locus-tag	class	description
CL1_0002	COG0720	synthase
CL1_0008	COG1013	pyruvate-flavodoxin oxidoreductase activity
CL1_0009	COG0674	pyruvate-flavodoxin oxidoreductase activity
CL1_0009	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CL1_0011	COG1013	pyruvate-flavodoxin oxidoreductase activity
CL1_0012	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CL1_0012	COG0674	pyruvate-flavodoxin oxidoreductase activity
CL1_0017	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CL1_0021	COG1744	ABC transporter substrate-binding protein PnrA-like
CL1_0025	COG0803	Belongs to the bacterial solute-binding protein 9 family
CL1_0029	COG0215	cysteine-tRNA ligase activity
CL1_0035	COG0352	thiamine-phosphate diphosphorylase activity
CL1_0035	COG0351	phosphomethylpyrimidine kinase
CL1_0036	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
CL1_0038	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CL1_0039	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CL1_0043	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CL1_0043	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CL1_0044	COG0307	riboflavin synthase, alpha
CL1_0045	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CL1_0045	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CL1_0046	COG1505	serine-type exopeptidase activity
CL1_0071	COG2361	Protein of unknown function DUF86
CL1_0072	COG1363	Peptidase, m42
CL1_0074	COG2409	Drug exporters of the RND superfamily
CL1_0082	COG2096	Adenosyltransferase
CL1_0085	COG1546	Belongs to the CinA family
CL1_0085	COG1058	Belongs to the CinA family
CL1_0087	COG1872	DUF167
CL1_0090	COG0423	glycine-tRNA ligase activity
CL1_0094	COG0534	Mate efflux family protein
CL1_0098	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
CL1_0101	COG0006	proline dipeptidase activity
CL1_0107	COG1918	ferrous iron import across plasma membrane
CL1_0107	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CL1_0109	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CL1_0114	COG0730	response to heat
CL1_0116	COG0730	response to heat
CL1_0118	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CL1_0119	COG0442	prolyl-tRNA aminoacylation
CL1_0121	COG2192	nodulation
CL1_0123	COG0436	Aminotransferase
CL1_0125	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CL1_0126	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
CL1_0128	COG1515	deoxyribonuclease V activity
CL1_0132	COG0569	domain protein
CL1_0135	COG1476	TRANSCRIPTIONal
CL1_0137	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CL1_0143	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
CL1_0149	COG0719	Fe-S assembly protein
CL1_0150	COG0396	ATPase activity
CL1_0155	COG0640	Transcriptional regulator
CL1_0157	COG1522	sequence-specific DNA binding
CL1_0158	COG1836	PFAM Integral membrane protein DUF92
CL1_0159	COG0301	tRNA thio-modification
CL1_0159	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CL1_0179	COG0018	arginyl-trna synthetase
CL1_0183	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CL1_0188	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CL1_0190	COG1863	multisubunit Na H antiporter MnhE subunit
CL1_0191	COG2212	antiporter activity
CL1_0192	COG1320	monovalent cation:proton antiporter activity
CL1_0194	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CL1_0194	COG2111	Na H antiporter
CL1_0195	COG1006	Multisubunit Na H antiporter MnhC subunit
CL1_0196	COG0651	ATP synthesis coupled electron transport
CL1_0197	COG0651	ATP synthesis coupled electron transport
CL1_0199	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CL1_0200	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CL1_0201	COG0649	NAD binding
CL1_0206	COG1522	sequence-specific DNA binding
CL1_0216	COG1881	PFAM PEBP family protein
CL1_0223	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CL1_0225	COG0602	queuosine metabolic process
CL1_0234	COG0359	binds to the 23S rRNA
CL1_0234	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CL1_0237	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CL1_0237	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CL1_0248	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
CL1_0251	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CL1_0254	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CL1_0256	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CL1_0256	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CL1_0263	COG0010	Belongs to the arginase family
CL1_0266	COG0475	glutathione-regulated potassium exporter activity
CL1_0268	COG0038	chloride channel
CL1_0270	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CL1_0273	COG0726	polysaccharide deacetylase
CL1_0278	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CL1_0280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CL1_0286	COG0252	asparaginase activity
CL1_0287	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CL1_0288	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CL1_0290	COG1968	undecaprenyl-diphosphatase activity
CL1_0293	COG0517	IMP dehydrogenase activity
CL1_0293	COG0516	GMP reductase activity
CL1_0295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CL1_0296	COG1122	ATPase activity
CL1_0304	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CL1_0307	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CL1_0309	COG1185	polyribonucleotide nucleotidyltransferase activity
CL1_0326	COG0616	signal peptide processing
CL1_0328	COG0628	permease
CL1_0329	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CL1_0334	COG1131	(ABC) transporter
CL1_0337	COG0556	nucleotide-excision repair
CL1_0338	COG0101	tRNA pseudouridine synthase activity
CL1_0342	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CL1_0343	COG1063	alcohol dehydrogenase
CL1_0344	COG2894	cell division
CL1_0349	COG0504	CTP synthase activity
CL1_0355	COG0585	pseudouridine synthase activity
CL1_0358	COG0017	Asparaginyl-tRNA synthetase
CL1_0360	COG1418	mRNA catabolic process
CL1_0365	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CL1_0370	COG1110	DNA topoisomerase II activity
CL1_0374	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CL1_0374	COG0045	succinate-CoA ligase (ADP-forming) activity
CL1_0374	COG1042	CoA-binding domain protein
CL1_0379	COG1203	CRISPR-associated helicase, Cas3
CL1_0381	COG1518	maintenance of DNA repeat elements
CL1_0383	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CL1_0389	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CL1_0400	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CL1_0401	COG0081	regulation of translation
CL1_0405	COG0717	Belongs to the dCTP deaminase family
CL1_0410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CL1_0412	COG0058	SHG alpha-glucan phosphorylase activity
CL1_0416	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CL1_0419	COG2271	Major facilitator Superfamily
CL1_0420	COG2814	Major facilitator Superfamily
CL1_0421	COG0584	glycerophosphoryl diester phosphodiesterase
CL1_0422	COG0584	glycerophosphoryl diester phosphodiesterase
CL1_0424	COG0579	oxidoreductase
CL1_0436	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CL1_0437	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CL1_0440	COG0085	RNA polymerase activity
CL1_0441	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CL1_0442	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CL1_0446	COG0049	tRNA binding
CL1_0451	COG0436	Aminotransferase
CL1_0459	COG1185	polyribonucleotide nucleotidyltransferase activity
CL1_0462	COG0310	cobalt ion transport
CL1_0465	COG1122	ATPase activity
CL1_0471	COG2140	Oxalate decarboxylase
CL1_0475	COG1234	tRNA 3'-trailer cleavage
CL1_0482	COG0489	protein tyrosine kinase activity
CL1_0484	COG0746	molybdenum cofactor guanylyltransferase activity
CL1_0485	COG0298	carbon dioxide binding
CL1_0486	COG0409	Hydrogenase expression formation protein
CL1_0487	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CL1_0489	COG1895	HEPN domain
CL1_0492	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CL1_0495	COG0731	radical SAM domain protein
CL1_0495	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CL1_0500	COG0446	pyridine nucleotide-disulphide oxidoreductase
CL1_0503	COG1404	Belongs to the peptidase S8 family
CL1_0508	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CL1_0508	COG0574	Belongs to the PEP-utilizing enzyme family
CL1_0509	COG0534	Mate efflux family protein
CL1_0510	COG0534	Mate efflux family protein
CL1_0511	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CL1_0535	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CL1_0538	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CL1_0539	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CL1_0542	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CL1_0543	COG0733	neurotransmitter:sodium symporter activity
CL1_0545	COG0347	Belongs to the P(II) protein family
CL1_0546	COG1543	Belongs to the glycosyl hydrolase 57 family
CL1_0549	COG0864	Transcriptional regulator
CL1_0557	COG0006	proline dipeptidase activity
CL1_0558	COG0495	leucyl-tRNA aminoacylation
CL1_0561	COG0477	Major facilitator Superfamily
CL1_0563	COG0142	geranyltranstransferase activity
CL1_0566	COG1304	FMN binding
CL1_0569	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CL1_0570	COG1355	regulation of microtubule-based process
CL1_0571	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CL1_0572	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CL1_0573	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CL1_0576	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CL1_0579	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CL1_0581	COG1522	sequence-specific DNA binding
CL1_0586	COG0052	Belongs to the universal ribosomal protein uS2 family
CL1_0587	COG0148	phosphopyruvate hydratase activity
CL1_0590	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CL1_0591	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CL1_0595	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CL1_0596	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CL1_0597	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CL1_0598	COG1028	Short-chain dehydrogenase reductase Sdr
CL1_0600	COG1102	Psort location Cytoplasmic, score
CL1_0605	COG0200	Binds to the 23S rRNA
CL1_0606	COG1841	ribosomal large subunit assembly
CL1_0607	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CL1_0608	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CL1_0611	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CL1_0612	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CL1_0614	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CL1_0616	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CL1_0617	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CL1_0618	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CL1_0620	COG0023	Translation Initiation Factor
CL1_0621	COG0255	Belongs to the universal ribosomal protein uL29 family
CL1_0622	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CL1_0623	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CL1_0624	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CL1_0625	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CL1_0626	COG0089	rRNA binding
CL1_0627	COG0088	Forms part of the polypeptide exit tunnel
CL1_0628	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CL1_0633	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CL1_0642	COG0543	2 iron, 2 sulfur cluster binding
CL1_0644	COG3259	Nickel-dependent hydrogenase
CL1_0647	COG0430	RNA-3'-phosphate cyclase activity
CL1_0652	COG1372	Participates in initiation and elongation during chromosome replication
CL1_0652	COG0305	Participates in initiation and elongation during chromosome replication
CL1_0654	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CL1_0656	COG0511	ligase activity, forming carbon-carbon bonds
CL1_0656	COG5016	pyruvate
CL1_0657	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CL1_0658	COG0517	IMP dehydrogenase activity
CL1_0658	COG1125	glycine betaine transport
CL1_0667	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CL1_0668	COG1185	polyribonucleotide nucleotidyltransferase activity
CL1_0679	COG1013	pyruvate-flavodoxin oxidoreductase activity
CL1_0684	COG1335	isochorismatase
CL1_0686	COG2050	protein possibly involved in aromatic compounds catabolism
CL1_0686	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CL1_0687	COG1695	Transcriptional regulator
CL1_0692	COG1185	polyribonucleotide nucleotidyltransferase activity
CL1_0698	COG0417	DNA replication proofreading
CL1_0700	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CL1_0700	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CL1_0702	COG2078	PFAM AMMECR1 domain protein
CL1_0703	COG0011	TIGRFAM Protein of
CL1_0708	COG1178	ABC-type Fe3 transport system permease component
CL1_0711	COG2252	PERMEase
CL1_0718	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CL1_0720	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CL1_0721	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CL1_0731	COG0668	transmembrane transport
CL1_0732	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CL1_0732	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CL1_0734	COG2264	protein methyltransferase activity
CL1_0747	COG2234	aminopeptidase activity
CL1_0764	COG2264	protein methyltransferase activity
CL1_0776	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CL1_0776	COG0519	Catalyzes the synthesis of GMP from XMP
CL1_0779	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CL1_0779	COG0519	Catalyzes the synthesis of GMP from XMP
CL1_0781	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CL1_0782	COG0047	phosphoribosylformylglycinamidine synthase activity
CL1_0785	COG0151	Belongs to the GarS family
CL1_0786	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CL1_0787	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CL1_0788	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CL1_0791	COG1201	RNA secondary structure unwinding
CL1_0792	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CL1_0793	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CL1_0794	COG3383	formate dehydrogenase (NAD+) activity
CL1_0795	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CL1_0796	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CL1_0797	COG0157	Belongs to the NadC ModD family
CL1_0799	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CL1_0800	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CL1_0803	COG0516	GMP reductase activity
CL1_0803	COG0517	IMP dehydrogenase activity
CL1_0806	COG0864	Transcriptional regulator
CL1_0816	COG0459	protein refolding
CL1_0827	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CL1_0828	COG0463	Glycosyl transferase, family 2
CL1_0836	COG0438	transferase activity, transferring glycosyl groups
CL1_0837	COG3119	arylsulfatase activity
CL1_0838	COG0534	Mate efflux family protein
CL1_0840	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CL1_0846	COG0714	Associated with various cellular activities
CL1_0856	COG0438	transferase activity, transferring glycosyl groups
CL1_0862	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CL1_0865	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CL1_0866	COG1373	ATPase (AAA superfamily
CL1_0867	COG0482	sulfurtransferase activity
CL1_0874	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CL1_0877	COG1487	ribonuclease activity
CL1_0880	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CL1_0882	COG0297	glycogen (starch) synthase activity
CL1_0883	COG1378	Sugar-specific transcriptional regulator TrmB
CL1_0886	COG1175	transmembrane transport
CL1_0887	COG3833	ABC-type maltose transport systems, permease component
CL1_0889	COG3842	ATPase activity
CL1_0891	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CL1_0893	COG1234	tRNA 3'-trailer cleavage
CL1_0894	COG1297	OPT oligopeptide transporter protein
CL1_0896	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CL1_0898	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CL1_0902	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CL1_0909	COG0174	glutamine synthetase
CL1_0911	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CL1_0913	COG4608	Belongs to the ABC transporter superfamily
CL1_0914	COG0444	Belongs to the ABC transporter superfamily
CL1_0915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CL1_0916	COG0601	transmembrane transport
CL1_0919	COG0543	2 iron, 2 sulfur cluster binding
CL1_0924	COG1606	tRNA processing
CL1_0927	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CL1_0928	COG1394	ATPase activity, coupled to movement of substances
CL1_0930	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
CL1_0931	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
CL1_0933	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
CL1_0935	COG1269	ATP hydrolysis coupled proton transport
CL1_0937	COG0569	domain protein
CL1_0938	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CL1_0940	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CL1_0943	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CL1_0954	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CL1_0957	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CL1_0965	COG0475	glutathione-regulated potassium exporter activity
CL1_0966	COG0516	GMP reductase activity
CL1_0966	COG0517	IMP dehydrogenase activity
CL1_0967	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CL1_0970	COG0037	tRNA processing
CL1_0972	COG1449	Belongs to the glycosyl hydrolase 57 family
CL1_0977	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CL1_0977	COG4651	solute:proton antiporter activity
CL1_0980	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CL1_0982	COG2046	Belongs to the sulfate adenylyltransferase family
CL1_0989	COG0730	response to heat
CL1_0991	COG3119	arylsulfatase activity
CL1_0996	COG3119	arylsulfatase activity
CL1_0997	COG1216	Glycosyl transferase, family 2
CL1_0997	COG0463	Glycosyl transferase, family 2
CL1_0998	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CL1_0999	COG0037	tRNA processing
CL1_1007	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CL1_1008	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CL1_1012	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CL1_1016	COG0714	Associated with various cellular activities
CL1_1020	COG1047	Peptidyl-prolyl cis-trans
CL1_1027	COG1160	GTP binding
CL1_1031	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CL1_1031	COG0116	Belongs to the methyltransferase superfamily
CL1_1033	COG0179	Fumarylacetoacetate (FAA) hydrolase
CL1_1037	COG0640	Transcriptional regulator
CL1_1042	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CL1_1042	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CL1_1043	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CL1_1043	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CL1_1045	COG0402	S-adenosylhomocysteine deaminase activity
CL1_1047	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CL1_1053	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CL1_1079	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CL1_1081	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CL1_1087	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CL1_1089	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CL1_1092	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CL1_1092	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CL1_1100	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CL1_1102	COG0314	molybdopterin synthase activity
CL1_1106	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CL1_1107	COG1522	sequence-specific DNA binding
CL1_1117	COG0148	phosphopyruvate hydratase activity
CL1_1119	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CL1_1122	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CL1_1123	COG0492	ferredoxin-NADP+ reductase activity
CL1_1125	COG2255	four-way junction helicase activity
CL1_1130	COG0650	Formate hydrogenlyase subunit 4
CL1_1132	COG3261	NADH dehydrogenase
CL1_1132	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CL1_1133	COG3260	NADH ubiquinone oxidoreductase 20
CL1_1135	COG0651	ATP synthesis coupled electron transport
CL1_1140	COG1320	monovalent cation:proton antiporter activity
CL1_1141	COG2212	antiporter activity
CL1_1142	COG1863	multisubunit Na H antiporter MnhE subunit
CL1_1143	COG0437	4 iron, 4 sulfur cluster binding
CL1_1144	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CL1_1144	COG0493	'glutamate synthase
CL1_1145	COG2116	formate transmembrane transporter activity
CL1_1147	COG0437	4 iron, 4 sulfur cluster binding
CL1_1148	COG3383	formate dehydrogenase (NAD+) activity
CL1_1151	COG3259	Nickel-dependent hydrogenase
CL1_1152	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CL1_1153	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CL1_1158	COG0306	phosphate transporter
CL1_1161	COG0517	IMP dehydrogenase activity
CL1_1161	COG1125	glycine betaine transport
CL1_1171	COG1506	peptidase
CL1_1171	COG0823	Involved in the tonB-independent uptake of proteins
CL1_1171	COG4946	Tricorn protease homolog
CL1_1180	COG0681	Belongs to the peptidase S26 family
CL1_1181	COG0095	Lipoate-protein ligase
CL1_1183	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CL1_1188	COG1346	cytolysis
CL1_1189	COG1380	Effector of murein hydrolase LrgA
CL1_1192	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CL1_1194	COG1573	uracil-dna glycosylase
CL1_1195	COG1757	Na H antiporter
CL1_1199	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CL1_1203	COG1522	sequence-specific DNA binding
CL1_1205	COG1980	fructose-bisphosphate aldolase activity
CL1_1207	COG1233	COG1233 Phytoene dehydrogenase and related
CL1_1224	COG2226	methyltransferase
CL1_1227	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CL1_1228	COG0589	response to stress
CL1_1229	COG1628	Protein of unknown function DUF99
CL1_1230	COG1324	tolerance protein
CL1_1231	COG1254	Belongs to the acylphosphatase family
CL1_1233	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CL1_1238	COG0489	protein tyrosine kinase activity
CL1_1239	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CL1_1240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CL1_1243	COG1013	pyruvate-flavodoxin oxidoreductase activity
CL1_1244	COG0674	pyruvate-flavodoxin oxidoreductase activity
CL1_1246	COG1013	pyruvate-flavodoxin oxidoreductase activity
CL1_1247	COG0674	pyruvate-flavodoxin oxidoreductase activity
CL1_1250	COG0306	phosphate transporter
CL1_1251	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CL1_1258	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CL1_1259	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CL1_1261	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CL1_1262	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CL1_1265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CL1_1268	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CL1_1272	COG0312	modulator of DNA gyrase
CL1_1273	COG0312	modulator of DNA gyrase
CL1_1282	COG0434	BtpA family
CL1_1286	COG1988	membrane-bound metal-dependent
CL1_1293	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CL1_1294	COG0540	Belongs to the ATCase OTCase family
CL1_1301	COG3885	ferrous iron binding
CL1_1301	COG2078	PFAM AMMECR1 domain protein
CL1_1304	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CL1_1305	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CL1_1306	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CL1_1309	COG0456	acetyltransferase
CL1_1309	COG1214	PFAM Peptidase M22, glycoprotease
CL1_1311	COG0156	8-amino-7-oxononanoate synthase activity
CL1_1317	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CL1_1320	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CL1_1324	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CL1_1329	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CL1_1331	COG2814	Major facilitator Superfamily
CL1_1333	COG1446	asparaginase
CL1_1338	COG2814	Major facilitator Superfamily
CL1_1339	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CL1_1344	COG2131	deaminase
CL1_1345	COG0501	Belongs to the peptidase M48B family
CL1_1347	COG0535	radical SAM domain protein
CL1_1348	COG2414	aldehyde ferredoxin oxidoreductase
CL1_1349	COG1404	Belongs to the peptidase S8 family
CL1_1353	COG2151	metal-sulfur cluster biosynthetic enzyme
CL1_1354	COG1141	Ferredoxin
CL1_1356	COG1028	Short-chain dehydrogenase reductase Sdr
CL1_1359	COG0493	'glutamate synthase
CL1_1359	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CL1_1360	COG0543	2 iron, 2 sulfur cluster binding
CL1_1364	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CL1_1365	COG0167	dihydroorotate dehydrogenase activity
CL1_1369	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CL1_1374	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CL1_1377	COG2814	Major facilitator Superfamily
CL1_1379	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CL1_1382	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CL1_1385	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CL1_1387	COG0693	protein deglycase activity
CL1_1393	COG2095	MarC family integral membrane protein
CL1_1394	COG1765	OsmC-like protein
CL1_1396	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CL1_1397	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CL1_1398	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CL1_1403	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CL1_1412	COG0123	including yeast histone deacetylase and acetoin utilization protein
CL1_1413	COG0025	NhaP-type Na H and K H
CL1_1417	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CL1_1422	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CL1_1423	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CL1_1427	COG0440	acetolactate synthase activity
CL1_1428	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CL1_1434	COG2212	antiporter activity
CL1_1435	COG1863	multisubunit Na H antiporter MnhE subunit
CL1_1436	COG0509	glycine decarboxylation via glycine cleavage system
CL1_1439	COG0493	'glutamate synthase
CL1_1439	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CL1_1440	COG0543	2 iron, 2 sulfur cluster binding
CL1_1446	COG0747	negative chemotaxis
CL1_1447	COG0601	transmembrane transport
CL1_1449	COG0444	Belongs to the ABC transporter superfamily
CL1_1450	COG4608	Belongs to the ABC transporter superfamily
CL1_1457	COG1131	(ABC) transporter
CL1_1458	COG1476	TRANSCRIPTIONal
CL1_1463	COG2119	membrane
CL1_1467	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CL1_1468	COG1192	Involved in chromosome partitioning
CL1_1470	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CL1_1470	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CL1_1472	COG0284	orotidine-5'-phosphate decarboxylase activity
CL1_1475	COG1213	nucleotidyl transferase
CL1_1475	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CL1_1478	COG1131	(ABC) transporter
CL1_1482	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CL1_1482	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CL1_1487	COG1850	ribulose-bisphosphate carboxylase activity
CL1_1497	COG1851	Uncharacterised protein family (UPF0128)
CL1_1501	COG1832	CoA-binding protein
CL1_1506	COG1160	GTP binding
CL1_1512	COG0725	ABC transporter, periplasmic molybdate-binding protein
CL1_1513	COG4149	molybdate abc transporter
CL1_1514	COG3842	ATPase activity
CL1_1517	COG0714	Associated with various cellular activities
CL1_1522	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CL1_1523	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CL1_1527	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CL1_1528	COG0560	Phosphoserine phosphatase
CL1_1539	COG1056	cytidyltransferase-related domain
CL1_1539	COG1051	belongs to the nudix hydrolase family
CL1_1545	COG2226	methyltransferase
CL1_1556	COG0778	Nitroreductase
CL1_1558	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CL1_1569	COG0071	Belongs to the small heat shock protein (HSP20) family
CL1_1570	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CL1_1570	COG1793	dna ligase
CL1_1576	COG0482	sulfurtransferase activity
CL1_1587	COG0045	succinate-CoA ligase (ADP-forming) activity
CL1_1587	COG1042	CoA-binding domain protein
CL1_1587	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CL1_1590	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CL1_1592	COG0303	'Molybdopterin
CL1_1593	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CL1_1594	COG1373	ATPase (AAA superfamily
CL1_1598	COG0009	L-threonylcarbamoyladenylate synthase
CL1_1601	COG0367	asparagine synthase
CL1_1603	COG2894	cell division
CL1_1607	COG0424	maF-like protein
CL1_1609	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CL1_1609	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CL1_1611	COG0346	lactoylglutathione lyase activity
CL1_1613	COG1196	nuclear chromosome segregation
CL1_1616	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CL1_1622	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CL1_1626	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CL1_1629	COG2894	cell division
CL1_1630	COG0330	HflC and HflK could
CL1_1633	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CL1_1639	COG2247	cell wall binding repeat
CL1_1639	COG0860	N-Acetylmuramoyl-L-alanine amidase
CL1_1641	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CL1_1642	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CL1_1643	COG1984	allophanate hydrolase subunit 2
CL1_1645	COG1454	alcohol dehydrogenase
CL1_1647	COG0483	inositol monophosphate 1-phosphatase activity
CL1_1649	COG1199	ATP-dependent helicase activity
CL1_1653	COG1489	DNA binding
CL1_1654	COG1215	transferase activity, transferring glycosyl groups
CL1_1661	COG0301	tRNA thio-modification
CL1_1663	COG0301	tRNA thio-modification
CL1_1664	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CL1_1666	COG0045	succinate-CoA ligase (ADP-forming) activity
CL1_1666	COG1042	CoA-binding domain protein
CL1_1666	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CL1_1673	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CL1_1680	COG0126	phosphoglycerate kinase activity
CL1_1683	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CL1_1685	COG3842	ATPase activity
CL1_1686	COG4208	sulfate ABC transporter
CL1_1691	COG1111	helicase
CL1_1691	COG1205	dead DEAH box helicase
CL1_1695	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CL1_1696	COG1122	ATPase activity
CL1_1697	COG1268	BioY protein
CL1_1703	COG1506	peptidase
CL1_1703	COG0823	Involved in the tonB-independent uptake of proteins
CL1_1703	COG4946	Tricorn protease homolog
CL1_1706	COG1444	tRNA N-acetyltransferase activity
CL1_1712	COG0017	Asparaginyl-tRNA synthetase
CL1_1713	COG0402	S-adenosylhomocysteine deaminase activity
CL1_1716	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CL1_1720	COG0631	protein serine/threonine phosphatase activity
CL1_1721	COG0515	serine threonine protein kinase
CL1_1721	COG2815	serine threonine protein kinase
CL1_1723	COG0631	protein serine/threonine phosphatase activity
CL1_1724	COG0515	serine threonine protein kinase
CL1_1724	COG2815	serine threonine protein kinase
CL1_1726	COG2815	serine threonine protein kinase
CL1_1726	COG0515	serine threonine protein kinase
CL1_1727	COG2815	serine threonine protein kinase
CL1_1727	COG0515	serine threonine protein kinase
CL1_1736	COG0175	sulfate reduction
CL1_1744	COG0105	UTP biosynthetic process
CL1_1748	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CL1_1753	COG0419	ATPase involved in DNA repair
CL1_1758	COG0084	hydrolase, TatD family'
CL1_1761	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CL1_1762	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CL1_1766	COG1201	RNA secondary structure unwinding
CL1_1769	COG2814	Major facilitator Superfamily
CL1_1772	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CL1_1777	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CL1_1779	COG1342	Belongs to the UPF0251 family
CL1_1790	COG0489	protein tyrosine kinase activity
CL1_1791	COG0455	bacterial-type flagellum organization
CL1_1795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CL1_1796	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CL1_1798	COG2267	carboxylic ester hydrolase activity
CL1_1802	COG0003	Pfam Anion-transporting ATPase
CL1_1804	COG1966	Carbon starvation protein
CL1_1806	COG1830	Aldolase
CL1_1807	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CL1_1807	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CL1_1808	COG1301	dicarboxylic acid transport
CL1_1810	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CL1_1811	COG1203	CRISPR-associated helicase, Cas3
CL1_1813	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CL1_1814	COG1518	maintenance of DNA repeat elements
CL1_1821	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CL1_1822	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CL1_1822	COG0140	phosphoribosyl-ATP diphosphatase activity
CL1_1823	COG0107	imidazoleglycerol-phosphate synthase activity
CL1_1824	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CL1_1825	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CL1_1826	COG0131	Imidazoleglycerol-phosphate dehydratase
CL1_1828	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CL1_1840	COG2033	superoxide reductase activity
CL1_1841	COG1773	rubredoxin
CL1_1842	COG1592	Rubrerythrin
CL1_1846	COG0778	Nitroreductase
CL1_1849	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CL1_1851	COG2217	Heavy metal translocating P-type atpase
CL1_1853	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CL1_1862	COG0450	alkyl hydroperoxide reductase
CL1_1863	COG0243	molybdopterin cofactor binding
CL1_1871	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CL1_1873	COG0546	phosphoglycolate phosphatase activity
CL1_1877	COG0477	Major facilitator Superfamily
CL1_1878	COG2814	Major facilitator Superfamily
CL1_1880	COG0312	modulator of DNA gyrase
CL1_1884	COG0668	transmembrane transport
CL1_1886	COG1993	acr, cog1993
CL1_1887	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CL1_1895	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CL1_1898	COG0531	amino acid
CL1_1899	COG0563	adenylate kinase activity
CL1_1902	COG0011	TIGRFAM Protein of
CL1_1903	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CL1_1905	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CL1_1910	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CL1_1912	COG1121	(ABC) transporter
CL1_1920	COG1401	restriction endodeoxyribonuclease activity
CL1_1922	COG1469	GTP cyclohydrolase I activity
CL1_1928	COG1078	dGTPase activity
CL1_1929	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CL1_1931	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CL1_1932	COG0051	transcription antitermination factor activity, RNA binding
CL1_1933	COG2414	aldehyde ferredoxin oxidoreductase
CL1_1935	COG2264	protein methyltransferase activity
CL1_1940	COG2403	cyclic 2,3-diphosphoglycerate synthetase activity
CL1_1942	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CL1_1946	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CL1_1948	COG1121	(ABC) transporter
CL1_1953	COG1353	crispr-associated protein
CL1_1955	COG1337	RAMP superfamily
CL1_1960	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CL1_1961	COG1518	maintenance of DNA repeat elements
CL1_1965	COG1739	Uncharacterized protein family UPF0029
CL1_1971	COG1216	Glycosyl transferase, family 2
CL1_1972	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CL1_1976	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CL1_1976	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CL1_1982	COG0315	cyclic pyranopterin monophosphate synthase activity
CL1_1985	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CL1_1989	COG0459	protein refolding
CL1_1991	COG0501	Belongs to the peptidase M48B family
CL1_1992	COG0402	S-adenosylhomocysteine deaminase activity
CL1_1995	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CL1_1996	COG0492	ferredoxin-NADP+ reductase activity
CL1_1997	COG1335	isochorismatase
CL1_1998	COG1028	Short-chain dehydrogenase reductase Sdr
CL1_1999	COG1899	peptidyl-lysine modification to peptidyl-hypusine
CL1_2005	COG1078	dGTPase activity
CL1_2010	COG0303	'Molybdopterin
CL1_2011	COG0521	Mo-molybdopterin cofactor biosynthetic process
CL1_2014	COG1492	cobalamin metabolic process
CL1_2019	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CL1_2022	COG1573	uracil-dna glycosylase
CL1_2023	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CL1_2024	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CL1_2025	COG2226	methyltransferase
CL1_2026	COG0525	valine-tRNA ligase activity
CL1_2029	COG1373	ATPase (AAA superfamily
CL1_2031	COG0312	modulator of DNA gyrase
CL1_2035	COG1794	racemase activity, acting on amino acids and derivatives
CL1_2036	COG0012	GTP binding
CL1_2038	COG1522	sequence-specific DNA binding
CL1_2039	COG0163	prenyltransferase activity