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 156 2.1E-35 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A3L04_03475 90ab26e7ccae36e338478851a53a14d0 203 Gene3D G3DSA:3.30.420.100 1 197 2.5E-71 T 23-10-2018 A3L04_03475 90ab26e7ccae36e338478851a53a14d0 203 SUPERFAMILY SSF53137 2 193 5.23E-63 T 23-10-2018 A3L04_03475 90ab26e7ccae36e338478851a53a14d0 203 Hamap MF_01337_A 50S ribosomal protein L18 [rplR]. 5 192 45.517 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03475 90ab26e7ccae36e338478851a53a14d0 203 PRINTS PR00058 Ribosomal protein L5 signature 1 12 2.6E-9 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03475 90ab26e7ccae36e338478851a53a14d0 203 PRINTS PR00058 Ribosomal protein L5 signature 103 122 2.6E-9 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03475 90ab26e7ccae36e338478851a53a14d0 203 PRINTS PR00058 Ribosomal protein L5 signature 123 142 2.6E-9 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03475 90ab26e7ccae36e338478851a53a14d0 203 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 6 94 1.5E-14 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03475 90ab26e7ccae36e338478851a53a14d0 203 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 100 134 9.6E-8 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03475 90ab26e7ccae36e338478851a53a14d0 203 Pfam PF14204 Ribosomal L18 C-terminal region 143 192 1.3E-11 T 23-10-2018 IPR025607 Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_09445 7798cacfa895e65838e5019bb9ed279b 805 SUPERFAMILY SSF49384 46 119 7.85E-6 T 23-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 A3L04_09445 7798cacfa895e65838e5019bb9ed279b 805 SMART SM00637 187 270 1.5E-4 T 23-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A3L04_09445 7798cacfa895e65838e5019bb9ed279b 805 SMART SM00637 38 129 0.001 T 23-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A3L04_09445 7798cacfa895e65838e5019bb9ed279b 805 Gene3D G3DSA:2.60.40.290 181 280 6.6E-34 T 23-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 A3L04_09445 7798cacfa895e65838e5019bb9ed279b 805 Gene3D G3DSA:2.60.40.290 34 133 3.1E-25 T 23-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 A3L04_09445 7798cacfa895e65838e5019bb9ed279b 805 SUPERFAMILY SSF49384 185 266 9.77E-9 T 23-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 A3L04_01185 414d4d759fa119ef84ac31b36088fe20 337 Pfam PF01901 Putative O-antigen polymerase 4 304 2.7E-53 T 23-10-2018 IPR002760 Putative O-antigen polymerase A3L04_02555 0dfb66f9513d5f9759c7df7e3b588b14 275 PIRSF PIRSF006519 22 274 3.6E-89 T 23-10-2018 IPR012061 Glutamate synthase, large subunit domain 3 stand-alone protein A3L04_02555 0dfb66f9513d5f9759c7df7e3b588b14 275 Pfam PF01493 GXGXG motif 55 218 4.6E-36 T 23-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 A3L04_02555 0dfb66f9513d5f9759c7df7e3b588b14 275 Gene3D G3DSA:2.160.20.60 31 270 3.5E-34 T 23-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 A3L04_02555 0dfb66f9513d5f9759c7df7e3b588b14 275 SUPERFAMILY SSF69336 32 270 2.22E-52 T 23-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 A3L04_07255 4e18d7a3bade5a4e68cc2f0bcc02a42f 200 Pfam PF04289 Protein of unknown function (DUF447) 13 185 8.3E-29 T 23-10-2018 IPR007386 Protein of unknown function DUF447 A3L04_07255 4e18d7a3bade5a4e68cc2f0bcc02a42f 200 Gene3D G3DSA:1.20.58.290 60 184 4.1E-14 T 23-10-2018 A3L04_07255 4e18d7a3bade5a4e68cc2f0bcc02a42f 200 SUPERFAMILY SSF50475 5 190 3.27E-29 T 23-10-2018 A3L04_07255 4e18d7a3bade5a4e68cc2f0bcc02a42f 200 Gene3D G3DSA:2.30.110.10 19 132 4.1E-14 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A3L04_07255 4e18d7a3bade5a4e68cc2f0bcc02a42f 200 PIRSF PIRSF018747 1 196 2.4E-70 T 23-10-2018 IPR016733 Uncharacterised conserved protein UCP018747 A3L04_02015 723bf3b21f45be56216cc7ff1cd73b8a 370 Gene3D G3DSA:1.20.1690.10 112 219 6.1E-54 T 23-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L04_02015 723bf3b21f45be56216cc7ff1cd73b8a 370 Pfam PF01992 ATP synthase (C/AC39) subunit 39 364 1.0E-67 T 23-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L04_02015 723bf3b21f45be56216cc7ff1cd73b8a 370 Gene3D G3DSA:1.20.1690.10 220 327 6.1E-54 T 23-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L04_02015 723bf3b21f45be56216cc7ff1cd73b8a 370 Hamap MF_00314 V-type ATP synthase subunit C [atpC]. 31 367 24.259 T 23-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 A3L04_02015 723bf3b21f45be56216cc7ff1cd73b8a 370 TIGRFAM TIGR02923 AhaC: ATP synthase A1, C subunit 32 366 5.9E-87 T 23-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 A3L04_02015 723bf3b21f45be56216cc7ff1cd73b8a 370 Gene3D G3DSA:1.10.132.50 35 357 6.1E-54 T 23-10-2018 A3L04_02015 723bf3b21f45be56216cc7ff1cd73b8a 370 SUPERFAMILY SSF103486 35 367 5.49E-80 T 23-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L04_02795 cc5ce2a4565acb25b6d806e8889bef81 335 TIGRFAM TIGR01898 cas_TM1791_cmr6: CRISPR type III-B/RAMP module RAMP protein Cmr6 92 328 3.4E-59 T 23-10-2018 IPR010172 CRISPR-associated protein, TM1791 A3L04_02795 cc5ce2a4565acb25b6d806e8889bef81 335 Pfam PF03787 RAMP superfamily 94 328 3.3E-10 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein A3L04_03400 7d58499c52ee500f258f7e4c6c2036b2 155 Hamap MF_01331_A 50S ribosomal protein L22 [rplV]. 3 153 33.832 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03400 7d58499c52ee500f258f7e4c6c2036b2 155 Gene3D G3DSA:3.90.470.10 5 155 7.0E-54 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 A3L04_03400 7d58499c52ee500f258f7e4c6c2036b2 155 SUPERFAMILY SSF54843 7 152 2.62E-48 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 A3L04_03400 7d58499c52ee500f258f7e4c6c2036b2 155 Pfam PF00237 Ribosomal protein L22p/L17e 20 150 2.4E-34 T 23-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 A3L04_03400 7d58499c52ee500f258f7e4c6c2036b2 155 TIGRFAM TIGR01038 uL22_arch_euk: ribosomal protein uL22 7 152 4.5E-69 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03400 7d58499c52ee500f258f7e4c6c2036b2 155 ProSitePatterns PS00464 Ribosomal protein L22 signature. 126 150 - T 23-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_05800 27f551944bcedee9e6ce952140c335ca 164 Hamap MF_01032 Methanogen homoaconitase small subunit [hacB]. 3 163 43.223 T 23-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 A3L04_05800 27f551944bcedee9e6ce952140c335ca 164 TIGRFAM TIGR02084 leud: 3-isopropylmalate dehydratase, small subunit 5 159 2.1E-81 T 23-10-2018 IPR011824 Hydrolyase LeuD/DmdB, bacterial GO:0016836 KEGG: 00290+4.2.1.33 A3L04_05800 27f551944bcedee9e6ce952140c335ca 164 SUPERFAMILY SSF52016 3 162 2.16E-56 T 23-10-2018 A3L04_05800 27f551944bcedee9e6ce952140c335ca 164 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 5 161 3.3E-70 T 23-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 A3L04_05800 27f551944bcedee9e6ce952140c335ca 164 Pfam PF00694 Aconitase C-terminal domain 38 104 2.1E-22 T 23-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 A3L04_05800 27f551944bcedee9e6ce952140c335ca 164 Gene3D G3DSA:3.20.19.10 1 164 2.0E-65 T 23-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 A3L04_00940 0f8eb3ef5700b3acecbff94c07c6fc26 301 Pfam PF03477 ATP cone domain 8 86 2.6E-8 T 23-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A3L04_00940 0f8eb3ef5700b3acecbff94c07c6fc26 301 Gene3D G3DSA:3.40.50.300 91 262 3.1E-11 T 23-10-2018 A3L04_00940 0f8eb3ef5700b3acecbff94c07c6fc26 301 SUPERFAMILY SSF52540 92 282 7.71E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_00940 0f8eb3ef5700b3acecbff94c07c6fc26 301 Hamap MF_00769 2-phosphoglycerate kinase [pgk2]. 2 294 45.823 T 23-10-2018 IPR020872 2-phosphoglycerate kinase GO:0016774 A3L04_05760 3200bb680949b5aa74d0648716059178 161 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 118 126 - T 23-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L04_05760 3200bb680949b5aa74d0648716059178 161 Gene3D G3DSA:3.30.70.141 1 157 2.9E-71 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L04_05760 3200bb680949b5aa74d0648716059178 161 Pfam PF00334 Nucleoside diphosphate kinase 5 141 5.4E-59 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L04_05760 3200bb680949b5aa74d0648716059178 161 SUPERFAMILY SSF54919 4 151 3.67E-61 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L04_05760 3200bb680949b5aa74d0648716059178 161 PRINTS PR01243 Nucleoside diphosphate kinase signature 51 70 1.9E-45 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L04_05760 3200bb680949b5aa74d0648716059178 161 PRINTS PR01243 Nucleoside diphosphate kinase signature 71 88 1.9E-45 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L04_05760 3200bb680949b5aa74d0648716059178 161 PRINTS PR01243 Nucleoside diphosphate kinase signature 92 108 1.9E-45 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L04_05760 3200bb680949b5aa74d0648716059178 161 PRINTS PR01243 Nucleoside diphosphate kinase signature 7 29 1.9E-45 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L04_05760 3200bb680949b5aa74d0648716059178 161 PRINTS PR01243 Nucleoside diphosphate kinase signature 118 137 1.9E-45 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L04_05760 3200bb680949b5aa74d0648716059178 161 SMART SM00562 4 144 1.4E-83 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L04_05760 3200bb680949b5aa74d0648716059178 161 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 4 142 36.551 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L04_10820 c4bca925d9e5ae47ca32b68f1491ec86 781 Gene3D G3DSA:3.40.50.880 438 654 4.0E-16 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L04_10820 c4bca925d9e5ae47ca32b68f1491ec86 781 SUPERFAMILY SSF51445 3 421 6.11E-62 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L04_10820 c4bca925d9e5ae47ca32b68f1491ec86 781 Pfam PF08532 Beta-galactosidase trimerisation domain 482 647 1.5E-5 T 23-10-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A3L04_10820 c4bca925d9e5ae47ca32b68f1491ec86 781 PRINTS PR00742 Glycosyl hydrolase family 35 signature 93 112 3.7E-7 T 23-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A3L04_10820 c4bca925d9e5ae47ca32b68f1491ec86 781 PRINTS PR00742 Glycosyl hydrolase family 35 signature 13 30 3.7E-7 T 23-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A3L04_10820 c4bca925d9e5ae47ca32b68f1491ec86 781 Pfam PF02449 Beta-galactosidase 24 418 5.3E-83 T 23-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A3L04_10820 c4bca925d9e5ae47ca32b68f1491ec86 781 SUPERFAMILY SSF52317 473 629 2.9E-8 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L04_01630 cbb8aab8a87c3884b69b115f5d9381b0 187 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 7 177 1.9E-47 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal A3L04_01630 cbb8aab8a87c3884b69b115f5d9381b0 187 SMART SM01007 6 179 9.4E-54 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal A3L04_01630 cbb8aab8a87c3884b69b115f5d9381b0 187 Gene3D G3DSA:3.40.225.10 1 187 1.6E-57 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L04_01630 cbb8aab8a87c3884b69b115f5d9381b0 187 SUPERFAMILY SSF53639 3 180 1.81E-54 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L04_03470 451105646e2f08feac103fc36520099e 150 Gene3D G3DSA:1.10.1650.10 1 56 2.0E-26 T 23-10-2018 IPR015972 Ribosomal protein L19/L19e, domain 1 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03470 451105646e2f08feac103fc36520099e 150 Gene3D G3DSA:1.10.1200.240 58 148 2.3E-30 T 23-10-2018 A3L04_03470 451105646e2f08feac103fc36520099e 150 Hamap MF_01475 50S ribosomal protein L19e [rpl19e]. 3 149 26.996 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03470 451105646e2f08feac103fc36520099e 150 SUPERFAMILY SSF48140 4 142 1.31E-57 T 23-10-2018 IPR035970 Ribosomal protein L19/L19e superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03470 451105646e2f08feac103fc36520099e 150 SMART SM01416 3 146 1.4E-88 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03470 451105646e2f08feac103fc36520099e 150 ProSitePatterns PS00526 Ribosomal protein L19e signature. 7 26 - T 23-10-2018 IPR023638 Ribosomal protein L19/L19e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03470 451105646e2f08feac103fc36520099e 150 Pfam PF01280 Ribosomal protein L19e 4 144 5.9E-59 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_00590 0c9440a99a2a9a1a8fd3826f78100ba3 616 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 217 597 1.7E-95 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L04_00590 0c9440a99a2a9a1a8fd3826f78100ba3 616 Gene3D G3DSA:1.10.599.10 235 597 5.2E-90 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A3L04_00590 0c9440a99a2a9a1a8fd3826f78100ba3 616 SMART SM00790 4 204 2.1E-110 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L04_00590 0c9440a99a2a9a1a8fd3826f78100ba3 616 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 200 5.3E-69 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L04_00590 0c9440a99a2a9a1a8fd3826f78100ba3 616 SUPERFAMILY SSF48310 207 601 5.49E-104 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L04_00590 0c9440a99a2a9a1a8fd3826f78100ba3 616 SUPERFAMILY SSF56228 1 204 6.28E-66 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L04_00590 0c9440a99a2a9a1a8fd3826f78100ba3 616 Gene3D G3DSA:3.60.9.10 1 207 1.7E-74 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L04_00590 0c9440a99a2a9a1a8fd3826f78100ba3 616 Gene3D G3DSA:1.10.569.10 237 428 5.2E-90 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L04_01115 dbcfee73923f3ae868289e7a879e18c6 209 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 5 195 2.7E-39 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L04_01115 dbcfee73923f3ae868289e7a879e18c6 209 Gene3D G3DSA:3.40.50.11570 1 199 3.9E-48 T 23-10-2018 A3L04_01190 1fb66aae58db6fadb839f7754d0c4613 222 SUPERFAMILY SSF159071 39 103 1.44E-5 T 23-10-2018 A3L04_08400 aacbed06b3648a760c45d7b304a6972d 334 SMART SM00859 2 123 8.3E-32 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A3L04_08400 aacbed06b3648a760c45d7b304a6972d 334 SUPERFAMILY SSF55347 140 316 5.06E-38 T 23-10-2018 A3L04_08400 aacbed06b3648a760c45d7b304a6972d 334 Gene3D G3DSA:3.40.50.720 2 327 5.3E-123 T 23-10-2018 A3L04_08400 aacbed06b3648a760c45d7b304a6972d 334 SUPERFAMILY SSF51735 1 168 3.09E-40 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_08400 aacbed06b3648a760c45d7b304a6972d 334 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 121 4.8E-30 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A3L04_08400 aacbed06b3648a760c45d7b304a6972d 334 Gene3D G3DSA:3.30.360.10 142 311 5.3E-123 T 23-10-2018 A3L04_08400 aacbed06b3648a760c45d7b304a6972d 334 TIGRFAM TIGR00978 asd_EA: aspartate-semialdehyde dehydrogenase 1 330 7.2E-141 T 23-10-2018 IPR005676 Aspartate-semialdehyde dehydrogenase, peptidoglycan lacking GO:0050661|GO:0055114 A3L04_08400 aacbed06b3648a760c45d7b304a6972d 334 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 152 314 8.8E-32 T 23-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A3L04_08400 aacbed06b3648a760c45d7b304a6972d 334 PIRSF PIRSF000148 1 334 2.0E-93 T 23-10-2018 A3L04_08525 f58f060380434d0e2c8062b8fe494eed 1053 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 603 609 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A3L04_08525 f58f060380434d0e2c8062b8fe494eed 1053 Pfam PF06634 Protein of unknown function (DUF1156) 11 59 2.8E-11 T 23-10-2018 IPR009537 Domain of unknown function DUF1156 A3L04_08525 f58f060380434d0e2c8062b8fe494eed 1053 SUPERFAMILY SSF53335 80 731 3.2E-12 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_08525 f58f060380434d0e2c8062b8fe494eed 1053 Gene3D G3DSA:3.40.50.150 553 672 4.7E-7 T 23-10-2018 A3L04_08525 f58f060380434d0e2c8062b8fe494eed 1053 PIRSF PIRSF009427 1 1049 0.0 T 23-10-2018 IPR014455 DNA methylase, N-6 adenine-specific, MK1259 type A3L04_07000 311af6bb43c1e66480314acd89d17de6 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 233 249 3.6E-28 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_07000 311af6bb43c1e66480314acd89d17de6 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 291 308 3.6E-28 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_07000 311af6bb43c1e66480314acd89d17de6 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 88 102 3.6E-28 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_07000 311af6bb43c1e66480314acd89d17de6 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 117 127 3.6E-28 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_07000 311af6bb43c1e66480314acd89d17de6 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 183 195 3.6E-28 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L04_07000 311af6bb43c1e66480314acd89d17de6 309 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 42 308 1.2E-89 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L04_07000 311af6bb43c1e66480314acd89d17de6 309 SUPERFAMILY SSF53335 5 308 6.81E-76 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_07000 311af6bb43c1e66480314acd89d17de6 309 Pfam PF01189 16S rRNA methyltransferase RsmB/F 106 307 2.4E-58 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L04_07000 311af6bb43c1e66480314acd89d17de6 309 Gene3D G3DSA:3.40.50.150 103 309 1.9E-68 T 23-10-2018 A3L04_07000 311af6bb43c1e66480314acd89d17de6 309 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 12 102 6.8E-21 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L04_07000 311af6bb43c1e66480314acd89d17de6 309 Gene3D G3DSA:3.30.70.3130 1 101 1.1E-36 T 23-10-2018 A3L04_07000 311af6bb43c1e66480314acd89d17de6 309 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 182 193 - T 23-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 A3L04_06295 a647b9775b4c125139fae0bd100b6843 390 Pfam PF00999 Sodium/hydrogen exchanger family 9 382 8.4E-56 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L04_06295 a647b9775b4c125139fae0bd100b6843 390 Gene3D G3DSA:1.20.1530.20 1 390 1.5E-75 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L04_07470 eed04789b0f21fbfc90774cc5d2a1a82 587 Pfam PF13353 4Fe-4S single cluster domain 143 224 4.5E-6 T 23-10-2018 A3L04_07470 eed04789b0f21fbfc90774cc5d2a1a82 587 SUPERFAMILY SSF102114 128 394 5.89E-43 T 23-10-2018 A3L04_07470 eed04789b0f21fbfc90774cc5d2a1a82 587 Gene3D G3DSA:3.20.20.70 128 399 4.7E-34 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_07470 eed04789b0f21fbfc90774cc5d2a1a82 587 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 145 156 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L04_07470 eed04789b0f21fbfc90774cc5d2a1a82 587 Pfam PF04055 Radical SAM superfamily 143 302 3.6E-23 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_07240 7defa0e1952e0c6ec7310d58d04832c0 911 Pfam PF00271 Helicase conserved C-terminal domain 240 337 2.8E-19 T 23-10-2018 IPR001650 Helicase, C-terminal A3L04_07240 7defa0e1952e0c6ec7310d58d04832c0 911 Pfam PF00270 DEAD/DEAH box helicase 18 183 4.0E-27 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L04_07240 7defa0e1952e0c6ec7310d58d04832c0 911 Gene3D G3DSA:3.40.50.300 205 376 1.2E-28 T 23-10-2018 A3L04_07240 7defa0e1952e0c6ec7310d58d04832c0 911 SUPERFAMILY SSF52540 27 352 2.25E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_07240 7defa0e1952e0c6ec7310d58d04832c0 911 Gene3D G3DSA:3.40.50.300 2 201 2.5E-47 T 23-10-2018 A3L04_07240 7defa0e1952e0c6ec7310d58d04832c0 911 SMART SM00490 260 340 2.6E-22 T 23-10-2018 IPR001650 Helicase, C-terminal A3L04_07240 7defa0e1952e0c6ec7310d58d04832c0 911 SMART SM00487 12 211 3.6E-36 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L04_07240 7defa0e1952e0c6ec7310d58d04832c0 911 Pfam PF08494 DEAD/H associated 583 749 7.2E-17 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 A3L04_07240 7defa0e1952e0c6ec7310d58d04832c0 911 PIRSF PIRSF037307 1 911 0.0 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 A3L04_00375 51ac10f6dc175cec9f8812c70b22d411 157 SUPERFAMILY SSF51283 1 152 8.77E-42 T 23-10-2018 IPR036157 dUTPase-like superfamily A3L04_00375 51ac10f6dc175cec9f8812c70b22d411 157 Gene3D G3DSA:2.70.40.10 1 156 1.1E-44 T 23-10-2018 IPR036157 dUTPase-like superfamily A3L04_00375 51ac10f6dc175cec9f8812c70b22d411 157 Pfam PF00692 dUTPase 49 139 1.6E-13 T 23-10-2018 IPR029054 dUTPase-like A3L04_00375 51ac10f6dc175cec9f8812c70b22d411 157 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 9 152 4.2E-48 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 A3L04_00375 51ac10f6dc175cec9f8812c70b22d411 157 Hamap MF_00146 dCTP deaminase [dcd]. 1 153 28.471 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 A3L04_08310 87245e613630e7af10a0e350bc4bead6 391 Pfam PF00266 Aminotransferase class-V 20 381 5.5E-35 T 23-10-2018 IPR000192 Aminotransferase class V domain A3L04_08310 87245e613630e7af10a0e350bc4bead6 391 Gene3D G3DSA:3.90.1150.10 18 381 9.5E-71 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L04_08310 87245e613630e7af10a0e350bc4bead6 391 Gene3D G3DSA:3.40.640.10 30 298 9.5E-71 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L04_08310 87245e613630e7af10a0e350bc4bead6 391 SUPERFAMILY SSF53383 19 388 2.53E-62 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L04_02425 ceb45d700f6cb712081990dad740aefb 431 Pfam PF03129 Anticodon binding domain 339 426 1.0E-16 T 23-10-2018 IPR004154 Anticodon-binding A3L04_02425 ceb45d700f6cb712081990dad740aefb 431 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 14 378 26.316 T 23-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 A3L04_02425 ceb45d700f6cb712081990dad740aefb 431 Gene3D G3DSA:3.30.930.10 1 326 2.5E-112 T 23-10-2018 A3L04_02425 ceb45d700f6cb712081990dad740aefb 431 PIRSF PIRSF001549 1 428 4.2E-142 T 23-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 A3L04_02425 ceb45d700f6cb712081990dad740aefb 431 SUPERFAMILY SSF52954 338 429 1.81E-22 T 23-10-2018 A3L04_02425 ceb45d700f6cb712081990dad740aefb 431 Pfam PF13393 Histidyl-tRNA synthetase 7 321 1.9E-67 T 23-10-2018 A3L04_02425 ceb45d700f6cb712081990dad740aefb 431 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 417 3.2E-131 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A3L04_02425 ceb45d700f6cb712081990dad740aefb 431 SUPERFAMILY SSF55681 2 331 1.21E-88 T 23-10-2018 A3L04_02425 ceb45d700f6cb712081990dad740aefb 431 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 427 30.63 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A3L04_02425 ceb45d700f6cb712081990dad740aefb 431 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 9 324 2.1E-86 T 23-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 A3L04_02425 ceb45d700f6cb712081990dad740aefb 431 Gene3D G3DSA:3.40.50.800 337 428 6.6E-25 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A3L04_10060 13e00ed42eef50e9b67a758219c187dd 375 PIRSF PIRSF015647 5 375 2.5E-191 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L04_10060 13e00ed42eef50e9b67a758219c187dd 375 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 5 372 61.39 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L04_10060 13e00ed42eef50e9b67a758219c187dd 375 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 6 371 0.0 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L04_10060 13e00ed42eef50e9b67a758219c187dd 375 SUPERFAMILY SSF111249 6 372 1.7E-175 T 23-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L04_10060 13e00ed42eef50e9b67a758219c187dd 375 Pfam PF01950 Fructose-1,6-bisphosphatase 6 372 6.6E-185 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L04_03000 6c460d710b80533d757dafff362b5bd8 413 Pfam PF04894 Archaeal Nre, N-terminal 18 283 1.1E-102 T 23-10-2018 IPR006978 Archaeal Nre, N-terminal A3L04_03000 6c460d710b80533d757dafff362b5bd8 413 Pfam PF04895 Archaeal Nre, C-terminal 295 404 5.3E-38 T 23-10-2018 IPR006979 Archaeal Nre, C-terminal A3L04_03000 6c460d710b80533d757dafff362b5bd8 413 Hamap MF_02096 DNA repair protein. 1 404 39.889 T 23-10-2018 IPR033167 Archaeal Nre GO:0006281 A3L04_05080 2c2829ffcaacd6eb49a42cbbec556e6a 224 Gene3D G3DSA:3.40.50.300 13 222 1.0E-6 T 23-10-2018 A3L04_07775 c5d63032f4b596b20a7663953fca5913 646 Gene3D G3DSA:1.10.8.50 151 239 1.6E-5 T 23-10-2018 A3L04_07775 c5d63032f4b596b20a7663953fca5913 646 Gene3D G3DSA:2.30.310.10 4 150 1.8E-27 T 23-10-2018 A3L04_07775 c5d63032f4b596b20a7663953fca5913 646 SUPERFAMILY SSF46946 158 221 2.49E-7 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A3L04_07775 c5d63032f4b596b20a7663953fca5913 646 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 7 443 3.9E-79 T 23-10-2018 A3L04_07775 c5d63032f4b596b20a7663953fca5913 646 Pfam PF05670 Domain of unknown function (DUF814) 451 550 3.9E-26 T 23-10-2018 IPR008532 Domain of unknown function DUF814 A3L04_07175 946a7524a9defa34c9ae619d010eaad0 189 SUPERFAMILY SSF52317 1 185 1.26E-55 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L04_07175 946a7524a9defa34c9ae619d010eaad0 189 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 1.5E-5 T 23-10-2018 A3L04_07175 946a7524a9defa34c9ae619d010eaad0 189 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 73 89 1.5E-5 T 23-10-2018 A3L04_07175 946a7524a9defa34c9ae619d010eaad0 189 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 2 186 1.8E-83 T 23-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A3L04_07175 946a7524a9defa34c9ae619d010eaad0 189 PRINTS PR00097 Anthranilate synthase component II signature 2 16 6.0E-12 T 23-10-2018 A3L04_07175 946a7524a9defa34c9ae619d010eaad0 189 PRINTS PR00097 Anthranilate synthase component II signature 46 55 6.0E-12 T 23-10-2018 A3L04_07175 946a7524a9defa34c9ae619d010eaad0 189 PRINTS PR00097 Anthranilate synthase component II signature 73 84 6.0E-12 T 23-10-2018 A3L04_07175 946a7524a9defa34c9ae619d010eaad0 189 PRINTS PR00097 Anthranilate synthase component II signature 161 174 6.0E-12 T 23-10-2018 A3L04_07175 946a7524a9defa34c9ae619d010eaad0 189 Gene3D G3DSA:3.40.50.880 1 187 6.2E-63 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L04_07175 946a7524a9defa34c9ae619d010eaad0 189 Pfam PF00117 Glutamine amidotransferase class-I 4 182 8.0E-47 T 23-10-2018 IPR017926 Glutamine amidotransferase A3L04_07175 946a7524a9defa34c9ae619d010eaad0 189 Hamap MF_01510 GMP synthase [glutamine-hydrolyzing] subunit A [guaAA]. 1 187 45.46 T 23-10-2018 IPR023686 GMP synthase (glutamine-hydrolyzing) subunit A GO:0003922 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 A3L04_07175 946a7524a9defa34c9ae619d010eaad0 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 2.8E-10 T 23-10-2018 A3L04_07175 946a7524a9defa34c9ae619d010eaad0 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 73 84 2.8E-10 T 23-10-2018 A3L04_07175 946a7524a9defa34c9ae619d010eaad0 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 161 174 2.8E-10 T 23-10-2018 A3L04_03250 2b0c7b69ccd80cc4fd42ada096aa1f70 189 Pfam PF02517 CAAX protease self-immunity 103 177 7.2E-7 T 23-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A3L04_10265 160436d873488e7d3d41c5882453246c 198 ProDom PD016584 UPF0106 MK0803 MM0086 METAL MA3241 UNCHARACTERIZED DOMAIN TA0931 APE2006 ST0333 54 176 2.0E-57 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A3L04_10265 160436d873488e7d3d41c5882453246c 198 Hamap MF_00077 tRNA (cytidine(56)-2'-O)-methyltransferase. 1 175 43.998 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A3L04_10265 160436d873488e7d3d41c5882453246c 198 Pfam PF01994 tRNA ribose 2'-O-methyltransferase, aTrm56 55 173 2.3E-50 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A3L04_10265 160436d873488e7d3d41c5882453246c 198 PIRSF PIRSF016123 1 178 6.2E-87 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A3L04_10265 160436d873488e7d3d41c5882453246c 198 Gene3D G3DSA:3.40.1280.10 1 176 5.9E-82 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L04_10265 160436d873488e7d3d41c5882453246c 198 SUPERFAMILY SSF75217 1 173 6.02E-70 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L04_03100 800483919b7e3c0ea2948ac54303305a 334 SMART SM00846 3 141 4.3E-24 T 23-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_03100 800483919b7e3c0ea2948ac54303305a 334 Hamap MF_00559 Glyceraldehyde-3-phosphate dehydrogenase [gap]. 1 334 191.861 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 A3L04_03100 800483919b7e3c0ea2948ac54303305a 334 Gene3D G3DSA:3.30.360.10 140 301 4.9E-149 T 23-10-2018 A3L04_03100 800483919b7e3c0ea2948ac54303305a 334 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 120 2.4E-14 T 23-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A3L04_03100 800483919b7e3c0ea2948ac54303305a 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 146 296 9.4E-31 T 23-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_03100 800483919b7e3c0ea2948ac54303305a 334 SUPERFAMILY SSF51735 3 158 2.0E-49 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_03100 800483919b7e3c0ea2948ac54303305a 334 Gene3D G3DSA:3.40.50.720 3 331 4.9E-149 T 23-10-2018 A3L04_03100 800483919b7e3c0ea2948ac54303305a 334 SUPERFAMILY SSF55347 140 301 4.86E-52 T 23-10-2018 A3L04_03100 800483919b7e3c0ea2948ac54303305a 334 TIGRFAM TIGR01546 GAPDH-II_archae: glyceraldehyde-3-phosphate dehydrogenase, type II 5 333 1.4E-183 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 A3L04_03100 800483919b7e3c0ea2948ac54303305a 334 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 139 146 - T 23-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_03100 800483919b7e3c0ea2948ac54303305a 334 PIRSF PIRSF000149 1 318 9.3E-87 T 23-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_07635 21b353914759c898b6a31d71a8c3d7ad 454 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 261 298 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L04_07635 21b353914759c898b6a31d71a8c3d7ad 454 PIRSF PIRSF000521 2 144 2.6E-15 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L04_07635 21b353914759c898b6a31d71a8c3d7ad 454 PIRSF PIRSF000521 139 445 2.6E-50 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L04_07635 21b353914759c898b6a31d71a8c3d7ad 454 Gene3D G3DSA:3.90.1150.10 14 440 1.0E-153 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L04_07635 21b353914759c898b6a31d71a8c3d7ad 454 SUPERFAMILY SSF53383 30 443 4.59E-129 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L04_07635 21b353914759c898b6a31d71a8c3d7ad 454 Pfam PF00202 Aminotransferase class-III 34 442 2.2E-116 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L04_07635 21b353914759c898b6a31d71a8c3d7ad 454 Gene3D G3DSA:3.40.640.10 72 341 1.0E-153 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L04_02995 c68885515059ce691dcff2e32cbe081d 80 Pfam PF01037 Lrp/AsnC ligand binding domain 6 76 1.1E-15 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L04_02995 c68885515059ce691dcff2e32cbe081d 80 Gene3D G3DSA:3.30.70.920 1 73 1.0E-21 T 23-10-2018 A3L04_02995 c68885515059ce691dcff2e32cbe081d 80 SUPERFAMILY SSF54909 1 76 9.25E-17 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L04_04245 106cb4cf8f554862a2a4c0ff4d912db7 281 Gene3D G3DSA:3.40.50.970 86 277 5.0E-31 T 23-10-2018 A3L04_04245 106cb4cf8f554862a2a4c0ff4d912db7 281 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 56 202 1.4E-36 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L04_04245 106cb4cf8f554862a2a4c0ff4d912db7 281 SUPERFAMILY SSF52518 19 270 6.85E-78 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L04_05075 43c2c3ab8a659f2f4b149ed43a571196 99 Gene3D G3DSA:1.10.1200.200 1 99 3.9E-35 T 23-10-2018 A3L04_05075 43c2c3ab8a659f2f4b149ed43a571196 99 Pfam PF11537 Protein of unknown function (DUF3227) 3 94 4.7E-35 T 23-10-2018 IPR021609 Protein of unknown function DUF3227 A3L04_07750 59d6dced61464580f8c0757fd23c2ae2 348 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 4 341 1.3E-115 T 23-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme A3L04_07750 59d6dced61464580f8c0757fd23c2ae2 348 PIRSF PIRSF004869 1 313 3.3E-101 T 23-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted A3L04_07750 59d6dced61464580f8c0757fd23c2ae2 348 SUPERFAMILY SSF102114 41 315 6.41E-38 T 23-10-2018 A3L04_07750 59d6dced61464580f8c0757fd23c2ae2 348 Pfam PF04055 Radical SAM superfamily 79 235 1.2E-22 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_07750 59d6dced61464580f8c0757fd23c2ae2 348 Gene3D G3DSA:3.20.20.70 62 286 1.3E-38 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_07750 59d6dced61464580f8c0757fd23c2ae2 348 SMART SM00729 72 278 0.0038 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L04_07750 59d6dced61464580f8c0757fd23c2ae2 348 Pfam PF13353 4Fe-4S single cluster domain 75 168 1.7E-7 T 23-10-2018 A3L04_00820 9d2c7fabf299d527abeee526abdcf923 159 SMART SM01386 1 61 5.8E-34 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_00820 9d2c7fabf299d527abeee526abdcf923 159 Gene3D G3DSA:1.10.8.1030 36 90 8.9E-13 T 23-10-2018 A3L04_00820 9d2c7fabf299d527abeee526abdcf923 159 ProSitePatterns PS00362 Ribosomal protein S15 signature. 106 136 - T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_00820 9d2c7fabf299d527abeee526abdcf923 159 Pfam PF00312 Ribosomal protein S15 81 156 5.0E-20 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_00820 9d2c7fabf299d527abeee526abdcf923 159 Gene3D G3DSA:1.10.287.10 91 159 2.1E-32 T 23-10-2018 A3L04_00820 9d2c7fabf299d527abeee526abdcf923 159 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 91 159 6.0E-4 T 23-10-2018 A3L04_00820 9d2c7fabf299d527abeee526abdcf923 159 Pfam PF08069 Ribosomal S13/S15 N-terminal domain 1 61 4.5E-26 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_00820 9d2c7fabf299d527abeee526abdcf923 159 SUPERFAMILY SSF47060 77 150 5.59E-23 T 23-10-2018 IPR009068 S15/NS1, RNA-binding A3L04_00820 9d2c7fabf299d527abeee526abdcf923 159 Hamap MF_01343_A 30S ribosomal protein S15 [rpsO]. 3 157 33.266 T 23-10-2018 IPR023029 Ribosomal protein S15P Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_00820 9d2c7fabf299d527abeee526abdcf923 159 SMART SM01387 79 157 1.6E-25 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_07045 9c1b3345b38c57433cce75d595e3d68e 491 SUPERFAMILY SSF51905 108 368 1.87E-21 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_07045 9c1b3345b38c57433cce75d595e3d68e 491 Gene3D G3DSA:1.10.10.1100 397 473 2.0E-148 T 23-10-2018 A3L04_07045 9c1b3345b38c57433cce75d595e3d68e 491 Gene3D G3DSA:3.50.50.60 218 308 2.0E-148 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_07045 9c1b3345b38c57433cce75d595e3d68e 491 Gene3D G3DSA:3.50.50.60 109 480 2.0E-148 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_07045 9c1b3345b38c57433cce75d595e3d68e 491 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 259 351 2.0E-8 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L04_07045 9c1b3345b38c57433cce75d595e3d68e 491 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 12 86 9.3E-14 T 23-10-2018 A3L04_07045 9c1b3345b38c57433cce75d595e3d68e 491 Gene3D G3DSA:3.10.20.440 1 94 2.0E-38 T 23-10-2018 A3L04_07045 9c1b3345b38c57433cce75d595e3d68e 491 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 109 230 6.7E-12 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L04_07045 9c1b3345b38c57433cce75d595e3d68e 491 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 110 129 1.5E-7 T 23-10-2018 A3L04_07045 9c1b3345b38c57433cce75d595e3d68e 491 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 206 224 1.5E-7 T 23-10-2018 A3L04_07045 9c1b3345b38c57433cce75d595e3d68e 491 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 300 316 1.5E-7 T 23-10-2018 A3L04_00670 50f78d788dccb58f899c6c4698c5c1de 95 Gene3D G3DSA:3.30.1360.10 1 94 3.6E-33 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_00670 50f78d788dccb58f899c6c4698c5c1de 95 Hamap MF_00261 DNA-directed RNA polymerase subunit L [rpoL]. 1 89 20.785 T 23-10-2018 IPR022905 DNA-directed RNA polymerase subunit L (Rpo11) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_00670 50f78d788dccb58f899c6c4698c5c1de 95 SUPERFAMILY SSF55257 1 94 4.84E-25 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_00670 50f78d788dccb58f899c6c4698c5c1de 95 ProSitePatterns PS01154 RNA polymerases L / 13 to 16 Kd subunits signature. 17 48 - T 23-10-2018 IPR008193 DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 A3L04_00670 50f78d788dccb58f899c6c4698c5c1de 95 Pfam PF13656 RNA polymerase Rpb3/Rpb11 dimerisation domain 13 86 9.7E-19 T 23-10-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 A3L04_04185 8d7846f68742ad1b70e5da9daf7f48e8 375 Gene3D G3DSA:3.40.50.10330 85 202 4.4E-7 T 23-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A3L04_04185 8d7846f68742ad1b70e5da9daf7f48e8 375 Pfam PF01513 ATP-NAD kinase 2 374 3.0E-51 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A3L04_04185 8d7846f68742ad1b70e5da9daf7f48e8 375 PIRSF PIRSF016907 1 375 1.7E-150 T 23-10-2018 IPR011386 Putative ATP-NAD kinase A3L04_04185 8d7846f68742ad1b70e5da9daf7f48e8 375 SUPERFAMILY SSF111331 96 174 4.97E-8 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A3L04_01735 e30b951af5d0983a27a986a2b2f03096 171 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 165 3.7E-15 T 23-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase A3L04_02630 ba9ab89ff9e49dd38c14cba4a5b0115a 67 SUPERFAMILY SSF88723 3 62 3.6E-10 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_02630 ba9ab89ff9e49dd38c14cba4a5b0115a 67 Gene3D G3DSA:3.40.50.1010 1 66 2.2E-8 T 23-10-2018 A3L04_02630 ba9ab89ff9e49dd38c14cba4a5b0115a 67 Pfam PF01850 PIN domain 5 62 7.3E-15 T 23-10-2018 IPR002716 PIN domain A3L04_04515 fe011464b2022e76b537faac6e7f02c5 383 Gene3D G3DSA:3.30.360.10 217 320 1.0E-128 T 23-10-2018 A3L04_04515 fe011464b2022e76b537faac6e7f02c5 383 PIRSF PIRSF015578 1 380 2.0E-94 T 23-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A3L04_04515 fe011464b2022e76b537faac6e7f02c5 383 SUPERFAMILY SSF55347 212 317 9.42E-30 T 23-10-2018 A3L04_04515 fe011464b2022e76b537faac6e7f02c5 383 SUPERFAMILY SSF51735 1 378 1.73E-71 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_04515 fe011464b2022e76b537faac6e7f02c5 383 Gene3D G3DSA:3.40.50.720 3 355 1.0E-128 T 23-10-2018 A3L04_04515 fe011464b2022e76b537faac6e7f02c5 383 Pfam PF01658 Myo-inositol-1-phosphate synthase 213 318 7.7E-21 T 23-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A3L04_04515 fe011464b2022e76b537faac6e7f02c5 383 Pfam PF07994 Myo-inositol-1-phosphate synthase 127 356 5.4E-10 T 23-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A3L04_07330 99c66f56d798ba775bf541c49bd8d5cc 134 SUPERFAMILY SSF51230 10 132 8.64E-43 T 23-10-2018 IPR011053 Single hybrid motif A3L04_07330 99c66f56d798ba775bf541c49bd8d5cc 134 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 54 83 - T 23-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A3L04_07330 99c66f56d798ba775bf541c49bd8d5cc 134 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 11 132 3.6E-47 T 23-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A3L04_07330 99c66f56d798ba775bf541c49bd8d5cc 134 Pfam PF01597 Glycine cleavage H-protein 13 133 9.1E-52 T 23-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate A3L04_07330 99c66f56d798ba775bf541c49bd8d5cc 134 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 10 132 42.689 T 23-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A3L04_07330 99c66f56d798ba775bf541c49bd8d5cc 134 Gene3D G3DSA:2.40.50.100 3 133 4.9E-52 T 23-10-2018 A3L04_02930 50288fe3cd8b6e2a9736a777f4fe6e67 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 324 1.4E-46 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L04_02930 50288fe3cd8b6e2a9736a777f4fe6e67 330 SUPERFAMILY SSF161098 99 312 1.11E-8 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_02930 50288fe3cd8b6e2a9736a777f4fe6e67 330 Gene3D G3DSA:1.10.3720.10 91 326 2.9E-10 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_05875 c0f67f859143836460e20893372d6639 311 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 72 218 2.5E-20 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L04_05875 c0f67f859143836460e20893372d6639 311 Gene3D G3DSA:3.40.50.970 6 100 6.0E-6 T 23-10-2018 A3L04_05875 c0f67f859143836460e20893372d6639 311 Gene3D G3DSA:3.40.50.970 101 310 2.9E-69 T 23-10-2018 A3L04_05875 c0f67f859143836460e20893372d6639 311 SUPERFAMILY SSF52518 18 308 4.85E-73 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L04_07660 6cb10ab4fb530d865f557c25f04ff842 333 Gene3D G3DSA:3.30.300.110 58 143 1.5E-27 T 23-10-2018 A3L04_07660 6cb10ab4fb530d865f557c25f04ff842 333 SUPERFAMILY SSF53335 73 330 3.32E-70 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_07660 6cb10ab4fb530d865f557c25f04ff842 333 Gene3D G3DSA:3.30.70.2580 1 57 9.9E-9 T 23-10-2018 A3L04_07660 6cb10ab4fb530d865f557c25f04ff842 333 Pfam PF02475 Met-10+ like-protein 83 278 4.0E-70 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A3L04_07660 6cb10ab4fb530d865f557c25f04ff842 333 Gene3D G3DSA:3.40.50.150 144 332 3.1E-56 T 23-10-2018 A3L04_08545 3ebc5cc69e57498856dcc532ad872440 534 Gene3D G3DSA:3.40.50.300 132 235 3.1E-9 T 23-10-2018 A3L04_08545 3ebc5cc69e57498856dcc532ad872440 534 SUPERFAMILY SSF52540 140 491 1.48E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_08545 3ebc5cc69e57498856dcc532ad872440 534 Pfam PF01935 Domain of unknown function DUF87 144 364 1.4E-38 T 23-10-2018 IPR002789 Helicase HerA, central domain A3L04_08545 3ebc5cc69e57498856dcc532ad872440 534 Gene3D G3DSA:3.40.50.300 289 504 2.2E-57 T 23-10-2018 A3L04_08545 3ebc5cc69e57498856dcc532ad872440 534 Pfam PF09378 HAS barrel domain 14 104 3.8E-7 T 23-10-2018 IPR018538 Helicase HerA, barrel domain A3L04_07385 51c96e8388f22e94d0ae18d046c5ba38 562 SUPERFAMILY SSF51703 10 556 6.28E-230 T 23-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L04_07385 51c96e8388f22e94d0ae18d046c5ba38 562 Gene3D G3DSA:3.20.20.240 1 562 2.3E-269 T 23-10-2018 A3L04_07385 51c96e8388f22e94d0ae18d046c5ba38 562 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 37 560 1.1E-293 T 23-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L04_07385 51c96e8388f22e94d0ae18d046c5ba38 562 Pfam PF01642 Methylmalonyl-CoA mutase 39 554 5.1E-240 T 23-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L04_02225 9c186ae258d5b3629f8d5389136c9f72 235 SUPERFAMILY SSF55307 144 232 2.17E-11 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A3L04_02225 9c186ae258d5b3629f8d5389136c9f72 235 Gene3D G3DSA:3.40.50.1440 106 233 3.3E-7 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L04_10030 1e424db97eef56b135338f12694c6c79 139 Hamap MF_00620 Putative transcriptional regulatory protein . 1 133 30.53 T 23-10-2018 IPR018384 DNA-binding protein Tfx, euryarchaeota GO:0003677 A3L04_10030 1e424db97eef56b135338f12694c6c79 139 Gene3D G3DSA:3.30.1190.10 15 133 2.5E-37 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 A3L04_10030 1e424db97eef56b135338f12694c6c79 139 SUPERFAMILY SSF89915 15 114 3.79E-25 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 A3L04_10030 1e424db97eef56b135338f12694c6c79 139 Pfam PF14601 DNA_binding protein, TFX, C-term 50 130 7.3E-25 T 23-10-2018 IPR029291 DNA binding protein Tfx, C-terminal A3L04_10030 1e424db97eef56b135338f12694c6c79 139 Pfam PF04545 Sigma-70, region 4 5 47 2.3E-7 T 23-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A3L04_10030 1e424db97eef56b135338f12694c6c79 139 PIRSF PIRSF004932 1 139 2.9E-67 T 23-10-2018 IPR018384 DNA-binding protein Tfx, euryarchaeota GO:0003677 A3L04_10030 1e424db97eef56b135338f12694c6c79 139 TIGRFAM TIGR00721 tfx: DNA-binding protein, Tfx family 1 136 1.5E-60 T 23-10-2018 IPR004645 DNA-binding protein Tfx, archaea GO:0003677 A3L04_08340 d73f0a41d7f8a2e9def402047ed75562 522 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 442 1.9E-104 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain A3L04_08340 d73f0a41d7f8a2e9def402047ed75562 522 SUPERFAMILY SSF53850 40 520 1.78E-145 T 23-10-2018 A3L04_08340 d73f0a41d7f8a2e9def402047ed75562 522 PIRSF PIRSF002741 1 519 2.6E-115 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A3L04_08340 d73f0a41d7f8a2e9def402047ed75562 522 Gene3D G3DSA:3.90.76.10 53 195 2.0E-143 T 23-10-2018 A3L04_08340 d73f0a41d7f8a2e9def402047ed75562 522 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 87 109 - T 23-10-2018 IPR023765 Solute-binding protein family 5, conserved site A3L04_08340 d73f0a41d7f8a2e9def402047ed75562 522 Gene3D G3DSA:3.40.190.10 196 507 2.0E-143 T 23-10-2018 A3L04_08340 d73f0a41d7f8a2e9def402047ed75562 522 Gene3D G3DSA:3.10.105.10 278 497 2.0E-143 T 23-10-2018 A3L04_07225 23bbf82dc9748fd222d55ae507799edd 370 PRINTS PR00423 Cell division protein FtsZ signature 183 205 3.4E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L04_07225 23bbf82dc9748fd222d55ae507799edd 370 PRINTS PR00423 Cell division protein FtsZ signature 93 113 3.4E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L04_07225 23bbf82dc9748fd222d55ae507799edd 370 PRINTS PR00423 Cell division protein FtsZ signature 123 144 3.4E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L04_07225 23bbf82dc9748fd222d55ae507799edd 370 Gene3D G3DSA:3.40.50.1440 1 363 1.7E-87 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L04_07225 23bbf82dc9748fd222d55ae507799edd 370 Hamap MF_01946 Tubulin-like protein CetZ [cetZ]. 1 354 26.72 T 23-10-2018 IPR032907 Tubulin-like protein CetZ GO:0008360 A3L04_07225 23bbf82dc9748fd222d55ae507799edd 370 ProSitePatterns PS00227 Tubulin subunits alpha, beta, and gamma signature. 101 107 - T 23-10-2018 IPR017975 Tubulin, conserved site GO:0005525|GO:0005874|GO:0007017 Reactome: R-HSA-380320 A3L04_07225 23bbf82dc9748fd222d55ae507799edd 370 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 4 168 2.5E-26 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L04_07225 23bbf82dc9748fd222d55ae507799edd 370 SUPERFAMILY SSF52490 2 199 9.55E-41 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L04_07225 23bbf82dc9748fd222d55ae507799edd 370 SMART SM00864 2 199 7.4E-34 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L04_07445 f3b0f159bdfc0b11076287f1a3c305af 438 TIGRFAM TIGR02153 gatD_arch: glutamyl-tRNA(Gln) amidotransferase, subunit D 31 432 3.1E-202 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 A3L04_07445 f3b0f159bdfc0b11076287f1a3c305af 438 PIRSF PIRSF001220 89 427 1.8E-113 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L04_07445 f3b0f159bdfc0b11076287f1a3c305af 438 Gene3D G3DSA:2.30.30.520 1 78 1.7E-27 T 23-10-2018 IPR037222 GatD, N-terminal A3L04_07445 f3b0f159bdfc0b11076287f1a3c305af 438 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 91 428 2.0E-146 T 23-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 A3L04_07445 f3b0f159bdfc0b11076287f1a3c305af 438 SUPERFAMILY SSF141300 3 74 9.16E-22 T 23-10-2018 IPR037222 GatD, N-terminal A3L04_07445 f3b0f159bdfc0b11076287f1a3c305af 438 SMART SM00870 93 416 1.2E-155 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L04_07445 f3b0f159bdfc0b11076287f1a3c305af 438 Gene3D G3DSA:3.40.50.1170 79 300 1.2E-87 T 23-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 A3L04_07445 f3b0f159bdfc0b11076287f1a3c305af 438 Hamap MF_00586 Glutamyl-tRNA(Gln) amidotransferase subunit D [gatD]. 18 432 49.993 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 A3L04_07445 f3b0f159bdfc0b11076287f1a3c305af 438 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 96 104 - T 23-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 A3L04_07445 f3b0f159bdfc0b11076287f1a3c305af 438 Pfam PF00710 Asparaginase, N-terminal 94 286 7.7E-62 T 23-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A3L04_07445 f3b0f159bdfc0b11076287f1a3c305af 438 SUPERFAMILY SSF53774 87 434 9.29E-119 T 23-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 A3L04_07445 f3b0f159bdfc0b11076287f1a3c305af 438 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 171 181 - T 23-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 A3L04_07445 f3b0f159bdfc0b11076287f1a3c305af 438 PRINTS PR00139 Asparaginase/glutaminase family signature 170 188 1.7E-17 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L04_07445 f3b0f159bdfc0b11076287f1a3c305af 438 PRINTS PR00139 Asparaginase/glutaminase family signature 353 371 1.7E-17 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L04_07445 f3b0f159bdfc0b11076287f1a3c305af 438 PRINTS PR00139 Asparaginase/glutaminase family signature 94 105 1.7E-17 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L04_07445 f3b0f159bdfc0b11076287f1a3c305af 438 PIRSF PIRSF500175 12 436 4.0E-193 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 A3L04_07445 f3b0f159bdfc0b11076287f1a3c305af 438 Gene3D G3DSA:3.40.50.40 301 438 5.0E-58 T 23-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 A3L04_05425 b94714dbac4a58ff32802dcba52559b0 307 SUPERFAMILY SSF56281 1 245 6.36E-15 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_05425 b94714dbac4a58ff32802dcba52559b0 307 Gene3D G3DSA:3.60.15.10 7 268 7.8E-16 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_05425 b94714dbac4a58ff32802dcba52559b0 307 Hamap MF_01406 UPF0282 protein . 1 286 38.708 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase A3L04_05425 b94714dbac4a58ff32802dcba52559b0 307 PIRSF PIRSF004944 1 307 5.2E-128 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase A3L04_07510 3a8630f8da6531c5af8c0940ed6368f2 617 Pfam PF00361 Proton-conducting membrane transporter 116 423 2.2E-61 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07505 7374305b2d831e7e6f6eec66b31191b4 493 Pfam PF00361 Proton-conducting membrane transporter 129 417 4.4E-66 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07505 7374305b2d831e7e6f6eec66b31191b4 493 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 77 102 1.1E-10 T 23-10-2018 A3L04_07505 7374305b2d831e7e6f6eec66b31191b4 493 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 412 431 1.1E-10 T 23-10-2018 A3L04_07505 7374305b2d831e7e6f6eec66b31191b4 493 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 215 236 1.1E-10 T 23-10-2018 A3L04_07505 7374305b2d831e7e6f6eec66b31191b4 493 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 237 263 1.1E-10 T 23-10-2018 A3L04_07505 7374305b2d831e7e6f6eec66b31191b4 493 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 150 171 1.1E-10 T 23-10-2018 A3L04_07505 7374305b2d831e7e6f6eec66b31191b4 493 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 308 320 1.1E-10 T 23-10-2018 A3L04_09540 c9efd90e96a261f8be10234fe8fa9ff2 461 Pfam PF03008 Archaea bacterial proteins of unknown function 309 406 4.0E-33 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L04_09540 c9efd90e96a261f8be10234fe8fa9ff2 461 SUPERFAMILY SSF52980 339 412 5.23E-6 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L04_09540 c9efd90e96a261f8be10234fe8fa9ff2 461 SUPERFAMILY SSF52540 5 244 8.11E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09540 c9efd90e96a261f8be10234fe8fa9ff2 461 Gene3D G3DSA:1.10.10.10 241 311 7.5E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_09540 c9efd90e96a261f8be10234fe8fa9ff2 461 Pfam PF01637 ATPase domain predominantly from Archaea 7 203 2.7E-23 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_09540 c9efd90e96a261f8be10234fe8fa9ff2 461 SUPERFAMILY SSF46785 244 354 1.57E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_09540 c9efd90e96a261f8be10234fe8fa9ff2 461 Gene3D G3DSA:3.40.50.300 4 78 2.0E-10 T 23-10-2018 A3L04_09540 c9efd90e96a261f8be10234fe8fa9ff2 461 Gene3D G3DSA:3.40.50.300 79 170 1.9E-17 T 23-10-2018 A3L04_02865 28ce0c8ddd288b46123b18a54a714125 208 Pfam PF04509 CheC-like family 10 42 7.1E-5 T 23-10-2018 IPR007597 CheC-like protein GO:0016787 A3L04_02865 28ce0c8ddd288b46123b18a54a714125 208 SUPERFAMILY SSF103039 4 198 1.11E-39 T 23-10-2018 IPR028976 CheC-like superfamily A3L04_02865 28ce0c8ddd288b46123b18a54a714125 208 Gene3D G3DSA:3.40.1550.10 1 199 8.6E-44 T 23-10-2018 IPR028976 CheC-like superfamily A3L04_02865 28ce0c8ddd288b46123b18a54a714125 208 Pfam PF13690 Chemotaxis phosphatase CheX 63 143 2.6E-8 T 23-10-2018 IPR028051 Chemotaxis phosphatase CheX-like domain A3L04_05120 1e6a126980b09decc709a12ba2237b46 433 Pfam PF01555 DNA methylase 32 98 6.9E-9 T 23-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 A3L04_05120 1e6a126980b09decc709a12ba2237b46 433 SUPERFAMILY SSF53335 57 278 2.39E-16 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_05120 1e6a126980b09decc709a12ba2237b46 433 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 258 270 6.8E-5 T 23-10-2018 A3L04_05120 1e6a126980b09decc709a12ba2237b46 433 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 67 81 6.8E-5 T 23-10-2018 A3L04_05120 1e6a126980b09decc709a12ba2237b46 433 SUPERFAMILY SSF53335 248 413 3.45E-8 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_05120 1e6a126980b09decc709a12ba2237b46 433 Gene3D G3DSA:3.40.50.150 5 129 3.5E-17 T 23-10-2018 A3L04_05120 1e6a126980b09decc709a12ba2237b46 433 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 262 267 - T 23-10-2018 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 A3L04_03960 1859342dc87fd9ae96430804c323ab5b 373 SMART SM01097 4 142 1.6E-78 T 23-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_03960 1859342dc87fd9ae96430804c323ab5b 373 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 7 141 2.4E-47 T 23-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_03960 1859342dc87fd9ae96430804c323ab5b 373 SUPERFAMILY SSF52021 6 156 8.76E-50 T 23-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_03960 1859342dc87fd9ae96430804c323ab5b 373 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 7 368 1.1E-125 T 23-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_03960 1859342dc87fd9ae96430804c323ab5b 373 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 187 201 7.6E-33 T 23-10-2018 A3L04_03960 1859342dc87fd9ae96430804c323ab5b 373 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 275 292 7.6E-33 T 23-10-2018 A3L04_03960 1859342dc87fd9ae96430804c323ab5b 373 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 258 274 7.6E-33 T 23-10-2018 A3L04_03960 1859342dc87fd9ae96430804c323ab5b 373 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 227 241 7.6E-33 T 23-10-2018 A3L04_03960 1859342dc87fd9ae96430804c323ab5b 373 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 300 311 7.6E-33 T 23-10-2018 A3L04_03960 1859342dc87fd9ae96430804c323ab5b 373 Pfam PF00117 Glutamine amidotransferase class-I 189 365 1.7E-39 T 23-10-2018 IPR017926 Glutamine amidotransferase A3L04_03960 1859342dc87fd9ae96430804c323ab5b 373 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 4 371 43.475 T 23-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_03960 1859342dc87fd9ae96430804c323ab5b 373 Gene3D G3DSA:3.50.30.20 4 158 4.6E-54 T 23-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L04_03960 1859342dc87fd9ae96430804c323ab5b 373 PRINTS PR00096 Glutamine amidotransferase superfamily signature 342 355 3.6E-9 T 23-10-2018 A3L04_03960 1859342dc87fd9ae96430804c323ab5b 373 PRINTS PR00096 Glutamine amidotransferase superfamily signature 230 239 3.6E-9 T 23-10-2018 A3L04_03960 1859342dc87fd9ae96430804c323ab5b 373 PRINTS PR00096 Glutamine amidotransferase superfamily signature 258 269 3.6E-9 T 23-10-2018 A3L04_03960 1859342dc87fd9ae96430804c323ab5b 373 Gene3D G3DSA:3.40.50.880 159 369 2.3E-53 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L04_03960 1859342dc87fd9ae96430804c323ab5b 373 SUPERFAMILY SSF52317 155 369 1.28E-49 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L04_03450 c4ccd249777abad0eeade344babec4a2 56 Pfam PF00253 Ribosomal protein S14p/S29e 8 55 8.5E-9 T 23-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_03450 c4ccd249777abad0eeade344babec4a2 56 Hamap MF_01364_A 30S ribosomal protein S14 type Z [rpsZ]. 2 56 17.461 T 23-10-2018 IPR023676 Ribosomal protein S14, type Z, archaeal GO:0003723|GO:0003735|GO:0006412|GO:0015935 A3L04_03450 c4ccd249777abad0eeade344babec4a2 56 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 44 - T 23-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03450 c4ccd249777abad0eeade344babec4a2 56 Gene3D G3DSA:4.10.830.10 1 56 1.0E-19 T 23-10-2018 A3L04_09070 c0d09b90a2718d7a9bf0473dc52982de 356 TIGRFAM TIGR01888 cas_cmr3: CRISPR type III-B/RAMP module-associated protein Cmr3 4 356 1.5E-60 T 23-10-2018 IPR010165 CRISPR-associated protein, TM1793 A3L04_09070 c0d09b90a2718d7a9bf0473dc52982de 356 Gene3D G3DSA:3.30.70.2950 256 356 1.6E-33 T 23-10-2018 A3L04_09070 c0d09b90a2718d7a9bf0473dc52982de 356 Pfam PF09700 CRISPR-associated protein (Cas_Cmr3) 4 356 4.6E-65 T 23-10-2018 IPR019117 CRISPR-associated protein, Cmr3 A3L04_09070 c0d09b90a2718d7a9bf0473dc52982de 356 Gene3D G3DSA:3.30.70.2940 1 91 4.0E-16 T 23-10-2018 A3L04_04900 4ce4af1cd1a99607556b8fcc8aa4eb71 172 Pfam PF00881 Nitroreductase family 70 147 3.9E-15 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A3L04_04900 4ce4af1cd1a99607556b8fcc8aa4eb71 172 Pfam PF00881 Nitroreductase family 7 60 2.8E-18 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A3L04_04900 4ce4af1cd1a99607556b8fcc8aa4eb71 172 SUPERFAMILY SSF55469 2 169 1.57E-47 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L04_04900 4ce4af1cd1a99607556b8fcc8aa4eb71 172 Gene3D G3DSA:3.40.109.10 2 171 6.0E-51 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L04_02165 f30c31820a678ba102e8fc14f1f5cc5d 206 Pfam PF05175 Methyltransferase small domain 42 126 1.6E-12 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A3L04_02165 f30c31820a678ba102e8fc14f1f5cc5d 206 SUPERFAMILY SSF53335 4 199 3.9E-39 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_02165 f30c31820a678ba102e8fc14f1f5cc5d 206 SMART SM00650 36 186 0.0039 T 23-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 A3L04_02165 f30c31820a678ba102e8fc14f1f5cc5d 206 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 113 119 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A3L04_02165 f30c31820a678ba102e8fc14f1f5cc5d 206 Gene3D G3DSA:3.40.50.150 1 203 3.5E-67 T 23-10-2018 A3L04_09125 90a88a992a1d473d84c46014f4c2f6a8 941 Gene3D G3DSA:3.40.50.300 315 478 1.8E-5 T 23-10-2018 A3L04_09125 90a88a992a1d473d84c46014f4c2f6a8 941 SUPERFAMILY SSF52540 319 639 1.99E-15 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_05700 136b891dc77bc54df4a473ecde149bcf 100 Pfam PF01909 Nucleotidyltransferase domain 12 64 5.0E-8 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L04_05700 136b891dc77bc54df4a473ecde149bcf 100 SUPERFAMILY SSF81301 4 80 1.53E-13 T 23-10-2018 A3L04_05700 136b891dc77bc54df4a473ecde149bcf 100 Gene3D G3DSA:3.30.460.10 1 93 2.5E-15 T 23-10-2018 A3L04_09675 0fcbcb1c5188799137c127cc147469a0 740 Gene3D G3DSA:2.10.230.10 1 87 7.6E-7 T 23-10-2018 A3L04_09675 0fcbcb1c5188799137c127cc147469a0 740 Pfam PF00575 S1 RNA binding domain 130 193 3.8E-8 T 23-10-2018 IPR003029 S1 domain GO:0003676 A3L04_09675 0fcbcb1c5188799137c127cc147469a0 740 Gene3D G3DSA:2.40.50.140 128 200 4.6E-11 T 23-10-2018 A3L04_09675 0fcbcb1c5188799137c127cc147469a0 740 Gene3D G3DSA:3.90.1640.30 334 529 1.8E-9 T 23-10-2018 A3L04_09675 0fcbcb1c5188799137c127cc147469a0 740 SUPERFAMILY SSF64182 337 733 9.68E-42 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L04_09675 0fcbcb1c5188799137c127cc147469a0 740 SUPERFAMILY SSF57938 4 84 1.31E-7 T 23-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily A3L04_09675 0fcbcb1c5188799137c127cc147469a0 740 SUPERFAMILY SSF50249 226 297 1.5E-10 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_09675 0fcbcb1c5188799137c127cc147469a0 740 SUPERFAMILY SSF50249 125 193 2.26E-9 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_09675 0fcbcb1c5188799137c127cc147469a0 740 SMART SM00316 131 196 2.6E-11 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L04_09675 0fcbcb1c5188799137c127cc147469a0 740 Gene3D G3DSA:2.40.50.140 219 304 4.1E-7 T 23-10-2018 A3L04_09675 0fcbcb1c5188799137c127cc147469a0 740 Pfam PF01336 OB-fold nucleic acid binding domain 227 293 1.9E-9 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L04_01915 16a60fc8339f4335c5d9a10c51209178 455 PIRSF PIRSF004919 1 455 7.8E-165 T 23-10-2018 IPR025502 TldD A3L04_01915 16a60fc8339f4335c5d9a10c51209178 455 Pfam PF01523 Putative modulator of DNA gyrase 22 309 3.7E-62 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L04_01915 16a60fc8339f4335c5d9a10c51209178 455 SUPERFAMILY SSF111283 1 449 7.72E-116 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L04_01915 16a60fc8339f4335c5d9a10c51209178 455 Gene3D G3DSA:3.30.2290.10 1 196 1.7E-20 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L04_05295 f446393d41b3cf1bdddbeda676fbd00e 216 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 155 195 2.0E-8 T 23-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L04_05295 f446393d41b3cf1bdddbeda676fbd00e 216 SUPERFAMILY SSF52833 1 215 1.48E-63 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L04_05295 f446393d41b3cf1bdddbeda676fbd00e 216 Pfam PF00578 AhpC/TSA family 4 134 2.9E-32 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L04_05295 f446393d41b3cf1bdddbeda676fbd00e 216 Gene3D G3DSA:3.30.1020.10 145 216 9.0E-36 T 23-10-2018 A3L04_05295 f446393d41b3cf1bdddbeda676fbd00e 216 Hamap MF_00401 Peroxiredoxin. 2 215 52.497 T 23-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A3L04_05295 f446393d41b3cf1bdddbeda676fbd00e 216 PIRSF PIRSF000239 1 215 1.2E-71 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L04_05295 f446393d41b3cf1bdddbeda676fbd00e 216 Gene3D G3DSA:3.40.30.10 1 144 1.7E-44 T 23-10-2018 A3L04_09065 9085df8f3462585944225b5e2552550b 479 Gene3D G3DSA:1.10.3740.10 330 408 2.2E-12 T 23-10-2018 IPR027419 CRISPR-associated protein Csx1, C-terminal A3L04_09065 9085df8f3462585944225b5e2552550b 479 Gene3D G3DSA:3.40.50.10640 5 324 8.7E-95 T 23-10-2018 A3L04_09065 9085df8f3462585944225b5e2552550b 479 SUPERFAMILY SSF160980 7 462 7.19E-60 T 23-10-2018 A3L04_09065 9085df8f3462585944225b5e2552550b 479 TIGRFAM TIGR01897 cas_MJ1666: CRISPR-associated protein, MJ1666 family 8 461 1.1E-77 T 23-10-2018 IPR010171 CRISPR-associated protein, MJ1666 A3L04_09065 9085df8f3462585944225b5e2552550b 479 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 9 436 2.8E-23 T 23-10-2018 IPR019016 CRISPR-associated DxTHG protein A3L04_09065 9085df8f3462585944225b5e2552550b 479 TIGRFAM TIGR02549 CRISPR_DxTHG: CRISPR-associated DxTHG motif protein 191 211 7.9E-11 T 23-10-2018 IPR013383 CRISPR-associated protein DxTHG, conserved site A3L04_03545 acd0073e4291c5a0535f369decb2fbfb 90 Pfam PF04410 Gar1/Naf1 RNA binding region 2 77 2.2E-9 T 23-10-2018 IPR007504 H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 GO:0001522|GO:0042254 A3L04_03545 acd0073e4291c5a0535f369decb2fbfb 90 Gene3D G3DSA:2.40.10.230 1 75 2.0E-27 T 23-10-2018 IPR038664 H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain A3L04_03545 acd0073e4291c5a0535f369decb2fbfb 90 ProDom PD064583 RNA-BINDING GAR1 COMPONENT RNP SNORNP HOMOLOG NUCLEOLAR PROCESSING RRNA VNG1366H 1 71 4.0E-30 T 23-10-2018 IPR020321 H/ACA ribonucleoprotein complex, subunit Gar1, archaea GO:0001522|GO:0042254 A3L04_03545 acd0073e4291c5a0535f369decb2fbfb 90 SUPERFAMILY SSF50447 1 73 8.12E-18 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L04_00095 0db9df6fa7f75508bbe9b0b8078d81d5 67 Gene3D G3DSA:3.30.70.20 2 67 8.9E-26 T 23-10-2018 A3L04_00095 0db9df6fa7f75508bbe9b0b8078d81d5 67 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 6.5E-10 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A3L04_00095 0db9df6fa7f75508bbe9b0b8078d81d5 67 PRINTS PR00352 3Fe-4S ferredoxin signature 50 62 6.5E-10 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A3L04_00095 0db9df6fa7f75508bbe9b0b8078d81d5 67 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 6.5E-10 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A3L04_00095 0db9df6fa7f75508bbe9b0b8078d81d5 67 SUPERFAMILY SSF54862 3 65 1.31E-16 T 23-10-2018 A3L04_00095 0db9df6fa7f75508bbe9b0b8078d81d5 67 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 63 1.6E-18 T 23-10-2018 A3L04_10745 3b5c8a4b53ee15c8d27b8e64930a1325 431 Pfam PF03008 Archaea bacterial proteins of unknown function 295 385 1.6E-12 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L04_10745 3b5c8a4b53ee15c8d27b8e64930a1325 431 SUPERFAMILY SSF46785 232 346 6.12E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_10745 3b5c8a4b53ee15c8d27b8e64930a1325 431 Gene3D G3DSA:3.40.50.300 63 150 2.5E-13 T 23-10-2018 A3L04_10745 3b5c8a4b53ee15c8d27b8e64930a1325 431 Gene3D G3DSA:3.40.50.300 1 62 2.3E-6 T 23-10-2018 A3L04_10745 3b5c8a4b53ee15c8d27b8e64930a1325 431 Gene3D G3DSA:1.10.10.10 227 298 1.4E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_10745 3b5c8a4b53ee15c8d27b8e64930a1325 431 SUPERFAMILY SSF52540 1 222 8.43E-30 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_10745 3b5c8a4b53ee15c8d27b8e64930a1325 431 Pfam PF13173 AAA domain 19 156 2.7E-12 T 23-10-2018 A3L04_04990 65d6de626852b69744bdd1133e2e4240 485 Gene3D G3DSA:1.25.10.10 3 264 1.5E-18 T 23-10-2018 IPR011989 Armadillo-like helical A3L04_04990 65d6de626852b69744bdd1133e2e4240 485 SUPERFAMILY SSF48371 36 480 7.04E-36 T 23-10-2018 IPR016024 Armadillo-type fold A3L04_04990 65d6de626852b69744bdd1133e2e4240 485 Pfam PF13646 HEAT repeats 298 386 2.0E-6 T 23-10-2018 A3L04_04990 65d6de626852b69744bdd1133e2e4240 485 Gene3D G3DSA:1.25.10.10 273 484 7.1E-11 T 23-10-2018 IPR011989 Armadillo-like helical A3L04_06980 d7f7d3f8d8762df8ced592b71e570a46 189 Gene3D G3DSA:3.60.21.10 20 159 2.0E-9 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L04_06980 d7f7d3f8d8762df8ced592b71e570a46 189 SUPERFAMILY SSF56300 20 184 2.25E-15 T 23-10-2018 A3L04_06980 d7f7d3f8d8762df8ced592b71e570a46 189 Pfam PF00149 Calcineurin-like phosphoesterase 20 159 1.0E-9 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L04_08875 e0a50a0d74582af160eb38a255849d22 597 Gene3D G3DSA:3.20.110.20 45 318 1.1E-6 T 23-10-2018 A3L04_08875 e0a50a0d74582af160eb38a255849d22 597 SUPERFAMILY SSF88713 5 229 6.97E-20 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L04_00880 e1b08ee491ccfa1b669026c37b70820f 229 Gene3D G3DSA:3.30.420.440 1 229 7.6E-119 T 23-10-2018 A3L04_00880 e1b08ee491ccfa1b669026c37b70820f 229 Pfam PF13680 Protein of unknown function (DUF4152) 1 225 1.1E-125 T 23-10-2018 IPR025206 Protein of unknown function DUF4152 A3L04_08360 0980498b54a743b35ccc4062e59a50bb 329 SMART SM00382 45 248 1.8E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_08360 0980498b54a743b35ccc4062e59a50bb 329 Gene3D G3DSA:3.40.50.300 3 329 4.2E-101 T 23-10-2018 A3L04_08360 0980498b54a743b35ccc4062e59a50bb 329 Pfam PF00005 ABC transporter 37 189 5.7E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_08360 0980498b54a743b35ccc4062e59a50bb 329 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_08360 0980498b54a743b35ccc4062e59a50bb 329 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 325 3.7E-32 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L04_08360 0980498b54a743b35ccc4062e59a50bb 329 SUPERFAMILY SSF52540 5 260 8.18E-72 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_08360 0980498b54a743b35ccc4062e59a50bb 329 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 306 1.2E-21 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L04_10440 d112676d1e78163578998afc7c020244 189 PIRSF PIRSF006006 1 180 3.3E-88 T 23-10-2018 IPR007501 Protein of unknown function DUF531 A3L04_10440 d112676d1e78163578998afc7c020244 189 Pfam PF04407 Protein of unknown function (DUF531) 1 171 5.2E-76 T 23-10-2018 IPR007501 Protein of unknown function DUF531 A3L04_01990 9757ebe6c314fbdaae6b6d629ab75991 228 SUPERFAMILY SSF51735 1 145 2.94E-37 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_01990 9757ebe6c314fbdaae6b6d629ab75991 228 Pfam PF02080 TrkA-C domain 154 221 3.4E-13 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A3L04_01990 9757ebe6c314fbdaae6b6d629ab75991 228 Gene3D G3DSA:3.40.50.720 1 140 3.5E-41 T 23-10-2018 A3L04_01990 9757ebe6c314fbdaae6b6d629ab75991 228 SUPERFAMILY SSF116726 135 220 2.62E-13 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L04_01990 9757ebe6c314fbdaae6b6d629ab75991 228 Pfam PF02254 TrkA-N domain 3 123 2.8E-29 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A3L04_01990 9757ebe6c314fbdaae6b6d629ab75991 228 Gene3D G3DSA:3.30.70.1450 141 223 1.2E-16 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L04_01990 9757ebe6c314fbdaae6b6d629ab75991 228 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 1.9E-12 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L04_01990 9757ebe6c314fbdaae6b6d629ab75991 228 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 1.9E-12 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L04_01990 9757ebe6c314fbdaae6b6d629ab75991 228 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 1.9E-12 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L04_01990 9757ebe6c314fbdaae6b6d629ab75991 228 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 1.9E-12 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L04_01990 9757ebe6c314fbdaae6b6d629ab75991 228 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.9E-12 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L04_06675 f07300d3928edee14b718532946fea44 412 Gene3D G3DSA:3.30.1380.20 255 400 1.6E-6 T 23-10-2018 A3L04_06675 f07300d3928edee14b718532946fea44 412 SUPERFAMILY SSF111126 253 396 1.15E-20 T 23-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily A3L04_06675 f07300d3928edee14b718532946fea44 412 Gene3D G3DSA:3.40.50.300 1 224 3.2E-22 T 23-10-2018 A3L04_06675 f07300d3928edee14b718532946fea44 412 SUPERFAMILY SSF52540 3 201 1.53E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_06675 f07300d3928edee14b718532946fea44 412 SMART SM00989 335 397 2.2E-11 T 23-10-2018 IPR004096 4-vinyl reductase, 4VR A3L04_06675 f07300d3928edee14b718532946fea44 412 Pfam PF06745 KaiC 3 167 1.0E-12 T 23-10-2018 IPR014774 KaiC-like domain A3L04_06675 f07300d3928edee14b718532946fea44 412 Pfam PF02830 V4R domain 338 396 5.9E-11 T 23-10-2018 IPR004096 4-vinyl reductase, 4VR A3L04_08325 a8cf21122163fd3ade31c43f134e1282 344 TIGRFAM TIGR00322 diphth2_R: diphthamide biosynthesis enzyme Dph1/Dph2 domain 7 314 7.5E-90 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L04_08325 a8cf21122163fd3ade31c43f134e1282 344 Gene3D G3DSA:3.40.50.11860 213 314 8.9E-36 T 23-10-2018 A3L04_08325 a8cf21122163fd3ade31c43f134e1282 344 Pfam PF01866 Putative diphthamide synthesis protein 27 323 2.3E-75 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L04_08325 a8cf21122163fd3ade31c43f134e1282 344 PIRSF PIRSF004967 2 336 1.8E-80 T 23-10-2018 IPR035435 Diphthamide synthesis DHP1/DPH2, eukaryotes and archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L04_08325 a8cf21122163fd3ade31c43f134e1282 344 TIGRFAM TIGR03682 arCOG04112: diphthamide biosynthesis enzyme Dph2 18 325 1.4E-114 T 23-10-2018 IPR022428 Diphthamide synthesis Dph2, archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546 A3L04_08325 a8cf21122163fd3ade31c43f134e1282 344 Gene3D G3DSA:3.40.50.11850 101 209 5.8E-43 T 23-10-2018 A3L04_08325 a8cf21122163fd3ade31c43f134e1282 344 Gene3D G3DSA:3.40.50.11840 6 99 8.0E-30 T 23-10-2018 A3L04_06140 be1bac755eb2cc28ab56f286a13cd39d 152 Gene3D G3DSA:3.30.54.20 75 118 9.6E-24 T 23-10-2018 A3L04_06140 be1bac755eb2cc28ab56f286a13cd39d 152 SUPERFAMILY SSF55186 5 149 4.32E-36 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A3L04_06140 be1bac755eb2cc28ab56f286a13cd39d 152 Gene3D G3DSA:3.30.980.10 1 74 4.6E-31 T 23-10-2018 A3L04_01580 341b08d54cf1df2c2b50df0745aa11ba 393 Pfam PF01494 FAD binding domain 95 319 5.5E-15 T 23-10-2018 IPR002938 FAD-binding domain GO:0071949 A3L04_01580 341b08d54cf1df2c2b50df0745aa11ba 393 Pfam PF00890 FAD binding domain 4 46 8.5E-6 T 23-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L04_01580 341b08d54cf1df2c2b50df0745aa11ba 393 Gene3D G3DSA:3.50.50.60 3 338 5.2E-109 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_01580 341b08d54cf1df2c2b50df0745aa11ba 393 SUPERFAMILY SSF51905 1 344 1.58E-42 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_01580 341b08d54cf1df2c2b50df0745aa11ba 393 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 3 301 7.9E-77 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 A3L04_01580 341b08d54cf1df2c2b50df0745aa11ba 393 Gene3D G3DSA:3.30.9.10 69 357 5.2E-109 T 23-10-2018 A3L04_01580 341b08d54cf1df2c2b50df0745aa11ba 393 Hamap MF_01287 Digeranylgeranylglycerophospholipid reductase. 1 387 39.792 T 23-10-2018 IPR023590 Digeranylgeranylglycerophospholipid reductase GO:0016628|GO:0045550|GO:0046467|GO:0055114 KEGG: 00564+1.3.7.11|MetaCyc: PWY-6349 A3L04_01580 341b08d54cf1df2c2b50df0745aa11ba 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 8.0E-11 T 23-10-2018 A3L04_01580 341b08d54cf1df2c2b50df0745aa11ba 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 8.0E-11 T 23-10-2018 A3L04_01580 341b08d54cf1df2c2b50df0745aa11ba 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 266 281 8.0E-11 T 23-10-2018 A3L04_07370 9d48bce0c95724c6805aa06dce3a58ae 133 SMART SM00470 34 116 0.0024 T 23-10-2018 IPR003115 ParB/Sulfiredoxin A3L04_07370 9d48bce0c95724c6805aa06dce3a58ae 133 SUPERFAMILY SSF110849 36 117 8.24E-11 T 23-10-2018 IPR036086 ParB/Sulfiredoxin superfamily A3L04_07370 9d48bce0c95724c6805aa06dce3a58ae 133 Pfam PF02195 ParB-like nuclease domain 37 109 5.7E-8 T 23-10-2018 IPR003115 ParB/Sulfiredoxin A3L04_07370 9d48bce0c95724c6805aa06dce3a58ae 133 Gene3D G3DSA:3.90.1530.10 15 121 2.2E-7 T 23-10-2018 A3L04_02150 32ac113780af2ffec4e90fa69845d434 430 PRINTS PR00145 Argininosuccinate lyase family signature 135 155 1.1E-36 T 23-10-2018 A3L04_02150 32ac113780af2ffec4e90fa69845d434 430 PRINTS PR00145 Argininosuccinate lyase family signature 186 202 1.1E-36 T 23-10-2018 A3L04_02150 32ac113780af2ffec4e90fa69845d434 430 PRINTS PR00145 Argininosuccinate lyase family signature 264 280 1.1E-36 T 23-10-2018 A3L04_02150 32ac113780af2ffec4e90fa69845d434 430 PRINTS PR00145 Argininosuccinate lyase family signature 299 318 1.1E-36 T 23-10-2018 A3L04_02150 32ac113780af2ffec4e90fa69845d434 430 PRINTS PR00145 Argininosuccinate lyase family signature 94 116 1.1E-36 T 23-10-2018 A3L04_02150 32ac113780af2ffec4e90fa69845d434 430 PRINTS PR00145 Argininosuccinate lyase family signature 220 244 1.1E-36 T 23-10-2018 A3L04_02150 32ac113780af2ffec4e90fa69845d434 430 Pfam PF00206 Lyase 36 289 4.4E-43 T 23-10-2018 IPR022761 Fumarate lyase, N-terminal A3L04_02150 32ac113780af2ffec4e90fa69845d434 430 SUPERFAMILY SSF48557 8 389 1.54E-82 T 23-10-2018 IPR008948 L-Aspartase-like GO:0003824 A3L04_02150 32ac113780af2ffec4e90fa69845d434 430 Gene3D G3DSA:1.10.40.30 349 396 6.5E-102 T 23-10-2018 A3L04_02150 32ac113780af2ffec4e90fa69845d434 430 Hamap MF_00006 Argininosuccinate lyase [argH]. 1 430 29.628 T 23-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A3L04_02150 32ac113780af2ffec4e90fa69845d434 430 Gene3D G3DSA:1.20.200.10 112 348 6.5E-102 T 23-10-2018 A3L04_02150 32ac113780af2ffec4e90fa69845d434 430 TIGRFAM TIGR00838 argH: argininosuccinate lyase 9 389 1.4E-95 T 23-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A3L04_02150 32ac113780af2ffec4e90fa69845d434 430 Gene3D G3DSA:1.10.275.10 30 218 6.5E-102 T 23-10-2018 IPR024083 Fumarase/histidase, N-terminal A3L04_02150 32ac113780af2ffec4e90fa69845d434 430 PRINTS PR00149 Fumarate lyase superfamily signature 220 247 7.1E-18 T 23-10-2018 IPR000362 Fumarate lyase family A3L04_02150 32ac113780af2ffec4e90fa69845d434 430 PRINTS PR00149 Fumarate lyase superfamily signature 95 113 7.1E-18 T 23-10-2018 IPR000362 Fumarate lyase family A3L04_02150 32ac113780af2ffec4e90fa69845d434 430 PRINTS PR00149 Fumarate lyase superfamily signature 264 280 7.1E-18 T 23-10-2018 IPR000362 Fumarate lyase family A3L04_02150 32ac113780af2ffec4e90fa69845d434 430 PRINTS PR00149 Fumarate lyase superfamily signature 140 158 7.1E-18 T 23-10-2018 IPR000362 Fumarate lyase family A3L04_02220 ee33687ec8e219555f82964f63b61e7d 406 SUPERFAMILY SSF51366 2 211 9.06E-46 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L04_02220 ee33687ec8e219555f82964f63b61e7d 406 SUPERFAMILY SSF53697 215 404 2.22E-41 T 23-10-2018 A3L04_02220 ee33687ec8e219555f82964f63b61e7d 406 SMART SM00934 2 203 1.5E-45 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L04_02220 ee33687ec8e219555f82964f63b61e7d 406 Gene3D G3DSA:3.20.20.70 1 209 3.3E-76 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_02220 ee33687ec8e219555f82964f63b61e7d 406 Pfam PF01380 SIS domain 246 347 9.3E-22 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A3L04_02220 ee33687ec8e219555f82964f63b61e7d 406 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 3 203 7.2E-28 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L04_02220 ee33687ec8e219555f82964f63b61e7d 406 Gene3D G3DSA:3.40.50.10490 213 406 1.2E-59 T 23-10-2018 A3L04_02220 ee33687ec8e219555f82964f63b61e7d 406 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 3 206 2.1E-83 T 23-10-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 A3L04_02220 ee33687ec8e219555f82964f63b61e7d 406 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 219 406 1.9E-76 T 23-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 A3L04_01935 c392d20ca778e469cfc392aea91640cb 400 PIRSF PIRSF005572 15 400 2.4E-51 T 23-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 A3L04_01935 c392d20ca778e469cfc392aea91640cb 400 Gene3D G3DSA:3.90.1150.10 7 387 3.4E-149 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L04_01935 c392d20ca778e469cfc392aea91640cb 400 Pfam PF00266 Aminotransferase class-V 18 386 3.9E-143 T 23-10-2018 IPR000192 Aminotransferase class V domain A3L04_01935 c392d20ca778e469cfc392aea91640cb 400 SUPERFAMILY SSF53383 5 398 5.23E-121 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L04_01935 c392d20ca778e469cfc392aea91640cb 400 Gene3D G3DSA:3.40.640.10 29 287 3.4E-149 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L04_00615 3b30d994fa99129a0abd95c2f27941e6 193 SUPERFAMILY SSF81301 32 168 2.55E-7 T 23-10-2018 A3L04_00615 3b30d994fa99129a0abd95c2f27941e6 193 Gene3D G3DSA:3.30.460.40 6 166 9.6E-6 T 23-10-2018 A3L04_02520 f121261ae2a6da8368bc2bd47e22d068 212 SUPERFAMILY SSF56300 1 208 2.63E-72 T 23-10-2018 A3L04_02520 f121261ae2a6da8368bc2bd47e22d068 212 Gene3D G3DSA:3.60.21.10 1 212 5.2E-42 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L04_02520 f121261ae2a6da8368bc2bd47e22d068 212 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 202 1.8E-19 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L04_08220 4f2d3c5dea372ace875c237578381005 81 SUPERFAMILY SSF47598 5 47 2.0E-11 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A3L04_08220 4f2d3c5dea372ace875c237578381005 81 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 44 6.2E-10 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A3L04_08220 4f2d3c5dea372ace875c237578381005 81 Gene3D G3DSA:1.10.1220.10 1 61 2.1E-8 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A3L04_10320 e2a8484f1c7a62251120bfa80404988b 396 Pfam PF06819 Archaeal Peptidase A24 C-terminal Domain 254 361 2.9E-29 T 23-10-2018 IPR009639 Peptidase A24A-predicted, C-terminal archaea A3L04_10320 e2a8484f1c7a62251120bfa80404988b 396 Gene3D G3DSA:1.20.120.1220 53 173 1.3E-10 T 23-10-2018 A3L04_10170 a835e43af3ca2ff1b6fe87a345c40d0b 78 Pfam PF03683 Uncharacterised protein family (UPF0175) 15 73 4.3E-21 T 23-10-2018 IPR005368 Uncharacterised protein family UPF0175 A3L04_08125 f0e4631969905b0b40763dbc5b4d3c3a 171 Pfam PF02915 Rubrerythrin 10 124 5.5E-25 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L04_08125 f0e4631969905b0b40763dbc5b4d3c3a 171 Gene3D G3DSA:1.20.1260.10 2 132 2.6E-46 T 23-10-2018 IPR012347 Ferritin-like A3L04_08125 f0e4631969905b0b40763dbc5b4d3c3a 171 Gene3D G3DSA:2.20.28.10 133 171 3.1E-19 T 23-10-2018 A3L04_08125 f0e4631969905b0b40763dbc5b4d3c3a 171 SUPERFAMILY SSF47240 5 132 6.19E-37 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L04_08125 f0e4631969905b0b40763dbc5b4d3c3a 171 SUPERFAMILY SSF57802 137 170 3.2E-11 T 23-10-2018 A3L04_05615 a996c885f6a9fd3f3525b09d54448c19 239 SUPERFAMILY SSF48150 2 237 2.9E-87 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A3L04_05615 a996c885f6a9fd3f3525b09d54448c19 239 Gene3D G3DSA:1.10.1670.10 2 236 6.3E-93 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A3L04_05615 a996c885f6a9fd3f3525b09d54448c19 239 Gene3D G3DSA:1.10.340.30 22 166 6.3E-93 T 23-10-2018 A3L04_05615 a996c885f6a9fd3f3525b09d54448c19 239 Pfam PF09171 N-glycosylase/DNA lyase 4 223 1.5E-84 T 23-10-2018 IPR015254 N-glycosylase/DNA lyase-like GO:0003906|GO:0016799 A3L04_05615 a996c885f6a9fd3f3525b09d54448c19 239 Hamap MF_01168 N-glycosylase/DNA lyase. 1 234 40.733 T 23-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 A3L04_05615 a996c885f6a9fd3f3525b09d54448c19 239 PIRSF PIRSF008955 1 239 2.8E-103 T 23-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 A3L04_02405 5b4fbde892b8f37dbed74dc6d59856e2 745 SUPERFAMILY SSF82866 149 360 4.84E-42 T 23-10-2018 A3L04_02405 5b4fbde892b8f37dbed74dc6d59856e2 745 TIGRFAM TIGR00921 2A067: efflux transporter, putative, hydrophobe/amphiphile efflux-3 (HAE3) family 11 734 6.8E-278 T 23-10-2018 IPR004767 Hydrophobe/amphiphile efflux-3 HAE3 A3L04_02405 5b4fbde892b8f37dbed74dc6d59856e2 745 Gene3D G3DSA:1.20.1640.10 186 366 1.2E-22 T 23-10-2018 A3L04_02405 5b4fbde892b8f37dbed74dc6d59856e2 745 Gene3D G3DSA:1.20.1640.10 573 742 1.1E-11 T 23-10-2018 A3L04_02405 5b4fbde892b8f37dbed74dc6d59856e2 745 Pfam PF03176 MMPL family 45 359 1.0E-36 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A3L04_02405 5b4fbde892b8f37dbed74dc6d59856e2 745 Pfam PF03176 MMPL family 489 739 2.1E-30 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A3L04_02405 5b4fbde892b8f37dbed74dc6d59856e2 745 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 1.9E-5 T 23-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A3L04_02405 5b4fbde892b8f37dbed74dc6d59856e2 745 PRINTS PR00702 Acriflavin resistance protein family signature 204 227 1.9E-5 T 23-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A3L04_02405 5b4fbde892b8f37dbed74dc6d59856e2 745 SUPERFAMILY SSF82866 538 740 4.32E-36 T 23-10-2018 A3L04_06490 1c3305c674022cc15a346a0514ed8d23 215 Pfam PF08241 Methyltransferase domain 43 127 1.7E-20 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A3L04_06490 1c3305c674022cc15a346a0514ed8d23 215 Gene3D G3DSA:3.40.50.150 2 209 1.2E-62 T 23-10-2018 A3L04_06490 1c3305c674022cc15a346a0514ed8d23 215 SUPERFAMILY SSF53335 7 192 3.41E-34 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_08935 dd5d2ff0d7935f5e7fd3ed996f75ab0c 966 SUPERFAMILY SSF52374 4 694 5.63E-103 T 23-10-2018 A3L04_08935 dd5d2ff0d7935f5e7fd3ed996f75ab0c 966 SUPERFAMILY SSF47323 707 939 6.35E-39 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_08935 dd5d2ff0d7935f5e7fd3ed996f75ab0c 966 Gene3D G3DSA:1.10.730.10 690 809 6.8E-33 T 23-10-2018 A3L04_08935 dd5d2ff0d7935f5e7fd3ed996f75ab0c 966 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_08935 dd5d2ff0d7935f5e7fd3ed996f75ab0c 966 Gene3D G3DSA:3.30.2320.20 834 966 2.3E-48 T 23-10-2018 A3L04_08935 dd5d2ff0d7935f5e7fd3ed996f75ab0c 966 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 8 966 0.0 T 23-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L04_08935 dd5d2ff0d7935f5e7fd3ed996f75ab0c 966 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 12 689 3.9E-66 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_08935 dd5d2ff0d7935f5e7fd3ed996f75ab0c 966 Pfam PF08264 Anticodon-binding domain of tRNA 725 858 2.0E-30 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A3L04_08935 dd5d2ff0d7935f5e7fd3ed996f75ab0c 966 SUPERFAMILY SSF50677 210 443 5.97E-34 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L04_08935 dd5d2ff0d7935f5e7fd3ed996f75ab0c 966 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 6 966 18.461 T 23-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 A3L04_08935 dd5d2ff0d7935f5e7fd3ed996f75ab0c 966 Gene3D G3DSA:3.40.50.620 9 688 0.0 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_08935 dd5d2ff0d7935f5e7fd3ed996f75ab0c 966 Gene3D G3DSA:3.90.740.10 205 451 0.0 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L04_08935 dd5d2ff0d7935f5e7fd3ed996f75ab0c 966 Gene3D G3DSA:1.10.10.720 865 916 2.3E-48 T 23-10-2018 A3L04_06885 6d2ed0b990f16a7052f655656798069e 229 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 9 225 5.9E-84 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L04_06885 6d2ed0b990f16a7052f655656798069e 229 Pfam PF01902 Diphthamide synthase 9 225 8.9E-86 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L04_06885 6d2ed0b990f16a7052f655656798069e 229 PIRSF PIRSF039123 6 229 3.8E-79 T 23-10-2018 IPR030662 Diphthine--ammonia ligase/Uncharacterised protein MJ0570 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L04_06885 6d2ed0b990f16a7052f655656798069e 229 TIGRFAM TIGR00289 TIGR00289: TIGR00289 family protein 9 226 1.8E-89 T 23-10-2018 IPR005237 Uncharacterised protein MJ0570 A3L04_06885 6d2ed0b990f16a7052f655656798069e 229 Gene3D G3DSA:3.90.1490.10 144 229 1.6E-30 T 23-10-2018 A3L04_06885 6d2ed0b990f16a7052f655656798069e 229 Gene3D G3DSA:3.40.50.620 4 143 3.1E-51 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_06885 6d2ed0b990f16a7052f655656798069e 229 SUPERFAMILY SSF52402 9 227 1.6E-74 T 23-10-2018 A3L04_06885 6d2ed0b990f16a7052f655656798069e 229 TIGRFAM TIGR03679 arCOG00187: arCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein 10 224 5.9E-91 T 23-10-2018 IPR022427 Uncharacterised protein MJ0570, ATP-binding A3L04_09415 bc14799104cb695e5850b47f7ad4dfee 369 SUPERFAMILY SSF52540 3 279 1.18E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09415 bc14799104cb695e5850b47f7ad4dfee 369 Gene3D G3DSA:3.40.50.300 6 208 1.6E-46 T 23-10-2018 A3L04_09415 bc14799104cb695e5850b47f7ad4dfee 369 Pfam PF01637 ATPase domain predominantly from Archaea 16 249 1.0E-13 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_10305 24e5acdbcf729a0dbce5f0765aa89dbe 377 PIRSF PIRSF019435 1 377 4.0E-148 T 23-10-2018 IPR008508 Protein of unknown function DUF790, endonuclease-like A3L04_10305 24e5acdbcf729a0dbce5f0765aa89dbe 377 Pfam PF05626 Protein of unknown function (DUF790) 1 368 1.5E-126 T 23-10-2018 IPR008508 Protein of unknown function DUF790, endonuclease-like A3L04_01210 1ab684571469dd88efb7b49e679f1438 156 Gene3D G3DSA:3.30.2130.30 1 147 1.4E-11 T 23-10-2018 A3L04_01210 1ab684571469dd88efb7b49e679f1438 156 Pfam PF02926 THUMP domain 16 144 1.0E-18 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L04_01210 1ab684571469dd88efb7b49e679f1438 156 SMART SM00981 61 145 4.1E-11 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L04_01210 1ab684571469dd88efb7b49e679f1438 156 SUPERFAMILY SSF143437 42 145 2.27E-12 T 23-10-2018 A3L04_10250 99bcb3ac7573ad19b9e1bec3891cae11 185 Pfam PF01467 Cytidylyltransferase-like 4 134 2.5E-18 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L04_10250 99bcb3ac7573ad19b9e1bec3891cae11 185 SUPERFAMILY SSF52374 1 164 5.93E-38 T 23-10-2018 A3L04_10250 99bcb3ac7573ad19b9e1bec3891cae11 185 TIGRFAM TIGR01527 arch_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 2 166 1.4E-71 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 A3L04_10250 99bcb3ac7573ad19b9e1bec3891cae11 185 Gene3D G3DSA:3.40.50.620 1 175 1.3E-55 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_10250 99bcb3ac7573ad19b9e1bec3891cae11 185 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 185 92.282 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 A3L04_10250 99bcb3ac7573ad19b9e1bec3891cae11 185 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 2 61 2.2E-18 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L04_09650 0a8863a886fa6e66d1dad8e17dab41e6 329 TIGRFAM TIGR01177 TIGR01177: putative methyltransferase, TIGR01177 family 3 327 1.5E-111 T 23-10-2018 IPR005885 tRNA guanine(10)-N2-dimethyltransferase GO:0004809|GO:0030488 A3L04_09650 0a8863a886fa6e66d1dad8e17dab41e6 329 SMART SM00981 56 142 6.1E-4 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L04_09650 0a8863a886fa6e66d1dad8e17dab41e6 329 Pfam PF01170 Putative RNA methylase family UPF0020 157 304 1.7E-26 T 23-10-2018 IPR000241 Putative RNA methylase domain A3L04_09650 0a8863a886fa6e66d1dad8e17dab41e6 329 SUPERFAMILY SSF143437 33 134 4.19E-7 T 23-10-2018 A3L04_09650 0a8863a886fa6e66d1dad8e17dab41e6 329 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 252 258 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A3L04_09650 0a8863a886fa6e66d1dad8e17dab41e6 329 SUPERFAMILY SSF53335 140 292 5.63E-27 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_09650 0a8863a886fa6e66d1dad8e17dab41e6 329 Pfam PF02926 THUMP domain 60 141 5.6E-11 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L04_09650 0a8863a886fa6e66d1dad8e17dab41e6 329 Gene3D G3DSA:3.40.50.150 154 329 3.3E-32 T 23-10-2018 A3L04_00545 b86b950005c01014761f235927311c35 284 SUPERFAMILY SSF161098 5 277 7.72E-47 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_00545 b86b950005c01014761f235927311c35 284 Gene3D G3DSA:1.10.3720.10 1 277 2.2E-46 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_00545 b86b950005c01014761f235927311c35 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 271 1.8E-11 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L04_07170 f2f85781c6190c639c88d5f91c6f7977 153 Pfam PF01850 PIN domain 5 126 1.6E-8 T 23-10-2018 IPR002716 PIN domain A3L04_07170 f2f85781c6190c639c88d5f91c6f7977 153 Gene3D G3DSA:3.40.50.1010 3 129 1.1E-8 T 23-10-2018 A3L04_07170 f2f85781c6190c639c88d5f91c6f7977 153 SUPERFAMILY SSF88723 4 131 1.12E-12 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_00570 6b86b2ee00d03c443806c61dc17ae4cd 318 Gene3D G3DSA:3.90.25.10 223 317 1.3E-26 T 23-10-2018 A3L04_00570 6b86b2ee00d03c443806c61dc17ae4cd 318 Gene3D G3DSA:3.90.25.10 181 222 2.5E-12 T 23-10-2018 A3L04_00570 6b86b2ee00d03c443806c61dc17ae4cd 318 Gene3D G3DSA:3.40.50.720 1 180 3.6E-53 T 23-10-2018 A3L04_00570 6b86b2ee00d03c443806c61dc17ae4cd 318 SUPERFAMILY SSF51735 1 314 1.68E-87 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_00570 6b86b2ee00d03c443806c61dc17ae4cd 318 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 241 2.5E-57 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A3L04_03690 e1846ee334c05214a69d0e9ce1f149e8 336 Gene3D G3DSA:3.90.1150.10 19 329 1.5E-98 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L04_03690 e1846ee334c05214a69d0e9ce1f149e8 336 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 333 52.799 T 23-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A3L04_03690 e1846ee334c05214a69d0e9ce1f149e8 336 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 4 331 1.5E-97 T 23-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A3L04_03690 e1846ee334c05214a69d0e9ce1f149e8 336 Pfam PF00155 Aminotransferase class I and II 21 329 1.3E-52 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L04_03690 e1846ee334c05214a69d0e9ce1f149e8 336 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 202 211 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A3L04_03690 e1846ee334c05214a69d0e9ce1f149e8 336 Gene3D G3DSA:3.40.640.10 44 252 1.5E-98 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L04_03690 e1846ee334c05214a69d0e9ce1f149e8 336 SUPERFAMILY SSF53383 15 330 1.67E-77 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L04_07915 c33f60828e299766c1e641990a445831 71 ProSitePatterns PS00961 Ribosomal protein S28e signature. 59 67 - T 23-10-2018 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_07915 c33f60828e299766c1e641990a445831 71 SUPERFAMILY SSF50249 3 70 1.37E-26 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_07915 c33f60828e299766c1e641990a445831 71 Hamap MF_00292 30S ribosomal protein S28e [rps28e]. 1 68 25.691 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_07915 c33f60828e299766c1e641990a445831 71 Gene3D G3DSA:2.40.50.140 1 71 1.5E-35 T 23-10-2018 A3L04_07915 c33f60828e299766c1e641990a445831 71 Pfam PF01200 Ribosomal protein S28e 5 67 2.8E-30 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_07915 c33f60828e299766c1e641990a445831 71 ProDom PD005541 RIBOSOMAL RIBONUCLEOPROTEIN 40S S28 S28E 30S ACETYLATION S33 S33 CG15527 3 49 1.0E-16 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_01510 c97f93c7c0f8e1405fad0535b436655a 306 SMART SM00729 11 226 1.7E-14 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L04_01510 c97f93c7c0f8e1405fad0535b436655a 306 Pfam PF13353 4Fe-4S single cluster domain 18 116 7.5E-10 T 23-10-2018 A3L04_01510 c97f93c7c0f8e1405fad0535b436655a 306 Hamap MF_01225_A GTP 3',8-cyclase [moaA]. 2 306 44.722 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 A3L04_01510 c97f93c7c0f8e1405fad0535b436655a 306 TIGRFAM TIGR02668 moaA_archaeal: probable molybdenum cofactor biosynthesis protein A 2 306 5.3E-126 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 A3L04_01510 c97f93c7c0f8e1405fad0535b436655a 306 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 17 28 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L04_01510 c97f93c7c0f8e1405fad0535b436655a 306 Gene3D G3DSA:3.20.20.70 1 304 2.9E-80 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_01510 c97f93c7c0f8e1405fad0535b436655a 306 SUPERFAMILY SSF102114 2 301 5.36E-72 T 23-10-2018 A3L04_01510 c97f93c7c0f8e1405fad0535b436655a 306 Pfam PF06463 Molybdenum Cofactor Synthesis C 178 305 5.6E-22 T 23-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L04_01510 c97f93c7c0f8e1405fad0535b436655a 306 Pfam PF04055 Radical SAM superfamily 16 170 5.4E-37 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_06930 b0701a1b0914829e117cab318948698f 198 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 124 138 - T 23-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A3L04_06930 b0701a1b0914829e117cab318948698f 198 Pfam PF08241 Methyltransferase domain 40 134 3.3E-27 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A3L04_06930 b0701a1b0914829e117cab318948698f 198 Gene3D G3DSA:3.40.50.150 29 190 2.9E-36 T 23-10-2018 A3L04_06930 b0701a1b0914829e117cab318948698f 198 SUPERFAMILY SSF53335 4 179 9.34E-39 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_09900 11aecc5e3d7fcc442b1d2380b4664072 173 Gene3D G3DSA:1.10.260.40 75 173 4.3E-13 T 23-10-2018 A3L04_09900 11aecc5e3d7fcc442b1d2380b4664072 173 SUPERFAMILY SSF47413 76 140 1.07E-9 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L04_09900 11aecc5e3d7fcc442b1d2380b4664072 173 Pfam PF01381 Helix-turn-helix 89 139 9.1E-9 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L04_09900 11aecc5e3d7fcc442b1d2380b4664072 173 TIGRFAM TIGR00270 TIGR00270: TIGR00270 family protein 8 167 2.1E-30 T 23-10-2018 IPR004451 Conserved hypothetical protein CHP00270 A3L04_09900 11aecc5e3d7fcc442b1d2380b4664072 173 SMART SM00530 86 141 3.7E-9 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L04_03750 e75d489b490947681da1c578dbbca986 230 TIGRFAM TIGR00024 SbcD_rel_arch: putative phosphoesterase 5 221 2.7E-55 T 23-10-2018 IPR004376 Conserved hypothetical protein CHP00024, phosphoesterase-like A3L04_03750 e75d489b490947681da1c578dbbca986 230 SUPERFAMILY SSF56300 17 150 3.8E-15 T 23-10-2018 A3L04_03750 e75d489b490947681da1c578dbbca986 230 PIRSF PIRSF000887 5 225 3.5E-59 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 A3L04_03750 e75d489b490947681da1c578dbbca986 230 Gene3D G3DSA:3.60.21.10 16 149 2.2E-10 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L04_03750 e75d489b490947681da1c578dbbca986 230 Pfam PF00149 Calcineurin-like phosphoesterase 17 112 3.1E-6 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L04_07310 24cc032e05d3bb9be8086c11726c4aa0 398 Gene3D G3DSA:3.40.640.10 53 294 1.8E-149 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L04_07310 24cc032e05d3bb9be8086c11726c4aa0 398 SUPERFAMILY SSF53383 4 394 6.52E-111 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L04_07310 24cc032e05d3bb9be8086c11726c4aa0 398 Pfam PF00155 Aminotransferase class I and II 31 387 3.8E-60 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L04_07310 24cc032e05d3bb9be8086c11726c4aa0 398 Gene3D G3DSA:3.90.1150.10 25 390 1.8E-149 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L04_07690 6ddb1e9b6706c1ae4161a7541760102a 332 SUPERFAMILY SSF161098 97 319 9.55E-20 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_07690 6ddb1e9b6706c1ae4161a7541760102a 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 332 8.7E-44 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L04_05770 20aac390c514f217af1101ed5ebcd258 640 SMART SM00488 1 252 5.4E-101 T 23-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 A3L04_05770 20aac390c514f217af1101ed5ebcd258 640 SMART SM00491 459 602 2.7E-52 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A3L04_05770 20aac390c514f217af1101ed5ebcd258 640 TIGRFAM TIGR00604 rad3: DNA repair helicase (rad3) 3 629 7.0E-167 T 23-10-2018 IPR013020 ATP-dependent helicase Rad3/Chl1-like GO:0004003 A3L04_05770 20aac390c514f217af1101ed5ebcd258 640 SUPERFAMILY SSF52540 3 235 1.88E-15 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_05770 20aac390c514f217af1101ed5ebcd258 640 Gene3D G3DSA:3.40.50.300 412 618 3.7E-45 T 23-10-2018 A3L04_05770 20aac390c514f217af1101ed5ebcd258 640 Pfam PF06733 DEAD_2 62 233 2.0E-30 T 23-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 A3L04_05770 20aac390c514f217af1101ed5ebcd258 640 Gene3D G3DSA:3.40.50.300 18 397 1.6E-111 T 23-10-2018 A3L04_05770 20aac390c514f217af1101ed5ebcd258 640 Gene3D G3DSA:1.10.275.40 228 365 1.6E-111 T 23-10-2018 A3L04_05770 20aac390c514f217af1101ed5ebcd258 640 SUPERFAMILY SSF52540 27 599 1.95E-8 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_05770 20aac390c514f217af1101ed5ebcd258 640 Pfam PF13307 Helicase C-terminal domain 442 615 4.1E-38 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A3L04_05770 20aac390c514f217af1101ed5ebcd258 640 SMART SM00487 6 264 3.3E-10 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L04_05770 20aac390c514f217af1101ed5ebcd258 640 Gene3D G3DSA:1.10.30.20 93 169 1.6E-111 T 23-10-2018 A3L04_05770 20aac390c514f217af1101ed5ebcd258 640 Pfam PF06777 Helical and beta-bridge domain 238 428 9.0E-69 T 23-10-2018 IPR010643 Helical and beta-bridge domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-2564830|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 A3L04_06825 36eb68f8260331bd91d8f7d5f545897a 83 SUPERFAMILY SSF50104 2 80 1.14E-21 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L04_06825 36eb68f8260331bd91d8f7d5f545897a 83 Gene3D G3DSA:2.30.30.30 2 82 1.9E-31 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L04_06825 36eb68f8260331bd91d8f7d5f545897a 83 Pfam PF01929 Ribosomal protein L14 44 80 7.7E-5 T 23-10-2018 IPR002784 Ribosomal protein L14e domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_06825 36eb68f8260331bd91d8f7d5f545897a 83 Hamap MF_00721 50S ribosomal protein L14e [rpl14e]. 1 79 28.275 T 23-10-2018 IPR023651 Ribosomal protein L14e GO:0003735|GO:0005840|GO:0006412 A3L04_10205 70aa8549fce0284427bce8c1aaa1c3aa 126 SUPERFAMILY SSF88723 2 122 1.91E-24 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_10205 70aa8549fce0284427bce8c1aaa1c3aa 126 Pfam PF01850 PIN domain 4 113 8.6E-12 T 23-10-2018 IPR002716 PIN domain A3L04_10205 70aa8549fce0284427bce8c1aaa1c3aa 126 Gene3D G3DSA:3.40.50.1010 2 125 1.9E-21 T 23-10-2018 A3L04_06075 772b6c939713c4ad33f48781af768700 75 Gene3D G3DSA:3.30.70.920 1 74 3.4E-28 T 23-10-2018 A3L04_06075 772b6c939713c4ad33f48781af768700 75 Pfam PF01037 Lrp/AsnC ligand binding domain 9 74 2.2E-19 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L04_06075 772b6c939713c4ad33f48781af768700 75 SUPERFAMILY SSF54909 1 74 1.74E-18 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L04_03260 ab05e40d98d6b3efa9d976e58c8276ab 224 TIGRFAM TIGR00659 TIGR00659: TIGR00659 family protein 4 222 5.6E-86 T 23-10-2018 IPR005261 Conserved hypothetical protein CHP00659 A3L04_03260 ab05e40d98d6b3efa9d976e58c8276ab 224 Pfam PF04172 LrgB-like family 9 221 3.9E-77 T 23-10-2018 IPR007300 CidB/LrgB family A3L04_00985 b4e5fa9997e12d48d887692cd256ec5b 233 Pfam PF03099 Biotin/lipoate A/B protein ligase family 97 185 1.1E-6 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A3L04_00985 b4e5fa9997e12d48d887692cd256ec5b 233 Gene3D G3DSA:1.10.10.10 6 64 9.5E-15 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_00985 b4e5fa9997e12d48d887692cd256ec5b 233 Gene3D G3DSA:3.30.930.10 70 232 5.8E-24 T 23-10-2018 A3L04_00985 b4e5fa9997e12d48d887692cd256ec5b 233 SUPERFAMILY SSF46785 9 61 2.28E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_00985 b4e5fa9997e12d48d887692cd256ec5b 233 SUPERFAMILY SSF55681 69 227 1.37E-24 T 23-10-2018 A3L04_00985 b4e5fa9997e12d48d887692cd256ec5b 233 Pfam PF08279 HTH domain 11 59 2.9E-11 T 23-10-2018 IPR013196 Helix-turn-helix, type 11 A3L04_06095 975e936f817c6435997771182abef868 115 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 7 112 5.2E-23 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A3L04_06095 975e936f817c6435997771182abef868 115 Gene3D G3DSA:3.30.479.10 1 115 6.4E-38 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 A3L04_06095 975e936f817c6435997771182abef868 115 PIRSF PIRSF006113 1 115 5.2E-36 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A3L04_06095 975e936f817c6435997771182abef868 115 SUPERFAMILY SSF55620 2 112 9.45E-30 T 23-10-2018 A3L04_00280 d6714cce938c13a56c53697c2ecfae15 413 Gene3D G3DSA:3.50.50.60 5 296 2.9E-51 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_00280 d6714cce938c13a56c53697c2ecfae15 413 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.1E-23 T 23-10-2018 A3L04_00280 d6714cce938c13a56c53697c2ecfae15 413 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 1.1E-23 T 23-10-2018 A3L04_00280 d6714cce938c13a56c53697c2ecfae15 413 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 110 128 1.1E-23 T 23-10-2018 A3L04_00280 d6714cce938c13a56c53697c2ecfae15 413 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 247 263 1.1E-23 T 23-10-2018 A3L04_00280 d6714cce938c13a56c53697c2ecfae15 413 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 1.1E-23 T 23-10-2018 A3L04_00280 d6714cce938c13a56c53697c2ecfae15 413 Gene3D G3DSA:3.50.50.60 122 255 2.9E-51 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_00280 d6714cce938c13a56c53697c2ecfae15 413 SUPERFAMILY SSF51905 5 330 2.95E-40 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_00280 d6714cce938c13a56c53697c2ecfae15 413 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 1.3E-17 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L04_00280 d6714cce938c13a56c53697c2ecfae15 413 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 205 221 1.3E-17 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L04_00280 d6714cce938c13a56c53697c2ecfae15 413 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 111 119 1.3E-17 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L04_00280 d6714cce938c13a56c53697c2ecfae15 413 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 1.3E-17 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L04_00280 d6714cce938c13a56c53697c2ecfae15 413 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 153 177 1.3E-17 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L04_00280 d6714cce938c13a56c53697c2ecfae15 413 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 285 303 1.3E-17 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L04_00280 d6714cce938c13a56c53697c2ecfae15 413 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 296 5.8E-29 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L04_02500 6b94bd171b13e69732aea6fd098034ca 310 Pfam PF01171 PP-loop family 49 218 1.8E-11 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A3L04_02500 6b94bd171b13e69732aea6fd098034ca 310 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 190 289 1.2E-25 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 A3L04_02500 6b94bd171b13e69732aea6fd098034ca 310 SUPERFAMILY SSF52402 24 243 6.84E-50 T 23-10-2018 A3L04_02500 6b94bd171b13e69732aea6fd098034ca 310 Gene3D G3DSA:3.40.50.620 1 309 2.5E-93 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_02500 6b94bd171b13e69732aea6fd098034ca 310 PIRSF PIRSF004976 1 299 1.6E-95 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 A3L04_04440 f327b65bb690cd1b4182ead0fc305ac8 185 Pfam PF01944 Stage II sporulation protein M 12 179 3.4E-33 T 23-10-2018 IPR002798 Stage II sporulation protein M-like A3L04_00325 0d1c2fb0b767c51b67b61bbbbebf39f3 141 Pfam PF01850 PIN domain 9 133 1.8E-16 T 23-10-2018 IPR002716 PIN domain A3L04_00325 0d1c2fb0b767c51b67b61bbbbebf39f3 141 SUPERFAMILY SSF88723 9 139 1.15E-27 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_00325 0d1c2fb0b767c51b67b61bbbbebf39f3 141 Gene3D G3DSA:3.40.50.1010 9 140 6.2E-29 T 23-10-2018 A3L04_00325 0d1c2fb0b767c51b67b61bbbbebf39f3 141 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 9 140 10.052 T 23-10-2018 IPR022907 VapC family GO:0004540 A3L04_01555 acc0bd65f0af05927689568a48ef3104 479 Gene3D G3DSA:3.40.50.300 5 157 4.2E-37 T 23-10-2018 A3L04_01555 acc0bd65f0af05927689568a48ef3104 479 SMART SM00382 42 160 6.2E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_01555 acc0bd65f0af05927689568a48ef3104 479 SUPERFAMILY SSF52540 4 222 4.67E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01555 acc0bd65f0af05927689568a48ef3104 479 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 46 153 8.9E-16 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L04_01555 acc0bd65f0af05927689568a48ef3104 479 Gene3D G3DSA:1.10.8.60 161 224 2.4E-10 T 23-10-2018 A3L04_01555 acc0bd65f0af05927689568a48ef3104 479 Hamap MF_01508 Replication factor C large subunit [rfcL]. 4 433 35.395 T 23-10-2018 IPR023935 Replication factor C, large subunit A3L04_05665 6854b96e5610a9f955831d6ce323d293 230 SUPERFAMILY SSF143555 13 181 3.53E-50 T 23-10-2018 A3L04_05665 6854b96e5610a9f955831d6ce323d293 230 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 179 213 1.5E-7 T 23-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 A3L04_05665 6854b96e5610a9f955831d6ce323d293 230 PIRSF PIRSF006578 3 215 1.3E-50 T 23-10-2018 IPR026328 Formylmethanofuran dehydrogenase, subunit E A3L04_05665 6854b96e5610a9f955831d6ce323d293 230 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 23 163 9.4E-37 T 23-10-2018 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain A3L04_05665 6854b96e5610a9f955831d6ce323d293 230 Gene3D G3DSA:3.30.1330.130 3 174 1.4E-42 T 23-10-2018 A3L04_09120 cde1e1846803a10b155cd33ba8935968 126 Gene3D G3DSA:3.30.70.120 1 126 4.8E-58 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A3L04_09120 cde1e1846803a10b155cd33ba8935968 126 Pfam PF02641 Uncharacterized ACR, COG1993 11 104 7.6E-39 T 23-10-2018 IPR003793 Domain of unknown function DUF190 A3L04_09120 cde1e1846803a10b155cd33ba8935968 126 SUPERFAMILY SSF54913 8 104 2.71E-33 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A3L04_02960 c1699a506787c9bb5cd97bf7fae4d1c5 268 Pfam PF00005 ABC transporter 18 160 1.1E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_02960 c1699a506787c9bb5cd97bf7fae4d1c5 268 SUPERFAMILY SSF52540 4 223 2.54E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_02960 c1699a506787c9bb5cd97bf7fae4d1c5 268 Gene3D G3DSA:3.40.50.300 4 244 2.1E-67 T 23-10-2018 A3L04_02960 c1699a506787c9bb5cd97bf7fae4d1c5 268 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_02960 c1699a506787c9bb5cd97bf7fae4d1c5 268 SMART SM00382 27 210 2.4E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_08775 96550350399ac906653b7adb26654075 661 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 53 68 6.3E-9 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_08775 96550350399ac906653b7adb26654075 661 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 6.3E-9 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_08775 96550350399ac906653b7adb26654075 661 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 6.3E-9 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_08775 96550350399ac906653b7adb26654075 661 Pfam PF07670 Nucleoside recognition 353 447 5.6E-14 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A3L04_08775 96550350399ac906653b7adb26654075 661 Pfam PF07670 Nucleoside recognition 514 634 4.9E-28 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A3L04_08775 96550350399ac906653b7adb26654075 661 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 9 630 2.0E-187 T 23-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 A3L04_08775 96550350399ac906653b7adb26654075 661 SUPERFAMILY SSF52540 4 173 1.77E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_08775 96550350399ac906653b7adb26654075 661 Pfam PF02421 Ferrous iron transport protein B 4 157 4.0E-65 T 23-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 A3L04_08775 96550350399ac906653b7adb26654075 661 Pfam PF07664 Ferrous iron transport protein B C terminus 458 509 7.0E-20 T 23-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 A3L04_08775 96550350399ac906653b7adb26654075 661 Gene3D G3DSA:3.40.50.300 1 169 7.2E-50 T 23-10-2018 A3L04_03760 c25f7ae4045562dd2a1d5ced9e960c1f 227 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 220 1.5E-54 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L04_03760 c25f7ae4045562dd2a1d5ced9e960c1f 227 SUPERFAMILY SSF53681 102 211 3.49E-25 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L04_03760 c25f7ae4045562dd2a1d5ced9e960c1f 227 Gene3D G3DSA:3.40.50.1860 4 215 3.7E-78 T 23-10-2018 A3L04_03760 c25f7ae4045562dd2a1d5ced9e960c1f 227 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 224 1.8E-55 T 23-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 A3L04_03760 c25f7ae4045562dd2a1d5ced9e960c1f 227 Gene3D G3DSA:3.40.50.1860 102 211 3.7E-78 T 23-10-2018 A3L04_03760 c25f7ae4045562dd2a1d5ced9e960c1f 227 SUPERFAMILY SSF53681 1 114 6.54E-29 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L04_07670 f26a1c2b446b7657eebaffebe6fe2987 125 Pfam PF06146 Phosphate-starvation-inducible E 48 112 2.3E-14 T 23-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like A3L04_09750 69e24eca0d535437295872dda1f4de73 246 Gene3D G3DSA:3.40.50.300 2 244 4.1E-76 T 23-10-2018 A3L04_09750 69e24eca0d535437295872dda1f4de73 246 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 4 242 1.2E-108 T 23-10-2018 IPR010224 ATP binding protein MinD, archaea A3L04_09750 69e24eca0d535437295872dda1f4de73 246 Pfam PF13614 AAA domain 3 147 1.0E-27 T 23-10-2018 IPR025669 AAA domain A3L04_09750 69e24eca0d535437295872dda1f4de73 246 PIRSF PIRSF003092 1 243 3.3E-55 T 23-10-2018 IPR025501 ATP binding protein MinD A3L04_09750 69e24eca0d535437295872dda1f4de73 246 SUPERFAMILY SSF52540 3 236 2.78E-62 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_03150 d0efd39aab862d01a4f2c48bcd7f2a70 260 Pfam PF05763 Protein of unknown function (DUF835) 137 254 7.3E-33 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L04_04865 6d480d6d957614507aa092efabf4dc89 218 Gene3D G3DSA:3.40.50.1860 4 204 7.0E-82 T 23-10-2018 A3L04_04865 6d480d6d957614507aa092efabf4dc89 218 Gene3D G3DSA:3.40.50.1860 100 199 7.0E-82 T 23-10-2018 A3L04_04865 6d480d6d957614507aa092efabf4dc89 218 Pfam PF01177 Asp/Glu/Hydantoin racemase 39 200 2.2E-11 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L04_07555 8fe407bd6eadd6e696d8826227c7577f 427 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 234 400 2.1E-38 T 23-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 A3L04_07555 8fe407bd6eadd6e696d8826227c7577f 427 SUPERFAMILY SSF52402 209 389 1.23E-35 T 23-10-2018 A3L04_07555 8fe407bd6eadd6e696d8826227c7577f 427 Gene3D G3DSA:3.40.50.620 196 397 1.6E-37 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_00155 e5912fbc1e2c9c6940ee9b5c52ea49be 217 SUPERFAMILY SSF53335 1 213 3.75E-58 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_00155 e5912fbc1e2c9c6940ee9b5c52ea49be 217 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 2 215 41.261 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A3L04_00155 e5912fbc1e2c9c6940ee9b5c52ea49be 217 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 10 211 1.2E-69 T 23-10-2018 A3L04_00155 e5912fbc1e2c9c6940ee9b5c52ea49be 217 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 9 212 8.6E-64 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A3L04_00155 e5912fbc1e2c9c6940ee9b5c52ea49be 217 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 134 149 - T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A3L04_00155 e5912fbc1e2c9c6940ee9b5c52ea49be 217 Gene3D G3DSA:3.40.50.150 1 217 3.3E-97 T 23-10-2018 A3L04_03560 01b805bad83ebf0ca7af4aa04206f6a1 217 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 189 2.7E-27 T 23-10-2018 A3L04_03560 01b805bad83ebf0ca7af4aa04206f6a1 217 SUPERFAMILY SSF56784 1 214 1.13E-44 T 23-10-2018 IPR036412 HAD-like superfamily A3L04_03560 01b805bad83ebf0ca7af4aa04206f6a1 217 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 91 184 3.1E-10 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_03560 01b805bad83ebf0ca7af4aa04206f6a1 217 Gene3D G3DSA:1.10.150.240 15 89 3.5E-33 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A3L04_03560 01b805bad83ebf0ca7af4aa04206f6a1 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 179 192 8.6E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_03560 01b805bad83ebf0ca7af4aa04206f6a1 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 8.6E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_03560 01b805bad83ebf0ca7af4aa04206f6a1 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 152 172 8.6E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_03560 01b805bad83ebf0ca7af4aa04206f6a1 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 101 114 8.6E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_03560 01b805bad83ebf0ca7af4aa04206f6a1 217 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 82 189 9.6E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_03560 01b805bad83ebf0ca7af4aa04206f6a1 217 Gene3D G3DSA:3.40.50.1000 3 203 3.5E-33 T 23-10-2018 IPR023214 HAD superfamily A3L04_02980 d0c25b3b6da40e61ce5c76d9517a28ed 253 Gene3D G3DSA:3.40.50.150 63 253 4.1E-63 T 23-10-2018 A3L04_02980 d0c25b3b6da40e61ce5c76d9517a28ed 253 SUPERFAMILY SSF53335 1 253 1.19E-71 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_02980 d0c25b3b6da40e61ce5c76d9517a28ed 253 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 74 232 5.2E-27 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 A3L04_02980 d0c25b3b6da40e61ce5c76d9517a28ed 253 PIRSF PIRSF017269 1 253 3.0E-72 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 A3L04_02980 d0c25b3b6da40e61ce5c76d9517a28ed 253 Gene3D G3DSA:3.10.330.20 1 62 1.4E-23 T 23-10-2018 A3L04_02980 d0c25b3b6da40e61ce5c76d9517a28ed 253 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 2 43 6.7E-7 T 23-10-2018 A3L04_09280 0b29b54d050acc2581972da14306801b 326 SMART SM00382 20 191 9.8E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_09280 0b29b54d050acc2581972da14306801b 326 Pfam PF01637 ATPase domain predominantly from Archaea 2 233 1.7E-57 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_09280 0b29b54d050acc2581972da14306801b 326 ProDom PD003808 ATP-BINDING NUCLEOTIDE-BINDING PLASMID MJ0801 MJ0147 PYRAB06260 MJ0632 PYRAB09480 MJ0819 MJ1076 244 322 2.0E-4 T 23-10-2018 A3L04_09280 0b29b54d050acc2581972da14306801b 326 SUPERFAMILY SSF52540 1 248 4.57E-28 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09280 0b29b54d050acc2581972da14306801b 326 Gene3D G3DSA:3.40.50.300 1 194 4.5E-23 T 23-10-2018 A3L04_08780 2e56627ade89244e108ad481218104f9 80 Pfam PF09012 FeoC like transcriptional regulator 7 57 3.0E-8 T 23-10-2018 IPR015102 Transcriptional regulator HTH-type, FeoC A3L04_08780 2e56627ade89244e108ad481218104f9 80 SUPERFAMILY SSF46785 4 66 7.44E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_08780 2e56627ade89244e108ad481218104f9 80 Gene3D G3DSA:1.10.10.10 4 53 1.4E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_01710 2ad6a66afe1f57f55b2f4ef10c34578f 341 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 77 1.7E-24 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L04_01710 2ad6a66afe1f57f55b2f4ef10c34578f 341 SUPERFAMILY SSF159071 256 340 9.15E-19 T 23-10-2018 A3L04_01710 2ad6a66afe1f57f55b2f4ef10c34578f 341 Pfam PF11495 Archaeal transcriptional regulator TrmB 112 340 2.1E-56 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal A3L04_01710 2ad6a66afe1f57f55b2f4ef10c34578f 341 Gene3D G3DSA:1.10.10.10 1 103 5.1E-30 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_01710 2ad6a66afe1f57f55b2f4ef10c34578f 341 SUPERFAMILY SSF46785 2 98 8.49E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_03220 71fe41e3af234e025e975ef30a1b6f96 312 SMART SM00530 127 182 1.3E-13 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L04_03220 71fe41e3af234e025e975ef30a1b6f96 312 Gene3D G3DSA:1.10.260.40 121 223 4.9E-13 T 23-10-2018 A3L04_03220 71fe41e3af234e025e975ef30a1b6f96 312 Pfam PF01381 Helix-turn-helix 128 179 3.4E-13 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L04_03220 71fe41e3af234e025e975ef30a1b6f96 312 Hamap MF_00584 Putative HTH-type transcriptional regulatory protein . 1 300 29.266 T 23-10-2018 IPR020886 Transcription regulator HTH, Cro/C1-type DNA-binding GO:0003700|GO:0006355 A3L04_03220 71fe41e3af234e025e975ef30a1b6f96 312 SUPERFAMILY SSF47413 123 179 2.12E-13 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L04_05405 89b0e861753352e1ee8c4a457deec8a8 482 SUPERFAMILY SSF55681 9 279 9.19E-77 T 23-10-2018 A3L04_05405 89b0e861753352e1ee8c4a457deec8a8 482 SUPERFAMILY SSF52954 281 405 2.11E-39 T 23-10-2018 A3L04_05405 89b0e861753352e1ee8c4a457deec8a8 482 Pfam PF03129 Anticodon binding domain 292 385 3.6E-26 T 23-10-2018 IPR004154 Anticodon-binding A3L04_05405 89b0e861753352e1ee8c4a457deec8a8 482 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 98 274 1.5E-22 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_05405 89b0e861753352e1ee8c4a457deec8a8 482 SMART SM00946 413 482 4.5E-28 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L04_05405 89b0e861753352e1ee8c4a457deec8a8 482 PRINTS PR01046 Prolyl-tRNA synthetase signature 138 146 4.2E-7 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A3L04_05405 89b0e861753352e1ee8c4a457deec8a8 482 PRINTS PR01046 Prolyl-tRNA synthetase signature 63 81 4.2E-7 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A3L04_05405 89b0e861753352e1ee8c4a457deec8a8 482 PRINTS PR01046 Prolyl-tRNA synthetase signature 148 159 4.2E-7 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A3L04_05405 89b0e861753352e1ee8c4a457deec8a8 482 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 8 482 9.5E-178 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L04_05405 89b0e861753352e1ee8c4a457deec8a8 482 Gene3D G3DSA:3.30.930.10 10 285 7.5E-85 T 23-10-2018 A3L04_05405 89b0e861753352e1ee8c4a457deec8a8 482 Gene3D G3DSA:3.40.50.800 286 404 4.8E-40 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A3L04_05405 89b0e861753352e1ee8c4a457deec8a8 482 SUPERFAMILY SSF64586 408 482 5.89E-22 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L04_05405 89b0e861753352e1ee8c4a457deec8a8 482 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 414 482 4.5E-18 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L04_05405 89b0e861753352e1ee8c4a457deec8a8 482 Hamap MF_01571 Proline--tRNA ligase [proS]. 4 482 40.205 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L04_05405 89b0e861753352e1ee8c4a457deec8a8 482 Gene3D G3DSA:3.30.110.30 407 481 3.0E-20 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L04_00840 92ce41c44aab59fac21dd3a2dcb931ba 148 SUPERFAMILY SSF46785 3 64 8.69E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_00840 92ce41c44aab59fac21dd3a2dcb931ba 148 Gene3D G3DSA:3.30.70.920 56 148 6.6E-37 T 23-10-2018 A3L04_00840 92ce41c44aab59fac21dd3a2dcb931ba 148 SUPERFAMILY SSF54909 65 142 8.22E-6 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L04_00840 92ce41c44aab59fac21dd3a2dcb931ba 148 Gene3D G3DSA:1.10.10.10 1 55 8.0E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_00840 92ce41c44aab59fac21dd3a2dcb931ba 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 3.3E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_00840 92ce41c44aab59fac21dd3a2dcb931ba 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 3.3E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_00840 92ce41c44aab59fac21dd3a2dcb931ba 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 3.3E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_00840 92ce41c44aab59fac21dd3a2dcb931ba 148 SMART SM00344 4 110 1.6E-24 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L04_00840 92ce41c44aab59fac21dd3a2dcb931ba 148 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 51 1.7E-13 T 23-10-2018 A3L04_06795 86954b0947b03a0d07915d05418e5f9d 619 Gene3D G3DSA:1.10.599.10 237 605 1.7E-133 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A3L04_06795 86954b0947b03a0d07915d05418e5f9d 619 SUPERFAMILY SSF56228 1 209 2.88E-75 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L04_06795 86954b0947b03a0d07915d05418e5f9d 619 Gene3D G3DSA:1.10.569.10 239 417 1.7E-133 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L04_06795 86954b0947b03a0d07915d05418e5f9d 619 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 204 2.6E-79 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L04_06795 86954b0947b03a0d07915d05418e5f9d 619 SMART SM00790 4 205 7.1E-123 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L04_06795 86954b0947b03a0d07915d05418e5f9d 619 SUPERFAMILY SSF48310 211 618 6.28E-126 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L04_06795 86954b0947b03a0d07915d05418e5f9d 619 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 218 605 8.9E-110 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L04_06795 86954b0947b03a0d07915d05418e5f9d 619 Gene3D G3DSA:3.60.9.10 1 209 1.9E-92 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L04_03815 b7521ff26bac3b0e6776002a50d99dea 326 TIGRFAM TIGR01902 dapE-lys-deAc: N-acetyl-ornithine/N-acetyl-lysine deacetylase 9 323 2.6E-121 T 23-10-2018 IPR010175 [LysW]-lysine/[LysW]-ornithine hydrolase GO:0005737|GO:0008270|GO:0009085|GO:0016811|GO:0050897 A3L04_03815 b7521ff26bac3b0e6776002a50d99dea 326 PIRSF PIRSF001123 100 137 190.0 T 23-10-2018 IPR008007 Peptidase M42 A3L04_03815 b7521ff26bac3b0e6776002a50d99dea 326 PIRSF PIRSF001123 4 84 3.7E-14 T 23-10-2018 IPR008007 Peptidase M42 A3L04_03815 b7521ff26bac3b0e6776002a50d99dea 326 PIRSF PIRSF001123 265 326 16.0 T 23-10-2018 IPR008007 Peptidase M42 A3L04_03815 b7521ff26bac3b0e6776002a50d99dea 326 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 61 70 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A3L04_03815 b7521ff26bac3b0e6776002a50d99dea 326 Pfam PF01546 Peptidase family M20/M25/M40 62 320 1.4E-23 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A3L04_03815 b7521ff26bac3b0e6776002a50d99dea 326 SUPERFAMILY SSF53187 5 322 1.2E-47 T 23-10-2018 A3L04_03815 b7521ff26bac3b0e6776002a50d99dea 326 Gene3D G3DSA:3.40.630.10 15 313 1.1E-75 T 23-10-2018 A3L04_03815 b7521ff26bac3b0e6776002a50d99dea 326 Hamap MF_01120 [LysW]-lysine/[LysW]-ornithine hydrolase [lysK]. 5 323 31.258 T 23-10-2018 IPR010175 [LysW]-lysine/[LysW]-ornithine hydrolase GO:0005737|GO:0008270|GO:0009085|GO:0016811|GO:0050897 A3L04_03815 b7521ff26bac3b0e6776002a50d99dea 326 Gene3D G3DSA:3.30.70.360 151 237 1.1E-75 T 23-10-2018 A3L04_02675 8417c700945f51c125a2958db663e329 569 Gene3D G3DSA:3.40.50.300 1 216 2.0E-21 T 23-10-2018 A3L04_02675 8417c700945f51c125a2958db663e329 569 Pfam PF14907 Uncharacterised nucleotidyltransferase 248 485 2.6E-17 T 23-10-2018 IPR039498 Uncharacterised nucleotidyltransferase A3L04_02675 8417c700945f51c125a2958db663e329 569 Pfam PF02224 Cytidylate kinase 3 34 2.3E-4 T 23-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A3L04_02675 8417c700945f51c125a2958db663e329 569 SUPERFAMILY SSF52540 1 225 2.5E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_08905 94b6d37ed4d57354681cc4bfc25ea99e 194 Gene3D G3DSA:3.40.1120.10 1 193 1.5E-90 T 23-10-2018 IPR024794 Ribosomal protein L15e core domain superfamily GO:0003735|GO:0005840 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_08905 94b6d37ed4d57354681cc4bfc25ea99e 194 ProSitePatterns PS01194 Ribosomal protein L15e signature. 46 69 - T 23-10-2018 IPR020925 Ribosomal protein L15e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_08905 94b6d37ed4d57354681cc4bfc25ea99e 194 SMART SM01384 2 191 7.1E-134 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_08905 94b6d37ed4d57354681cc4bfc25ea99e 194 SUPERFAMILY SSF54189 1 191 3.79E-87 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_08905 94b6d37ed4d57354681cc4bfc25ea99e 194 Pfam PF00827 Ribosomal L15 2 189 6.5E-90 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_08905 94b6d37ed4d57354681cc4bfc25ea99e 194 Hamap MF_00256 50S ribosomal protein L15e [rpl15e]. 1 193 43.781 T 23-10-2018 IPR020926 Ribosomal protein L15e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_06975 ed0112bda1f8150b4665095a0eed7f66 225 Hamap MF_00554 Ribosomal RNA small subunit methyltransferase Nep1 [nep1]. 6 220 41.449 T 23-10-2018 IPR023503 Ribosome biogenesis methyltransferase NEP1, archaea GO:0008168 A3L04_06975 ed0112bda1f8150b4665095a0eed7f66 225 SUPERFAMILY SSF75217 6 219 1.7E-63 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L04_06975 ed0112bda1f8150b4665095a0eed7f66 225 Gene3D G3DSA:3.40.1280.10 5 225 2.9E-77 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L04_06975 ed0112bda1f8150b4665095a0eed7f66 225 Pfam PF03587 EMG1/NEP1 methyltransferase 9 219 1.3E-51 T 23-10-2018 IPR005304 Ribosomal biogenesis, methyltransferase, EMG1/NEP1 GO:0008168 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A3L04_02115 fbed101bcdecce56a08ba6c662c2ae75 223 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 221 6.0E-51 T 23-10-2018 A3L04_02115 fbed101bcdecce56a08ba6c662c2ae75 223 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 2 219 45.13 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L04_02115 fbed101bcdecce56a08ba6c662c2ae75 223 SUPERFAMILY SSF52317 2 221 1.2E-77 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L04_02115 fbed101bcdecce56a08ba6c662c2ae75 223 Gene3D G3DSA:3.40.50.880 1 223 3.4E-81 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L04_02115 fbed101bcdecce56a08ba6c662c2ae75 223 SMART SM01211 1 221 1.7E-134 T 23-10-2018 A3L04_02115 fbed101bcdecce56a08ba6c662c2ae75 223 PIRSF PIRSF001586 1 223 7.3E-86 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L04_02115 fbed101bcdecce56a08ba6c662c2ae75 223 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 3 220 2.3E-99 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L04_01530 0a7faa95d2a4a8f6b8a2eadd34d06434 185 Pfam PF01944 Stage II sporulation protein M 9 178 1.7E-33 T 23-10-2018 IPR002798 Stage II sporulation protein M-like A3L04_06460 5fe8cfa8b646684be39ddb91fc7f5659 714 Gene3D G3DSA:2.60.40.2050 154 273 1.6E-33 T 23-10-2018 A3L04_06460 5fe8cfa8b646684be39ddb91fc7f5659 714 Gene3D G3DSA:1.20.120.870 509 648 6.4E-46 T 23-10-2018 A3L04_00145 a1f779bdde46c4333ff7e746ad6fbce6 229 Hamap MF_00147_A Triosephosphate isomerase [tpiA]. 6 225 44.442 T 23-10-2018 IPR022891 Triosephosphate isomerase, archaeal GO:0004807|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003 A3L04_00145 a1f779bdde46c4333ff7e746ad6fbce6 229 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 8 212 3.8E-65 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_00145 a1f779bdde46c4333ff7e746ad6fbce6 229 Pfam PF05690 Thiazole biosynthesis protein ThiG 166 219 3.0E-6 T 23-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A3L04_00145 a1f779bdde46c4333ff7e746ad6fbce6 229 Pfam PF00121 Triosephosphate isomerase 8 113 6.5E-11 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_00145 a1f779bdde46c4333ff7e746ad6fbce6 229 SUPERFAMILY SSF51351 3 221 2.49E-48 T 23-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_00145 a1f779bdde46c4333ff7e746ad6fbce6 229 Gene3D G3DSA:3.20.20.70 1 225 9.2E-97 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_00145 a1f779bdde46c4333ff7e746ad6fbce6 229 ProSitePatterns PS00171 Triosephosphate isomerase active site. 142 152 - T 23-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L04_01910 18171c497532af9835984a089e610d76 197 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 6 190 1.1E-75 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A3L04_01910 18171c497532af9835984a089e610d76 197 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 10 57 - T 23-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L04_01910 18171c497532af9835984a089e610d76 197 Gene3D G3DSA:3.60.20.10 7 196 4.4E-59 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L04_01910 18171c497532af9835984a089e610d76 197 SUPERFAMILY SSF56235 4 192 1.73E-57 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L04_01910 18171c497532af9835984a089e610d76 197 Hamap MF_02113_A Proteasome subunit beta [prcB]. 2 197 33.974 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A3L04_01910 18171c497532af9835984a089e610d76 197 Pfam PF00227 Proteasome subunit 4 184 3.1E-51 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L04_03810 55a3d9128a411fdf9393d575c5da4af8 366 Gene3D G3DSA:3.90.1150.10 9 348 1.6E-128 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L04_03810 55a3d9128a411fdf9393d575c5da4af8 366 Gene3D G3DSA:3.40.640.10 42 276 1.6E-128 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L04_03810 55a3d9128a411fdf9393d575c5da4af8 366 Pfam PF00202 Aminotransferase class-III 8 357 2.2E-100 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L04_03810 55a3d9128a411fdf9393d575c5da4af8 366 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 199 235 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L04_03810 55a3d9128a411fdf9393d575c5da4af8 366 Hamap MF_02084 [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase [lysJ]. 1 359 44.888 T 23-10-2018 IPR037537 [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase GO:0008483 A3L04_03810 55a3d9128a411fdf9393d575c5da4af8 366 PIRSF PIRSF000521 105 135 0.027 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L04_03810 55a3d9128a411fdf9393d575c5da4af8 366 PIRSF PIRSF000521 8 111 1.6E-7 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L04_03810 55a3d9128a411fdf9393d575c5da4af8 366 PIRSF PIRSF000521 145 361 1.2E-27 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L04_03810 55a3d9128a411fdf9393d575c5da4af8 366 SUPERFAMILY SSF53383 7 361 5.32E-112 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L04_03810 55a3d9128a411fdf9393d575c5da4af8 366 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 3 359 8.6E-148 T 23-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 A3L04_00310 27d7a49c43d0b870088d4ea2e0bcd8ae 443 Gene3D G3DSA:1.20.1250.20 6 199 8.3E-29 T 23-10-2018 A3L04_00310 27d7a49c43d0b870088d4ea2e0bcd8ae 443 SUPERFAMILY SSF103473 9 430 8.63E-65 T 23-10-2018 IPR036259 MFS transporter superfamily A3L04_00310 27d7a49c43d0b870088d4ea2e0bcd8ae 443 Gene3D G3DSA:1.20.1250.20 226 429 1.9E-24 T 23-10-2018 A3L04_00310 27d7a49c43d0b870088d4ea2e0bcd8ae 443 Pfam PF07690 Major Facilitator Superfamily 15 281 8.3E-35 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L04_08430 954f58f3ae89c13d9b22a9c625aceb41 436 Pfam PF13596 PAS domain 316 419 8.7E-23 T 23-10-2018 A3L04_08430 954f58f3ae89c13d9b22a9c625aceb41 436 Pfam PF04282 Family of unknown function (DUF438) 15 79 1.0E-24 T 23-10-2018 IPR007380 Domain of unknown function DUF438 A3L04_08430 954f58f3ae89c13d9b22a9c625aceb41 436 Gene3D G3DSA:1.20.120.520 89 242 2.1E-12 T 23-10-2018 A3L04_08430 954f58f3ae89c13d9b22a9c625aceb41 436 Pfam PF01814 Hemerythrin HHE cation binding domain 92 223 3.9E-19 T 23-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 A3L04_08430 954f58f3ae89c13d9b22a9c625aceb41 436 Gene3D G3DSA:3.30.450.20 297 432 7.3E-45 T 23-10-2018 A3L04_08430 954f58f3ae89c13d9b22a9c625aceb41 436 SUPERFAMILY SSF55785 314 412 3.02E-6 T 23-10-2018 IPR035965 PAS domain superfamily A3L04_08925 61ccb61823c46b7c7e3e2cfdfbdc7d88 182 Pfam PF00005 ABC transporter 14 45 4.6E-6 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_08925 61ccb61823c46b7c7e3e2cfdfbdc7d88 182 Gene3D G3DSA:3.40.50.300 1 137 8.2E-29 T 23-10-2018 A3L04_08925 61ccb61823c46b7c7e3e2cfdfbdc7d88 182 SUPERFAMILY SSF52540 2 114 1.14E-28 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_04810 b4c7054b393049ed4cec01943874aaf2 396 Pfam PF04998 RNA polymerase Rpb1, domain 5 52 333 4.2E-57 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04810 b4c7054b393049ed4cec01943874aaf2 396 TIGRFAM TIGR02389 RNA_pol_rpoA2: DNA-directed RNA polymerase, subunit A'' 18 385 1.7E-154 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_04810 b4c7054b393049ed4cec01943874aaf2 396 Gene3D G3DSA:1.10.150.390 335 380 5.5E-23 T 23-10-2018 A3L04_04810 b4c7054b393049ed4cec01943874aaf2 396 SUPERFAMILY SSF64484 19 386 4.81E-107 T 23-10-2018 A3L04_04810 b4c7054b393049ed4cec01943874aaf2 396 Hamap MF_00411 DNA-directed RNA polymerase subunit A'' [rpoA2]. 3 387 41.984 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L04_07465 e2c40627a1f0c46b537856517ac73184 91 Pfam PF11491 Protein of unknown function (DUF3213) 6 86 3.0E-26 T 23-10-2018 IPR021583 Protein of unknown function DUF3213 A3L04_07465 e2c40627a1f0c46b537856517ac73184 91 Gene3D G3DSA:3.30.70.1750 2 91 2.2E-25 T 23-10-2018 A3L04_07475 94edc78410d9f242b0468ce12b61dc4a 168 Pfam PF01899 Na+/H+ ion antiporter subunit 14 164 4.8E-50 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L04_07475 94edc78410d9f242b0468ce12b61dc4a 168 TIGRFAM TIGR00942 2a6301s05: multicomponent Na+:H+ antiporter 21 168 2.2E-64 T 23-10-2018 IPR004847 Na(+)/H(+) antiporter subunit E1 GO:0015297|GO:0016021|GO:1902600 A3L04_07475 94edc78410d9f242b0468ce12b61dc4a 168 PIRSF PIRSF019239 4 168 6.5E-57 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L04_01660 e6e243eb9129f9e6dcebcbddc31ae7b0 192 SUPERFAMILY SSF52540 3 183 1.43E-32 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01660 e6e243eb9129f9e6dcebcbddc31ae7b0 192 PRINTS PR00449 Transforming protein P21 ras signature 160 182 9.1E-6 T 23-10-2018 A3L04_01660 e6e243eb9129f9e6dcebcbddc31ae7b0 192 PRINTS PR00449 Transforming protein P21 ras signature 121 134 9.1E-6 T 23-10-2018 A3L04_01660 e6e243eb9129f9e6dcebcbddc31ae7b0 192 PRINTS PR00449 Transforming protein P21 ras signature 2 23 9.1E-6 T 23-10-2018 A3L04_01660 e6e243eb9129f9e6dcebcbddc31ae7b0 192 Pfam PF01926 50S ribosome-binding GTPase 4 131 1.1E-19 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_01660 e6e243eb9129f9e6dcebcbddc31ae7b0 192 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 3 174 3.3E-16 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L04_01660 e6e243eb9129f9e6dcebcbddc31ae7b0 192 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 1 182 22.804 T 23-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 A3L04_01660 e6e243eb9129f9e6dcebcbddc31ae7b0 192 Gene3D G3DSA:3.40.50.300 1 186 1.2E-54 T 23-10-2018 A3L04_10190 7118cb17be8c0dd5b72643864a41ba4c 481 SUPERFAMILY SSF52540 1 236 2.11E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_10190 7118cb17be8c0dd5b72643864a41ba4c 481 Gene3D G3DSA:3.40.50.300 3 241 1.1E-46 T 23-10-2018 A3L04_10190 7118cb17be8c0dd5b72643864a41ba4c 481 Gene3D G3DSA:3.40.50.880 247 395 2.1E-16 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L04_10190 7118cb17be8c0dd5b72643864a41ba4c 481 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 229 1.4E-21 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L04_10190 7118cb17be8c0dd5b72643864a41ba4c 481 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 481 160.156 T 23-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 A3L04_10190 7118cb17be8c0dd5b72643864a41ba4c 481 SUPERFAMILY SSF52317 252 442 5.96E-29 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L04_10190 7118cb17be8c0dd5b72643864a41ba4c 481 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 476 6.1E-157 T 23-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 A3L04_10190 7118cb17be8c0dd5b72643864a41ba4c 481 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 250 431 4.5E-50 T 23-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 A3L04_01835 d05356ce4c4a45a2ba79b95fcdeabee3 195 SUPERFAMILY SSF116726 103 175 2.49E-18 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L04_01835 d05356ce4c4a45a2ba79b95fcdeabee3 195 Pfam PF02080 TrkA-C domain 118 175 1.2E-15 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A3L04_01835 d05356ce4c4a45a2ba79b95fcdeabee3 195 Pfam PF01895 PhoU domain 11 95 2.9E-11 T 23-10-2018 IPR026022 PhoU domain A3L04_01835 d05356ce4c4a45a2ba79b95fcdeabee3 195 SUPERFAMILY SSF109755 3 98 3.01E-17 T 23-10-2018 A3L04_01835 d05356ce4c4a45a2ba79b95fcdeabee3 195 Gene3D G3DSA:3.30.70.1450 111 191 2.5E-20 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L04_01835 d05356ce4c4a45a2ba79b95fcdeabee3 195 Gene3D G3DSA:1.20.58.220 1 110 1.7E-21 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L04_04390 74a16b2aec3340e93d19f9201e3a631f 57 PIRSF PIRSF000778 2 57 1.5E-23 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L04_04390 74a16b2aec3340e93d19f9201e3a631f 57 Gene3D G3DSA:3.90.940.50 1 57 4.5E-29 T 23-10-2018 A3L04_04390 74a16b2aec3340e93d19f9201e3a631f 57 Hamap MF_00192 DNA-directed RNA polymerase subunit K [rpoK]. 2 57 22.173 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L04_04390 74a16b2aec3340e93d19f9201e3a631f 57 SUPERFAMILY SSF63562 4 55 7.98E-21 T 23-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L04_04390 74a16b2aec3340e93d19f9201e3a631f 57 Pfam PF01192 RNA polymerase Rpb6 5 51 2.2E-11 T 23-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L04_04390 74a16b2aec3340e93d19f9201e3a631f 57 ProSitePatterns PS01111 RNA polymerases K / 14 to 18 Kd subunits signature. 5 19 - T 23-10-2018 IPR020708 DNA-directed RNA polymerase, 14-18kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L04_02935 16584d999290c44f1d4b9fdb6508fede 306 Gene3D G3DSA:1.10.3720.10 89 305 6.6E-21 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_02935 16584d999290c44f1d4b9fdb6508fede 306 SUPERFAMILY SSF161098 96 304 3.01E-22 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_02935 16584d999290c44f1d4b9fdb6508fede 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 305 1.8E-23 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L04_08180 6a7a2ef6e8f272b2f57c64a2d58bc942 111 Gene3D G3DSA:2.30.130.30 1 110 1.2E-48 T 23-10-2018 A3L04_08180 6a7a2ef6e8f272b2f57c64a2d58bc942 111 Pfam PF04266 ASCH domain 5 108 1.1E-16 T 23-10-2018 IPR007374 ASCH domain A3L04_08180 6a7a2ef6e8f272b2f57c64a2d58bc942 111 SMART SM01022 5 109 8.5E-19 T 23-10-2018 IPR007374 ASCH domain A3L04_08180 6a7a2ef6e8f272b2f57c64a2d58bc942 111 SUPERFAMILY SSF88697 1 108 1.23E-38 T 23-10-2018 IPR015947 PUA-like superfamily A3L04_08180 6a7a2ef6e8f272b2f57c64a2d58bc942 111 PIRSF PIRSF016134 1 111 6.0E-48 T 23-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 A3L04_06995 6c243cec00f5f0b00ce8b4e39bcb1f68 227 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 51 221 1.2E-64 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A3L04_06995 6c243cec00f5f0b00ce8b4e39bcb1f68 227 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 4 223 1.7E-83 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A3L04_06995 6c243cec00f5f0b00ce8b4e39bcb1f68 227 Gene3D G3DSA:3.30.70.260 127 205 9.5E-91 T 23-10-2018 A3L04_06995 6c243cec00f5f0b00ce8b4e39bcb1f68 227 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 225 36.247 T 23-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A3L04_06995 6c243cec00f5f0b00ce8b4e39bcb1f68 227 SUPERFAMILY SSF100950 2 149 3.93E-46 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L04_06995 6c243cec00f5f0b00ce8b4e39bcb1f68 227 SUPERFAMILY SSF75445 131 207 4.97E-24 T 23-10-2018 A3L04_06995 6c243cec00f5f0b00ce8b4e39bcb1f68 227 Gene3D G3DSA:3.40.50.1360 5 221 9.5E-91 T 23-10-2018 A3L04_10550 68f93d487c775ba07fa5b317edb4bb22 160 Pfam PF01917 Archaebacterial flagellin 5 156 1.1E-18 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 A3L04_04130 521828aeb90f4b568d9086112387de5f 117 Pfam PF03551 Transcriptional regulator PadR-like family 27 101 5.9E-20 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L04_04130 521828aeb90f4b568d9086112387de5f 117 SUPERFAMILY SSF46785 10 111 8.75E-22 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_04130 521828aeb90f4b568d9086112387de5f 117 Gene3D G3DSA:1.10.10.10 5 117 1.4E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_07910 3dad0e4d28f1161873746fd260a75d58 67 Pfam PF01246 Ribosomal protein L24e 3 63 1.7E-26 T 23-10-2018 IPR000988 Ribosomal protein L24e-related A3L04_07910 3dad0e4d28f1161873746fd260a75d58 67 Hamap MF_00773 50S ribosomal protein L24e [rpl24e]. 2 55 26.236 T 23-10-2018 IPR023438 Ribosomal protein L24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_07910 3dad0e4d28f1161873746fd260a75d58 67 ProSitePatterns PS01073 Ribosomal protein L24e signature. 9 26 - T 23-10-2018 IPR023442 Ribosomal protein L24e, conserved site A3L04_07910 3dad0e4d28f1161873746fd260a75d58 67 SUPERFAMILY SSF57716 6 57 7.98E-21 T 23-10-2018 A3L04_07910 3dad0e4d28f1161873746fd260a75d58 67 SMART SM00746 7 45 3.2E-12 T 23-10-2018 IPR011017 TRASH domain A3L04_07910 3dad0e4d28f1161873746fd260a75d58 67 Gene3D G3DSA:2.30.170.20 2 66 6.6E-27 T 23-10-2018 IPR038630 Ribosomal protein L24e/L24 superfamily A3L04_05610 09dfbcc3a34bec221e1733b0504b63a6 321 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 1 306 1.8E-49 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 A3L04_05610 09dfbcc3a34bec221e1733b0504b63a6 321 Gene3D G3DSA:3.30.230.10 16 141 2.5E-9 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L04_05610 09dfbcc3a34bec221e1733b0504b63a6 321 PIRSF PIRSF004884 1 309 6.5E-108 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 A3L04_05610 09dfbcc3a34bec221e1733b0504b63a6 321 Pfam PF08544 GHMP kinases C terminal 203 280 1.5E-4 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain A3L04_05610 09dfbcc3a34bec221e1733b0504b63a6 321 SUPERFAMILY SSF54211 1 149 2.13E-15 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L04_03525 a0888d26148d220f310eea18d9fe9dc7 475 Gene3D G3DSA:3.50.50.60 234 364 2.6E-58 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_03525 a0888d26148d220f310eea18d9fe9dc7 475 SUPERFAMILY SSF51905 110 430 2.19E-41 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_03525 a0888d26148d220f310eea18d9fe9dc7 475 Gene3D G3DSA:3.10.20.440 6 97 3.6E-30 T 23-10-2018 A3L04_03525 a0888d26148d220f310eea18d9fe9dc7 475 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 60 68 - T 23-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A3L04_03525 a0888d26148d220f310eea18d9fe9dc7 475 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 116 422 3.3E-40 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L04_03525 a0888d26148d220f310eea18d9fe9dc7 475 SUPERFAMILY SSF54292 17 100 2.29E-21 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A3L04_03525 a0888d26148d220f310eea18d9fe9dc7 475 Gene3D G3DSA:3.50.50.60 116 437 2.6E-58 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_03525 a0888d26148d220f310eea18d9fe9dc7 475 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 15 95 4.5E-26 T 23-10-2018 A3L04_03525 a0888d26148d220f310eea18d9fe9dc7 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 116 138 9.9E-18 T 23-10-2018 A3L04_03525 a0888d26148d220f310eea18d9fe9dc7 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 291 9.9E-18 T 23-10-2018 A3L04_03525 a0888d26148d220f310eea18d9fe9dc7 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 357 371 9.9E-18 T 23-10-2018 A3L04_03525 a0888d26148d220f310eea18d9fe9dc7 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 403 410 9.9E-18 T 23-10-2018 A3L04_03525 a0888d26148d220f310eea18d9fe9dc7 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 372 8.0E-25 T 23-10-2018 A3L04_03525 a0888d26148d220f310eea18d9fe9dc7 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 117 136 8.0E-25 T 23-10-2018 A3L04_03525 a0888d26148d220f310eea18d9fe9dc7 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 222 240 8.0E-25 T 23-10-2018 A3L04_03525 a0888d26148d220f310eea18d9fe9dc7 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 388 410 8.0E-25 T 23-10-2018 A3L04_03525 a0888d26148d220f310eea18d9fe9dc7 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 284 8.0E-25 T 23-10-2018 A3L04_02095 e81c7e628b458b5bc47eca3206de95a4 335 Gene3D G3DSA:3.40.50.300 3 335 2.1E-99 T 23-10-2018 A3L04_02095 e81c7e628b458b5bc47eca3206de95a4 335 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_02095 e81c7e628b458b5bc47eca3206de95a4 335 Pfam PF00005 ABC transporter 37 191 1.7E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_02095 e81c7e628b458b5bc47eca3206de95a4 335 SMART SM00382 45 249 1.7E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_02095 e81c7e628b458b5bc47eca3206de95a4 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 309 6.0E-19 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L04_02095 e81c7e628b458b5bc47eca3206de95a4 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 331 2.9E-28 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L04_02095 e81c7e628b458b5bc47eca3206de95a4 335 SUPERFAMILY SSF52540 6 263 7.14E-71 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_03200 be625e0e85fd10b72b6e5146943df533 158 SUPERFAMILY SSF55040 12 153 9.15E-51 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L04_03200 be625e0e85fd10b72b6e5146943df533 158 Pfam PF01967 MoaC family 14 152 2.6E-51 T 23-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L04_03200 be625e0e85fd10b72b6e5146943df533 158 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 139 8.4E-56 T 23-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L04_03200 be625e0e85fd10b72b6e5146943df533 158 Gene3D G3DSA:3.30.70.640 1 158 5.6E-69 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L04_03200 be625e0e85fd10b72b6e5146943df533 158 Hamap MF_01224_A Cyclic pyranopterin monophosphate synthase [moaC]. 9 154 39.635 T 23-10-2018 IPR023047 Probable cyclic pyranopterin monophosphate synthase accessory protein, archaea KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823 A3L04_03070 0ffcdf7a93297f569d16701c0723c70f 203 Hamap MF_01078 UPF0278 protein . 1 194 32.1 T 23-10-2018 IPR014856 PIN-domain ribonuclease A3L04_03070 0ffcdf7a93297f569d16701c0723c70f 203 Pfam PF08745 PINc domain ribonuclease 3 191 2.2E-67 T 23-10-2018 IPR014856 PIN-domain ribonuclease A3L04_03070 0ffcdf7a93297f569d16701c0723c70f 203 TIGRFAM TIGR03875 RNA_lig_partner: RNA ligase partner, MJ_0950 family 3 190 3.3E-71 T 23-10-2018 IPR014856 PIN-domain ribonuclease A3L04_03070 0ffcdf7a93297f569d16701c0723c70f 203 SUPERFAMILY SSF88723 76 193 1.01E-7 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_09980 0aeafe543949d4860083f0106e864809 115 SUPERFAMILY SSF52833 7 113 3.65E-19 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L04_09980 0aeafe543949d4860083f0106e864809 115 Pfam PF13192 Thioredoxin domain 33 101 2.6E-12 T 23-10-2018 IPR012336 Thioredoxin-like fold A3L04_09980 0aeafe543949d4860083f0106e864809 115 Gene3D G3DSA:3.40.30.10 11 109 1.2E-18 T 23-10-2018 A3L04_01860 8f90140b3845cf4bee4582e0d5c9e022 218 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 1 216 2.9E-78 T 23-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 A3L04_01860 8f90140b3845cf4bee4582e0d5c9e022 218 Pfam PF01987 Mitochondrial biogenesis AIM24 3 202 2.2E-61 T 23-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 A3L04_01860 8f90140b3845cf4bee4582e0d5c9e022 218 Gene3D G3DSA:3.60.160.10 1 218 3.6E-81 T 23-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily A3L04_01860 8f90140b3845cf4bee4582e0d5c9e022 218 SUPERFAMILY SSF51219 1 217 3.92E-71 T 23-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily A3L04_05440 e5ffa3d162e7fa3347955bf86b7c005a 323 Pfam PF01594 AI-2E family transporter 9 314 4.6E-32 T 23-10-2018 IPR002549 Transmembrane protein TqsA-like A3L04_05470 8ed1da403570cabb4e7345bcf8063d13 440 SUPERFAMILY SSF56281 2 439 2.88E-67 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_05470 8ed1da403570cabb4e7345bcf8063d13 440 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 378 406 - T 23-10-2018 IPR001587 Ribonuclease J, conserved site A3L04_05470 8ed1da403570cabb4e7345bcf8063d13 440 Gene3D G3DSA:3.40.50.10710 215 374 3.3E-138 T 23-10-2018 A3L04_05470 8ed1da403570cabb4e7345bcf8063d13 440 Hamap MF_01492 Ribonuclease J [rnj]. 1 440 51.692 T 23-10-2018 IPR030879 Ribonuclease J, archaea GO:0003723|GO:0004534|GO:0090503 A3L04_05470 8ed1da403570cabb4e7345bcf8063d13 440 SMART SM00849 14 221 2.6E-21 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_05470 8ed1da403570cabb4e7345bcf8063d13 440 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 2 439 3.8E-171 T 23-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 A3L04_05470 8ed1da403570cabb4e7345bcf8063d13 440 Pfam PF00753 Metallo-beta-lactamase superfamily 13 183 2.4E-11 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_05470 8ed1da403570cabb4e7345bcf8063d13 440 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 371 430 3.7E-13 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A3L04_05470 8ed1da403570cabb4e7345bcf8063d13 440 Gene3D G3DSA:3.60.15.10 3 439 3.3E-138 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_01080 8ec2c866abb6e68fcccef8a7a4b3bbb6 213 Gene3D G3DSA:3.30.980.10 85 213 2.1E-46 T 23-10-2018 A3L04_01080 8ec2c866abb6e68fcccef8a7a4b3bbb6 213 SUPERFAMILY SSF50447 1 84 1.94E-22 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L04_01080 8ec2c866abb6e68fcccef8a7a4b3bbb6 213 Gene3D G3DSA:2.40.30.130 13 84 4.1E-34 T 23-10-2018 A3L04_01080 8ec2c866abb6e68fcccef8a7a4b3bbb6 213 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 171 209 7.6E-10 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L04_01080 8ec2c866abb6e68fcccef8a7a4b3bbb6 213 SUPERFAMILY SSF55186 85 211 6.02E-34 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A3L04_01080 8ec2c866abb6e68fcccef8a7a4b3bbb6 213 SMART SM00863 166 209 5.2E-10 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L04_01080 8ec2c866abb6e68fcccef8a7a4b3bbb6 213 Pfam PF01411 tRNA synthetases class II (A) 13 87 1.8E-13 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A3L04_00990 c9f09e557a6112060a5dd3b0c893d500 169 SUPERFAMILY SSF56399 1 166 1.09E-55 T 23-10-2018 A3L04_00990 c9f09e557a6112060a5dd3b0c893d500 169 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 1 165 30.005 T 23-10-2018 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 A3L04_00990 c9f09e557a6112060a5dd3b0c893d500 169 Gene3D G3DSA:3.20.170.30 84 169 1.5E-31 T 23-10-2018 A3L04_00990 c9f09e557a6112060a5dd3b0c893d500 169 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 1 154 3.2E-31 T 23-10-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 A3L04_00990 c9f09e557a6112060a5dd3b0c893d500 169 Gene3D G3DSA:1.10.10.970 1 64 4.3E-21 T 23-10-2018 A3L04_03935 7308f1ded21ea9973b003ca581cc8aaf 190 Pfam PF00117 Glutamine amidotransferase class-I 4 174 2.7E-45 T 23-10-2018 IPR017926 Glutamine amidotransferase A3L04_03935 7308f1ded21ea9973b003ca581cc8aaf 190 PRINTS PR00097 Anthranilate synthase component II signature 73 84 1.6E-29 T 23-10-2018 A3L04_03935 7308f1ded21ea9973b003ca581cc8aaf 190 PRINTS PR00097 Anthranilate synthase component II signature 2 16 1.6E-29 T 23-10-2018 A3L04_03935 7308f1ded21ea9973b003ca581cc8aaf 190 PRINTS PR00097 Anthranilate synthase component II signature 45 54 1.6E-29 T 23-10-2018 A3L04_03935 7308f1ded21ea9973b003ca581cc8aaf 190 PRINTS PR00097 Anthranilate synthase component II signature 97 105 1.6E-29 T 23-10-2018 A3L04_03935 7308f1ded21ea9973b003ca581cc8aaf 190 PRINTS PR00097 Anthranilate synthase component II signature 161 174 1.6E-29 T 23-10-2018 A3L04_03935 7308f1ded21ea9973b003ca581cc8aaf 190 PRINTS PR00097 Anthranilate synthase component II signature 117 129 1.6E-29 T 23-10-2018 A3L04_03935 7308f1ded21ea9973b003ca581cc8aaf 190 Gene3D G3DSA:3.40.50.880 1 190 1.0E-53 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L04_03935 7308f1ded21ea9973b003ca581cc8aaf 190 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 73 89 7.3E-10 T 23-10-2018 A3L04_03935 7308f1ded21ea9973b003ca581cc8aaf 190 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 42 56 7.3E-10 T 23-10-2018 A3L04_03935 7308f1ded21ea9973b003ca581cc8aaf 190 PRINTS PR00096 Glutamine amidotransferase superfamily signature 73 84 8.4E-14 T 23-10-2018 A3L04_03935 7308f1ded21ea9973b003ca581cc8aaf 190 PRINTS PR00096 Glutamine amidotransferase superfamily signature 45 54 8.4E-14 T 23-10-2018 A3L04_03935 7308f1ded21ea9973b003ca581cc8aaf 190 PRINTS PR00096 Glutamine amidotransferase superfamily signature 161 174 8.4E-14 T 23-10-2018 A3L04_03935 7308f1ded21ea9973b003ca581cc8aaf 190 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 187 3.9E-47 T 23-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A3L04_03935 7308f1ded21ea9973b003ca581cc8aaf 190 SUPERFAMILY SSF52317 1 188 1.69E-49 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L04_04170 f15bfcd908fa2c2de62ae2f74d8706c8 324 Gene3D G3DSA:3.40.50.620 1 323 4.1E-87 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_04170 f15bfcd908fa2c2de62ae2f74d8706c8 324 PIRSF PIRSF004976 1 314 3.8E-113 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 A3L04_04170 f15bfcd908fa2c2de62ae2f74d8706c8 324 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 202 302 2.0E-37 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 A3L04_04170 f15bfcd908fa2c2de62ae2f74d8706c8 324 SUPERFAMILY SSF52402 25 255 1.24E-55 T 23-10-2018 A3L04_04170 f15bfcd908fa2c2de62ae2f74d8706c8 324 Pfam PF01171 PP-loop family 50 227 4.7E-15 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A3L04_01380 f13e233c4bba905b7086da97165e6bfc 339 Pfam PF07885 Ion channel 32 100 6.5E-17 T 23-10-2018 IPR013099 Potassium channel domain A3L04_01380 f13e233c4bba905b7086da97165e6bfc 339 Pfam PF02254 TrkA-N domain 129 241 4.9E-16 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A3L04_01380 f13e233c4bba905b7086da97165e6bfc 339 Gene3D G3DSA:1.10.287.70 5 103 4.7E-21 T 23-10-2018 A3L04_01380 f13e233c4bba905b7086da97165e6bfc 339 Gene3D G3DSA:3.40.50.720 113 256 1.3E-27 T 23-10-2018 A3L04_01380 f13e233c4bba905b7086da97165e6bfc 339 SUPERFAMILY SSF81324 18 131 3.79E-27 T 23-10-2018 A3L04_01380 f13e233c4bba905b7086da97165e6bfc 339 SUPERFAMILY SSF51735 116 264 1.67E-18 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_10685 9dd4dac8f8446fd1a4bbd59700646c4c 126 SUPERFAMILY SSF81301 32 111 3.54E-18 T 23-10-2018 A3L04_10685 9dd4dac8f8446fd1a4bbd59700646c4c 126 Gene3D G3DSA:3.30.460.10 26 118 6.3E-18 T 23-10-2018 A3L04_10685 9dd4dac8f8446fd1a4bbd59700646c4c 126 Pfam PF01909 Nucleotidyltransferase domain 32 111 2.8E-8 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L04_00365 07dbbd182ca72cf52bda4d0100e2bec2 224 Gene3D G3DSA:3.40.50.1000 3 135 3.0E-13 T 23-10-2018 IPR023214 HAD superfamily A3L04_00365 07dbbd182ca72cf52bda4d0100e2bec2 224 Gene3D G3DSA:1.10.150.520 14 85 3.0E-13 T 23-10-2018 A3L04_00365 07dbbd182ca72cf52bda4d0100e2bec2 224 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 134 4.4E-11 T 23-10-2018 A3L04_00365 07dbbd182ca72cf52bda4d0100e2bec2 224 SUPERFAMILY SSF56784 1 186 1.01E-19 T 23-10-2018 IPR036412 HAD-like superfamily A3L04_05870 405ca0bacd63f79681ee6307d51de741 105 Gene3D G3DSA:3.30.70.20 25 105 9.1E-16 T 23-10-2018 A3L04_05870 405ca0bacd63f79681ee6307d51de741 105 Pfam PF14697 4Fe-4S dicluster domain 48 100 5.5E-11 T 23-10-2018 A3L04_05870 405ca0bacd63f79681ee6307d51de741 105 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 28 103 9.1E-36 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 A3L04_05870 405ca0bacd63f79681ee6307d51de741 105 SUPERFAMILY SSF54862 27 102 6.58E-24 T 23-10-2018 A3L04_05870 405ca0bacd63f79681ee6307d51de741 105 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_05105 5204a3db85a7d8db6ada29afe150c691 632 Pfam PF00583 Acetyltransferase (GNAT) family 277 341 3.4E-5 T 23-10-2018 IPR000182 GNAT domain A3L04_05105 5204a3db85a7d8db6ada29afe150c691 632 Pfam PF00005 ABC transporter 437 573 3.5E-19 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_05105 5204a3db85a7d8db6ada29afe150c691 632 Gene3D G3DSA:3.40.50.300 398 631 3.7E-40 T 23-10-2018 A3L04_05105 5204a3db85a7d8db6ada29afe150c691 632 Gene3D G3DSA:3.40.630.30 222 353 4.3E-9 T 23-10-2018 A3L04_05105 5204a3db85a7d8db6ada29afe150c691 632 SUPERFAMILY SSF52540 422 628 2.67E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_05105 5204a3db85a7d8db6ada29afe150c691 632 SMART SM00382 446 625 1.0E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_05105 5204a3db85a7d8db6ada29afe150c691 632 SUPERFAMILY SSF55729 113 347 5.52E-9 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L04_09905 54d9a6613e1e5fe4b4c4df6db080dee2 457 Gene3D G3DSA:3.90.1150.10 17 437 2.0E-141 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L04_09905 54d9a6613e1e5fe4b4c4df6db080dee2 457 SUPERFAMILY SSF53383 32 442 2.19E-113 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L04_09905 54d9a6613e1e5fe4b4c4df6db080dee2 457 Gene3D G3DSA:3.40.640.10 71 341 2.0E-141 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L04_09905 54d9a6613e1e5fe4b4c4df6db080dee2 457 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 259 296 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L04_09905 54d9a6613e1e5fe4b4c4df6db080dee2 457 PIRSF PIRSF000521 136 444 7.7E-39 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L04_09905 54d9a6613e1e5fe4b4c4df6db080dee2 457 PIRSF PIRSF000521 1 140 5.4E-11 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L04_09905 54d9a6613e1e5fe4b4c4df6db080dee2 457 Pfam PF00202 Aminotransferase class-III 35 441 1.2E-103 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L04_00640 9791c0e0b38bf8041854ee533638d928 237 SUPERFAMILY SSF47240 50 184 1.51E-13 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L04_00640 9791c0e0b38bf8041854ee533638d928 237 Pfam PF09968 Uncharacterized protein domain (DUF2202) 51 211 9.6E-63 T 23-10-2018 IPR019243 Domain of unknown function DUF2202 A3L04_00640 9791c0e0b38bf8041854ee533638d928 237 Gene3D G3DSA:1.20.1260.10 46 216 4.3E-65 T 23-10-2018 IPR012347 Ferritin-like A3L04_00705 752a42fd1047c4cb4d6e1ddc77f85d10 555 Pfam PF04389 Peptidase family M28 222 404 2.2E-18 T 23-10-2018 IPR007484 Peptidase M28 A3L04_00705 752a42fd1047c4cb4d6e1ddc77f85d10 555 SUPERFAMILY SSF53187 5 411 9.83E-31 T 23-10-2018 A3L04_00705 752a42fd1047c4cb4d6e1ddc77f85d10 555 Gene3D G3DSA:3.50.30.30 68 203 1.0E-51 T 23-10-2018 A3L04_00705 752a42fd1047c4cb4d6e1ddc77f85d10 555 Gene3D G3DSA:3.40.630.10 25 397 1.0E-51 T 23-10-2018 A3L04_04445 4e3c7792ce25c8e3b87515d0728f2634 370 Pfam PF04007 Protein of unknown function (DUF354) 1 340 1.0E-102 T 23-10-2018 IPR007152 Protein of unknown function DUF354 A3L04_04445 4e3c7792ce25c8e3b87515d0728f2634 370 PIRSF PIRSF005357 1 348 4.8E-130 T 23-10-2018 IPR007152 Protein of unknown function DUF354 A3L04_04445 4e3c7792ce25c8e3b87515d0728f2634 370 SUPERFAMILY SSF53756 1 324 2.61E-26 T 23-10-2018 A3L04_03170 b823b3b0483deb71912af9d53f1d22c6 189 Gene3D G3DSA:3.40.390.10 11 177 2.3E-48 T 23-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 A3L04_03170 b823b3b0483deb71912af9d53f1d22c6 189 Pfam PF07998 Peptidase family M54 40 177 1.3E-29 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 A3L04_03170 b823b3b0483deb71912af9d53f1d22c6 189 Hamap MF_01842 Archaemetzincin [amzA]. 1 177 38.195 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 A3L04_03170 b823b3b0483deb71912af9d53f1d22c6 189 PIRSF PIRSF005785 1 186 1.5E-65 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 A3L04_03170 b823b3b0483deb71912af9d53f1d22c6 189 SUPERFAMILY SSF55486 46 174 1.16E-16 T 23-10-2018 A3L04_10000 ff30349018e5aeebddbbf96dcf3d3379 204 Gene3D G3DSA:1.10.1760.20 1 197 9.0E-66 T 23-10-2018 A3L04_10000 ff30349018e5aeebddbbf96dcf3d3379 204 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 198 1.3E-62 T 23-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 A3L04_02315 cb4266f5c8201ed500900f15a66ad751 307 Gene3D G3DSA:1.10.10.10 154 200 1.9E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_02315 cb4266f5c8201ed500900f15a66ad751 307 SUPERFAMILY SSF46785 156 200 2.67E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_09405 32e61bb95af825a8e7cd6b0d0e8b2139 296 Gene3D G3DSA:3.40.225.10 121 296 2.3E-52 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L04_09405 32e61bb95af825a8e7cd6b0d0e8b2139 296 Pfam PF10120 Thiamine-phosphate synthase 132 290 4.8E-52 T 23-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L04_09405 32e61bb95af825a8e7cd6b0d0e8b2139 296 SUPERFAMILY SSF53639 126 292 2.9E-50 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L04_03585 c9646148b73a47de133185681d92db8a 388 SUPERFAMILY SSF103473 24 384 3.01E-30 T 23-10-2018 IPR036259 MFS transporter superfamily A3L04_03585 c9646148b73a47de133185681d92db8a 388 Pfam PF07690 Major Facilitator Superfamily 248 383 7.5E-9 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L04_03585 c9646148b73a47de133185681d92db8a 388 Gene3D G3DSA:1.20.1250.20 22 385 1.6E-27 T 23-10-2018 A3L04_00560 86ed8a379271bbd16ffb8a73369f2e30 91 PIRSF PIRSF006521 3 91 4.0E-33 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 A3L04_00560 86ed8a379271bbd16ffb8a73369f2e30 91 Gene3D G3DSA:3.30.70.60 1 91 1.6E-36 T 23-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 A3L04_00560 86ed8a379271bbd16ffb8a73369f2e30 91 TIGRFAM TIGR00489 aEF-1_beta: translation elongation factor aEF-1 beta 7 90 5.8E-22 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 A3L04_00560 86ed8a379271bbd16ffb8a73369f2e30 91 SUPERFAMILY SSF54984 9 91 1.57E-21 T 23-10-2018 IPR036219 Translation elongation factor eEF-1beta-like superfamily Reactome: R-HSA-156842 A3L04_00560 86ed8a379271bbd16ffb8a73369f2e30 91 SMART SM00888 5 91 1.0E-33 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 A3L04_00560 86ed8a379271bbd16ffb8a73369f2e30 91 Pfam PF00736 EF-1 guanine nucleotide exchange domain 9 91 6.8E-22 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 A3L04_00560 86ed8a379271bbd16ffb8a73369f2e30 91 Hamap MF_00043 Elongation factor 1-beta [ef1b]. 1 91 40.824 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 A3L04_04240 efbcc70f87e6bcca9ef070482622207a 385 Gene3D G3DSA:3.40.50.920 272 383 2.3E-25 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L04_04240 efbcc70f87e6bcca9ef070482622207a 385 Gene3D G3DSA:3.40.50.970 1 199 1.3E-86 T 23-10-2018 A3L04_04240 efbcc70f87e6bcca9ef070482622207a 385 SUPERFAMILY SSF52922 274 381 9.03E-27 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L04_04240 efbcc70f87e6bcca9ef070482622207a 385 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 282 376 1.9E-20 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A3L04_04240 efbcc70f87e6bcca9ef070482622207a 385 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 22 257 9.2E-82 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L04_04240 efbcc70f87e6bcca9ef070482622207a 385 SUPERFAMILY SSF52518 12 267 1.03E-72 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L04_02590 c113b34b03d3e388840d5585e54b4c8c 366 SUPERFAMILY SSF53756 4 364 7.63E-71 T 23-10-2018 A3L04_02590 c113b34b03d3e388840d5585e54b4c8c 366 Pfam PF13439 Glycosyltransferase Family 4 16 184 1.5E-22 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L04_02590 c113b34b03d3e388840d5585e54b4c8c 366 Gene3D G3DSA:3.40.50.2000 16 361 1.5E-65 T 23-10-2018 A3L04_02590 c113b34b03d3e388840d5585e54b4c8c 366 Gene3D G3DSA:3.40.50.2000 180 351 1.5E-65 T 23-10-2018 A3L04_02590 c113b34b03d3e388840d5585e54b4c8c 366 Pfam PF00534 Glycosyl transferases group 1 186 336 8.3E-38 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L04_02250 fa875fb02b2020b0c6ace368b20892a4 158 Gene3D G3DSA:3.40.630.30 1 158 3.7E-53 T 23-10-2018 A3L04_02250 fa875fb02b2020b0c6ace368b20892a4 158 SUPERFAMILY SSF55729 1 147 6.06E-31 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L04_02250 fa875fb02b2020b0c6ace368b20892a4 158 Pfam PF00583 Acetyltransferase (GNAT) family 40 141 4.3E-21 T 23-10-2018 IPR000182 GNAT domain A3L04_07350 f682d5f7877a32de2f92daec4b568db8 222 Hamap MF_00264 UPF0128 protein . 1 222 138.778 T 23-10-2018 IPR005266 Uncharacterised protein family UPF0128 A3L04_07350 f682d5f7877a32de2f92daec4b568db8 222 PIRSF PIRSF016179 1 222 6.1E-107 T 23-10-2018 IPR005266 Uncharacterised protein family UPF0128 A3L04_07350 f682d5f7877a32de2f92daec4b568db8 222 Pfam PF03673 Uncharacterised protein family (UPF0128) 2 222 7.8E-105 T 23-10-2018 IPR005266 Uncharacterised protein family UPF0128 A3L04_07350 f682d5f7877a32de2f92daec4b568db8 222 ProDom PD023377 UPF0128 PYRAB08320 PH1314 PF1488 MJ1463 AQ_756 1 222 4.0E-112 T 23-10-2018 IPR005266 Uncharacterised protein family UPF0128 A3L04_07350 f682d5f7877a32de2f92daec4b568db8 222 TIGRFAM TIGR00703 TIGR00703: TIGR00703 family protein 2 222 8.1E-107 T 23-10-2018 IPR005266 Uncharacterised protein family UPF0128 A3L04_04265 2b53d4d1e016a471ba7621d94c696464 189 SUPERFAMILY SSF88697 7 110 2.65E-19 T 23-10-2018 IPR015947 PUA-like superfamily A3L04_04265 2b53d4d1e016a471ba7621d94c696464 189 SMART SM01022 10 111 2.9E-20 T 23-10-2018 IPR007374 ASCH domain A3L04_04265 2b53d4d1e016a471ba7621d94c696464 189 Pfam PF04266 ASCH domain 12 110 2.6E-20 T 23-10-2018 IPR007374 ASCH domain A3L04_07855 551a56916e1dcbfe7d37a6e1518421b7 120 SUPERFAMILY SSF160350 5 117 2.62E-36 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 A3L04_07855 551a56916e1dcbfe7d37a6e1518421b7 120 Gene3D G3DSA:3.30.70.3250 1 120 3.5E-48 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 A3L04_07855 551a56916e1dcbfe7d37a6e1518421b7 120 PIRSF PIRSF004952 4 120 1.4E-48 T 23-10-2018 IPR016434 Ribonuclease P, protein component 2 GO:0001682|GO:0004526 A3L04_07855 551a56916e1dcbfe7d37a6e1518421b7 120 Hamap MF_00755 Ribonuclease P protein component 2 [rnp2]. 5 116 28.857 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 A3L04_07855 551a56916e1dcbfe7d37a6e1518421b7 120 Pfam PF01900 Rpp14/Pop5 family 17 113 1.8E-23 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 A3L04_09410 95f967678c68f0d9c4805deb986e7683 376 TIGRFAM TIGR04289 heavy_Cys: eight-cysteine-cluster domain 147 198 4.3E-21 T 23-10-2018 IPR027553 Eight-cysteine-cluster domain A3L04_09410 95f967678c68f0d9c4805deb986e7683 376 TIGRFAM TIGR04292 heavy_Cys_CGP: heavy-Cys/CGP-CTERM domain protein 17 375 7.3E-132 T 23-10-2018 IPR027556 Heavy-Cys/GCP-CTERM domain protein A3L04_01895 aaff593b5b4e563d3841516ca6b3e97e 971 Gene3D G3DSA:2.40.128.390 602 684 5.7E-118 T 23-10-2018 A3L04_01895 aaff593b5b4e563d3841516ca6b3e97e 971 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 103 208 7.8E-6 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A3L04_01895 aaff593b5b4e563d3841516ca6b3e97e 971 Gene3D G3DSA:2.60.40.3030 820 952 7.3E-114 T 23-10-2018 A3L04_01895 aaff593b5b4e563d3841516ca6b3e97e 971 Gene3D G3DSA:2.60.40.3020 727 965 7.3E-114 T 23-10-2018 A3L04_01895 aaff593b5b4e563d3841516ca6b3e97e 971 Gene3D G3DSA:3.40.50.12610 488 725 5.7E-118 T 23-10-2018 A3L04_00320 a9d69a8782da876dff89bba45831f861 284 Gene3D G3DSA:3.40.50.1820 22 284 1.3E-44 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L04_00320 a9d69a8782da876dff89bba45831f861 284 SUPERFAMILY SSF53474 12 284 8.45E-52 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L04_00320 a9d69a8782da876dff89bba45831f861 284 Pfam PF12697 Alpha/beta hydrolase family 69 198 1.5E-11 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A3L04_02770 c8c92324a1d9528ef56511756b104c55 335 Gene3D G3DSA:3.30.70.2940 1 79 8.3E-22 T 23-10-2018 A3L04_02770 c8c92324a1d9528ef56511756b104c55 335 TIGRFAM TIGR01888 cas_cmr3: CRISPR type III-B/RAMP module-associated protein Cmr3 4 330 1.2E-52 T 23-10-2018 IPR010165 CRISPR-associated protein, TM1793 A3L04_02770 c8c92324a1d9528ef56511756b104c55 335 Gene3D G3DSA:3.30.70.2950 234 335 7.3E-33 T 23-10-2018 A3L04_02770 c8c92324a1d9528ef56511756b104c55 335 Pfam PF09700 CRISPR-associated protein (Cas_Cmr3) 5 333 5.8E-49 T 23-10-2018 IPR019117 CRISPR-associated protein, Cmr3 A3L04_03515 39e2d099522a5abc3401545b967fff1a 86 Pfam PF04324 BFD-like [2Fe-2S] binding domain 3 55 4.6E-14 T 23-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A3L04_03515 39e2d099522a5abc3401545b967fff1a 86 Gene3D G3DSA:1.10.10.1100 1 64 2.2E-21 T 23-10-2018 A3L04_10005 66e2d1aadfeb3e1dc1d52ee9eb9f1c9e 457 Gene3D G3DSA:3.40.50.261 129 287 4.4E-60 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L04_10005 66e2d1aadfeb3e1dc1d52ee9eb9f1c9e 457 Gene3D G3DSA:3.40.50.261 288 457 4.1E-69 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L04_10005 66e2d1aadfeb3e1dc1d52ee9eb9f1c9e 457 SUPERFAMILY SSF51735 1 129 1.29E-41 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_10005 66e2d1aadfeb3e1dc1d52ee9eb9f1c9e 457 SMART SM00881 5 99 4.7E-38 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L04_10005 66e2d1aadfeb3e1dc1d52ee9eb9f1c9e 457 SUPERFAMILY SSF52210 291 450 4.45E-42 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L04_10005 66e2d1aadfeb3e1dc1d52ee9eb9f1c9e 457 Pfam PF13380 CoA binding domain 10 134 6.3E-29 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L04_10005 66e2d1aadfeb3e1dc1d52ee9eb9f1c9e 457 SUPERFAMILY SSF52210 131 287 1.83E-45 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L04_10005 66e2d1aadfeb3e1dc1d52ee9eb9f1c9e 457 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 149 286 1.1E-54 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L04_10005 66e2d1aadfeb3e1dc1d52ee9eb9f1c9e 457 Gene3D G3DSA:3.40.50.720 1 128 9.8E-50 T 23-10-2018 A3L04_02085 6879edc7fc92379e300b5e38c9a8f0f8 477 SUPERFAMILY SSF161098 264 458 1.44E-22 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_02085 6879edc7fc92379e300b5e38c9a8f0f8 477 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 288 476 5.6E-29 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L04_02085 6879edc7fc92379e300b5e38c9a8f0f8 477 Gene3D G3DSA:1.10.3720.10 257 476 2.2E-21 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_02085 6879edc7fc92379e300b5e38c9a8f0f8 477 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 11 50 7.2E-7 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A3L04_01110 026dd673a965479e8ea2beff08a8f005 269 Gene3D G3DSA:3.60.20.10 1 183 9.7E-16 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L04_01110 026dd673a965479e8ea2beff08a8f005 269 Pfam PF13230 Glutamine amidotransferases class-II 31 122 1.9E-9 T 23-10-2018 IPR026869 Putative glutamine amidotransferase type 2 A3L04_01110 026dd673a965479e8ea2beff08a8f005 269 SUPERFAMILY SSF56235 36 166 1.09E-14 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L04_08375 a749368ad3c184e922c640bf62e9a796 384 Pfam PF13649 Methyltransferase domain 87 141 2.0E-8 T 23-10-2018 A3L04_08375 a749368ad3c184e922c640bf62e9a796 384 SUPERFAMILY SSF53335 55 160 3.7E-19 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_08375 a749368ad3c184e922c640bf62e9a796 384 Gene3D G3DSA:3.40.50.150 42 235 3.7E-25 T 23-10-2018 A3L04_02160 200f8d3370b2646fd6fe2688a7add76e 534 Gene3D G3DSA:3.80.30.20 213 409 5.1E-12 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L04_02160 200f8d3370b2646fd6fe2688a7add76e 534 Pfam PF04055 Radical SAM superfamily 218 402 1.9E-18 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_02160 200f8d3370b2646fd6fe2688a7add76e 534 SUPERFAMILY SSF102114 215 445 7.46E-12 T 23-10-2018 A3L04_02160 200f8d3370b2646fd6fe2688a7add76e 534 SMART SM00729 214 449 2.4E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L04_08720 8b8a5f918cd0d5e9fb8f3448c15ae5f6 268 Hamap MF_00840 Diadenylate cyclase [dacZ]. 6 264 35.975 T 23-10-2018 IPR014499 Diadenylate cyclase, DacZ-type A3L04_08720 8b8a5f918cd0d5e9fb8f3448c15ae5f6 268 PIRSF PIRSF019073 1 268 7.7E-97 T 23-10-2018 IPR014499 Diadenylate cyclase, DacZ-type A3L04_08720 8b8a5f918cd0d5e9fb8f3448c15ae5f6 268 Gene3D G3DSA:3.40.1700.10 140 266 1.9E-14 T 23-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily A3L04_08720 8b8a5f918cd0d5e9fb8f3448c15ae5f6 268 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 131 255 1.4E-20 T 23-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal A3L04_08720 8b8a5f918cd0d5e9fb8f3448c15ae5f6 268 SUPERFAMILY SSF143597 110 259 5.1E-29 T 23-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily A3L04_02480 fd5e3dbff00b75e528f9bc3e066d6151 761 Pfam PF10131 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein 85 625 1.0E-39 T 23-10-2018 IPR018776 Membrane protein, 6-pyruvoyl-tetrahydropterin synthase-related domain A3L04_03885 15b184c2d2ee1f607a2f94d6795a2e3d 205 Gene3D G3DSA:3.40.50.11570 1 204 7.4E-42 T 23-10-2018 A3L04_03885 15b184c2d2ee1f607a2f94d6795a2e3d 205 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 5 201 1.4E-42 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L04_03365 c6d346cd76d3ada5381da28cbd2bc8d7 282 Gene3D G3DSA:3.10.580.10 1 121 2.6E-47 T 23-10-2018 A3L04_03365 c6d346cd76d3ada5381da28cbd2bc8d7 282 SUPERFAMILY SSF54631 1 117 2.65E-31 T 23-10-2018 A3L04_03365 c6d346cd76d3ada5381da28cbd2bc8d7 282 SMART SM00116 135 183 1.2 T 23-10-2018 IPR000644 CBS domain A3L04_03365 c6d346cd76d3ada5381da28cbd2bc8d7 282 SMART SM00116 69 117 1.7E-11 T 23-10-2018 IPR000644 CBS domain A3L04_03365 c6d346cd76d3ada5381da28cbd2bc8d7 282 SMART SM00116 10 58 4.9E-8 T 23-10-2018 IPR000644 CBS domain A3L04_03365 c6d346cd76d3ada5381da28cbd2bc8d7 282 SMART SM00116 230 278 2.5E-10 T 23-10-2018 IPR000644 CBS domain A3L04_03365 c6d346cd76d3ada5381da28cbd2bc8d7 282 Pfam PF00571 CBS domain 138 180 4.0E-7 T 23-10-2018 IPR000644 CBS domain A3L04_03365 c6d346cd76d3ada5381da28cbd2bc8d7 282 Pfam PF00571 CBS domain 223 278 2.6E-12 T 23-10-2018 IPR000644 CBS domain A3L04_03365 c6d346cd76d3ada5381da28cbd2bc8d7 282 Pfam PF00571 CBS domain 3 54 4.7E-11 T 23-10-2018 IPR000644 CBS domain A3L04_03365 c6d346cd76d3ada5381da28cbd2bc8d7 282 Pfam PF00571 CBS domain 67 115 6.8E-14 T 23-10-2018 IPR000644 CBS domain A3L04_03365 c6d346cd76d3ada5381da28cbd2bc8d7 282 SUPERFAMILY SSF54631 123 277 3.71E-32 T 23-10-2018 A3L04_09465 ad5d481967b20ac591aaf8b20b94f906 203 SUPERFAMILY SSF55261 87 201 1.07E-40 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A3L04_09465 ad5d481967b20ac591aaf8b20b94f906 203 Gene3D G3DSA:1.10.10.10 4 87 3.3E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_09465 ad5d481967b20ac591aaf8b20b94f906 203 Pfam PF14544 Domain of unknown function (DUF4443) 94 193 6.7E-42 T 23-10-2018 IPR029349 Domain of unknown function DUF4443 A3L04_09465 ad5d481967b20ac591aaf8b20b94f906 203 Gene3D G3DSA:3.30.1360.30 88 194 5.9E-48 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A3L04_09465 ad5d481967b20ac591aaf8b20b94f906 203 SUPERFAMILY SSF46785 24 83 1.05E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_05035 c547ea2d7fba7c0f5fb285c5047c4b09 836 Gene3D G3DSA:3.40.50.2000 268 415 3.8E-16 T 23-10-2018 A3L04_05035 c547ea2d7fba7c0f5fb285c5047c4b09 836 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 590 602 - T 23-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L04_05035 c547ea2d7fba7c0f5fb285c5047c4b09 836 Gene3D G3DSA:3.40.50.2000 416 721 1.2E-42 T 23-10-2018 A3L04_05035 c547ea2d7fba7c0f5fb285c5047c4b09 836 Pfam PF00343 Carbohydrate phosphorylase 126 180 6.4E-6 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L04_05035 c547ea2d7fba7c0f5fb285c5047c4b09 836 Pfam PF00343 Carbohydrate phosphorylase 272 616 1.1E-27 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L04_05035 c547ea2d7fba7c0f5fb285c5047c4b09 836 Pfam PF11897 Protein of unknown function (DUF3417) 15 122 1.4E-32 T 23-10-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A3L04_05035 c547ea2d7fba7c0f5fb285c5047c4b09 836 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 109 696 2.6E-262 T 23-10-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A3L04_05035 c547ea2d7fba7c0f5fb285c5047c4b09 836 PIRSF PIRSF000460 1 772 6.4E-285 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L04_05035 c547ea2d7fba7c0f5fb285c5047c4b09 836 SUPERFAMILY SSF53756 15 730 5.5E-210 T 23-10-2018 A3L04_05035 c547ea2d7fba7c0f5fb285c5047c4b09 836 Gene3D G3DSA:3.40.50.2000 115 190 5.8E-12 T 23-10-2018 A3L04_06685 7ce7fea093876a19f15513d506528e37 152 Pfam PF10015 Uncharacterized protein conserved in archaea (DUF2258) 4 74 7.1E-22 T 23-10-2018 IPR017140 Uncharacterised conserved protein UCP037214 A3L04_05910 ea7767850d71b6b2ab54c89729070b93 146 Pfam PF01750 Hydrogenase maturation protease 32 143 1.3E-20 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L04_05910 ea7767850d71b6b2ab54c89729070b93 146 Gene3D G3DSA:3.40.50.1450 1 146 1.4E-34 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L04_05910 ea7767850d71b6b2ab54c89729070b93 146 SUPERFAMILY SSF53163 1 144 1.8E-28 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L04_05910 ea7767850d71b6b2ab54c89729070b93 146 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 4 143 1.5E-29 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L04_00485 7813cb627e8774243e176afe762d347d 277 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 7 273 3.6E-101 T 23-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 A3L04_00485 7813cb627e8774243e176afe762d347d 277 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 104 272 3.5E-51 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 A3L04_00485 7813cb627e8774243e176afe762d347d 277 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 16 102 2.3E-32 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A3L04_00485 7813cb627e8774243e176afe762d347d 277 Gene3D G3DSA:3.90.1170.20 9 271 1.3E-93 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 A3L04_00485 7813cb627e8774243e176afe762d347d 277 SUPERFAMILY SSF54675 5 103 5.89E-32 T 23-10-2018 A3L04_00485 7813cb627e8774243e176afe762d347d 277 SUPERFAMILY SSF51690 104 273 1.41E-48 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A3L04_00485 7813cb627e8774243e176afe762d347d 277 PIRSF PIRSF006250 3 275 1.7E-94 T 23-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 A3L04_00485 7813cb627e8774243e176afe762d347d 277 Gene3D G3DSA:3.20.20.70 120 263 1.3E-93 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_06700 91b87845a08f3f76554f7d049d85eca9 99 Pfam PF04930 FUN14 family 12 96 5.5E-13 T 23-10-2018 IPR007014 FUN14 A3L04_10630 68cbba9e7bb696b2e17097efd2913e99 135 SMART SM00670 3 121 0.0032 T 23-10-2018 IPR002716 PIN domain A3L04_10630 68cbba9e7bb696b2e17097efd2913e99 135 Pfam PF01850 PIN domain 6 124 3.1E-15 T 23-10-2018 IPR002716 PIN domain A3L04_10630 68cbba9e7bb696b2e17097efd2913e99 135 SUPERFAMILY SSF88723 5 131 7.85E-20 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_10630 68cbba9e7bb696b2e17097efd2913e99 135 Gene3D G3DSA:3.40.50.1010 3 134 1.6E-15 T 23-10-2018 A3L04_04675 2bf4e544cb9245b89a03cf09e2bec05c 150 Pfam PF09638 Ph1570 protein 1 150 8.0E-66 T 23-10-2018 IPR023110 PH1570-like domain A3L04_04675 2bf4e544cb9245b89a03cf09e2bec05c 150 Gene3D G3DSA:3.40.1600.10 1 150 7.8E-72 T 23-10-2018 IPR036807 PH1570-like superfamily A3L04_04675 2bf4e544cb9245b89a03cf09e2bec05c 150 SUPERFAMILY SSF159902 1 150 1.07E-68 T 23-10-2018 A3L04_07835 aa7e65e7806b41acc22be8a4321b1093 346 Hamap MF_00497_A Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 3 346 46.632 T 23-10-2018 IPR023002 Glycerol-1-phosphate dehydrogenase, archaea GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A3L04_07835 aa7e65e7806b41acc22be8a4321b1093 346 Gene3D G3DSA:1.20.1090.10 156 345 2.2E-65 T 23-10-2018 A3L04_07835 aa7e65e7806b41acc22be8a4321b1093 346 SUPERFAMILY SSF56796 2 339 3.66E-71 T 23-10-2018 A3L04_07835 aa7e65e7806b41acc22be8a4321b1093 346 Pfam PF13685 Iron-containing alcohol dehydrogenase 12 268 7.8E-74 T 23-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A3L04_07835 aa7e65e7806b41acc22be8a4321b1093 346 PIRSF PIRSF000112 1 343 4.6E-65 T 23-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A3L04_07835 aa7e65e7806b41acc22be8a4321b1093 346 Gene3D G3DSA:3.40.50.1970 1 155 1.4E-34 T 23-10-2018 A3L04_00415 f18ecfdae1fe5b23134b147c573a7462 373 ProSitePatterns PS01134 FtsZ protein signature 1. 74 108 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A3L04_00415 f18ecfdae1fe5b23134b147c573a7462 373 SUPERFAMILY SSF52490 38 235 6.54E-71 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L04_00415 f18ecfdae1fe5b23134b147c573a7462 373 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 31 363 5.4E-137 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A3L04_00415 f18ecfdae1fe5b23134b147c573a7462 373 Gene3D G3DSA:3.30.1330.20 254 367 1.5E-35 T 23-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 A3L04_00415 f18ecfdae1fe5b23134b147c573a7462 373 SUPERFAMILY SSF55307 233 348 2.75E-38 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A3L04_00415 f18ecfdae1fe5b23134b147c573a7462 373 SMART SM00865 236 352 1.2E-45 T 23-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 A3L04_00415 f18ecfdae1fe5b23134b147c573a7462 373 ProSitePatterns PS01135 FtsZ protein signature 2. 127 148 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A3L04_00415 f18ecfdae1fe5b23134b147c573a7462 373 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 39 363 38.294 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A3L04_00415 f18ecfdae1fe5b23134b147c573a7462 373 SMART SM00864 43 234 2.1E-109 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L04_00415 f18ecfdae1fe5b23134b147c573a7462 373 PRINTS PR00423 Cell division protein FtsZ signature 128 148 5.3E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L04_00415 f18ecfdae1fe5b23134b147c573a7462 373 PRINTS PR00423 Cell division protein FtsZ signature 218 240 5.3E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L04_00415 f18ecfdae1fe5b23134b147c573a7462 373 PRINTS PR00423 Cell division protein FtsZ signature 156 177 5.3E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L04_00415 f18ecfdae1fe5b23134b147c573a7462 373 PRINTS PR00423 Cell division protein FtsZ signature 241 262 5.3E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L04_00415 f18ecfdae1fe5b23134b147c573a7462 373 Pfam PF12327 FtsZ family, C-terminal domain 251 343 2.3E-32 T 23-10-2018 IPR024757 Cell division protein FtsZ, C-terminal A3L04_00415 f18ecfdae1fe5b23134b147c573a7462 373 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 43 203 5.0E-47 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L04_00415 f18ecfdae1fe5b23134b147c573a7462 373 Gene3D G3DSA:3.40.50.1440 34 249 5.1E-84 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L04_03670 efd0d0f2eaae7fa43ba929227354a1d0 193 SUPERFAMILY SSF52317 2 192 9.17E-53 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L04_03670 efd0d0f2eaae7fa43ba929227354a1d0 193 Gene3D G3DSA:3.40.50.880 1 193 1.1E-70 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L04_03670 efd0d0f2eaae7fa43ba929227354a1d0 193 PIRSF PIRSF000495 2 193 4.1E-66 T 23-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A3L04_03670 efd0d0f2eaae7fa43ba929227354a1d0 193 Pfam PF00117 Glutamine amidotransferase class-I 36 190 1.8E-23 T 23-10-2018 IPR017926 Glutamine amidotransferase A3L04_03670 efd0d0f2eaae7fa43ba929227354a1d0 193 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 192 8.3E-70 T 23-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A3L04_03670 efd0d0f2eaae7fa43ba929227354a1d0 193 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 193 36.238 T 23-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A3L04_09745 6b61ae1bb1516a3821e9ab0e37bb656f 248 Pfam PF03029 Conserved hypothetical ATP binding protein 6 242 2.7E-57 T 23-10-2018 IPR004130 GPN-loop GTPase A3L04_09745 6b61ae1bb1516a3821e9ab0e37bb656f 248 SUPERFAMILY SSF52540 1 240 5.11E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09745 6b61ae1bb1516a3821e9ab0e37bb656f 248 Gene3D G3DSA:3.40.50.300 1 244 6.8E-66 T 23-10-2018 A3L04_03775 4d8beec0ef329179b9e71f8b466ff3f9 380 Gene3D G3DSA:3.30.499.10 235 378 1.6E-54 T 23-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 A3L04_03775 4d8beec0ef329179b9e71f8b466ff3f9 380 SUPERFAMILY SSF53732 10 377 2.09E-106 T 23-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 A3L04_03775 4d8beec0ef329179b9e71f8b466ff3f9 380 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 1 379 42.655 T 23-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A3L04_03775 4d8beec0ef329179b9e71f8b466ff3f9 380 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 1 377 4.0E-157 T 23-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A3L04_03775 4d8beec0ef329179b9e71f8b466ff3f9 380 ProSitePatterns PS00450 Aconitase family signature 1. 254 270 - T 23-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A3L04_03775 4d8beec0ef329179b9e71f8b466ff3f9 380 Pfam PF00330 Aconitase family (aconitate hydratase) 16 214 3.6E-31 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A3L04_03775 4d8beec0ef329179b9e71f8b466ff3f9 380 Pfam PF00330 Aconitase family (aconitate hydratase) 218 371 8.7E-34 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A3L04_03775 4d8beec0ef329179b9e71f8b466ff3f9 380 PRINTS PR00415 Aconitase family signature 99 112 1.8E-5 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A3L04_03775 4d8beec0ef329179b9e71f8b466ff3f9 380 PRINTS PR00415 Aconitase family signature 113 128 1.8E-5 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A3L04_03775 4d8beec0ef329179b9e71f8b466ff3f9 380 PRINTS PR00415 Aconitase family signature 186 199 1.8E-5 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A3L04_03775 4d8beec0ef329179b9e71f8b466ff3f9 380 Gene3D G3DSA:3.30.499.20 2 228 1.9E-58 T 23-10-2018 A3L04_03775 4d8beec0ef329179b9e71f8b466ff3f9 380 ProSitePatterns PS01244 Aconitase family signature 2. 312 325 - T 23-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A3L04_06110 d1775a70d6a7c061fc80eba47be19c9c 383 Gene3D G3DSA:1.10.357.20 210 383 7.8E-14 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain A3L04_06110 d1775a70d6a7c061fc80eba47be19c9c 383 Gene3D G3DSA:1.10.357.20 8 184 7.8E-9 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain A3L04_06110 d1775a70d6a7c061fc80eba47be19c9c 383 SUPERFAMILY SSF161093 10 181 8.89E-28 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 A3L04_06110 d1775a70d6a7c061fc80eba47be19c9c 383 SUPERFAMILY SSF161093 214 381 6.67E-26 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 A3L04_06110 d1775a70d6a7c061fc80eba47be19c9c 383 Pfam PF01769 Divalent cation transporter 254 378 8.4E-18 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A3L04_06110 d1775a70d6a7c061fc80eba47be19c9c 383 Pfam PF01769 Divalent cation transporter 53 176 1.6E-18 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A3L04_01840 ef824dd61658ebdf7298e978581a7b0e 208 Gene3D G3DSA:1.20.58.220 1 117 1.8E-27 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L04_01840 ef824dd61658ebdf7298e978581a7b0e 208 Pfam PF02080 TrkA-C domain 125 192 3.3E-14 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A3L04_01840 ef824dd61658ebdf7298e978581a7b0e 208 SUPERFAMILY SSF109755 6 118 2.49E-18 T 23-10-2018 A3L04_01840 ef824dd61658ebdf7298e978581a7b0e 208 SUPERFAMILY SSF116726 109 192 1.02E-21 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L04_01840 ef824dd61658ebdf7298e978581a7b0e 208 Gene3D G3DSA:3.30.70.1450 118 205 8.0E-26 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L04_01840 ef824dd61658ebdf7298e978581a7b0e 208 Pfam PF01895 PhoU domain 19 101 1.9E-11 T 23-10-2018 IPR026022 PhoU domain A3L04_00350 a89fd7ee49b6627007d5f6b2feb53a80 195 Pfam PF01569 PAP2 superfamily 73 165 6.5E-11 T 23-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A3L04_00350 a89fd7ee49b6627007d5f6b2feb53a80 195 Gene3D G3DSA:1.20.144.10 99 181 4.4E-13 T 23-10-2018 A3L04_00350 a89fd7ee49b6627007d5f6b2feb53a80 195 SUPERFAMILY SSF48317 7 178 3.4E-26 T 23-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily A3L04_00350 a89fd7ee49b6627007d5f6b2feb53a80 195 SMART SM00014 73 169 2.8E-6 T 23-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A3L04_10145 049e6e23e36e09b00f69529003a80f0a 321 Gene3D G3DSA:3.40.640.10 30 232 4.2E-70 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L04_10145 049e6e23e36e09b00f69529003a80f0a 321 Gene3D G3DSA:3.90.1150.10 19 315 4.2E-70 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L04_10145 049e6e23e36e09b00f69529003a80f0a 321 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 187 196 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A3L04_10145 049e6e23e36e09b00f69529003a80f0a 321 Pfam PF00155 Aminotransferase class I and II 24 313 6.4E-32 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L04_10145 049e6e23e36e09b00f69529003a80f0a 321 SUPERFAMILY SSF53383 9 317 1.81E-56 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L04_06130 b45db42357ae0a94372eee6110584731 476 PIRSF PIRSF006603 2 476 2.5E-147 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L04_06130 b45db42357ae0a94372eee6110584731 476 TIGRFAM TIGR00797 matE: MATE efflux family protein 28 415 3.0E-75 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L04_06130 b45db42357ae0a94372eee6110584731 476 Pfam PF01554 MatE 249 410 1.0E-26 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L04_06130 b45db42357ae0a94372eee6110584731 476 Pfam PF01554 MatE 28 188 8.1E-30 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L04_00275 7e9ddfecc70ec185b0ff657760ed275f 116 SUPERFAMILY SSF53706 3 53 3.28E-7 T 23-10-2018 A3L04_00275 7e9ddfecc70ec185b0ff657760ed275f 116 SUPERFAMILY SSF160148 48 115 1.15E-19 T 23-10-2018 IPR036593 CPE0013-like superfamily A3L04_00275 7e9ddfecc70ec185b0ff657760ed275f 116 Gene3D G3DSA:3.10.530.10 48 114 1.9E-16 T 23-10-2018 IPR036593 CPE0013-like superfamily A3L04_00275 7e9ddfecc70ec185b0ff657760ed275f 116 Pfam PF07892 Protein of unknown function (DUF1667) 36 114 3.6E-27 T 23-10-2018 IPR012460 Protein of unknown function DUF1667 A3L04_07525 10f04514de57466591675b8831a34f1d 174 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 84 126 1.0E-17 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07525 10f04514de57466591675b8831a34f1d 174 Gene3D G3DSA:3.30.460.80 6 130 9.7E-24 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07525 10f04514de57466591675b8831a34f1d 174 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 33 154 2.3E-25 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07525 10f04514de57466591675b8831a34f1d 174 SUPERFAMILY SSF143243 22 164 4.97E-33 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_02275 02fef336a6f1dfe942ec6808bbefd2e3 468 SMART SM00881 8 106 6.3E-38 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L04_02275 02fef336a6f1dfe942ec6808bbefd2e3 468 SUPERFAMILY SSF51735 5 134 2.43E-36 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_02275 02fef336a6f1dfe942ec6808bbefd2e3 468 SUPERFAMILY SSF52210 303 461 7.98E-37 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L04_02275 02fef336a6f1dfe942ec6808bbefd2e3 468 Pfam PF13380 CoA binding domain 12 138 1.4E-22 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L04_02275 02fef336a6f1dfe942ec6808bbefd2e3 468 Gene3D G3DSA:3.40.50.261 135 299 2.1E-60 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L04_02275 02fef336a6f1dfe942ec6808bbefd2e3 468 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 160 296 5.2E-57 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L04_02275 02fef336a6f1dfe942ec6808bbefd2e3 468 Gene3D G3DSA:3.40.50.261 300 466 1.1E-46 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L04_02275 02fef336a6f1dfe942ec6808bbefd2e3 468 Gene3D G3DSA:3.40.50.720 3 133 9.8E-44 T 23-10-2018 A3L04_02275 02fef336a6f1dfe942ec6808bbefd2e3 468 SUPERFAMILY SSF52210 135 297 2.75E-42 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L04_00955 afc814a4c4b654fd0fe5346c80fe5501 146 Pfam PF04191 Phospholipid methyltransferase 62 131 2.5E-9 T 23-10-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 A3L04_00955 afc814a4c4b654fd0fe5346c80fe5501 146 Gene3D G3DSA:1.20.120.1630 1 142 3.0E-21 T 23-10-2018 A3L04_09000 6656b2679f6aefc8c3b46727eac05918 367 PIRSF PIRSF001434 1 367 1.4E-130 T 23-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A3L04_09000 6656b2679f6aefc8c3b46727eac05918 367 Gene3D G3DSA:3.90.1150.10 230 365 2.5E-45 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L04_09000 6656b2679f6aefc8c3b46727eac05918 367 SUPERFAMILY SSF53383 9 364 7.66E-103 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L04_09000 6656b2679f6aefc8c3b46727eac05918 367 Gene3D G3DSA:3.40.640.10 1 229 5.9E-72 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L04_09000 6656b2679f6aefc8c3b46727eac05918 367 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 364 2.1E-113 T 23-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A3L04_08025 930523d523f022daa3ec5cdc637d3346 288 Pfam PF00146 NADH dehydrogenase 5 284 9.0E-45 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_08025 930523d523f022daa3ec5cdc637d3346 288 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 179 192 - T 23-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_10770 4f5cc35feba2e3cca76683ce5ad938ba 84 Gene3D G3DSA:1.10.10.10 5 73 4.4E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_10770 4f5cc35feba2e3cca76683ce5ad938ba 84 SUPERFAMILY SSF46785 9 73 5.66E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_10770 4f5cc35feba2e3cca76683ce5ad938ba 84 Pfam PF09339 IclR helix-turn-helix domain 11 54 2.0E-9 T 23-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A3L04_10285 09a11ca44548b54e706c322e17e7d5bd 351 Pfam PF00535 Glycosyl transferase family 2 40 199 1.4E-37 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L04_10285 09a11ca44548b54e706c322e17e7d5bd 351 SUPERFAMILY SSF53448 36 296 1.99E-56 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_10285 09a11ca44548b54e706c322e17e7d5bd 351 Gene3D G3DSA:3.90.550.10 30 241 7.7E-45 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_08960 321a1d15b4e10076734d2c8543892459 263 SUPERFAMILY SSF56770 4 210 1.7E-45 T 23-10-2018 A3L04_08960 321a1d15b4e10076734d2c8543892459 263 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 16 150 4.4E-27 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_08960 321a1d15b4e10076734d2c8543892459 263 Gene3D G3DSA:3.40.50.700 4 163 7.1E-43 T 23-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily A3L04_09235 f8791d1d0052860db8ff5db4b93a8dcb 432 Pfam PF00144 Beta-lactamase 3 323 7.9E-65 T 23-10-2018 IPR001466 Beta-lactamase-related A3L04_09235 f8791d1d0052860db8ff5db4b93a8dcb 432 Pfam PF13969 Pab87 octamerisation domain 339 429 2.8E-14 T 23-10-2018 IPR025879 Pab87 octamerisation domain A3L04_09235 f8791d1d0052860db8ff5db4b93a8dcb 432 Gene3D G3DSA:2.40.128.210 337 431 6.9E-29 T 23-10-2018 IPR038164 Pab87 octamerisation domain superfamily A3L04_09235 f8791d1d0052860db8ff5db4b93a8dcb 432 Gene3D G3DSA:3.40.710.10 1 336 1.1E-117 T 23-10-2018 A3L04_09235 f8791d1d0052860db8ff5db4b93a8dcb 432 SUPERFAMILY SSF56601 5 325 9.16E-75 T 23-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A3L04_00980 3421e9ce3641d4f6dd25fe14386e427f 163 Gene3D G3DSA:1.10.1760.20 1 162 7.0E-47 T 23-10-2018 A3L04_00980 3421e9ce3641d4f6dd25fe14386e427f 163 PIRSF PIRSF016661 1 163 8.8E-39 T 23-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A3L04_00980 3421e9ce3641d4f6dd25fe14386e427f 163 Pfam PF02632 BioY family 27 158 1.3E-38 T 23-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A3L04_06660 cc61953b64f1ba2c63c107a2a0ebd41e 139 Pfam PF01986 Domain of unknown function DUF123 25 110 8.7E-21 T 23-10-2018 IPR002837 Protein of unknown function DUF123 A3L04_06660 cc61953b64f1ba2c63c107a2a0ebd41e 139 SMART SM00465 18 113 4.4E-6 T 23-10-2018 IPR000305 GIY-YIG endonuclease A3L04_07955 f2d5f03a069682cd11def5468ed16fc4 593 SUPERFAMILY SSF51445 167 524 5.08E-98 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L04_07955 f2d5f03a069682cd11def5468ed16fc4 593 SUPERFAMILY SSF54556 416 490 5.64E-15 T 23-10-2018 IPR029070 Chitinase insertion domain superfamily A3L04_07955 f2d5f03a069682cd11def5468ed16fc4 593 SMART SM00636 173 519 4.2E-128 T 23-10-2018 IPR011583 Chitinase II GO:0008061 A3L04_07955 f2d5f03a069682cd11def5468ed16fc4 593 ProSitePatterns PS01095 Chitinases family 18 active site. 281 289 - T 23-10-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A3L04_07955 f2d5f03a069682cd11def5468ed16fc4 593 Gene3D G3DSA:3.10.50.10 419 491 7.3E-19 T 23-10-2018 IPR029070 Chitinase insertion domain superfamily A3L04_07955 f2d5f03a069682cd11def5468ed16fc4 593 SUPERFAMILY SSF51055 69 122 8.83E-7 T 23-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A3L04_07955 f2d5f03a069682cd11def5468ed16fc4 593 Pfam PF00704 Glycosyl hydrolases family 18 174 519 4.1E-92 T 23-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 A3L04_07955 f2d5f03a069682cd11def5468ed16fc4 593 Gene3D G3DSA:2.10.10.20 56 126 2.1E-19 T 23-10-2018 A3L04_03955 ca1c75ceeb90f7ec38ef9853d5695ecf 234 PIRSF PIRSF014439 11 234 1.2E-85 T 23-10-2018 IPR016619 Uncharacterised conserved protein UCP014439, ACT A3L04_03955 ca1c75ceeb90f7ec38ef9853d5695ecf 234 Pfam PF13840 ACT domain 164 226 1.3E-9 T 23-10-2018 IPR027795 CASTOR, ACT domain A3L04_03955 ca1c75ceeb90f7ec38ef9853d5695ecf 234 Gene3D G3DSA:3.30.2130.10 93 230 1.3E-9 T 23-10-2018 A3L04_03955 ca1c75ceeb90f7ec38ef9853d5695ecf 234 SUPERFAMILY SSF55021 163 228 2.78E-7 T 23-10-2018 A3L04_00345 47bca4609be9290e6a55ac1f7b4c4a4a 243 SUPERFAMILY SSF88713 35 235 2.28E-16 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L04_00345 47bca4609be9290e6a55ac1f7b4c4a4a 243 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 33 233 9.0E-30 T 23-10-2018 IPR018763 Protein of unknown function DUF2334 A3L04_00345 47bca4609be9290e6a55ac1f7b4c4a4a 243 Gene3D G3DSA:3.20.20.370 38 240 8.5E-15 T 23-10-2018 A3L04_03310 4240fb2108f41522c8264366d73e52b9 472 SUPERFAMILY SSF51735 10 142 3.29E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_03310 4240fb2108f41522c8264366d73e52b9 472 SUPERFAMILY SSF52210 310 466 2.75E-43 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L04_03310 4240fb2108f41522c8264366d73e52b9 472 SMART SM00881 13 112 1.2E-34 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L04_03310 4240fb2108f41522c8264366d73e52b9 472 Gene3D G3DSA:3.40.50.261 308 469 2.0E-52 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L04_03310 4240fb2108f41522c8264366d73e52b9 472 Gene3D G3DSA:3.40.50.261 142 307 1.9E-60 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L04_03310 4240fb2108f41522c8264366d73e52b9 472 Pfam PF13380 CoA binding domain 17 146 4.9E-26 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L04_03310 4240fb2108f41522c8264366d73e52b9 472 Gene3D G3DSA:3.40.50.720 7 141 1.2E-44 T 23-10-2018 A3L04_03310 4240fb2108f41522c8264366d73e52b9 472 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 168 304 5.7E-57 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L04_03310 4240fb2108f41522c8264366d73e52b9 472 SUPERFAMILY SSF52210 144 306 1.31E-44 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L04_05725 ab2662dddbc4e1e013e563ece030285d 109 Pfam PF01588 Putative tRNA binding domain 14 107 2.1E-27 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A3L04_05725 ab2662dddbc4e1e013e563ece030285d 109 SUPERFAMILY SSF50249 8 108 1.86E-31 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_05725 ab2662dddbc4e1e013e563ece030285d 109 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 5 108 1.0E-36 T 23-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L04_05725 ab2662dddbc4e1e013e563ece030285d 109 Gene3D G3DSA:2.40.50.140 2 109 1.6E-36 T 23-10-2018 A3L04_10210 f25e640f7015de97fddf9f9c39b15de2 78 Hamap MF_00794 Putative antitoxin . 2 75 16.672 T 23-10-2018 IPR003847 Putative antitoxin A3L04_10210 f25e640f7015de97fddf9f9c39b15de2 78 ProDom PD188822 UPF0330 AF1997 ST1125.1 AF1689 AF1478 C1_0043 PYRAB04040 PF1222 MM2475 MA1514 3 68 3.0E-20 T 23-10-2018 IPR003847 Putative antitoxin A3L04_10210 f25e640f7015de97fddf9f9c39b15de2 78 Pfam PF02697 Putative antitoxin 3 68 1.1E-20 T 23-10-2018 IPR003847 Putative antitoxin A3L04_01135 5e67116447f5b60c81d9b8c949c42e26 190 SUPERFAMILY SSF56281 7 186 2.49E-41 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_01135 5e67116447f5b60c81d9b8c949c42e26 190 Gene3D G3DSA:3.60.15.10 1 187 1.1E-38 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_01135 5e67116447f5b60c81d9b8c949c42e26 190 Pfam PF00753 Metallo-beta-lactamase superfamily 8 169 4.2E-19 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_01135 5e67116447f5b60c81d9b8c949c42e26 190 SMART SM00849 9 169 2.5E-32 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_01230 8da5d98946e1889428b2e5fa0545da40 241 Gene3D G3DSA:3.40.50.300 2 155 4.2E-26 T 23-10-2018 A3L04_01230 8da5d98946e1889428b2e5fa0545da40 241 Gene3D G3DSA:3.20.20.20 156 211 7.4E-6 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L04_01230 8da5d98946e1889428b2e5fa0545da40 241 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 114 1.7E-16 T 23-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A3L04_01230 8da5d98946e1889428b2e5fa0545da40 241 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 5 118 3.0E-22 T 23-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A3L04_01230 8da5d98946e1889428b2e5fa0545da40 241 SUPERFAMILY SSF52540 1 104 6.11E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01230 8da5d98946e1889428b2e5fa0545da40 241 Pfam PF04060 Putative Fe-S cluster 157 188 4.3E-9 T 23-10-2018 IPR007202 4Fe-4S domain GO:0051536 A3L04_00875 0594cd95232ef6cd41b8760bebb5aa15 328 Gene3D G3DSA:3.40.50.1170 1 198 8.2E-67 T 23-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 A3L04_00875 0594cd95232ef6cd41b8760bebb5aa15 328 PRINTS PR00139 Asparaginase/glutaminase family signature 250 268 6.9E-11 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L04_00875 0594cd95232ef6cd41b8760bebb5aa15 328 PRINTS PR00139 Asparaginase/glutaminase family signature 75 93 6.9E-11 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L04_00875 0594cd95232ef6cd41b8760bebb5aa15 328 PRINTS PR00139 Asparaginase/glutaminase family signature 3 14 6.9E-11 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L04_00875 0594cd95232ef6cd41b8760bebb5aa15 328 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 76 86 - T 23-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 A3L04_00875 0594cd95232ef6cd41b8760bebb5aa15 328 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 4 325 9.6E-90 T 23-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 A3L04_00875 0594cd95232ef6cd41b8760bebb5aa15 328 Pfam PF00710 Asparaginase, N-terminal 4 184 3.7E-55 T 23-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A3L04_00875 0594cd95232ef6cd41b8760bebb5aa15 328 Gene3D G3DSA:3.40.50.40 199 328 1.3E-42 T 23-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 A3L04_00875 0594cd95232ef6cd41b8760bebb5aa15 328 SUPERFAMILY SSF53774 4 326 5.89E-91 T 23-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 A3L04_00875 0594cd95232ef6cd41b8760bebb5aa15 328 PIRSF PIRSF500176 1 322 1.7E-96 T 23-10-2018 A3L04_00875 0594cd95232ef6cd41b8760bebb5aa15 328 PIRSF PIRSF001220 1 324 8.7E-92 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L04_00875 0594cd95232ef6cd41b8760bebb5aa15 328 SMART SM00870 2 313 1.0E-104 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L04_09720 e0aa8bd402a3eb021c6976042f761ac7 385 Pfam PF04412 Protein of unknown function (DUF521) 1 381 4.0E-149 T 23-10-2018 IPR007506 Aconitase X catalytic domain, putative A3L04_00555 b7ddd561ee9ac0c33dbe9029ef178bd3 339 SMART SM00028 93 126 0.0055 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L04_00555 b7ddd561ee9ac0c33dbe9029ef178bd3 339 SMART SM00028 210 243 350.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L04_00555 b7ddd561ee9ac0c33dbe9029ef178bd3 339 SMART SM00028 173 206 31.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L04_00555 b7ddd561ee9ac0c33dbe9029ef178bd3 339 SMART SM00028 54 87 22.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L04_00555 b7ddd561ee9ac0c33dbe9029ef178bd3 339 SMART SM00028 133 166 66.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L04_00555 b7ddd561ee9ac0c33dbe9029ef178bd3 339 Pfam PF13424 Tetratricopeptide repeat 57 121 1.7E-8 T 23-10-2018 A3L04_00555 b7ddd561ee9ac0c33dbe9029ef178bd3 339 Pfam PF13424 Tetratricopeptide repeat 134 201 2.3E-9 T 23-10-2018 A3L04_00555 b7ddd561ee9ac0c33dbe9029ef178bd3 339 Gene3D G3DSA:1.25.40.10 48 317 1.8E-27 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L04_00555 b7ddd561ee9ac0c33dbe9029ef178bd3 339 SUPERFAMILY SSF48452 53 283 4.68E-28 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L04_09340 2609e39c83d2e48ae68223abecc2efa6 314 TIGRFAM TIGR00746 arcC: carbamate kinase 3 313 3.5E-150 T 23-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 A3L04_09340 2609e39c83d2e48ae68223abecc2efa6 314 Gene3D G3DSA:3.40.1160.10 1 313 8.4E-138 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L04_09340 2609e39c83d2e48ae68223abecc2efa6 314 PIRSF PIRSF000723 1 314 9.4E-144 T 23-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 A3L04_09340 2609e39c83d2e48ae68223abecc2efa6 314 SUPERFAMILY SSF53633 3 314 5.24E-88 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L04_09340 2609e39c83d2e48ae68223abecc2efa6 314 PRINTS PR01469 Bacterial carbamate kinase signature 161 180 3.7E-71 T 23-10-2018 A3L04_09340 2609e39c83d2e48ae68223abecc2efa6 314 PRINTS PR01469 Bacterial carbamate kinase signature 214 229 3.7E-71 T 23-10-2018 A3L04_09340 2609e39c83d2e48ae68223abecc2efa6 314 PRINTS PR01469 Bacterial carbamate kinase signature 112 131 3.7E-71 T 23-10-2018 A3L04_09340 2609e39c83d2e48ae68223abecc2efa6 314 PRINTS PR01469 Bacterial carbamate kinase signature 184 202 3.7E-71 T 23-10-2018 A3L04_09340 2609e39c83d2e48ae68223abecc2efa6 314 PRINTS PR01469 Bacterial carbamate kinase signature 269 284 3.7E-71 T 23-10-2018 A3L04_09340 2609e39c83d2e48ae68223abecc2efa6 314 PRINTS PR01469 Bacterial carbamate kinase signature 44 63 3.7E-71 T 23-10-2018 A3L04_09340 2609e39c83d2e48ae68223abecc2efa6 314 PRINTS PR01469 Bacterial carbamate kinase signature 77 95 3.7E-71 T 23-10-2018 A3L04_09340 2609e39c83d2e48ae68223abecc2efa6 314 Pfam PF00696 Amino acid kinase family 3 296 2.4E-32 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A3L04_07420 a8715e99b0a4b686a78504ec746f3be4 380 Pfam PF04055 Radical SAM superfamily 26 180 2.0E-10 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_07420 a8715e99b0a4b686a78504ec746f3be4 380 SUPERFAMILY SSF102114 28 222 8.04E-9 T 23-10-2018 A3L04_07420 a8715e99b0a4b686a78504ec746f3be4 380 Gene3D G3DSA:3.80.30.30 78 236 4.5E-8 T 23-10-2018 A3L04_05210 0ad08e26f2cd2818298df91fe12cc2aa 243 SUPERFAMILY SSF53697 3 203 1.85E-22 T 23-10-2018 A3L04_05210 0ad08e26f2cd2818298df91fe12cc2aa 243 Pfam PF13580 SIS domain 4 139 2.2E-41 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A3L04_05210 0ad08e26f2cd2818298df91fe12cc2aa 243 Gene3D G3DSA:3.40.50.10490 1 239 5.3E-86 T 23-10-2018 A3L04_06630 29b414821b5002ec58e78dd746ac19c8 182 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 8 172 9.8E-56 T 23-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L04_06630 29b414821b5002ec58e78dd746ac19c8 182 SUPERFAMILY SSF53271 3 169 3.15E-51 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L04_06630 29b414821b5002ec58e78dd746ac19c8 182 Pfam PF00156 Phosphoribosyl transferase domain 37 155 5.0E-25 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L04_06630 29b414821b5002ec58e78dd746ac19c8 182 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 182 29.171 T 23-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L04_06630 29b414821b5002ec58e78dd746ac19c8 182 Gene3D G3DSA:3.40.50.2020 1 179 1.5E-64 T 23-10-2018 A3L04_07675 4bbb5a41c646e9e91725f259ad5615bd 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 230 322 1.4E-28 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L04_07675 4bbb5a41c646e9e91725f259ad5615bd 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 300 3.9E-19 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L04_07675 4bbb5a41c646e9e91725f259ad5615bd 326 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_07675 4bbb5a41c646e9e91725f259ad5615bd 326 Pfam PF00005 ABC transporter 31 181 1.4E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_07675 4bbb5a41c646e9e91725f259ad5615bd 326 SUPERFAMILY SSF52540 5 252 4.71E-76 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_07675 4bbb5a41c646e9e91725f259ad5615bd 326 Gene3D G3DSA:3.40.50.300 3 326 1.9E-103 T 23-10-2018 A3L04_07675 4bbb5a41c646e9e91725f259ad5615bd 326 SMART SM00382 39 230 3.5E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_09590 3eb620ee381e071a1e2bb6d1a85ee054 364 SUPERFAMILY SSF47240 14 139 3.48E-14 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L04_09590 3eb620ee381e071a1e2bb6d1a85ee054 364 Pfam PF02915 Rubrerythrin 15 137 1.6E-8 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L04_09590 3eb620ee381e071a1e2bb6d1a85ee054 364 Pfam PF01988 VIT family 148 352 2.2E-42 T 23-10-2018 IPR008217 Ccc1 family A3L04_09590 3eb620ee381e071a1e2bb6d1a85ee054 364 Gene3D G3DSA:1.20.1260.10 12 144 8.4E-7 T 23-10-2018 IPR012347 Ferritin-like A3L04_01695 2252b75cf67bf0b2b32fbfebc8db3ea6 413 Pfam PF00155 Aminotransferase class I and II 62 405 3.4E-39 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L04_01695 2252b75cf67bf0b2b32fbfebc8db3ea6 413 Gene3D G3DSA:3.90.1150.10 32 409 2.1E-163 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L04_01695 2252b75cf67bf0b2b32fbfebc8db3ea6 413 Gene3D G3DSA:3.40.640.10 79 304 2.1E-163 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L04_01695 2252b75cf67bf0b2b32fbfebc8db3ea6 413 SUPERFAMILY SSF53383 16 411 3.71E-119 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L04_06920 bab5b05fab204bde710e10e99cb7b49e 197 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 14 108 3.3E-21 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A3L04_06920 bab5b05fab204bde710e10e99cb7b49e 197 Gene3D G3DSA:3.30.420.130 1 115 1.8E-27 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L04_06920 bab5b05fab204bde710e10e99cb7b49e 197 SUPERFAMILY SSF53146 3 111 1.96E-26 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L04_00550 de62e8c47f0fc4142e14078a3cb7dccd 428 Gene3D G3DSA:3.40.190.10 26 423 2.0E-55 T 23-10-2018 A3L04_00550 de62e8c47f0fc4142e14078a3cb7dccd 428 SUPERFAMILY SSF53850 44 420 4.1E-60 T 23-10-2018 A3L04_00550 de62e8c47f0fc4142e14078a3cb7dccd 428 Pfam PF13416 Bacterial extracellular solute-binding protein 51 349 9.9E-43 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein A3L04_03240 2de756b9f695e023205c9483737f0faa 162 ProSitePatterns PS01318 TsaA-like domain signature. 81 92 - T 23-10-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site A3L04_03240 2de756b9f695e023205c9483737f0faa 162 Pfam PF01980 Uncharacterised protein family UPF0066 21 133 3.9E-39 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain A3L04_03240 2de756b9f695e023205c9483737f0faa 162 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 2 134 2.1E-43 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain A3L04_03240 2de756b9f695e023205c9483737f0faa 162 Gene3D G3DSA:2.40.30.70 5 148 1.3E-48 T 23-10-2018 IPR036414 YaeB, N-terminal domain superfamily A3L04_03240 2de756b9f695e023205c9483737f0faa 162 SUPERFAMILY SSF118196 3 150 1.11E-52 T 23-10-2018 IPR036413 YaeB-like superfamily A3L04_05250 5443d06fcf3afd71971ff1321bb3dfb5 284 SUPERFAMILY SSF46785 205 270 2.66E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_05250 5443d06fcf3afd71971ff1321bb3dfb5 284 Pfam PF13412 Winged helix-turn-helix DNA-binding 231 264 8.9E-8 T 23-10-2018 A3L04_05250 5443d06fcf3afd71971ff1321bb3dfb5 284 Gene3D G3DSA:1.10.10.10 198 276 1.3E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_08575 3dc64b04d80e85343f8a59f079c3d4fe 474 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 155 455 2.4E-42 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L04_08575 3dc64b04d80e85343f8a59f079c3d4fe 474 Gene3D G3DSA:1.10.1060.10 5 148 5.0E-41 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L04_08575 3dc64b04d80e85343f8a59f079c3d4fe 474 Gene3D G3DSA:3.50.50.60 151 288 1.0E-39 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_08575 3dc64b04d80e85343f8a59f079c3d4fe 474 Gene3D G3DSA:3.50.50.60 290 474 2.4E-33 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_08575 3dc64b04d80e85343f8a59f079c3d4fe 474 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 16 470 1.4E-211 T 23-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 A3L04_08575 3dc64b04d80e85343f8a59f079c3d4fe 474 SUPERFAMILY SSF46548 7 165 4.81E-34 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L04_08575 3dc64b04d80e85343f8a59f079c3d4fe 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 295 320 5.2E-16 T 23-10-2018 A3L04_08575 3dc64b04d80e85343f8a59f079c3d4fe 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 178 5.2E-16 T 23-10-2018 A3L04_08575 3dc64b04d80e85343f8a59f079c3d4fe 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 439 446 5.2E-16 T 23-10-2018 A3L04_08575 3dc64b04d80e85343f8a59f079c3d4fe 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 397 411 5.2E-16 T 23-10-2018 A3L04_08575 3dc64b04d80e85343f8a59f079c3d4fe 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 295 313 6.3E-23 T 23-10-2018 A3L04_08575 3dc64b04d80e85343f8a59f079c3d4fe 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 424 446 6.3E-23 T 23-10-2018 A3L04_08575 3dc64b04d80e85343f8a59f079c3d4fe 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 396 412 6.3E-23 T 23-10-2018 A3L04_08575 3dc64b04d80e85343f8a59f079c3d4fe 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 176 6.3E-23 T 23-10-2018 A3L04_08575 3dc64b04d80e85343f8a59f079c3d4fe 474 SUPERFAMILY SSF51971 153 405 5.83E-75 T 23-10-2018 A3L04_08575 3dc64b04d80e85343f8a59f079c3d4fe 474 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 19 137 1.1E-38 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A3L04_06420 3fd909fe9afbe0e19aaf34a88584e43f 470 SUPERFAMILY SSF52540 41 428 1.03E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_06420 3fd909fe9afbe0e19aaf34a88584e43f 470 Pfam PF01935 Domain of unknown function DUF87 200 320 8.0E-9 T 23-10-2018 IPR002789 Helicase HerA, central domain A3L04_06420 3fd909fe9afbe0e19aaf34a88584e43f 470 Gene3D G3DSA:3.40.50.300 291 467 7.6E-11 T 23-10-2018 A3L04_00385 1213066508e6ee84c98057034d9a279b 107 Gene3D G3DSA:1.10.10.1410 1 58 1.9E-31 T 23-10-2018 IPR038716 Ribosomal protein P1/P2, N-terminal domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_00385 1213066508e6ee84c98057034d9a279b 107 TIGRFAM TIGR03685 ribo_P1_arch: 50S ribosomal protein P1 1 107 3.8E-43 T 23-10-2018 IPR022295 Ribosomal protein L12, archaea GO:0003735|GO:0005840|GO:0006414 A3L04_00385 1213066508e6ee84c98057034d9a279b 107 Pfam PF00428 60s Acidic ribosomal protein 16 106 3.6E-19 T 23-10-2018 A3L04_00385 1213066508e6ee84c98057034d9a279b 107 Hamap MF_01478 50S ribosomal protein L12 [rpl12]. 1 104 14.654 T 23-10-2018 IPR027534 Ribosomal protein L12 family GO:0003735|GO:0005622|GO:0005840|GO:0006414 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_05580 f7291ef4643df3b8307a4f54e30e2c95 330 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 1 308 1.7E-113 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A3L04_05580 f7291ef4643df3b8307a4f54e30e2c95 330 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 24 281 2.5E-83 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A3L04_05580 f7291ef4643df3b8307a4f54e30e2c95 330 Gene3D G3DSA:2.40.100.10 169 310 1.2E-49 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A3L04_05580 f7291ef4643df3b8307a4f54e30e2c95 330 SMART SM00797 23 298 1.8E-138 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A3L04_05580 f7291ef4643df3b8307a4f54e30e2c95 330 SUPERFAMILY SSF50891 172 287 1.29E-11 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A3L04_02875 aba14f420c35cd28b46387af19504231 748 Gene3D G3DSA:1.20.1480.50 308 402 1.3E-6 T 23-10-2018 A3L04_02875 aba14f420c35cd28b46387af19504231 748 SMART SM00283 472 740 2.7E-62 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A3L04_02875 aba14f420c35cd28b46387af19504231 748 Gene3D G3DSA:1.10.287.950 446 747 9.7E-66 T 23-10-2018 A3L04_02875 aba14f420c35cd28b46387af19504231 748 Gene3D G3DSA:3.30.450.20 173 307 1.7E-31 T 23-10-2018 A3L04_02875 aba14f420c35cd28b46387af19504231 748 Pfam PF02743 Cache domain 48 291 6.6E-42 T 23-10-2018 IPR033479 Double Cache domain 1 A3L04_02875 aba14f420c35cd28b46387af19504231 748 Pfam PF00672 HAMP domain 342 389 1.8E-6 T 23-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A3L04_02875 aba14f420c35cd28b46387af19504231 748 SUPERFAMILY SSF58104 503 747 4.19E-59 T 23-10-2018 A3L04_02875 aba14f420c35cd28b46387af19504231 748 SUPERFAMILY SSF103190 115 210 2.94E-17 T 23-10-2018 IPR029151 Periplasmic sensor-like domain superfamily A3L04_02875 aba14f420c35cd28b46387af19504231 748 SMART SM00304 340 398 0.013 T 23-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A3L04_02875 aba14f420c35cd28b46387af19504231 748 SMART SM00304 399 443 35.0 T 23-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A3L04_02875 aba14f420c35cd28b46387af19504231 748 SMART SM00304 688 744 74.0 T 23-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A3L04_02875 aba14f420c35cd28b46387af19504231 748 SUPERFAMILY SSF58104 417 527 7.19E-9 T 23-10-2018 A3L04_02875 aba14f420c35cd28b46387af19504231 748 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 525 678 8.6E-39 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A3L04_03845 04aa63168a6b7b4fbad9978443fb19f4 212 Pfam PF01487 Type I 3-dehydroquinase 6 207 1.4E-52 T 23-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A3L04_03845 04aa63168a6b7b4fbad9978443fb19f4 212 SUPERFAMILY SSF51569 2 211 5.13E-55 T 23-10-2018 A3L04_03845 04aa63168a6b7b4fbad9978443fb19f4 212 Gene3D G3DSA:3.20.20.70 1 210 8.1E-55 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_03845 04aa63168a6b7b4fbad9978443fb19f4 212 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 1 210 33.447 T 23-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A3L04_03845 04aa63168a6b7b4fbad9978443fb19f4 212 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 4 207 9.9E-45 T 23-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A3L04_05655 b87bed3918893c987c3898e0f2724263 343 Pfam PF01032 FecCD transport family 19 338 7.5E-93 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A3L04_05655 b87bed3918893c987c3898e0f2724263 343 SUPERFAMILY SSF81345 5 338 3.4E-81 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L04_05655 b87bed3918893c987c3898e0f2724263 343 Gene3D G3DSA:1.10.3470.10 6 342 1.0E-98 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L04_07390 81a855de2b99bee62ebff41bd8c7cc31 108 Gene3D G3DSA:1.10.10.10 4 107 8.4E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_07390 81a855de2b99bee62ebff41bd8c7cc31 108 Pfam PF03551 Transcriptional regulator PadR-like family 21 93 5.8E-18 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L04_07390 81a855de2b99bee62ebff41bd8c7cc31 108 SUPERFAMILY SSF46785 17 101 6.94E-21 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_10270 5cca11c73ce1c58edfdcba02ea764818 186 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 67 89 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A3L04_10270 5cca11c73ce1c58edfdcba02ea764818 186 Pfam PF01066 CDP-alcohol phosphatidyltransferase 25 89 3.3E-14 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A3L04_10270 5cca11c73ce1c58edfdcba02ea764818 186 Gene3D G3DSA:1.20.120.1760 6 186 1.3E-51 T 23-10-2018 A3L04_01570 5b6c0815c204e8ece26a01af194ec9ec 226 SUPERFAMILY SSF52833 5 117 1.42E-25 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L04_01570 5b6c0815c204e8ece26a01af194ec9ec 226 TIGRFAM TIGR02187 GlrX_arch: glutaredoxin-like domain protein 4 223 2.5E-91 T 23-10-2018 IPR011903 Glutaredoxin-like domain A3L04_01570 5b6c0815c204e8ece26a01af194ec9ec 226 SUPERFAMILY SSF52833 121 221 6.78E-22 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L04_01570 5b6c0815c204e8ece26a01af194ec9ec 226 Gene3D G3DSA:3.40.30.10 120 225 9.3E-28 T 23-10-2018 A3L04_01570 5b6c0815c204e8ece26a01af194ec9ec 226 Pfam PF13192 Thioredoxin domain 137 222 4.6E-15 T 23-10-2018 IPR012336 Thioredoxin-like fold A3L04_01570 5b6c0815c204e8ece26a01af194ec9ec 226 Gene3D G3DSA:3.40.30.10 1 117 2.0E-38 T 23-10-2018 A3L04_01570 5b6c0815c204e8ece26a01af194ec9ec 226 Pfam PF00085 Thioredoxin 12 98 4.3E-5 T 23-10-2018 IPR013766 Thioredoxin domain GO:0045454 A3L04_06655 435b508ba0b1623ff7787365e2760182 253 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 21 235 1.8E-79 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A3L04_06655 435b508ba0b1623ff7787365e2760182 253 Gene3D G3DSA:3.20.20.390 4 250 1.9E-102 T 23-10-2018 IPR038597 GGGP/HepGP synthase superfamily A3L04_06655 435b508ba0b1623ff7787365e2760182 253 SUPERFAMILY SSF51395 18 240 4.76E-49 T 23-10-2018 A3L04_06655 435b508ba0b1623ff7787365e2760182 253 TIGRFAM TIGR01769 GGGP: phosphoglycerol geranylgeranyltransferase 22 228 2.3E-86 T 23-10-2018 IPR010946 Geranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005737|GO:0006650|GO:0047294 KEGG: 00564+2.5.1.41|MetaCyc: PWY-6349 A3L04_06655 435b508ba0b1623ff7787365e2760182 253 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 15 253 35.653 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A3L04_06655 435b508ba0b1623ff7787365e2760182 253 Pfam PF01884 PcrB family 18 235 5.1E-69 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A3L04_06905 44bb8262a80e2ee5b11a9be70adbd54f 160 Pfam PF03773 Predicted permease 28 158 2.9E-12 T 23-10-2018 IPR005524 Predicted permease DUF318 A3L04_05240 342dce4222b67e1e3a160d73dbe151c4 372 Pfam PF01170 Putative RNA methylase family UPF0020 181 324 2.2E-12 T 23-10-2018 IPR000241 Putative RNA methylase domain A3L04_05240 342dce4222b67e1e3a160d73dbe151c4 372 SUPERFAMILY SSF53335 179 345 3.8E-21 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_05240 342dce4222b67e1e3a160d73dbe151c4 372 Gene3D G3DSA:3.40.50.150 172 359 5.7E-29 T 23-10-2018 A3L04_10805 1f031fbe012cd670101c273739135580 190 Pfam PF13238 AAA domain 3 137 3.4E-20 T 23-10-2018 A3L04_10805 1f031fbe012cd670101c273739135580 190 SUPERFAMILY SSF52540 1 187 7.43E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_10805 1f031fbe012cd670101c273739135580 190 Gene3D G3DSA:3.40.50.300 1 189 9.9E-39 T 23-10-2018 A3L04_05745 016e7b22a8b1be2ab5f6cd4f4185f701 331 SUPERFAMILY SSF52540 12 322 1.37E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_05745 016e7b22a8b1be2ab5f6cd4f4185f701 331 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 15 323 6.4E-72 T 23-10-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 A3L04_05745 016e7b22a8b1be2ab5f6cd4f4185f701 331 Pfam PF02374 Anion-transporting ATPase 12 327 1.6E-70 T 23-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 A3L04_05745 016e7b22a8b1be2ab5f6cd4f4185f701 331 Gene3D G3DSA:3.40.50.300 3 330 2.5E-86 T 23-10-2018 A3L04_05330 458016c8548379d9c06bee48136c68f0 82 Pfam PF04457 Protein of unknown function (DUF504) 26 77 4.8E-15 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 A3L04_05330 458016c8548379d9c06bee48136c68f0 82 Hamap MF_01245 UPF0248 protein . 10 79 19.262 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 A3L04_10380 7c87e7e7972d553ed1eaf7a5f3554c47 340 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 8 208 2.8E-72 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 A3L04_10380 7c87e7e7972d553ed1eaf7a5f3554c47 340 PIRSF PIRSF004930 1 340 2.0E-134 T 23-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 A3L04_10380 7c87e7e7972d553ed1eaf7a5f3554c47 340 Gene3D G3DSA:3.90.870.10 2 213 3.5E-88 T 23-10-2018 A3L04_10380 7c87e7e7972d553ed1eaf7a5f3554c47 340 Pfam PF03481 Putative GTP-binding controlling metal-binding 201 334 1.2E-26 T 23-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain A3L04_10380 7c87e7e7972d553ed1eaf7a5f3554c47 340 Gene3D G3DSA:3.40.50.11030 236 340 1.7E-38 T 23-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily A3L04_10380 7c87e7e7972d553ed1eaf7a5f3554c47 340 Pfam PF01300 Telomere recombination 22 197 1.4E-61 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 A3L04_10380 7c87e7e7972d553ed1eaf7a5f3554c47 340 SUPERFAMILY SSF55821 9 210 1.01E-69 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A3L04_07460 a8c1366bf3b78e1f6802cb0a3b4873d5 309 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 31 55 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A3L04_07460 a8c1366bf3b78e1f6802cb0a3b4873d5 309 Pfam PF00294 pfkB family carbohydrate kinase 2 288 6.6E-61 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A3L04_07460 a8c1366bf3b78e1f6802cb0a3b4873d5 309 Gene3D G3DSA:3.40.1190.20 1 308 2.5E-112 T 23-10-2018 IPR029056 Ribokinase-like A3L04_07460 a8c1366bf3b78e1f6802cb0a3b4873d5 309 PRINTS PR00990 Ribokinase signature 26 45 8.8E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L04_07460 a8c1366bf3b78e1f6802cb0a3b4873d5 309 PRINTS PR00990 Ribokinase signature 179 194 8.8E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L04_07460 a8c1366bf3b78e1f6802cb0a3b4873d5 309 PRINTS PR00990 Ribokinase signature 210 221 8.8E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L04_07460 a8c1366bf3b78e1f6802cb0a3b4873d5 309 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 239 252 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A3L04_07460 a8c1366bf3b78e1f6802cb0a3b4873d5 309 SUPERFAMILY SSF53613 2 298 3.27E-72 T 23-10-2018 IPR029056 Ribokinase-like A3L04_05070 e4f195dd0935d457f02630c1700b4662 456 Pfam PF06745 KaiC 6 222 4.3E-62 T 23-10-2018 IPR014774 KaiC-like domain A3L04_05070 e4f195dd0935d457f02630c1700b4662 456 Pfam PF06745 KaiC 240 456 2.6E-39 T 23-10-2018 IPR014774 KaiC-like domain A3L04_05070 e4f195dd0935d457f02630c1700b4662 456 SUPERFAMILY SSF52540 13 223 3.55E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_05070 e4f195dd0935d457f02630c1700b4662 456 Gene3D G3DSA:3.40.50.300 4 227 8.0E-50 T 23-10-2018 A3L04_05070 e4f195dd0935d457f02630c1700b4662 456 SUPERFAMILY SSF52540 237 455 1.37E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_05070 e4f195dd0935d457f02630c1700b4662 456 Gene3D G3DSA:3.40.50.300 236 456 2.4E-57 T 23-10-2018 A3L04_05070 e4f195dd0935d457f02630c1700b4662 456 SMART SM00382 21 173 0.25 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_05070 e4f195dd0935d457f02630c1700b4662 456 SMART SM00382 257 434 7.9E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_05070 e4f195dd0935d457f02630c1700b4662 456 PRINTS PR01874 DNA repair protein radA signature 291 308 1.8E-7 T 23-10-2018 A3L04_05070 e4f195dd0935d457f02630c1700b4662 456 PRINTS PR01874 DNA repair protein radA signature 249 277 1.8E-7 T 23-10-2018 A3L04_05070 e4f195dd0935d457f02630c1700b4662 456 PIRSF PIRSF039117 4 456 2.2E-118 T 23-10-2018 IPR030665 Circadian clock protein kinase KaiC KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 A3L04_02190 bacb57edf96b1f0ccbf70ac612d34ae4 246 PIRSF PIRSF006601 1 246 1.2E-107 T 23-10-2018 IPR012096 ATPase, PP-loop, MJ1638-related A3L04_02190 bacb57edf96b1f0ccbf70ac612d34ae4 246 Gene3D G3DSA:3.40.50.620 41 167 8.7E-9 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_02190 bacb57edf96b1f0ccbf70ac612d34ae4 246 SUPERFAMILY SSF52402 55 188 8.38E-15 T 23-10-2018 A3L04_07560 88cafd5dbb6561a9c35b8a3881e6e084 141 Gene3D G3DSA:3.30.70.3270 23 141 4.0E-22 T 23-10-2018 A3L04_07560 88cafd5dbb6561a9c35b8a3881e6e084 141 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_07560 88cafd5dbb6561a9c35b8a3881e6e084 141 Pfam PF13187 4Fe-4S dicluster domain 45 91 4.9E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L04_07560 88cafd5dbb6561a9c35b8a3881e6e084 141 SUPERFAMILY SSF54862 27 110 1.47E-22 T 23-10-2018 A3L04_01060 877774fb307bc47475d224cc717cc809 162 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 4 161 6.6E-32 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 A3L04_01060 877774fb307bc47475d224cc717cc809 162 Pfam PF01930 Domain of unknown function DUF83 4 161 5.0E-55 T 23-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 A3L04_01060 877774fb307bc47475d224cc717cc809 162 Gene3D G3DSA:3.90.320.10 1 162 9.0E-10 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal A3L04_02060 a18b9a2faf34a03bb269d9a9a083237b 302 Gene3D G3DSA:3.20.20.70 40 280 1.2E-30 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_02060 a18b9a2faf34a03bb269d9a9a083237b 302 Pfam PF04055 Radical SAM superfamily 61 210 4.7E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_02060 a18b9a2faf34a03bb269d9a9a083237b 302 SMART SM00729 56 253 2.9E-5 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L04_02060 a18b9a2faf34a03bb269d9a9a083237b 302 SUPERFAMILY SSF102114 60 261 6.67E-32 T 23-10-2018 A3L04_03990 abf85efbbd1c902ef959ece52ba97088 166 Gene3D G3DSA:3.40.50.880 1 166 1.7E-54 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L04_03990 abf85efbbd1c902ef959ece52ba97088 166 Pfam PF01965 DJ-1/PfpI family 1 163 1.4E-60 T 23-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A3L04_03990 abf85efbbd1c902ef959ece52ba97088 166 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 3 166 2.0E-69 T 23-10-2018 IPR006286 Deglycase PfpI A3L04_03990 abf85efbbd1c902ef959ece52ba97088 166 SUPERFAMILY SSF52317 1 165 1.43E-53 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L04_05695 527a54a64c43fa57374718d1f355e7a2 229 SUPERFAMILY SSF52540 1 168 3.04E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_05695 527a54a64c43fa57374718d1f355e7a2 229 Pfam PF00005 ABC transporter 1 113 1.2E-11 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_05695 527a54a64c43fa57374718d1f355e7a2 229 Gene3D G3DSA:3.40.50.300 1 181 1.2E-34 T 23-10-2018 A3L04_03860 694658628692023195e3c69ee15a5d12 422 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 54 345 6.6E-46 T 23-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 A3L04_03860 694658628692023195e3c69ee15a5d12 422 SUPERFAMILY SSF53822 69 311 3.66E-7 T 23-10-2018 IPR028082 Periplasmic binding protein-like I A3L04_03860 694658628692023195e3c69ee15a5d12 422 Gene3D G3DSA:3.40.50.2300 58 324 1.6E-72 T 23-10-2018 A3L04_03860 694658628692023195e3c69ee15a5d12 422 Gene3D G3DSA:3.40.50.2300 159 332 1.6E-72 T 23-10-2018 A3L04_03895 cd0d03d5d78ebb2763074e8ed5a2e08b 401 PIRSF PIRSF000505 1 401 9.0E-129 T 23-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A3L04_03895 cd0d03d5d78ebb2763074e8ed5a2e08b 401 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 6 396 1.5E-102 T 23-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A3L04_03895 cd0d03d5d78ebb2763074e8ed5a2e08b 401 ProSitePatterns PS00885 EPSP synthase signature 2. 314 332 - T 23-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A3L04_03895 cd0d03d5d78ebb2763074e8ed5a2e08b 401 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 8 401 31.663 T 23-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A3L04_03895 cd0d03d5d78ebb2763074e8ed5a2e08b 401 Gene3D G3DSA:3.65.10.10 20 222 1.1E-117 T 23-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 A3L04_03895 cd0d03d5d78ebb2763074e8ed5a2e08b 401 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 12 400 1.1E-127 T 23-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A3L04_03895 cd0d03d5d78ebb2763074e8ed5a2e08b 401 Gene3D G3DSA:3.65.10.10 12 392 1.1E-117 T 23-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 A3L04_03895 cd0d03d5d78ebb2763074e8ed5a2e08b 401 SUPERFAMILY SSF55205 2 399 3.53E-107 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A3L04_03120 8f654b875b6379e6e18c55fac4c694ff 379 Gene3D G3DSA:3.40.50.150 1 319 2.0E-109 T 23-10-2018 A3L04_03120 8f654b875b6379e6e18c55fac4c694ff 379 Gene3D G3DSA:3.30.56.70 320 379 8.6E-27 T 23-10-2018 A3L04_03120 8f654b875b6379e6e18c55fac4c694ff 379 Hamap MF_00290 tRNA (guanine(26)-N(2))-dimethyltransferase [trm1]. 4 378 43.794 T 23-10-2018 IPR022923 tRNA (guanine(26)-N(2))-dimethyltransferase, archaeal and bacterial GO:0004809 MetaCyc: PWY-6829 A3L04_03120 8f654b875b6379e6e18c55fac4c694ff 379 Pfam PF02005 N2,N2-dimethylguanosine tRNA methyltransferase 9 377 9.1E-127 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 A3L04_03120 8f654b875b6379e6e18c55fac4c694ff 379 SUPERFAMILY SSF53335 5 377 3.71E-119 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_03120 8f654b875b6379e6e18c55fac4c694ff 379 TIGRFAM TIGR00308 TRM1: N2,N2-dimethylguanosine tRNA methyltransferase 6 378 1.8E-92 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 A3L04_02755 5f3e4bca9045915fcb3339d0a2f2d8a9 211 Gene3D G3DSA:3.90.1490.10 117 209 6.8E-13 T 23-10-2018 A3L04_02755 5f3e4bca9045915fcb3339d0a2f2d8a9 211 Pfam PF01902 Diphthamide synthase 1 207 2.5E-36 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L04_02755 5f3e4bca9045915fcb3339d0a2f2d8a9 211 Gene3D G3DSA:3.40.50.620 1 115 3.6E-14 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_02755 5f3e4bca9045915fcb3339d0a2f2d8a9 211 SUPERFAMILY SSF52402 1 207 1.17E-49 T 23-10-2018 A3L04_02755 5f3e4bca9045915fcb3339d0a2f2d8a9 211 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 1 206 1.1E-34 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L04_08290 6a96159fd5b34378dd873df8dc3e4099 577 Gene3D G3DSA:1.20.1560.10 2 324 1.1E-80 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A3L04_08290 6a96159fd5b34378dd873df8dc3e4099 577 SUPERFAMILY SSF52540 328 571 1.2E-85 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_08290 6a96159fd5b34378dd873df8dc3e4099 577 Pfam PF00664 ABC transporter transmembrane region 22 292 9.1E-48 T 23-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A3L04_08290 6a96159fd5b34378dd873df8dc3e4099 577 SMART SM00382 364 550 1.8E-19 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_08290 6a96159fd5b34378dd873df8dc3e4099 577 ProSitePatterns PS00211 ABC transporters family signature. 476 490 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_08290 6a96159fd5b34378dd873df8dc3e4099 577 Pfam PF00005 ABC transporter 355 503 9.0E-38 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_08290 6a96159fd5b34378dd873df8dc3e4099 577 SUPERFAMILY SSF90123 9 326 3.14E-74 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A3L04_08290 6a96159fd5b34378dd873df8dc3e4099 577 Gene3D G3DSA:3.40.50.300 328 575 2.2E-91 T 23-10-2018 A3L04_05190 c68f5e8369baa5abb9101456c1304496 909 Pfam PF13200 Putative glycosyl hydrolase domain 83 220 2.2E-9 T 23-10-2018 IPR025275 Putative glycosyl hydrolase domain DUF4015 A3L04_05190 c68f5e8369baa5abb9101456c1304496 909 SUPERFAMILY SSF52317 511 763 9.65E-21 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L04_05190 c68f5e8369baa5abb9101456c1304496 909 SUPERFAMILY SSF51445 85 258 4.65E-9 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L04_02925 bec135a9ab7b7b84e38d40bb3f959c7d 634 SUPERFAMILY SSF53850 27 542 2.04E-104 T 23-10-2018 A3L04_02925 bec135a9ab7b7b84e38d40bb3f959c7d 634 Gene3D G3DSA:3.90.76.10 40 189 1.8E-154 T 23-10-2018 A3L04_02925 bec135a9ab7b7b84e38d40bb3f959c7d 634 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 613 632 4.2E-7 T 23-10-2018 IPR027552 CGP-CTERM domain A3L04_02925 bec135a9ab7b7b84e38d40bb3f959c7d 634 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 72 454 1.5E-70 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain A3L04_02925 bec135a9ab7b7b84e38d40bb3f959c7d 634 Gene3D G3DSA:3.40.190.10 29 540 1.8E-154 T 23-10-2018 A3L04_02925 bec135a9ab7b7b84e38d40bb3f959c7d 634 Gene3D G3DSA:3.10.105.10 279 516 1.8E-154 T 23-10-2018 A3L04_04420 4c4313c5030c8feaa87072e1c43d04de 254 Gene3D G3DSA:3.40.1160.10 1 253 9.3E-60 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L04_04420 4c4313c5030c8feaa87072e1c43d04de 254 SUPERFAMILY SSF53633 1 254 3.27E-36 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L04_04420 4c4313c5030c8feaa87072e1c43d04de 254 Pfam PF00696 Amino acid kinase family 2 228 1.0E-41 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A3L04_04420 4c4313c5030c8feaa87072e1c43d04de 254 PIRSF PIRSF016496 1 254 8.9E-80 T 23-10-2018 IPR024192 Fosfomycin resistance kinase, FomA-type GO:0016301 KEGG: 00900+2.7.4.26|MetaCyc: PWY-6174|MetaCyc: PWY-7524 A3L04_03430 619a8adc80dda7041c03ec2e81ca60ad 141 SUPERFAMILY SSF50193 16 141 8.24E-46 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 A3L04_03430 619a8adc80dda7041c03ec2e81ca60ad 141 ProSitePatterns PS00049 Ribosomal protein L14 signature. 80 106 - T 23-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03430 619a8adc80dda7041c03ec2e81ca60ad 141 Gene3D G3DSA:2.40.150.20 3 141 2.0E-51 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 A3L04_03430 619a8adc80dda7041c03ec2e81ca60ad 141 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 20 141 20.3 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A3L04_03430 619a8adc80dda7041c03ec2e81ca60ad 141 Pfam PF00238 Ribosomal protein L14p/L23e 24 140 1.2E-36 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A3L04_03430 619a8adc80dda7041c03ec2e81ca60ad 141 TIGRFAM TIGR03673 uL14_arch: 50S ribosomal protein uL14 15 141 4.8E-63 T 23-10-2018 IPR019971 Ribosomal protein L14P, archaeal A3L04_03430 619a8adc80dda7041c03ec2e81ca60ad 141 SMART SM01374 20 141 1.0E-59 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A3L04_10825 9f1af15695aab85a8b008beb13915354 324 Pfam PF01380 SIS domain 190 245 1.1E-6 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A3L04_10825 9f1af15695aab85a8b008beb13915354 324 Pfam PF01380 SIS domain 33 151 4.8E-10 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A3L04_10825 9f1af15695aab85a8b008beb13915354 324 SUPERFAMILY SSF53697 2 323 5.1E-62 T 23-10-2018 A3L04_10825 9f1af15695aab85a8b008beb13915354 324 Gene3D G3DSA:3.40.50.10490 162 310 2.1E-45 T 23-10-2018 A3L04_10825 9f1af15695aab85a8b008beb13915354 324 Gene3D G3DSA:3.40.50.10490 2 160 1.6E-40 T 23-10-2018 A3L04_06090 943516c95aa58f8c8e298c5cfb7a3777 254 Pfam PF13353 4Fe-4S single cluster domain 30 146 4.9E-9 T 23-10-2018 A3L04_06090 943516c95aa58f8c8e298c5cfb7a3777 254 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 4 254 37.417 T 23-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 A3L04_06090 943516c95aa58f8c8e298c5cfb7a3777 254 PIRSF PIRSF000370 2 254 5.0E-32 T 23-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 A3L04_06090 943516c95aa58f8c8e298c5cfb7a3777 254 Gene3D G3DSA:3.20.20.70 4 254 3.0E-26 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_06090 943516c95aa58f8c8e298c5cfb7a3777 254 Pfam PF04055 Radical SAM superfamily 32 196 5.9E-14 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_06090 943516c95aa58f8c8e298c5cfb7a3777 254 SUPERFAMILY SSF102114 32 208 3.53E-14 T 23-10-2018 A3L04_09100 a2c5cea14ef39d338245a6c2ef304519 179 Gene3D G3DSA:3.40.50.300 1 179 1.1E-60 T 23-10-2018 A3L04_09100 a2c5cea14ef39d338245a6c2ef304519 179 Hamap MF_00039 Putative adenylate kinase. 1 160 26.274 T 23-10-2018 IPR020618 Adenylate kinase isoenzyme 6 GO:0004017|GO:0005524 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L04_09100 a2c5cea14ef39d338245a6c2ef304519 179 SUPERFAMILY SSF52540 1 153 2.25E-25 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09100 a2c5cea14ef39d338245a6c2ef304519 179 Pfam PF13238 AAA domain 3 116 3.9E-21 T 23-10-2018 A3L04_02415 11f6f15ba136512aea2b5039f9a6ccc7 121 Gene3D G3DSA:1.10.10.10 28 118 1.4E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_02415 11f6f15ba136512aea2b5039f9a6ccc7 121 ProDom PD003808 ATP-BINDING NUCLEOTIDE-BINDING PLASMID MJ0801 MJ0147 PYRAB06260 MJ0632 PYRAB09480 MJ0819 MJ1076 38 114 1.0E-7 T 23-10-2018 A3L04_08705 244891ff0b2ad84366cde18b2c29a814 84 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 4 84 4.9E-26 T 23-10-2018 IPR010038 MoaD, archaeal-type A3L04_08705 244891ff0b2ad84366cde18b2c29a814 84 SUPERFAMILY SSF54285 3 84 3.05E-21 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L04_08705 244891ff0b2ad84366cde18b2c29a814 84 Pfam PF02597 ThiS family 6 84 2.3E-21 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L04_08705 244891ff0b2ad84366cde18b2c29a814 84 Gene3D G3DSA:3.10.20.30 1 84 2.6E-25 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L04_06480 a421390da221690a781e80aa0024baaf 128 SUPERFAMILY SSF54637 13 118 2.72E-27 T 23-10-2018 IPR029069 HotDog domain superfamily A3L04_06480 a421390da221690a781e80aa0024baaf 128 Pfam PF03061 Thioesterase superfamily 41 111 1.0E-8 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A3L04_06480 a421390da221690a781e80aa0024baaf 128 Gene3D G3DSA:3.10.129.10 1 128 3.0E-45 T 23-10-2018 A3L04_08455 1cd46ce7ac64cc405a6f12280b44f5b3 256 SUPERFAMILY SSF56349 4 147 5.0E-5 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A3L04_02840 554b4ad498edcea9788614af347c6752 279 SMART SM00138 4 270 1.2E-84 T 23-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A3L04_02840 554b4ad498edcea9788614af347c6752 279 SUPERFAMILY SSF47757 3 65 5.36E-15 T 23-10-2018 A3L04_02840 554b4ad498edcea9788614af347c6752 279 Gene3D G3DSA:1.10.155.10 1 69 2.0E-9 T 23-10-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily A3L04_02840 554b4ad498edcea9788614af347c6752 279 Pfam PF03705 CheR methyltransferase, all-alpha domain 6 57 8.2E-15 T 23-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal A3L04_02840 554b4ad498edcea9788614af347c6752 279 PIRSF PIRSF000410 1 273 1.3E-77 T 23-10-2018 IPR026024 Chemotaxis protein methyltransferase CheR A3L04_02840 554b4ad498edcea9788614af347c6752 279 PRINTS PR00996 Glutamate methyltransferase family signature 209 223 6.8E-39 T 23-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A3L04_02840 554b4ad498edcea9788614af347c6752 279 PRINTS PR00996 Glutamate methyltransferase family signature 26 39 6.8E-39 T 23-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A3L04_02840 554b4ad498edcea9788614af347c6752 279 PRINTS PR00996 Glutamate methyltransferase family signature 228 251 6.8E-39 T 23-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A3L04_02840 554b4ad498edcea9788614af347c6752 279 PRINTS PR00996 Glutamate methyltransferase family signature 141 157 6.8E-39 T 23-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A3L04_02840 554b4ad498edcea9788614af347c6752 279 PRINTS PR00996 Glutamate methyltransferase family signature 105 125 6.8E-39 T 23-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A3L04_02840 554b4ad498edcea9788614af347c6752 279 PRINTS PR00996 Glutamate methyltransferase family signature 63 75 6.8E-39 T 23-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A3L04_02840 554b4ad498edcea9788614af347c6752 279 Gene3D G3DSA:3.40.50.150 70 272 3.9E-64 T 23-10-2018 A3L04_02840 554b4ad498edcea9788614af347c6752 279 Pfam PF01739 CheR methyltransferase, SAM binding domain 70 259 1.2E-57 T 23-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal A3L04_02840 554b4ad498edcea9788614af347c6752 279 SUPERFAMILY SSF53335 70 254 6.41E-48 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_08060 3925a57ce02ff3961a94c3950d185d82 79 Pfam PF13244 Domain of unknown function (DUF4040) 11 74 6.5E-11 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A3L04_00355 bb25dfd8290ae386158a37b02484712c 502 Gene3D G3DSA:3.40.640.10 86 315 8.8E-61 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L04_00355 bb25dfd8290ae386158a37b02484712c 502 Gene3D G3DSA:3.90.1150.10 340 475 3.4E-45 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L04_00355 bb25dfd8290ae386158a37b02484712c 502 Pfam PF02347 Glycine cleavage system P-protein 33 307 4.0E-11 T 23-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A3L04_00355 bb25dfd8290ae386158a37b02484712c 502 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 10 490 61.623 T 23-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 A3L04_00355 bb25dfd8290ae386158a37b02484712c 502 SUPERFAMILY SSF53383 12 488 1.13E-119 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L04_00745 e6d6b63e8c26beed955947b19982ef50 80 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 4 47 3.6E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L04_00745 e6d6b63e8c26beed955947b19982ef50 80 Gene3D G3DSA:2.10.260.10 2 42 4.9E-14 T 23-10-2018 A3L04_00745 e6d6b63e8c26beed955947b19982ef50 80 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 44 1.0E-17 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L04_00745 e6d6b63e8c26beed955947b19982ef50 80 SUPERFAMILY SSF89447 1 46 2.96E-14 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L04_00745 e6d6b63e8c26beed955947b19982ef50 80 SMART SM00966 4 49 1.6E-14 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L04_02705 564bcdaf05f9f7aa7df1e8e875cc9722 727 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 26 470 7.4E-13 T 23-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 A3L04_10645 ceb8b47d2995f56dbe403cf2bf88d6c9 113 SUPERFAMILY SSF51182 26 111 2.1E-24 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L04_10645 ceb8b47d2995f56dbe403cf2bf88d6c9 113 Gene3D G3DSA:2.60.120.10 12 111 1.4E-22 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L04_10645 ceb8b47d2995f56dbe403cf2bf88d6c9 113 Pfam PF07883 Cupin domain 32 100 4.8E-19 T 23-10-2018 IPR013096 Cupin 2, conserved barrel A3L04_05750 6d93daf58d738c4d60887b6cd2380bed 92 Gene3D G3DSA:3.30.300.130 1 86 7.8E-7 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L04_05750 6d93daf58d738c4d60887b6cd2380bed 92 Pfam PF01883 Iron-sulfur cluster assembly protein 2 61 7.8E-6 T 23-10-2018 IPR002744 MIP18 family-like A3L04_05750 6d93daf58d738c4d60887b6cd2380bed 92 SUPERFAMILY SSF117916 2 80 8.5E-9 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L04_05265 a0d61eff927e9393f91f644d1c7b4ecb 475 Gene3D G3DSA:3.50.50.60 263 404 1.3E-48 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_05265 a0d61eff927e9393f91f644d1c7b4ecb 475 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 19 137 2.7E-38 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A3L04_05265 a0d61eff927e9393f91f644d1c7b4ecb 475 SUPERFAMILY SSF46548 6 165 7.32E-33 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L04_05265 a0d61eff927e9393f91f644d1c7b4ecb 475 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 15 469 7.8E-227 T 23-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 A3L04_05265 a0d61eff927e9393f91f644d1c7b4ecb 475 Gene3D G3DSA:1.10.1060.10 4 148 1.2E-40 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L04_05265 a0d61eff927e9393f91f644d1c7b4ecb 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 397 411 1.4E-16 T 23-10-2018 A3L04_05265 a0d61eff927e9393f91f644d1c7b4ecb 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 438 445 1.4E-16 T 23-10-2018 A3L04_05265 a0d61eff927e9393f91f644d1c7b4ecb 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 178 1.4E-16 T 23-10-2018 A3L04_05265 a0d61eff927e9393f91f644d1c7b4ecb 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 295 320 1.4E-16 T 23-10-2018 A3L04_05265 a0d61eff927e9393f91f644d1c7b4ecb 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 258 3.6E-25 T 23-10-2018 A3L04_05265 a0d61eff927e9393f91f644d1c7b4ecb 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 396 412 3.6E-25 T 23-10-2018 A3L04_05265 a0d61eff927e9393f91f644d1c7b4ecb 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 295 313 3.6E-25 T 23-10-2018 A3L04_05265 a0d61eff927e9393f91f644d1c7b4ecb 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 176 3.6E-25 T 23-10-2018 A3L04_05265 a0d61eff927e9393f91f644d1c7b4ecb 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 423 445 3.6E-25 T 23-10-2018 A3L04_05265 a0d61eff927e9393f91f644d1c7b4ecb 475 Gene3D G3DSA:3.40.50.720 152 262 1.8E-25 T 23-10-2018 A3L04_05265 a0d61eff927e9393f91f644d1c7b4ecb 475 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 156 454 1.5E-42 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L04_05265 a0d61eff927e9393f91f644d1c7b4ecb 475 SUPERFAMILY SSF51971 156 404 6.47E-73 T 23-10-2018 A3L04_04555 4597efb43ba5162aa785e91efcf7547a 215 Gene3D G3DSA:3.90.550.10 3 213 5.8E-61 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_04555 4597efb43ba5162aa785e91efcf7547a 215 Pfam PF00535 Glycosyl transferase family 2 8 134 4.5E-36 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L04_04555 4597efb43ba5162aa785e91efcf7547a 215 SUPERFAMILY SSF53448 6 200 4.28E-48 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_09375 611893c8c9d590a1f77ed23961a365ea 369 PIRSF PIRSF018978 1 369 2.0E-192 T 23-10-2018 IPR016742 tRNA methyltransferase, archaea GO:0008175|GO:0030488 A3L04_09375 611893c8c9d590a1f77ed23961a365ea 369 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 127 211 9.9E-7 T 23-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 A3L04_09375 611893c8c9d590a1f77ed23961a365ea 369 Gene3D G3DSA:3.40.1280.30 93 274 1.5E-14 T 23-10-2018 IPR038459 tRNA methyltransferase TRM10-type domain superfamily A3L04_08035 4edd42cb19ab168e8ed5501bb87217b8 177 Pfam PF12838 4Fe-4S dicluster domain 43 92 3.9E-13 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L04_08035 4edd42cb19ab168e8ed5501bb87217b8 177 Gene3D G3DSA:3.30.70.3270 21 153 3.3E-20 T 23-10-2018 A3L04_08035 4edd42cb19ab168e8ed5501bb87217b8 177 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 43 54 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_08035 4edd42cb19ab168e8ed5501bb87217b8 177 SUPERFAMILY SSF54862 21 100 1.2E-22 T 23-10-2018 A3L04_08035 4edd42cb19ab168e8ed5501bb87217b8 177 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 78 89 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L04_01505 3e3ae5e4da842463657470cbe2cc5ca7 335 SUPERFAMILY SSF53335 84 332 2.69E-49 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_01505 3e3ae5e4da842463657470cbe2cc5ca7 335 Pfam PF02475 Met-10+ like-protein 87 263 3.0E-40 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A3L04_01505 3e3ae5e4da842463657470cbe2cc5ca7 335 Gene3D G3DSA:3.30.300.110 61 142 9.2E-12 T 23-10-2018 A3L04_01505 3e3ae5e4da842463657470cbe2cc5ca7 335 Gene3D G3DSA:3.40.50.150 146 334 6.2E-36 T 23-10-2018 A3L04_07550 5614071383615b101767ef563dafb1dc 636 Gene3D G3DSA:3.30.230.10 33 236 5.0E-31 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L04_07550 5614071383615b101767ef563dafb1dc 636 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 162 180 6.2E-10 T 23-10-2018 A3L04_07550 5614071383615b101767ef563dafb1dc 636 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 139 158 6.2E-10 T 23-10-2018 A3L04_07550 5614071383615b101767ef563dafb1dc 636 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 109 128 6.2E-10 T 23-10-2018 A3L04_07550 5614071383615b101767ef563dafb1dc 636 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 59 179 2.1E-15 T 23-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A3L04_07550 5614071383615b101767ef563dafb1dc 636 SUPERFAMILY SSF54211 38 232 4.17E-29 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L04_00905 4df8f79691a8d2a26f81e99b6f34549e 202 Pfam PF01936 NYN domain 27 158 4.6E-18 T 23-10-2018 IPR021139 NYN domain, limkain-b1-type A3L04_00905 4df8f79691a8d2a26f81e99b6f34549e 202 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 13 160 1.9E-59 T 23-10-2018 IPR002790 Conserved hypothetical protein CHP00288 A3L04_00905 4df8f79691a8d2a26f81e99b6f34549e 202 Gene3D G3DSA:3.40.50.1010 19 160 7.5E-9 T 23-10-2018 A3L04_00905 4df8f79691a8d2a26f81e99b6f34549e 202 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 28 100 1.0E-32 T 23-10-2018 A3L04_01765 bf15c5e4d587dd765ffb515cf0e398ff 490 SUPERFAMILY SSF69322 110 439 4.05E-5 T 23-10-2018 A3L04_01765 bf15c5e4d587dd765ffb515cf0e398ff 490 PIRSF PIRSF016666 2 490 1.1E-265 T 23-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 A3L04_01765 bf15c5e4d587dd765ffb515cf0e398ff 490 Pfam PF09910 Uncharacterized protein conserved in archaea (DUF2139) 32 365 6.6E-156 T 23-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 A3L04_08055 11a34ece356af80c05ce27d45458f423 114 Pfam PF03334 Na+/H+ antiporter subunit 10 96 3.3E-15 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L04_08055 11a34ece356af80c05ce27d45458f423 114 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 10 102 3.0E-23 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L04_07315 faf4bce95d94593bbfc62ebf70ec7afd 357 Gene3D G3DSA:3.40.50.300 162 357 3.0E-59 T 23-10-2018 A3L04_07315 faf4bce95d94593bbfc62ebf70ec7afd 357 Gene3D G3DSA:1.20.120.1190 1 161 2.3E-57 T 23-10-2018 A3L04_07315 faf4bce95d94593bbfc62ebf70ec7afd 357 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 191 209 2.3E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_07315 faf4bce95d94593bbfc62ebf70ec7afd 357 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 170 190 2.3E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_07315 faf4bce95d94593bbfc62ebf70ec7afd 357 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 218 233 2.3E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L04_07315 faf4bce95d94593bbfc62ebf70ec7afd 357 Pfam PF06858 Nucleolar GTP-binding protein 1 (NOG1) 234 291 4.4E-24 T 23-10-2018 IPR010674 Nucleolar GTP-binding protein 1, Rossman-fold domain GO:0005525 A3L04_07315 faf4bce95d94593bbfc62ebf70ec7afd 357 SUPERFAMILY SSF52540 168 342 3.27E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_07315 faf4bce95d94593bbfc62ebf70ec7afd 357 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 169 330 6.6E-17 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L04_07135 ffdc558c818fa30b24784228372648ed 329 SUPERFAMILY SSF50331 236 307 7.14E-5 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L04_07135 ffdc558c818fa30b24784228372648ed 329 Gene3D G3DSA:3.40.50.300 1 236 9.3E-77 T 23-10-2018 A3L04_07135 ffdc558c818fa30b24784228372648ed 329 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_07135 ffdc558c818fa30b24784228372648ed 329 SMART SM00382 26 209 1.5E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_07135 ffdc558c818fa30b24784228372648ed 329 SUPERFAMILY SSF52540 4 239 1.95E-90 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_07135 ffdc558c818fa30b24784228372648ed 329 Pfam PF00005 ABC transporter 20 159 4.7E-37 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_01600 ea46f035b55b2fd12fdd61813bd8ef14 304 Gene3D G3DSA:3.20.20.70 76 303 7.5E-12 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_01600 ea46f035b55b2fd12fdd61813bd8ef14 304 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 218 298 5.2E-10 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A3L04_01600 ea46f035b55b2fd12fdd61813bd8ef14 304 SUPERFAMILY SSF102114 99 282 2.31E-11 T 23-10-2018 A3L04_01600 ea46f035b55b2fd12fdd61813bd8ef14 304 Pfam PF13186 Iron-sulfur cluster-binding domain 220 276 1.1E-7 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A3L04_00165 b8710c6da7e9e64cad46384a7541d8de 204 Pfam PF02676 Methyltransferase TYW3 4 184 9.4E-39 T 23-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L04_00165 b8710c6da7e9e64cad46384a7541d8de 204 Gene3D G3DSA:3.30.1960.10 1 192 6.7E-50 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L04_00165 b8710c6da7e9e64cad46384a7541d8de 204 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 1 186 26.694 T 23-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 A3L04_00165 b8710c6da7e9e64cad46384a7541d8de 204 SUPERFAMILY SSF111278 2 183 1.31E-50 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L04_08690 5699441404f3040ee899315b4585d250 243 Hamap MF_00617 Mannosyl-3-phosphoglycerate phosphatase [mngB]. 1 243 40.697 T 23-10-2018 IPR012815 Mannosyl-3-phosphoglycerate phosphatase GO:0005737|GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 A3L04_08690 5699441404f3040ee899315b4585d250 243 SUPERFAMILY SSF56784 1 229 3.48E-40 T 23-10-2018 IPR036412 HAD-like superfamily A3L04_08690 5699441404f3040ee899315b4585d250 243 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 219 5.1E-15 T 23-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A3L04_08690 5699441404f3040ee899315b4585d250 243 Gene3D G3DSA:3.30.980.20 94 176 4.4E-73 T 23-10-2018 A3L04_08690 5699441404f3040ee899315b4585d250 243 Gene3D G3DSA:3.40.50.1000 4 216 4.4E-73 T 23-10-2018 IPR023214 HAD superfamily A3L04_08690 5699441404f3040ee899315b4585d250 243 TIGRFAM TIGR02461 osmo_MPG_phos: mannosyl-3-phosphoglycerate phosphatase 4 222 1.3E-94 T 23-10-2018 IPR033980 Mannosyl-3-phosphoglycerate phosphatase, thermophiles GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 A3L04_08690 5699441404f3040ee899315b4585d250 243 Pfam PF08282 haloacid dehalogenase-like hydrolase 136 227 7.1E-5 T 23-10-2018 A3L04_08690 5699441404f3040ee899315b4585d250 243 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 73 1.8E-7 T 23-10-2018 A3L04_08690 5699441404f3040ee899315b4585d250 243 TIGRFAM TIGR01486 HAD-SF-IIB-MPGP: mannosyl-3-phosphoglycerate phosphatase family 4 228 6.1E-75 T 23-10-2018 IPR006381 HAD-superfamily hydrolase, superfamily IIB, MPGP GO:0005737|GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 A3L04_01055 fb645890be03e269e50fe8bdc0989f54 85 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 70 1.6E-18 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 A3L04_01055 fb645890be03e269e50fe8bdc0989f54 85 SUPERFAMILY SSF143430 1 75 5.62E-24 T 23-10-2018 A3L04_01055 fb645890be03e269e50fe8bdc0989f54 85 Pfam PF09827 CRISPR associated protein Cas2 1 69 3.6E-21 T 23-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 A3L04_01055 fb645890be03e269e50fe8bdc0989f54 85 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 85 15.522 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 A3L04_01055 fb645890be03e269e50fe8bdc0989f54 85 Gene3D G3DSA:3.30.70.240 1 64 9.2E-28 T 23-10-2018 A3L04_10690 c3d8a70f39b2b9fb31c7d35fcb9705ce 328 Pfam PF01368 DHH family 20 160 8.5E-13 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A3L04_10690 c3d8a70f39b2b9fb31c7d35fcb9705ce 328 Gene3D G3DSA:3.10.310.40 221 323 4.1E-5 T 23-10-2018 A3L04_10690 c3d8a70f39b2b9fb31c7d35fcb9705ce 328 SUPERFAMILY SSF64182 18 323 3.14E-49 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L04_10690 c3d8a70f39b2b9fb31c7d35fcb9705ce 328 Gene3D G3DSA:3.90.1640.10 5 200 1.4E-35 T 23-10-2018 A3L04_10690 c3d8a70f39b2b9fb31c7d35fcb9705ce 328 Pfam PF02272 DHHA1 domain 205 318 5.8E-12 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L04_09230 c8c1ebd6d8da927a6c701074ac853c3e 140 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 36 121 8.0E-5 T 23-10-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 A3L04_09230 c8c1ebd6d8da927a6c701074ac853c3e 140 Gene3D G3DSA:1.20.120.1630 1 140 7.9E-25 T 23-10-2018 A3L04_08640 942ad0448215f1f4eb3e89617d17607a 215 SUPERFAMILY SSF81301 27 101 5.79E-8 T 23-10-2018 A3L04_08640 942ad0448215f1f4eb3e89617d17607a 215 Gene3D G3DSA:3.30.460.10 16 124 3.6E-6 T 23-10-2018 A3L04_04255 b22d570cd396b016af97399f5cf170ef 349 Pfam PF01497 Periplasmic binding protein 88 307 3.9E-41 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain A3L04_04255 b22d570cd396b016af97399f5cf170ef 349 SUPERFAMILY SSF53807 65 332 3.38E-75 T 23-10-2018 A3L04_04255 b22d570cd396b016af97399f5cf170ef 349 Gene3D G3DSA:3.40.50.1980 203 332 1.3E-37 T 23-10-2018 A3L04_04255 b22d570cd396b016af97399f5cf170ef 349 Gene3D G3DSA:3.40.50.1980 70 200 3.7E-35 T 23-10-2018 A3L04_06785 a1c071830fe02bfc66b520e09ac1722b 455 PRINTS PR00981 Seryl-tRNA synthetase signature 372 388 2.6E-34 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L04_06785 a1c071830fe02bfc66b520e09ac1722b 455 PRINTS PR00981 Seryl-tRNA synthetase signature 285 297 2.6E-34 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L04_06785 a1c071830fe02bfc66b520e09ac1722b 455 PRINTS PR00981 Seryl-tRNA synthetase signature 354 370 2.6E-34 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L04_06785 a1c071830fe02bfc66b520e09ac1722b 455 PRINTS PR00981 Seryl-tRNA synthetase signature 297 310 2.6E-34 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L04_06785 a1c071830fe02bfc66b520e09ac1722b 455 PRINTS PR00981 Seryl-tRNA synthetase signature 337 350 2.6E-34 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L04_06785 a1c071830fe02bfc66b520e09ac1722b 455 PIRSF PIRSF001529 1 447 2.7E-161 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L04_06785 a1c071830fe02bfc66b520e09ac1722b 455 SUPERFAMILY SSF46589 1 115 2.41E-27 T 23-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 A3L04_06785 a1c071830fe02bfc66b520e09ac1722b 455 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 443 42.85 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L04_06785 a1c071830fe02bfc66b520e09ac1722b 455 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 243 421 3.2E-38 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_06785 a1c071830fe02bfc66b520e09ac1722b 455 Gene3D G3DSA:1.10.287.40 1 107 8.3E-36 T 23-10-2018 A3L04_06785 a1c071830fe02bfc66b520e09ac1722b 455 Gene3D G3DSA:3.30.930.10 108 455 2.3E-143 T 23-10-2018 A3L04_06785 a1c071830fe02bfc66b520e09ac1722b 455 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 109 9.2E-28 T 23-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 A3L04_06785 a1c071830fe02bfc66b520e09ac1722b 455 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 438 1.0E-165 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L04_06785 a1c071830fe02bfc66b520e09ac1722b 455 SUPERFAMILY SSF55681 154 446 1.45E-91 T 23-10-2018 A3L04_03325 92b1fdd0d638e58b4d66ba70eeeaf786 201 SUPERFAMILY SSF52402 2 158 1.04E-42 T 23-10-2018 A3L04_03325 92b1fdd0d638e58b4d66ba70eeeaf786 201 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 2 192 8.7E-58 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 A3L04_03325 92b1fdd0d638e58b4d66ba70eeeaf786 201 Gene3D G3DSA:3.40.50.620 1 200 5.0E-58 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_04215 c0d2a1b7e1ffc51619735100db6ae382 322 Pfam PF02881 SRP54-type protein, helical bundle domain 40 99 4.1E-9 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L04_04215 c0d2a1b7e1ffc51619735100db6ae382 322 SMART SM00962 123 318 1.8E-114 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L04_04215 c0d2a1b7e1ffc51619735100db6ae382 322 Gene3D G3DSA:3.40.50.300 110 317 5.2E-85 T 23-10-2018 A3L04_04215 c0d2a1b7e1ffc51619735100db6ae382 322 Pfam PF00448 SRP54-type protein, GTPase domain 124 317 1.7E-79 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L04_04215 c0d2a1b7e1ffc51619735100db6ae382 322 SUPERFAMILY SSF52540 119 318 1.27E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_04215 c0d2a1b7e1ffc51619735100db6ae382 322 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 44 318 58.471 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A3L04_04215 c0d2a1b7e1ffc51619735100db6ae382 322 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 291 304 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L04_04215 c0d2a1b7e1ffc51619735100db6ae382 322 SUPERFAMILY SSF47364 1 107 7.59E-14 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 A3L04_04215 c0d2a1b7e1ffc51619735100db6ae382 322 SMART SM00963 20 105 1.2E-7 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L04_04215 c0d2a1b7e1ffc51619735100db6ae382 322 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 45 317 1.0E-109 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A3L04_04215 c0d2a1b7e1ffc51619735100db6ae382 322 Gene3D G3DSA:1.20.120.140 2 109 2.6E-28 T 23-10-2018 A3L04_04215 c0d2a1b7e1ffc51619735100db6ae382 322 SMART SM00382 122 298 1.0E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_03595 ae1f915d38ee01ee011db1e7d62275b5 385 SUPERFAMILY SSF103473 9 378 1.44E-19 T 23-10-2018 IPR036259 MFS transporter superfamily A3L04_03595 ae1f915d38ee01ee011db1e7d62275b5 385 Pfam PF07690 Major Facilitator Superfamily 10 337 5.0E-15 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L04_03595 ae1f915d38ee01ee011db1e7d62275b5 385 Gene3D G3DSA:1.20.1250.20 7 375 1.9E-17 T 23-10-2018 A3L04_04250 7f6b3ea64e5631845a5946558a273836 181 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 176 1.4E-35 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L04_04250 7f6b3ea64e5631845a5946558a273836 181 Gene3D G3DSA:3.40.920.10 1 181 2.3E-56 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L04_04250 7f6b3ea64e5631845a5946558a273836 181 SUPERFAMILY SSF53323 1 180 5.62E-42 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L04_07480 c002ca21d2fcd8116673e0fe994f6219 84 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 30 81 4.7E-20 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A3L04_09315 da3c516a5117f4bd6ebca4504773dd02 121 PIRSF PIRSF018867 1 118 4.6E-54 T 23-10-2018 IPR014497 Methylmalonyl-CoA decarboxylase, delta subunit A3L04_09315 da3c516a5117f4bd6ebca4504773dd02 121 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 6 80 6.3E-16 T 23-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 A3L04_09315 da3c516a5117f4bd6ebca4504773dd02 121 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 4 84 1.0E-18 T 23-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 A3L04_09390 344d138ddd9e723673b53d89f0064db6 211 Gene3D G3DSA:3.30.2010.10 100 194 9.0E-19 T 23-10-2018 A3L04_09390 344d138ddd9e723673b53d89f0064db6 211 Pfam PF01863 Protein of unknown function DUF45 88 191 2.4E-29 T 23-10-2018 IPR002725 Protein of unknown function DUF45 A3L04_09595 276f152e12ac81ae4c67cc306f9213be 931 Gene3D G3DSA:3.10.620.30 162 323 4.4E-24 T 23-10-2018 A3L04_09595 276f152e12ac81ae4c67cc306f9213be 931 SUPERFAMILY SSF54001 144 335 3.8E-34 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A3L04_09595 276f152e12ac81ae4c67cc306f9213be 931 SMART SM00460 247 315 1.1E-22 T 23-10-2018 IPR002931 Transglutaminase-like A3L04_09595 276f152e12ac81ae4c67cc306f9213be 931 Pfam PF01841 Transglutaminase-like superfamily 200 313 4.8E-29 T 23-10-2018 IPR002931 Transglutaminase-like A3L04_05640 0ba58af291a24ed90aa20869de6c4476 281 ProDom PD038341 HYDROLASE COFACTOR MOLYBDENUM BIOSYNTHESIS METAL-DEPENDENT DEOXYRIBONUCLEASE PREDICTED TATD-RELATED TVG0313409 A 114 280 5.0E-86 T 23-10-2018 A3L04_05640 0ba58af291a24ed90aa20869de6c4476 281 PIRSF PIRSF004961 1 281 2.9E-122 T 23-10-2018 IPR011589 Protein of unknown function UCP004961 A3L04_05640 0ba58af291a24ed90aa20869de6c4476 281 Pfam PF01026 TatD related DNase 5 275 5.7E-29 T 23-10-2018 IPR001130 TatD family GO:0016788 A3L04_05640 0ba58af291a24ed90aa20869de6c4476 281 Gene3D G3DSA:3.20.20.140 3 280 3.7E-25 T 23-10-2018 A3L04_05640 0ba58af291a24ed90aa20869de6c4476 281 SUPERFAMILY SSF51556 2 277 9.36E-29 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L04_04665 d2b46d6b8a0e854121862777452d3b6e 325 PIRSF PIRSF005644 1 325 1.6E-90 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A3L04_04665 d2b46d6b8a0e854121862777452d3b6e 325 Gene3D G3DSA:3.90.650.10 147 325 2.4E-45 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L04_04665 d2b46d6b8a0e854121862777452d3b6e 325 SUPERFAMILY SSF56042 148 315 1.47E-33 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L04_04665 d2b46d6b8a0e854121862777452d3b6e 325 Gene3D G3DSA:3.30.1330.10 2 141 1.1E-31 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L04_04665 d2b46d6b8a0e854121862777452d3b6e 325 SUPERFAMILY SSF55326 18 139 1.69E-27 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L04_04665 d2b46d6b8a0e854121862777452d3b6e 325 Pfam PF02769 AIR synthase related protein, C-terminal domain 149 304 9.1E-24 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L04_04665 d2b46d6b8a0e854121862777452d3b6e 325 Pfam PF00586 AIR synthase related protein, N-terminal domain 38 138 2.6E-17 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L04_08100 0e7f8ec34b93d832fe53f1f758041331 445 SUPERFAMILY SSF56821 1 429 4.88E-145 T 23-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 A3L04_08100 0e7f8ec34b93d832fe53f1f758041331 445 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 24 429 2.5E-194 T 23-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 A3L04_08100 0e7f8ec34b93d832fe53f1f758041331 445 Gene3D G3DSA:3.40.50.2030 118 260 1.4E-54 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 A3L04_08100 0e7f8ec34b93d832fe53f1f758041331 445 Gene3D G3DSA:1.20.1270.20 1 117 5.8E-30 T 23-10-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 A3L04_08100 0e7f8ec34b93d832fe53f1f758041331 445 Pfam PF03063 Prismane/CO dehydrogenase family 80 425 2.2E-96 T 23-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 A3L04_08100 0e7f8ec34b93d832fe53f1f758041331 445 Gene3D G3DSA:3.40.50.2030 261 429 5.1E-60 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 A3L04_08100 0e7f8ec34b93d832fe53f1f758041331 445 Pfam PF03063 Prismane/CO dehydrogenase family 1 83 9.7E-17 T 23-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 A3L04_08100 0e7f8ec34b93d832fe53f1f758041331 445 Hamap MF_00069 Hydroxylamine reductase [hcp]. 1 430 16.292 T 23-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 A3L04_00245 2eec3e0faecd4f5f1ed124f156a96cdf 267 Pfam PF01889 Membrane protein of unknown function DUF63 3 266 2.5E-89 T 23-10-2018 IPR002749 Protein of unknown function DUF63 A3L04_09740 b926bddf54e1e36658629b0a8a504686 162 Pfam PF05916 GINS complex protein 27 146 3.3E-8 T 23-10-2018 IPR021151 GINS subunit, domain A Reactome: R-HSA-176974 A3L04_09740 b926bddf54e1e36658629b0a8a504686 162 Gene3D G3DSA:1.20.58.2050 1 162 1.7E-73 T 23-10-2018 IPR038437 GINS complex, subunit Psf3 superfamily Reactome: R-HSA-176974 A3L04_04035 f28f0f11078ff170b4e6df924a17ec4e 203 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 194 5.4E-60 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A3L04_04035 f28f0f11078ff170b4e6df924a17ec4e 203 ProSitePatterns PS01331 Thymidylate kinase signature. 96 108 - T 23-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A3L04_04035 f28f0f11078ff170b4e6df924a17ec4e 203 Hamap MF_00165 Thymidylate kinase [tmk]. 4 202 28.81 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A3L04_04035 f28f0f11078ff170b4e6df924a17ec4e 203 Gene3D G3DSA:3.40.50.300 1 202 8.6E-71 T 23-10-2018 A3L04_04035 f28f0f11078ff170b4e6df924a17ec4e 203 Pfam PF02223 Thymidylate kinase 8 194 8.9E-57 T 23-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A3L04_04035 f28f0f11078ff170b4e6df924a17ec4e 203 SUPERFAMILY SSF52540 1 199 3.19E-54 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_04760 a557b2e617de21a0b6288b052ef0ff0a 261 Gene3D G3DSA:2.40.50.100 1 57 1.8E-22 T 23-10-2018 A3L04_04760 a557b2e617de21a0b6288b052ef0ff0a 261 SMART SM00322 146 211 9.9E-6 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L04_04760 a557b2e617de21a0b6288b052ef0ff0a 261 SMART SM00316 63 137 1.6E-9 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L04_04760 a557b2e617de21a0b6288b052ef0ff0a 261 Hamap MF_00623 Exosome complex component Rrp4 [rrp4]. 7 232 39.861 T 23-10-2018 IPR023474 Exosome complex component Rrp4 GO:0000178|GO:0008143 A3L04_04760 a557b2e617de21a0b6288b052ef0ff0a 261 SUPERFAMILY SSF50249 59 180 1.31E-18 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_04760 a557b2e617de21a0b6288b052ef0ff0a 261 Gene3D G3DSA:2.40.50.140 58 141 1.8E-22 T 23-10-2018 A3L04_04760 a557b2e617de21a0b6288b052ef0ff0a 261 Gene3D G3DSA:3.30.1370.10 149 254 4.8E-33 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L04_04760 a557b2e617de21a0b6288b052ef0ff0a 261 Pfam PF15985 KH domain 149 195 2.7E-8 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A3L04_04760 a557b2e617de21a0b6288b052ef0ff0a 261 SUPERFAMILY SSF110324 3 58 7.33E-14 T 23-10-2018 A3L04_04760 a557b2e617de21a0b6288b052ef0ff0a 261 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 11 46 1.8E-6 T 23-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L04_01465 8e1c16618cea64fbfb379d5dc80daaf2 663 Pfam PF00149 Calcineurin-like phosphoesterase 401 608 2.5E-11 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L04_01465 8e1c16618cea64fbfb379d5dc80daaf2 663 SUPERFAMILY SSF56300 400 628 1.68E-19 T 23-10-2018 A3L04_01465 8e1c16618cea64fbfb379d5dc80daaf2 663 PIRSF PIRSF000803 30 663 9.5E-202 T 23-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L04_01465 8e1c16618cea64fbfb379d5dc80daaf2 663 Gene3D G3DSA:2.40.50.430 277 383 3.8E-23 T 23-10-2018 A3L04_01465 8e1c16618cea64fbfb379d5dc80daaf2 663 Hamap MF_00325 DNA polymerase II small subunit [polB]. 3 657 32.528 T 23-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L04_01465 8e1c16618cea64fbfb379d5dc80daaf2 663 Gene3D G3DSA:1.10.8.800 1 70 6.4E-34 T 23-10-2018 A3L04_01465 8e1c16618cea64fbfb379d5dc80daaf2 663 Gene3D G3DSA:3.60.21.50 272 615 3.8E-23 T 23-10-2018 A3L04_05455 aa6e77a475d5ea0c971314c728df889e 277 Gene3D G3DSA:2.60.200.30 121 253 3.1E-65 T 23-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A3L04_05455 aa6e77a475d5ea0c971314c728df889e 277 Gene3D G3DSA:3.40.50.10330 20 266 3.1E-65 T 23-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A3L04_05455 aa6e77a475d5ea0c971314c728df889e 277 Hamap MF_00361 NAD kinase [nadK]. 1 275 29.449 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A3L04_05455 aa6e77a475d5ea0c971314c728df889e 277 Pfam PF01513 ATP-NAD kinase 2 260 3.5E-72 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A3L04_05455 aa6e77a475d5ea0c971314c728df889e 277 SUPERFAMILY SSF111331 2 264 3.53E-69 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A3L04_05195 f6f058ec997a52bdb070eaf270e8e852 424 Pfam PF04734 Neutral/alkaline non-lysosomal ceramidase, N-terminal 6 214 2.6E-13 T 23-10-2018 IPR031329 Neutral/alkaline non-lysosomal ceramidase, N-terminal KEGG: 00600+3.5.1.23|MetaCyc: PWY-6483|MetaCyc: PWY-7119|Reactome: R-HSA-1660662 A3L04_02620 265d508091df5d4b1cfd7599ade32703 413 SUPERFAMILY SSF53756 4 412 2.2E-72 T 23-10-2018 A3L04_02620 265d508091df5d4b1cfd7599ade32703 413 Pfam PF00534 Glycosyl transferases group 1 237 390 6.2E-26 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L04_02620 265d508091df5d4b1cfd7599ade32703 413 Gene3D G3DSA:3.40.50.2000 238 392 1.3E-37 T 23-10-2018 A3L04_02620 265d508091df5d4b1cfd7599ade32703 413 Pfam PF13439 Glycosyltransferase Family 4 17 226 1.5E-21 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L04_10290 249f77ee149599a75e02718b1aecddd3 95 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 23 88 4.5E-5 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L04_02525 e9361afc67686e7c492200095dbe4fe2 91 SUPERFAMILY SSF54975 2 90 1.05E-31 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L04_02525 e9361afc67686e7c492200095dbe4fe2 91 ProSitePatterns PS00150 Acylphosphatase signature 1. 10 20 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L04_02525 e9361afc67686e7c492200095dbe4fe2 91 Pfam PF00708 Acylphosphatase 7 89 4.7E-29 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L04_02525 e9361afc67686e7c492200095dbe4fe2 91 ProSitePatterns PS00151 Acylphosphatase signature 2. 34 50 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L04_02525 e9361afc67686e7c492200095dbe4fe2 91 PRINTS PR00112 Acylphosphatase signature 5 20 6.9E-9 T 23-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L04_02525 e9361afc67686e7c492200095dbe4fe2 91 PRINTS PR00112 Acylphosphatase signature 26 51 6.9E-9 T 23-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L04_02525 e9361afc67686e7c492200095dbe4fe2 91 Gene3D G3DSA:3.30.70.100 1 91 8.8E-40 T 23-10-2018 A3L04_09105 1da48bf9c5b8984d6dd91f07256d6a4c 709 SUPERFAMILY SSF52980 20 129 1.07E-6 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L04_09105 1da48bf9c5b8984d6dd91f07256d6a4c 709 Pfam PF04471 Restriction endonuclease 19 124 7.1E-14 T 23-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 A3L04_05880 1305bb098da318ef5b9a6632b57367fa 394 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 19 240 5.1E-78 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L04_05880 1305bb098da318ef5b9a6632b57367fa 394 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 264 367 6.0E-34 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A3L04_05880 1305bb098da318ef5b9a6632b57367fa 394 SUPERFAMILY SSF52922 256 376 5.5E-34 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L04_05880 1305bb098da318ef5b9a6632b57367fa 394 Gene3D G3DSA:3.40.50.970 6 253 3.7E-98 T 23-10-2018 A3L04_05880 1305bb098da318ef5b9a6632b57367fa 394 SUPERFAMILY SSF52518 7 252 5.14E-69 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L04_05880 1305bb098da318ef5b9a6632b57367fa 394 Gene3D G3DSA:3.40.50.920 254 394 2.7E-43 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L04_03780 bcd49b617ce0d7aaf1a38514c40ae86b 163 Hamap MF_01032 Methanogen homoaconitase small subunit [hacB]. 3 159 36.589 T 23-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 A3L04_03780 bcd49b617ce0d7aaf1a38514c40ae86b 163 Gene3D G3DSA:3.20.19.10 1 157 1.2E-54 T 23-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 A3L04_03780 bcd49b617ce0d7aaf1a38514c40ae86b 163 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 5 157 1.9E-66 T 23-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 A3L04_03780 bcd49b617ce0d7aaf1a38514c40ae86b 163 Pfam PF00694 Aconitase C-terminal domain 22 100 1.6E-18 T 23-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 A3L04_03780 bcd49b617ce0d7aaf1a38514c40ae86b 163 SUPERFAMILY SSF52016 3 158 3.92E-47 T 23-10-2018 A3L04_04235 0ff35f8632dda0fb789300fa27c56704 170 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 9 166 1.2E-34 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L04_04235 0ff35f8632dda0fb789300fa27c56704 170 SUPERFAMILY SSF53323 2 167 2.22E-39 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L04_04235 0ff35f8632dda0fb789300fa27c56704 170 Gene3D G3DSA:3.40.920.10 1 170 4.5E-52 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L04_07500 62541f4a3d7b5f86a05371ba35d99e81 114 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 111 1.9E-31 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A3L04_01385 bfd1ee5f2d9ec8a4f4de7d483e7ba12c 354 PIRSF PIRSF005856 27 354 2.7E-136 T 23-10-2018 IPR016467 DNA recombination and repair protein, RecA-like Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 A3L04_01385 bfd1ee5f2d9ec8a4f4de7d483e7ba12c 354 Gene3D G3DSA:1.10.150.20 40 103 3.2E-24 T 23-10-2018 A3L04_01385 bfd1ee5f2d9ec8a4f4de7d483e7ba12c 354 Pfam PF08423 Rad51 102 354 2.5E-94 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 A3L04_01385 bfd1ee5f2d9ec8a4f4de7d483e7ba12c 354 Gene3D G3DSA:3.40.50.300 104 354 4.0E-86 T 23-10-2018 A3L04_01385 bfd1ee5f2d9ec8a4f4de7d483e7ba12c 354 SMART SM00278 73 92 110.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L04_01385 bfd1ee5f2d9ec8a4f4de7d483e7ba12c 354 SMART SM00278 40 59 0.081 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L04_01385 bfd1ee5f2d9ec8a4f4de7d483e7ba12c 354 Hamap MF_00348 DNA repair and recombination protein RadA [radA]. 39 354 82.237 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 A3L04_01385 bfd1ee5f2d9ec8a4f4de7d483e7ba12c 354 Pfam PF14520 Helix-hairpin-helix domain 40 95 2.3E-11 T 23-10-2018 A3L04_01385 bfd1ee5f2d9ec8a4f4de7d483e7ba12c 354 TIGRFAM TIGR02236 recomb_radA: DNA repair and recombination protein RadA 42 354 6.6E-165 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 A3L04_01385 bfd1ee5f2d9ec8a4f4de7d483e7ba12c 354 SUPERFAMILY SSF52540 115 353 1.69E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01385 bfd1ee5f2d9ec8a4f4de7d483e7ba12c 354 SUPERFAMILY SSF47794 42 100 4.55E-13 T 23-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 A3L04_01385 bfd1ee5f2d9ec8a4f4de7d483e7ba12c 354 SMART SM00382 135 324 3.9E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_07790 57ff66a44689c3fd20b3d4b3ca4d5394 277 Gene3D G3DSA:3.80.30.30 51 256 1.5E-12 T 23-10-2018 A3L04_07790 57ff66a44689c3fd20b3d4b3ca4d5394 277 Pfam PF04055 Radical SAM superfamily 23 187 4.0E-15 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_07790 57ff66a44689c3fd20b3d4b3ca4d5394 277 SUPERFAMILY SSF102114 8 210 7.19E-15 T 23-10-2018 A3L04_07790 57ff66a44689c3fd20b3d4b3ca4d5394 277 SMART SM00729 18 228 6.0E-12 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L04_04870 394b5fda2986ab45a33a35cb7f394a46 361 Gene3D G3DSA:2.40.390.10 229 338 1.7E-6 T 23-10-2018 IPR024071 Protein of unknown function DUF917, C-terminal A3L04_04870 394b5fda2986ab45a33a35cb7f394a46 361 SUPERFAMILY SSF160991 4 339 2.48E-79 T 23-10-2018 A3L04_04870 394b5fda2986ab45a33a35cb7f394a46 361 Pfam PF06032 Protein of unknown function (DUF917) 11 330 1.7E-60 T 23-10-2018 IPR010318 Protein of unknown function DUF917 A3L04_04870 394b5fda2986ab45a33a35cb7f394a46 361 Gene3D G3DSA:3.40.1610.10 2 222 3.1E-23 T 23-10-2018 IPR027479 Protein of unknown function DUF917, N-terminal A3L04_07405 088bd22505ad1a30a98a94265bbe1f09 215 SUPERFAMILY SSF56112 11 152 6.07E-13 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A3L04_07405 088bd22505ad1a30a98a94265bbe1f09 215 Gene3D G3DSA:3.30.200.20 17 98 2.7E-5 T 23-10-2018 A3L04_10540 af61b2f796309b5146a9ab7cd61cdb10 537 Gene3D G3DSA:3.40.50.300 254 489 8.9E-80 T 23-10-2018 A3L04_10540 af61b2f796309b5146a9ab7cd61cdb10 537 Gene3D G3DSA:1.10.8.1140 490 536 6.0E-11 T 23-10-2018 A3L04_10540 af61b2f796309b5146a9ab7cd61cdb10 537 Gene3D G3DSA:1.10.390.40 81 155 2.9E-58 T 23-10-2018 A3L04_10540 af61b2f796309b5146a9ab7cd61cdb10 537 SUPERFAMILY SSF52540 138 513 4.76E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_10540 af61b2f796309b5146a9ab7cd61cdb10 537 Pfam PF00437 Type II/IV secretion system protein 158 402 9.6E-50 T 23-10-2018 IPR001482 Type II/IV secretion system protein A3L04_10540 af61b2f796309b5146a9ab7cd61cdb10 537 Gene3D G3DSA:3.30.450.370 49 253 2.9E-58 T 23-10-2018 A3L04_00525 854e135fd111b1b9df6860a5c295c19b 255 TIGRFAM TIGR02495 NrdG2: anaerobic ribonucleoside-triphosphate reductase activating protein 3 192 3.2E-54 T 23-10-2018 IPR012840 Anaerobic ribonucleoside-triphosphate reductase activating protein A3L04_00525 854e135fd111b1b9df6860a5c295c19b 255 Pfam PF04055 Radical SAM superfamily 26 172 2.9E-18 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_00525 854e135fd111b1b9df6860a5c295c19b 255 SUPERFAMILY SSF102114 26 182 4.19E-20 T 23-10-2018 A3L04_00525 854e135fd111b1b9df6860a5c295c19b 255 Gene3D G3DSA:3.20.20.70 3 187 1.0E-22 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_00525 854e135fd111b1b9df6860a5c295c19b 255 Pfam PF13353 4Fe-4S single cluster domain 18 90 3.7E-9 T 23-10-2018 A3L04_09160 6fcf8368adbf34e592ab23c90def58d0 480 Gene3D G3DSA:1.20.1730.10 11 478 6.3E-59 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily A3L04_09160 6fcf8368adbf34e592ab23c90def58d0 480 Pfam PF00474 Sodium:solute symporter family 36 427 2.5E-36 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A3L04_10580 45d9af6aeb04b3e4bc6b91e3d4b8a147 210 Pfam PF01917 Archaebacterial flagellin 4 196 4.2E-47 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 A3L04_10580 45d9af6aeb04b3e4bc6b91e3d4b8a147 210 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 2 25 1.7E-5 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal A3L04_10065 4023c3de21279e978f5f71a8a58faf68 261 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 17 247 1.4E-12 T 23-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 A3L04_10065 4023c3de21279e978f5f71a8a58faf68 261 Gene3D G3DSA:3.40.830.10 1 261 4.2E-69 T 23-10-2018 A3L04_10065 4023c3de21279e978f5f71a8a58faf68 261 SUPERFAMILY SSF53213 6 259 1.44E-21 T 23-10-2018 A3L04_01415 b0b9d73d5aa17f534995fde0fb122a3c 244 Pfam PF02361 Cobalt transport protein 10 213 4.7E-30 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component A3L04_02860 9b4b1e1d6c5024a64401dc15fee48b8a 211 SUPERFAMILY SSF103039 13 206 3.23E-47 T 23-10-2018 IPR028976 CheC-like superfamily A3L04_02860 9b4b1e1d6c5024a64401dc15fee48b8a 211 Gene3D G3DSA:3.40.1550.10 12 207 3.2E-55 T 23-10-2018 IPR028976 CheC-like superfamily A3L04_02860 9b4b1e1d6c5024a64401dc15fee48b8a 211 Pfam PF04509 CheC-like family 18 52 1.9E-8 T 23-10-2018 IPR007597 CheC-like protein GO:0016787 A3L04_02860 9b4b1e1d6c5024a64401dc15fee48b8a 211 Pfam PF04509 CheC-like family 117 149 2.0E-6 T 23-10-2018 IPR007597 CheC-like protein GO:0016787 A3L04_04475 0777a83018edd21ac6d9dd4dff84b41c 419 Pfam PF04055 Radical SAM superfamily 123 287 4.6E-27 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_04475 0777a83018edd21ac6d9dd4dff84b41c 419 Gene3D G3DSA:3.20.20.70 111 354 2.6E-38 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_04475 0777a83018edd21ac6d9dd4dff84b41c 419 SUPERFAMILY SSF102114 108 339 1.19E-40 T 23-10-2018 A3L04_04475 0777a83018edd21ac6d9dd4dff84b41c 419 SMART SM00729 115 330 2.2E-14 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L04_09940 9af5ff7b0744c0d05407800dacfea1a4 395 Pfam PF07690 Major Facilitator Superfamily 15 354 2.3E-19 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L04_09940 9af5ff7b0744c0d05407800dacfea1a4 395 SUPERFAMILY SSF103473 3 390 1.96E-32 T 23-10-2018 IPR036259 MFS transporter superfamily A3L04_09940 9af5ff7b0744c0d05407800dacfea1a4 395 Gene3D G3DSA:1.20.1250.20 193 390 2.1E-7 T 23-10-2018 A3L04_09940 9af5ff7b0744c0d05407800dacfea1a4 395 Gene3D G3DSA:1.20.1250.20 2 184 1.4E-10 T 23-10-2018 A3L04_08660 ff271d588a5373faca7fce6304f2fd4a 367 Gene3D G3DSA:3.40.50.300 15 215 4.5E-33 T 23-10-2018 A3L04_08660 ff271d588a5373faca7fce6304f2fd4a 367 Pfam PF01637 ATPase domain predominantly from Archaea 30 255 1.1E-16 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_08660 ff271d588a5373faca7fce6304f2fd4a 367 Gene3D G3DSA:1.10.8.60 216 293 4.6E-20 T 23-10-2018 A3L04_08660 ff271d588a5373faca7fce6304f2fd4a 367 SUPERFAMILY SSF52540 18 288 1.0E-32 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_03730 8b4b3b4074884a4838826eb7b9505fab 220 ProDom PD019177 PF1672 MJ0935 ST1363 PH1730 UNCHARACTERIZED ARCHAEAL 4 49 3.0E-14 T 23-10-2018 IPR007368 Protein of unknown function DUF434 A3L04_03730 8b4b3b4074884a4838826eb7b9505fab 220 Pfam PF04256 Protein of unknown function (DUF434) 3 52 1.8E-20 T 23-10-2018 IPR007368 Protein of unknown function DUF434 A3L04_04980 3435d41b2dcded5e14d65ba4fbceade1 109 SMART SM01407 6 63 2.2E-17 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain A3L04_04980 3435d41b2dcded5e14d65ba4fbceade1 109 SUPERFAMILY SSF46934 67 109 8.5E-9 T 23-10-2018 IPR009060 UBA-like superfamily GO:0005515 A3L04_04980 3435d41b2dcded5e14d65ba4fbceade1 109 TIGRFAM TIGR00264 TIGR00264: alpha-NAC homolog 1 108 7.2E-36 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 A3L04_04980 3435d41b2dcded5e14d65ba4fbceade1 109 Hamap MF_00814 Nascent polypeptide-associated complex protein [nac]. 7 107 19.49 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 A3L04_04980 3435d41b2dcded5e14d65ba4fbceade1 109 Gene3D G3DSA:1.10.8.10 68 107 4.0E-21 T 23-10-2018 A3L04_04980 3435d41b2dcded5e14d65ba4fbceade1 109 Gene3D G3DSA:2.20.70.30 10 67 1.3E-20 T 23-10-2018 IPR038187 NAC A/B domain superfamily A3L04_04980 3435d41b2dcded5e14d65ba4fbceade1 109 Pfam PF01849 NAC domain 6 63 4.9E-15 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain A3L04_06210 6f3f72576d05bca6c100504d830a60ac 102 Gene3D G3DSA:3.30.460.10 1 102 1.2E-18 T 23-10-2018 A3L04_06210 6f3f72576d05bca6c100504d830a60ac 102 SUPERFAMILY SSF81301 6 91 4.09E-16 T 23-10-2018 A3L04_06210 6f3f72576d05bca6c100504d830a60ac 102 Pfam PF01909 Nucleotidyltransferase domain 6 58 5.0E-11 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L04_04295 c34745cae0b0eefc782ee6effda89ebd 513 Pfam PF09594 Glycosyltransferase family 87 229 344 1.4E-5 T 23-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 A3L04_02985 24e56a334515a9641530b5b1a9c47362 204 Gene3D G3DSA:3.40.50.11570 4 204 2.9E-14 T 23-10-2018 A3L04_02985 24e56a334515a9641530b5b1a9c47362 204 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 10 198 1.2E-13 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L04_10070 be94f71b6f8ba7d6f26b2cc3fc1c199f 377 Pfam PF05559 Protein of unknown function (DUF763) 4 332 4.7E-121 T 23-10-2018 IPR008482 Protein of unknown function DUF763 A3L04_08145 1ec4797e34f564669dc0f9206799b741 419 SUPERFAMILY SSF143968 280 416 3.14E-43 T 23-10-2018 A3L04_08145 1ec4797e34f564669dc0f9206799b741 419 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 407 1.2E-114 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 A3L04_08145 1ec4797e34f564669dc0f9206799b741 419 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 6 383 2.2E-97 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 A3L04_08145 1ec4797e34f564669dc0f9206799b741 419 SUPERFAMILY SSF50475 5 277 5.89E-63 T 23-10-2018 A3L04_08145 1ec4797e34f564669dc0f9206799b741 419 Gene3D G3DSA:3.40.1670.10 294 406 1.2E-38 T 23-10-2018 A3L04_10090 520cc90dd91865f43a895b60f237a7a1 222 SUPERFAMILY SSF159612 2 220 1.09E-109 T 23-10-2018 A3L04_10090 520cc90dd91865f43a895b60f237a7a1 222 Pfam PF15517 TBP-interacting protein N-terminus 3 102 5.4E-45 T 23-10-2018 IPR029125 TBP-interacting protein, N-terminal A3L04_10090 520cc90dd91865f43a895b60f237a7a1 222 Gene3D G3DSA:3.90.79.30 101 220 1.0E-52 T 23-10-2018 A3L04_10090 520cc90dd91865f43a895b60f237a7a1 222 Gene3D G3DSA:3.40.1350.70 1 100 6.9E-29 T 23-10-2018 IPR038230 TBP-interacting protein, N-terminal superfamily A3L04_10575 9b00bef5a7fe1945c86b9aa08448308a 220 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 2 25 7.6E-6 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal A3L04_10575 9b00bef5a7fe1945c86b9aa08448308a 220 Pfam PF01917 Archaebacterial flagellin 4 206 5.7E-45 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 A3L04_08090 f06511c59cfa66eb8a403357365c75cc 190 SUPERFAMILY SSF53448 1 185 7.21E-26 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_08090 f06511c59cfa66eb8a403357365c75cc 190 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 188 19.393 T 23-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 A3L04_08090 f06511c59cfa66eb8a403357365c75cc 190 Gene3D G3DSA:3.90.550.10 4 190 2.1E-39 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_08090 f06511c59cfa66eb8a403357365c75cc 190 Pfam PF12804 MobA-like NTP transferase domain 3 143 5.6E-25 T 23-10-2018 IPR025877 MobA-like NTP transferase A3L04_10735 90eeed31fef942f394946d2f9e92fd43 77 Gene3D G3DSA:3.10.20.10 3 76 6.5E-27 T 23-10-2018 A3L04_10735 90eeed31fef942f394946d2f9e92fd43 77 Hamap MF_00273 50S ribosomal protein L18Ae [rpl18a]. 3 58 19.031 T 23-10-2018 IPR028877 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_10735 90eeed31fef942f394946d2f9e92fd43 77 Pfam PF01775 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A 2 58 2.4E-13 T 23-10-2018 IPR023573 Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_10735 90eeed31fef942f394946d2f9e92fd43 77 SUPERFAMILY SSF160374 2 73 5.75E-25 T 23-10-2018 A3L04_10735 90eeed31fef942f394946d2f9e92fd43 77 ProDom PD010302 RIBOSOMAL LX 50S RIBONUCLEOPROTEIN HL32 DIRECT SEQUENCING LXA LSU 6 50 5.0E-16 T 23-10-2018 IPR002768 50S ribosomal protein L18Ae, archaea GO:0003735|GO:0005840|GO:0006412 A3L04_07410 6e03d2c559e033e935468f3f2588044a 383 PIRSF PIRSF000524 11 383 5.0E-99 T 23-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 A3L04_07410 6e03d2c559e033e935468f3f2588044a 383 SUPERFAMILY SSF53383 5 377 7.85E-94 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L04_07410 6e03d2c559e033e935468f3f2588044a 383 Pfam PF00266 Aminotransferase class-V 40 363 2.6E-36 T 23-10-2018 IPR000192 Aminotransferase class V domain A3L04_07410 6e03d2c559e033e935468f3f2588044a 383 Gene3D G3DSA:3.90.1150.10 19 373 1.5E-140 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L04_07410 6e03d2c559e033e935468f3f2588044a 383 Gene3D G3DSA:3.40.640.10 29 274 1.5E-140 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L04_00635 b932da50d9a50bcdef954ec83d32c476 178 SUPERFAMILY SSF53448 1 172 3.03E-19 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_00635 b932da50d9a50bcdef954ec83d32c476 178 Pfam PF12804 MobA-like NTP transferase domain 3 106 1.2E-13 T 23-10-2018 IPR025877 MobA-like NTP transferase A3L04_00635 b932da50d9a50bcdef954ec83d32c476 178 Gene3D G3DSA:3.90.550.10 2 175 8.8E-29 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_02080 726f0ad217b48ed175ce6f9d26e41783 353 Gene3D G3DSA:1.10.3720.10 115 342 3.3E-15 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_02080 726f0ad217b48ed175ce6f9d26e41783 353 SUPERFAMILY SSF161098 120 329 1.57E-12 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_02080 726f0ad217b48ed175ce6f9d26e41783 353 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 142 346 2.1E-39 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L04_04930 75504175e481ff5b660b08aa4a739409 66 SUPERFAMILY SSF47413 2 65 1.88E-21 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L04_04930 75504175e481ff5b660b08aa4a739409 66 Gene3D G3DSA:1.10.260.40 1 65 1.4E-31 T 23-10-2018 A3L04_04930 75504175e481ff5b660b08aa4a739409 66 SMART SM00530 4 59 9.7E-20 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L04_04930 75504175e481ff5b660b08aa4a739409 66 Pfam PF01381 Helix-turn-helix 5 58 6.5E-19 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L04_07570 08a173ab699b8061fff3b215e93d1706 430 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 122 381 7.3E-61 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07570 08a173ab699b8061fff3b215e93d1706 430 Pfam PF00374 Nickel-dependent hydrogenase 47 114 2.7E-14 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L04_07570 08a173ab699b8061fff3b215e93d1706 430 Gene3D G3DSA:1.10.645.20 9 381 3.1E-124 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07570 08a173ab699b8061fff3b215e93d1706 430 SUPERFAMILY SSF56762 18 381 6.02E-106 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_10660 89b5661c8c47b68ff0a11e3410583168 241 SUPERFAMILY SSF50249 134 222 2.45E-15 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_10660 89b5661c8c47b68ff0a11e3410583168 241 Gene3D G3DSA:1.20.1440.150 1 124 1.8E-62 T 23-10-2018 A3L04_10660 89b5661c8c47b68ff0a11e3410583168 241 Gene3D G3DSA:2.40.50.140 125 241 2.2E-34 T 23-10-2018 A3L04_10660 89b5661c8c47b68ff0a11e3410583168 241 Pfam PF01588 Putative tRNA binding domain 138 224 1.6E-17 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A3L04_03510 e2578a7fb180e49fa21dfc19e04bf758 375 SUPERFAMILY SSF54373 211 301 1.86E-10 T 23-10-2018 A3L04_03510 e2578a7fb180e49fa21dfc19e04bf758 375 Pfam PF01266 FAD dependent oxidoreductase 2 341 1.4E-77 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A3L04_03510 e2578a7fb180e49fa21dfc19e04bf758 375 Gene3D G3DSA:3.30.9.10 80 304 3.0E-117 T 23-10-2018 A3L04_03510 e2578a7fb180e49fa21dfc19e04bf758 375 Gene3D G3DSA:3.50.50.60 4 346 3.0E-117 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_03510 e2578a7fb180e49fa21dfc19e04bf758 375 SUPERFAMILY SSF51905 4 366 1.42E-55 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_09530 d935a6e872f11a081e5af5ff51340f3c 333 Pfam PF07760 Protein of unknown function (DUF1616) 15 327 1.2E-95 T 23-10-2018 IPR011674 Domain of unknown function DUF1616 A3L04_09530 d935a6e872f11a081e5af5ff51340f3c 333 PIRSF PIRSF018671 3 333 6.8E-128 T 23-10-2018 IPR014495 Uncharacterised conserved protein UCP018671 A3L04_09995 8183276203daac52c33b4ba1b0757b8a 82 ProDom PD486863 PRECURSOR CBIM SIGNAL COBALT MEMBRANE VITAMIN B12 BIOSYNTHESIS COBALAMIN ABC-TYPE 23 81 2.0E-4 T 23-10-2018 A3L04_07975 6417a9a92650fc10bbfb49d5944a2c89 314 Pfam PF04055 Radical SAM superfamily 25 191 5.8E-15 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_07975 6417a9a92650fc10bbfb49d5944a2c89 314 SMART SM00729 15 227 1.5E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L04_07975 6417a9a92650fc10bbfb49d5944a2c89 314 Gene3D G3DSA:3.20.20.70 20 239 3.6E-20 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_07975 6417a9a92650fc10bbfb49d5944a2c89 314 SUPERFAMILY SSF102114 25 223 7.06E-22 T 23-10-2018 A3L04_06515 bbd30b378c85f67ea35ff038b48515cf 192 Gene3D G3DSA:3.40.30.10 41 149 3.8E-11 T 23-10-2018 A3L04_06515 bbd30b378c85f67ea35ff038b48515cf 192 SUPERFAMILY SSF52833 46 148 1.48E-14 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L04_05525 531d2ad2c9fafd53672d3de012256206 125 Gene3D G3DSA:2.30.30.110 24 125 7.6E-16 T 23-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A3L04_05525 531d2ad2c9fafd53672d3de012256206 125 SUPERFAMILY SSF50118 10 125 2.01E-13 T 23-10-2018 A3L04_05525 531d2ad2c9fafd53672d3de012256206 125 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 10 122 1.1E-12 T 23-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 A3L04_03645 5e94b0fffca1ce2774030e39fb53a8db 204 Gene3D G3DSA:3.40.190.10 86 170 3.7E-64 T 23-10-2018 A3L04_03645 5e94b0fffca1ce2774030e39fb53a8db 204 SUPERFAMILY SSF53850 1 202 5.84E-63 T 23-10-2018 A3L04_03645 5e94b0fffca1ce2774030e39fb53a8db 204 Pfam PF01634 ATP phosphoribosyltransferase 46 198 1.0E-50 T 23-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A3L04_03645 5e94b0fffca1ce2774030e39fb53a8db 204 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 1 177 1.4E-60 T 23-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A3L04_03645 5e94b0fffca1ce2774030e39fb53a8db 204 Gene3D G3DSA:3.40.190.10 3 192 3.7E-64 T 23-10-2018 A3L04_03645 5e94b0fffca1ce2774030e39fb53a8db 204 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 1 202 50.479 T 23-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 A3L04_03645 5e94b0fffca1ce2774030e39fb53a8db 204 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 137 158 - T 23-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 A3L04_07495 d3aae3f0d6eaae2cf5cdeeebe634add3 235 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 98 221 9.7E-23 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A3L04_07590 966e50d1dbcbcb3e0916f5933f55b4e8 510 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 71 119 5.3E-14 T 23-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07590 966e50d1dbcbcb3e0916f5933f55b4e8 510 Pfam PF00361 Proton-conducting membrane transporter 133 433 1.8E-62 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07590 966e50d1dbcbcb3e0916f5933f55b4e8 510 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 316 328 9.0E-17 T 23-10-2018 A3L04_07590 966e50d1dbcbcb3e0916f5933f55b4e8 510 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 109 129 9.0E-17 T 23-10-2018 A3L04_07590 966e50d1dbcbcb3e0916f5933f55b4e8 510 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 81 106 9.0E-17 T 23-10-2018 A3L04_07590 966e50d1dbcbcb3e0916f5933f55b4e8 510 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 221 242 9.0E-17 T 23-10-2018 A3L04_00460 ee91d25798805759f678dbb470c4754f 205 SUPERFAMILY SSF143447 4 202 6.8E-69 T 23-10-2018 IPR036071 AMMECR1 domain superfamily A3L04_00460 ee91d25798805759f678dbb470c4754f 205 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 11 190 1.4E-58 T 23-10-2018 IPR027623 AmmeMemoRadiSam system protein A A3L04_00460 ee91d25798805759f678dbb470c4754f 205 Gene3D G3DSA:3.30.700.20 6 197 3.7E-75 T 23-10-2018 IPR027485 AMMECR1, N-terminal A3L04_00460 ee91d25798805759f678dbb470c4754f 205 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 4 197 2.6E-70 T 23-10-2018 IPR023473 AMMECR1 A3L04_00460 ee91d25798805759f678dbb470c4754f 205 Pfam PF01871 AMMECR1 13 190 1.8E-53 T 23-10-2018 IPR002733 AMMECR1 domain A3L04_00460 ee91d25798805759f678dbb470c4754f 205 Hamap MF_00645 Protein . 5 188 41.578 T 23-10-2018 IPR023472 Uncharacterised protein family MJ0810 A3L04_00460 ee91d25798805759f678dbb470c4754f 205 Gene3D G3DSA:3.30.1490.150 113 186 3.7E-75 T 23-10-2018 A3L04_05315 fad212ca3544b527a17b999970ed0fb5 208 SUPERFAMILY SSF52540 1 192 9.2E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_05315 fad212ca3544b527a17b999970ed0fb5 208 SMART SM00382 26 205 7.5E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_05315 fad212ca3544b527a17b999970ed0fb5 208 Gene3D G3DSA:3.40.50.300 1 199 6.0E-36 T 23-10-2018 A3L04_05315 fad212ca3544b527a17b999970ed0fb5 208 ProSitePatterns PS00211 ABC transporters family signature. 123 137 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_05315 fad212ca3544b527a17b999970ed0fb5 208 Pfam PF00005 ABC transporter 19 151 7.7E-22 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_00170 def80c61d6b84e9104b02695755c9ae4 329 SUPERFAMILY SSF102114 18 253 2.09E-16 T 23-10-2018 A3L04_00170 def80c61d6b84e9104b02695755c9ae4 329 SMART SM00729 16 245 1.8E-30 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L04_00170 def80c61d6b84e9104b02695755c9ae4 329 TIGRFAM TIGR01210 TIGR01210: radical SAM enzyme, TIGR01210 family 2 318 5.7E-135 T 23-10-2018 IPR005909 Conserved hypothetical protein CHP01210 A3L04_00170 def80c61d6b84e9104b02695755c9ae4 329 PIRSF PIRSF004954 1 323 7.0E-101 T 23-10-2018 IPR005909 Conserved hypothetical protein CHP01210 A3L04_00170 def80c61d6b84e9104b02695755c9ae4 329 Pfam PF04055 Radical SAM superfamily 34 180 1.3E-11 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_01745 64b7f7c1a686cb8adfb1fedcbee1432d 297 Pfam PF03168 Late embryogenesis abundant protein 187 264 1.1E-8 T 23-10-2018 IPR004864 Late embryogenesis abundant protein, LEA_2 subgroup A3L04_01745 64b7f7c1a686cb8adfb1fedcbee1432d 297 SUPERFAMILY SSF117070 28 121 2.88E-6 T 23-10-2018 A3L04_01745 64b7f7c1a686cb8adfb1fedcbee1432d 297 Gene3D G3DSA:2.60.40.10 28 147 1.9E-12 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L04_01745 64b7f7c1a686cb8adfb1fedcbee1432d 297 Gene3D G3DSA:2.60.40.10 166 295 5.8E-29 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L04_01745 64b7f7c1a686cb8adfb1fedcbee1432d 297 SMART SM00769 167 285 2.3E-21 T 23-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 A3L04_01745 64b7f7c1a686cb8adfb1fedcbee1432d 297 SMART SM00769 27 139 3.4E-10 T 23-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 A3L04_01745 64b7f7c1a686cb8adfb1fedcbee1432d 297 SUPERFAMILY SSF117070 152 257 1.19E-18 T 23-10-2018 A3L04_00430 24b7e96242d7219fb3e2db0da21871ee 274 Hamap MF_00562 D-aminoacyl-tRNA deacylase [dtdA]. 1 273 35.512 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 A3L04_00430 24b7e96242d7219fb3e2db0da21871ee 274 Gene3D G3DSA:3.40.630.50 1 186 1.4E-70 T 23-10-2018 A3L04_00430 24b7e96242d7219fb3e2db0da21871ee 274 Gene3D G3DSA:3.40.50.10700 188 274 1.4E-31 T 23-10-2018 A3L04_00430 24b7e96242d7219fb3e2db0da21871ee 274 PIRSF PIRSF016210 1 274 4.3E-86 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 A3L04_00430 24b7e96242d7219fb3e2db0da21871ee 274 Pfam PF04414 D-aminoacyl-tRNA deacylase 70 271 5.8E-65 T 23-10-2018 IPR007508 D-aminoacyl-tRNA deacylase DtdA GO:0016788|GO:0051499 A3L04_00430 24b7e96242d7219fb3e2db0da21871ee 274 SUPERFAMILY SSF142535 1 273 7.19E-89 T 23-10-2018 A3L04_08760 a1f251ea20baf42faf9d9ae190c56445 258 SUPERFAMILY SSF51366 5 249 2.83E-28 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L04_08760 a1f251ea20baf42faf9d9ae190c56445 258 ProDom PD011184 BTPA I PHOTOSYSTEM BIOGENESIS ASSEMBLY SGCQ TRIPHOSPHATASE NUCLEOSIDE PAE3553 ENZYME 27 198 3.0E-67 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A3L04_08760 a1f251ea20baf42faf9d9ae190c56445 258 PIRSF PIRSF005956 1 257 1.3E-96 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A3L04_08760 a1f251ea20baf42faf9d9ae190c56445 258 TIGRFAM TIGR00259 thylakoid_BtpA: membrane complex biogenesis protein, BtpA family 6 251 4.5E-98 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A3L04_08760 a1f251ea20baf42faf9d9ae190c56445 258 Pfam PF03437 BtpA family 5 251 4.7E-99 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A3L04_06755 0b9eb66d5ea2946513e70ec36320cb08 432 SUPERFAMILY SSF103473 36 411 4.71E-43 T 23-10-2018 IPR036259 MFS transporter superfamily A3L04_06755 0b9eb66d5ea2946513e70ec36320cb08 432 Pfam PF07690 Major Facilitator Superfamily 44 375 5.8E-27 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L04_06755 0b9eb66d5ea2946513e70ec36320cb08 432 Gene3D G3DSA:1.20.1250.20 28 411 1.7E-38 T 23-10-2018 A3L04_00540 3227dbd5f18798d9b0d151a34261210f 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 268 3.7E-21 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L04_00540 3227dbd5f18798d9b0d151a34261210f 277 Gene3D G3DSA:1.10.3720.10 2 270 3.8E-53 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_00540 3227dbd5f18798d9b0d151a34261210f 277 SUPERFAMILY SSF161098 9 269 1.5E-55 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_00810 ed5c7ef70bfbd9471faa6aa8cdb42c47 230 Gene3D G3DSA:3.40.50.720 2 230 1.3E-72 T 23-10-2018 A3L04_00810 ed5c7ef70bfbd9471faa6aa8cdb42c47 230 Pfam PF00899 ThiF family 10 229 6.8E-58 T 23-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A3L04_00810 ed5c7ef70bfbd9471faa6aa8cdb42c47 230 SUPERFAMILY SSF69572 2 227 3.4E-79 T 23-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 A3L04_10095 dda9e90952af552ccdc50088d27f6417 391 SUPERFAMILY SSF103473 1 389 1.44E-57 T 23-10-2018 IPR036259 MFS transporter superfamily A3L04_10095 dda9e90952af552ccdc50088d27f6417 391 Gene3D G3DSA:1.20.1250.20 207 391 3.6E-21 T 23-10-2018 A3L04_10095 dda9e90952af552ccdc50088d27f6417 391 Gene3D G3DSA:1.20.1250.20 10 201 1.7E-23 T 23-10-2018 A3L04_10095 dda9e90952af552ccdc50088d27f6417 391 Pfam PF07690 Major Facilitator Superfamily 17 260 2.5E-27 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L04_09270 10baa9739c98bbb0ab3db743e5648540 271 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 3 250 1.1E-35 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L04_09270 10baa9739c98bbb0ab3db743e5648540 271 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 144 260 6.2E-17 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L04_09270 10baa9739c98bbb0ab3db743e5648540 271 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 2 151 4.1E-21 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L04_07985 429a79d931a1c3f5a76130c6083b0657 73 Pfam PF14358 Domain of unknown function (DUF4405) 6 62 1.1E-6 T 23-10-2018 IPR025517 Domain of unknown function DUF4405 A3L04_03140 27978ab1e136e8a206266ec95593d30c 287 SMART SM00493 5 84 4.5E-9 T 23-10-2018 IPR006171 TOPRIM domain A3L04_03140 27978ab1e136e8a206266ec95593d30c 287 Pfam PF01751 Toprim domain 8 87 2.1E-8 T 23-10-2018 IPR006171 TOPRIM domain A3L04_03140 27978ab1e136e8a206266ec95593d30c 287 PIRSF PIRSF016662 1 287 1.3E-127 T 23-10-2018 IPR014481 Uncharacterised conserved protein UCP016662, toprim-type A3L04_03140 27978ab1e136e8a206266ec95593d30c 287 Gene3D G3DSA:3.40.1360.10 4 126 5.0E-7 T 23-10-2018 A3L04_04820 5ea636b39b4e5d8891e66df2225fc4f3 145 Gene3D G3DSA:3.30.300.20 74 144 2.5E-23 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L04_04820 5ea636b39b4e5d8891e66df2225fc4f3 145 Gene3D G3DSA:3.30.300.20 2 73 1.8E-26 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L04_04820 5ea636b39b4e5d8891e66df2225fc4f3 145 SUPERFAMILY SSF54814 12 74 1.96E-11 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L04_04820 5ea636b39b4e5d8891e66df2225fc4f3 145 SUPERFAMILY SSF54814 75 141 5.1E-7 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L04_04820 5ea636b39b4e5d8891e66df2225fc4f3 145 TIGRFAM TIGR01952 nusA_arch: NusA family KH domain protein, archaeal 1 145 2.1E-59 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal A3L04_04820 5ea636b39b4e5d8891e66df2225fc4f3 145 Pfam PF07650 KH domain 12 93 5.7E-17 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_04820 5ea636b39b4e5d8891e66df2225fc4f3 145 Hamap MF_00945_A Transcription termination/antitermination protein NusA [nusA]. 1 145 30.503 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal A3L04_08355 7c5402f9e7528f3f1a012a9acc61cf47 324 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 226 317 5.0E-24 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L04_08355 7c5402f9e7528f3f1a012a9acc61cf47 324 Gene3D G3DSA:3.40.50.300 1 323 9.4E-100 T 23-10-2018 A3L04_08355 7c5402f9e7528f3f1a012a9acc61cf47 324 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 228 287 1.7E-18 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L04_08355 7c5402f9e7528f3f1a012a9acc61cf47 324 SMART SM00382 31 226 6.6E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_08355 7c5402f9e7528f3f1a012a9acc61cf47 324 SUPERFAMILY SSF52540 2 248 2.15E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_08355 7c5402f9e7528f3f1a012a9acc61cf47 324 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_08355 7c5402f9e7528f3f1a012a9acc61cf47 324 Pfam PF00005 ABC transporter 23 177 1.9E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_01705 e801864b4ddfe4d6f7312af5942c78db 131 Pfam PF03686 Uncharacterised protein family (UPF0146) 3 127 3.3E-32 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 A3L04_01705 e801864b4ddfe4d6f7312af5942c78db 131 SUPERFAMILY SSF53335 11 107 2.16E-5 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_01705 e801864b4ddfe4d6f7312af5942c78db 131 Hamap MF_00341 UPF0146 protein . 1 130 27.279 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 A3L04_01705 e801864b4ddfe4d6f7312af5942c78db 131 Gene3D G3DSA:3.40.50.150 1 131 3.1E-29 T 23-10-2018 A3L04_01705 e801864b4ddfe4d6f7312af5942c78db 131 PIRSF PIRSF016725 1 130 1.6E-29 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 A3L04_01705 e801864b4ddfe4d6f7312af5942c78db 131 ProDom PD021130 UPF0146 MJ0688 SIMILAR ARCHAEA UNCHARACTERIZED AF0739.1 MTH1000 PYRAB01940 PH0209 VNG2609C 17 110 1.0E-28 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 A3L04_08985 9a28d78cd1d0ce6df68817227fc8e9e2 337 SUPERFAMILY SSF51726 7 324 1.12E-75 T 23-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A3L04_08985 9a28d78cd1d0ce6df68817227fc8e9e2 337 Hamap MF_00288 Methionine synthase [metE]. 5 317 48.127 T 23-10-2018 IPR022921 Methionine synthase MetE, archaeal GO:0008168|GO:0009086 A3L04_08985 9a28d78cd1d0ce6df68817227fc8e9e2 337 Gene3D G3DSA:3.20.20.210 1 323 1.2E-101 T 23-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A3L04_08985 9a28d78cd1d0ce6df68817227fc8e9e2 337 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 5 315 1.1E-54 T 23-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A3L04_02075 510ab6d6ea320722377659feaa8415eb 940 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 115 303 3.2E-15 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain A3L04_02075 510ab6d6ea320722377659feaa8415eb 940 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 919 938 1.7E-7 T 23-10-2018 IPR027552 CGP-CTERM domain A3L04_02075 510ab6d6ea320722377659feaa8415eb 940 Gene3D G3DSA:3.10.105.10 115 357 2.8E-20 T 23-10-2018 A3L04_02075 510ab6d6ea320722377659feaa8415eb 940 SUPERFAMILY SSF53850 117 306 7.6E-18 T 23-10-2018 A3L04_04595 90b7d77392e7b82bfd93496ef03b081b 182 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 86 121 - T 23-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A3L04_04595 90b7d77392e7b82bfd93496ef03b081b 182 PIRSF PIRSF006019 12 169 8.0E-57 T 23-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A3L04_04595 90b7d77392e7b82bfd93496ef03b081b 182 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 21 132 2.9E-29 T 23-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A3L04_04595 90b7d77392e7b82bfd93496ef03b081b 182 Gene3D G3DSA:3.40.140.10 18 167 1.6E-48 T 23-10-2018 A3L04_04595 90b7d77392e7b82bfd93496ef03b081b 182 SUPERFAMILY SSF53927 22 153 2.01E-40 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A3L04_04745 d58738430da8f3c074735bafcffcc155 166 Pfam PF01842 ACT domain 106 158 1.2E-6 T 23-10-2018 IPR002912 ACT domain A3L04_04745 d58738430da8f3c074735bafcffcc155 166 Gene3D G3DSA:3.30.70.260 104 165 5.7E-5 T 23-10-2018 A3L04_04745 d58738430da8f3c074735bafcffcc155 166 SUPERFAMILY SSF55021 106 164 2.71E-8 T 23-10-2018 A3L04_04745 d58738430da8f3c074735bafcffcc155 166 PIRSF PIRSF004897 1 166 2.9E-73 T 23-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type A3L04_03080 df5ddc55af823a56577618ece6b18a6d 172 SUPERFAMILY SSF53155 1 89 4.71E-23 T 23-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A3L04_03080 df5ddc55af823a56577618ece6b18a6d 172 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 140 146 - T 23-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A3L04_03080 df5ddc55af823a56577618ece6b18a6d 172 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 93 169 5.6E-21 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A3L04_03080 df5ddc55af823a56577618ece6b18a6d 172 ProDom PD068053 METHYLTRANSFERASE DNA METHYLATED-DNA--PROTEIN-CYSTEINE 6-O- O-6-METHYLGUANINE-DNA- REPAIR MGMT DAMAGE ALKYLTRANSFERASE METHYLGUANINE-DNA 1 97 2.0E-21 T 23-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 A3L04_03080 df5ddc55af823a56577618ece6b18a6d 172 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 91 168 8.9E-23 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A3L04_03080 df5ddc55af823a56577618ece6b18a6d 172 SUPERFAMILY SSF46767 91 169 2.35E-20 T 23-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 A3L04_03080 df5ddc55af823a56577618ece6b18a6d 172 Pfam PF09153 Domain of unknown function (DUF1938) 1 86 2.6E-24 T 23-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 A3L04_03080 df5ddc55af823a56577618ece6b18a6d 172 Gene3D G3DSA:3.30.160.70 1 89 1.8E-12 T 23-10-2018 A3L04_03080 df5ddc55af823a56577618ece6b18a6d 172 Gene3D G3DSA:1.10.10.10 90 172 1.9E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_04205 e1ba683cce70ee29fecd9c8663168ac1 225 Gene3D G3DSA:3.60.15.10 2 225 7.5E-76 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_04205 e1ba683cce70ee29fecd9c8663168ac1 225 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 2 225 38.898 T 23-10-2018 IPR022877 Protein of unknown funcion UPF0173 A3L04_04205 e1ba683cce70ee29fecd9c8663168ac1 225 SMART SM00849 8 190 6.3E-19 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_04205 e1ba683cce70ee29fecd9c8663168ac1 225 SUPERFAMILY SSF56281 1 224 3.14E-41 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_04205 e1ba683cce70ee29fecd9c8663168ac1 225 Pfam PF13483 Beta-lactamase superfamily domain 3 190 8.0E-35 T 23-10-2018 A3L04_03705 e7175bb257966f3ed3fdde859a95a03e 242 Gene3D G3DSA:3.40.50.1000 3 203 2.3E-6 T 23-10-2018 IPR023214 HAD superfamily A3L04_03705 e7175bb257966f3ed3fdde859a95a03e 242 SUPERFAMILY SSF56784 3 208 2.1E-14 T 23-10-2018 IPR036412 HAD-like superfamily A3L04_03705 e7175bb257966f3ed3fdde859a95a03e 242 Gene3D G3DSA:1.10.150.240 15 115 2.3E-6 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A3L04_07720 02483afd7cc49d848944a756a99030cc 202 Gene3D G3DSA:3.40.1280.10 1 201 1.1E-65 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L04_07720 02483afd7cc49d848944a756a99030cc 202 Pfam PF04013 Putative SAM-dependent RNA methyltransferase 1 199 1.1E-48 T 23-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 A3L04_07720 02483afd7cc49d848944a756a99030cc 202 SUPERFAMILY SSF75217 1 200 7.24E-62 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L04_07720 02483afd7cc49d848944a756a99030cc 202 Hamap MF_00587 tRNA (pseudouridine(54)-N(1))-methyltransferase [trmY]. 1 200 36.389 T 23-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 A3L04_10165 2a13d51583898559cec62112ecddbafb 139 SUPERFAMILY SSF101307 3 133 6.15E-34 T 23-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 A3L04_10165 2a13d51583898559cec62112ecddbafb 139 TIGRFAM TIGR03161 ribazole_CobZ: alpha-ribazole phosphatase CobZ 7 133 4.5E-51 T 23-10-2018 IPR017577 Alpha-ribazole phosphatase, CobZ A3L04_10165 2a13d51583898559cec62112ecddbafb 139 Pfam PF04608 Phosphatidylglycerophosphatase A 13 132 1.8E-9 T 23-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A3L04_10165 2a13d51583898559cec62112ecddbafb 139 Gene3D G3DSA:1.10.3760.10 1 139 6.1E-14 T 23-10-2018 A3L04_00860 61d06f938b6b82524c41f276f4286b85 237 PIRSF PIRSF016933 4 226 3.5E-33 T 23-10-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 A3L04_00860 61d06f938b6b82524c41f276f4286b85 237 Pfam PF13367 Protease prsW family 31 202 1.5E-30 T 23-10-2018 IPR026898 Protease PrsW GO:0008233 A3L04_02530 7ac9e980e23c5cd7f40ba636ba17a0d5 194 PIRSF PIRSF004897 1 165 5.4E-64 T 23-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type A3L04_09205 f09f7c22522841b922e104982a866001 138 Gene3D G3DSA:3.30.1330.80 1 137 1.7E-45 T 23-10-2018 A3L04_09205 f09f7c22522841b922e104982a866001 138 PIRSF PIRSF016702 1 138 8.6E-41 T 23-10-2018 IPR025707 Predicted DNA-binding protein with PD1-like DNA-binding motif A3L04_09205 f09f7c22522841b922e104982a866001 138 Pfam PF03479 Domain of unknown function (DUF296) 6 116 1.9E-19 T 23-10-2018 IPR005175 PPC domain A3L04_09205 f09f7c22522841b922e104982a866001 138 SUPERFAMILY SSF117856 3 126 6.02E-32 T 23-10-2018 A3L04_07215 9da392b46356e272e3f652ee5f9156eb 206 Pfam PF04021 Class III signal peptide 2 24 1.3E-7 T 23-10-2018 IPR007166 Class III signal peptide motif A3L04_04340 7295a3f7d07bcd82838871eec8706b6c 148 SUPERFAMILY SSF46946 8 147 6.56E-36 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A3L04_04340 7295a3f7d07bcd82838871eec8706b6c 148 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 7 147 26.118 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_04340 7295a3f7d07bcd82838871eec8706b6c 148 ProSitePatterns PS00646 Ribosomal protein S13 signature. 116 129 - T 23-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_04340 7295a3f7d07bcd82838871eec8706b6c 148 PIRSF PIRSF002134 1 148 6.5E-43 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_04340 7295a3f7d07bcd82838871eec8706b6c 148 Pfam PF00416 Ribosomal protein S13/S18 9 137 1.5E-41 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_04340 7295a3f7d07bcd82838871eec8706b6c 148 Gene3D G3DSA:4.10.910.10 87 138 1.4E-22 T 23-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_04340 7295a3f7d07bcd82838871eec8706b6c 148 TIGRFAM TIGR03629 uS13_arch: ribosomal protein uS13 3 147 5.5E-64 T 23-10-2018 IPR019977 Ribosomal protein S13, archaeal GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_04340 7295a3f7d07bcd82838871eec8706b6c 148 Gene3D G3DSA:1.10.8.50 1 75 3.3E-26 T 23-10-2018 A3L04_04730 aacb36426c19ec879650f2a80c078fc0 455 Pfam PF01523 Putative modulator of DNA gyrase 19 310 1.1E-46 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L04_04730 aacb36426c19ec879650f2a80c078fc0 455 PIRSF PIRSF004919 1 455 1.3E-155 T 23-10-2018 IPR025502 TldD A3L04_04730 aacb36426c19ec879650f2a80c078fc0 455 Gene3D G3DSA:3.30.2290.10 1 204 3.9E-17 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L04_04730 aacb36426c19ec879650f2a80c078fc0 455 SUPERFAMILY SSF111283 2 450 7.85E-98 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L04_02335 b2610d5c4d17667883bdad86de06c5f7 396 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 170 344 2.9E-21 T 23-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 A3L04_02335 b2610d5c4d17667883bdad86de06c5f7 396 Gene3D G3DSA:3.40.50.150 179 396 8.1E-75 T 23-10-2018 A3L04_02335 b2610d5c4d17667883bdad86de06c5f7 396 Gene3D G3DSA:3.30.750.80 72 178 4.4E-39 T 23-10-2018 A3L04_02335 b2610d5c4d17667883bdad86de06c5f7 396 Gene3D G3DSA:2.30.130.10 1 71 2.8E-22 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L04_02335 b2610d5c4d17667883bdad86de06c5f7 396 SMART SM00359 2 87 2.8E-25 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L04_02335 b2610d5c4d17667883bdad86de06c5f7 396 Pfam PF01472 PUA domain 3 74 2.9E-15 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L04_02335 b2610d5c4d17667883bdad86de06c5f7 396 SUPERFAMILY SSF88697 1 69 1.64E-17 T 23-10-2018 IPR015947 PUA-like superfamily A3L04_02335 b2610d5c4d17667883bdad86de06c5f7 396 SUPERFAMILY SSF53335 78 390 2.16E-72 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_06495 f01b54792f82a4439be095034b5aed00 93 Gene3D G3DSA:1.20.120.460 1 93 9.0E-40 T 23-10-2018 IPR038317 Pf1176-like superfamily A3L04_06495 f01b54792f82a4439be095034b5aed00 93 Pfam PF11505 Protein of unknown function (DUF3216) 4 91 6.8E-32 T 23-10-2018 IPR023108 Domain of unknown function, DUF3216 A3L04_04190 87f5e2fa1ffb5f4619ae07f5b35149f2 374 Gene3D G3DSA:3.40.50.12090 30 123 4.3E-6 T 23-10-2018 A3L04_03505 a45acffe0fdc9eb9e82c9da735eee7ff 175 SMART SM01415 10 174 9.3E-15 T 23-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 A3L04_03505 a45acffe0fdc9eb9e82c9da735eee7ff 175 Pfam PF01956 Integral membrane protein DUF106 13 173 1.0E-25 T 23-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 A3L04_10110 70bdb75c738bf1ba6a4e11bc3d85557b 166 Pfam PF01927 Mut7-C RNAse domain 1 145 1.0E-45 T 23-10-2018 IPR002782 Mut7-C RNAse domain A3L04_10110 70bdb75c738bf1ba6a4e11bc3d85557b 166 SUPERFAMILY SSF88723 28 67 2.65E-6 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_10110 70bdb75c738bf1ba6a4e11bc3d85557b 166 Gene3D G3DSA:3.40.50.1010 5 71 9.1E-7 T 23-10-2018 A3L04_09155 141575eb807ecae924a61e9714a68c05 70 Pfam PF11755 Protein of unknown function (DUF3311) 13 63 3.8E-10 T 23-10-2018 IPR021741 Protein of unknown function DUF3311 A3L04_05100 df16309543103dc93e4316dbe97ce7d4 425 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 1 425 86.811 T 23-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A3L04_05100 df16309543103dc93e4316dbe97ce7d4 425 Pfam PF01964 Radical SAM ThiC family 2 420 6.4E-180 T 23-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A3L04_05100 df16309543103dc93e4316dbe97ce7d4 425 Gene3D G3DSA:3.20.20.540 43 362 5.8E-137 T 23-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A3L04_05100 df16309543103dc93e4316dbe97ce7d4 425 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 1 422 1.7E-183 T 23-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A3L04_07120 7e29e07a54b0c5eac4489b62d4ef72de 665 SMART SM00926 5 55 1.6E-10 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07120 7e29e07a54b0c5eac4489b62d4ef72de 665 Gene3D G3DSA:3.40.50.740 64 522 7.0E-173 T 23-10-2018 A3L04_07120 7e29e07a54b0c5eac4489b62d4ef72de 665 SUPERFAMILY SSF53706 7 560 2.88E-197 T 23-10-2018 A3L04_07120 7e29e07a54b0c5eac4489b62d4ef72de 665 Pfam PF01568 Molydopterin dinucleotide binding domain 558 656 2.2E-23 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A3L04_07120 7e29e07a54b0c5eac4489b62d4ef72de 665 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 7 53 6.4E-9 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07120 7e29e07a54b0c5eac4489b62d4ef72de 665 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 10 662 1.4E-283 T 23-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 A3L04_07120 7e29e07a54b0c5eac4489b62d4ef72de 665 Gene3D G3DSA:2.40.40.20 548 665 3.6E-34 T 23-10-2018 A3L04_07120 7e29e07a54b0c5eac4489b62d4ef72de 665 Pfam PF00384 Molybdopterin oxidoreductase 58 479 5.7E-94 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07120 7e29e07a54b0c5eac4489b62d4ef72de 665 Gene3D G3DSA:3.40.228.10 135 332 7.0E-173 T 23-10-2018 A3L04_07120 7e29e07a54b0c5eac4489b62d4ef72de 665 Gene3D G3DSA:2.20.25.90 5 57 2.3E-10 T 23-10-2018 A3L04_07120 7e29e07a54b0c5eac4489b62d4ef72de 665 SUPERFAMILY SSF50692 530 664 1.27E-38 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L04_06270 e008c19587abc063efc10ca06ab3b0ab 275 Gene3D G3DSA:3.20.20.70 11 269 3.2E-16 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_06270 e008c19587abc063efc10ca06ab3b0ab 275 SMART SM00729 13 216 0.0015 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L04_06270 e008c19587abc063efc10ca06ab3b0ab 275 Pfam PF04055 Radical SAM superfamily 18 159 1.4E-7 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_06270 e008c19587abc063efc10ca06ab3b0ab 275 SUPERFAMILY SSF102114 10 250 2.75E-25 T 23-10-2018 A3L04_08500 ce33403699b5e18eae5ac0f7d7e6943e 1129 Pfam PF04465 Protein of unknown function (DUF499) 110 1125 3.7E-248 T 23-10-2018 IPR007555 Protein of unknown function DUF499 A3L04_01250 f294d7b7e0b5edda4d9e90b8a6333eb6 256 Gene3D G3DSA:3.40.50.150 64 252 2.2E-43 T 23-10-2018 A3L04_01250 f294d7b7e0b5edda4d9e90b8a6333eb6 256 SUPERFAMILY SSF53335 35 220 1.3E-23 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_01250 f294d7b7e0b5edda4d9e90b8a6333eb6 256 Pfam PF05971 Protein of unknown function (DUF890) 15 162 5.7E-11 T 23-10-2018 IPR010286 Ribosomal RNA large subunit methyltransferase F-like GO:0008168 A3L04_03660 b0a53839a080fbeb000410a1bfd38c26 307 Pfam PF06195 Protein of unknown function (DUF996) 33 166 6.1E-10 T 23-10-2018 IPR010397 Protein of unknown function DUF996 A3L04_01475 2cc1021d39b7fc590d995c7312637d62 210 SMART SM00849 7 174 1.1E-22 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_01475 2cc1021d39b7fc590d995c7312637d62 210 Gene3D G3DSA:3.60.15.10 1 202 2.3E-50 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_01475 2cc1021d39b7fc590d995c7312637d62 210 Pfam PF13483 Beta-lactamase superfamily domain 2 174 1.4E-32 T 23-10-2018 A3L04_01475 2cc1021d39b7fc590d995c7312637d62 210 SUPERFAMILY SSF56281 1 197 8.12E-38 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_06895 d2fb478b32ce33e8ea35c8f02be5e1b5 217 Pfam PF00753 Metallo-beta-lactamase superfamily 42 139 6.1E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_06895 d2fb478b32ce33e8ea35c8f02be5e1b5 217 Gene3D G3DSA:3.60.15.10 114 217 8.7E-19 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_06895 d2fb478b32ce33e8ea35c8f02be5e1b5 217 SUPERFAMILY SSF56281 20 191 5.5E-21 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_06895 d2fb478b32ce33e8ea35c8f02be5e1b5 217 Gene3D G3DSA:3.60.15.10 1 97 1.4E-17 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_06895 d2fb478b32ce33e8ea35c8f02be5e1b5 217 SMART SM00849 17 188 0.0095 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L04_09910 45b1381c3cecad6d222d3d6fb6ea3520 517 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 92 107 - T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L04_09910 45b1381c3cecad6d222d3d6fb6ea3520 517 PRINTS PR00175 Sodium/alanine symporter signature 363 381 4.2E-54 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L04_09910 45b1381c3cecad6d222d3d6fb6ea3520 517 PRINTS PR00175 Sodium/alanine symporter signature 272 291 4.2E-54 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L04_09910 45b1381c3cecad6d222d3d6fb6ea3520 517 PRINTS PR00175 Sodium/alanine symporter signature 92 114 4.2E-54 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L04_09910 45b1381c3cecad6d222d3d6fb6ea3520 517 PRINTS PR00175 Sodium/alanine symporter signature 244 262 4.2E-54 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L04_09910 45b1381c3cecad6d222d3d6fb6ea3520 517 PRINTS PR00175 Sodium/alanine symporter signature 409 431 4.2E-54 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L04_09910 45b1381c3cecad6d222d3d6fb6ea3520 517 PRINTS PR00175 Sodium/alanine symporter signature 481 501 4.2E-54 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L04_09910 45b1381c3cecad6d222d3d6fb6ea3520 517 Pfam PF01235 Sodium:alanine symporter family 206 514 4.7E-97 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L04_09910 45b1381c3cecad6d222d3d6fb6ea3520 517 Pfam PF01235 Sodium:alanine symporter family 55 166 2.3E-35 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L04_09910 45b1381c3cecad6d222d3d6fb6ea3520 517 TIGRFAM TIGR00835 agcS: amino acid carrier protein 206 511 9.6E-90 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L04_01370 7175f79fa2ff94cd81566630f68818b5 179 Pfam PF06197 Protein of unknown function (DUF998) 7 174 7.8E-20 T 23-10-2018 IPR009339 Protein of unknown function DUF998 A3L04_03020 b69abf31914dbbaf5b52c393bad8cf4b 501 SMART SM00283 223 498 1.2E-55 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A3L04_03020 b69abf31914dbbaf5b52c393bad8cf4b 501 SUPERFAMILY SSF58104 162 495 1.48E-59 T 23-10-2018 A3L04_03020 b69abf31914dbbaf5b52c393bad8cf4b 501 Gene3D G3DSA:1.10.287.950 191 498 9.8E-65 T 23-10-2018 A3L04_03020 b69abf31914dbbaf5b52c393bad8cf4b 501 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 277 425 2.0E-36 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A3L04_03020 b69abf31914dbbaf5b52c393bad8cf4b 501 Gene3D G3DSA:1.20.1480.50 48 153 6.6E-9 T 23-10-2018 A3L04_03020 b69abf31914dbbaf5b52c393bad8cf4b 501 SMART SM00304 91 149 0.011 T 23-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A3L04_03020 b69abf31914dbbaf5b52c393bad8cf4b 501 SMART SM00304 183 240 3.1 T 23-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A3L04_07095 368c39915c48ccd5b99d22c0412a7954 250 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 26 48 4.7E-8 T 23-10-2018 A3L04_07095 368c39915c48ccd5b99d22c0412a7954 250 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 159 174 4.7E-8 T 23-10-2018 A3L04_07095 368c39915c48ccd5b99d22c0412a7954 250 Gene3D G3DSA:3.50.50.60 1 250 1.7E-104 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_07095 368c39915c48ccd5b99d22c0412a7954 250 TIGRFAM TIGR00292 TIGR00292: thiazole biosynthesis enzyme 6 250 7.5E-99 T 23-10-2018 IPR002922 Thiazole biosynthetic enzyme Thi4 family A3L04_07095 368c39915c48ccd5b99d22c0412a7954 250 Hamap MF_00304 Thiamine thiazole synthase [thi4]. 2 250 44.389 T 23-10-2018 IPR022828 Thiazole biosynthetic enzyme, prokaryotic A3L04_07095 368c39915c48ccd5b99d22c0412a7954 250 SUPERFAMILY SSF51905 4 247 1.04E-50 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_07095 368c39915c48ccd5b99d22c0412a7954 250 Pfam PF01946 Thi4 family 8 232 2.8E-85 T 23-10-2018 A3L04_10385 84dd3808587a1408ff7e1b9dcdf1d038 328 Pfam PF00534 Glycosyl transferases group 1 169 294 2.7E-24 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L04_10385 84dd3808587a1408ff7e1b9dcdf1d038 328 SUPERFAMILY SSF53756 4 327 6.0E-66 T 23-10-2018 A3L04_10385 84dd3808587a1408ff7e1b9dcdf1d038 328 Gene3D G3DSA:3.40.50.2000 164 302 1.3E-32 T 23-10-2018 A3L04_10385 84dd3808587a1408ff7e1b9dcdf1d038 328 Pfam PF13439 Glycosyltransferase Family 4 14 161 1.0E-25 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L04_10385 84dd3808587a1408ff7e1b9dcdf1d038 328 Gene3D G3DSA:3.40.50.2000 1 163 5.8E-36 T 23-10-2018 A3L04_09055 75b5bd7141e51d1b3e2c17abccfb8eb4 240 TIGRFAM TIGR01881 cas_Cmr5: CRISPR type III-B/RAMP module-associated protein Cmr5 65 159 3.9E-13 T 23-10-2018 IPR010160 CRISPR-associated protein, Cmr5 A3L04_09055 75b5bd7141e51d1b3e2c17abccfb8eb4 240 TIGRFAM TIGR01881 cas_Cmr5: CRISPR type III-B/RAMP module-associated protein Cmr5 148 240 6.3E-9 T 23-10-2018 IPR010160 CRISPR-associated protein, Cmr5 A3L04_09055 75b5bd7141e51d1b3e2c17abccfb8eb4 240 SUPERFAMILY SSF158568 3 238 9.68E-23 T 23-10-2018 IPR023101 AF1862-like domain superfamily A3L04_09055 75b5bd7141e51d1b3e2c17abccfb8eb4 240 Pfam PF09701 CRISPR-associated protein (Cas_Cmr5) 7 236 2.4E-20 T 23-10-2018 IPR010160 CRISPR-associated protein, Cmr5 A3L04_09055 75b5bd7141e51d1b3e2c17abccfb8eb4 240 Gene3D G3DSA:1.10.520.30 140 240 9.8E-16 T 23-10-2018 IPR023101 AF1862-like domain superfamily A3L04_09055 75b5bd7141e51d1b3e2c17abccfb8eb4 240 Gene3D G3DSA:1.10.520.30 52 139 1.3E-12 T 23-10-2018 IPR023101 AF1862-like domain superfamily A3L04_06545 4568d8e80a36fe36ad48a070e84f46fc 446 SUPERFAMILY SSF53613 5 263 2.18E-82 T 23-10-2018 IPR029056 Ribokinase-like A3L04_06545 4568d8e80a36fe36ad48a070e84f46fc 446 SUPERFAMILY SSF53639 267 445 7.46E-66 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L04_06545 4568d8e80a36fe36ad48a070e84f46fc 446 Pfam PF10120 Thiamine-phosphate synthase 274 443 3.5E-64 T 23-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L04_06545 4568d8e80a36fe36ad48a070e84f46fc 446 Pfam PF08543 Phosphomethylpyrimidine kinase 14 257 3.0E-95 T 23-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 A3L04_06545 4568d8e80a36fe36ad48a070e84f46fc 446 Gene3D G3DSA:3.40.1190.20 3 266 2.8E-96 T 23-10-2018 IPR029056 Ribokinase-like A3L04_06545 4568d8e80a36fe36ad48a070e84f46fc 446 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 7 258 3.0E-106 T 23-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L04_06545 4568d8e80a36fe36ad48a070e84f46fc 446 Gene3D G3DSA:3.40.225.10 267 446 3.3E-79 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L04_03925 0d1618baab8942a5fc6df9eb206d1ec6 387 Gene3D G3DSA:3.40.50.1100 48 377 6.7E-192 T 23-10-2018 A3L04_03925 0d1618baab8942a5fc6df9eb206d1ec6 387 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 1 384 52.885 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L04_03925 0d1618baab8942a5fc6df9eb206d1ec6 387 Gene3D G3DSA:3.40.50.1100 4 200 6.7E-192 T 23-10-2018 A3L04_03925 0d1618baab8942a5fc6df9eb206d1ec6 387 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 3 382 3.4E-195 T 23-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L04_03925 0d1618baab8942a5fc6df9eb206d1ec6 387 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 75 89 - T 23-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L04_03925 0d1618baab8942a5fc6df9eb206d1ec6 387 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 48 371 2.0E-49 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L04_03925 0d1618baab8942a5fc6df9eb206d1ec6 387 SUPERFAMILY SSF53686 2 381 2.49E-147 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L04_03925 0d1618baab8942a5fc6df9eb206d1ec6 387 PIRSF PIRSF001413 3 386 4.1E-169 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L04_08095 6bf1b8caa7c04f5a52c3170a64ebe48c 154 PRINTS PR00446 Hydrogen uptake protein signature 13 25 1.1E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L04_08095 6bf1b8caa7c04f5a52c3170a64ebe48c 154 PRINTS PR00446 Hydrogen uptake protein signature 25 36 1.1E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L04_08095 6bf1b8caa7c04f5a52c3170a64ebe48c 154 PRINTS PR00446 Hydrogen uptake protein signature 67 77 1.1E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L04_08095 6bf1b8caa7c04f5a52c3170a64ebe48c 154 Pfam PF01750 Hydrogenase maturation protease 32 151 1.3E-20 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L04_08095 6bf1b8caa7c04f5a52c3170a64ebe48c 154 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 14 152 8.9E-35 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L04_08095 6bf1b8caa7c04f5a52c3170a64ebe48c 154 Gene3D G3DSA:3.40.50.1450 9 153 3.0E-44 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L04_08095 6bf1b8caa7c04f5a52c3170a64ebe48c 154 TIGRFAM TIGR00142 hycI: hydrogenase maturation peptidase HycI 14 153 2.3E-35 T 23-10-2018 IPR004420 Peptidase A31, hydrogenase maturation protease HycI GO:0008233 A3L04_08095 6bf1b8caa7c04f5a52c3170a64ebe48c 154 SUPERFAMILY SSF53163 11 154 1.83E-32 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L04_10075 3a00047324e477590d8e036819e479a0 96 Gene3D G3DSA:2.20.28.10 1 96 2.3E-33 T 23-10-2018 A3L04_10075 3a00047324e477590d8e036819e479a0 96 SUPERFAMILY SSF46785 3 94 2.99E-34 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_08815 8d69a8bf011eb930898202c472fd4716 141 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 2 45 1.9E-12 T 23-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 A3L04_08815 8d69a8bf011eb930898202c472fd4716 141 Gene3D G3DSA:1.10.60.10 56 111 6.5E-20 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 A3L04_08815 8d69a8bf011eb930898202c472fd4716 141 Gene3D G3DSA:1.10.10.10 1 55 5.1E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_08815 8d69a8bf011eb930898202c472fd4716 141 SUPERFAMILY SSF47979 51 123 6.67E-19 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 A3L04_08815 8d69a8bf011eb930898202c472fd4716 141 SMART SM00529 12 111 3.1E-47 T 23-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 A3L04_08815 8d69a8bf011eb930898202c472fd4716 141 SUPERFAMILY SSF46785 2 74 5.4E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_08815 8d69a8bf011eb930898202c472fd4716 141 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 51 116 1.1E-21 T 23-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 A3L04_10120 02d19d487d386bc63c8db3012733ddf0 86 Pfam PF03683 Uncharacterised protein family (UPF0175) 8 81 5.6E-27 T 23-10-2018 IPR005368 Uncharacterised protein family UPF0175 A3L04_06230 881e225d9966bdbcebf4f3794aaef65e 104 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 6 98 8.1E-32 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L04_06230 881e225d9966bdbcebf4f3794aaef65e 104 Pfam PF03334 Na+/H+ antiporter subunit 7 86 2.6E-23 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L04_10140 51e6e95673d3d3402475fa90f60bdf61 135 SUPERFAMILY SSF88723 2 131 1.35E-17 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_10140 51e6e95673d3d3402475fa90f60bdf61 135 Pfam PF01850 PIN domain 2 124 1.6E-11 T 23-10-2018 IPR002716 PIN domain A3L04_10140 51e6e95673d3d3402475fa90f60bdf61 135 Gene3D G3DSA:3.40.50.1010 1 127 4.6E-25 T 23-10-2018 A3L04_09660 d38cf1c6c1114c3f5f19168d11250e53 348 SUPERFAMILY SSF102114 2 253 1.7E-29 T 23-10-2018 A3L04_09660 d38cf1c6c1114c3f5f19168d11250e53 348 Pfam PF04055 Radical SAM superfamily 10 121 1.2E-11 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_00305 877b4875482f52040a9474f2df13348a 248 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 12 216 3.0E-35 T 23-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A3L04_00305 877b4875482f52040a9474f2df13348a 248 Gene3D G3DSA:3.20.20.190 1 248 3.6E-94 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A3L04_00305 877b4875482f52040a9474f2df13348a 248 SUPERFAMILY SSF51695 6 214 8.37E-59 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A3L04_01300 673b68c192784c26d33e151ec20d03f1 198 SUPERFAMILY SSF52402 2 152 1.23E-23 T 23-10-2018 A3L04_01300 673b68c192784c26d33e151ec20d03f1 198 Gene3D G3DSA:3.40.50.620 1 198 2.9E-67 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_01300 673b68c192784c26d33e151ec20d03f1 198 Pfam PF00733 Asparagine synthase 6 73 3.2E-5 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A3L04_07615 f7dbc5bdd1a1e6bb544391fa3bdbed7e 122 Pfam PF03334 Na+/H+ antiporter subunit 10 99 2.7E-24 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L04_07615 f7dbc5bdd1a1e6bb544391fa3bdbed7e 122 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 10 113 9.0E-36 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L04_06285 88f6fdeb97a6440685e894d75dca982a 228 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 195 6.6E-25 T 23-10-2018 A3L04_06285 88f6fdeb97a6440685e894d75dca982a 228 Gene3D G3DSA:3.40.50.1000 3 217 1.2E-41 T 23-10-2018 IPR023214 HAD superfamily A3L04_06285 88f6fdeb97a6440685e894d75dca982a 228 Gene3D G3DSA:1.10.150.520 14 96 1.2E-41 T 23-10-2018 A3L04_06285 88f6fdeb97a6440685e894d75dca982a 228 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 91 188 2.2E-10 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L04_06285 88f6fdeb97a6440685e894d75dca982a 228 SUPERFAMILY SSF56784 3 223 5.15E-37 T 23-10-2018 IPR036412 HAD-like superfamily A3L04_07360 ecc7748a56ef3a2a62135216a7ff9efe 133 Pfam PF04475 Protein of unknown function (DUF555) 3 104 1.3E-36 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A3L04_07360 ecc7748a56ef3a2a62135216a7ff9efe 133 PIRSF PIRSF016934 1 130 1.2E-52 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A3L04_07360 ecc7748a56ef3a2a62135216a7ff9efe 133 ProDom PD020367 UPF0212 RRNAC1165 RRNAC0441 AF0282 VNG1264C MJ0068 PYRAB08340 PH1312 MA1372 TK1194 1 91 8.0E-42 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A3L04_07360 ecc7748a56ef3a2a62135216a7ff9efe 133 Hamap MF_01223 UPF0212 protein . 1 112 31.527 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A3L04_02505 9eb6dee80d3ebfe81208841b8e5fedc1 379 Pfam PF00999 Sodium/hydrogen exchanger family 9 377 4.1E-63 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L04_02505 9eb6dee80d3ebfe81208841b8e5fedc1 379 Gene3D G3DSA:1.20.1530.20 1 379 9.4E-97 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L04_04570 9eb2569daf5013abd4d52d598a3a9f08 426 Gene3D G3DSA:1.20.1530.20 4 410 3.1E-67 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L04_04570 9eb2569daf5013abd4d52d598a3a9f08 426 Pfam PF00999 Sodium/hydrogen exchanger family 10 398 5.4E-46 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L04_08435 71a9b540302f191d1955c9ed2dfc432a 134 Gene3D G3DSA:3.30.70.260 48 132 3.7E-12 T 23-10-2018 A3L04_08435 71a9b540302f191d1955c9ed2dfc432a 134 Pfam PF01842 ACT domain 58 119 1.2E-9 T 23-10-2018 IPR002912 ACT domain A3L04_08435 71a9b540302f191d1955c9ed2dfc432a 134 SUPERFAMILY SSF55021 57 131 5.34E-13 T 23-10-2018 A3L04_01730 11aa0a7b152974ad01c9780d18878623 394 SUPERFAMILY SSF52540 59 310 3.66E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01730 11aa0a7b152974ad01c9780d18878623 394 Gene3D G3DSA:3.40.50.300 42 218 1.6E-8 T 23-10-2018 A3L04_02350 5eebd72b50120385edec31081c3bc925 174 SUPERFAMILY SSF52402 34 173 3.35E-9 T 23-10-2018 A3L04_02350 5eebd72b50120385edec31081c3bc925 174 Gene3D G3DSA:3.40.50.620 35 174 6.0E-12 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_01845 d6d6125875662b230ec7f2ed3cf4872d 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 257 3.6E-50 T 23-10-2018 A3L04_01845 d6d6125875662b230ec7f2ed3cf4872d 263 Gene3D G3DSA:3.40.50.720 2 258 9.2E-65 T 23-10-2018 A3L04_01845 d6d6125875662b230ec7f2ed3cf4872d 263 SUPERFAMILY SSF51735 8 258 9.21E-67 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_01845 d6d6125875662b230ec7f2ed3cf4872d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 5.8E-27 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_01845 d6d6125875662b230ec7f2ed3cf4872d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 5.8E-27 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_01845 d6d6125875662b230ec7f2ed3cf4872d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 5.8E-27 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_01845 d6d6125875662b230ec7f2ed3cf4872d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 5.8E-27 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_01845 d6d6125875662b230ec7f2ed3cf4872d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 5.8E-27 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_04670 7f22fb4f3e45c9b7107a2adc55f966e9 338 Pfam PF01594 AI-2E family transporter 11 321 6.9E-31 T 23-10-2018 IPR002549 Transmembrane protein TqsA-like A3L04_01165 2d3b753be306b68f2cf496f016c00cf1 391 SUPERFAMILY SSF53743 30 265 2.88E-26 T 23-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 A3L04_09425 0f80412263541b86c802dc2c6dfa75da 152 SUPERFAMILY SSF57825 101 149 3.92E-17 T 23-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily A3L04_09425 0f80412263541b86c802dc2c6dfa75da 152 Gene3D G3DSA:2.30.30.20 99 152 9.2E-23 T 23-10-2018 A3L04_09425 0f80412263541b86c802dc2c6dfa75da 152 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 1 150 36.168 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 A3L04_09425 0f80412263541b86c802dc2c6dfa75da 152 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 2 150 2.1E-65 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 A3L04_09425 0f80412263541b86c802dc2c6dfa75da 152 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 6 98 2.0E-42 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal A3L04_09425 0f80412263541b86c802dc2c6dfa75da 152 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 102 148 4.5E-20 T 23-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal A3L04_09425 0f80412263541b86c802dc2c6dfa75da 152 SUPERFAMILY SSF54893 3 99 1.29E-34 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily A3L04_09425 0f80412263541b86c802dc2c6dfa75da 152 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 4 97 1.3E-35 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal A3L04_09425 0f80412263541b86c802dc2c6dfa75da 152 Gene3D G3DSA:3.30.70.140 1 98 2.2E-38 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily A3L04_03915 54d83c225569cce60e3227efb4c1f198 259 SUPERFAMILY SSF51735 1 146 4.7E-25 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_03915 54d83c225569cce60e3227efb4c1f198 259 Gene3D G3DSA:3.40.50.720 1 155 1.1E-27 T 23-10-2018 A3L04_03915 54d83c225569cce60e3227efb4c1f198 259 Pfam PF02153 Prephenate dehydrogenase 40 172 1.2E-13 T 23-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 A3L04_00710 8a70a2928e8f21f48fb886bd329c2fe1 352 SUPERFAMILY SSF53448 1 254 1.94E-44 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_00710 8a70a2928e8f21f48fb886bd329c2fe1 352 Gene3D G3DSA:3.90.550.10 1 240 1.8E-52 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_00710 8a70a2928e8f21f48fb886bd329c2fe1 352 Pfam PF00535 Glycosyl transferase family 2 4 168 6.7E-37 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L04_00710 8a70a2928e8f21f48fb886bd329c2fe1 352 Pfam PF04138 GtrA-like protein 236 351 7.4E-27 T 23-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 A3L04_01295 f33d2e796cb56f496b1dfd4712ae6585 143 SUPERFAMILY SSF52242 5 134 5.36E-50 T 23-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 A3L04_01295 f33d2e796cb56f496b1dfd4712ae6585 143 Gene3D G3DSA:3.40.50.280 1 142 4.3E-59 T 23-10-2018 A3L04_01295 f33d2e796cb56f496b1dfd4712ae6585 143 Pfam PF02310 B12 binding domain 8 121 1.2E-24 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A3L04_01295 f33d2e796cb56f496b1dfd4712ae6585 143 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 6 138 9.0E-63 T 23-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L04_00505 9c3509044a38cf81706e8e169bd81eb4 463 Gene3D G3DSA:1.20.58.100 368 458 9.3E-20 T 23-10-2018 A3L04_00505 9c3509044a38cf81706e8e169bd81eb4 463 SUPERFAMILY SSF56425 204 307 1.94E-33 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L04_00505 9c3509044a38cf81706e8e169bd81eb4 463 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 1 445 6.7E-169 T 23-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L04_00505 9c3509044a38cf81706e8e169bd81eb4 463 Gene3D G3DSA:3.90.700.10 212 301 1.5E-110 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L04_00505 9c3509044a38cf81706e8e169bd81eb4 463 Gene3D G3DSA:3.50.50.60 5 353 1.5E-110 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_00505 9c3509044a38cf81706e8e169bd81eb4 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 324 331 1.4E-6 T 23-10-2018 A3L04_00505 9c3509044a38cf81706e8e169bd81eb4 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 166 175 1.4E-6 T 23-10-2018 A3L04_00505 9c3509044a38cf81706e8e169bd81eb4 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 1.4E-6 T 23-10-2018 A3L04_00505 9c3509044a38cf81706e8e169bd81eb4 463 Pfam PF00890 FAD binding domain 3 346 8.3E-70 T 23-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L04_00505 9c3509044a38cf81706e8e169bd81eb4 463 SUPERFAMILY SSF51905 1 367 5.77E-48 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_00505 9c3509044a38cf81706e8e169bd81eb4 463 SUPERFAMILY SSF46977 384 453 7.85E-21 T 23-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L04_00505 9c3509044a38cf81706e8e169bd81eb4 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 5.7E-11 T 23-10-2018 A3L04_00505 9c3509044a38cf81706e8e169bd81eb4 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 309 331 5.7E-11 T 23-10-2018 A3L04_00505 9c3509044a38cf81706e8e169bd81eb4 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 5.7E-11 T 23-10-2018 A3L04_00505 9c3509044a38cf81706e8e169bd81eb4 463 Pfam PF02910 Fumarate reductase flavoprotein C-term 420 454 6.2E-8 T 23-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L04_04120 415dacb556bac7ce05c1ed442ffcffa0 533 Gene3D G3DSA:2.130.10.10 14 324 1.8E-5 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A3L04_04120 415dacb556bac7ce05c1ed442ffcffa0 533 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 513 532 1.0E-4 T 23-10-2018 IPR027552 CGP-CTERM domain A3L04_05860 6aed3d2aa4be218fb40ab49e17333e58 331 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 57 218 3.0E-25 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L04_05860 6aed3d2aa4be218fb40ab49e17333e58 331 Gene3D G3DSA:3.40.50.970 14 98 2.8E-11 T 23-10-2018 A3L04_05860 6aed3d2aa4be218fb40ab49e17333e58 331 Gene3D G3DSA:3.40.50.970 99 321 3.6E-68 T 23-10-2018 A3L04_05860 6aed3d2aa4be218fb40ab49e17333e58 331 SUPERFAMILY SSF52518 12 318 2.03E-76 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L04_07150 d682a643213ecef49764f0f2916b90a4 116 Pfam PF13173 AAA domain 2 114 5.4E-28 T 23-10-2018 A3L04_07150 d682a643213ecef49764f0f2916b90a4 116 SUPERFAMILY SSF52540 11 115 2.02E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_02680 523d0ab488e2e660e179417984f3b75a 1207 Gene3D G3DSA:2.60.120.260 875 1035 3.3E-18 T 23-10-2018 IPR008979 Galactose-binding-like domain superfamily A3L04_03265 4a12b66467f326cc2e5c7f06d91d8308 109 Pfam PF03788 LrgA family 17 103 2.3E-27 T 23-10-2018 IPR005538 LrgA/CidA family GO:0016021 A3L04_04795 d07e4e2d6bd02a7aa740075eee9f1be3 82 ProDom PD005155 RNA POLYMERASE DNA-DIRECTED SUBUNIT NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION II H POLYPEPTIDE 14 79 8.0E-30 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L04_04795 d07e4e2d6bd02a7aa740075eee9f1be3 82 Hamap MF_00025 DNA-directed RNA polymerase subunit H [rpoH]. 7 80 22.901 T 23-10-2018 IPR020609 Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L04_04795 d07e4e2d6bd02a7aa740075eee9f1be3 82 SUPERFAMILY SSF55287 7 80 1.7E-28 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L04_04795 d07e4e2d6bd02a7aa740075eee9f1be3 82 Pfam PF01191 RNA polymerase Rpb5, C-terminal domain 7 79 5.2E-33 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L04_04795 d07e4e2d6bd02a7aa740075eee9f1be3 82 Gene3D G3DSA:3.90.940.20 1 82 1.9E-36 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L04_04795 d07e4e2d6bd02a7aa740075eee9f1be3 82 ProSitePatterns PS01110 RNA polymerases H / 23 Kd subunits signature. 12 25 - T 23-10-2018 IPR020608 RNA polymerase, subunit H/Rpb5, conserved site Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L04_02965 37ad2a0a03b3c1348ecc8f5be9d92a37 337 SUPERFAMILY SSF81345 5 331 4.18E-83 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L04_02965 37ad2a0a03b3c1348ecc8f5be9d92a37 337 Pfam PF01032 FecCD transport family 23 331 2.1E-89 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A3L04_02965 37ad2a0a03b3c1348ecc8f5be9d92a37 337 Gene3D G3DSA:1.10.3470.10 10 336 4.8E-99 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L04_04880 1e76e92eb905530987e3ff09b15c55f3 219 Pfam PF07302 AroM protein 3 217 1.6E-74 T 23-10-2018 IPR010843 Uncharacterised protein family AroM A3L04_04880 1e76e92eb905530987e3ff09b15c55f3 219 ProDom PD037589 AROM ARO OPERON REGULATED BY AROR BIOSYNTHESIS TRANSCRIPTION AMINO AROMATIC 2 217 3.0E-66 T 23-10-2018 IPR010843 Uncharacterised protein family AroM A3L04_01275 cb590b3c4f27a25f1bf6f78db3d4435f 215 SUPERFAMILY SSF53271 7 175 1.7E-38 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L04_01275 cb590b3c4f27a25f1bf6f78db3d4435f 215 Gene3D G3DSA:3.40.50.2020 6 183 6.5E-43 T 23-10-2018 A3L04_01275 cb590b3c4f27a25f1bf6f78db3d4435f 215 Pfam PF00156 Phosphoribosyl transferase domain 17 152 9.8E-23 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L04_05460 1e37297fd912087d33d3b38c49b6c8e0 208 Pfam PF11667 Putative zincin peptidase 54 158 4.8E-23 T 23-10-2018 IPR021683 Putative zincin peptidase A3L04_06155 996a1e9ad91e8a84724aca57c9e88201 432 Gene3D G3DSA:1.25.40.10 3 408 5.0E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L04_09830 5a99f5ead87c711ca3b76fab12027127 105 Pfam PF06677 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 10 46 2.5E-15 T 23-10-2018 IPR009563 Sjoegren syndrome/scleroderma autoantigen 1 A3L04_09830 5a99f5ead87c711ca3b76fab12027127 105 Hamap MF_00343 UPF0148 protein . 4 100 21.641 T 23-10-2018 IPR022954 Uncharacterised protein family UPF0148 A3L04_09830 5a99f5ead87c711ca3b76fab12027127 105 SMART SM00661 24 70 0.0037 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 A3L04_04630 20f364f9d848019d20e105e39416886d 278 SUPERFAMILY SSF63992 1 274 3.53E-84 T 23-10-2018 IPR036177 Peptidase M55, D-aminopeptidase superfamily A3L04_04630 20f364f9d848019d20e105e39416886d 278 PIRSF PIRSF015853 1 275 4.6E-99 T 23-10-2018 IPR007035 Peptidase M55, D-aminopeptidase A3L04_04630 20f364f9d848019d20e105e39416886d 278 Gene3D G3DSA:3.30.1360.130 118 261 4.8E-76 T 23-10-2018 A3L04_04630 20f364f9d848019d20e105e39416886d 278 Pfam PF04951 D-aminopeptidase 1 263 9.1E-82 T 23-10-2018 IPR007035 Peptidase M55, D-aminopeptidase A3L04_04630 20f364f9d848019d20e105e39416886d 278 Gene3D G3DSA:3.40.50.10780 1 215 4.8E-76 T 23-10-2018 IPR027476 D-aminopeptidase, N-terminal A3L04_03490 e48b69d910f4876791586155ce741f4f 147 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 29 145 6.8E-20 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P A3L04_03490 e48b69d910f4876791586155ce741f4f 147 Gene3D G3DSA:3.100.10.10 63 147 1.5E-23 T 23-10-2018 A3L04_03490 e48b69d910f4876791586155ce741f4f 147 SUPERFAMILY SSF52080 5 147 8.24E-34 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily A3L04_03490 e48b69d910f4876791586155ce741f4f 147 ProSitePatterns PS00475 Ribosomal protein L15 signature. 111 141 - T 23-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_03490 e48b69d910f4876791586155ce741f4f 147 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 1 147 14.031 T 23-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 A3L04_03490 e48b69d910f4876791586155ce741f4f 147 Gene3D G3DSA:4.10.990.10 4 54 5.9E-10 T 23-10-2018 IPR027386 50S ribosomal protein L15, N-terminal A3L04_01025 a9090b1b9ca0d59c73e59711c1f907b4 114 SUPERFAMILY SSF160980 1 89 4.58E-21 T 23-10-2018 A3L04_01025 a9090b1b9ca0d59c73e59711c1f907b4 114 Gene3D G3DSA:3.40.50.10640 1 94 2.4E-20 T 23-10-2018 A3L04_01025 a9090b1b9ca0d59c73e59711c1f907b4 114 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 3 96 1.0E-8 T 23-10-2018 IPR019016 CRISPR-associated DxTHG protein A3L04_09545 5d9da46dcfc0c1d9d5ad47f61b14de40 64 Gene3D G3DSA:3.40.50.1010 1 63 9.8E-8 T 23-10-2018 A3L04_09545 5d9da46dcfc0c1d9d5ad47f61b14de40 64 SUPERFAMILY SSF88723 5 59 2.52E-9 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_09545 5d9da46dcfc0c1d9d5ad47f61b14de40 64 Pfam PF01850 PIN domain 5 59 4.8E-14 T 23-10-2018 IPR002716 PIN domain A3L04_03345 0c708071a776163a9a1bd59c73c03768 67 Gene3D G3DSA:1.10.20.10 1 67 8.9E-25 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L04_03345 0c708071a776163a9a1bd59c73c03768 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 3 65 7.8E-21 T 23-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain A3L04_03345 0c708071a776163a9a1bd59c73c03768 67 SUPERFAMILY SSF47113 4 66 3.47E-20 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L04_00285 383389769837204e26adf03373818d0d 495 SUPERFAMILY SSF51905 4 415 2.85E-55 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_00285 383389769837204e26adf03373818d0d 495 Gene3D G3DSA:3.30.9.10 91 322 1.6E-113 T 23-10-2018 A3L04_00285 383389769837204e26adf03373818d0d 495 Pfam PF04324 BFD-like [2Fe-2S] binding domain 407 465 2.9E-15 T 23-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A3L04_00285 383389769837204e26adf03373818d0d 495 Pfam PF01266 FAD dependent oxidoreductase 5 361 7.9E-67 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A3L04_00285 383389769837204e26adf03373818d0d 495 Gene3D G3DSA:3.50.50.60 6 355 1.6E-113 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_00285 383389769837204e26adf03373818d0d 495 Gene3D G3DSA:1.10.10.1100 394 474 6.1E-18 T 23-10-2018 A3L04_00285 383389769837204e26adf03373818d0d 495 SUPERFAMILY SSF54373 224 319 1.23E-7 T 23-10-2018 A3L04_02265 763b4a6335268336f63559c236e65d48 101 Gene3D G3DSA:3.30.70.1340 1 86 8.5E-35 T 23-10-2018 IPR023129 MTH889-like domain superfamily A3L04_02265 763b4a6335268336f63559c236e65d48 101 ProDom PD012512 ARCHAEA PH1931 STS176 TA1183 MJ0319 PRECURSOR TVG0378908 UNCHARACTERIZED DUF211 AF1549 12 95 4.0E-39 T 23-10-2018 IPR003831 Protein of unknown function DUF211 A3L04_02265 763b4a6335268336f63559c236e65d48 101 Pfam PF02680 Uncharacterized ArCR, COG1888 5 90 1.4E-37 T 23-10-2018 IPR003831 Protein of unknown function DUF211 A3L04_02265 763b4a6335268336f63559c236e65d48 101 SUPERFAMILY SSF160363 4 93 1.2E-34 T 23-10-2018 IPR023129 MTH889-like domain superfamily A3L04_03855 f34d59861fec980aea644f79ed8ef8ec 273 Hamap MF_00370 Shikimate kinase [aroK]. 1 273 103.947 T 23-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A3L04_03855 f34d59861fec980aea644f79ed8ef8ec 273 PIRSF PIRSF005758 1 273 2.9E-96 T 23-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A3L04_03855 f34d59861fec980aea644f79ed8ef8ec 273 Pfam PF00288 GHMP kinases N terminal domain 78 146 1.2E-14 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A3L04_03855 f34d59861fec980aea644f79ed8ef8ec 273 SUPERFAMILY SSF54211 26 173 3.34E-25 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L04_03855 f34d59861fec980aea644f79ed8ef8ec 273 Gene3D G3DSA:3.30.230.10 7 160 4.6E-23 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L04_03855 f34d59861fec980aea644f79ed8ef8ec 273 TIGRFAM TIGR01920 Shik_kin_archae: shikimate kinase 7 270 4.6E-96 T 23-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A3L04_09850 12a1720508aa8fa88702d120188c8863 238 SMART SM00382 27 202 3.2E-19 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_09850 12a1720508aa8fa88702d120188c8863 238 Gene3D G3DSA:3.40.50.300 5 231 5.8E-63 T 23-10-2018 A3L04_09850 12a1720508aa8fa88702d120188c8863 238 Pfam PF00005 ABC transporter 18 155 4.2E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_09850 12a1720508aa8fa88702d120188c8863 238 SUPERFAMILY SSF52540 7 215 6.35E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09395 7204b9c18f90829148e108244f100822 137 Pfam PF01894 Uncharacterised protein family UPF0047 20 133 8.6E-36 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L04_09395 7204b9c18f90829148e108244f100822 137 Gene3D G3DSA:2.60.120.460 1 137 6.4E-50 T 23-10-2018 IPR035917 YjbQ-like superfamily A3L04_09395 7204b9c18f90829148e108244f100822 137 PIRSF PIRSF004681 1 137 2.6E-39 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L04_09395 7204b9c18f90829148e108244f100822 137 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 8 137 3.7E-35 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L04_09395 7204b9c18f90829148e108244f100822 137 SUPERFAMILY SSF111038 1 137 1.15E-44 T 23-10-2018 IPR035917 YjbQ-like superfamily A3L04_05650 3f38bad06bdb1196583c1d7372a67299 250 Pfam PF00005 ABC transporter 19 164 2.2E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_05650 3f38bad06bdb1196583c1d7372a67299 250 SUPERFAMILY SSF52540 4 214 5.65E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_05650 3f38bad06bdb1196583c1d7372a67299 250 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_05650 3f38bad06bdb1196583c1d7372a67299 250 SMART SM00382 28 211 1.9E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_05650 3f38bad06bdb1196583c1d7372a67299 250 Gene3D G3DSA:3.40.50.300 3 243 5.4E-64 T 23-10-2018 A3L04_05415 bee7568dff1f815879c7844be094b7c4 252 SUPERFAMILY SSF56300 1 249 9.49E-58 T 23-10-2018 A3L04_05415 bee7568dff1f815879c7844be094b7c4 252 Gene3D G3DSA:3.60.21.10 1 252 1.2E-54 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L04_05415 bee7568dff1f815879c7844be094b7c4 252 PIRSF PIRSF000883 2 252 8.4E-28 T 23-10-2018 IPR011152 Phosphoesterase MJ0912 A3L04_07345 0dff5065906413c19d6f98d200b30f1c 182 SUPERFAMILY SSF48371 31 142 8.64E-12 T 23-10-2018 IPR016024 Armadillo-type fold A3L04_07345 0dff5065906413c19d6f98d200b30f1c 182 Gene3D G3DSA:1.25.10.10 5 133 4.7E-7 T 23-10-2018 IPR011989 Armadillo-like helical A3L04_03275 216e86634047cdfd4144896fd103a62d 136 Gene3D G3DSA:1.20.120.330 3 131 3.0E-40 T 23-10-2018 A3L04_03275 216e86634047cdfd4144896fd103a62d 136 Pfam PF05168 HEPN domain 8 128 1.1E-37 T 23-10-2018 IPR007842 HEPN domain A3L04_03275 216e86634047cdfd4144896fd103a62d 136 SMART SM00748 11 123 9.7E-41 T 23-10-2018 IPR007842 HEPN domain A3L04_03275 216e86634047cdfd4144896fd103a62d 136 SUPERFAMILY SSF81593 5 129 4.71E-43 T 23-10-2018 A3L04_01980 000356748dafb8c8bdb0f0f0395e9f01 291 Pfam PF02355 Protein export membrane protein 108 284 3.1E-33 T 23-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A3L04_01980 000356748dafb8c8bdb0f0f0395e9f01 291 SUPERFAMILY SSF82866 100 276 1.96E-23 T 23-10-2018 A3L04_01980 000356748dafb8c8bdb0f0f0395e9f01 291 Hamap MF_01464_A Protein-export membrane protein SecF [secF]. 10 289 26.246 T 23-10-2018 IPR024921 Protein-export membrane protein SecF, archaeal GO:0016021|GO:0065002 A3L04_01980 000356748dafb8c8bdb0f0f0395e9f01 291 Gene3D G3DSA:1.20.1640.10 108 291 6.3E-11 T 23-10-2018 A3L04_01800 4dd7975c087867eab56ca42ca508e374 383 Gene3D G3DSA:3.30.420.40 149 309 1.7E-6 T 23-10-2018 A3L04_01800 4dd7975c087867eab56ca42ca508e374 383 SUPERFAMILY SSF53067 4 306 2.04E-11 T 23-10-2018 A3L04_01800 4dd7975c087867eab56ca42ca508e374 383 Pfam PF07318 Protein of unknown function (DUF1464) 6 368 8.2E-99 T 23-10-2018 IPR009927 Protein of unknown function DUF1464 A3L04_01800 4dd7975c087867eab56ca42ca508e374 383 PIRSF PIRSF009433 1 382 1.4E-148 T 23-10-2018 IPR009927 Protein of unknown function DUF1464 A3L04_04135 bda648283ff4e0f2da2a0b509df65cd5 187 Pfam PF13630 SdpI/YhfL protein family 21 83 1.8E-10 T 23-10-2018 IPR025962 SdpI/YhfL protein family A3L04_08605 5395449db8a9b7ec2332af096283a8ce 79 Pfam PF01637 ATPase domain predominantly from Archaea 2 61 1.3E-16 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_08605 5395449db8a9b7ec2332af096283a8ce 79 SUPERFAMILY SSF52540 1 63 1.05E-11 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_08605 5395449db8a9b7ec2332af096283a8ce 79 Gene3D G3DSA:3.40.50.300 1 72 4.6E-11 T 23-10-2018 A3L04_08245 6b2774a993faa22062672a0cd20e6272 473 Pfam PF01523 Putative modulator of DNA gyrase 19 325 3.8E-59 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L04_08245 6b2774a993faa22062672a0cd20e6272 473 PIRSF PIRSF004919 1 472 5.7E-153 T 23-10-2018 IPR025502 TldD A3L04_08245 6b2774a993faa22062672a0cd20e6272 473 Gene3D G3DSA:3.30.2290.10 1 196 2.2E-28 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L04_08245 6b2774a993faa22062672a0cd20e6272 473 SUPERFAMILY SSF111283 1 468 6.28E-107 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L04_01490 57cf46ba8bae05ef21599df69a999338 469 SMART SM00316 90 150 0.0027 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L04_01490 57cf46ba8bae05ef21599df69a999338 469 Pfam PF10150 Ribonuclease E/G family 150 288 1.4E-11 T 23-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 A3L04_01490 57cf46ba8bae05ef21599df69a999338 469 Hamap MF_01910 RNA-binding protein AU-1 [aubA]. 7 469 32.904 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 A3L04_01490 57cf46ba8bae05ef21599df69a999338 469 SUPERFAMILY SSF159234 316 469 4.84E-29 T 23-10-2018 IPR035930 FomD-like superfamily A3L04_01490 57cf46ba8bae05ef21599df69a999338 469 Pfam PF04167 Protein of unknown function (DUF402) 375 441 2.9E-13 T 23-10-2018 IPR007295 Domain of unknown function DUF402 A3L04_01490 57cf46ba8bae05ef21599df69a999338 469 Gene3D G3DSA:2.40.380.10 355 469 8.3E-9 T 23-10-2018 IPR035930 FomD-like superfamily A3L04_01490 57cf46ba8bae05ef21599df69a999338 469 PIRSF PIRSF018644 5 469 4.7E-197 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 A3L04_01150 1884afab8b45877232e8caec143dfbab 389 Pfam PF13173 AAA domain 46 179 1.2E-19 T 23-10-2018 A3L04_01150 1884afab8b45877232e8caec143dfbab 389 SUPERFAMILY SSF52540 42 215 9.52E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_04945 efcc40d67e872fe39d4a3ba579c41394 424 Pfam PF12698 ABC-2 family transporter protein 19 401 6.3E-34 T 23-10-2018 A3L04_04945 efcc40d67e872fe39d4a3ba579c41394 424 Gene3D G3DSA:3.40.1710.10 41 201 1.7E-35 T 23-10-2018 A3L04_03090 7f8ca99145c2f01a146221339dff986c 196 Gene3D G3DSA:1.10.1760.20 33 193 1.2E-39 T 23-10-2018 A3L04_03090 7f8ca99145c2f01a146221339dff986c 196 Pfam PF07155 ECF-type riboflavin transporter, S component 42 190 1.1E-30 T 23-10-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 A3L04_09705 2c2d1c7b350980ae713c0543251886f5 239 Gene3D G3DSA:3.30.70.1890 1 120 2.6E-50 T 23-10-2018 A3L04_09705 2c2d1c7b350980ae713c0543251886f5 239 Pfam PF01881 CRISPR associated protein Cas6 96 236 2.2E-30 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L04_09705 2c2d1c7b350980ae713c0543251886f5 239 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 47 236 5.7E-47 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L04_09705 2c2d1c7b350980ae713c0543251886f5 239 Gene3D G3DSA:3.30.70.1900 121 239 1.2E-39 T 23-10-2018 A3L04_09705 2c2d1c7b350980ae713c0543251886f5 239 PIRSF PIRSF005054 1 239 1.2E-55 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L04_02605 e1d0ca81de11aa630a5f76db5f8df744 281 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 3 264 4.3E-114 T 23-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 A3L04_02605 e1d0ca81de11aa630a5f76db5f8df744 281 SUPERFAMILY SSF53448 3 274 1.81E-66 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_02605 e1d0ca81de11aa630a5f76db5f8df744 281 Gene3D G3DSA:3.90.550.10 1 278 2.5E-88 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_02605 e1d0ca81de11aa630a5f76db5f8df744 281 Pfam PF00483 Nucleotidyl transferase 5 268 1.3E-32 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L04_09805 3b0b036c904ea8fa00f84de66ffa99fc 264 Pfam PF13649 Methyltransferase domain 43 142 1.5E-7 T 23-10-2018 A3L04_09805 3b0b036c904ea8fa00f84de66ffa99fc 264 SUPERFAMILY SSF53335 25 153 3.75E-15 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_09805 3b0b036c904ea8fa00f84de66ffa99fc 264 Gene3D G3DSA:3.40.50.150 4 158 5.2E-14 T 23-10-2018 A3L04_01955 6a66d738e77333a3cb3e56f83043ddaf 167 Pfam PF11447 Protein of unknown function (DUF3201) 8 155 6.1E-67 T 23-10-2018 IPR024505 Protein of unknown function DUF3201 A3L04_01955 6a66d738e77333a3cb3e56f83043ddaf 167 Gene3D G3DSA:3.30.930.10 1 167 4.5E-78 T 23-10-2018 A3L04_01955 6a66d738e77333a3cb3e56f83043ddaf 167 SUPERFAMILY SSF142913 2 167 7.32E-66 T 23-10-2018 A3L04_01455 fd6866061d5dbbdd8073b2f12a07b2ee 257 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 3 238 1.8E-102 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A3L04_01455 fd6866061d5dbbdd8073b2f12a07b2ee 257 Pfam PF01048 Phosphorylase superfamily 3 237 1.2E-52 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A3L04_01455 fd6866061d5dbbdd8073b2f12a07b2ee 257 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 48 88 - T 23-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 A3L04_01455 fd6866061d5dbbdd8073b2f12a07b2ee 257 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 257 45.902 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A3L04_01455 fd6866061d5dbbdd8073b2f12a07b2ee 257 Gene3D G3DSA:3.40.50.1580 1 257 1.2E-108 T 23-10-2018 A3L04_01455 fd6866061d5dbbdd8073b2f12a07b2ee 257 SUPERFAMILY SSF53167 1 255 1.15E-95 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A3L04_02845 6da5a273adf52fb37360a804ed3a72c0 120 SUPERFAMILY SSF52172 1 119 6.69E-41 T 23-10-2018 IPR011006 CheY-like superfamily A3L04_02845 6da5a273adf52fb37360a804ed3a72c0 120 Pfam PF00072 Response regulator receiver domain 4 114 1.1E-33 T 23-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A3L04_02845 6da5a273adf52fb37360a804ed3a72c0 120 Gene3D G3DSA:3.40.50.2300 1 120 6.1E-42 T 23-10-2018 A3L04_02845 6da5a273adf52fb37360a804ed3a72c0 120 SMART SM00448 2 114 2.7E-39 T 23-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A3L04_07250 96b898a2097b2c9e8cbfe677845cf767 525 ProSitePatterns PS00306 Caseins alpha/beta signature. 11 18 - T 23-10-2018 IPR031305 Casein alpha/beta, conserved site A3L04_07250 96b898a2097b2c9e8cbfe677845cf767 525 SUPERFAMILY SSF49478 244 295 3.77E-5 T 23-10-2018 A3L04_07250 96b898a2097b2c9e8cbfe677845cf767 525 Gene3D G3DSA:2.60.40.10 292 370 6.5E-5 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L04_07250 96b898a2097b2c9e8cbfe677845cf767 525 Gene3D G3DSA:2.60.40.10 26 120 5.8E-6 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L04_00140 f1f9716d801d8c407ab2888bedd08843 335 Gene3D G3DSA:3.30.360.10 125 334 4.7E-49 T 23-10-2018 A3L04_00140 f1f9716d801d8c407ab2888bedd08843 335 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 205 3.7E-4 T 23-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 A3L04_00140 f1f9716d801d8c407ab2888bedd08843 335 SUPERFAMILY SSF51735 2 151 1.25E-39 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_00140 f1f9716d801d8c407ab2888bedd08843 335 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 17 121 2.8E-22 T 23-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A3L04_00140 f1f9716d801d8c407ab2888bedd08843 335 Gene3D G3DSA:3.40.50.720 1 124 2.4E-27 T 23-10-2018 A3L04_00140 f1f9716d801d8c407ab2888bedd08843 335 SUPERFAMILY SSF55347 131 306 1.11E-31 T 23-10-2018 A3L04_08305 0dcd34b4a2c5b0aa09753e65048741bf 394 Pfam PF13173 AAA domain 48 178 7.9E-24 T 23-10-2018 A3L04_08305 0dcd34b4a2c5b0aa09753e65048741bf 394 SUPERFAMILY SSF52540 43 228 2.54E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_08305 0dcd34b4a2c5b0aa09753e65048741bf 394 Gene3D G3DSA:3.40.50.300 21 126 1.1E-6 T 23-10-2018 A3L04_02635 48b5cb8dfbca63d704ab9ee99bc6845b 67 SUPERFAMILY SSF88723 2 55 5.05E-8 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_02635 48b5cb8dfbca63d704ab9ee99bc6845b 67 Pfam PF01850 PIN domain 2 53 9.2E-11 T 23-10-2018 IPR002716 PIN domain A3L04_02635 48b5cb8dfbca63d704ab9ee99bc6845b 67 Gene3D G3DSA:3.40.50.1010 1 67 2.3E-6 T 23-10-2018 A3L04_06195 b4152f28813e7dcf6d2f349df59c86f9 267 SUPERFAMILY SSF103481 176 266 3.92E-8 T 23-10-2018 A3L04_06195 b4152f28813e7dcf6d2f349df59c86f9 267 Pfam PF00892 EamA-like transporter family 143 265 3.2E-13 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L04_06195 b4152f28813e7dcf6d2f349df59c86f9 267 Pfam PF00892 EamA-like transporter family 7 133 1.3E-19 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L04_06195 b4152f28813e7dcf6d2f349df59c86f9 267 SUPERFAMILY SSF103481 45 135 2.75E-11 T 23-10-2018 A3L04_04285 bc71ab8f387b513e30e53b2d54e7af48 276 SUPERFAMILY SSF81345 4 266 1.57E-18 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L04_04285 bc71ab8f387b513e30e53b2d54e7af48 276 Pfam PF00950 ABC 3 transport family 4 266 1.8E-27 T 23-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 A3L04_10195 ce9b393a98937eb8e0328c73e6d875ba 334 Hamap MF_01086 UPF0284 protein . 1 334 140.621 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative A3L04_10195 ce9b393a98937eb8e0328c73e6d875ba 334 Gene3D G3DSA:3.40.50.10210 1 333 6.8E-130 T 23-10-2018 A3L04_10195 ce9b393a98937eb8e0328c73e6d875ba 334 SUPERFAMILY SSF52733 18 328 2.09E-45 T 23-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 A3L04_10195 ce9b393a98937eb8e0328c73e6d875ba 334 Pfam PF02277 Phosphoribosyltransferase 100 250 1.7E-8 T 23-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 A3L04_10195 ce9b393a98937eb8e0328c73e6d875ba 334 TIGRFAM TIGR00303 TIGR00303: TIGR00303 family protein 2 323 3.5E-103 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative A3L04_09435 f91bbf937c3960b92ea9978bac1a5fff 277 SUPERFAMILY SSF56281 15 265 4.6E-40 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_09435 f91bbf937c3960b92ea9978bac1a5fff 277 Gene3D G3DSA:3.40.50.10890 128 190 2.8E-21 T 23-10-2018 A3L04_09435 f91bbf937c3960b92ea9978bac1a5fff 277 Gene3D G3DSA:3.60.15.10 49 127 2.8E-21 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L04_09855 4b0a55a05312b62961025108e876eb08 331 Gene3D G3DSA:1.10.3470.10 2 328 2.3E-98 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L04_09855 4b0a55a05312b62961025108e876eb08 331 SUPERFAMILY SSF81345 4 323 6.41E-77 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L04_09855 4b0a55a05312b62961025108e876eb08 331 Pfam PF01032 FecCD transport family 13 323 1.9E-89 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A3L04_10730 750e21d4911cecc048b0d701f856caa7 227 Hamap MF_00032 Translation initiation factor 6 [eif6]. 1 227 100.976 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L04_10730 750e21d4911cecc048b0d701f856caa7 227 SMART SM00654 4 206 2.2E-116 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L04_10730 750e21d4911cecc048b0d701f856caa7 227 SUPERFAMILY SSF55909 3 226 3.43E-77 T 23-10-2018 A3L04_10730 750e21d4911cecc048b0d701f856caa7 227 Pfam PF01912 eIF-6 family 5 206 3.1E-72 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L04_10730 750e21d4911cecc048b0d701f856caa7 227 PIRSF PIRSF006413 2 227 5.0E-83 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L04_10730 750e21d4911cecc048b0d701f856caa7 227 TIGRFAM TIGR00323 eIF-6: putative translation initiation factor eIF-6 5 226 6.0E-68 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L04_10730 750e21d4911cecc048b0d701f856caa7 227 Gene3D G3DSA:3.75.10.10 1 227 6.0E-83 T 23-10-2018 A3L04_05045 f88f3a2f6f3c8e9ed61d1a66228c4b2f 445 SUPERFAMILY SSF52096 24 188 1.02E-29 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L04_05045 f88f3a2f6f3c8e9ed61d1a66228c4b2f 445 Gene3D G3DSA:2.40.50.140 373 445 4.0E-29 T 23-10-2018 A3L04_05045 f88f3a2f6f3c8e9ed61d1a66228c4b2f 445 Pfam PF01957 NfeD-like C-terminal, partner-binding 291 437 2.0E-38 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain A3L04_05045 f88f3a2f6f3c8e9ed61d1a66228c4b2f 445 Gene3D G3DSA:3.90.226.10 18 242 1.7E-68 T 23-10-2018 A3L04_05045 f88f3a2f6f3c8e9ed61d1a66228c4b2f 445 Pfam PF00574 Clp protease 31 188 1.0E-10 T 23-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A3L04_05045 f88f3a2f6f3c8e9ed61d1a66228c4b2f 445 SUPERFAMILY SSF141322 369 436 4.84E-16 T 23-10-2018 A3L04_04920 25a44795a48653947be1e02fbc7967cb 422 SUPERFAMILY SSF89550 5 227 2.94E-14 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L04_04920 25a44795a48653947be1e02fbc7967cb 422 TIGRFAM TIGR00375 TIGR00375: TIGR00375 family protein 6 380 2.0E-125 T 23-10-2018 IPR005287 Conserved hypothetical protein CHP00375 A3L04_04920 25a44795a48653947be1e02fbc7967cb 422 Gene3D G3DSA:3.20.20.140 2 230 6.6E-14 T 23-10-2018 A3L04_00240 238332f2297ef508cc2587585c7f2c53 254 Gene3D G3DSA:3.30.540.10 1 140 2.2E-39 T 23-10-2018 A3L04_00240 238332f2297ef508cc2587585c7f2c53 254 Pfam PF00459 Inositol monophosphatase family 10 240 5.0E-36 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L04_00240 238332f2297ef508cc2587585c7f2c53 254 PRINTS PR00377 Inositol monophosphatase superfamily signature 41 61 9.6E-29 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L04_00240 238332f2297ef508cc2587585c7f2c53 254 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 9.6E-29 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L04_00240 238332f2297ef508cc2587585c7f2c53 254 PRINTS PR00377 Inositol monophosphatase superfamily signature 197 221 9.6E-29 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L04_00240 238332f2297ef508cc2587585c7f2c53 254 PRINTS PR00377 Inositol monophosphatase superfamily signature 164 185 9.6E-29 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L04_00240 238332f2297ef508cc2587585c7f2c53 254 PRINTS PR00377 Inositol monophosphatase superfamily signature 130 153 9.6E-29 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L04_00240 238332f2297ef508cc2587585c7f2c53 254 SUPERFAMILY SSF56655 5 253 2.36E-56 T 23-10-2018 A3L04_00240 238332f2297ef508cc2587585c7f2c53 254 Gene3D G3DSA:3.40.190.80 141 253 9.5E-30 T 23-10-2018 A3L04_06790 6e0177e1d698474bc832695bee62373b 364 Gene3D G3DSA:3.40.50.300 88 359 4.6E-80 T 23-10-2018 A3L04_06790 6e0177e1d698474bc832695bee62373b 364 SUPERFAMILY SSF52540 91 361 2.8E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_06790 6e0177e1d698474bc832695bee62373b 364 SMART SM00382 121 255 3.8E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_06790 6e0177e1d698474bc832695bee62373b 364 Gene3D G3DSA:1.10.8.60 254 343 4.6E-80 T 23-10-2018 A3L04_06790 6e0177e1d698474bc832695bee62373b 364 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 125 253 5.9E-39 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L04_06790 6e0177e1d698474bc832695bee62373b 364 Pfam PF09336 Vps4 C terminal oligomerisation domain 321 362 5.7E-8 T 23-10-2018 IPR015415 Vps4 oligomerisation, C-terminal A3L04_09080 9f93e6c4664c1316db8ba6a73ec4bb59 312 Pfam PF03787 RAMP superfamily 2 125 2.8E-7 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein A3L04_09080 9f93e6c4664c1316db8ba6a73ec4bb59 312 TIGRFAM TIGR01894 cas_TM1795_cmr1: CRISPR type III-B/RAMP module RAMP protein Cmr1 1 126 2.8E-26 T 23-10-2018 IPR007522 CRISPR-associated protein TM1795 A3L04_08710 ddb8816234582c3cf2e4d6b43f4f5d35 373 Pfam PF04055 Radical SAM superfamily 23 184 5.5E-15 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_08710 ddb8816234582c3cf2e4d6b43f4f5d35 373 TIGRFAM TIGR04317 W_rSAM_matur: tungsten cofactor oxidoreducase radical SAM maturase 17 363 7.3E-150 T 23-10-2018 IPR027604 Tungsten cofactor oxidoreducase radical SAM maturase A3L04_08710 ddb8816234582c3cf2e4d6b43f4f5d35 373 SUPERFAMILY SSF102114 19 333 1.01E-50 T 23-10-2018 A3L04_08710 ddb8816234582c3cf2e4d6b43f4f5d35 373 Pfam PF13186 Iron-sulfur cluster-binding domain 250 328 4.8E-13 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A3L04_08710 ddb8816234582c3cf2e4d6b43f4f5d35 373 SMART SM00729 19 228 0.005 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L04_08710 ddb8816234582c3cf2e4d6b43f4f5d35 373 Pfam PF13353 4Fe-4S single cluster domain 26 109 1.1E-5 T 23-10-2018 A3L04_03015 c689e8500903d78fec6efb1d98482604 220 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 13 211 5.6E-28 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L04_03015 c689e8500903d78fec6efb1d98482604 220 Gene3D G3DSA:3.40.50.11570 4 215 6.8E-39 T 23-10-2018 A3L04_02665 0fce368c9b29b7e0a54663d9b4d4719c 308 SUPERFAMILY SSF53448 2 296 1.22E-53 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_02665 0fce368c9b29b7e0a54663d9b4d4719c 308 Gene3D G3DSA:3.90.550.10 1 231 1.0E-52 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_02665 0fce368c9b29b7e0a54663d9b4d4719c 308 Pfam PF00535 Glycosyl transferase family 2 8 180 4.8E-28 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L04_05785 e1660dcd2461a54692a89161c92175b5 329 Gene3D G3DSA:1.10.3730.40 183 329 6.4E-57 T 23-10-2018 A3L04_05785 e1660dcd2461a54692a89161c92175b5 329 SUPERFAMILY SSF51735 3 183 9.73E-75 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_05785 e1660dcd2461a54692a89161c92175b5 329 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 328 6.1E-136 T 23-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A3L04_05785 e1660dcd2461a54692a89161c92175b5 329 PIRSF PIRSF000116 1 208 3.0E-52 T 23-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A3L04_05785 e1660dcd2461a54692a89161c92175b5 329 PIRSF PIRSF000116 202 328 2.1E-8 T 23-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A3L04_05785 e1660dcd2461a54692a89161c92175b5 329 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 324 1.6E-53 T 23-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A3L04_05785 e1660dcd2461a54692a89161c92175b5 329 Gene3D G3DSA:3.40.50.720 1 182 1.4E-83 T 23-10-2018 A3L04_05785 e1660dcd2461a54692a89161c92175b5 329 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 178 1.1E-79 T 23-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A3L04_05785 e1660dcd2461a54692a89161c92175b5 329 SUPERFAMILY SSF48179 184 325 7.14E-55 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A3L04_05785 e1660dcd2461a54692a89161c92175b5 329 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 329 41.859 T 23-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A3L04_01220 ea0fb601884b8e1d91d3e47f761e0fcc 281 SUPERFAMILY SSF51569 8 266 6.59E-70 T 23-10-2018 A3L04_01220 ea0fb601884b8e1d91d3e47f761e0fcc 281 Gene3D G3DSA:3.20.20.70 3 279 2.8E-83 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_01220 ea0fb601884b8e1d91d3e47f761e0fcc 281 Pfam PF01791 DeoC/LacD family aldolase 24 251 1.3E-35 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L04_01220 ea0fb601884b8e1d91d3e47f761e0fcc 281 PIRSF PIRSF038992 4 281 4.7E-93 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L04_01220 ea0fb601884b8e1d91d3e47f761e0fcc 281 SMART SM01133 23 251 2.4E-43 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L04_09970 9c65a46be6d9dc06d49dfce4f7eecac7 255 Pfam PF13614 AAA domain 3 178 2.4E-54 T 23-10-2018 IPR025669 AAA domain A3L04_09970 9c65a46be6d9dc06d49dfce4f7eecac7 255 SUPERFAMILY SSF52540 1 254 1.01E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09970 9c65a46be6d9dc06d49dfce4f7eecac7 255 Gene3D G3DSA:3.40.50.300 1 255 5.3E-74 T 23-10-2018 A3L04_09970 9c65a46be6d9dc06d49dfce4f7eecac7 255 PIRSF PIRSF009320 94 255 2.5E-9 T 23-10-2018 A3L04_09970 9c65a46be6d9dc06d49dfce4f7eecac7 255 PIRSF PIRSF009320 2 47 5.7E-13 T 23-10-2018 A3L04_07880 345c43a8b0e5139538f075b4700b81f7 249 SUPERFAMILY SSF55681 1 247 2.36E-72 T 23-10-2018 A3L04_07880 345c43a8b0e5139538f075b4700b81f7 249 Gene3D G3DSA:3.30.930.10 8 249 1.7E-67 T 23-10-2018 A3L04_07880 345c43a8b0e5139538f075b4700b81f7 249 Pfam PF03099 Biotin/lipoate A/B protein ligase family 48 158 1.9E-13 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A3L04_03340 eb6efbbe4604dd569b75cdc4a1cd2dc1 268 Pfam PF02649 Type I GTP cyclohydrolase folE2 7 264 4.2E-68 T 23-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 A3L04_03340 eb6efbbe4604dd569b75cdc4a1cd2dc1 268 Gene3D G3DSA:3.10.270.10 3 267 1.8E-70 T 23-10-2018 A3L04_03340 eb6efbbe4604dd569b75cdc4a1cd2dc1 268 Hamap MF_01527_A GTP cyclohydrolase FolE2 [folE2]. 4 268 27.558 T 23-10-2018 IPR022840 GTP cyclohydrolase MptA GO:0003933 KEGG: 00790+3.5.4.39|MetaCyc: PWY-6797|MetaCyc: PWY-7853 A3L04_08810 4748b96ee9d158c0e7cb84b329966d6b 360 Gene3D G3DSA:3.20.20.70 22 251 2.7E-17 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L04_08810 4748b96ee9d158c0e7cb84b329966d6b 360 Pfam PF13394 4Fe-4S single cluster domain 29 120 1.8E-7 T 23-10-2018 A3L04_08810 4748b96ee9d158c0e7cb84b329966d6b 360 SUPERFAMILY SSF102114 25 206 6.67E-23 T 23-10-2018 A3L04_08810 4748b96ee9d158c0e7cb84b329966d6b 360 Pfam PF04055 Radical SAM superfamily 31 178 4.3E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L04_03570 df6be97016cb499b7ed59ca944f6a3bf 232 SUPERFAMILY SSF56059 23 232 1.57E-50 T 23-10-2018 A3L04_03570 df6be97016cb499b7ed59ca944f6a3bf 232 Gene3D G3DSA:3.30.1490.20 39 116 8.1E-91 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L04_03570 df6be97016cb499b7ed59ca944f6a3bf 232 Gene3D G3DSA:3.30.470.20 21 230 8.1E-91 T 23-10-2018 A3L04_03570 df6be97016cb499b7ed59ca944f6a3bf 232 Pfam PF13549 ATP-grasp domain 16 232 4.5E-83 T 23-10-2018 A3L04_02950 35f040db55328674673cd8f7ad7875ae 499 Gene3D G3DSA:3.20.20.80 13 372 1.4E-114 T 23-10-2018 A3L04_02950 35f040db55328674673cd8f7ad7875ae 499 SUPERFAMILY SSF51445 34 372 2.73E-70 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L04_02950 35f040db55328674673cd8f7ad7875ae 499 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 43 345 6.5E-56 T 23-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 A3L04_02950 35f040db55328674673cd8f7ad7875ae 499 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 173 182 - T 23-10-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 A3L04_02805 9946b71fc99e58adde53db3cd333763e 313 ProSitePatterns PS01270 Band 7 protein family signature. 135 163 - T 23-10-2018 IPR018080 Band 7/stomatin-like, conserved site A3L04_02805 9946b71fc99e58adde53db3cd333763e 313 Pfam PF01145 SPFH domain / Band 7 family 26 206 2.3E-42 T 23-10-2018 IPR001107 Band 7 domain A3L04_02805 9946b71fc99e58adde53db3cd333763e 313 PRINTS PR00721 Stomatin signature 111 128 1.7E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L04_02805 9946b71fc99e58adde53db3cd333763e 313 PRINTS PR00721 Stomatin signature 155 173 1.7E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L04_02805 9946b71fc99e58adde53db3cd333763e 313 PRINTS PR00721 Stomatin signature 131 154 1.7E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L04_02805 9946b71fc99e58adde53db3cd333763e 313 PRINTS PR00721 Stomatin signature 174 195 1.7E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L04_02805 9946b71fc99e58adde53db3cd333763e 313 PRINTS PR00721 Stomatin signature 76 97 1.7E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L04_02805 9946b71fc99e58adde53db3cd333763e 313 PRINTS PR00721 Stomatin signature 29 51 1.7E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L04_02805 9946b71fc99e58adde53db3cd333763e 313 SUPERFAMILY SSF117892 53 186 1.57E-46 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily A3L04_02805 9946b71fc99e58adde53db3cd333763e 313 Gene3D G3DSA:3.30.479.30 50 181 5.3E-51 T 23-10-2018 A3L04_02805 9946b71fc99e58adde53db3cd333763e 313 SMART SM00244 22 179 2.6E-73 T 23-10-2018 IPR001107 Band 7 domain A3L04_05020 e6d650565d2ffff329ea0f7e8647be1f 418 Gene3D G3DSA:2.30.40.10 12 413 2.1E-144 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L04_05020 e6d650565d2ffff329ea0f7e8647be1f 418 Gene3D G3DSA:3.20.20.140 53 342 2.1E-144 T 23-10-2018 A3L04_05020 e6d650565d2ffff329ea0f7e8647be1f 418 SUPERFAMILY SSF51338 2 414 1.12E-30 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L04_05020 e6d650565d2ffff329ea0f7e8647be1f 418 Pfam PF01979 Amidohydrolase family 50 395 7.9E-81 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A3L04_05020 e6d650565d2ffff329ea0f7e8647be1f 418 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 8 418 43.709 T 23-10-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 A3L04_05020 e6d650565d2ffff329ea0f7e8647be1f 418 SUPERFAMILY SSF51556 52 345 1.27E-102 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L04_03890 00c405d21a1e3dfbc506fa92643d49b4 197 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 6 190 6.9E-28 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L04_03890 00c405d21a1e3dfbc506fa92643d49b4 197 Gene3D G3DSA:3.40.50.11570 1 195 2.1E-40 T 23-10-2018 A3L04_03500 e493f328c4772926c341404d38548feb 196 Gene3D G3DSA:3.40.50.300 3 189 3.5E-58 T 23-10-2018 A3L04_03500 e493f328c4772926c341404d38548feb 196 Hamap MF_00234 Adenylate kinase [adkA]. 3 189 45.774 T 23-10-2018 IPR023477 Adenylate kinase AdkA GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A3L04_03500 e493f328c4772926c341404d38548feb 196 SUPERFAMILY SSF52540 1 188 5.09E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_03500 e493f328c4772926c341404d38548feb 196 Pfam PF13207 AAA domain 8 145 1.1E-36 T 23-10-2018 A3L04_08170 68a3411c78d9d8245620f3ad66d810d7 436 Pfam PF13635 Domain of unknown function (DUF4143) 256 372 1.6E-8 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 A3L04_08170 68a3411c78d9d8245620f3ad66d810d7 436 SUPERFAMILY SSF52540 25 197 1.05E-16 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_08170 68a3411c78d9d8245620f3ad66d810d7 436 Pfam PF13173 AAA domain 31 163 1.9E-35 T 23-10-2018 A3L04_04330 8483d1b6bda7fe5b6aca08a274b941a0 195 Pfam PF05175 Methyltransferase small domain 28 191 5.3E-43 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A3L04_04330 8483d1b6bda7fe5b6aca08a274b941a0 195 SUPERFAMILY SSF53335 7 193 2.16E-40 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_04330 8483d1b6bda7fe5b6aca08a274b941a0 195 Gene3D G3DSA:3.40.50.150 5 195 6.2E-49 T 23-10-2018 A3L04_01130 8f7db8ea86c7de739efbcf5db70fddc5 232 SUPERFAMILY SSF52540 13 173 1.77E-11 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01130 8f7db8ea86c7de739efbcf5db70fddc5 232 Gene3D G3DSA:1.10.10.10 143 231 5.8E-13 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_01130 8f7db8ea86c7de739efbcf5db70fddc5 232 Pfam PF01637 ATPase domain predominantly from Archaea 2 145 9.1E-37 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_01130 8f7db8ea86c7de739efbcf5db70fddc5 232 Gene3D G3DSA:3.40.50.300 5 120 7.2E-8 T 23-10-2018 A3L04_04410 f9325565bedca53869bd7dfa64f0a755 291 Hamap MF_00055 MEMO1 family protein . 1 290 61.55 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 A3L04_04410 f9325565bedca53869bd7dfa64f0a755 291 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 3 288 3.6E-91 T 23-10-2018 A3L04_04410 f9325565bedca53869bd7dfa64f0a755 291 Gene3D G3DSA:3.40.830.10 1 291 1.0E-68 T 23-10-2018 A3L04_04410 f9325565bedca53869bd7dfa64f0a755 291 Pfam PF01875 Memo-like protein 5 288 7.9E-75 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 A3L04_07035 7355ca22f29c7084e37b57eb3052bd23 337 Pfam PF12679 ABC-2 family transporter protein 4 336 4.6E-31 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A3L04_05680 dcab9edd9376232126c27bfd0e8c8cad 430 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 282 363 2.5E-16 T 23-10-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain A3L04_05680 dcab9edd9376232126c27bfd0e8c8cad 430 Pfam PF04326 Putative DNA-binding domain 14 119 1.9E-20 T 23-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 A3L04_05680 dcab9edd9376232126c27bfd0e8c8cad 430 Gene3D G3DSA:3.30.565.60 216 365 9.1E-38 T 23-10-2018 IPR038475 RecG, C-terminal domain superfamily A3L04_05680 dcab9edd9376232126c27bfd0e8c8cad 430 Gene3D G3DSA:1.10.10.10 366 419 5.8E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_05680 dcab9edd9376232126c27bfd0e8c8cad 430 SUPERFAMILY SSF46785 371 428 1.51E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_05680 dcab9edd9376232126c27bfd0e8c8cad 430 Gene3D G3DSA:3.30.950.30 3 125 2.5E-25 T 23-10-2018 IPR038461 Schlafen, AAA domain superfamily A3L04_04045 21a9db7571b36e2dd43f5e3171d8cf73 76 SUPERFAMILY SSF54909 2 74 4.16E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L04_04045 21a9db7571b36e2dd43f5e3171d8cf73 76 Pfam PF01037 Lrp/AsnC ligand binding domain 8 73 3.6E-16 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L04_04045 21a9db7571b36e2dd43f5e3171d8cf73 76 Gene3D G3DSA:3.30.70.920 2 72 9.6E-21 T 23-10-2018 A3L04_08255 536149c57664d5cf091c39def3ba053e 413 TIGRFAM TIGR00900 2A0121: H+ Antiporter protein 8 375 2.6E-108 T 23-10-2018 IPR004751 Drug antiporter protein GO:0015307|GO:0015893 A3L04_08255 536149c57664d5cf091c39def3ba053e 413 Pfam PF07690 Major Facilitator Superfamily 12 358 7.4E-32 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L04_08255 536149c57664d5cf091c39def3ba053e 413 SUPERFAMILY SSF103473 6 399 8.63E-43 T 23-10-2018 IPR036259 MFS transporter superfamily A3L04_08255 536149c57664d5cf091c39def3ba053e 413 Gene3D G3DSA:1.20.1250.20 206 405 2.4E-14 T 23-10-2018 A3L04_08255 536149c57664d5cf091c39def3ba053e 413 Gene3D G3DSA:1.20.1250.20 5 190 2.1E-22 T 23-10-2018 A3L04_05630 810eb02c5cba7aa1f20e06178a517e5b 99 SUPERFAMILY SSF50447 22 97 2.1E-11 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L04_05630 810eb02c5cba7aa1f20e06178a517e5b 99 Gene3D G3DSA:2.40.30.10 11 99 2.0E-14 T 23-10-2018 A3L04_07185 cd00423b3d46de4d6d49802731419ec4 239 Pfam PF09874 Predicted membrane protein (DUF2101) 22 222 1.7E-66 T 23-10-2018 IPR018663 Protein of unknown function DUF2101, membrane A3L04_01340 6fcd2536306825539df05b5c7e246b76 281 SUPERFAMILY SSF57997 124 277 6.02E-6 T 23-10-2018 A3L04_01340 6fcd2536306825539df05b5c7e246b76 281 TIGRFAM TIGR03879 near_KaiC_dom: probable regulatory domain 31 103 1.7E-24 T 23-10-2018 IPR022285 Conserved hypothetical protein CHP03879, regulatory domain, putative A3L04_01340 6fcd2536306825539df05b5c7e246b76 281 Gene3D G3DSA:1.20.5.340 190 281 1.8E-6 T 23-10-2018 A3L04_01340 6fcd2536306825539df05b5c7e246b76 281 Gene3D G3DSA:1.10.10.60 57 85 6.3E-6 T 23-10-2018 A3L04_06945 bca26550077adb064ab65eb42a71b72f 247 Pfam PF00005 ABC transporter 17 167 1.4E-22 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_06945 bca26550077adb064ab65eb42a71b72f 247 Gene3D G3DSA:3.40.50.300 1 239 2.8E-55 T 23-10-2018 A3L04_06945 bca26550077adb064ab65eb42a71b72f 247 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_06945 bca26550077adb064ab65eb42a71b72f 247 SUPERFAMILY SSF52540 2 227 7.5E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_06945 bca26550077adb064ab65eb42a71b72f 247 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 239 4.7E-84 T 23-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 A3L04_06945 bca26550077adb064ab65eb42a71b72f 247 SMART SM00382 26 221 9.0E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_09810 b0028e13196606e2ac7db42ff335c076 139 Gene3D G3DSA:1.20.120.330 3 131 1.3E-35 T 23-10-2018 A3L04_09810 b0028e13196606e2ac7db42ff335c076 139 SMART SM00748 11 123 1.6E-34 T 23-10-2018 IPR007842 HEPN domain A3L04_09810 b0028e13196606e2ac7db42ff335c076 139 Pfam PF05168 HEPN domain 7 129 1.0E-30 T 23-10-2018 IPR007842 HEPN domain A3L04_09810 b0028e13196606e2ac7db42ff335c076 139 SUPERFAMILY SSF81593 5 129 5.89E-39 T 23-10-2018 A3L04_07130 775e4de2bc4baf86d157484569192807 523 SUPERFAMILY SSF161098 269 518 1.78E-50 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_07130 775e4de2bc4baf86d157484569192807 523 SUPERFAMILY SSF161098 2 245 4.49E-50 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_07130 775e4de2bc4baf86d157484569192807 523 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 364 515 5.0E-13 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L04_07130 775e4de2bc4baf86d157484569192807 523 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 66 243 1.0E-19 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L04_07130 775e4de2bc4baf86d157484569192807 523 Gene3D G3DSA:1.10.3720.10 2 254 2.6E-61 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_07130 775e4de2bc4baf86d157484569192807 523 Gene3D G3DSA:1.10.3720.10 265 521 3.8E-49 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_00260 bcb4de73ddbb1761edc063fb9ea47c64 223 SMART SM00879 3 190 4.0E-19 T 23-10-2018 IPR007109 Brix domain A3L04_00260 bcb4de73ddbb1761edc063fb9ea47c64 223 SUPERFAMILY SSF52954 1 193 2.42E-35 T 23-10-2018 A3L04_00260 bcb4de73ddbb1761edc063fb9ea47c64 223 Gene3D G3DSA:3.40.50.10480 1 187 3.8E-33 T 23-10-2018 A3L04_00260 bcb4de73ddbb1761edc063fb9ea47c64 223 Hamap MF_00699 Probable Brix domain-containing ribosomal biogenesis protein. 2 191 31.306 T 23-10-2018 IPR023548 Probable Brix domain-containing ribosomal biogenesis protein A3L04_00650 b7fef8331dcad8275e211613c3bbee8e 96 Gene3D G3DSA:1.10.10.10 3 92 3.0E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_00650 b7fef8331dcad8275e211613c3bbee8e 96 Pfam PF12840 Helix-turn-helix domain 9 63 1.0E-15 T 23-10-2018 A3L04_00650 b7fef8331dcad8275e211613c3bbee8e 96 SUPERFAMILY SSF46785 4 86 7.35E-24 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_00650 b7fef8331dcad8275e211613c3bbee8e 96 SMART SM00418 9 90 1.1E-13 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_02790 bdcbc35d1c2d73b8bfc21763058a73a4 145 TIGRFAM TIGR01881 cas_Cmr5: CRISPR type III-B/RAMP module-associated protein Cmr5 3 139 6.1E-35 T 23-10-2018 IPR010160 CRISPR-associated protein, Cmr5 A3L04_02790 bdcbc35d1c2d73b8bfc21763058a73a4 145 SUPERFAMILY SSF158568 3 138 6.93E-39 T 23-10-2018 IPR023101 AF1862-like domain superfamily A3L04_02790 bdcbc35d1c2d73b8bfc21763058a73a4 145 Gene3D G3DSA:1.10.520.30 1 145 3.2E-47 T 23-10-2018 IPR023101 AF1862-like domain superfamily A3L04_02790 bdcbc35d1c2d73b8bfc21763058a73a4 145 Pfam PF09701 CRISPR-associated protein (Cas_Cmr5) 6 136 1.2E-37 T 23-10-2018 IPR010160 CRISPR-associated protein, Cmr5 A3L04_00395 3194241dba04624f4dc055ae0ee77750 216 Hamap MF_01318_A 50S ribosomal protein L1 [rplA]. 4 215 37.253 T 23-10-2018 IPR023669 Ribosomal protein L1, archaea GO:0003723|GO:0003735|GO:0006412|GO:0015934 A3L04_00395 3194241dba04624f4dc055ae0ee77750 216 Gene3D G3DSA:3.40.50.790 59 150 3.3E-76 T 23-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich A3L04_00395 3194241dba04624f4dc055ae0ee77750 216 Pfam PF00687 Ribosomal protein L1p/L10e family 21 210 1.3E-49 T 23-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein A3L04_00395 3194241dba04624f4dc055ae0ee77750 216 PIRSF PIRSF002155 1 216 2.9E-67 T 23-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_00395 3194241dba04624f4dc055ae0ee77750 216 ProSitePatterns PS01199 Ribosomal protein L1 signature. 114 133 - T 23-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_00395 3194241dba04624f4dc055ae0ee77750 216 SUPERFAMILY SSF56808 5 214 1.31E-65 T 23-10-2018 IPR023674 Ribosomal protein L1-like A3L04_00395 3194241dba04624f4dc055ae0ee77750 216 Gene3D G3DSA:3.30.190.20 13 213 3.3E-76 T 23-10-2018 A3L04_01270 e4ea885238d1886275af2fec6bc3c20b 294 Gene3D G3DSA:3.30.930.10 1 293 9.1E-81 T 23-10-2018 A3L04_01270 e4ea885238d1886275af2fec6bc3c20b 294 Pfam PF00152 tRNA synthetases class II (D, K and N) 4 286 1.3E-39 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L04_01270 e4ea885238d1886275af2fec6bc3c20b 294 SUPERFAMILY SSF55681 8 290 9.66E-57 T 23-10-2018 A3L04_00205 d8bac6705c5a964bf3511337d77c7228 56 Pfam PF03911 Sec61beta family 11 51 8.2E-15 T 23-10-2018 IPR016482 Protein transport protein SecG/Sec61-beta/Sbh Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L04_00205 d8bac6705c5a964bf3511337d77c7228 56 Hamap MF_00751 Preprotein translocase subunit SecG [secG]. 1 51 14.307 T 23-10-2018 IPR023531 Preprotein translocase subunit SecG A3L04_04050 832783e9807a49bf705c61f4624f57c6 180 Pfam PF03692 Putative zinc- or iron-chelating domain 26 131 7.8E-18 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein A3L04_10570 0d9ecf02f2c2458e41330bf2b99b44ff 261 Pfam PF01917 Archaebacterial flagellin 4 247 4.5E-40 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 A3L04_10570 0d9ecf02f2c2458e41330bf2b99b44ff 261 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 2 25 9.6E-6 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal A3L04_05445 c8f4d0b9f78c2e3a6c958aef9fffb492 181 Pfam PF00857 Isochorismatase family 5 178 3.2E-46 T 23-10-2018 IPR000868 Isochorismatase-like GO:0003824 A3L04_05445 c8f4d0b9f78c2e3a6c958aef9fffb492 181 Gene3D G3DSA:3.40.50.850 1 179 2.4E-74 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A3L04_05445 c8f4d0b9f78c2e3a6c958aef9fffb492 181 SUPERFAMILY SSF52499 4 178 5.49E-55 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A3L04_06225 60cdb637e99c12599f7fb0be3a5284cf 90 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 32 84 4.8E-15 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A3L04_05065 375c3b7139f9ef49933c0bd8b1e5416e 588 Pfam PF11369 Protein of unknown function (DUF3160) 252 524 1.2E-8 T 23-10-2018 IPR022601 Protein of unknown function DUF3160 A3L04_05065 375c3b7139f9ef49933c0bd8b1e5416e 588 SMART SM01325 41 586 0.0012 T 23-10-2018 IPR022601 Protein of unknown function DUF3160 A3L04_10590 79bfc19af8e4c061ac51493aee39d705 108 Pfam PF07381 Winged helix DNA-binding domain (DUF1495) 9 97 5.2E-35 T 23-10-2018 IPR010863 Protein of unknown function DUF1495 A3L04_10590 79bfc19af8e4c061ac51493aee39d705 108 SUPERFAMILY SSF46785 17 107 5.13E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_04165 1bc12b3b541aeeca0fb44295e67122cc 65 TIGRFAM TIGR04140 chp_AF_0576: TIGR04140 family protein 1 65 1.0E-18 T 23-10-2018 IPR026486 Uncharacterised protein AF_0576 A3L04_00915 264d43b2c05e1d5e244420f6a8053464 276 Pfam PF05763 Protein of unknown function (DUF835) 129 262 1.2E-35 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L04_01790 bb62763dfe73caf0fd6455d4c91233f5 227 Gene3D G3DSA:3.40.50.150 1 227 6.7E-77 T 23-10-2018 A3L04_01790 bb62763dfe73caf0fd6455d4c91233f5 227 SUPERFAMILY SSF53335 6 185 3.16E-40 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_01790 bb62763dfe73caf0fd6455d4c91233f5 227 Pfam PF13649 Methyltransferase domain 42 136 1.0E-26 T 23-10-2018 A3L04_00190 8f90b703eeeeedf8d214b7ce9712b9ad 120 SUPERFAMILY SSF50249 23 90 4.17E-7 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L04_01005 0b1684fca74430fc2f112da02d785035 158 TIGRFAM TIGR01870 cas_TM1810_Csm2: CRISPR type III-A/MTUBE-associated protein Csm2 58 154 2.8E-22 T 23-10-2018 IPR010149 CRISPR-associated protein, Csm2 Type III-A A3L04_01005 0b1684fca74430fc2f112da02d785035 158 Pfam PF03750 Csm2 Type III-A 41 155 5.2E-20 T 23-10-2018 IPR010149 CRISPR-associated protein, Csm2 Type III-A A3L04_06120 1ef46fb84bfb34a198a21713d315d730 380 Pfam PF07690 Major Facilitator Superfamily 13 198 5.1E-14 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L04_06120 1ef46fb84bfb34a198a21713d315d730 380 Gene3D G3DSA:1.20.1250.20 4 195 7.8E-17 T 23-10-2018 A3L04_06120 1ef46fb84bfb34a198a21713d315d730 380 Gene3D G3DSA:1.20.1250.20 196 375 8.9E-9 T 23-10-2018 A3L04_06120 1ef46fb84bfb34a198a21713d315d730 380 SUPERFAMILY SSF103473 5 364 9.68E-28 T 23-10-2018 IPR036259 MFS transporter superfamily A3L04_01920 607660b4b7e83c6ba598173fd506ba68 421 Pfam PF01523 Putative modulator of DNA gyrase 15 299 2.5E-44 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L04_01920 607660b4b7e83c6ba598173fd506ba68 421 SUPERFAMILY SSF111283 2 414 4.45E-76 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L04_01920 607660b4b7e83c6ba598173fd506ba68 421 Gene3D G3DSA:3.30.2290.10 1 202 6.3E-16 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L04_08820 9999366b3f779bc5508ad17ca21cf3aa 443 Pfam PF00860 Permease family 19 399 9.0E-47 T 23-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A3L04_08820 9999366b3f779bc5508ad17ca21cf3aa 443 PIRSF PIRSF005353 1 440 5.9E-165 T 23-10-2018 IPR026033 Purine permease PbuG-like A3L04_05350 981a20a836902eb670debf1d5eb19297 298 Gene3D G3DSA:1.10.10.10 1 75 9.8E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_05350 981a20a836902eb670debf1d5eb19297 298 Pfam PF12802 MarR family 6 52 3.2E-7 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A3L04_05350 981a20a836902eb670debf1d5eb19297 298 SMART SM00419 11 60 0.0084 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L04_05350 981a20a836902eb670debf1d5eb19297 298 SUPERFAMILY SSF46785 3 58 2.41E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_01575 74eb3b48c648020a0954530a3cc662f6 238 Pfam PF12840 Helix-turn-helix domain 4 57 1.5E-8 T 23-10-2018 A3L04_01575 74eb3b48c648020a0954530a3cc662f6 238 SMART SM00418 4 85 4.1E-12 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_01575 74eb3b48c648020a0954530a3cc662f6 238 SUPERFAMILY SSF46785 4 155 2.73E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_01575 74eb3b48c648020a0954530a3cc662f6 238 SUPERFAMILY SSF46785 150 202 1.14E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_01575 74eb3b48c648020a0954530a3cc662f6 238 Gene3D G3DSA:1.10.10.10 163 233 9.6E-33 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_01575 74eb3b48c648020a0954530a3cc662f6 238 Gene3D G3DSA:1.10.10.10 1 76 6.8E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_07415 8b230810c11a6fcf164c4a5a1dd589a9 193 SUPERFAMILY SSF52540 4 130 6.0E-9 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_07415 8b230810c11a6fcf164c4a5a1dd589a9 193 Pfam PF00437 Type II/IV secretion system protein 7 111 1.6E-8 T 23-10-2018 IPR001482 Type II/IV secretion system protein A3L04_07415 8b230810c11a6fcf164c4a5a1dd589a9 193 Gene3D G3DSA:3.40.50.300 5 112 2.3E-14 T 23-10-2018 A3L04_01010 bd0aedc4cb7c4f79b45edd3249338713 287 Pfam PF03787 RAMP superfamily 14 237 4.3E-25 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein A3L04_01010 bd0aedc4cb7c4f79b45edd3249338713 287 TIGRFAM TIGR02582 cas7_TM1809: CRISPR type III-A/MTUBE-associated RAMP protein Csm3 114 238 5.8E-41 T 23-10-2018 IPR013412 CRISPR-associated RAMP Csm3 A3L04_01010 bd0aedc4cb7c4f79b45edd3249338713 287 TIGRFAM TIGR02582 cas7_TM1809: CRISPR type III-A/MTUBE-associated RAMP protein Csm3 7 73 2.0E-25 T 23-10-2018 IPR013412 CRISPR-associated RAMP Csm3 A3L04_09895 65b2f0f1a9abe79a6347bcc16b0bc5c2 270 SMART SM00478 106 263 5.2E-22 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A3L04_09895 65b2f0f1a9abe79a6347bcc16b0bc5c2 270 Gene3D G3DSA:1.10.340.30 96 209 2.8E-35 T 23-10-2018 A3L04_09895 65b2f0f1a9abe79a6347bcc16b0bc5c2 270 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 102 245 1.5E-11 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A3L04_09895 65b2f0f1a9abe79a6347bcc16b0bc5c2 270 SUPERFAMILY SSF48150 85 262 1.73E-31 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A3L04_09895 65b2f0f1a9abe79a6347bcc16b0bc5c2 270 Gene3D G3DSA:1.10.1670.40 75 258 2.8E-35 T 23-10-2018 A3L04_03565 42f0ba9cdfaee4ae636197ded866e431 308 Gene3D G3DSA:3.90.25.10 168 300 6.2E-110 T 23-10-2018 A3L04_03565 42f0ba9cdfaee4ae636197ded866e431 308 SUPERFAMILY SSF51735 1 305 1.24E-101 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_03565 42f0ba9cdfaee4ae636197ded866e431 308 Pfam PF16363 GDP-mannose 4,6 dehydratase 8 297 7.8E-63 T 23-10-2018 IPR016040 NAD(P)-binding domain A3L04_03565 42f0ba9cdfaee4ae636197ded866e431 308 Gene3D G3DSA:3.40.50.720 8 288 6.2E-110 T 23-10-2018 A3L04_10245 e4d7a945b09faa4dddd4ceaafb799f75 62 Gene3D G3DSA:3.30.300.20 7 61 1.3E-7 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L04_10245 e4d7a945b09faa4dddd4ceaafb799f75 62 SUPERFAMILY SSF54814 8 60 4.8E-8 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L04_08190 e14bd61a756ce3ee5417751d5a4dcb7a 433 Pfam PF03069 Acetamidase/Formamidase family 45 417 1.6E-58 T 23-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 A3L04_08190 e14bd61a756ce3ee5417751d5a4dcb7a 433 Gene3D G3DSA:2.60.120.580 201 308 8.8E-15 T 23-10-2018 A3L04_08190 e14bd61a756ce3ee5417751d5a4dcb7a 433 SUPERFAMILY SSF141130 12 416 2.35E-46 T 23-10-2018 A3L04_05920 0d4cd2d1d7955e4ee9028d877d0debc7 197 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 87 192 3.0E-41 T 23-10-2018 IPR005642 Lysine exporter LysO A3L04_05920 0d4cd2d1d7955e4ee9028d877d0debc7 197 Pfam PF03956 Lysine exporter LysO 9 190 1.1E-56 T 23-10-2018 IPR005642 Lysine exporter LysO A3L04_01225 58009f7784721a48317ada1355ab3d45 69 SUPERFAMILY SSF50182 3 68 1.94E-31 T 23-10-2018 IPR010920 LSM domain superfamily A3L04_01225 58009f7784721a48317ada1355ab3d45 69 Gene3D G3DSA:2.30.30.100 1 69 9.5E-34 T 23-10-2018 A3L04_06290 dc10cd83fb1a73fb1d7be813e4a6cbe7 82 TIGRFAM TIGR00304 TIGR00304: TIGR00304 family protein 1 75 4.4E-19 T 23-10-2018 IPR002849 Protein of unknown function DUF131 A3L04_06290 dc10cd83fb1a73fb1d7be813e4a6cbe7 82 Pfam PF01998 Protein of unknown function DUF131 32 76 6.1E-16 T 23-10-2018 IPR002849 Protein of unknown function DUF131 A3L04_08890 4d3ec5e583d238f489991406b17129f1 309 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 305 1.1E-89 T 23-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 A3L04_08890 4d3ec5e583d238f489991406b17129f1 309 SUPERFAMILY SSF51556 1 308 2.38E-70 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L04_08890 4d3ec5e583d238f489991406b17129f1 309 Gene3D G3DSA:3.20.20.140 1 308 9.7E-89 T 23-10-2018 A3L04_01425 78a3b65f38200ba93f5e3caa3d252ce0 264 Pfam PF01889 Membrane protein of unknown function DUF63 5 261 2.6E-79 T 23-10-2018 IPR002749 Protein of unknown function DUF63 A3L04_10100 686a8f751308485dbdc8d8b5f7218bcc 98 Pfam PF03551 Transcriptional regulator PadR-like family 11 81 8.1E-19 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L04_10100 686a8f751308485dbdc8d8b5f7218bcc 98 SUPERFAMILY SSF46785 2 94 1.54E-27 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_10100 686a8f751308485dbdc8d8b5f7218bcc 98 Gene3D G3DSA:1.10.10.10 1 98 5.5E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_06000 ede52310309a81dda2d73cb244b17a79 307 Pfam PF00482 Type II secretion system (T2SS), protein F 106 229 9.9E-16 T 23-10-2018 IPR018076 Type II secretion system F domain A3L04_06000 ede52310309a81dda2d73cb244b17a79 307 Gene3D G3DSA:1.20.81.30 91 211 1.2E-5 T 23-10-2018 A3L04_09960 991968ef5408ed6b4d2dc8d203ccf177 62 SUPERFAMILY SSF47598 3 46 7.41E-12 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A3L04_09960 991968ef5408ed6b4d2dc8d203ccf177 62 Gene3D G3DSA:1.10.1220.10 11 47 1.3E-8 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A3L04_09960 991968ef5408ed6b4d2dc8d203ccf177 62 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 45 1.4E-10 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A3L04_09695 ebac8d65b550df8e70bde5f55f73a1cb 174 SMART SM00471 26 138 3.2E-12 T 23-10-2018 IPR003607 HD/PDEase domain A3L04_09695 ebac8d65b550df8e70bde5f55f73a1cb 174 Gene3D G3DSA:1.10.3210.10 1 174 6.1E-63 T 23-10-2018 A3L04_09695 ebac8d65b550df8e70bde5f55f73a1cb 174 SUPERFAMILY SSF109604 2 171 2.71E-40 T 23-10-2018 A3L04_09695 ebac8d65b550df8e70bde5f55f73a1cb 174 Pfam PF13023 HD domain 10 146 1.0E-24 T 23-10-2018 IPR006674 HD domain A3L04_09050 a31b022bb166072d7149a4cb389f30db 353 TIGRFAM TIGR01898 cas_TM1791_cmr6: CRISPR type III-B/RAMP module RAMP protein Cmr6 125 348 1.4E-60 T 23-10-2018 IPR010172 CRISPR-associated protein, TM1791 A3L04_09050 a31b022bb166072d7149a4cb389f30db 353 Pfam PF03787 RAMP superfamily 125 349 1.3E-13 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein A3L04_07745 8c52966075dac4dc1c805993b77ef8cf 266 ProDom PD039347 PF1398 MJ0538 PH1392 9 258 1.0E-74 T 23-10-2018 IPR020292 Uncharacterised protein family MJ0538 A3L04_00130 22c91bd2ced994e44c662af664800be0 382 SUPERFAMILY SSF53448 3 373 8.84E-75 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_00130 22c91bd2ced994e44c662af664800be0 382 Gene3D G3DSA:3.90.550.10 1 275 6.2E-44 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_00130 22c91bd2ced994e44c662af664800be0 382 Pfam PF00535 Glycosyl transferase family 2 5 134 1.7E-9 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L04_06850 735da6c69e3fff7644faf582e3094661 460 Pfam PF01022 Bacterial regulatory protein, arsR family 240 282 9.7E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_06850 735da6c69e3fff7644faf582e3094661 460 Pfam PF01637 ATPase domain predominantly from Archaea 5 199 3.0E-24 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_06850 735da6c69e3fff7644faf582e3094661 460 SUPERFAMILY SSF46785 225 352 2.46E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_06850 735da6c69e3fff7644faf582e3094661 460 SUPERFAMILY SSF52540 4 239 6.73E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_06850 735da6c69e3fff7644faf582e3094661 460 Pfam PF03008 Archaea bacterial proteins of unknown function 307 398 8.8E-28 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L04_06850 735da6c69e3fff7644faf582e3094661 460 Gene3D G3DSA:3.40.50.300 3 165 5.2E-32 T 23-10-2018 A3L04_09440 43b54db8dd0a20f217ee9cbcc27375bb 267 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 211 4.7E-21 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A3L04_09440 43b54db8dd0a20f217ee9cbcc27375bb 267 Hamap MF_01084 Diphthine synthase [dphB]. 2 256 36.116 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 A3L04_09440 43b54db8dd0a20f217ee9cbcc27375bb 267 PIRSF PIRSF036432 2 260 9.4E-98 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 A3L04_09440 43b54db8dd0a20f217ee9cbcc27375bb 267 SUPERFAMILY SSF53790 1 258 6.41E-63 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A3L04_09440 43b54db8dd0a20f217ee9cbcc27375bb 267 TIGRFAM TIGR00522 dph5: diphthine synthase 3 256 1.1E-101 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 A3L04_09440 43b54db8dd0a20f217ee9cbcc27375bb 267 Gene3D G3DSA:3.30.950.10 115 265 3.4E-53 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 A3L04_09440 43b54db8dd0a20f217ee9cbcc27375bb 267 Gene3D G3DSA:3.40.1010.10 1 114 8.4E-40 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A3L04_08160 e37a8a7dd5c86d7d26bfb9aeab8103b1 60 SUPERFAMILY SSF144210 4 51 2.75E-22 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 A3L04_08160 e37a8a7dd5c86d7d26bfb9aeab8103b1 60 Gene3D G3DSA:2.20.28.40 1 60 7.8E-34 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 A3L04_08160 e37a8a7dd5c86d7d26bfb9aeab8103b1 60 Hamap MF_00803 Ribosome biogenesis protein Nop10 [nop10]. 3 53 21.355 T 23-10-2018 IPR023532 H/ACA ribonucleoprotein complex subunit Nop10 , archaeal-type GO:0001522|GO:0030515|GO:0042254 A3L04_08160 e37a8a7dd5c86d7d26bfb9aeab8103b1 60 Pfam PF04135 Nucleolar RNA-binding protein, Nop10p family 1 51 2.5E-28 T 23-10-2018 IPR007264 H/ACA ribonucleoprotein complex, subunit Nop10 GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 A3L04_04925 dd6efef02a6694fd6d4e955a14e376f9 126 Pfam PF09946 Predicted membrane protein (DUF2178) 11 112 6.9E-15 T 23-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane A3L04_03725 51ef57706061c0235cef804016af42b9 284 SUPERFAMILY SSF103481 37 137 2.62E-11 T 23-10-2018 A3L04_03725 51ef57706061c0235cef804016af42b9 284 Pfam PF00892 EamA-like transporter family 3 136 6.2E-21 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L04_03725 51ef57706061c0235cef804016af42b9 284 Pfam PF00892 EamA-like transporter family 148 281 6.7E-21 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L04_03725 51ef57706061c0235cef804016af42b9 284 SUPERFAMILY SSF103481 199 283 8.5E-14 T 23-10-2018 A3L04_10610 5a7f1d8556892c7260f62b61a816327d 399 Pfam PF13635 Domain of unknown function (DUF4143) 242 343 5.0E-7 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 A3L04_10610 5a7f1d8556892c7260f62b61a816327d 399 SUPERFAMILY SSF52540 6 191 4.98E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_10610 5a7f1d8556892c7260f62b61a816327d 399 Gene3D G3DSA:3.40.50.300 1 60 2.5E-6 T 23-10-2018 A3L04_10610 5a7f1d8556892c7260f62b61a816327d 399 Pfam PF13173 AAA domain 12 140 7.5E-32 T 23-10-2018 A3L04_08085 52ae040d573dfef9a8c08add625a6b88 133 Gene3D G3DSA:3.30.460.10 1 114 6.8E-9 T 23-10-2018 A3L04_08085 52ae040d573dfef9a8c08add625a6b88 133 SUPERFAMILY SSF81301 3 111 1.37E-8 T 23-10-2018 A3L04_07530 0f7707c6ca4b5bd5d18543698c39074d 391 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 61 72 - T 23-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07530 0f7707c6ca4b5bd5d18543698c39074d 391 Gene3D G3DSA:1.10.645.20 27 391 4.2E-114 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07530 0f7707c6ca4b5bd5d18543698c39074d 391 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 139 391 2.5E-71 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07530 0f7707c6ca4b5bd5d18543698c39074d 391 SUPERFAMILY SSF56762 38 391 1.44E-93 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_03550 080c4dc060ce501c3d38aeb7e85aafc6 201 Pfam PF01022 Bacterial regulatory protein, arsR family 14 60 9.3E-16 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_03550 080c4dc060ce501c3d38aeb7e85aafc6 201 Gene3D G3DSA:1.10.10.10 1 103 6.0E-31 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_03550 080c4dc060ce501c3d38aeb7e85aafc6 201 SUPERFAMILY SSF46785 1 185 4.29E-31 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_03550 080c4dc060ce501c3d38aeb7e85aafc6 201 SMART SM00418 7 87 3.7E-18 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L04_09955 e63f6fc8a11d19e676b918194d59898e 143 Pfam PF08617 Kinase binding protein CGI-121 48 106 1.1E-5 T 23-10-2018 IPR013926 CGI121/TPRKB Reactome: R-HSA-6782315 A3L04_09955 e63f6fc8a11d19e676b918194d59898e 143 Gene3D G3DSA:3.30.2380.10 12 143 1.4E-41 T 23-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 A3L04_09955 e63f6fc8a11d19e676b918194d59898e 143 SUPERFAMILY SSF143870 8 135 1.57E-20 T 23-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 A3L04_02000 835651d28528aeb0868632c4a705094d 662 Gene3D G3DSA:3.30.70.2170 7 311 1.2E-24 T 23-10-2018 A3L04_02000 835651d28528aeb0868632c4a705094d 662 Gene3D G3DSA:1.20.1460.20 47 290 1.2E-24 T 23-10-2018 A3L04_02000 835651d28528aeb0868632c4a705094d 662 Gene3D G3DSA:3.30.70.2750 149 224 1.2E-24 T 23-10-2018 A3L04_02000 835651d28528aeb0868632c4a705094d 662 Pfam PF01496 V-type ATPase 116kDa subunit family 552 647 8.6E-13 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L04_02000 835651d28528aeb0868632c4a705094d 662 Pfam PF01496 V-type ATPase 116kDa subunit family 198 434 1.2E-18 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L04_00080 b72ecf0a37e765a8d98dfb8891d7ffc8 223 Pfam PF01061 ABC-2 type transporter 25 188 1.4E-32 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A3L04_00080 b72ecf0a37e765a8d98dfb8891d7ffc8 223 PRINTS PR00164 ABC-2 type transport system membrane protein signature 109 133 1.5E-6 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L04_00080 b72ecf0a37e765a8d98dfb8891d7ffc8 223 PRINTS PR00164 ABC-2 type transport system membrane protein signature 166 185 1.5E-6 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L04_00080 b72ecf0a37e765a8d98dfb8891d7ffc8 223 PRINTS PR00164 ABC-2 type transport system membrane protein signature 146 165 1.5E-6 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L04_00080 b72ecf0a37e765a8d98dfb8891d7ffc8 223 PIRSF PIRSF006648 5 223 2.2E-26 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L04_10740 6aec53cefaa95330c25da0dd41659b76 146 SUPERFAMILY SSF46579 6 139 4.32E-31 T 23-10-2018 A3L04_10740 6aec53cefaa95330c25da0dd41659b76 146 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 2 137 16.366 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 A3L04_10740 6aec53cefaa95330c25da0dd41659b76 146 Gene3D G3DSA:1.10.287.370 1 146 7.0E-50 T 23-10-2018 IPR009053 Prefoldin A3L04_10740 6aec53cefaa95330c25da0dd41659b76 146 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 7 137 2.5E-38 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 A3L04_10740 6aec53cefaa95330c25da0dd41659b76 146 Pfam PF02996 Prefoldin subunit 17 137 4.5E-27 T 23-10-2018 IPR004127 Prefoldin alpha-like A3L04_04175 9f546764b730aaa3baaa4410e3e1d277 259 SUPERFAMILY SSF116726 146 227 1.44E-13 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L04_04175 9f546764b730aaa3baaa4410e3e1d277 259 Pfam PF02080 TrkA-C domain 156 227 6.1E-14 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A3L04_04175 9f546764b730aaa3baaa4410e3e1d277 259 Gene3D G3DSA:3.30.70.1450 140 231 2.5E-15 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L04_06170 9779ae0d3c1a819499af7f2e848e6ba1 89 Gene3D G3DSA:3.10.20.30 1 89 9.5E-31 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L04_06170 9779ae0d3c1a819499af7f2e848e6ba1 89 SUPERFAMILY SSF54285 1 87 1.87E-24 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L04_06170 9779ae0d3c1a819499af7f2e848e6ba1 89 Pfam PF02597 ThiS family 5 89 1.0E-22 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L04_06170 9779ae0d3c1a819499af7f2e848e6ba1 89 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 3 89 3.6E-30 T 23-10-2018 IPR010038 MoaD, archaeal-type A3L04_04715 84c55b7f23976b9766af4d99cebe012d 141 Gene3D G3DSA:1.10.10.60 84 128 1.8E-5 T 23-10-2018 A3L04_04715 84c55b7f23976b9766af4d99cebe012d 141 SUPERFAMILY SSF46689 85 125 3.07E-7 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A3L04_07325 47de2c09813c271100e35244456e8b02 153 Pfam PF10050 Predicted metal-binding protein (DUF2284) 8 137 7.3E-35 T 23-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding A3L04_07325 47de2c09813c271100e35244456e8b02 153 PIRSF PIRSF018748 1 153 6.0E-58 T 23-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding A3L04_06370 1e8329a93738593b21958db5a594bcbd 162 SMART SM00966 92 134 1.4E-4 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L04_06370 1e8329a93738593b21958db5a594bcbd 162 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 93 123 8.1E-10 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L04_06370 1e8329a93738593b21958db5a594bcbd 162 Gene3D G3DSA:2.10.260.10 39 130 3.1E-30 T 23-10-2018 A3L04_06370 1e8329a93738593b21958db5a594bcbd 162 SUPERFAMILY SSF89447 90 123 2.09E-7 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L04_06370 1e8329a93738593b21958db5a594bcbd 162 PIRSF PIRSF019240 32 162 3.1E-31 T 23-10-2018 IPR016752 Uncharacterised conserved protein UCP019240, SpoVT/AbrB-related A3L04_08140 4b398890dae8bbd7dc6955bfcb2c4b5e 677 Pfam PF13360 PQQ-like domain 72 166 8.6E-7 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A3L04_08140 4b398890dae8bbd7dc6955bfcb2c4b5e 677 SUPERFAMILY SSF82171 127 602 1.1E-18 T 23-10-2018 A3L04_08140 4b398890dae8bbd7dc6955bfcb2c4b5e 677 Gene3D G3DSA:2.130.10.10 56 305 3.9E-14 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A3L04_07280 c7850c7a4c067f8d2d5738489b945f68 121 Gene3D G3DSA:2.40.10.10 4 104 1.6E-8 T 23-10-2018 A3L04_07280 c7850c7a4c067f8d2d5738489b945f68 121 SUPERFAMILY SSF50494 7 104 2.19E-8 T 23-10-2018 IPR009003 Peptidase S1, PA clan A3L04_06220 b4730917b93802a72215060b6d15b131 201 Pfam PF01899 Na+/H+ ion antiporter subunit 40 199 3.0E-38 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L04_06220 b4730917b93802a72215060b6d15b131 201 PIRSF PIRSF019239 29 201 1.7E-44 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L04_03190 cf75e9bdd4585c6a591c101adb77f9b0 493 Pfam PF02386 Cation transport protein 56 480 7.7E-72 T 23-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 A3L04_03190 cf75e9bdd4585c6a591c101adb77f9b0 493 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 96 470 1.1E-120 T 23-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 A3L04_03790 f1b4114ff930894aa32ffac2c8ef2c2f 55 TIGRFAM TIGR01206 lysW: lysine biosynthesis protein LysW 3 55 1.1E-31 T 23-10-2018 IPR005906 Lysine biosynthesis protein LysW A3L04_03790 f1b4114ff930894aa32ffac2c8ef2c2f 55 Gene3D G3DSA:2.20.28.160 3 55 2.6E-25 T 23-10-2018 A3L04_00255 66eb83c4135f7a066e0c766f4106b9ff 82 Pfam PF09341 Transcription factor Pcc1 10 80 2.8E-11 T 23-10-2018 IPR015419 CTAG/Pcc1 family A3L04_00255 66eb83c4135f7a066e0c766f4106b9ff 82 Gene3D G3DSA:3.30.310.50 1 82 4.1E-28 T 23-10-2018 A3L04_02650 75b9f86543f5db95c2e74013a3822516 240 Gene3D G3DSA:3.90.550.10 1 235 6.0E-55 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_02650 75b9f86543f5db95c2e74013a3822516 240 Pfam PF00535 Glycosyl transferase family 2 4 169 3.8E-32 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L04_02650 75b9f86543f5db95c2e74013a3822516 240 SUPERFAMILY SSF53448 1 226 9.52E-46 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_05595 50054528b6daf1b291de183e69d66030 266 Gene3D G3DSA:3.20.20.370 1 255 4.0E-116 T 23-10-2018 A3L04_05595 50054528b6daf1b291de183e69d66030 266 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 245 48.865 T 23-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A3L04_05595 50054528b6daf1b291de183e69d66030 266 Pfam PF03746 LamB/YcsF family 3 241 1.7E-109 T 23-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A3L04_05595 50054528b6daf1b291de183e69d66030 266 SUPERFAMILY SSF88713 1 253 1.86E-108 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L04_09510 4770051d5b25a028ddd4f377538e41f4 74 SUPERFAMILY SSF88723 10 54 1.67E-5 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_09510 4770051d5b25a028ddd4f377538e41f4 74 Gene3D G3DSA:3.40.50.1010 4 71 4.4E-10 T 23-10-2018 A3L04_05480 6068a9481bcf891da64bdb8b59466df2 291 Gene3D G3DSA:3.10.28.20 210 290 3.2E-35 T 23-10-2018 A3L04_05480 6068a9481bcf891da64bdb8b59466df2 291 Pfam PF03069 Acetamidase/Formamidase family 13 142 5.6E-18 T 23-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 A3L04_05480 6068a9481bcf891da64bdb8b59466df2 291 Pfam PF03069 Acetamidase/Formamidase family 143 286 6.7E-21 T 23-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 A3L04_05480 6068a9481bcf891da64bdb8b59466df2 291 Gene3D G3DSA:2.60.120.580 1 110 3.5E-29 T 23-10-2018 A3L04_05480 6068a9481bcf891da64bdb8b59466df2 291 Gene3D G3DSA:2.60.120.580 111 209 1.3E-33 T 23-10-2018 A3L04_05480 6068a9481bcf891da64bdb8b59466df2 291 SUPERFAMILY SSF141130 2 287 1.44E-87 T 23-10-2018 A3L04_01015 638c399495acce8155b93afd381c48a9 277 TIGRFAM TIGR01903 cas5_csm4: CRISPR type III-A/MTUBE-associated RAMP protein Csm4 4 265 1.1E-63 T 23-10-2018 IPR005510 CRISPR type III-associated RAMP protein Csm4 A3L04_01015 638c399495acce8155b93afd381c48a9 277 Pfam PF03787 RAMP superfamily 13 181 1.6E-4 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein A3L04_02615 8ed030e500be64d73f3f0a7926b2cf89 365 SUPERFAMILY SSF53756 24 337 2.67E-47 T 23-10-2018 A3L04_02615 8ed030e500be64d73f3f0a7926b2cf89 365 Gene3D G3DSA:3.40.50.2000 171 336 2.5E-39 T 23-10-2018 A3L04_02615 8ed030e500be64d73f3f0a7926b2cf89 365 Pfam PF00534 Glycosyl transferases group 1 186 336 1.7E-26 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L04_02615 8ed030e500be64d73f3f0a7926b2cf89 365 Gene3D G3DSA:3.40.50.2000 24 170 2.5E-39 T 23-10-2018 A3L04_05735 5aab2319f0f2d8e0cb2a6a8fbc1cc526 569 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 402 520 2.5E-31 T 23-10-2018 IPR025299 CstA, C-terminal domain A3L04_05735 5aab2319f0f2d8e0cb2a6a8fbc1cc526 569 Pfam PF02554 Carbon starvation protein CstA 1 361 1.2E-110 T 23-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 A3L04_10175 e0060a8f75299b95d0d44c391d5a5927 152 Pfam PF11848 Domain of unknown function (DUF3368) 102 145 1.2E-13 T 23-10-2018 IPR021799 Protein of unknown function DUF3368 A3L04_05730 19cd2e7f56ca39c7d7141bb256eda4ed 230 Hamap MF_02131 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase [mptE]. 7 222 35.654 T 23-10-2018 IPR027510 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, MptE GO:0003848|GO:0005524 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A3L04_05730 19cd2e7f56ca39c7d7141bb256eda4ed 230 SUPERFAMILY SSF63999 54 111 1.83E-8 T 23-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A3L04_05730 19cd2e7f56ca39c7d7141bb256eda4ed 230 Pfam PF01973 Protein of unknown function DUF115 40 183 1.7E-27 T 23-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like A3L04_00585 02509af1e9f1cfd2528105ab5df79553 239 Pfam PF01925 Sulfite exporter TauE/SafE 5 237 1.3E-57 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A3L04_04510 e5c8a44391511a3e25a53d1d0f9b1706 99 Pfam PF09876 Predicted metal-binding protein (DUF2103) 5 92 4.0E-21 T 23-10-2018 IPR018664 Protein of unknown function DUF2103, metal-binding A3L04_10680 76ea7ec67664ecf8fe86d4b445b252e1 128 Pfam PF05168 HEPN domain 3 102 6.6E-24 T 23-10-2018 IPR007842 HEPN domain A3L04_10680 76ea7ec67664ecf8fe86d4b445b252e1 128 SMART SM00748 1 98 3.1E-21 T 23-10-2018 IPR007842 HEPN domain A3L04_10680 76ea7ec67664ecf8fe86d4b445b252e1 128 SUPERFAMILY SSF81593 4 103 2.51E-23 T 23-10-2018 A3L04_10680 76ea7ec67664ecf8fe86d4b445b252e1 128 Gene3D G3DSA:1.20.120.330 1 106 3.6E-22 T 23-10-2018 A3L04_09110 a292c09434a0d1b232473b6d9e3f6146 289 Hamap MF_00188 Protease HtpX [htpX]. 6 281 31.02 T 23-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 A3L04_09110 a292c09434a0d1b232473b6d9e3f6146 289 Pfam PF01435 Peptidase family M48 67 281 5.2E-40 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A3L04_09110 a292c09434a0d1b232473b6d9e3f6146 289 Gene3D G3DSA:3.30.2010.10 61 150 4.4E-34 T 23-10-2018 A3L04_05090 8edf161f3b3581afd689e496eea6f41a 230 Gene3D G3DSA:3.40.50.720 2 230 5.1E-62 T 23-10-2018 A3L04_05090 8edf161f3b3581afd689e496eea6f41a 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 4.7E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_05090 8edf161f3b3581afd689e496eea6f41a 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.7E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_05090 8edf161f3b3581afd689e496eea6f41a 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 4.7E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_05090 8edf161f3b3581afd689e496eea6f41a 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 4.7E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_05090 8edf161f3b3581afd689e496eea6f41a 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 4.7E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_05090 8edf161f3b3581afd689e496eea6f41a 230 Pfam PF00106 short chain dehydrogenase 3 183 1.4E-40 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L04_05090 8edf161f3b3581afd689e496eea6f41a 230 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A3L04_05090 8edf161f3b3581afd689e496eea6f41a 230 SUPERFAMILY SSF51735 3 212 1.65E-53 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L04_10200 1bba231ccc395898fa1b7a15081923cc 193 Pfam PF01955 Adenosylcobinamide amidohydrolase 10 182 8.4E-46 T 23-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ A3L04_09170 e51af1cd7970e8c3a44fa4a2c79f2e75 180 SMART SM00344 24 133 2.5E-6 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L04_09170 e51af1cd7970e8c3a44fa4a2c79f2e75 180 SUPERFAMILY SSF46785 16 72 4.57E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_09170 e51af1cd7970e8c3a44fa4a2c79f2e75 180 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 40 1.1E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_09170 e51af1cd7970e8c3a44fa4a2c79f2e75 180 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 40 51 1.1E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_09170 e51af1cd7970e8c3a44fa4a2c79f2e75 180 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 51 70 1.1E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_09170 e51af1cd7970e8c3a44fa4a2c79f2e75 180 Gene3D G3DSA:1.10.10.10 23 71 3.6E-15 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_09170 e51af1cd7970e8c3a44fa4a2c79f2e75 180 Pfam PF13412 Winged helix-turn-helix DNA-binding 24 70 5.2E-15 T 23-10-2018 A3L04_10465 c5186baac82e88cb52c953223ba03d23 97 SUPERFAMILY SSF47598 15 56 1.93E-5 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A3L04_03035 865dfa95e813742748b564ff8baf9579 255 Pfam PF01061 ABC-2 type transporter 32 210 6.5E-15 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A3L04_03035 865dfa95e813742748b564ff8baf9579 255 PIRSF PIRSF006648 1 245 2.0E-16 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L04_03035 865dfa95e813742748b564ff8baf9579 255 PRINTS PR00164 ABC-2 type transport system membrane protein signature 168 187 7.2E-14 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L04_03035 865dfa95e813742748b564ff8baf9579 255 PRINTS PR00164 ABC-2 type transport system membrane protein signature 188 207 7.2E-14 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L04_03035 865dfa95e813742748b564ff8baf9579 255 PRINTS PR00164 ABC-2 type transport system membrane protein signature 131 155 7.2E-14 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L04_03035 865dfa95e813742748b564ff8baf9579 255 PRINTS PR00164 ABC-2 type transport system membrane protein signature 48 70 7.2E-14 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L04_02765 dd3adfae43a6b7910a27a0713df778c1 957 Gene3D G3DSA:3.30.70.2220 142 434 2.3E-78 T 23-10-2018 IPR038242 Cmr2, N-terminal domain superfamily A3L04_02765 dd3adfae43a6b7910a27a0713df778c1 957 TIGRFAM TIGR02577 cas_TM1794_Cmr2: CRISPR-associated protein Cas10/Cmr2, subtype III-B 344 753 1.7E-55 T 23-10-2018 IPR013407 CRISPR-associated protein Cmr2 A3L04_02765 dd3adfae43a6b7910a27a0713df778c1 957 TIGRFAM TIGR02577 cas_TM1794_Cmr2: CRISPR-associated protein Cas10/Cmr2, subtype III-B 170 286 4.0E-29 T 23-10-2018 IPR013407 CRISPR-associated protein Cmr2 A3L04_02765 dd3adfae43a6b7910a27a0713df778c1 957 Pfam PF12469 CRISPR-associated protein 171 280 1.9E-27 T 23-10-2018 IPR024615 CRISPR-associated protein Cmr2, N-terminal A3L04_02765 dd3adfae43a6b7910a27a0713df778c1 957 Gene3D G3DSA:3.30.70.2230 606 775 1.2E-35 T 23-10-2018 A3L04_05180 330dc8c41c4d3afb2745e81405dfd165 605 Gene3D G3DSA:3.10.105.10 286 507 1.5E-51 T 23-10-2018 A3L04_05180 330dc8c41c4d3afb2745e81405dfd165 605 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 583 602 1.9E-5 T 23-10-2018 IPR027552 CGP-CTERM domain A3L04_05180 330dc8c41c4d3afb2745e81405dfd165 605 SUPERFAMILY SSF53850 37 534 7.6E-106 T 23-10-2018 A3L04_05180 330dc8c41c4d3afb2745e81405dfd165 605 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 74 458 2.2E-70 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain A3L04_05180 330dc8c41c4d3afb2745e81405dfd165 605 Gene3D G3DSA:3.40.190.10 32 274 9.6E-58 T 23-10-2018 A3L04_09610 961c89dfa10bbd3cf687ed4d8fc5528c 396 Pfam PF01882 Protein of unknown function DUF58 185 268 2.2E-22 T 23-10-2018 IPR002881 Domain of unknown function DUF58 A3L04_02695 49da907de1a30e02ff51d7486337f944 354 Pfam PF13439 Glycosyltransferase Family 4 15 172 9.1E-21 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L04_02695 49da907de1a30e02ff51d7486337f944 354 Gene3D G3DSA:3.40.50.2000 180 331 9.3E-40 T 23-10-2018 A3L04_02695 49da907de1a30e02ff51d7486337f944 354 SUPERFAMILY SSF53756 2 337 7.54E-65 T 23-10-2018 A3L04_02695 49da907de1a30e02ff51d7486337f944 354 Pfam PF00534 Glycosyl transferases group 1 186 335 3.9E-31 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L04_02695 49da907de1a30e02ff51d7486337f944 354 Gene3D G3DSA:3.40.50.2000 1 179 3.0E-26 T 23-10-2018 A3L04_10055 7cd87ae29826c326e647937451116bb0 200 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 1 194 2.7E-54 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A3L04_10055 7cd87ae29826c326e647937451116bb0 200 Pfam PF01914 MarC family integral membrane protein 5 198 1.7E-54 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A3L04_04650 45093c9c44d52a52d1536e84861bcef1 255 Gene3D G3DSA:3.40.1190.20 1 253 3.1E-55 T 23-10-2018 IPR029056 Ribokinase-like A3L04_04650 45093c9c44d52a52d1536e84861bcef1 255 Pfam PF00294 pfkB family carbohydrate kinase 153 218 1.7E-7 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A3L04_04650 45093c9c44d52a52d1536e84861bcef1 255 SUPERFAMILY SSF53613 1 231 2.1E-26 T 23-10-2018 IPR029056 Ribokinase-like A3L04_06910 92fc524498c5cd4a387ec8f90b9e59e3 172 Pfam PF03773 Predicted permease 41 168 8.2E-13 T 23-10-2018 IPR005524 Predicted permease DUF318 A3L04_07110 7fa971edb4caaf3ff550dd17678f626e 62 Gene3D G3DSA:3.40.50.300 1 58 5.6E-8 T 23-10-2018 A3L04_07110 7fa971edb4caaf3ff550dd17678f626e 62 Pfam PF13175 AAA ATPase domain 1 42 4.6E-10 T 23-10-2018 A3L04_06800 d54983fc0ef6a5fc5a1edb85a91fefb1 165 Gene3D G3DSA:2.40.50.100 98 164 3.5E-30 T 23-10-2018 A3L04_06800 d54983fc0ef6a5fc5a1edb85a91fefb1 165 Pfam PF09891 Uncharacterized protein conserved in archaea (DUF2118) 3 164 5.3E-48 T 23-10-2018 IPR019217 Protein of unknown function DUF2118 A3L04_06800 d54983fc0ef6a5fc5a1edb85a91fefb1 165 PIRSF PIRSF019115 1 165 2.1E-68 T 23-10-2018 IPR019217 Protein of unknown function DUF2118 A3L04_06580 11c66b1496fe75488ade397d92cf62c3 224 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 8 200 4.2E-55 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L04_06580 11c66b1496fe75488ade397d92cf62c3 224 Gene3D G3DSA:3.40.50.11570 6 212 1.8E-49 T 23-10-2018 A3L04_08730 9a1c5eb98426fa397fb6f77ce8c9125d 162 Gene3D G3DSA:3.30.70.920 59 162 1.2E-48 T 23-10-2018 A3L04_08730 9a1c5eb98426fa397fb6f77ce8c9125d 162 Gene3D G3DSA:1.10.10.10 1 58 4.2E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_08730 9a1c5eb98426fa397fb6f77ce8c9125d 162 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 52 7.2E-15 T 23-10-2018 A3L04_08730 9a1c5eb98426fa397fb6f77ce8c9125d 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 8.2E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_08730 9a1c5eb98426fa397fb6f77ce8c9125d 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 8.2E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_08730 9a1c5eb98426fa397fb6f77ce8c9125d 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 8.2E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L04_08730 9a1c5eb98426fa397fb6f77ce8c9125d 162 SMART SM00344 6 118 1.7E-11 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L04_08730 9a1c5eb98426fa397fb6f77ce8c9125d 162 SUPERFAMILY SSF46785 5 60 2.31E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_08900 8cbb2be861d4abd96ad66d30d20aa71f 339 Pfam PF05763 Protein of unknown function (DUF835) 218 335 1.1E-29 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L04_04150 7794f64bcabcc49c1d217dea2982c649 462 Pfam PF03901 Alg9-like mannosyltransferase family 250 358 2.1E-6 T 23-10-2018 IPR005599 GPI mannosyltransferase GO:0016757 A3L04_04150 7794f64bcabcc49c1d217dea2982c649 462 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 57 218 7.1E-15 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A3L04_04500 978531986fb4a4ae11ed4bb61db31643 264 SUPERFAMILY SSF52402 21 210 1.94E-33 T 23-10-2018 A3L04_04500 978531986fb4a4ae11ed4bb61db31643 264 Gene3D G3DSA:3.40.50.620 19 218 3.9E-32 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L04_04500 978531986fb4a4ae11ed4bb61db31643 264 PIRSF PIRSF036670 1 262 1.6E-136 T 23-10-2018 IPR012122 ATPase, PP-loop, MJ1016-related A3L04_04500 978531986fb4a4ae11ed4bb61db31643 264 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 21 174 1.1E-8 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 A3L04_03600 487dd31740aa41f41dfd58ac0c227d7c 146 SUPERFAMILY SSF46785 59 134 2.25E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_03600 487dd31740aa41f41dfd58ac0c227d7c 146 Gene3D G3DSA:1.10.10.10 55 136 3.5E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_02510 02cdde0f8d5916ac16019a527e1f62ec 491 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 419 441 3.7E-10 T 23-10-2018 A3L04_02510 02cdde0f8d5916ac16019a527e1f62ec 491 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 3.7E-10 T 23-10-2018 A3L04_02510 02cdde0f8d5916ac16019a527e1f62ec 491 SUPERFAMILY SSF51905 9 461 1.3E-32 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_02510 02cdde0f8d5916ac16019a527e1f62ec 491 Gene3D G3DSA:3.50.50.60 384 462 5.4E-6 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_02510 02cdde0f8d5916ac16019a527e1f62ec 491 PIRSF PIRSF038984 2 91 1.6E-10 T 23-10-2018 IPR028348 FAD dependent protein A3L04_02510 02cdde0f8d5916ac16019a527e1f62ec 491 PIRSF PIRSF038984 137 466 7.8E-25 T 23-10-2018 IPR028348 FAD dependent protein A3L04_02510 02cdde0f8d5916ac16019a527e1f62ec 491 Pfam PF01946 Thi4 family 5 42 1.8E-8 T 23-10-2018 A3L04_02510 02cdde0f8d5916ac16019a527e1f62ec 491 Gene3D G3DSA:3.50.50.60 2 122 2.2E-20 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_02510 02cdde0f8d5916ac16019a527e1f62ec 491 Gene3D G3DSA:3.50.50.60 138 236 2.9E-5 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_01610 d90541cc6d50e15fe85319c604ca05c5 251 Gene3D G3DSA:3.40.50.300 12 251 1.7E-40 T 23-10-2018 A3L04_01610 d90541cc6d50e15fe85319c604ca05c5 251 SUPERFAMILY SSF52540 13 251 1.53E-25 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01610 d90541cc6d50e15fe85319c604ca05c5 251 Pfam PF06745 KaiC 16 250 1.2E-33 T 23-10-2018 IPR014774 KaiC-like domain A3L04_06240 7bc0b5c63036a21ffbf8f557ec56d70d 127 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 6 114 5.4E-20 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A3L04_05625 9600995fcb84a11fd129b61e2fe98a16 484 PIRSF PIRSF018875 2 483 2.1E-130 T 23-10-2018 IPR018646 Membrane protein of 12 TMs A3L04_05625 9600995fcb84a11fd129b61e2fe98a16 484 Pfam PF09847 Membrane protein of 12 TMs 40 481 8.8E-82 T 23-10-2018 IPR018646 Membrane protein of 12 TMs A3L04_04885 db3d7f1006ea3d35e8eb7e6ec44966b2 316 SUPERFAMILY SSF144052 5 314 9.55E-70 T 23-10-2018 A3L04_04885 db3d7f1006ea3d35e8eb7e6ec44966b2 316 Pfam PF02073 Thermophilic metalloprotease (M29) 119 282 1.3E-11 T 23-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A3L04_04830 9ce6e7227e5a55b005c46a4810375f54 215 Hamap MF_00480_A 30S ribosomal protein S7 [rpsG]. 15 215 38.823 T 23-10-2018 IPR026018 Ribosomal protein S7, archaeal A3L04_04830 9ce6e7227e5a55b005c46a4810375f54 215 SUPERFAMILY SSF47973 16 215 1.03E-64 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily A3L04_04830 9ce6e7227e5a55b005c46a4810375f54 215 Gene3D G3DSA:1.10.455.10 15 215 1.2E-82 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily A3L04_04830 9ce6e7227e5a55b005c46a4810375f54 215 TIGRFAM TIGR01028 uS7_euk_arch: ribosomal protein uS7 14 215 2.0E-95 T 23-10-2018 IPR005716 Ribosomal protein S5/S7, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_04830 9ce6e7227e5a55b005c46a4810375f54 215 Pfam PF00177 Ribosomal protein S7p/S5e 58 215 3.1E-40 T 23-10-2018 IPR023798 Ribosomal protein S7 domain A3L04_04830 9ce6e7227e5a55b005c46a4810375f54 215 PIRSF PIRSF002122 1 215 5.7E-55 T 23-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 A3L04_08020 0fa4ca1565c232b01d90202e779d7a0a 566 Pfam PF00361 Proton-conducting membrane transporter 90 367 8.4E-39 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_09025 c033e479512518047a62d1a3d0c1af6b 169 Pfam PF01930 Domain of unknown function DUF83 13 168 6.9E-53 T 23-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 A3L04_09025 c033e479512518047a62d1a3d0c1af6b 169 Gene3D G3DSA:3.90.320.10 11 168 1.6E-7 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal A3L04_09025 c033e479512518047a62d1a3d0c1af6b 169 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 12 168 8.6E-23 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 A3L04_05705 ca61457e1e25ec5694abc9d42413d1ee 129 Gene3D G3DSA:2.30.130.90 15 128 1.9E-11 T 23-10-2018 A3L04_05705 ca61457e1e25ec5694abc9d42413d1ee 129 PIRSF PIRSF016792 1 129 8.7E-73 T 23-10-2018 IPR014484 Uncharacterised conserved protein UCP016792 A3L04_05705 ca61457e1e25ec5694abc9d42413d1ee 129 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 79 126 7.4E-14 T 23-10-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain A3L04_09075 82dc802cef612b183e5aae1a429de73d 1061 Gene3D G3DSA:3.30.70.2220 235 452 4.0E-51 T 23-10-2018 IPR038242 Cmr2, N-terminal domain superfamily A3L04_09075 82dc802cef612b183e5aae1a429de73d 1061 Gene3D G3DSA:3.30.70.2220 467 612 5.4E-24 T 23-10-2018 IPR038242 Cmr2, N-terminal domain superfamily A3L04_09075 82dc802cef612b183e5aae1a429de73d 1061 TIGRFAM TIGR02577 cas_TM1794_Cmr2: CRISPR-associated protein Cas10/Cmr2, subtype III-B 265 897 3.6E-112 T 23-10-2018 IPR013407 CRISPR-associated protein Cmr2 A3L04_09075 82dc802cef612b183e5aae1a429de73d 1061 Pfam PF12469 CRISPR-associated protein 265 380 2.7E-30 T 23-10-2018 IPR024615 CRISPR-associated protein Cmr2, N-terminal A3L04_09360 e0d5dab9a0353109a9ab98eacff0e169 91 SUPERFAMILY SSF52540 4 91 5.31E-9 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09360 e0d5dab9a0353109a9ab98eacff0e169 91 Gene3D G3DSA:3.40.50.300 1 78 5.6E-11 T 23-10-2018 A3L04_09290 7981dcd977412b7fd2f20e69db5ed8c6 189 Gene3D G3DSA:3.50.30.50 1 188 4.2E-54 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A3L04_09290 7981dcd977412b7fd2f20e69db5ed8c6 189 Pfam PF04199 Putative cyclase 4 134 6.9E-20 T 23-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A3L04_09290 7981dcd977412b7fd2f20e69db5ed8c6 189 SUPERFAMILY SSF102198 2 188 1.96E-53 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A3L04_01830 71b6a8f618c38e7a9fae202a2ed72394 189 SUPERFAMILY SSF102114 18 81 1.9E-5 T 23-10-2018 A3L04_05160 4072ab1d00d36c90b37614c3a595e28c 311 Gene3D G3DSA:3.30.420.40 3 110 2.7E-71 T 23-10-2018 A3L04_05160 4072ab1d00d36c90b37614c3a595e28c 311 Gene3D G3DSA:3.30.420.40 111 279 2.7E-71 T 23-10-2018 A3L04_05160 4072ab1d00d36c90b37614c3a595e28c 311 SUPERFAMILY SSF53067 112 281 1.17E-43 T 23-10-2018 A3L04_05160 4072ab1d00d36c90b37614c3a595e28c 311 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 4 262 3.4E-34 T 23-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 A3L04_05160 4072ab1d00d36c90b37614c3a595e28c 311 SUPERFAMILY SSF53067 1 107 1.12E-12 T 23-10-2018 A3L04_02490 7d65cf8cc2bf73d9d87d52b6cd56eabd 445 Gene3D G3DSA:3.90.550.10 69 296 1.2E-40 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_02490 7d65cf8cc2bf73d9d87d52b6cd56eabd 445 Pfam PF13632 Glycosyl transferase family group 2 165 403 1.8E-24 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L04_02490 7d65cf8cc2bf73d9d87d52b6cd56eabd 445 SUPERFAMILY SSF53448 63 355 4.01E-50 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_09765 d700aac1e2264595c703640cb1f73801 125 SMART SM01405 4 124 2.0E-51 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_09765 d700aac1e2264595c703640cb1f73801 125 Hamap MF_00512 30S ribosomal protein S6e [rps6e]. 2 125 19.484 T 23-10-2018 IPR020924 Ribosomal protein S6e, archaeal GO:0003735|GO:0005840|GO:0006412 A3L04_09765 d700aac1e2264595c703640cb1f73801 125 ProSitePatterns PS00578 Ribosomal protein S6e signature. 63 74 - T 23-10-2018 IPR018282 Ribosomal protein S6e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_09765 d700aac1e2264595c703640cb1f73801 125 Pfam PF01092 Ribosomal protein S6e 4 124 5.9E-36 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_09825 efea56a8a18fe6555b8ec7cc85557d86 70 SUPERFAMILY SSF46785 3 55 5.94E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L04_09825 efea56a8a18fe6555b8ec7cc85557d86 70 Gene3D G3DSA:1.10.10.10 1 69 3.1E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_10510 2065a37fda6098bdcdeae3ac875c4a28 176 Pfam PF06510 Protein of unknown function (DUF1102) 37 174 5.2E-51 T 23-10-2018 IPR009482 Protein of unknown function DUF1102 A3L04_04895 277216e846630b9979276f4deb35585c 350 SUPERFAMILY SSF144052 5 332 3.4E-30 T 23-10-2018 A3L04_07050 61641907556ed83180076dfbcb93d421 537 Gene3D G3DSA:1.20.1730.10 6 533 7.4E-89 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily A3L04_07050 61641907556ed83180076dfbcb93d421 537 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 435 7.0E-75 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A3L04_07050 61641907556ed83180076dfbcb93d421 537 Pfam PF00474 Sodium:solute symporter family 33 435 7.4E-83 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A3L04_08285 550b4cfeacc05edeaf639b5a6e9cc8f0 131 TIGRFAM TIGR00307 eS8: ribosomal protein eS8 1 127 3.1E-47 T 23-10-2018 IPR001047 Ribosomal protein S8e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_08285 550b4cfeacc05edeaf639b5a6e9cc8f0 131 ProSitePatterns PS01193 Ribosomal protein S8e signature. 10 29 - T 23-10-2018 IPR018283 Ribosomal protein S8e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L04_08285 550b4cfeacc05edeaf639b5a6e9cc8f0 131 Pfam PF01201 Ribosomal protein S8e 2 125 5.5E-32 T 23-10-2018 IPR022309 Ribosomal protein S8e/ribosomal biogenesis NSA2 A3L04_08285 550b4cfeacc05edeaf639b5a6e9cc8f0 131 Hamap MF_00029 30S ribosomal protein S8e [rps8e]. 2 126 32.051 T 23-10-2018 IPR020919 Ribosomal protein S8e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L04_08285 550b4cfeacc05edeaf639b5a6e9cc8f0 131 Gene3D G3DSA:2.40.10.310 58 130 2.1E-32 T 23-10-2018 A3L04_10515 e5b412442aff7b5e2e6c0e5636bfc674 324 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 84 95 3.3E-5 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L04_10515 e5b412442aff7b5e2e6c0e5636bfc674 324 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 34 49 3.3E-5 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L04_10515 e5b412442aff7b5e2e6c0e5636bfc674 324 Pfam PF00717 Peptidase S24-like 33 92 3.3E-10 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A3L04_10515 e5b412442aff7b5e2e6c0e5636bfc674 324 SUPERFAMILY SSF51306 31 116 8.76E-11 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A3L04_10515 e5b412442aff7b5e2e6c0e5636bfc674 324 ProSitePatterns PS00501 Signal peptidases I serine active site. 36 43 - T 23-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 A3L04_10515 e5b412442aff7b5e2e6c0e5636bfc674 324 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 7 116 8.6E-20 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L04_00825 6e289a35425c82b6de5dc42538ab925a 475 Gene3D G3DSA:3.10.310.30 334 467 7.5E-11 T 23-10-2018 A3L04_00825 6e289a35425c82b6de5dc42538ab925a 475 SUPERFAMILY SSF64182 7 470 9.73E-66 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L04_00825 6e289a35425c82b6de5dc42538ab925a 475 Gene3D G3DSA:3.90.1640.30 3 220 5.1E-24 T 23-10-2018 A3L04_00825 6e289a35425c82b6de5dc42538ab925a 475 Pfam PF02272 DHHA1 domain 335 463 1.3E-21 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L04_02395 50d34e3a708149a886b64f08dbaed501 371 Pfam PF04123 Domain of unknown function (DUF373) 2 355 3.1E-100 T 23-10-2018 IPR007254 Protein of unknown function DUF373 A3L04_06245 45c195694a9af0248c924b7b1d77c08a 89 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 3 84 2.2E-13 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A3L04_01680 2edda4dd5992a8a16b9b4b41a5a20b7d 289 SUPERFAMILY SSF161098 11 286 4.06E-48 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_01680 2edda4dd5992a8a16b9b4b41a5a20b7d 289 Gene3D G3DSA:1.10.3720.10 7 277 4.5E-44 T 23-10-2018 IPR035906 MetI-like superfamily A3L04_06020 5ade5ef5add757d25bb7b4a300d61c2c 466 Pfam PF04415 Protein of unknown function (DUF515) 23 464 7.5E-167 T 23-10-2018 IPR007509 Protein of unknown function DUF515 A3L04_09200 991b8bd7a2b7df73e5a44b51a757257d 413 SUPERFAMILY SSF51905 1 385 1.08E-34 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_09200 991b8bd7a2b7df73e5a44b51a757257d 413 Gene3D G3DSA:3.90.660.50 83 353 1.5E-141 T 23-10-2018 A3L04_09200 991b8bd7a2b7df73e5a44b51a757257d 413 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 62 8.9E-12 T 23-10-2018 A3L04_09200 991b8bd7a2b7df73e5a44b51a757257d 413 Gene3D G3DSA:3.50.50.60 4 396 1.5E-141 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L04_06565 b19232bbf50dacfcc276d9f59b10ae69 207 Gene3D G3DSA:1.20.910.10 1 207 4.8E-64 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A3L04_06565 b19232bbf50dacfcc276d9f59b10ae69 207 Pfam PF03070 TENA/THI-4/PQQC family 8 203 2.0E-34 T 23-10-2018 IPR004305 Thiaminase-2/PQQC A3L04_06565 b19232bbf50dacfcc276d9f59b10ae69 207 SUPERFAMILY SSF48613 1 204 1.27E-59 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A3L04_01365 1d94c597f2fb5d0a88ecba0ff5278949 205 Pfam PF01873 Domain found in IF2B/IF5 2 34 2.6E-5 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L04_01365 1d94c597f2fb5d0a88ecba0ff5278949 205 SUPERFAMILY SSF75689 4 38 1.7E-5 T 23-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L04_01365 1d94c597f2fb5d0a88ecba0ff5278949 205 PIRSF PIRSF015877 1 198 6.7E-76 T 23-10-2018 IPR012041 Uncharacterised conserved protein UCP015877, zinc finger-containing A3L04_09010 c7ae56320078833142aef3848fb10304 442 SUPERFAMILY SSF52540 13 329 4.0E-25 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_09010 c7ae56320078833142aef3848fb10304 442 Gene3D G3DSA:3.40.50.300 6 242 1.4E-20 T 23-10-2018 A3L04_10365 2a8281d3fc6ca21ea0faaadfaa715e2c 331 Pfam PF01637 ATPase domain predominantly from Archaea 2 241 1.8E-67 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L04_10365 2a8281d3fc6ca21ea0faaadfaa715e2c 331 Gene3D G3DSA:3.40.50.300 1 202 1.4E-20 T 23-10-2018 A3L04_10365 2a8281d3fc6ca21ea0faaadfaa715e2c 331 Gene3D G3DSA:1.10.10.10 237 330 2.1E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_10365 2a8281d3fc6ca21ea0faaadfaa715e2c 331 SUPERFAMILY SSF52540 1 257 1.58E-26 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_10365 2a8281d3fc6ca21ea0faaadfaa715e2c 331 SMART SM00382 20 199 0.0022 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_07575 5bcb905f8095e975d827d8147d596fd5 172 SUPERFAMILY SSF143243 6 159 6.54E-29 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07575 5bcb905f8095e975d827d8147d596fd5 172 Gene3D G3DSA:3.30.460.80 7 133 3.1E-16 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07575 5bcb905f8095e975d827d8147d596fd5 172 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 88 143 1.0E-24 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07575 5bcb905f8095e975d827d8147d596fd5 172 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 35 150 6.5E-21 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_06070 4a4bef7b4f1a288fe85a26520b8a3982 222 Pfam PF01865 Protein of unknown function DUF47 6 220 3.7E-47 T 23-10-2018 IPR018445 Putative phosphate transport regulator A3L04_06070 4a4bef7b4f1a288fe85a26520b8a3982 222 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 5 220 2.1E-38 T 23-10-2018 IPR002727 Protein of unknown function DUF47 A3L04_06070 4a4bef7b4f1a288fe85a26520b8a3982 222 Gene3D G3DSA:1.20.58.220 1 222 1.4E-49 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L04_06070 4a4bef7b4f1a288fe85a26520b8a3982 222 SUPERFAMILY SSF109755 26 219 6.28E-17 T 23-10-2018 A3L04_07730 49e0a3677862c0e69fa658ed6a8fd989 264 SUPERFAMILY SSF54534 2 155 1.67E-41 T 23-10-2018 A3L04_07730 49e0a3677862c0e69fa658ed6a8fd989 264 Gene3D G3DSA:3.10.50.80 2 163 1.0E-50 T 23-10-2018 A3L04_07730 49e0a3677862c0e69fa658ed6a8fd989 264 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 153 5.4E-16 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A3L04_09115 dc8a1f30f867cdaf35499b589cc99b58 123 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 8 117 3.3E-25 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A3L04_09115 dc8a1f30f867cdaf35499b589cc99b58 123 TIGRFAM TIGR00494 crcB: protein CrcB 7 121 3.0E-28 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A3L04_09115 dc8a1f30f867cdaf35499b589cc99b58 123 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 6 122 20.079 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A3L04_02820 ffa7ee43871dc362c6e1e1c17f6c279e 310 Gene3D G3DSA:1.20.58.1130 7 193 3.4E-79 T 23-10-2018 A3L04_02820 ffa7ee43871dc362c6e1e1c17f6c279e 310 Gene3D G3DSA:1.20.1420.30 34 294 3.4E-79 T 23-10-2018 A3L04_02820 ffa7ee43871dc362c6e1e1c17f6c279e 310 Pfam PF01699 Sodium/calcium exchanger protein 162 302 6.8E-26 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A3L04_02820 ffa7ee43871dc362c6e1e1c17f6c279e 310 Pfam PF01699 Sodium/calcium exchanger protein 4 142 5.2E-24 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A3L04_02280 6bb5044e933be8500cbf9793b63748a3 356 Pfam PF05763 Protein of unknown function (DUF835) 232 353 8.5E-31 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L04_03315 483a1c2395bd8b67935cb73ee98a0b9e 252 Pfam PF13549 ATP-grasp domain 12 234 3.0E-83 T 23-10-2018 A3L04_03315 483a1c2395bd8b67935cb73ee98a0b9e 252 Gene3D G3DSA:3.30.1490.20 38 115 1.4E-93 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L04_03315 483a1c2395bd8b67935cb73ee98a0b9e 252 Gene3D G3DSA:3.30.470.20 17 232 1.4E-93 T 23-10-2018 A3L04_03315 483a1c2395bd8b67935cb73ee98a0b9e 252 SUPERFAMILY SSF56059 19 234 1.1E-46 T 23-10-2018 A3L04_07815 42baedd1363f298c18fa7a233baeb129 190 Pfam PF03167 Uracil DNA glycosylase superfamily 25 177 1.5E-46 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L04_07815 42baedd1363f298c18fa7a233baeb129 190 SMART SM00986 25 179 2.8E-38 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L04_07815 42baedd1363f298c18fa7a233baeb129 190 SMART SM00987 25 179 2.8E-38 T 23-10-2018 A3L04_07815 42baedd1363f298c18fa7a233baeb129 190 SUPERFAMILY SSF52141 3 186 3.01E-63 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L04_07815 42baedd1363f298c18fa7a233baeb129 190 Gene3D G3DSA:3.40.470.10 1 188 5.3E-74 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L04_07815 42baedd1363f298c18fa7a233baeb129 190 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 11 186 9.4E-82 T 23-10-2018 IPR005273 Uracil-DNA glycosylase family 4 A3L04_03280 5f33fe88c4b0242fa312822a215bca1c 137 Gene3D G3DSA:3.30.460.10 1 105 8.1E-15 T 23-10-2018 A3L04_03280 5f33fe88c4b0242fa312822a215bca1c 137 Pfam PF01909 Nucleotidyltransferase domain 10 72 3.7E-10 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L04_03280 5f33fe88c4b0242fa312822a215bca1c 137 SUPERFAMILY SSF81301 3 111 1.36E-16 T 23-10-2018 A3L04_08115 9d910c7fede315e4d9b57fc75dc3282c 114 SUPERFAMILY SSF117916 23 87 2.81E-12 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L04_08115 9d910c7fede315e4d9b57fc75dc3282c 114 Pfam PF01883 Iron-sulfur cluster assembly protein 25 86 1.9E-11 T 23-10-2018 IPR002744 MIP18 family-like A3L04_08115 9d910c7fede315e4d9b57fc75dc3282c 114 Gene3D G3DSA:3.30.300.130 16 106 1.4E-13 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L04_03870 635820aedd8202bc28851e8e1616aa15 314 Pfam PF02653 Branched-chain amino acid transport system / permease component 32 296 5.7E-37 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A3L04_07545 7794857aaa56a9ded34c1d0351f79da8 113 Pfam PF09685 Domain of unknown function (DUF4870) 20 99 1.0E-8 T 23-10-2018 IPR019109 Protein of unknown function DUF4870 A3L04_05825 8ff3ca74b04cd0ee0853a43a6efb63df 430 Pfam PF09852 Predicted membrane protein (DUF2079) 23 393 1.8E-52 T 23-10-2018 IPR018650 Sulfolobus virus STSV1, Orf64 A3L04_00965 ec80bd6114e26da43f85d4531c96efe2 114 SUPERFAMILY SSF52540 3 84 2.76E-7 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_00965 ec80bd6114e26da43f85d4531c96efe2 114 Gene3D G3DSA:3.40.50.300 1 106 4.2E-6 T 23-10-2018 A3L04_00565 9e3ff3c727e684b1cc6327321011eca9 57 Pfam PF07754 Domain of unknown function (DUF1610) 8 31 2.1E-14 T 23-10-2018 IPR011668 Domain of unknown function DUF1610 A3L04_09725 0c4edabd6729f5cc02bb3949781948bc 490 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 24 174 4.0E-7 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A3L04_00945 e833c2913618ad86eb464b4cb5623140 430 Hamap MF_01908 Cyclic 2,3-diphosphoglycerate synthetase [cpgS]. 1 429 47.098 T 23-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 A3L04_00945 e833c2913618ad86eb464b4cb5623140 430 Gene3D G3DSA:3.40.50.300 114 323 4.1E-10 T 23-10-2018 A3L04_00945 e833c2913618ad86eb464b4cb5623140 430 SUPERFAMILY SSF52540 129 309 1.93E-5 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_00945 e833c2913618ad86eb464b4cb5623140 430 PIRSF PIRSF009445 1 430 1.8E-198 T 23-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 A3L04_10670 14bcc1b9f1228c3b6d417f26fa59cbb6 84 Gene3D G3DSA:3.10.20.30 2 73 6.1E-14 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L04_10670 14bcc1b9f1228c3b6d417f26fa59cbb6 84 SUPERFAMILY SSF54285 16 73 2.24E-10 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L04_10670 14bcc1b9f1228c3b6d417f26fa59cbb6 84 Pfam PF02597 ThiS family 6 73 4.9E-11 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L04_07695 aa9b6b332d773a826444ada9926b0f38 706 SUPERFAMILY SSF53850 115 196 3.26E-7 T 23-10-2018 A3L04_07695 aa9b6b332d773a826444ada9926b0f38 706 SUPERFAMILY SSF53850 212 693 5.02E-91 T 23-10-2018 A3L04_07695 aa9b6b332d773a826444ada9926b0f38 706 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 258 695 8.3E-73 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain A3L04_07695 aa9b6b332d773a826444ada9926b0f38 706 Gene3D G3DSA:3.10.105.10 109 171 3.5E-5 T 23-10-2018 A3L04_07695 aa9b6b332d773a826444ada9926b0f38 706 Gene3D G3DSA:3.40.190.10 172 185 3.5E-5 T 23-10-2018 A3L04_07695 aa9b6b332d773a826444ada9926b0f38 706 Gene3D G3DSA:3.10.105.10 536 704 5.9E-46 T 23-10-2018 A3L04_07695 aa9b6b332d773a826444ada9926b0f38 706 PIRSF PIRSF002741 208 423 8.2E-12 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A3L04_07695 aa9b6b332d773a826444ada9926b0f38 706 PIRSF PIRSF002741 422 703 1.3E-55 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A3L04_07695 aa9b6b332d773a826444ada9926b0f38 706 PIRSF PIRSF002741 95 199 0.0024 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A3L04_00035 c12ae937b5559116bb2779c8743b730f 166 Pfam PF03692 Putative zinc- or iron-chelating domain 15 126 5.0E-19 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein A3L04_07450 cc8abc547ac030137dc2f113d18aea6f 546 Gene3D G3DSA:1.50.10.10 173 514 4.4E-32 T 23-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A3L04_07450 cc8abc547ac030137dc2f113d18aea6f 546 Pfam PF06202 Amylo-alpha-1,6-glucosidase 176 508 8.9E-5 T 23-10-2018 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 A3L04_07450 cc8abc547ac030137dc2f113d18aea6f 546 SUPERFAMILY SSF48208 176 512 1.23E-51 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A3L04_02140 1499b36dca519b76ecccb878fa8d60ba 192 Gene3D G3DSA:1.20.1260.10 22 172 6.3E-29 T 23-10-2018 IPR012347 Ferritin-like A3L04_02140 1499b36dca519b76ecccb878fa8d60ba 192 Pfam PF02915 Rubrerythrin 32 168 1.0E-24 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L04_02140 1499b36dca519b76ecccb878fa8d60ba 192 SUPERFAMILY SSF47240 24 174 1.35E-20 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L04_01875 24ba0c04bd5ca703d66b1073019506bc 92 Gene3D G3DSA:3.40.50.300 1 89 1.0E-5 T 23-10-2018 A3L04_08700 4b4b97156fecf5f0c9e1fe30d43caa19 926 Pfam PF05124 S-layer like family, C-terminal region 817 892 8.1E-15 T 23-10-2018 IPR022651 S-layer protein, C-terminal A3L04_08700 4b4b97156fecf5f0c9e1fe30d43caa19 926 SUPERFAMILY SSF103647 604 653 9.15E-6 T 23-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 A3L04_08700 4b4b97156fecf5f0c9e1fe30d43caa19 926 TIGRFAM TIGR01564 S_layer_MJ: S-layer protein 820 890 1.4E-7 T 23-10-2018 IPR006454 S-layer protein GO:0005618 A3L04_02345 8e6b1e6a3a60992e7aa6f6708fcf29f1 419 PRINTS PR00758 Arsenical pump membrane protein signature 101 125 2.0E-18 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L04_02345 8e6b1e6a3a60992e7aa6f6708fcf29f1 419 PRINTS PR00758 Arsenical pump membrane protein signature 317 339 2.0E-18 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L04_02345 8e6b1e6a3a60992e7aa6f6708fcf29f1 419 PRINTS PR00758 Arsenical pump membrane protein signature 390 414 2.0E-18 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L04_02345 8e6b1e6a3a60992e7aa6f6708fcf29f1 419 PRINTS PR00758 Arsenical pump membrane protein signature 216 241 2.0E-18 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L04_02345 8e6b1e6a3a60992e7aa6f6708fcf29f1 419 PRINTS PR00758 Arsenical pump membrane protein signature 273 297 2.0E-18 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L04_02345 8e6b1e6a3a60992e7aa6f6708fcf29f1 419 PRINTS PR00758 Arsenical pump membrane protein signature 357 382 2.0E-18 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L04_02345 8e6b1e6a3a60992e7aa6f6708fcf29f1 419 Pfam PF03600 Citrate transporter 16 361 1.6E-55 T 23-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 A3L04_10810 63f0e4f17221be965731f13ee29a679c 353 Pfam PF05763 Protein of unknown function (DUF835) 223 347 4.4E-31 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L04_00645 880ee25fc61a6877de7a0fddacf03c02 201 Pfam PF14358 Domain of unknown function (DUF4405) 10 73 1.9E-16 T 23-10-2018 IPR025517 Domain of unknown function DUF4405 A3L04_06330 8bcc5b7481985d1efcc499bcafa6998f 105 Gene3D G3DSA:1.10.10.10 34 105 1.8E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L04_04225 1377d4867e50b573af916c5291b5cf55 396 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 294 388 1.0E-18 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A3L04_04225 1377d4867e50b573af916c5291b5cf55 396 SUPERFAMILY SSF52518 23 278 6.38E-66 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L04_04225 1377d4867e50b573af916c5291b5cf55 396 Gene3D G3DSA:3.40.50.920 282 395 6.7E-23 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L04_04225 1377d4867e50b573af916c5291b5cf55 396 SUPERFAMILY SSF52922 286 393 1.43E-23 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L04_04225 1377d4867e50b573af916c5291b5cf55 396 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 34 270 3.8E-77 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L04_04225 1377d4867e50b573af916c5291b5cf55 396 Gene3D G3DSA:3.40.50.970 9 211 2.1E-75 T 23-10-2018 A3L04_09870 d3a3a22ccaf497e61246a86d2db09a24 63 Pfam PF04021 Class III signal peptide 2 28 1.9E-9 T 23-10-2018 IPR007166 Class III signal peptide motif A3L04_09505 0229bf071ae791f80d1d98184e2ea1bd 116 Pfam PF03008 Archaea bacterial proteins of unknown function 31 116 3.2E-26 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L04_09875 296b6eed0314c37cae8b3ede1ed8d87e 64 Pfam PF04021 Class III signal peptide 2 27 1.4E-5 T 23-10-2018 IPR007166 Class III signal peptide motif A3L04_06235 8382dc307313b6ee7d57c86660b9645b 152 Pfam PF13244 Domain of unknown function (DUF4040) 8 71 6.0E-12 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A3L04_04195 3584fd18447cb4871f0ab603ab498524 364 Pfam PF08969 USP8 dimerisation domain 225 300 3.0E-6 T 23-10-2018 IPR015063 USP8 dimerisation domain A3L04_04195 3584fd18447cb4871f0ab603ab498524 364 Gene3D G3DSA:3.40.50.12090 28 122 4.8E-5 T 23-10-2018 A3L04_05575 ea8b00f712e8f3d259c615b573a5cc98 102 Pfam PF04242 Protein of unknown function (DUF424) 10 100 1.2E-31 T 23-10-2018 IPR007355 Protein of unknown function DUF424 A3L04_05575 ea8b00f712e8f3d259c615b573a5cc98 102 Gene3D G3DSA:3.30.1860.10 2 100 4.5E-34 T 23-10-2018 A3L04_10025 a409a00da8848b12b21ea7a3a247cc1f 440 Pfam PF00999 Sodium/hydrogen exchanger family 11 414 3.6E-51 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L04_10025 a409a00da8848b12b21ea7a3a247cc1f 440 Gene3D G3DSA:1.20.1530.20 5 416 8.1E-22 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L04_01825 e5e9bbf3141e8cedf15530dd5bcb9dc3 389 Pfam PF07690 Major Facilitator Superfamily 12 294 5.8E-37 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L04_01825 e5e9bbf3141e8cedf15530dd5bcb9dc3 389 Pfam PF07690 Major Facilitator Superfamily 296 377 1.5E-8 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L04_01825 e5e9bbf3141e8cedf15530dd5bcb9dc3 389 SUPERFAMILY SSF103473 6 378 1.57E-58 T 23-10-2018 IPR036259 MFS transporter superfamily A3L04_01825 e5e9bbf3141e8cedf15530dd5bcb9dc3 389 PRINTS PR01035 Tetracycline resistance protein signature 134 156 1.2E-7 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A3L04_01825 e5e9bbf3141e8cedf15530dd5bcb9dc3 389 PRINTS PR01035 Tetracycline resistance protein signature 296 316 1.2E-7 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A3L04_01825 e5e9bbf3141e8cedf15530dd5bcb9dc3 389 PRINTS PR01035 Tetracycline resistance protein signature 16 32 1.2E-7 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A3L04_01825 e5e9bbf3141e8cedf15530dd5bcb9dc3 389 Gene3D G3DSA:1.20.1250.20 4 378 1.2E-51 T 23-10-2018 A3L04_02135 516ef5cfbc86db0c8bf0fbf0009781e6 174 SUPERFAMILY SSF117916 75 172 1.57E-33 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L04_02135 516ef5cfbc86db0c8bf0fbf0009781e6 174 Gene3D G3DSA:3.30.300.130 71 174 1.1E-37 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L04_02135 516ef5cfbc86db0c8bf0fbf0009781e6 174 Pfam PF01883 Iron-sulfur cluster assembly protein 78 151 5.7E-22 T 23-10-2018 IPR002744 MIP18 family-like A3L04_01045 46fce8fb8a0c8e233892e2f8f3dbe9a9 225 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 4 45 1.1E-10 T 23-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal A3L04_01045 46fce8fb8a0c8e233892e2f8f3dbe9a9 225 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 25 148 4.2E-10 T 23-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 A3L04_01045 46fce8fb8a0c8e233892e2f8f3dbe9a9 225 Gene3D G3DSA:3.30.70.2660 10 195 6.3E-10 T 23-10-2018 A3L04_07190 e7a6e32190138dc26554254529f91a85 1076 Pfam PF10102 Domain of unknown function (DUF2341) 524 590 2.9E-12 T 23-10-2018 IPR018765 Domain of unknown function DUF2341 A3L04_01355 b869d756faefad079df2d6cf3fc1b9ad 231 Pfam PF01940 Integral membrane protein DUF92 8 219 7.0E-50 T 23-10-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 A3L04_05025 9b25d5afc41e98988a4ce5a724afbd07 316 Pfam PF05763 Protein of unknown function (DUF835) 205 311 1.6E-31 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L04_00855 32a9671698a5a9686615db224a40d1c2 243 Pfam PF10869 Protein of unknown function (DUF2666) 125 242 4.6E-40 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A3L04_00855 32a9671698a5a9686615db224a40d1c2 243 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 2 78 6.0E-12 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A3L04_00855 32a9671698a5a9686615db224a40d1c2 243 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 125 242 2.0E-39 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A3L04_05970 adc9a7641197aa5ec49791cb1c21258f 216 SUPERFAMILY SSF74784 1 182 4.05E-40 T 23-10-2018 IPR036081 Translin superfamily GO:0043565 Reactome: R-HSA-426486 A3L04_05970 adc9a7641197aa5ec49791cb1c21258f 216 Gene3D G3DSA:1.20.58.2140 2 202 1.2E-65 T 23-10-2018 A3L04_05970 adc9a7641197aa5ec49791cb1c21258f 216 Pfam PF01997 Translin family 21 181 2.8E-15 T 23-10-2018 IPR002848 Translin family GO:0043565 Reactome: R-HSA-426486 A3L04_10310 3ec75f97f27b68325f894a65bd3a6ed5 190 SMART SM01022 4 104 3.0E-24 T 23-10-2018 IPR007374 ASCH domain A3L04_10310 3ec75f97f27b68325f894a65bd3a6ed5 190 SUPERFAMILY SSF88697 2 103 2.32E-22 T 23-10-2018 IPR015947 PUA-like superfamily A3L04_10310 3ec75f97f27b68325f894a65bd3a6ed5 190 Pfam PF04266 ASCH domain 4 103 6.8E-16 T 23-10-2018 IPR007374 ASCH domain A3L04_01145 85720f57e9cad8702040b5b6ff95804c 153 SUPERFAMILY SSF53271 3 145 1.26E-35 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L04_01145 85720f57e9cad8702040b5b6ff95804c 153 Gene3D G3DSA:3.40.50.2020 1 153 5.1E-56 T 23-10-2018 A3L04_01145 85720f57e9cad8702040b5b6ff95804c 153 Pfam PF00156 Phosphoribosyl transferase domain 13 149 2.5E-30 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L04_05895 c9219101e4334ff0cc57b329e3339d9c 349 SUPERFAMILY SSF53901 174 347 4.98E-47 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L04_05895 c9219101e4334ff0cc57b329e3339d9c 349 SUPERFAMILY SSF53901 9 168 5.35E-35 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L04_05895 c9219101e4334ff0cc57b329e3339d9c 349 Gene3D G3DSA:3.40.47.10 7 348 2.1E-76 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L04_05895 c9219101e4334ff0cc57b329e3339d9c 349 TIGRFAM TIGR00748 HMG_CoA_syn_Arc: putative hydroxymethylglutaryl-CoA synthase 10 348 6.6E-200 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related A3L04_05895 c9219101e4334ff0cc57b329e3339d9c 349 Hamap MF_01409 UPF0219 protein . 9 349 62.407 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related A3L04_05895 c9219101e4334ff0cc57b329e3339d9c 349 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 109 170 1.8E-5 T 23-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A3L04_05895 c9219101e4334ff0cc57b329e3339d9c 349 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 223 302 1.1E-11 T 23-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A3L04_02760 93310a76163b2060d88f6de31102e95c 432 Pfam PF03787 RAMP superfamily 8 177 3.5E-11 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein A3L04_02760 93310a76163b2060d88f6de31102e95c 432 TIGRFAM TIGR01894 cas_TM1795_cmr1: CRISPR type III-B/RAMP module RAMP protein Cmr1 8 179 2.2E-24 T 23-10-2018 IPR007522 CRISPR-associated protein TM1795 A3L04_09300 7edda56b1f635148abe4ec89c598e7fe 126 SUPERFAMILY SSF55298 1 125 1.73E-53 T 23-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A3L04_09300 7edda56b1f635148abe4ec89c598e7fe 126 Gene3D G3DSA:3.30.1330.40 1 126 4.8E-62 T 23-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A3L04_09300 7edda56b1f635148abe4ec89c598e7fe 126 Pfam PF01042 Endoribonuclease L-PSP 8 124 8.1E-50 T 23-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 A3L04_09300 7edda56b1f635148abe4ec89c598e7fe 126 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 101 119 - T 23-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 A3L04_09300 7edda56b1f635148abe4ec89c598e7fe 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 124 2.3E-57 T 23-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 A3L04_10545 238cf72e431234191ae22e0a7266a92a 232 Gene3D G3DSA:3.40.50.300 3 232 2.4E-43 T 23-10-2018 A3L04_10545 238cf72e431234191ae22e0a7266a92a 232 SUPERFAMILY SSF52540 3 224 2.26E-26 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_10545 238cf72e431234191ae22e0a7266a92a 232 Pfam PF06745 KaiC 16 223 1.3E-15 T 23-10-2018 IPR014774 KaiC-like domain A3L04_02215 35f789ef30f94409c8fb146cc0d3490c 153 Gene3D G3DSA:3.30.479.10 5 148 8.7E-36 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 A3L04_02215 35f789ef30f94409c8fb146cc0d3490c 153 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 9 147 4.9E-29 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A3L04_02215 35f789ef30f94409c8fb146cc0d3490c 153 SUPERFAMILY SSF55620 7 147 3.0E-36 T 23-10-2018 A3L04_04435 f24974133a536e5f5d053978c3cefac9 93 SUPERFAMILY SSF82649 5 79 2.56E-9 T 23-10-2018 A3L04_04435 f24974133a536e5f5d053978c3cefac9 93 Gene3D G3DSA:3.30.390.50 1 87 7.3E-25 T 23-10-2018 A3L04_04435 f24974133a536e5f5d053978c3cefac9 93 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 6 63 2.1E-7 T 23-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 A3L04_02170 9c440031e3b94da30258a6f837d2b941 129 Pfam PF01850 PIN domain 2 121 9.8E-10 T 23-10-2018 IPR002716 PIN domain A3L04_02170 9c440031e3b94da30258a6f837d2b941 129 SUPERFAMILY SSF88723 2 123 5.33E-16 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L04_02170 9c440031e3b94da30258a6f837d2b941 129 Gene3D G3DSA:3.40.50.1010 1 125 7.8E-29 T 23-10-2018 A3L04_06045 42289d5164c4197278926bcdcc90df1e 227 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 19 219 3.4E-71 T 23-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 A3L04_06045 42289d5164c4197278926bcdcc90df1e 227 Gene3D G3DSA:3.90.850.10 4 223 2.2E-91 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A3L04_06045 42289d5164c4197278926bcdcc90df1e 227 SUPERFAMILY SSF56529 14 222 1.44E-79 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A3L04_06615 195fcf20f8c53dfdd851db98ae314570 223 Pfam PF01963 TraB family 153 212 2.8E-7 T 23-10-2018 IPR002816 Pheromone shutdown, TraB A3L04_01620 2e6c649fa3fc8cf3900d3c235083c1fa 374 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 7 361 2.5E-36 T 23-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane A3L04_06670 d7dd09f13d1c55520fe6ba4180c89d8e 199 SUPERFAMILY SSF47240 116 193 8.12E-5 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L04_01595 1081fa7cee97df13d9b9b12b116abf80 148 Gene3D G3DSA:3.90.1170.40 5 140 2.9E-49 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A3L04_01595 1081fa7cee97df13d9b9b12b116abf80 148 SUPERFAMILY SSF54690 12 140 3.27E-46 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A3L04_01595 1081fa7cee97df13d9b9b12b116abf80 148 Pfam PF02391 MoaE protein 12 121 2.8E-37 T 23-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A3L04_02700 9f7286459ba0e8e6e6a6db4d386a9220 371 SUPERFAMILY SSF53448 1 250 2.25E-43 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_02700 9f7286459ba0e8e6e6a6db4d386a9220 371 Gene3D G3DSA:3.90.550.10 1 223 1.9E-53 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_02700 9f7286459ba0e8e6e6a6db4d386a9220 371 Pfam PF00535 Glycosyl transferase family 2 4 165 7.2E-30 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L04_07600 d76a2d0f5feff8bb976f04c8872758dd 148 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 8 134 1.0E-27 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A3L04_02450 1cb47e5c2b69bbf069625d820a212920 92 SUPERFAMILY SSF90257 7 73 2.88E-5 T 23-10-2018 A3L04_03040 99676dd0c946d158bcfc34677258ed7b 272 PIRSF PIRSF006648 2 262 2.7E-17 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L04_03040 99676dd0c946d158bcfc34677258ed7b 272 Pfam PF01061 ABC-2 type transporter 31 227 1.1E-17 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A3L04_03040 99676dd0c946d158bcfc34677258ed7b 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 186 205 9.9E-8 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L04_03040 99676dd0c946d158bcfc34677258ed7b 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 149 173 9.9E-8 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L04_03040 99676dd0c946d158bcfc34677258ed7b 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 206 225 9.9E-8 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L04_06940 84b0626be657d4bf077585939d2ea2f3 446 Pfam PF01458 Uncharacterized protein family (UPF0051) 195 418 2.6E-56 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A3L04_06940 84b0626be657d4bf077585939d2ea2f3 446 SUPERFAMILY SSF101960 16 442 7.06E-105 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily A3L04_03875 1ec8b8e07530d264bf3ee77131215f26 302 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 266 5.2E-41 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A3L04_02975 9410765908cbb249b0f3690bb5c105d8 241 Pfam PF08241 Methyltransferase domain 46 141 7.3E-29 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A3L04_02975 9410765908cbb249b0f3690bb5c105d8 241 Gene3D G3DSA:3.40.50.150 5 239 4.8E-46 T 23-10-2018 A3L04_02975 9410765908cbb249b0f3690bb5c105d8 241 SUPERFAMILY SSF53335 6 218 6.27E-50 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L04_09775 777b747feb117d7afe8c33a8770479fe 248 Pfam PF09883 Uncharacterized protein conserved in archaea (DUF2110) 6 233 2.1E-73 T 23-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 A3L04_09775 777b747feb117d7afe8c33a8770479fe 248 PIRSF PIRSF019322 1 244 4.2E-106 T 23-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 A3L04_07925 a6f406d48c9ae78a6a33a619a3a42007 195 Gene3D G3DSA:1.20.1540.10 3 189 5.5E-36 T 23-10-2018 IPR035952 Rhomboid-like superfamily A3L04_07925 a6f406d48c9ae78a6a33a619a3a42007 195 SUPERFAMILY SSF144091 5 185 6.41E-38 T 23-10-2018 A3L04_07925 a6f406d48c9ae78a6a33a619a3a42007 195 Pfam PF01694 Rhomboid family 46 181 8.1E-28 T 23-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A3L04_06050 13901bfa864dc2b61854fb330ac0a81f 262 Gene3D G3DSA:3.60.110.10 1 262 1.4E-106 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A3L04_06050 13901bfa864dc2b61854fb330ac0a81f 262 SUPERFAMILY SSF56317 1 260 1.83E-75 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A3L04_06050 13901bfa864dc2b61854fb330ac0a81f 262 Pfam PF00795 Carbon-nitrogen hydrolase 3 238 1.8E-58 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A3L04_01930 d52099fdd6d7c14b46045285a437b807 190 Gene3D G3DSA:1.10.1760.20 2 190 1.3E-20 T 23-10-2018 A3L04_01930 d52099fdd6d7c14b46045285a437b807 190 Pfam PF12822 ECF transporter, substrate-specific component 6 182 2.7E-7 T 23-10-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 A3L04_02970 2e00c0b2958ccada681a6dcd187acd27 372 Pfam PF01497 Periplasmic binding protein 65 314 1.9E-40 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain A3L04_02970 2e00c0b2958ccada681a6dcd187acd27 372 SUPERFAMILY SSF53807 38 367 7.46E-60 T 23-10-2018 A3L04_02970 2e00c0b2958ccada681a6dcd187acd27 372 Gene3D G3DSA:3.40.50.1980 35 370 1.9E-103 T 23-10-2018 A3L04_04180 fbc0973721ac434a455218e2cc1baed5 480 Pfam PF07885 Ion channel 404 479 2.0E-12 T 23-10-2018 IPR013099 Potassium channel domain A3L04_04180 fbc0973721ac434a455218e2cc1baed5 480 SUPERFAMILY SSF81324 375 479 5.1E-15 T 23-10-2018 A3L04_04180 fbc0973721ac434a455218e2cc1baed5 480 Gene3D G3DSA:1.10.287.70 396 480 2.0E-13 T 23-10-2018 A3L04_06715 eda8a93da07aced103f3b27310431476 113 Pfam PF02643 Uncharacterized ACR, COG1430 14 113 7.8E-18 T 23-10-2018 IPR003795 Protein of unknown function DUF192 A3L04_06715 eda8a93da07aced103f3b27310431476 113 Hamap MF_00263 UPF0127 protein . 2 113 31.651 T 23-10-2018 IPR022906 Uncharacterised protein family UPF0127 A3L04_06715 eda8a93da07aced103f3b27310431476 113 Gene3D G3DSA:2.60.120.1140 3 113 9.3E-11 T 23-10-2018 IPR038695 Saro_0823-like superfamily A3L04_07625 0f5707d7894033726c39a8bb0f08b625 167 PIRSF PIRSF019239 1 166 4.4E-40 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L04_07625 0f5707d7894033726c39a8bb0f08b625 167 Pfam PF01899 Na+/H+ ion antiporter subunit 7 164 1.7E-43 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L04_08070 40a645abd5ecc25cdb1709904b9b74b9 109 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 10 106 6.8E-20 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A3L04_08075 594f685e3b732850bbd0f56cf805e627 160 Pfam PF01899 Na+/H+ ion antiporter subunit 7 158 1.4E-38 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L04_08075 594f685e3b732850bbd0f56cf805e627 160 PIRSF PIRSF019239 1 160 1.3E-38 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L04_01965 5603a4390e0c649136066a6ad8ca5ca5 340 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 10 321 1.3E-56 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L04_01965 5603a4390e0c649136066a6ad8ca5ca5 340 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 9 326 5.3E-62 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L04_04610 f5b78cd496e06e197d33ddbd6052ed78 118 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 4 108 1.4E-22 T 23-10-2018 IPR019277 Protein of unknown function DUF2304 A3L04_06505 4cacec6dfa081b5913411cd9b3a0f352 317 Pfam PF01384 Phosphate transporter family 18 303 1.4E-62 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A3L04_06105 432e34757710458191ebdea229a1f4c6 111 Pfam PF01883 Iron-sulfur cluster assembly protein 16 53 4.8E-5 T 23-10-2018 IPR002744 MIP18 family-like A3L04_09795 41eff6ad382dea86dd8661ad40d94c47 657 Pfam PF04312 Protein of unknown function (DUF460) 204 344 5.1E-50 T 23-10-2018 IPR007408 Protein of unknown function DUF460 A3L04_00900 add5c7a1c24591d03feaa9aee7609540 195 SUPERFAMILY SSF53448 14 139 5.04E-8 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_00900 add5c7a1c24591d03feaa9aee7609540 195 Gene3D G3DSA:3.90.550.10 10 192 5.2E-16 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L04_10350 a41647c142e3344533d4f080f70f3526 256 Pfam PF12146 Serine aminopeptidase, S33 10 239 4.7E-67 T 23-10-2018 IPR022742 Serine aminopeptidase, S33 A3L04_10350 a41647c142e3344533d4f080f70f3526 256 Gene3D G3DSA:3.40.50.1820 3 256 2.5E-67 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L04_10350 a41647c142e3344533d4f080f70f3526 256 PRINTS PR00111 Alpha/beta hydrolase fold signature 39 54 5.3E-7 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A3L04_10350 a41647c142e3344533d4f080f70f3526 256 PRINTS PR00111 Alpha/beta hydrolase fold signature 194 208 5.3E-7 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A3L04_10350 a41647c142e3344533d4f080f70f3526 256 PRINTS PR00111 Alpha/beta hydrolase fold signature 82 95 5.3E-7 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A3L04_10350 a41647c142e3344533d4f080f70f3526 256 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 5.3E-7 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A3L04_10350 a41647c142e3344533d4f080f70f3526 256 SUPERFAMILY SSF53474 8 254 2.13E-50 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L04_01565 bcb66a8939eeaafe1f9d2ce1094f0412 151 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 125 4.4E-11 T 23-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase A3L04_06485 89413f8c37c04c6d2972805f5edcb668 138 Pfam PF09999 Uncharacterized protein conserved in archaea (DUF2240) 23 135 6.4E-7 T 23-10-2018 IPR018716 Protein of unknown function DUF2240 A3L04_09680 93f1c7b913f52409584183390889de67 168 Pfam PF01864 CDP-archaeol synthase 4 168 1.8E-57 T 23-10-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 A3L04_09680 93f1c7b913f52409584183390889de67 168 Hamap MF_01117 CDP-archaeol synthase [carS]. 11 168 28.347 T 23-10-2018 IPR002726 CDP-archaeol synthase, archaea KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 A3L04_09880 299055c9ae519fe058d574e8df4d174e 648 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 57 203 7.6E-6 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A3L04_01410 60f1371a1f97f18a4d351354daa55cd0 260 Pfam PF00005 ABC transporter 18 162 1.5E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L04_01410 60f1371a1f97f18a4d351354daa55cd0 260 Gene3D G3DSA:3.40.50.300 1 254 1.2E-72 T 23-10-2018 A3L04_01410 60f1371a1f97f18a4d351354daa55cd0 260 SMART SM00382 26 211 6.6E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L04_01410 60f1371a1f97f18a4d351354daa55cd0 260 SUPERFAMILY SSF52540 2 220 2.49E-66 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_01410 60f1371a1f97f18a4d351354daa55cd0 260 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L04_09260 8970d156bd1fd04a8ca831a0da44fb31 231 Gene3D G3DSA:3.20.20.370 1 230 1.7E-41 T 23-10-2018 A3L04_09260 8970d156bd1fd04a8ca831a0da44fb31 231 Pfam PF01522 Polysaccharide deacetylase 3 124 1.8E-19 T 23-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A3L04_09260 8970d156bd1fd04a8ca831a0da44fb31 231 SUPERFAMILY SSF88713 3 226 7.79E-36 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L04_06005 1275d2fd1e956b9023fa96d0e08e1f3f 354 Pfam PF00482 Type II secretion system (T2SS), protein F 186 310 2.8E-22 T 23-10-2018 IPR018076 Type II secretion system F domain A3L04_06005 1275d2fd1e956b9023fa96d0e08e1f3f 354 Gene3D G3DSA:1.20.81.30 174 285 9.1E-12 T 23-10-2018 A3L04_06065 2e277eebf26b57c756f69e266c13b821 406 Pfam PF01384 Phosphate transporter family 21 394 3.1E-111 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A3L04_00075 499e49e43eb3525750bc92049488416b 111 Pfam PF12698 ABC-2 family transporter protein 21 106 2.1E-10 T 23-10-2018 A3L04_08870 7596f395276ec9499eec5549f8734e86 191 Pfam PF05763 Protein of unknown function (DUF835) 79 188 4.0E-29 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L04_07115 1e1ace22dae83ecad313de7319796008 435 Pfam PF13635 Domain of unknown function (DUF4143) 227 364 2.7E-8 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 A3L04_07115 1e1ace22dae83ecad313de7319796008 435 Pfam PF13173 AAA domain 35 167 1.1E-38 T 23-10-2018 A3L04_07115 1e1ace22dae83ecad313de7319796008 435 Gene3D G3DSA:3.40.50.300 65 154 6.6E-8 T 23-10-2018 A3L04_07115 1e1ace22dae83ecad313de7319796008 435 SUPERFAMILY SSF52540 35 225 1.7E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_05645 da993cbcc86d9c6f33b46a24e69b4f88 101 Gene3D G3DSA:2.40.30.10 11 94 2.1E-7 T 23-10-2018 A3L04_05645 da993cbcc86d9c6f33b46a24e69b4f88 101 SUPERFAMILY SSF50447 14 90 8.99E-6 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L04_04490 0ff09208f5c6ea96208a6d3e0dcebed8 133 Pfam PF04009 Protein of unknown function (DUF356) 5 110 3.1E-36 T 23-10-2018 IPR007154 Protein of unknown function DUF356 A3L04_04490 0ff09208f5c6ea96208a6d3e0dcebed8 133 PIRSF PIRSF006606 3 128 3.3E-52 T 23-10-2018 IPR007154 Protein of unknown function DUF356 A3L04_10755 72305c7132afb0fadc1ba62a733db277 315 SUPERFAMILY SSF53807 22 273 9.32E-36 T 23-10-2018 A3L04_10755 72305c7132afb0fadc1ba62a733db277 315 Pfam PF01297 Zinc-uptake complex component A periplasmic 26 267 2.5E-21 T 23-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 A3L04_10755 72305c7132afb0fadc1ba62a733db277 315 Gene3D G3DSA:3.40.50.1980 16 164 3.0E-22 T 23-10-2018 A3L04_07455 6b50e7ff20ca50247b51eb99d8e1bc06 480 SUPERFAMILY SSF53743 2 319 6.15E-40 T 23-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 A3L04_07455 6b50e7ff20ca50247b51eb99d8e1bc06 480 Pfam PF02952 L-fucose isomerase, C-terminal domain 337 468 1.3E-28 T 23-10-2018 IPR015888 L-fucose isomerase, C-terminal GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 A3L04_00700 285c608f041bafaf26bd585c9340b990 121 SUPERFAMILY SSF51182 11 108 4.18E-27 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L04_00700 285c608f041bafaf26bd585c9340b990 121 Pfam PF07883 Cupin domain 38 106 6.1E-17 T 23-10-2018 IPR013096 Cupin 2, conserved barrel A3L04_00700 285c608f041bafaf26bd585c9340b990 121 Gene3D G3DSA:2.60.120.10 1 119 7.5E-34 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L04_06360 e93e31bccf7e810d7e9e462050ae9552 222 Gene3D G3DSA:3.40.50.300 4 188 1.4E-5 T 23-10-2018 A3L04_06360 e93e31bccf7e810d7e9e462050ae9552 222 Pfam PF02183 Homeobox associated leucine zipper 69 109 1.1E-6 T 23-10-2018 IPR003106 Leucine zipper, homeobox-associated GO:0003700|GO:0006355|GO:0043565 Reactome: R-HSA-432722|Reactome: R-HSA-6807878 A3L04_09570 1f7e5a3fcf595eb38545088cc09fb98c 254 Gene3D G3DSA:3.40.50.300 1 253 5.9E-71 T 23-10-2018 A3L04_04260 301becfcf37ed14af9d39090073ec0e2 153 Pfam PF06695 Putative small multi-drug export protein 16 142 3.3E-27 T 23-10-2018 IPR009577 Putative small multi-drug export A3L04_08560 79fd1a163cff9a4eee4fc45864c7053b 288 SUPERFAMILY SSF52540 28 282 8.04E-25 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_08560 79fd1a163cff9a4eee4fc45864c7053b 288 Gene3D G3DSA:3.40.50.300 66 283 9.0E-45 T 23-10-2018 A3L04_08560 79fd1a163cff9a4eee4fc45864c7053b 288 Pfam PF02463 RecF/RecN/SMC N terminal domain 43 277 7.6E-13 T 23-10-2018 IPR003395 RecF/RecN/SMC, N-terminal A3L04_06955 3b28dcf7f5dc26258b9337c8f5b1233a 102 Pfam PF03992 Antibiotic biosynthesis monooxygenase 10 68 2.0E-5 T 23-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A3L04_06955 3b28dcf7f5dc26258b9337c8f5b1233a 102 SUPERFAMILY SSF54909 3 69 3.72E-8 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L04_09190 66162912839a3012f1d16f02ef0f0c80 401 Gene3D G3DSA:1.20.1250.20 8 381 9.7E-31 T 23-10-2018 A3L04_09190 66162912839a3012f1d16f02ef0f0c80 401 SUPERFAMILY SSF103473 11 379 1.7E-30 T 23-10-2018 IPR036259 MFS transporter superfamily A3L04_09190 66162912839a3012f1d16f02ef0f0c80 401 Pfam PF07690 Major Facilitator Superfamily 10 348 2.8E-17 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L04_05410 c6f001829f79debb2c131c4d5f9b486c 430 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 304 392 1.2E-6 T 23-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A3L04_06750 225646aea81285ef2eee99afccc7751e 238 Gene3D G3DSA:3.40.50.300 5 237 3.7E-65 T 23-10-2018 A3L04_02120 71d1ab9b691b0dba9bc4a726b05f942e 537 Pfam PF05124 S-layer like family, C-terminal region 396 511 3.4E-10 T 23-10-2018 IPR022651 S-layer protein, C-terminal A3L04_07645 4467765bd4b9eff400585ab6a5b1c0c5 284 PIRSF PIRSF016175 4 283 1.4E-128 T 23-10-2018 IPR016648 Uncharacterised conserved protein UCP016175, prenyltransferase beta-subunit-related A3L04_07645 4467765bd4b9eff400585ab6a5b1c0c5 284 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 243 276 0.8 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 A3L04_07645 4467765bd4b9eff400585ab6a5b1c0c5 284 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 9 29 0.16 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 A3L04_07645 4467765bd4b9eff400585ab6a5b1c0c5 284 SUPERFAMILY SSF48239 7 106 8.64E-9 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L04_07645 4467765bd4b9eff400585ab6a5b1c0c5 284 SUPERFAMILY SSF48239 125 277 2.27E-16 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L04_05685 c889cb6af1475343cf7b9bf1d7ba7b8e 267 PIRSF PIRSF006648 4 256 1.9E-15 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L04_05685 c889cb6af1475343cf7b9bf1d7ba7b8e 267 Pfam PF01061 ABC-2 type transporter 10 221 2.6E-8 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A3L04_00675 f0b740dd00207d3d37780b96f4e5233f 219 Pfam PF09840 Uncharacterized protein conserved in archaea (DUF2067) 9 196 1.4E-49 T 23-10-2018 IPR019202 Protein of unknown function DUF2067 A3L04_04890 8083496da64dbaf592e2f204ad4b0203 528 Pfam PF03169 OPT oligopeptide transporter protein 215 522 1.1E-19 T 23-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 A3L04_04890 8083496da64dbaf592e2f204ad4b0203 528 Pfam PF03169 OPT oligopeptide transporter protein 17 230 3.0E-8 T 23-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 A3L04_06355 b2d051392ac0d46d97c0cf0e55cf4137 156 Gene3D G3DSA:1.20.58.2050 2 152 5.0E-37 T 23-10-2018 IPR038437 GINS complex, subunit Psf3 superfamily Reactome: R-HSA-176974 A3L04_02540 27c64d9107bbe5660c41091749d4ae67 412 Pfam PF01943 Polysaccharide biosynthesis protein 10 278 2.2E-29 T 23-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A3L04_02540 27c64d9107bbe5660c41091749d4ae67 412 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 330 410 7.8E-17 T 23-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A3L04_03025 f9ef99185a4cce3ec046e9b7917cf622 262 Gene3D G3DSA:3.40.50.300 11 253 2.2E-72 T 23-10-2018 A3L04_03665 41efa51679906495391ef4ebecfe4004 285 Pfam PF06195 Protein of unknown function (DUF996) 30 150 2.0E-7 T 23-10-2018 IPR010397 Protein of unknown function DUF996 A3L04_05690 f4b8815e7bb1203954515b4d4f4f69eb 251 Pfam PF01061 ABC-2 type transporter 17 205 8.8E-10 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A3L04_08835 d156f23ee11f7d3ac51ca2926e0eb846 500 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 67 218 2.0E-9 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A3L04_07620 a3ec588927320965bc099ec62bd8e32b 84 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 28 79 6.1E-22 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A3L04_02320 cf55e5f473407caea4e5a8efa3acc77a 162 SUPERFAMILY SSF103165 2 160 7.85E-62 T 23-10-2018 IPR036902 Ta1353-like superfamily A3L04_02320 cf55e5f473407caea4e5a8efa3acc77a 162 Gene3D G3DSA:3.40.1520.10 1 162 1.1E-74 T 23-10-2018 IPR036902 Ta1353-like superfamily A3L04_02320 cf55e5f473407caea4e5a8efa3acc77a 162 Pfam PF04008 Adenosine specific kinase 7 160 4.0E-64 T 23-10-2018 IPR007153 Adenosine specific kinase A3L04_10795 aa5893a709e90b42fae607498a14e356 254 Pfam PF01925 Sulfite exporter TauE/SafE 8 244 5.3E-60 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A3L04_10235 db1cfa2010bcefc43ac4b083ee444c87 197 Pfam PF16147 Domain of unknown function (DUF4855) 2 116 7.5E-11 T 23-10-2018 IPR032329 Protein of unknown function DUF4855 A3L04_03330 36222a332f5c951314470002a8922a30 158 Pfam PF06197 Protein of unknown function (DUF998) 11 156 9.1E-9 T 23-10-2018 IPR009339 Protein of unknown function DUF998 A3L04_02690 1e4e91d1c8840961bb7bc3000b8fd344 443 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 64 189 7.6E-8 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A3L04_04600 9b62c90ee0ea940bc3447af7af88ee3e 110 Pfam PF01435 Peptidase family M48 11 99 5.4E-7 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A3L04_08050 673e6934883ba71ea913038fa8107232 88 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 82 2.4E-13 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A3L04_02740 510791e23f9911bf1f7f1877c3ce9866 292 Pfam PF03547 Membrane transport protein 152 288 1.2E-8 T 23-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A3L04_02740 510791e23f9911bf1f7f1877c3ce9866 292 Pfam PF03547 Membrane transport protein 6 128 3.1E-7 T 23-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A3L04_04655 379196fc74eac6b1e7658d41e09b9bba 208 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 4 188 2.2E-46 T 23-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 A3L04_07320 02b23307bed7836c310ca901c1413496 187 PIRSF PIRSF019678 1 182 4.1E-66 T 23-10-2018 IPR010397 Protein of unknown function DUF996 A3L04_07320 02b23307bed7836c310ca901c1413496 187 Pfam PF06195 Protein of unknown function (DUF996) 30 164 1.3E-34 T 23-10-2018 IPR010397 Protein of unknown function DUF996 A3L04_01970 f1c613d7652177f91427323587300b13 245 Pfam PF05763 Protein of unknown function (DUF835) 120 236 8.8E-39 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L04_07610 0fb5791266f3f94a336efc808d8db366 85 Pfam PF13244 Domain of unknown function (DUF4040) 14 79 1.4E-16 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A3L04_08750 b5ae12f2d2e592d99ad675b346f7262c 134 SUPERFAMILY SSF103481 44 133 5.75E-13 T 23-10-2018 A3L04_08750 b5ae12f2d2e592d99ad675b346f7262c 134 Pfam PF00892 EamA-like transporter family 4 134 9.4E-24 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L04_07565 9bbeb2cbcd7ac3f8ce7e17430e1809a4 321 Pfam PF00146 NADH dehydrogenase 13 314 1.6E-57 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_07515 71a72ae83762d55d254de22c69acc839 309 Pfam PF00146 NADH dehydrogenase 8 306 9.1E-55 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L04_10450 3599788b6aa1309592a186d8500833bd 280 Pfam PF00892 EamA-like transporter family 141 270 2.2E-13 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L04_10450 3599788b6aa1309592a186d8500833bd 280 Pfam PF00892 EamA-like transporter family 8 133 9.5E-18 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L04_10450 3599788b6aa1309592a186d8500833bd 280 SUPERFAMILY SSF103481 47 134 1.2E-8 T 23-10-2018 A3L04_10450 3599788b6aa1309592a186d8500833bd 280 SUPERFAMILY SSF103481 194 275 1.16E-9 T 23-10-2018 A3L04_08065 52540ee28e87b58604f56fef6ca1fcfd 235 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 97 220 5.1E-17 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A3L04_09575 23bef622693ab65cfd9fffa88a025a4c 220 Gene3D G3DSA:3.40.50.300 1 218 1.2E-35 T 23-10-2018 A3L04_07490 a95476c9a17a356dfdd6773085134e4d 94 Pfam PF13244 Domain of unknown function (DUF4040) 14 77 2.2E-19 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A3L04_05485 73818136c2be1865020a66e82673160a 264 Pfam PF02535 ZIP Zinc transporter 112 259 6.7E-20 T 23-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 A3L04_08480 841c4f78d923210b1f37d4fbca1b2438 447 Pfam PF10117 McrBC 5-methylcytosine restriction system component 57 387 1.3E-62 T 23-10-2018 IPR019292 5-methylcytosine restriction system component A3L04_00800 99a3c07956982cbc02bde3aab84f7c11 99 SUPERFAMILY SSF52540 2 97 3.19E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L04_05320 851c6f7377c4ea779a18d59812ba4d1d 90 SUPERFAMILY SSF56784 4 58 4.18E-5 T 23-10-2018 IPR036412 HAD-like superfamily A3L04_01550 9f4a72894469005eb3de65ded501bdd9 176 Pfam PF01944 Stage II sporulation protein M 38 167 1.7E-25 T 23-10-2018 IPR002798 Stage II sporulation protein M-like A3L04_03010 2666a7985d4d8bba8afbecafb9aa809a 137 Pfam PF12760 Transposase zinc-ribbon domain 19 66 8.9E-7 T 23-10-2018 IPR024442 Transposase, zinc-ribbon A3L04_01500 3f29a125824fa10a908db8e659a50335 262 Pfam PF05763 Protein of unknown function (DUF835) 87 213 2.0E-29 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L04_04875 ee5e3cf4ab91d20237ec052a438733f3 307 Pfam PF06675 Protein of unknown function (DUF1177) 38 303 7.4E-140 T 23-10-2018 IPR009561 Protein of unknown function DUF1177 A3L04_00335 97b2476162e93778b31834c02c843bd7 391 Pfam PF12698 ABC-2 family transporter protein 24 380 3.0E-39 T 23-10-2018 A3L04_10505 c976abaf16a99947094853a9e3a95b68 200 Pfam PF06510 Protein of unknown function (DUF1102) 41 187 8.5E-55 T 23-10-2018 IPR009482 Protein of unknown function DUF1102